# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RNase_P_p30 PF01876.16 KFX85687.1 - 4.1e-48 163.7 0.0 6.8e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 TFIIS_M PF07500.14 KFX85689.1 - 2e-28 99.1 0.7 4.2e-28 98.1 0.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFX85689.1 - 3.9e-18 65.0 6.1 6.2e-18 64.4 6.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFX85689.1 - 8.3e-10 38.5 0.6 2.4e-09 37.1 0.6 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Arteri_nsp7a PF16749.5 KFX85689.1 - 0.035 14.3 0.2 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha PALP PF00291.25 KFX85690.1 - 1.3e-58 198.8 0.7 1.5e-58 198.6 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KFX85691.1 - 3.6e-42 144.8 0.0 5.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KFX85691.1 - 8.5e-05 22.5 0.2 0.00023 21.1 0.2 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GrpB PF04229.14 KFX85692.1 - 1.4e-38 132.6 0.1 1.7e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 GrpB protein NTP_transf_5 PF14907.6 KFX85692.1 - 0.034 13.8 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase tRNA-synt_2c PF01411.19 KFX85693.1 - 3.3e-206 686.1 1.2 3.3e-206 686.1 1.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFX85693.1 - 1.2e-17 63.7 0.4 2.5e-17 62.7 0.4 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFX85693.1 - 9e-13 48.8 2.4 1.9e-12 47.7 2.4 1.6 1 0 0 1 1 1 1 DHHA1 domain PdaC PF13739.6 KFX85693.1 - 2.1 9.4 5.4 6.1 7.9 3.9 2.7 3 0 0 3 3 3 0 Deacetylase PdaC KLRAQ PF10205.9 KFX85694.1 - 0.62 10.3 3.3 0.28 11.4 0.6 1.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Vps8 PF12816.7 KFX85695.1 - 5.9e-70 234.8 0.1 1.7e-69 233.3 0.0 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFX85695.1 - 1.5e-06 28.1 0.7 0.086 12.7 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KFX85695.1 - 0.0064 16.5 1.2 0.012 15.6 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger zf-RING_UBOX PF13445.6 KFX85695.1 - 0.0077 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX85695.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX85695.1 - 0.092 13.1 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX85695.1 - 0.18 12.1 0.2 0.39 11.1 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain ANAPC4_WD40 PF12894.7 KFX85700.1 - 1.3e-26 92.7 0.1 1.8e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX85700.1 - 9.3e-05 23.1 0.0 0.5 11.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.12 KFX85700.1 - 0.0052 14.8 0.1 0.0081 14.2 0.1 1.2 1 1 0 1 1 1 1 IKI3 family Carbam_trans_C PF16861.5 KFX85700.1 - 0.098 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus Adap_comp_sub PF00928.21 KFX85701.1 - 7.2e-19 68.2 0.7 1e-18 67.7 0.7 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFX85701.1 - 1.8e-08 34.4 0.1 3.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KFX85701.1 - 0.0021 18.5 0.3 0.0051 17.2 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Imm1 PF14430.6 KFX85701.1 - 0.11 13.1 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm1 DUF2420 PF10336.9 KFX85702.1 - 6.5e-16 58.3 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 KFX85703.1 - 9.5e-108 359.8 15.8 1.1e-107 359.5 15.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFX85703.1 - 0.00031 20.9 6.7 0.00031 20.9 6.7 3.3 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_S3_C PF00189.20 KFX85704.1 - 8.7e-25 87.1 0.2 5.5e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFX85704.1 - 6.4e-12 45.1 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KFX85704.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KFX85704.1 - 0.11 12.3 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Coilin N-terminus Myotub-related PF06602.14 KFX85705.1 - 3.5e-148 493.2 0.0 4.3e-148 492.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain tRNA_synthFbeta PF17759.1 KFX85706.1 - 2.9e-42 144.5 0.0 4.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFX85706.1 - 7.2e-33 112.7 0.4 1.3e-31 108.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFX85706.1 - 6.1e-26 91.1 0.0 1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFX85706.1 - 6.6e-18 64.8 0.0 1.9e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.17 KFX85706.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein HEAT PF02985.22 KFX85707.1 - 8.7e-37 122.0 19.6 0.015 15.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KFX85707.1 - 6e-35 119.5 7.4 1.4e-11 44.6 0.0 8.3 4 2 4 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 KFX85707.1 - 7.2e-13 48.7 8.8 0.0082 16.6 0.0 8.6 8 2 2 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFX85707.1 - 2.7e-12 47.1 3.6 0.007 16.9 0.1 7.6 5 2 4 9 9 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFX85707.1 - 1.6e-10 41.2 11.4 0.0014 18.7 0.2 6.1 4 1 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFX85707.1 - 3.5e-08 32.5 7.2 3.1e-05 22.7 1.3 3.7 2 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KFX85707.1 - 5.9e-06 26.4 4.2 1.5 9.0 0.1 5.2 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFX85707.1 - 0.00017 21.2 4.3 3 7.4 0.1 4.5 2 2 3 5 5 5 2 CLASP N terminal Proteasom_PSMB PF10508.9 KFX85707.1 - 0.026 13.0 4.6 0.45 8.9 0.0 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 KFX85707.1 - 0.04 14.2 0.6 15 5.8 0.0 3.6 2 1 2 4 4 4 0 Apoptosis regulator M11L like Ecm29 PF13001.7 KFX85707.1 - 0.065 11.9 4.9 9.5 4.8 0.0 4.2 4 1 1 5 5 5 0 Proteasome stabiliser IFRD PF05004.13 KFX85707.1 - 0.12 11.5 0.3 0.77 8.8 0.2 2.6 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KFX85707.1 - 0.24 11.5 4.7 3.3 7.9 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 KFX85709.1 - 8.6e-37 125.6 11.4 2.3e-13 50.6 2.8 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX85709.1 - 3.9e-33 113.4 5.3 3.2e-08 34.0 0.1 7.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KFX85709.1 - 6.7e-30 102.2 20.5 3.6e-06 27.2 0.9 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KFX85709.1 - 2e-28 95.3 6.7 0.00058 20.1 0.1 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 KFX85709.1 - 8.2e-14 51.5 5.7 0.0031 17.8 0.1 5.5 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Borealin PF10512.9 KFX85709.1 - 0.019 14.9 0.0 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 Cell division cycle-associated protein 8 DUF4988 PF16378.5 KFX85709.1 - 0.043 13.5 0.1 5.4 6.6 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function SpoU_sub_bind PF08032.12 KFX85709.1 - 0.058 13.7 0.1 0.9 9.9 0.0 2.8 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF1843 PF08898.10 KFX85709.1 - 0.13 12.8 5.6 9.4 6.8 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF3613 PF12266.8 KFX85709.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) EF-hand_1 PF00036.32 KFX85710.1 - 0.00011 21.5 0.1 0.00022 20.5 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX85710.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFX85710.1 - 0.0099 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KFX85710.1 - 0.035 13.6 0.1 0.069 12.7 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 KFX85710.1 - 0.042 13.7 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 EF-hand domain pair SWIRM PF04433.17 KFX85711.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Syndecan PF01034.20 KFX85712.1 - 0.053 13.5 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain ATP_bind_3 PF01171.20 KFX85717.1 - 4.1e-50 170.1 0.0 7.1e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 KFX85717.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 KFX85717.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Q_salvage PF10343.9 KFX85718.1 - 7e-130 432.7 1.0 8.4e-130 432.4 1.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Spore_YhaL PF14147.6 KFX85718.1 - 0.015 15.0 0.1 0.032 13.9 0.1 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL ThiF PF00899.21 KFX85719.1 - 7.9e-73 244.8 0.0 1.2e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KFX85719.1 - 6.7e-25 87.5 0.9 6.7e-25 87.5 0.9 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFX85719.1 - 6.7e-08 32.8 2.8 4.7e-06 26.7 0.7 2.7 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KFX85719.1 - 0.00063 20.2 0.7 0.003 18.0 0.0 2.5 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFX85719.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX85719.1 - 0.083 13.5 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2407_C PF13373.6 KFX85719.1 - 0.15 12.3 0.6 0.35 11.1 0.6 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain Endonuc_Holl PF10107.9 KFX85719.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.0 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase adh_short_C2 PF13561.6 KFX85720.1 - 1.5e-56 191.6 1.0 1.7e-56 191.4 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX85720.1 - 2.8e-53 180.3 0.8 3.4e-53 180.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX85720.1 - 3.5e-14 53.1 0.9 5.3e-14 52.5 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX85720.1 - 3.1e-07 30.1 0.2 5.8e-06 25.9 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX85720.1 - 3.6e-05 23.0 0.1 4.9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFX85720.1 - 0.00072 19.5 0.3 0.00085 19.3 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 KFX85720.1 - 0.00079 19.3 0.1 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 KFX85720.1 - 0.0038 16.9 0.2 0.011 15.4 0.1 1.7 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KFX85720.1 - 0.022 14.2 0.0 0.081 12.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KFX85720.1 - 0.025 14.5 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFX85720.1 - 0.075 12.4 0.1 1.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 KFX85720.1 - 0.089 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Skp1_POZ PF03931.15 KFX85721.1 - 2.9e-06 27.3 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 KFX85722.1 - 5e-45 153.3 0.0 9.3e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain GRP PF07172.11 KFX85722.1 - 9 7.1 29.3 19 6.0 29.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family zf-ZPR1 PF03367.13 KFX85723.1 - 5.4e-109 361.1 2.0 1.4e-56 190.7 0.0 2.9 3 0 0 3 3 3 2 ZPR1 zinc-finger domain Rpr2 PF04032.16 KFX85723.1 - 2.8e-11 43.6 3.8 2.8e-11 43.6 3.8 2.5 3 0 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 KFX85723.1 - 0.0061 16.5 0.1 0.0061 16.5 0.1 3.6 5 0 0 5 5 5 1 Nudix N-terminal DUF4674 PF15719.5 KFX85723.1 - 0.17 11.9 7.8 0.47 10.5 7.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) Haem_bd PF14376.6 KFX85723.1 - 1.2 9.0 3.3 0.53 10.2 0.1 2.0 2 0 0 2 2 2 0 Haem-binding domain WD40 PF00400.32 KFX85728.1 - 2.6e-36 123.0 20.6 3e-07 31.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX85728.1 - 5.3e-15 55.5 0.0 0.00019 21.6 0.1 4.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX85728.1 - 0.00016 21.6 0.0 0.11 12.4 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX85728.1 - 0.00041 19.4 0.1 3.8 6.4 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX85728.1 - 0.01 15.2 0.0 0.64 9.3 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain Ran_BP1 PF00638.18 KFX85729.1 - 1.9e-48 163.8 2.2 4.2e-48 162.7 2.2 1.6 1 0 0 1 1 1 1 RanBP1 domain A_deaminase PF00962.22 KFX85729.1 - 5.4e-30 104.8 0.0 8.4e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase WH1 PF00568.23 KFX85729.1 - 0.0021 18.0 0.4 0.009 15.9 0.4 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFX85729.1 - 0.009 16.3 0.2 0.016 15.4 0.2 1.5 1 0 0 1 1 1 1 VID27 PH-like domain YEATS PF03366.16 KFX85730.1 - 5.2e-19 68.0 0.0 1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFX85730.1 - 8.9e-08 32.2 0.3 1.8e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3083 PF11281.8 KFX85730.1 - 0.012 15.0 0.1 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3083) DUF4604 PF15377.6 KFX85731.1 - 4.2e-23 82.6 17.8 4.8e-23 82.5 17.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2868 PF11067.8 KFX85731.1 - 0.36 10.3 2.7 0.25 10.8 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) SRP-alpha_N PF04086.13 KFX85731.1 - 0.73 9.7 10.2 0.89 9.4 10.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 KFX85731.1 - 5 5.8 6.1 5.3 5.7 6.1 1.1 1 0 0 1 1 1 0 Presenilin Glyco_transf_15 PF01793.16 KFX85732.1 - 4.3e-96 322.0 11.9 3.3e-95 319.1 11.9 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_C2 PF00648.21 KFX85734.1 - 2e-32 112.4 0.0 2.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Gemini_C4 PF01492.17 KFX85734.1 - 0.011 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein DUF4775 PF16001.5 KFX85734.1 - 0.08 12.3 0.4 0.12 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) MIT PF04212.18 KFX85734.1 - 0.14 12.2 2.5 0.25 11.5 2.5 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SAM_2 PF07647.17 KFX85735.1 - 1e-09 38.3 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFX85735.1 - 5.1e-05 23.6 0.1 0.00011 22.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ALIX_LYPXL_bnd PF13949.6 KFX85735.1 - 0.0065 15.8 1.0 0.01 15.1 1.0 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV IGR PF09597.10 KFX85735.1 - 0.063 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif DUF4508 PF14969.6 KFX85735.1 - 0.14 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) MerR-DNA-bind PF09278.11 KFX85735.1 - 0.22 12.1 0.7 0.62 10.6 0.7 1.8 1 0 0 1 1 1 0 MerR, DNA binding TPR_19 PF14559.6 KFX85736.1 - 1.6e-13 50.9 19.2 5.7e-05 23.6 2.2 7.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX85736.1 - 7.6e-12 44.5 19.6 0.00013 21.9 0.1 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX85736.1 - 6.4e-10 39.0 20.0 0.038 14.8 0.0 9.8 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX85736.1 - 1.9e-08 34.1 0.3 0.045 14.2 0.1 5.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX85736.1 - 2.1e-07 30.5 13.9 0.00042 19.9 0.3 6.3 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.6 KFX85736.1 - 1.9e-06 28.1 30.5 0.06 13.6 1.6 8.4 7 3 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX85736.1 - 3.5e-06 26.7 38.7 0.0016 18.4 0.1 12.3 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX85736.1 - 3.7e-06 26.5 38.7 6.1e-05 22.7 0.2 10.7 12 0 0 12 12 12 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFX85736.1 - 1.3e-05 25.7 0.8 0.86 10.0 0.2 3.6 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 KFX85736.1 - 2.2e-05 24.6 15.4 0.12 12.6 3.4 5.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFX85736.1 - 0.00022 21.0 18.1 0.043 13.8 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX85736.1 - 0.0006 20.4 22.9 0.52 11.0 0.2 7.1 6 2 0 7 7 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFX85736.1 - 0.0035 17.6 16.4 0.23 11.8 2.0 5.6 5 2 1 7 7 5 2 Tetratricopeptide repeat RPN7 PF10602.9 KFX85736.1 - 0.0039 16.9 0.1 5.3 6.7 0.1 3.3 3 1 0 3 3 3 2 26S proteasome subunit RPN7 ChAPs PF09295.10 KFX85736.1 - 0.0068 15.4 4.5 0.61 9.0 0.6 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 KFX85736.1 - 0.073 13.2 3.9 51 4.1 0.3 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX85736.1 - 0.085 13.5 23.4 0.96 10.2 0.1 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat BTAD PF03704.17 KFX85736.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.2 4 2 1 5 5 3 0 Bacterial transcriptional activator domain Sec23_trunk PF04811.15 KFX85737.1 - 1.3e-80 270.5 0.0 1.8e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFX85737.1 - 5.7e-31 107.1 0.3 1.4e-30 105.9 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFX85737.1 - 5.5e-25 87.2 0.1 1.6e-24 85.7 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFX85737.1 - 4e-15 55.6 5.2 7.6e-15 54.7 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFX85737.1 - 1.5e-13 50.5 0.0 4.2e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFX85737.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L22 PF00237.19 KFX85738.1 - 4.6e-41 139.2 0.1 6.7e-41 138.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Lipl32 PF12103.8 KFX85738.1 - 0.028 14.1 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order LTD PF00932.19 KFX85738.1 - 0.088 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Sugar_tr PF00083.24 KFX85742.1 - 1.9e-31 109.4 26.4 5e-23 81.7 12.5 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX85742.1 - 3.4e-29 101.9 36.0 4.9e-24 84.9 17.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Dicty_REP PF05086.12 KFX85743.1 - 1.3 6.9 8.2 1.5 6.7 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 KFX85743.1 - 5.1 7.1 30.4 0.25 11.3 17.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LVIVD PF08309.11 KFX85744.1 - 0.6 9.5 5.6 0.17 11.2 1.3 2.1 2 0 0 2 2 2 0 LVIVD repeat Fic PF02661.18 KFX85745.1 - 5.9e-21 75.2 0.0 1.7e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family DSPc PF00782.20 KFX85746.1 - 3.7e-19 68.9 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX85746.1 - 0.004 16.7 0.1 0.0055 16.3 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.16 KFX85747.1 - 7.9e-32 110.5 26.8 1.2e-31 110.0 26.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3425 PF11905.8 KFX85747.1 - 6.1e-22 77.9 0.1 1.2e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1691 PF07950.11 KFX85747.1 - 0.051 14.3 0.1 0.17 12.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) adh_short PF00106.25 KFX85748.1 - 8e-34 116.8 0.0 1.1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX85748.1 - 3.2e-26 92.3 0.0 4.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX85748.1 - 0.0013 18.7 0.1 0.0029 17.5 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX85748.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFX85748.1 - 0.12 12.3 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pap_E4 PF02711.14 KFX85750.1 - 0.21 12.6 3.3 1.1 10.3 0.0 2.1 1 1 1 2 2 2 0 E4 protein AIM24 PF01987.17 KFX85753.1 - 3.6e-50 170.6 1.2 4.3e-50 170.3 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PSII_BNR PF14870.6 KFX85753.1 - 0.053 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Death PF00531.22 KFX85754.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Death domain RNA_pol_Rpb1_R PF05001.13 KFX85754.1 - 7.3 7.1 7.2 45 4.7 2.5 3.5 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Med1 PF10744.9 KFX85756.1 - 8.1e-110 367.7 0.0 1.4e-109 366.9 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 RHH_1 PF01402.21 KFX85756.1 - 0.069 13.1 0.1 1.8 8.6 0.1 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Resolvase PF00239.21 KFX85756.1 - 0.36 10.9 2.7 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Resolvase, N terminal domain Diphthamide_syn PF01866.17 KFX85757.1 - 0.22 10.9 0.1 0.38 10.2 0.1 1.3 1 0 0 1 1 1 0 Putative diphthamide synthesis protein FAD_binding_3 PF01494.19 KFX85761.1 - 2.9e-06 26.8 0.0 1.3e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain FERM_F2 PF18377.1 KFX85761.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain bZIP_1 PF00170.21 KFX85762.1 - 0.00074 19.6 7.6 0.0011 19.0 7.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX85762.1 - 0.023 14.8 8.2 0.039 14.1 8.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Ebola_NP PF05505.12 KFX85762.1 - 0.12 10.7 0.8 0.14 10.4 0.8 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein MARVEL PF01284.23 KFX85766.1 - 0.0089 16.1 13.2 0.019 15.0 13.3 1.5 1 1 1 2 2 2 1 Membrane-associating domain DUF998 PF06197.13 KFX85766.1 - 0.15 11.6 8.4 0.22 11.1 7.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Coatomer_WDAD PF04053.14 KFX85767.1 - 1.3e-146 489.1 0.0 2.2e-146 488.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFX85767.1 - 1.2e-92 310.8 0.0 1.7e-92 310.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFX85767.1 - 1.7e-35 120.4 18.3 2.4e-07 31.3 0.2 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX85767.1 - 3.6e-07 30.4 0.5 0.065 13.5 0.0 5.5 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX85767.1 - 0.027 14.3 1.1 5.6 6.8 0.0 3.6 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFX85767.1 - 0.086 11.5 8.1 4.4 5.8 0.1 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 KFX85767.1 - 0.088 12.7 3.4 0.15 11.9 0.0 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS Glyco_transf_24 PF18404.1 KFX85768.1 - 4.2e-149 495.2 0.7 6.6e-149 494.6 0.7 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KFX85768.1 - 2.8e-69 233.9 0.1 7.8e-67 225.9 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KFX85768.1 - 1e-47 162.8 0.5 1.9e-46 158.7 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFX85768.1 - 4.3e-44 150.7 0.0 1.7e-43 148.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KFX85768.1 - 4.6e-44 149.6 4.8 1.2e-43 148.2 0.1 3.6 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFX85768.1 - 2.5e-38 130.5 0.0 5.4e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KFX85768.1 - 0.00016 21.3 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 KFX85769.1 - 2.2e-24 85.2 0.4 3.7e-22 78.1 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 KFX85769.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease DUF677 PF05055.12 KFX85769.1 - 0.21 10.4 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PBP1_TM PF14812.6 KFX85771.1 - 0.39 11.1 4.8 0.51 10.8 4.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KFX85771.1 - 1.2 8.8 4.7 1.4 8.6 4.7 1.1 1 0 0 1 1 1 0 FAM176 family Abhydrolase_1 PF00561.20 KFX85772.1 - 8e-16 58.4 0.0 1.4e-13 51.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX85772.1 - 7e-09 35.3 0.0 3.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX85772.1 - 3.1e-08 34.5 0.0 4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFX85772.1 - 0.00065 18.5 0.0 0.0026 16.5 0.0 2.1 1 1 0 1 1 1 1 Ndr family DLH PF01738.18 KFX85772.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Caps_synth PF05704.12 KFX85773.1 - 3.9e-12 46.1 0.0 7.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KFX85773.1 - 3.8e-05 24.2 0.0 6.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NmrA PF05368.13 KFX85774.1 - 1.2e-24 87.2 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX85774.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF4327 PF14217.6 KFX85774.1 - 0.15 12.3 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Defensin_beta PF00711.19 KFX85775.1 - 0.24 11.4 3.1 0.21 11.7 1.2 1.9 2 0 0 2 2 2 0 Beta defensin tRNA-synt_1c PF00749.21 KFX85776.1 - 6.7e-70 235.5 0.0 1.4e-41 142.4 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Pkinase PF00069.25 KFX85776.1 - 1.8e-29 102.9 0.0 9.1e-29 100.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain tRNA-synt_1c_C PF03950.18 KFX85776.1 - 2e-28 99.4 0.0 8.3e-28 97.4 0.0 2.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Pkinase_Tyr PF07714.17 KFX85776.1 - 7.2e-06 25.5 0.0 0.057 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase SNF2_N PF00176.23 KFX85778.1 - 9.1e-59 198.9 0.1 1.4e-58 198.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KFX85778.1 - 2.1e-09 37.1 8.1 4.9e-09 35.9 8.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX85778.1 - 1.1e-08 34.8 4.9 1.1e-08 34.8 4.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX85778.1 - 1.1e-08 35.3 7.7 2.8e-08 33.9 7.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFX85778.1 - 4.3e-06 26.5 7.0 4.3e-06 26.5 7.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX85778.1 - 1.1e-05 25.1 5.5 2.6e-05 24.0 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFX85778.1 - 1.3e-05 25.1 6.9 3.4e-05 23.7 6.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFX85778.1 - 0.00014 22.0 5.2 0.00038 20.7 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFX85778.1 - 0.00022 21.2 5.6 0.00061 19.8 5.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger PrkA PF06798.12 KFX85778.1 - 0.0038 16.9 1.5 0.0038 16.9 1.5 1.8 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain NPV_P10 PF05531.12 KFX85778.1 - 0.076 13.5 1.8 7.6 7.1 0.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-RING_4 PF14570.6 KFX85778.1 - 0.1 12.4 2.4 0.35 10.7 2.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFX85778.1 - 0.22 11.7 7.4 0.49 10.6 7.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFX85778.1 - 0.28 11.3 3.7 0.74 10.0 3.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 KFX85778.1 - 0.57 9.8 4.9 10 5.8 5.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 KFX85778.1 - 0.62 9.8 8.7 0.12 12.1 4.6 1.9 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.7 KFX85778.1 - 3.7 7.7 6.0 20 5.3 3.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Sec10 PF07393.11 KFX85779.1 - 3.1e-163 544.9 0.0 3.9e-163 544.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KFX85779.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX85779.1 - 3.9e-06 26.6 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain RhoGAP PF00620.27 KFX85780.1 - 1.1e-15 57.8 1.7 1.4e-15 57.4 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KFX85780.1 - 6.3e-12 45.4 0.0 2.5e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KFX85780.1 - 1.3e-08 35.0 0.0 5.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain KIP1 PF07765.12 KFX85780.1 - 0.16 12.1 0.1 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 KIP1-like protein DUF2867 PF11066.8 KFX85785.1 - 4e-34 118.0 0.0 5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Lipase_GDSL_2 PF13472.6 KFX85786.1 - 6e-21 75.6 0.1 1e-20 74.9 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX85786.1 - 9.9e-17 61.6 0.0 1.2e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFX85786.1 - 0.087 12.9 0.0 0.92 9.6 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 KFX85787.1 - 8.9e-31 107.1 30.3 5.8e-28 97.8 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 KFX85787.1 - 0.023 14.7 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 PgaD-like protein p450 PF00067.22 KFX85789.1 - 3.1e-45 154.8 0.0 7e-45 153.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.19 KFX85790.1 - 2.6e-36 123.9 12.1 5.9e-36 122.8 12.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L44 Arcadin_1 PF18653.1 KFX85791.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Arcadin 1 TRP PF06011.12 KFX85796.1 - 1.6e-38 132.6 23.0 7.7e-37 127.0 23.0 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX85796.1 - 1.2e-23 84.1 0.1 1.7e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF639 PF04842.12 KFX85796.1 - 1.1 8.6 5.6 0.089 12.2 0.5 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Strabismus PF06638.11 KFX85796.1 - 8.9 4.8 5.2 14 4.2 5.2 1.1 1 0 0 1 1 1 0 Strabismus protein NAD_binding_4 PF07993.12 KFX85799.1 - 1.4e-29 103.1 0.0 1.7e-26 92.9 0.0 2.9 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.13 KFX85799.1 - 2.3e-26 92.8 0.7 1.2e-25 90.4 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KFX85799.1 - 1.6e-22 80.3 0.1 9.5e-22 77.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding AMP-binding PF00501.28 KFX85799.1 - 4.6e-19 68.3 0.0 7.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KFX85799.1 - 4.9e-13 49.1 0.0 9.5e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX85799.1 - 1.4e-07 31.7 0.0 6.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KFX85799.1 - 0.00018 21.9 0.3 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX85799.1 - 0.00092 19.5 0.0 0.0064 16.7 0.1 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KFX85799.1 - 0.0016 18.6 0.3 0.15 12.2 0.2 2.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KFX85799.1 - 0.0021 18.0 0.1 0.39 10.6 0.0 2.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KFX85799.1 - 0.018 14.1 0.0 0.09 11.8 0.1 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.24 KFX85800.1 - 4.3e-39 135.1 0.1 5e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX85800.1 - 7.6e-07 29.3 0.0 4e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX85800.1 - 2.1e-06 27.2 0.0 0.0065 15.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX85800.1 - 2.9e-05 23.5 0.0 4.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFX85800.1 - 0.00011 21.4 0.0 0.032 13.3 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 KFX85800.1 - 0.00067 20.2 0.0 0.0017 18.8 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFX85800.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KFX85800.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KFX85800.1 - 0.0053 16.0 0.0 0.022 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX85800.1 - 0.0058 16.6 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFX85800.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KFX85800.1 - 0.022 13.9 0.7 0.22 10.6 0.0 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A Epimerase PF01370.21 KFX85800.1 - 0.027 13.9 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 KFX85800.1 - 0.028 13.2 0.0 2.5 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KFX85800.1 - 0.054 13.2 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KFX85800.1 - 0.073 12.4 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.12 KFX85800.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein KR PF08659.10 KFX85800.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.21 KFX85800.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Het-C PF07217.11 KFX85800.1 - 0.22 10.0 0.0 0.32 9.5 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Cyclin_N PF00134.23 KFX85801.1 - 0.0068 16.1 0.0 0.024 14.4 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain MTES_1575 PF18741.1 KFX85801.1 - 0.1 12.8 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 REase_MTES_1575 COesterase PF00135.28 KFX85802.1 - 7.6e-83 279.1 0.1 8.7e-83 278.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX85802.1 - 0.008 16.1 0.4 0.032 14.1 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX85802.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Zn_clus PF00172.18 KFX85803.1 - 1.1e-07 31.8 12.2 2.3e-07 30.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX85804.1 - 3.4e-25 88.6 0.2 5.6e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX85805.1 - 5.9e-31 107.7 22.9 8e-31 107.2 22.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 KFX85806.1 - 3.8e-33 114.4 0.0 4.4e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 KFX85806.1 - 0.04 14.0 0.1 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 PA domain Glyco_hydro_75 PF07335.11 KFX85809.1 - 4.7e-65 218.8 0.5 5.9e-65 218.5 0.5 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SRP1_TIP1 PF00660.17 KFX85809.1 - 0.17 12.0 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 Seripauperin and TIP1 family Pectate_lyase_3 PF12708.7 KFX85810.1 - 2.3e-49 168.2 20.4 1e-41 143.2 9.5 2.8 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX85810.1 - 0.0062 16.2 1.2 0.12 12.1 0.1 2.7 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.24 KFX85811.1 - 9.5e-81 271.9 21.8 1.1e-80 271.7 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX85811.1 - 7e-29 100.8 16.1 7e-29 100.8 16.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX85811.1 - 0.00054 18.4 2.8 0.012 14.0 1.1 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family NmrA PF05368.13 KFX85813.1 - 4.7e-18 65.6 0.0 6.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX85813.1 - 1.6e-08 34.7 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX85813.1 - 8.1e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFX85813.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 KFX85813.1 - 0.019 14.0 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KFX85813.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX85813.1 - 0.1 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KFX85813.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cellulase PF00150.18 KFX85816.1 - 2.4e-12 46.9 0.2 4.6e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf_Hakai PF18408.1 KFX85816.1 - 0.045 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain Meckelin PF09773.9 KFX85816.1 - 0.057 11.5 0.3 0.081 11.0 0.3 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) FAD_binding_4 PF01565.23 KFX85817.1 - 3.7e-22 78.6 0.1 7.1e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.24 KFX85818.1 - 0.057 13.4 3.3 0.16 12.0 3.5 1.8 1 1 0 1 1 1 0 Sodium/calcium exchanger protein GPDPase_memb PF10110.9 KFX85818.1 - 0.063 12.1 0.1 0.44 9.3 0.0 1.9 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase FixS PF03597.15 KFX85818.1 - 1.2 8.9 3.9 22 4.8 0.0 2.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type HlyIII PF03006.20 KFX85818.1 - 1.2 8.8 6.8 1.8 8.3 2.1 2.9 2 1 0 2 2 2 0 Haemolysin-III related YjbE PF11106.8 KFX85818.1 - 1.7 8.9 7.1 0.14 12.4 1.5 2.0 2 1 0 2 2 2 0 Exopolysaccharide production protein YjbE FAD_binding_3 PF01494.19 KFX85822.1 - 3.9e-09 36.2 5.7 3.4e-07 29.9 1.5 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX85822.1 - 0.00099 19.3 1.1 0.0022 18.2 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX85822.1 - 0.0044 16.3 1.3 0.014 14.7 0.7 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX85822.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KFX85822.1 - 0.027 14.0 5.2 0.13 11.8 2.9 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFX85822.1 - 0.064 12.5 0.6 0.11 11.8 0.6 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.10 KFX85822.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 KFX85822.1 - 0.21 10.6 1.0 0.88 8.6 0.9 1.8 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KFX85823.1 - 2.6e-17 62.8 27.8 7.3e-16 58.0 25.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2530 PF10745.9 KFX85823.1 - 0.22 11.8 0.0 0.22 11.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF2070 PF09843.9 KFX85823.1 - 0.84 7.8 7.0 1.2 7.3 7.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_12 PF13424.6 KFX85826.1 - 5.6e-11 42.6 29.1 0.014 15.7 0.0 9.7 9 1 2 11 11 11 4 Tetratricopeptide repeat AAA_22 PF13401.6 KFX85826.1 - 1.5e-09 38.2 1.0 7.2e-09 36.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain TPR_19 PF14559.6 KFX85826.1 - 5.5e-07 30.0 8.5 0.042 14.4 0.1 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX85826.1 - 1.1e-06 28.3 10.1 0.34 10.8 0.1 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX85826.1 - 1.7e-06 28.4 2.1 16 6.6 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFX85826.1 - 4.8e-05 23.8 0.1 0.00021 21.7 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 KFX85826.1 - 0.00056 20.5 0.5 30 5.4 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.12 KFX85826.1 - 0.0034 17.3 0.0 0.035 14.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.17 KFX85826.1 - 0.0053 16.8 20.9 1.8 8.9 0.3 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat DUF3137 PF11335.8 KFX85826.1 - 0.012 15.6 0.1 0.1 12.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3137) TPR_7 PF13176.6 KFX85826.1 - 0.013 15.5 18.2 28 5.0 0.1 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX85826.1 - 0.24 11.7 19.9 1.8 9.0 0.4 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX85826.1 - 1.5 8.8 14.7 1.7 8.6 0.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Bystin PF05291.11 KFX85828.1 - 6e-131 436.1 0.0 7.6e-131 435.7 0.0 1.1 1 0 0 1 1 1 1 Bystin CAP_N PF01213.19 KFX85829.1 - 1.3 8.4 10.7 1.9 7.9 10.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Myb_Cef PF11831.8 KFX85833.1 - 0.0001 22.0 9.7 0.00011 21.9 9.7 1.0 1 0 0 1 1 1 1 pre-mRNA splicing factor component Di19_C PF14571.6 KFX85833.1 - 0.059 13.9 6.2 0.067 13.7 6.2 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal B277 PF17623.2 KFX85833.1 - 0.098 11.7 2.9 0.11 11.5 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function Trp_halogenase PF04820.14 KFX85834.1 - 1.4e-13 50.5 0.0 5.2e-05 22.3 0.0 3.5 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KFX85834.1 - 0.00083 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX85834.1 - 0.0015 17.8 0.1 0.019 14.2 0.0 2.4 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFX85834.1 - 0.0015 18.7 0.0 0.034 14.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 KFX85834.1 - 0.0018 16.9 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 KFX85834.1 - 0.028 15.0 0.0 0.15 12.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hen1_L PF12623.7 KFX85834.1 - 0.13 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 HORMA PF02301.18 KFX85835.1 - 9.3e-31 107.1 0.0 1.6e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KFX85835.1 - 0.01 15.7 10.6 0.021 14.7 10.6 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KFX85835.1 - 0.048 13.6 5.0 0.094 12.6 5.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFX85835.1 - 0.084 12.4 4.6 0.15 11.7 4.6 1.4 1 0 0 1 1 1 0 PHD-finger ABC_tran PF00005.27 KFX85837.1 - 7.4e-51 172.3 0.0 5.1e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX85837.1 - 5.3e-27 95.2 41.5 7e-22 78.4 19.1 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFX85837.1 - 4e-11 42.8 2.6 0.016 14.6 0.0 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX85837.1 - 4.2e-08 33.4 3.8 0.059 13.2 0.0 4.2 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX85837.1 - 2.5e-06 27.5 0.2 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFX85837.1 - 2.8e-06 27.6 0.3 0.15 12.4 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX85837.1 - 9.8e-06 25.2 0.2 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX85837.1 - 2.2e-05 24.9 0.5 0.34 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KFX85837.1 - 4.5e-05 24.0 0.2 0.043 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX85837.1 - 8.4e-05 23.1 0.0 0.031 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX85837.1 - 0.0002 21.6 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KFX85837.1 - 0.0005 20.5 0.3 3.7 8.0 0.0 3.7 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KFX85837.1 - 0.00099 19.2 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFX85837.1 - 0.00099 18.9 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KFX85837.1 - 0.001 18.8 0.1 0.3 10.8 0.0 3.2 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 KFX85837.1 - 0.0014 18.4 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX85837.1 - 0.0021 17.6 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 KFX85837.1 - 0.0042 17.5 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KFX85837.1 - 0.015 15.2 0.1 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 KFX85837.1 - 0.019 13.8 1.0 0.15 10.9 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 KFX85837.1 - 0.019 15.0 0.2 8.6 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 KFX85837.1 - 0.023 14.8 0.9 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 KFX85837.1 - 0.024 14.6 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PRK PF00485.18 KFX85837.1 - 0.028 14.1 0.1 0.08 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 KFX85837.1 - 0.053 13.1 0.1 30 4.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KFX85837.1 - 0.061 12.9 0.3 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KFX85837.1 - 0.063 12.5 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KFX85837.1 - 0.065 13.5 0.1 28 4.9 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KFX85837.1 - 0.069 12.9 0.0 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 KFX85837.1 - 0.09 11.6 0.8 3.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_35 PF14516.6 KFX85837.1 - 0.14 11.0 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_11 PF13086.6 KFX85837.1 - 0.15 11.8 0.1 23 4.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFX85837.1 - 0.17 11.0 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 KFX85837.1 - 0.23 11.1 0.8 9.4 5.8 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3290 PF11694.8 KFX85837.1 - 1.1 9.2 3.8 0.57 10.2 0.2 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3290) F-box PF00646.33 KFX85838.1 - 2.7e-05 23.9 0.1 6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX85838.1 - 0.012 15.5 0.5 0.031 14.2 0.5 1.7 1 0 0 1 1 1 0 F-box-like Actin PF00022.19 KFX85839.1 - 6e-16 58.1 0.0 9.5e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Actin MitMem_reg PF13012.6 KFX85839.1 - 8.5e-11 42.3 3.5 5e-10 39.8 3.5 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KFX85839.1 - 1.6e-07 31.3 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease IDEAL PF08858.10 KFX85839.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 IDEAL domain RRM_1 PF00076.22 KFX85840.1 - 0.0053 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.9 KFX85840.1 - 0.013 15.7 3.0 0.039 14.2 3.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cullin PF00888.22 KFX85840.1 - 0.035 12.7 0.7 0.056 12.1 0.7 1.2 1 0 0 1 1 1 0 Cullin family Promethin PF16015.5 KFX85842.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Promethin RTA1 PF04479.13 KFX85843.1 - 8.7e-55 185.5 8.9 8.7e-55 185.5 8.9 1.8 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KFX85844.1 - 3.2e-07 30.4 6.5 5.4e-07 29.6 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX85844.1 - 0.063 12.1 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain ACP PF06857.11 KFX85844.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) DUF4690 PF15756.5 KFX85846.1 - 6.2e-05 23.5 0.4 0.00023 21.7 0.4 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SARAF PF06682.12 KFX85846.1 - 0.00015 21.6 0.3 0.00026 20.7 0.3 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SH3_9 PF14604.6 KFX85846.1 - 0.0016 18.2 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX85846.1 - 0.0043 16.6 0.2 0.0086 15.7 0.2 1.5 1 0 0 1 1 1 1 SH3 domain Bacteriocin_IIc PF10439.9 KFX85846.1 - 0.0074 16.4 8.6 0.053 13.6 1.1 2.8 2 0 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide Syndecan PF01034.20 KFX85846.1 - 0.019 14.8 2.7 0.043 13.7 2.7 1.5 1 0 0 1 1 1 0 Syndecan domain DAP10 PF07213.11 KFX85846.1 - 0.078 12.9 1.1 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 DAP10 membrane protein Glycophorin_A PF01102.18 KFX85846.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 KFX85846.1 - 0.39 10.5 1.9 1.3 8.9 1.9 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_YMGG PF13441.6 KFX85846.1 - 2.8 7.7 16.4 4.8 7.0 4.5 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF2613 PF11021.8 KFX85846.1 - 4.3 7.5 7.1 0.32 11.1 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Gly-zipper_Omp PF13488.6 KFX85846.1 - 5.6 7.0 15.6 4.7 7.3 2.9 2.6 2 0 0 2 2 2 0 Glycine zipper Jnk-SapK_ap_N PF09744.9 KFX85851.1 - 8.3 6.6 13.7 32 4.7 6.8 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 KFX85852.1 - 2.1e-68 230.5 0.0 2.8e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX85852.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFX85852.1 - 4.1e-13 49.8 0.1 2.5e-12 47.3 0.1 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KFX85852.1 - 5.9e-09 36.2 0.0 3.2e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KFX85852.1 - 1.7e-08 34.1 0.0 5.4e-08 32.5 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFX85852.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 2.1 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KFX85852.1 - 0.0073 16.0 1.2 1.7 8.2 0.1 3.1 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_15_3 PF03307.14 KFX85852.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 KFX85852.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX85852.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFX85852.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EPL1 PF10513.9 KFX85852.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.4 2 1 0 2 2 1 0 Enhancer of polycomb-like LPD38 PF18857.1 KFX85855.1 - 0.04 14.1 1.6 1.8 8.7 0.1 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 ABM PF03992.16 KFX85856.1 - 4.8e-05 23.4 1.0 0.3 11.2 0.2 2.4 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 KFX85856.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) Zn_clus PF00172.18 KFX85857.1 - 1.3e-05 25.2 9.0 2.6e-05 24.2 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX85857.1 - 0.00027 20.1 0.0 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KFX85858.1 - 6.8e-28 97.5 0.3 8.7e-28 97.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX85858.1 - 1.3e-21 77.3 0.1 1.4e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX85858.1 - 6.5e-08 32.7 0.0 9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX85858.1 - 0.0012 18.8 0.0 0.0052 16.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX85858.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 KFX85862.1 - 2.5e-60 204.2 0.0 4.1e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFX85862.1 - 4.9e-26 91.4 0.0 1.5e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFX85862.1 - 3.2e-07 30.6 0.0 6.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX85862.1 - 0.00048 21.1 1.5 0.0011 19.9 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.20 KFX85864.1 - 8e-49 165.6 0.2 2.6e-48 163.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFX85864.1 - 4.2e-34 118.7 0.0 7e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFX85864.1 - 1.4e-28 99.1 5.9 4.2e-10 39.9 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFX85864.1 - 0.00032 20.5 0.1 0.00052 19.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 KFX85864.1 - 0.0029 17.8 0.0 2.7 8.3 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein HAD PF12710.7 KFX85864.1 - 0.039 14.4 0.0 0.37 11.2 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3795 PF12675.7 KFX85864.1 - 0.33 11.4 2.6 11 6.5 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3795) AflR PF08493.10 KFX85864.1 - 3.3 7.1 6.3 0.28 10.6 0.8 2.0 2 0 0 2 2 2 0 Aflatoxin regulatory protein p450 PF00067.22 KFX85865.1 - 5.9e-44 150.6 0.0 6.9e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KFX85867.1 - 1.8e-32 112.4 0.2 2.3e-32 112.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX85867.1 - 2.1e-23 83.1 0.2 2.9e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX85867.1 - 2.7e-12 47.0 0.0 3.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX85867.1 - 0.0001 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX85867.1 - 0.0034 16.9 0.3 0.012 15.1 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family U-box PF04564.15 KFX85868.1 - 2.4e-05 24.4 0.0 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KFX85868.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein 2C_adapt PF08793.10 KFX85868.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 2-cysteine adaptor domain SNF2_N PF00176.23 KFX85870.1 - 5.9e-65 219.3 0.4 9.7e-65 218.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX85870.1 - 6e-19 68.4 0.0 3.7e-18 65.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX85870.1 - 8.2e-10 38.9 2.5 8.5e-10 38.9 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 KFX85870.1 - 0.00031 21.0 8.0 0.00031 21.0 8.0 3.3 1 1 2 3 3 3 1 HSA DEAD PF00270.29 KFX85870.1 - 0.00063 19.6 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KFX85870.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.1 3 0 0 3 3 3 0 DEAD_2 AAA_25 PF13481.6 KFX85870.1 - 0.27 10.8 4.2 2.3 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 KFX85871.1 - 0.059 13.3 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial carrier protein Cupin_2 PF07883.11 KFX85872.1 - 5.9e-21 74.0 0.2 5e-10 39.0 0.1 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFX85872.1 - 8.9e-18 63.8 1.5 1.5e-14 53.4 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFX85872.1 - 3.9e-06 26.8 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KFX85872.1 - 0.00015 21.9 0.0 0.00044 20.4 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Mrx7 PF10906.8 KFX85872.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 MIOREX complex component 7 Ala_racemase_N PF01168.20 KFX85874.1 - 3.6e-23 82.4 0.0 4.5e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DDE_1 PF03184.19 KFX85877.1 - 4.6e-10 39.4 0.0 9.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HeLo PF14479.6 KFX85878.1 - 3.3e-29 102.2 2.1 5.4e-24 85.2 0.1 2.1 1 1 1 2 2 2 2 Prion-inhibition and propagation DUF1192 PF06698.11 KFX85878.1 - 0.0013 18.7 1.3 0.0021 18.1 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1192) GIDA_assoc PF13932.6 KFX85878.1 - 0.036 14.2 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 GidA associated domain Paxillin PF03535.13 KFX85878.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Paxillin family NACHT PF05729.12 KFX85879.1 - 3.5e-08 33.5 0.0 7.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX85879.1 - 4.5e-07 30.4 0.0 9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KFX85879.1 - 0.003 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF4423 PF14394.6 KFX85879.1 - 0.012 15.4 0.2 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) AAA_22 PF13401.6 KFX85879.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX85879.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFX85879.1 - 0.033 14.8 0.1 0.079 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX85879.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 KFX85879.1 - 0.17 11.9 0.1 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFX85879.1 - 0.18 12.2 0.1 0.47 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KFX85879.1 - 0.2 12.1 0.0 0.5 10.8 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KFX85879.1 - 0.3 10.3 1.1 1 8.5 0.2 1.9 1 1 0 2 2 2 0 KAP family P-loop domain Omega-toxin PF06357.11 KFX85880.1 - 0.031 14.1 0.2 48 3.9 0.0 3.1 3 0 0 3 3 3 0 Omega-atracotoxin DUF1010 PF06231.11 KFX85880.1 - 0.58 10.7 2.7 14 6.3 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1010) F-box PF00646.33 KFX85883.1 - 0.048 13.6 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 F-box domain Cpn60_TCP1 PF00118.24 KFX85887.1 - 8.5e-151 502.9 18.1 9.6e-151 502.7 18.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 KFX85888.1 - 1.2e-40 139.0 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX85888.1 - 8e-07 28.8 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFX85888.1 - 5.8e-05 23.1 0.1 0.00043 20.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX85888.1 - 0.00011 22.4 0.0 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KFX85888.1 - 0.00018 21.6 0.0 0.00083 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFX85888.1 - 0.00065 20.1 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KFX85888.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFX85888.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KFX85888.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX85888.1 - 0.033 13.7 0.0 0.097 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFX85888.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX85888.1 - 0.057 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFX85888.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFX85888.1 - 0.09 12.5 0.0 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFX85888.1 - 0.12 12.3 0.6 9.8 6.0 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFX85888.1 - 0.13 12.8 0.1 0.5 10.9 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KFX85888.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX85888.1 - 0.14 11.9 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFX85888.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Laminin_II PF06009.12 KFX85890.1 - 1.5 8.9 9.6 1.4 8.9 7.2 2.0 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KFX85890.1 - 1.9 8.6 20.1 0.7 10.0 15.9 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFX85890.1 - 3.8 7.9 27.4 0.089 13.2 14.0 2.4 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 KFX85890.1 - 8.6 6.0 29.4 9 5.9 13.2 3.2 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Mito_carr PF00153.27 KFX85891.1 - 2.7e-66 219.5 5.1 4.4e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KFX85891.1 - 0.081 12.7 0.6 0.27 11.0 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) RasGEF PF00617.19 KFX85893.1 - 2.3e-50 171.3 1.4 5.5e-50 170.0 0.5 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFX85893.1 - 2e-16 60.1 0.1 8.8e-16 58.1 0.1 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFX85893.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX85893.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Mitofilin PF09731.9 KFX85894.1 - 6.8e-33 114.4 14.4 8.3e-18 64.6 0.1 2.5 1 1 2 3 3 3 2 Mitochondrial inner membrane protein DUF4533 PF15047.6 KFX85894.1 - 0.1 12.1 3.2 0.53 9.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) DUF1151 PF06625.11 KFX85894.1 - 0.11 12.5 4.8 0.19 11.7 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Ras PF00071.22 KFX85895.1 - 9.6e-59 197.6 0.3 1.1e-58 197.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX85895.1 - 2.7e-36 124.4 0.1 5.8e-36 123.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX85895.1 - 2.2e-15 56.5 0.1 2.7e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX85895.1 - 4.9e-07 29.3 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX85895.1 - 5.1e-07 29.4 0.0 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX85895.1 - 6e-07 29.5 0.0 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX85895.1 - 6.5e-06 26.1 1.3 0.053 13.4 0.3 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFX85895.1 - 0.0072 16.7 0.3 0.016 15.6 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX85895.1 - 0.039 14.2 0.0 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAT PF03417.16 KFX85895.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Syja_N PF02383.18 KFX85896.1 - 8.6e-91 304.6 0.0 1.1e-90 304.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF3224 PF11528.8 KFX85898.1 - 2.1e-16 59.9 1.9 4.3e-16 58.9 1.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3224) AAA PF00004.29 KFX85900.1 - 3.6e-40 137.4 0.0 7.7e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX85900.1 - 1.2e-18 66.8 0.2 2.3e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFX85900.1 - 1.3e-09 37.7 0.0 2.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX85900.1 - 0.00021 21.7 2.1 0.022 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFX85900.1 - 0.00022 21.3 0.1 0.0012 18.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX85900.1 - 0.00036 20.3 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFX85900.1 - 0.00052 20.2 0.9 0.0057 16.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KFX85900.1 - 0.0018 17.8 0.2 0.053 13.0 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KFX85900.1 - 0.0024 18.1 3.3 0.084 13.1 0.0 3.2 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFX85900.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFX85900.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX85900.1 - 0.024 13.8 0.0 0.058 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KFX85900.1 - 0.076 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX85900.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFX85900.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF1768 PF08719.11 KFX85901.1 - 1.9e-37 129.0 0.0 3.5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RR_TM4-6 PF06459.12 KFX85901.1 - 0.55 10.0 22.2 0.97 9.2 22.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vinculin PF01044.19 KFX85901.1 - 1.9 6.6 12.4 2.2 6.4 12.4 1.1 1 0 0 1 1 1 0 Vinculin family TFIIA PF03153.13 KFX85901.1 - 1.9 8.4 22.9 2.2 8.2 22.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 KFX85901.1 - 7.7 6.6 6.4 13 5.9 6.4 1.4 1 0 0 1 1 1 0 DDHD domain DUF1180 PF06679.12 KFX85902.1 - 0.83 10.1 2.8 2.3 8.6 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DnaJ PF00226.31 KFX85903.1 - 1.6e-21 76.2 0.4 2.7e-21 75.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Chitin_synth_1 PF01644.17 KFX85905.1 - 2.4e-75 252.0 0.1 3.5e-75 251.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFX85905.1 - 1.1e-28 99.0 0.0 2.5e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFX85905.1 - 1.9e-20 73.0 7.4 7.3e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KFX85905.1 - 0.0059 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3417 PF11897.8 KFX85907.1 - 0.096 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) zf-C2H2 PF00096.26 KFX85908.1 - 0.00061 20.1 13.5 0.18 12.3 5.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX85908.1 - 0.061 14.2 11.2 1.2 10.2 0.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFX85908.1 - 0.48 10.6 6.1 0.69 10.0 6.1 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-UBP PF02148.19 KFX85908.1 - 2.8 8.3 7.3 3 8.2 1.0 2.5 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ammonium_transp PF00909.21 KFX85912.1 - 1.5e-115 386.1 26.8 1.7e-115 385.9 26.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ytp1 PF10355.9 KFX85913.1 - 1.4e-66 224.6 21.3 1.4e-66 224.6 21.3 2.7 2 2 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFX85913.1 - 7.2e-32 109.3 1.5 7.2e-32 109.3 1.5 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Phage_holin_3_6 PF07332.11 KFX85913.1 - 5.5 7.1 18.8 4.5 7.3 0.6 4.2 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans_2 PF11951.8 KFX85920.1 - 4.9e-24 84.9 6.6 2.1e-23 82.8 6.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KFX85921.1 - 6e-24 84.6 1.0 1.1e-23 83.7 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX85921.1 - 1.1e-15 57.9 1.1 1.4e-15 57.5 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX85921.1 - 1.3e-05 25.2 0.1 2.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX85921.1 - 0.00011 21.7 0.2 0.0014 18.2 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX85921.1 - 0.0077 16.1 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding HOOK PF05622.12 KFX85924.1 - 7.1e-19 67.4 74.4 1.2e-13 50.1 74.8 3.2 2 1 0 2 2 2 2 HOOK protein ZapB PF06005.12 KFX85924.1 - 0.005 17.2 2.8 0.005 17.2 2.8 9.0 5 2 3 8 8 8 2 Cell division protein ZapB GFO_IDH_MocA PF01408.22 KFX85924.1 - 0.0058 17.4 0.3 0.023 15.5 0.3 2.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cnn_1N PF07989.11 KFX85924.1 - 0.0097 16.0 1.2 0.0097 16.0 1.2 8.3 5 3 2 7 7 7 1 Centrosomin N-terminal motif 1 PKcGMP_CC PF16808.5 KFX85924.1 - 0.016 15.1 12.0 0.085 12.7 1.7 4.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bin3 PF06859.12 KFX85924.1 - 0.15 12.7 3.4 1.2 9.8 3.4 2.6 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) LysM PF01476.20 KFX85928.1 - 5.6e-07 29.5 0.0 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 2 LysM domain PAN_4 PF14295.6 KFX85928.1 - 2.5e-06 27.3 18.6 0.031 14.2 0.5 5.1 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.12 KFX85928.1 - 0.0091 15.8 17.4 0.19 11.6 0.1 4.7 5 0 0 5 5 5 3 PAN-like domain PAN_2 PF08276.11 KFX85928.1 - 0.03 14.4 13.2 1.8 8.7 0.7 3.7 3 0 0 3 3 3 0 PAN-like domain Toxin_28 PF08115.11 KFX85928.1 - 1.2 9.0 5.2 0.87 9.5 1.1 2.6 2 0 0 2 2 2 0 SFI toxin family MANEC PF07502.14 KFX85928.1 - 1.7 9.0 10.2 4 7.8 0.7 3.5 3 0 0 3 3 3 0 MANEC domain SOR_SNZ PF01680.17 KFX85929.1 - 2.3e-10 40.6 0.5 9.2e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 KFX85929.1 - 1e-07 31.6 0.7 1.2e-07 31.3 0.7 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KFX85929.1 - 0.0081 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 KFX85929.1 - 0.0082 15.6 0.1 0.02 14.4 0.1 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 KFX85929.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KFX85929.1 - 0.029 13.8 0.5 0.032 13.6 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.21 KFX85929.1 - 0.045 12.9 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.17 KFX85929.1 - 0.055 12.5 0.3 0.14 11.2 0.2 1.7 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Trp_syntA PF00290.20 KFX85929.1 - 0.085 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain ThiI PF02568.14 KFX85929.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) C1_2 PF03107.16 KFX85930.1 - 0.059 13.7 0.1 0.059 13.7 0.1 2.3 2 0 0 2 2 2 0 C1 domain Mpv17_PMP22 PF04117.12 KFX85931.1 - 2e-09 37.6 1.4 5.1e-09 36.2 1.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF3278 PF11683.8 KFX85931.1 - 0.054 13.6 3.4 0.23 11.5 1.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3278) NADH_oxidored PF08040.11 KFX85931.1 - 0.12 12.0 0.1 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 MNLL subunit BRF1 PF07741.13 KFX85935.1 - 0.031 14.6 3.0 0.13 12.6 2.4 2.5 1 1 0 1 1 1 0 Brf1-like TBP-binding domain ANTH PF07651.16 KFX85942.1 - 1.2e-66 224.5 0.7 1.5e-66 224.2 0.7 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFX85942.1 - 6.6e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TRP PF06011.12 KFX85944.1 - 3.6e-166 553.1 30.9 4.4e-166 552.8 30.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX85944.1 - 9.5e-42 142.7 1.0 2.1e-41 141.5 1.0 1.6 1 0 0 1 1 1 1 ML-like domain Trp_oprn_chp PF09534.10 KFX85944.1 - 0.45 10.3 9.0 2.1 8.1 3.2 3.1 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ac76 PF05814.11 KFX85944.1 - 0.53 10.3 6.3 1.5 8.9 0.6 3.2 3 1 0 3 3 3 0 Orf76 (Ac76) UAF_Rrn10 PF05234.11 KFX85945.1 - 0.00044 20.5 0.0 0.00061 20.0 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 KFX85946.1 - 9.4e-22 76.9 10.4 1.1e-06 29.3 0.4 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX85946.1 - 3.6e-08 33.6 0.2 0.0062 16.8 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX85946.1 - 0.023 13.4 0.1 1.3 7.6 0.0 3.0 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFX85946.1 - 0.029 13.1 0.0 1.7 7.3 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like DUF2457 PF10446.9 KFX85948.1 - 0.054 12.6 3.2 0.067 12.3 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ytp1 PF10355.9 KFX85949.1 - 3.3e-86 289.0 8.1 3.3e-86 289.0 8.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFX85949.1 - 5.1e-28 96.9 4.6 5.1e-28 96.9 4.6 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) K_oxygenase PF13434.6 KFX85949.1 - 3.4e-18 65.9 0.0 1.8e-13 50.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX85949.1 - 1.8e-07 30.7 0.0 0.0053 16.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX85949.1 - 8.5e-06 25.2 0.1 0.037 13.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX85949.1 - 0.00066 19.7 0.0 1.3 9.0 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding KNOX1 PF03790.13 KFX85949.1 - 0.051 13.3 0.5 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 KNOX1 domain GIDA PF01134.22 KFX85949.1 - 0.056 12.5 0.0 0.61 9.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFX85949.1 - 0.069 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KFX85949.1 - 0.14 12.2 0.2 1 9.4 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KFX85949.1 - 3.8 7.8 4.9 1.9 8.7 0.0 3.0 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain AChE_tetra PF08674.10 KFX85949.1 - 5.9 6.7 6.2 0.38 10.5 0.4 2.1 2 0 0 2 2 1 0 Acetylcholinesterase tetramerisation domain ArfGap PF01412.18 KFX85951.1 - 1.3e-35 121.9 0.4 1.6e-35 121.7 0.4 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 KFX85952.1 - 1e-38 132.4 0.1 3e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 TIM21 Xpo1 PF08389.12 KFX85952.1 - 1.4e-29 103.1 2.1 4e-29 101.6 1.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KFX85952.1 - 2.6e-09 36.9 0.1 8e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Coa1 PF08695.10 KFX85952.1 - 3.9e-05 23.4 0.0 0.00017 21.3 0.0 2.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 UME PF08064.13 KFX85952.1 - 0.023 14.6 0.3 0.37 10.7 0.0 2.9 2 0 0 2 2 2 0 UME (NUC010) domain Adaptin_N PF01602.20 KFX85952.1 - 0.07 11.7 0.4 7.9 4.9 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region TPP_enzyme_N PF02776.18 KFX85957.1 - 2.4e-38 131.4 0.0 1.5e-37 128.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFX85957.1 - 2.9e-21 75.8 0.1 2.6e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX85957.1 - 3.5e-11 43.0 0.0 7.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain zf-BED PF02892.15 KFX85960.1 - 6 7.0 7.9 9.3 6.4 0.6 2.6 3 0 0 3 3 3 0 BED zinc finger zf-UDP PF14569.6 KFX85965.1 - 0.053 13.6 0.1 0.053 13.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger BTB PF00651.31 KFX85970.1 - 3.3e-05 24.1 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Lipase_3 PF01764.25 KFX85972.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 KFX85972.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 KFX85972.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX85972.1 - 0.081 13.5 1.1 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Actin PF00022.19 KFX85978.1 - 5.8e-150 499.4 0.0 2.3e-149 497.5 0.0 1.7 1 1 0 1 1 1 1 Actin bZIP_1 PF00170.21 KFX85982.1 - 1.3e-08 34.8 11.3 1.3e-08 34.8 11.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX85982.1 - 0.00027 20.9 10.6 0.00027 20.9 10.6 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 KFX85982.1 - 0.079 12.7 9.3 1.2 8.9 0.9 2.8 2 0 0 2 2 2 0 Septum formation initiator PfkB PF00294.24 KFX85985.1 - 1.6e-06 27.6 0.1 2.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MCM PF00493.23 KFX85986.1 - 4.9e-98 326.7 0.3 7.8e-98 326.0 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFX85986.1 - 9.3e-30 103.1 0.0 1.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFX85986.1 - 8.1e-24 83.9 0.6 1.8e-23 82.7 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFX85986.1 - 9e-12 45.5 0.3 3e-11 43.8 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFX85986.1 - 3.6e-07 29.8 0.0 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFX85986.1 - 0.0017 18.2 0.0 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFX85986.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol_phi PF04931.13 KFX85986.1 - 5.9 4.8 12.4 9.9 4.1 12.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C65 PF10275.9 KFX85990.1 - 9.4e-67 225.0 0.0 1.2e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain IBN_N PF03810.19 KFX85992.1 - 3e-12 46.3 0.0 2.2e-11 43.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFX85992.1 - 0.00027 21.0 1.1 0.0063 16.6 0.1 3.5 3 1 0 3 3 3 1 Exportin 1-like protein DUF3385 PF11865.8 KFX85992.1 - 0.016 15.1 2.5 0.047 13.6 0.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) UME PF08064.13 KFX85992.1 - 0.075 13.0 1.2 0.97 9.4 0.1 3.1 2 1 0 2 2 2 0 UME (NUC010) domain CFEM PF05730.11 KFX85994.1 - 1.9e-11 43.9 13.8 3e-11 43.2 13.8 1.3 1 0 0 1 1 1 1 CFEM domain PEPCK_ATP PF01293.20 KFX85996.1 - 1.1e-119 400.2 0.0 1.3e-119 399.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MRFAP1 PF15155.6 KFX85996.1 - 0.027 15.0 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_33 PF13671.6 KFX85996.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 KFX85997.1 - 1.3e-07 31.6 11.7 3.5e-07 30.2 11.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KFX85997.1 - 0.83 9.4 6.9 0.078 12.7 1.6 2.2 2 0 0 2 2 2 0 Integrin plexin domain TRI12 PF06609.13 KFX86001.1 - 2.5e-10 39.4 11.5 3.3e-10 39.0 11.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX86001.1 - 3.4e-07 29.5 23.4 4.2e-07 29.2 21.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.13 KFX86001.1 - 2.5 7.7 20.2 3.7 7.1 2.4 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF998) AMPK1_CBM PF16561.5 KFX86005.1 - 1.7e-23 82.6 0.5 2.2e-23 82.3 0.5 1.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KFX86005.1 - 0.00099 19.4 0.1 0.00099 19.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KFX86005.1 - 0.0011 19.5 0.3 0.0015 19.1 0.3 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) HCO3_cotransp PF00955.21 KFX86007.1 - 6.3e-07 28.6 0.8 8.7e-07 28.1 0.8 1.2 1 0 0 1 1 1 1 HCO3- transporter family Ferlin_C PF16165.5 KFX86007.1 - 0.15 12.0 2.4 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Ferlin C-terminus RIO1 PF01163.22 KFX86009.1 - 2.9e-05 23.8 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KFX86009.1 - 0.0007 19.6 0.3 0.039 13.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFX86009.1 - 0.0048 16.3 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFX86009.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Acyltransferase PF01553.21 KFX86011.1 - 2.4e-12 46.6 0.0 2.9e-11 43.1 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Tup_N PF08581.10 KFX86012.1 - 0.0011 19.2 4.1 0.11 12.8 0.9 2.4 2 0 0 2 2 2 2 Tup N-terminal DUF3584 PF12128.8 KFX86012.1 - 0.008 13.8 5.9 0.0087 13.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) P4Ha_N PF08336.11 KFX86012.1 - 0.061 13.3 2.3 0.084 12.9 0.4 1.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cnn_1N PF07989.11 KFX86012.1 - 0.07 13.3 0.4 0.07 13.3 0.4 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 KFX86012.1 - 0.073 13.7 7.7 0.14 12.8 1.0 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 KFX86012.1 - 0.085 12.6 2.6 0.33 10.8 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator RmuC PF02646.16 KFX86012.1 - 0.13 11.4 5.7 1.1 8.4 0.7 2.1 1 1 1 2 2 2 0 RmuC family YkyA PF10368.9 KFX86012.1 - 0.26 10.9 6.5 0.47 10.1 6.5 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein FlaC_arch PF05377.11 KFX86012.1 - 0.27 11.7 4.4 3 8.3 0.6 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 KFX86012.1 - 0.27 11.6 11.0 0.099 13.1 1.4 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF745 PF05335.13 KFX86012.1 - 0.28 10.9 10.1 0.82 9.4 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 KFX86012.1 - 0.57 10.3 15.0 0.036 14.2 5.6 2.0 1 1 1 2 2 2 0 Tropomyosin like zf-CpG_bind_C PF12269.8 KFX86012.1 - 0.6 9.8 6.8 0.17 11.6 0.7 2.1 1 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain CENP-F_leu_zip PF10473.9 KFX86012.1 - 0.75 9.8 15.2 5.8 6.9 15.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KFX86012.1 - 1 9.4 4.0 1.8 8.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 KFX86012.1 - 1.1 9.3 6.0 0.53 10.3 1.0 2.3 1 1 1 2 2 2 0 Short coiled-coil protein ZapB PF06005.12 KFX86012.1 - 2.5 8.6 13.0 0.29 11.6 2.1 3.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF4061 PF13270.6 KFX86012.1 - 2.6 8.4 9.1 2.9 8.3 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) JIP_LZII PF16471.5 KFX86012.1 - 2.8 8.2 8.7 0.87 9.8 0.6 2.7 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 KFX86012.1 - 2.9 8.0 11.0 4.9 7.2 9.4 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 KFX86012.1 - 3.1 8.1 10.5 7.4 6.9 1.1 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 KFX86012.1 - 3.1 8.5 13.0 0.91 10.2 3.8 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KFX86012.1 - 4.7 6.5 6.6 3.9 6.7 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 KFX86012.1 - 4.9 7.9 9.0 16 6.3 0.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DivIVA PF05103.13 KFX86012.1 - 8.2 6.5 12.6 2.8 8.1 2.3 2.6 1 1 2 3 3 3 0 DivIVA protein Apolipoprotein PF01442.18 KFX86013.1 - 0.0047 16.8 2.8 0.0047 16.8 2.8 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KFX86013.1 - 0.0073 14.3 1.3 0.0074 14.3 0.2 1.4 2 0 0 2 2 2 1 Prominin TPR_9 PF13371.6 KFX86013.1 - 0.14 12.3 0.1 0.37 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ApoLp-III PF07464.11 KFX86013.1 - 7.6 6.6 9.3 2.5 8.2 2.3 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Latarcin PF10279.9 KFX86016.1 - 3.7 8.0 6.1 1.2 9.6 2.5 2.0 2 0 0 2 2 2 0 Latarcin precursor Fungal_trans PF04082.18 KFX86018.1 - 1.7e-20 73.2 0.0 4.3e-20 71.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX86018.1 - 5.3e-05 23.2 13.1 9.5e-05 22.4 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX86020.1 - 7.4e-31 107.3 29.6 3.7e-30 105.0 30.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily IBR PF01485.21 KFX86024.1 - 0.018 15.2 10.3 0.018 15.2 10.3 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Mt_ATP-synt_D PF05873.12 KFX86030.1 - 1.8e-22 79.9 1.0 2.2e-22 79.6 1.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 KFX86030.1 - 0.0069 14.6 0.8 0.0078 14.4 0.8 1.0 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DUF3544 PF12064.8 KFX86030.1 - 0.039 14.2 0.3 0.05 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 KASH_CCD PF14662.6 KFX86030.1 - 0.077 12.8 4.3 0.69 9.7 1.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH LXG PF04740.12 KFX86030.1 - 0.097 12.4 2.9 0.13 12.0 2.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4515 PF14988.6 KFX86030.1 - 0.14 12.0 6.1 0.52 10.1 1.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4515) RasGAP_C PF03836.15 KFX86030.1 - 0.23 11.6 3.1 0.31 11.2 0.8 2.0 1 1 0 2 2 2 0 RasGAP C-terminus APG6_N PF17675.1 KFX86030.1 - 1.5 9.3 6.4 7.5 7.1 6.4 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region NAC PF01849.18 KFX86031.1 - 1.2e-23 82.8 0.3 3.2e-23 81.5 0.1 1.8 2 0 0 2 2 2 1 NAC domain MoeA_N PF03453.17 KFX86031.1 - 0.017 14.9 0.8 0.026 14.3 0.3 1.7 1 1 1 2 2 2 0 MoeA N-terminal region (domain I and II) GEMIN8 PF15348.6 KFX86031.1 - 0.38 11.0 9.6 0.48 10.7 2.7 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 SelP_N PF04592.14 KFX86031.1 - 0.49 9.7 7.8 0.92 8.9 7.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4637 PF15470.6 KFX86031.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4637) Myc_N PF01056.18 KFX86031.1 - 2.4 8.0 9.6 2.3 8.1 8.9 1.4 1 1 0 1 1 1 0 Myc amino-terminal region FMN_red PF03358.15 KFX86033.1 - 4.3e-09 36.3 0.0 6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX86033.1 - 0.00034 20.4 0.0 0.00044 20.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFX86033.1 - 0.0023 18.2 0.1 0.0056 16.9 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin E1-E2_ATPase PF00122.20 KFX86035.1 - 7.4e-34 116.8 7.3 8.7e-34 116.6 0.0 3.3 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFX86035.1 - 1.4e-17 64.7 0.2 6.1e-17 62.6 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX86035.1 - 6.4e-10 38.6 0.0 1.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX86035.1 - 0.0024 17.7 0.1 0.0062 16.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX86035.1 - 0.0043 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PHO4 PF01384.20 KFX86035.1 - 0.26 10.3 14.7 0.017 14.2 1.0 3.1 2 1 0 2 2 2 0 Phosphate transporter family Glyco_tranf_2_3 PF13641.6 KFX86039.1 - 1.7e-27 96.8 0.1 7.1e-27 94.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX86039.1 - 5.2e-08 32.9 0.0 1.7e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFX86039.1 - 1.6e-06 27.7 0.2 9e-06 25.3 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 PPR_3 PF13812.6 KFX86042.1 - 8.3e-05 22.6 0.1 0.0033 17.5 0.0 2.4 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KFX86042.1 - 0.0015 17.9 0.1 0.077 12.3 0.0 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KFX86042.1 - 0.027 14.7 0.4 0.35 11.1 0.0 2.5 3 0 0 3 3 3 0 PPR repeat family Acyl-CoA_dh_N PF02771.16 KFX86042.1 - 0.14 12.8 0.1 0.32 11.7 0.1 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Nup84_Nup100 PF04121.13 KFX86044.1 - 1.9e-123 413.1 0.6 2.4e-123 412.8 0.6 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Acetyltransf_6 PF13480.7 KFX86044.1 - 0.32 11.1 1.9 0.67 10.1 0.1 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PAS_9 PF13426.7 KFX86045.1 - 4.3e-22 78.3 0.0 9.5e-12 45.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KFX86045.1 - 1.1e-18 67.3 0.0 5.8e-14 52.1 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KFX86045.1 - 1.8e-16 60.1 0.0 1e-07 32.0 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KFX86045.1 - 5.1e-13 49.2 0.0 7.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 KFX86045.1 - 1.3e-07 31.7 0.0 4.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KFX86045.1 - 0.1 12.7 0.0 0.47 10.5 0.0 2.1 2 0 0 2 2 2 0 PAS domain KH_1 PF00013.29 KFX86047.1 - 3.5e-31 106.8 1.5 1.6e-07 31.0 0.0 7.2 8 0 0 8 8 8 6 KH domain Na_H_Exchanger PF00999.21 KFX86048.1 - 4.2e-21 75.2 26.8 3.9e-18 65.4 10.9 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family SAP130_C PF16014.5 KFX86051.1 - 0.4 9.7 3.6 0.46 9.5 3.6 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus COG4 PF08318.12 KFX86056.1 - 5.2e-103 344.6 0.0 7.3e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein ABC_tran PF00005.27 KFX86059.1 - 2e-43 148.2 0.2 2.1e-26 93.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KFX86059.1 - 1.2e-34 120.2 21.8 1.7e-34 119.7 21.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MMR_HSR1 PF01926.23 KFX86059.1 - 1e-06 28.8 1.3 0.017 15.2 0.4 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KFX86059.1 - 5.3e-06 25.8 0.1 0.001 18.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KFX86059.1 - 4.8e-05 23.8 0.1 0.44 10.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KFX86059.1 - 5.7e-05 22.6 2.3 0.17 11.3 0.2 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX86059.1 - 6.5e-05 22.9 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX86059.1 - 0.00084 19.0 3.3 0.48 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX86059.1 - 0.015 15.0 4.1 2.2 8.0 0.4 2.7 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KFX86059.1 - 0.017 15.2 9.7 0.15 12.1 0.6 3.0 3 0 0 3 3 3 0 Dynamin family AAA_22 PF13401.6 KFX86059.1 - 0.022 15.0 1.4 4 7.7 0.1 3.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFX86059.1 - 0.027 14.4 4.0 3 7.7 0.3 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KFX86059.1 - 0.032 14.5 0.7 0.33 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 KFX86059.1 - 0.047 13.6 0.6 9 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 KFX86059.1 - 0.068 13.4 0.1 19 5.5 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 KFX86059.1 - 0.076 12.7 0.2 5.4 6.7 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 KFX86059.1 - 0.091 13.3 7.9 1.7 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KFX86059.1 - 0.1 12.6 6.4 0.17 11.9 0.4 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KFX86059.1 - 0.13 12.8 0.5 16 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KFX86059.1 - 0.16 11.9 0.2 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFX86059.1 - 0.21 11.1 1.0 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KFX86059.1 - 0.35 9.8 2.8 2.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KFX86059.1 - 0.39 10.5 2.8 7.3 6.3 0.4 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3810 PF12725.7 KFX86059.1 - 2.5 7.4 5.0 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) SQS_PSY PF00494.19 KFX86061.1 - 6.1e-37 127.6 0.0 8.7e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4140 PF13600.6 KFX86066.1 - 1.7e-22 79.6 0.0 1.7e-22 79.6 0.0 3.2 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 KFX86066.1 - 1.3e-14 54.4 9.3 2.9e-14 53.3 1.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) His_Phos_1 PF00300.22 KFX86068.1 - 6.8e-27 94.4 0.0 1.6e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VGCC_beta4Aa_N PF12052.8 KFX86068.1 - 0.0057 16.7 1.3 0.0057 16.7 1.3 2.3 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal MCM2_N PF12619.8 KFX86068.1 - 0.51 10.6 8.2 1.2 9.4 8.2 1.6 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Myb_DNA-bind_3 PF12776.7 KFX86070.1 - 0.67 11.0 0.1 0.67 11.0 0.1 3.4 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain SAS4 PF15460.6 KFX86073.1 - 4.7e-32 110.0 0.1 1.2e-31 108.8 0.1 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Bromo_TP_like PF17027.5 KFX86075.1 - 0.047 13.8 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Histone-fold protein MFS_1 PF07690.16 KFX86078.1 - 1.9e-14 53.4 16.7 1.9e-14 53.4 16.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5326 PF17260.2 KFX86078.1 - 0.15 12.3 0.4 0.15 12.3 0.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Ferrochelatase PF00762.19 KFX86079.1 - 3.8e-36 124.8 0.0 4.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF2742 PF10888.8 KFX86079.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) GMC_oxred_C PF05199.13 KFX86081.1 - 4.9e-14 53.1 0.2 1.2e-13 51.8 0.2 1.7 1 1 1 2 2 2 1 GMC oxidoreductase DPBB_1 PF03330.18 KFX86082.1 - 6.4e-06 26.4 0.0 7.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KFX86082.1 - 0.0043 17.2 0.1 0.0051 16.9 0.1 1.0 1 0 0 1 1 1 1 Cerato-platanin BPL_C PF02237.17 KFX86082.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RNA_pol PF00940.19 KFX86083.1 - 5.4e-09 35.4 0.0 5.4e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase BSP_II PF05432.11 KFX86083.1 - 0.022 14.4 8.9 0.027 14.2 8.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 KFX86083.1 - 0.04 14.5 10.1 0.069 13.8 10.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.12 KFX86083.1 - 0.18 10.0 7.9 0.2 9.9 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 KFX86083.1 - 0.22 11.2 7.4 0.35 10.6 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) LAP1C PF05609.12 KFX86083.1 - 0.5 9.4 10.0 0.53 9.3 9.6 1.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NOA36 PF06524.12 KFX86083.1 - 0.61 9.4 6.3 0.75 9.1 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2956 PF11169.8 KFX86083.1 - 2.5 8.3 6.5 0.48 10.6 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RPA43_OB PF17875.1 KFX86083.1 - 7.5 7.2 8.0 1.9 9.1 4.1 1.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Condensation PF00668.20 KFX86084.1 - 1.9e-23 82.9 0.0 1.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Condensation domain DUF4238 PF14022.6 KFX86088.1 - 2.8e-22 79.5 0.0 4.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) SAICAR_synt PF01259.18 KFX86088.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SAICAR synthetase Pkinase PF00069.25 KFX86092.1 - 3.9e-06 26.4 0.0 6.9e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain YrbL-PhoP_reg PF10707.9 KFX86092.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.11 KFX86092.1 - 0.0017 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KFX86092.1 - 0.0032 17.4 0.5 0.0068 16.4 0.4 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX86092.1 - 0.0055 16.1 0.1 0.0079 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX86092.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KFX86092.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 KFX86094.1 - 1.1e-54 181.1 14.3 6.6e-09 36.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KFX86094.1 - 1.6e-19 70.0 8.0 3e-19 69.1 8.0 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KFX86094.1 - 6e-16 58.5 0.0 8.1e-05 22.9 0.0 5.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFX86094.1 - 2e-07 30.6 0.0 0.02 14.2 0.0 4.4 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KFX86094.1 - 5e-06 25.7 0.2 0.8 8.6 0.0 5.2 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX86094.1 - 0.0015 17.3 0.0 1.2 7.7 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Golgin_A5 PF09787.9 KFX86094.1 - 0.0026 17.3 1.7 0.0038 16.8 1.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3037 PF11236.8 KFX86094.1 - 0.005 17.3 0.2 0.0099 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) Nbas_N PF15492.6 KFX86094.1 - 0.0069 15.8 0.0 3.4 6.9 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KFX86094.1 - 0.021 14.7 0.0 12 6.0 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFX86094.1 - 0.068 11.7 0.7 0.76 8.2 0.4 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF3772 PF12607.8 KFX86096.1 - 0.1 12.4 2.2 23 4.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) 2OG-FeII_Oxy_2 PF13532.6 KFX86098.1 - 9.7e-24 84.6 0.0 1.3e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KFX86098.1 - 0.0025 17.9 4.7 0.0052 16.8 4.7 1.5 1 0 0 1 1 1 1 GRF zinc finger NicO PF03824.16 KFX86099.1 - 1.8e-48 165.3 3.5 2.1e-48 165.1 3.5 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein YrvL PF14184.6 KFX86099.1 - 0.085 13.0 3.2 0.2 11.7 3.2 1.6 1 0 0 1 1 1 0 Regulatory protein YrvL LapA_dom PF06305.11 KFX86099.1 - 7.6 6.4 9.6 25 4.8 0.1 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF883 PF05957.13 KFX86102.1 - 0.36 11.4 5.3 0.47 11.1 1.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CsbD PF05532.12 KFX86102.1 - 0.98 9.4 19.9 0.37 10.7 13.2 3.5 2 2 0 2 2 2 0 CsbD-like SPRY PF00622.28 KFX86107.1 - 8.7e-28 96.9 0.2 1.5e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KFX86107.1 - 9.4e-26 90.5 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFX86107.1 - 0.0001 22.1 1.9 0.00014 21.7 0.0 2.3 3 0 0 3 3 3 1 LisH CG-1 PF03859.16 KFX86107.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 CG-1 domain Glyco_hydro_16 PF00722.21 KFX86110.1 - 2.7e-08 33.5 0.0 1.1e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 CENP-B_dimeris PF09026.10 KFX86112.1 - 0.24 11.8 3.6 0.53 10.7 3.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.11 KFX86112.1 - 8.6 6.0 11.7 14 5.3 11.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) K_oxygenase PF13434.6 KFX86117.1 - 2e-106 356.0 0.0 2.6e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFX86117.1 - 6e-08 32.8 0.8 3e-05 24.1 0.0 3.1 2 2 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX86117.1 - 1.5e-07 31.0 0.0 2.3e-05 23.8 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX86117.1 - 8.7e-07 28.4 1.5 4.6e-05 22.8 1.5 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FeS_assembly_P PF01883.19 KFX86120.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein ATP-synt_B PF00430.18 KFX86122.1 - 0.045 13.8 1.5 0.061 13.4 0.7 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Amidase PF01425.21 KFX86124.1 - 2.1e-89 300.6 0.0 2.6e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Amidase NB-ARC PF00931.22 KFX86124.1 - 0.1 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Acetyltransf_3 PF13302.7 KFX86126.1 - 4.8e-14 53.2 0.0 6.8e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX86126.1 - 7.9e-12 45.4 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX86126.1 - 2.9e-05 24.4 0.0 4.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFX86126.1 - 0.0015 18.6 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX86126.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFX86126.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX86126.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein HSP70 PF00012.20 KFX86127.1 - 1.4e-10 40.0 0.4 1.1e-09 37.1 0.2 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KFX86127.1 - 0.019 13.8 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein BBE PF08031.12 KFX86128.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like zf-CCHC PF00098.23 KFX86129.1 - 1.5e-05 24.8 0.8 2.3e-05 24.3 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle Cytidylate_kin PF02224.18 KFX86131.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 KFX86131.1 - 0.00017 21.6 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 KFX86131.1 - 0.00049 20.5 0.0 0.00077 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KFX86131.1 - 0.0008 19.8 0.0 0.0008 19.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SKI PF01202.22 KFX86131.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KFX86131.1 - 0.0027 18.2 0.1 0.0035 17.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX86131.1 - 0.0028 17.6 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KFX86131.1 - 0.0033 17.0 0.1 0.0038 16.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX86131.1 - 0.0035 17.5 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX86131.1 - 0.0035 16.6 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 KFX86131.1 - 0.0038 17.6 0.0 0.0051 17.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KFX86131.1 - 0.005 16.9 0.0 0.0063 16.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KFX86131.1 - 0.0062 16.0 0.0 0.0076 15.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_22 PF13401.6 KFX86131.1 - 0.0089 16.3 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX86131.1 - 0.011 16.1 0.1 0.013 15.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 KFX86131.1 - 0.025 14.7 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_5 PF07728.14 KFX86131.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFX86131.1 - 0.029 13.7 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KFX86131.1 - 0.034 13.6 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KFX86131.1 - 0.035 14.6 0.0 0.041 14.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KFX86131.1 - 0.045 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KFX86131.1 - 0.057 13.3 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 KFX86131.1 - 0.069 13.1 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 KFX86131.1 - 0.07 12.4 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KFX86131.1 - 0.099 12.1 0.1 0.099 12.1 0.1 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFX86131.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain Thermopsin PF05317.11 KFX86131.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Thermopsin APS_kinase PF01583.20 KFX86131.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 KFX86131.1 - 0.12 12.6 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFX86131.1 - 0.15 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KFX86131.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KFX86131.1 - 0.22 10.7 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.11 KFX86131.1 - 0.22 10.7 0.1 0.27 10.5 0.1 1.1 1 0 0 1 1 1 0 ATPase MipZ AAA_PrkA PF08298.11 KFX86131.1 - 0.23 10.3 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain dNK PF01712.19 KFX86131.1 - 0.24 11.2 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase ATPase_2 PF01637.18 KFX86131.1 - 0.26 11.2 0.0 0.31 10.9 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea 2-oxoacid_dh PF00198.23 KFX86132.1 - 4e-56 190.1 0.3 4.5e-56 189.9 0.3 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) ASPRs PF17641.2 KFX86134.1 - 0.064 13.5 1.2 4.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Ancylostoma-associated secreted protein related YniB PF14002.6 KFX86135.1 - 0.051 13.3 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 YniB-like protein Cellulase PF00150.18 KFX86136.1 - 9.7e-13 48.2 0.1 1.6e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FTA2 PF13095.6 KFX86138.1 - 5.3e-05 22.9 0.0 5.5e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFX86138.1 - 0.19 11.0 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain NAD_binding_2 PF03446.15 KFX86142.1 - 2e-12 47.5 0.1 2.1e-12 47.5 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX86142.1 - 0.037 14.6 0.1 0.039 14.5 0.1 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KFX86142.1 - 0.078 12.3 0.1 0.085 12.2 0.1 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX86142.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CwsA PF10814.8 KFX86146.1 - 2.6 8.2 8.6 14 5.9 8.6 1.9 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA PXA PF02194.15 KFX86148.1 - 9e-17 61.6 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 PXA domain DUF1688 PF07958.11 KFX86154.1 - 9.6e-184 611.0 0.0 1.1e-183 610.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Pex14_N PF04695.13 KFX86158.1 - 1.2e-11 45.5 0.2 1.2e-11 45.5 0.2 2.0 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_76 PF03663.14 KFX86161.1 - 5.9e-52 177.4 6.5 6.8e-52 177.2 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX86161.1 - 0.002 17.3 0.8 0.0022 17.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 PDEase_I PF00233.19 KFX86162.1 - 2.7e-62 210.6 0.0 4.4e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Head-tail_con PF12236.8 KFX86162.1 - 0.075 11.5 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DUF1335 PF07056.11 KFX86162.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) HMG_box PF00505.19 KFX86169.1 - 1.3e-24 86.4 0.6 2.4e-24 85.5 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX86169.1 - 2.2e-19 69.8 1.2 2.2e-19 69.8 1.2 1.6 2 0 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 KFX86169.1 - 0.0053 17.3 0.1 0.0053 17.3 0.1 2.2 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KFX86169.1 - 0.021 14.8 0.6 0.021 14.8 0.6 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KFX86169.1 - 0.043 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 KFX86169.1 - 0.19 12.3 4.1 0.072 13.6 1.6 1.6 1 1 1 2 2 2 0 YABBY protein MFS_1 PF07690.16 KFX86172.1 - 8.1e-17 61.2 12.8 1.1e-16 60.7 12.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX86172.1 - 6.9e-16 58.1 8.6 8.1e-16 57.9 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KFX86172.1 - 0.00034 19.3 0.8 0.0004 19.1 0.8 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein PUNUT PF16913.5 KFX86172.1 - 0.0045 16.2 0.4 0.035 13.3 0.1 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport Alginate_lyase PF05426.12 KFX86172.1 - 0.035 13.6 0.1 0.049 13.2 0.1 1.1 1 0 0 1 1 1 0 Alginate lyase DUF3792 PF12670.7 KFX86172.1 - 0.074 13.2 6.1 0.31 11.2 6.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Transgly_assoc PF04226.13 KFX86172.1 - 0.27 11.5 5.0 1.7 8.9 0.5 2.9 2 1 1 3 3 3 0 Transglycosylase associated protein RRM_1 PF00076.22 KFX86176.1 - 4.9e-16 58.3 0.0 7.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF724 PF05266.14 KFX86176.1 - 0.0041 17.0 4.1 0.0058 16.5 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) GAS PF13851.6 KFX86176.1 - 0.0044 16.4 0.8 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 KFX86176.1 - 0.019 15.2 1.5 0.028 14.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 KFX86176.1 - 0.035 14.1 1.4 0.047 13.6 1.4 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD kleA_kleC PF17383.2 KFX86176.1 - 0.056 13.8 2.6 0.096 13.0 2.6 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Gp-FAR-1 PF05823.12 KFX86176.1 - 0.069 13.5 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GPS2_interact PF15784.5 KFX86176.1 - 0.074 13.5 3.5 0.12 12.8 3.5 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RRM_occluded PF16842.5 KFX86176.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFX86176.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DivIC PF04977.15 KFX86176.1 - 0.82 9.5 3.6 1.3 8.9 3.6 1.3 1 0 0 1 1 1 0 Septum formation initiator CBM_1 PF00734.18 KFX86179.1 - 4.2e-10 39.4 2.5 5e-10 39.2 2.5 1.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Aconitase PF00330.20 KFX86181.1 - 1.3e-59 202.4 0.2 1.5e-59 202.2 0.2 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) GPI-anchored PF10342.9 KFX86183.1 - 2.1e-10 41.2 0.0 3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.11 KFX86184.1 - 6.5e-46 156.6 0.0 8.7e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Cyclin CLU_N PF15044.6 KFX86184.1 - 0.044 14.1 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Cyclin_N PF00134.23 KFX86184.1 - 0.054 13.2 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2458 PF10454.9 KFX86185.1 - 4.8e-58 195.6 0.0 7.6e-58 195.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) V-ATPase_C PF03223.15 KFX86187.1 - 6.5e-102 341.7 0.1 7.3e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.20 KFX86188.1 - 7.1e-68 227.5 0.0 8.7e-68 227.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KFX86188.1 - 0.00025 21.2 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX86188.1 - 0.00029 21.4 0.0 0.00038 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFX86188.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KFX86188.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF463 PF04317.12 KFX86188.1 - 0.078 11.9 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 KFX86188.1 - 0.083 13.3 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 KFX86188.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.18 KFX86188.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.12 KFX86188.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 KFX86188.1 - 0.15 11.2 0.1 0.3 10.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit DUF2012 PF09430.10 KFX86193.1 - 2.5e-07 30.8 0.1 4.5e-07 30.0 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KFX86193.1 - 0.047 13.2 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein PAP1 PF08601.10 KFX86194.1 - 2e-67 228.6 2.0 2.5e-67 228.2 2.0 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 DUF3502 PF12010.8 KFX86194.1 - 0.041 14.5 0.1 0.1 13.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3502) DUF155 PF02582.14 KFX86196.1 - 2.9e-53 180.5 0.3 3.8e-53 180.2 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KFX86196.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 ComA PF02679.15 KFX86199.1 - 2e-83 279.6 0.0 2.3e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.8 KFX86199.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) DUF4715 PF15835.5 KFX86202.1 - 0.011 15.8 0.3 0.03 14.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) HOOK PF05622.12 KFX86202.1 - 0.037 12.2 2.7 0.83 7.7 0.5 2.0 2 0 0 2 2 2 0 HOOK protein NPV_P10 PF05531.12 KFX86202.1 - 0.071 13.6 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 KFX86202.1 - 0.1 12.8 2.4 0.14 12.3 2.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.12 KFX86202.1 - 0.13 10.8 1.4 0.14 10.6 1.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aldose_epim PF01263.20 KFX86205.1 - 1e-22 80.8 0.0 1.2e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase S-methyl_trans PF02574.16 KFX86208.1 - 1.8e-49 168.9 0.0 2.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PvlArgDC PF01862.16 KFX86208.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF4643 PF15485.6 KFX86210.1 - 0.045 13.6 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) NIF PF03031.18 KFX86212.1 - 4.5e-28 98.0 0.0 1e-27 96.8 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KFX86212.1 - 2.6e-06 27.3 0.1 5.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KFX86212.1 - 8.5e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KFX86212.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KFX86212.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HisK_sensor PF18698.1 KFX86212.1 - 0.066 13.6 1.8 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Histidine kinase sensor domain Acetyltransf_1 PF00583.25 KFX86214.1 - 3.2e-07 30.6 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX86214.1 - 0.00013 22.3 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX86214.1 - 0.00035 20.5 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Hydrolase_6 PF13344.6 KFX86218.1 - 9.7e-22 77.0 0.0 2.2e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX86218.1 - 6.9e-19 67.7 0.0 2.2e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KFX86218.1 - 0.051 13.9 0.0 5.4 7.2 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KFX86218.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Cyclin_N PF00134.23 KFX86228.1 - 0.00039 20.2 0.1 0.0057 16.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFX86228.1 - 0.0014 18.6 1.4 0.04 14.0 0.4 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KFX86228.1 - 0.088 12.9 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KFX86228.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain Lactamase_B PF00753.27 KFX86229.1 - 1.4e-08 35.0 0.0 2.1e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX86229.1 - 0.00047 19.7 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain P3A PF08727.11 KFX86230.1 - 0.015 14.7 0.5 0.14 11.6 0.1 2.1 1 1 1 2 2 2 0 Poliovirus 3A protein like Vac_ImportDeg PF09783.9 KFX86237.1 - 2.8e-70 235.3 0.6 3.4e-70 235.1 0.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Amidohydro_3 PF07969.11 KFX86238.1 - 1.2e-06 28.3 0.1 1.5e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KFX86238.1 - 0.0032 16.8 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family DUF1749 PF08538.10 KFX86241.1 - 1.4e-95 319.9 0.1 1.8e-95 319.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KFX86241.1 - 0.00024 21.8 0.0 0.0003 21.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX86241.1 - 0.0033 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KFX86241.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LIDHydrolase PF10230.9 KFX86241.1 - 0.043 13.4 0.2 2.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase STI1 PF17830.1 KFX86243.1 - 1.4e-16 60.1 6.7 2.7e-16 59.2 4.9 2.1 2 0 0 2 2 2 1 STI1 domain TPR_1 PF00515.28 KFX86243.1 - 8.2e-14 50.7 0.5 1.8e-06 27.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX86243.1 - 9.4e-08 31.6 0.6 0.0039 17.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX86243.1 - 0.00011 21.8 0.0 0.038 13.7 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 KFX86243.1 - 0.0029 17.7 0.7 0.02 15.1 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX86243.1 - 0.0039 17.9 1.4 0.32 11.9 0.1 3.6 4 1 1 5 5 4 1 Tetratricopeptide repeat Moulting_cycle PF04870.16 KFX86243.1 - 0.005 16.2 0.2 0.0075 15.6 0.2 1.3 1 0 0 1 1 1 1 Moulting cycle NARP1 PF12569.8 KFX86243.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KFX86243.1 - 0.016 15.7 1.1 0.075 13.6 0.0 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFX86243.1 - 0.017 15.3 0.2 0.095 12.9 0.2 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFX86243.1 - 0.03 14.4 0.2 15 5.7 0.0 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KFX86243.1 - 0.06 13.4 0.1 6 7.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX86243.1 - 0.074 13.5 0.1 0.55 10.7 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_92 PF01697.27 KFX86245.1 - 2.3e-07 30.7 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFX86245.1 - 0.00044 20.7 0.2 0.00084 19.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glycoprotein_G PF00802.19 KFX86253.1 - 4.7 6.5 9.3 5 6.4 9.3 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G UPF0020 PF01170.18 KFX86254.1 - 0.00067 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MiAMP1 PF09117.10 KFX86258.1 - 0.032 14.4 0.1 0.046 14.0 0.1 1.3 1 0 0 1 1 1 0 MiAMP1 DUF5117 PF17148.4 KFX86258.1 - 0.042 13.7 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5117) TatD_DNase PF01026.21 KFX86262.1 - 1.6e-34 119.4 0.0 2.3e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase betaPIX_CC PF16523.5 KFX86263.1 - 0.013 15.3 0.5 0.014 15.2 0.5 1.0 1 0 0 1 1 1 0 betaPIX coiled coil TSC22 PF01166.18 KFX86263.1 - 0.021 15.2 0.0 0.026 14.8 0.0 1.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF3574 PF12098.8 KFX86266.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Allexi_40kDa PF05549.11 KFX86266.1 - 0.092 12.2 0.4 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CFEM PF05730.11 KFX86268.1 - 6.1e-11 42.3 13.8 9.3e-11 41.7 13.8 1.3 1 0 0 1 1 1 1 CFEM domain WD40 PF00400.32 KFX86277.1 - 0.00032 21.5 0.0 0.00039 21.2 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat Pex14_N PF04695.13 KFX86280.1 - 4.2e-37 128.2 3.4 4.2e-37 128.2 3.4 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.8 KFX86280.1 - 0.0016 16.1 8.7 0.0022 15.6 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1043 PF06295.12 KFX86280.1 - 0.0046 16.9 0.5 0.01 15.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) WD40_alt PF14077.6 KFX86280.1 - 0.023 14.5 0.7 0.082 12.8 0.2 2.0 1 1 1 2 2 2 0 Alternative WD40 repeat motif CENP-Q PF13094.6 KFX86280.1 - 0.05 13.8 6.1 0.083 13.1 6.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CALCOCO1 PF07888.11 KFX86280.1 - 0.053 12.4 9.2 0.092 11.6 8.8 1.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DCB PF16213.5 KFX86280.1 - 0.22 11.2 1.5 0.28 10.8 1.5 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Prominin PF05478.11 KFX86280.1 - 0.25 9.3 0.1 0.3 9.0 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 KFX86280.1 - 0.91 8.8 5.6 2.6 7.3 5.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1542 PF07564.11 KFX86280.1 - 1.7 8.8 4.8 2.5 8.3 0.1 2.8 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1542) FIVAR PF07554.13 KFX86280.1 - 2.4 9.0 5.3 7 7.5 0.3 3.0 2 2 1 3 3 3 0 FIVAR domain SlyX PF04102.12 KFX86280.1 - 4.9 7.9 9.5 0.24 12.1 0.9 2.9 2 2 0 2 2 2 0 SlyX Methyltransf_25 PF13649.6 KFX86283.1 - 4.5e-08 33.7 0.0 1.8e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86283.1 - 1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX86283.1 - 1.2e-06 28.2 0.0 3.7e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_10 PF05971.12 KFX86283.1 - 0.00016 21.1 0.0 0.00065 19.1 0.0 1.9 2 1 0 2 2 2 1 RNA methyltransferase Methyltransf_23 PF13489.6 KFX86283.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86283.1 - 0.00028 21.5 0.0 0.001 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86283.1 - 0.00048 20.8 0.0 0.0009 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KFX86283.1 - 0.00052 20.5 0.2 0.0088 16.6 0.1 2.9 2 1 0 2 2 2 1 PrmC N-terminal domain N6_Mtase PF02384.16 KFX86283.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 KFX86283.1 - 0.024 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KFX86283.1 - 0.038 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 KFX86283.1 - 0.11 11.9 0.1 0.39 10.1 0.0 1.9 2 1 0 2 2 2 0 RRNA methyltransferase AviRa Glyco_tran_28_C PF04101.16 KFX86290.1 - 2.6e-12 47.1 0.0 4.1e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CDC14 PF08045.11 KFX86292.1 - 1.9e-59 201.1 0.1 2.2e-59 200.9 0.1 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF3736 PF12540.8 KFX86293.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) FAD_binding_6 PF00970.24 KFX86296.1 - 0.00097 19.5 0.0 0.019 15.3 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFX86296.1 - 0.00097 19.8 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4325 PF14213.6 KFX86296.1 - 0.06 13.1 0.0 0.31 10.8 0.0 2.2 3 0 0 3 3 3 0 STAS-like domain of unknown function (DUF4325) NAD_binding_6 PF08030.12 KFX86296.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain LRIF1 PF15741.5 KFX86298.1 - 0.058 11.9 0.1 0.065 11.8 0.1 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 ECH_1 PF00378.20 KFX86300.1 - 5.8e-12 45.5 0.0 6.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX86300.1 - 8.5e-07 28.8 0.1 1.2e-06 28.3 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFX86300.1 - 0.00013 21.9 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 eIF3_subunit PF08597.10 KFX86300.1 - 0.014 15.4 1.9 0.018 15.0 1.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hydrolase_like PF13242.6 KFX86302.1 - 2.9e-13 49.7 0.0 5.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like RRM_1 PF00076.22 KFX86311.1 - 5.2e-39 131.9 0.3 1.1e-18 66.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFX86311.1 - 0.074 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFX86311.1 - 0.094 12.9 0.0 12 6.1 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif DUF3602 PF12223.8 KFX86314.1 - 1.3e-07 32.2 23.5 0.00013 22.5 9.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KFX86314.1 - 5.8 6.5 12.7 1.5 8.4 0.6 2.6 2 1 1 3 3 3 0 GTP1/OBG Abhydrolase_1 PF00561.20 KFX86315.1 - 0.0086 15.8 0.1 0.019 14.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold NAD_binding_11 PF14833.6 KFX86317.1 - 4.3e-30 104.5 0.0 6.2e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KFX86317.1 - 1.1e-22 80.9 0.1 1.7e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M23 PF01551.22 KFX86329.1 - 0.02 15.1 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M23 CLASP_N PF12348.8 KFX86333.1 - 0.002 17.7 0.0 0.0024 17.5 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal IBN_N PF03810.19 KFX86333.1 - 0.016 15.1 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain HATPase_c PF02518.26 KFX86336.1 - 5e-11 43.1 0.0 3.4e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 KFX86336.1 - 0.00032 20.6 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.6 KFX86336.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsK_4TM PF13491.6 KFX86338.1 - 0.00081 19.1 8.9 0.065 12.9 1.5 2.3 1 1 1 2 2 2 2 4TM region of DNA translocase FtsK/SpoIIIE DUF998 PF06197.13 KFX86338.1 - 0.44 10.1 16.6 3.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF1771 PF08590.10 KFX86341.1 - 6.4e-18 64.9 10.2 1.2e-17 64.0 10.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFX86341.1 - 2.7e-10 40.4 0.1 8.2e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 Smr domain Helicase_C PF00271.31 KFX86342.1 - 1.3e-16 60.9 0.1 2e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFX86342.1 - 2.7e-08 33.3 0.0 3.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KFX86342.1 - 0.0042 16.3 0.1 0.018 14.2 0.1 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TK PF00265.18 KFX86342.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase MSA-2c PF12238.8 KFX86343.1 - 0.14 12.1 1.4 0.19 11.7 1.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Tfb5 PF06331.12 KFX86346.1 - 4.3e-24 84.3 0.2 4.7e-24 84.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 SPO22 PF08631.10 KFX86348.1 - 0.041 13.4 0.2 0.22 11.0 0.1 1.8 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF4637 PF15470.6 KFX86350.1 - 3.2 7.5 9.0 5.8 6.6 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pkinase PF00069.25 KFX86353.1 - 2.8e-42 144.9 0.0 3.9e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86353.1 - 3.4e-26 92.1 0.0 5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX86353.1 - 7.6e-05 21.7 0.3 0.00019 20.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFX86353.1 - 0.00037 19.9 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFX86353.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KFX86353.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CheX PF13690.6 KFX86355.1 - 0.046 13.9 0.1 0.048 13.8 0.1 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX DNA_pol_phi PF04931.13 KFX86371.1 - 0.27 9.3 2.3 0.25 9.4 2.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi IL32 PF15225.6 KFX86372.1 - 0.85 10.0 3.6 1.6 9.1 3.6 1.4 1 0 0 1 1 1 0 Interleukin 32 RRM_1 PF00076.22 KFX86382.1 - 1.9e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFX86382.1 - 0.19 11.8 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif SDA1 PF05285.12 KFX86386.1 - 0.13 11.6 17.3 0.17 11.2 17.3 1.1 1 0 0 1 1 1 0 SDA1 SRP-alpha_N PF04086.13 KFX86386.1 - 1.1 9.1 13.4 1.5 8.7 13.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LAP1C PF05609.12 KFX86386.1 - 1.5 7.8 10.0 1.8 7.6 10.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 KFX86386.1 - 2 7.1 9.0 2.7 6.7 9.0 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 KFX86386.1 - 4.2 6.8 9.7 4.8 6.6 9.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 KFX86386.1 - 4.5 5.7 7.6 5.2 5.5 7.6 1.0 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 KFX86386.1 - 4.7 5.2 10.4 5.6 5.0 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec39 PF08314.11 KFX86391.1 - 4.5e-14 51.9 2.2 5.4e-14 51.6 2.2 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 adh_short_C2 PF13561.6 KFX86403.1 - 2.2e-40 138.7 0.1 2.4e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX86403.1 - 1.7e-27 96.2 0.2 2.1e-27 95.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase P_C PF06640.11 KFX86406.1 - 2.3 8.3 8.0 4.1 7.5 8.0 1.4 1 0 0 1 1 1 0 P protein C-terminus zf-HIT PF04438.16 KFX86413.1 - 1.1e-09 38.0 10.0 1.5e-09 37.5 10.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KFX86413.1 - 0.003 17.6 9.5 0.0048 16.9 9.5 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 KFX86413.1 - 0.066 13.4 6.2 0.1 12.7 6.2 1.2 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 KFX86413.1 - 0.1 12.9 3.9 0.17 12.2 3.9 1.3 1 0 0 1 1 1 0 C1 domain DUF2841 PF11001.8 KFX86414.1 - 0.09 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) IFT81_CH PF18383.1 KFX86418.1 - 0.14 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain Aldedh PF00171.22 KFX86422.1 - 8.4e-18 64.1 0.1 8.8e-18 64.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3071 PF11268.8 KFX86422.1 - 0.0083 16.2 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) CHASE6_C PF17150.4 KFX86422.1 - 0.1 13.3 0.1 0.15 12.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Bromo_TP PF07524.13 KFX86422.1 - 0.18 11.8 0.1 0.68 10.0 0.1 1.9 2 0 0 2 2 2 0 Bromodomain associated Peptidase_C48 PF02902.19 KFX86425.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aft1_HRR PF11787.8 KFX86425.1 - 0.058 14.6 0.1 0.09 14.0 0.1 1.4 1 0 0 1 1 1 0 Aft1 HRR domain SWIM PF04434.17 KFX86427.1 - 0.00097 18.7 0.5 0.0017 18.0 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger DnaJ PF00226.31 KFX86430.1 - 9.2e-30 102.6 3.1 1e-29 102.4 3.1 1.0 1 0 0 1 1 1 1 DnaJ domain DUF2686 PF10887.8 KFX86436.1 - 0.19 10.7 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) MULE PF10551.9 KFX86450.1 - 3.4e-20 72.2 1.7 2.7e-19 69.4 0.9 2.1 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 KFX86450.1 - 5.5e-05 22.2 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family YL1 PF05764.13 KFX86452.1 - 0.023 14.8 0.9 0.023 14.8 0.9 2.1 2 0 0 2 2 2 0 YL1 nuclear protein eIF-3c_N PF05470.12 KFX86452.1 - 0.1 10.9 2.9 0.13 10.5 2.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3602 PF12223.8 KFX86454.1 - 4.9e-15 55.9 14.0 3.1e-13 50.1 5.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF4614 PF15391.6 KFX86454.1 - 0.052 13.5 4.3 0.065 13.2 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CytochromB561_N PF09786.9 KFX86454.1 - 0.63 9.0 5.3 0.67 8.9 5.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.9 KFX86454.1 - 4 5.9 4.6 4 5.9 4.6 1.0 1 0 0 1 1 1 0 Macoilin family Condensation PF00668.20 KFX86457.1 - 5.7e-09 35.2 0.0 9.5e-09 34.4 0.0 1.3 1 1 0 1 1 1 1 Condensation domain B12-binding PF02310.19 KFX86457.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.25 KFX86467.1 - 5.1e-50 170.3 0.0 5.9e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86467.1 - 5.5e-18 65.2 0.0 9.5e-18 64.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX86467.1 - 1.6e-07 31.5 0.8 0.0043 17.0 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX86467.1 - 4e-06 26.3 0.0 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFX86467.1 - 1.8e-05 24.2 0.1 2.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX86467.1 - 0.008 15.8 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KFX86467.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFX86467.1 - 0.051 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase NIF PF03031.18 KFX86470.1 - 6.3e-09 35.8 0.0 6.9e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Polyoma_coat PF00718.20 KFX86470.1 - 0.068 12.5 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein RNase_T PF00929.24 KFX86474.1 - 6.4e-06 26.8 0.0 6.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF2967 PF11179.8 KFX86482.1 - 0.26 9.3 5.8 0.28 9.2 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Cwf_Cwc_15 PF04889.12 KFX86487.1 - 0.74 9.5 13.4 0.85 9.3 13.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Adap_comp_sub PF00928.21 KFX86488.1 - 0.00015 21.2 0.0 0.00016 21.2 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF2492 PF10678.9 KFX86489.1 - 0.12 12.7 0.0 0.5 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) TFIIA PF03153.13 KFX86492.1 - 0.057 13.4 13.9 0.062 13.3 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KFX86492.1 - 1.7 8.2 13.6 2.2 7.8 13.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF2418 PF10332.9 KFX86493.1 - 0.19 12.3 0.3 0.45 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) CBP_BcsO PF17037.5 KFX86493.1 - 0.21 11.7 3.2 0.27 11.4 3.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Trehalase PF01204.18 KFX86497.1 - 4.4e-50 171.0 0.1 5.3e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Trehalase Phosphodiest PF01663.22 KFX86497.1 - 0.02 14.5 1.8 0.12 11.9 0.3 2.0 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Acyl-CoA_dh_C PF12806.7 KFX86497.1 - 0.51 10.5 3.8 0.96 9.6 3.8 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like CAF1 PF04857.20 KFX86498.1 - 7.7e-14 51.6 0.0 1.2e-08 34.5 0.0 2.0 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KFX86498.1 - 0.031 14.9 0.2 0.078 13.6 0.0 1.7 2 0 0 2 2 2 0 RFX DNA-binding domain DUF572 PF04502.13 KFX86499.1 - 0.15 11.7 8.5 0.18 11.4 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dus PF01207.17 KFX86505.1 - 0.045 12.8 0.1 0.054 12.6 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) bZIP_1 PF00170.21 KFX86508.1 - 0.00021 21.3 7.4 0.0003 20.8 7.4 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX86508.1 - 0.0011 19.0 7.0 0.0014 18.7 7.0 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFX86508.1 - 0.0028 18.1 1.2 0.0037 17.7 1.2 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor RhoGAP PF00620.27 KFX86509.1 - 1.8e-38 131.7 0.0 2e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF3710 PF12502.8 KFX86517.1 - 0.058 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) FumaraseC_C PF10415.9 KFX86524.1 - 1.1e-23 83.3 0.0 1.3e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Fumarase C C-terminus CdhC PF03598.15 KFX86524.1 - 0.055 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit DUF5538 PF17692.1 KFX86527.1 - 0.061 13.4 4.9 0.085 12.9 4.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5538) CCDC24 PF15669.5 KFX86527.1 - 0.26 11.1 3.2 0.31 10.9 3.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family zf-MIZ PF02891.20 KFX86532.1 - 9e-12 44.6 0.3 1.5e-11 43.8 0.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFX86532.1 - 0.0028 17.4 0.5 0.0098 15.7 0.5 2.0 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CRD PF17979.1 KFX86532.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.8 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Rubredoxin PF00301.20 KFX86532.1 - 0.26 11.3 2.1 0.52 10.4 2.1 1.5 1 0 0 1 1 1 0 Rubredoxin COPI_C PF06957.11 KFX86533.1 - 0.48 9.1 3.1 0.46 9.2 3.1 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pkinase PF00069.25 KFX86537.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86537.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase RNase_PH PF01138.21 KFX86538.1 - 0.038 14.5 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 RCR PF12273.8 KFX86540.1 - 4.4e-13 49.9 19.0 5.1e-13 49.7 19.0 1.0 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TPR_MLP1_2 PF07926.12 KFX86543.1 - 0.0024 17.9 23.0 0.0043 17.1 23.0 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PV-1 PF06637.11 KFX86543.1 - 0.004 16.1 9.1 0.0047 15.8 9.1 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) FapA PF03961.13 KFX86543.1 - 0.0053 15.4 11.1 0.0067 15.1 4.9 2.1 1 1 1 2 2 2 2 Flagellar Assembly Protein A DUF87 PF01935.17 KFX86543.1 - 0.01 16.0 4.2 0.011 15.9 4.2 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Pal1 PF08316.11 KFX86543.1 - 0.02 15.7 1.5 0.031 15.0 1.5 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Seryl_tRNA_N PF02403.22 KFX86543.1 - 0.02 15.1 16.6 0.041 14.1 9.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 KFX86543.1 - 0.062 13.3 25.0 0.18 11.8 2.6 2.4 1 1 1 2 2 2 0 FlxA-like protein GlcNAc_2-epim PF07221.11 KFX86543.1 - 0.066 12.4 2.1 0.079 12.2 2.1 1.2 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF4140 PF13600.6 KFX86543.1 - 0.068 13.6 16.5 1.7 9.2 5.0 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.6 KFX86543.1 - 0.072 13.4 11.8 0.042 14.2 5.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 KFX86543.1 - 0.079 11.8 17.1 0.11 11.4 17.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KFX86543.1 - 0.088 10.7 8.6 0.12 10.3 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_F PF12259.8 KFX86543.1 - 0.15 10.6 7.9 0.19 10.2 7.9 1.0 1 0 0 1 1 1 0 Baculovirus F protein DUF4407 PF14362.6 KFX86543.1 - 0.15 11.4 18.1 0.055 12.8 15.0 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 KFX86543.1 - 0.21 11.1 9.6 0.25 10.9 9.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KFX86543.1 - 0.22 12.0 8.8 0.3 11.5 8.8 1.4 1 0 0 1 1 1 0 AAA domain FtsX_ECD PF18075.1 KFX86543.1 - 0.23 12.1 7.1 0.53 11.0 7.0 1.7 1 1 0 1 1 1 0 FtsX extracellular domain WDCP PF15390.6 KFX86543.1 - 0.29 9.5 8.4 0.33 9.3 8.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Rgp1 PF08737.10 KFX86543.1 - 0.33 10.1 7.7 0.39 9.8 7.7 1.2 1 0 0 1 1 1 0 Rgp1 Prominin PF05478.11 KFX86543.1 - 0.36 8.7 9.0 0.45 8.4 9.0 1.0 1 0 0 1 1 1 0 Prominin CorA PF01544.18 KFX86543.1 - 0.37 10.1 11.3 1 8.6 11.0 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF5320 PF17253.2 KFX86543.1 - 0.4 11.8 14.1 1.4 10.0 1.0 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF5320) Fez1 PF06818.15 KFX86543.1 - 0.41 11.1 17.2 3.4 8.1 17.3 2.0 1 1 0 1 1 1 0 Fez1 Folliculin PF11704.8 KFX86543.1 - 1.2 9.0 5.6 1.7 8.5 5.6 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Jnk-SapK_ap_N PF09744.9 KFX86543.1 - 1.6 8.9 18.2 2.8 8.2 18.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 KFX86543.1 - 2.3 8.3 11.5 68 3.5 11.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KFX86543.1 - 2.5 8.6 12.1 3.5 8.1 0.6 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) zf-CpG_bind_C PF12269.8 KFX86543.1 - 2.7 7.7 8.7 4 7.1 8.7 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain THOC7 PF05615.13 KFX86543.1 - 2.7 8.3 17.1 6.4 7.1 17.1 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 FUSC PF04632.12 KFX86543.1 - 3.1 6.2 6.7 3.7 6.0 6.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1640 PF07798.11 KFX86543.1 - 3.2 7.8 17.1 0.16 12.0 5.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Fmp27_WPPW PF10359.9 KFX86543.1 - 3.4 6.4 14.6 4.8 5.9 14.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.11 KFX86543.1 - 3.7 7.0 10.6 7.1 6.1 10.0 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein PMSI1 PF15322.6 KFX86543.1 - 4.3 6.7 9.5 5.4 6.4 9.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Csm1_N PF18504.1 KFX86543.1 - 4.6 7.7 18.5 8 6.9 0.3 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain Pannexin_like PF12534.8 KFX86543.1 - 5.4 6.0 9.2 7.2 5.6 9.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DivIC PF04977.15 KFX86543.1 - 5.8 6.8 21.1 2 8.3 1.1 3.3 1 1 2 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.11 KFX86543.1 - 7.1 7.3 14.6 1.7 9.2 5.0 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF948 PF06103.11 KFX86543.1 - 7.2 6.9 7.2 2.4 8.5 1.4 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.15 KFX86543.1 - 7.8 7.0 15.7 47 4.4 13.8 2.9 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2937 PF11157.8 KFX86543.1 - 8 6.2 11.1 1.1 9.0 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF724 PF05266.14 KFX86543.1 - 8.9 6.1 15.9 17 5.2 10.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YihI PF04220.12 KFX86553.1 - 0.073 12.8 1.3 0.08 12.7 1.3 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Sugar_tr PF00083.24 KFX86555.1 - 0.0005 19.0 1.1 0.00057 18.9 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Terminase_6C PF17289.2 KFX86567.1 - 0.0033 17.5 0.1 0.0043 17.1 0.1 1.1 1 0 0 1 1 1 1 Terminase RNaseH-like domain DUF848 PF05852.11 KFX86567.1 - 0.0087 16.2 1.3 0.2 11.8 2.4 1.9 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) PspB PF06667.12 KFX86567.1 - 0.62 10.2 2.5 1.2 9.2 1.6 1.9 1 1 1 2 2 2 0 Phage shock protein B NAD_binding_6 PF08030.12 KFX86573.1 - 0.043 14.0 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Lin-8 PF03353.15 KFX86575.1 - 4.8 6.7 8.4 6.1 6.3 8.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4551 PF15087.6 KFX86578.1 - 3 6.6 4.2 3 6.6 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) VWA_3 PF13768.6 KFX86579.1 - 0.00035 20.5 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX86579.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1147 PF06615.11 KFX86579.1 - 0.011 15.7 0.2 0.018 15.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) DUF3435 PF11917.8 KFX86589.1 - 1.3e-13 50.7 0.3 1.5e-13 50.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CobU PF02283.16 KFX86597.1 - 0.021 14.4 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase LTXXQ PF07813.12 KFX86604.1 - 0.091 13.5 0.5 0.13 13.0 0.5 1.2 1 0 0 1 1 1 0 LTXXQ motif family protein Cupin_1 PF00190.22 KFX86607.1 - 3.5e-09 36.4 0.2 3.8e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 Cupin tify PF06200.14 KFX86607.1 - 0.0039 16.5 0.1 0.0089 15.3 0.1 1.6 1 0 0 1 1 1 1 tify domain ANAPC4 PF12896.7 KFX86612.1 - 4.8e-35 120.9 0.0 5.2e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF3435 PF11917.8 KFX86613.1 - 7.2e-08 31.8 0.1 8.1e-08 31.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CAP_N PF01213.19 KFX86614.1 - 0.28 10.6 0.2 0.29 10.6 0.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4266 PF14086.6 KFX86615.1 - 0.0022 18.9 1.9 0.0033 18.3 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4266) DUF5348 PF17295.2 KFX86617.1 - 0.018 15.0 0.4 0.63 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) Abhydrolase_6 PF12697.7 KFX86618.1 - 1.6e-11 45.2 3.1 2.3e-11 44.7 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX86618.1 - 1.1e-07 31.3 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX86618.1 - 0.00049 19.8 0.2 0.00078 19.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFX86618.1 - 0.0024 17.7 0.3 0.004 17.0 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Skp1_POZ PF03931.15 KFX86619.1 - 8.5e-12 45.1 1.1 3.2e-11 43.2 0.5 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain F-box PF00646.33 KFX86619.1 - 0.089 12.7 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 KFX86621.1 - 1.7e-19 70.2 0.8 4e-10 40.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFX86621.1 - 2.2e-14 53.1 0.2 0.00097 19.5 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 KFX86621.1 - 3.1e-12 45.5 0.0 0.0012 19.1 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KFX86621.1 - 6.3e-11 42.6 0.0 4.1e-06 27.2 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX86621.1 - 1.6e-10 41.0 1.2 0.00069 19.9 0.1 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) F-box PF00646.33 KFX86621.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KFX86621.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like Ank_4 PF13637.6 KFX86622.1 - 7.9e-25 86.9 2.0 7.8e-08 32.7 0.2 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX86622.1 - 1.1e-23 83.6 2.9 2.6e-17 63.2 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX86622.1 - 1.6e-19 69.7 11.1 1.2e-08 35.0 0.5 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFX86622.1 - 1.3e-17 63.4 9.3 1.4e-05 25.3 0.2 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KFX86622.1 - 8.3e-16 56.5 3.2 0.00018 21.7 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat IMPDH PF00478.25 KFX86622.1 - 0.034 13.1 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Iso_dh PF00180.20 KFX86624.1 - 4.6e-102 341.7 0.0 5.6e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KFX86624.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 KFX86624.1 - 0.019 15.0 0.0 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 KFX86625.1 - 1.3e-37 129.5 0.0 3.2e-37 128.2 0.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KFX86625.1 - 3.9e-05 23.6 0.7 0.00015 21.8 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 KFX86625.1 - 0.048 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like AKNA PF12443.8 KFX86625.1 - 0.11 13.2 0.1 1.8 9.2 0.0 2.7 3 0 0 3 3 3 0 AT-hook-containing transcription factor Rx_N PF18052.1 KFX86625.1 - 0.15 12.4 2.6 2.8 8.3 0.1 3.6 3 1 0 3 3 3 0 Rx N-terminal domain MIF4G PF02854.19 KFX86626.1 - 8.1e-62 208.6 0.2 1.3e-28 100.2 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KFX86626.1 - 1.1e-43 149.2 6.7 1.1e-43 149.2 6.7 3.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Ion_trans_2 PF07885.16 KFX86627.1 - 5.1e-31 106.5 26.2 2.7e-17 62.5 5.5 3.2 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 KFX86627.1 - 0.022 14.6 6.0 1.4 8.7 2.1 3.5 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain GATA PF00320.27 KFX86628.1 - 3.4e-14 52.2 2.4 6.7e-14 51.2 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger Atg14 PF10186.9 KFX86628.1 - 0.11 11.6 8.3 0.22 10.6 8.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KFX86628.1 - 0.3 11.1 11.5 4.9 7.2 6.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.13 KFX86628.1 - 0.48 10.5 6.7 0.85 9.7 6.7 1.3 1 0 0 1 1 1 0 DivIVA protein UPF0242 PF06785.11 KFX86628.1 - 0.75 9.9 5.4 1.1 9.3 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 KFX86628.1 - 0.88 8.9 4.9 11 5.3 4.9 2.1 1 1 0 1 1 1 0 FAM76 protein Phlebovirus_NSM PF07246.11 KFX86628.1 - 1.2 8.5 4.3 1.8 7.9 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.15 KFX86628.1 - 3.8 7.3 9.5 2.2 8.1 3.9 2.2 2 0 0 2 2 2 0 Septum formation initiator PI3_PI4_kinase PF00454.27 KFX86629.1 - 4e-41 141.5 0.0 5.6e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 KFX86630.1 - 7.8e-71 238.6 0.3 1.6e-70 237.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX86630.1 - 4.6e-13 49.5 0.0 1.6e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX86630.1 - 2.7e-06 27.3 0.0 5.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KFX86630.1 - 3.1e-05 23.8 5.7 6.6e-05 22.8 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFX86630.1 - 0.0017 18.2 7.0 0.0028 17.5 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX86630.1 - 0.0058 16.5 5.8 0.017 15.0 5.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFX86630.1 - 0.027 14.5 0.0 0.069 13.2 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KFX86630.1 - 0.21 11.4 7.5 2 8.4 7.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFX86630.1 - 0.35 10.9 2.1 1.1 9.3 2.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFX86630.1 - 0.69 10.3 3.8 1.6 9.1 3.8 1.7 1 0 0 1 1 1 0 Ring finger domain RNA_pol_I_TF PF04090.12 KFX86631.1 - 1.1e-06 28.3 0.0 0.0001 21.9 0.0 2.3 2 1 0 2 2 2 2 RNA polymerase I specific initiation factor WD40 PF00400.32 KFX86632.1 - 1.2e-15 57.6 6.8 8.9e-05 23.2 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX86632.1 - 2.7e-05 24.4 0.7 2.6 8.4 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KFX86633.1 - 2.4e-27 95.8 0.0 3.9e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KFX86633.1 - 2.4e-22 79.5 0.2 6.7e-22 78.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Yip1 PF04893.17 KFX86633.1 - 1e-13 51.3 8.8 2.2e-13 50.3 8.8 1.5 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 KFX86633.1 - 1.6e-12 47.7 0.1 2.2e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Helicase_C PF00271.31 KFX86633.1 - 6.4e-12 45.8 0.1 2.6e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX86633.1 - 8.8e-07 29.1 0.1 1.9e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KFX86633.1 - 2.2e-06 28.1 0.1 4.5e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like CENP-K PF11802.8 KFX86633.1 - 0.091 12.3 1.0 0.19 11.3 1.0 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DUF1282 PF06930.12 KFX86633.1 - 0.32 10.8 2.8 0.56 10.0 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Na_Ca_ex PF01699.24 KFX86635.1 - 1e-28 100.2 29.7 3.7e-15 56.2 10.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Mob1_phocein PF03637.17 KFX86636.1 - 3.4e-22 79.3 0.0 5.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KFX86636.1 - 0.039 14.2 3.9 0.094 13.0 3.9 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 KFX86637.1 - 2.7e-46 157.4 0.5 4.1e-46 156.8 0.5 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.18 KFX86637.1 - 5.5e-31 107.4 1.2 1.1e-30 106.4 1.2 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RsgA_GTPase PF03193.16 KFX86637.1 - 3.5e-06 27.0 0.1 0.034 14.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFX86637.1 - 0.011 16.1 0.4 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 KFX86637.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.17 KFX86637.1 - 0.02 14.7 0.2 0.056 13.2 0.2 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFX86637.1 - 0.031 14.3 0.0 0.079 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX86637.1 - 0.038 13.5 1.8 0.61 9.6 1.7 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 KFX86637.1 - 0.046 13.7 0.2 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KFX86637.1 - 0.068 12.4 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Septin MeaB PF03308.16 KFX86637.1 - 0.086 11.8 0.5 4.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KFX86637.1 - 0.091 13.1 0.4 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFX86637.1 - 0.099 13.1 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 KFX86641.1 - 4.5e-19 68.9 0.0 6.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86641.1 - 1.7e-14 54.3 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86641.1 - 9.1e-14 51.5 0.1 7.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86641.1 - 1.4e-13 51.3 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86641.1 - 2e-10 41.3 0.0 2.2e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX86641.1 - 0.00062 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFX86641.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFX86641.1 - 0.0023 17.4 0.0 0.0045 16.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX86641.1 - 0.0033 16.8 0.0 0.083 12.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFX86641.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KFX86641.1 - 0.004 17.3 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KFX86641.1 - 0.0064 15.8 0.0 0.034 13.4 0.0 2.2 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KFX86641.1 - 0.02 14.3 0.0 5.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 KFX86641.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain DUF3489 PF11994.8 KFX86641.1 - 0.082 13.0 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Methyltransf_2 PF00891.18 KFX86642.1 - 3.8e-16 59.0 0.0 8.6e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KFX86642.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 KFX86643.1 - 3.4e-67 227.1 3.1 4.4e-67 226.8 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX86643.1 - 1.4e-12 48.3 0.6 2e-07 31.4 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX86643.1 - 0.0001 22.9 0.4 0.36 11.5 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease Glyoxalase PF00903.25 KFX86644.1 - 6.4e-06 26.4 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Esterase_phd PF10503.9 KFX86645.1 - 1.1e-19 70.9 0.1 1.7e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX86645.1 - 5.7e-09 35.8 0.5 8.8e-09 35.1 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family UCR_Fe-S_N PF10399.9 KFX86645.1 - 0.033 13.5 0.7 0.06 12.7 0.7 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YhhN PF07947.14 KFX86646.1 - 2.7e-40 137.9 4.3 5.7e-40 136.9 4.3 1.5 1 1 0 1 1 1 1 YhhN family DHquinase_I PF01487.15 KFX86647.1 - 1.5e-27 97.3 0.0 2.3e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFX86647.1 - 8.2e-17 61.8 0.5 3e-16 60.0 0.1 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KFX86647.1 - 1.9e-16 60.1 0.0 5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFX86647.1 - 4.5e-08 32.7 1.6 1e-07 31.6 1.6 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFX86647.1 - 1.3e-06 28.5 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KFX86647.1 - 0.0079 16.4 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fungal_trans PF04082.18 KFX86648.1 - 4.5e-16 58.7 0.1 7.9e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX86648.1 - 4.9e-07 29.8 13.6 8.7e-07 29.0 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.25 KFX86649.1 - 3.8e-74 249.6 0.0 4.3e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 KFX86650.1 - 1.3e-21 76.7 0.0 2.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFX86650.1 - 5.3e-06 26.1 0.1 1.7e-05 24.5 0.2 1.8 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFX86650.1 - 0.0093 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 KFX86650.1 - 0.1 11.5 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.24 KFX86651.1 - 2.8e-133 445.1 21.2 3.2e-133 444.9 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX86651.1 - 5.2e-20 71.7 28.6 5.2e-20 71.7 28.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 KFX86652.1 - 1.4e-33 116.2 0.1 2e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box-like PF12937.7 KFX86653.1 - 0.00091 19.1 0.2 0.007 16.2 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFX86653.1 - 0.15 12.0 1.9 0.81 9.6 0.4 2.9 2 1 0 2 2 2 0 F-box domain XRCC4 PF06632.12 KFX86655.1 - 4.4e-07 29.1 22.5 1.2e-05 24.3 22.5 2.1 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PPP4R2 PF09184.11 KFX86655.1 - 0.5 9.9 16.5 0.79 9.3 16.5 1.3 1 0 0 1 1 1 0 PPP4R2 PUF PF00806.19 KFX86656.1 - 4.3e-37 123.7 1.9 9.7e-06 25.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 KFX86656.1 - 0.045 14.5 0.0 0.23 12.2 0.0 2.1 2 0 0 2 2 2 0 Regulator of ribonuclease activity B RasGEF PF00617.19 KFX86656.1 - 0.05 13.8 0.0 0.38 10.9 0.0 2.4 1 1 0 2 2 2 0 RasGEF domain Secretin PF00263.21 KFX86656.1 - 0.84 9.3 5.3 2.8 7.5 2.3 2.6 2 1 0 2 2 2 0 Bacterial type II and III secretion system protein MRP-S33 PF08293.11 KFX86657.1 - 1.6e-31 108.4 0.1 1.6e-31 108.4 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 KFX86658.1 - 4.4e-13 49.8 0.3 3.2e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFX86658.1 - 1.2e-09 38.4 0.0 3e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KFX86658.1 - 0.41 11.4 0.0 0.41 11.4 0.0 3.2 2 1 0 2 2 2 0 Double-stranded RNA binding motif Glyco_hydro_43 PF04616.14 KFX86659.1 - 5.9e-71 239.1 0.3 9.5e-71 238.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX86659.1 - 4.3e-12 46.2 0.0 1.3e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain 4HBT PF03061.22 KFX86659.1 - 5.2e-08 33.1 0.1 1.1e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.24 KFX86660.1 - 1.7e-74 251.3 21.5 2e-74 251.1 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX86660.1 - 5.8e-26 91.3 25.6 9.9e-20 70.7 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX86660.1 - 3.2e-06 25.9 2.3 3.2e-06 25.9 2.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MgtC PF02308.16 KFX86660.1 - 2.1 8.7 9.7 0.16 12.4 0.5 3.1 2 1 0 3 3 3 0 MgtC family BC10 PF06726.12 KFX86661.1 - 1.9e-16 60.0 10.6 3.6e-16 59.1 10.6 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Reovirus_L2 PF06016.11 KFX86661.1 - 0.049 10.9 0.0 0.063 10.5 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Ge1_WD40 PF16529.5 KFX86662.1 - 0.00099 18.2 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DZF PF07528.14 KFX86662.1 - 0.031 13.9 2.6 0.035 13.7 0.5 2.2 1 1 1 2 2 2 0 DZF domain DUF1664 PF07889.12 KFX86662.1 - 0.21 11.6 9.5 0.44 10.6 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 KFX86662.1 - 0.47 10.6 6.4 0.051 13.7 0.7 2.4 3 0 0 3 3 3 0 TolA binding protein trimerisation BAR_3 PF16746.5 KFX86662.1 - 1.4 8.5 7.5 0.24 11.1 0.9 2.6 2 1 0 2 2 2 0 BAR domain of APPL family Prefoldin_3 PF13758.6 KFX86663.1 - 2.5e-28 98.0 0.9 7.3e-28 96.5 0.9 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KFX86663.1 - 1.2e-24 86.9 13.7 1.9e-24 86.3 0.2 4.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3835) Noelin-1 PF12308.8 KFX86663.1 - 0.12 12.4 1.0 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein FliJ PF02050.16 KFX86663.1 - 0.2 11.9 4.5 0.33 11.2 0.2 2.9 2 0 0 2 2 2 0 Flagellar FliJ protein NPV_P10 PF05531.12 KFX86663.1 - 0.71 10.4 3.1 18 5.9 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MAT1 PF06391.13 KFX86664.1 - 1.6e-35 122.8 15.4 2.1e-35 122.4 15.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KFX86664.1 - 3e-31 107.1 7.7 4.8e-31 106.4 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX86664.1 - 0.00019 21.2 4.3 0.0004 20.2 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX86664.1 - 0.00034 20.4 4.1 0.00066 19.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX86664.1 - 0.00037 20.3 4.8 0.00057 19.7 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1682 PF07946.14 KFX86664.1 - 0.00065 19.0 2.6 0.00096 18.4 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4483 PF14825.6 KFX86664.1 - 0.0064 16.3 3.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4483) zf-RING_2 PF13639.6 KFX86664.1 - 0.0094 16.3 6.9 0.017 15.5 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX86664.1 - 0.012 15.6 8.1 0.045 13.7 8.3 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX86664.1 - 0.017 15.1 6.8 0.032 14.3 6.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KFX86664.1 - 0.064 12.9 2.3 0.13 11.9 2.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3797 PF12677.7 KFX86664.1 - 0.17 11.8 2.8 0.39 10.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_4 PF14570.6 KFX86664.1 - 0.3 10.9 4.2 1.2 9.0 1.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4192 PF13830.6 KFX86664.1 - 0.37 10.8 7.7 0.64 10.0 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) zf-C3HC4_4 PF15227.6 KFX86664.1 - 0.53 10.5 4.6 1.3 9.2 4.6 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFX86664.1 - 2.2 8.2 8.2 27 4.7 8.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 CS PF04969.16 KFX86665.1 - 1.9e-17 64.0 0.1 1.5e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 CS domain zf-C2H2_3 PF13878.6 KFX86666.1 - 0.078 12.8 4.2 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO SnoaL_4 PF13577.6 KFX86667.1 - 9.5e-06 25.8 0.4 1.5e-05 25.1 0.4 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KFX86667.1 - 0.00045 20.8 0.2 0.00058 20.5 0.2 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFX86667.1 - 0.0096 16.3 0.3 0.024 15.0 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KFX86667.1 - 0.029 14.6 0.6 0.083 13.2 0.0 2.0 2 1 0 2 2 2 0 SnoaL-like domain NmrA PF05368.13 KFX86668.1 - 2.2e-32 112.5 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX86668.1 - 1e-09 38.6 0.0 3.3e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFX86668.1 - 0.012 15.1 0.1 0.033 13.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX86668.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 KFX86669.1 - 7.3e-15 55.8 0.0 1.2e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX86669.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain zf-RING_5 PF14634.6 KFX86671.1 - 5.6e-05 23.0 0.6 0.00053 19.9 0.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX86671.1 - 0.00076 19.5 2.1 0.0029 17.6 2.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFX86671.1 - 0.0033 17.2 1.2 0.023 14.6 0.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFX86671.1 - 0.0075 16.1 1.0 0.017 15.0 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX86671.1 - 0.019 14.8 0.3 0.019 14.8 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX86671.1 - 0.021 14.7 1.4 0.092 12.6 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFX86671.1 - 0.021 14.9 1.2 0.27 11.4 1.1 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 KFX86671.1 - 0.046 13.9 1.6 0.11 12.7 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX86671.1 - 0.049 14.0 1.8 0.22 11.9 0.3 2.3 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 KFX86671.1 - 0.49 10.4 6.5 0.86 9.6 0.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cullin_binding PF03556.15 KFX86672.1 - 3.8e-31 108.0 8.4 5.9e-31 107.4 8.4 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KFX86672.1 - 4e-06 26.5 0.0 7.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.17 KFX86673.1 - 4.6e-23 81.3 0.0 5.8e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 CAF1C_H4-bd PF12265.8 KFX86674.1 - 2.5e-14 53.3 0.1 1.2e-13 51.1 0.0 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFX86674.1 - 7.9e-13 48.7 7.7 3.4e-06 27.7 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX86674.1 - 5.8e-07 29.7 1.2 0.00057 20.1 0.2 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX86674.1 - 0.025 13.2 1.4 0.039 12.6 0.6 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 B-block_TFIIIC PF04182.12 KFX86675.1 - 8.3e-14 51.5 0.0 2.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KFX86675.1 - 0.01 15.7 0.0 0.081 12.8 0.0 2.5 2 0 0 2 2 2 0 MarR family M16C_assoc PF08367.11 KFX86678.1 - 1.5e-73 247.0 0.1 2e-73 246.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KFX86678.1 - 6.6e-24 84.9 0.0 4.7e-23 82.1 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFX86678.1 - 3e-09 37.0 0.1 1.2e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 KFX86679.1 - 3.8e-95 318.6 59.9 6e-95 318.0 59.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Cas6b_C PF17262.2 KFX86679.1 - 4.9 7.3 7.4 0.49 10.5 1.6 2.3 2 0 0 2 2 2 0 Cas6b C-terminal domain TMF_TATA_bd PF12325.8 KFX86679.1 - 7.1 6.9 56.6 3.2 8.0 10.6 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Histone_HNS PF00816.21 KFX86680.1 - 0.036 14.9 2.2 0.14 13.0 2.2 2.0 1 0 0 1 1 1 0 H-NS histone family DUF4120 PF13496.6 KFX86680.1 - 0.14 12.5 0.5 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) NMO PF03060.15 KFX86681.1 - 1.6e-54 185.5 2.3 2e-54 185.2 2.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFX86681.1 - 3.2e-07 29.7 3.3 3.2e-07 29.7 3.3 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFX86681.1 - 0.028 13.5 5.2 0.047 12.7 5.2 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF3254 PF11630.8 KFX86683.1 - 0.23 11.6 0.1 0.65 10.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3254) GAS PF13851.6 KFX86685.1 - 4.6 6.6 20.9 5.8 6.2 2.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA PF00004.29 KFX86686.1 - 3.5e-21 76.0 0.2 2.3e-20 73.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX86686.1 - 6.1e-05 23.5 1.1 0.00034 21.1 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFX86686.1 - 0.00061 19.8 0.0 0.002 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX86686.1 - 0.00061 20.1 0.2 0.015 15.5 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX86686.1 - 0.0049 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX86686.1 - 0.011 16.0 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFX86686.1 - 0.021 15.2 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KFX86686.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFX86686.1 - 0.028 14.5 1.4 0.081 13.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KFX86686.1 - 0.03 14.7 0.3 0.56 10.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.6 KFX86686.1 - 0.03 14.3 0.0 0.36 10.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFX86686.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX86686.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NAAA-beta PF15508.6 KFX86686.1 - 0.1 12.9 0.2 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Sigma54_activ_2 PF14532.6 KFX86686.1 - 0.14 12.3 0.3 1.6 8.9 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFX86686.1 - 1.9 8.2 0.0 1.9 8.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain Acetyltransf_1 PF00583.25 KFX86687.1 - 0.00013 22.1 0.1 0.00019 21.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX86687.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX86687.1 - 0.045 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_N PF08240.12 KFX86688.1 - 3.9e-05 23.5 0.1 0.00038 20.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX86689.1 - 1e-12 48.1 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX86689.1 - 2.7e-06 28.5 0.0 4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hyd_65N_2 PF14498.6 KFX86690.1 - 1.3e-48 165.9 0.1 2e-48 165.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF608 PF04685.13 KFX86690.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region PAH PF02671.21 KFX86691.1 - 4e-11 42.9 1.1 7.9e-11 41.9 0.1 2.1 2 0 0 2 2 2 1 Paired amphipathic helix repeat Helo_like_N PF17111.5 KFX86691.1 - 3.1e-07 30.0 2.4 3.1e-07 30.0 2.4 2.2 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins PI-TkoII_IV PF18714.1 KFX86691.1 - 0.11 11.9 0.2 0.82 9.1 0.1 2.3 2 1 1 3 3 3 0 DNA polymerase II intein Domain IV Rx_N PF18052.1 KFX86691.1 - 0.79 10.0 3.9 12 6.2 0.1 3.4 3 1 0 3 3 3 0 Rx N-terminal domain Dynamin_N PF00350.23 KFX86692.1 - 6.6e-20 71.8 0.0 1.9e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX86692.1 - 8.1e-20 71.2 0.1 1.8e-19 70.1 0.1 1.6 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFX86692.1 - 2.3e-05 24.5 0.0 6.7e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KFX86692.1 - 0.00013 22.1 2.3 0.00085 19.4 0.0 3.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KFX86692.1 - 0.0089 15.6 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 KFX86692.1 - 0.031 14.5 0.1 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 KFX86693.1 - 3.9e-35 121.4 37.0 1.3e-28 100.0 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX86693.1 - 6.9e-13 48.3 6.6 6.9e-13 48.3 6.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 KFX86693.1 - 2.7 6.9 22.1 0.39 9.7 6.2 3.3 2 1 1 3 3 3 0 PUCC protein MatE PF01554.18 KFX86694.1 - 4.3e-54 182.5 25.2 5.1e-28 97.8 9.2 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFX86694.1 - 2.4e-08 34.2 6.0 2.4e-08 34.2 6.0 4.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KFX86695.1 - 8.2e-15 55.0 0.0 9.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family RNase_PH PF01138.21 KFX86696.1 - 1e-05 26.1 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFX86696.1 - 0.099 12.7 0.2 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 SRP-alpha_N PF04086.13 KFX86697.1 - 9e-82 275.3 0.0 1.2e-81 274.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFX86697.1 - 3.3e-51 173.7 0.1 5.5e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFX86697.1 - 3.5e-08 33.5 0.1 1e-07 32.0 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFX86697.1 - 1.9e-06 27.1 0.0 3.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFX86697.1 - 0.0012 18.9 0.1 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KFX86697.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 KFX86697.1 - 0.0044 17.0 0.3 0.032 14.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX86697.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFX86697.1 - 0.0097 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Fer4_NifH PF00142.18 KFX86697.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 KFX86697.1 - 0.025 14.5 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 NTPase CinA PF02464.17 KFX86697.1 - 0.028 14.0 0.2 0.062 12.8 0.2 1.6 1 0 0 1 1 1 0 Competence-damaged protein AAA_33 PF13671.6 KFX86697.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX86697.1 - 0.052 14.1 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KFX86697.1 - 0.052 13.9 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KFX86697.1 - 0.072 13.5 0.3 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 KFX86697.1 - 0.09 11.9 0.1 2.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 KFX86697.1 - 0.092 12.8 0.6 0.52 10.4 0.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 KFX86697.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain YIF1 PF03878.15 KFX86698.1 - 1e-102 342.7 2.2 1.2e-102 342.5 2.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KFX86698.1 - 4.5e-05 23.2 6.1 0.0001 22.1 6.1 1.5 1 0 0 1 1 1 1 Yip1 domain AMP-binding PF00501.28 KFX86699.1 - 2.2e-68 230.8 0.0 2.7e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX86699.1 - 1.1e-06 29.5 0.0 3.4e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 KFX86700.1 - 1.8e-123 412.5 0.0 2.1e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.25 KFX86701.1 - 2.3e-05 24.8 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4692 PF15763.5 KFX86701.1 - 0.79 10.2 7.1 10 6.5 1.5 2.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) GATase_6 PF13522.6 KFX86702.1 - 2.3e-13 50.5 0.0 5.5e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFX86702.1 - 6.2e-11 42.3 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFX86702.1 - 3.1e-08 33.3 0.0 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFX86702.1 - 0.0031 16.5 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TFIIS_C PF01096.18 KFX86703.1 - 9.1e-20 70.2 3.1 9.1e-20 70.2 3.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFX86703.1 - 0.0098 15.8 13.8 0.016 15.1 0.1 3.4 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit zf-RING_12 PF17976.1 KFX86703.1 - 9.3 6.6 8.0 0.81 10.0 0.9 2.7 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 KFX86704.1 - 3.8e-09 37.0 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX86704.1 - 7.8e-08 32.0 0.1 0.0028 18.0 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFX86704.1 - 5e-07 30.2 0.0 3.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX86704.1 - 1.4e-06 28.5 0.0 0.076 13.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SIL1 PF16782.5 KFX86704.1 - 0.013 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Ank_5 PF13857.6 KFX86704.1 - 0.041 14.2 0.2 2.2 8.7 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) rve PF00665.26 KFX86706.1 - 5.9e-15 55.5 0.0 9.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFX86706.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Endotoxin_N PF03945.14 KFX86706.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain rve_3 PF13683.6 KFX86706.1 - 0.04 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Trypan_PARP PF05887.11 KFX86707.1 - 0.0084 16.1 8.0 0.019 15.0 8.0 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3391 PF11871.8 KFX86707.1 - 1 9.9 6.2 3.5 8.2 6.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) YflT PF11181.8 KFX86708.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Heat induced stress protein YflT Hep_59 PF07052.11 KFX86709.1 - 0.041 14.6 0.7 0.3 11.9 0.7 2.3 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF4692 PF15763.5 KFX86709.1 - 4.1 7.8 4.9 6.7 7.2 4.9 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Beta-lactamase PF00144.24 KFX86711.1 - 4.3e-46 157.7 0.1 1.4e-45 156.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX86711.1 - 0.0008 18.9 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_3_C PF01915.22 KFX86712.1 - 1.7e-50 171.8 0.1 2.7e-50 171.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX86712.1 - 3.7e-42 144.8 0.0 5.8e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX86712.1 - 2.9e-12 46.5 0.0 6.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain AAA PF00004.29 KFX86713.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX86713.1 - 1.3e-11 44.3 0.2 2.5e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFX86713.1 - 1.8e-10 40.4 0.6 3.3e-10 39.6 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KFX86713.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFX86713.1 - 4.6e-06 26.9 0.2 0.0057 16.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX86713.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFX86713.1 - 4.6e-05 23.4 0.1 0.00017 21.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX86713.1 - 0.00026 20.8 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX86713.1 - 0.00029 21.3 0.2 0.0074 16.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFX86713.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KFX86713.1 - 0.0013 18.3 0.7 0.007 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KFX86713.1 - 0.0024 18.1 0.3 0.0075 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX86713.1 - 0.0026 17.9 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX86713.1 - 0.012 15.6 0.2 0.63 9.9 0.1 2.6 2 1 1 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KFX86713.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KFX86713.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFX86713.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFX86713.1 - 0.032 13.6 0.1 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 KFX86713.1 - 0.039 13.1 1.6 0.07 12.3 0.1 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 KFX86713.1 - 0.05 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KFX86713.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KFX86713.1 - 0.07 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KFX86713.1 - 0.11 12.1 1.3 0.55 9.8 0.4 2.4 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX86713.1 - 0.15 12.6 0.5 1 9.9 0.5 2.4 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFX86713.1 - 0.16 11.1 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFX86713.1 - 0.18 11.3 0.9 0.5 9.8 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KFX86713.1 - 0.25 11.0 2.4 0.3 10.8 0.3 2.2 2 1 0 2 2 2 0 AAA domain UQ_con PF00179.26 KFX86714.1 - 2.9e-42 143.6 0.0 4.1e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KFX86714.1 - 1.4e-07 31.2 0.1 2.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 KFX86714.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UBA PF00627.31 KFX86714.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Methyltransf_24 PF13578.6 KFX86715.1 - 0.0024 18.9 0.0 0.005 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MFS_5 PF05631.14 KFX86716.1 - 3.2e-75 253.2 11.1 4.4e-75 252.8 11.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KFX86716.1 - 1.9e-21 76.4 29.3 1.3e-20 73.6 30.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX86716.1 - 5.7e-05 22.1 5.2 0.0019 17.1 0.1 2.6 2 1 0 2 2 2 2 MFS_1 like family Gaa1 PF04114.14 KFX86716.1 - 0.0014 17.8 2.8 0.0028 16.8 2.8 1.4 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF63 PF01889.17 KFX86716.1 - 0.28 11.3 8.6 0.041 14.1 3.2 2.0 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 BAR PF03114.18 KFX86717.1 - 4.5e-64 216.4 3.8 5.5e-64 216.1 3.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KFX86717.1 - 0.022 15.5 0.0 0.14 13.0 0.0 2.3 2 1 0 2 2 2 0 CP12 domain SVIP PF15811.5 KFX86717.1 - 0.17 12.4 0.5 0.17 12.4 0.5 2.2 3 1 0 3 3 3 0 Small VCP/p97-interacting protein DUF948 PF06103.11 KFX86718.1 - 0.048 13.9 11.3 0.25 11.6 0.5 4.0 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) CcmH PF03918.14 KFX86718.1 - 1.9 7.8 9.7 1.5 8.1 6.8 2.4 1 1 1 2 2 2 0 Cytochrome C biogenesis protein DUF3429 PF11911.8 KFX86719.1 - 0.021 15.1 0.2 0.036 14.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) TRIQK PF15168.6 KFX86719.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family ABC_tran_Xtn PF12848.7 KFX86719.1 - 0.21 11.7 2.1 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter eIF-5a PF01287.20 KFX86720.1 - 3.8e-06 26.9 0.0 1.5e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PRP38 PF03371.15 KFX86721.1 - 2.4e-55 187.1 0.0 2.9e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 PRP38 family OATP PF03137.20 KFX86722.1 - 0.23 9.7 0.1 0.32 9.2 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_C1_2 PF03051.15 KFX86723.1 - 1.4e-53 182.2 0.2 1.6e-53 182.1 0.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFX86723.1 - 0.00013 22.1 0.1 0.00014 22.0 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_M48 PF01435.18 KFX86725.1 - 1.2e-35 123.0 0.0 3.4e-34 118.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family M48 Neogenin_C PF06583.12 KFX86727.1 - 0.64 9.8 4.8 0.14 12.0 1.2 1.6 2 0 0 2 2 2 0 Neogenin C-terminus Ribosomal_L16 PF00252.18 KFX86728.1 - 3.5e-45 153.2 0.1 5.1e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FUSC PF04632.12 KFX86729.1 - 0.19 10.2 5.6 0.33 9.4 5.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3919 PF13057.6 KFX86729.1 - 0.99 8.9 4.5 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Cyt-b5 PF00173.28 KFX86730.1 - 8.9e-21 73.8 0.1 1e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ceramidase PF05875.12 KFX86731.1 - 5.6e-92 307.9 6.2 6.9e-92 307.6 6.2 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_transf_64 PF09258.10 KFX86731.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain HIGH_NTase1_ass PF16581.5 KFX86734.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TetR_C_33 PF13305.6 KFX86736.1 - 0.24 12.1 3.2 2.4 8.9 3.2 2.2 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Abhydrolase_6 PF12697.7 KFX86737.1 - 3.5e-16 60.5 0.0 4.6e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX86737.1 - 6.6e-16 58.7 0.1 1.6e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX86737.1 - 1.3e-10 41.0 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFX86737.1 - 5.9e-06 25.5 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KFX86737.1 - 0.0029 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KFX86737.1 - 0.0042 15.8 0.0 0.014 14.1 0.0 2.0 2 1 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 KFX86737.1 - 0.16 11.8 0.1 0.75 9.5 0.0 2.1 3 0 0 3 3 3 0 Alpha/beta hydrolase family Acyl_transf_1 PF00698.21 KFX86737.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain YopD PF05844.12 KFX86737.1 - 0.25 10.3 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 YopD protein FAD_binding_4 PF01565.23 KFX86738.1 - 1.4e-21 76.7 2.2 2.6e-21 75.8 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX86738.1 - 3.5e-11 43.0 0.0 8.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DSPc PF00782.20 KFX86739.1 - 1.3e-19 70.4 0.0 2.8e-19 69.2 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX86739.1 - 0.0063 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BacA PF02673.18 KFX86739.1 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA Abhydrolase_3 PF07859.13 KFX86741.1 - 1.5e-15 57.6 0.1 7.2e-15 55.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX86741.1 - 1.2e-10 41.3 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KFX86741.1 - 5e-09 35.3 0.1 0.0031 16.2 0.0 2.7 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KFX86741.1 - 5.7e-09 35.3 0.0 8.8e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFX86741.1 - 3.1e-08 33.2 0.0 7.5e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFX86741.1 - 9.3e-08 31.4 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 KFX86741.1 - 1.8e-05 24.5 0.0 4.5e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 KFX86741.1 - 2.8e-05 23.8 0.0 0.0032 17.1 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFX86741.1 - 5.7e-05 23.8 0.4 9.9e-05 23.0 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KFX86741.1 - 6.3e-05 22.0 0.1 0.00041 19.4 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.20 KFX86741.1 - 0.036 13.7 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFX86741.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Say1_Mug180 PF10340.9 KFX86741.1 - 0.26 10.1 0.3 0.7 8.7 0.3 1.6 1 1 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KFX86742.1 - 5.3e-36 124.5 0.0 8.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX86742.1 - 0.0012 17.8 0.0 0.0055 15.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 KFX86742.1 - 0.0025 17.4 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KFX86742.1 - 0.05 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.8 KFX86742.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KFX86743.1 - 1.2e-42 146.2 0.0 1.4e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX86743.1 - 1.3e-10 40.8 0.1 2.7e-10 39.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 KFX86743.1 - 0.018 15.2 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 KFX86743.1 - 0.029 13.9 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KFX86743.1 - 0.059 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 KFX86743.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.8 KFX86743.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Say1_Mug180 PF10340.9 KFX86743.1 - 0.27 10.0 0.0 0.54 9.1 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase Aldolase_II PF00596.21 KFX86744.1 - 2e-10 40.9 0.1 2.7e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short_C2 PF13561.6 KFX86746.1 - 4.7e-54 183.4 2.4 2.3e-53 181.2 2.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX86746.1 - 6.4e-35 120.4 2.0 2.3e-34 118.6 2.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX86746.1 - 1.3e-06 28.4 0.6 1.9e-06 27.9 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFX86746.1 - 2.7e-06 27.0 0.5 0.01 15.3 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX86746.1 - 0.011 15.1 0.1 0.25 10.7 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KFX86748.1 - 2.3e-12 46.5 3.5 3.9e-12 45.8 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX86748.1 - 2.2e-06 27.6 10.6 5.1e-06 26.5 10.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_A PF01968.18 KFX86749.1 - 3.7e-22 78.9 0.2 4.9e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FAD_binding_3 PF01494.19 KFX86750.1 - 7.5e-21 74.7 0.0 2.6e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX86750.1 - 0.00038 19.8 0.5 0.19 10.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX86750.1 - 0.0027 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX86750.1 - 0.0078 15.5 0.5 1.3 8.2 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX86750.1 - 0.024 14.2 0.2 0.049 13.2 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX86750.1 - 0.024 13.7 0.3 0.15 11.1 0.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX86750.1 - 0.089 11.9 0.3 0.19 10.7 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFX86750.1 - 0.2 10.5 0.1 14 4.3 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase ADH_N PF08240.12 KFX86751.1 - 2.5e-28 98.1 0.5 2.5e-28 98.1 0.5 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX86751.1 - 2.9e-26 92.0 0.2 5.2e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX86751.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KFX86751.1 - 0.0081 15.6 0.4 0.015 14.7 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KFX86751.1 - 0.054 12.9 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACP_syn_III_C PF08541.10 KFX86751.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MMR_HSR1 PF01926.23 KFX86752.1 - 2.7e-05 24.2 0.2 0.00019 21.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFX86752.1 - 3.7e-05 23.8 0.0 0.0013 18.9 0.0 2.9 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KFX86752.1 - 0.00022 21.2 0.0 0.00076 19.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 KFX86752.1 - 0.0025 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KFX86752.1 - 0.0032 16.8 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 KFX86752.1 - 0.013 16.0 0.0 0.045 14.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KFX86752.1 - 0.014 15.6 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KFX86752.1 - 0.03 14.7 0.8 0.11 12.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 KFX86752.1 - 0.043 13.1 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 AIG1 family KAP_NTPase PF07693.14 KFX86752.1 - 0.046 13.0 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.6 KFX86752.1 - 0.12 12.9 0.3 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain S1 PF00575.23 KFX86754.1 - 1.5e-72 239.9 36.5 1.2e-13 51.2 1.4 13.2 13 0 0 13 13 13 10 S1 RNA binding domain Suf PF05843.14 KFX86754.1 - 1.3e-06 28.7 6.2 0.00036 20.6 0.0 3.7 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFX86754.1 - 0.00024 21.7 0.1 44 5.3 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat S1_2 PF13509.6 KFX86754.1 - 0.00058 19.9 0.1 5.6 7.1 0.0 4.4 3 0 0 3 3 3 2 S1 domain RNase_II_C_S1 PF18614.1 KFX86754.1 - 0.0006 19.7 5.7 21 5.1 0.0 6.4 6 0 0 6 6 6 0 RNase II-type exonuclease C-terminal S1 domain PCB_OB PF17092.5 KFX86754.1 - 0.0011 19.7 8.0 1.9 9.3 0.0 7.4 8 1 0 9 9 9 1 Penicillin-binding protein OB-like domain TPR_19 PF14559.6 KFX86754.1 - 0.0013 19.2 0.0 8 7.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFX86754.1 - 0.0022 17.2 0.6 0.055 12.6 0.8 2.4 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 KFX86754.1 - 0.062 14.0 0.0 9.6 6.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ProQ_C PF17516.2 KFX86754.1 - 1 8.9 6.0 1.6 8.2 0.1 4.3 5 0 0 5 5 5 0 ProQ C-terminal domain DOT1 PF08123.13 KFX86755.1 - 4.9e-72 241.8 0.1 7.3e-72 241.2 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 ASFV_J13L PF05568.11 KFX86755.1 - 5.9 6.6 6.8 13 5.5 0.1 2.6 2 0 0 2 2 2 0 African swine fever virus J13L protein ATG16 PF08614.11 KFX86756.1 - 1.6e-51 175.4 17.1 2.2e-51 174.9 17.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KFX86756.1 - 0.11 12.6 11.8 1.2 9.2 11.8 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 KFX86756.1 - 0.58 10.3 0.1 0.58 10.3 0.1 3.2 2 1 0 3 3 3 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KFX86756.1 - 1.1 9.5 12.8 3.1 8.0 9.7 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DHR10 PF18595.1 KFX86756.1 - 3.2 7.8 21.6 0.42 10.7 3.0 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Ras PF00071.22 KFX86757.1 - 1.4e-56 190.5 0.1 1.7e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX86757.1 - 6.2e-32 110.3 0.0 8.7e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX86757.1 - 9.9e-13 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX86757.1 - 9.1e-08 32.2 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX86757.1 - 2.1e-06 27.2 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX86757.1 - 1.2e-05 24.9 0.0 0.00058 19.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX86757.1 - 7.3e-05 22.7 0.1 0.0048 16.8 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KFX86757.1 - 0.0035 17.1 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFX86757.1 - 0.0065 16.1 0.0 0.029 14.0 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KFX86757.1 - 0.007 16.2 0.3 0.19 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KFX86757.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX86757.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFX86757.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFX86757.1 - 0.01 15.1 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFX86757.1 - 0.016 15.6 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFX86757.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX86757.1 - 0.026 14.0 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydro_75 PF07335.11 KFX86757.1 - 0.073 13.3 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATPase_2 PF01637.18 KFX86757.1 - 0.08 12.8 0.5 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFX86757.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFX86757.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KFX86757.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 KFX86757.1 - 0.16 11.5 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KFX86757.1 - 0.16 11.1 0.1 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF3955 PF13127.6 KFX86758.1 - 7.9e-10 38.4 2.8 5.9e-09 35.6 2.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) EamA PF00892.20 KFX86758.1 - 1.6e-09 38.1 41.6 3e-06 27.5 9.3 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KFX86758.1 - 1.1e-07 31.7 14.9 2.4e-07 30.6 11.9 2.6 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 KFX86758.1 - 1.2e-05 24.7 3.5 1.2e-05 24.7 3.5 2.6 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport Spb1_C PF07780.12 KFX86759.1 - 2.3e-85 285.5 8.8 2.3e-85 285.5 8.8 2.9 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KFX86759.1 - 1e-55 188.6 0.1 2e-55 187.7 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KFX86759.1 - 2.4e-50 170.6 6.9 2.4e-50 170.6 6.9 4.3 3 1 0 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KFX86759.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFX86759.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3915 PF13054.6 KFX86759.1 - 0.1 12.6 0.4 0.33 10.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF4519 PF15012.6 KFX86759.1 - 3.4 7.9 7.7 16 5.8 7.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Sugar_tr PF00083.24 KFX86762.1 - 4.3e-68 230.2 22.7 5e-68 230.0 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX86762.1 - 1.2e-06 27.7 38.6 2.1e-06 26.9 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fmp27 PF10344.9 KFX86763.1 - 2.8e-207 690.8 0.0 4.3e-207 690.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KFX86763.1 - 8.8e-202 671.2 5.8 8.8e-202 671.2 5.8 3.6 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KFX86763.1 - 1.5e-179 597.9 0.1 2.7e-179 597.1 0.1 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KFX86763.1 - 3.2e-57 192.8 0.1 8.3e-57 191.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KFX86763.1 - 1.2e-55 187.9 0.0 2.8e-55 186.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KFX86763.1 - 1.4e-33 115.7 0.2 9.5e-33 113.0 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 KFX86763.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain ELO PF01151.18 KFX86764.1 - 6.4e-63 212.6 20.7 7.6e-63 212.4 20.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L4 PF00573.22 KFX86765.1 - 9.1e-35 120.1 0.3 1.3e-34 119.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFX86765.1 - 2.9e-28 97.7 1.0 4.6e-28 97.1 0.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain HDA2-3 PF11496.8 KFX86766.1 - 1.1e-13 51.0 0.2 1.1e-11 44.5 0.0 3.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4196 PF13846.6 KFX86766.1 - 0.0023 18.1 1.1 0.012 15.9 1.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4196) AT_hook PF02178.19 KFX86766.1 - 0.21 11.5 24.2 0.032 14.1 3.0 3.7 3 0 0 3 3 3 0 AT hook motif Pox_A_type_inc PF04508.12 KFX86766.1 - 1.7 8.7 6.7 6.4 6.8 1.2 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat COX5A PF02284.16 KFX86767.1 - 1e-40 137.9 0.6 1.5e-40 137.4 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ER_lumen_recept PF00810.18 KFX86769.1 - 7.3e-54 182.6 10.8 7.3e-54 182.6 10.8 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF485 PF04341.12 KFX86769.1 - 0.0045 16.9 0.2 0.0045 16.9 0.2 3.0 2 1 1 3 3 3 1 Protein of unknown function, DUF485 PQ-loop PF04193.14 KFX86769.1 - 0.99 9.2 13.2 1.9 8.3 0.2 3.9 4 0 0 4 4 4 0 PQ loop repeat LSM14 PF12701.7 KFX86770.1 - 2.7e-30 104.3 0.1 4.2e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFX86770.1 - 3.8e-15 56.6 7.6 2.3e-14 54.1 7.6 2.4 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KFX86770.1 - 3.4e-06 27.1 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF5572 PF17733.1 KFX86771.1 - 5.9e-20 70.8 0.1 1e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Baculo_PEP_C PF04513.12 KFX86772.1 - 5.6e-05 23.2 23.0 0.14 12.2 0.0 6.5 3 3 0 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus Sugarporin_N PF11471.8 KFX86772.1 - 0.0027 17.6 3.7 0.0065 16.4 0.1 3.5 3 0 0 3 3 3 1 Maltoporin periplasmic N-terminal extension VPS28 PF03997.12 KFX86772.1 - 0.016 14.9 5.9 0.075 12.7 0.2 2.8 2 0 0 2 2 2 0 VPS28 protein DUF1664 PF07889.12 KFX86772.1 - 0.024 14.7 36.4 0.21 11.6 1.9 7.4 7 2 1 8 8 8 0 Protein of unknown function (DUF1664) YojJ PF10372.9 KFX86772.1 - 0.034 14.2 8.3 2.1 8.5 0.0 5.5 5 0 0 5 5 5 0 Bacterial membrane-spanning protein N-terminus DUF5076 PF16826.5 KFX86772.1 - 0.042 13.8 0.2 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) Spectrin PF00435.21 KFX86772.1 - 0.066 13.7 0.4 0.066 13.7 0.4 7.2 5 3 2 8 8 8 0 Spectrin repeat HALZ PF02183.18 KFX86772.1 - 1.1 9.5 7.7 9.3 6.6 0.7 4.9 6 0 0 6 6 6 0 Homeobox associated leucine zipper Trns_repr_metal PF02583.17 KFX86772.1 - 4.7 7.7 15.2 5.8 7.4 0.2 4.6 5 0 0 5 5 5 0 Metal-sensitive transcriptional repressor TIP49 PF06068.13 KFX86773.1 - 3.4e-153 510.0 2.7 4.3e-153 509.6 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFX86773.1 - 1.1e-20 73.6 0.5 3.5e-20 71.9 0.2 2.2 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KFX86773.1 - 5.6e-09 35.9 0.3 0.00015 21.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KFX86773.1 - 2e-08 34.7 0.3 0.00014 22.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KFX86773.1 - 6.3e-07 29.0 1.1 1.3e-06 27.9 1.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KFX86773.1 - 2.5e-05 24.7 0.1 7.6e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KFX86773.1 - 0.00013 21.4 0.8 0.0042 16.5 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFX86773.1 - 0.0022 18.3 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX86773.1 - 0.0038 17.2 0.4 0.97 9.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KFX86773.1 - 0.018 15.4 2.7 0.48 10.8 2.7 2.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFX86773.1 - 0.029 14.1 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFX86773.1 - 0.077 12.6 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFX86773.1 - 0.11 12.2 2.0 0.7 9.6 2.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX86773.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Chromo PF00385.24 KFX86774.1 - 6.7e-10 38.7 0.4 1.4e-09 37.7 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mago-bind PF09282.10 KFX86774.1 - 3.7e-05 23.5 0.5 9.4e-05 22.2 0.5 1.7 1 0 0 1 1 1 1 Mago binding Ras PF00071.22 KFX86775.1 - 3.6e-63 212.0 0.2 4.2e-63 211.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX86775.1 - 2.1e-35 121.5 0.2 3e-35 121.1 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX86775.1 - 9.6e-13 48.0 0.1 1.2e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX86775.1 - 8.8e-08 32.2 0.1 1.3e-07 31.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX86775.1 - 5.8e-05 23.1 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFX86775.1 - 0.00069 19.2 0.1 0.0027 17.3 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFX86775.1 - 0.0008 18.8 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KFX86775.1 - 0.003 17.8 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFX86775.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KFX86775.1 - 0.015 15.3 0.1 0.039 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX86775.1 - 0.021 15.2 0.1 0.032 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFX86775.1 - 0.027 14.2 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX86775.1 - 0.028 14.9 0.1 0.037 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KFX86775.1 - 0.041 13.3 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KFX86775.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SpoIIID PF12116.8 KFX86775.1 - 0.096 12.8 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_21 PF13304.6 KFX86775.1 - 0.12 12.2 0.5 0.14 11.9 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFX86775.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region F-box-like PF12937.7 KFX86776.1 - 8e-05 22.4 1.3 0.00012 21.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like WLM PF08325.10 KFX86777.1 - 7.4e-50 169.7 0.0 1.2e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KFX86777.1 - 0.013 15.5 2.2 0.016 15.3 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 SprT-like PF10263.9 KFX86777.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 SprT-like family DUF5323 PF17257.2 KFX86777.1 - 0.16 11.8 0.9 0.35 10.8 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5323) ACBP PF00887.19 KFX86778.1 - 1.5e-24 86.0 0.0 6.5e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein PRT_C PF08372.10 KFX86778.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal SAPS PF04499.15 KFX86778.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 KFX86778.1 - 0.22 10.9 1.6 12 5.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GFA PF04828.14 KFX86779.1 - 8.9e-23 80.5 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-FCS PF06467.14 KFX86782.1 - 0.036 14.0 0.1 0.096 12.6 0.1 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF807 PF05660.11 KFX86782.1 - 0.11 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) zf-FCS PF06467.14 KFX86784.1 - 0.12 12.3 2.0 0.31 11.0 2.0 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AMP-binding PF00501.28 KFX86785.1 - 7.5e-64 215.9 0.4 6.3e-37 127.2 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme DUF2183 PF09949.9 KFX86785.1 - 1.3e-30 105.6 0.0 3.5e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DMAP_binding PF06464.11 KFX86785.1 - 3.7e-12 47.0 2.0 6.6e-12 46.2 0.1 2.4 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.12 KFX86785.1 - 0.0027 17.7 0.3 0.0072 16.3 0.3 1.7 1 0 0 1 1 1 1 Gas vesicle protein G CarboxypepD_reg PF13620.6 KFX86785.1 - 0.052 13.8 1.4 1.1 9.6 0.1 3.2 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain DEAD PF00270.29 KFX86786.1 - 8.6e-47 159.2 0.0 1.9e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX86786.1 - 4.5e-30 104.3 0.1 9.3e-29 100.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KFX86786.1 - 0.021 13.6 0.8 0.19 10.4 0.1 2.7 1 1 2 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Acetyltransf_1 PF00583.25 KFX86787.1 - 0.0016 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX86787.1 - 0.017 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX86787.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-ribbon_3 PF13248.6 KFX86787.1 - 0.75 9.3 2.6 1.2 8.6 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Arf PF00025.21 KFX86788.1 - 3.2e-68 228.6 0.4 3.5e-68 228.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFX86788.1 - 9e-14 51.4 0.0 1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX86788.1 - 2.5e-12 47.1 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFX86788.1 - 3.3e-12 46.3 0.8 8.6e-07 28.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFX86788.1 - 7.1e-10 38.6 0.0 8.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX86788.1 - 1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFX86788.1 - 3.8e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFX86788.1 - 0.00041 20.0 0.0 0.0081 15.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFX86788.1 - 0.029 13.9 0.2 0.084 12.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 KFX86788.1 - 0.045 13.7 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KFX86788.1 - 0.13 12.3 0.0 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KFX86788.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 KFX86788.1 - 0.17 11.2 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 KFX86789.1 - 2.4e-99 333.9 48.8 6.1e-64 217.2 31.4 5.2 3 2 3 6 6 6 2 Domain of unknown function (DUF4045) PDEase_II PF02112.15 KFX86790.1 - 3.6e-53 180.9 0.0 1.1e-44 152.9 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KFX86790.1 - 0.014 15.4 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SF1-HH PF16275.5 KFX86791.1 - 1.2e-43 148.0 0.7 3.4e-43 146.5 0.7 1.8 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KFX86791.1 - 6.7e-12 44.9 11.1 1.4e-05 24.9 0.8 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KFX86791.1 - 1.9e-07 30.8 0.1 3.4e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KFX86791.1 - 1.5e-06 28.1 5.7 0.0016 18.3 3.0 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KFX86791.1 - 0.0014 18.4 7.7 0.37 10.7 1.1 3.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KFX86791.1 - 0.0017 18.1 5.0 0.46 10.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KFX86791.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.6 2 0 0 2 2 2 0 Zinc knuckle GST_N PF02798.20 KFX86792.1 - 1.4e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX86792.1 - 3e-13 49.8 0.0 6.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX86792.1 - 6.3e-13 48.9 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX86792.1 - 7.6e-12 45.3 0.0 1.9e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX86792.1 - 1.8e-10 41.0 0.0 3.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX86792.1 - 1.1e-06 28.5 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ndufs5 PF10200.9 KFX86794.1 - 8.7e-05 22.7 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KFX86794.1 - 0.0011 19.2 0.6 0.0024 18.2 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX17 PF05051.13 KFX86794.1 - 0.045 14.1 0.3 0.073 13.4 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KFX86794.1 - 0.24 11.7 2.1 0.4 11.0 2.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) BTB PF00651.31 KFX86795.1 - 3.3e-13 49.8 0.1 9.4e-13 48.4 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KFX86796.1 - 4e-08 33.5 0.0 7.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S16 PF00886.19 KFX86797.1 - 0.00087 19.3 2.9 2.2 8.4 0.0 5.4 6 0 0 6 6 6 1 Ribosomal protein S16 Piwi PF02171.17 KFX86798.1 - 5.6e-72 242.5 0.0 1e-71 241.7 0.0 1.4 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFX86798.1 - 4.7e-20 72.6 0.0 1e-19 71.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFX86798.1 - 1.5e-13 50.2 0.4 3.8e-13 48.9 0.4 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFX86798.1 - 3.3e-12 46.5 0.0 9e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KFX86798.1 - 2.4e-07 30.6 0.0 5.2e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KFX86798.1 - 0.00099 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ADH_zinc_N PF00107.26 KFX86801.1 - 4.1e-09 36.5 0.1 8.9e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX86801.1 - 5.7e-08 32.6 0.9 1.1e-06 28.4 0.1 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_Gly3P_dh_C PF07479.14 KFX86802.1 - 4.5e-44 150.2 0.0 6.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFX86802.1 - 2.4e-43 147.8 0.1 7e-43 146.3 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_23 PF13489.6 KFX86803.1 - 7.3e-12 45.4 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86803.1 - 7e-08 32.4 0.0 7.7e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86803.1 - 1.1e-06 29.2 0.0 3.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86803.1 - 1.1e-06 29.2 0.0 4.7e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86803.1 - 6.6e-05 23.6 0.0 0.00016 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KFX86803.1 - 0.0086 15.6 0.0 0.045 13.2 0.0 2.0 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KFX86803.1 - 0.06 13.5 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KFX86803.1 - 0.19 11.0 0.0 0.41 10.0 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF832 PF05734.11 KFX86804.1 - 0.15 11.5 0.2 0.29 10.6 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) DAHP_synth_2 PF01474.16 KFX86805.1 - 2.2e-123 412.0 0.0 1.1e-70 238.4 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family AMP-binding PF00501.28 KFX86806.1 - 1.4e-63 215.0 0.0 1.7e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX86806.1 - 2e-08 35.1 0.0 5.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cas_VVA1548 PF09652.10 KFX86806.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) SIS_2 PF13580.6 KFX86806.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 SIS domain DIOX_N PF14226.6 KFX86807.1 - 5.5e-23 82.0 0.1 9.4e-23 81.2 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX86807.1 - 7e-17 61.8 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PORR PF11955.8 KFX86807.1 - 0.042 12.8 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain ABC2_membrane PF01061.24 KFX86808.1 - 1.2e-70 237.2 52.6 2e-40 138.5 15.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFX86808.1 - 7.5e-29 101.0 0.0 1.7e-13 51.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFX86808.1 - 1.4e-17 63.3 1.0 3e-16 59.1 0.0 3.2 2 0 0 2 2 2 1 CDR ABC transporter AAA_29 PF13555.6 KFX86808.1 - 1.5e-05 24.6 1.5 0.06 13.1 0.1 4.1 3 1 1 4 4 4 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFX86808.1 - 1.6e-05 24.9 0.1 0.032 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX86808.1 - 0.00037 20.0 0.1 0.13 11.7 0.0 3.5 4 1 1 5 5 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX86808.1 - 0.00068 19.9 0.2 0.058 13.7 0.0 3.3 3 1 1 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 KFX86808.1 - 0.0024 17.8 0.5 0.007 16.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFX86808.1 - 0.0035 16.9 0.4 0.043 13.4 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFX86808.1 - 0.0036 17.5 1.1 0.019 15.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFX86808.1 - 0.0038 17.5 1.0 0.018 15.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX86808.1 - 0.0065 17.0 0.0 0.054 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX86808.1 - 0.018 15.1 0.1 0.55 10.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX86808.1 - 0.019 15.3 1.0 0.84 10.0 0.3 2.8 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KFX86808.1 - 0.035 14.3 0.6 10 6.3 0.2 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFX86808.1 - 0.041 13.8 0.1 0.47 10.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 KFX86808.1 - 0.12 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 KFX86808.1 - 0.12 12.1 0.3 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFX86808.1 - 0.12 12.9 0.2 0.32 11.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX86808.1 - 0.12 12.1 0.9 0.64 9.7 0.1 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KFX86808.1 - 0.21 11.5 0.2 30 4.5 0.1 3.1 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 KFX86808.1 - 0.25 10.5 0.4 3.4 6.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Zn_clus PF00172.18 KFX86809.1 - 0.00098 19.2 10.4 0.00098 19.2 10.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFX86809.1 - 0.0022 18.3 1.2 0.0086 16.5 1.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type EcKinase PF02958.20 KFX86810.1 - 5e-05 22.7 0.1 7.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFX86810.1 - 0.00056 19.6 0.1 0.00079 19.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFX86810.1 - 0.00069 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.18 KFX86811.1 - 2e-28 99.6 11.3 8e-23 81.2 7.8 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF503 PF04456.12 KFX86811.1 - 0.038 13.8 0.1 0.094 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF503) SQS_PSY PF00494.19 KFX86812.1 - 1.1e-53 182.4 0.0 1.6e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KFX86813.1 - 1.3e-72 244.4 0.0 1.8e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFX86813.1 - 1.9e-25 88.6 0.0 3.9e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFX86813.1 - 1.3e-14 54.4 0.0 2.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX86813.1 - 1.8e-06 28.1 0.0 4.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KFX86813.1 - 6.8e-05 22.6 8.0 0.00013 21.8 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX86813.1 - 0.00033 20.4 4.7 0.00066 19.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX86813.1 - 0.0011 18.8 5.7 0.002 18.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX86813.1 - 0.004 17.4 8.3 0.0096 16.2 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX86813.1 - 0.042 13.9 7.7 0.087 12.9 7.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger UBA_4 PF14555.6 KFX86813.1 - 0.07 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain zf-RING_5 PF14634.6 KFX86813.1 - 0.11 12.5 7.3 0.47 10.4 7.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Carb_anhydrase PF00194.21 KFX86814.1 - 9.2e-30 104.0 0.0 5e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Sugar_tr PF00083.24 KFX86816.1 - 6.9e-68 229.5 28.3 8.4e-68 229.3 28.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX86816.1 - 3.7e-12 45.8 27.2 3.7e-12 45.8 27.2 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily AEP1 PF17049.5 KFX86816.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 S10_plectin PF03501.15 KFX86818.1 - 2.3e-26 91.7 0.2 3.2e-26 91.2 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 KFX86819.1 - 3.9e-69 231.7 0.6 7.3e-69 230.8 0.6 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain PEHE PF15275.6 KFX86819.1 - 0.086 13.5 3.0 0.25 12.0 3.0 1.9 1 0 0 1 1 1 0 PEHE domain COX6B PF02297.17 KFX86820.1 - 1.2e-19 70.3 5.3 1.5e-19 70.0 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KFX86820.1 - 0.024 14.7 1.8 0.035 14.1 1.2 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KFX86820.1 - 0.072 13.0 1.9 0.13 12.2 1.9 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KFX86820.1 - 0.074 12.6 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain B12D PF06522.11 KFX86821.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KFX86822.1 - 4.7e-16 58.4 0.0 7.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX86822.1 - 0.0036 17.4 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFX86822.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HECT PF00632.25 KFX86823.1 - 9.9e-69 232.2 0.0 1.4e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SRA1 PF07304.11 KFX86823.1 - 3.5e-07 30.1 0.0 3.5e-07 30.1 0.0 3.8 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KFX86823.1 - 1.2e-06 28.5 0.1 1.4e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KFX86823.1 - 1.8e-05 25.4 0.3 0.049 14.5 0.0 5.3 4 0 0 4 4 4 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 KFX86823.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain C1_1 PF00130.22 KFX86823.1 - 0.1 12.5 0.4 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) L51_S25_CI-B8 PF05047.16 KFX86824.1 - 3.5e-19 68.5 0.2 5.9e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 KFX86825.1 - 0.00014 21.9 0.1 0.012 15.7 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase UCH_1 PF13423.6 KFX86825.1 - 0.16 11.5 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L16 PF00252.18 KFX86826.1 - 5.6e-30 104.0 0.1 7.1e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KFX86827.1 - 9.8e-61 204.5 0.4 3.3e-59 199.6 0.0 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFX86827.1 - 8.5e-15 54.9 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFX86827.1 - 3.9e-08 33.8 0.1 2.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFX86827.1 - 2.8e-07 30.6 0.0 6.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFX86827.1 - 4.7e-05 23.7 0.0 0.00015 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX86827.1 - 0.00019 22.0 0.7 0.016 15.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX86827.1 - 0.0034 17.2 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX86827.1 - 0.015 15.7 1.3 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KFX86827.1 - 0.018 15.3 0.5 0.11 12.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain DNA_pol3_delta PF06144.13 KFX86827.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFX86827.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX86827.1 - 0.083 13.0 1.9 0.19 11.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KFX86827.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 KFX86827.1 - 0.098 13.0 3.0 0.25 11.7 0.0 3.0 3 0 0 3 3 2 0 AAA C-terminal domain RNA_helicase PF00910.22 KFX86827.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF1682 PF07946.14 KFX86827.1 - 0.58 9.3 7.3 2 7.5 7.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAA_17 PF13207.6 KFX86827.1 - 0.88 10.0 9.0 1.2 9.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 KFX86827.1 - 3.5 7.5 8.6 10 5.9 2.5 3.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ECH_1 PF00378.20 KFX86828.1 - 1.7e-25 89.8 0.0 2.7e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX86828.1 - 2.7e-11 43.6 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 KFX86828.1 - 6.8e-07 28.6 0.0 1.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ACOX PF01756.19 KFX86829.1 - 1.5e-43 148.4 0.0 7.6e-43 146.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 KFX86829.1 - 0.032 14.4 0.2 0.5 10.6 0.2 2.2 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2019 PF09450.10 KFX86829.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) MFS_1 PF07690.16 KFX86830.1 - 1.3e-28 99.9 37.8 1.3e-28 99.9 37.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFX86830.1 - 0.066 11.5 11.4 0.012 13.9 6.3 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 KFX86831.1 - 3.4e-55 187.4 0.0 4.2e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX86831.1 - 1e-10 42.4 0.0 3.3e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SOG2 PF10428.9 KFX86832.1 - 5.6e-69 233.7 4.9 1.8e-50 172.6 0.2 3.7 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 KFX86832.1 - 5.4e-17 61.3 2.6 1.5e-08 34.3 0.6 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFX86832.1 - 2.4e-15 56.4 2.9 2e-05 24.8 0.0 3.8 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFX86832.1 - 0.00044 20.1 4.5 5.5 7.3 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 KFX86832.1 - 0.003 17.9 6.4 3.5 8.5 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat HemN_C PF06969.16 KFX86832.1 - 0.018 15.1 0.1 0.38 10.9 0.0 2.9 3 1 1 4 4 4 0 HemN C-terminal domain MRP-S25 PF13741.6 KFX86833.1 - 2.2e-73 246.6 7.6 5.4e-71 238.8 7.6 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KFX86833.1 - 0.033 14.5 1.6 0.092 13.0 1.0 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 KFX86834.1 - 4.7e-16 58.7 4.2 0.00049 20.2 0.0 5.2 3 2 2 5 5 5 4 PPR repeat family PPR PF01535.20 KFX86834.1 - 1.1e-10 41.0 5.6 7.8e-05 22.7 0.1 5.3 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 KFX86834.1 - 5.9e-05 23.1 1.0 0.032 14.3 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFX86834.1 - 0.00058 19.5 2.8 0.023 14.4 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 KFX86834.1 - 0.0016 17.9 0.7 0.0048 16.3 0.3 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP WD40 PF00400.32 KFX86835.1 - 3e-23 81.7 6.5 3.9e-06 27.5 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX86835.1 - 6.6e-14 52.0 0.5 0.0025 18.1 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFX86835.1 - 2.2e-07 29.7 0.3 2e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KFX86835.1 - 6.2e-05 22.5 0.5 0.073 12.4 0.0 3.5 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KFX86835.1 - 0.00017 21.5 0.0 0.022 14.6 0.0 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFX86835.1 - 0.011 14.9 0.0 0.042 12.9 0.0 1.5 1 1 1 2 2 2 0 Coatomer WD associated region WD40_like PF17005.5 KFX86835.1 - 0.011 15.1 0.0 1.6 8.0 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KFX86835.1 - 0.031 13.2 0.1 3 6.7 0.0 3.1 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KFX86835.1 - 0.059 12.3 0.1 0.46 9.3 0.1 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 KFX86835.1 - 0.13 11.3 0.0 0.38 9.7 0.0 1.6 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Ribosomal_L32p PF01783.23 KFX86836.1 - 9.9e-14 51.3 2.1 9.9e-14 51.3 2.1 1.5 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KFX86836.1 - 0.0036 16.6 1.0 0.006 16.0 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFX86836.1 - 0.012 15.5 0.4 0.018 15.0 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbons Septin PF00735.18 KFX86837.1 - 6e-112 373.5 0.3 7.1e-112 373.3 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFX86837.1 - 7.2e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFX86837.1 - 5e-06 26.0 0.0 8.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KFX86837.1 - 3.6e-05 23.7 0.2 0.00028 20.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFX86837.1 - 0.00022 20.8 0.6 0.016 14.7 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFX86837.1 - 0.00049 20.2 0.3 1.5 8.9 0.0 2.5 1 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 KFX86837.1 - 0.0022 18.4 0.1 0.0085 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFX86837.1 - 0.0066 16.0 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KFX86837.1 - 0.0077 15.5 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KFX86837.1 - 0.0092 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFX86837.1 - 0.013 16.0 0.2 0.024 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KFX86837.1 - 0.044 14.3 0.1 0.095 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFX86837.1 - 0.046 12.9 0.5 0.14 11.3 0.5 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KFX86837.1 - 0.061 12.7 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFX86837.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 KFX86837.1 - 0.093 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 KFX86837.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFX86837.1 - 0.2 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_UL49_5 PF05702.11 KFX86838.1 - 0.047 13.8 0.2 0.093 12.8 0.2 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein AF-4 PF05110.13 KFX86838.1 - 2 6.4 13.2 2.3 6.2 13.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SEEEED PF14797.6 KFX86838.1 - 2.1 8.5 18.5 3.4 7.8 18.5 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Ydc2-catalyt PF09159.10 KFX86839.1 - 4.5e-71 239.9 0.0 5.6e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KFX86839.1 - 1.4e-06 28.5 0.6 0.015 15.4 0.0 3.3 3 1 0 3 3 3 2 Poxvirus A22 protein SAP PF02037.27 KFX86839.1 - 2.3e-05 24.0 0.1 4.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain Pyr_redox_2 PF07992.14 KFX86840.1 - 3.4e-58 197.2 3.5 3.4e-58 197.2 3.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFX86840.1 - 5.2e-34 116.8 0.1 1.5e-32 112.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFX86840.1 - 1.1e-17 64.3 1.4 1.4e-16 60.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX86840.1 - 6.1e-14 52.0 0.7 9.1e-14 51.4 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 KFX86840.1 - 3.8e-10 39.8 0.0 7.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86840.1 - 8.6e-10 39.1 0.0 3e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86840.1 - 9.2e-08 32.7 0.0 2.9e-07 31.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86840.1 - 1.7e-07 31.9 0.5 4.3e-07 30.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86840.1 - 2.5e-07 30.6 0.0 7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain K_oxygenase PF13434.6 KFX86840.1 - 0.0022 17.2 0.0 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KFX86840.1 - 0.02 14.3 0.3 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX86840.1 - 0.028 13.5 4.1 0.28 10.2 1.7 2.9 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 KFX86840.1 - 0.04 13.1 0.1 0.082 12.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 KFX86840.1 - 0.1 11.9 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFX86840.1 - 0.14 11.4 0.7 5.6 6.2 0.7 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFX86840.1 - 0.16 11.0 1.3 0.46 9.5 1.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFX86840.1 - 0.2 11.9 2.2 0.58 10.4 2.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX86840.1 - 1 8.0 7.0 3.2 6.4 0.9 3.3 3 1 1 4 4 4 0 HI0933-like protein Guanylate_kin PF00625.21 KFX86841.1 - 2.3e-46 157.7 0.8 2.3e-46 157.7 0.8 2.1 3 0 0 3 3 3 1 Guanylate kinase Helicase_C PF00271.31 KFX86841.1 - 4.3e-18 65.7 0.0 4.3e-14 52.8 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KFX86841.1 - 7.4e-17 61.7 0.0 1.5e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KFX86841.1 - 3.8e-10 40.3 3.1 2.3e-09 37.9 3.1 2.3 2 0 0 2 2 2 1 RecQ zinc-binding sCache_like PF16736.5 KFX86841.1 - 0.027 14.6 0.3 6.9 6.8 0.1 3.3 3 0 0 3 3 3 0 Single Cache-like Glyco_hydro_15 PF00723.21 KFX86842.1 - 1.2e-09 37.5 0.1 6.7e-07 28.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_72 PF03198.14 KFX86842.1 - 0.12 11.6 0.1 0.77 8.9 0.0 1.9 2 0 0 2 2 2 0 Glucanosyltransferase T5orf172 PF10544.9 KFX86843.1 - 2.9e-19 69.5 0.4 4.4e-18 65.7 0.3 2.7 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KFX86843.1 - 4.8e-11 43.2 0.5 2.9e-08 34.3 0.2 2.5 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 Mitofilin PF09731.9 KFX86843.1 - 0.37 9.6 39.5 0.53 9.1 39.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Alg14 PF08660.11 KFX86845.1 - 0.35 10.8 4.5 14 5.6 0.2 2.2 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like IF4E PF01652.18 KFX86847.1 - 7.5e-56 188.3 0.1 1e-55 187.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 KFX86848.1 - 8.5e-34 117.3 0.0 2.3e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain F-box-like PF12937.7 KFX86849.1 - 7.5e-07 28.9 3.4 7.7e-07 28.9 0.6 2.5 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KFX86849.1 - 0.0013 19.1 0.9 7.5 7.1 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) zf-CW PF07496.15 KFX86849.1 - 0.12 12.4 1.2 17 5.6 0.0 2.4 2 0 0 2 2 2 0 CW-type Zinc Finger Mannosyl_trans PF05007.13 KFX86850.1 - 3.6e-75 253.2 15.7 5.9e-75 252.5 15.7 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFX86850.1 - 2e-08 33.7 21.5 4.4e-08 32.6 21.5 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KFX86850.1 - 0.00014 21.7 18.9 0.00014 21.7 18.9 2.6 1 1 2 3 3 3 1 Glycosyltransferase family 87 HPD PF05044.12 KFX86850.1 - 0.052 13.4 0.3 0.088 12.7 0.3 1.3 1 0 0 1 1 1 0 Homeo-prospero domain Translin PF01997.16 KFX86851.1 - 6.8e-60 202.6 0.0 8.4e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Translin family BolA PF01722.18 KFX86852.1 - 2e-30 104.9 2.2 2.4e-30 104.6 2.2 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 KFX86853.1 - 6e-69 232.7 0.0 7.9e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX86853.1 - 1.3e-15 58.1 0.1 2.6e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 KFX86854.1 - 6.2e-54 182.1 0.2 7.7e-54 181.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 KFX86855.1 - 6.5e-22 77.5 2.0 1.1e-21 76.8 2.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPP1 PF10341.9 KFX86855.1 - 3e-06 27.2 0.0 6.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PIP5K PF01504.18 KFX86856.1 - 9e-34 116.9 1.6 2.3e-25 89.4 0.1 2.9 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KFX86856.1 - 8.1e-27 94.0 0.1 1.5e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFX86856.1 - 7.7e-12 45.2 9.8 7.7e-12 45.2 9.8 1.7 2 0 0 2 2 2 1 FYVE zinc finger Metallophos PF00149.28 KFX86857.1 - 1.4e-35 123.7 0.1 2.2e-35 123.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX86857.1 - 6e-16 58.6 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SET PF00856.28 KFX86858.1 - 4.6e-14 53.2 0.1 4.6e-14 53.2 0.1 2.5 2 2 0 2 2 2 1 SET domain Ezh2_MCSS PF18600.1 KFX86858.1 - 0.00066 19.2 0.4 0.0015 18.1 0.4 1.6 1 0 0 1 1 1 1 MCSS domain RPEL PF02755.15 KFX86859.1 - 1e-25 88.6 18.8 1e-09 37.7 3.6 4.0 4 0 0 4 4 4 3 RPEL repeat IMS PF00817.20 KFX86860.1 - 5.2e-41 140.1 0.1 1.3e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFX86860.1 - 9e-10 39.3 0.0 2.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFX86860.1 - 0.0021 18.3 0.0 0.0059 16.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PHD20L1_u1 PF16660.5 KFX86860.1 - 0.093 13.5 9.7 0.57 11.0 4.2 2.5 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 FKBP_C PF00254.28 KFX86861.1 - 3.1e-33 114.0 0.0 4.9e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I53 PF11714.8 KFX86861.1 - 0.1 12.8 0.6 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Pkinase PF00069.25 KFX86864.1 - 4.8e-50 170.4 0.0 8.3e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86864.1 - 9.2e-28 97.2 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX86864.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX86864.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFX86864.1 - 0.15 12.0 0.4 1.6 8.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX86864.1 - 0.19 11.3 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NTP_transferase PF00483.23 KFX86865.1 - 5.6e-52 176.8 0.0 9.3e-52 176.1 0.0 1.3 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KFX86865.1 - 6.4e-16 57.4 11.2 2.8e-10 39.5 2.0 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFX86865.1 - 1.2e-10 41.9 0.0 1.7e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFX86865.1 - 8.4e-06 25.4 1.7 8.4e-06 25.4 1.7 3.0 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFX86865.1 - 2.6e-05 22.6 0.1 5.7e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Transket_pyr PF02779.24 KFX86866.1 - 1.9e-63 213.3 0.0 3.3e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFX86866.1 - 4.6e-57 193.2 0.0 6.8e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFX86866.1 - 8e-56 188.0 0.0 1.3e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFX86866.1 - 2.8e-19 68.4 1.8 6.6e-19 67.2 1.8 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus BSD PF03909.17 KFX86867.1 - 1.4e-27 95.4 5.7 2e-13 50.1 0.4 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KFX86867.1 - 7.2e-25 87.1 0.0 1.8e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Rx_N PF18052.1 KFX86867.1 - 0.039 14.2 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 Rx N-terminal domain DUF4363 PF14276.6 KFX86867.1 - 0.15 12.2 0.6 0.47 10.6 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) MCU PF04678.13 KFX86869.1 - 1.5e-25 90.3 0.7 1.5e-25 90.3 0.7 1.9 1 1 1 2 2 2 1 Mitochondrial calcium uniporter RNase_J_C PF17770.1 KFX86869.1 - 0.12 13.5 0.3 0.22 12.6 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain ATP-synt_B PF00430.18 KFX86869.1 - 0.25 11.5 3.5 0.45 10.6 3.5 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Vfa1 PF08432.10 KFX86869.1 - 0.54 10.6 7.2 0.69 10.2 7.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Apolipoprotein PF01442.18 KFX86871.1 - 0.00023 21.1 10.1 0.00033 20.6 4.0 2.3 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Gp58 PF07902.11 KFX86871.1 - 0.0012 17.3 4.9 0.0024 16.3 4.9 1.5 1 1 0 1 1 1 1 gp58-like protein FAM184 PF15665.5 KFX86871.1 - 0.028 14.2 0.8 0.028 14.2 0.8 2.6 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B Prominin PF05478.11 KFX86871.1 - 0.16 9.9 0.8 0.27 9.1 0.8 1.4 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 KFX86871.1 - 0.22 11.9 12.0 2.5 8.4 12.0 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) VPS38 PF17649.1 KFX86871.1 - 0.23 10.3 1.7 0.42 9.4 1.7 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 RNase_J_C PF17770.1 KFX86871.1 - 0.28 12.3 2.4 8.5 7.5 0.2 3.3 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain DUF4404 PF14357.6 KFX86871.1 - 0.53 10.9 8.9 0.32 11.7 2.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 KFX86871.1 - 0.84 9.7 4.2 0.63 10.1 0.8 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Chalcone_2 PF16035.5 KFX86871.1 - 0.86 9.3 5.9 0.33 10.7 1.1 2.4 1 1 1 2 2 2 0 Chalcone isomerase like DUF1515 PF07439.11 KFX86871.1 - 1.1 9.3 4.3 1.4 9.0 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) AAA_13 PF13166.6 KFX86871.1 - 4.2 5.9 11.3 0.31 9.6 3.7 1.8 1 1 1 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 KFX86871.1 - 5.9 7.6 14.2 0.8 10.3 6.7 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Muted PF14942.6 KFX86871.1 - 7.3 6.9 12.1 1.2 9.5 5.4 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Rho_Binding PF08912.11 KFX86871.1 - 7.3 7.5 9.7 8.2 7.3 1.2 3.6 2 1 1 3 3 3 0 Rho Binding DEAD PF00270.29 KFX86872.1 - 3e-46 157.4 1.0 4.8e-46 156.7 1.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX86872.1 - 2e-31 108.6 0.2 1.7e-30 105.6 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX86872.1 - 1.7e-06 28.2 0.0 2.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFX86872.1 - 0.00047 19.9 0.1 0.00096 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX86872.1 - 0.0015 18.9 0.6 0.011 16.1 0.3 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KFX86872.1 - 0.0092 16.0 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 KFX86872.1 - 0.017 15.4 0.4 0.083 13.2 0.4 2.1 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KFX86872.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KFX86872.1 - 0.11 12.4 0.1 0.57 10.1 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain fragilysinNterm PF16376.5 KFX86872.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of fragilysin UvrD-helicase PF00580.21 KFX86872.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NuA4 PF09340.10 KFX86873.1 - 8.6e-25 86.4 0.1 1.7e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 SIMPL PF04402.14 KFX86877.1 - 1.6e-26 94.0 3.3 1.9e-26 93.8 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Fungal_trans_2 PF11951.8 KFX86878.1 - 7.4e-20 71.1 0.0 1.3e-19 70.3 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX86878.1 - 4.5e-05 23.5 10.7 7.7e-05 22.7 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 KFX86879.1 - 4.4e-15 55.1 0.0 5.7e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFX86879.1 - 3.2e-07 29.5 0.0 8.5e-07 28.1 0.0 1.7 2 1 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KFX86879.1 - 0.0016 18.2 0.3 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX86879.1 - 0.0035 16.6 0.1 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFX86879.1 - 0.0098 14.9 0.5 0.14 11.1 0.5 2.1 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 KFX86879.1 - 0.013 16.2 0.1 0.023 15.3 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX86879.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Beta-lactamase PF00144.24 KFX86880.1 - 8.3e-45 153.4 0.0 1.2e-44 153.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KFX86880.1 - 3e-11 43.7 0.0 4.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ribonucleas_3_3 PF14622.6 KFX86881.1 - 9e-09 35.6 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFX86881.1 - 1.1e-07 32.4 0.0 3.2e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain RabGAP-TBC PF00566.18 KFX86882.1 - 2.5e-35 122.1 0.0 3.2e-32 111.9 0.0 2.6 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Sod_Fe_C PF02777.18 KFX86883.1 - 2.4e-35 120.8 2.2 2.6e-35 120.7 0.5 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFX86883.1 - 5.5e-29 100.5 2.3 9e-29 99.8 2.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ChaB PF06150.12 KFX86883.1 - 0.02 15.5 0.7 0.06 13.9 0.7 1.8 1 0 0 1 1 1 0 ChaB DUF4211 PF13926.6 KFX86885.1 - 3e-15 56.5 0.1 2.1e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CENP-B_dimeris PF09026.10 KFX86885.1 - 0.00063 20.1 1.2 0.00097 19.5 1.2 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF2201_N PF13203.6 KFX86885.1 - 0.0037 16.9 0.0 0.0066 16.1 0.0 1.3 1 1 0 1 1 1 1 Putative metallopeptidase domain PBP1_TM PF14812.6 KFX86885.1 - 0.043 14.2 1.4 0.096 13.1 1.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.21 KFX86886.1 - 3.4e-62 210.4 0.9 1.3e-50 172.5 0.4 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C Snf7 PF03357.21 KFX86887.1 - 2.5e-35 121.6 19.7 2.5e-35 121.6 19.7 1.3 2 0 0 2 2 2 1 Snf7 DUF592 PF04574.13 KFX86887.1 - 0.81 9.4 3.9 8.5 6.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF592) Hpt PF01627.23 KFX86887.1 - 1.5 9.1 5.4 0.42 10.9 1.3 2.2 2 1 0 2 2 2 0 Hpt domain Aminotran_3 PF00202.21 KFX86888.1 - 6.5e-48 163.4 0.1 1.4e-47 162.3 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-III NifW PF03206.14 KFX86888.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW RITA PF17066.5 KFX86891.1 - 0.063 12.9 0.1 0.11 12.0 0.0 1.4 2 0 0 2 2 2 0 RBPJ-interacting and tubulin associated protein Pkinase PF00069.25 KFX86893.1 - 9.4e-71 238.3 0.0 1.4e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86893.1 - 6.8e-35 120.6 0.0 1.3e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX86893.1 - 0.00036 20.0 0.1 0.00072 19.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX86893.1 - 0.0073 15.7 0.1 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX86893.1 - 0.0074 15.3 0.4 0.096 11.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFX86893.1 - 0.051 12.4 0.0 0.051 12.4 0.0 3.8 4 1 0 4 4 4 0 Fungal protein kinase Ribosomal_L19 PF01245.20 KFX86895.1 - 4.6e-14 52.3 0.2 7.3e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 RRP36 PF06102.12 KFX86896.1 - 0.056 13.4 0.6 0.81 9.6 0.1 2.3 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 PALP PF00291.25 KFX86897.1 - 3.9e-67 226.7 0.3 4.5e-67 226.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 KFX86898.1 - 2e-95 319.4 3.7 2.8e-95 318.9 0.5 2.7 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KFX86898.1 - 1.1e-08 34.6 9.3 0.038 14.3 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KFX86898.1 - 6.8e-08 32.8 9.3 6.3e-05 23.3 1.9 4.4 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 KFX86898.1 - 6.5e-05 23.0 2.3 1.2 9.2 0.1 4.7 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 FANCI_HD1 PF14679.6 KFX86898.1 - 0.0082 16.1 0.1 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 FANCI helical domain 1 RTP1_C1 PF10363.9 KFX86898.1 - 0.034 14.3 3.6 14 5.9 0.1 4.4 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KFX86898.1 - 0.039 13.2 2.6 2.4 7.3 0.2 3.2 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 KFX86898.1 - 1.5 9.4 10.1 0.54 10.8 0.3 5.1 5 2 1 6 6 6 0 HEAT-like repeat PARG_cat PF05028.14 KFX86899.1 - 4.7e-55 187.2 0.0 6.3e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) NAP PF00956.18 KFX86900.1 - 9.2e-30 103.7 1.3 4.2e-28 98.3 0.4 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Tau95 PF09734.9 KFX86901.1 - 1.4e-38 132.9 0.2 3.4e-38 131.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFX86901.1 - 7.3e-37 126.4 0.0 1.7e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain NOA36 PF06524.12 KFX86901.1 - 1.2 8.4 14.5 2.7 7.2 14.5 1.5 1 1 0 1 1 1 0 NOA36 protein B56 PF01603.20 KFX86902.1 - 1.7e-190 633.4 5.1 2e-190 633.1 5.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFX86902.1 - 0.0008 19.3 2.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 KFX86902.1 - 0.15 11.6 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Myotubularin protein Syntaxin-6_N PF09177.11 KFX86903.1 - 8.8e-26 90.4 0.9 1.1e-24 86.9 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.9 KFX86903.1 - 0.00041 20.2 0.4 0.00052 19.8 0.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KFX86903.1 - 0.0035 17.3 3.8 0.0053 16.7 0.5 2.3 2 0 0 2 2 2 1 SNARE domain CdvA PF18822.1 KFX86903.1 - 0.021 14.6 1.2 0.26 11.1 0.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Tropomyosin_1 PF12718.7 KFX86903.1 - 0.06 13.5 10.5 0.065 13.4 8.6 1.8 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.12 KFX86903.1 - 0.064 13.3 4.7 0.7 9.9 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Ada3 PF10198.9 KFX86903.1 - 0.15 12.2 5.0 1.1 9.4 5.0 2.2 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 UPF0242 PF06785.11 KFX86903.1 - 0.17 12.0 5.7 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lipoprotein_20 PF13942.6 KFX86903.1 - 0.25 11.2 3.2 0.57 10.1 3.2 1.6 1 1 0 1 1 1 0 YfhG lipoprotein OmpH PF03938.14 KFX86903.1 - 0.26 11.6 11.6 4.9 7.5 11.6 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Adaptin_binding PF10199.9 KFX86903.1 - 0.35 11.5 7.4 3.7 8.2 7.4 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2205 PF10224.9 KFX86903.1 - 3.2 7.8 7.7 4.1 7.5 0.0 3.4 3 1 0 3 3 3 0 Short coiled-coil protein Golgin_A5 PF09787.9 KFX86903.1 - 5.4 6.4 11.2 11 5.4 10.4 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 Methyltransf_32 PF13679.6 KFX86904.1 - 8.9e-21 74.5 3.4 4.2e-20 72.3 3.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF669 PF05037.13 KFX86904.1 - 0.095 12.8 0.0 17 5.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF669) Sdh_cyt PF01127.22 KFX86905.1 - 4e-25 88.2 4.0 5.1e-25 87.9 4.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 KFX86906.1 - 1.5e-30 105.3 0.0 2.1e-29 101.7 0.0 2.5 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KFX86906.1 - 4.1e-21 74.9 0.1 8.9e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Adaptin_N PF01602.20 KFX86906.1 - 0.054 12.1 1.9 0.04 12.5 0.6 1.4 2 0 0 2 2 2 0 Adaptin N terminal region Thymidylate_kin PF02223.17 KFX86907.1 - 2.9e-49 167.3 0.0 3.4e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KFX86907.1 - 1.9e-07 31.5 0.0 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KFX86907.1 - 0.0019 18.0 0.0 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 KFX86907.1 - 0.0068 15.9 0.9 0.015 14.7 0.1 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 dNK PF01712.19 KFX86907.1 - 0.0082 16.0 0.1 0.066 13.0 0.1 2.0 1 1 0 1 1 1 1 Deoxynucleoside kinase DUF2235 PF09994.9 KFX86907.1 - 0.014 14.8 0.1 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SKI PF01202.22 KFX86907.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.6 KFX86907.1 - 0.1 13.1 0.1 0.94 10.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain GTP_cyclohydroI PF01227.22 KFX86908.1 - 3.8e-73 244.7 0.1 4.9e-73 244.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFX86908.1 - 0.018 15.2 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein DUF4710 PF15828.5 KFX86908.1 - 0.17 12.1 1.5 0.83 9.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) HATPase_c PF02518.26 KFX86909.1 - 2.9e-18 66.4 0.2 2.5e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX86909.1 - 1.7e-05 24.7 0.0 6.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KFX86909.1 - 0.00019 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KFX86909.1 - 0.036 14.4 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 GAF domain iPGM_N PF06415.13 KFX86910.1 - 8.6e-79 264.0 0.0 1.4e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KFX86910.1 - 2.5e-68 230.1 0.1 2.9e-68 229.9 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFX86910.1 - 3.3e-08 33.3 0.0 1.2e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFX86910.1 - 8.7e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KFX86910.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Med9 PF07544.13 KFX86911.1 - 8.1e-16 57.9 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HHH_8 PF14716.6 KFX86911.1 - 0.0032 17.8 1.1 0.96 9.9 0.1 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain Med21 PF11221.8 KFX86911.1 - 0.014 15.7 8.5 0.024 14.9 8.5 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TBCC PF07986.12 KFX86912.1 - 1.3e-30 105.6 0.4 2.3e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFX86912.1 - 1e-10 42.0 0.2 2.4e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain PHM7_cyt PF14703.6 KFX86912.1 - 0.04 14.1 0.7 2.7 8.2 0.0 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Tim17 PF02466.19 KFX86913.1 - 8e-09 35.9 7.3 1.4e-08 35.1 7.3 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 KFX86914.1 - 1e-37 127.8 1.0 2.8e-13 49.6 0.2 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KFX86914.1 - 1.9e-34 119.3 2.8 1.3e-33 116.6 2.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX86914.1 - 3.9e-06 26.7 0.1 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase VTC PF09359.10 KFX86914.1 - 0.037 13.4 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 VTC domain Mito_carr PF00153.27 KFX86916.1 - 9.6e-55 182.5 3.8 1.7e-19 69.5 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 KFX86916.1 - 1.5e-49 167.7 3.3 3.3e-49 166.6 3.3 1.6 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 KFX86916.1 - 1.5 9.1 4.0 2 8.7 0.5 2.8 3 0 0 3 3 3 0 Phasin protein RCC1 PF00415.18 KFX86917.1 - 2.4e-25 88.9 9.6 8.2e-06 26.4 0.0 8.0 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFX86917.1 - 5.5e-12 45.2 16.0 1.5e-07 31.0 0.4 6.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DDHD PF02862.17 KFX86918.1 - 0.027 14.7 7.9 0.037 14.2 7.9 1.3 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 KFX86918.1 - 0.22 10.0 22.5 0.27 9.7 22.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 KFX86918.1 - 0.23 9.7 24.4 0.35 9.1 24.4 1.3 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KFX86918.1 - 0.28 10.2 16.1 0.34 10.0 16.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPP4R2 PF09184.11 KFX86918.1 - 0.71 9.4 16.4 1 8.9 16.4 1.2 1 0 0 1 1 1 0 PPP4R2 CRT10 PF08728.10 KFX86918.1 - 1.1 7.3 11.9 1.3 7.1 11.9 1.0 1 0 0 1 1 1 0 CRT10 LMBR1 PF04791.16 KFX86918.1 - 2.2 7.1 12.9 2.8 6.7 12.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMEM174 PF15029.6 KFX86918.1 - 2.4 7.8 4.1 3.8 7.2 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 Dsh_C PF12316.8 KFX86918.1 - 2.4 8.5 8.9 3.6 7.9 8.9 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SOBP PF15279.6 KFX86918.1 - 3.7 8.1 10.7 4.8 7.7 10.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 KFX86918.1 - 4.2 7.1 24.2 6.6 6.5 24.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KFX86918.1 - 4.3 6.2 8.8 7.1 5.5 8.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 KFX86918.1 - 8.1 5.7 17.9 15 4.9 17.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 KFX86918.1 - 8.5 5.0 12.0 11 4.7 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 KFX86918.1 - 8.5 6.1 17.1 13 5.4 17.1 1.3 1 0 0 1 1 1 0 AAA domain DUF5427 PF10310.9 KFX86918.1 - 8.9 5.1 26.4 12 4.7 26.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hid1 PF12722.7 KFX86918.1 - 9.8 4.2 21.6 13 3.7 21.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DEAD PF00270.29 KFX86920.1 - 1.6e-43 148.5 0.0 2.4e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX86920.1 - 9.7e-28 96.7 1.0 6.4e-27 94.1 0.4 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX86920.1 - 5.4e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFX86920.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TFIIA PF03153.13 KFX86920.1 - 7.3 6.5 20.8 11 5.9 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CoA_trans PF01144.23 KFX86921.1 - 5.3e-99 330.0 2.2 1.9e-62 210.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D5 PF17406.2 KFX86922.1 - 7.2e-61 204.7 0.1 1.2e-60 203.9 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KFX86922.1 - 1.1e-59 201.3 0.1 2.1e-59 200.4 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KFX86922.1 - 4e-51 172.8 0.0 2e-47 160.8 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KFX86922.1 - 9.3e-49 165.4 0.0 1.8e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KFX86922.1 - 8.9e-48 162.4 0.0 1.8e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KFX86922.1 - 6.1e-34 117.1 0.0 1.6e-33 115.8 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 KFX86923.1 - 6.3e-27 94.1 0.0 1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SMC_N PF02463.19 KFX86923.1 - 1.2e-23 83.7 0.9 2.1e-23 82.9 0.9 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX86923.1 - 8e-15 55.9 24.6 8e-15 55.9 24.6 5.2 2 2 2 4 4 4 2 AAA domain AAA_15 PF13175.6 KFX86923.1 - 7.1e-12 45.7 12.9 7.1e-12 45.7 12.9 3.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 KFX86923.1 - 9e-07 29.0 1.2 6.9e-05 22.8 0.6 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX86923.1 - 0.0002 21.0 0.3 0.00069 19.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 KFX86923.1 - 0.00039 20.7 0.0 0.0017 18.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Pkinase PF00069.25 KFX86924.1 - 4e-26 91.9 0.0 1.7e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86924.1 - 5.9e-06 25.8 0.3 0.00015 21.1 0.3 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX86924.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Rad17 PF03215.15 KFX86925.1 - 6.4e-26 91.4 0.0 1.7e-25 90.0 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KFX86925.1 - 0.00065 20.1 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX86925.1 - 0.0033 17.8 0.1 0.01 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFX86925.1 - 0.0039 17.2 0.1 0.0095 15.9 0.1 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KFX86925.1 - 0.0058 16.9 0.0 0.041 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX86925.1 - 0.0059 16.4 0.2 0.015 15.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFX86925.1 - 0.014 15.4 0.2 0.049 13.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KFX86925.1 - 0.031 14.6 0.1 0.078 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFX86925.1 - 0.038 14.5 0.0 0.082 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KFX86925.1 - 0.045 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 KFX86925.1 - 0.069 13.3 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFX86925.1 - 0.084 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFX86925.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KFX86925.1 - 0.17 11.8 0.4 0.36 10.7 0.4 1.5 1 0 0 1 1 1 0 NACHT domain Pneumo_att_G PF05539.11 KFX86925.1 - 4.4 6.8 13.7 7.9 6.0 13.7 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF853 PF05872.12 KFX86925.1 - 4.5 5.8 7.0 0.21 10.2 0.4 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DLIC PF05783.11 KFX86925.1 - 6.8 5.4 8.5 13 4.5 8.5 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) GFO_IDH_MocA PF01408.22 KFX86926.1 - 7.6e-23 81.6 0.0 1.4e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFX86926.1 - 0.0024 18.5 0.0 0.0038 17.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX86926.1 - 0.2 11.9 0.0 0.47 10.7 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Carn_acyltransf PF00755.20 KFX86927.1 - 3.5e-91 306.6 0.0 4.9e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KFX86927.1 - 5.3e-71 239.2 0.0 1.1e-70 238.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFX86927.1 - 2e-53 181.0 0.0 1.5e-52 178.1 0.0 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KFX86927.1 - 2.1e-53 181.9 0.3 3.3e-53 181.3 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KFX86927.1 - 1.7e-48 165.4 0.0 2.6e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFX86927.1 - 1.3e-38 131.6 0.1 3.6e-38 130.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFX86927.1 - 1.4e-17 64.2 0.0 6.3e-17 62.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KFX86927.1 - 6.2e-14 53.2 0.0 1.4e-12 48.8 0.0 3.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX86927.1 - 2.2e-13 50.3 0.1 7.6e-13 48.6 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFX86927.1 - 1.4e-12 47.4 0.0 7.7e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KFX86927.1 - 1.6e-12 47.8 0.1 4.6e-08 33.5 0.0 3.1 3 0 0 3 3 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KFX86927.1 - 3.3e-12 46.5 0.0 2.5e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86927.1 - 1.2e-11 45.2 0.0 1e-10 42.2 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86927.1 - 3.7e-11 43.5 0.0 1.8e-10 41.3 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86927.1 - 4.6e-11 42.7 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFX86927.1 - 1.7e-09 37.9 0.0 4.9e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KFX86927.1 - 6.1e-09 35.8 0.0 2.5e-08 33.8 0.0 2.0 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KFX86927.1 - 4.8e-05 22.8 0.0 9.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KFX86927.1 - 0.00017 21.0 1.4 0.00066 19.1 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KFX86927.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase 3Beta_HSD PF01073.19 KFX86927.1 - 0.00096 18.2 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.10 KFX86927.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PriX PF18689.1 KFX86927.1 - 0.14 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Primase X Polysacc_synt_2 PF02719.15 KFX86927.1 - 0.18 10.9 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.19 KFX86928.1 - 6.7e-54 183.3 0.0 8.6e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX86928.1 - 4.7e-28 98.5 0.0 1.1e-27 97.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX86928.1 - 1.2e-06 28.0 0.0 0.00024 20.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX86928.1 - 4.6e-06 26.5 2.8 0.0001 22.0 2.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX86928.1 - 6.5e-06 25.6 0.4 1.3e-05 24.6 0.2 1.5 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KFX86928.1 - 8.9e-06 25.0 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX86928.1 - 0.00015 21.1 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX86928.1 - 0.00016 21.8 0.1 0.00043 20.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX86928.1 - 0.00097 18.5 0.1 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX86928.1 - 0.0031 16.3 0.2 0.007 15.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KFX86928.1 - 0.0041 16.0 0.1 0.006 15.5 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KFX86928.1 - 0.052 13.5 0.4 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX86928.1 - 0.15 11.2 0.0 2.8 7.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KFX86928.1 - 0.25 10.6 0.9 4.1 6.6 0.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short_C2 PF13561.6 KFX86929.1 - 5.7e-13 49.0 0.0 7.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX86929.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KFX86929.1 - 0.0017 17.8 0.0 0.0052 16.3 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX86929.1 - 0.0027 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 KFX86929.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFX86929.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KFX86929.1 - 0.028 14.5 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFX86929.1 - 0.084 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BRCA-2_OB1 PF09103.10 KFX86929.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Pro-kuma_activ PF09286.11 KFX86930.1 - 1.7e-33 115.9 0.0 2.9e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KFX86930.1 - 1.7e-07 30.8 0.0 5.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Subtilase family DUF1304 PF06993.12 KFX86933.1 - 4.6e-44 148.9 4.4 5.2e-44 148.7 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Ank_2 PF12796.7 KFX86934.1 - 4.1e-18 65.8 0.0 2.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX86934.1 - 2.2e-14 52.1 0.0 0.00078 19.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFX86934.1 - 8.7e-14 51.7 0.0 3.7e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX86934.1 - 7.7e-11 41.9 0.1 0.00036 20.9 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFX86934.1 - 2.2e-08 34.2 0.0 0.0061 16.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Shigella_OspC PF06128.11 KFX86934.1 - 0.23 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein HET PF06985.11 KFX86935.1 - 1.5e-10 41.6 1.6 4.3e-07 30.4 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.11 KFX86935.1 - 0.021 14.7 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin Ivy PF08816.11 KFX86935.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) FA_desaturase PF00487.24 KFX86937.1 - 1.9e-30 106.6 22.2 2.8e-30 106.0 22.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFX86937.1 - 5.4e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.7 KFX86937.1 - 0.19 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) ASXH PF13919.6 KFX86938.1 - 4.6e-32 110.9 0.9 8e-32 110.2 0.9 1.4 1 0 0 1 1 1 1 Asx homology domain RAMA PF18755.1 KFX86938.1 - 0.015 15.7 0.0 7.2 7.1 0.0 2.8 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated Longin PF13774.6 KFX86939.1 - 1.4e-24 85.9 0.2 2.6e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFX86939.1 - 2e-15 56.3 0.0 4.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF760 PF05542.11 KFX86939.1 - 0.0087 16.4 0.2 0.096 13.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF760) Aminotran_3 PF00202.21 KFX86940.1 - 3.4e-55 187.4 0.0 3.7e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HA2 PF04408.23 KFX86941.1 - 2.4e-24 85.7 2.1 6.9e-24 84.2 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX86941.1 - 5.5e-12 46.0 0.2 1.2e-10 41.7 0.0 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX86941.1 - 1.6e-11 44.4 0.0 4.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFX86941.1 - 8.2e-07 29.0 0.0 9.2e-06 25.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX86941.1 - 0.0026 18.0 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFX86941.1 - 0.017 14.2 0.1 0.044 12.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 KFX86941.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFX86941.1 - 0.054 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 KFX86941.1 - 0.071 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC POC3_POC4 PF10448.9 KFX86942.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Transcrip_reg PF01709.20 KFX86943.1 - 2.8e-66 223.4 0.0 3.8e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator DIOX_N PF14226.6 KFX86943.1 - 3.7e-23 82.5 0.0 2.2e-22 80.0 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX86943.1 - 2.5e-20 72.9 0.0 1e-19 70.9 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily HEAT_2 PF13646.6 KFX86944.1 - 1.2e-09 38.4 2.9 0.22 11.9 0.0 7.0 6 1 2 8 8 8 4 HEAT repeats HEAT PF02985.22 KFX86944.1 - 8.9e-07 28.7 22.7 0.89 10.0 0.0 11.4 12 0 0 12 12 12 2 HEAT repeat TAF6_C PF07571.13 KFX86944.1 - 0.00033 20.9 0.6 2.9 8.3 0.0 5.7 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KFX86944.1 - 0.00044 19.9 0.3 0.74 9.3 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal Cnd3 PF12719.7 KFX86944.1 - 0.0028 16.9 3.0 2.7 7.1 0.0 5.3 4 2 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 KFX86944.1 - 0.0039 17.2 0.1 2.1 8.4 0.0 4.5 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFX86944.1 - 0.011 16.3 0.0 1.1 9.9 0.0 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFX86944.1 - 0.011 16.2 8.1 2.7 8.6 0.0 6.9 8 0 0 8 8 8 0 HEAT-like repeat NOG1_N PF17835.1 KFX86944.1 - 0.05 13.6 0.1 10 6.1 0.0 2.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain SARAF PF06682.12 KFX86945.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2207 PF09972.9 KFX86945.1 - 0.6 8.8 0.0 0.6 8.8 0.0 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Methyltransf_31 PF13847.6 KFX86946.1 - 6.9e-07 29.2 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86946.1 - 8.9e-07 29.6 0.0 1.6e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX86946.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86946.1 - 1.9e-06 28.5 0.0 1.2e-05 25.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86946.1 - 3e-05 24.6 0.1 0.00021 21.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX86946.1 - 0.0018 17.8 0.0 0.0056 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain GFA PF04828.14 KFX86947.1 - 4e-11 43.1 4.7 3.3e-05 24.1 0.3 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Desulfoferrod_N PF06397.12 KFX86947.1 - 0.15 11.7 0.4 0.15 11.7 0.4 3.5 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain ETC_C1_NDUFA4 PF04800.12 KFX86947.1 - 0.18 12.1 0.0 8.9 6.6 0.0 2.3 2 0 0 2 2 2 0 ETC complex I subunit conserved region DZR PF12773.7 KFX86947.1 - 0.2 11.7 7.5 11 6.2 0.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-CSL PF05207.13 KFX86947.1 - 0.23 11.2 14.4 0.077 12.7 1.4 3.0 4 0 0 4 4 4 0 CSL zinc finger zf-NADH-PPase PF09297.11 KFX86947.1 - 0.24 11.1 0.2 0.24 11.1 0.2 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KFX86947.1 - 1.5 8.8 14.7 2.6 8.1 0.0 4.7 6 0 0 6 6 6 0 Nudix N-terminal MFS_1 PF07690.16 KFX86948.1 - 9.9e-29 100.4 23.6 6.6e-20 71.3 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX86948.1 - 0.00021 20.3 0.5 0.00021 20.3 0.5 2.7 1 1 1 3 3 3 1 MFS_1 like family adh_short PF00106.25 KFX86949.1 - 1.8e-23 83.0 0.0 2.7e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX86949.1 - 2.2e-17 63.4 0.0 2.8e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX86949.1 - 2.1e-06 27.7 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX86949.1 - 0.00011 21.7 0.0 0.00057 19.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX86949.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX86949.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFX86949.1 - 0.17 10.9 0.0 7.9 5.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Zn_clus PF00172.18 KFX86950.1 - 1.7e-08 34.4 11.0 3.3e-08 33.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TENA_THI-4 PF03070.16 KFX86951.1 - 0.0011 18.9 0.0 0.076 12.8 0.0 2.7 2 1 1 3 3 3 2 TENA/THI-4/PQQC family MARVEL PF01284.23 KFX86952.1 - 5.4e-22 78.4 19.1 6.7e-22 78.1 19.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain Glyco_hydro_43 PF04616.14 KFX86954.1 - 7.1e-30 104.3 4.0 2.2e-18 66.6 0.7 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Methyltransf_25 PF13649.6 KFX86955.1 - 2.2e-19 70.0 0.0 3.6e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86955.1 - 1.1e-17 64.4 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86955.1 - 6.1e-13 48.8 0.0 8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX86955.1 - 4.5e-11 42.8 0.0 6.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86955.1 - 9.4e-09 35.9 0.0 1.6e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX86955.1 - 2e-06 27.3 0.0 7.7e-06 25.4 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFX86955.1 - 2.9e-05 23.5 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFX86955.1 - 7.7e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KFX86955.1 - 0.00021 21.0 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KFX86955.1 - 0.0079 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase tRNA_U5-meth_tr PF05958.11 KFX86955.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Pox_MCEL PF03291.16 KFX86955.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_18 PF12847.7 KFX86955.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFX86955.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0146 PF03686.13 KFX86955.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) ADH_N PF08240.12 KFX86956.1 - 1.4e-20 73.2 0.3 2.9e-20 72.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX86956.1 - 1.7e-09 37.7 0.0 1.5e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX86956.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFX86956.1 - 2.2e-05 23.9 0.6 3e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFX86956.1 - 0.018 15.1 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFX86956.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX86956.1 - 0.065 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFX86956.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pet100 PF09803.9 KFX86957.1 - 1e-18 67.6 1.2 2.3e-18 66.5 1.1 1.6 2 0 0 2 2 2 1 Pet100 ECH_1 PF00378.20 KFX86958.1 - 1.4e-18 67.1 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX86958.1 - 3.1e-13 49.9 0.0 3.6e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase cwf21 PF08312.12 KFX86959.1 - 5e-17 61.8 8.1 5e-17 61.8 8.1 2.1 2 0 0 2 2 2 1 cwf21 domain Cas_GSU0054 PF09609.10 KFX86959.1 - 0.031 13.0 0.1 0.04 12.6 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF1129 PF06570.11 KFX86959.1 - 0.054 13.0 0.3 0.075 12.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) D123 PF07065.14 KFX86960.1 - 1.3e-101 339.8 0.0 1.6e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3684 PF12449.8 KFX86961.1 - 0 1398.0 0.0 0 1397.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KFX86961.1 - 0.0035 17.2 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med6 PF04934.14 KFX86962.1 - 4.2e-42 143.1 0.0 6.4e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component RabGAP-TBC PF00566.18 KFX86963.1 - 1.8e-39 135.7 0.2 3.6e-39 134.6 0.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KFX86963.1 - 1.1e-05 25.0 0.0 0.00025 20.6 0.0 2.6 2 1 0 2 2 2 1 Rab-binding domain (RBD) MMtag PF10159.9 KFX86964.1 - 1.8e-31 108.2 3.2 5e-31 106.8 3.2 1.8 1 0 0 1 1 1 1 Multiple myeloma tumor-associated zf-C2H2 PF00096.26 KFX86965.1 - 0.026 15.0 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type MnmE_helical PF12631.7 KFX86968.1 - 5.9e-39 134.4 0.2 7.5e-39 134.0 0.2 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KFX86968.1 - 7.2e-34 116.6 0.0 1.4e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KFX86968.1 - 1.7e-18 66.7 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFX86968.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KFX86968.1 - 0.00032 20.3 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Glyco_hydro_3_C PF01915.22 KFX86968.1 - 0.0098 15.9 0.0 0.025 14.5 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain RsgA_GTPase PF03193.16 KFX86968.1 - 0.015 15.2 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KFX86968.1 - 0.021 14.4 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KFX86968.1 - 0.025 14.3 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX86968.1 - 0.1 13.1 0.0 0.3 11.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 KFX86968.1 - 0.14 12.4 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L28e PF01778.17 KFX86969.1 - 8.5e-39 132.9 1.7 8.5e-39 132.9 1.7 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KFX86969.1 - 2.2e-31 108.4 10.9 2.2e-31 108.4 10.9 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region Mso1_Sec1_bdg PF14475.6 KFX86969.1 - 5.8e-20 70.6 0.0 5.8e-20 70.6 0.0 2.1 2 0 0 2 2 2 1 Sec1-binding region of Mso1 BUD22 PF09073.10 KFX86969.1 - 7.3e-06 25.6 11.9 1.5e-05 24.6 11.9 1.5 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KFX86969.1 - 0.078 12.7 0.6 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 KFX86969.1 - 0.77 8.3 21.0 1.3 7.5 21.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KFX86969.1 - 4.5 6.6 20.5 6.9 6.0 20.5 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KFX86969.1 - 5.4 5.1 22.2 7.9 4.6 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family Elong_Iki1 PF10483.9 KFX86970.1 - 3.3e-105 351.8 0.0 3.8e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 KFX86971.1 - 2.2e-28 98.1 1.4 4.8e-28 97.0 1.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins AA_permease_2 PF13520.6 KFX86972.1 - 7.3e-24 84.4 22.3 8.7e-24 84.1 22.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX86972.1 - 1.5e-06 27.1 14.8 1.9e-06 26.8 14.8 1.1 1 0 0 1 1 1 1 Amino acid permease zf-UBR PF02207.20 KFX86973.1 - 8.4e-13 48.3 3.2 8.4e-13 48.3 3.2 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ELFV_dehydrog PF00208.21 KFX86974.1 - 4.4e-25 88.8 0.0 7.1e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KFX86974.1 - 9e-15 53.3 0.0 1.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KFX86974.1 - 0.0051 16.7 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain EF-hand_1 PF00036.32 KFX86977.1 - 8.3e-25 84.5 11.7 3.4e-08 32.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFX86977.1 - 7.2e-24 81.6 4.1 5.3e-06 25.9 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFX86977.1 - 1.7e-23 82.8 9.0 1.4e-14 54.3 1.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFX86977.1 - 1.1e-16 59.4 13.3 4.7e-05 22.7 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFX86977.1 - 2.1e-15 56.3 10.8 2.9e-05 23.8 0.8 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFX86977.1 - 7.4e-09 35.5 7.4 0.0019 18.2 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFX86977.1 - 0.00032 21.0 0.6 0.015 15.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFX86977.1 - 0.001 19.4 2.3 0.76 10.1 0.3 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KFX86977.1 - 0.0041 16.0 0.6 0.33 9.7 0.2 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 KFX86977.1 - 0.12 12.3 4.6 0.26 11.2 0.1 3.4 5 0 0 5 5 5 0 EF hand EF-hand_2 PF09068.11 KFX86977.1 - 0.14 12.3 0.0 2.1 8.5 0.0 2.5 3 1 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 KFX86977.1 - 0.39 11.1 2.2 13 6.2 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain Med4 PF10018.9 KFX86978.1 - 3.7e-37 127.9 7.7 7.1e-37 127.0 7.7 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1682 PF07946.14 KFX86978.1 - 0.0028 16.9 2.5 0.0036 16.6 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) TMEM247 PF15444.6 KFX86978.1 - 4.9 7.1 7.8 0.3 11.1 2.4 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 Sas10_Utp3 PF04000.15 KFX86979.1 - 3.5e-18 66.0 1.2 8e-18 64.9 1.2 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.16 KFX86980.1 - 4.6e-204 678.9 2.4 6.4e-204 678.4 2.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pectate_lyase PF03211.13 KFX86981.1 - 5.3e-83 277.6 11.2 8.7e-83 276.9 11.2 1.3 1 0 0 1 1 1 1 Pectate lyase MSP1_C PF07462.11 KFX86981.1 - 0.65 8.6 1.4 0.84 8.3 1.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MFS_1 PF07690.16 KFX86982.1 - 4.7e-36 124.4 25.6 4.7e-36 124.4 25.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily YwiC PF14256.6 KFX86982.1 - 1.9 8.8 9.9 0.11 12.8 0.8 3.0 2 2 0 2 2 2 0 YwiC-like protein Arylsulfotran_2 PF14269.6 KFX86983.1 - 2.1e-21 76.6 0.0 3.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFX86983.1 - 1.7e-20 73.3 0.0 1.6e-09 37.2 0.0 3.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KFX86983.1 - 7.5e-05 22.4 0.0 0.00062 19.4 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain B_lectin PF01453.24 KFX86983.1 - 0.05 14.2 0.1 0.28 11.7 0.1 2.2 2 1 0 2 2 2 0 D-mannose binding lectin Transferase PF02458.15 KFX86984.1 - 6e-07 28.5 0.0 1.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Transferase family Peptidase_M1 PF01433.20 KFX86986.1 - 6.4e-63 212.2 0.0 9.3e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 KFX86986.1 - 1.4e-52 179.3 0.6 2e-52 178.7 0.6 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 KFX86986.1 - 3.5e-42 144.7 0.0 5.4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain NAD_binding_4 PF07993.12 KFX86987.1 - 1e-24 87.1 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFX86987.1 - 6.6e-12 45.4 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX86987.1 - 0.23 10.6 0.3 1.9 7.5 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein DUF302 PF03625.14 KFX86988.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 Amidase PF01425.21 KFX86989.1 - 2.5e-12 46.5 0.0 2.9e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Abhydrolase_1 PF00561.20 KFX86990.1 - 1.4e-17 64.2 0.1 2.9e-17 63.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX86990.1 - 3.1e-11 44.3 0.1 4.2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX86990.1 - 1.1e-10 41.2 0.1 1.2e-09 37.8 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KFX86990.1 - 5e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KFX86990.1 - 0.00023 20.7 0.0 0.08 12.4 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KFX86990.1 - 0.0045 16.6 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 KFX86990.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.6 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 KFX86990.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 KFX86990.1 - 0.05 12.3 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.13 KFX86990.1 - 0.13 11.9 0.0 1.2 8.8 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Glyco_hydro_10 PF00331.20 KFX86991.1 - 4e-101 338.3 0.1 5.1e-101 338.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ADH_zinc_N_2 PF13602.6 KFX86991.1 - 5.5e-10 40.4 0.0 1.2e-05 26.4 0.1 2.7 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX86991.1 - 0.00014 21.8 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_42 PF02449.15 KFX86991.1 - 0.034 13.5 0.1 0.16 11.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase Beta-prism_lec PF16458.5 KFX86991.1 - 0.047 13.7 0.3 0.099 12.6 0.3 1.5 1 0 0 1 1 1 0 Beta-prism lectin MFS_1 PF07690.16 KFX86992.1 - 3e-34 118.5 53.3 4.7e-34 117.9 51.8 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX86992.1 - 6.5e-22 77.7 24.0 8.8e-22 77.3 24.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX86992.1 - 1.6e-12 47.0 17.6 1.6e-12 47.0 17.6 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter Ank_3 PF13606.6 KFX86993.1 - 2.6e-08 33.5 0.1 0.81 10.5 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KFX86993.1 - 6.5e-08 33.0 0.1 0.001 19.6 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX86993.1 - 3.4e-07 30.8 0.0 0.00079 20.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX86993.1 - 0.0014 18.9 0.0 5.9 7.3 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) DNA_pol_B_2 PF03175.13 KFX86994.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral PLA2_B PF01735.18 KFX86995.1 - 3.3e-24 85.2 0.0 1e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain CDC45 PF02724.14 KFX86995.1 - 0.42 8.8 5.2 0.79 7.9 5.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Mitofilin PF09731.9 KFX86995.1 - 5.3 5.8 18.6 0.16 10.8 11.6 1.9 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF1214 PF06742.11 KFX86996.1 - 0.00019 21.8 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) He_PIG PF05345.12 KFX86996.1 - 0.22 11.8 2.5 4.2 7.6 0.3 2.9 2 0 0 2 2 2 0 Putative Ig domain Fungal_trans PF04082.18 KFX86997.1 - 6.5e-68 228.6 0.2 1e-67 228.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX86997.1 - 9.9e-07 28.9 9.6 0.00036 20.8 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX86997.1 - 0.013 15.9 1.1 0.013 15.9 1.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX86997.1 - 0.064 14.1 0.6 0.064 14.1 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DnaJ_C PF01556.18 KFX86998.1 - 6e-37 127.0 0.0 8.9e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFX86998.1 - 2e-22 79.1 1.2 3.9e-22 78.1 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX86998.1 - 2.5e-09 37.3 20.5 5.8e-09 36.2 20.5 1.7 1 0 0 1 1 1 1 DnaJ central domain SAP30_Sin3_bdg PF13867.6 KFX86998.1 - 1.2e-08 35.1 0.1 4.7e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 HypA PF01155.19 KFX86998.1 - 6.8 6.8 10.0 27 4.8 8.3 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Aminotran_5 PF00266.19 KFX87000.1 - 2e-30 106.0 0.0 2.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cwf_Cwc_15 PF04889.12 KFX87002.1 - 2.5 7.8 8.2 3.9 7.1 8.2 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WW PF00397.26 KFX87003.1 - 8.2e-09 35.4 1.9 1.8e-08 34.3 1.9 1.6 1 0 0 1 1 1 1 WW domain WRW PF10206.9 KFX87003.1 - 0.18 12.2 0.3 0.96 9.9 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Voldacs PF03517.13 KFX87004.1 - 1.9e-25 89.6 0.1 1.9e-25 89.6 0.1 2.5 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Peptidase_M18 PF02127.15 KFX87005.1 - 1.5e-130 435.9 0.0 2e-130 435.5 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) tRNA-synt_1e PF01406.19 KFX87005.1 - 9.2e-117 389.7 0.0 1.6e-116 388.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFX87005.1 - 1e-05 24.5 0.0 0.14 10.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KFX87005.1 - 9.2e-05 22.8 0.0 0.00032 21.1 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFX87005.1 - 0.02 13.8 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 KFX87005.1 - 0.032 13.1 5.0 0.078 11.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain CENP-C_C PF11699.8 KFX87007.1 - 5.8e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.12 KFX87007.1 - 0.0026 17.4 0.2 0.0077 15.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) zf-C2H2 PF00096.26 KFX87007.1 - 0.012 16.0 0.8 0.043 14.3 0.8 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFX87007.1 - 0.025 14.6 0.4 0.075 13.0 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cupin_2 PF07883.11 KFX87007.1 - 0.071 12.8 1.3 0.091 12.5 0.1 1.8 2 0 0 2 2 2 0 Cupin domain zf-C2H2_4 PF13894.6 KFX87007.1 - 0.097 13.6 0.7 0.31 12.0 0.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger IPP-2 PF04979.14 KFX87008.1 - 1.3e-22 80.9 6.1 3.1e-22 79.7 6.1 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) NmrA PF05368.13 KFX87009.1 - 2.3e-18 66.6 0.1 3e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX87009.1 - 6.4e-08 32.7 0.0 4.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFX87009.1 - 0.00071 19.1 0.0 0.0054 16.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX87009.1 - 0.0029 17.5 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX87009.1 - 0.058 12.5 0.2 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KFX87009.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KFX87010.1 - 1.3e-41 141.9 0.0 1.9e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX87010.1 - 1.4e-10 40.9 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX87010.1 - 4.9e-09 36.5 0.1 1.9e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX87010.1 - 6.6e-05 23.4 0.2 0.00011 22.7 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KFX87010.1 - 0.0026 18.5 0.0 0.0069 17.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.21 KFX87010.1 - 0.016 15.6 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily IlvN PF07991.12 KFX87010.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KFX87010.1 - 0.08 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lipase_GDSL_2 PF13472.6 KFX87011.1 - 2.1e-16 60.8 3.0 2.6e-16 60.6 3.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX87011.1 - 7.3e-09 35.9 0.2 9.3e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 KFX87011.1 - 0.19 11.4 1.6 1.1 8.9 0.3 2.2 2 1 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX K_channel_TID PF07941.11 KFX87011.1 - 8.6 6.9 8.4 0.41 11.1 1.2 2.5 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain EXS PF03124.14 KFX87012.1 - 1.3e-101 340.2 28.3 1.6e-101 339.9 28.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFX87012.1 - 7.2e-81 273.1 3.6 7.2e-81 273.1 3.6 2.2 2 0 0 2 2 2 1 SPX domain Paramyx_P_V_C PF03210.13 KFX87012.1 - 0.018 14.8 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF883 PF05957.13 KFX87012.1 - 0.1 13.2 0.0 0.33 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) An_peroxidase PF03098.15 KFX87013.1 - 2e-40 138.9 0.0 1.4e-28 99.8 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KFX87013.1 - 1.5e-11 43.7 0.0 9.6e-08 31.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 tRNA_int_endo PF01974.17 KFX87014.1 - 9.5e-20 70.5 0.3 2.3e-19 69.2 0.3 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KFX87014.1 - 9.2e-05 22.0 0.0 0.046 13.4 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF3759 PF12585.8 KFX87017.1 - 4.3e-37 126.0 9.4 6.5e-37 125.5 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 KFX87017.1 - 2.1 9.0 13.2 3.1 8.4 10.3 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) CoaE PF01121.20 KFX87018.1 - 2.2e-42 144.7 0.0 3.4e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase Peptidase_M16_M PF16187.5 KFX87019.1 - 5.8e-99 330.9 0.7 9.2e-99 330.2 0.7 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KFX87019.1 - 2e-34 118.8 1.1 1.1e-33 116.3 0.2 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFX87019.1 - 2.9e-32 112.2 0.1 3.3e-19 69.6 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain MPP6 PF10175.9 KFX87020.1 - 1.1e-09 38.9 13.1 1.5e-05 25.5 4.5 3.0 2 1 1 3 3 3 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KFX87020.1 - 8.3e-08 32.0 1.7 1.5e-07 31.1 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop53 PF07767.11 KFX87020.1 - 0.00044 19.8 7.5 0.00044 19.8 7.5 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KFX87020.1 - 0.05 11.9 8.7 0.075 11.3 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 KFX87020.1 - 0.059 13.5 17.1 0.019 15.1 12.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein zf-CCHC_3 PF13917.6 KFX87020.1 - 0.11 12.4 0.4 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.12 KFX87020.1 - 0.2 11.3 22.2 0.55 9.9 22.3 1.7 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CHCC PF10276.9 KFX87021.1 - 8.5e-17 60.9 1.7 1.7e-16 59.9 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain Glyco_transf_21 PF13506.6 KFX87022.1 - 2.5e-13 49.9 0.0 3.2e-06 26.7 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFX87022.1 - 8.6e-07 29.1 0.0 2.4e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX87022.1 - 0.0011 18.8 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Ntox46 PF15538.6 KFX87022.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 46 HCO3_cotransp PF00955.21 KFX87023.1 - 2e-83 280.9 15.6 4.7e-44 151.1 8.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family Glyco_hydro_cc PF11790.8 KFX87023.1 - 4.1e-14 52.7 0.0 7.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MOSC PF03473.17 KFX87024.1 - 2.2e-27 95.7 0.0 3.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFX87024.1 - 2.5e-12 46.7 0.0 5.9e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain zf-RING_2 PF13639.6 KFX87025.1 - 2e-12 47.2 5.1 3.7e-12 46.4 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX87025.1 - 4.4e-09 36.0 4.0 9.3e-09 35.0 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX87025.1 - 4.6e-09 36.4 2.0 1e-08 35.3 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 KFX87025.1 - 4.7e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 KFX87025.1 - 1.2e-08 34.6 2.7 2.3e-08 33.8 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX87025.1 - 1.5e-08 34.2 2.2 1.5e-08 34.2 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFX87025.1 - 2.2e-06 27.5 2.0 2.2e-06 27.5 2.0 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFX87025.1 - 3.5e-05 23.6 2.8 3.5e-05 23.6 2.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX87025.1 - 3.6e-05 23.7 2.0 0.00029 20.8 2.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFX87025.1 - 0.0012 18.8 0.8 0.0029 17.6 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KFX87025.1 - 0.014 15.2 2.9 0.032 14.1 2.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RRP14 PF15459.6 KFX87025.1 - 0.039 14.5 1.2 0.039 14.5 1.2 2.2 2 0 0 2 2 1 0 60S ribosome biogenesis protein Rrp14 Zn_ribbon_17 PF17120.5 KFX87025.1 - 0.062 12.9 3.1 0.15 11.7 3.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFX87025.1 - 0.2 11.9 2.1 0.5 10.6 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFX87025.1 - 0.2 12.0 3.0 0.36 11.2 3.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KFX87025.1 - 0.41 10.5 2.6 0.84 9.5 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFX87025.1 - 0.6 10.3 3.2 1.2 9.3 3.2 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KFX87025.1 - 0.8 9.6 2.4 1.6 8.7 2.4 1.5 1 0 0 1 1 1 0 PHD-finger ACPS PF01648.20 KFX87026.1 - 9.5e-08 32.2 0.1 6.6e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_61 PF03443.14 KFX87027.1 - 9.7e-54 182.4 0.0 1.2e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4360 PF14273.6 KFX87028.1 - 2.9e-61 206.4 2.2 7.8e-61 205.0 2.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Rio2_N PF09202.11 KFX87029.1 - 1.3e-29 102.2 0.1 1.9e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Rio2, N-terminal RIO1 PF01163.22 KFX87029.1 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.4 2 0 0 2 2 2 1 RIO1 family RPN1_RPN2_N PF17781.1 KFX87030.1 - 2.2e-112 375.5 1.9 3.5e-112 374.8 1.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFX87030.1 - 1.6e-29 101.7 0.4 5.2e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFX87030.1 - 2e-20 72.1 16.0 1.8e-06 28.1 0.8 8.0 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFX87030.1 - 1.1e-07 32.1 0.7 0.0051 17.2 0.1 4.4 4 1 1 5 5 5 3 HEAT repeats PPTA PF01239.22 KFX87031.1 - 0.19 11.5 5.1 0.39 10.5 5.1 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Mlh1_C PF16413.5 KFX87032.1 - 4.6e-99 331.2 0.0 6.8e-99 330.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFX87032.1 - 1.4e-32 111.9 0.1 3.2e-32 110.7 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFX87032.1 - 2.7e-15 56.4 0.0 6.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFX87032.1 - 7.7e-07 29.6 0.0 2.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_8 PF13905.6 KFX87032.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like zf-CRD PF17979.1 KFX87033.1 - 0.00026 21.1 4.4 0.00033 20.8 4.4 1.2 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions DHHA2 PF02833.14 KFX87034.1 - 5.7e-37 127.1 0.1 8.8e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KFX87034.1 - 1.5e-12 47.6 0.0 5.5e-12 45.8 0.0 1.8 1 1 1 2 2 2 1 DHH family FMO-like PF00743.19 KFX87035.1 - 1.7e-57 195.1 0.0 2.5e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like AATase PF07247.12 KFX87035.1 - 5.3e-16 58.2 0.1 6.5e-10 38.2 0.4 3.5 2 2 0 2 2 2 2 Alcohol acetyltransferase Pyr_redox_3 PF13738.6 KFX87035.1 - 5.8e-14 52.0 0.0 9.4e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX87035.1 - 1.6e-10 40.7 0.0 4e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX87035.1 - 1.2e-07 31.8 0.0 3.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX87035.1 - 1.3e-05 24.5 0.7 0.00067 18.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFX87035.1 - 0.00021 21.3 0.1 0.003 17.6 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding WES_acyltransf PF03007.16 KFX87035.1 - 0.00021 21.2 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Pyr_redox PF00070.27 KFX87035.1 - 0.00047 20.7 0.0 0.15 12.6 0.0 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX87035.1 - 0.002 17.4 0.0 0.0057 15.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KFX87035.1 - 0.0025 17.5 0.0 0.54 9.8 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Condensation PF00668.20 KFX87035.1 - 0.0066 15.2 0.6 0.028 13.1 0.0 2.0 2 0 0 2 2 2 1 Condensation domain NAD_binding_7 PF13241.6 KFX87035.1 - 0.017 15.5 0.0 3.5 8.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX87035.1 - 0.028 13.8 0.0 0.71 9.2 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p6 PF17548.2 KFX87035.1 - 0.12 12.3 0.1 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 Histone-like Protein p6 Glu_dehyd_C PF16912.5 KFX87035.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GCP_C_terminal PF04130.13 KFX87036.1 - 2.1e-20 73.4 0.0 6.3e-20 71.9 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFX87036.1 - 2.7e-18 66.6 1.6 3.4e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal HTH_ParB PF17762.1 KFX87036.1 - 0.19 11.5 1.4 17 5.3 0.1 2.5 2 0 0 2 2 2 0 HTH domain found in ParB protein ThiF PF00899.21 KFX87038.1 - 2.7e-109 364.2 0.0 5.2e-73 245.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFX87038.1 - 1.8e-93 313.1 0.2 2.6e-93 312.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFX87038.1 - 1.9e-30 104.8 0.1 3.9e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KFX87038.1 - 8.5e-29 100.1 0.0 1.8e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KFX87038.1 - 2.4e-25 88.5 0.2 6.6e-25 87.1 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KFX87038.1 - 0.013 15.6 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rad60-SLD_2 PF13881.6 KFX87039.1 - 7.6e-14 51.8 0.1 2.2e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFX87039.1 - 1.7e-05 24.5 0.0 4.1e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 KFX87039.1 - 0.00024 21.6 0.1 0.00067 20.2 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF4592 PF15262.6 KFX87039.1 - 0.037 14.7 3.9 0.052 14.2 2.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) AMP-binding PF00501.28 KFX87040.1 - 9.9e-78 261.6 0.0 1.2e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX87040.1 - 4.3e-12 46.9 0.2 1.1e-11 45.6 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KFX87041.1 - 6.8e-23 81.9 0.1 2.1e-22 80.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RPA_interact_C PF14768.6 KFX87041.1 - 0.015 15.8 1.6 0.04 14.5 1.6 1.7 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF2387 PF09526.10 KFX87041.1 - 0.13 12.5 1.1 0.52 10.5 1.1 2.0 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) AIRC PF00731.20 KFX87042.1 - 2.8e-57 192.4 2.0 6.7e-57 191.2 2.0 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KFX87042.1 - 4.1e-54 182.7 0.0 8.3e-54 181.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KFX87042.1 - 5.8e-20 70.7 0.1 1.5e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KFX87042.1 - 2.3e-07 30.6 0.0 4.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Radical_SAM PF04055.21 KFX87042.1 - 0.0029 18.0 0.0 4.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily Dala_Dala_lig_C PF07478.13 KFX87042.1 - 0.0094 15.5 0.0 0.074 12.6 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus APH PF01636.23 KFX87043.1 - 3.5e-11 43.5 0.3 9.2e-11 42.1 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX87043.1 - 0.0004 20.0 0.0 0.0047 16.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KFX87043.1 - 0.00095 18.8 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFX87043.1 - 0.0025 17.2 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.21 KFX87044.1 - 1e-07 31.7 0.0 1.6e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX87044.1 - 1.4e-06 27.6 0.0 2.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFX87044.1 - 0.0045 16.5 0.1 2.8 7.4 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase 3Beta_HSD PF01073.19 KFX87044.1 - 0.005 15.9 0.0 0.01 14.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX87044.1 - 0.014 14.8 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PI3_PI4_kinase PF00454.27 KFX87045.1 - 3.2e-53 181.1 0.0 6e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.7 KFX87045.1 - 1.8e-47 159.8 0.0 1.3e-10 41.7 0.0 6.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) FAT PF02259.23 KFX87045.1 - 4.7e-41 141.1 6.0 9.6e-41 140.1 6.0 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KFX87045.1 - 7.9e-33 112.4 0.5 1.5e-31 108.3 0.1 2.9 2 0 0 2 2 2 1 UME (NUC010) domain Ank_5 PF13857.6 KFX87045.1 - 1.2e-27 95.6 0.1 2.2e-06 27.8 0.0 7.6 5 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX87045.1 - 1.1e-25 89.7 0.3 0.00035 21.1 0.0 7.7 3 1 5 9 9 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX87045.1 - 9.8e-23 77.8 0.0 0.039 14.5 0.0 10.9 11 0 0 11 11 9 4 Ankyrin repeat Ank PF00023.30 KFX87045.1 - 1.5e-17 63.2 0.0 0.14 12.6 0.0 9.5 9 1 0 9 9 8 3 Ankyrin repeat NACHT PF05729.12 KFX87045.1 - 8.4e-12 45.3 0.0 3.3e-11 43.4 0.0 2.2 1 0 0 1 1 1 1 NACHT domain FATC PF02260.20 KFX87045.1 - 1.8e-06 27.7 0.0 6.5e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 FATC domain AAA_16 PF13191.6 KFX87045.1 - 3.3e-06 27.6 0.0 3.3e-05 24.3 0.0 2.8 2 0 0 2 2 1 1 AAA ATPase domain DUF676 PF05057.14 KFX87045.1 - 0.0011 18.6 0.0 0.015 14.8 0.0 2.6 2 1 1 3 3 3 1 Putative serine esterase (DUF676) TPR_19 PF14559.6 KFX87045.1 - 0.0019 18.7 1.1 0.043 14.3 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 KFX87045.1 - 0.0038 17.5 0.0 0.052 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain LIDHydrolase PF10230.9 KFX87045.1 - 0.012 15.2 0.0 1.5 8.3 0.0 3.0 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase Cutinase PF01083.22 KFX87045.1 - 0.075 13.0 0.0 1.1 9.2 0.0 2.2 1 1 0 2 2 2 0 Cutinase COX16 PF14138.6 KFX87046.1 - 3.7e-34 117.1 0.1 4.8e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 OppC_N PF12911.7 KFX87046.1 - 0.076 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Acetyltransf_1 PF00583.25 KFX87047.1 - 2.1e-10 40.9 0.0 2.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX87047.1 - 4.4e-08 33.1 0.0 6.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX87047.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX87047.1 - 7.4e-05 22.6 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KFX87047.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 KFX87047.1 - 0.041 14.0 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX87047.1 - 0.053 13.6 0.0 0.099 12.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX87047.1 - 0.16 12.1 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase BcrAD_BadFG PF01869.20 KFX87049.1 - 2.2e-16 60.2 0.2 3.6e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KFX87049.1 - 0.00012 22.1 1.0 0.0011 19.0 0.1 3.2 3 1 0 3 3 3 1 SIS domain SIS PF01380.22 KFX87049.1 - 0.00039 20.3 0.6 0.0023 17.8 0.0 2.4 2 1 0 2 2 2 1 SIS domain UNC-93 PF05978.16 KFX87050.1 - 2.2e-08 33.9 5.7 2.2e-08 33.9 5.7 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFX87050.1 - 9.4e-08 31.4 40.2 9.4e-08 31.4 40.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily EXS PF03124.14 KFX87050.1 - 0.45 9.8 5.9 0.082 12.2 1.9 1.8 2 0 0 2 2 2 0 EXS family Beta-lactamase PF00144.24 KFX87051.1 - 9.8e-52 176.2 0.0 1.3e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX87051.1 - 0.00051 19.5 0.8 0.0029 17.1 0.2 2.3 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KFX87051.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family DIM1 PF02966.16 KFX87052.1 - 5.3e-67 223.6 0.5 7.8e-67 223.1 0.5 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF218 PF02698.17 KFX87052.1 - 2.8e-22 79.1 0.0 5.3e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain DUF2439 PF10382.9 KFX87053.1 - 4.4e-27 94.2 0.1 9e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Podoplanin PF05808.11 KFX87059.1 - 0.0051 16.9 0.1 0.01 15.9 0.1 1.4 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 KFX87059.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF347 PF03988.12 KFX87059.1 - 0.23 11.7 0.5 0.55 10.5 0.5 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) VSP PF03302.13 KFX87059.1 - 1.6 7.5 18.3 0.056 12.3 4.2 2.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein BAR_2 PF10455.9 KFX87061.1 - 3.9e-26 91.9 0.5 4.4e-26 91.7 0.5 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFX87061.1 - 8e-07 28.9 0.4 9.1e-07 28.8 0.4 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KFX87061.1 - 0.0079 15.8 0.4 0.011 15.4 0.4 1.2 1 0 0 1 1 1 1 Arfaptin-like domain HD_3 PF13023.6 KFX87063.1 - 6.3e-48 162.8 0.0 1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFX87063.1 - 1.6e-08 34.5 0.0 3.9e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme Glyco_hydro_3_C PF01915.22 KFX87065.1 - 1.9e-60 204.3 0.0 4.2e-60 203.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX87065.1 - 8.9e-46 156.7 0.0 1.4e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX87065.1 - 2e-25 88.6 1.6 5e-25 87.4 1.6 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KFX87065.1 - 3.4e-15 56.1 0.0 6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Transketolase_N PF00456.21 KFX87066.1 - 8.3e-151 501.6 0.3 1.1e-150 501.3 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFX87066.1 - 1.7e-44 151.6 0.0 2.8e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFX87066.1 - 3.8e-12 46.2 0.0 9.1e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Beta_elim_lyase PF01212.21 KFX87066.1 - 0.047 13.0 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ank_2 PF12796.7 KFX87067.1 - 7.6e-10 39.3 0.0 7.1e-05 23.3 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) NACHT PF05729.12 KFX87067.1 - 9.2e-10 38.7 0.2 2.3e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX87067.1 - 4.2e-08 33.8 1.3 4.7e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.6 KFX87067.1 - 3.9e-07 29.9 1.3 0.0027 18.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFX87067.1 - 2.6e-06 27.9 2.8 0.45 11.2 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX87067.1 - 6.7e-05 23.1 1.0 0.76 10.2 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KFX87067.1 - 0.00018 20.9 1.1 0.098 11.9 0.4 2.4 2 0 0 2 2 2 2 KAP family P-loop domain Helo_like_N PF17111.5 KFX87067.1 - 0.00089 18.7 0.0 0.0042 16.5 0.0 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 KFX87067.1 - 0.0093 16.4 0.9 0.72 10.4 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat Biotin_lipoyl PF00364.22 KFX87069.1 - 3.1e-18 65.4 1.1 4.1e-18 65.0 1.1 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KFX87069.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Biotin-lipoyl like Sec7 PF01369.20 KFX87070.1 - 5.8e-71 238.0 0.3 5.8e-71 238.0 0.3 3.1 3 1 1 4 4 4 1 Sec7 domain Sec7_N PF12783.7 KFX87070.1 - 1.8e-40 138.4 4.0 1.8e-40 138.4 4.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFX87070.1 - 2.3e-31 107.5 7.9 2e-30 104.5 0.1 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 KFX87070.1 - 1.4e-19 70.4 0.5 1.4e-19 70.4 0.5 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 NAD_binding_7 PF13241.6 KFX87071.1 - 1.6e-32 112.0 0.1 2.5e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KFX87071.1 - 1.8e-25 88.4 0.0 2.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KFX87071.1 - 9.8e-14 50.5 0.0 1.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KFX87071.1 - 0.00053 19.3 0.0 0.00069 19.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX87071.1 - 0.0045 17.0 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KFX87071.1 - 0.045 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFX87071.1 - 0.2 11.0 0.6 1.7 7.9 0.0 2.0 1 1 1 2 2 2 0 ThiF family ThrE PF06738.12 KFX87073.1 - 1.7e-17 63.6 25.4 2.9e-14 53.0 5.2 2.5 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFX87073.1 - 4.1e-11 43.1 19.8 8.9e-10 38.8 8.0 2.4 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE MIG-14_Wnt-bd PF06664.12 KFX87073.1 - 0.14 11.4 8.3 0.32 10.2 8.3 1.7 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF373 PF04123.13 KFX87073.1 - 3 7.2 6.9 4.8 6.5 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Methyltransf_23 PF13489.6 KFX87074.1 - 3.3e-22 79.1 0.1 8.5e-22 77.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87074.1 - 2.3e-11 44.2 0.0 4.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX87074.1 - 4.8e-09 36.8 0.0 9.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87074.1 - 2.5e-07 30.6 0.0 3.6e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX87074.1 - 3.1e-06 27.9 0.0 1.7e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX87074.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KFX87074.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFX87074.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KFX87074.1 - 0.048 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KFX87074.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX87074.1 - 0.14 11.4 0.0 1.3 8.3 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.19 KFX87075.1 - 7.2e-21 74.8 0.5 2.8e-10 40.0 0.1 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KFX87075.1 - 2.9e-06 27.1 0.0 4.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX87075.1 - 1.9e-05 24.8 0.1 3.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX87075.1 - 0.0063 17.0 0.1 0.41 11.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX87075.1 - 0.0098 15.0 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX87075.1 - 0.088 12.0 0.1 0.32 10.2 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX87075.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NEMO PF11577.8 KFX87075.1 - 0.14 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO DUF2370 PF10176.9 KFX87077.1 - 1.6e-83 279.8 6.0 2.5e-71 240.0 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) SEEEED PF14797.6 KFX87077.1 - 0.055 13.6 5.6 0.1 12.8 5.6 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DNA_methylase PF00145.17 KFX87078.1 - 3.4e-31 108.8 0.0 8.4e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KFX87078.1 - 3.9e-05 23.5 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 BAH domain MFS_1 PF07690.16 KFX87079.1 - 1.5e-30 106.3 24.8 1.5e-30 106.3 24.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KFX87079.1 - 0.046 14.0 0.4 0.046 14.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) CECR6_TMEM121 PF14997.6 KFX87079.1 - 0.052 13.4 1.3 0.078 12.8 0.1 1.9 2 0 0 2 2 2 0 CECR6/TMEM121 family AfaD PF05775.12 KFX87079.1 - 0.14 12.6 0.1 0.45 11.0 0.0 1.8 2 0 0 2 2 2 0 Enterobacteria AfaD invasin protein NEMP PF10225.9 KFX87079.1 - 0.35 10.5 7.1 0.84 9.3 7.1 1.6 1 0 0 1 1 1 0 NEMP family Glyco_tranf_2_4 PF13704.6 KFX87080.1 - 1e-07 32.4 0.3 3.7e-07 30.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KFX87080.1 - 2e-06 27.7 0.5 5.2e-06 26.3 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Pan3_PK PF18101.1 KFX87081.1 - 0.052 13.5 0.3 0.87 9.6 0.0 2.7 3 0 0 3 3 3 0 Pan3 Pseudokinase domain Fungal_trans PF04082.18 KFX87082.1 - 0.017 14.1 8.7 0.019 14.0 1.4 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.20 KFX87083.1 - 5.7e-87 292.1 1.1 7e-87 291.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFX87083.1 - 3.9e-34 117.9 0.2 6.8e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sortilin-Vps10 PF15902.5 KFX87083.1 - 0.0025 16.7 0.1 0.088 11.6 0.0 2.2 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 KFX87083.1 - 0.032 13.6 0.0 0.072 12.4 0.0 1.5 1 1 0 1 1 1 0 BNR repeat-like domain CHB_HEX_C PF03174.13 KFX87083.1 - 0.035 14.1 0.1 0.98 9.4 0.0 2.6 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Sugar_tr PF00083.24 KFX87084.1 - 8.3e-128 427.1 23.5 9.6e-128 426.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87084.1 - 7.3e-22 77.8 27.8 7.3e-22 77.8 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GDP_Man_Dehyd PF16363.5 KFX87084.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 KFX87085.1 - 3.7e-71 240.3 13.0 4.7e-45 154.3 0.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX87085.1 - 2.3e-14 53.1 33.2 9.3e-12 44.5 9.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 KFX87085.1 - 6.3 6.9 6.5 11 6.1 0.2 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C TBP PF00352.21 KFX87086.1 - 3.1e-67 222.5 0.1 1.6e-32 111.3 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFX87086.1 - 0.00023 21.2 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Complex1_LYR PF05347.15 KFX87087.1 - 0.0002 21.3 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HTH_16 PF12645.7 KFX87087.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3533 PF12051.8 KFX87088.1 - 1.1e-61 208.8 21.1 1.5e-32 113.0 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3533) Ank_4 PF13637.6 KFX87088.1 - 7e-14 52.0 1.2 5.6e-09 36.4 0.5 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX87088.1 - 1.6e-10 41.5 0.1 0.00051 20.6 0.2 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) APH PF01636.23 KFX87088.1 - 7.5e-09 35.9 0.1 5.2e-08 33.1 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_3 PF13606.6 KFX87088.1 - 1.4e-08 34.3 1.9 0.036 14.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFX87088.1 - 1.1e-07 32.0 2.6 0.071 13.5 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX87088.1 - 1.4e-07 31.7 1.7 0.52 10.8 0.5 4.7 4 0 0 4 4 4 2 Ankyrin repeat Choline_kinase PF01633.20 KFX87088.1 - 0.0044 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase KilA-N PF04383.13 KFX87088.1 - 0.0048 16.7 0.3 0.038 13.8 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain bZIP_1 PF00170.21 KFX87089.1 - 2.1e-05 24.5 11.1 4e-05 23.6 11.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KFX87089.1 - 0.18 12.5 0.9 0.38 11.4 0.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA BRE1 PF08647.11 KFX87089.1 - 0.31 11.2 6.1 0.22 11.6 4.3 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 KFX87089.1 - 0.36 10.9 13.0 6.1 7.0 13.0 2.3 1 1 0 1 1 1 0 Basic region leucine zipper TFB6 PF17110.5 KFX87090.1 - 2.4e-56 190.1 0.0 2.7e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Pes-10 PF07149.11 KFX87090.1 - 0.26 10.3 3.6 0.32 10.0 3.6 1.1 1 0 0 1 1 1 0 Pes-10 Pro_isomerase PF00160.21 KFX87091.1 - 9.1e-35 120.3 0.0 1.4e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFX87091.1 - 2.9e-15 55.8 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX87091.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 KFX87092.1 - 1.7e-07 31.3 6.7 2.9e-07 30.5 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 KFX87094.1 - 3.6e-34 116.5 0.1 7.6e-34 115.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 KFX87095.1 - 5.1e-23 81.7 0.0 3e-21 75.9 0.0 2.8 3 0 0 3 3 3 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFX87095.1 - 0.00045 20.1 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX87095.1 - 0.00068 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KFX87095.1 - 0.0084 15.9 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX87095.1 - 0.058 12.9 0.1 0.3 10.6 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KFX87095.1 - 0.11 13.2 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-MIZ PF02891.20 KFX87096.1 - 6.3e-11 41.8 0.3 1.2e-10 40.9 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 KFX87096.1 - 0.00053 20.3 0.0 0.0016 18.8 0.0 1.9 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 KFX87096.1 - 0.0049 16.7 0.3 0.021 14.6 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LexA_DNA_bind PF01726.16 KFX87096.1 - 0.021 14.6 0.0 4 7.3 0.0 2.8 2 0 0 2 2 2 0 LexA DNA binding domain Pkinase PF00069.25 KFX87098.1 - 5.7e-44 150.5 0.0 2.3e-29 102.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87098.1 - 6.8e-24 84.6 0.0 4.7e-14 52.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KFX87098.1 - 7e-06 25.6 0.0 0.00021 20.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFX87098.1 - 0.0071 16.3 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.12 KFX87099.1 - 3.2e-26 92.0 0.0 3.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFX87099.1 - 0.0061 16.7 0.2 0.0087 16.2 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peroxin-3 PF04882.12 KFX87100.1 - 1.1e-172 575.3 0.1 1.2e-172 575.1 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KFX87101.1 - 6.3e-41 139.9 0.2 1.3e-40 138.9 0.2 1.5 1 0 0 1 1 1 1 Autophagy-related protein 101 AA_kinase PF00696.28 KFX87101.1 - 2.7e-38 131.9 0.1 6.1e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KFX87101.1 - 8.5e-15 54.2 0.8 7.8e-07 28.8 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KFX87101.1 - 5.6e-10 38.9 2.7 3.5e-08 33.1 0.3 2.6 2 0 0 2 2 2 2 ACT domain Xan_ur_permease PF00860.20 KFX87102.1 - 1.2e-15 57.1 20.8 6.9e-14 51.3 20.8 3.0 1 1 0 1 1 1 1 Permease family Kin17_mid PF10357.9 KFX87103.1 - 2.3e-52 176.2 1.2 2.3e-52 176.2 1.2 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KFX87103.1 - 2e-05 24.8 3.4 5e-05 23.5 3.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX87103.1 - 6e-05 23.2 2.2 6e-05 23.2 2.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFX87103.1 - 0.017 15.5 0.4 0.017 15.5 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Spt4 PF06093.13 KFX87104.1 - 1.2e-31 108.6 0.4 1.5e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PPP5 PF08321.12 KFX87105.1 - 1.8e-32 111.5 0.4 8.2e-32 109.4 0.0 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KFX87105.1 - 6.5e-32 111.7 0.0 9.9e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KFX87105.1 - 4.4e-15 54.8 1.6 0.00084 19.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFX87105.1 - 1.6e-10 40.5 4.8 4.7e-05 23.0 0.3 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 KFX87105.1 - 2e-10 40.3 0.6 0.0002 21.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX87105.1 - 5.1e-09 35.6 6.7 0.0066 16.5 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX87105.1 - 0.00051 20.5 1.0 2.4 8.7 0.0 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX87105.1 - 0.0013 18.9 0.0 0.094 12.9 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX87105.1 - 0.0022 18.7 1.1 2.8 9.0 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX87105.1 - 0.0039 17.7 0.2 3.5 8.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX87105.1 - 0.022 14.9 3.4 5.2 7.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX87105.1 - 0.028 15.1 3.2 1.1 9.9 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX87105.1 - 0.074 13.1 0.4 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Es2 PF09751.9 KFX87107.1 - 9.8e-135 450.6 1.2 9.8e-135 450.6 1.2 1.8 2 0 0 2 2 2 1 Nuclear protein Es2 ABC1 PF03109.16 KFX87107.1 - 1.2e-32 112.6 0.0 2.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RRP36 PF06102.12 KFX87108.1 - 3.3e-53 180.0 29.4 3.3e-53 180.0 29.4 2.2 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2383 PF09537.10 KFX87108.1 - 0.12 12.7 9.3 0.094 13.1 4.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) NIF PF03031.18 KFX87109.1 - 6.9e-18 64.9 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.19 KFX87110.1 - 1.4e-44 150.5 0.1 2.6e-44 149.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KFX87110.1 - 1.5e-16 60.4 0.1 3e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX87110.1 - 1.1e-11 44.9 0.1 4.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX87110.1 - 2.8e-10 40.1 0.1 5.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX87110.1 - 1e-06 28.8 0.1 4.3e-06 26.9 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX87110.1 - 0.00022 21.5 0.0 0.00048 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX87110.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.19 KFX87111.1 - 8.5e-42 142.5 0.6 1.3e-41 141.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRF1 PF07741.13 KFX87112.1 - 0.065 13.6 0.8 0.16 12.4 0.2 2.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain EF-hand_1 PF00036.32 KFX87113.1 - 7.2e-27 90.9 9.8 3.4e-07 29.3 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFX87113.1 - 1e-23 83.6 13.4 4.7e-14 52.6 1.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFX87113.1 - 1.9e-21 74.1 5.1 2e-05 24.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX87113.1 - 7.8e-20 69.4 8.8 1.1e-06 27.9 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFX87113.1 - 2.2e-14 53.0 8.6 3.7e-05 23.5 0.4 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFX87113.1 - 8.5e-07 29.3 0.0 0.0034 17.7 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFX87113.1 - 2.6e-06 27.3 7.6 0.0028 17.6 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFX87113.1 - 0.023 14.9 0.7 0.1 12.8 0.7 2.2 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 KFX87114.1 - 8e-22 78.3 5.1 8e-22 78.3 5.1 2.0 2 1 0 2 2 2 1 Enhancer of polycomb-like SET PF00856.28 KFX87115.1 - 2.6e-21 76.7 0.1 5.8e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KFX87115.1 - 1.3e-10 42.1 0.5 1.3e-10 42.1 0.5 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF4484 PF14831.6 KFX87115.1 - 0.12 12.4 2.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DAO PF01266.24 KFX87117.1 - 2.1e-22 80.2 0.0 2.3e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX87117.1 - 3.9e-05 23.0 0.1 6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX87117.1 - 0.00018 22.0 0.1 0.00042 20.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX87117.1 - 0.00041 20.5 0.5 0.001 19.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX87117.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KFX87117.1 - 0.0041 16.3 0.1 0.0051 15.9 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KFX87117.1 - 0.0063 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFX87117.1 - 0.022 14.0 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX87117.1 - 0.023 14.3 0.2 0.044 13.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KFX87117.1 - 0.025 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 KFX87117.1 - 0.028 13.1 0.1 0.038 12.7 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KFX87117.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5510 PF17629.2 KFX87117.1 - 0.096 12.6 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5510) AlaDh_PNT_C PF01262.21 KFX87117.1 - 0.19 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFX87117.1 - 0.22 10.7 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_61 PF03443.14 KFX87118.1 - 2.1e-55 187.8 0.0 2.5e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gpr1_Fun34_YaaH PF01184.19 KFX87119.1 - 1.1e-92 309.3 20.6 1.3e-92 309.1 20.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2948 PF11164.8 KFX87119.1 - 0.12 12.4 0.1 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) DUF202 PF02656.15 KFX87119.1 - 4.2 7.9 11.5 11 6.6 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) ATP-synt_DE_N PF02823.16 KFX87122.1 - 1.7e-14 53.5 0.0 2.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain AKNA PF12443.8 KFX87125.1 - 6.6 7.5 6.6 0.58 10.8 0.2 2.6 3 0 0 3 3 3 0 AT-hook-containing transcription factor HAD_2 PF13419.6 KFX87126.1 - 2.3e-12 47.3 0.0 2.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX87126.1 - 3.1e-09 37.4 0.0 3.2e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX87126.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Med21 PF11221.8 KFX87127.1 - 7.6e-46 155.9 4.1 8.8e-46 155.7 4.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex BRE1 PF08647.11 KFX87127.1 - 0.0045 17.0 3.2 0.0045 17.0 3.2 1.8 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase GAS PF13851.6 KFX87127.1 - 0.0052 16.1 6.5 0.41 10.0 5.0 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 KFX87127.1 - 0.019 15.1 4.8 0.029 14.5 3.5 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 KFX87127.1 - 0.021 14.3 5.6 0.028 13.9 5.6 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Herpes_UL6 PF01763.16 KFX87127.1 - 0.073 11.6 1.8 0.095 11.2 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4574 PF15141.6 KFX87127.1 - 1.3 8.9 4.1 2.2 8.2 3.9 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2034 PF10356.9 KFX87128.1 - 1.1e-30 106.4 0.0 9.6e-15 54.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KFX87128.1 - 2.9e-09 37.0 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF4365 PF14280.6 KFX87128.1 - 0.0037 17.2 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4365) ResIII PF04851.15 KFX87130.1 - 3.2e-22 79.3 0.0 1.2e-21 77.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX87130.1 - 1.4e-15 57.6 0.0 1.4e-13 51.2 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX87130.1 - 4.9e-10 39.4 0.0 3.9e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFX87130.1 - 0.00028 20.6 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SwrA PF17423.2 KFX87130.1 - 0.022 14.8 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 Swarming motility protein DUF2075 PF09848.9 KFX87130.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 KFX87130.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TatD_DNase PF01026.21 KFX87131.1 - 1.2e-31 110.1 0.0 1.9e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase RGP PF03214.13 KFX87131.1 - 0.16 11.1 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 Reversibly glycosylated polypeptide Cullin PF00888.22 KFX87132.1 - 1e-195 652.0 11.5 1.1e-195 651.8 11.5 1.0 1 0 0 1 1 1 1 Cullin family AnfG_VnfG PF03139.15 KFX87132.1 - 0.021 14.9 3.8 0.16 12.1 0.9 3.0 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Aldo_ket_red PF00248.21 KFX87133.1 - 2.6e-63 214.0 0.0 3e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family He_PIG PF05345.12 KFX87134.1 - 4.8e-16 58.7 16.0 2.1e-05 24.6 2.9 4.9 4 0 0 4 4 4 4 Putative Ig domain Sarcoglycan_2 PF05510.13 KFX87134.1 - 0.0063 15.3 0.1 1.4 7.6 0.0 2.7 3 0 0 3 3 3 2 Sarcoglycan alpha/epsilon Methyltransf_16 PF10294.9 KFX87135.1 - 3.1e-44 150.8 0.0 4.5e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Pkinase PF00069.25 KFX87136.1 - 8.1e-66 222.1 0.5 1e-65 221.8 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87136.1 - 1.6e-20 73.5 0.0 2.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX87136.1 - 3.1e-07 30.6 0.0 5.2e-05 23.3 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX87136.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX87136.1 - 0.0029 16.4 0.0 0.0059 15.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFX87136.1 - 0.016 14.6 0.3 0.044 13.1 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFX87136.1 - 0.073 12.6 0.1 0.073 12.6 0.1 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase CDP-OH_P_transf PF01066.21 KFX87137.1 - 1.5e-15 57.7 0.0 1.5e-15 57.7 0.0 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ten_N PF06484.12 KFX87138.1 - 0.062 13.2 0.1 0.062 13.2 0.1 1.4 2 0 0 2 2 2 0 Teneurin Intracellular Region peroxidase PF00141.23 KFX87140.1 - 1.6e-47 162.1 0.0 2.6e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.7 KFX87141.1 - 0.02 14.7 1.2 0.031 14.2 0.1 1.9 2 0 0 2 2 2 0 F-box-like GrpB PF04229.14 KFX87142.1 - 3.6e-44 150.8 0.0 4.1e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Epimerase PF01370.21 KFX87143.1 - 2.3e-15 56.7 0.0 3.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX87143.1 - 3.5e-12 46.0 0.0 6.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFX87143.1 - 1.5e-10 40.6 0.0 2.6e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX87143.1 - 8.6e-09 35.2 0.1 3.8e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX87143.1 - 3.7e-07 30.2 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX87143.1 - 4.5e-05 23.4 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFX87143.1 - 0.0015 19.1 0.0 0.0074 16.8 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KFX87143.1 - 0.0017 17.9 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KFX87143.1 - 0.0018 17.8 0.0 0.0051 16.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KFX87143.1 - 0.0032 16.6 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX87143.1 - 0.022 13.9 0.0 0.044 12.9 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain HSF_DNA-bind PF00447.17 KFX87144.1 - 3e-30 104.7 0.5 4.5e-30 104.1 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KFX87144.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Ets-domain LXG PF04740.12 KFX87144.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily F-box-like PF12937.7 KFX87146.1 - 0.0022 17.8 0.1 0.0047 16.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX87146.1 - 0.0081 16.0 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain ArabFuran-catal PF09206.11 KFX87147.1 - 6.6e-148 492.2 13.3 9e-148 491.7 13.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KFX87147.1 - 1.2e-56 190.6 3.5 1.8e-56 190.0 3.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain MFS_1 PF07690.16 KFX87148.1 - 1.9e-17 63.2 27.2 2.6e-17 62.8 25.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase_phd PF10503.9 KFX87148.1 - 6.2e-17 61.8 0.8 1.2e-16 60.8 0.8 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase GGACT PF06094.12 KFX87148.1 - 3e-13 50.4 0.1 2.5e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like Peptidase_S9 PF00326.21 KFX87148.1 - 9.7e-11 41.5 1.6 2.1e-10 40.5 0.8 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Sugar_tr PF00083.24 KFX87148.1 - 2.8e-05 23.2 2.6 2.8e-05 23.2 2.6 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter COesterase PF00135.28 KFX87148.1 - 0.0014 17.6 0.2 0.0025 16.8 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family CBM_1 PF00734.18 KFX87148.1 - 0.0016 18.4 9.4 0.0016 18.4 9.4 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Egh16-like PF11327.8 KFX87149.1 - 4.8e-58 196.6 11.6 4.8e-58 196.6 11.6 1.9 2 0 0 2 2 2 1 Egh16-like virulence factor Tic110 PF16940.5 KFX87149.1 - 0.17 10.3 4.7 0.22 10.0 4.7 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter ABC_membrane PF00664.23 KFX87150.1 - 3.4e-85 286.0 28.2 6.7e-43 147.3 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX87150.1 - 1e-61 207.4 0.0 9.9e-32 110.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX87150.1 - 5.2e-12 45.7 2.3 6.2e-05 22.5 1.8 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX87150.1 - 9.8e-07 29.1 0.0 0.47 10.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 KFX87150.1 - 1.1e-06 28.2 0.4 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX87150.1 - 6.4e-06 26.7 1.8 0.057 13.8 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KFX87150.1 - 4.5e-05 23.6 1.9 0.002 18.3 0.1 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KFX87150.1 - 6.1e-05 23.0 0.1 0.068 13.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KFX87150.1 - 0.00018 22.0 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFX87150.1 - 0.00022 20.6 0.0 0.094 12.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KFX87150.1 - 0.0003 21.3 0.0 0.48 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFX87150.1 - 0.00041 20.5 0.0 0.7 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFX87150.1 - 0.0006 19.4 0.1 0.23 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFX87150.1 - 0.00072 19.3 0.2 0.23 11.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KFX87150.1 - 0.0019 18.1 1.4 0.32 10.8 0.0 3.0 4 0 0 4 4 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFX87150.1 - 0.0023 18.3 0.1 23 5.4 0.1 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KFX87150.1 - 0.0025 17.7 0.1 0.74 9.7 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_ATPase PF09818.9 KFX87150.1 - 0.0048 15.7 1.8 0.69 8.6 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 KFX87150.1 - 0.0085 16.3 0.9 11 6.4 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KFX87150.1 - 0.01 15.9 2.1 2 8.5 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KFX87150.1 - 0.013 15.3 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX87150.1 - 0.026 13.7 0.2 7.2 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 KFX87150.1 - 0.027 13.5 0.0 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_15 PF13175.6 KFX87150.1 - 0.048 13.4 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KFX87150.1 - 0.055 13.9 0.0 11 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX87150.1 - 0.06 12.9 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFX87150.1 - 0.074 13.1 0.1 7.4 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pyr_redox_2 PF07992.14 KFX87151.1 - 1.7e-27 96.4 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX87151.1 - 3.3e-09 37.2 0.4 1.2e-07 32.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX87151.1 - 0.0023 17.2 1.5 4.2 6.5 0.6 3.8 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX87151.1 - 0.086 12.0 0.2 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Alpha-amylase PF00128.24 KFX87152.1 - 7.6e-54 183.5 0.0 1.4e-53 182.7 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.16 KFX87152.1 - 3e-18 65.9 46.7 3e-18 65.9 46.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1966 PF09260.11 KFX87152.1 - 2.7e-13 50.0 1.1 2.3e-12 47.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) TRI12 PF06609.13 KFX87152.1 - 3.2e-09 35.8 23.8 6.2e-09 34.8 23.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1428 PF07237.11 KFX87152.1 - 0.16 12.3 0.0 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) GHL10 PF02638.15 KFX87152.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 NmrA PF05368.13 KFX87153.1 - 0.00022 20.9 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Pkinase PF00069.25 KFX87155.1 - 7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87155.1 - 4.6e-05 22.8 0.0 0.00011 21.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.18 KFX87156.1 - 5.2 7.3 12.2 10 6.3 12.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mtc PF03820.17 KFX87157.1 - 6.3e-37 127.3 0.0 7e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier AMPK1_CBM PF16561.5 KFX87158.1 - 0.023 14.9 0.1 0.097 12.9 0.0 1.9 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase FA_hydroxylase PF04116.13 KFX87159.1 - 4.6e-23 82.0 11.1 4.6e-23 82.0 11.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3606 PF12244.8 KFX87159.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Transport_MerF PF11431.8 KFX87159.1 - 0.25 11.3 2.5 2.3 8.1 0.6 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF TCTP PF00838.17 KFX87160.1 - 1.3e-70 237.0 4.3 1.5e-70 236.9 4.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein S4 PF01479.25 KFX87160.1 - 0.019 14.7 0.2 0.23 11.2 0.2 2.3 1 1 1 2 2 2 0 S4 domain Lactamase_B_4 PF13691.6 KFX87161.1 - 1.2e-27 95.3 0.1 6e-27 93.1 0.1 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KFX87161.1 - 2.5e-13 50.0 0.0 5.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFX87161.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily MIP PF00230.20 KFX87165.1 - 7.1e-50 169.8 3.9 8.8e-50 169.5 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2644 PF10841.8 KFX87165.1 - 1.2 9.4 4.6 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) p450 PF00067.22 KFX87166.1 - 7.6e-15 54.6 0.1 8.2e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Wzy_C PF04932.15 KFX87167.1 - 0.039 13.6 0.2 0.039 13.6 0.2 2.9 2 1 1 3 3 3 0 O-Antigen ligase NUP PF06516.11 KFX87168.1 - 2.2e-127 424.6 0.0 2.7e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ank_2 PF12796.7 KFX87169.1 - 1.3e-23 83.3 0.0 8.2e-11 42.3 0.0 3.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX87169.1 - 9.2e-19 65.6 0.2 0.0017 18.7 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KFX87169.1 - 8.8e-18 63.9 1.9 5.4e-06 26.6 0.1 6.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 KFX87169.1 - 5e-15 55.6 0.1 8.3e-07 29.4 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX87169.1 - 9.2e-14 51.3 0.2 0.00024 21.4 0.0 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 KFX87169.1 - 9.1e-06 25.7 0.2 3.1e-05 24.0 0.2 1.9 1 0 0 1 1 1 1 NACHT domain VCBS PF13517.6 KFX87170.1 - 3.1e-32 111.0 49.1 1.6e-12 47.9 0.7 7.5 4 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX87170.1 - 8.1e-23 81.7 4.5 2.6e-13 50.8 0.3 3.0 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX87170.1 - 3.6e-12 46.7 0.3 8.8e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KFX87170.1 - 2.8e-11 43.1 2.3 0.13 11.6 0.0 6.7 5 2 2 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Aspzincin_M35 PF14521.6 KFX87170.1 - 7.4e-11 42.8 0.3 2.6e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase FG-GAP PF01839.23 KFX87170.1 - 4.9e-09 36.2 20.7 0.038 14.1 0.3 6.1 5 0 0 5 5 5 4 FG-GAP repeat Lipase_GDSL_3 PF14606.6 KFX87170.1 - 0.015 15.4 0.2 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Dockerin_1 PF00404.18 KFX87170.1 - 0.37 11.0 14.3 1.4 9.2 0.1 5.6 6 0 0 6 6 6 0 Dockerin type I domain Macoilin PF09726.9 KFX87172.1 - 0.31 9.6 4.9 0.32 9.5 4.9 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KFX87172.1 - 2.8 5.0 6.2 3 4.8 6.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 KFX87172.1 - 3 6.4 4.2 2.8 6.5 4.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KFX87172.1 - 3.5 6.3 10.2 3.7 6.2 10.2 1.1 1 0 0 1 1 1 0 Presenilin Mannosyl_trans2 PF04188.13 KFX87178.1 - 5.7e-55 187.4 3.3 7.6e-55 187.0 3.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) CHCH PF06747.13 KFX87178.1 - 0.22 11.7 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 CHCH domain Fic PF02661.18 KFX87181.1 - 3.4e-20 72.7 0.0 1.5e-19 70.6 0.0 2.1 3 0 0 3 3 3 1 Fic/DOC family PH PF00169.29 KFX87182.1 - 2.4e-05 24.8 0.1 5.7e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 KFX87182.1 - 0.14 10.1 0.2 0.23 9.4 0.2 1.2 1 0 0 1 1 1 0 Prominin tRNA-synt_2b PF00587.25 KFX87183.1 - 3e-32 112.0 0.0 5.6e-29 101.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFX87183.1 - 1.3e-18 66.9 0.1 3.2e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KFX87183.1 - 5.7e-13 48.7 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KFX87183.1 - 2e-12 47.0 0.0 4.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Gar1 PF04410.14 KFX87184.1 - 3.5e-38 130.8 0.0 4.5e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF2013 PF09431.10 KFX87185.1 - 2.5e-50 170.2 4.4 2.5e-50 170.2 4.4 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2013) RHH_4 PF13467.6 KFX87185.1 - 0.088 12.7 0.1 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain DnaJ PF00226.31 KFX87186.1 - 2.3e-19 69.3 5.3 3.1e-19 68.9 1.2 3.1 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 KFX87186.1 - 1.5e-14 53.1 0.0 0.0025 17.5 0.0 5.4 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX87186.1 - 8.3e-14 50.5 0.2 0.098 12.8 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX87186.1 - 5.1e-12 45.0 0.5 0.02 15.0 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX87186.1 - 4e-09 36.8 1.3 0.0081 16.7 0.0 4.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFX87186.1 - 8.6e-09 35.4 0.1 0.0088 16.2 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX87186.1 - 3.6e-07 30.4 0.0 0.077 13.7 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX87186.1 - 6.8e-07 28.9 0.1 0.0061 16.5 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX87186.1 - 1.2e-06 28.4 0.1 0.0041 17.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX87186.1 - 2.3e-05 24.8 0.1 3.6 8.6 0.0 5.9 2 2 7 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX87186.1 - 0.00035 20.8 4.5 2.7 8.4 0.0 5.3 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX87186.1 - 0.00041 20.0 0.3 0.0052 16.4 0.0 2.9 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KFX87186.1 - 0.00082 19.6 7.1 20 5.5 2.2 4.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 KFX87186.1 - 0.00095 18.0 0.0 0.007 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_16 PF13432.6 KFX87186.1 - 0.011 16.3 0.0 1.1 10.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX87186.1 - 0.026 14.4 1.6 9.4 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Transcrip_act PF04949.13 KFX87186.1 - 0.031 14.2 0.9 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 Transcriptional activator MerR-DNA-bind PF09278.11 KFX87187.1 - 1.8 9.2 0.0 1.8 9.2 0.0 3.8 4 0 0 4 4 4 0 MerR, DNA binding Vac14_Fig4_bd PF11916.8 KFX87188.1 - 4.2e-81 270.9 8.1 4.2e-81 270.9 8.1 2.0 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFX87188.1 - 1.3e-45 154.0 0.0 2e-42 143.7 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFX87188.1 - 9.4e-11 42.0 2.9 0.0047 17.4 0.1 5.4 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 KFX87188.1 - 4.9e-08 32.6 1.0 0.0019 18.3 0.0 5.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KFX87188.1 - 7.7e-06 26.0 0.2 0.005 16.9 0.4 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX87188.1 - 0.00012 22.4 2.4 0.37 11.2 0.0 5.0 5 1 0 5 5 5 1 HEAT repeats CLASP_N PF12348.8 KFX87188.1 - 0.01 15.4 0.1 2.1 7.8 0.0 3.9 3 1 1 4 4 4 0 CLASP N terminal Arm PF00514.23 KFX87188.1 - 0.019 15.0 0.0 16 5.7 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.24 KFX87189.1 - 9e-25 87.9 26.1 1.3e-24 87.4 26.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFX87189.1 - 3.1e-08 33.7 0.0 7.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KFX87191.1 - 7.8e-69 232.1 10.1 1.5e-68 231.2 8.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFX87191.1 - 1.1e-40 138.2 0.2 3.6e-40 136.6 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFX87191.1 - 3.2e-21 75.7 12.8 9.7e-19 67.7 1.0 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX87191.1 - 7.5e-10 38.9 5.0 2.6e-06 27.6 0.9 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFX87191.1 - 9.5e-10 38.4 0.7 9.5e-10 38.4 0.7 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KFX87191.1 - 1e-09 38.0 8.6 7.6e-09 35.1 2.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX87191.1 - 1.2e-07 31.2 11.3 1.7e-07 30.7 3.8 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KFX87191.1 - 7.5e-07 28.7 5.5 0.0044 16.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KFX87191.1 - 1.3e-06 27.9 5.9 0.0006 19.2 0.5 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX87191.1 - 2.8e-06 26.8 7.1 0.0037 16.6 0.7 2.8 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFX87191.1 - 3.1e-06 26.6 3.6 4.5e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KFX87191.1 - 4.2e-05 22.4 17.0 7.5e-05 21.6 2.3 4.0 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 KFX87191.1 - 0.00012 21.8 18.3 0.00047 19.8 0.6 4.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFX87191.1 - 0.00026 20.3 0.9 0.8 8.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KFX87191.1 - 0.0025 17.0 2.3 0.013 14.5 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KFX87191.1 - 0.014 15.8 3.6 2.2 8.7 0.5 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KFX87191.1 - 0.055 12.8 1.1 1.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.19 KFX87191.1 - 0.22 9.9 0.7 0.35 9.2 0.7 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KFX87191.1 - 3.7 6.3 9.7 0.029 13.2 1.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KFX87191.1 - 6.6 6.6 8.7 2.5 8.0 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX87191.1 - 8.5 5.9 6.9 11 5.5 0.4 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SRP14 PF02290.15 KFX87192.1 - 3.7e-31 107.4 0.1 5.8e-31 106.7 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein MA3 PF02847.17 KFX87193.1 - 6.4e-21 74.4 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KFX87193.1 - 1.1e-20 74.3 0.3 1.9e-20 73.4 0.3 1.4 1 0 0 1 1 1 1 MIF4G domain RAMP4 PF06624.12 KFX87193.1 - 0.3 11.2 2.4 5.9 7.0 1.5 2.5 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 RRM_1 PF00076.22 KFX87194.1 - 2.3e-53 177.9 0.0 1.4e-17 63.2 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX87194.1 - 2.1e-05 24.1 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFX87194.1 - 2.5e-05 24.2 0.0 0.97 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFX87194.1 - 2.7e-05 24.2 0.1 3.8 7.7 0.0 4.2 4 1 0 4 4 4 3 Limkain b1 ATP-grasp_2 PF08442.10 KFX87194.1 - 0.00047 19.8 0.0 0.037 13.6 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain RRM_occluded PF16842.5 KFX87194.1 - 0.12 12.3 0.0 8.2 6.4 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF3343 PF11823.8 KFX87194.1 - 0.19 11.2 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Arv1 PF04161.13 KFX87196.1 - 1.4e-78 263.9 0.0 1.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 KFX87197.1 - 4e-24 84.9 1.9 4.5e-24 84.7 1.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.11 KFX87197.1 - 0.075 12.5 0.5 0.092 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Pox_A14 PF05767.12 KFX87197.1 - 0.12 12.5 1.2 0.15 12.2 1.2 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MutL_C PF08676.11 KFX87198.1 - 3e-24 85.5 0.0 6.6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFX87198.1 - 7.7e-19 67.5 0.0 2.3e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFX87198.1 - 4.6e-13 49.2 1.2 1.2e-11 44.6 0.1 3.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFX87198.1 - 4.6e-07 30.3 0.4 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PEGSRP PF07623.11 KFX87199.1 - 0.12 12.2 0.7 0.41 10.5 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Pyr_redox_2 PF07992.14 KFX87200.1 - 4.9e-08 32.6 0.0 9.9e-06 25.0 0.0 3.0 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.21 KFX87201.1 - 4.7e-44 150.5 3.1 7.9e-44 149.7 3.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFX87201.1 - 4.3e-33 113.2 0.4 1.1e-32 111.9 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM-assoc_1 PF16495.5 KFX87202.1 - 1.2e-31 108.4 8.5 2.4e-31 107.5 8.5 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 KFX87202.1 - 2.9e-31 107.6 0.2 6.7e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KFX87202.1 - 7.5e-10 38.9 0.1 1.5e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX87202.1 - 2.9e-05 24.2 0.1 7.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mei5 PF10376.9 KFX87202.1 - 0.052 13.4 0.6 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein PWI PF01480.17 KFX87203.1 - 3.5e-09 36.8 0.1 7e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFX87203.1 - 0.00024 20.9 5.8 0.00047 20.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFX87203.1 - 0.00065 19.5 0.2 0.00065 19.5 0.2 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX87203.1 - 0.0014 18.6 0.1 0.0093 15.9 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KFX87203.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf_CCCH_4 PF18345.1 KFX87203.1 - 0.04 14.0 4.4 0.07 13.2 4.4 1.4 1 0 0 1 1 1 0 Zinc finger domain PHM7_cyt PF14703.6 KFX87203.1 - 0.11 12.7 1.4 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KFX87203.1 - 0.95 9.5 6.9 0.44 10.6 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif zf-CCCH_4 PF18044.1 KFX87203.1 - 1.2 9.0 5.9 2.3 8.1 5.9 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger CLZ PF16526.5 KFX87203.1 - 5.5 7.4 12.2 1.9 8.9 8.9 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2937 PF11157.8 KFX87203.1 - 6.8 6.4 6.1 1.2 8.8 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Myb_DNA-binding PF00249.31 KFX87204.1 - 0.044 14.0 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain GTP_EFTU PF00009.27 KFX87205.1 - 1.1e-65 220.8 0.2 1.6e-65 220.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFX87205.1 - 3.8e-32 110.6 0.0 4.5e-31 107.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFX87205.1 - 5.4e-21 74.4 0.0 2.4e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX87205.1 - 1.2e-12 48.1 0.0 7.2e-12 45.5 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFX87205.1 - 1.4e-11 44.3 0.0 3.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFX87205.1 - 0.00032 20.8 0.2 0.00065 19.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ycf54 PF10674.9 KFX87206.1 - 0.056 13.7 0.2 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) Solute_trans_a PF03619.16 KFX87207.1 - 6e-100 334.1 6.0 7.2e-100 333.9 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4400 PF14348.6 KFX87208.1 - 0.015 14.8 1.9 0.021 14.3 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) WXG100 PF06013.12 KFX87208.1 - 0.039 14.2 0.1 0.098 12.9 0.1 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG VPS38 PF17649.1 KFX87208.1 - 5.6 5.7 13.3 1.8 7.3 6.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 38 PhoLip_ATPase_C PF16212.5 KFX87211.1 - 1.3e-82 277.3 18.8 1.3e-82 277.3 18.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX87211.1 - 5.8e-26 90.0 8.3 1.5e-25 88.6 8.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFX87211.1 - 1.6e-10 40.9 0.0 6.4e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX87211.1 - 1.7e-10 41.6 2.5 1.7e-06 28.5 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFX87211.1 - 3.1e-06 26.8 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX87211.1 - 0.00081 19.2 0.1 0.0094 15.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PHF5 PF03660.14 KFX87212.1 - 3.2e-35 120.5 6.2 4.6e-35 120.0 6.2 1.2 1 0 0 1 1 1 1 PHF5-like protein Pex26 PF07163.12 KFX87213.1 - 0.013 14.8 2.5 0.013 14.8 2.5 1.7 2 0 0 2 2 2 0 Pex26 protein DUF572 PF04502.13 KFX87213.1 - 4.4 6.8 9.7 1.7 8.2 6.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) CAF1 PF04857.20 KFX87214.1 - 1.1e-80 271.3 0.5 1.3e-80 271.0 0.5 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KFX87214.1 - 0.00034 20.4 0.1 0.00081 19.1 0.1 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Acetyltransf_3 PF13302.7 KFX87215.1 - 3.7e-31 108.7 0.0 5.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 KFX87215.1 - 8.6e-05 21.2 0.0 0.00016 20.3 0.0 1.4 2 0 0 2 2 2 1 Arginine N-succinyltransferase beta subunit Acetyltransf_1 PF00583.25 KFX87215.1 - 0.0037 17.5 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WD40 PF00400.32 KFX87216.1 - 0.00056 20.7 16.8 0.11 13.4 2.6 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ PF01011.21 KFX87216.1 - 0.016 15.1 1.4 27 4.9 0.3 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Methyltransf_11 PF08241.12 KFX87217.1 - 1.5e-05 25.6 0.0 3.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87217.1 - 3.2e-05 23.8 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87217.1 - 0.00065 19.6 0.0 0.00099 19.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87217.1 - 0.00066 20.3 0.0 0.0017 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX87217.1 - 0.011 16.4 0.0 0.019 15.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fe_hyd_lg_C PF02906.14 KFX87217.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TMEM247 PF15444.6 KFX87220.1 - 9.5 6.2 6.5 2.8 7.9 2.5 2.1 1 1 1 2 2 2 0 Transmembrane protein 247 GCV_T PF01571.21 KFX87221.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 KFX87222.1 - 1.7e-30 105.2 0.6 2.9e-30 104.4 0.6 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KFX87222.1 - 2.4e-17 63.2 0.1 4.4e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 KFX87223.1 - 5e-36 123.1 0.3 6.6e-36 122.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.21 KFX87224.1 - 5.8e-122 406.5 3.7 7.2e-122 406.2 3.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KFX87225.1 - 1.3e-30 105.6 1.0 1.8e-30 105.2 1.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF1308 PF07000.11 KFX87226.1 - 1e-09 38.5 0.0 9e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KFX87226.1 - 7.1e-08 32.0 0.1 0.001 18.4 0.0 2.8 2 1 0 2 2 2 2 Family of unknown function (DUF5614) Sigma70_r1_1 PF03979.14 KFX87226.1 - 0.055 13.5 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Lung_7-TM_R PF06814.13 KFX87228.1 - 2.3e-72 243.8 15.5 2.8e-72 243.5 15.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CTU2 PF10288.9 KFX87229.1 - 2.3e-14 53.6 2.8 9.3e-14 51.6 0.2 2.8 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KFX87229.1 - 0.022 14.5 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 PP-loop family Vfa1 PF08432.10 KFX87231.1 - 3e-56 190.6 19.0 3.4e-56 190.5 19.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 KFX87231.1 - 1.7e-05 23.8 5.0 1.9e-05 23.6 5.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family MTBP_N PF14918.6 KFX87231.1 - 0.0046 16.5 1.7 0.0055 16.2 1.7 1.2 1 0 0 1 1 1 1 MDM2-binding CDC45 PF02724.14 KFX87231.1 - 0.0072 14.7 11.2 0.0071 14.7 11.2 1.0 1 0 0 1 1 1 1 CDC45-like protein Afi1 PF07792.12 KFX87231.1 - 0.018 15.5 6.6 0.024 15.1 6.6 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SRP-alpha_N PF04086.13 KFX87231.1 - 0.019 14.9 18.8 0.025 14.5 18.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Atrophin-1 PF03154.15 KFX87231.1 - 0.072 11.4 16.8 0.089 11.1 16.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family RR_TM4-6 PF06459.12 KFX87231.1 - 0.077 12.8 15.9 0.098 12.5 15.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KFX87231.1 - 0.11 11.2 5.7 0.11 11.3 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 KFX87231.1 - 0.15 10.4 2.3 0.15 10.4 2.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.12 KFX87231.1 - 0.17 10.8 3.7 0.18 10.8 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 KFX87231.1 - 0.2 10.4 9.8 0.21 10.3 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 KFX87231.1 - 0.29 11.3 3.3 0.33 11.1 3.3 1.1 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 KFX87231.1 - 0.33 9.9 7.5 0.36 9.8 7.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 KFX87231.1 - 0.38 9.2 21.6 0.45 9.0 21.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Connexin PF00029.19 KFX87231.1 - 0.44 10.3 8.3 0.55 10.0 8.3 1.3 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 KFX87231.1 - 0.62 10.2 9.3 0.93 9.7 9.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PPL5 PF18168.1 KFX87231.1 - 0.7 9.1 10.7 0.85 8.9 10.7 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF3438 PF11920.8 KFX87231.1 - 1.1 8.5 6.4 1.2 8.3 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Neur_chan_memb PF02932.16 KFX87231.1 - 1.3 9.0 3.8 1.3 9.0 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rrn6 PF10214.9 KFX87231.1 - 1.3 7.4 9.2 1.6 7.1 9.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SpoIIP PF07454.11 KFX87231.1 - 1.4 8.3 12.2 1.7 8.0 12.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Astro_capsid_p PF12226.8 KFX87231.1 - 1.6 7.8 7.9 2 7.5 7.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_S49_N PF08496.10 KFX87231.1 - 1.8 8.6 16.6 3.1 7.8 16.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TP53IP5 PF15331.6 KFX87231.1 - 2 8.5 13.6 2.6 8.1 13.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 TRAP_alpha PF03896.16 KFX87231.1 - 2.1 7.5 8.7 2.7 7.1 8.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF908 PF06012.12 KFX87231.1 - 2.1 7.7 4.9 2.5 7.4 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RNA_pol_Rpc4 PF05132.14 KFX87231.1 - 2.7 8.4 15.1 0.068 13.6 8.7 1.7 2 0 0 2 2 1 0 RNA polymerase III RPC4 ATP11 PF06644.11 KFX87231.1 - 3 7.6 15.5 3.5 7.3 15.5 1.1 1 0 0 1 1 1 0 ATP11 protein Zip PF02535.22 KFX87231.1 - 3 7.0 6.7 3.6 6.7 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GNAT_acetyltr_2 PF13718.6 KFX87231.1 - 4.5 6.6 6.0 5.9 6.2 6.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Presenilin PF01080.17 KFX87231.1 - 8 5.1 13.8 9.6 4.9 13.8 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFX87231.1 - 8.1 5.1 7.6 9.5 4.9 7.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Rtt106 PF08512.12 KFX87232.1 - 1.9e-30 105.1 0.0 4.1e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KFX87232.1 - 0.028 14.4 0.1 0.27 11.2 0.2 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain MDD_C PF18376.1 KFX87233.1 - 1.1e-66 224.1 0.0 1.3e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain Trp_syntA PF00290.20 KFX87236.1 - 4.6e-94 314.1 0.4 8e-94 313.3 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 KFX87236.1 - 1e-48 166.3 2.2 2e-48 165.3 2.2 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 KFX87237.1 - 2.2e-15 57.3 0.0 3.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX87237.1 - 0.0012 19.1 0.2 0.025 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX87237.1 - 0.003 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFX87237.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KFX87237.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KFX87238.1 - 2.3e-60 204.2 0.0 2.8e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87238.1 - 4.1e-30 104.9 0.0 5.2e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX87238.1 - 0.00042 19.7 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFX87238.1 - 0.0016 17.8 0.2 0.0032 16.9 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX87238.1 - 0.0084 16.0 0.5 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFX87238.1 - 0.072 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFX87238.1 - 0.097 11.6 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain A1_Propeptide PF07966.12 KFX87238.1 - 0.11 12.4 0.3 0.22 11.4 0.3 1.5 1 0 0 1 1 1 0 A1 Propeptide KCNQC3-Ank-G_bd PF11956.8 KFX87238.1 - 0.16 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 DUF1640 PF07798.11 KFX87239.1 - 2.2e-39 135.3 9.8 2.2e-39 135.3 9.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) MSC PF09402.10 KFX87239.1 - 0.38 10.2 8.1 0.52 9.7 8.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain CAS_CSE1 PF03378.15 KFX87240.1 - 3.6e-164 546.5 0.0 2e-163 544.0 0.0 2.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KFX87240.1 - 9.2e-156 518.3 0.6 1.4e-155 517.7 0.6 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KFX87240.1 - 1.8e-12 47.0 0.0 6.2e-12 45.3 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFX87240.1 - 0.035 14.2 8.1 0.66 10.0 0.0 5.6 6 1 0 6 6 6 0 Exportin 1-like protein DUF3384 PF11864.8 KFX87241.1 - 2.8e-127 425.6 0.0 5.3e-127 424.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KFX87241.1 - 7.3e-53 178.9 0.0 1.2e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KFX87241.1 - 7.9e-41 140.3 0.8 7.9e-37 127.2 0.0 3.0 3 0 0 3 3 3 2 Tuberin DER1 PF04511.15 KFX87242.1 - 5.8e-25 88.3 4.7 6.8e-25 88.1 4.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF1770 PF08589.10 KFX87243.1 - 2e-34 118.5 1.7 2e-34 118.5 0.9 1.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) ABC_tran PF00005.27 KFX87244.1 - 1.1e-16 61.6 0.0 3.3e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFX87244.1 - 9.7e-11 42.0 2.4 0.00015 21.7 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX87244.1 - 0.00018 21.0 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX87244.1 - 0.00047 19.8 0.4 0.0011 18.7 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX87244.1 - 0.0026 18.3 0.0 0.0053 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFX87244.1 - 0.0029 17.4 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF3584 PF12128.8 KFX87244.1 - 0.0083 13.7 0.3 0.011 13.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_16 PF13191.6 KFX87244.1 - 0.0099 16.3 0.2 0.017 15.5 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KFX87244.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KFX87244.1 - 0.032 13.8 0.1 0.046 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 KFX87244.1 - 0.067 12.0 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 KFX87244.1 - 0.071 13.3 0.3 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFX87244.1 - 0.083 13.2 0.5 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX87244.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KFX87244.1 - 0.16 12.0 0.8 0.83 9.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KFX87244.1 - 0.2 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 KFX87244.1 - 0.21 10.2 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KFX87245.1 - 4e-38 128.7 19.4 1.2e-07 32.2 0.0 12.6 13 0 0 13 13 13 9 WD domain, G-beta repeat WHIM1 PF15612.6 KFX87246.1 - 5.3e-06 25.8 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 MSP1_C PF07462.11 KFX87246.1 - 2.1 6.9 5.1 3.5 6.2 5.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L2_C PF03947.18 KFX87247.1 - 4.8e-41 139.9 4.8 8.3e-41 139.1 4.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFX87247.1 - 1.3e-14 53.9 0.1 2.9e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KFX87248.1 - 2.6e-67 227.3 0.1 2.9e-67 227.1 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFX87248.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KFX87249.1 - 1e-54 186.0 0.0 2e-54 185.0 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFX87249.1 - 2.8e-21 76.6 1.5 8e-21 75.1 1.5 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 Sec2p PF06428.11 KFX87249.1 - 0.14 12.2 0.3 0.31 11.0 0.3 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p zf-C2H2_jaz PF12171.8 KFX87250.1 - 0.048 14.0 1.7 0.29 11.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFX87250.1 - 0.4 11.2 14.5 0.6 10.7 1.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TB2_DP1_HVA22 PF03134.19 KFX87251.1 - 9.3e-29 99.2 6.2 9.3e-29 99.2 6.2 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 KFX87251.1 - 0.082 12.3 2.0 0.1 12.0 2.0 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.15 KFX87252.1 - 1.3e-28 99.4 0.2 4.7e-28 97.6 0.1 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Beta-lactamase PF00144.24 KFX87254.1 - 1.6e-46 159.1 0.3 2.8e-46 158.3 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KFX87254.1 - 5.1e-18 65.5 0.0 9.2e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Pec_lyase_C PF00544.19 KFX87255.1 - 7.3e-43 146.6 0.4 1e-42 146.1 0.4 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX87255.1 - 0.0017 18.2 1.9 0.037 13.9 1.9 2.4 1 1 0 1 1 1 1 Right handed beta helix region NCBP3 PF10309.9 KFX87256.1 - 3.4e-22 78.1 0.0 5.6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 TPR_MLP1_2 PF07926.12 KFX87256.1 - 3.4 7.7 20.4 0.052 13.6 12.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Aspzincin_M35 PF14521.6 KFX87257.1 - 2.2e-06 28.3 0.1 2.9e-05 24.7 0.1 2.4 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ank_4 PF13637.6 KFX87259.1 - 1.2e-09 38.5 0.1 0.15 12.7 0.0 5.1 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX87259.1 - 2.6e-07 30.4 0.2 1.1 10.0 0.0 5.3 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 KFX87259.1 - 0.00074 19.9 0.0 8.5 7.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KFX87259.1 - 0.0014 19.2 0.0 0.84 10.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX87260.1 - 2.6e-17 62.9 0.2 0.0069 16.9 0.0 5.7 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX87260.1 - 1.2e-14 54.6 0.1 2.2e-05 25.0 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX87260.1 - 2.6e-08 33.5 7.7 2.8 8.8 0.0 7.0 7 1 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KFX87260.1 - 5.5e-07 29.8 4.9 0.027 14.8 0.0 5.4 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX87260.1 - 3.5e-05 24.1 0.4 74 4.0 0.1 5.8 6 0 0 6 6 6 0 Ankyrin repeat DUF1843 PF08898.10 KFX87260.1 - 0.003 18.0 0.0 2.4 8.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1843) Epimerase PF01370.21 KFX87261.1 - 8.4e-12 45.1 0.2 3.3e-11 43.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX87261.1 - 1.9e-08 33.7 0.0 3.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX87261.1 - 4.5e-07 29.6 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFX87261.1 - 1.5e-06 28.0 0.4 3.2e-06 26.9 0.3 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KFX87261.1 - 3.4e-05 23.2 0.0 0.0007 18.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFX87261.1 - 5e-05 23.3 0.4 8.7e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX87261.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KFX87261.1 - 0.058 13.3 2.4 0.25 11.2 2.4 2.0 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KFX87261.1 - 0.071 12.6 0.3 0.52 9.7 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Ank_2 PF12796.7 KFX87262.1 - 4e-32 110.6 0.0 3.5e-09 37.1 0.0 5.7 3 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX87262.1 - 1.2e-17 62.1 9.1 0.85 10.4 0.1 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 KFX87262.1 - 7.5e-16 58.3 3.2 0.0092 16.6 0.8 6.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KFX87262.1 - 1.4e-14 53.8 1.3 0.11 13.0 0.2 7.3 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFX87262.1 - 2.8e-10 40.2 5.7 0.00023 21.4 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KFX87262.1 - 0.0021 17.9 0.5 0.0095 15.8 0.3 2.1 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 KFX87263.1 - 2.3e-37 128.7 25.2 2.8e-37 128.5 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1449 PF07290.11 KFX87263.1 - 0.035 13.7 0.1 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) UNC-93 PF05978.16 KFX87263.1 - 2 8.1 14.1 0.012 15.4 5.1 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.18 KFX87264.1 - 1.1e-21 77.1 0.3 2e-20 72.9 0.3 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87264.1 - 6.5e-06 26.2 6.2 1.1e-05 25.4 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.12 KFX87265.1 - 9.1e-62 207.2 0.0 1.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.14 KFX87266.1 - 2.7e-217 722.2 0.2 3.8e-217 721.8 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFX87266.1 - 1.1e-102 343.3 0.5 2.2e-102 342.3 0.2 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFX87266.1 - 1e-56 191.5 1.3 2e-55 187.3 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region IGPD PF00475.18 KFX87266.1 - 0.082 13.2 0.2 5.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase CoA_binding_2 PF13380.6 KFX87267.1 - 8.4e-29 100.4 0.0 1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HET PF06985.11 KFX87268.1 - 1.4e-12 48.2 3.8 1.7e-09 38.2 0.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KFX87269.1 - 6.1e-05 23.1 8.8 0.00019 21.5 8.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.20 KFX87270.1 - 2.6e-33 115.4 0.0 3.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KFX87270.1 - 0.00012 22.3 0.0 0.00049 20.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Rib PF08428.10 KFX87270.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Rib/alpha-like repeat Otopetrin PF03189.13 KFX87271.1 - 0.26 10.1 7.3 0.38 9.5 7.3 1.2 1 0 0 1 1 1 0 Otopetrin COesterase PF00135.28 KFX87272.1 - 1.1e-81 275.3 0.0 2e-81 274.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX87272.1 - 5e-06 26.5 0.3 3.4e-05 23.8 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFX87272.1 - 0.012 14.5 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme 5-FTHF_cyc-lig PF01812.20 KFX87273.1 - 4.9e-31 108.0 0.0 5.8e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CdiI_N PF18228.1 KFX87273.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 CdiI N-terminal domain ETC_C1_NDUFA5 PF04716.14 KFX87274.1 - 2e-28 98.0 0.6 5e-26 90.3 0.0 2.4 2 0 0 2 2 2 2 ETC complex I subunit conserved region Sfi1 PF08457.10 KFX87274.1 - 0.031 12.8 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein Thioredoxin PF00085.20 KFX87275.1 - 8.1e-40 135.0 0.2 7.4e-24 83.7 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFX87275.1 - 2.9e-11 43.6 0.0 1.3e-06 28.5 0.0 4.1 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFX87275.1 - 3.3e-05 24.1 0.1 0.65 10.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KFX87275.1 - 0.00024 21.1 0.0 0.18 11.9 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KFX87275.1 - 0.0016 18.8 5.2 1.8 9.0 0.2 4.7 3 2 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 KFX87275.1 - 0.0074 16.1 3.2 3.2 7.5 0.0 3.2 2 1 1 3 3 3 2 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFX87275.1 - 0.031 13.6 0.0 18 4.6 0.0 3.2 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DEC-1_N PF04625.13 KFX87275.1 - 0.5 9.3 4.0 0.89 8.5 4.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Tyr-DNA_phospho PF06087.12 KFX87276.1 - 1.6e-148 495.2 0.0 1.8e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KFX87276.1 - 0.098 12.5 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain PLDc PF00614.22 KFX87276.1 - 0.13 12.5 0.1 8.7 6.7 0.4 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.19 KFX87277.1 - 2.5e-21 75.7 1.1 2.8e-21 75.5 1.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Piwi PF02171.17 KFX87278.1 - 1.9e-64 217.8 0.0 2.8e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 KFX87278.1 - 4.8e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KFX87278.1 - 6.1e-10 39.3 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KFX87278.1 - 1.1e-09 37.8 0.0 3.2e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFX87278.1 - 5.4e-06 26.3 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 KFX87278.1 - 2.9e-05 24.7 0.0 7.4e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of argonaute Arm-DNA-bind_2 PF12167.8 KFX87278.1 - 0.025 14.5 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain Amidohydro_1 PF01979.20 KFX87281.1 - 2.4e-77 260.6 0.6 2.4e-77 260.6 0.6 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KFX87281.1 - 7e-55 184.5 2.1 1.8e-54 183.2 2.1 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KFX87281.1 - 1.2e-40 137.5 1.2 1.7e-40 137.0 0.3 1.7 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KFX87281.1 - 5.9e-39 132.4 0.1 1.2e-38 131.4 0.1 1.5 1 0 0 1 1 1 1 Urease, gamma subunit MFS_1 PF07690.16 KFX87281.1 - 1e-23 83.9 28.8 1e-23 83.9 28.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_3 PF07969.11 KFX87281.1 - 1.8e-09 37.6 1.1 1.6e-06 27.9 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family MFS_2 PF13347.6 KFX87281.1 - 0.0012 17.5 0.9 0.0012 17.5 0.9 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 KFX87281.1 - 0.19 10.5 8.5 0.04 12.8 3.3 2.0 2 0 0 2 2 2 0 Sugar (and other) transporter zf-RING_2 PF13639.6 KFX87282.1 - 8e-13 48.5 6.6 1.5e-12 47.6 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX87282.1 - 5e-08 32.5 1.9 5e-08 32.5 1.9 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFX87282.1 - 5.8e-08 32.4 6.4 5.8e-08 32.4 6.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX87282.1 - 1.6e-06 27.9 5.4 1.6e-06 27.9 5.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX87282.1 - 5.1e-06 26.4 7.8 1.5e-05 24.9 7.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFX87282.1 - 5.8e-06 26.2 4.1 1.1e-05 25.3 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFX87282.1 - 4.5e-05 23.6 8.5 0.00021 21.5 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFX87282.1 - 0.00012 21.8 3.7 0.00026 20.8 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX87282.1 - 0.0017 18.4 4.0 0.0044 17.0 3.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFX87282.1 - 0.007 16.5 5.3 0.019 15.1 5.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFX87282.1 - 0.04 13.5 1.9 0.098 12.3 1.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KFX87282.1 - 0.048 14.0 1.5 0.048 14.0 1.5 2.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_4 PF14447.6 KFX87282.1 - 0.057 13.3 13.3 0.61 10.0 11.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFX87282.1 - 0.072 12.9 3.4 0.14 12.0 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KFX87282.1 - 0.19 11.6 6.5 0.52 10.2 5.3 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LapA_dom PF06305.11 KFX87282.1 - 0.29 11.0 0.8 0.71 9.7 0.8 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PHD PF00628.29 KFX87282.1 - 0.3 11.0 3.4 0.55 10.2 3.4 1.4 1 0 0 1 1 1 0 PHD-finger YdjO PF14169.6 KFX87282.1 - 0.34 10.7 1.2 25 4.7 0.1 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Ada3 PF10198.9 KFX87283.1 - 1.3e-47 161.2 0.6 1.3e-47 161.2 0.6 2.8 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 DUF1682 PF07946.14 KFX87283.1 - 0.44 9.7 4.2 0.83 8.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Maf PF02545.14 KFX87284.1 - 2.5e-36 125.0 0.1 2.8e-36 124.9 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein EF-1_beta_acid PF10587.9 KFX87284.1 - 7.3 7.1 9.3 1.1 9.8 5.3 1.8 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region NPR2 PF06218.11 KFX87285.1 - 1.3e-126 422.9 3.4 1.2e-107 360.4 2.4 2.6 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 KFX87285.1 - 0.22 10.3 0.0 0.67 8.7 0.0 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SnoaL_4 PF13577.6 KFX87287.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 KFX87288.1 - 1.1e-17 64.1 45.1 1.1e-17 64.1 45.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 KFX87289.1 - 0.018 14.0 0.0 0.021 13.8 0.0 1.0 1 0 0 1 1 1 0 Amidase DUF2637 PF10935.8 KFX87290.1 - 0.038 13.9 2.4 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) SecD_SecF PF02355.16 KFX87290.1 - 0.076 12.4 0.8 0.16 11.4 0.8 1.5 1 0 0 1 1 1 0 Protein export membrane protein DUF4231 PF14015.6 KFX87290.1 - 2.1 8.8 4.5 42 4.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Beta_elim_lyase PF01212.21 KFX87291.1 - 5.3e-50 170.3 0.0 8e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Methyltransf_23 PF13489.6 KFX87291.1 - 1.2e-06 28.5 0.0 0.00091 19.1 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87291.1 - 0.0003 21.4 0.2 0.0059 17.3 0.1 2.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX87291.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 KFX87291.1 - 0.014 15.2 0.0 0.42 10.4 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 KFX87291.1 - 0.02 14.2 0.0 0.099 11.9 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 KFX87291.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFX87291.1 - 0.079 13.6 0.0 13 6.5 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFX87291.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.16 KFX87292.1 - 6.8e-32 110.7 38.1 8.5e-32 110.4 38.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane_2 PF06472.15 KFX87293.1 - 2.7e-103 345.1 1.6 4.6e-103 344.3 1.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFX87293.1 - 1.4e-17 64.5 0.0 3.3e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFX87293.1 - 0.00023 21.1 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX87293.1 - 0.014 16.0 0.1 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KFX87293.1 - 0.057 12.9 0.2 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX87293.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KFX87293.1 - 0.088 12.6 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX87293.1 - 0.11 12.9 0.2 0.67 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KFX87293.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KFX87293.1 - 0.21 11.0 0.1 0.6 9.5 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf-CSL PF05207.13 KFX87294.1 - 4.1e-21 74.5 0.2 4.8e-21 74.2 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Terminase_GpA PF05876.12 KFX87294.1 - 0.24 9.9 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Frataxin_Cyay PF01491.16 KFX87295.1 - 1.6e-38 131.1 0.0 2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.20 KFX87296.1 - 1.9e-41 141.4 0.1 6.8e-41 139.5 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PurL_C PF16904.5 KFX87297.1 - 0.13 12.6 0.6 0.27 11.6 0.5 1.6 1 1 1 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus Peptidase_M48_N PF16491.5 KFX87297.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices tRNA-synt_1 PF00133.22 KFX87298.1 - 4.9e-38 130.8 0.0 2.7e-27 95.3 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFX87298.1 - 6.2e-16 58.1 0.0 1.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFX87298.1 - 7e-12 45.6 0.2 1.3e-11 44.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFX87298.1 - 9.6e-08 31.7 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KFX87298.1 - 0.1 12.1 0.8 9.8 5.6 0.0 2.8 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 DUF4499 PF14934.6 KFX87299.1 - 0.035 14.4 2.2 0.046 14.1 2.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Striatin PF08232.12 KFX87300.1 - 0.0026 18.4 3.8 0.0041 17.7 3.8 1.3 1 0 0 1 1 1 1 Striatin family Spc7 PF08317.11 KFX87300.1 - 0.019 13.9 0.2 0.024 13.5 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KFX87300.1 - 0.028 14.7 0.5 0.028 14.7 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFX87300.1 - 0.033 14.8 0.1 0.092 13.4 0.1 1.8 1 0 0 1 1 1 0 SlyX DUF4855 PF16147.5 KFX87300.1 - 0.043 12.9 0.2 0.14 11.2 0.0 1.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4855) Bromodomain PF00439.25 KFX87301.1 - 1.9e-07 31.1 0.1 2.7e-06 27.4 0.0 2.6 2 1 0 2 2 2 1 Bromodomain APH PF01636.23 KFX87302.1 - 7.8e-11 42.3 0.0 4.9e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX87302.1 - 0.0019 17.8 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase HTH_46 PF15977.5 KFX87302.1 - 0.1 12.6 0.1 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Fructosamin_kin PF03881.14 KFX87302.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.16 KFX87303.1 - 8.4e-37 126.9 32.1 8.4e-37 126.9 32.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ketoacyl-synt PF00109.26 KFX87304.1 - 3.3e-80 269.3 0.0 5.4e-80 268.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFX87304.1 - 6.7e-73 245.4 0.8 4.8e-71 239.3 0.0 2.9 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFX87304.1 - 1.3e-40 139.8 0.0 5.3e-39 134.6 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX87304.1 - 3e-35 120.8 0.0 8.2e-35 119.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KFX87304.1 - 1.3e-27 95.9 6.2 5.9e-13 49.0 0.2 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KFX87304.1 - 2.4e-26 93.3 0.0 6.3e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.6 KFX87304.1 - 1.5e-12 47.4 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFX87304.1 - 1.2e-06 28.9 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KFX87304.1 - 4.8e-06 27.3 0.6 8.1e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KFX87304.1 - 0.0011 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain AflR PF08493.10 KFX87304.1 - 0.0033 17.0 5.0 0.0061 16.1 5.0 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein DUF2974 PF11187.8 KFX87304.1 - 0.042 13.4 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ABC2_membrane PF01061.24 KFX87305.1 - 1.3e-28 99.9 28.6 1.3e-28 99.9 28.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFX87305.1 - 9e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFX87305.1 - 3.4e-05 23.8 0.8 0.058 13.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX87305.1 - 9e-05 22.4 0.1 0.00091 19.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFX87305.1 - 0.00029 20.5 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFX87305.1 - 0.00037 20.8 0.0 0.00092 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX87305.1 - 0.0004 20.8 0.0 0.00069 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KFX87305.1 - 0.0018 17.8 0.5 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KFX87305.1 - 0.0019 17.0 0.5 0.013 14.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFX87305.1 - 0.007 16.8 0.2 0.099 13.1 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFX87305.1 - 0.0075 16.8 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFX87305.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFX87305.1 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFX87305.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KFX87305.1 - 0.044 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFX87305.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFX87305.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFX87305.1 - 0.11 13.0 0.2 0.28 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KFX87305.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 KFX87305.1 - 0.16 11.0 25.4 0.63 9.1 25.4 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ACOX PF01756.19 KFX87306.1 - 1.8e-44 151.5 0.2 3.8e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFX87306.1 - 1.7e-24 86.8 0.0 3.9e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFX87306.1 - 8.3e-13 48.4 0.0 2.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFX87306.1 - 3e-05 24.3 0.6 0.0021 18.3 0.6 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Thy1 PF02511.15 KFX87306.1 - 0.013 15.3 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF1657 PF07870.11 KFX87306.1 - 0.6 10.0 3.1 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Trypan_PARP PF05887.11 KFX87313.1 - 6.8 6.7 22.2 6.6 6.7 18.5 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) ABC2_membrane PF01061.24 KFX87315.1 - 1.1e-80 270.0 60.4 3.1e-41 141.1 26.6 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX87315.1 - 3.3e-33 115.1 0.0 2.7e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX87315.1 - 3.7e-32 110.1 9.0 2.3e-29 101.1 0.1 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX87315.1 - 2.8e-13 50.3 0.1 6.7e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KFX87315.1 - 4.8e-06 26.6 0.2 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KFX87315.1 - 5e-06 25.9 40.7 0.00022 20.5 16.9 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KFX87315.1 - 1.4e-05 25.6 0.0 0.01 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFX87315.1 - 2.8e-05 24.1 0.0 0.37 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KFX87315.1 - 7.7e-05 22.4 0.1 0.00043 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX87315.1 - 7.9e-05 23.1 0.1 0.071 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KFX87315.1 - 0.00012 22.3 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX87315.1 - 0.00054 19.7 0.9 0.052 13.3 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KFX87315.1 - 0.00085 19.6 0.2 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KFX87315.1 - 0.0018 18.7 2.0 0.56 10.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KFX87315.1 - 0.0059 16.1 0.0 0.99 8.8 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KFX87315.1 - 0.02 15.3 0.0 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX87315.1 - 0.02 15.1 1.5 2.4 8.4 0.1 3.5 4 0 0 4 4 3 0 AAA domain cobW PF02492.19 KFX87315.1 - 0.024 14.2 0.9 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFX87315.1 - 0.027 14.4 1.3 4.1 7.3 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KFX87315.1 - 0.044 13.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX87315.1 - 0.055 13.2 0.8 18 5.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 KFX87315.1 - 0.061 13.2 0.0 7.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 KFX87315.1 - 0.1 12.6 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3671 PF12420.8 KFX87315.1 - 4.1 7.5 5.3 17 5.6 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function Zn_clus PF00172.18 KFX87316.1 - 4.6e-07 29.9 12.7 4.6e-07 29.9 12.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KFX87316.1 - 0.57 10.7 7.7 1.2 9.7 7.7 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Zn_clus PF00172.18 KFX87318.1 - 2.9e-07 30.5 11.3 6.4e-07 29.4 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alanine_zipper PF11839.8 KFX87323.1 - 0.72 10.3 16.3 1 9.8 16.3 1.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein UBM PF14377.6 KFX87324.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin binding region RNA12 PF10443.9 KFX87325.1 - 6.1e-167 555.9 0.6 1.5e-166 554.6 0.6 1.7 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 KFX87325.1 - 0.0006 19.6 0.0 0.0038 17.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KFX87325.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Picorna_P3A PF06363.11 KFX87325.1 - 0.011 15.6 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Picornaviridae P3A protein AAA_16 PF13191.6 KFX87325.1 - 0.024 15.0 0.6 0.21 12.0 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain Complex1_49kDa PF00346.19 KFX87329.1 - 3.3e-124 413.4 0.0 4.6e-124 412.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KFX87329.1 - 0.014 14.3 0.0 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 KFX87330.1 - 2.1e-25 89.3 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFX87330.1 - 8.5e-22 76.4 0.0 1.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 KFX87331.1 - 3.4e-62 210.0 0.0 4.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFX87331.1 - 7.8e-29 99.7 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KFX87331.1 - 0.0019 18.3 0.7 0.0037 17.3 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX87331.1 - 0.033 13.8 0.2 0.056 13.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 KFX87331.1 - 0.056 14.1 0.6 0.21 12.2 0.2 2.2 2 0 0 2 2 2 0 PglD N-terminal domain Ecm33 PF12454.8 KFX87331.1 - 0.083 13.0 0.7 0.21 11.8 0.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 KFX87331.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 KFX87331.1 - 0.13 13.1 0.0 0.38 11.6 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain CRC_subunit PF08624.10 KFX87331.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit Telomere_reg-2 PF10193.9 KFX87332.1 - 1.8e-35 121.7 0.0 4.7e-35 120.3 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Ras PF00071.22 KFX87334.1 - 4.9e-49 166.0 0.0 6.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX87334.1 - 1.8e-29 102.4 0.1 4.5e-29 101.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX87334.1 - 2.5e-10 40.1 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFX87334.1 - 0.00017 21.9 0.1 0.00089 19.6 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KFX87334.1 - 0.00033 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX87334.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFX87334.1 - 0.0085 15.3 1.4 0.61 9.2 0.1 2.6 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 KFX87334.1 - 0.024 14.1 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KFX87334.1 - 0.028 14.3 0.2 7.4 6.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KFX87334.1 - 0.04 13.4 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KFX87334.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFX87334.1 - 0.071 12.8 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX87334.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFX87334.1 - 0.13 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF212 PF02681.14 KFX87335.1 - 0.0076 16.4 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 KFX87335.1 - 0.028 14.2 3.4 0.086 12.6 1.2 2.7 2 1 1 3 3 3 0 PAP2 superfamily Nas2_N PF18265.1 KFX87336.1 - 2.6e-28 97.8 0.0 3.7e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 KFX87336.1 - 8.6e-09 35.6 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFX87336.1 - 2.3e-08 33.7 0.3 4.1e-08 32.9 0.3 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFX87336.1 - 0.00016 22.0 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KFX87336.1 - 0.0013 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DLH PF01738.18 KFX87337.1 - 4.1e-34 118.0 0.1 4.7e-34 117.8 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3530 PF12048.8 KFX87337.1 - 0.0017 17.8 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 KFX87337.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cys_Met_Meta_PP PF01053.20 KFX87339.1 - 2.3e-55 187.7 0.0 1.3e-54 185.2 0.0 2.1 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-CCCH PF00642.24 KFX87339.1 - 1.3e-06 28.2 2.5 1.3e-06 28.2 2.5 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFX87339.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFX87339.1 - 0.023 14.8 3.3 0.023 14.8 3.3 2.8 3 0 0 3 3 3 0 Zinc finger domain DUF4131 PF13567.6 KFX87339.1 - 0.026 14.2 0.0 0.2 11.3 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Aminotran_5 PF00266.19 KFX87339.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HATPase_c_3 PF13589.6 KFX87340.1 - 5.5e-16 58.6 0.1 1.1e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KFX87340.1 - 2.7e-11 43.2 0.0 5.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFX87340.1 - 3.7e-07 30.6 0.1 1.2e-06 29.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase tRNA-synt_1 PF00133.22 KFX87341.1 - 1.5e-218 726.9 1.3 1.7e-217 723.5 1.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX87341.1 - 5.3e-31 107.6 0.7 1.1e-30 106.6 0.7 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX87341.1 - 2.1e-15 56.4 0.1 1.3e-07 30.8 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFX87341.1 - 1.7e-13 50.5 0.2 1.8e-09 37.3 0.0 3.1 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KFX87341.1 - 0.00073 19.8 5.4 0.00073 19.8 5.4 2.7 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KFX87341.1 - 0.0031 16.9 0.0 0.029 13.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Fusion_gly PF00523.18 KFX87341.1 - 0.022 13.0 0.1 0.035 12.4 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 PepSY PF03413.19 KFX87341.1 - 0.059 13.9 0.0 0.42 11.2 0.0 2.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CCDC53 PF10152.9 KFX87341.1 - 2.7 8.4 7.4 7.1 7.0 7.4 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Chitin_synth_2 PF03142.15 KFX87342.1 - 7.2e-291 965.4 0.1 1e-290 964.9 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KFX87342.1 - 7.3e-14 52.1 2.6 2.1e-13 50.6 2.6 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFX87342.1 - 3.4e-10 40.2 0.0 6.8e-09 35.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX87342.1 - 0.0038 17.1 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFX87342.1 - 0.015 14.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 Sel1 PF08238.12 KFX87343.1 - 3.7e-38 129.1 33.9 5.4e-06 26.9 0.6 8.2 8 0 0 8 8 8 7 Sel1 repeat FYVE PF01363.21 KFX87344.1 - 2.8e-21 75.4 1.4 2.8e-21 75.4 1.4 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KFX87344.1 - 9.9e-07 28.5 2.9 9.9e-07 28.5 2.9 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX87344.1 - 2.8e-06 27.5 4.4 2.8e-06 27.5 4.4 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KFX87344.1 - 7.7e-05 22.5 2.4 7.7e-05 22.5 2.4 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX87344.1 - 0.00012 21.8 5.7 0.00012 21.8 5.7 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFX87344.1 - 0.0012 18.8 3.5 0.0012 18.8 3.5 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING-like PF08746.11 KFX87344.1 - 0.018 15.3 2.5 0.018 15.3 2.5 2.8 3 0 0 3 3 2 0 RING-like domain Rad50_zn_hook PF04423.14 KFX87344.1 - 0.093 12.6 3.2 0.094 12.6 0.6 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 KFX87344.1 - 0.13 12.3 7.4 1.8 8.6 4.6 2.8 2 0 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 KFX87344.1 - 0.19 11.9 10.8 0.11 12.7 3.0 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-HC5HC2H PF13771.6 KFX87344.1 - 5.1 7.4 10.3 3.5 7.9 1.3 3.0 3 0 0 3 3 3 0 PHD-like zinc-binding domain DUF3605 PF12239.8 KFX87345.1 - 2.1e-55 187.3 0.2 2.5e-55 187.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KFX87346.1 - 1e-21 77.6 0.1 1.2e-17 64.5 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase FAR1 PF03101.15 KFX87346.1 - 0.007 17.0 0.5 0.014 16.1 0.5 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Fungal_trans PF04082.18 KFX87347.1 - 2.2e-15 56.4 0.0 3.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3306 PF11748.8 KFX87347.1 - 0.019 15.8 0.2 0.045 14.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ING PF12998.7 KFX87348.1 - 7e-20 71.5 1.7 1e-19 71.0 1.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFX87348.1 - 0.00014 21.7 7.7 0.00025 20.9 7.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.18 KFX87348.1 - 0.029 13.7 0.9 0.029 13.7 0.9 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-HC5HC2H PF13771.6 KFX87348.1 - 0.17 12.1 1.1 0.38 11.0 1.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hist_deacetyl PF00850.19 KFX87349.1 - 3e-81 273.2 0.1 4.8e-81 272.6 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain tRNA-synt_His PF13393.6 KFX87350.1 - 7.8e-38 130.5 0.0 2.4e-31 109.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFX87350.1 - 1.3e-11 44.4 0.0 2.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFX87350.1 - 2.3e-05 24.4 0.0 3.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KFX87350.1 - 0.0041 16.3 0.0 0.015 14.4 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 KFX87350.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Homeodomain PF00046.29 KFX87351.1 - 7.9e-14 51.3 4.1 1.5e-13 50.4 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KFX87352.1 - 2.5e-69 233.6 0.0 3.5e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87352.1 - 6.8e-37 127.2 0.0 1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX87352.1 - 8.8e-09 35.1 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KFX87352.1 - 0.0035 16.9 0.1 0.27 10.7 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KFX87352.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 KFX87353.1 - 3.7e-24 85.0 0.0 4.3e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX87353.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFX87353.1 - 0.0026 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KFX87353.1 - 0.0089 16.3 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain NMO PF03060.15 KFX87357.1 - 1.1e-52 179.5 0.3 1.5e-51 175.8 0.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFX87357.1 - 5.5e-15 55.2 0.0 2.4e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFX87357.1 - 0.00046 19.3 0.1 0.00083 18.5 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFX87357.1 - 0.011 15.0 0.2 0.025 13.7 0.2 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 KFX87357.1 - 0.082 12.4 0.2 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF1902 PF08972.11 KFX87357.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) NanE PF04131.14 KFX87357.1 - 0.21 10.7 0.9 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Ferric_reduct PF01794.19 KFX87358.1 - 1.3e-21 77.0 14.0 1e-19 70.9 9.3 2.7 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX87358.1 - 4.1e-18 66.0 0.0 6.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX87358.1 - 2e-05 24.7 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DND1_DSRM PF14709.7 KFX87360.1 - 0.0076 16.5 0.2 0.077 13.3 0.2 2.1 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KFX87360.1 - 0.019 15.7 0.1 0.039 14.7 0.1 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif RPA_interact_N PF14766.6 KFX87360.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Ribosomal_S7 PF00177.21 KFX87361.1 - 9.9e-26 90.2 0.0 1.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e APH PF01636.23 KFX87366.1 - 2.1e-16 60.6 0.0 1.4e-15 57.9 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX87366.1 - 5.3e-07 29.4 0.0 8.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFX87366.1 - 0.0038 16.8 0.7 0.034 13.7 0.0 2.4 3 0 0 3 3 3 1 RIO1 family MFS_1 PF07690.16 KFX87367.1 - 4.5e-29 101.5 30.7 2.1e-28 99.3 30.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF485 PF04341.12 KFX87367.1 - 3.6 7.6 7.7 2.8 8.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function, DUF485 p450 PF00067.22 KFX87368.1 - 6.8e-89 298.7 0.0 8.7e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KFX87369.1 - 1.7e-15 57.2 18.1 0.00088 20.0 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87369.1 - 2e-05 24.8 0.0 3.3 8.1 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX87369.1 - 0.036 13.0 0.0 0.49 9.3 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 KFX87369.1 - 0.043 13.5 7.8 0.09 12.5 7.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleoporin_N PF08801.11 KFX87369.1 - 0.1 11.3 1.0 0.44 9.2 0.1 2.2 2 1 0 2 2 2 0 Nup133 N terminal like eIF2A PF08662.11 KFX87369.1 - 0.13 12.1 0.0 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.14 KFX87370.1 - 1.9e-62 211.0 12.7 7.3e-61 205.9 7.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA LysE PF01810.18 KFX87370.1 - 0.00054 19.5 1.9 0.00054 19.5 1.9 3.0 3 1 1 4 4 4 2 LysE type translocator EamA PF00892.20 KFX87370.1 - 0.0015 18.7 2.2 0.0015 18.7 2.2 3.9 3 1 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KFX87370.1 - 0.0096 15.5 5.7 0.061 12.8 0.2 2.3 1 1 1 2 2 2 1 Solute carrier family 35 DUF418 PF04235.12 KFX87370.1 - 0.27 11.1 4.7 0.88 9.5 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF418) TssN PF17555.2 KFX87370.1 - 1.7 8.0 8.5 2.9 7.2 8.5 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN TPR_2 PF07719.17 KFX87371.1 - 0.00024 21.0 3.5 0.45 10.8 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX87371.1 - 0.0053 17.2 0.2 0.46 11.0 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX87371.1 - 0.01 16.1 1.3 0.93 9.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 KFX87371.1 - 0.013 15.0 1.1 0.046 13.2 0.0 2.2 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 KFX87371.1 - 0.035 13.9 0.1 6.3 6.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX87371.1 - 0.092 13.4 5.2 1.6 9.4 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX87371.1 - 0.12 12.4 1.3 2.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX87371.1 - 1.7 9.7 4.6 32 5.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HMG_box PF00505.19 KFX87373.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box RCR PF12273.8 KFX87373.1 - 0.052 14.2 1.1 0.12 13.0 1.1 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HMG_box_2 PF09011.10 KFX87373.1 - 0.091 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain CCDC106 PF15794.5 KFX87373.1 - 0.27 10.9 3.2 0.84 9.3 3.2 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNase_HII PF01351.18 KFX87378.1 - 1.7e-31 109.6 0.0 8e-25 87.8 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII T4-Gluco-transf PF09198.10 KFX87378.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase RHD3 PF05879.12 KFX87379.1 - 0 1045.0 0.0 0 1044.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KFX87379.1 - 1.2e-07 31.3 0.1 2.1e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KFX87379.1 - 2.2e-05 24.6 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFX87379.1 - 0.00022 21.3 0.0 0.00052 20.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFX87379.1 - 0.0055 17.0 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain DSBA PF01323.20 KFX87379.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Asp PF00026.23 KFX87380.1 - 1.1e-69 235.3 5.4 1.3e-69 235.1 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX87380.1 - 2e-12 47.7 4.9 1.8e-06 28.3 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX87380.1 - 0.00076 20.1 0.6 0.055 14.1 0.2 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX87380.1 - 0.02 15.4 0.3 0.44 11.1 0.2 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ank_4 PF13637.6 KFX87381.1 - 8.9e-05 23.0 0.0 0.84 10.3 0.0 4.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) F-box-like PF12937.7 KFX87381.1 - 0.0023 17.8 1.0 0.0095 15.8 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFX87381.1 - 0.0027 17.5 0.6 0.0062 16.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain Ank_3 PF13606.6 KFX87381.1 - 0.047 14.2 1.0 3.6e+02 2.3 0.0 5.5 7 0 0 7 7 7 0 Ankyrin repeat Sacchrp_dh_NADP PF03435.18 KFX87382.1 - 6.2e-20 71.8 0.8 6.2e-20 71.8 0.8 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KFX87382.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFX87382.1 - 0.0028 16.9 0.1 0.0044 16.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KFX87382.1 - 0.005 16.8 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 KR domain Aldolase PF01081.19 KFX87382.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase NmrA PF05368.13 KFX87382.1 - 0.034 13.7 0.2 0.071 12.7 0.2 1.6 1 0 0 1 1 1 0 NmrA-like family Rootletin PF15035.6 KFX87384.1 - 0.0017 18.4 21.5 0.16 12.0 1.3 2.7 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.15 KFX87384.1 - 0.014 15.8 8.8 0.014 15.8 8.8 2.1 1 1 1 2 2 2 0 Fez1 CENP-H PF05837.12 KFX87384.1 - 0.029 14.8 4.8 0.029 14.8 4.8 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) WbqC PF08889.11 KFX87384.1 - 0.23 11.3 1.1 0.29 11.0 1.1 1.1 1 0 0 1 1 1 0 WbqC-like protein family ZapB PF06005.12 KFX87384.1 - 0.26 11.8 28.5 2.4 8.6 3.2 4.1 2 2 1 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 KFX87384.1 - 1 9.6 8.7 1.8 8.8 1.7 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4140 PF13600.6 KFX87384.1 - 1.1 9.7 13.6 0.44 11.0 4.0 2.9 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seadorna_VP6 PF07407.11 KFX87384.1 - 1.4 7.8 4.9 0.25 10.2 1.5 1.5 2 0 0 2 2 2 0 Seadornavirus VP6 protein HIP1_clath_bdg PF16515.5 KFX87384.1 - 1.6 9.4 21.1 3.9 8.1 6.0 3.2 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SPT16 PF08644.11 KFX87384.1 - 3.3 7.9 10.8 0.51 10.5 4.5 2.0 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) LPP PF04728.13 KFX87384.1 - 3.8 8.0 13.5 0.46 10.9 1.3 3.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 KFX87384.1 - 4 7.5 22.5 2.6 8.1 16.2 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Cnn_1N PF07989.11 KFX87384.1 - 6.7 6.9 18.7 14 6.0 3.3 3.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 KFX87384.1 - 7.7 6.8 13.9 2.6 8.3 0.6 3.2 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Uso1_p115_C PF04871.13 KFX87384.1 - 8 6.9 21.5 0.12 12.7 7.5 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5320 PF17253.2 KFX87384.1 - 8.3 7.5 6.8 1.9 9.6 0.7 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5320) MFS_1 PF07690.16 KFX87385.1 - 8.2e-34 117.1 52.9 2.5e-33 115.5 52.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_jaz PF12171.8 KFX87386.1 - 8.6e-05 22.7 0.8 0.00015 21.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX87386.1 - 0.0032 17.8 0.1 0.0057 17.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFX87386.1 - 0.0044 17.1 1.7 0.0078 16.3 1.7 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 KFX87386.1 - 0.056 13.9 0.5 0.095 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3449 PF11931.8 KFX87386.1 - 0.11 12.3 1.9 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) FAD_binding_1 PF00667.20 KFX87390.1 - 9e-62 208.5 0.0 1.4e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KFX87390.1 - 3.7e-33 114.7 1.0 7e-33 113.8 1.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFX87390.1 - 1.1e-20 74.2 0.0 2.3e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FSH1 PF03959.13 KFX87397.1 - 1.8e-33 116.0 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KFX87397.1 - 0.00076 19.0 0.4 0.88 9.0 0.5 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 KFX87397.1 - 0.042 13.5 0.0 0.84 9.2 0.1 2.5 2 1 0 3 3 3 0 alpha/beta hydrolase fold AXE1 PF05448.12 KFX87397.1 - 0.075 11.7 0.6 1 8.0 0.2 2.3 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) PE-PPE PF08237.11 KFX87397.1 - 0.18 11.3 0.2 0.53 9.8 0.1 1.8 2 1 0 2 2 2 0 PE-PPE domain FAD_binding_3 PF01494.19 KFX87400.1 - 4.9e-13 49.1 0.0 1.4e-07 31.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFX87400.1 - 0.00061 20.0 0.1 0.0015 18.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX87400.1 - 0.0031 16.8 0.3 0.0082 15.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX87400.1 - 0.023 13.8 0.1 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 KFX87400.1 - 0.038 13.6 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFX87400.1 - 0.04 13.0 0.0 0.27 10.2 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFX87400.1 - 0.068 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX87400.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Poxvirus_B22R_C PF13168.6 KFX87400.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Thi4 PF01946.17 KFX87400.1 - 0.14 11.4 0.1 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lipoxygenase PF00305.19 KFX87402.1 - 1.1e-52 179.4 2.9 4.1e-51 174.2 2.9 2.0 1 1 0 1 1 1 1 Lipoxygenase ERG4_ERG24 PF01222.17 KFX87403.1 - 0.021 13.6 1.2 0.031 13.0 1.2 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_25 PF13649.6 KFX87405.1 - 1.7e-07 31.8 0.0 7.3e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87405.1 - 2e-05 24.5 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87405.1 - 5.1e-05 23.1 0.1 0.00039 20.2 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFX87405.1 - 0.00058 19.7 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KFX87405.1 - 0.0022 18.7 0.0 0.022 15.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KFX87405.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW GCD14 PF08704.10 KFX87405.1 - 0.0052 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KFX87405.1 - 0.0079 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFX87405.1 - 0.024 14.7 0.0 0.13 12.4 0.0 2.1 1 1 0 2 2 2 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 KFX87405.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Zn_clus PF00172.18 KFX87406.1 - 3.6e-06 27.0 11.6 3.6e-06 27.0 11.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KFX87407.1 - 3.3e-14 53.0 0.0 5.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX87407.1 - 3.3e-12 46.6 0.0 7.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX87407.1 - 2.9e-10 40.2 0.0 4.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX87407.1 - 4.6e-09 36.5 0.1 2.1e-08 34.3 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX87407.1 - 6e-09 36.0 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX87407.1 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFX87407.1 - 0.0063 17.2 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 KFX87407.1 - 0.01 16.4 0.0 0.049 14.2 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Fungal_trans_2 PF11951.8 KFX87408.1 - 6.7e-64 216.1 1.4 1e-63 215.5 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain E3_UbLigase_R4 PF13764.6 KFX87408.1 - 5.4 5.0 7.0 4.2 5.4 5.0 1.6 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 adh_short PF00106.25 KFX87409.1 - 2.9e-19 69.3 0.0 4.3e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX87409.1 - 7e-12 45.4 0.0 9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX87409.1 - 3.4e-05 23.8 0.0 0.00058 19.8 0.0 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFX87409.1 - 0.033 14.1 0.1 0.093 12.6 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding VWA_2 PF13519.6 KFX87410.1 - 0.002 18.7 0.0 0.0059 17.2 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX87410.1 - 0.053 13.8 0.0 0.22 11.7 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain Fungal_trans PF04082.18 KFX87411.1 - 6.9e-14 51.5 0.0 1.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87411.1 - 6.6e-09 35.7 8.8 6.6e-09 35.7 8.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neuromodulin PF06614.11 KFX87411.1 - 0.18 12.0 3.4 0.33 11.1 3.4 1.4 1 0 0 1 1 1 0 Neuromodulin NmrA PF05368.13 KFX87412.1 - 2.4e-29 102.5 0.9 2.9e-29 102.3 0.9 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX87412.1 - 2.2e-19 70.0 0.1 7.3e-19 68.4 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFX87412.1 - 1.5e-05 24.6 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFX87412.1 - 0.00069 20.1 0.8 0.0017 18.8 0.2 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KFX87412.1 - 0.0053 16.7 0.9 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KFX87412.1 - 0.0075 15.3 1.1 0.012 14.6 0.3 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KFX87412.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX87412.1 - 0.033 14.3 2.8 0.061 13.5 0.5 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PglD_N PF17836.1 KFX87412.1 - 0.036 14.7 0.7 0.089 13.4 0.7 1.7 1 0 0 1 1 1 0 PglD N-terminal domain Polysacc_synt_2 PF02719.15 KFX87412.1 - 0.058 12.5 0.1 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MANEC PF07502.14 KFX87413.1 - 7.9e-06 26.1 4.6 0.078 13.3 0.0 2.5 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 KFX87413.1 - 0.0016 18.3 17.1 0.021 14.8 1.0 3.2 2 1 0 2 2 2 2 PAN domain PAN_3 PF08277.12 KFX87413.1 - 1.3 8.8 11.4 9.6 6.1 6.7 2.9 2 1 0 2 2 2 0 PAN-like domain NAD_binding_10 PF13460.6 KFX87414.1 - 4.7e-10 39.7 0.0 8.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX87414.1 - 1.4e-07 31.4 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFX87414.1 - 0.011 16.1 0.7 0.043 14.3 0.3 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX87414.1 - 0.014 15.5 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KFX87414.1 - 0.061 12.8 0.3 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Antig_Caf1 PF09255.10 KFX87414.1 - 0.075 13.1 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Caf1 Capsule antigen GFO_IDH_MocA PF01408.22 KFX87414.1 - 0.093 13.6 0.1 0.79 10.6 0.1 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.10 KFX87414.1 - 0.14 12.1 0.2 0.26 11.2 0.2 1.6 1 1 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.8 KFX87415.1 - 2.3e-62 211.0 2.2 3.2e-62 210.6 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87415.1 - 1.4e-07 31.5 5.2 1.4e-07 31.5 5.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFX87416.1 - 3.2e-76 257.0 20.2 3.9e-76 256.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87416.1 - 3.9e-23 82.0 40.1 4.7e-22 78.4 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX87416.1 - 3.8e-06 25.7 14.9 3e-05 22.8 3.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein GFA PF04828.14 KFX87417.1 - 3e-18 66.0 0.5 6.7e-18 64.8 0.5 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 KFX87417.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.11 KFX87417.1 - 0.12 12.5 2.5 3.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Chondroitinas_B PF14592.6 KFX87418.1 - 2.9e-07 29.7 0.0 4.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Chondroitinase B Beta_helix PF13229.6 KFX87418.1 - 6.6e-07 29.3 16.1 5.9e-05 23.0 6.7 2.4 1 1 1 2 2 2 2 Right handed beta helix region GMC_oxred_C PF05199.13 KFX87419.1 - 1.4e-13 51.6 0.0 3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_hydro_43 PF04616.14 KFX87419.1 - 1.1e-11 44.6 0.1 1.6e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.18 KFX87420.1 - 7.6e-15 54.7 0.0 1.1e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87420.1 - 0.028 14.6 3.8 0.062 13.4 3.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFX87421.1 - 2.4e-98 330.0 29.0 3e-98 329.6 29.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87421.1 - 7.8e-23 81.0 28.4 7.8e-23 81.0 28.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KFX87421.1 - 0.023 13.1 10.5 0.034 12.5 5.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Sulfatase PF00884.23 KFX87422.1 - 1.7e-43 149.2 0.2 8e-41 140.4 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFX87422.1 - 8.4e-07 28.9 0.1 2.9e-05 23.8 0.1 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFX87422.1 - 9.2e-06 25.9 1.4 9.2e-06 25.9 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFX87422.1 - 0.038 14.7 0.0 0.081 13.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KFX87422.1 - 0.078 12.9 0.2 0.33 10.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function An_peroxidase PF03098.15 KFX87422.1 - 0.12 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Animal haem peroxidase Beta_helix PF13229.6 KFX87423.1 - 1.5e-12 47.6 15.6 6.2e-08 32.7 6.4 2.9 2 1 0 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 KFX87423.1 - 0.013 14.8 4.2 0.24 10.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) zf-C2H2_2 PF12756.7 KFX87424.1 - 2.8e-30 104.6 11.9 1.8e-22 79.6 3.0 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFX87424.1 - 0.0012 19.1 1.4 0.0012 19.1 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TFIIIC PF12660.7 KFX87424.1 - 0.0026 17.7 0.0 0.01 15.8 0.0 2.0 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex zf-met PF12874.7 KFX87424.1 - 0.0034 17.7 10.3 0.54 10.7 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type F-box-like PF12937.7 KFX87424.1 - 0.0034 17.2 0.3 0.0094 15.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF2256 PF10013.9 KFX87424.1 - 0.021 15.0 0.5 0.48 10.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_4 PF13894.6 KFX87424.1 - 0.06 14.2 0.5 0.06 14.2 0.5 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf_Hakai PF18408.1 KFX87424.1 - 0.091 12.5 0.4 0.26 11.0 0.4 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain DUF629 PF04780.12 KFX87424.1 - 0.35 9.3 2.1 9.3 4.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-CHY PF05495.12 KFX87424.1 - 0.46 11.0 2.8 0.66 10.5 0.8 2.3 2 0 0 2 2 2 0 CHY zinc finger TMEM132D_C PF15706.5 KFX87425.1 - 0.0025 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM154 PF15102.6 KFX87425.1 - 0.0035 17.2 0.4 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family TFIIA PF03153.13 KFX87425.1 - 1.2 9.0 18.2 2.6 7.9 18.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 KFX87425.1 - 9.7 6.0 16.4 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 SPX domain Adeno_E3_CR2 PF02439.15 KFX87426.1 - 0.00014 21.6 0.4 0.00026 20.7 0.4 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Asp PF00026.23 KFX87426.1 - 0.0043 16.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Adeno_E3 PF06040.11 KFX87426.1 - 0.14 12.4 0.9 7.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Adenovirus E3 protein NmrA PF05368.13 KFX87430.1 - 5.5e-05 22.8 0.0 9.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX87430.1 - 8.3e-05 22.5 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KFX87430.1 - 0.00024 21.5 0.0 0.0004 20.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KFX87430.1 - 0.00044 19.8 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX87430.1 - 0.005 16.0 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Cutinase PF01083.22 KFX87432.1 - 4.6e-50 170.0 10.6 5.3e-50 169.8 10.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFX87432.1 - 2.7e-05 23.9 0.6 4.3e-05 23.2 0.6 1.4 1 0 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.8 KFX87432.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) GHMP_kinases_N PF00288.26 KFX87432.1 - 0.14 12.4 5.0 1.3 9.3 3.2 2.6 2 0 0 2 2 2 0 GHMP kinases N terminal domain Response_reg PF00072.24 KFX87433.1 - 2.4e-21 76.0 0.0 1.2e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KFX87433.1 - 1e-20 74.3 0.2 1.9e-20 73.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX87433.1 - 1.1e-10 41.4 0.4 2.8e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MS_channel PF00924.18 KFX87433.1 - 0.03 13.9 0.0 0.095 12.2 0.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel Abhydrolase_6 PF12697.7 KFX87434.1 - 4.8e-19 69.8 0.0 6.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFX87434.1 - 0.002 17.6 0.1 0.0032 17.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 KFX87434.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein VirB8 PF04335.13 KFX87434.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 VirB8 protein Abhydrolase_1 PF00561.20 KFX87434.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_2 PF01674.18 KFX87434.1 - 0.071 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) DUF3089 PF11288.8 KFX87434.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Cys_Met_Meta_PP PF01053.20 KFX87435.1 - 1.7e-135 451.4 0.0 2e-135 451.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX87435.1 - 2.2e-07 30.4 0.0 3.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX87435.1 - 1e-05 24.7 0.0 6.7e-05 22.0 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 KFX87435.1 - 3.1e-05 22.7 0.0 0.0001 21.0 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KFX87435.1 - 0.017 14.5 0.0 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KFX87435.1 - 0.04 13.2 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 KFX87435.1 - 0.061 13.2 0.0 0.91 9.4 0.0 2.5 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus TQ PF18202.1 KFX87435.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 T-Q ester bond containing domain POTRA_2 PF08479.11 KFX87435.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type PGI PF00342.19 KFX87436.1 - 5.2e-238 790.5 2.9 5.9e-238 790.3 2.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase HAD_2 PF13419.6 KFX87439.1 - 3.2e-09 37.1 0.0 6e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX87439.1 - 1e-07 32.5 0.0 2e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX87439.1 - 0.0068 16.8 0.1 0.1 13.0 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase GGACT PF06094.12 KFX87441.1 - 1.4e-14 54.7 0.0 1.8e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aldose_epim PF01263.20 KFX87442.1 - 1e-59 202.3 0.0 1.4e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.8 KFX87443.1 - 4.1e-34 116.4 0.1 4.1e-34 116.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.12 KFX87444.1 - 1.2e-160 534.5 0.0 1.9e-160 533.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFX87444.1 - 2.1e-79 267.1 0.2 3.6e-79 266.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain NMT1 PF09084.11 KFX87444.1 - 5.5e-77 258.5 0.0 1.6e-76 257.0 0.0 1.8 2 0 0 2 2 2 1 NMT1/THI5 like DNA_pol_B PF00136.21 KFX87444.1 - 1.3e-14 53.8 0.1 5.8e-13 48.4 0.1 3.2 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFX87444.1 - 4.3e-09 36.4 0.3 1.3e-08 34.8 0.3 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFX87444.1 - 4.3e-06 26.8 0.0 1.9e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 RNase_H superfamily NMT1_2 PF13379.6 KFX87444.1 - 0.066 12.9 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 NMT1-like family DNA_pol3_alpha PF07733.12 KFX87444.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain FtsJ PF01728.19 KFX87445.1 - 4.5e-13 49.7 0.0 6.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase adh_short PF00106.25 KFX87446.1 - 2.5e-06 27.1 0.1 2.6e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX87446.1 - 0.0073 16.2 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX87446.1 - 0.027 14.0 0.9 0.042 13.4 0.6 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cutinase PF01083.22 KFX87448.1 - 5.6e-55 186.0 7.3 8e-55 185.6 7.3 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 KFX87448.1 - 2.5e-11 43.3 15.5 2.5e-11 43.3 15.5 3.7 3 1 0 3 3 3 1 Fungal cellulose binding domain PE-PPE PF08237.11 KFX87448.1 - 6.5e-05 22.6 0.2 0.00011 21.9 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 KFX87448.1 - 0.057 12.7 0.6 0.079 12.2 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Toxin_7 PF05980.12 KFX87448.1 - 0.1 12.8 0.6 0.1 12.8 0.6 3.2 2 1 1 3 3 3 0 Toxin 7 Acyl-CoA_dh_1 PF00441.24 KFX87449.1 - 1.1e-29 103.6 0.9 1.5e-29 103.1 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX87449.1 - 3.2e-23 82.5 0.0 8.1e-23 81.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX87449.1 - 7.6e-23 80.5 0.1 1.3e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX87449.1 - 6.4e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.11 KFX87450.1 - 1.4e-09 37.9 13.0 2.3e-09 37.2 13.0 1.3 1 0 0 1 1 1 1 CFEM domain Pex14_N PF04695.13 KFX87450.1 - 0.041 14.5 3.3 0.057 14.1 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Atg29_N PF18388.1 KFX87451.1 - 4.7e-25 87.2 1.6 8.3e-25 86.4 1.6 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain NUDIX PF00293.28 KFX87451.1 - 3.7e-10 40.0 0.0 6.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Yae1_N PF09811.9 KFX87453.1 - 4.7e-12 45.4 1.2 8.2e-12 44.6 1.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Nuclease_act PF08133.11 KFX87453.1 - 0.024 14.8 0.2 0.27 11.5 0.0 2.8 2 0 0 2 2 2 0 Anticodon nuclease activator family Romo1 PF10247.9 KFX87453.1 - 0.12 12.8 0.3 0.24 11.8 0.3 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 rhaM PF05336.13 KFX87454.1 - 6.9e-35 119.4 0.1 1.2e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 L-rhamnose mutarotase Herpes_LMP1 PF05297.11 KFX87454.1 - 0.13 11.5 0.7 0.16 11.2 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Thioredoxin PF00085.20 KFX87455.1 - 7.9e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFX87455.1 - 0.024 15.0 0.0 0.44 10.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Sep15_SelM PF08806.11 KFX87455.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Sep15/SelM redox domain Thioredoxin_2 PF13098.6 KFX87455.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.16 KFX87456.1 - 3.3e-37 128.2 27.2 5.8e-28 97.8 10.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX87456.1 - 2.6e-15 56.2 3.8 2.6e-15 56.2 3.8 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TM140 PF14985.6 KFX87456.1 - 0.036 13.6 0.2 0.093 12.3 0.2 1.6 1 0 0 1 1 1 0 TM140 protein family TRI12 PF06609.13 KFX87456.1 - 0.18 10.2 10.1 0.0094 14.4 4.7 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.19 KFX87457.1 - 8.5e-42 141.4 23.6 4.3e-21 75.0 8.5 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KFX87457.1 - 0.012 15.3 0.3 0.012 15.3 0.3 1.7 2 0 0 2 2 2 0 Integral membrane protein TerC family Myb_DNA-binding PF00249.31 KFX87458.1 - 8.5e-05 22.7 0.4 0.00018 21.6 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX87458.1 - 0.032 14.5 0.1 0.07 13.4 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFX87458.1 - 0.037 14.4 1.2 0.44 11.0 0.1 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KFX87458.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 NOA36 PF06524.12 KFX87462.1 - 5.2 6.3 11.7 6.3 6.0 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein Ish1 PF10281.9 KFX87463.1 - 2.7e-05 24.4 0.2 4.3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KFX87463.1 - 0.017 14.9 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 SAP domain Ribosomal_L38e PF01781.18 KFX87464.1 - 3e-32 110.5 2.7 3.6e-32 110.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family SVIP PF15811.5 KFX87465.1 - 1.1 9.7 6.0 0.26 11.7 2.7 1.7 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DUF1459 PF07312.11 KFX87468.1 - 2.3 8.5 8.8 0.33 11.2 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1459) APH PF01636.23 KFX87469.1 - 8.1e-09 35.8 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 KFX87484.1 - 9e-06 25.5 9.2 9e-06 25.5 9.2 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.18 KFX87485.1 - 6.9e-31 106.0 1.2 4.7e-30 103.3 0.2 2.6 3 0 0 3 3 3 1 SWIB/MDM2 domain DEK_C PF08766.11 KFX87485.1 - 4.8e-14 52.0 0.2 1.2e-13 50.7 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain Ribonuc_2-5A PF06479.12 KFX87486.1 - 7e-44 149.1 0.0 1.6e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KFX87486.1 - 2.3e-42 145.2 0.0 6.1e-40 137.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87486.1 - 2.5e-23 82.7 0.0 2.8e-19 69.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX87486.1 - 0.00042 19.2 0.0 0.00092 18.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PQQ PF01011.21 KFX87486.1 - 0.00072 19.4 2.8 0.0087 16.0 0.1 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 KFX87486.1 - 0.0012 18.5 0.5 0.014 15.0 0.6 2.4 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 KFX87486.1 - 0.0035 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX87486.1 - 0.0085 16.0 0.4 0.043 13.7 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFX87486.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.24 KFX87487.1 - 8.1e-141 470.0 12.6 9.3e-141 469.8 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 KFX87487.1 - 0.087 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) CRM1_repeat PF18777.1 KFX87487.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat eIF2A PF08662.11 KFX87488.1 - 1.2e-34 119.9 2.9 3e-33 115.3 0.3 3.7 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFX87488.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KFX87488.1 - 0.16 12.9 4.5 0.38 11.7 0.0 3.8 6 0 0 6 6 6 0 WD domain, G-beta repeat Far-17a_AIG1 PF04750.14 KFX87489.1 - 6.6e-52 175.8 13.7 7.5e-52 175.6 13.7 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pro_isomerase PF00160.21 KFX87490.1 - 3.2e-51 173.7 0.1 6e-51 172.8 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFX87490.1 - 2.7e-10 40.7 0.0 6.6e-05 23.6 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87490.1 - 0.0044 17.3 0.0 0.032 14.5 0.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX87490.1 - 0.0093 15.0 0.2 0.22 10.5 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_trans_2 PF11951.8 KFX87491.1 - 4.7e-56 190.2 0.4 6.8e-56 189.7 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87491.1 - 5.2e-08 32.9 8.0 9.4e-08 32.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KFX87492.1 - 1e-98 330.8 0.0 1.2e-98 330.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX87492.1 - 5.5e-14 52.9 0.2 1.1e-13 51.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.11 KFX87493.1 - 9.4e-99 330.6 0.0 1.1e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Mito_fiss_reg PF05308.11 KFX87493.1 - 0.21 11.7 3.4 0.29 11.2 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MSA-2c PF12238.8 KFX87493.1 - 0.24 11.4 3.0 0.36 10.8 3.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3437 PF11919.8 KFX87497.1 - 2.2e-30 104.4 0.0 3.6e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KFX87497.1 - 0.073 13.4 4.1 3.5 8.1 0.0 3.1 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KFX87497.1 - 2 9.0 5.7 15 6.2 0.0 3.2 2 2 1 3 3 3 0 HEAT-like repeat Ribosomal_L24e PF01246.20 KFX87499.1 - 2.5e-30 104.5 6.2 2.5e-30 104.5 6.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Pam16 PF03656.13 KFX87500.1 - 4.9e-08 33.0 0.2 7.8e-08 32.4 0.2 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KFX87500.1 - 3.4e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KFX87500.1 - 0.0014 18.2 2.3 0.0014 18.2 2.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) TMP_2 PF06791.13 KFX87500.1 - 0.048 13.3 0.2 0.055 13.1 0.2 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4538 PF15061.6 KFX87500.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) MbtH PF03621.13 KFX87502.1 - 0.066 12.7 0.3 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 MbtH-like protein Ldh_1_C PF02866.18 KFX87504.1 - 1.8e-07 31.2 0.0 2e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TRAPP PF04051.16 KFX87505.1 - 3e-46 156.7 0.0 3.9e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.6 KFX87506.1 - 1.3e-43 148.9 0.1 2.3e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFX87506.1 - 1.3e-21 76.1 5.1 2.4e-21 75.2 5.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFX87506.1 - 6.8e-06 25.8 1.3 1.7e-05 24.5 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KFX87506.1 - 0.019 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger HU-HIG PF18291.1 KFX87506.1 - 0.092 12.8 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif zf-C3HC4_4 PF15227.6 KFX87506.1 - 0.41 10.8 2.5 0.92 9.7 2.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.9 KFX87507.1 - 1.9e-17 63.2 0.3 4.4e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 KFX87507.1 - 3e-13 50.1 2.5 4.5e-08 33.1 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX87507.1 - 3e-05 23.6 0.2 7.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KFX87507.1 - 0.0029 17.0 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 KFX87507.1 - 0.2 10.3 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TRI5 PF06330.11 KFX87508.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) P16-Arc PF04699.14 KFX87511.1 - 5.9e-06 26.8 0.0 7.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Lipase_3 PF01764.25 KFX87514.1 - 7.2e-18 64.8 0.0 6.1e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KFX87514.1 - 0.0021 18.7 1.8 0.005 17.5 1.8 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.25 KFX87515.1 - 1.5e-11 44.6 0.1 2.5e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX87515.1 - 2.4e-09 37.2 0.0 4.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX87515.1 - 5.2e-09 36.4 0.6 1e-08 35.4 0.6 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tetraspanin PF00335.20 KFX87515.1 - 0.00083 19.1 7.6 0.00083 19.1 7.6 1.5 2 0 0 2 2 2 1 Tetraspanin family DUF4191 PF13829.6 KFX87515.1 - 0.55 9.5 0.0 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) zf-RING_2 PF13639.6 KFX87516.1 - 1.1e-11 44.9 2.7 1.6e-11 44.3 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX87516.1 - 3.1e-07 30.3 0.6 6e-07 29.4 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KFX87516.1 - 3.4e-07 30.4 3.1 8.5e-07 29.2 3.1 1.6 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFX87516.1 - 8.2e-07 28.9 1.5 1.2e-06 28.3 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX87516.1 - 2e-06 27.5 3.3 1.5e-05 24.7 3.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX87516.1 - 3e-06 27.0 2.0 0.00012 21.9 0.2 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX87516.1 - 3.1e-06 27.0 2.2 1.2e-05 25.0 2.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX87516.1 - 3.4e-05 23.6 1.0 8.5e-05 22.3 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX87516.1 - 0.0014 18.7 2.7 0.0067 16.6 2.7 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFX87516.1 - 0.012 15.7 2.9 0.035 14.3 2.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KFX87516.1 - 0.013 15.3 0.5 4.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 KFX87516.1 - 0.037 13.6 0.6 0.037 13.6 0.6 1.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KFX87516.1 - 0.037 14.1 1.4 0.093 12.8 1.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 KFX87516.1 - 0.16 12.1 1.6 7.1 6.8 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 KFX87516.1 - 1.6 8.6 7.4 35 4.3 7.9 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Questin_oxidase PF14027.6 KFX87520.1 - 1.4e-90 304.3 1.7 1.8e-90 304.0 1.7 1.1 1 0 0 1 1 1 1 Questin oxidase-like AMP-binding PF00501.28 KFX87522.1 - 2e-62 211.2 0.0 3e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.18 KFX87522.1 - 5.1e-25 88.0 0.1 1.1e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX87522.1 - 1.9e-06 27.9 8.7 5.5e-06 26.4 8.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding_C PF13193.6 KFX87522.1 - 0.0046 17.9 0.0 0.0095 16.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 KFX87523.1 - 3.4e-65 220.0 0.8 5.3e-65 219.3 0.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX87523.1 - 1.4e-44 150.7 0.4 3.2e-44 149.5 0.4 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX87523.1 - 0.0067 16.0 1.9 0.1 12.2 2.1 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFX87523.1 - 0.031 14.1 0.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFX87523.1 - 0.1 12.8 0.4 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MFS_1 PF07690.16 KFX87524.1 - 4.2e-37 127.9 22.4 5.8e-37 127.4 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 KFX87524.1 - 1.2 7.3 8.3 2.1 6.5 8.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Vps26 PF03643.15 KFX87527.1 - 5.2e-128 425.8 0.7 6.1e-128 425.6 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFX87527.1 - 0.00044 20.3 1.6 1.9 8.6 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Fungal_trans_2 PF11951.8 KFX87530.1 - 4.1e-06 25.9 0.0 6.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX87531.1 - 3e-34 118.5 57.8 4e-33 114.8 52.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX87531.1 - 4.8e-06 25.4 0.1 4.8e-06 25.4 0.1 2.7 3 0 0 3 3 3 1 MFS/sugar transport protein LCE PF14672.6 KFX87532.1 - 0.02 15.5 2.0 0.029 14.9 2.0 1.3 1 0 0 1 1 1 0 Late cornified envelope zf-C2H2 PF00096.26 KFX87536.1 - 1.3e-20 72.6 26.0 0.00011 22.5 2.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX87536.1 - 1.9e-18 65.9 28.2 1.8e-06 28.1 1.2 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX87536.1 - 1.9e-11 43.7 26.7 0.005 17.6 1.9 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX87536.1 - 6e-07 29.6 0.4 0.41 11.0 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX87536.1 - 1e-05 25.7 8.9 0.1 13.0 0.0 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type DUF2477 PF10631.9 KFX87536.1 - 0.011 16.4 4.0 0.011 16.4 4.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2477) zf-C2H2_11 PF16622.5 KFX87536.1 - 0.013 15.3 1.8 0.013 15.3 1.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KFX87536.1 - 0.064 13.9 1.8 8.1 7.2 0.2 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 KFX87536.1 - 0.1 12.2 2.5 0.87 9.2 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFX87536.1 - 0.11 12.8 3.8 4.7 7.6 0.0 2.7 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_aberr PF17017.5 KFX87536.1 - 0.96 9.6 2.7 4.5 7.4 0.3 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KFX87536.1 - 1.4 8.9 8.4 2.6 8.1 1.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type IBR PF01485.21 KFX87536.1 - 1.7 8.9 8.9 4.6 7.5 0.6 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-LYAR PF08790.11 KFX87536.1 - 3.6 7.6 5.7 6.5 6.8 0.1 3.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FBPase PF00316.20 KFX87537.1 - 8.6e-71 237.3 0.1 1.2e-70 236.9 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DnaJ PF00226.31 KFX87539.1 - 4e-21 74.9 0.2 1.4e-20 73.2 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain Imm49 PF15575.6 KFX87539.1 - 0.039 13.7 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 49 PBECR1 PF18809.1 KFX87539.1 - 1.1 9.9 6.3 0.27 11.9 0.5 2.6 2 1 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Glyco_hydro81C PF17652.1 KFX87540.1 - 1.1e-160 534.7 6.8 1.4e-160 534.3 6.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KFX87540.1 - 7e-118 393.5 1.2 7e-118 393.5 1.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 KFX87541.1 - 1.4e-209 698.5 65.3 1.4e-209 698.5 65.3 2.1 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 KFX87542.1 - 8.5e-20 70.7 0.4 1.1e-19 70.3 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.25 KFX87543.1 - 5.7e-82 275.6 0.0 9.4e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFX87543.1 - 0.0065 16.2 0.1 0.022 14.5 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.22 KFX87544.1 - 1.4e-81 268.3 3.9 4.6e-22 77.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFX87544.1 - 1.4e-26 92.4 0.4 1.4e-26 92.4 0.4 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KFX87544.1 - 8.3e-10 38.3 0.0 0.044 13.4 0.0 5.2 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX87544.1 - 3.8e-06 26.9 0.5 1.3 9.2 0.0 5.3 5 0 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 KFX87544.1 - 0.00024 21.1 3.4 3 8.0 0.0 4.1 4 0 0 4 4 3 2 Cobalamin biosynthesis central region RRM_occluded PF16842.5 KFX87544.1 - 0.00031 20.5 0.1 0.3 11.0 0.0 3.4 4 0 0 4 4 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFX87544.1 - 0.0027 17.7 1.3 9.8 6.3 0.1 3.7 3 1 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 KFX87544.1 - 0.015 15.0 1.1 7.8 6.3 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KFX87544.1 - 0.031 14.3 0.9 40 4.3 0.0 3.9 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KFX87544.1 - 0.033 13.8 0.1 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated SAPS PF04499.15 KFX87544.1 - 0.089 11.6 6.3 0.15 10.8 6.3 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 KFX87544.1 - 0.77 8.5 8.8 1.2 7.9 8.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Eapp_C PF10238.9 KFX87544.1 - 1.6 8.8 7.0 5.7 7.0 7.0 2.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein CDC45 PF02724.14 KFX87544.1 - 2.2 6.5 18.2 3.1 6.0 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 KFX87544.1 - 2.4 6.6 11.1 3.6 6.1 11.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF913 PF06025.12 KFX87544.1 - 3.4 6.6 8.1 5.9 5.8 8.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KFX87544.1 - 3.6 6.2 10.3 5.4 5.7 10.3 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KFX87544.1 - 4.1 6.5 5.1 6.7 5.8 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TP53IP5 PF15331.6 KFX87544.1 - 4.5 7.4 9.3 9.5 6.3 9.3 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DHHA1 PF02272.19 KFX87544.1 - 5.2 7.5 14.5 6.6 7.1 0.2 3.3 3 1 1 4 4 3 0 DHHA1 domain DNA_pol_phi PF04931.13 KFX87544.1 - 6 4.8 18.6 8.9 4.3 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi SLC12 PF03522.15 KFX87544.1 - 6.6 5.6 9.4 12 4.8 9.4 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF4820 PF16091.5 KFX87544.1 - 7.5 5.8 11.6 15 4.8 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CENP-O PF09496.10 KFX87545.1 - 6.8e-65 219.0 0.0 2.1e-64 217.4 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component ELP6 PF09807.9 KFX87545.1 - 2e-17 63.5 0.0 3.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KFX87545.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Ribosomal_L37e PF01907.19 KFX87546.1 - 7.1e-27 93.3 10.0 1.1e-26 92.8 10.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFX87546.1 - 0.013 15.5 0.9 0.021 14.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFX87546.1 - 0.028 14.4 0.2 0.039 14.0 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 KFX87546.1 - 0.13 12.0 2.7 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 KFX87546.1 - 0.76 9.6 3.5 18 5.2 3.9 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KFX87546.1 - 1.5 8.7 5.3 2.6 8.0 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prefoldin PF02996.17 KFX87547.1 - 0.00058 19.8 12.5 0.00092 19.1 2.1 3.5 2 1 1 3 3 3 1 Prefoldin subunit Fez1 PF06818.15 KFX87547.1 - 0.0028 18.2 9.0 0.0028 18.2 9.0 1.9 2 0 0 2 2 2 1 Fez1 HlyD_2 PF12700.7 KFX87547.1 - 0.015 14.1 0.7 0.022 13.5 0.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein BLOC1_2 PF10046.9 KFX87547.1 - 0.024 14.9 4.4 0.024 14.9 4.4 2.7 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FRQ PF09421.10 KFX87547.1 - 0.088 10.8 1.0 0.11 10.5 1.0 1.1 1 0 0 1 1 1 0 Frequency clock protein HrpB7 PF09486.10 KFX87547.1 - 0.14 12.6 15.0 0.039 14.4 11.3 2.0 2 1 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) DUF3138 PF11336.8 KFX87547.1 - 0.19 10.3 0.5 0.26 9.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MPS2 PF17060.5 KFX87547.1 - 0.25 10.5 6.8 0.15 11.3 4.5 1.7 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF1664 PF07889.12 KFX87547.1 - 0.4 10.7 5.6 2.1 8.4 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFX87547.1 - 0.42 10.6 3.9 0.85 9.7 1.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KFX87547.1 - 0.57 9.7 8.5 1.1 8.8 8.4 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KFX87547.1 - 0.78 9.8 18.1 1 9.4 6.8 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KFX87547.1 - 1.1 9.8 7.3 8.7 6.9 7.0 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 HR1 PF02185.16 KFX87547.1 - 1.1 9.4 14.6 0.32 11.1 2.7 3.3 2 1 1 3 3 3 0 Hr1 repeat DHR10 PF18595.1 KFX87547.1 - 1.5 8.9 17.0 7.3 6.7 14.9 2.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 KFX87547.1 - 1.8 9.1 4.8 3.6 8.1 0.7 3.1 2 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.8 KFX87547.1 - 2.4 7.5 16.9 0.1 12.0 4.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ABC_tran_CTD PF16326.5 KFX87547.1 - 2.6 8.3 22.6 5 7.4 10.1 3.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain SlyX PF04102.12 KFX87547.1 - 2.7 8.7 14.8 9.9 6.9 1.9 3.7 2 1 1 3 3 3 0 SlyX Wtap PF17098.5 KFX87547.1 - 2.8 7.8 12.9 4.2 7.3 11.7 2.3 1 1 0 1 1 1 0 WTAP/Mum2p family MerR-DNA-bind PF09278.11 KFX87547.1 - 3 8.4 14.4 13 6.4 2.7 3.4 2 1 0 2 2 2 0 MerR, DNA binding OmpH PF03938.14 KFX87547.1 - 3.1 8.1 18.9 3.2 8.1 8.0 2.6 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Jnk-SapK_ap_N PF09744.9 KFX87547.1 - 3.4 7.9 20.1 0.33 11.2 4.3 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Laminin_II PF06009.12 KFX87547.1 - 3.5 7.7 11.3 0.99 9.4 2.9 2.7 2 2 2 4 4 2 0 Laminin Domain II Spc7 PF08317.11 KFX87547.1 - 4.6 6.0 19.8 0.56 9.0 7.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 KFX87547.1 - 5.2 7.2 7.8 3.6 7.7 4.0 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4200 PF13863.6 KFX87547.1 - 6.7 7.1 15.6 3.8 7.9 5.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF641 PF04859.12 KFX87547.1 - 7.2 7.0 15.3 13 6.1 1.3 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 KFX87547.1 - 7.8 7.2 16.7 8 7.2 2.2 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fzo_mitofusin PF04799.13 KFX87547.1 - 9.5 5.7 7.7 2.5 7.6 2.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region Presenilin PF01080.17 KFX87548.1 - 3.9 6.1 7.3 4.8 5.8 7.3 1.3 1 0 0 1 1 1 0 Presenilin Septin PF00735.18 KFX87549.1 - 1.9e-32 112.7 0.0 1.1e-10 41.2 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 KFX87549.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 KFX87549.1 - 0.0035 16.6 0.1 0.041 13.1 0.0 2.4 3 0 0 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.23 KFX87549.1 - 0.042 13.9 0.6 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family A_deaminase PF00962.22 KFX87554.1 - 5.5e-23 81.8 0.0 8.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KFX87554.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal SRP40_C PF05022.12 KFX87555.1 - 7.5e-22 78.0 1.1 7.5e-22 78.0 1.1 3.1 3 0 0 3 3 3 1 SRP40, C-terminal domain Sec3_C PF09763.9 KFX87556.1 - 1.9e-212 707.5 6.2 2.5e-212 707.1 6.2 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 p450 PF00067.22 KFX87556.1 - 2e-39 135.7 0.0 6.6e-39 133.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Sec3-PIP2_bind PF15277.6 KFX87556.1 - 1.5e-29 102.0 0.0 3.4e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KFX87556.1 - 0.066 13.6 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DHBP_synthase PF00926.19 KFX87557.1 - 1.9e-78 262.4 0.0 2.2e-78 262.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ParB_C PF18064.1 KFX87557.1 - 0.17 12.1 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Methyltransf_11 PF08241.12 KFX87558.1 - 6.7e-18 65.1 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87558.1 - 6.8e-17 61.8 0.0 1.4e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX87558.1 - 1.8e-14 54.2 0.0 3.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87558.1 - 6e-14 52.5 0.0 1.2e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87558.1 - 4.4e-12 46.0 0.0 6.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFX87558.1 - 4.6e-07 29.1 0.0 6.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KFX87558.1 - 1.9e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX87558.1 - 2.9e-05 23.5 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFX87558.1 - 0.00076 18.9 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 KFX87558.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 KFX87558.1 - 0.037 13.1 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 KFX87558.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CRC_subunit PF08624.10 KFX87560.1 - 1e-51 174.9 0.1 1.5e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.19 KFX87561.1 - 5.8e-99 331.5 0.5 9.6e-99 330.8 0.5 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KFX87561.1 - 6e-31 106.3 0.8 1.5e-30 105.0 0.8 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KFX87561.1 - 2.8e-28 98.5 0.1 6.8e-28 97.2 0.1 1.7 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KFX87561.1 - 7.6e-21 73.9 0.0 2.4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KFX87561.1 - 1.1e-09 38.6 0.1 9.5e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 PIN domain CSD2 PF17876.1 KFX87561.1 - 4.4e-09 36.4 1.4 5.9e-06 26.4 0.0 3.5 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 KFX87561.1 - 0.0032 17.8 0.1 0.013 15.8 0.1 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal TcfC PF16967.5 KFX87561.1 - 0.13 11.8 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 E-set like domain TEBP_beta PF07404.11 KFX87566.1 - 0.082 12.2 0.5 0.1 11.9 0.5 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Zn_clus PF00172.18 KFX87567.1 - 0.00011 22.2 10.4 0.00018 21.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Malic_M PF03949.15 KFX87569.1 - 6.7e-96 320.5 0.0 9.9e-96 319.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFX87569.1 - 5.3e-63 212.1 0.0 8e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GHL10 PF02638.15 KFX87569.1 - 0.0028 16.8 0.1 0.37 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase-like 10 zf-C2H2_4 PF13894.6 KFX87570.1 - 4.1e-07 30.3 2.0 0.0057 17.4 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX87570.1 - 0.00025 21.3 2.7 0.011 16.1 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 KFX87570.1 - 0.26 12.2 1.2 1.1 10.1 0.0 2.2 2 0 0 2 2 2 0 Ima1 N-terminal domain HflK_N PF12221.8 KFX87570.1 - 3.3 7.8 11.1 5.7 7.0 0.1 3.7 3 1 0 3 3 3 0 Bacterial membrane protein N terminal Fcf1 PF04900.12 KFX87575.1 - 2.5e-13 50.2 0.0 4.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Fcf1 SpoIIE PF07228.12 KFX87575.1 - 0.00024 21.1 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFX87575.1 - 0.00042 20.0 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Transposase_24 PF03004.14 KFX87575.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) FA_hydroxylase PF04116.13 KFX87584.1 - 2.8e-26 92.4 16.9 2.8e-26 92.4 16.9 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily IMPDH PF00478.25 KFX87587.1 - 1e-124 416.0 6.7 1.2e-124 415.8 6.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFX87587.1 - 1.5e-15 57.4 0.0 1.7e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KFX87587.1 - 2.6e-09 36.9 4.7 0.00034 20.1 0.0 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KFX87587.1 - 1.2e-06 27.9 0.8 8e-06 25.1 0.3 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase YpsA PF06908.11 KFX87587.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family His_biosynth PF00977.21 KFX87587.1 - 0.024 14.1 2.1 0.67 9.4 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KFX87587.1 - 0.041 13.1 0.2 0.08 12.1 0.2 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 KFX87587.1 - 0.06 12.2 0.0 0.18 10.7 0.0 1.7 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Choline_kin_N PF04428.14 KFX87587.1 - 0.18 11.5 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Choline kinase N terminus WD40 PF00400.32 KFX87592.1 - 7e-17 61.5 5.4 0.0022 18.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87592.1 - 2.1e-06 27.9 0.0 0.0031 17.8 0.0 4.4 3 3 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX87592.1 - 0.00081 18.2 0.0 0.0072 15.0 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFX87592.1 - 0.00082 18.8 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KFX87592.1 - 0.15 11.0 0.2 0.52 9.2 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Y_phosphatase2 PF03162.13 KFX87593.1 - 4.4e-47 159.7 0.0 6e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KFX87593.1 - 4.8e-10 39.8 0.0 1.5e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX87593.1 - 0.0048 16.5 0.1 0.0074 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX87593.1 - 0.026 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aim19 PF10315.9 KFX87594.1 - 2.1e-05 24.8 0.8 2.8e-05 24.4 0.8 1.4 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 KFX87595.1 - 2.7e-29 101.5 0.2 5.1e-29 100.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFX87595.1 - 8.1e-19 67.5 0.1 1.5e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Ufd2P_core PF10408.9 KFX87596.1 - 9.6e-210 698.4 11.6 1.2e-209 698.1 11.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFX87596.1 - 1e-20 73.6 0.8 3.3e-20 72.0 0.8 2.0 1 0 0 1 1 1 1 U-box domain Syntaxin_2 PF14523.6 KFX87597.1 - 7.6e-28 96.8 8.9 1.1e-27 96.3 2.8 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KFX87597.1 - 2.4e-17 62.6 0.9 7.8e-17 61.0 0.6 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KFX87597.1 - 3.3e-05 23.7 10.3 0.00023 20.9 10.3 2.3 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 KFX87597.1 - 0.0016 18.2 0.2 0.04 13.7 0.1 2.6 2 0 0 2 2 2 1 Synaptobrevin Nre_C PF04895.12 KFX87597.1 - 0.0019 18.1 0.9 0.0069 16.3 0.2 2.2 2 0 0 2 2 2 1 Archaeal Nre, C-terminal Dala_Dala_lig_C PF07478.13 KFX87597.1 - 0.018 14.6 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus K_channel_TID PF07941.11 KFX87597.1 - 0.024 15.1 3.8 0.051 14.0 3.8 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain MCPsignal PF00015.21 KFX87597.1 - 0.029 14.2 5.5 0.29 10.9 1.1 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF883 PF05957.13 KFX87597.1 - 0.09 13.4 11.5 1.3 9.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF948 PF06103.11 KFX87597.1 - 0.12 12.7 3.2 3.7 7.9 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 KFX87597.1 - 0.37 8.7 4.3 1.3 6.9 4.3 1.9 1 1 0 1 1 1 0 Prominin ISG65-75 PF11727.8 KFX87597.1 - 0.39 9.9 4.8 0.15 11.2 0.7 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2116 PF09889.9 KFX87597.1 - 0.41 10.7 1.1 0.89 9.6 1.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF16 PF01519.16 KFX87597.1 - 0.61 10.6 9.5 0.15 12.5 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 T3SSipB PF16535.5 KFX87597.1 - 2.4 8.6 10.8 1.9 9.0 6.7 2.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4407 PF14362.6 KFX87597.1 - 3.1 7.1 12.7 6.1 6.1 12.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 KFX87597.1 - 3.3 8.3 10.3 5.6 7.6 0.2 3.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ndc1_Nup PF09531.10 KFX87598.1 - 5e-195 649.7 0.0 5.7e-195 649.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DSPc PF00782.20 KFX87599.1 - 4.3e-24 84.8 0.0 6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFX87599.1 - 2.8e-05 24.4 0.0 4.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KFX87599.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFX87599.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Gly_transf_sug PF04488.15 KFX87602.1 - 1e-08 35.7 0.0 2.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFX87602.1 - 0.023 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Pectate_lyase_3 PF12708.7 KFX87604.1 - 1.7e-74 250.3 7.5 3.5e-66 223.1 0.1 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 KFX87604.1 - 8.6e-16 58.0 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Proteasome PF00227.26 KFX87611.1 - 1.2e-45 155.3 0.1 1.6e-31 109.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFX87611.1 - 2e-11 43.3 0.0 4.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PknG_rubred PF16919.5 KFX87612.1 - 0.025 14.7 23.5 1.2 9.3 2.5 5.8 2 2 4 6 6 6 0 Protein kinase G rubredoxin domain Iso_dh PF00180.20 KFX87613.1 - 8.5e-84 281.7 0.0 1e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ABC_membrane PF00664.23 KFX87616.1 - 1.8e-87 293.5 26.2 6.3e-49 167.1 5.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX87616.1 - 1.7e-63 213.2 0.1 4.4e-34 117.9 0.1 3.2 2 1 0 2 2 2 2 ABC transporter Exo_endo_phos PF03372.23 KFX87616.1 - 4e-19 69.1 0.1 1.2e-18 67.6 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.19 KFX87616.1 - 5.6e-15 55.4 2.7 0.00019 20.9 0.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain LRR_8 PF13855.6 KFX87616.1 - 1e-09 38.0 3.2 3.3e-06 26.8 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat AAA_22 PF13401.6 KFX87616.1 - 1.5e-08 35.0 0.3 0.01 16.1 0.0 3.7 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KFX87616.1 - 3.1e-08 34.2 0.7 0.0016 18.8 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX87616.1 - 1.2e-07 31.8 0.0 0.0072 16.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFX87616.1 - 1.6e-07 30.9 1.3 0.011 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX87616.1 - 1.1e-06 28.5 0.4 0.02 14.6 0.0 3.1 3 1 0 3 3 2 2 AAA domain LRR_4 PF12799.7 KFX87616.1 - 1.9e-06 28.1 4.7 0.0014 19.0 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_23 PF13476.6 KFX87616.1 - 2.3e-06 28.2 0.0 0.019 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFX87616.1 - 2.5e-06 27.4 0.0 0.06 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KFX87616.1 - 2.7e-06 26.4 2.8 0.014 14.3 0.0 4.8 5 0 0 5 5 5 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KFX87616.1 - 2.1e-05 24.5 0.0 0.17 11.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFX87616.1 - 9.7e-05 22.4 0.0 0.054 13.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KFX87616.1 - 0.00018 21.1 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 KFX87616.1 - 0.0003 21.3 0.1 1.3 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KFX87616.1 - 0.00051 20.5 2.0 0.26 11.7 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFX87616.1 - 0.00051 20.5 0.2 0.11 13.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX87616.1 - 0.00086 18.9 2.8 0.64 9.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.14 KFX87616.1 - 0.001 19.0 0.1 1.2 9.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFX87616.1 - 0.0012 18.2 0.0 0.066 12.5 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 KFX87616.1 - 0.0043 17.2 0.4 4.8 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KFX87616.1 - 0.0061 16.3 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KFX87616.1 - 0.01 16.1 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX87616.1 - 0.019 14.7 0.1 5.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KFX87616.1 - 0.021 14.6 0.1 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KFX87616.1 - 0.024 14.9 0.8 5.7 7.2 0.1 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.25 KFX87616.1 - 0.024 14.3 0.4 4.1 7.0 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KFX87616.1 - 0.025 14.6 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 KFX87616.1 - 0.033 14.3 0.8 2.5 8.1 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 KFX87616.1 - 0.038 13.7 0.1 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 KFX87616.1 - 0.047 14.1 0.1 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFX87616.1 - 0.05 12.8 0.2 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KFX87616.1 - 0.083 13.0 0.0 7.3 6.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 KFX87616.1 - 0.09 12.7 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase SRP54 PF00448.22 KFX87616.1 - 0.1 12.2 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KFX87616.1 - 0.13 12.0 0.1 9.6 5.9 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein G-alpha PF00503.20 KFX87616.1 - 0.22 10.6 0.9 6 5.9 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit LRR_1 PF00560.33 KFX87616.1 - 1.7 9.5 5.6 16 6.5 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat Erythro_esteras PF05139.14 KFX87617.1 - 2.6e-120 402.4 2.0 3e-120 402.1 2.0 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF1416 PF07210.12 KFX87617.1 - 0.15 11.9 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) Glyco_hydro_56 PF01630.18 KFX87617.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase FAD_binding_4 PF01565.23 KFX87618.1 - 1e-16 60.9 0.1 1.6e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ArsB PF02040.15 KFX87619.1 - 5.7e-10 39.1 23.1 1.1e-05 25.0 9.5 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein SurA_N_3 PF13624.6 KFX87619.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 SurA N-terminal domain ADH_zinc_N PF00107.26 KFX87621.1 - 1.6e-22 79.9 0.1 2.8e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX87621.1 - 2.1e-15 58.0 0.0 1.2e-14 55.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX87621.1 - 0.00044 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KFX87621.1 - 0.073 12.4 0.3 0.27 10.5 0.0 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CbiG_N PF11760.8 KFX87621.1 - 0.12 12.4 0.2 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal GFO_IDH_MocA PF01408.22 KFX87622.1 - 2.2e-18 67.2 1.0 3.6e-18 66.5 1.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 KFX87622.1 - 0.049 14.3 0.8 0.17 12.6 0.3 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GARS_N PF02844.15 KFX87622.1 - 0.082 13.7 0.1 0.23 12.2 0.1 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NAD_binding_3 PF03447.16 KFX87622.1 - 0.097 13.3 1.3 0.19 12.4 1.3 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KFX87622.1 - 0.098 13.1 0.3 0.19 12.2 0.3 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 KFX87624.1 - 5.1e-81 272.0 0.0 8.9e-81 271.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFX87624.1 - 1.1e-44 152.9 7.6 1.3e-43 149.5 0.3 4.2 4 0 0 4 4 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFX87624.1 - 2.2e-38 132.6 0.1 3.9e-38 131.8 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX87624.1 - 2.6e-32 111.3 0.2 6e-32 110.1 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFX87624.1 - 7.6e-22 77.7 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KFX87624.1 - 5e-20 71.6 8.7 1.6e-10 41.2 1.9 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KFX87624.1 - 4.7e-11 42.5 0.0 7.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KFX87624.1 - 3e-05 23.5 0.0 7.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFX87624.1 - 0.00041 20.8 0.0 0.0012 19.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension RmlD_sub_bind PF04321.17 KFX87624.1 - 0.00042 19.5 0.0 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFX87624.1 - 0.003 16.8 0.0 0.027 13.6 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX87624.1 - 0.02 14.3 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SnoaL_4 PF13577.6 KFX87625.1 - 4e-22 78.7 0.2 4.5e-22 78.5 0.2 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KFX87625.1 - 0.028 15.0 0.0 0.037 14.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Lumazine_bd_2 PF12893.7 KFX87625.1 - 0.064 13.9 0.1 0.099 13.3 0.1 1.3 1 0 0 1 1 1 0 Putative lumazine-binding Lin-8 PF03353.15 KFX87625.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ADH_N PF08240.12 KFX87626.1 - 1.8e-10 40.6 0.0 1.4e-09 37.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX87626.1 - 1e-06 28.7 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX87626.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Methyltransf_2 PF00891.18 KFX87627.1 - 8e-12 44.9 0.1 3e-11 43.0 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KFX87627.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Transferase PF02458.15 KFX87628.1 - 0.00079 18.2 0.0 0.0053 15.5 0.0 2.0 1 1 0 1 1 1 1 Transferase family DUF2064 PF09837.9 KFX87628.1 - 0.059 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_hydro_3 PF00933.21 KFX87629.1 - 6e-51 173.7 0.0 7.6e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1343 PF07075.11 KFX87630.1 - 2.3e-118 395.6 0.0 2.6e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) MFS_1 PF07690.16 KFX87631.1 - 2.2e-31 109.1 26.2 2.2e-31 109.1 26.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX87631.1 - 0.00011 21.6 1.3 0.00011 21.6 1.3 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 KFX87631.1 - 0.085 12.5 0.1 0.085 12.5 0.1 3.3 3 2 2 5 5 5 0 Domain of unknown function (DUF4131) AnmK PF03702.14 KFX87632.1 - 1.8e-74 251.0 0.0 2.1e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase MLANA PF14991.6 KFX87637.1 - 0.093 13.0 0.3 0.093 13.0 0.3 1.7 2 0 0 2 2 2 0 Protein melan-A NUDE_C PF04880.13 KFX87639.1 - 5 7.6 8.9 13 6.2 8.9 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DivIC PF04977.15 KFX87640.1 - 0.31 10.8 6.3 4.8 7.0 0.2 2.8 2 1 0 2 2 2 0 Septum formation initiator Radial_spoke_3 PF06098.11 KFX87640.1 - 2.6 7.2 15.9 0.092 12.0 6.1 2.5 2 0 0 2 2 2 0 Radial spoke protein 3 Spc7 PF08317.11 KFX87640.1 - 9.3 5.0 18.5 3.3 6.5 6.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein 4HBT_2 PF13279.6 KFX87641.1 - 2e-24 86.4 0.0 4.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KFX87641.1 - 0.026 14.9 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily DUF349 PF03993.12 KFX87641.1 - 0.31 11.4 0.0 0.31 11.4 0.0 2.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Complex1_LYR_2 PF13233.6 KFX87642.1 - 5.1e-05 23.9 0.0 6.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFX87642.1 - 0.00046 20.2 0.0 0.0006 19.8 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 KFX87643.1 - 2.4e-15 57.0 0.0 5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX87643.1 - 3.2e-11 43.7 0.0 6.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87643.1 - 9.3e-10 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87643.1 - 4e-07 30.0 0.0 7.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX87643.1 - 3.9e-06 27.5 0.0 8.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFX87643.1 - 0.0035 17.3 0.1 0.0098 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX87643.1 - 0.0047 16.5 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KFX87643.1 - 0.0057 17.7 0.0 0.016 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFX87643.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KFX87643.1 - 0.0072 16.1 0.0 0.028 14.2 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KFX87643.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4366 PF14283.6 KFX87649.1 - 1.6 8.8 3.7 4.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) VHS PF00790.19 KFX87650.1 - 7.2e-24 84.2 0.0 1.8e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KFX87650.1 - 4e-06 27.0 1.5 1.1e-05 25.6 1.5 1.8 1 0 0 1 1 1 1 GAT domain ARID PF01388.21 KFX87651.1 - 1.2e-18 67.6 0.0 3.9e-11 43.5 0.1 2.7 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain Myb_DNA-bind_2 PF08914.11 KFX87651.1 - 2.5e-16 59.6 0.6 9.1e-16 57.8 0.1 2.3 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KFX87651.1 - 9.9e-15 54.4 0.4 2.4e-14 53.2 0.4 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 KFX87651.1 - 8e-06 26.2 0.0 3.5e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KFX87651.1 - 0.0036 17.9 0.0 0.0036 17.9 0.0 3.1 4 0 0 4 4 4 1 Rap1, DNA-binding Prp18 PF02840.15 KFX87651.1 - 0.12 12.5 0.6 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 Prp18 domain DHHC PF01529.20 KFX87652.1 - 2.4e-31 108.6 4.6 2.4e-31 108.6 4.6 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF1418 PF07214.12 KFX87652.1 - 0.021 14.7 2.7 0.054 13.3 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Flavoprotein PF02441.19 KFX87653.1 - 4.1e-19 68.9 0.0 6.8e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DUF21 PF01595.20 KFX87654.1 - 1.3e-28 99.9 0.0 2.6e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFX87654.1 - 1.1e-06 28.9 0.2 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Fibrinogen_aC PF12160.8 KFX87654.1 - 0.018 14.9 0.4 0.051 13.4 0.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha C domain Chromo_shadow PF01393.19 KFX87656.1 - 1.7e-15 56.9 1.0 1.3e-13 50.8 0.5 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFX87656.1 - 4.6e-11 42.4 0.3 4.6e-11 42.4 0.3 2.1 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Myc_N PF01056.18 KFX87656.1 - 0.21 11.4 10.1 0.12 12.3 5.8 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DUF4217 PF13959.6 KFX87658.1 - 0.008 16.4 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) YlmH_RBD PF17774.1 KFX87659.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Pkinase PF00069.25 KFX87662.1 - 1.3e-71 241.0 0.0 2.4e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87662.1 - 1.8e-44 152.0 0.0 3.2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFX87662.1 - 7e-22 77.5 0.1 2.3e-21 75.9 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KFX87662.1 - 7.8e-08 31.5 2.5 5.9e-07 28.6 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFX87662.1 - 2.1e-07 30.6 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFX87662.1 - 0.037 13.4 0.1 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX87662.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFX87662.1 - 0.36 10.4 1.7 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TFIIA PF03153.13 KFX87662.1 - 1.1 9.2 32.9 0.012 15.6 20.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFX87662.1 - 4 5.6 19.9 6.9 4.8 19.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AsmA PF05170.14 KFX87663.1 - 0.12 11.2 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 AsmA family DUF3759 PF12585.8 KFX87663.1 - 0.19 11.8 0.1 0.27 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) DEAD PF00270.29 KFX87667.1 - 3.3e-28 98.6 0.1 7.3e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX87667.1 - 1.9e-25 89.4 0.1 5.2e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX87667.1 - 0.00022 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M10_C PF08548.11 KFX87667.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Peptidase M10 serralysin C terminal Anp1 PF03452.14 KFX87670.1 - 9.1e-106 353.1 0.0 1.1e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFX87670.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Band_7 PF01145.25 KFX87673.1 - 1.9e-24 86.6 6.9 3.9e-24 85.6 6.9 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KFX87673.1 - 0.00019 20.6 4.0 0.00025 20.2 4.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.16 KFX87674.1 - 3.7e-36 122.9 0.5 4.3e-36 122.7 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Nucleopor_Nup85 PF07575.13 KFX87675.1 - 8e-20 70.9 0.2 5.4e-13 48.4 0.0 3.1 3 0 0 3 3 3 3 Nup85 Nucleoporin DUF2282 PF10048.9 KFX87679.1 - 0.16 12.0 7.8 0.67 10.0 1.0 2.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2282) Ctr PF04145.15 KFX87680.1 - 1.4e-30 106.9 0.1 1.6e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Malate_synthase PF01274.22 KFX87681.1 - 9.3e-230 763.3 0.0 1.1e-229 763.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Rpr2 PF04032.16 KFX87682.1 - 1.3e-25 89.5 0.3 2.5e-25 88.6 0.3 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 KFX87683.1 - 1.4e-37 129.1 0.2 2.4e-37 128.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX87683.1 - 3.6e-26 91.7 0.3 2.2e-23 82.7 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KFX87683.1 - 3e-10 40.3 0.1 6.4e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KRE1 PF17056.5 KFX87689.1 - 3.9e-10 39.3 0.4 5.2e-10 38.9 0.4 1.1 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 UDG PF03167.19 KFX87694.1 - 2.5e-07 30.8 0.0 5.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MARVEL PF01284.23 KFX87694.1 - 0.0008 19.5 9.4 0.0034 17.4 9.6 1.9 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 KFX87694.1 - 5.6 6.5 9.6 0.17 11.4 3.0 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Isochorismatase PF00857.20 KFX87695.1 - 6.1e-29 101.4 0.0 1.9e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.32 KFX87696.1 - 0.16 12.9 5.2 6.2 7.9 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat UDG PF03167.19 KFX87697.1 - 2.6e-07 30.8 0.0 6.4e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily MRI PF15325.6 KFX87697.1 - 0.024 15.7 0.0 0.047 14.8 0.0 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Nup188_C PF18378.1 KFX87698.1 - 1.1e-122 409.5 0.1 1.8e-122 408.8 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KFX87698.1 - 1.4e-78 264.9 0.0 2e-77 261.0 0.0 2.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF1754 PF08555.10 KFX87698.1 - 1.9e-11 44.6 10.3 4e-11 43.6 10.3 1.6 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) IGPS PF00218.21 KFX87699.1 - 7.9e-93 310.3 0.0 1.2e-92 309.7 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KFX87699.1 - 6.8e-53 179.3 0.7 5.4e-49 166.6 0.1 3.0 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KFX87699.1 - 7.9e-47 159.5 0.0 1.3e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFX87699.1 - 0.00056 19.7 0.8 0.0019 18.0 0.3 2.2 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 KFX87699.1 - 0.0088 15.8 0.9 0.29 10.9 0.1 2.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KFX87699.1 - 0.045 13.2 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KFX87699.1 - 0.056 12.6 0.1 0.33 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_2 PF01497.18 KFX87699.1 - 0.091 12.3 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein BRCT PF00533.26 KFX87700.1 - 4.1e-08 33.5 0.0 7.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFX87700.1 - 6.6e-05 23.3 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Nop16 PF09420.10 KFX87700.1 - 0.008 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Na_trans_assoc PF06512.13 KFX87700.1 - 0.19 12.0 0.3 0.35 11.1 0.3 1.4 1 1 0 1 1 1 0 Sodium ion transport-associated IPK PF03770.16 KFX87704.1 - 2.3e-53 181.0 0.0 2.8e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 KFX87705.1 - 4.2e-138 460.9 0.0 5.2e-138 460.6 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 NAGidase PF07555.13 KFX87706.1 - 7.5e-97 324.2 0.2 1.3e-96 323.4 0.2 1.4 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 KFX87706.1 - 3.8e-19 69.7 0.1 7.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 KFX87706.1 - 0.00035 20.8 0.1 0.0008 19.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus THDPS_N_2 PF14805.6 KFX87706.1 - 0.1 12.8 1.4 5.8 7.2 0.4 2.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal TPR_12 PF13424.6 KFX87707.1 - 5.1e-21 74.7 11.0 2.7e-08 34.0 0.1 6.4 6 1 1 7 7 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 KFX87707.1 - 5.1e-18 65.2 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KFX87707.1 - 2.6e-14 52.6 7.4 0.0028 17.5 0.2 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX87707.1 - 2.5e-09 36.6 9.1 0.019 15.1 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX87707.1 - 2.6e-07 30.2 7.9 1.9 8.8 0.1 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX87707.1 - 1.1e-06 28.2 0.7 0.0013 18.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX87707.1 - 1.3e-06 28.1 0.3 0.05 13.0 0.0 3.0 2 1 1 3 3 3 2 MalT-like TPR region AAA_16 PF13191.6 KFX87707.1 - 1.7e-05 25.3 0.6 8.2e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.6 KFX87707.1 - 1.8e-05 24.4 5.2 0.19 11.8 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX87707.1 - 0.00014 22.4 1.3 0.48 11.1 0.4 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX87707.1 - 0.00049 20.7 11.5 0.55 11.2 0.3 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat Goodbye PF17109.5 KFX87707.1 - 0.00076 19.9 0.0 0.0049 17.3 0.0 2.5 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain PPR PF01535.20 KFX87707.1 - 0.00077 19.6 2.4 1.4 9.3 0.0 4.3 4 0 0 4 4 4 1 PPR repeat ANAPC3 PF12895.7 KFX87707.1 - 0.0032 17.6 1.3 0.22 11.8 0.2 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFX87707.1 - 0.0041 17.6 10.7 0.15 12.6 2.1 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX87707.1 - 0.0062 16.2 0.4 4.4 7.1 0.0 3.6 3 0 0 3 3 3 1 TPR repeat AAA_22 PF13401.6 KFX87707.1 - 0.012 15.9 0.0 0.061 13.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain TPR_6 PF13174.6 KFX87707.1 - 0.081 13.6 3.4 48 4.9 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX87707.1 - 0.13 12.9 0.8 9.2 7.2 0.1 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Peptidase_M49 PF03571.15 KFX87709.1 - 7.9e-211 701.2 0.0 1e-210 700.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KFX87709.1 - 0.089 13.0 0.5 1.2 9.4 0.3 2.4 2 0 0 2 2 2 0 2-cysteine adaptor domain APH PF01636.23 KFX87710.1 - 0.00011 22.3 0.5 0.00041 20.4 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Beta-lactamase PF00144.24 KFX87711.1 - 9.3e-31 107.3 0.9 2.3e-30 106.0 0.9 1.5 1 1 0 1 1 1 1 Beta-lactamase Melibiase_2 PF16499.5 KFX87712.1 - 9.3e-61 205.5 3.6 1.7e-60 204.6 3.6 1.4 1 1 0 1 1 1 1 Alpha galactosidase A CBM_1 PF00734.18 KFX87712.1 - 1.8e-11 43.8 15.6 1.8e-11 43.8 15.6 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Melibiase_C PF17801.1 KFX87712.1 - 3.4e-11 43.0 0.8 1.4e-08 34.7 0.0 2.9 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX87712.1 - 1e-05 24.7 0.0 2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Melibiase Glyco_hydro_30C PF17189.4 KFX87713.1 - 5.7e-09 36.1 9.9 2.7e-08 33.9 9.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFX87713.1 - 0.00093 18.5 0.0 0.055 12.7 0.0 2.6 1 1 2 3 3 3 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KFX87713.1 - 0.0086 15.7 0.0 0.047 13.3 0.0 2.0 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 PDZ_assoc PF10600.9 KFX87713.1 - 0.49 11.3 2.0 53 4.7 0.7 2.7 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors ArabFuran-catal PF09206.11 KFX87714.1 - 2e-150 500.5 13.9 2.6e-150 500.1 13.9 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBM_1 PF00734.18 KFX87714.1 - 1.8e-10 40.6 18.0 1.8e-10 40.6 18.0 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_39 PF01229.17 KFX87715.1 - 0.0015 17.2 0.1 0.0021 16.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 CBM_1 PF00734.18 KFX87715.1 - 0.83 9.7 15.7 2.1 8.4 15.7 1.7 1 0 0 1 1 1 0 Fungal cellulose binding domain Sulfatase PF00884.23 KFX87716.1 - 3.1e-45 154.9 0.8 2.8e-43 148.5 0.0 2.4 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KFX87716.1 - 5.6e-06 26.5 3.3 0.00022 21.4 0.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFX87716.1 - 0.0038 16.9 0.0 0.039 13.5 0.0 2.1 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFX87716.1 - 0.0076 14.9 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 KFX87716.1 - 0.022 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Thioredox_DsbH PF03190.15 KFX87716.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Sulfatase_C PF14707.6 KFX87716.1 - 0.093 13.5 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase MFS_1 PF07690.16 KFX87717.1 - 1.8e-19 69.9 20.2 2.2e-19 69.6 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KFX87717.1 - 0.015 15.6 0.3 0.3 11.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4500 PF14937.6 KFX87717.1 - 0.046 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF2417 PF10329.9 KFX87717.1 - 1.3 8.4 7.3 1.6 8.1 2.9 2.8 3 0 0 3 3 3 0 Region of unknown function (DUF2417) MatE PF01554.18 KFX87718.1 - 9.3e-59 197.7 28.1 8.9e-33 113.2 9.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFX87718.1 - 0.0006 19.9 8.5 0.0006 19.9 8.5 3.7 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.15 KFX87719.1 - 1.3e-16 60.8 1.3 8.2e-16 58.2 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 KFX87719.1 - 0.036 14.2 1.8 0.58 10.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Fibrillarin_2 PF10113.9 KFX87719.1 - 0.073 11.7 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein DUF5336 PF17270.2 KFX87719.1 - 0.13 11.9 0.5 0.18 11.4 0.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5336) Oxidored_q3 PF00499.20 KFX87719.1 - 0.14 11.9 3.5 0.77 9.5 3.7 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Autophagy_N PF03986.13 KFX87721.1 - 7.1e-25 87.5 0.7 1.2e-24 86.8 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KFX87721.1 - 1.8e-14 52.9 0.4 3.1e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KFX87721.1 - 5.3e-12 46.1 0.0 9.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain PAH PF02671.21 KFX87722.1 - 3.7e-07 30.2 2.9 0.0032 17.6 0.3 3.0 3 1 0 3 3 3 2 Paired amphipathic helix repeat Ribonuc_L-PSP PF01042.21 KFX87722.1 - 0.094 12.7 0.1 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 Endoribonuclease L-PSP Pec_lyase_C PF00544.19 KFX87724.1 - 8.1e-45 153.0 1.3 1.2e-44 152.5 1.3 1.2 1 0 0 1 1 1 1 Pectate lyase Sulfotransfer_3 PF13469.6 KFX87725.1 - 4.6e-06 27.2 0.0 6.5e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family DUF4400 PF14348.6 KFX87725.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) NmrA PF05368.13 KFX87733.1 - 4.7e-60 203.0 0.7 6e-60 202.7 0.7 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX87733.1 - 4.9e-18 65.7 0.6 7.4e-18 65.1 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX87733.1 - 3.9e-07 29.4 0.2 5.5e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KFX87733.1 - 0.0089 16.3 0.2 0.016 15.5 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PUL PF08324.11 KFX87734.1 - 1.2e-64 218.2 0.4 1.7e-64 217.7 0.4 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFX87734.1 - 2.7e-43 146.8 0.5 5.8e-43 145.7 0.5 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFX87734.1 - 1.8e-33 114.0 3.7 6.6e-06 26.8 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KFX87734.1 - 0.031 13.6 0.0 0.079 12.3 0.0 1.8 1 1 0 1 1 1 0 WD40-like domain Peptidase_M23 PF01551.22 KFX87734.1 - 0.11 12.7 0.6 5 7.4 0.3 2.9 2 0 0 2 2 2 0 Peptidase family M23 WD40 PF00400.32 KFX87735.1 - 6.2e-28 96.5 5.5 7.3e-09 36.1 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87735.1 - 1e-10 41.7 0.0 0.021 15.1 0.0 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX87735.1 - 0.00032 19.8 0.0 0.055 12.4 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX87735.1 - 0.012 14.3 0.1 0.37 9.4 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Fe-S_biosyn PF01521.20 KFX87742.1 - 5e-20 71.7 0.0 7.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CPT_N PF16484.5 KFX87742.1 - 0.023 14.7 0.3 0.077 13.0 0.0 1.9 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus IFRD PF05004.13 KFX87743.1 - 0.025 13.7 0.1 0.045 12.8 0.1 1.5 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF1365 PF07103.11 KFX87752.1 - 3.2e-36 125.2 0.0 4.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) McyA_C PF12593.8 KFX87752.1 - 0.11 12.3 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 Microcystin synthetase C terminal CP12 PF02672.15 KFX87753.1 - 0.074 13.8 2.2 0.13 13.0 2.0 1.5 1 1 0 1 1 1 0 CP12 domain FCP1_C PF09309.10 KFX87753.1 - 0.16 11.8 7.0 0.2 11.5 7.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal SseB_C PF14581.6 KFX87754.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 SseB protein C-terminal domain Pyr_redox_3 PF13738.6 KFX87756.1 - 2.9e-14 53.0 0.1 1.3e-11 44.3 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX87756.1 - 6.6e-14 51.2 0.2 5.3e-13 48.2 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX87756.1 - 6.9e-12 45.2 0.1 8e-09 35.1 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFX87756.1 - 7.3e-11 41.8 0.0 3e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX87756.1 - 6.3e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX87756.1 - 0.00015 21.8 0.0 0.06 13.3 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFX87756.1 - 0.00017 21.3 0.4 0.01 15.4 0.0 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFX87756.1 - 0.0012 18.9 0.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFX87756.1 - 0.06 12.4 0.0 1.3 8.0 0.0 2.1 1 1 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KFX87756.1 - 0.061 13.9 0.0 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX87756.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KFX87756.1 - 0.15 10.8 0.0 11 4.6 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein FSH1 PF03959.13 KFX87757.1 - 1.1e-54 185.3 0.0 1.4e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) RT_RNaseH_2 PF17919.1 KFX87757.1 - 3.5e-29 100.8 0.1 6.6e-29 99.9 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KFX87757.1 - 4.9e-24 84.6 0.0 8.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Abhydrolase_6 PF12697.7 KFX87757.1 - 0.0019 18.9 0.0 0.0051 17.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX87757.1 - 0.016 14.5 0.0 0.19 11.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFX87757.1 - 0.039 13.7 1.6 35 4.1 0.0 3.5 4 0 0 4 4 4 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KFX87757.1 - 0.045 13.8 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KFX87757.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 KFX87757.1 - 0.13 11.8 0.0 19 4.7 0.0 2.5 2 0 0 2 2 2 0 Dienelactone hydrolase family FSA_C PF10479.9 KFX87759.1 - 4.3 5.4 6.4 5.9 4.9 6.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DinB PF05163.12 KFX87764.1 - 0.0021 18.0 0.5 0.0021 18.0 0.5 1.7 2 0 0 2 2 2 1 DinB family DUF4798 PF16055.5 KFX87764.1 - 0.37 11.0 3.8 0.72 10.1 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Nop14 PF04147.12 KFX87765.1 - 0.39 8.9 29.9 0.48 8.6 29.9 1.1 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.13 KFX87765.1 - 0.49 9.6 7.0 0.63 9.2 7.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2151 PF10221.9 KFX87765.1 - 1.3 7.6 8.1 1.3 7.5 8.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SDA1 PF05285.12 KFX87765.1 - 3.8 6.8 31.5 4.5 6.6 31.5 1.1 1 0 0 1 1 1 0 SDA1 HlyD PF00529.20 KFX87768.1 - 0.1 12.5 0.2 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS TctA PF01970.16 KFX87771.1 - 0.4 9.3 0.7 0.59 8.8 0.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family zf-C3HC4_3 PF13920.6 KFX87771.1 - 1.8 8.5 6.6 5.1 7.1 2.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAGA_bind PF06217.12 KFX87771.1 - 1.8 8.8 7.2 0.41 10.9 2.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 KFX87771.1 - 2.2 8.3 18.5 1.6 8.8 11.6 2.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 O-antigen_lig PF13425.6 KFX87771.1 - 6.6 5.4 5.3 9.3 4.9 5.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RRM_1 PF00076.22 KFX87772.1 - 1.7e-08 34.1 0.1 3.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX87772.1 - 7.7e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFX87772.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFX87772.1 - 0.054 13.5 0.3 0.15 12.1 0.3 1.8 1 0 0 1 1 1 0 RNA binding motif O-FucT PF10250.9 KFX87776.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Dicty_CAR PF05462.11 KFX87777.1 - 1e-16 61.0 5.6 1e-16 61.0 5.6 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KFX87777.1 - 6e-08 32.3 5.0 1.2e-07 31.3 5.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KFX87777.1 - 2.7e-07 30.6 11.5 5.2e-07 29.7 11.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KFX87777.1 - 8.4e-05 22.1 4.7 0.00015 21.2 4.7 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SAM_2 PF07647.17 KFX87780.1 - 5.8e-10 39.1 0.0 1.5e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFX87780.1 - 1.5e-09 38.1 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KFX87780.1 - 0.0056 16.6 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 KFX87780.1 - 0.02 14.7 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pec_lyase_C PF00544.19 KFX87794.1 - 1.6e-42 145.5 10.5 2.1e-42 145.1 10.5 1.2 1 0 0 1 1 1 1 Pectate lyase GST_N_3 PF13417.6 KFX87795.1 - 2e-09 37.8 0.1 3.2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX87795.1 - 9e-09 35.5 0.0 2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX87795.1 - 3.7e-07 30.2 0.0 7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX87795.1 - 5.7e-07 29.7 0.0 1.3e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX87795.1 - 0.00039 20.7 0.0 0.00064 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX87795.1 - 0.00092 19.2 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hce2 PF14856.6 KFX87796.1 - 1.1e-16 61.0 0.0 1.6e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor zf-C2H2 PF00096.26 KFX87799.1 - 0.0023 18.3 6.9 0.08 13.4 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX87799.1 - 0.14 13.1 4.5 9.2 7.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger BRD4_CDT PF17105.5 KFX87799.1 - 6.2 6.5 6.7 15 5.3 6.7 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 AMP-binding PF00501.28 KFX87802.1 - 4.3e-29 101.4 0.0 5.1e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Hemerythrin PF01814.23 KFX87803.1 - 0.0054 17.4 0.1 0.0077 16.9 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DeoC PF01791.9 KFX87804.1 - 1.1e-12 48.1 1.0 1.7e-12 47.5 1.0 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 KFX87804.1 - 0.027 13.9 0.1 0.046 13.2 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ank_2 PF12796.7 KFX87806.1 - 6.8e-46 154.8 0.0 7.3e-13 48.9 0.0 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX87806.1 - 1.1e-31 105.3 0.0 0.001 19.4 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KFX87806.1 - 7.7e-27 93.3 0.2 1.9e-05 25.1 0.0 6.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFX87806.1 - 9.2e-27 92.3 0.8 0.0086 16.5 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFX87806.1 - 5.8e-20 71.1 4.4 3.6e-05 24.0 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) DUF676 PF05057.14 KFX87806.1 - 5.3e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KFX87806.1 - 0.0046 17.4 0.1 0.013 15.9 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX87806.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF829 PF05705.14 KFX87806.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.13 KFX87806.1 - 0.038 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein RabGAP-TBC PF00566.18 KFX87807.1 - 5.1e-46 157.0 0.0 8.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFX87807.1 - 1.9e-05 24.5 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KFX87807.1 - 8.7e-05 22.1 0.4 0.015 15.2 0.2 3.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFX87807.1 - 0.0043 16.5 1.5 0.096 12.3 0.8 3.3 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KFX87807.1 - 0.015 14.7 1.0 0.16 11.5 0.3 2.9 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 KFX87807.1 - 0.018 15.5 2.1 0.11 12.9 0.3 3.3 3 1 2 5 5 5 0 EF-hand domain pair PTPRCAP PF15713.5 KFX87807.1 - 5.7 7.2 14.8 0.75 10.1 3.6 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated NFACT-C PF11923.8 KFX87808.1 - 1.2e-38 131.2 0.8 1.2e-38 131.2 0.8 2.9 3 0 0 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KFX87808.1 - 6.5e-31 107.2 0.0 1.8e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KFX87808.1 - 2.1e-30 105.9 3.3 2.1e-30 105.9 3.3 3.6 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) zf-C3H1 PF10650.9 KFX87808.1 - 4.6e-13 48.6 2.0 7.5e-13 47.9 2.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain DUF1366 PF07104.11 KFX87808.1 - 0.72 9.6 4.7 4.5 7.0 4.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Myosin_head PF00063.21 KFX87809.1 - 5.2e-270 897.4 0.0 5.2e-270 897.4 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KFX87809.1 - 6.8e-12 45.0 0.1 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KFX87809.1 - 3.2e-11 41.9 104.7 3.2e-11 41.9 104.7 6.5 2 2 2 4 4 4 2 Myosin tail AAA_22 PF13401.6 KFX87809.1 - 0.035 14.4 0.0 0.035 14.4 0.0 5.5 6 0 0 6 6 6 0 AAA domain DUF2935 PF11155.8 KFX87809.1 - 5.6 7.3 17.6 9.1 6.6 4.0 6.3 4 3 0 4 4 4 0 Domain of unknown function (DUF2935) CTP_synth_N PF06418.14 KFX87810.1 - 1.4e-114 381.9 0.2 2e-114 381.4 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFX87810.1 - 1.6e-54 184.6 0.0 2.5e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFX87810.1 - 1.3e-05 25.0 0.3 0.00014 21.7 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KFX87810.1 - 0.007 16.4 0.0 0.023 14.8 0.0 1.8 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KFX87810.1 - 0.069 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase F-box PF00646.33 KFX87811.1 - 2.7e-05 23.9 0.6 8.7e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KFX87811.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 KFX87811.1 - 0.072 13.0 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KFX87813.1 - 0.0038 17.1 0.1 0.0095 15.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX87813.1 - 0.02 14.8 0.5 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KFX87813.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box Med27 PF11571.8 KFX87813.1 - 0.33 11.3 2.8 2.2 8.7 0.9 2.5 1 1 0 2 2 2 0 Mediator complex subunit 27 AA_permease PF00324.21 KFX87814.1 - 5.5e-127 424.3 41.9 6.2e-127 424.1 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX87814.1 - 2e-38 132.4 51.2 2.3e-38 132.1 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KFX87814.1 - 0.034 14.8 2.2 0.034 14.8 2.2 4.5 4 0 0 4 4 4 0 PrgI family protein DUF3593 PF12159.8 KFX87814.1 - 0.17 12.0 1.7 7.9 6.6 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) ABC1 PF03109.16 KFX87815.1 - 3.9e-20 72.2 0.0 5.3e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KFX87815.1 - 0.034 14.1 0.7 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX87815.1 - 0.18 11.4 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF2457 PF10446.9 KFX87817.1 - 2.4e-111 373.2 45.6 2.4e-111 373.2 45.6 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) CNDH2_C PF16858.5 KFX87817.1 - 0.76 9.6 15.7 0.23 11.3 10.0 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 KFX87817.1 - 1.7 6.8 37.2 0.23 9.6 29.2 2.1 2 0 0 2 2 2 0 Nop14-like family TFIIA PF03153.13 KFX87817.1 - 5.5 6.9 41.5 0.16 11.9 34.1 2.0 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Alpha_GJ PF03229.13 KFX87823.1 - 0.0033 18.0 0.8 0.012 16.1 0.2 2.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J Herpes_gE PF02480.16 KFX87823.1 - 0.031 13.0 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KFX87823.1 - 0.038 14.9 0.1 0.094 13.6 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RgpF PF05045.12 KFX87824.1 - 0.0068 15.2 0.2 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Rhamnan synthesis protein F RNA_pol_I_A49 PF06870.12 KFX87825.1 - 1.6e-94 316.9 1.4 2e-94 316.7 1.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HDOD PF08668.12 KFX87825.1 - 0.094 12.2 0.1 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 HDOD domain Ribosomal_L41 PF05162.13 KFX87826.1 - 2.1e-08 34.1 26.5 3.7e-08 33.3 26.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 Pkinase PF00069.25 KFX87827.1 - 9.7e-59 198.9 0.0 3e-58 197.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87827.1 - 3.5e-27 95.3 0.0 7.7e-27 94.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFX87827.1 - 8e-09 35.7 0.0 2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFX87827.1 - 4.1e-07 29.6 0.0 1.9e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX87827.1 - 9.2e-05 21.4 0.0 9.2e-05 21.4 0.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFX87827.1 - 0.0002 20.8 0.0 0.00049 19.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WSC PF01822.19 KFX87830.1 - 3.9e-10 39.8 8.4 3.9e-10 39.8 8.4 1.8 2 0 0 2 2 2 1 WSC domain Glyco_hydro_18 PF00704.28 KFX87833.1 - 2.1e-42 145.9 0.0 2.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3245 PF11595.8 KFX87840.1 - 5.4e-12 46.4 7.6 5.4e-12 46.4 7.6 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.10 KFX87841.1 - 2.3e-78 262.4 0.9 4.2e-78 261.6 0.9 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFX87841.1 - 1.2e-26 93.3 0.3 3.5e-26 91.9 0.3 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFX87841.1 - 3.1e-10 39.9 0.3 6e-10 38.9 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX87841.1 - 0.0013 18.6 0.9 0.023 14.4 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_S11 PF00411.19 KFX87841.1 - 0.074 13.5 0.8 24 5.4 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein S11 MIF4G_like_2 PF09090.11 KFX87842.1 - 0.28 10.6 0.0 0.4 10.1 0.0 1.1 1 0 0 1 1 1 0 MIF4G like Acetyltransf_10 PF13673.7 KFX87843.1 - 2.7e-06 27.4 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX87843.1 - 1.2e-05 25.4 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 KFX87843.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX87843.1 - 7.1e-05 23.2 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KFX87843.1 - 0.053 14.2 0.0 0.31 11.8 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.20 KFX87844.1 - 2.3e-59 201.1 1.9 2.8e-57 194.3 0.0 2.7 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KFX87844.1 - 0.0099 14.7 0.0 0.065 12.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Peptidase_M22 PF00814.25 KFX87844.1 - 0.026 14.2 0.4 0.13 12.0 0.1 2.3 3 0 0 3 3 3 0 Glycoprotease family TBCA PF02970.16 KFX87844.1 - 7.1 7.0 9.4 0.46 10.8 0.3 3.4 5 0 0 5 5 5 0 Tubulin binding cofactor A Mucin PF01456.17 KFX87844.1 - 8.5 6.4 27.5 3.2 7.7 1.3 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein Prefoldin_2 PF01920.20 KFX87845.1 - 2e-24 85.6 4.2 3.7e-24 84.7 4.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF2681 PF10883.8 KFX87845.1 - 0.036 14.5 0.3 0.036 14.5 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) Spc24 PF08286.11 KFX87845.1 - 1 9.6 5.4 11 6.4 1.5 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 KFX87845.1 - 3.5 8.1 5.8 0.52 10.7 0.4 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SspP PF08179.12 KFX87845.1 - 4.7 7.7 6.1 0.32 11.5 0.4 2.0 2 0 0 2 2 2 0 Small acid-soluble spore protein P family ANAPC10 PF03256.16 KFX87846.1 - 3.1e-51 173.6 0.0 4.5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) FYDLN_acid PF09538.10 KFX87846.1 - 0.5 11.1 6.7 0.93 10.2 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 KFX87846.1 - 6.3 4.9 7.3 8 4.5 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFX87847.1 - 2.4e-95 320.0 30.9 2.4e-95 320.0 30.9 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KFX87847.1 - 2.4e-21 75.8 0.0 6.3e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Spt20 PF12090.8 KFX87848.1 - 3.8e-46 157.6 0.0 3.8e-46 157.6 0.0 6.6 2 1 2 4 4 4 1 Spt20 family Hexapep PF00132.24 KFX87850.1 - 3.8e-07 29.6 1.9 0.00032 20.3 0.9 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KFX87850.1 - 4.6e-05 22.5 1.2 0.038 12.9 0.3 2.1 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 KFX87850.1 - 0.0017 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KFX87850.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KFX87850.1 - 0.034 12.3 0.5 0.058 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Dsh_C PF12316.8 KFX87850.1 - 0.11 12.8 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MPP6 PF10175.9 KFX87850.1 - 0.18 12.3 0.8 1.2 9.7 0.1 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Hexapep_2 PF14602.6 KFX87850.1 - 0.33 10.7 5.3 7.7 6.4 0.1 2.9 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Band_7 PF01145.25 KFX87851.1 - 2.4e-16 60.3 0.1 2.4e-16 60.3 0.1 2.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Peptidase_M28 PF04389.17 KFX87863.1 - 1.3e-31 109.9 0.0 2.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFX87863.1 - 2.9e-07 30.4 0.1 7.6e-07 29.0 0.1 1.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1774 PF08611.10 KFX87865.1 - 4e-36 123.2 1.8 4e-36 123.2 1.8 2.9 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) Pex24p PF06398.11 KFX87867.1 - 7e-31 107.5 0.0 8.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KFX87867.1 - 0.0068 14.9 0.0 0.0088 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) DUF4395 PF14340.6 KFX87867.1 - 0.11 12.9 0.4 0.22 11.8 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) Pkinase PF00069.25 KFX87868.1 - 6.2e-53 179.8 0.5 1.1e-52 179.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87868.1 - 1.1e-17 64.2 0.1 3e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX87868.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Catalase PF00199.19 KFX87870.1 - 8.7e-13 48.1 0.0 9.6e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Cu-oxidase_3 PF07732.15 KFX87871.1 - 1.3e-47 160.7 4.2 4.3e-47 159.0 0.2 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX87871.1 - 5.9e-40 136.2 6.6 4.8e-35 120.3 1.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KFX87871.1 - 6.3e-39 133.6 1.2 1.1e-37 129.7 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase DUF5620 PF18522.1 KFX87871.1 - 0.019 15.3 0.2 0.037 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Phosphoesterase PF04185.14 KFX87872.1 - 9.6e-35 120.4 3.8 2.4e-34 119.1 3.8 1.6 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KFX87872.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain RRM_1 PF00076.22 KFX87876.1 - 4.2e-26 90.6 0.0 7.5e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 KFX87877.1 - 5.6e-20 71.7 0.0 1.3e-19 70.5 0.0 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KFX87877.1 - 0.0013 18.8 0.1 0.0077 16.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX87877.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 KFX87877.1 - 2.6 7.3 7.0 3.5 6.9 7.0 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2235 PF09994.9 KFX87883.1 - 6.4e-20 71.7 0.1 9.7e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 KFX87884.1 - 3.2e-20 72.3 0.0 5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX87884.1 - 8.8e-08 32.2 14.3 0.0008 19.7 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX87884.1 - 8.2e-06 26.0 6.9 8.2e-06 26.0 6.9 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX87884.1 - 0.0014 19.3 13.3 0.17 12.8 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Aldedh PF00171.22 KFX87885.1 - 5.7e-186 618.5 0.6 6.4e-186 618.4 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECH_1 PF00378.20 KFX87886.1 - 1.2e-41 142.7 0.2 3.6e-41 141.1 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX87886.1 - 5.5e-29 101.7 0.1 3.1e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-NOSIP PF15906.5 KFX87886.1 - 0.015 15.4 0.1 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein 2OG-FeII_Oxy_2 PF13532.6 KFX87894.1 - 4.1e-30 105.5 0.0 2e-29 103.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KFX87894.1 - 8.6e-19 68.4 0.0 1.8e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Bud13 PF09736.9 KFX87894.1 - 3.9 7.9 5.4 1.1 9.6 1.9 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CDC50 PF03381.15 KFX87896.1 - 6.1e-91 304.8 0.0 9.1e-91 304.2 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SAE2 PF08573.10 KFX87896.1 - 1.8e-36 125.7 0.2 1.8e-36 125.7 0.2 2.4 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Asp4 PF16996.5 KFX87896.1 - 0.2 11.4 0.3 0.47 10.3 0.3 1.6 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 FACT-Spt16_Nlob PF14826.6 KFX87897.1 - 2.9e-56 189.7 0.2 8.8e-56 188.2 0.2 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KFX87897.1 - 3.1e-55 186.5 0.1 3.1e-55 186.5 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KFX87897.1 - 3.7e-24 85.6 0.0 6.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFX87897.1 - 6.2e-15 55.4 0.4 1.9e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2462 PF09495.10 KFX87898.1 - 3.4e-21 75.7 9.2 5.3e-21 75.1 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ERG4_ERG24 PF01222.17 KFX87899.1 - 6.5e-139 463.4 16.8 7.6e-139 463.2 16.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SRP-alpha_N PF04086.13 KFX87899.1 - 1.7 8.5 5.9 2.6 7.9 5.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal VCBS PF13517.6 KFX87900.1 - 2.4e-29 101.7 45.8 6.4e-12 45.9 1.5 6.0 3 1 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX87900.1 - 7.9e-14 52.4 0.9 1.8e-13 51.3 0.9 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX87900.1 - 1.2e-09 38.5 0.1 1.8e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 KFX87900.1 - 1.5e-05 25.0 20.2 0.022 14.9 0.4 5.4 4 0 0 4 4 4 4 FG-GAP repeat BBS2_C PF14782.6 KFX87900.1 - 0.0019 17.1 0.2 0.89 8.2 0.0 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal TcdB_toxin_midN PF12256.8 KFX87900.1 - 0.22 10.9 11.1 13 5.1 0.0 4.9 3 2 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region RCC1_2 PF13540.6 KFX87900.1 - 1.5 8.7 4.6 0.47 10.3 0.1 2.6 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat NIF PF03031.18 KFX87904.1 - 2.7e-41 140.9 0.0 3.7e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.25 KFX87907.1 - 8.5e-68 228.6 0.0 1.2e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87907.1 - 1.2e-50 172.3 0.0 1.7e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX87907.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFX87907.1 - 0.0017 17.7 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 KFX87907.1 - 0.021 15.0 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Haspin_kinase PF12330.8 KFX87907.1 - 0.15 10.9 0.0 7.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain tRNA-synt_1c PF00749.21 KFX87920.1 - 4.4e-98 328.0 0.0 5.7e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFX87920.1 - 2.7e-29 102.3 0.0 9.3e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3597 PF12200.8 KFX87920.1 - 0.041 14.4 1.0 0.079 13.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Ribosomal_60s PF00428.19 KFX87920.1 - 6.1 7.5 11.9 15 6.3 11.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macro PF01661.21 KFX87921.1 - 4.9e-40 136.2 0.3 8.6e-40 135.5 0.3 1.4 1 0 0 1 1 1 1 Macro domain ECH_1 PF00378.20 KFX87922.1 - 1.4e-43 149.1 0.0 2.7e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NMO PF03060.15 KFX87922.1 - 2.4e-39 135.6 0.2 3.9e-39 135.0 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ECH_2 PF16113.5 KFX87922.1 - 8.9e-20 71.4 0.0 3.6e-19 69.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FMN_dh PF01070.18 KFX87922.1 - 9.9e-05 21.5 2.0 0.00016 20.8 2.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KFX87922.1 - 0.025 13.6 1.4 0.042 12.8 1.4 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Peptidase_S49 PF01343.18 KFX87922.1 - 0.096 12.6 0.0 0.31 11.0 0.0 1.9 1 1 1 2 2 2 0 Peptidase family S49 Glu_synthase PF01645.17 KFX87922.1 - 0.14 11.3 0.3 0.22 10.6 0.3 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase Aldedh PF00171.22 KFX87923.1 - 7.4e-140 466.5 0.0 8.7e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFX87923.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Myb_Cef PF11831.8 KFX87924.1 - 2.9e-48 164.5 2.8 2.9e-48 164.5 2.8 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFX87924.1 - 3.5e-21 75.1 5.6 9.6e-10 38.5 0.8 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX87924.1 - 9e-19 67.5 5.2 2.8e-13 49.9 1.3 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KFX87924.1 - 0.046 13.8 4.1 0.082 13.0 0.0 3.0 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain BAG PF02179.16 KFX87924.1 - 0.49 10.9 5.2 0.84 10.1 2.9 2.7 2 0 0 2 2 2 0 BAG domain GILT PF03227.16 KFX87925.1 - 8.8e-19 67.7 0.1 1.7e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) AMP-binding PF00501.28 KFX87930.1 - 2e-41 142.0 0.2 2.4e-41 141.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX87930.1 - 1.2e-18 67.8 0.2 3.1e-18 66.5 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pal1 PF08316.11 KFX87934.1 - 9.2e-49 165.7 0.5 1.7e-48 164.9 0.5 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein DIOX_N PF14226.6 KFX87936.1 - 8.8e-20 71.6 0.0 1.8e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX87936.1 - 3.8e-14 53.0 0.0 7.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 KFX87937.1 - 1e-10 41.2 0.6 1e-10 41.2 0.6 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KFX87937.1 - 8.3e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFX87937.1 - 0.00098 19.0 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 KFX87937.1 - 0.0021 18.5 0.1 0.013 15.9 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase DMSP_lyase PF16867.5 KFX87937.1 - 0.057 13.1 0.2 0.057 13.1 0.2 1.9 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Adhesin_P1_N PF18652.1 KFX87937.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain MFS_1 PF07690.16 KFX87938.1 - 5.6e-31 107.7 36.9 3.5e-30 105.1 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CD225 PF04505.12 KFX87938.1 - 0.32 11.2 0.1 0.32 11.2 0.1 3.1 3 0 0 3 3 3 0 Interferon-induced transmembrane protein NADH-u_ox-rdase PF10785.9 KFX87938.1 - 0.41 11.4 4.9 1.5 9.5 1.5 3.5 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DIOX_N PF14226.6 KFX87939.1 - 4.1e-15 56.6 0.0 7.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX87939.1 - 2.8e-12 47.0 0.0 4.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF848 PF05852.11 KFX87940.1 - 0.13 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ApeA_NTD1 PF18862.1 KFX87940.1 - 0.28 10.7 0.0 0.31 10.6 0.0 1.0 1 0 0 1 1 1 0 ApeA N-terminal domain 1 FAD_binding_3 PF01494.19 KFX87941.1 - 5.2e-30 104.9 0.0 4.6e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX87941.1 - 6.1e-06 25.7 0.2 0.034 13.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KFX87941.1 - 1e-05 24.7 0.0 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.6 KFX87941.1 - 4.8e-05 22.8 0.0 0.084 12.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX87941.1 - 0.00026 20.7 0.8 0.52 9.8 1.3 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX87941.1 - 0.00053 19.0 0.0 0.12 11.2 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KFX87941.1 - 0.00094 19.7 0.0 0.78 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX87941.1 - 0.0023 18.1 0.2 0.0062 16.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX87941.1 - 0.0025 16.9 0.0 1.2 8.1 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KFX87941.1 - 0.0052 15.5 0.0 0.4 9.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KFX87941.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFX87941.1 - 0.011 15.8 0.2 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFX87941.1 - 0.057 12.5 0.2 0.11 11.5 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFX87941.1 - 0.078 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ACP PF06857.11 KFX87942.1 - 0.77 10.0 4.1 0.46 10.7 0.2 2.4 2 1 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) OPT PF03169.15 KFX87946.1 - 4.9e-99 332.7 18.8 5.5e-99 332.5 18.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gag_spuma PF03276.14 KFX87946.1 - 0.28 9.6 0.1 0.4 9.1 0.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Gpr1_Fun34_YaaH PF01184.19 KFX87948.1 - 6.2e-95 316.7 17.2 7.3e-95 316.4 17.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_transf_28 PF03033.20 KFX87950.1 - 2e-19 70.0 0.2 6.1e-13 49.0 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFX87950.1 - 8.6e-05 21.5 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 KFX87950.1 - 0.0036 17.6 0.0 0.064 13.6 0.0 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 KFX87950.1 - 0.048 13.7 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UL45 PF05473.12 KFX87950.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like FA_hydroxylase PF04116.13 KFX87951.1 - 1.1e-10 41.9 6.9 2.1e-10 41.0 6.9 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily CDP-OH_P_transf PF01066.21 KFX87952.1 - 8.8e-10 39.2 1.9 8.8e-10 39.2 1.9 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF805 PF05656.14 KFX87952.1 - 0.25 11.8 5.1 0.87 10.0 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) RimK PF08443.11 KFX87953.1 - 0.062 12.9 0.1 0.079 12.5 0.1 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Ribonucleas_3_3 PF14622.6 KFX87954.1 - 1.8e-12 47.5 0.0 2.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFX87954.1 - 8.5e-09 36.0 0.0 1.1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain YtxH PF12732.7 KFX87955.1 - 0.0011 19.5 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 YtxH-like protein DUF4574 PF15141.6 KFX87955.1 - 0.005 16.7 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SLAC1 PF03595.17 KFX87956.1 - 3.8e-95 318.9 60.9 4.4e-95 318.7 60.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3481 PF11980.8 KFX87956.1 - 0.11 12.2 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein Glyco_hydro_17 PF00332.18 KFX87958.1 - 4.4e-08 33.1 2.1 0.00027 20.7 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF5326 PF17260.2 KFX87958.1 - 0.67 10.1 1.9 1.2 9.4 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) adh_short PF00106.25 KFX87960.1 - 1e-28 100.1 0.1 2.3e-27 95.7 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX87960.1 - 2.5e-20 73.0 0.0 6.2e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX87960.1 - 1.6e-07 31.4 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX87960.1 - 0.00025 20.6 2.1 0.0011 18.5 2.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX87960.1 - 0.01 15.3 2.5 0.052 12.9 2.5 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase CARDB PF07705.11 KFX87960.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 CARDB PglL_A PF15864.5 KFX87960.1 - 0.39 10.5 2.0 0.89 9.3 2.0 1.6 1 0 0 1 1 1 0 Protein glycosylation ligase SET PF00856.28 KFX87966.1 - 8.5e-11 42.5 0.0 1.5e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFX87966.1 - 6.4e-06 26.2 9.6 6.4e-06 26.2 9.6 2.0 2 0 0 2 2 2 1 MYND finger Fer4_16 PF13484.6 KFX87966.1 - 0.14 13.1 0.4 0.14 13.1 0.4 2.8 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain zf-BED PF02892.15 KFX87966.1 - 3.2 7.8 6.8 0.29 11.2 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger AhpC-TSA PF00578.21 KFX87967.1 - 2.6e-30 104.9 0.0 3.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFX87967.1 - 5.7e-13 48.8 0.0 7.6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFX87967.1 - 4.3e-11 42.5 0.1 8.1e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.32 KFX87970.1 - 3.6e-06 27.6 0.1 2 9.4 0.0 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Securin PF04856.13 KFX87971.1 - 0.01 15.8 0.5 0.017 15.1 0.5 1.5 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.7 KFX87972.1 - 1.9e-51 174.0 34.2 2.2e-51 173.8 34.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KFX87972.1 - 1.1e-09 38.0 31.7 2.3e-06 27.2 17.9 2.6 1 1 1 2 2 2 2 Tropomyosin ERM PF00769.19 KFX87972.1 - 0.0012 18.7 33.3 0.0059 16.5 11.1 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 KFX87972.1 - 0.0016 18.8 33.7 0.14 12.6 12.0 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Jnk-SapK_ap_N PF09744.9 KFX87972.1 - 0.0023 18.2 33.0 0.0042 17.3 20.6 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 GAS PF13851.6 KFX87972.1 - 0.0034 16.8 32.2 0.0066 15.8 32.2 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KFX87972.1 - 0.0036 17.5 22.2 0.076 13.3 8.9 2.9 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein KELK PF15796.5 KFX87972.1 - 0.0037 17.7 31.7 0.009 16.4 1.4 4.0 1 1 3 4 4 4 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KFX87972.1 - 0.0042 16.0 31.8 0.0045 15.9 18.3 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein HOOK PF05622.12 KFX87972.1 - 0.0048 15.1 28.1 0.0086 14.3 28.1 1.4 1 1 0 1 1 1 1 HOOK protein Cep57_CLD_2 PF14197.6 KFX87972.1 - 0.0055 16.8 30.1 0.52 10.4 1.9 4.1 2 2 0 3 3 3 2 Centrosome localisation domain of PPC89 DUF724 PF05266.14 KFX87972.1 - 0.01 15.7 22.8 0.1 12.4 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HMMR_N PF15905.5 KFX87972.1 - 0.018 14.6 31.0 0.05 13.1 31.0 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KFX87972.1 - 0.018 15.1 2.1 0.018 15.1 2.1 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KFX87972.1 - 0.02 15.1 25.1 0.24 11.6 18.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 KFX87972.1 - 0.028 13.7 24.6 0.44 9.8 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) JAKMIP_CC3 PF16034.5 KFX87972.1 - 0.029 14.3 5.9 0.029 14.3 5.9 2.2 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF3584 PF12128.8 KFX87972.1 - 0.037 11.6 23.9 0.043 11.3 23.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 KFX87972.1 - 0.039 14.3 19.6 0.67 10.4 1.8 4.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_DsbA PF11126.8 KFX87972.1 - 0.085 13.1 1.0 0.085 13.1 1.0 2.5 2 1 1 3 3 2 0 Transcriptional regulator DsbA Seryl_tRNA_N PF02403.22 KFX87972.1 - 0.11 12.7 27.3 2.5 8.3 5.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 KFX87972.1 - 0.11 12.5 19.5 0.11 12.5 6.1 2.7 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.11 KFX87972.1 - 0.12 12.6 31.4 6.1 7.0 12.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 KFX87972.1 - 0.13 10.4 24.8 0.089 10.9 5.0 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 KFX87972.1 - 0.14 12.0 17.3 0.13 12.2 2.7 2.2 1 1 1 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KFX87972.1 - 0.16 12.0 14.7 0.32 11.0 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFX87972.1 - 0.18 12.3 36.3 3.6 8.1 21.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KFX87972.1 - 0.2 12.1 20.6 0.45 11.0 0.3 3.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DHR10 PF18595.1 KFX87972.1 - 0.21 11.7 32.1 1.5 8.9 4.5 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain MAD PF05557.13 KFX87972.1 - 0.24 9.7 28.8 1.2 7.4 13.3 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 KFX87972.1 - 0.26 11.7 27.0 0.43 11.0 26.2 1.6 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 KFX87972.1 - 0.29 11.2 31.2 4.1 7.5 13.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 KFX87972.1 - 0.29 11.2 35.5 0.11 12.6 4.8 5.2 3 1 1 5 5 5 0 Basic region leucine zipper DUF4763 PF15960.5 KFX87972.1 - 0.35 10.2 17.7 1.4 8.2 3.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) BLOC1_2 PF10046.9 KFX87972.1 - 0.35 11.2 22.6 4.1 7.8 0.4 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 KFX87972.1 - 0.36 10.4 27.4 0.68 9.5 27.4 1.4 1 1 0 1 1 1 0 Intermediate filament protein STAT_alpha PF01017.20 KFX87972.1 - 0.37 10.7 19.8 0.45 10.4 0.7 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Lebercilin PF15619.6 KFX87972.1 - 0.39 10.4 31.8 4.5 6.9 17.2 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 KFX87972.1 - 0.44 11.0 17.1 4 7.9 7.3 2.6 1 1 1 2 2 2 0 Type III cell invasion protein SipB Taxilin PF09728.9 KFX87972.1 - 0.48 9.5 29.5 1.5 7.9 8.6 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein SOGA PF11365.8 KFX87972.1 - 0.54 11.4 24.2 3.3 8.9 8.0 3.8 1 1 2 3 3 3 0 Protein SOGA ZapB PF06005.12 KFX87972.1 - 0.63 10.5 38.5 68 4.0 21.9 4.0 1 1 2 3 3 3 0 Cell division protein ZapB TANGO2 PF05742.12 KFX87972.1 - 0.82 9.7 8.6 1.5 8.8 8.2 1.7 1 1 0 1 1 1 0 Transport and Golgi organisation 2 bZIP_1 PF00170.21 KFX87972.1 - 0.92 9.7 31.1 1.8 8.7 2.7 4.8 2 1 3 5 5 5 0 bZIP transcription factor DUF745 PF05335.13 KFX87972.1 - 0.92 9.2 20.4 0.14 11.9 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4200 PF13863.6 KFX87972.1 - 1.1 9.7 31.9 2.4 8.6 17.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4201 PF13870.6 KFX87972.1 - 1.3 8.8 28.8 18 5.0 28.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) BST2 PF16716.5 KFX87972.1 - 1.3 9.7 26.1 0.24 12.0 1.0 3.2 1 1 2 3 3 2 0 Bone marrow stromal antigen 2 HAP1_N PF04849.13 KFX87972.1 - 1.3 8.2 29.8 20 4.3 29.8 2.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BRE1 PF08647.11 KFX87972.1 - 1.4 9.1 30.6 0.74 9.9 18.5 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.11 KFX87972.1 - 1.5 7.6 30.1 3.4 6.4 7.9 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 KFX87972.1 - 1.6 8.2 24.7 2.1 7.8 24.7 1.1 1 0 0 1 1 1 0 Leucine zipper USP8_interact PF08941.10 KFX87972.1 - 2.1 8.1 9.3 3.3 7.5 8.4 1.8 1 1 1 2 2 2 0 USP8 interacting YabA PF06156.13 KFX87972.1 - 2.2 9.0 26.4 19 6.0 7.5 3.1 1 1 2 3 3 3 0 Initiation control protein YabA NYD-SP28 PF14772.6 KFX87972.1 - 2.2 8.4 26.3 0.071 13.2 12.5 2.7 1 1 1 2 2 2 0 Sperm tail SlyX PF04102.12 KFX87972.1 - 2.3 8.9 19.2 1.8 9.2 5.9 3.3 1 1 3 4 4 4 0 SlyX TPR_MLP1_2 PF07926.12 KFX87972.1 - 2.3 8.3 35.3 17 5.5 26.9 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFX87972.1 - 2.5 7.1 22.9 1.4 7.9 14.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 KFX87972.1 - 3 8.3 12.6 96 3.5 5.4 4.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SHE3 PF17078.5 KFX87972.1 - 3 7.5 26.6 4.9 6.8 1.0 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 XhlA PF10779.9 KFX87972.1 - 3 8.1 28.4 0.6 10.4 3.3 4.0 1 1 3 4 4 4 0 Haemolysin XhlA DUF16 PF01519.16 KFX87972.1 - 3 8.4 22.4 14 6.3 2.4 3.0 1 1 1 2 2 1 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 KFX87972.1 - 3.3 7.2 15.7 4.7 6.7 15.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 KFX87972.1 - 3.4 7.9 22.8 3.5 7.9 7.4 2.9 1 1 2 3 3 3 0 Cortexillin I, coiled coil CENP-H PF05837.12 KFX87972.1 - 3.5 8.1 25.8 46 4.5 0.1 3.0 1 1 1 2 2 1 0 Centromere protein H (CENP-H) DUF4472 PF14739.6 KFX87972.1 - 3.5 8.4 27.3 1.8 9.3 9.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 KFX87972.1 - 3.6 7.7 35.1 2.6 8.1 7.5 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding CASP_C PF08172.12 KFX87972.1 - 3.7 6.8 21.4 0.17 11.2 1.9 2.1 1 1 1 2 2 2 0 CASP C terminal FapA PF03961.13 KFX87972.1 - 4.6 5.7 25.7 0.75 8.3 7.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 KFX87972.1 - 4.7 6.8 27.8 9.9 5.7 0.9 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KFX87972.1 - 5.5 6.3 22.7 31 3.8 22.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 KFX87972.1 - 5.7 6.9 28.3 2.4 8.1 4.7 4.0 1 1 3 4 4 4 0 Prefoldin subunit Lge1 PF11488.8 KFX87972.1 - 6.1 7.1 20.4 0.11 12.7 1.3 3.9 1 1 2 3 3 2 0 Transcriptional regulatory protein LGE1 FAP206 PF12018.8 KFX87972.1 - 6.6 6.2 14.1 0.26 10.7 5.6 2.0 1 1 1 2 2 2 0 Domain of unknown function KASH_CCD PF14662.6 KFX87972.1 - 6.9 6.5 31.3 3.7 7.3 20.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KFX87972.1 - 7.6 6.5 10.4 0.6 10.0 0.2 3.4 4 0 0 4 4 2 0 Shugoshin N-terminal coiled-coil region HemX PF04375.14 KFX87972.1 - 8.5 5.6 22.8 59 2.8 18.2 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fmp27_WPPW PF10359.9 KFX87972.1 - 9 5.0 24.3 0.25 10.1 8.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.6 KFX87972.1 - 9.1 4.8 25.7 55 2.2 25.7 1.8 1 1 0 1 1 1 0 AAA domain Nop25 PF09805.9 KFX87973.1 - 8.8e-38 129.9 12.6 8.8e-38 129.9 12.6 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.12 KFX87974.1 - 4.7e-06 26.5 0.1 9.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Fcf1 PF04900.12 KFX87975.1 - 7.6e-37 125.7 0.1 1.2e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFX87975.1 - 1.6e-12 47.8 0.5 4.1e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 PIN like domain LapA_dom PF06305.11 KFX87976.1 - 0.021 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SWI-SNF_Ssr4 PF08549.10 KFX87976.1 - 4.7 5.7 9.8 6.8 5.2 9.8 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Methyltransf_11 PF08241.12 KFX87978.1 - 9.2e-21 74.3 0.0 3.6e-20 72.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87978.1 - 1.8e-19 70.2 0.1 5.9e-19 68.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87978.1 - 7e-16 58.4 0.0 9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87978.1 - 4.4e-14 52.6 0.0 7.9e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX87978.1 - 1.1e-11 45.3 0.0 1.8e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFX87978.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KFX87978.1 - 2e-09 37.1 0.0 3.5e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFX87978.1 - 2.1e-07 31.0 0.1 3.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX87978.1 - 2.5e-07 30.6 0.0 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX87978.1 - 9.3e-07 28.6 0.0 1.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFX87978.1 - 1.4e-05 24.1 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KFX87978.1 - 2.6e-05 24.3 0.0 3.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KFX87978.1 - 5.5e-05 22.9 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TrmK PF04816.12 KFX87978.1 - 0.00011 21.8 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_15 PF09445.10 KFX87978.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KFX87978.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 KFX87978.1 - 0.00023 20.7 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KFX87978.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) GCD14 PF08704.10 KFX87978.1 - 0.0039 16.9 0.1 0.0086 15.8 0.1 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit TehB PF03848.14 KFX87978.1 - 0.0041 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 KFX87978.1 - 0.0056 16.3 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 KFX87978.1 - 0.016 16.2 0.1 0.031 15.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFX87978.1 - 0.078 12.4 0.0 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.15 KFX87978.1 - 0.16 11.8 0.0 1.6 8.5 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 KFX87982.1 - 1.7e-06 27.9 0.2 2.2e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFX87982.1 - 0.0021 17.7 0.2 0.0036 16.8 0.2 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.19 KFX87982.1 - 0.033 13.9 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFX87982.1 - 0.058 14.1 0.4 0.11 13.3 0.4 1.4 1 0 0 1 1 1 0 Methyltransferase domain LPD39 PF18858.1 KFX87982.1 - 0.19 11.8 0.1 0.23 11.6 0.1 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Zn_clus PF00172.18 KFX87983.1 - 0.00034 20.7 13.7 0.00056 20.0 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX87983.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sulfotransfer_4 PF17784.1 KFX87984.1 - 0.00016 21.6 0.0 0.69 9.7 0.0 2.5 2 1 1 3 3 3 2 Sulfotransferase domain RTA1 PF04479.13 KFX87985.1 - 4.4e-75 251.8 8.0 6.9e-75 251.2 8.0 1.3 1 0 0 1 1 1 1 RTA1 like protein AstE_AspA PF04952.14 KFX87986.1 - 1.8e-26 92.9 0.0 1.1e-18 67.3 0.0 2.2 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.16 KFX87987.1 - 2.4e-35 122.1 31.8 3.5e-35 121.6 31.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX87987.1 - 1.9e-08 34.0 2.2 1.9e-08 34.0 2.2 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sec1 PF00995.23 KFX87988.1 - 6.9e-105 352.4 0.2 8.7e-105 352.1 0.2 1.1 1 0 0 1 1 1 1 Sec1 family Cyclin PF08613.11 KFX87991.1 - 2.3e-40 138.6 0.2 8.4e-25 88.0 0.2 2.4 2 0 0 2 2 2 2 Cyclin Pkinase PF00069.25 KFX88000.1 - 1.7e-11 44.0 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX88000.1 - 3.6e-05 23.8 0.5 6.1e-05 23.1 0.5 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX88000.1 - 8.6e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFX88000.1 - 0.00017 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFX88000.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KFX88000.1 - 0.12 11.9 0.7 0.2 11.2 0.7 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KFX88000.1 - 0.19 10.5 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fungal_trans_2 PF11951.8 KFX88001.1 - 1.5e-77 261.0 0.0 1.8e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88001.1 - 2e-07 31.0 10.9 3.7e-07 30.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERO1 PF04137.15 KFX88002.1 - 3.9e-134 447.3 0.0 6.7e-134 446.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Defb50 PF17546.2 KFX88002.1 - 8.8 6.3 6.2 49 3.9 0.0 3.1 3 0 0 3 3 3 0 Beta defensin 50 Pal1 PF08316.11 KFX88003.1 - 9.8e-07 29.6 0.1 2e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.9 KFX88004.1 - 9.4e-81 270.8 0.0 1.1e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein PSP1 PF04468.12 KFX88008.1 - 5.8e-27 93.8 1.9 1e-26 93.0 1.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NifU PF01106.17 KFX88009.1 - 3e-26 91.3 0.1 5e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 KFX88009.1 - 3.2e-18 65.5 0.0 1.1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 KFX88009.1 - 0.011 15.9 0.0 0.054 13.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF2052 PF09747.9 KFX88011.1 - 1.8e-12 47.8 0.1 3e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.6 KFX88012.1 - 8.9e-61 205.8 0.0 1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX88012.1 - 3.4e-05 23.5 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFX88012.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Herpes_DNAp_acc PF04929.12 KFX88012.1 - 0.053 12.5 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Yip1 PF04893.17 KFX88018.1 - 5.6e-13 49.0 14.3 5.6e-13 49.0 14.3 1.7 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 KFX88018.1 - 0.036 13.6 3.5 0.091 12.3 2.4 2.0 2 1 0 2 2 2 0 YIF1 DDDD PF10161.9 KFX88018.1 - 0.096 12.5 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Glyco_hydro_26 PF02156.15 KFX88019.1 - 6.3e-76 255.8 1.6 8.4e-76 255.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KFX88019.1 - 9.3e-48 161.5 11.1 8.1e-25 87.4 1.7 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) bMG6 PF17962.1 KFX88019.1 - 0.00099 19.2 0.2 6.9 6.9 0.0 3.6 3 0 0 3 3 3 2 Bacterial macroglobulin domain 6 DUF5010_C PF18099.1 KFX88019.1 - 0.0026 17.9 0.7 0.0071 16.5 0.2 1.9 2 0 0 2 2 2 1 DUF5010 C-terminal domain VirC2 PF07181.11 KFX88019.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 VirC2 protein YiaAB PF05360.14 KFX88019.1 - 0.22 11.8 0.1 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 yiaA/B two helix domain Methyltransf_11 PF08241.12 KFX88020.1 - 1.3e-18 67.5 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX88020.1 - 7.5e-15 55.4 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX88020.1 - 5.3e-11 43.1 0.0 8.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX88020.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX88020.1 - 1.9e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KFX88020.1 - 0.00017 20.8 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 KFX88020.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KFX88020.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 KFX88020.1 - 0.05 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KFX88020.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KFX88020.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase EF-hand_7 PF13499.6 KFX88021.1 - 6.6e-12 45.7 0.6 4.4e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFX88021.1 - 3.6e-09 35.8 0.4 0.015 15.2 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 KFX88021.1 - 1.3e-08 35.1 0.0 0.0083 16.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFX88021.1 - 2.5e-08 32.9 0.1 0.027 14.0 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFX88021.1 - 4.3e-06 26.5 0.1 7.4e-05 22.5 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KFX88021.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) ABC_membrane PF00664.23 KFX88026.1 - 2.9e-88 296.1 24.5 5.1e-50 170.7 7.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX88026.1 - 2.3e-49 167.4 0.0 1.1e-28 100.4 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX88026.1 - 4.6e-09 36.1 4.3 0.016 14.6 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFX88026.1 - 1.1e-05 25.4 0.2 0.16 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX88026.1 - 7.5e-05 23.2 0.8 0.012 16.1 0.5 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX88026.1 - 0.00041 20.3 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFX88026.1 - 0.00048 19.8 0.5 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KFX88026.1 - 0.0011 19.0 0.8 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KFX88026.1 - 0.0028 18.2 0.2 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFX88026.1 - 0.01 15.7 1.6 1 9.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX88026.1 - 0.011 15.5 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KFX88026.1 - 0.019 14.0 0.0 0.3 10.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KFX88026.1 - 0.043 13.9 5.3 2.1 8.4 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 KFX88026.1 - 0.057 13.2 1.1 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KFX88026.1 - 0.059 13.6 0.1 15 5.8 0.0 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KFX88026.1 - 0.075 12.4 0.3 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KFX88026.1 - 0.12 12.0 1.3 12 5.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX88026.1 - 0.13 12.6 0.0 9 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KFX88026.1 - 0.15 12.0 0.3 1 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain CDC45 PF02724.14 KFX88026.1 - 0.2 9.9 1.1 0.3 9.3 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 KFX88026.1 - 0.43 10.8 2.6 45 4.3 0.3 3.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 KFX88026.1 - 0.55 9.5 2.0 7.4 5.8 0.1 2.5 2 0 0 2 2 2 0 AIG1 family 60KD_IMP PF02096.20 KFX88026.1 - 2.1 8.2 11.0 0.28 11.1 5.8 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein HLH PF00010.26 KFX88027.1 - 3.3e-12 46.2 0.3 5.8e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_UL6 PF01763.16 KFX88027.1 - 0.022 13.3 1.3 0.035 12.6 1.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like GIT1_C PF12205.8 KFX88027.1 - 0.064 13.4 0.9 0.47 10.6 0.9 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF3450 PF11932.8 KFX88027.1 - 2.5 7.3 10.3 0.47 9.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CLTH PF10607.9 KFX88028.1 - 8.8e-35 119.8 0.0 1.7e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFX88028.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 0 LisH IL28A PF15177.6 KFX88028.1 - 0.023 14.5 1.5 0.041 13.7 1.5 1.3 1 0 0 1 1 1 0 Interleukin-28A NDUF_B12 PF08122.12 KFX88029.1 - 8.9e-26 89.7 0.7 1.5e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Thiolase_N PF00108.23 KFX88031.1 - 3.7e-89 298.5 0.4 5.4e-89 298.0 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX88031.1 - 4.1e-38 129.8 0.4 4.1e-38 129.8 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX88031.1 - 7.4e-07 29.0 1.8 1.5e-06 28.0 0.8 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Aldo_ket_red PF00248.21 KFX88033.1 - 5.9e-52 176.7 0.0 6.7e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Esterase_phd PF10503.9 KFX88034.1 - 9.2e-25 87.4 2.8 1.3e-24 87.0 2.8 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX88034.1 - 4.9e-13 49.0 0.6 6.9e-13 48.6 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KFX88034.1 - 0.00038 20.3 8.6 0.00038 20.3 8.6 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Esterase PF00756.20 KFX88034.1 - 0.025 14.2 2.0 0.054 13.1 2.0 1.6 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 KFX88034.1 - 0.027 15.1 0.6 0.052 14.1 0.5 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 KFX88034.1 - 0.038 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KFX88034.1 - 0.1 12.1 0.2 0.23 11.0 0.1 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KFX88034.1 - 0.13 11.9 1.0 0.82 9.3 0.4 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFX88034.1 - 0.17 11.0 0.2 0.25 10.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 KFX88034.1 - 0.18 11.6 0.6 0.73 9.6 0.6 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ribonuclease PF00545.20 KFX88035.1 - 1.2e-10 41.9 0.0 2.8e-10 40.8 0.0 1.6 1 1 1 2 2 2 1 ribonuclease DUF3632 PF12311.8 KFX88036.1 - 1.1e-36 127.0 1.3 1.3e-36 126.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Epimerase PF01370.21 KFX88037.1 - 3.3e-11 43.1 0.0 4.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX88037.1 - 3.7e-10 40.0 0.1 6.5e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX88037.1 - 3.3e-07 30.1 0.3 6.5e-07 29.1 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KFX88037.1 - 4.4e-05 22.8 0.3 0.00048 19.4 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFX88037.1 - 7.7e-05 22.0 0.0 0.00025 20.3 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX88037.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX88037.1 - 0.00056 19.0 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX88037.1 - 0.00068 18.8 0.1 0.038 13.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KFX88037.1 - 0.0029 17.5 0.1 0.0067 16.3 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KFX88037.1 - 0.0075 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 KFX88037.1 - 0.011 16.3 0.1 0.027 15.1 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFX88037.1 - 0.018 15.3 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KFX88037.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAM180 PF15173.6 KFX88037.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FAM180 family SpoU_methylas_C PF12105.8 KFX88037.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal NAD_binding_3 PF03447.16 KFX88037.1 - 0.083 13.6 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFX88037.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NUDIX_2 PF13869.6 KFX88038.1 - 1.3e-81 272.7 0.0 1.5e-81 272.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.17 KFX88039.1 - 4.5e-37 126.7 0.0 2.3e-36 124.4 0.0 2.2 3 0 0 3 3 3 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KFX88039.1 - 8.1e-12 44.7 0.4 1.5e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88039.1 - 5.6e-08 32.8 10.2 9.4e-08 32.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRI3BP PF14965.6 KFX88039.1 - 0.16 11.5 1.5 17 4.9 0.0 3.1 2 1 0 2 2 2 0 Negative regulator of p53/TP53 AMP-binding PF00501.28 KFX88042.1 - 5.5e-32 110.9 0.0 6.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX88042.1 - 1.2e-11 45.4 0.0 4.3e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain ChaC PF04752.12 KFX88046.1 - 8.8e-57 192.0 0.0 1e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Epimerase PF01370.21 KFX88047.1 - 2.9e-11 43.3 0.0 4.5e-08 32.8 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX88047.1 - 3.6e-06 26.6 0.4 1e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX88047.1 - 4.2e-06 26.0 0.1 7.7e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFX88047.1 - 0.00039 20.0 0.3 0.00061 19.4 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX88047.1 - 0.0013 18.7 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFX88047.1 - 0.0025 16.9 0.2 0.2 10.7 0.2 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 KFX88047.1 - 0.003 17.8 0.3 0.0065 16.7 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFX88047.1 - 0.005 16.8 0.4 0.0086 16.0 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFX88047.1 - 0.023 13.9 0.4 0.26 10.4 0.4 2.2 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 KFX88047.1 - 0.041 13.0 0.2 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 KFX88048.1 - 5.6e-07 29.6 10.6 1.2e-06 28.5 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KFX88050.1 - 8.7e-21 73.5 0.0 1.1e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX88050.1 - 0.0031 17.6 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 KFX88050.1 - 0.039 12.8 0.1 0.047 12.5 0.1 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) WD40 PF00400.32 KFX88056.1 - 1.3e-102 332.8 38.5 1.6e-10 41.4 0.2 12.9 12 0 0 12 12 12 11 WD domain, G-beta repeat SesA PF17107.5 KFX88056.1 - 8.7e-34 116.3 0.0 2.4e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ANAPC4_WD40 PF12894.7 KFX88056.1 - 5.7e-29 100.3 9.4 0.15 12.4 0.0 11.8 1 1 10 11 11 11 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX88056.1 - 9.5e-14 50.9 0.2 7.3 6.7 0.0 10.0 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 KFX88056.1 - 6.1e-12 45.8 0.4 1.6e-11 44.4 0.4 1.7 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KFX88056.1 - 4e-11 42.4 11.9 0.093 11.7 0.0 9.1 1 1 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX88056.1 - 4.7e-10 39.7 3.8 0.011 15.7 0.0 4.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A SH3_18 PF18354.1 KFX88056.1 - 0.00033 20.6 0.0 32 4.7 0.0 6.3 5 1 1 6 6 6 0 CarS bacterial SH3 domain CobA_CobO_BtuR PF02572.15 KFX88056.1 - 0.013 15.8 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Epimerase PF01370.21 KFX88056.1 - 0.027 13.9 0.2 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KAP_NTPase PF07693.14 KFX88056.1 - 0.085 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Gmad1 PF10647.9 KFX88056.1 - 0.12 12.1 1.6 1.3e+02 2.1 0.0 4.7 3 2 2 5 5 5 0 Lipoprotein LpqB beta-propeller domain Tli4_C PF18426.1 KFX88056.1 - 0.24 11.7 2.1 81 3.5 0.0 4.7 7 0 0 7 7 6 0 Tle cognate immunity protein 4 C-terminal domain Thiolase_C PF02803.18 KFX88064.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Thiolase, C-terminal domain MtrA PF04208.14 KFX88065.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A AA_permease_2 PF13520.6 KFX88066.1 - 6.4e-54 183.4 52.7 8e-54 183.1 52.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX88066.1 - 1.5e-22 79.9 45.6 2e-22 79.5 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease GP41 PF00517.17 KFX88067.1 - 0.36 10.7 3.1 0.67 9.8 3.1 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Acetyltransf_10 PF13673.7 KFX88068.1 - 4.3e-10 39.6 0.0 1.5e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX88068.1 - 1.3e-08 35.2 0.0 3.9e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX88068.1 - 2.7e-08 34.0 0.0 5.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFX88068.1 - 0.0001 22.4 0.0 0.0059 16.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX88068.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFX88068.1 - 0.024 14.6 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cu-oxidase_3 PF07732.15 KFX88072.1 - 2.9e-36 124.1 0.9 1.6e-35 121.7 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX88072.1 - 5.8e-25 87.6 6.2 3.5e-20 72.1 0.1 4.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFX88072.1 - 4.4e-13 49.6 0.0 1.1e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase Arm-DNA-bind_3 PF13356.6 KFX88072.1 - 0.15 12.4 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain COesterase PF00135.28 KFX88075.1 - 1.3e-79 268.5 0.0 1.8e-79 267.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF1264 PF06884.11 KFX88075.1 - 7.8e-77 256.7 0.0 1.1e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.13 KFX88075.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 KFX88076.1 - 1.1e-85 287.7 26.1 1.1e-45 156.4 7.4 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX88076.1 - 1.2e-64 217.0 0.1 7.2e-32 110.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX88076.1 - 3.5e-14 52.8 0.1 0.00011 21.7 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX88076.1 - 1.5e-06 28.5 1.9 0.25 11.6 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KFX88076.1 - 8.3e-06 25.4 0.2 0.21 11.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX88076.1 - 1.5e-05 25.5 1.2 0.12 12.7 0.2 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFX88076.1 - 1.9e-05 24.7 3.8 0.98 9.2 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX88076.1 - 3.7e-05 23.7 0.2 0.31 10.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 KFX88076.1 - 0.00012 22.2 1.0 0.38 11.0 0.2 4.0 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KFX88076.1 - 0.00033 21.2 0.0 0.99 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX88076.1 - 0.00059 19.6 2.6 2.8 7.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 KFX88076.1 - 0.0018 17.9 0.2 5.5 6.5 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KFX88076.1 - 0.0049 17.0 0.3 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFX88076.1 - 0.0065 15.8 0.0 0.5 9.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 KFX88076.1 - 0.0076 16.2 0.3 4.1 7.3 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.14 KFX88076.1 - 0.013 15.5 0.1 6 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ECH_2 PF16113.5 KFX88076.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ABC_ATPase PF09818.9 KFX88076.1 - 0.045 12.5 0.2 4.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 KFX88076.1 - 0.07 13.6 0.8 42 4.6 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KFX88076.1 - 0.15 11.5 0.1 17 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KFX88076.1 - 0.17 12.3 0.1 28 5.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain Cad PF03596.13 KFX88076.1 - 0.21 11.5 5.8 0.057 13.3 0.7 2.4 2 0 0 2 2 2 0 Cadmium resistance transporter Acetyltransf_3 PF13302.7 KFX88077.1 - 2.9e-20 73.4 0.0 1.7e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX88077.1 - 0.059 13.6 0.0 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 KFX88078.1 - 1.8e-10 40.3 60.6 6.3e-10 38.5 53.0 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4235 PF14019.6 KFX88078.1 - 1.8 8.7 5.4 2.1 8.5 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4235) Esterase PF00756.20 KFX88079.1 - 1.4e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFX88079.1 - 3.1e-06 26.8 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX88079.1 - 7.6e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX88079.1 - 0.025 15.2 0.1 0.037 14.6 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 KFX88083.1 - 1.4e-08 34.7 7.1 2e-08 34.2 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 KFX88085.1 - 5.7e-211 701.6 0.6 7.8e-211 701.2 0.6 1.2 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.25 KFX88085.1 - 1.4e-44 152.4 0.0 1.7e-43 148.9 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88085.1 - 9.7e-27 93.9 0.0 2.4e-26 92.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX88085.1 - 0.028 13.2 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase 5_nucleotid_C PF02872.18 KFX88085.1 - 0.14 12.4 0.0 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain PDE8 PF08629.10 KFX88092.1 - 0.71 9.9 3.0 3.5 7.7 3.0 2.2 1 1 0 1 1 1 0 PDE8 phosphodiesterase Cpn60_TCP1 PF00118.24 KFX88093.1 - 6.7e-84 282.3 12.0 1.2e-83 281.4 12.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 KFX88093.1 - 7.6e-30 103.2 0.0 1.6e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.7 KFX88094.1 - 3.4e-35 121.6 0.0 5e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KFX88094.1 - 8.6e-21 73.3 0.8 1.4e-20 72.6 0.8 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain Methyltr_RsmB-F PF01189.17 KFX88095.1 - 1.2e-79 266.7 0.0 2.1e-79 265.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFX88095.1 - 1.6e-07 31.7 0.0 5.8e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 KFX88095.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Fungal_trans_2 PF11951.8 KFX88096.1 - 5.4e-19 68.3 3.6 1.6e-18 66.7 3.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88096.1 - 3e-07 30.5 13.4 5.2e-07 29.7 13.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydro_lipase PF04083.16 KFX88096.1 - 0.053 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NmrA PF05368.13 KFX88097.1 - 2.6e-33 115.5 0.0 3.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX88097.1 - 1.2e-10 41.6 0.1 2.2e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX88097.1 - 4e-06 26.0 0.0 5.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFX88097.1 - 8.9e-05 22.1 0.2 0.00015 21.3 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KFX88097.1 - 0.036 13.5 0.0 0.096 12.1 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 KFX88097.1 - 0.061 13.2 0.2 0.12 12.3 0.2 1.6 1 1 0 1 1 1 0 KR domain AMP-binding_C PF13193.6 KFX88097.1 - 0.063 14.3 0.2 1.2 10.2 0.2 2.5 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_15 PF09445.10 KFX88097.1 - 0.084 12.5 0.0 0.93 9.0 0.0 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF4244 PF14029.6 KFX88097.1 - 0.41 10.1 3.0 1.2 8.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) ATP-synt_Eps PF04627.13 KFX88101.1 - 8.6e-19 67.3 1.1 1.5e-18 66.5 1.1 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 KFX88102.1 - 9.1e-59 197.7 0.3 1.8e-58 196.8 0.3 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FCH PF00611.23 KFX88103.1 - 3.4e-16 59.3 1.0 5.1e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KFX88103.1 - 1.2e-12 47.2 0.0 2.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX88103.1 - 1.5e-10 40.6 0.0 1.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFX88103.1 - 6.4e-10 38.7 0.1 1.3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Rapsyn_N PF10579.9 KFX88103.1 - 0.082 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Not1 PF04054.15 KFX88104.1 - 2e-140 467.9 0.0 4.5e-140 466.7 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KFX88104.1 - 2.7e-95 318.0 2.9 5.7e-95 317.0 2.9 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KFX88104.1 - 1.8e-46 157.7 6.1 4.4e-46 156.4 6.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KFX88104.1 - 2.8e-43 147.3 0.0 1.2e-42 145.3 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KFX88104.1 - 1.5e-34 119.2 0.3 5.2e-34 117.5 0.3 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat NTF2 PF02136.20 KFX88106.1 - 2.4e-29 102.3 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KFX88106.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Cg6151-P PF10233.9 KFX88107.1 - 2.8e-42 143.6 14.1 3.4e-42 143.3 14.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF3566 PF12089.8 KFX88107.1 - 0.15 12.4 6.2 0.16 12.3 5.1 1.6 1 1 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Dpy19 PF10034.9 KFX88107.1 - 0.88 7.7 9.4 1.1 7.4 9.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2721 PF11026.8 KFX88107.1 - 7.8 6.4 13.4 13 5.7 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Aim21 PF11489.8 KFX88108.1 - 2.8e-200 667.9 73.5 2.8e-200 667.9 73.5 2.5 3 1 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Plasmodium_HRP PF05403.11 KFX88108.1 - 2.4e-06 27.5 8.7 1.1e-05 25.3 9.4 1.6 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) RMI1_N PF08585.12 KFX88108.1 - 5.1 6.8 7.2 14 5.4 7.2 1.7 1 0 0 1 1 1 0 RecQ mediated genome instability protein RNase_H2-Ydr279 PF09468.10 KFX88109.1 - 1.2e-42 145.8 0.0 3.2e-42 144.4 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFX88109.1 - 5.9e-26 90.5 0.0 1.4e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Ntox15 PF15604.6 KFX88109.1 - 0.12 12.5 2.9 0.21 11.7 2.9 1.4 1 0 0 1 1 1 0 Novel toxin 15 zf-primase PF09329.11 KFX88110.1 - 1.2e-20 73.0 1.4 2.2e-20 72.2 1.4 1.5 1 0 0 1 1 1 1 Primase zinc finger MutS_V PF00488.21 KFX88111.1 - 7.4e-48 163.1 0.1 1.4e-47 162.2 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX88111.1 - 4.2e-20 72.8 0.0 1.3e-19 71.2 0.0 1.9 2 0 0 2 2 2 1 MutS domain III UxuA PF03786.13 KFX88111.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) MMgT PF10270.9 KFX88112.1 - 9.4e-37 125.4 0.0 1.1e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 KFX88113.1 - 3.5e-31 107.2 0.8 3.5e-31 107.2 0.8 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFX88113.1 - 7.1e-14 52.0 8.1 7.1e-14 52.0 8.1 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KFX88113.1 - 0.0004 20.5 0.8 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX88113.1 - 0.03 14.5 2.3 0.051 13.8 0.2 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 KFX88113.1 - 0.041 13.6 0.9 0.051 13.3 0.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_2 PF13410.6 KFX88113.1 - 0.12 12.4 0.1 1.1 9.4 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 KFX88114.1 - 3.6e-46 157.4 0.3 6.1e-45 153.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFX88114.1 - 9.3e-34 115.5 0.9 9.3e-34 115.5 0.9 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KFX88114.1 - 2.3e-26 91.7 0.3 2.3e-26 91.7 0.3 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFX88114.1 - 5.1e-20 72.2 0.1 2.3e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX88114.1 - 3e-13 49.9 0.0 7.5e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFX88114.1 - 4.1e-08 33.1 0.4 2.1e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KFX88114.1 - 4.4e-08 33.7 8.6 0.00084 19.8 0.1 4.4 3 2 1 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KFX88114.1 - 1.5e-07 31.5 0.1 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KFX88114.1 - 1e-06 28.9 1.9 1.3 8.9 0.1 4.0 2 2 1 3 3 3 3 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFX88114.1 - 4e-06 27.1 2.0 0.088 13.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 KFX88114.1 - 6.3e-06 25.7 0.1 0.0022 17.4 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KFX88114.1 - 7.3e-06 25.8 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KFX88114.1 - 2.8e-05 23.7 0.0 0.3 10.6 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KFX88114.1 - 5.3e-05 23.5 0.6 0.048 13.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KFX88114.1 - 6.1e-05 23.6 6.4 1.4 9.3 5.5 3.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFX88114.1 - 9.5e-05 22.4 0.0 0.8 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFX88114.1 - 0.00056 19.7 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFX88114.1 - 0.001 19.6 0.5 1 9.8 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 KFX88114.1 - 0.0014 18.1 0.0 0.67 9.3 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFX88114.1 - 0.0016 18.8 0.0 0.91 9.9 0.0 3.0 2 1 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 KFX88114.1 - 0.0018 18.2 0.1 1.7 8.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KFX88114.1 - 0.002 18.7 5.1 1.5 9.4 0.0 3.9 3 1 0 4 4 3 2 AAA domain TsaE PF02367.17 KFX88114.1 - 0.0022 18.0 0.1 3.2 7.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFX88114.1 - 0.0038 17.0 1.9 0.19 11.4 0.4 3.4 3 1 0 3 3 3 1 AAA domain ERM PF00769.19 KFX88114.1 - 0.0043 16.9 9.3 0.0077 16.1 9.3 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Roc PF08477.13 KFX88114.1 - 0.0049 17.1 0.0 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KFX88114.1 - 0.0051 16.0 0.5 0.1 11.7 0.2 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KFX88114.1 - 0.0055 16.0 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 KFX88114.1 - 0.0085 16.1 0.3 3.4 7.6 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 KFX88114.1 - 0.0089 16.2 0.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KFX88114.1 - 0.01 15.3 0.1 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KFX88114.1 - 0.011 16.0 1.5 0.62 10.4 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.6 KFX88114.1 - 0.029 14.2 2.0 1 9.1 0.0 3.6 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 KFX88114.1 - 0.034 13.8 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 KFX88114.1 - 0.041 13.0 0.0 2.3 7.3 0.0 2.6 3 0 0 3 3 2 0 PIF1-like helicase NTPase_1 PF03266.15 KFX88114.1 - 0.042 13.7 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KFX88114.1 - 0.044 13.4 0.1 0.88 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX88114.1 - 0.06 12.5 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.12 KFX88114.1 - 0.069 12.9 0.1 3.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KFX88114.1 - 0.12 12.2 0.1 5.9 6.7 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain NYD-SP28 PF14772.6 KFX88114.1 - 0.34 11.0 12.0 0.9 9.6 12.0 1.7 1 0 0 1 1 1 0 Sperm tail FliL PF03748.14 KFX88114.1 - 1.1 9.9 3.8 17 6.1 0.0 3.1 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL DUF4349 PF14257.6 KFX88114.1 - 1.1 8.6 13.8 3.2 7.1 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Seryl_tRNA_N PF02403.22 KFX88114.1 - 4.5 7.5 16.3 5.4 7.3 13.0 2.9 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain OEP PF02321.18 KFX88114.1 - 8.3 6.2 12.8 15 5.3 12.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein AdoHcyase PF05221.17 KFX88115.1 - 5.2e-130 433.0 0.0 7.3e-74 248.6 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFX88115.1 - 2.2e-82 274.9 3.2 3.3e-82 274.4 3.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX88115.1 - 2.5e-07 30.2 0.1 5.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFX88115.1 - 0.0012 18.7 0.8 0.0041 16.9 0.5 1.9 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 KFX88115.1 - 0.0017 17.9 0.4 0.0033 17.0 0.4 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TMEM107 PF14995.6 KFX88115.1 - 0.064 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 3HCDH_N PF02737.18 KFX88115.1 - 0.08 12.8 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.21 KFX88116.1 - 7.2e-09 35.6 0.7 1e-07 31.9 0.7 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.27 KFX88118.1 - 8.7e-46 153.8 0.4 5.1e-20 71.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 KFX88121.1 - 2.3e-16 59.4 0.0 7.9e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX88121.1 - 0.043 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFX88121.1 - 0.082 12.7 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DLIC PF05783.11 KFX88122.1 - 1.9e-35 122.6 0.2 3e-33 115.4 0.0 3.1 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KFX88123.1 - 2.4e-18 65.7 0.0 4.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX88123.1 - 0.00034 20.7 0.0 0.0007 19.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KFX88123.1 - 0.2 11.7 0.6 0.73 9.9 0.0 2.1 1 1 1 2 2 2 0 RNA binding motif WD40 PF00400.32 KFX88124.1 - 2.8e-05 24.8 0.1 0.43 11.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88124.1 - 0.03 14.6 0.0 0.58 10.5 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Septin PF00735.18 KFX88125.1 - 7.1e-107 356.9 0.1 1.7e-106 355.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFX88125.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 KFX88125.1 - 0.00052 19.2 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KFX88125.1 - 0.00073 19.6 6.6 0.01 15.9 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KFX88125.1 - 0.0028 17.2 0.7 0.17 11.4 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFX88125.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 KFX88125.1 - 0.021 15.3 0.4 0.12 12.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 KFX88125.1 - 0.035 13.5 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KFX88125.1 - 0.1 12.5 4.9 0.083 12.8 0.5 2.7 3 1 0 3 3 3 0 RsgA GTPase DUF87 PF01935.17 KFX88125.1 - 0.22 11.6 2.7 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Ribosomal_S17e PF00833.18 KFX88125.1 - 0.27 11.2 4.5 0.58 10.1 4.5 1.5 1 0 0 1 1 1 0 Ribosomal S17 AAA_23 PF13476.6 KFX88125.1 - 1.4 9.4 9.0 9.1 6.7 4.0 2.3 2 1 0 2 2 2 0 AAA domain Bax1-I PF01027.20 KFX88126.1 - 5.6e-51 173.3 27.3 6.4e-51 173.1 27.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SH3_1 PF00018.28 KFX88127.1 - 1.6e-08 34.0 0.1 2.6e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX88127.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX88127.1 - 1.2e-05 24.9 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.9 KFX88127.1 - 1.5 9.0 7.8 0.64 10.3 3.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) ABC2_membrane_2 PF12679.7 KFX88127.1 - 4.8 6.4 11.5 7.5 5.7 11.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Dynactin_p22 PF07426.11 KFX88128.1 - 3.4e-07 30.3 0.1 4.6e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Aa_trans PF01490.18 KFX88129.1 - 1.5e-92 310.5 20.5 2.1e-92 309.9 20.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFX88129.1 - 1.5e-08 34.1 20.0 1.5e-08 34.1 20.0 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family ORMDL PF04061.14 KFX88129.1 - 2.3 8.1 7.0 0.28 11.0 1.4 2.4 2 1 0 2 2 2 0 ORMDL family Ribosomal_S16 PF00886.19 KFX88130.1 - 8.4e-26 89.8 0.1 1.2e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KFX88131.1 - 1.1e-32 113.3 0.0 1.3e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 KFX88131.1 - 0.027 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ras PF00071.22 KFX88132.1 - 1.9e-52 177.1 0.0 2.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX88132.1 - 5.3e-19 68.6 0.0 7.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX88132.1 - 2e-10 40.4 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX88132.1 - 8.5e-06 25.4 0.0 7.2e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX88132.1 - 8.9e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX88132.1 - 0.0015 18.4 0.0 0.69 9.8 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFX88132.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KFX88132.1 - 0.022 15.0 0.2 0.3 11.3 0.1 2.6 1 1 0 2 2 2 0 AAA domain WSC PF01822.19 KFX88134.1 - 2.9e-35 120.3 63.7 3.6e-14 52.7 6.1 5.7 5 0 0 5 5 5 3 WSC domain Glyco_hydro_18 PF00704.28 KFX88134.1 - 1.4e-15 57.8 0.7 3.6e-15 56.5 0.7 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX88134.1 - 2.3e-05 24.4 0.2 5.4e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 LysM domain Glyco_hydro_61 PF03443.14 KFX88137.1 - 2.5e-59 200.6 0.3 3.7e-59 200.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFX88137.1 - 1.1e-05 25.2 2.8 1.1e-05 25.2 2.8 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 KFX88138.1 - 9.9e-49 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL_2 PF13472.6 KFX88140.1 - 2e-07 31.6 4.0 3.7e-07 30.7 4.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX88140.1 - 4.8e-05 23.4 0.0 7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1295 PF06966.12 KFX88141.1 - 3.9e-14 52.7 0.0 6.4e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KFX88141.1 - 6.9e-05 21.8 0.1 9.9e-05 21.3 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.24 KFX88142.1 - 3.2e-109 365.8 19.5 3.7e-109 365.6 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88142.1 - 2.7e-21 75.9 32.3 5.9e-19 68.2 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KFX88142.1 - 1.1 7.5 5.2 1.8 6.7 5.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Hexokinase_2 PF03727.16 KFX88143.1 - 7.4e-46 156.5 0.0 1.1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFX88143.1 - 2.8e-40 138.3 0.0 4.1e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase CK_II_beta PF01214.18 KFX88146.1 - 2.5e-75 252.3 0.0 3.8e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KFX88146.1 - 0.24 9.9 1.8 0.32 9.5 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 KFX88146.1 - 0.25 10.9 5.0 0.075 12.6 1.8 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 KFX88146.1 - 0.88 10.0 8.1 1.9 8.9 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 KFX88146.1 - 3 8.1 7.8 26 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 KFX88146.1 - 4.3 7.0 5.6 2.1 8.0 2.4 1.9 2 0 0 2 2 2 0 FAM176 family Cupin_8 PF13621.6 KFX88147.1 - 1.8e-23 83.6 0.0 2.6e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain FMO-like PF00743.19 KFX88147.1 - 2e-09 36.4 0.2 8.7e-08 31.0 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX88147.1 - 3.2e-07 29.8 0.0 5.4e-06 25.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX88147.1 - 7e-07 29.4 0.1 3.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX88147.1 - 1.4e-05 24.5 0.0 0.05 12.8 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX88147.1 - 3.9e-05 23.0 0.0 0.0042 16.4 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Cupin_2 PF07883.11 KFX88147.1 - 8.6e-05 22.2 0.1 0.00027 20.6 0.0 1.9 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 KFX88147.1 - 0.00013 22.4 0.0 0.0003 21.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFX88147.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_3 PF05899.12 KFX88147.1 - 0.035 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFX88147.1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AraC-like ligand binding domain DOPA_dioxygen PF08883.11 KFX88148.1 - 2e-43 146.9 0.0 2.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family adh_short PF00106.25 KFX88150.1 - 4e-29 101.5 0.1 6.7e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX88150.1 - 3.3e-19 69.4 0.1 5.6e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX88150.1 - 8.5e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFX88150.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KFX88150.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFX88150.1 - 0.066 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KFX88150.1 - 0.12 12.2 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sas10 PF09368.10 KFX88151.1 - 6.3e-29 100.3 7.4 6.3e-29 100.3 7.4 2.5 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFX88151.1 - 6.9e-11 42.6 0.0 6.9e-11 42.6 0.0 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Rox3 PF08633.10 KFX88152.1 - 2.4e-66 223.9 0.2 2.4e-66 223.9 0.2 2.0 2 0 0 2 2 2 1 Rox3 mediator complex subunit RRM_1 PF00076.22 KFX88153.1 - 2.1e-57 190.9 1.9 4e-18 65.0 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.12 KFX88153.1 - 0.0039 17.0 21.4 0.0039 17.0 21.4 3.6 4 1 0 4 4 4 1 Cwf15/Cwc15 cell cycle control protein RRM_5 PF13893.6 KFX88153.1 - 0.0094 15.5 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFX88153.1 - 0.013 15.1 0.1 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 KFX88153.1 - 0.023 14.8 0.0 51 4.1 0.0 3.8 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 KFX88153.1 - 0.056 13.3 0.0 0.66 9.9 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFX88153.1 - 0.059 13.2 0.1 15 5.4 0.0 2.8 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Ribosomal_L1 PF00687.21 KFX88154.1 - 4.2e-45 154.0 0.2 4.8e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Myb_DNA-bind_6 PF13921.6 KFX88155.1 - 0.00011 22.4 0.2 0.0012 19.1 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX88155.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DASH_Spc19 PF08287.11 KFX88155.1 - 0.44 10.4 4.6 1 9.2 4.6 1.6 1 0 0 1 1 1 0 Spc19 WXG100 PF06013.12 KFX88156.1 - 4e-07 30.2 0.2 4.9e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF2388 PF09498.10 KFX88156.1 - 0.0077 16.2 0.1 0.017 15.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) CBS PF00571.28 KFX88158.1 - 7e-15 55.2 1.5 3.7e-06 27.3 0.0 3.7 4 0 0 4 4 4 3 CBS domain Sugar_tr PF00083.24 KFX88159.1 - 9.8e-119 397.2 28.0 1.1e-118 396.9 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88159.1 - 9.9e-19 67.5 40.4 5.5e-13 48.6 23.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KFX88159.1 - 0.42 11.2 5.1 1.3 9.6 5.1 1.8 1 0 0 1 1 1 0 Phage holin family 2 RNA_pol_3_Rpc31 PF11705.8 KFX88163.1 - 3.7e-58 197.5 4.0 3.7e-58 197.5 4.0 1.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KFX88163.1 - 0.11 12.4 2.0 0.097 12.7 2.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSC PF09402.10 KFX88166.1 - 1.6e-60 205.3 0.1 1.9e-60 205.2 0.1 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain tRNA-synt_1b PF00579.25 KFX88167.1 - 1.9e-55 188.3 0.0 2.6e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3455 PF11937.8 KFX88170.1 - 5.3e-35 121.1 0.0 6.7e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) TPR_1 PF00515.28 KFX88171.1 - 1.4e-40 135.5 24.6 1.9e-05 24.2 0.0 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFX88171.1 - 1.4e-38 127.9 24.1 0.00029 20.7 0.1 11.1 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.6 KFX88171.1 - 3.4e-24 84.2 13.3 6.7e-05 22.5 0.0 8.8 6 1 2 8 8 8 7 TPR repeat TPR_8 PF13181.6 KFX88171.1 - 1.5e-20 71.6 19.6 0.012 15.7 0.1 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFX88171.1 - 3.1e-18 66.1 18.6 7.1e-05 23.4 0.3 7.2 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFX88171.1 - 4.9e-16 58.8 28.2 0.0011 19.2 2.7 8.9 6 4 2 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 KFX88171.1 - 1.2e-15 57.4 8.4 1.8e-05 24.8 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX88171.1 - 4.8e-15 55.8 18.3 8e-06 26.3 0.9 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFX88171.1 - 1.7e-14 53.1 11.5 0.2 12.1 0.0 8.6 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX88171.1 - 9e-14 50.4 12.9 0.078 13.0 0.1 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88171.1 - 1e-09 38.4 17.4 0.13 13.1 0.3 8.3 7 2 2 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX88171.1 - 3.8e-08 33.4 12.6 0.028 14.6 0.3 5.5 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KFX88171.1 - 7.2e-08 32.1 22.5 0.024 14.5 0.3 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX88171.1 - 0.00034 19.9 8.9 0.15 11.2 1.3 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFX88171.1 - 0.00083 18.8 16.7 0.9 9.1 0.0 7.2 8 0 0 8 8 8 2 SHNi-TPR DUF3856 PF12968.7 KFX88171.1 - 0.0019 18.3 7.0 2.7 8.1 0.0 5.1 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) DUF3808 PF10300.9 KFX88171.1 - 0.0026 16.5 1.9 0.5 9.0 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) Phage_CP76 PF06892.11 KFX88171.1 - 0.0043 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) TPR_MalT PF17874.1 KFX88171.1 - 0.0056 16.1 4.0 0.013 14.9 1.2 2.7 1 1 0 2 2 2 1 MalT-like TPR region Sel1 PF08238.12 KFX88171.1 - 0.023 15.4 6.5 1.1 10.0 0.1 4.6 5 0 0 5 5 4 0 Sel1 repeat TAF1_subA PF14929.6 KFX88171.1 - 0.031 13.7 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A preATP-grasp_3 PF18301.1 KFX88171.1 - 0.053 13.8 0.9 0.4 11.0 0.3 2.8 2 0 0 2 2 2 0 pre ATP-grasp 3 domain FAT PF02259.23 KFX88171.1 - 0.07 12.3 2.2 2.4 7.3 0.0 2.7 3 0 0 3 3 3 0 FAT domain MIT PF04212.18 KFX88171.1 - 0.22 11.6 13.8 4.9 7.3 0.1 5.7 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain MAS20 PF02064.15 KFX88171.1 - 0.25 11.4 3.0 39 4.4 0.1 4.2 4 1 1 5 5 5 0 MAS20 protein import receptor TPR_6 PF13174.6 KFX88171.1 - 1.1 10.0 20.9 20 6.1 0.5 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFX88171.1 - 6.3 6.9 11.2 6.1 7.0 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Btz PF09405.10 KFX88172.1 - 7.7e-27 94.1 1.7 7.7e-27 94.1 1.7 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding PBP1_TM PF14812.6 KFX88172.1 - 4.9 7.6 6.0 22 5.5 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal N_BRCA1_IG PF16158.5 KFX88173.1 - 3.2e-33 114.5 0.8 1e-32 112.9 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KFX88173.1 - 3e-20 71.8 55.4 6.9e-07 29.0 7.4 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KFX88173.1 - 0.0038 17.5 39.2 0.074 13.4 5.9 4.6 4 0 0 4 4 4 3 C1 domain Zn_ribbon_2 PF12674.7 KFX88173.1 - 0.27 11.9 6.9 5.9 7.6 0.1 3.1 2 0 0 2 2 2 0 Putative zinc ribbon domain NmrA PF05368.13 KFX88174.1 - 6.5e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX88174.1 - 8.7e-20 71.4 0.0 2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KFX88174.1 - 4.5e-06 26.8 0.0 8.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFX88174.1 - 0.01 16.1 0.1 0.041 14.1 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 KFX88174.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 KFX88174.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MBF1 PF08523.10 KFX88175.1 - 2.1e-26 92.2 1.5 3.5e-26 91.5 1.5 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KFX88175.1 - 7.5e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix MRP-L27 PF09809.9 KFX88175.1 - 0.065 13.1 0.2 0.08 12.8 0.2 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 RHH_6 PF16762.5 KFX88182.1 - 0.021 15.4 0.3 0.04 14.5 0.3 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Arrestin_C PF02752.22 KFX88185.1 - 3.6e-08 33.9 0.0 2e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFX88185.1 - 8.4e-08 32.4 0.1 0.0031 17.6 0.0 3.5 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain CDC45 PF02724.14 KFX88185.1 - 0.37 9.0 0.9 3.9 5.7 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein PTCB-BRCT PF12738.7 KFX88186.1 - 5.8e-49 163.9 0.7 8.6e-22 76.9 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KFX88186.1 - 2.9e-35 120.5 0.7 5.6e-14 52.3 0.0 5.4 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFX88186.1 - 2.3e-17 63.1 0.0 1.8e-06 28.2 0.0 4.4 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFX88186.1 - 2.5e-07 30.7 0.1 0.0072 16.4 0.0 4.0 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFX88186.1 - 3.6e-07 30.4 0.1 0.0066 16.7 0.0 4.1 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain LSM PF01423.22 KFX88190.1 - 1.3e-12 47.3 0.0 1.3e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFX88190.1 - 0.0013 18.9 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain HlyD_D23 PF16576.5 KFX88190.1 - 0.083 12.1 0.1 0.086 12.0 0.1 1.0 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Snf7 PF03357.21 KFX88194.1 - 0.0095 15.5 0.2 0.013 15.1 0.1 1.3 1 1 0 1 1 1 1 Snf7 DSHCT PF08148.12 KFX88195.1 - 8.4e-51 171.9 0.6 1.9e-50 170.7 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 KFX88195.1 - 3.8e-23 82.8 0.0 7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain Ras PF00071.22 KFX88198.1 - 6.9e-59 198.1 0.2 8.3e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX88198.1 - 2.1e-19 69.9 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX88198.1 - 3.1e-07 30.0 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX88198.1 - 4.7e-05 23.0 0.1 0.00029 20.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX88198.1 - 0.001 19.0 0.0 1.2 9.0 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX88198.1 - 0.0086 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX88198.1 - 0.029 13.9 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KFX88198.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NAD_binding_1 PF00175.21 KFX88201.1 - 4.1e-15 56.4 0.0 5.9e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFX88201.1 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PEMT PF04191.13 KFX88202.1 - 3.1e-59 197.9 11.1 4.5e-37 126.7 1.9 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 KFX88202.1 - 0.02 14.7 0.1 0.076 12.8 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KFX88202.1 - 0.06 13.9 0.0 0.89 10.1 0.0 2.3 1 1 0 1 1 1 0 SKICH domain ParA PF10609.9 KFX88203.1 - 1.3e-95 319.6 0.0 1.5e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFX88203.1 - 1e-08 35.3 0.0 2.8e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFX88203.1 - 6.8e-05 22.9 0.0 0.0003 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFX88203.1 - 0.00047 19.4 0.5 0.002 17.4 0.3 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 KFX88203.1 - 0.0022 17.8 0.1 0.55 10.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX88203.1 - 0.0048 16.7 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 KFX88203.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KFX88203.1 - 0.01 15.3 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KFX88203.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFX88203.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase CLP1_P PF16575.5 KFX88203.1 - 0.022 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KFX88203.1 - 0.026 14.9 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KFX88203.1 - 0.074 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFX88203.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KFX88203.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX88203.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBP_BcsQ PF06564.12 KFX88203.1 - 0.24 10.9 0.1 1.9 7.9 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Rad17 PF03215.15 KFX88203.1 - 0.25 11.2 0.0 0.47 10.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Ribosomal_L37ae PF01780.19 KFX88206.1 - 0.087 12.9 0.7 0.13 12.4 0.1 1.6 2 0 0 2 2 2 0 Ribosomal L37ae protein family LAMTOR PF15454.6 KFX88207.1 - 1.1e-10 42.0 0.1 1.7e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF713 PF05218.14 KFX88207.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Peptidase_M41 PF01434.18 KFX88222.1 - 6.4e-67 225.1 0.0 1.1e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFX88222.1 - 5.2e-42 143.4 0.0 1.2e-41 142.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX88222.1 - 2.4e-12 46.4 0.1 6.4e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain APH PF01636.23 KFX88222.1 - 9.4e-09 35.5 0.0 9.7e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family FtsH_ext PF06480.15 KFX88222.1 - 6.3e-06 26.5 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KFX88222.1 - 0.00043 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX88222.1 - 0.0044 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX88222.1 - 0.0083 16.5 0.0 0.25 11.7 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX88222.1 - 0.012 15.8 0.0 1.9 8.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFX88222.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 KFX88222.1 - 0.033 14.3 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2635 PF10948.8 KFX88228.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) SNF2_N PF00176.23 KFX88237.1 - 1.2e-36 126.2 0.0 1.9e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFX88237.1 - 3.2e-08 33.8 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PS_Dcarbxylase PF02666.15 KFX88241.1 - 2.9e-55 187.0 0.0 5.4e-55 186.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KFX88241.1 - 1.8e-38 131.0 0.0 4.8e-18 65.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 KFX88241.1 - 0.0041 16.9 0.0 0.083 12.9 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFX88241.1 - 0.0058 16.1 0.1 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFX88241.1 - 0.013 15.9 1.5 0.067 13.7 1.5 2.3 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFX88241.1 - 0.075 12.6 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF3742 PF12553.8 KFX88242.1 - 0.044 13.9 1.5 0.74 9.9 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) Sdh5 PF03937.16 KFX88244.1 - 1.1e-23 83.0 0.1 3.2e-23 81.5 0.1 1.9 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ank_2 PF12796.7 KFX88244.1 - 1.7e-23 83.0 0.5 1.1e-05 26.0 0.0 4.9 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX88244.1 - 4.5e-12 46.2 4.6 4.8e-05 23.8 0.0 6.5 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX88244.1 - 5.3e-11 41.7 2.7 0.027 15.0 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat AAA_16 PF13191.6 KFX88244.1 - 9.2e-08 32.6 0.0 3e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank_5 PF13857.6 KFX88244.1 - 2.6e-07 30.8 1.9 0.77 10.2 0.0 5.8 3 3 3 6 6 6 1 Ankyrin repeats (many copies) NACHT PF05729.12 KFX88244.1 - 3.4e-06 27.1 0.0 7.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KFX88244.1 - 1.2e-05 25.6 3.7 3.6 8.2 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat AAA_22 PF13401.6 KFX88244.1 - 0.00019 21.7 0.0 0.0006 20.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFX88244.1 - 0.12 12.8 0.2 0.45 11.0 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pribosyltran PF00156.27 KFX88251.1 - 2e-14 53.4 0.1 3.1e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_127 PF07944.12 KFX88252.1 - 3e-141 471.5 1.5 3.4e-141 471.3 1.5 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF4986 PF16375.5 KFX88252.1 - 0.027 15.1 0.0 0.065 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function MFS_1 PF07690.16 KFX88253.1 - 1.3e-43 149.3 47.7 2.2e-43 148.5 47.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily HRI1 PF16815.5 KFX88253.1 - 6.5e-29 101.3 0.1 1.8e-28 99.8 0.0 1.7 2 0 0 2 2 2 1 Protein HRI1 Phage_holin_2_2 PF10746.9 KFX88255.1 - 0.074 12.7 0.4 0.27 10.9 0.4 1.9 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II 4HBT_2 PF13279.6 KFX88256.1 - 7e-06 26.5 0.0 8.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Wyosine_form PF08608.12 KFX88257.1 - 7.3e-24 83.9 0.0 1.7e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KFX88257.1 - 1.4e-22 80.8 0.0 5.2e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KFX88257.1 - 9.7e-10 38.8 0.4 4.7e-09 36.6 0.4 2.1 1 1 0 1 1 1 1 Flavodoxin EMC3_TMCO1 PF01956.16 KFX88258.1 - 3.1 7.5 5.3 4.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AA_permease_2 PF13520.6 KFX88259.1 - 4.4e-47 160.9 52.6 5.4e-47 160.6 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX88259.1 - 2e-22 79.4 44.1 2.8e-22 79.0 44.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KFX88260.1 - 3e-15 56.0 53.9 9.7e-10 37.9 26.2 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily adh_short PF00106.25 KFX88261.1 - 3.5e-30 104.9 0.2 4.6e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX88261.1 - 3.2e-23 82.5 0.1 4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX88261.1 - 1.9e-09 37.7 0.5 2.6e-09 37.2 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX88261.1 - 0.00066 19.6 0.4 0.0011 18.9 0.4 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX88261.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3426 PF11906.8 KFX88261.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) RrnaAD PF00398.20 KFX88262.1 - 1.6e-62 211.0 0.0 2.1e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFX88262.1 - 2.1e-07 31.5 0.0 4.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX88262.1 - 3.1e-05 24.5 0.0 7.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX88262.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFX88262.1 - 0.00025 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 KFX88262.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 KFX88262.1 - 0.0064 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX88262.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KFX88262.1 - 0.0093 16.7 0.0 0.027 15.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KFX88262.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFX88262.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_lid_4 PF17864.1 KFX88262.1 - 0.048 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain Ubie_methyltran PF01209.18 KFX88262.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFX88262.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRP1_N PF06424.12 KFX88263.1 - 1.2e-16 61.4 0.8 1.4e-16 61.2 0.8 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal DUF1471 PF07338.13 KFX88263.1 - 0.16 12.0 0.7 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Ribosomal_60s PF00428.19 KFX88263.1 - 0.17 12.5 3.5 0.28 11.8 3.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4772 PF15997.5 KFX88280.1 - 0.097 13.3 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) Peptidase_M28 PF04389.17 KFX88283.1 - 3e-36 125.0 0.1 4.6e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFX88283.1 - 0.00026 20.8 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Chalcone_2 PF16035.5 KFX88284.1 - 2.1e-76 256.3 0.1 3.7e-76 255.5 0.0 1.4 2 0 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 KFX88284.1 - 0.00054 20.1 0.0 0.064 13.4 0.0 2.5 3 0 0 3 3 3 1 Chalcone isomerase-like Chalcone PF02431.15 KFX88284.1 - 0.0065 15.9 0.0 0.066 12.6 0.0 2.0 2 0 0 2 2 2 1 Chalcone-flavanone isomerase Stathmin PF00836.19 KFX88284.1 - 0.22 11.5 0.9 0.37 10.8 0.9 1.3 1 0 0 1 1 1 0 Stathmin family Glutaredoxin PF00462.24 KFX88285.1 - 8.9e-20 70.7 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFX88285.1 - 0.0017 18.8 0.1 0.0045 17.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFX88285.1 - 0.0023 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 KFX88285.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 KFX88285.1 - 0.018 15.0 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 KFX88285.1 - 0.046 13.5 0.2 0.93 9.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 KFX88285.1 - 0.068 13.5 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 KFX88285.1 - 0.11 12.6 1.5 4.7 7.3 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Ribosomal_L13 PF00572.18 KFX88286.1 - 2.3e-10 40.8 0.0 2e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.28 KFX88287.1 - 1.5e-72 244.5 0.1 1.8e-72 244.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX88287.1 - 1.8e-19 70.4 0.1 3.7e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 KFX88287.1 - 0.037 13.4 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain LRR_6 PF13516.6 KFX88288.1 - 1.6e-11 43.3 19.9 5.1 7.4 0.1 11.7 13 0 0 13 13 13 5 Leucine Rich repeat LRR_4 PF12799.7 KFX88288.1 - 2.3e-11 43.7 14.9 0.3 11.6 0.4 7.1 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFX88288.1 - 1.5e-10 40.8 0.4 8.5e-10 38.4 0.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFX88288.1 - 5.8e-06 26.1 0.0 0.00014 21.6 0.0 2.8 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 KFX88288.1 - 0.0057 16.3 1.7 2 8.1 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1699) PMI_typeI PF01238.21 KFX88290.1 - 2.2e-141 471.4 0.0 2.6e-141 471.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Hexapep PF00132.24 KFX88291.1 - 5.2e-08 32.3 8.8 0.00026 20.6 1.8 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX88291.1 - 5.4e-05 22.8 11.1 0.00024 20.8 0.4 4.0 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFX88291.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Actin PF00022.19 KFX88293.1 - 1.2e-111 373.2 0.0 5.4e-111 371.1 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFX88293.1 - 0.0044 15.9 0.0 0.015 14.1 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Sugar_tr PF00083.24 KFX88294.1 - 1.4e-84 284.5 24.7 4.8e-83 279.5 24.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88294.1 - 6.1e-30 104.3 44.3 8.8e-29 100.5 36.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFX88294.1 - 0.0005 19.5 9.3 0.0005 19.5 9.3 3.1 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 KFX88295.1 - 1.7e-64 217.7 0.0 2.4e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88295.1 - 1.8e-29 102.8 0.0 3.9e-29 101.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX88295.1 - 0.037 13.0 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFX88295.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KFX88295.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_67M PF07488.12 KFX88296.1 - 7.7e-146 485.3 0.1 1.4e-145 484.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KFX88296.1 - 3.2e-89 298.3 4.6 4.6e-89 297.8 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KFX88296.1 - 8.2e-30 103.6 0.0 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KFX88296.1 - 0.0012 19.6 0.0 0.0039 18.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MCM_lid PF17855.1 KFX88298.1 - 1.1e-23 83.4 1.5 1.1e-23 83.4 1.5 1.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM PF00493.23 KFX88298.1 - 3.5e-14 52.5 0.0 5.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_32 PF13654.6 KFX88298.1 - 0.15 10.8 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KFX88299.1 - 2.6e-110 361.2 13.2 1.1e-17 64.3 0.3 8.2 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 KFX88299.1 - 1.6e-73 240.1 9.9 1.5e-06 28.3 0.0 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 KFX88299.1 - 4.4e-69 220.2 3.6 0.00011 22.3 0.0 14.0 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.6 KFX88299.1 - 6.2e-55 182.9 4.4 3e-09 37.2 0.0 9.4 6 3 3 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX88299.1 - 4.5e-46 154.3 12.8 6.7e-06 26.3 0.0 11.4 2 2 10 12 12 12 12 Ankyrin repeats (many copies) NACHT PF05729.12 KFX88299.1 - 1.5e-08 34.7 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX88299.1 - 6.5e-05 23.4 0.1 0.00042 20.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX88299.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KFX88300.1 - 1.5e-74 249.3 0.2 1.7e-74 249.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFX88300.1 - 4.3e-15 56.0 0.1 5.8e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFX88300.1 - 2.5e-13 49.9 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFX88300.1 - 3.5e-12 46.1 2.0 3e-08 33.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFX88300.1 - 1.1e-11 44.6 0.1 1.3e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFX88300.1 - 3.6e-10 39.6 0.1 4.5e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX88300.1 - 9.4e-05 22.5 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFX88300.1 - 0.031 13.6 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DEAD PF00270.29 KFX88310.1 - 3e-47 160.6 0.1 3e-46 157.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX88310.1 - 2.4e-24 85.8 0.0 6.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFX88310.1 - 4.7e-19 68.4 0.2 8.8e-19 67.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFX88310.1 - 5.3e-06 26.6 0.0 9.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFX88310.1 - 2.5e-05 23.6 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_25 PF13481.6 KFX88310.1 - 0.017 14.7 0.1 0.17 11.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain SecA_DEAD PF07517.14 KFX88310.1 - 0.12 11.6 0.0 0.39 10.0 0.0 1.7 2 1 0 2 2 2 0 SecA DEAD-like domain 2OG-FeII_Oxy_2 PF13532.6 KFX88311.1 - 0.0041 17.3 0.0 0.013 15.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.21 KFX88312.1 - 2.1e-47 161.3 0.1 3.2e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KFX88312.1 - 2.2e-05 24.2 3.9 0.001 19.0 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX88312.1 - 0.006 16.4 3.3 0.0092 15.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX88312.1 - 0.13 12.5 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88312.1 - 2.5 9.2 5.5 3.5 8.7 3.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFX88315.1 - 9e-21 74.2 24.5 3e-15 56.0 23.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribonucleas_3_3 PF14622.6 KFX88316.1 - 3.1e-06 27.4 0.0 5.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFX88316.1 - 5.8e-06 26.9 0.0 2e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain HA2 PF04408.23 KFX88319.1 - 1e-22 80.4 0.0 3.4e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX88319.1 - 3.4e-22 78.6 0.0 6.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX88319.1 - 7.3e-14 52.1 0.0 2.1e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KFX88319.1 - 6.4e-10 39.2 1.2 1.4e-09 38.2 1.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KFX88319.1 - 1.8e-06 27.9 0.4 4.2e-06 26.6 0.4 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX88319.1 - 3e-06 27.5 0.1 7.9e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX88319.1 - 0.00016 21.5 0.1 0.00044 20.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFX88319.1 - 0.00049 19.2 0.2 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFX88319.1 - 0.0013 19.1 0.1 0.0027 18.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFX88319.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KFX88319.1 - 0.068 13.2 0.3 0.63 10.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFX88319.1 - 0.089 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFX88319.1 - 0.11 12.6 0.1 0.39 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KFX88319.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cellulase PF00150.18 KFX88320.1 - 3.5e-16 59.5 4.0 4.6e-16 59.1 4.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KFX88320.1 - 8e-09 35.6 2.6 1.1e-08 35.1 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KFX88320.1 - 2.4e-07 30.2 0.1 5.1e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KFX88320.1 - 0.003 17.0 0.2 0.0061 15.9 0.2 1.4 1 0 0 1 1 1 1 Beta-galactosidase ARID PF01388.21 KFX88323.1 - 1.5e-20 73.6 0.1 1.5e-20 73.6 0.1 2.9 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KFX88323.1 - 0.02 14.2 0.2 0.02 14.2 0.2 2.0 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa GAF_2 PF13185.6 KFX88327.1 - 5.7e-09 36.4 0.0 7.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KFX88327.1 - 1e-05 26.2 0.2 4.9e-05 24.0 0.1 1.8 1 1 0 2 2 2 1 GAF domain DLH PF01738.18 KFX88328.1 - 3.9e-23 82.1 0.0 2.1e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KFX88328.1 - 0.031 13.7 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family EphA2_TM PF14575.6 KFX88329.1 - 0.0038 18.1 0.0 0.016 16.1 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 KFX88329.1 - 0.0075 16.2 0.7 0.016 15.1 0.7 1.5 1 0 0 1 1 1 1 DAP10 membrane protein Herpes_gE PF02480.16 KFX88329.1 - 0.027 13.3 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcmD PF04995.14 KFX88329.1 - 0.042 13.9 0.8 0.069 13.2 0.8 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Amnionless PF14828.6 KFX88329.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 KFX88329.1 - 1.8 8.5 9.8 14 5.6 9.8 2.3 1 1 0 1 1 1 0 TMEM154 protein family Lipase_GDSL_2 PF13472.6 KFX88331.1 - 0.00083 19.8 0.0 0.0013 19.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box PF00646.33 KFX88332.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 F-box domain ERG4_ERG24 PF01222.17 KFX88333.1 - 3.1e-167 556.7 6.0 3.7e-167 556.5 6.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFX88333.1 - 0.00068 19.2 1.2 0.001 18.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Abhydrolase_1 PF00561.20 KFX88347.1 - 7.6e-09 35.6 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX88347.1 - 1e-07 32.8 0.0 1.4e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX88347.1 - 3e-05 23.4 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAP2 PF01569.21 KFX88350.1 - 4e-25 88.1 5.2 4e-25 88.1 5.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF983 PF06170.12 KFX88350.1 - 2.4 8.6 6.1 21 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Transglut_core2 PF13369.6 KFX88351.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ribosomal_L5e PF17144.4 KFX88354.1 - 1.6e-79 265.6 0.1 1.6e-79 265.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFX88354.1 - 2.6e-32 111.6 10.9 2.6e-32 111.6 10.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KFX88355.1 - 0.00031 20.9 0.0 0.00064 19.8 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GATase PF00117.28 KFX88356.1 - 2.6e-08 33.9 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I baeRF_family3 PF18845.1 KFX88356.1 - 0.38 11.0 3.9 0.66 10.2 3.9 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 CT47 PF15623.6 KFX88356.1 - 1.9 8.3 15.3 2.6 7.8 15.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Sugar_tr PF00083.24 KFX88358.1 - 2.3e-109 366.3 18.9 2.8e-109 366.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88358.1 - 9.3e-31 107.0 31.0 9.3e-30 103.7 22.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KFX88358.1 - 0.00051 19.1 0.2 0.0011 17.9 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Trp_oprn_chp PF09534.10 KFX88358.1 - 0.1 12.4 1.6 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM132D_C PF15706.5 KFX88358.1 - 0.95 9.3 2.7 3.4 7.5 0.6 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Methyltransf_25 PF13649.6 KFX88359.1 - 4.5e-17 62.6 0.0 7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX88359.1 - 1.5e-12 47.6 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX88359.1 - 1.1e-11 45.2 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX88359.1 - 2.2e-10 40.6 0.0 2.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX88359.1 - 1.7e-07 30.8 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX88359.1 - 2.6e-07 31.3 0.0 4.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFX88359.1 - 0.00015 20.8 0.0 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 KFX88359.1 - 0.00085 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.13 KFX88359.1 - 0.0039 16.6 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KFX88359.1 - 0.0074 15.9 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 KFX88359.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 KFX88359.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_C2 PF00648.21 KFX88360.1 - 5.4e-63 212.8 0.3 2.4e-61 207.4 0.3 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease DUF3543 PF12063.8 KFX88363.1 - 9.4e-92 306.9 0.5 2.1e-91 305.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KFX88363.1 - 1.2e-60 205.1 0.0 2.7e-60 204.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88363.1 - 1.3e-42 145.9 0.0 2.5e-42 145.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFX88363.1 - 0.18 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.16 KFX88364.1 - 8.3e-31 107.2 28.2 8.3e-31 107.2 28.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3405 PF11885.8 KFX88365.1 - 4.3e-150 500.7 0.0 5.3e-150 500.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Transp_cyt_pur PF02133.15 KFX88366.1 - 2.7e-147 491.1 34.7 3.2e-147 490.9 34.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MerB PF03243.15 KFX88368.1 - 0.0086 16.2 1.9 6 7.0 0.1 3.3 3 0 0 3 3 3 2 Alkylmercury lyase DUF3400 PF11880.8 KFX88368.1 - 0.049 13.2 0.7 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) Zn_clus PF00172.18 KFX88369.1 - 9.4e-08 32.1 14.6 9.4e-08 32.1 14.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX88369.1 - 1.8e-07 30.4 1.0 6.1e-07 28.6 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Erf4 PF10256.9 KFX88370.1 - 0.0036 17.4 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RR_TM4-6 PF06459.12 KFX88370.1 - 1.6 8.5 12.1 2.4 7.9 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KFX88370.1 - 5.2 5.2 13.7 6.8 4.9 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 KFX88370.1 - 9.1 5.5 9.0 13 4.9 9.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Glyco_hydro_20 PF00728.22 KFX88371.1 - 2.4e-83 280.4 0.0 3e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFX88371.1 - 2.4e-24 86.5 0.0 4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFX88371.1 - 1.2e-05 26.0 0.0 2.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_transf_22 PF03901.17 KFX88372.1 - 9.7e-81 272.1 20.4 1.3e-80 271.7 20.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Imm17 PF15562.6 KFX88372.1 - 0.062 13.2 0.3 4.8 7.1 0.2 3.5 3 0 0 3 3 3 0 Immunity protein 17 Aminotran_3 PF00202.21 KFX88373.1 - 2.6e-118 395.2 0.0 3e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFX88373.1 - 0.00022 20.5 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFX88373.1 - 0.00051 19.4 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase OAM_dimer PF16554.5 KFX88373.1 - 0.042 14.3 0.0 0.095 13.2 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase zf-TRAF PF02176.18 KFX88377.1 - 7.8e-10 39.3 19.6 6.7e-05 23.5 5.9 3.7 2 1 2 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFX88377.1 - 1.3e-08 34.6 5.7 1.3e-08 34.6 5.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX88377.1 - 5.6e-07 29.4 3.9 5.6e-07 29.4 3.9 2.9 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX88377.1 - 1.1e-06 28.5 7.7 1.1e-06 28.5 7.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFX88377.1 - 2e-06 28.0 5.2 2e-06 28.0 5.2 3.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFX88377.1 - 2.1e-06 27.5 5.2 2.1e-06 27.5 5.2 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX88377.1 - 1.5e-05 24.7 3.6 1.5e-05 24.7 3.6 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KFX88377.1 - 3.4e-05 24.2 17.4 0.0058 17.1 6.3 2.9 2 1 0 2 2 2 2 TRAF-like zinc-finger Prok-RING_4 PF14447.6 KFX88377.1 - 4.9e-05 23.1 6.0 4.9e-05 23.1 6.0 3.3 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFX88377.1 - 7.3e-05 22.8 7.0 7.3e-05 22.8 7.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFX88377.1 - 0.00059 19.9 3.1 0.00059 19.9 3.1 2.5 2 1 0 2 2 1 1 zinc RING finger of MSL2 Sina PF03145.16 KFX88377.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.8 2 1 0 2 2 2 0 Seven in absentia protein family zf-Nse PF11789.8 KFX88377.1 - 0.43 10.4 11.7 3.7 7.4 11.7 2.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FTR1 PF03239.14 KFX88380.1 - 7.7e-82 274.9 6.9 9.5e-82 274.6 6.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family GPI2 PF06432.11 KFX88380.1 - 0.01 15.3 1.0 0.053 13.0 0.3 2.2 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2854 PF11016.8 KFX88383.1 - 0.17 11.8 0.3 0.32 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Apolipoprotein PF01442.18 KFX88384.1 - 6.3e-09 36.0 10.0 4.8e-07 29.8 6.9 3.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain MHCassoc_trimer PF08831.10 KFX88384.1 - 6.3e-05 22.9 0.2 0.0091 16.0 0.0 3.0 2 1 1 3 3 3 1 Class II MHC-associated invariant chain trimerisation domain Gp-FAR-1 PF05823.12 KFX88384.1 - 0.00019 21.8 17.9 0.063 13.6 0.0 3.8 2 1 0 3 3 3 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 KFX88384.1 - 0.0049 17.0 19.5 0.064 13.3 2.0 4.3 1 1 2 4 4 4 2 Apolipophorin-III precursor (apoLp-III) HTH_48 PF17906.1 KFX88384.1 - 0.0058 16.7 0.7 2.3 8.4 0.0 3.8 4 0 0 4 4 4 1 HTH domain in Mos1 transposase Globin PF00042.22 KFX88384.1 - 0.023 15.2 1.2 2 9.0 0.1 3.2 2 1 0 3 3 3 0 Globin DUF883 PF05957.13 KFX88384.1 - 0.054 14.1 8.5 2.9 8.6 0.0 4.6 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Peptidase_M41 PF01434.18 KFX88384.1 - 0.15 11.9 6.3 0.15 11.8 0.6 3.1 1 1 0 2 2 2 0 Peptidase family M41 DUF2523 PF10734.9 KFX88384.1 - 0.17 12.5 0.0 0.61 10.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Prominin PF05478.11 KFX88384.1 - 0.21 9.5 5.5 4.2 5.2 0.3 2.5 1 1 0 2 2 2 0 Prominin DHC PF09626.10 KFX88384.1 - 0.27 12.1 2.3 36 5.2 0.1 3.2 3 1 0 3 3 3 0 Dihaem cytochrome c FAM25 PF15825.5 KFX88384.1 - 0.37 11.2 13.8 0.64 10.4 0.5 3.8 3 1 0 3 3 3 0 FAM25 family ApoL PF05461.11 KFX88384.1 - 0.51 9.6 5.3 3 7.1 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein L Fib_alpha PF08702.10 KFX88384.1 - 1.1 9.4 8.5 16 5.7 0.1 3.7 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF885 PF05960.11 KFX88384.1 - 1.3 8.6 6.5 3.5 7.1 6.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CarD_CdnL_TRCF PF02559.16 KFX88384.1 - 6.6 7.5 11.7 25 5.7 2.8 4.2 1 1 2 3 3 3 0 CarD-like/TRCF domain DUF1687 PF07955.11 KFX88384.1 - 9.6 6.7 7.0 16 6.0 1.0 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1687) Paf1 PF03985.13 KFX88386.1 - 0.55 9.2 12.2 0.68 8.9 12.2 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 KFX88386.1 - 2.6 6.1 18.9 3 5.9 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFX88386.1 - 4.4 6.6 19.2 5 6.4 19.2 1.1 1 0 0 1 1 1 0 BUD22 Aminotran_4 PF01063.19 KFX88387.1 - 1.6e-34 119.7 0.0 2.1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV FGGY_C PF02782.16 KFX88388.1 - 4.6e-26 91.8 0.0 7.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX88388.1 - 1.5e-23 83.6 0.0 1.5e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AhpC-TSA_2 PF13911.6 KFX88390.1 - 7.1e-08 32.6 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFX88390.1 - 2.9e-05 24.0 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family TFIIB PF00382.19 KFX88392.1 - 3.7e-33 113.4 0.0 7.2e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFX88392.1 - 8.4e-14 50.8 1.5 1.4e-13 50.1 1.5 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 KFX88392.1 - 0.0052 16.9 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 KFX88392.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 zf-ribbon_3 PF13248.6 KFX88392.1 - 0.044 13.2 0.5 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.9 KFX88393.1 - 9.2e-27 92.8 1.4 1.3e-26 92.4 1.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Cu-oxidase_3 PF07732.15 KFX88397.1 - 8e-38 129.1 0.6 2e-37 127.9 0.3 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX88397.1 - 1.8e-37 128.9 0.6 1e-34 119.9 0.3 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX88397.1 - 0.0026 17.5 0.3 0.042 13.6 0.3 2.5 1 1 0 1 1 1 1 Multicopper oxidase Rax2 PF12768.7 KFX88400.1 - 3.6e-78 261.9 0.7 3.2e-77 258.8 0.0 2.9 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 KFX88400.1 - 0.0063 16.8 11.8 0.17 12.2 0.1 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF5122) beta-propeller Kelch_4 PF13418.6 KFX88400.1 - 0.053 13.5 3.6 0.12 12.4 0.3 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain SNase PF00565.17 KFX88401.1 - 2.4e-23 82.7 0.2 3.6e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.14 KFX88402.1 - 7.3e-107 356.5 0.3 8.9e-107 356.3 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFX88402.1 - 0.02 14.5 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.21 KFX88402.1 - 0.18 12.2 1.5 2.9 8.2 0.4 2.3 1 1 1 2 2 2 0 Radical SAM superfamily WD40 PF00400.32 KFX88403.1 - 2.1e-48 161.3 25.4 3.5e-06 27.7 0.1 12.3 12 1 0 12 12 12 10 WD domain, G-beta repeat APH PF01636.23 KFX88403.1 - 5.3e-40 137.8 0.0 9.9e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Utp12 PF04003.12 KFX88403.1 - 8.9e-20 71.0 1.2 1.8e-19 70.0 1.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFX88403.1 - 9.3e-20 70.7 5.4 0.012 15.9 0.0 9.3 5 4 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX88403.1 - 8.4e-07 28.3 1.2 1.3 7.9 0.0 5.5 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX88403.1 - 0.0012 18.3 0.0 2.3 7.4 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain RIO1 PF01163.22 KFX88403.1 - 0.0047 16.5 0.0 0.046 13.3 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Nup160 PF11715.8 KFX88403.1 - 0.0065 15.2 3.8 0.28 9.8 0.0 4.4 5 1 1 6 6 6 1 Nucleoporin Nup120/160 EcKinase PF02958.20 KFX88403.1 - 0.0098 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KFX88403.1 - 0.011 15.1 0.1 0.07 12.5 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleoporin_N PF08801.11 KFX88403.1 - 0.042 12.6 0.2 3.4 6.3 0.0 3.5 3 1 0 3 3 3 0 Nup133 N terminal like DUF1679 PF07914.11 KFX88403.1 - 0.086 11.7 0.0 0.26 10.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) eIF2A PF08662.11 KFX88403.1 - 0.091 12.6 0.0 0.99 9.3 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A GTP_EFTU PF00009.27 KFX88405.1 - 5e-07 29.4 0.0 1.4e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFX88405.1 - 0.07 13.5 0.1 0.22 11.9 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Rab5ip PF07019.12 KFX88406.1 - 1e-20 74.1 3.2 1.3e-20 73.8 3.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) BCLP PF12304.8 KFX88406.1 - 0.04 13.5 0.9 2.6 7.6 0.1 2.1 2 0 0 2 2 2 0 Beta-casein like protein Vezatin PF12632.7 KFX88408.1 - 1.7e-80 270.4 0.0 3.7e-80 269.3 0.0 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KFX88408.1 - 1.4e-55 186.4 3.8 3.4e-55 185.2 3.8 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KFX88408.1 - 5.7e-48 162.3 0.0 1.4e-47 161.0 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KFX88408.1 - 1.6e-07 31.0 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KFX88408.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.16 KFX88408.1 - 0.0024 17.0 0.6 0.054 12.5 0.6 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF1480 PF07351.13 KFX88408.1 - 0.059 13.7 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) AMA-1 PF02430.15 KFX88408.1 - 0.15 11.0 2.0 1.2 8.0 0.0 2.7 3 0 0 3 3 3 0 Apical membrane antigen 1 Amastin PF07344.11 KFX88408.1 - 0.19 11.6 0.6 0.39 10.6 0.6 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein Phos_pyr_kin PF08543.12 KFX88409.1 - 2.8e-13 49.8 0.0 5.3e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFX88409.1 - 2.5e-06 27.0 0.1 1.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase dUTPase PF00692.19 KFX88410.1 - 1.8e-44 150.5 0.0 2.3e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KFX88410.1 - 0.049 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MARVEL PF01284.23 KFX88411.1 - 6.9e-06 26.1 19.0 9.2e-06 25.7 19.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Rit1_C PF17184.4 KFX88412.1 - 3.2e-108 361.3 0.0 4.3e-108 360.9 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KFX88412.1 - 6.8e-35 119.7 0.0 1.7e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain AF-4 PF05110.13 KFX88413.1 - 0.31 9.1 6.6 0.41 8.7 6.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Serglycin PF04360.12 KFX88413.1 - 3.2 7.7 6.4 5.8 6.9 5.9 1.6 1 1 0 1 1 1 0 Serglycin Aldolase_II PF00596.21 KFX88414.1 - 6.8e-45 153.3 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 KFX88415.1 - 1e-167 557.6 17.8 1.5e-167 557.1 17.8 1.2 1 0 0 1 1 1 1 Calreticulin family adh_short PF00106.25 KFX88418.1 - 1.7e-05 24.4 0.0 0.00037 20.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX88418.1 - 3.8e-05 23.4 0.0 5.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acyl-CoA_dh_1 PF00441.24 KFX88420.1 - 3.9e-36 124.5 0.1 5.8e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX88420.1 - 1.5e-18 66.8 0.2 2.8e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX88420.1 - 2.6e-10 40.9 0.0 1.5e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFX88420.1 - 5e-10 39.8 0.0 8.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.11 KFX88420.1 - 1.1e-08 35.0 9.8 2e-08 34.2 9.8 1.5 1 0 0 1 1 1 1 CFEM domain HpaB_N PF11794.8 KFX88420.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MGC-24 PF05283.11 KFX88420.1 - 0.0032 17.9 1.5 0.0074 16.7 1.5 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KFX88420.1 - 0.017 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.16 KFX88420.1 - 0.045 12.5 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DNA_pol_B PF00136.21 KFX88422.1 - 1.3e-148 495.5 2.1 1.9e-148 495.0 2.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFX88422.1 - 7e-78 262.1 0.2 1.4e-77 261.1 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFX88422.1 - 7.9e-18 64.7 7.1 1.9e-17 63.5 7.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KFX88422.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFX88422.1 - 0.0057 16.7 0.3 0.07 13.1 0.3 2.7 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 KFX88422.1 - 0.033 13.1 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.22 KFX88422.1 - 0.36 10.7 10.2 0.54 10.2 1.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rhomboid PF01694.22 KFX88423.1 - 1.3e-32 112.9 10.3 1.3e-32 112.9 10.3 1.8 2 0 0 2 2 2 1 Rhomboid family Babuvirus_MP PF07234.11 KFX88423.1 - 0.73 10.0 2.2 2.4 8.4 0.6 2.4 2 0 0 2 2 2 0 Movement and RNA silencing protein DUF4381 PF14316.6 KFX88423.1 - 1.1 9.5 4.5 2.3 8.5 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1479 PF07350.12 KFX88426.1 - 1.1e-48 166.0 0.1 1.3e-48 165.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_28 PF03033.20 KFX88427.1 - 8.9e-17 61.4 0.0 2.7e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFX88427.1 - 2.8e-06 26.4 0.0 4.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX88427.1 - 0.00071 19.6 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 KFX88427.1 - 0.025 14.4 0.1 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KFX88427.1 - 0.12 12.8 0.4 0.94 9.9 0.0 2.7 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain Filament PF00038.21 KFX88428.1 - 0.00078 19.1 8.7 0.00078 19.1 8.7 3.4 1 1 2 3 3 3 2 Intermediate filament protein Tropomyosin PF00261.20 KFX88428.1 - 0.0053 16.2 5.2 0.0053 16.2 5.2 4.5 2 2 3 5 5 5 1 Tropomyosin TMF_TATA_bd PF12325.8 KFX88428.1 - 0.0055 16.9 4.4 0.0055 16.9 4.4 4.3 2 2 2 4 4 4 2 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 KFX88428.1 - 0.017 15.3 5.3 0.017 15.3 5.3 3.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 KFX88428.1 - 0.031 14.3 29.3 0.061 13.4 3.3 4.3 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Bacillus_HBL PF05791.11 KFX88428.1 - 0.85 9.4 14.1 0.19 11.6 5.4 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 KFX88428.1 - 4.1 7.5 41.3 0.9 9.6 4.8 3.8 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 KFX88428.1 - 5.9 6.2 36.5 0.34 10.2 18.0 3.7 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 KFX88428.1 - 8.4 6.9 7.0 76 3.9 0.3 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Forkhead PF00250.18 KFX88429.1 - 4.5e-24 84.5 0.1 8.4e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFX88429.1 - 0.00016 22.0 0.0 0.00054 20.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain zf-C2H2 PF00096.26 KFX88430.1 - 3.2e-09 36.7 9.4 0.0042 17.5 0.2 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KFX88430.1 - 0.00016 22.4 2.6 0.00051 20.7 2.6 2.0 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 KFX88430.1 - 0.00024 21.6 13.4 0.25 12.3 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFX88430.1 - 0.01 16.2 11.2 0.25 11.8 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 KFX88430.1 - 0.11 12.3 1.5 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KFX88430.1 - 0.15 11.8 6.9 0.15 11.8 0.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFX88430.1 - 0.19 11.8 3.5 0.44 10.6 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 KFX88430.1 - 0.32 11.8 3.2 1.2 10.0 3.2 2.1 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 KFX88430.1 - 1.8 8.9 14.2 2.7 8.4 1.3 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GATA PF00320.27 KFX88430.1 - 3.4 7.4 5.7 10 5.8 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger zf_C2H2_ZHX PF18387.1 KFX88430.1 - 3.9 7.2 8.6 0.13 11.9 0.8 2.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KFX88430.1 - 4.5 7.7 12.1 15 6.0 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HeLo PF14479.6 KFX88431.1 - 2.8e-39 135.1 0.7 2.8e-39 135.1 0.7 3.3 2 1 0 2 2 2 1 Prion-inhibition and propagation CH PF00307.31 KFX88431.1 - 3.7e-11 43.2 0.0 7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase PF00069.25 KFX88431.1 - 0.00026 20.5 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88431.1 - 0.0015 17.9 0.2 0.017 14.4 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase CAMSAP_CH PF11971.8 KFX88431.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain NDUFA12 PF05071.16 KFX88432.1 - 1.9e-12 47.9 0.1 4.6e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hemopexin PF00045.19 KFX88432.1 - 0.1 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Hemopexin Pkinase PF00069.25 KFX88433.1 - 2.3e-74 250.1 0.0 3.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88433.1 - 7.5e-39 133.6 0.0 1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFX88433.1 - 9.6e-22 77.6 0.0 2e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KFX88433.1 - 2.6e-15 56.2 0.1 6.4e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KFX88433.1 - 2.3e-06 27.1 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFX88433.1 - 0.00022 20.9 0.3 0.00039 20.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFX88433.1 - 0.0009 18.3 0.2 0.0018 17.3 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KFX88433.1 - 0.016 14.1 0.2 0.025 13.4 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 KFX88433.1 - 0.019 14.3 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX88433.1 - 0.15 12.0 0.6 0.57 10.1 0.1 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family CFEM PF05730.11 KFX88437.1 - 0.00036 20.6 1.3 0.00036 20.6 1.3 2.2 2 0 0 2 2 2 1 CFEM domain FHA PF00498.26 KFX88439.1 - 1.1e-12 48.1 0.1 2.9e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFX88439.1 - 0.0067 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SOTI PF17079.5 KFX88439.1 - 3.1 8.3 4.5 1.9 9.0 0.2 2.5 3 0 0 3 3 3 0 Male-specific protein scotti IFRD PF05004.13 KFX88440.1 - 1.1e-83 280.9 8.8 1.4e-83 280.5 8.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KFX88440.1 - 0.00044 20.6 2.1 0.14 12.5 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats FAA_hydro_N_2 PF18288.1 KFX88440.1 - 0.17 12.3 1.8 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 RAP1 PF07218.11 KFX88440.1 - 0.43 8.8 4.4 0.62 8.3 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF-5_eIF-2B PF01873.17 KFX88442.1 - 4.7e-42 142.6 0.3 7.1e-42 142.0 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KFX88442.1 - 0.09 12.3 0.7 0.19 11.3 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.12 KFX88442.1 - 0.39 10.5 5.1 14 5.5 4.7 2.7 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 KFX88442.1 - 1.9 8.9 6.8 1.8 9.0 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain GET2 PF08690.10 KFX88442.1 - 2.4 7.8 6.4 3.7 7.2 6.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Gln-synt_C PF00120.24 KFX88446.1 - 1.2e-17 63.9 0.0 1.1e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFX88446.1 - 5e-14 51.8 0.0 7.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fungal_trans PF04082.18 KFX88449.1 - 1.4e-12 47.3 0.2 2.5e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88449.1 - 7.6e-07 29.2 9.7 1.7e-06 28.0 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KFX88450.1 - 1e-81 273.4 49.9 1.7e-47 161.5 19.0 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFX88450.1 - 2.3e-34 118.8 0.2 1.1e-16 61.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KFX88450.1 - 7.9e-28 96.2 4.8 1.5e-25 88.9 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KFX88450.1 - 1.3e-07 31.1 39.6 4.6e-06 26.0 17.7 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KFX88450.1 - 0.00011 22.7 0.1 0.47 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KFX88450.1 - 0.00013 22.5 0.2 0.00057 20.4 0.2 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KFX88450.1 - 0.00018 21.5 0.2 0.00093 19.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KFX88450.1 - 0.0004 20.6 0.1 0.71 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFX88450.1 - 0.00063 19.6 0.3 0.52 10.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DnaB_C PF03796.15 KFX88450.1 - 0.00095 18.6 0.1 0.079 12.3 0.0 2.4 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KFX88450.1 - 0.003 17.8 0.1 0.43 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX88450.1 - 0.0034 17.0 0.0 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFX88450.1 - 0.005 16.4 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFX88450.1 - 0.0052 16.5 2.7 0.081 12.7 0.2 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA PF00004.29 KFX88450.1 - 0.011 16.2 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFX88450.1 - 0.013 15.9 0.1 4.6 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFX88450.1 - 0.025 15.1 0.0 2.7 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX88450.1 - 0.036 14.0 0.3 5.4 6.9 0.2 2.6 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KFX88450.1 - 0.043 13.7 0.0 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KFX88450.1 - 0.13 12.5 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX88450.1 - 0.15 11.7 1.5 5.7 6.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain MIF4G PF02854.19 KFX88451.1 - 8.6e-51 172.6 0.0 1.5e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFX88451.1 - 2.7e-23 81.9 1.4 8e-23 80.4 1.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Aquarius_N PF16399.5 KFX88452.1 - 0 1131.7 0.0 0 1131.3 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFX88452.1 - 1.5e-26 93.3 0.0 2.8e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX88452.1 - 5.7e-23 82.0 0.0 1.6e-22 80.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX88452.1 - 2.6e-08 33.8 0.0 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFX88452.1 - 5.9e-06 26.7 0.0 1.3e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KFX88452.1 - 9.8e-06 25.7 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFX88452.1 - 0.00012 21.9 0.7 0.008 15.9 0.1 3.4 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KFX88452.1 - 0.00084 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KFX88452.1 - 0.0018 18.7 0.0 0.0091 16.4 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFX88452.1 - 0.0021 18.5 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KFX88452.1 - 0.0023 17.7 0.2 0.0072 16.1 0.2 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KFX88452.1 - 0.014 14.7 1.1 0.023 14.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFX88452.1 - 0.014 15.7 0.2 0.11 12.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX88452.1 - 0.04 13.1 0.0 0.095 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KFX88452.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KFX88452.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 KFX88452.1 - 0.16 11.8 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Helicase DEAD PF00270.29 KFX88452.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase efThoc1 PF11957.8 KFX88453.1 - 7e-148 493.3 0.0 1.2e-147 492.6 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KFX88453.1 - 1e-46 158.9 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KFX88453.1 - 0.00017 22.2 0.1 0.00072 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX88453.1 - 0.011 15.9 0.0 0.05 13.7 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX88453.1 - 0.032 14.2 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase FMO-like PF00743.19 KFX88454.1 - 2.7e-13 49.2 0.0 3.4e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX88454.1 - 2.4e-12 46.7 0.0 5.5e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX88454.1 - 1.2e-10 41.2 0.0 2.2e-09 37.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88454.1 - 5.7e-09 36.1 0.0 1.5e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX88454.1 - 6.5e-08 32.1 0.1 1.4e-06 27.8 0.0 2.4 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 KFX88454.1 - 7.8e-05 22.4 0.2 0.0029 17.3 0.2 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFX88454.1 - 0.0003 20.0 0.0 0.031 13.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFX88454.1 - 0.00093 19.7 0.1 0.25 12.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX88454.1 - 0.016 15.2 0.6 5.2 7.0 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFX88454.1 - 0.025 13.6 0.1 0.58 9.1 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX88454.1 - 0.03 13.4 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KFX88454.1 - 0.087 11.9 0.6 0.52 9.3 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFX88454.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX88454.1 - 0.2 10.3 0.3 0.43 9.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.22 KFX88455.1 - 1.6e-50 172.2 0.0 2.4e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KFX88456.1 - 9.2e-20 71.2 0.4 4.2e-19 69.0 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFX88456.1 - 7.8e-09 35.1 0.3 1.4e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX88456.1 - 8.4e-08 31.8 0.7 3.3e-07 29.8 0.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88456.1 - 1.4e-07 31.7 0.1 3.5e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX88456.1 - 5.2e-06 26.3 0.2 3.7e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX88456.1 - 1.4e-05 25.6 0.8 0.00012 22.6 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX88456.1 - 2.7e-05 23.4 0.1 3.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFX88456.1 - 2.9e-05 23.0 0.3 4.3e-05 22.4 0.3 1.4 1 1 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX88456.1 - 0.00014 21.2 0.2 0.00037 19.8 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KFX88456.1 - 0.0007 19.0 0.7 0.0021 17.4 0.1 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX88456.1 - 0.00074 18.9 0.0 0.0018 17.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX88456.1 - 0.0011 18.2 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 KFX88456.1 - 0.0027 17.4 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFX88456.1 - 0.0044 16.4 0.1 0.0044 16.4 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX88456.1 - 0.0047 16.0 1.5 0.014 14.5 0.2 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KFX88456.1 - 0.0064 15.4 0.5 0.047 12.5 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 KFX88456.1 - 0.01 16.1 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KFX88456.1 - 0.01 15.4 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KFX88456.1 - 0.015 15.2 0.9 0.027 14.3 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 KFX88458.1 - 0.00097 18.1 0.9 0.0012 17.8 0.9 1.1 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.8 KFX88458.1 - 0.0022 18.0 0.8 0.0031 17.6 0.3 1.3 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DsbD_2 PF13386.6 KFX88458.1 - 0.0087 16.0 0.8 0.015 15.3 0.8 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region NDUF_B12 PF08122.12 KFX88458.1 - 0.055 13.5 1.5 6.6 6.9 0.1 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family adh_short_C2 PF13561.6 KFX88459.1 - 2.4e-57 194.2 1.7 3.7e-57 193.6 1.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX88459.1 - 8e-45 152.7 0.3 1.3e-44 152.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX88459.1 - 1.4e-11 44.6 1.1 2.7e-11 43.7 1.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX88459.1 - 0.015 14.5 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KFX88459.1 - 0.066 13.9 0.1 0.35 11.6 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Fungal_lectin PF07938.12 KFX88464.1 - 3.1e-110 368.3 3.7 3.5e-110 368.1 3.7 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin F-box-like PF12937.7 KFX88465.1 - 0.0004 20.2 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like IMS PF00817.20 KFX88466.1 - 2.8e-40 137.7 0.0 4.6e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KFX88466.1 - 2.3e-13 49.5 3.1 4.6e-13 48.5 3.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KFX88466.1 - 7.2e-13 49.3 0.0 1.9e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFX88466.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.6 KFX88466.1 - 0.15 12.9 1.4 0.52 11.3 1.4 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_M22 PF00814.25 KFX88474.1 - 1.7e-45 155.8 0.0 1e-41 143.4 0.0 2.5 2 1 0 2 2 2 2 Glycoprotease family ANAPC4_WD40 PF12894.7 KFX88474.1 - 0.00092 19.5 0.0 6.4 7.2 0.0 4.4 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX88474.1 - 0.0018 19.1 2.1 1.1 10.2 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Peptidase_M3 PF01432.20 KFX88475.1 - 1.2e-123 413.8 0.0 2.4e-123 412.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 KFX88475.1 - 0.061 13.0 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ArAE_2 PF10334.9 KFX88475.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 ApoO PF09769.9 KFX88476.1 - 1.5e-40 138.1 0.9 3.3e-38 130.6 0.1 2.8 3 0 0 3 3 3 2 Apolipoprotein O IU_nuc_hydro PF01156.19 KFX88477.1 - 6.8e-76 255.7 0.1 1.4e-75 254.8 0.1 1.5 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KFX88477.1 - 5.2e-07 29.5 6.4 1.3e-06 28.2 6.4 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region UCR_UQCRX_QCR9 PF05365.12 KFX88478.1 - 5.1e-24 84.0 1.7 1.2e-23 82.8 1.7 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 KFX88478.1 - 7.6e-19 67.6 14.3 2e-18 66.3 14.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Exo_endo_phos PF03372.23 KFX88478.1 - 9.3e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ClpS PF02617.17 KFX88478.1 - 8.5e-07 28.7 0.1 1.8e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PRIMA1 PF16101.5 KFX88478.1 - 0.086 12.9 3.9 0.19 11.8 3.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KFX88478.1 - 0.13 11.7 4.7 0.25 10.8 4.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mago-bind PF09282.10 KFX88479.1 - 4.2e-14 52.1 3.0 8.9e-14 51.1 3.0 1.6 1 0 0 1 1 1 1 Mago binding T4SS PF07996.11 KFX88479.1 - 0.0037 17.7 1.7 0.0051 17.3 1.7 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins DUF4778 PF16008.5 KFX88479.1 - 0.064 13.3 2.8 0.072 13.1 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Dsh_C PF12316.8 KFX88479.1 - 0.4 11.1 9.0 0.52 10.7 8.7 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 KFX88479.1 - 0.45 9.2 5.5 0.48 9.1 5.5 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KFX88479.1 - 1.7 8.4 10.9 1.9 8.3 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 KFX88479.1 - 9.3 4.2 7.1 11 4.0 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 KFX88479.1 - 9.5 4.8 6.0 9.9 4.7 6.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 KFX88480.1 - 7.3e-53 175.4 21.6 3.5e-10 40.3 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88480.1 - 4.3e-20 71.8 0.1 0.0012 19.1 0.0 6.2 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX88480.1 - 7.7e-09 35.7 0.1 0.098 12.5 0.0 4.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX88480.1 - 7e-07 28.5 0.4 0.059 12.3 0.0 4.7 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KFX88480.1 - 9.8e-07 28.1 1.1 0.33 10.0 0.1 4.2 2 1 2 4 4 4 3 Protein of unknown function (DUF1513) Nup160 PF11715.8 KFX88480.1 - 5.3e-06 25.4 1.5 0.28 9.8 0.0 4.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KFX88480.1 - 4.4e-05 23.0 0.0 0.00016 21.1 0.0 2.0 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFX88480.1 - 0.00095 19.0 1.0 0.64 10.0 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KFX88480.1 - 0.022 13.1 0.0 0.13 10.5 0.0 2.1 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KFX88480.1 - 0.12 11.2 4.6 3.9 6.3 0.3 3.3 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain SLD5_C PF16922.5 KFX88481.1 - 1.4e-13 50.8 0.1 2.8e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KFX88481.1 - 1.1e-06 29.1 0.1 2.1e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Josephin PF02099.17 KFX88481.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Josephin Ppx-GppA PF02541.16 KFX88483.1 - 5e-41 141.0 0.0 6.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KFX88483.1 - 0.18 10.4 0.1 0.29 9.7 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family CwfJ_C_1 PF04677.15 KFX88484.1 - 1.2e-26 93.0 0.0 2.1e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFX88484.1 - 1.2e-16 61.4 0.3 2.7e-16 60.2 0.3 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 KFX88485.1 - 3.8e-196 653.1 13.5 5.3e-196 652.7 9.2 2.8 2 1 0 2 2 2 1 Down-regulated in metastasis Rcd1 PF04078.13 KFX88485.1 - 0.0014 18.0 0.5 0.091 12.0 0.0 3.5 3 0 0 3 3 3 1 Cell differentiation family, Rcd1-like IBN_N PF03810.19 KFX88485.1 - 0.019 14.9 0.6 45 4.1 0.0 4.9 5 0 0 5 5 5 0 Importin-beta N-terminal domain Arm PF00514.23 KFX88485.1 - 0.023 14.8 1.1 18 5.6 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 KFX88485.1 - 0.028 14.2 0.3 2 8.2 0.1 3.4 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal HEAT PF02985.22 KFX88485.1 - 0.65 10.4 2.0 18 5.9 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat zf-DNL PF05180.12 KFX88486.1 - 2.6e-29 100.9 0.7 3.7e-29 100.5 0.7 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 KFX88486.1 - 0.063 13.2 1.6 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cullin PF00888.22 KFX88487.1 - 6.3e-198 659.3 2.4 6.3e-198 659.3 2.4 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFX88487.1 - 3.4e-27 94.3 1.9 8.9e-27 92.9 1.9 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain YpjP PF14005.6 KFX88487.1 - 0.024 14.7 1.5 0.62 10.1 0.0 3.1 4 0 0 4 4 4 0 YpjP-like protein adh_short PF00106.25 KFX88488.1 - 2.5e-34 118.4 2.2 3.8e-34 117.9 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 KFX88488.1 - 1e-29 103.6 28.5 1e-29 103.6 28.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KFX88488.1 - 4e-24 85.5 0.9 6.4e-24 84.8 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX88488.1 - 7.2e-10 39.1 5.0 1.1e-08 35.3 4.9 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX88488.1 - 3.9e-06 26.5 0.1 7.8e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX88488.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX88488.1 - 0.0029 16.7 0.1 0.0048 15.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX88488.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KFX88488.1 - 0.045 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEDD_Tnp_IS110 PF01548.17 KFX88488.1 - 0.045 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Transposase NmrA PF05368.13 KFX88488.1 - 0.054 13.1 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 KFX88488.1 - 0.078 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 KFX88488.1 - 0.1 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DUF2530 PF10745.9 KFX88488.1 - 1.6 9.0 8.3 0.27 11.5 0.4 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF2530) Aa_trans PF01490.18 KFX88492.1 - 7.8e-72 242.2 25.9 1e-71 241.8 25.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tcp11 PF05794.13 KFX88493.1 - 2.5e-67 227.9 0.0 3.6e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 zf-RING_2 PF13639.6 KFX88494.1 - 2.4e-06 27.8 4.9 2.4e-06 27.8 4.9 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 KFX88494.1 - 0.00012 21.9 5.2 0.00016 21.5 2.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.17 KFX88494.1 - 0.0039 16.8 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_UBOX PF13445.6 KFX88494.1 - 0.078 13.0 2.9 0.17 11.9 2.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 KFX88494.1 - 0.22 11.5 6.4 0.46 10.4 6.4 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KFX88494.1 - 1.2 9.1 7.1 0.66 9.9 2.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHF5 PF03660.14 KFX88494.1 - 2.3 8.4 7.8 0.17 12.1 2.7 1.7 2 0 0 2 2 1 0 PHF5-like protein zf-C3HC4_2 PF13923.6 KFX88494.1 - 3.6 7.5 7.1 0.21 11.4 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX88494.1 - 7.6 6.9 8.6 0.55 10.6 3.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain SCRL PF06876.12 KFX88494.1 - 9.4 6.5 10.3 1.3 9.3 3.1 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-C3HC4 PF00097.25 KFX88494.1 - 9.8 6.2 8.8 0.37 10.7 2.2 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S10 PF00450.22 KFX88495.1 - 2.6e-76 257.7 0.2 8.7e-76 256.0 0.2 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase RRN3 PF05327.11 KFX88496.1 - 1.5 7.3 9.1 3.2 6.2 9.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1192 PF06698.11 KFX88498.1 - 0.77 9.9 3.7 0.51 10.4 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SNF2_N PF00176.23 KFX88499.1 - 4.7e-27 94.6 0.0 1.1e-26 93.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX88499.1 - 3e-09 37.2 0.0 7.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX88499.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KFX88499.1 - 0.098 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Rnk_N PF14760.6 KFX88500.1 - 0.088 13.3 0.3 1.3 9.6 0.1 2.6 2 0 0 2 2 2 0 Rnk N-terminus Filament PF00038.21 KFX88501.1 - 0.0007 19.3 119.3 0.0048 16.5 17.4 6.5 2 2 3 5 5 5 4 Intermediate filament protein APG6_N PF17675.1 KFX88501.1 - 0.004 17.7 21.0 0.004 17.7 21.0 10.4 1 1 6 8 8 8 2 Apg6 coiled-coil region EFG_II PF14492.6 KFX88501.1 - 0.097 12.8 0.9 0.41 10.8 0.9 2.1 1 0 0 1 1 1 0 Elongation Factor G, domain II Glyco_hydro_2_C PF02836.17 KFX88503.1 - 1.4e-85 287.1 0.0 2.2e-85 286.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFX88503.1 - 1.2e-26 93.6 0.5 2.5e-26 92.6 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFX88503.1 - 6.1e-11 43.0 0.3 1.3e-10 41.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Acyl_transf_3 PF01757.22 KFX88505.1 - 5e-28 98.1 25.6 5e-28 98.1 25.6 2.1 2 0 0 2 2 2 2 Acyltransferase family S36_mt PF10937.8 KFX88516.1 - 2e-40 138.9 0.8 2.4e-40 138.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 KFX88517.1 - 9.3e-26 91.2 0.0 1.1e-25 91.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein ING PF12998.7 KFX88519.1 - 0.0005 20.6 0.6 0.0025 18.4 0.6 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Lge1 PF11488.8 KFX88521.1 - 0.086 13.0 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HflK_N PF12221.8 KFX88521.1 - 0.1 12.6 0.2 0.57 10.2 0.1 2.3 3 0 0 3 3 3 0 Bacterial membrane protein N terminal Acyl-CoA_dh_2 PF08028.11 KFX88521.1 - 0.15 12.3 3.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.21 KFX88522.1 - 1.1e-30 106.8 0.0 1.5e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2431 PF10354.9 KFX88523.1 - 4e-66 222.4 0.0 5.1e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Ank_2 PF12796.7 KFX88524.1 - 4e-26 91.4 0.0 9.6e-10 38.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Myb_DNA-bind_7 PF15963.5 KFX88524.1 - 8.7e-24 83.2 1.0 8.7e-24 83.2 1.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like Ank_3 PF13606.6 KFX88524.1 - 2.4e-21 73.5 0.1 0.0012 19.1 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KFX88524.1 - 4.6e-20 71.7 0.0 1.4e-06 28.7 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX88524.1 - 1.7e-18 66.4 0.1 2.9e-06 27.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX88524.1 - 6e-18 64.4 1.5 0.0024 18.2 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.12 KFX88524.1 - 2.4e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KFX88524.1 - 7.8e-06 26.1 0.3 0.00053 20.2 0.0 2.7 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KFX88524.1 - 9.4e-05 22.7 0.0 0.00032 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX88524.1 - 0.00019 21.9 0.1 0.0033 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Myb_DNA-binding PF00249.31 KFX88524.1 - 0.00064 19.9 0.0 0.002 18.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain NB-ARC PF00931.22 KFX88524.1 - 0.075 12.2 0.0 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain BRE1 PF08647.11 KFX88525.1 - 2.2e-27 95.0 5.0 2.2e-27 95.0 5.0 6.7 4 1 2 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KFX88525.1 - 2.5e-08 33.7 8.5 4e-08 33.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX88525.1 - 2.5e-07 30.4 11.7 4.4e-07 29.7 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX88525.1 - 8.9e-07 28.7 7.6 1.5e-06 27.9 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFX88525.1 - 1.6e-06 27.9 10.0 2.7e-06 27.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX88525.1 - 1.7e-06 27.9 6.2 3.1e-06 27.1 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFX88525.1 - 2.3e-06 27.8 9.1 3.8e-06 27.1 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX88525.1 - 6.3e-06 26.1 11.3 1e-05 25.4 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ATG16 PF08614.11 KFX88525.1 - 0.002 18.4 21.1 0.002 18.4 21.1 6.0 3 2 3 6 6 6 2 Autophagy protein 16 (ATG16) DUF1272 PF06906.11 KFX88525.1 - 0.012 15.7 7.3 0.023 14.8 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KFX88525.1 - 0.076 12.8 7.4 0.24 11.2 7.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFX88525.1 - 0.097 12.8 6.5 0.18 12.0 6.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFX88525.1 - 0.21 11.9 9.3 1.1 9.6 9.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 KFX88525.1 - 0.25 11.5 3.9 0.73 10.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc-ribbons_6 PF07191.12 KFX88525.1 - 1.6 8.8 7.7 0.77 9.8 2.9 2.3 1 1 1 2 2 2 0 zinc-ribbons FYVE PF01363.21 KFX88525.1 - 1.7 8.8 11.3 19 5.5 11.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 KFX88525.1 - 1.8 8.9 7.2 47 4.4 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-ANAPC11 PF12861.7 KFX88525.1 - 2 8.5 4.8 7.6 6.7 4.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 KFX88525.1 - 3.5 8.7 6.5 17 6.6 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger DinB_2 PF12867.7 KFX88525.1 - 3.5 8.1 8.6 0.57 10.7 2.3 3.0 3 1 0 3 3 2 0 DinB superfamily Baculo_PEP_C PF04513.12 KFX88525.1 - 3.8 7.6 31.9 3.1 7.8 0.2 5.6 3 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus HLH PF00010.26 KFX88527.1 - 1.3e-11 44.3 1.8 3.7e-11 42.8 1.8 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 KFX88527.1 - 0.056 12.4 2.3 0.086 11.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Ly49 PF08391.10 KFX88527.1 - 0.077 13.4 0.8 0.15 12.4 0.8 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DivIC PF04977.15 KFX88527.1 - 0.22 11.3 1.2 0.72 9.7 1.2 1.8 1 0 0 1 1 1 0 Septum formation initiator Mod_r PF07200.13 KFX88527.1 - 0.26 11.4 6.6 0.36 10.9 5.1 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CBP4 PF07960.11 KFX88527.1 - 1.1 9.1 11.0 1.5 8.7 9.4 2.0 2 0 0 2 2 2 0 CBP4 APG6_N PF17675.1 KFX88527.1 - 2.5 8.7 10.9 5.3 7.6 10.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region RNA_pol_Rbc25 PF08292.12 KFX88529.1 - 2.5e-28 98.9 0.0 3.8e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFX88529.1 - 1.3e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Trypan_PARP PF05887.11 KFX88539.1 - 9.9e-06 25.6 0.5 1.2e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KFX88539.1 - 0.096 11.9 3.1 0.17 11.1 3.1 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Adeno_E1A PF02703.14 KFX88539.1 - 0.12 11.9 2.9 0.15 11.7 2.9 1.1 1 0 0 1 1 1 0 Early E1A protein Ferric_reduct PF01794.19 KFX88540.1 - 1.5e-13 50.9 2.9 1.5e-13 50.9 2.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX88540.1 - 4.7e-08 33.1 0.0 1.6e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX88540.1 - 2.1e-05 24.7 0.0 8.5e-05 22.7 0.0 2.0 3 0 0 3 3 3 1 Ferric reductase NAD binding domain YdfZ PF14001.6 KFX88540.1 - 0.064 13.7 0.1 4.4 7.8 0.0 2.5 2 0 0 2 2 2 0 YdfZ protein Ank_2 PF12796.7 KFX88543.1 - 3.3e-49 165.4 1.2 2.2e-13 50.6 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX88543.1 - 2.3e-44 149.2 11.5 1.9e-10 41.0 0.3 6.9 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX88543.1 - 2.6e-41 134.9 10.2 2.7e-05 24.2 0.0 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 KFX88543.1 - 2.2e-36 122.7 14.1 1.3e-05 25.4 0.3 9.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KFX88543.1 - 7.2e-30 102.7 14.5 5.3e-06 26.6 0.3 7.6 1 1 8 9 9 9 8 Ankyrin repeats (many copies) DUF1843 PF08898.10 KFX88543.1 - 0.033 14.7 0.5 32 5.1 0.1 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) DUF3447 PF11929.8 KFX88543.1 - 0.13 12.2 0.0 15 5.6 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) DUF4305 PF14146.6 KFX88544.1 - 0.07 13.3 0.2 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) DUF3767 PF12597.8 KFX88544.1 - 0.13 12.1 0.9 0.21 11.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) HTH_38 PF13936.6 KFX88546.1 - 1.4e-05 24.8 0.6 0.00024 20.8 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain CENP-B_N PF04218.13 KFX88546.1 - 0.0045 16.6 2.6 0.0081 15.8 0.8 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DUF2197 PF09963.9 KFX88546.1 - 0.035 14.4 0.1 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Cro PF09048.10 KFX88546.1 - 0.038 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Cro Glyco_hydro_26 PF02156.15 KFX88551.1 - 0.15 11.5 0.2 0.5 9.8 0.0 1.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 26 Cu_bind_like PF02298.17 KFX88551.1 - 0.17 11.9 0.1 0.38 10.8 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Alpha_GJ PF03229.13 KFX88551.1 - 3.6 8.2 14.6 0.52 10.9 8.8 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Ferritin_2 PF13668.6 KFX88552.1 - 3.3e-20 72.7 0.5 4.9e-20 72.1 0.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain Transketolase_N PF00456.21 KFX88552.1 - 0.055 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain VirK PF06903.12 KFX88553.1 - 0.00056 19.9 0.2 0.0013 18.7 0.1 1.6 2 0 0 2 2 2 1 VirK protein CCDC73 PF15818.5 KFX88553.1 - 0.0043 15.0 1.6 0.0049 14.8 1.6 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 73 family SE PF08491.10 KFX88554.1 - 0.0031 16.6 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Phytochelatin_C PF09328.10 KFX88555.1 - 0.12 11.7 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) 4HB_MCP_1 PF12729.7 KFX88555.1 - 0.19 11.3 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DDE_3 PF13358.6 KFX88556.1 - 1.6e-12 47.4 0.5 4.4e-12 46.0 0.5 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFX88556.1 - 2.6e-08 34.0 0.1 1.4e-07 31.7 0.0 2.3 1 1 1 2 2 2 1 Transposase HTH_40 PF14493.6 KFX88556.1 - 0.0012 19.3 0.2 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFX88556.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 KFX88556.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFX88556.1 - 0.0086 15.8 0.7 0.05 13.4 0.1 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_24 PF13412.6 KFX88556.1 - 0.014 15.0 0.0 0.047 13.3 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding UPF0122 PF04297.14 KFX88556.1 - 0.022 15.0 0.1 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.16 KFX88556.1 - 0.023 14.2 0.0 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_7 PF02796.15 KFX88556.1 - 0.1 12.7 0.2 0.71 10.0 0.1 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain of resolvase TetR_N PF00440.23 KFX88556.1 - 0.14 12.0 0.1 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Zn_Tnp_IS1595 PF12760.7 KFX88556.1 - 0.88 9.6 5.7 0.8 9.7 0.4 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain MerR PF00376.23 KFX88556.1 - 1.7 8.4 5.0 1.9 8.3 0.1 2.9 3 0 0 3 3 3 0 MerR family regulatory protein Fungal_trans PF04082.18 KFX88568.1 - 1.6e-12 47.0 0.5 2.7e-12 46.3 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88568.1 - 2e-07 31.0 13.9 3.4e-07 30.3 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RBR PF17208.3 KFX88568.1 - 0.01 16.5 0.5 0.028 15.1 0.5 1.8 1 0 0 1 1 1 0 RNA binding Region AAA PF00004.29 KFX88570.1 - 5.2e-38 130.5 0.0 7.1e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX88570.1 - 1.6e-12 47.0 0.9 7.8e-12 44.8 0.1 2.5 2 1 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KFX88570.1 - 0.013 15.2 0.0 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFX88570.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 KFX88570.1 - 0.044 13.8 0.1 0.33 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX88570.1 - 0.074 13.2 0.2 0.17 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KFX88570.1 - 0.081 12.3 0.2 0.18 11.2 0.2 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFX88570.1 - 0.086 13.2 0.1 0.43 11.0 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 KFX88570.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Profilin PF00235.19 KFX88571.1 - 1.5e-47 161.0 0.7 1.6e-47 160.9 0.7 1.0 1 0 0 1 1 1 1 Profilin Pterin_4a PF01329.19 KFX88572.1 - 9.5e-14 51.3 0.1 1.1e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Mito_carr PF00153.27 KFX88575.1 - 4.8e-56 186.7 3.9 3.7e-23 81.3 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Pyr_redox_2 PF07992.14 KFX88585.1 - 1.4e-38 132.8 0.0 4.9e-35 121.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX88585.1 - 1.2e-07 32.2 0.0 1.2e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF3446 PF11928.8 KFX88585.1 - 0.43 10.9 10.9 5.1 7.5 2.8 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain NAPRTase PF04095.16 KFX88586.1 - 6.9e-51 173.2 0.0 9.1e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KFX88586.1 - 3.1e-34 118.0 0.1 5.6e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3464 PF11947.8 KFX88586.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 KFX88587.1 - 6.9e-20 71.3 83.8 1.9e-14 53.3 47.1 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 KFX88588.1 - 5.5e-24 85.4 11.9 1.8e-16 60.6 1.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 bZIP_1 PF00170.21 KFX88589.1 - 4.3e-07 29.9 6.3 4.3e-07 29.9 6.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX88589.1 - 0.015 15.4 6.8 0.024 14.7 6.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KFX88589.1 - 1.8 9.1 8.2 0.13 12.8 3.6 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor GAS2 PF02187.17 KFX88593.1 - 7.5e-07 29.2 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Nucleoporin_C PF03177.14 KFX88593.1 - 0.2 10.4 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Glyco_hydro_61 PF03443.14 KFX88595.1 - 2e-61 207.5 0.0 3.1e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFX88595.1 - 1.2e-11 44.3 10.2 1.2e-11 44.3 10.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain HTH_Tnp_ISL3 PF13542.6 KFX88595.1 - 0.083 12.3 0.2 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Amino_oxidase PF01593.24 KFX88596.1 - 6.7e-43 147.6 0.0 1.8e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX88596.1 - 9.2e-12 45.0 0.0 3e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX88596.1 - 4.1e-06 26.3 0.0 8.4e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX88596.1 - 0.00027 19.8 0.1 0.00044 19.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KFX88596.1 - 0.0013 18.0 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX88596.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX88596.1 - 0.032 14.8 0.1 0.077 13.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX88596.1 - 0.052 12.6 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFX88596.1 - 0.11 12.5 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KFX88596.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.13 KFX88597.1 - 5e-31 108.2 0.0 9.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFX88597.1 - 1.6e-30 106.5 0.0 4.5e-25 88.6 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KFX88597.1 - 0.00012 22.3 1.7 0.00031 20.9 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX88597.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX88597.1 - 0.0065 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX88597.1 - 0.039 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KFX88597.1 - 0.073 12.7 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFX88597.1 - 0.086 11.5 0.3 0.12 11.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFX88597.1 - 0.16 11.2 0.1 14 4.8 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX88597.1 - 0.48 9.9 3.3 2.6 7.6 2.2 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Inv-AAD PF18785.1 KFX88603.1 - 3.6e-65 217.7 0.3 4.2e-65 217.4 0.3 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KFX88603.1 - 4.3e-15 55.4 0.1 7.2e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KFX88603.1 - 3.9e-05 23.6 0.2 0.0001 22.2 0.2 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 KFX88603.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.5 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KFX88603.1 - 0.037 14.1 0.1 0.056 13.5 0.1 1.3 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 MafB19-deam PF14437.6 KFX88603.1 - 0.049 13.4 0.2 0.099 12.4 0.1 1.5 1 1 0 1 1 1 0 MafB19-like deaminase Mit_ribos_Mrp51 PF11709.8 KFX88604.1 - 7.3e-128 427.2 0.1 9.4e-128 426.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KFX88605.1 - 2e-60 202.0 0.6 2.4e-60 201.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 KFX88606.1 - 1.7e-19 69.9 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.6 KFX88607.1 - 1.9e-10 40.4 0.3 5.9e-10 38.8 0.4 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFX88607.1 - 1.1e-09 37.8 0.2 2.7e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX88607.1 - 3e-09 36.4 0.1 6.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_phi PF04931.13 KFX88607.1 - 9.2 4.2 6.2 17 3.3 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pectate_lyase_3 PF12708.7 KFX88609.1 - 9.6e-103 342.6 17.1 3.9e-87 291.6 3.2 2.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein WSC PF01822.19 KFX88609.1 - 1.8e-17 63.3 6.8 5.2e-17 61.8 6.8 1.8 1 0 0 1 1 1 1 WSC domain End_N_terminal PF12218.8 KFX88609.1 - 6.6e-08 32.1 3.6 0.0056 16.3 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_cc PF11790.8 KFX88610.1 - 3.2e-54 184.0 6.5 4e-54 183.7 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WSC PF01822.19 KFX88610.1 - 1e-18 67.3 16.2 3.1e-18 65.8 10.3 2.6 2 0 0 2 2 2 2 WSC domain DUF1996 PF09362.10 KFX88611.1 - 5.7e-10 39.6 0.4 6.8e-10 39.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Collagen_mid PF15984.5 KFX88612.1 - 0.085 12.6 2.7 0.099 12.4 2.7 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region EOS1 PF12326.8 KFX88612.1 - 0.094 12.6 0.9 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein Vma12 PF11712.8 KFX88612.1 - 0.2 11.7 6.2 0.92 9.6 6.2 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.16 KFX88613.1 - 3e-25 88.9 46.1 1.5e-19 70.1 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX88613.1 - 3e-12 46.2 0.2 3e-12 46.2 0.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFX88613.1 - 0.0034 16.3 4.9 0.0034 16.3 4.9 2.5 2 2 0 2 2 2 1 MFS_1 like family Img2 PF05046.14 KFX88615.1 - 6.1e-25 87.3 0.2 1.1e-24 86.6 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 KFX88616.1 - 2.1e-48 164.1 3.5 2.1e-48 164.1 3.5 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFX88616.1 - 5.5e-14 52.6 0.2 1.6e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 PCI domain VPR PF00522.18 KFX88616.1 - 0.077 13.0 0.2 0.74 9.9 0.0 2.7 3 0 0 3 3 3 0 VPR/VPX protein DUF4267 PF14087.6 KFX88617.1 - 1.3e-17 63.8 0.6 1.7e-17 63.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Glyco_hydro_106 PF17132.4 KFX88619.1 - 7.5e-21 74.1 0.5 4.1e-20 71.7 0.4 2.0 3 0 0 3 3 3 1 alpha-L-rhamnosidase PGAP1 PF07819.13 KFX88622.1 - 0.00016 21.4 0.1 0.00097 18.9 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX88622.1 - 0.031 14.9 0.2 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA PF00004.29 KFX88623.1 - 1.7e-16 60.9 0.0 6.9e-16 58.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX88623.1 - 0.00066 20.0 2.6 0.014 15.7 0.1 3.1 3 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KFX88623.1 - 0.0012 19.2 0.0 0.0078 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFX88623.1 - 0.0057 16.7 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.12 KFX88623.1 - 0.013 15.3 0.0 0.15 11.9 0.0 2.4 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 KFX88623.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX88623.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KFX88623.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Kelch_6 PF13964.6 KFX88629.1 - 0.0015 18.7 3.1 0.086 13.2 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Mid2 PF04478.12 KFX88629.1 - 0.0053 16.6 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 KFX88629.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 KFX88629.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family UL45 PF05473.12 KFX88629.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Adeno_E3_CR2 PF02439.15 KFX88629.1 - 0.37 10.6 1.1 0.75 9.6 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KFX88629.1 - 0.41 10.6 1.3 0.78 9.7 1.3 1.4 1 0 0 1 1 1 0 Syndecan domain Cellulase PF00150.18 KFX88630.1 - 2.5e-31 109.1 0.0 3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 KFX88634.1 - 1.3e-50 172.5 0.0 1.8e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 KFX88635.1 - 3.4e-10 40.3 0.0 1e-09 38.8 0.0 1.8 1 1 0 1 1 1 1 Putative cyclase HD PF01966.22 KFX88636.1 - 6.4e-07 29.6 0.8 2.1e-06 27.9 0.3 1.9 2 0 0 2 2 2 1 HD domain Carboxyl_trans PF01039.22 KFX88637.1 - 1.1e-75 255.2 0.0 1.4e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFX88638.1 - 1.7e-55 187.8 0.0 2.4e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFX88638.1 - 2.6e-30 104.7 0.0 4.4e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFX88638.1 - 5e-27 94.6 0.0 8.9e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFX88638.1 - 1.2e-10 41.0 1.0 6.8e-10 38.6 1.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX88638.1 - 9.5e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX88638.1 - 0.00036 20.1 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFX88638.1 - 0.0009 19.3 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KFX88638.1 - 0.0019 17.5 0.0 0.0051 16.1 0.0 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Biotin_lipoyl_2 PF13533.6 KFX88638.1 - 0.0024 17.6 0.1 0.0051 16.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-lipoyl like DUF2118 PF09891.9 KFX88638.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_Ter PF15632.6 KFX88638.1 - 0.035 13.8 0.1 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 KFX88638.1 - 0.036 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ProQ_C PF17516.2 KFX88638.1 - 0.11 11.9 0.5 14 5.2 0.0 2.4 2 0 0 2 2 2 0 ProQ C-terminal domain SNF2_N PF00176.23 KFX88640.1 - 2.8e-49 167.7 0.0 4.6e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KFX88640.1 - 1.7e-23 82.5 0.4 1.7e-23 82.5 0.4 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KFX88640.1 - 1.2e-20 73.9 0.0 8.6e-20 71.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX88640.1 - 3.3e-09 37.0 0.0 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFX88640.1 - 6.9e-07 28.7 0.7 1.4e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KFX88640.1 - 0.00017 21.4 0.0 0.00086 19.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KFX88640.1 - 0.085 11.7 4.0 0.22 10.4 1.9 2.4 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 But2 PF09792.9 KFX88641.1 - 1.6e-33 116.1 0.8 3.3e-33 115.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.16 KFX88642.1 - 1.6e-36 125.9 53.9 2.8e-36 125.2 53.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily NmrA PF05368.13 KFX88642.1 - 6.4e-33 114.2 0.0 1.2e-32 113.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX88642.1 - 4e-12 46.4 0.0 6.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sugar_tr PF00083.24 KFX88642.1 - 8.8e-09 34.7 15.4 8.8e-09 34.7 15.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Dpy19 PF10034.9 KFX88642.1 - 0.1 10.8 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation 3Beta_HSD PF01073.19 KFX88642.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydr_30_2 PF14587.6 KFX88643.1 - 4.4e-17 62.7 6.4 8.4e-17 61.8 6.4 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.12 KFX88644.1 - 3.1e-24 86.0 0.1 4.8e-24 85.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Oxidored_molyb PF00174.19 KFX88645.1 - 6e-57 192.0 0.0 9.8e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFX88645.1 - 5.9e-36 123.5 0.3 1.2e-35 122.5 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KFX88645.1 - 1.3e-26 93.3 0.0 7.2e-26 91.0 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFX88645.1 - 4.4e-23 81.5 0.0 9e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KFX88645.1 - 1.9e-14 53.5 0.1 4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFX88645.1 - 0.027 14.6 0.0 1.8 8.7 0.0 2.8 1 1 0 2 2 2 0 Ferric reductase NAD binding domain p450 PF00067.22 KFX88646.1 - 1.3e-56 192.4 0.0 1.5e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 KFX88648.1 - 7.1e-23 81.5 0.4 1.3e-22 80.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_2 PF00891.18 KFX88648.1 - 1.5e-21 76.6 0.0 5.5e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Acyl-CoA_dh_N PF02771.16 KFX88648.1 - 1.9e-11 44.6 0.0 1.1e-10 42.1 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX88648.1 - 1.2e-06 28.6 0.0 3.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX88648.1 - 5.1e-06 26.8 1.9 1.1e-05 25.7 1.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Dimerisation2 PF16864.5 KFX88648.1 - 0.00045 20.1 0.1 0.0014 18.6 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain Ad_Cy_reg PF16701.5 KFX88648.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain Sugar_tr PF00083.24 KFX88649.1 - 8e-110 367.8 24.8 9.9e-110 367.5 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88649.1 - 1.6e-19 70.0 41.8 4.7e-13 48.8 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 KFX88651.1 - 2.7e-72 238.8 108.0 4.3e-11 42.7 8.5 7.5 7 0 0 7 7 7 7 CFEM domain Esterase_phd PF10503.9 KFX88652.1 - 1.5e-26 93.3 0.2 2e-26 92.9 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX88652.1 - 1.7e-07 30.9 0.5 3.1e-07 30.1 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX88652.1 - 0.064 12.1 0.3 0.12 11.3 0.3 1.4 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.16 KFX88654.1 - 6e-35 120.8 25.9 8.8e-35 120.3 25.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KFX88654.1 - 0.12 12.2 2.3 0.44 10.3 2.0 2.2 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Carb_anhydrase PF00194.21 KFX88655.1 - 0.00086 18.9 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase zf-CCHC PF00098.23 KFX88656.1 - 4.9e-53 175.0 65.5 1.6e-09 37.4 2.3 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KFX88656.1 - 6.5e-11 41.8 38.0 0.13 12.1 0.6 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KFX88656.1 - 1.9e-07 31.0 50.9 0.02 14.8 0.4 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 KFX88656.1 - 0.016 15.0 1.3 0.016 15.0 1.3 7.2 8 0 0 8 8 8 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFX88656.1 - 0.03 14.1 8.7 0.057 13.3 2.0 7.1 5 2 2 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.6 KFX88656.1 - 0.034 13.9 45.8 0.79 9.5 0.4 7.1 4 2 3 7 7 7 0 GAG-polyprotein viral zinc-finger CFEM PF05730.11 KFX88659.1 - 3.2e-10 40.0 13.5 5.5e-10 39.2 13.5 1.4 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.9 KFX88659.1 - 0.68 9.1 5.5 0.77 8.9 5.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 KFX88663.1 - 0.42 10.6 3.8 0.44 10.5 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KFX88663.1 - 0.69 8.5 3.9 0.73 8.5 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short PF00106.25 KFX88665.1 - 5.9e-23 81.3 0.2 6.6e-17 61.6 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX88665.1 - 2.7e-10 40.2 0.0 7.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX88665.1 - 7.1e-08 32.6 0.7 1.1e-07 31.9 0.7 1.3 1 0 0 1 1 1 1 KR domain RabGAP-TBC PF00566.18 KFX88668.1 - 5.7e-48 163.4 0.0 1e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PRP1_N PF06424.12 KFX88668.1 - 7.7 6.9 15.6 0.066 13.6 4.8 2.9 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Glyco_hydro_61 PF03443.14 KFX88680.1 - 2.9e-48 164.5 0.0 3.3e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.28 KFX88683.1 - 1.1e-72 245.6 0.0 2.2e-72 244.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX88683.1 - 5.1e-12 46.1 0.1 1.8e-11 44.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 KFX88685.1 - 3.5e-14 53.2 0.4 3.1e-09 37.0 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFX88685.1 - 0.0021 17.3 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 CsiD Fungal_trans PF04082.18 KFX88686.1 - 7e-06 25.3 0.0 0.0025 16.9 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88686.1 - 2.7e-05 24.2 10.3 5.8e-05 23.1 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.26 KFX88687.1 - 7.3e-113 378.0 2.4 1.2e-112 377.4 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFX88687.1 - 1.7e-06 28.3 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KFX88687.1 - 0.00073 19.8 3.1 0.0016 18.7 0.2 2.9 2 1 0 2 2 2 1 Galactose mutarotase-like Sugar_tr PF00083.24 KFX88688.1 - 1.1e-88 298.2 22.8 1.3e-88 297.9 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88688.1 - 1.3e-19 70.4 26.2 1.3e-19 70.4 26.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.6 KFX88688.1 - 4.1 6.9 7.0 0.14 11.6 0.5 1.9 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Glyco_hydro_39 PF01229.17 KFX88689.1 - 0.0047 15.6 0.2 0.0066 15.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_43 PF04616.14 KFX88690.1 - 1.3e-40 139.6 3.1 1.8e-40 139.1 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX88690.1 - 4.2e-28 98.5 0.0 5.7e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain FAD_binding_3 PF01494.19 KFX88691.1 - 7.1e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain APG6_N PF17675.1 KFX88692.1 - 0.0049 17.4 4.4 0.012 16.1 4.4 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region SPATA3 PF15662.5 KFX88696.1 - 0.77 10.4 6.6 0.048 14.3 1.6 1.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family DUF4106 PF13388.6 KFX88696.1 - 5 6.2 7.7 7.1 5.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peptidase_C48 PF02902.19 KFX88697.1 - 0.0004 20.3 0.1 0.00079 19.3 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.29 KFX88697.1 - 0.0031 17.4 10.3 0.0066 16.3 10.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 KFX88697.1 - 0.046 13.8 9.2 0.13 12.4 9.2 1.8 1 0 0 1 1 1 0 PHD-finger DUF3295 PF11702.8 KFX88699.1 - 2.5e-130 436.2 29.6 9.2e-118 394.7 25.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) zf-U1 PF06220.12 KFX88699.1 - 0.12 12.2 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 U1 zinc finger Methyltransf_23 PF13489.6 KFX88700.1 - 1.4e-16 60.7 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX88700.1 - 2.1e-07 31.6 0.0 9.8e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX88700.1 - 1.8e-06 28.5 0.0 4.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX88700.1 - 5.9e-06 26.9 0.0 0.00017 22.2 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX88700.1 - 7.1e-05 22.6 0.0 0.0011 18.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFX88700.1 - 0.0016 18.6 0.0 0.005 17.0 0.0 1.6 1 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KFX88700.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KFX88700.1 - 0.048 13.1 0.0 0.18 11.2 0.0 1.9 3 0 0 3 3 3 0 Putative methyltransferase RRM_1 PF00076.22 KFX88701.1 - 3.4e-21 74.8 0.1 4.1e-09 36.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HD_3 PF13023.6 KFX88701.1 - 1.2e-19 70.8 0.1 2.6e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 HD domain Abhydrolase_3 PF07859.13 KFX88701.1 - 1.3e-17 64.3 0.0 2.7e-16 60.1 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold ADK PF00406.22 KFX88701.1 - 3.2e-08 33.8 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase Peptidase_S9 PF00326.21 KFX88701.1 - 2.1e-07 30.7 0.0 2.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX88701.1 - 9.8e-05 21.4 0.0 0.00023 20.2 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family HD_2 PF12917.7 KFX88701.1 - 0.00018 21.3 0.1 0.00038 20.3 0.1 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme DLH PF01738.18 KFX88701.1 - 0.0026 17.3 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFX88701.1 - 0.0032 18.1 0.3 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KFX88701.1 - 0.0038 16.2 0.0 0.0088 15.0 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF4807 PF16065.5 KFX88701.1 - 0.018 14.7 0.2 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4807) Chlorophyllase PF07224.11 KFX88701.1 - 0.066 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase HD PF01966.22 KFX88701.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 HD domain Zn_clus PF00172.18 KFX88701.1 - 0.88 9.7 9.0 2.2 8.5 9.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DENN PF02141.21 KFX88704.1 - 7.1e-40 136.9 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFX88704.1 - 3.5e-06 27.7 0.0 1.2e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 uDENN domain MCC-bdg_PDZ PF10506.9 KFX88704.1 - 0.0092 16.0 2.3 0.18 11.9 2.0 2.9 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Queuosine_synth PF02547.15 KFX88704.1 - 0.024 13.8 0.6 0.042 13.0 0.6 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein Glyco_hydro_108 PF05838.12 KFX88704.1 - 0.1 13.1 0.0 0.72 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Elongin_A PF06881.11 KFX88704.1 - 0.91 10.1 10.3 0.03 14.8 3.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cnn_1N PF07989.11 KFX88704.1 - 2.6 8.3 13.7 0.59 10.3 2.2 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BRE1 PF08647.11 KFX88704.1 - 7.1 6.8 17.8 0.23 11.5 6.8 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Melibiase_2 PF16499.5 KFX88709.1 - 1.4e-56 191.7 6.9 5e-38 130.9 0.4 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KFX88709.1 - 1.4e-09 37.9 1.7 6.2e-09 35.8 0.1 2.6 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX88709.1 - 1.4e-06 27.6 0.1 3.6e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Melibiase Alpha-amylase PF00128.24 KFX88710.1 - 3.5e-23 82.7 1.0 7.2e-23 81.7 1.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KFX88710.1 - 0.00032 20.8 0.5 0.0009 19.4 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KFX88710.1 - 0.00047 18.5 0.3 1.6 6.8 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Fungal_trans PF04082.18 KFX88713.1 - 1.7e-16 60.1 3.0 2.8e-16 59.4 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KFX88715.1 - 1.8e-34 119.1 0.0 2.3e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Bestrophin PF01062.21 KFX88717.1 - 3.7e-39 134.9 0.0 5.9e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.7 KFX88718.1 - 1.7e-105 345.8 30.7 8.3e-15 55.1 0.1 11.1 4 2 9 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX88718.1 - 1.8e-72 238.8 11.3 3.4e-07 30.7 0.0 17.6 7 5 11 18 18 18 16 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX88718.1 - 7.7e-68 216.4 25.5 0.0019 18.5 0.0 23.3 24 0 0 24 24 24 16 Ankyrin repeat Ank PF00023.30 KFX88718.1 - 1.2e-52 174.2 44.2 0.00012 22.3 0.1 21.1 22 0 0 22 22 22 14 Ankyrin repeat Ank_5 PF13857.6 KFX88718.1 - 1.2e-39 133.8 26.9 0.00039 20.7 0.2 16.8 9 4 10 19 19 19 12 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 KFX88718.1 - 9.9 6.5 6.3 23 5.4 0.1 4.2 5 1 1 6 6 6 0 Phage T7 capsid assembly protein COesterase PF00135.28 KFX88720.1 - 5.4e-65 220.2 0.0 6.9e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX88720.1 - 0.0068 16.3 0.1 0.059 13.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX88720.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SelK_SelG PF10961.8 KFX88723.1 - 0.046 14.3 0.3 0.046 14.3 0.3 2.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF4293 PF14126.6 KFX88723.1 - 0.23 11.7 5.1 0.068 13.4 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF5337 PF17272.2 KFX88723.1 - 4.9 7.1 10.7 2.9 7.8 4.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5337) DUF2157 PF09925.9 KFX88723.1 - 6.3 6.6 11.5 9.2 6.0 5.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) APH PF01636.23 KFX88725.1 - 1.7e-21 77.3 0.0 3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX88725.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_hydro_25 PF01183.20 KFX88726.1 - 3.6e-39 134.8 0.3 4.2e-39 134.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 NAD_binding_10 PF13460.6 KFX88727.1 - 4.5e-05 23.4 0.0 5.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX88727.1 - 0.0016 17.9 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX88727.1 - 0.011 15.0 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 KFX88727.1 - 0.083 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KFX88728.1 - 1.6e-45 155.7 0.0 1.4e-42 146.0 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 PUD1_2 PF18457.1 KFX88728.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 DUF5035 PF16438.5 KFX88730.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5035) Amidohydro_1 PF01979.20 KFX88732.1 - 3e-06 26.8 1.3 5.9e-06 25.8 1.3 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KFX88732.1 - 0.00022 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 KFX88732.1 - 0.032 14.7 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Rop PF01815.16 KFX88732.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Rop protein Glyco_hydro_18 PF00704.28 KFX88733.1 - 3.5e-43 148.5 1.9 3.5e-43 148.5 1.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX88733.1 - 6.6e-06 26.1 0.1 0.18 11.9 0.0 3.7 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KFX88733.1 - 0.0002 21.8 8.1 0.0002 21.8 8.1 4.2 3 1 0 3 3 3 1 Chitin recognition protein RTA1 PF04479.13 KFX88734.1 - 6.1e-52 176.2 10.5 8.2e-52 175.8 10.5 1.2 1 0 0 1 1 1 1 RTA1 like protein COX15-CtaA PF02628.15 KFX88735.1 - 1.8e-60 204.7 0.4 2.1e-60 204.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein HVSL PF09749.9 KFX88736.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Opy2 PF09463.10 KFX88745.1 - 1.2 9.5 13.5 1.2 9.5 5.3 3.0 1 1 1 2 2 2 0 Opy2 protein GLEYA PF10528.9 KFX88746.1 - 1.3e-29 102.5 0.4 3.4e-29 101.1 0.4 1.8 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KFX88746.1 - 1e-08 35.1 0.1 2.3e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 PA14 domain PAN_1 PF00024.26 KFX88746.1 - 1.1e-06 28.5 20.1 2.3e-05 24.3 1.9 2.8 2 1 0 2 2 2 2 PAN domain Pyr_redox_2 PF07992.14 KFX88746.1 - 5.4e-05 22.6 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PAN_4 PF14295.6 KFX88746.1 - 0.015 15.2 0.7 0.015 15.2 0.7 3.0 3 0 0 3 3 3 0 PAN domain PHO4 PF01384.20 KFX88747.1 - 3.1e-102 342.1 12.4 3.5e-102 341.9 12.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family ECF_trnsprt PF12822.7 KFX88747.1 - 0.003 17.7 6.9 0.003 17.7 6.9 2.9 2 1 0 2 2 2 1 ECF transporter, substrate-specific component Zn_clus PF00172.18 KFX88749.1 - 1.4e-08 34.7 11.6 2.2e-08 34.1 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX88749.1 - 0.00034 19.5 1.4 0.0004 19.3 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain UvrD_C PF13361.6 KFX88749.1 - 0.01 15.2 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AA_permease_2 PF13520.6 KFX88750.1 - 8.8e-54 182.9 43.1 1.6e-43 149.1 30.5 3.8 2 2 2 4 4 4 2 Amino acid permease RTA1 PF04479.13 KFX88750.1 - 5.1e-45 153.6 5.0 5.1e-45 153.6 5.0 2.8 3 1 0 3 3 3 1 RTA1 like protein AA_permease PF00324.21 KFX88750.1 - 7.5e-13 47.9 37.2 7.5e-13 47.9 37.2 2.8 2 1 0 2 2 2 1 Amino acid permease APA3_viroporin PF11289.8 KFX88750.1 - 0.024 14.2 2.0 0.062 12.8 2.0 1.6 1 0 0 1 1 1 0 Coronavirus accessory protein 3a Amidohydro_2 PF04909.14 KFX88753.1 - 6.9e-20 72.0 0.2 8.2e-20 71.8 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase APH PF01636.23 KFX88754.1 - 5.3e-09 36.4 0.0 9.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX88754.1 - 0.0001 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase adh_short_C2 PF13561.6 KFX88755.1 - 1.8e-56 191.3 3.5 2.6e-56 190.8 3.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX88755.1 - 1.1e-43 149.0 5.0 1.6e-43 148.5 5.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Hydrolase_3 PF08282.12 KFX88756.1 - 1.6e-12 47.7 0.0 1.8e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 KFX88756.1 - 2.1e-10 40.8 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase PF00702.26 KFX88756.1 - 0.001 19.4 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KFX88756.1 - 0.015 14.8 0.0 0.098 12.2 0.0 2.1 2 1 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 KFX88756.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase Alpha-amylase PF00128.24 KFX88757.1 - 1.6e-54 185.8 0.0 2.2e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KFX88757.1 - 7.2e-22 77.5 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.19 KFX88757.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V BTB PF00651.31 KFX88758.1 - 8.2e-08 32.5 1.0 1.9e-05 24.8 0.2 3.0 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_C97 PF05903.14 KFX88768.1 - 2e-34 118.6 0.0 3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFX88768.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 KFX88768.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.19 KFX88769.1 - 4.9e-11 43.0 0.1 1.1e-10 41.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 KFX88770.1 - 2e-35 122.1 0.0 4.8e-35 120.8 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain Dus PF01207.17 KFX88771.1 - 7.4e-54 182.9 0.0 8.6e-53 179.4 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KFX88771.1 - 0.021 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 KFX88771.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Na_Ca_ex PF01699.24 KFX88772.1 - 7.1e-41 139.7 39.4 1.3e-20 73.8 19.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4337 PF14235.6 KFX88772.1 - 0.68 10.0 4.2 2.1 8.4 4.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.6 KFX88772.1 - 7.9 5.4 9.4 13 4.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.10 KFX88772.1 - 9.9 6.2 8.6 24 5.0 8.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.25 KFX88773.1 - 1.2e-63 215.0 0.0 1.8e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88773.1 - 2.3e-35 122.1 0.0 6.8e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX88773.1 - 1.2e-06 28.1 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFX88773.1 - 0.00057 19.9 0.0 0.00057 19.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX88773.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFX88773.1 - 0.028 13.4 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFX88773.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GWT1 PF06423.12 KFX88774.1 - 9.1e-41 139.4 2.3 2.4e-40 138.1 2.3 1.8 1 0 0 1 1 1 1 GWT1 DUF4896 PF16237.5 KFX88774.1 - 0.054 13.3 1.9 0.59 10.0 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) DUF4818 PF16089.5 KFX88774.1 - 0.11 12.9 2.0 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) DUF1129 PF06570.11 KFX88774.1 - 0.59 9.6 2.8 0.98 8.9 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) HrpF PF06266.12 KFX88781.1 - 1.1 9.6 3.6 1.6 9.0 1.9 2.0 2 1 0 2 2 2 0 HrpF protein SurA_N_3 PF13624.6 KFX88781.1 - 1.5 8.6 8.9 3.4 7.5 8.5 1.8 2 0 0 2 2 2 0 SurA N-terminal domain Ank_2 PF12796.7 KFX88784.1 - 1.3e-60 201.9 0.4 2.9e-18 66.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX88784.1 - 4.9e-40 130.9 0.1 3.2e-05 24.0 0.0 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KFX88784.1 - 1.7e-39 132.6 0.0 6.8e-05 23.1 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KFX88784.1 - 8.3e-39 131.5 0.5 3.4e-08 33.9 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX88784.1 - 2e-30 104.5 0.2 1.2e-06 28.6 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KFX88784.1 - 0.00038 20.3 10.0 0.21 11.5 0.2 5.1 6 0 0 6 6 6 2 von Willebrand factor type A C-terminal domain FAD_binding_3 PF01494.19 KFX88785.1 - 4.3e-16 59.1 0.0 3.3e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFX88785.1 - 0.00098 19.3 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX88785.1 - 0.024 13.7 0.5 0.62 9.1 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DUF1460 PF07313.12 KFX88785.1 - 0.1 12.0 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Abhydrolase_1 PF00561.20 KFX88786.1 - 1.7e-18 67.2 0.1 2.6e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX88786.1 - 4.3e-17 63.4 0.0 6.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX88786.1 - 9e-06 25.1 0.0 9.7e-05 21.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFX88786.1 - 0.0015 18.3 0.0 0.45 10.3 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF5083 PF16890.5 KFX88786.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) MFS_1 PF07690.16 KFX88787.1 - 8.5e-37 126.9 67.3 1.1e-32 113.3 52.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX88787.1 - 2.1e-09 37.2 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX88787.1 - 1.6e-07 30.6 0.1 3e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX88787.1 - 0.00017 20.8 1.5 0.00025 20.3 0.1 1.9 3 0 0 3 3 3 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFX88787.1 - 0.00041 19.8 0.1 0.0008 18.9 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KFX88788.1 - 1.6e-12 47.0 0.1 2.6e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phospholip_A2_3 PF09056.11 KFX88789.1 - 5e-40 136.6 5.7 6.8e-40 136.2 5.7 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 GOLGA2L5 PF15070.6 KFX88789.1 - 0.21 10.2 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 CEP19 PF14933.6 KFX88790.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 CEP19-like protein MMR_HSR1 PF01926.23 KFX88791.1 - 6.3e-08 32.7 0.4 1.5e-07 31.5 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFX88791.1 - 5.2e-07 29.9 4.5 0.012 15.7 0.3 2.6 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KFX88791.1 - 0.00028 20.3 0.1 0.00045 19.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KFX88791.1 - 0.00063 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 KFX88791.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KFX88791.1 - 0.016 14.5 0.3 0.078 12.2 0.3 2.1 1 1 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 KFX88791.1 - 0.03 14.2 1.0 0.2 11.6 1.0 2.2 1 1 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFX88791.1 - 0.041 14.2 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFX88791.1 - 0.15 12.1 0.3 2 8.5 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFX88791.1 - 0.16 11.7 0.9 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX88791.1 - 0.16 12.5 1.9 0.39 11.2 0.2 2.2 2 0 0 2 2 2 0 ABC transporter Abhydrolase_3 PF07859.13 KFX88793.1 - 1.1e-25 90.8 0.0 1.4e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX88793.1 - 7.2e-08 31.7 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KFX88793.1 - 0.036 13.3 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX88793.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KFX88793.1 - 0.18 10.6 0.0 6.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Sugar_tr PF00083.24 KFX88794.1 - 4.3e-31 108.3 24.2 8.3e-31 107.3 24.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Phosphodiest PF01663.22 KFX88794.1 - 3.6e-27 95.9 0.0 6.9e-27 95.0 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KFX88794.1 - 4e-14 52.3 29.9 5.7e-13 48.5 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.22 KFX88794.1 - 7.5e-07 29.4 0.1 1.5e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 KFX88794.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HD_4 PF13328.6 KFX88794.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain Phage_holin_3_6 PF07332.11 KFX88794.1 - 7.9 6.6 13.0 3.2 7.8 0.0 3.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PhyH PF05721.13 KFX88795.1 - 6e-29 101.8 0.1 7.8e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFX88795.1 - 0.00057 20.3 0.1 0.0015 18.9 0.1 1.8 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KFX88795.1 - 0.076 13.9 0.2 0.23 12.4 0.1 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3836 PF12930.7 KFX88795.1 - 0.14 11.9 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Zn_clus PF00172.18 KFX88796.1 - 8e-09 35.5 9.7 1.3e-08 34.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BHD_2 PF10404.9 KFX88796.1 - 0.09 13.7 0.0 19 6.3 0.0 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Glyco_hydro_88 PF07470.13 KFX88797.1 - 5.1e-76 256.0 1.2 6.6e-76 255.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFX88797.1 - 0.0014 17.2 0.0 0.0019 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Porin_3 PF01459.22 KFX88801.1 - 4.4e-71 239.5 6.0 5.5e-71 239.2 6.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin His_Phos_1 PF00300.22 KFX88802.1 - 3.4e-33 115.0 0.0 4.4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Utp21 PF04192.12 KFX88807.1 - 1e-75 254.3 0.0 1.5e-75 253.7 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KFX88807.1 - 6.4e-17 61.6 21.0 9.4e-06 26.3 0.1 9.1 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88807.1 - 4.4e-14 52.5 0.0 0.0011 19.2 0.0 6.4 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFX88807.1 - 5.4e-07 28.5 0.0 1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 KFX88807.1 - 0.00011 21.1 0.1 0.1 11.2 0.0 3.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KFX88807.1 - 0.019 14.9 0.1 0.41 10.5 0.1 2.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 KFX88807.1 - 0.023 13.8 0.1 0.079 12.0 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 KFX88807.1 - 0.033 13.1 0.0 0.71 8.8 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPT PF03151.16 KFX88811.1 - 4e-06 26.4 19.2 1.4e-05 24.6 19.2 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRPA PF05745.11 KFX88811.1 - 0.081 12.9 0.2 0.081 12.9 0.2 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tuberculin PF12198.8 KFX88811.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Theoretical tuberculin protein UPF0139 PF03669.13 KFX88811.1 - 0.16 11.8 1.2 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) zf-C2H2_aberr PF17017.5 KFX88813.1 - 0.019 15.1 2.4 0.043 14.0 0.1 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KFX88813.1 - 0.034 15.0 5.9 4.2 8.5 1.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX88813.1 - 0.11 13.0 10.8 1.9 9.1 1.3 3.1 2 1 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 KFX88814.1 - 1.2e-20 74.1 0.0 2e-20 73.4 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 BAG PF02179.16 KFX88831.1 - 7.1e-20 71.2 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFX88831.1 - 0.0025 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFX88831.1 - 0.0081 16.7 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain AP3D1 PF06375.11 KFX88831.1 - 1.5 9.0 8.1 3 8.1 8.1 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Apt1 PF10351.9 KFX88834.1 - 9.5 5.0 8.7 13 4.5 8.7 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF4246 PF14033.6 KFX88835.1 - 2.3e-174 580.8 0.3 2.9e-174 580.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KFX88835.1 - 0.017 15.6 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ABC2_membrane PF01061.24 KFX88836.1 - 4.3e-39 134.1 19.9 8.5e-39 133.1 19.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFX88836.1 - 2.7e-25 89.5 0.1 1.9e-24 86.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFX88836.1 - 2.5e-05 24.3 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFX88836.1 - 4.7e-05 22.7 31.5 0.00036 19.8 31.5 2.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 KFX88836.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KFX88836.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KFX88836.1 - 0.018 14.9 0.1 0.052 13.4 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KFX88836.1 - 0.029 14.6 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFX88836.1 - 0.032 14.3 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KFX88836.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFX88836.1 - 0.061 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFX88836.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 KFX88836.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 KFX88836.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KFX88836.1 - 0.32 10.9 3.8 0.4 10.6 0.1 3.0 3 0 0 3 3 3 0 CDR ABC transporter hEGF PF12661.7 KFX88836.1 - 4.8 8.0 17.2 8.3 7.2 0.3 4.5 3 0 0 3 3 3 0 Human growth factor-like EGF Aminotran_1_2 PF00155.21 KFX88837.1 - 4.8e-38 131.3 0.0 6.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX88837.1 - 1.1e-06 27.7 0.0 2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 KFX88837.1 - 2.5e-06 26.3 0.0 3.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFX88837.1 - 2.8e-05 23.3 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX88837.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KFX88837.1 - 0.0016 17.4 0.2 0.0037 16.2 0.2 1.5 1 1 0 1 1 1 1 Allinase DnaB_2 PF07261.11 KFX88837.1 - 0.02 14.6 0.0 14 5.5 0.0 3.2 3 0 0 3 3 3 0 Replication initiation and membrane attachment SET PF00856.28 KFX88838.1 - 1.1e-08 35.7 0.2 7.9e-08 32.9 0.2 2.0 1 1 0 1 1 1 1 SET domain MRP-S26 PF14943.6 KFX88839.1 - 0.023 14.6 4.6 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 NGP1NT PF08153.12 KFX88840.1 - 3.3e-46 156.6 0.1 5.4e-46 156.0 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFX88840.1 - 7.2e-17 61.5 0.0 5.1e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX88840.1 - 0.00023 20.7 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFX88840.1 - 0.00074 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFX88840.1 - 0.0015 18.1 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX88840.1 - 0.01 15.4 0.0 0.42 10.1 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFX88840.1 - 0.019 15.0 5.3 1.3 9.1 0.0 4.0 3 1 1 4 4 4 0 Dynamin family AAA_16 PF13191.6 KFX88840.1 - 0.17 12.2 0.4 0.97 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DNA_pol_phi PF04931.13 KFX88840.1 - 0.73 7.9 15.3 1.1 7.2 15.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi HBS1_N PF08938.10 KFX88840.1 - 2.6 8.4 11.9 3.6 8.0 0.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus AA_permease_2 PF13520.6 KFX88842.1 - 1.1e-60 205.7 25.4 1.3e-60 205.5 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX88842.1 - 3e-12 45.9 22.8 4e-12 45.5 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease COPI_assoc PF08507.10 KFX88842.1 - 0.047 13.7 0.2 0.047 13.7 0.2 2.5 2 0 0 2 2 2 0 COPI associated protein Abhydro_lipase PF04083.16 KFX88846.1 - 2.3e-17 62.3 0.0 4.2e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DUF3328 PF11807.8 KFX88846.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) ADH_N PF08240.12 KFX88847.1 - 1.7e-09 37.5 0.5 3e-09 36.7 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX88847.1 - 3.7e-06 26.9 0.0 4.8e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFX88847.1 - 0.017 15.1 1.6 0.13 12.2 1.6 2.3 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KFX88847.1 - 0.05 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 KFX88847.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFX88847.1 - 0.14 13.3 0.0 0.26 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Chromo PF00385.24 KFX88849.1 - 1.4 8.9 5.7 0.48 10.4 2.8 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.13 KFX88850.1 - 1.1 8.4 5.5 1.6 7.9 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Erv26 PF04148.13 KFX88851.1 - 2.4e-87 292.0 1.6 2.8e-87 291.8 1.6 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM43 PF07787.12 KFX88851.1 - 0.41 10.0 3.4 0.61 9.4 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Methyltransf_11 PF08241.12 KFX88852.1 - 1.3e-10 41.8 0.0 2.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX88852.1 - 8.6e-10 39.2 0.0 2.2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 KFX88852.1 - 5.5e-09 36.7 1.7 9.5e-09 35.9 1.7 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 KFX88852.1 - 7.5e-05 23.4 0.4 0.00052 20.7 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KFX88852.1 - 0.0001 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFX88852.1 - 0.00043 19.7 0.0 0.00089 18.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KFX88852.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX88852.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX88852.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF1640 PF07798.11 KFX88853.1 - 1.4e-52 178.3 11.0 1.8e-52 177.9 11.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CENP-O PF09496.10 KFX88853.1 - 0.0065 16.5 0.8 0.01 15.8 0.8 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component OEP PF02321.18 KFX88853.1 - 0.31 10.8 7.8 3.1 7.6 0.4 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein MnmE_helical PF12631.7 KFX88853.1 - 0.41 10.8 4.6 0.28 11.3 2.6 1.6 2 0 0 2 2 2 0 MnmE helical domain cwf21 PF08312.12 KFX88853.1 - 0.87 9.8 5.8 1.1 9.4 4.3 2.1 2 1 0 2 2 2 0 cwf21 domain eIF2_C PF09173.11 KFX88854.1 - 8.4e-35 118.9 0.5 2.4e-34 117.4 0.5 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFX88854.1 - 3.7e-22 78.8 0.3 3.3e-21 75.7 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFX88854.1 - 1.4e-10 41.4 0.5 3e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFX88854.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX88854.1 - 0.086 12.7 0.2 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFX88854.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Peptidase_C12 PF01088.21 KFX88856.1 - 9.4e-55 185.6 0.0 1.1e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DDE_1 PF03184.19 KFX88861.1 - 3.9e-12 46.2 0.1 8.9e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease GA-like PF17573.2 KFX88861.1 - 0.19 11.7 0.4 0.79 9.7 0.4 2.1 1 0 0 1 1 1 0 GA-like domain rve PF00665.26 KFX88862.1 - 4.1e-14 52.8 0.0 8.9e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KFX88862.1 - 0.043 13.6 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Trypan_PARP PF05887.11 KFX88862.1 - 0.45 10.5 19.8 0.87 9.6 3.5 2.7 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Rib_recp_KP_reg PF05104.12 KFX88862.1 - 3.9 8.5 8.5 0.62 11.1 2.0 2.1 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region LRR_6 PF13516.6 KFX88873.1 - 1.9e-11 43.0 13.1 8.3e-05 22.3 0.0 8.3 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.7 KFX88873.1 - 3.2e-09 36.5 0.9 1.3e-08 34.6 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFX88873.1 - 3.4e-06 26.8 0.8 1.2e-05 25.1 0.8 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KFX88873.1 - 4.4e-05 23.7 11.8 0.18 12.3 0.0 6.7 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFX88873.1 - 0.083 13.5 16.7 2 9.3 0.3 7.5 9 1 0 9 9 9 0 Leucine Rich Repeat Sin3a_C PF16879.5 KFX88876.1 - 9.2e-67 225.8 5.7 9.2e-67 225.8 5.7 3.3 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KFX88876.1 - 4.2e-44 148.4 8.3 8.7e-18 64.2 0.0 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KFX88876.1 - 2.5e-38 130.1 0.0 7.1e-38 128.6 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor DLIC PF05783.11 KFX88876.1 - 0.071 11.9 0.9 0.15 10.9 0.9 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Pollen_allerg_1 PF01357.21 KFX88876.1 - 0.16 12.0 0.2 0.83 9.7 0.2 2.1 2 0 0 2 2 2 0 Pollen allergen Fasciclin PF02469.22 KFX88877.1 - 2.2e-05 24.7 0.0 4.3e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain FAD_binding_2 PF00890.24 KFX88878.1 - 2.1e-82 277.4 0.1 3.5e-82 276.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KFX88878.1 - 6.9e-23 80.6 0.1 2.1e-21 75.8 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KFX88878.1 - 9.9e-13 48.4 0.2 3.8e-12 46.5 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX88878.1 - 2e-09 37.3 0.4 5.8e-09 35.8 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX88878.1 - 1.4e-07 31.1 0.2 1.3e-06 27.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88878.1 - 2.8e-07 30.7 1.6 1.2e-06 28.7 0.2 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX88878.1 - 5.6e-05 22.5 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX88878.1 - 0.0001 21.7 0.4 0.022 14.0 0.1 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KFX88878.1 - 0.00054 18.8 4.3 0.015 14.0 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KFX88878.1 - 0.0021 17.2 1.8 0.26 10.3 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KFX88878.1 - 0.01 15.2 0.6 0.52 9.5 0.1 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFX88878.1 - 0.019 14.2 1.1 0.054 12.7 0.6 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KFX88878.1 - 0.023 15.2 3.1 3.8 8.1 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IF2_N PF04760.15 KFX88878.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Ribosomal_60s PF00428.19 KFX88878.1 - 7 7.3 9.3 15 6.2 9.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hydro_76 PF03663.14 KFX88879.1 - 1.5e-19 70.8 2.5 5.2e-12 46.0 0.0 3.7 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX88879.1 - 0.027 13.5 0.0 0.085 11.9 0.0 1.8 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 DHHC PF01529.20 KFX88880.1 - 1.2e-29 103.2 7.8 1.2e-29 103.2 7.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase MgsA_C PF12002.8 KFX88886.1 - 6.3e-59 198.7 0.0 9.9e-59 198.0 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFX88886.1 - 4.2e-22 78.3 0.1 9.3e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFX88886.1 - 2.7e-12 47.3 0.0 6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFX88886.1 - 4e-08 33.2 0.0 7.8e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFX88886.1 - 6.9e-06 25.6 0.1 0.04 13.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KFX88886.1 - 6.2e-05 22.8 0.1 0.0021 17.8 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KFX88886.1 - 8.8e-05 23.0 0.3 0.02 15.3 0.1 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFX88886.1 - 0.00021 21.3 0.1 0.016 15.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX88886.1 - 0.0024 18.1 0.2 0.0074 16.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFX88886.1 - 0.0054 16.6 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFX88886.1 - 0.012 16.0 0.0 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFX88886.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KFX88886.1 - 0.022 14.0 0.0 0.045 13.0 0.0 1.3 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KFX88886.1 - 0.052 13.3 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KFX88886.1 - 0.058 13.4 0.1 6.4 6.7 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KFX88886.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFX88886.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-ribbon_3 PF13248.6 KFX88886.1 - 0.11 11.9 0.5 0.31 10.5 0.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain AAA_29 PF13555.6 KFX88886.1 - 0.13 12.0 0.0 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 KFX88886.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KFX88886.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Glyco_hydro_10 PF00331.20 KFX88887.1 - 2.2e-103 345.8 0.0 2.6e-103 345.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 LEA_6 PF10714.9 KFX88887.1 - 0.03 14.4 1.3 0.03 14.4 1.3 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Beta-prism_lec PF16458.5 KFX88887.1 - 0.18 11.8 2.6 0.22 11.5 0.9 1.9 2 0 0 2 2 2 0 Beta-prism lectin DUF1771 PF08590.10 KFX88903.1 - 4.5e-15 55.8 9.7 1.8e-14 53.8 9.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KFX88903.1 - 3e-09 36.6 6.5 4.9e-06 26.4 0.6 3.0 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KFX88903.1 - 2.7e-07 30.8 0.0 8.4e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KFX88903.1 - 2e-06 27.5 0.6 0.0061 16.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFX88903.1 - 2.5e-05 24.0 8.9 0.0023 17.7 0.4 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFX88903.1 - 0.00018 21.9 4.4 0.29 11.7 0.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 KFX88903.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 HBS1 N-terminus Torus PF16131.5 KFX88903.1 - 0.078 13.7 2.9 2.1 9.1 0.6 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KFX88903.1 - 0.11 12.7 5.1 3.7 7.8 0.6 2.4 1 1 1 2 2 2 0 Zinc-finger containing family CPSase_L_D2 PF02786.17 KFX88904.1 - 7.5e-82 273.9 0.1 1.3e-81 273.2 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KFX88904.1 - 1e-65 221.2 0.0 2.3e-65 220.1 0.0 1.6 2 0 0 2 2 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KFX88904.1 - 8.5e-36 122.9 0.0 1.8e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFX88904.1 - 1.2e-27 96.2 0.0 6e-27 93.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KFX88904.1 - 8.1e-26 91.1 0.0 1.8e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KFX88904.1 - 1.4e-16 60.1 4.7 4.5e-16 58.4 4.5 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX88904.1 - 2.1e-10 40.5 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KFX88904.1 - 5.8e-08 32.4 2.1 1.9e-07 30.8 0.3 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 KFX88904.1 - 9.5e-08 31.8 0.1 2e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KFX88904.1 - 1.2e-05 25.0 0.0 3.7e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFX88904.1 - 1.3e-05 25.3 0.2 4.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KFX88904.1 - 0.0014 18.0 0.0 0.0032 16.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KFX88904.1 - 0.0016 18.0 0.1 0.0082 15.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 KFX88904.1 - 0.0045 16.2 0.6 0.034 13.4 0.3 2.1 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2118 PF09891.9 KFX88904.1 - 0.011 15.7 0.7 0.027 14.4 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_YheCD PF14398.6 KFX88904.1 - 0.012 14.9 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp GARS_A PF01071.19 KFX88904.1 - 0.017 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 KFX88904.1 - 0.041 14.6 0.9 0.21 12.3 0.8 2.2 1 1 0 1 1 1 0 HlyD family secretion protein QRPTase_N PF02749.16 KFX88904.1 - 0.056 13.5 0.4 0.44 10.6 0.2 2.5 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Ribosomal_L5_C PF00673.21 KFX88906.1 - 1.8e-21 76.1 0.0 2.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFX88906.1 - 2.3e-19 69.5 0.0 4.8e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 LSM PF01423.22 KFX88907.1 - 1.7e-18 66.1 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 KFX88908.1 - 1.9e-35 121.3 0.0 2.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Na_Ca_ex PF01699.24 KFX88909.1 - 2e-51 173.9 44.1 2e-26 92.8 20.5 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Vpu PF00558.19 KFX88909.1 - 1.4 8.8 3.8 5.4 6.9 0.0 3.1 3 0 0 3 3 3 0 Vpu protein HemY_N PF07219.13 KFX88909.1 - 2.5 8.3 4.6 41 4.4 1.6 3.0 2 0 0 2 2 2 0 HemY protein N-terminus IncE PF17627.2 KFX88909.1 - 8.7 6.4 10.9 13 5.8 3.7 2.5 2 0 0 2 2 2 0 Inclusion membrane protein E Cnd2 PF05786.14 KFX88910.1 - 0 1075.8 1.7 0 1075.6 1.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KFX88910.1 - 0.012 15.8 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MGS PF02142.22 KFX88912.1 - 6.3e-24 84.0 0.0 1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 MGS-like domain AICARFT_IMPCHas PF01808.18 KFX88912.1 - 1.6e-16 60.6 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme ACC_epsilon PF13822.6 KFX88914.1 - 2.5 8.8 7.6 4.7 8.0 7.6 1.7 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Clathrin PF00637.20 KFX88915.1 - 6.8e-206 674.4 40.9 1.3e-33 115.8 3.0 7.6 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFX88915.1 - 2.6e-34 115.9 0.1 2.4e-07 30.7 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFX88915.1 - 1.6e-33 114.4 2.3 4.1e-33 113.1 0.3 2.9 2 1 1 3 3 3 1 Clathrin-H-link TPR_7 PF13176.6 KFX88915.1 - 7.9e-05 22.4 3.3 40 4.6 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Clathrin-link PF09268.10 KFX88915.1 - 0.00044 19.5 0.5 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_8 PF13181.6 KFX88915.1 - 0.00046 20.2 3.4 1.9 8.9 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Vps39_1 PF10366.9 KFX88915.1 - 0.0058 16.9 13.0 14 6.1 0.0 7.1 5 2 3 8 8 8 1 Vacuolar sorting protein 39 domain 1 Cytidylate_kin2 PF13189.6 KFX88915.1 - 0.014 15.5 0.0 6.2 6.9 0.0 3.0 2 0 0 2 2 2 0 Cytidylate kinase-like family TPR_12 PF13424.6 KFX88915.1 - 0.019 15.2 0.8 83 3.6 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88915.1 - 0.023 15.5 14.0 0.94 10.5 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX88915.1 - 0.039 13.8 1.9 14 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFX88915.1 - 1.4 7.9 11.3 0.81 8.7 0.5 4.0 5 0 0 5 5 5 0 Coatomer WD associated region TPR_2 PF07719.17 KFX88915.1 - 6.2 7.2 11.3 36 4.8 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Atg31 PF09795.9 KFX88920.1 - 0.076 13.0 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 31 zf-ANAPC11 PF12861.7 KFX88921.1 - 3.3e-45 152.1 11.8 3.9e-45 151.8 11.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFX88921.1 - 1.3e-21 76.6 12.3 2e-21 76.0 12.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX88921.1 - 1.1e-07 32.1 16.3 2.3e-06 27.8 16.3 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX88921.1 - 1.9e-05 24.6 8.9 0.00012 22.0 5.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFX88921.1 - 0.00013 21.7 14.9 0.00056 19.7 14.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX88921.1 - 0.0011 18.8 12.9 0.022 14.6 12.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFX88921.1 - 0.0015 18.3 2.7 0.0015 18.3 2.7 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFX88921.1 - 0.002 18.3 16.8 0.035 14.3 16.8 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFX88921.1 - 0.0023 17.5 11.8 0.02 14.5 11.8 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KFX88921.1 - 0.013 15.3 13.5 0.013 15.3 13.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFX88921.1 - 0.015 15.1 5.3 0.025 14.4 5.3 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFX88921.1 - 0.023 14.8 9.8 0.023 14.8 9.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING YacG PF03884.14 KFX88921.1 - 0.083 12.6 6.1 0.18 11.6 0.2 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-HIT PF04438.16 KFX88921.1 - 0.093 12.6 1.0 0.093 12.6 1.0 2.4 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 KFX88921.1 - 0.096 12.5 4.3 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KFX88921.1 - 0.18 11.6 12.3 0.52 10.1 9.0 2.9 2 1 0 2 2 2 0 RING-like zinc finger zf-C2H2_9 PF16293.5 KFX88921.1 - 0.19 11.6 4.6 2 8.4 0.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Prok-RING_4 PF14447.6 KFX88921.1 - 0.34 10.8 14.4 1.8 8.5 10.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF2256 PF10013.9 KFX88921.1 - 0.4 10.8 0.2 0.4 10.8 0.2 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) UBZ_FAAP20 PF15750.5 KFX88921.1 - 0.42 10.6 5.9 1.8 8.6 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zf-RING_5 PF14634.6 KFX88921.1 - 0.99 9.4 18.0 35 4.5 18.4 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KFX88921.1 - 1.5 9.2 13.2 3.4 8.0 11.4 2.2 1 1 1 2 2 2 0 RING-like domain Opy2 PF09463.10 KFX88921.1 - 1.8 8.9 11.2 7.4 7.0 6.3 2.5 2 1 0 2 2 2 0 Opy2 protein RINGv PF12906.7 KFX88921.1 - 2.2 8.5 13.2 5 7.3 12.3 2.2 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.7 KFX88921.1 - 3.3 7.8 12.7 5.1 7.2 5.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon Rhodanese PF00581.20 KFX88922.1 - 2.9e-17 63.1 0.0 6.5e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.20 KFX88923.1 - 6.9e-28 96.4 1.9 5.2e-27 93.6 1.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFX88923.1 - 2.8e-23 81.2 0.0 4.6e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXMRP1_C_core PF12235.8 KFX88923.1 - 4.1 8.0 9.2 6.8 7.3 9.2 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Cyclin_N PF00134.23 KFX88926.1 - 2.6e-35 120.9 0.3 5.5e-35 119.9 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX88926.1 - 1.7e-12 47.4 0.2 4.4e-12 46.1 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain PIG-U PF06728.13 KFX88932.1 - 3.2e-124 414.8 28.8 3.8e-124 414.6 28.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PIRT PF15099.6 KFX88932.1 - 0.021 14.4 0.4 0.048 13.2 0.4 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family 8TM_micro PF17028.5 KFX88932.1 - 0.037 13.7 9.7 0.083 12.6 9.7 1.5 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 KFX88933.1 - 3.2e-121 404.0 0.0 7.4e-121 402.9 0.0 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 KFX88933.1 - 0.00021 21.6 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFX88933.1 - 0.0098 16.3 0.0 0.041 14.3 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KFX88933.1 - 0.071 12.3 12.8 0.15 11.2 12.8 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LIG3_BRCT PF16759.5 KFX88933.1 - 0.22 11.8 0.2 0.67 10.3 0.2 1.9 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain RNase_H2_suC PF08615.11 KFX88933.1 - 9.4 6.4 6.8 53 4.0 6.7 2.4 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WLM PF08325.10 KFX88935.1 - 5.7e-28 98.3 0.5 5.7e-28 98.3 0.5 2.1 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.17 KFX88935.1 - 6.4e-08 32.9 1.0 1.2e-07 32.0 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Siva PF05458.12 KFX88935.1 - 0.032 13.9 3.6 0.052 13.2 3.6 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) YdjO PF14169.6 KFX88935.1 - 0.084 12.6 0.1 0.084 12.6 0.1 3.5 1 1 2 3 3 3 0 Cold-inducible protein YdjO MIR PF02815.19 KFX88935.1 - 0.12 12.2 0.1 0.12 12.2 0.1 1.5 2 0 0 2 2 2 0 MIR domain DZR PF12773.7 KFX88935.1 - 0.28 11.3 2.4 2.5 8.2 2.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon KH_1 PF00013.29 KFX88936.1 - 2.1e-43 146.0 3.6 2.8e-18 65.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFX88936.1 - 3.4e-12 46.0 5.1 0.004 16.9 0.2 3.5 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KFX88936.1 - 2.9e-05 24.0 0.0 0.0077 16.2 0.0 2.6 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_4 PF13083.6 KFX88936.1 - 5.6e-05 22.9 0.8 1.2 9.0 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KFX88936.1 - 0.0016 18.5 8.2 0.21 11.7 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain Astro_capsid_p2 PF16580.5 KFX88936.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike CENP-K PF11802.8 KFX88938.1 - 1.7e-06 27.9 7.5 0.0045 16.6 0.0 3.1 2 1 0 3 3 3 2 Centromere-associated protein K FlgN PF05130.12 KFX88938.1 - 0.22 12.0 13.1 0.36 11.3 0.9 2.9 3 0 0 3 3 3 0 FlgN protein Spc7 PF08317.11 KFX88938.1 - 0.82 8.5 8.7 1.4 7.7 1.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KFX88938.1 - 0.98 9.6 4.5 9.6 6.4 0.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.21 KFX88938.1 - 1.1 8.8 8.9 0.91 9.0 1.5 2.4 2 0 0 2 2 2 0 Intermediate filament protein BAR PF03114.18 KFX88938.1 - 1.4 8.5 10.0 3.2 7.3 5.6 2.8 2 1 0 2 2 2 0 BAR domain DUF4446 PF14584.6 KFX88938.1 - 1.8 8.6 5.9 2.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Abhydrolase_1 PF00561.20 KFX88939.1 - 3.2e-11 43.4 0.0 5.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX88939.1 - 1.6e-07 30.9 0.0 3.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX88939.1 - 0.047 13.1 0.0 0.36 10.3 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF4110 PF13422.6 KFX88940.1 - 2.5e-28 98.0 0.2 2.5e-28 98.0 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KFX88940.1 - 3.8e-27 94.1 10.9 2.9e-07 30.4 0.0 6.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFX88940.1 - 3.7e-24 84.5 16.9 3.2e-07 30.5 0.2 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFX88940.1 - 1.1e-17 63.6 2.1 0.00028 21.1 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KFX88940.1 - 3.1e-16 58.9 2.9 1.3e-06 28.2 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KFX88940.1 - 2.5e-15 55.8 0.6 3.9e-05 23.1 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFX88940.1 - 6.4e-12 45.0 2.7 0.19 11.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif MCPVI PF02993.14 KFX88940.1 - 0.047 13.5 1.8 0.12 12.2 1.2 1.9 2 0 0 2 2 2 0 Minor capsid protein VI Proteasome PF00227.26 KFX88941.1 - 1.7e-47 161.4 0.2 2.2e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFX88941.1 - 3e-13 48.9 1.3 3e-13 48.9 1.3 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 KFX88942.1 - 7.5e-11 41.9 0.1 8.8e-10 38.4 0.0 2.6 2 1 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 KFX88942.1 - 0.00094 19.4 0.0 0.0026 18.0 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DnaJ_C PF01556.18 KFX88943.1 - 4.6e-39 133.9 0.4 8e-39 133.1 0.4 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFX88943.1 - 7.7e-20 70.8 1.7 2e-19 69.4 1.7 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX88943.1 - 1.7e-15 57.1 19.7 1.7e-15 57.1 19.7 2.5 2 0 0 2 2 2 1 DnaJ central domain Fungal_trans PF04082.18 KFX88943.1 - 5.4e-12 45.3 0.0 9.8e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88943.1 - 3.8e-07 30.1 8.5 3.8e-07 30.1 8.5 3.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Anti-TRAP PF15777.5 KFX88943.1 - 5.4 7.1 17.3 0.71 9.9 3.1 2.9 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein WD40 PF00400.32 KFX88944.1 - 6.9e-05 23.5 0.5 3 8.9 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFX88944.1 - 0.05 13.7 0.0 0.67 10.0 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region URO-D PF01208.17 KFX88946.1 - 9.1e-125 416.4 0.0 1e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.11 KFX88946.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Ribosomal_L10 PF00466.20 KFX88947.1 - 7.9e-23 80.5 0.0 1.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KFX88947.1 - 7.3e-22 77.2 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KFX88947.1 - 1.3e-13 51.3 5.0 1.7e-13 51.0 2.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.21 KFX88948.1 - 4.7e-50 170.2 0.2 1e-49 169.2 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX88948.1 - 8.5e-47 159.9 4.1 1.6e-46 158.9 4.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFX88948.1 - 5.2e-19 68.6 0.0 1.6e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFX88948.1 - 2.6e-08 34.2 0.0 6.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II NAD_binding_4 PF07993.12 KFX88948.1 - 0.023 13.9 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein RPN1_RPN2_N PF17781.1 KFX88948.1 - 0.087 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain AAA_14 PF13173.6 KFX88948.1 - 0.16 12.0 0.1 0.85 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain FMN_red PF03358.15 KFX88949.1 - 9.5e-11 41.7 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX88949.1 - 7.5e-05 22.5 0.0 9.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFX88949.1 - 0.00098 19.4 0.0 0.0098 16.1 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin zf-HC5HC2H_2 PF13832.6 KFX88950.1 - 7.4e-19 67.9 1.2 7.4e-19 67.9 1.2 4.2 4 0 0 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.18 KFX88950.1 - 5e-14 52.2 0.1 9.6e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KFX88950.1 - 6.3e-14 52.0 3.8 6.3e-14 52.0 3.8 4.7 4 1 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 KFX88950.1 - 3e-11 43.0 54.1 2.6e-06 27.2 6.7 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KFX88950.1 - 1.1e-08 34.5 3.4 1.1e-08 34.5 3.4 5.2 6 0 0 6 6 6 1 PHD-finger WD40 PF00400.32 KFX88951.1 - 8.2e-19 67.6 0.0 3.4e-08 34.0 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88951.1 - 3.8e-09 36.7 0.0 0.00018 21.8 0.0 2.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX88951.1 - 4.1e-05 22.4 0.1 0.028 13.1 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFX88951.1 - 0.00015 20.8 0.0 0.0057 15.7 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFX88951.1 - 0.034 13.7 0.5 0.18 11.4 0.5 1.9 1 1 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.6 KFX88951.1 - 0.1 11.9 0.0 7.5 5.8 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Sel1 PF08238.12 KFX88953.1 - 1.3e-11 44.7 7.2 0.0014 19.3 0.0 3.8 3 0 0 3 3 3 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KFX88954.1 - 1.8e-84 283.0 0.0 2.9e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFX88954.1 - 1.8e-28 98.7 0.1 1.3e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.20 KFX88955.1 - 8.8e-106 353.9 22.7 1.2e-105 353.4 22.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFX88955.1 - 2.2e-09 36.9 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFX88955.1 - 0.013 15.9 2.5 0.013 15.9 2.5 3.5 3 1 1 4 4 4 0 Molybdate transporter of MFS superfamily VRR_NUC PF08774.11 KFX88956.1 - 5.6e-26 90.7 0.0 1.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 KFX88957.1 - 7.3e-15 54.4 0.0 1.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 KFX88958.1 - 3e-30 104.0 0.0 5.1e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFX88958.1 - 4.7e-15 55.5 0.2 7e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFX88958.1 - 0.03 14.3 0.1 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 KFX88958.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair RabGAP-TBC PF00566.18 KFX88959.1 - 8.5e-31 107.3 0.0 9.5e-26 90.8 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.6 KFX88959.1 - 0.085 13.3 2.2 0.87 10.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) 7tm_2 PF00002.24 KFX88960.1 - 8.7e-07 28.5 16.8 8.7e-07 28.5 16.8 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) OGG_N PF07934.12 KFX88961.1 - 1.3e-35 122.1 0.0 2.3e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KFX88961.1 - 2.2e-15 57.0 0.0 3.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFX88961.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 KFX88962.1 - 2.3e-31 107.4 0.7 1.8e-12 46.9 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX88962.1 - 7.9e-08 32.1 0.0 0.081 12.8 0.0 3.5 3 0 0 3 3 3 3 Occluded RNA-recognition motif SF3b1 PF08920.10 KFX88963.1 - 2.7e-29 102.1 5.3 2.7e-29 102.1 5.3 2.1 2 1 0 2 2 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KFX88963.1 - 3.5e-12 46.6 1.0 0.012 16.1 0.0 7.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KFX88963.1 - 3e-09 37.2 11.6 0.21 12.0 0.1 8.1 5 3 5 10 10 10 3 HEAT repeats HEAT PF02985.22 KFX88963.1 - 2.2e-07 30.5 10.2 1.5 9.3 0.1 9.1 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KFX88963.1 - 0.00013 22.5 0.6 1.5 9.4 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFX88963.1 - 0.00014 20.6 0.4 0.052 12.1 0.0 3.0 3 0 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KFX88963.1 - 0.00043 20.0 0.4 1.2 8.7 0.0 4.1 4 1 0 5 5 5 2 NUC173 domain DUF3385 PF11865.8 KFX88963.1 - 0.0005 20.0 0.8 0.064 13.2 0.1 4.6 4 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 KFX88963.1 - 0.0044 17.0 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KFX88963.1 - 0.011 15.4 0.0 0.91 9.0 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal DRIM PF07539.12 KFX88963.1 - 0.091 11.0 0.1 4.8 5.4 0.0 3.4 2 1 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 KFX88963.1 - 0.14 11.3 0.0 9.8 5.2 0.0 3.2 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Rho_N PF07498.12 KFX88966.1 - 0.003 17.5 0.3 1.1 9.2 0.0 3.3 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain STALD PF18185.1 KFX88966.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family AAT PF03417.16 KFX88966.1 - 0.18 11.5 0.2 0.46 10.1 0.1 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase SAP PF02037.27 KFX88966.1 - 0.33 10.8 1.6 77 3.2 0.5 3.8 3 1 0 3 3 3 0 SAP domain Claudin_2 PF13903.6 KFX88968.1 - 0.66 9.7 4.9 0.99 9.1 0.5 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction F-box-like PF12937.7 KFX88969.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like Solute_trans_a PF03619.16 KFX88971.1 - 7.1e-58 196.2 13.7 9.2e-58 195.8 13.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Sulf_transp PF04143.14 KFX88971.1 - 0.0058 16.2 2.4 0.075 12.6 0.1 2.4 2 0 0 2 2 2 2 Sulphur transport Mad3_BUB1_I PF08311.12 KFX88988.1 - 1.1e-42 145.0 0.0 2.3e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFX88988.1 - 3.1e-09 36.6 0.0 1.4e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KFX88988.1 - 1.5e-05 25.0 0.0 4.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 BUD22 PF09073.10 KFX88988.1 - 0.0017 17.8 24.5 0.003 17.0 24.5 1.3 1 0 0 1 1 1 1 BUD22 Pkinase_Tyr PF07714.17 KFX88988.1 - 0.0043 16.4 0.1 0.013 14.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX88988.1 - 0.0084 16.1 0.1 0.0084 16.1 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX88988.1 - 0.03 13.7 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 KFX88988.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Indigoidine_A PF04227.12 KFX88989.1 - 8.7e-121 402.8 0.4 1.5e-120 402.0 0.4 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KFX88989.1 - 4e-15 55.9 4.8 2.9e-08 33.4 0.1 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase zf-UBP PF02148.19 KFX88992.1 - 2.9e-23 81.9 15.5 3e-19 69.1 2.9 3.4 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KFX88992.1 - 4.5e-23 80.8 4.1 5.1e-23 80.6 0.2 2.7 3 0 0 3 3 3 1 Variant UBP zinc finger UCH PF00443.29 KFX88992.1 - 1.8e-19 70.2 0.0 3.1e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFX88992.1 - 1.4e-10 40.8 0.2 3.3e-10 39.7 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.6 KFX88992.1 - 9.7e-08 32.0 1.2 2e-07 31.0 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 KFX88993.1 - 2.1e-52 177.4 0.0 5e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase NifU_N PF01592.16 KFX88993.1 - 2.3e-51 173.2 0.0 4.6e-51 172.3 0.0 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain Helicase_C PF00271.31 KFX88993.1 - 9.3e-33 112.9 0.0 4e-30 104.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX88993.1 - 2.7e-08 34.0 0.2 7.1e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFX88993.1 - 0.00077 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KFX88993.1 - 0.0098 15.1 0.0 0.0098 15.1 0.0 1.7 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KFX88993.1 - 0.049 12.4 0.0 0.65 8.7 0.0 2.5 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SOG2 PF10428.9 KFX88993.1 - 0.068 12.4 2.9 0.12 11.5 2.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein CMS1 PF14617.6 KFX88993.1 - 0.079 12.3 0.0 0.079 12.3 0.0 2.7 2 1 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KFX88993.1 - 0.18 12.1 0.7 2.5 8.4 0.7 2.6 1 1 0 1 1 1 0 AAA domain GREB1 PF15782.5 KFX88993.1 - 0.59 7.2 3.5 0.8 6.7 3.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Draxin PF15550.6 KFX88993.1 - 1.4 8.7 9.0 2.4 7.9 9.0 1.3 1 0 0 1 1 1 0 Draxin RR_TM4-6 PF06459.12 KFX88993.1 - 3.1 7.5 13.0 5 6.9 13.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.6 KFX88993.1 - 8.2 5.1 6.7 12 4.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rft-1 PF04506.13 KFX88994.1 - 3.3e-146 488.0 19.6 3.7e-146 487.9 19.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KFX88994.1 - 0.032 13.4 18.1 0.0056 15.9 11.8 2.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein FixQ PF05545.11 KFX88994.1 - 0.86 9.6 4.7 17 5.4 0.3 3.6 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF5401 PF17380.2 KFX88995.1 - 0.00068 17.9 27.8 0.00094 17.4 27.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5401) OST3_OST6 PF04756.13 KFX88996.1 - 1.4e-108 362.8 0.0 1.6e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KFX88996.1 - 0.047 14.5 1.3 0.085 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif MerC PF03203.14 KFX88996.1 - 0.48 10.9 4.4 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein VKOR PF07884.14 KFX88996.1 - 1.4 9.1 6.2 0.37 11.0 0.4 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family FtsJ PF01728.19 KFX88997.1 - 1.3e-58 198.0 0.0 1.6e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KFX88997.1 - 0.00021 21.2 0.0 0.00039 20.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX88997.1 - 0.0024 17.7 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX88997.1 - 0.16 12.7 0.0 0.56 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ceramidase_alk PF04734.13 KFX88998.1 - 3.2e-213 709.0 0.0 3.7e-213 708.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFX88998.1 - 1.4e-60 204.0 0.0 2.4e-60 203.2 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal EMP24_GP25L PF01105.24 KFX89007.1 - 1.8e-40 138.8 0.1 2.4e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pyr_redox_2 PF07992.14 KFX89009.1 - 6.1e-43 147.1 0.4 7.2e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX89009.1 - 7.6e-11 42.4 4.4 8.6e-09 35.8 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX89009.1 - 5.2e-07 29.6 6.9 0.19 11.3 0.1 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX89009.1 - 0.0041 17.1 1.9 5.3 7.0 0.1 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX89009.1 - 0.0079 16.4 0.7 4.9 7.4 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX89009.1 - 0.068 12.2 2.4 0.23 10.5 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KFX89009.1 - 0.12 11.6 0.1 4.4 6.5 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX89009.1 - 0.23 10.5 3.5 4.7 6.2 0.2 3.5 4 0 0 4 4 4 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KFX89009.1 - 0.29 10.2 0.2 0.56 9.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_6 PF12697.7 KFX89009.1 - 0.38 11.3 3.9 1.2 9.7 0.3 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family Trp_halogenase PF04820.14 KFX89009.1 - 0.72 8.6 3.7 3.1 6.5 0.1 2.8 3 1 0 3 3 3 0 Tryptophan halogenase Pyridoxal_deC PF00282.19 KFX89010.1 - 8.8e-74 248.5 0.0 1.7e-73 247.5 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFX89010.1 - 0.00078 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF680 PF05079.12 KFX89015.1 - 2 9.1 6.5 0.46 11.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF680) ThrE PF06738.12 KFX89016.1 - 1.2e-75 254.0 12.6 6.6e-71 238.5 1.5 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFX89016.1 - 1.7e-12 47.6 5.7 1.7e-12 47.6 5.7 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Aldedh PF00171.22 KFX89017.1 - 1.4e-159 531.5 0.3 1.7e-159 531.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 KFX89017.1 - 0.0074 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family GMC_oxred_N PF00732.19 KFX89018.1 - 8.8e-50 169.7 0.0 1.2e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX89018.1 - 2.4e-37 128.7 0.0 3.8e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFX89018.1 - 0.00016 21.9 0.1 0.0012 19.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX89018.1 - 0.00016 20.9 0.1 0.00028 20.0 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX89018.1 - 0.00032 19.9 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX89018.1 - 0.002 17.8 0.2 0.01 15.4 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX89018.1 - 0.0025 18.3 0.1 0.94 10.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX89018.1 - 0.0029 16.9 0.0 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX89018.1 - 0.03 13.6 0.0 0.55 9.4 0.0 2.7 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KFX89018.1 - 0.047 13.0 0.1 2.1 7.6 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX89018.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Lactonase PF10282.9 KFX89019.1 - 1.7e-23 83.5 0.1 3.2e-08 33.2 0.0 4.2 1 1 2 4 4 4 4 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KFX89019.1 - 0.0014 18.2 0.1 0.69 9.4 0.0 3.2 2 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Proteasome_A_N PF10584.9 KFX89019.1 - 0.066 12.9 0.6 12 5.6 0.0 3.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Rop-like PF05082.13 KFX89020.1 - 0.00021 21.0 1.5 0.00029 20.6 0.4 1.8 2 0 0 2 2 2 1 Rop-like Uso1_p115_C PF04871.13 KFX89020.1 - 0.0021 18.4 0.5 0.0021 18.4 0.5 1.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Taxilin PF09728.9 KFX89020.1 - 0.0091 15.2 0.4 0.011 15.0 0.4 1.0 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF948 PF06103.11 KFX89020.1 - 0.011 16.0 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 KFX89020.1 - 0.018 15.5 1.1 0.024 15.1 1.1 1.3 1 0 0 1 1 1 0 PhoU domain YabA PF06156.13 KFX89020.1 - 0.022 15.4 0.2 0.028 15.1 0.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ATP-synt_D PF01813.17 KFX89020.1 - 0.024 14.5 0.6 0.028 14.2 0.6 1.2 1 0 0 1 1 1 0 ATP synthase subunit D Ax_dynein_light PF10211.9 KFX89020.1 - 0.027 14.4 0.7 0.027 14.4 0.7 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain LPD11 PF18824.1 KFX89020.1 - 0.044 13.9 0.4 0.28 11.3 0.0 2.3 2 1 0 3 3 3 0 Large polyvalent protein-associated domain 11 KxDL PF10241.9 KFX89020.1 - 0.048 13.9 0.3 0.089 13.1 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein ZapB PF06005.12 KFX89020.1 - 0.057 13.9 0.3 0.069 13.6 0.3 1.4 1 1 0 1 1 1 0 Cell division protein ZapB LPP PF04728.13 KFX89020.1 - 0.057 13.8 0.8 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Sec8_exocyst PF04048.14 KFX89020.1 - 0.071 13.0 0.2 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain SlyX PF04102.12 KFX89020.1 - 0.084 13.5 0.4 0.19 12.4 0.3 1.6 1 1 0 1 1 1 0 SlyX XhlA PF10779.9 KFX89020.1 - 0.12 12.6 1.4 0.22 11.8 1.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA HC2 PF07382.11 KFX89022.1 - 5.9e-05 23.2 23.3 9.4e-05 22.6 23.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 HTH_18 PF12833.7 KFX89022.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain eIF3_subunit PF08597.10 KFX89022.1 - 0.5 10.2 30.7 1.1 9.1 19.5 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Fez1 PF06818.15 KFX89022.1 - 1.3 9.4 13.9 2.7 8.4 13.9 1.4 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.6 KFX89022.1 - 6 5.4 13.8 8.5 4.9 13.8 1.2 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.17 KFX89036.1 - 8.6e-59 198.4 0.0 1.5e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KFX89036.1 - 5.4e-05 23.0 0.0 9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KFX89036.1 - 0.028 14.2 0.1 0.49 10.1 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FUSC_2 PF13515.6 KFX89037.1 - 9.8e-13 48.3 26.2 6e-10 39.3 8.2 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFX89037.1 - 7.9e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KFX89037.1 - 2e-05 23.9 18.8 3.8e-05 22.9 0.9 3.9 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal DUF1097 PF06496.11 KFX89037.1 - 0.0029 17.7 25.4 0.076 13.1 7.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1097) FUSC PF04632.12 KFX89037.1 - 0.0072 14.9 17.5 0.011 14.3 9.5 3.0 2 1 0 2 2 2 2 Fusaric acid resistance protein family 7TM-7TMR_HD PF07698.11 KFX89037.1 - 4.2 7.1 11.8 0.074 12.8 3.2 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Col_cuticle_N PF01484.17 KFX89037.1 - 4.6 7.4 5.1 1.1 9.3 0.3 2.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain ALMT PF11744.8 KFX89037.1 - 9.9 4.9 18.2 0.0049 15.8 4.0 2.5 3 1 0 3 3 3 0 Aluminium activated malate transporter adh_short PF00106.25 KFX89038.1 - 7.2e-44 149.6 0.3 8.1e-44 149.4 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89038.1 - 8.8e-40 136.7 0.1 1.1e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89038.1 - 2.9e-15 56.6 0.8 4.2e-15 56.1 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX89038.1 - 4.8e-05 22.9 0.6 0.00092 18.7 0.6 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFX89038.1 - 0.00028 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFX89038.1 - 0.0033 16.7 0.1 0.0065 15.8 0.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KFX89038.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KFX89038.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFX89038.1 - 0.097 11.9 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_1 PF00561.20 KFX89042.1 - 4.2e-14 52.8 0.1 1.4e-13 51.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX89042.1 - 9e-09 36.2 0.2 1.2e-08 35.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX89042.1 - 0.0018 17.6 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KFX89042.1 - 0.033 12.9 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cupin_2 PF07883.11 KFX89043.1 - 6.7e-09 35.3 1.0 1.4e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KFX89043.1 - 0.0066 16.4 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 KFX89043.1 - 0.049 13.8 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family MannoseP_isomer PF01050.18 KFX89043.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Lyx_isomer PF07385.12 KFX89043.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Bac_rhamnosid6H PF17389.2 KFX89044.1 - 1.5e-06 27.7 0.0 1.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Cyclin_N PF00134.23 KFX89048.1 - 1.9e-43 147.2 0.0 3.3e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX89048.1 - 7.6e-37 126.0 0.0 2.2e-36 124.5 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.27 KFX89049.1 - 5.1e-73 241.1 0.7 1.6e-25 88.8 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFX89049.1 - 4.8e-18 65.4 4.4 6.7e-09 36.1 0.6 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KFX89049.1 - 3.5e-15 54.3 7.4 1e-06 27.8 0.2 5.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFX89049.1 - 7e-15 53.6 5.1 1.8e-06 27.4 0.2 6.2 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 KFX89049.1 - 6.4e-10 38.7 5.5 0.19 11.6 0.0 5.9 5 2 2 7 7 7 3 EF-hand domain pair EF-hand_5 PF13202.6 KFX89049.1 - 4.6e-09 35.4 3.8 3.6e-05 23.1 0.3 4.4 4 0 0 4 4 4 1 EF hand Dockerin_1 PF00404.18 KFX89049.1 - 0.02 15.1 0.2 3.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_9 PF14658.6 KFX89049.1 - 0.05 13.9 0.1 14 6.1 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Metallophos PF00149.28 KFX89058.1 - 1.1e-36 127.2 0.1 2e-36 126.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GH131_N PF18271.1 KFX89059.1 - 6.6e-76 255.4 0.0 8.3e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FAD_binding_3 PF01494.19 KFX89072.1 - 2.1e-78 264.0 0.0 2.7e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFX89072.1 - 4e-47 160.3 0.0 1.1e-46 158.9 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KFX89072.1 - 1.8e-05 24.1 0.2 0.00048 19.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX89072.1 - 0.0014 17.9 0.0 0.0032 16.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX89072.1 - 0.0019 17.7 0.5 0.004 16.6 0.2 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX89072.1 - 0.0036 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KFX89072.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.24 KFX89072.1 - 0.021 14.4 1.8 0.33 10.5 0.2 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX89072.1 - 0.077 13.2 0.2 0.28 11.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KFX89072.1 - 0.085 11.9 0.0 9.7 5.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase CBM_1 PF00734.18 KFX89073.1 - 5.5e-09 35.8 13.7 5.5e-09 35.8 13.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain GMC_oxred_N PF00732.19 KFX89075.1 - 2.5e-09 36.9 0.0 1e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX89075.1 - 2e-08 34.9 0.2 3.1e-06 27.8 0.1 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX89075.1 - 2.9e-05 23.3 0.3 4.6e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX89075.1 - 0.00017 21.1 0.3 0.00026 20.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX89075.1 - 0.004 16.4 0.1 0.0069 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX89075.1 - 0.0073 16.5 0.7 0.024 14.9 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFX89075.1 - 0.03 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFX89075.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KFX89075.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF900 PF05990.12 KFX89075.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 KFX89075.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) Lycopene_cycl PF05834.12 KFX89075.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HET PF06985.11 KFX89081.1 - 2.9e-11 43.9 11.0 3.3e-10 40.5 0.1 3.3 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 KFX89082.1 - 6.1e-106 355.0 25.4 7.1e-106 354.8 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89082.1 - 6.8e-22 77.9 33.1 2.2e-14 53.2 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX89083.1 - 6.2e-12 45.5 0.0 3.1e-11 43.2 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX89083.1 - 6.3e-12 45.2 0.0 7.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFX89083.1 - 2.8e-07 30.6 0.0 8.2e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX89083.1 - 8.3e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX89083.1 - 0.00012 21.1 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX89083.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 KFX89083.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KFX89083.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family FAD_binding_3 PF01494.19 KFX89084.1 - 3.7e-19 69.2 1.9 7.4e-13 48.5 0.2 2.2 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX89084.1 - 1.7e-06 27.5 0.1 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX89084.1 - 9.9e-05 21.8 0.1 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX89084.1 - 0.00021 21.4 0.1 0.00086 19.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX89084.1 - 0.0016 19.0 0.1 0.94 10.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX89084.1 - 0.0016 17.6 2.3 0.0092 15.1 0.4 2.5 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 KFX89084.1 - 0.0046 16.6 0.3 0.068 12.7 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX89084.1 - 0.0076 15.0 0.2 2 7.0 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KFX89084.1 - 0.016 15.2 0.1 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFX89084.1 - 0.092 11.8 0.5 10 5.0 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFX89084.1 - 0.098 11.9 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 KFX89085.1 - 6e-13 49.0 0.0 9.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89085.1 - 3.3e-06 27.7 0.0 1.5e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89085.1 - 0.00044 20.8 0.0 0.0009 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89085.1 - 0.0025 18.5 0.1 0.044 14.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89085.1 - 0.013 15.3 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 KFX89085.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KFX89085.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Herpes_BLLF1 PF05109.13 KFX89085.1 - 5.3 4.9 10.7 8.2 4.3 10.7 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF1682 PF07946.14 KFX89087.1 - 2.6e-106 355.5 0.0 3e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cytochrome_P460 PF16694.5 KFX89089.1 - 0.037 14.4 0.3 0.078 13.3 0.3 1.5 1 0 0 1 1 1 0 Cytochrome P460 Epimerase PF01370.21 KFX89090.1 - 7.1e-07 28.9 0.0 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX89090.1 - 9.9e-05 22.0 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KFX89090.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX89090.1 - 0.0027 17.6 0.0 0.0073 16.2 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 KFX89090.1 - 0.0044 16.2 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.24 KFX89090.1 - 0.063 13.7 0.2 0.12 12.8 0.2 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFX89090.1 - 0.083 11.9 0.0 0.45 9.5 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX89090.1 - 0.2 11.0 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase WD40 PF00400.32 KFX89091.1 - 1.2e-47 158.9 24.6 1.3e-08 35.3 0.1 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 KFX89091.1 - 1.4e-11 44.1 0.2 2.9e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KFX89091.1 - 2.2e-09 36.5 5.5 0.23 10.0 0.1 5.6 3 1 3 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 KFX89091.1 - 2.9e-09 36.6 0.3 1.1e-08 34.8 0.1 2.0 1 1 1 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KFX89091.1 - 6.4e-09 36.0 0.1 0.044 14.1 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KFX89091.1 - 0.0015 18.4 0.3 0.0054 16.6 0.1 2.1 2 0 0 2 2 2 1 F-box Peptidase_M14 PF00246.24 KFX89092.1 - 2e-70 237.9 0.0 2.4e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sulfatase PF00884.23 KFX89096.1 - 5.3e-53 180.4 0.0 6.7e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KFX89096.1 - 8.9e-27 92.7 0.4 1.9e-26 91.6 0.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KFX89096.1 - 1.3e-07 31.5 4.4 4e-07 30.0 0.1 2.6 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFX89096.1 - 0.00013 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Peptidase_M9_N PF08453.10 KFX89096.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal NAD_binding_10 PF13460.6 KFX89097.1 - 7.4e-10 39.0 0.1 1.5e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX89097.1 - 2.2e-06 27.4 0.1 3.7e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KFX89097.1 - 0.0011 18.5 0.3 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX89097.1 - 0.0016 17.9 0.3 0.0053 16.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_7 PF13241.6 KFX89097.1 - 0.0047 17.4 0.2 0.13 12.7 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Epimerase PF01370.21 KFX89097.1 - 0.0076 15.7 0.1 0.017 14.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFX89097.1 - 0.08 12.9 0.6 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX89097.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 KFX89098.1 - 1.5e-12 47.7 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89098.1 - 5.5e-08 33.4 0.0 2.7e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89098.1 - 1.4e-07 31.4 0.0 4e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89098.1 - 9e-07 29.6 0.0 2.6e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89098.1 - 3.1e-05 24.6 0.0 0.00029 21.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFX89098.1 - 0.057 12.3 0.0 0.26 10.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KFX89098.1 - 0.069 12.5 0.0 1.1 8.6 0.0 2.2 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family SH2_2 PF14633.6 KFX89098.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Fringe PF02434.16 KFX89102.1 - 0.0002 20.9 0.1 0.0038 16.7 0.4 2.7 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KFX89102.1 - 0.0079 16.1 1.2 0.018 15.0 1.2 1.5 1 0 0 1 1 1 1 PAN domain GST_C PF00043.25 KFX89103.1 - 6.9e-07 29.4 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX89103.1 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX89103.1 - 0.00018 21.5 0.1 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LAGLIDADG_2 PF03161.13 KFX89103.1 - 0.059 13.4 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family GST_N_3 PF13417.6 KFX89104.1 - 1.1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX89104.1 - 1e-08 35.4 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX89104.1 - 8.6e-08 32.4 0.1 3e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX89104.1 - 0.021 15.0 0.0 0.056 13.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX89104.1 - 0.034 14.2 0.1 0.081 13.0 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2451 PF10474.9 KFX89104.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) DUF913 PF06025.12 KFX89105.1 - 2.5e-135 451.2 0.0 2.5e-135 451.2 0.0 5.3 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KFX89105.1 - 7.9e-120 400.5 6.3 7.9e-120 400.5 6.3 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KFX89105.1 - 2e-94 316.5 0.0 3.3e-94 315.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KFX89105.1 - 5.3e-26 89.2 19.2 6.9e-10 38.0 3.1 4.1 3 0 0 3 3 3 3 Ubiquitin binding region DDHD PF02862.17 KFX89105.1 - 0.49 10.5 2.9 8 6.6 0.4 2.8 2 0 0 2 2 2 0 DDHD domain RabGAP-TBC PF00566.18 KFX89106.1 - 3.7e-48 164.0 0.2 7.7e-47 159.7 0.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KFX89106.1 - 0.0073 16.4 3.5 0.0073 16.4 3.5 3.0 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 Filament PF00038.21 KFX89106.1 - 0.066 12.8 18.9 0.038 13.6 9.1 2.3 1 1 1 2 2 2 0 Intermediate filament protein YabA PF06156.13 KFX89106.1 - 0.96 10.1 14.0 12 6.6 6.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 KFX89106.1 - 1.8 8.6 18.1 2.8 8.0 8.5 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 KFX89106.1 - 3.9 7.8 12.5 0.36 11.1 0.7 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KFX89106.1 - 9.5 6.7 9.9 91 3.6 1.6 3.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) CBS PF00571.28 KFX89107.1 - 0.033 14.6 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 CBS domain DUF1674 PF07896.12 KFX89111.1 - 3.7e-19 68.9 3.6 3.7e-19 68.9 3.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Pribosyltran_N PF13793.6 KFX89112.1 - 2.1e-43 146.9 0.3 8.3e-43 145.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFX89112.1 - 2.1e-42 145.3 2.0 6.8e-34 117.5 1.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFX89112.1 - 3.8e-17 62.2 1.4 7.8e-17 61.2 0.7 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFX89112.1 - 0.0031 17.0 0.2 0.0053 16.2 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.19 KFX89113.1 - 5.1e-58 194.5 0.7 9.8e-58 193.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 KFX89113.1 - 1.4 8.0 5.8 1.8 7.6 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ctf8 PF09696.10 KFX89114.1 - 1.7e-44 151.6 0.0 2.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Ctf8 PPTA PF01239.22 KFX89115.1 - 8.4e-32 108.0 13.5 1.6e-06 27.6 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ANAPC4_WD40 PF12894.7 KFX89116.1 - 4.3e-10 39.8 0.2 0.00069 19.9 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX89116.1 - 0.001 19.8 6.7 0.0034 18.2 0.1 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat OPT PF03169.15 KFX89119.1 - 1.8e-188 628.1 28.7 2.2e-188 627.8 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_7 PF00840.20 KFX89124.1 - 5.3e-198 658.1 15.2 6.2e-198 657.9 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_21 PF03370.13 KFX89126.1 - 1.4e-33 115.5 2.8 2.5e-33 114.6 2.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFX89126.1 - 1.3e-09 38.4 3.9 3e-09 37.3 3.9 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Acyltransferase PF01553.21 KFX89127.1 - 4.5e-32 110.5 0.0 7.8e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SNO PF01174.19 KFX89129.1 - 9.9e-56 188.6 0.0 5.6e-46 156.8 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFX89129.1 - 4.7e-10 39.4 0.0 4.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KFX89129.1 - 0.00039 20.2 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KFX89129.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KFX89129.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 PX PF00787.24 KFX89130.1 - 1.9e-18 66.5 0.0 5.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFX89130.1 - 5.2e-13 49.1 3.9 2.8e-07 30.4 0.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KFX89130.1 - 0.033 13.7 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Acyltransferase PF01553.21 KFX89131.1 - 9.6e-13 47.9 0.0 1.3e-11 44.3 0.0 2.5 2 1 0 2 2 2 1 Acyltransferase Zwint PF15556.6 KFX89135.1 - 0.0044 16.6 3.3 0.0052 16.3 3.3 1.1 1 0 0 1 1 1 1 ZW10 interactor SOG2 PF10428.9 KFX89135.1 - 0.0057 15.9 0.1 0.0061 15.8 0.1 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Taxilin PF09728.9 KFX89135.1 - 0.012 14.8 2.4 0.018 14.2 2.4 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Filament PF00038.21 KFX89135.1 - 0.028 14.0 4.2 0.038 13.6 4.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein SPATA24 PF15175.6 KFX89135.1 - 0.047 13.6 2.4 0.074 13.0 1.5 1.7 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 MIT PF04212.18 KFX89135.1 - 0.07 13.2 0.6 0.07 13.2 0.6 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3584 PF12128.8 KFX89135.1 - 0.3 8.5 13.9 1.2 6.6 14.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2201_N PF13203.6 KFX89135.1 - 0.68 9.5 7.2 0.9 9.1 7.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DHR10 PF18595.1 KFX89135.1 - 1.1 9.3 9.9 0.56 10.3 6.1 2.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CHD5 PF04420.14 KFX89135.1 - 1.2 9.0 3.0 2.4 8.0 2.2 1.8 1 1 1 2 2 2 0 CHD5-like protein T3SSipB PF16535.5 KFX89135.1 - 2.2 8.7 11.1 8.3 6.9 11.2 1.8 1 1 0 1 1 1 0 Type III cell invasion protein SipB DivIC PF04977.15 KFX89136.1 - 0.0014 18.3 9.6 0.021 14.6 4.2 2.4 2 0 0 2 2 2 2 Septum formation initiator ZapB PF06005.12 KFX89136.1 - 0.0035 17.8 3.0 0.74 10.3 0.7 2.5 2 0 0 2 2 2 2 Cell division protein ZapB Imm3 PF14425.6 KFX89136.1 - 0.014 15.4 2.0 0.48 10.5 0.3 2.4 2 0 0 2 2 2 0 Immunity protein Imm3 Halogen_Hydrol PF10112.9 KFX89136.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PikAIV_N PF18605.1 KFX89136.1 - 0.21 11.2 1.5 0.48 10.1 1.5 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain LINES_C PF14695.6 KFX89136.1 - 0.32 10.5 1.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Lines C-terminus PRKG1_interact PF15898.5 KFX89136.1 - 0.34 11.8 6.0 5.4 8.0 0.6 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RPA_interact_M PF14767.6 KFX89136.1 - 0.75 10.4 4.3 2.5 8.8 4.3 1.9 1 0 0 1 1 1 0 Replication protein A interacting middle bZIP_1 PF00170.21 KFX89136.1 - 0.81 9.8 7.5 11 6.2 2.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 KFX89136.1 - 1.5 9.1 8.0 4.7 7.4 1.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_2 PF07716.15 KFX89136.1 - 1.7 8.8 8.2 11 6.1 0.4 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 KFX89136.1 - 2.3 7.5 8.1 0.75 9.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KFX89136.1 - 6.4 6.6 7.8 13 5.6 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ACC_central PF08326.12 KFX89137.1 - 2.2e-286 951.9 0.0 2.7e-286 951.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KFX89137.1 - 1.6e-187 624.1 0.0 2.1e-187 623.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFX89137.1 - 8.1e-52 175.8 0.0 1.5e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFX89137.1 - 4.3e-28 98.1 0.1 8.6e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFX89137.1 - 1.1e-21 76.9 0.0 3.1e-19 69.1 0.0 3.7 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFX89137.1 - 4.5e-18 64.9 0.1 1.4e-17 63.2 0.1 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KFX89137.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 KFX89137.1 - 0.0092 15.5 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KFX89137.1 - 0.0098 16.0 0.0 0.034 14.2 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain Beta_protein PF14350.6 KFX89137.1 - 0.048 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta protein Biotin_lipoyl_2 PF13533.6 KFX89137.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KFX89137.1 - 0.091 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KFX89137.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain NUDE_C PF04880.13 KFX89138.1 - 6.7e-44 150.5 9.8 6.7e-44 150.5 9.8 3.9 2 1 2 4 4 2 1 NUDE protein, C-terminal conserved region Tropomyosin_1 PF12718.7 KFX89138.1 - 0.012 15.7 27.0 4.2 7.5 18.4 4.0 2 1 1 3 3 3 0 Tropomyosin like Dimer_Tnp_Tn5 PF02281.16 KFX89138.1 - 0.067 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Fez1 PF06818.15 KFX89138.1 - 0.24 11.8 22.2 0.39 11.1 10.1 3.0 2 1 1 3 3 3 0 Fez1 ZapB PF06005.12 KFX89138.1 - 0.31 11.5 31.1 0.11 13.0 3.9 4.9 2 1 1 3 3 2 0 Cell division protein ZapB AAA_13 PF13166.6 KFX89138.1 - 0.36 9.4 15.6 0.6 8.7 15.6 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 KFX89138.1 - 0.36 10.9 31.5 0.39 10.8 11.7 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KFX89138.1 - 0.64 11.0 22.8 0.29 12.1 7.4 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 KFX89138.1 - 0.76 9.3 23.6 0.58 9.7 21.4 1.8 2 0 0 2 2 2 0 Intermediate filament protein CCDC144C PF14915.6 KFX89138.1 - 2.9 6.9 23.1 34 3.4 21.7 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF745 PF05335.13 KFX89138.1 - 3 7.5 15.9 0.64 9.7 12.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 KFX89138.1 - 3.1 6.5 11.2 1.9 7.2 9.1 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Chibby PF14645.6 KFX89138.1 - 3.3 8.1 9.3 3.8 8.0 4.1 2.5 1 1 1 2 2 2 0 Chibby family DUF16 PF01519.16 KFX89138.1 - 4.3 7.9 16.4 0.32 11.5 5.5 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 Prominin PF05478.11 KFX89138.1 - 6 4.7 5.5 11 3.9 5.5 1.4 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 KFX89138.1 - 7.5 3.9 21.1 12 3.3 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 KFX89138.1 - 8.5 6.4 22.8 0.58 10.1 5.2 4.8 2 1 1 4 4 4 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KFX89138.1 - 8.7 6.9 12.7 17 5.9 0.2 3.3 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 KFX89138.1 - 9 6.8 19.8 3.5 8.1 4.5 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) FPP PF05911.11 KFX89138.1 - 9.8 4.2 23.0 10 4.1 15.6 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFX89138.1 - 10 6.3 31.6 6.8 6.9 12.5 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MBA1 PF07961.11 KFX89139.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein MARVEL PF01284.23 KFX89139.1 - 4 7.5 19.9 8.2 6.4 17.9 2.4 2 1 1 3 3 3 0 Membrane-associating domain RabGAP-TBC PF00566.18 KFX89140.1 - 3.2e-28 98.9 0.0 5.4e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_28 PF03033.20 KFX89140.1 - 1.2e-16 61.0 0.1 4e-16 59.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain SBE2 PF17076.5 KFX89140.1 - 7e-10 37.8 0.9 1.3e-09 37.0 0.9 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation UDPGT PF00201.18 KFX89140.1 - 9.6e-07 27.9 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX89140.1 - 0.036 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TLD PF07534.16 KFX89143.1 - 3.5e-22 79.1 0.0 4.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 TLD Goodbye PF17109.5 KFX89144.1 - 9.2e-23 81.0 0.0 1.2e-21 77.4 0.0 2.7 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_2 PF07719.17 KFX89144.1 - 2.8e-05 23.9 1.6 0.024 14.7 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 KFX89144.1 - 7.9e-05 22.9 0.0 0.00036 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX89144.1 - 0.0017 18.3 0.0 0.0049 16.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.6 KFX89144.1 - 0.02 14.6 1.8 0.079 12.7 1.2 2.3 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.6 KFX89144.1 - 0.042 14.1 2.1 1.7 9.1 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX89144.1 - 0.071 13.8 0.2 0.071 13.8 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFX89144.1 - 0.079 13.3 0.1 0.73 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 KFX89144.1 - 0.097 13.0 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 KFX89144.1 - 0.1 12.5 0.7 9 6.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX89144.1 - 0.16 12.3 0.5 20 5.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX89144.1 - 1.3 9.6 6.0 0.61 10.6 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF3435 PF11917.8 KFX89146.1 - 2.5e-05 23.4 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Fib_alpha PF08702.10 KFX89146.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family KRAP_IP3R_bind PF14722.6 KFX89146.1 - 0.16 11.7 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Glyco_hydro_43 PF04616.14 KFX89152.1 - 1.3e-12 47.6 0.1 1.8e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX89152.1 - 0.015 15.0 0.2 0.02 14.6 0.2 1.2 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain Mur_ligase_M PF08245.12 KFX89154.1 - 2.1e-06 27.9 0.0 5.5e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Porphobil_deam PF01379.20 KFX89156.1 - 9.1e-13 48.2 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Pectinesterase PF01095.19 KFX89159.1 - 3.9e-37 127.6 7.8 5.4e-37 127.1 7.8 1.1 1 0 0 1 1 1 1 Pectinesterase Ribosomal_L28e PF01778.17 KFX89159.1 - 0.026 15.3 1.2 0.05 14.4 1.2 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family DUF2430 PF10353.9 KFX89159.1 - 0.075 13.4 0.0 6.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) MFS_1 PF07690.16 KFX89160.1 - 1.3e-37 129.6 48.3 3.3e-37 128.2 41.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89160.1 - 5.6e-08 32.1 7.7 5.6e-08 32.1 7.7 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter dTDP_sugar_isom PF00908.17 KFX89160.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase DUF5379 PF17350.2 KFX89160.1 - 0.81 10.0 5.8 0.56 10.5 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5379) Yippee-Mis18 PF03226.14 KFX89163.1 - 4.6e-17 62.1 0.8 5.2e-17 62.0 0.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFX89163.1 - 0.062 13.5 1.1 0.094 12.9 1.1 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I RNA_POL_M_15KD PF02150.16 KFX89163.1 - 0.12 12.3 1.1 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DiS_P_DiS PF06750.13 KFX89163.1 - 0.4 10.8 1.7 20 5.4 0.1 2.2 1 1 2 3 3 3 0 Bacterial Peptidase A24 N-terminal domain ADH_N PF08240.12 KFX89164.1 - 1.7e-29 101.9 0.4 2.8e-29 101.2 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX89164.1 - 3.7e-21 75.5 0.0 6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX89164.1 - 3.7e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFX89164.1 - 8.2e-05 22.0 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFX89164.1 - 0.0003 21.9 0.0 0.00053 21.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFX89164.1 - 0.0036 17.2 0.1 0.0081 16.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 KFX89164.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sen15 PF09631.10 KFX89165.1 - 7.9e-25 87.1 0.0 1.4e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 KFX89166.1 - 1.7e-40 137.0 1.2 3.7e-40 136.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) KAR9 PF08580.10 KFX89166.1 - 5.1 5.5 8.3 1 7.8 4.8 1.4 1 1 0 1 1 1 0 Yeast cortical protein KAR9 EamA PF00892.20 KFX89167.1 - 1.5e-06 28.4 21.4 0.0029 17.8 4.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KFX89167.1 - 1.6e-06 27.5 3.3 2.7e-06 26.8 3.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter Internalin_N PF12354.8 KFX89167.1 - 0.17 12.0 0.3 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Imp-YgjV PF10688.9 KFX89167.1 - 2 8.2 14.1 1.6 8.5 1.4 2.6 2 0 0 2 2 2 0 Bacterial inner membrane protein CLU PF13236.6 KFX89170.1 - 8.9e-77 257.8 0.0 1.4e-76 257.2 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KFX89170.1 - 9.3e-52 175.6 0.0 2.4e-51 174.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 KFX89170.1 - 3.2e-25 88.3 0.4 3.2e-25 88.3 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 KFX89170.1 - 2.3e-23 82.3 11.5 6.5e-10 39.2 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFX89170.1 - 3.6e-20 71.2 7.8 3.6e-07 29.9 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat DUF727 PF05303.12 KFX89170.1 - 0.0021 18.1 0.0 0.0065 16.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 KFX89170.1 - 0.0048 17.0 11.9 0.022 15.0 0.2 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX89170.1 - 0.0061 16.6 7.3 0.18 12.0 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TAA-Trp-ring PF15401.6 KFX89170.1 - 0.12 12.9 2.0 0.65 10.5 2.0 2.3 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin TPR_1 PF00515.28 KFX89170.1 - 0.22 11.4 4.4 5.8 6.9 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 KFX89172.1 - 1e-23 83.8 13.3 2.4e-22 79.4 10.1 2.7 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX89172.1 - 1.6e-19 70.6 0.0 5.7e-11 42.8 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX89172.1 - 2.1e-11 43.9 0.0 9.8e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain Baculo_11_kDa PF06143.11 KFX89172.1 - 0.0053 16.3 0.1 0.015 14.8 0.1 1.8 1 0 0 1 1 1 1 Baculovirus 11 kDa family Glyco_hydro_18 PF00704.28 KFX89179.1 - 2.6e-88 296.7 5.8 3.1e-88 296.5 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFX89180.1 - 2e-25 90.2 0.5 1e-24 87.9 0.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 AltA1 PF16541.5 KFX89181.1 - 9.9e-07 29.6 4.7 0.4 11.6 0.3 3.5 3 0 0 3 3 3 3 Alternaria alternata allergen 1 Cornichon PF03311.14 KFX89182.1 - 0.01 16.1 0.4 0.013 15.8 0.4 1.1 1 0 0 1 1 1 0 Cornichon protein A_deaminase PF00962.22 KFX89184.1 - 2.3e-79 267.1 0.0 2.6e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFX89184.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX89184.1 - 0.043 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family MFS_1 PF07690.16 KFX89186.1 - 1.7e-45 155.5 43.2 1e-44 152.9 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89186.1 - 7.5e-06 25.1 13.5 7.5e-06 25.1 13.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFX89186.1 - 0.09 11.1 4.6 0.032 12.5 1.8 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Dioxygenase_C PF00775.21 KFX89187.1 - 6.3e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase 2OG-FeII_Oxy PF03171.20 KFX89189.1 - 6.4e-20 71.5 0.0 4.8e-19 68.7 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFX89189.1 - 9.3e-10 39.3 0.0 1.4e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CMAS PF02353.20 KFX89190.1 - 2.4e-63 214.0 0.2 3e-63 213.7 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFX89190.1 - 2e-10 41.2 0.0 4.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX89190.1 - 1.3e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89190.1 - 1.7e-08 35.1 0.0 4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89190.1 - 0.00021 21.9 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFX89190.1 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFX89190.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFX89190.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFX89190.1 - 0.053 13.3 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFX89190.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Tctex-1 PF03645.13 KFX89192.1 - 7.6e-33 112.8 0.0 9.8e-33 112.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family RITA PF17066.5 KFX89192.1 - 0.0049 16.5 1.6 0.015 14.9 1.6 1.8 1 1 0 1 1 1 1 RBPJ-interacting and tubulin associated protein Hydrolase_6 PF13344.6 KFX89198.1 - 2e-18 66.4 0.0 3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GCV_T PF01571.21 KFX89199.1 - 3.6e-51 174.0 0.0 4.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 KFX89199.1 - 0.058 13.6 0.0 3.4 7.8 0.0 2.3 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family V-ATPase_H_C PF11698.8 KFX89200.1 - 2.8e-37 127.4 0.0 5.4e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 KFX89200.1 - 5e-23 81.9 0.0 7.5e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H adh_short_C2 PF13561.6 KFX89204.1 - 9.6e-12 44.9 0.2 1.2e-11 44.6 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX89204.1 - 1.6e-11 44.0 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KFX89204.1 - 0.013 15.0 0.1 0.066 12.8 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 KFX89204.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 KFX89204.1 - 0.023 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KFX89204.1 - 0.026 14.4 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX89204.1 - 0.05 13.7 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KFX89204.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SPT16 PF08644.11 KFX89205.1 - 0.0028 17.9 0.0 0.0033 17.6 0.0 1.1 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) CCDC24 PF15669.5 KFX89205.1 - 0.034 14.0 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF2951 PF11166.8 KFX89205.1 - 0.034 14.3 0.7 0.06 13.6 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) phiKZ_IP PF12699.7 KFX89205.1 - 0.04 13.1 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Vma12 PF11712.8 KFX89205.1 - 0.059 13.4 0.1 0.084 12.9 0.1 1.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Spc24 PF08286.11 KFX89205.1 - 0.063 13.5 0.6 0.084 13.1 0.2 1.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Smim3 PF17307.2 KFX89205.1 - 0.14 11.7 0.3 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Small integral membrane protein 3 TRIQK PF15168.6 KFX89205.1 - 0.15 12.0 0.4 1.1 9.2 0.4 2.1 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family Peptidase_S9_N PF02897.15 KFX89206.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain TPR_2 PF07719.17 KFX89207.1 - 7.5e-25 85.0 14.0 6.2e-05 22.8 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFX89207.1 - 1.7e-21 75.1 15.4 0.00052 19.7 0.4 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat STI1 PF17830.1 KFX89207.1 - 4.3e-17 61.8 2.1 8e-17 60.9 2.1 1.5 1 0 0 1 1 1 1 STI1 domain TPR_11 PF13414.6 KFX89207.1 - 8.3e-13 47.8 14.3 0.0006 19.4 0.1 5.3 3 1 2 5 5 5 5 TPR repeat TPR_8 PF13181.6 KFX89207.1 - 1.9e-12 46.3 12.1 0.014 15.6 0.2 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX89207.1 - 7.1e-10 39.0 7.4 0.015 15.6 0.1 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFX89207.1 - 1.2e-09 38.6 1.8 0.0037 17.9 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX89207.1 - 1.6e-08 34.6 3.0 4.6 8.3 0.1 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX89207.1 - 7.1e-08 32.1 6.7 0.0037 17.1 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX89207.1 - 1.3e-07 32.0 2.1 0.15 12.6 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX89207.1 - 7.7e-06 25.6 2.6 0.73 10.0 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX89207.1 - 3.6e-05 23.9 2.8 0.13 12.7 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX89207.1 - 8.7e-05 22.6 0.1 0.0012 19.0 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFX89207.1 - 0.012 16.0 0.0 0.012 16.0 0.0 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 KFX89207.1 - 0.036 14.0 10.7 0.077 13.0 10.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SHNi-TPR PF10516.9 KFX89207.1 - 0.087 12.3 0.9 5.7 6.5 0.1 2.9 3 0 0 3 3 3 0 SHNi-TPR Thump_like PF18096.1 KFX89207.1 - 0.11 12.5 0.1 0.6 10.1 0.1 1.9 2 0 0 2 2 2 0 THUMP domain-like DUF3391 PF11871.8 KFX89207.1 - 0.21 12.1 2.6 0.52 10.8 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) TPR_6 PF13174.6 KFX89207.1 - 0.53 11.0 3.8 93 4.0 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat NARP1 PF12569.8 KFX89207.1 - 9.9 4.9 10.8 0.88 8.4 0.3 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 adh_short PF00106.25 KFX89209.1 - 2.3e-06 27.2 1.2 2.4e-06 27.2 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX89209.1 - 0.047 13.6 0.2 0.053 13.4 0.2 1.0 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.7 KFX89217.1 - 2.5e-14 53.6 0.2 3.4e-13 50.0 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX89217.1 - 7.6e-14 51.9 0.8 3.4e-08 33.9 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX89217.1 - 1.1e-12 47.8 2.4 7.5e-08 32.5 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89217.1 - 2.7e-12 45.7 0.2 5.1e-07 29.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFX89217.1 - 7.8e-10 38.8 1.9 1.6e-05 25.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Crystall PF00030.19 KFX89218.1 - 0.0052 16.9 0.0 0.0067 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin ParA PF10609.9 KFX89220.1 - 5.1e-91 304.5 0.1 6.5e-91 304.1 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFX89220.1 - 1.4e-10 41.3 0.0 6.3e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KFX89220.1 - 9.5e-07 28.4 0.0 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KFX89220.1 - 2.9e-05 24.0 0.8 0.001 19.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KFX89220.1 - 7.9e-05 22.0 1.0 0.00012 21.4 0.4 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 KFX89220.1 - 0.0015 17.5 0.3 0.0025 16.8 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFX89220.1 - 0.0044 16.6 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KFX89220.1 - 0.0053 16.3 0.1 0.013 14.9 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KFX89220.1 - 0.047 13.6 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 RsgA GTPase APS_kinase PF01583.20 KFX89220.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 KFX89220.1 - 0.1 12.4 1.5 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX89220.1 - 0.13 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KFX89220.1 - 0.22 11.9 0.3 0.49 10.8 0.3 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribonucleas_3_3 PF14622.6 KFX89221.1 - 6.9e-23 81.2 0.0 1.3e-22 80.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFX89221.1 - 0.036 14.7 0.0 0.26 11.9 0.0 2.4 1 1 0 1 1 1 0 Ribonuclease III domain HAT_KAT11 PF08214.11 KFX89222.1 - 3.8e-99 332.3 0.0 4.7e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_hydro_16 PF00722.21 KFX89223.1 - 1.5e-43 148.3 0.5 2e-43 147.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AAA PF00004.29 KFX89225.1 - 6.4e-38 130.2 0.0 5.4e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX89225.1 - 4.3e-08 32.8 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Bromodomain PF00439.25 KFX89225.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Bromodomain AAA_2 PF07724.14 KFX89225.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HLH PF00010.26 KFX89226.1 - 9.3e-12 44.7 0.1 4.1e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.22 KFX89234.1 - 1.7e-08 34.1 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KFX89234.1 - 1.3e-07 32.3 0.0 2.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.21 KFX89235.1 - 1.1e-101 340.5 0.0 1.5e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FRB_dom PF08771.11 KFX89235.1 - 0.15 12.4 0.0 0.78 10.2 0.0 2.0 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain PBP PF01161.20 KFX89238.1 - 2.3e-12 47.4 0.1 3e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Beta-lactamase PF00144.24 KFX89239.1 - 8.7e-65 219.1 0.0 9.8e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 KFX89240.1 - 5.7e-08 31.6 0.0 6.5e-06 24.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX89240.1 - 7.1e-08 32.1 1.0 0.00072 18.9 1.4 3.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX89240.1 - 9.5e-07 28.3 0.0 5.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX89240.1 - 3e-06 27.4 0.2 2.5e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFX89240.1 - 0.00021 21.4 0.4 0.0022 18.1 0.0 2.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFX89240.1 - 0.015 14.6 0.3 1.1 8.5 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KFX89240.1 - 0.015 15.3 0.1 0.58 10.1 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KFX89240.1 - 0.018 14.6 0.2 1.7 8.2 0.1 2.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX89240.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3425 PF11905.8 KFX89241.1 - 3.7e-15 56.0 1.5 4.9e-15 55.6 0.5 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) Metal_resist PF13801.6 KFX89241.1 - 0.0076 16.4 0.2 0.016 15.4 0.2 1.6 1 0 0 1 1 1 1 Heavy-metal resistance Tektin PF03148.14 KFX89241.1 - 0.013 14.3 0.6 0.021 13.6 0.6 1.2 1 0 0 1 1 1 0 Tektin family Melibiase_2 PF16499.5 KFX89242.1 - 9.9e-56 189.0 6.6 3.3e-55 187.3 6.6 1.8 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFX89242.1 - 8.6e-09 35.4 0.0 1.5e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX89242.1 - 2.1e-06 26.9 0.0 4.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Melibiase Glyco_hydro_62 PF03664.13 KFX89243.1 - 1.6e-155 516.3 15.7 1.9e-155 516.1 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_43 PF04616.14 KFX89244.1 - 1.3e-52 178.9 5.3 1.3e-52 178.9 5.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KFX89244.1 - 1.1e-37 129.1 4.2 2.5e-37 128.0 4.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KFX89244.1 - 4.7e-09 36.4 0.8 1e-08 35.3 0.8 1.5 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KFX89244.1 - 0.00011 21.9 1.8 0.00017 21.3 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_10 PF00331.20 KFX89245.1 - 4.1e-100 335.0 0.0 4.8e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KFX89245.1 - 0.015 14.6 0.1 0.074 12.4 0.0 1.8 1 1 1 2 2 2 0 Beta-galactosidase Beta-prism_lec PF16458.5 KFX89245.1 - 0.05 13.6 0.2 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 Beta-prism lectin ATP-synt_DE_N PF02823.16 KFX89245.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_hydro_43 PF04616.14 KFX89246.1 - 8.5e-34 117.2 4.0 1.2e-33 116.7 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX89246.1 - 3.8e-24 85.5 0.0 6.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SlpA PF03217.14 KFX89246.1 - 0.038 14.6 0.2 0.47 11.1 0.1 2.6 2 0 0 2 2 2 0 Surface later protein A domain WD40 PF00400.32 KFX89247.1 - 9.5e-05 23.1 11.7 0.5 11.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.25 KFX89260.1 - 0.0079 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PPTA PF01239.22 KFX89265.1 - 1.2e-38 129.7 13.0 1.9e-07 30.6 0.2 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.26 KFX89266.1 - 4e-15 55.8 0.1 1.1e-14 54.4 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFX89266.1 - 9.6e-09 35.5 0.0 2.4e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KFX89266.1 - 0.0019 17.7 0.0 0.0055 16.2 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PRODH PF18327.1 KFX89267.1 - 0.25 11.6 1.1 4.3 7.6 0.2 2.7 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain Peptidase_M48_N PF16491.5 KFX89268.1 - 1.4e-66 223.9 11.1 1.4e-66 223.9 11.1 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KFX89268.1 - 9.2e-45 152.8 0.0 1.8e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KFX89268.1 - 0.00052 19.3 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 KFX89268.1 - 0.2 11.4 0.6 0.51 10.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Lipase_3 PF01764.25 KFX89269.1 - 1.2e-36 125.7 0.0 2.5e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KFX89269.1 - 8.2e-07 29.0 0.4 2e-06 27.7 0.4 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.8 KFX89269.1 - 5.4e-05 22.9 0.7 0.00024 20.8 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFX89269.1 - 8.4e-05 23.3 0.4 0.00015 22.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX89269.1 - 0.00087 18.6 0.1 0.0025 17.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KFX89269.1 - 0.0012 18.6 0.6 0.0012 18.6 0.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase PGAP1 PF07819.13 KFX89269.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFX89269.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.22 KFX89269.1 - 0.021 14.8 0.3 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 Cutinase Abhydrolase_5 PF12695.7 KFX89269.1 - 0.039 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFX89269.1 - 0.16 12.1 0.2 0.26 11.3 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain MitMem_reg PF13012.6 KFX89270.1 - 1.2e-36 125.5 0.2 2.7e-36 124.4 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cyclin PF08613.11 KFX89270.1 - 2.3e-30 106.1 0.1 7.3e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin JAB PF01398.21 KFX89270.1 - 3.5e-30 104.4 0.0 8.4e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cyclin_N PF00134.23 KFX89270.1 - 0.00072 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA_bind_2 PF13725.6 KFX89270.1 - 0.02 14.6 6.9 0.034 13.9 6.9 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain CDC45 PF02724.14 KFX89270.1 - 0.46 8.7 5.4 0.82 7.9 5.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 KFX89270.1 - 0.82 9.4 1.8 1.7 8.3 1.8 1.5 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 KFX89270.1 - 0.87 8.3 1.9 1.4 7.7 1.9 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ADK PF00406.22 KFX89271.1 - 1.3e-58 197.4 0.1 1.7e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFX89271.1 - 7.4e-21 75.0 0.2 1.3e-20 74.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KFX89271.1 - 8.4e-18 64.1 0.0 2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFX89271.1 - 1e-05 26.1 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX89271.1 - 0.0089 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DASH_Spc19 PF08287.11 KFX89271.1 - 0.096 12.6 0.9 14 5.5 0.1 2.4 1 1 0 2 2 2 0 Spc19 Mg_chelatase PF01078.21 KFX89271.1 - 0.1 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Coprogen_oxidas PF01218.18 KFX89272.1 - 3.8e-146 485.4 0.2 4.6e-146 485.2 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 KFX89273.1 - 5.7e-51 171.0 0.2 6.7e-51 170.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFX89273.1 - 4.4e-06 27.0 0.0 5.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NCE101 PF11654.8 KFX89274.1 - 1.3e-09 37.6 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 Mito_carr PF00153.27 KFX89275.1 - 8.5e-30 102.5 1.7 5.4e-14 51.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.13 KFX89276.1 - 4.2e-49 167.6 0.2 5.2e-46 157.5 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KFX89276.1 - 7.7e-18 64.4 2.2 3.7e-15 55.8 0.3 3.6 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KFX89276.1 - 2.5e-10 40.1 0.5 1.8e-05 24.6 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit DUF977 PF06163.11 KFX89276.1 - 0.1 12.6 3.1 1 9.3 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Rio2_N PF09202.11 KFX89276.1 - 0.15 12.3 0.6 75 3.6 0.1 3.4 3 0 0 3 3 3 0 Rio2, N-terminal Peptidase_M16 PF00675.20 KFX89277.1 - 3.2e-16 59.7 0.1 6.1e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFX89277.1 - 9.7e-13 48.5 0.0 1.8e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain JAB PF01398.21 KFX89281.1 - 8.2e-15 54.8 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KFX89281.1 - 5.5e-09 36.2 0.0 9.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KFX89281.1 - 1.8e-05 24.5 0.2 5.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Vma12 PF11712.8 KFX89283.1 - 4.8e-45 153.0 1.2 5.2e-45 152.9 0.1 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KFX89283.1 - 0.0049 17.2 1.1 0.0088 16.4 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MHYT PF03707.16 KFX89283.1 - 6.2 7.1 6.2 2.2 8.5 2.7 1.9 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat polyprenyl_synt PF00348.17 KFX89284.1 - 1.1e-74 250.7 0.0 2e-74 249.9 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFX89284.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pilus_CpaD PF09476.10 KFX89284.1 - 0.056 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DNA_topoisoIV PF00521.20 KFX89287.1 - 2e-123 412.5 0.0 6.9e-123 410.7 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFX89287.1 - 1.5e-48 164.3 3.0 5.5e-48 162.5 3.0 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFX89287.1 - 2.4e-25 89.0 4.1 6.2e-25 87.7 4.1 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFX89287.1 - 8.2e-14 52.1 0.2 2.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFX89287.1 - 5.2e-06 26.6 0.0 2.2e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Toprim domain DUF4354 PF14263.6 KFX89287.1 - 0.032 14.0 1.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4354) Glyco_hydro_65C PF03633.15 KFX89287.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain DUF4441 PF14536.6 KFX89287.1 - 0.082 13.1 0.8 0.43 10.8 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) GATA PF00320.27 KFX89288.1 - 3.9e-05 23.2 15.4 0.02 14.5 0.3 4.0 3 0 0 3 3 3 3 GATA zinc finger Cupin_4 PF08007.12 KFX89288.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Ist1 PF03398.14 KFX89289.1 - 3.6e-61 205.9 3.8 4.6e-61 205.5 3.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ArAE_2_N PF10337.9 KFX89290.1 - 1.2e-27 97.1 3.6 3.8e-16 59.2 0.0 3.1 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KFX89290.1 - 3.9e-09 36.7 19.3 3.9e-09 36.7 19.3 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KFX89290.1 - 9.1e-06 24.8 9.9 9.1e-06 24.8 9.9 4.2 4 0 0 4 4 4 3 Aluminium activated malate transporter ArAE_2 PF10334.9 KFX89290.1 - 0.00043 20.2 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 EURL PF06937.11 KFX89290.1 - 6.7 6.0 8.8 0.37 10.2 1.9 2.1 2 0 0 2 2 2 0 EURL protein GFA PF04828.14 KFX89292.1 - 4.9e-13 49.2 10.5 3e-10 40.3 0.7 3.3 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.16 KFX89292.1 - 0.022 14.8 2.3 0.24 11.5 0.3 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain NOB1_Zn_bind PF08772.11 KFX89292.1 - 0.029 14.5 2.0 7.5 6.8 0.1 2.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Clat_adaptor_s PF01217.20 KFX89293.1 - 2.9e-56 189.4 1.2 3.4e-56 189.1 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.7 KFX89294.1 - 4.2e-53 177.3 0.0 7.6e-35 118.8 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KFX89294.1 - 1.3e-27 97.6 1.5 9e-22 78.6 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KFX89294.1 - 2.9e-13 49.4 0.4 3.7e-05 23.5 0.1 3.9 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFX89294.1 - 3.1e-12 46.6 0.1 0.00042 20.6 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KFX89294.1 - 2.3e-10 40.7 0.0 0.00036 20.8 0.0 3.8 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 KFX89294.1 - 4.7e-05 23.3 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 KFX89294.1 - 0.017 15.0 0.6 4.7 7.3 0.1 3.5 4 0 0 4 4 4 0 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KFX89294.1 - 0.069 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 KFX89294.1 - 0.23 10.1 0.1 0.41 9.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 KFX89294.1 - 0.3 10.6 0.2 0.51 9.8 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Septin PF00735.18 KFX89295.1 - 2e-119 398.0 0.0 2e-119 398.0 0.0 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFX89295.1 - 4.1e-08 33.3 0.7 1.1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX89295.1 - 6.2e-05 22.6 1.7 0.0029 17.2 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFX89295.1 - 7e-05 23.4 1.0 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KFX89295.1 - 0.0014 19.0 0.1 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 KFX89295.1 - 0.0018 17.6 1.3 0.0058 16.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KFX89295.1 - 0.0036 17.5 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFX89295.1 - 0.0039 17.1 1.2 0.0039 17.1 1.2 3.4 3 1 0 3 3 2 1 RsgA GTPase Ras PF00071.22 KFX89295.1 - 0.0091 15.6 1.1 0.039 13.6 0.0 2.5 3 1 0 3 3 3 1 Ras family AAA_29 PF13555.6 KFX89295.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFX89295.1 - 0.026 14.8 2.4 0.033 14.4 0.1 2.4 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFX89295.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFX89295.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX89295.1 - 0.074 13.4 0.4 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KFX89295.1 - 0.076 12.8 2.7 3.5 7.3 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KFX89295.1 - 0.091 12.3 5.4 0.14 11.7 5.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_7 PF12775.7 KFX89295.1 - 0.099 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KFX89295.1 - 0.14 12.2 8.6 0.89 9.6 0.0 3.5 3 1 0 3 3 2 0 Dynamin family DUF3987 PF13148.6 KFX89295.1 - 1.7 7.6 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 KFX89295.1 - 2.4 8.2 7.0 4.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Atg14 PF10186.9 KFX89295.1 - 4.7 6.2 9.5 7 5.6 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFX89295.1 - 5.3 7.1 14.2 9.1 6.3 14.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Strep_SA_rep PF06696.11 KFX89295.1 - 6.5 6.9 7.0 2.5 8.2 3.6 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat MFS_1 PF07690.16 KFX89297.1 - 2e-33 115.8 33.2 2e-33 115.8 33.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KFX89297.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.5 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Lipase_GDSL PF00657.22 KFX89298.1 - 7.4e-11 42.4 0.0 9.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFX89298.1 - 0.00036 21.0 2.4 0.0011 19.3 2.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family YbaB_DNA_bd PF02575.16 KFX89299.1 - 0.21 11.9 4.6 0.18 12.0 0.8 2.9 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Peptidase_C13 PF01650.18 KFX89300.1 - 6.4e-41 140.6 0.0 8.1e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ELF PF03317.13 KFX89300.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 ELF protein His_Phos_1 PF00300.22 KFX89301.1 - 0.00015 21.5 2.4 0.87 9.2 0.0 4.0 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) FMO-like PF00743.19 KFX89302.1 - 1.3e-14 53.5 0.0 6.7e-14 51.2 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX89302.1 - 3.4e-14 52.8 0.1 1.4e-10 40.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX89302.1 - 1.8e-13 50.4 0.0 4e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX89302.1 - 1.1e-11 44.5 0.1 2.7e-09 36.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX89302.1 - 2.4e-07 30.9 0.3 3.6e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX89302.1 - 5.4e-06 26.9 2.2 0.0095 16.5 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX89302.1 - 5.4e-05 23.2 3.6 0.0089 16.0 0.2 3.8 3 1 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFX89302.1 - 8.9e-05 21.9 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFX89302.1 - 0.00034 20.3 6.9 0.00054 19.7 1.4 3.1 2 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX89302.1 - 0.0066 15.2 0.4 0.55 8.9 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.18 KFX89302.1 - 0.013 15.4 0.3 0.024 14.5 0.3 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX89302.1 - 0.02 15.0 0.1 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFX89302.1 - 0.23 10.8 0.0 4.8 6.5 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KFX89302.1 - 0.25 10.4 0.5 1.2 8.2 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX89302.1 - 0.36 9.9 4.2 0.076 12.1 0.4 1.8 3 0 0 3 3 3 0 FAD binding domain Glyco_hydro_7 PF00840.20 KFX89304.1 - 4.4e-195 648.5 12.8 5e-195 648.3 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FeoB_associated PF12669.7 KFX89305.1 - 0.0069 16.8 1.3 0.021 15.2 1.3 1.8 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 KFX89305.1 - 1 9.2 4.1 0.26 11.1 0.7 1.7 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) LSM PF01423.22 KFX89306.1 - 5.1e-16 58.1 0.0 1.8e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 LSM domain PPR_3 PF13812.6 KFX89306.1 - 2.8e-15 56.1 0.0 0.0048 16.9 0.0 6.5 4 2 1 6 6 6 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 KFX89306.1 - 1.2e-14 54.2 0.6 0.29 11.3 0.0 8.0 7 2 2 9 9 9 3 PPR repeat family PPR_long PF17177.4 KFX89306.1 - 1.9e-07 30.6 0.1 0.058 12.7 0.0 4.1 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFX89306.1 - 3.5e-07 30.0 13.5 5.7 7.4 0.2 7.2 8 0 0 8 8 8 4 PPR repeat TPR_14 PF13428.6 KFX89306.1 - 0.011 16.5 8.4 38 5.5 0.2 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat SM-ATX PF14438.6 KFX89306.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain PPR_1 PF12854.7 KFX89306.1 - 0.056 13.2 0.0 85 3.0 0.0 4.9 6 0 0 6 6 6 0 PPR repeat TPR_7 PF13176.6 KFX89306.1 - 0.14 12.2 0.2 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX89307.1 - 5.4e-08 32.3 0.5 0.27 11.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX89307.1 - 3.9e-07 29.7 0.2 0.34 11.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Glyco_transf_17 PF04724.13 KFX89307.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 TPR_8 PF13181.6 KFX89307.1 - 0.039 14.2 2.5 26 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX89307.1 - 0.16 11.7 0.2 0.91 9.3 0.0 2.4 3 0 0 3 3 3 0 TPR repeat Surp PF01805.20 KFX89311.1 - 4e-11 42.7 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Surp module YL1 PF05764.13 KFX89311.1 - 2.6 8.1 0.0 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 YL1 nuclear protein VASt PF16016.5 KFX89314.1 - 2.6e-34 118.9 0.2 3.9e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain AAA_11 PF13086.6 KFX89317.1 - 7.9e-60 202.8 0.1 1.4e-59 202.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFX89317.1 - 9.6e-56 188.6 0.0 1.5e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX89317.1 - 5.6e-12 45.8 0.0 1.6e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX89317.1 - 2.4e-09 37.7 0.0 2.3e-08 34.5 0.0 2.6 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.9 KFX89317.1 - 1.1e-05 24.9 0.3 0.0001 21.7 0.2 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFX89317.1 - 4e-05 23.7 0.0 0.00022 21.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFX89317.1 - 5.1e-05 23.1 0.0 0.29 10.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KFX89317.1 - 0.00012 21.7 0.5 0.0018 17.9 0.0 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFX89317.1 - 0.00074 19.8 0.2 0.0062 16.8 0.2 2.5 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 KFX89317.1 - 0.0016 18.3 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 KFX89317.1 - 0.0032 17.4 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 KFX89317.1 - 0.0046 17.4 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFX89317.1 - 0.0096 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 KFX89317.1 - 0.0099 15.5 0.1 0.032 13.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 KFX89317.1 - 0.013 14.9 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 KFX89317.1 - 0.022 15.2 1.3 0.085 13.3 0.0 2.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.6 KFX89317.1 - 0.025 13.9 0.0 8.9 5.6 0.0 3.0 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 KFX89317.1 - 0.026 14.5 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 KFX89317.1 - 0.027 14.2 0.5 0.51 10.0 0.5 2.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX89317.1 - 0.032 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KFX89317.1 - 0.039 13.3 0.5 0.92 8.8 0.0 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.19 KFX89317.1 - 0.086 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 KFX89317.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KFX89317.1 - 0.11 11.6 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase SKI PF01202.22 KFX89317.1 - 0.11 12.6 0.2 0.4 10.8 0.1 1.9 1 1 1 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 KFX89317.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KFX89317.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 KFX89317.1 - 0.15 11.9 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain E1-E2_ATPase PF00122.20 KFX89320.1 - 3e-35 121.4 22.8 7e-29 100.6 0.8 3.5 3 1 0 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 KFX89320.1 - 2.4e-19 70.5 0.1 9.6e-19 68.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX89320.1 - 8.1e-18 63.9 0.0 2.3e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 KFX89320.1 - 2.2e-15 56.8 0.0 2.2e-15 56.8 0.0 2.5 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFX89320.1 - 8.9e-13 48.1 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFX89320.1 - 2.1e-05 24.4 2.9 5.5e-05 23.0 1.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FliMN_C PF01052.20 KFX89320.1 - 0.085 12.9 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term HAD PF12710.7 KFX89320.1 - 0.12 12.8 0.0 0.42 11.0 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFX89320.1 - 0.57 10.0 5.2 0.067 13.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) bZIP_1 PF00170.21 KFX89324.1 - 0.00035 20.6 10.6 0.0004 20.4 5.2 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX89324.1 - 0.022 14.8 8.9 0.11 12.6 2.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SART-1 PF03343.13 KFX89324.1 - 0.23 9.9 8.6 0.31 9.5 8.6 1.1 1 0 0 1 1 1 0 SART-1 family DNA_ligase_A_M PF01068.21 KFX89329.1 - 4.9e-60 202.7 0.2 3.2e-47 160.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFX89329.1 - 5e-43 147.4 0.0 9.4e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFX89329.1 - 2.4e-28 98.6 0.0 1.1e-27 96.5 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFX89329.1 - 1.7e-05 25.2 0.1 2.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 RNA ligase PNKP_ligase PF16542.5 KFX89329.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain tRNA-synt_2 PF00152.20 KFX89330.1 - 1.5e-85 287.1 0.0 2.1e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFX89330.1 - 8.3e-09 35.3 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KFX89330.1 - 0.055 13.7 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IQ PF00612.27 KFX89332.1 - 0.0012 18.5 2.8 0.0031 17.2 2.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PFU PF09070.11 KFX89332.1 - 0.061 13.6 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) PH PF00169.29 KFX89337.1 - 7e-24 84.4 0.6 1e-12 48.4 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KFX89337.1 - 3e-09 37.2 1.1 0.0016 18.8 0.2 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KFX89337.1 - 3.3e-08 33.9 0.3 0.0032 17.8 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KFX89337.1 - 1.4e-05 25.2 0.1 2.8e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFX89337.1 - 0.00016 21.7 0.2 0.00045 20.3 0.1 1.7 2 0 0 2 2 2 1 PH domain DNA_pol_B PF00136.21 KFX89340.1 - 1.1e-113 380.3 1.6 1.4e-113 380.0 0.9 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KFX89340.1 - 5.4e-56 189.3 1.3 9.9e-56 188.4 1.3 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KFX89340.1 - 1.9e-41 142.3 0.0 3.8e-41 141.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain UAA PF08449.11 KFX89340.1 - 2.2e-24 86.2 0.4 3.3e-24 85.6 0.4 1.2 1 0 0 1 1 1 1 UAA transporter family DNA_pol_alpha_N PF12254.8 KFX89340.1 - 5.1e-24 84.1 9.7 5.1e-24 84.1 9.7 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Nuc_sug_transp PF04142.15 KFX89340.1 - 0.0023 17.2 0.1 0.0035 16.6 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter DNA_pol_B_2 PF03175.13 KFX89340.1 - 0.014 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral CDC45 PF02724.14 KFX89340.1 - 8.4 4.5 7.9 15 3.7 7.9 1.3 1 0 0 1 1 1 0 CDC45-like protein PPR_2 PF13041.6 KFX89341.1 - 1e-25 89.7 0.1 4.9e-17 61.9 0.0 4.1 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KFX89341.1 - 4.5e-11 42.7 0.1 1e-05 25.5 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KFX89341.1 - 5.8e-08 32.5 4.3 0.00057 20.0 0.1 5.3 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 KFX89341.1 - 1.9e-07 30.7 0.2 7e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFX89341.1 - 0.0031 17.2 8.7 0.021 14.5 0.0 4.9 7 0 0 7 7 7 1 PPR repeat YodL PF14191.6 KFX89341.1 - 0.17 12.7 0.4 4.6 8.2 0.0 3.0 3 0 0 3 3 3 0 YodL-like RRM_1 PF00076.22 KFX89343.1 - 0.0022 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LON_substr_bdg PF02190.16 KFX89344.1 - 1.3e-18 67.6 0.0 1.5e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain DUF4210 PF13915.6 KFX89351.1 - 2.6e-33 114.4 0.1 6e-33 113.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KFX89351.1 - 6.8e-23 80.6 0.7 6.8e-23 80.6 0.7 1.8 2 0 0 2 2 2 1 Chromosome segregation during meiosis Mis12 PF05859.12 KFX89354.1 - 1.3e-40 138.5 0.0 2e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.6 KFX89355.1 - 3.8e-29 100.6 0.0 2.9e-08 33.8 0.0 8.7 8 1 1 9 9 9 5 PPR repeat family PPR_3 PF13812.6 KFX89355.1 - 6.3e-18 64.6 0.2 6.6e-07 29.3 0.0 6.5 4 3 2 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 KFX89355.1 - 6.6e-14 51.1 0.4 0.012 15.9 0.1 6.9 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KFX89355.1 - 3.2e-12 45.9 0.2 0.085 12.6 0.1 8.1 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 KFX89355.1 - 6.1e-06 25.8 0.0 0.00014 21.3 0.0 3.1 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KFX89355.1 - 0.035 14.0 0.0 26 4.7 0.0 4.8 5 1 0 5 5 5 0 Mitochondrial ATPase expression RPM2 PF08579.11 KFX89355.1 - 0.036 14.5 0.1 0.35 11.3 0.3 2.6 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Vps39_2 PF10367.9 KFX89355.1 - 0.15 12.6 0.4 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 His_Phos_2 PF00328.22 KFX89356.1 - 8.2e-15 55.0 0.0 1.3e-09 38.0 0.0 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KFX89357.1 - 1e-15 58.0 0.0 1.9e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cupin_2 PF07883.11 KFX89358.1 - 2.7e-06 27.0 0.0 7.3e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KFX89358.1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Methyltransf_25 PF13649.6 KFX89359.1 - 3.9e-15 56.3 0.0 9.9e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89359.1 - 8.4e-15 55.2 0.0 1.9e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89359.1 - 1.8e-10 40.8 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89359.1 - 5.4e-10 39.9 0.0 9.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX89359.1 - 1e-05 25.5 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX89359.1 - 0.00056 19.3 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KFX89359.1 - 0.0028 17.3 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 KFX89359.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFX89359.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PRMT5 PF05185.16 KFX89359.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CHAP PF05257.16 KFX89362.1 - 0.0085 16.6 0.7 0.026 15.1 0.1 2.1 2 1 0 2 2 2 1 CHAP domain AIM3 PF17096.5 KFX89362.1 - 0.038 14.9 0.2 0.038 14.9 0.2 5.5 6 1 0 6 6 6 0 Altered inheritance of mitochondria protein 3 Pkinase PF00069.25 KFX89364.1 - 3.3e-23 82.4 0.0 5.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KFX89364.1 - 2.7e-12 45.8 1.4 0.026 14.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 KFX89364.1 - 1.3e-08 35.3 9.7 5.2e-05 23.9 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_EZ PF13513.6 KFX89364.1 - 1.3e-06 28.8 0.3 0.0089 16.5 0.4 4.3 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KFX89364.1 - 1.3e-05 25.5 0.1 0.6 10.5 0.2 4.0 3 1 0 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KFX89364.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX89364.1 - 0.0031 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RTP1_C1 PF10363.9 KFX89364.1 - 0.0066 16.6 0.1 1.5 9.1 0.1 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 N_formyltrans_C PF18216.1 KFX89364.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain AMP-binding PF00501.28 KFX89365.1 - 8.2e-27 93.9 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme LRR_9 PF14580.6 KFX89367.1 - 1.8e-57 193.6 0.4 3.4e-57 192.7 0.1 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KFX89367.1 - 9.6e-08 31.7 1.0 1.7e-07 30.9 0.2 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KFX89367.1 - 1.1e-06 28.9 2.0 0.00042 20.6 0.2 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 KFX89367.1 - 0.015 14.7 0.9 0.028 13.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KFX89367.1 - 0.056 13.5 1.3 17 5.8 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat DAPG_hydrolase PF18089.1 KFX89367.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain Nup88 PF10168.9 KFX89367.1 - 0.22 9.3 1.6 0.66 7.7 0.7 1.8 1 1 0 2 2 2 0 Nuclear pore component ATP-synt_C PF00137.21 KFX89368.1 - 2.1e-25 88.8 33.7 7.3e-16 58.3 11.4 2.8 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KFX89368.1 - 0.026 13.8 1.8 0.072 12.4 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Oxidored_q2 PF00420.24 KFX89368.1 - 3.8 7.2 9.8 1.4 8.5 2.2 3.3 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TFIIA_gamma_C PF02751.14 KFX89369.1 - 2.3e-24 85.2 2.4 4.1e-24 84.5 2.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KFX89369.1 - 4.9e-24 84.1 0.1 6.6e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Methyltransf_11 PF08241.12 KFX89371.1 - 3.8e-08 33.9 0.0 7.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX89371.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89371.1 - 8.8e-05 23.1 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89371.1 - 0.00045 20.9 0.0 0.00082 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89371.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX89371.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HeLo PF14479.6 KFX89373.1 - 7.3e-09 35.8 3.6 8.5e-07 29.0 3.6 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation THDPS_N PF14790.6 KFX89373.1 - 0.16 11.8 0.2 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal FliG_C PF01706.16 KFX89374.1 - 0.19 11.9 2.3 0.52 10.5 0.3 2.6 2 0 0 2 2 2 0 FliG C-terminal domain Fungal_lectin_2 PF18647.1 KFX89375.1 - 6.3e-27 94.0 0.6 1.6e-26 92.7 0.6 1.7 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KFX89375.1 - 3.6e-12 47.1 0.2 8e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX89375.1 - 2e-06 27.9 0.0 8.2e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.28 KFX89376.1 - 1.1e-64 219.2 0.0 1.3e-64 218.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX89376.1 - 4.4e-10 39.9 7.3 4.4e-10 39.9 7.3 3.1 2 1 0 2 2 2 1 Chitin recognition protein Reprolysin_3 PF13582.6 KFX89377.1 - 0.0021 18.6 0.0 0.0047 17.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 KFX89377.1 - 0.021 14.4 0.5 0.1 12.2 0.2 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.24 KFX89377.1 - 0.042 13.7 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Matrixin Reprolysin_5 PF13688.6 KFX89377.1 - 0.056 13.6 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 LysM PF01476.20 KFX89378.1 - 5.4e-14 52.0 0.7 0.017 15.2 0.0 4.4 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.12 KFX89378.1 - 0.57 10.5 3.3 11 6.3 0.3 2.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) ABC2_membrane PF01061.24 KFX89380.1 - 2.8e-78 262.2 56.6 5.3e-43 146.9 22.8 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFX89380.1 - 3.1e-36 124.9 0.0 6.5e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX89380.1 - 2.3e-31 107.6 16.8 2.4e-29 101.0 0.1 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX89380.1 - 1.5e-14 54.3 0.1 4.1e-14 53.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal SMC_N PF02463.19 KFX89380.1 - 3.6e-05 23.3 0.0 0.13 11.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KFX89380.1 - 4.2e-05 23.2 0.6 0.00084 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX89380.1 - 4.5e-05 23.4 0.3 0.00086 19.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFX89380.1 - 0.00012 22.5 0.1 0.017 15.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 KFX89380.1 - 0.00015 21.0 33.3 0.0021 17.2 8.7 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFX89380.1 - 0.0002 21.3 0.0 1.8 8.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KFX89380.1 - 0.00052 20.2 0.1 0.13 12.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KFX89380.1 - 0.0012 19.2 0.1 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX89380.1 - 0.0018 18.0 1.6 0.016 14.9 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFX89380.1 - 0.002 18.6 0.0 0.66 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX89380.1 - 0.0031 17.3 0.1 0.4 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFX89380.1 - 0.0049 16.5 0.6 0.46 10.0 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KFX89380.1 - 0.019 14.7 0.1 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KFX89380.1 - 0.021 13.9 0.3 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KFX89380.1 - 0.031 14.0 0.1 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KFX89380.1 - 0.051 14.0 0.0 6.5 7.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFX89380.1 - 0.062 13.5 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFX89380.1 - 0.079 13.4 0.1 10 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX89380.1 - 0.092 12.7 3.8 1.8 8.4 0.4 2.7 3 0 0 3 3 2 0 NACHT domain AAA_23 PF13476.6 KFX89380.1 - 0.097 13.2 0.1 0.27 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 KFX89380.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Rad51 Rad17 PF03215.15 KFX89380.1 - 0.15 12.0 0.0 8.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF1129 PF06570.11 KFX89380.1 - 4.1 6.9 6.4 7 6.1 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF5542 PF17696.1 KFX89380.1 - 5.5 7.2 6.3 20 5.4 6.3 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Transferase PF02458.15 KFX89381.1 - 3.1e-14 52.5 0.0 3.4e-13 49.0 0.0 2.3 1 1 0 1 1 1 1 Transferase family Transferase PF02458.15 KFX89382.1 - 3.1e-21 75.5 0.0 1.2e-20 73.7 0.0 1.7 1 1 0 1 1 1 1 Transferase family DUF4407 PF14362.6 KFX89385.1 - 0.27 10.6 1.9 0.31 10.3 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIEZO PF15917.5 KFX89399.1 - 0.0055 16.2 10.2 0.0094 15.5 10.2 1.4 1 0 0 1 1 1 1 Piezo CAF-1_p150 PF11600.8 KFX89399.1 - 0.012 15.4 31.0 0.014 15.1 31.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 KFX89399.1 - 0.062 13.1 14.7 0.073 12.9 14.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 KFX89399.1 - 0.092 12.7 19.6 0.12 12.3 19.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.17 KFX89399.1 - 0.16 12.1 2.1 0.18 11.9 2.1 1.2 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.9 KFX89399.1 - 0.16 10.2 6.5 0.19 10.0 6.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.13 KFX89399.1 - 0.19 10.5 10.1 0.2 10.4 10.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 KFX89399.1 - 0.45 8.8 14.2 0.45 8.7 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 KFX89399.1 - 0.55 9.7 6.9 0.61 9.5 6.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TERB2 PF15101.6 KFX89399.1 - 0.68 10.0 6.4 0.78 9.8 6.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 KFX89399.1 - 0.7 9.9 5.3 0.78 9.8 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 KFX89399.1 - 0.75 9.7 16.2 0.87 9.5 16.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CTU2 PF10288.9 KFX89399.1 - 0.79 10.0 9.9 1.1 9.5 9.9 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Connexin PF00029.19 KFX89399.1 - 1.3 8.8 9.7 1.5 8.5 9.7 1.3 1 0 0 1 1 1 0 Connexin LMBR1 PF04791.16 KFX89399.1 - 1.6 7.5 3.7 1.7 7.4 3.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2828 PF11443.8 KFX89399.1 - 1.8 6.5 12.8 2.4 6.2 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NARP1 PF12569.8 KFX89399.1 - 2.1 7.2 19.7 2.6 6.9 19.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MDM10 PF12519.8 KFX89399.1 - 2.3 7.0 6.8 2.4 6.9 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 eIF-3_zeta PF05091.12 KFX89399.1 - 2.4 7.1 12.5 2.7 6.9 12.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_11 PF13086.6 KFX89399.1 - 2.7 7.7 11.1 3.1 7.5 11.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 KFX89399.1 - 3.8 6.9 11.9 4.3 6.7 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF853 PF05872.12 KFX89399.1 - 4.4 5.8 5.8 5.2 5.5 5.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Presenilin PF01080.17 KFX89399.1 - 6.5 5.4 13.5 7.2 5.3 13.5 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFX89399.1 - 8.2 5.1 6.0 8.3 5.1 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 KFX89399.1 - 8.6 5.5 6.0 9.2 5.4 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EOS1 PF12326.8 KFX89399.1 - 9 6.2 5.4 11 5.9 5.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein Cofilin_ADF PF00241.20 KFX89400.1 - 1.5e-19 70.0 0.0 1.7e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 KFX89401.1 - 9.7e-27 93.4 0.1 1.3e-26 93.0 0.1 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain LETM1 PF07766.13 KFX89404.1 - 3e-15 56.3 1.2 2e-13 50.3 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein RRM_1 PF00076.22 KFX89405.1 - 1.3e-10 41.0 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX89405.1 - 0.00036 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.20 KFX89406.1 - 5.6e-16 58.5 1.1 9.1e-16 57.8 1.1 1.3 1 0 0 1 1 1 1 RF-1 domain Glyco_hydro_35 PF01301.19 KFX89409.1 - 1.3e-89 300.9 0.0 2.1e-89 300.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KFX89409.1 - 3.8e-62 209.3 1.3 9.6e-62 208.0 1.3 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 IF-2B PF01008.17 KFX89409.1 - 3.5e-59 200.3 10.7 5.6e-35 120.9 0.0 3.1 3 1 0 3 3 3 2 Initiation factor 2 subunit family BetaGal_dom4_5 PF13364.6 KFX89409.1 - 1.5e-53 180.2 8.7 1.9e-30 105.8 0.4 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KFX89409.1 - 5.5e-22 77.1 0.1 1.2e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF4646 PF15496.6 KFX89409.1 - 0.0069 17.0 0.0 0.032 14.8 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF4849 PF16141.5 KFX89409.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 ESP PF16590.5 KFX89409.1 - 0.12 12.7 0.3 0.37 11.1 0.3 1.8 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Cytadhesin_P30 PF07271.11 KFX89409.1 - 0.28 10.7 13.8 0.79 9.2 13.8 1.7 1 0 0 1 1 1 0 Cytadhesin P30/P32 Allexi_40kDa PF05549.11 KFX89409.1 - 0.53 9.7 2.0 0.52 9.8 0.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein AcetylCoA_hydro PF02550.15 KFX89410.1 - 2.7e-48 164.6 0.0 4.5e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KFX89410.1 - 1.4e-40 138.8 0.0 2.3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_88 PF07470.13 KFX89410.1 - 4.6e-17 62.1 0.1 9.2e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CorA PF01544.18 KFX89410.1 - 0.00026 20.4 0.2 0.001 18.5 0.3 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Asp PF00026.23 KFX89411.1 - 5.1e-11 42.6 0.4 8.2e-11 41.9 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TMEM154 PF15102.6 KFX89411.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 KFX89411.1 - 0.045 14.1 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 KFX89411.1 - 0.048 12.5 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Amnionless DUF4690 PF15756.5 KFX89411.1 - 0.38 11.4 3.1 0.25 12.0 0.4 2.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Syndecan PF01034.20 KFX89411.1 - 8.5 6.4 5.2 17 5.4 5.2 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 KFX89413.1 - 5.4e-71 239.0 0.0 1e-70 238.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89413.1 - 4.6e-49 167.0 0.0 6.9e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX89413.1 - 0.00025 20.0 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFX89413.1 - 0.025 13.9 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Med15_fungi PF05397.12 KFX89413.1 - 0.061 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 Mur_ligase_M PF08245.12 KFX89414.1 - 9.1e-05 22.5 0.2 0.00018 21.6 0.2 1.5 1 1 0 1 1 1 1 Mur ligase middle domain PRK PF00485.18 KFX89415.1 - 1.8e-06 27.8 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFX89415.1 - 6.7e-05 23.4 0.0 0.00017 22.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX89415.1 - 0.00034 21.0 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KFX89415.1 - 0.00054 19.2 0.0 0.0013 18.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain Thymidylate_kin PF02223.17 KFX89415.1 - 0.00082 19.1 0.0 0.19 11.4 0.0 2.7 2 1 1 3 3 3 1 Thymidylate kinase AAA_17 PF13207.6 KFX89415.1 - 0.00091 19.7 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX89415.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX89415.1 - 0.004 17.3 0.6 0.039 14.1 0.6 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX89415.1 - 0.01 15.1 0.2 0.074 12.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KFX89415.1 - 0.013 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 KFX89415.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX89415.1 - 0.018 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFX89415.1 - 0.019 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFX89415.1 - 0.021 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KFX89415.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 KFX89415.1 - 0.045 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 KFX89415.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFX89415.1 - 0.054 13.2 0.0 0.88 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFX89415.1 - 0.061 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 KFX89415.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFX89415.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX89415.1 - 0.078 13.2 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFX89415.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 KFX89415.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 KFX89415.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KFX89415.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KFX89415.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 KFX89415.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ExsD PF16806.5 KFX89418.1 - 0.039 13.9 8.3 0.067 13.1 8.3 1.4 1 1 0 1 1 1 0 Antiactivator protein ExsD Exonuc_VII_L PF02601.15 KFX89418.1 - 0.066 12.8 5.0 0.077 12.5 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M2 PF01401.18 KFX89418.1 - 3.4 6.2 8.5 4.2 5.9 8.5 1.0 1 0 0 1 1 1 0 Angiotensin-converting enzyme AAA_13 PF13166.6 KFX89418.1 - 8.5 4.9 13.4 3.6 6.1 11.1 1.4 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KFX89419.1 - 3e-10 39.6 0.8 5.4e-10 38.7 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89419.1 - 3.6e-06 27.0 11.7 6.5e-06 26.2 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 KFX89420.1 - 2.6e-47 161.6 0.4 3.3e-47 161.3 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Amidohydro_1 PF01979.20 KFX89422.1 - 8.2e-21 74.7 1.6 3.5e-19 69.3 1.6 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX89422.1 - 4.4e-20 72.6 1.9 6.4e-13 49.0 0.4 2.3 1 1 1 2 2 2 2 Amidohydrolase family FMO-like PF00743.19 KFX89423.1 - 8.3e-15 54.2 0.0 2e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX89423.1 - 3.8e-10 39.5 0.0 5.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX89423.1 - 3.3e-08 33.2 0.1 0.00081 18.7 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX89423.1 - 2.5e-06 27.6 0.0 7.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX89423.1 - 0.00036 20.2 0.0 0.53 9.8 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX89423.1 - 0.0019 18.2 0.0 0.0057 16.7 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX89423.1 - 0.0055 15.5 0.1 0.011 14.4 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KFX89423.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KFX89423.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFX89423.1 - 0.066 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KFX89423.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF1996 PF09362.10 KFX89425.1 - 4.5e-49 167.6 2.2 1.6e-27 97.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) MFS_1 PF07690.16 KFX89426.1 - 3.1e-27 95.4 20.6 4e-27 95.1 20.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFX89427.1 - 1e-45 156.2 41.6 1.3e-35 123.0 17.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89427.1 - 1.6e-12 47.1 28.4 8.1e-12 44.7 11.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Peptidase_C41 PF05417.11 KFX89427.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease Arylsulfotran_2 PF14269.6 KFX89428.1 - 3.2e-75 253.3 2.4 4.2e-75 252.9 2.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFX89428.1 - 1.3e-17 63.8 0.8 2.8e-16 59.4 0.8 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PNTB PF02233.16 KFX89429.1 - 1.1e-173 578.5 23.7 1.1e-173 578.5 23.7 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KFX89429.1 - 1.7e-74 249.8 0.3 4.9e-74 248.2 0.3 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFX89429.1 - 3e-38 131.2 0.0 9.8e-38 129.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KFX89429.1 - 1.3e-30 105.7 2.8 1.3e-30 105.7 2.8 4.3 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 KFX89429.1 - 0.0064 16.2 0.2 0.031 14.0 0.2 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 KFX89429.1 - 0.0064 15.9 0.4 0.52 9.6 0.1 2.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFX89429.1 - 0.025 13.8 0.4 0.065 12.5 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX89429.1 - 0.086 11.9 1.1 0.18 10.9 1.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 KFX89430.1 - 0.00022 20.4 0.1 0.00034 19.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89430.1 - 0.024 14.8 15.5 0.055 13.6 15.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_N PF02837.18 KFX89431.1 - 2.6e-14 53.5 0.0 6.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFX89431.1 - 1.6e-11 43.9 0.0 1.5e-10 40.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KFX89431.1 - 5.6e-11 43.1 0.1 4.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFX89431.1 - 0.017 15.7 0.1 0.078 13.5 0.1 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain DJ-1_PfpI PF01965.24 KFX89432.1 - 4.9e-07 29.7 0.0 8.1e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Mre11_DNA_bind PF04152.14 KFX89433.1 - 1.4e-52 178.4 0.3 2.7e-52 177.5 0.3 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFX89433.1 - 5.9e-15 56.3 1.7 2.9e-14 54.1 1.7 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX89433.1 - 1.3e-05 25.5 0.1 0.00028 21.1 0.1 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pox_Ag35 PF03286.14 KFX89433.1 - 7.3 6.3 12.6 32 4.2 12.6 2.0 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_S19 PF00203.21 KFX89434.1 - 1.4e-27 95.4 0.2 1.7e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 SnoaL_2 PF12680.7 KFX89435.1 - 0.012 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pkinase_C PF00433.24 KFX89435.1 - 0.038 14.7 1.0 17 6.2 0.1 3.1 2 0 0 2 2 2 0 Protein kinase C terminal domain DUF2848 PF11010.8 KFX89439.1 - 0.014 15.0 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) PEP-utilisers_N PF05524.13 KFX89439.1 - 0.71 10.1 5.8 0.98 9.6 0.2 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal Herpes_BTRF1 PF04682.12 KFX89441.1 - 0.68 9.2 2.1 1.4 8.2 2.1 1.5 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region ArfGap PF01412.18 KFX89442.1 - 3e-37 127.3 0.1 1.2e-36 125.4 0.1 2.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AA_permease PF00324.21 KFX89444.1 - 7e-124 414.0 34.9 7.9e-124 413.8 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX89444.1 - 3.9e-31 108.3 39.0 4.5e-31 108.1 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_33 PF13671.6 KFX89445.1 - 4e-22 78.9 0.0 5.2e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX89445.1 - 1.9e-07 31.7 0.0 2.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX89445.1 - 3.3e-06 27.6 0.1 5.9e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX89445.1 - 0.00017 21.0 0.0 0.00021 20.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 KFX89445.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 KFX89445.1 - 0.0076 16.1 0.5 0.12 12.3 0.5 2.1 1 1 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.22 KFX89445.1 - 0.051 12.7 0.0 0.092 11.9 0.0 1.3 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KFX89445.1 - 0.065 12.4 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KFX89445.1 - 0.085 13.1 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KFX89446.1 - 7.7e-30 104.0 27.4 1.4e-15 57.1 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX89446.1 - 2.5e-09 36.5 16.1 4.3e-07 29.1 4.0 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KFX89446.1 - 5.8e-07 28.4 23.6 0.0074 14.9 9.9 2.9 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KFX89446.1 - 0.0024 16.8 6.9 0.0024 16.8 6.9 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter E1-E2_ATPase PF00122.20 KFX89446.1 - 0.11 12.0 3.8 2 7.9 2.8 2.6 2 0 0 2 2 2 0 E1-E2 ATPase WD40 PF00400.32 KFX89447.1 - 1.2e-27 95.5 0.4 3.8e-07 30.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89447.1 - 3.9e-16 59.1 0.1 0.0054 17.0 0.0 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX89447.1 - 9.6e-05 22.3 0.6 0.085 12.7 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFX89447.1 - 0.00026 20.2 0.4 0.31 10.0 0.1 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.8 KFX89447.1 - 0.00048 18.9 0.9 0.00091 18.0 0.2 1.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KFX89447.1 - 0.015 14.9 0.5 0.46 10.0 0.4 2.5 1 1 1 2 2 2 0 PQQ-like domain WD40_like PF17005.5 KFX89447.1 - 0.023 14.0 0.3 0.31 10.3 0.1 2.7 1 1 2 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 KFX89447.1 - 0.035 13.0 0.3 4.7 6.0 0.1 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DNA_ligase_C PF17879.1 KFX89447.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase C-terminal domain Ge1_WD40 PF16529.5 KFX89447.1 - 0.17 10.8 2.3 5.1 6.0 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FTHFS PF01268.19 KFX89448.1 - 2.7e-254 844.5 0.2 3.9e-254 844.0 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFX89448.1 - 5.5e-67 224.0 1.8 5.5e-67 224.0 1.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFX89448.1 - 8.2e-39 132.5 0.5 1.5e-38 131.6 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KFX89448.1 - 0.0059 15.6 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KFX89448.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HORMA PF02301.18 KFX89449.1 - 5.4e-34 117.6 0.1 6.4e-34 117.4 0.1 1.0 1 0 0 1 1 1 1 HORMA domain DUF1068 PF06364.12 KFX89449.1 - 0.013 15.4 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) GTP_EFTU PF00009.27 KFX89450.1 - 1.4e-49 168.3 0.0 3.4e-49 167.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFX89450.1 - 2.6e-43 146.5 5.7 4.1e-43 145.9 5.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFX89450.1 - 3.6e-20 71.8 0.0 6.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX89450.1 - 2.3e-07 31.1 0.1 5.2e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KFX89450.1 - 9.5e-06 25.3 0.0 3.4e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KFX89450.1 - 4.8e-05 23.4 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFX89450.1 - 0.0035 16.8 0.0 0.0085 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 KFX89450.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 KFX89450.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 KFX89450.1 - 0.072 12.9 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KFX89450.1 - 0.14 12.4 1.7 0.31 11.3 1.7 1.5 1 0 0 1 1 1 0 Snurportin1 adh_short PF00106.25 KFX89451.1 - 7e-24 84.4 0.0 8.9e-23 80.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89451.1 - 5.6e-17 62.1 0.1 2.8e-16 59.8 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89451.1 - 0.00019 21.4 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX89451.1 - 0.062 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HMG_box PF00505.19 KFX89453.1 - 2.9e-15 56.4 0.8 6.7e-15 55.3 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX89453.1 - 3.5e-14 53.2 1.0 9.6e-14 51.7 1.0 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KFX89453.1 - 3.1e-10 40.4 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFX89453.1 - 1.6e-07 31.3 0.6 3.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF87 PF01935.17 KFX89453.1 - 0.14 12.2 1.4 0.35 10.9 1.5 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain HMG_box_5 PF14887.6 KFX89453.1 - 0.22 11.5 0.9 0.46 10.5 0.6 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Actino_peptide PF14408.6 KFX89453.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.0 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes Pkinase PF00069.25 KFX89455.1 - 1.2e-60 205.2 0.0 1.3e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89455.1 - 6.8e-32 110.8 0.0 8.8e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX89455.1 - 4.8e-06 25.8 0.1 6e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFX89455.1 - 6.1e-05 22.5 0.1 0.0002 20.8 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX89455.1 - 0.00048 20.1 0.0 0.00087 19.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX89455.1 - 0.00091 18.6 0.0 0.031 13.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KFX89455.1 - 0.0089 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFX89455.1 - 0.019 14.6 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aldo_ket_red PF00248.21 KFX89458.1 - 1e-64 218.6 0.0 1.3e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IDO PF01231.18 KFX89459.1 - 3.9e-166 553.2 0.0 4.5e-166 553.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase p450 PF00067.22 KFX89462.1 - 1.2e-81 274.9 0.0 1.4e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane_5 PF13346.6 KFX89462.1 - 0.0042 16.7 0.2 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ASL_C PF08328.11 KFX89462.1 - 0.2 11.7 0.2 0.5 10.5 0.0 1.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal PMT PF02366.18 KFX89464.1 - 1.4e-84 283.5 16.0 1.9e-84 283.1 16.0 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFX89464.1 - 2.4e-32 112.1 0.5 2.4e-32 112.1 0.5 3.0 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFX89464.1 - 6.7e-18 65.2 0.4 1.1e-17 64.5 0.4 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KFX89464.1 - 0.003 17.8 10.7 0.011 16.0 10.3 2.1 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Zn_clus PF00172.18 KFX89467.1 - 0.0062 16.6 9.6 0.0062 16.6 9.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KFX89467.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 PAS fold CbiJ PF02571.14 KFX89467.1 - 0.063 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Flavokinase PF01687.17 KFX89468.1 - 2.6e-33 114.7 0.0 3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase SelP_N PF04592.14 KFX89469.1 - 0.26 10.7 8.5 0.28 10.5 8.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4336 PF14234.6 KFX89476.1 - 5.8e-16 58.6 0.0 6.7e-10 38.7 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Pil1 PF13805.6 KFX89479.1 - 7.6e-123 409.2 0.1 9.9e-123 408.8 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2385 PF09539.10 KFX89479.1 - 0.12 12.9 0.2 5.5 7.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2385) DUF3568 PF12092.8 KFX89479.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) LSM PF01423.22 KFX89480.1 - 9.3e-08 31.7 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain XPG_N PF00752.17 KFX89481.1 - 1.5e-33 115.3 0.0 5.3e-33 113.5 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFX89481.1 - 5.5e-27 94.0 0.0 1.7e-26 92.4 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KFX89481.1 - 0.0022 17.8 2.2 0.0022 17.8 2.2 3.2 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KFX89481.1 - 0.0029 18.2 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF1943 PF09172.11 KFX89481.1 - 0.0098 15.2 0.1 0.024 13.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DnaJ-X PF14308.6 KFX89483.1 - 4.4e-76 255.0 3.1 4.4e-76 255.0 3.1 2.4 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KFX89483.1 - 9e-25 86.6 0.3 2e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.17 KFX89483.1 - 2.2e-13 50.0 0.0 4.7e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFX89483.1 - 8.4e-13 48.3 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX89483.1 - 5.6e-05 22.4 0.1 0.00066 18.9 0.0 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX89483.1 - 0.0037 16.7 0.0 0.012 15.1 0.0 1.9 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Macro PF01661.21 KFX89483.1 - 0.082 13.0 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Macro domain C2-set_2 PF08205.12 KFX89483.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Cyt-b5 PF00173.28 KFX89485.1 - 3.8e-15 55.8 0.0 5.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TRM PF02005.16 KFX89486.1 - 5.7e-107 358.1 0.0 1.6e-93 313.9 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase NIBRIN_BRCT_II PF16508.5 KFX89486.1 - 1.2e-36 125.6 0.0 3.5e-36 124.1 0.0 1.9 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KFX89486.1 - 5.9e-08 33.0 0.1 1.6e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KFX89486.1 - 3.2e-05 23.7 0.0 9.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Met_10 PF02475.16 KFX89486.1 - 0.12 12.1 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein Inositol_P PF00459.25 KFX89487.1 - 8.5e-66 222.2 0.0 9.8e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Antimicrobial_9 PF08104.11 KFX89487.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Ponericin L family EcsC PF12787.7 KFX89488.1 - 0.51 10.0 4.6 0.96 9.1 4.6 1.5 1 1 0 1 1 1 0 EcsC protein family SMC_Nse1 PF07574.13 KFX89489.1 - 8.1e-71 237.9 0.8 1e-70 237.6 0.8 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFX89489.1 - 7.8e-15 54.9 7.6 1.2e-14 54.3 7.6 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 KFX89489.1 - 0.14 12.5 7.2 0.22 11.9 7.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_9 PF13901.6 KFX89489.1 - 0.17 11.9 4.6 0.19 11.7 2.8 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 KFX89489.1 - 1.1 9.5 5.2 3.4 7.9 5.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain C1_2 PF03107.16 KFX89489.1 - 1.3 9.4 6.1 0.12 12.7 1.4 1.6 2 0 0 2 2 2 0 C1 domain Ysc84 PF04366.12 KFX89490.1 - 3.3e-44 149.7 0.1 5.6e-44 149.0 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator WD40 PF00400.32 KFX89491.1 - 2.3e-18 66.2 15.2 2e-05 25.2 0.0 9.6 9 0 0 9 9 9 4 WD domain, G-beta repeat SPRY PF00622.28 KFX89491.1 - 2.9e-06 27.4 0.0 0.00013 22.0 0.0 2.7 2 0 0 2 2 2 1 SPRY domain PQQ_3 PF13570.6 KFX89491.1 - 0.27 11.8 2.3 3.1 8.4 0.2 3.7 3 0 0 3 3 3 0 PQQ-like domain CHCH PF06747.13 KFX89495.1 - 1.2e-06 28.4 4.0 2.1e-06 27.7 4.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KFX89495.1 - 0.00074 19.9 5.3 0.0008 19.8 3.4 2.0 1 1 0 1 1 1 1 GCK domain DUF4644 PF15486.6 KFX89496.1 - 0.046 13.5 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) DUF2396 PF09654.10 KFX89497.1 - 0.028 14.5 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) NIR_SIR PF01077.22 KFX89497.1 - 0.081 12.4 1.0 0.57 9.7 0.6 1.9 1 1 1 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain Pkinase_fungal PF17667.1 KFX89502.1 - 1.2e-106 356.9 0.0 1.6e-106 356.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFX89502.1 - 0.003 17.0 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KFX89503.1 - 1.7e-07 30.9 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFX89503.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFX89503.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase NmrA PF05368.13 KFX89504.1 - 3.3e-22 79.2 0.0 4.2e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX89504.1 - 3.1e-14 53.3 0.0 6e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KFX89504.1 - 0.089 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 KFX89504.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3328 PF11807.8 KFX89506.1 - 2.3e-52 177.9 0.0 2.8e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) U-box PF04564.15 KFX89514.1 - 1.4e-05 25.2 0.0 1.5e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KFX89514.1 - 0.056 13.3 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Myb_DNA-binding PF00249.31 KFX89517.1 - 5.8e-24 84.0 0.7 1.3e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX89517.1 - 4.5e-16 58.8 0.5 1.5e-11 44.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 KFX89517.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 THEG4 PF15834.5 KFX89517.1 - 0.078 13.0 3.3 0.1 12.6 2.0 1.7 1 1 1 2 2 2 0 Testis highly expressed protein 4 MARVEL PF01284.23 KFX89519.1 - 3.9e-11 43.2 15.8 5.7e-11 42.6 15.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain SARAF PF06682.12 KFX89519.1 - 2.4 7.7 10.4 4.8 6.7 10.4 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SOG2 PF10428.9 KFX89519.1 - 6.3 5.9 6.3 7.7 5.6 6.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4246 PF14033.6 KFX89521.1 - 6.9e-121 404.5 0.0 8.1e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Lipoprotein_9 PF03180.14 KFX89522.1 - 0.027 13.6 0.1 0.12 11.5 0.0 1.8 1 1 1 2 2 2 0 NLPA lipoprotein PAN_3 PF08277.12 KFX89523.1 - 5.4e-08 32.5 11.9 0.053 13.3 0.6 3.7 3 0 0 3 3 3 3 PAN-like domain PAN_4 PF14295.6 KFX89523.1 - 0.00039 20.3 15.1 0.14 12.1 0.2 3.8 3 0 0 3 3 3 3 PAN domain Pectate_lyase_3 PF12708.7 KFX89524.1 - 1.5e-76 257.0 6.6 4.4e-65 219.5 1.4 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX89524.1 - 4.4e-06 26.3 0.3 0.14 11.9 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RFXA_RFXANK_bdg PF15289.6 KFX89525.1 - 0.089 13.1 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain NAD_binding_10 PF13460.6 KFX89528.1 - 0.0014 18.5 0.0 0.0023 17.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX89528.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KFX89528.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 KFX89529.1 - 9.9e-81 271.9 17.3 1.2e-80 271.6 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89529.1 - 6.1e-22 78.0 28.3 9e-22 77.5 25.9 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX89529.1 - 1.9 7.2 14.4 0.11 11.4 4.1 2.3 2 0 0 2 2 2 0 MFS_1 like family zf-C2H2 PF00096.26 KFX89530.1 - 0.022 15.2 3.2 0.022 15.2 3.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 KFX89530.1 - 0.34 11.2 2.8 1 9.7 2.8 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFX89530.1 - 0.49 10.2 14.2 0.059 13.1 2.7 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFX89530.1 - 0.92 10.5 17.3 0.54 11.2 2.6 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 KFX89534.1 - 7.7e-11 41.8 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX89534.1 - 4.4e-07 29.4 0.0 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX89534.1 - 1.6e-05 25.1 0.2 4.5e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX89534.1 - 0.00036 19.4 0.0 0.00049 18.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KFX89534.1 - 0.0004 19.6 0.0 0.00069 18.8 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KFX89534.1 - 0.0012 18.5 0.7 0.0029 17.2 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX89534.1 - 0.0016 18.9 0.0 0.0062 17.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX89534.1 - 0.0047 16.3 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFX89534.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KFX89534.1 - 0.014 14.8 0.2 0.027 13.8 0.2 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX89534.1 - 0.034 13.2 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFX89534.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 KFX89534.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX89534.1 - 0.22 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M24 PF00557.24 KFX89535.1 - 6.6e-47 159.9 0.1 8e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFX89535.1 - 1.2e-20 73.5 8.7 2.4e-20 72.5 8.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFX89535.1 - 4.2e-05 23.5 4.8 0.00011 22.2 4.8 1.8 1 0 0 1 1 1 1 MYND finger ApbA_C PF08546.11 KFX89535.1 - 0.098 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal zf-HIT PF04438.16 KFX89535.1 - 0.38 10.7 3.1 0.9 9.5 3.1 1.7 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.14 KFX89536.1 - 1.3e-50 170.8 12.4 1.5e-50 170.6 12.4 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KFX89537.1 - 2.4e-28 97.8 4.4 2.7e-06 28.0 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89537.1 - 4e-12 46.3 0.4 0.00015 22.0 0.2 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX89537.1 - 0.062 11.9 0.4 2 6.9 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CR6_interact PF10147.9 KFX89538.1 - 0.02 14.6 1.3 0.031 14.0 1.3 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Fungal_trans PF04082.18 KFX89540.1 - 3.7e-08 32.7 0.1 5.7e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RasGAP PF00616.19 KFX89544.1 - 4.1e-30 105.1 0.0 7e-26 91.2 0.0 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KFX89544.1 - 0.0049 17.1 0.0 0.015 15.5 0.0 1.9 1 1 0 1 1 1 1 C2 domain UPF0506 PF11703.8 KFX89548.1 - 0.25 11.7 4.5 1.2 9.6 4.7 2.0 1 1 1 2 2 2 0 UPF0506 Toxin_18 PF08087.11 KFX89548.1 - 1.3 9.1 7.3 8.5 6.5 0.2 2.7 2 0 0 2 2 2 0 Conotoxin O-superfamily Ribosomal_S2 PF00318.20 KFX89553.1 - 1.4e-65 220.6 0.0 5.1e-65 218.7 0.0 2.0 3 0 0 3 3 3 1 Ribosomal protein S2 CBS PF00571.28 KFX89553.1 - 1.1e-32 112.2 8.7 8.1e-09 35.8 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KFX89553.1 - 3.8e-10 39.5 0.0 1.2e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain Importin_rep_4 PF18808.1 KFX89554.1 - 3.1e-31 107.5 0.9 3.1e-31 107.5 0.9 4.3 4 1 1 5 5 3 1 Importin repeat Importin_rep_5 PF18816.1 KFX89554.1 - 1.8e-21 76.2 3.1 3.9e-21 75.1 2.1 2.2 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KFX89554.1 - 6.6e-19 68.0 15.1 1.2e-10 41.7 0.4 8.6 7 1 2 9 9 9 3 HEAT-like repeat Importin_rep_6 PF18829.1 KFX89554.1 - 7.3e-16 58.2 1.3 3.4e-15 56.1 0.6 2.6 2 0 0 2 2 2 1 Importin repeat 6 HEAT PF02985.22 KFX89554.1 - 2.6e-15 55.2 8.4 0.0055 16.8 0.0 10.0 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 KFX89554.1 - 6e-15 55.4 13.6 9.8e-05 22.7 0.0 8.2 5 2 1 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX89554.1 - 2.5e-10 40.8 0.0 0.064 13.9 0.0 5.6 3 1 3 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFX89554.1 - 1.5e-07 31.3 0.3 0.063 12.8 0.0 4.6 2 2 2 4 4 4 2 CLASP N terminal MMS19_C PF12460.8 KFX89554.1 - 1.5e-07 30.9 3.3 5.2e-07 29.1 0.1 3.2 2 2 2 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KFX89554.1 - 3.8e-06 26.9 0.2 7.1 6.5 0.0 5.2 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KFX89554.1 - 0.00047 20.0 0.0 0.021 14.5 0.0 3.8 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.6 KFX89554.1 - 0.00059 19.6 0.3 2.8 7.6 0.3 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) Arm PF00514.23 KFX89554.1 - 0.0012 18.8 4.2 0.19 11.8 0.1 4.5 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat Dopey_N PF04118.14 KFX89554.1 - 0.0021 17.2 0.6 1.7 7.7 0.0 3.3 3 1 0 3 3 3 2 Dopey, N-terminal IBN_N PF03810.19 KFX89554.1 - 0.011 15.6 3.3 0.018 15.0 0.1 3.2 4 0 0 4 4 3 0 Importin-beta N-terminal domain IKBKB_SDD PF18397.1 KFX89554.1 - 0.011 15.0 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Cnd3 PF12719.7 KFX89554.1 - 0.012 14.8 0.0 0.27 10.4 0.0 2.9 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain DNA_alkylation PF08713.11 KFX89554.1 - 0.055 13.2 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 DNA alkylation repair enzyme Phage_Gp23 PF10669.9 KFX89554.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DALR_1 PF05746.15 KFX89554.1 - 1 9.5 7.0 8.9 6.5 0.0 4.4 3 1 1 4 4 4 0 DALR anticodon binding domain YtxH PF12732.7 KFX89554.1 - 9.5 6.8 8.1 3.3 8.3 0.6 3.3 3 0 0 3 3 3 0 YtxH-like protein adh_short PF00106.25 KFX89555.1 - 2.1e-21 76.3 0.0 2.4e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89555.1 - 3.9e-14 52.8 0.0 1e-12 48.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89555.1 - 5.8e-11 42.6 0.0 9.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX89555.1 - 0.00039 20.0 0.0 0.00074 19.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX89555.1 - 0.0004 19.6 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KFX89555.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KFX89555.1 - 0.015 15.7 0.3 0.043 14.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Semialdhyde_dh PF01118.24 KFX89555.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFX89555.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 KFX89556.1 - 1.3e-05 25.2 8.7 2.4e-05 24.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX89556.1 - 2e-05 23.6 0.0 3.7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PTPA PF03095.15 KFX89563.1 - 1.2e-115 386.1 0.0 1.5e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Aminotran_3 PF00202.21 KFX89564.1 - 1.5e-29 102.9 0.0 2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF1980 PF09323.10 KFX89565.1 - 0.052 13.5 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Tmemb_9 PF05434.11 KFX89565.1 - 0.17 11.8 1.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 TMEM9 ubiquitin PF00240.23 KFX89566.1 - 5.8e-22 77.2 0.3 6.9e-22 77.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX89566.1 - 7.9e-10 38.4 0.4 8.7e-10 38.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFX89566.1 - 0.00035 20.7 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KFX89566.1 - 0.025 14.9 0.3 0.028 14.8 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KFX89566.1 - 0.035 14.7 0.0 0.04 14.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 KFX89566.1 - 0.059 13.8 0.1 0.095 13.2 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain Sugar_tr PF00083.24 KFX89567.1 - 1.3e-05 24.2 4.7 1.6e-05 24.0 4.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89567.1 - 1.6e-05 24.0 6.1 2e-05 23.7 6.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX89567.1 - 0.0021 16.7 6.2 0.0025 16.4 6.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF842 PF05811.13 KFX89569.1 - 0.00022 20.9 0.8 0.22 11.2 0.1 4.2 3 2 0 4 4 4 2 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.18 KFX89569.1 - 0.28 11.0 43.1 1.3 8.8 6.8 6.1 3 1 2 5 5 5 0 Apolipoprotein A1/A4/E domain RRF PF01765.19 KFX89569.1 - 0.83 9.6 7.0 0.81 9.6 0.0 3.8 3 1 1 4 4 4 0 Ribosome recycling factor PABP PF00658.18 KFX89570.1 - 1.1e-24 86.4 2.9 2.9e-18 65.8 0.3 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RINGv PF12906.7 KFX89570.1 - 2.7e-16 59.4 8.5 4.5e-16 58.7 8.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFX89570.1 - 0.0023 18.2 8.3 0.0039 17.5 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KFX89570.1 - 0.75 9.9 2.5 1.6 8.8 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFX89570.1 - 4.7 7.1 6.5 8 6.3 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFX89570.1 - 4.8 7.1 5.4 9.4 6.2 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX89570.1 - 7.8 6.2 5.9 16 5.3 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Lactamase_B PF00753.27 KFX89571.1 - 5.8e-17 62.3 0.0 2e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX89571.1 - 0.00052 19.6 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Jiv90 PF14901.6 KFX89571.1 - 0.17 12.0 0.2 0.73 10.0 0.1 2.0 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone BTB_2 PF02214.22 KFX89573.1 - 1.9e-07 31.4 0.0 0.00014 22.1 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain Phage-tail_3 PF13550.6 KFX89574.1 - 0.038 13.8 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative phage tail protein Cu_bind_like PF02298.17 KFX89574.1 - 0.057 13.4 0.1 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KFX89574.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain AF-4 PF05110.13 KFX89574.1 - 2.7 6.0 5.6 3.2 5.7 5.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 KFX89577.1 - 5.6e-41 137.8 19.3 1.6e-06 28.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KFX89577.1 - 1.4e-10 40.9 0.1 3.5e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFX89577.1 - 6.8e-09 35.9 0.3 1.3 9.3 0.0 5.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFX89577.1 - 1.9e-08 34.0 0.4 5.7e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KFX89577.1 - 3.7e-05 22.6 2.8 2.4 6.7 0.0 5.0 3 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KFX89577.1 - 0.00051 20.0 0.1 1.4 9.0 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFX89577.1 - 0.055 12.8 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 KFX89577.1 - 0.087 12.4 1.6 4.8 6.7 0.7 2.8 1 1 1 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KFX89577.1 - 0.095 12.6 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 F-box CDC4_D PF16856.5 KFX89577.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Fungal_trans PF04082.18 KFX89580.1 - 1.9e-28 99.3 0.0 3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89580.1 - 1.3e-09 38.0 10.9 2.1e-09 37.3 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Putative_PNPOx PF01243.20 KFX89582.1 - 8.5e-09 35.5 0.8 1.2e-07 31.9 0.1 2.2 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KFX89582.1 - 0.00052 20.6 0.5 0.0011 19.5 0.5 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyr_redox_2 PF07992.14 KFX89583.1 - 5.4e-44 150.6 0.0 8.1e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 KFX89583.1 - 3.6e-32 111.3 0.0 7.6e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Pyr_redox PF00070.27 KFX89583.1 - 3.9e-13 49.8 0.0 8.5e-10 39.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.11 KFX89583.1 - 3.6e-07 29.9 0.0 6.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 LisH EF-hand_1 PF00036.32 KFX89583.1 - 6e-06 25.4 0.3 1.5e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX89583.1 - 0.00022 20.9 0.3 0.00059 19.6 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KFX89583.1 - 0.0018 17.7 0.3 0.0035 16.8 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFX89583.1 - 0.002 18.6 0.1 0.0061 17.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 KFX89583.1 - 0.065 12.5 0.2 0.81 8.9 0.4 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF5588 PF17826.1 KFX89584.1 - 0.053 12.4 0.1 0.079 11.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Glyco_hydro_28 PF00295.17 KFX89585.1 - 1.7e-97 326.4 19.9 2e-97 326.2 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase PF03211.13 KFX89585.1 - 0.096 12.2 8.8 0.27 10.7 8.8 1.9 1 1 0 1 1 1 0 Pectate lyase MFS_1 PF07690.16 KFX89586.1 - 1.4e-44 152.5 58.5 7.3e-44 150.1 56.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX89586.1 - 7.9e-24 84.0 27.2 1.2e-23 83.5 27.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX89586.1 - 1e-12 47.7 15.2 1e-12 47.7 15.2 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter Transp_inhibit PF18791.1 KFX89586.1 - 0.092 12.3 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Prenyltransf PF01255.19 KFX89587.1 - 2.6e-71 239.7 0.0 2e-69 233.5 0.0 2.6 3 0 0 3 3 3 2 Putative undecaprenyl diphosphate synthase Terpene_synth_C PF03936.16 KFX89587.1 - 0.0036 16.7 0.1 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Crystall_3 PF08964.10 KFX89588.1 - 0.0032 17.6 0.0 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 Beta/Gamma crystallin Crystall PF00030.19 KFX89588.1 - 0.031 14.5 0.1 1.6 9.0 0.0 2.4 2 1 0 2 2 2 0 Beta/Gamma crystallin adh_short PF00106.25 KFX89589.1 - 3.2e-32 111.6 0.6 8.8e-32 110.1 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89589.1 - 4.5e-30 104.9 1.8 1e-28 100.5 1.8 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89589.1 - 1e-08 35.3 0.1 2.2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFX89589.1 - 0.00027 21.2 0.2 0.00077 19.7 0.2 1.7 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFX89589.1 - 0.005 16.0 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX89589.1 - 0.077 12.4 0.2 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.21 KFX89591.1 - 1.1e-71 241.4 0.1 1.6e-71 240.9 0.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 KFX89591.1 - 3.1e-31 108.7 1.3 3.3e-31 108.6 0.2 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Condensation PF00668.20 KFX89591.1 - 0.00029 19.7 0.0 0.00046 19.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain p450 PF00067.22 KFX89592.1 - 1.5e-67 228.3 0.0 2.5e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFX89592.1 - 3.9e-37 128.0 24.1 3.9e-37 128.0 24.1 5.5 2 2 2 5 5 5 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 KFX89592.1 - 1.2e-33 116.6 38.4 1.2e-33 116.6 38.4 2.6 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 KFX89592.1 - 2.6e-17 62.7 0.0 4.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89592.1 - 2.3e-05 24.4 11.6 4.2e-05 23.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MWFE PF15879.5 KFX89592.1 - 0.13 12.4 0.0 0.86 9.8 0.0 2.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit Amidase PF01425.21 KFX89593.1 - 6.2e-74 249.6 0.1 4e-73 246.9 0.1 1.9 1 1 0 1 1 1 1 Amidase LIP PF03583.14 KFX89594.1 - 8e-61 205.9 0.7 1.1e-60 205.4 0.7 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KFX89594.1 - 1e-06 28.4 0.2 0.00014 21.4 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFX89594.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KFX89594.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFX89594.1 - 0.061 12.6 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX89594.1 - 0.13 11.9 0.2 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold BNR_2 PF13088.6 KFX89595.1 - 0.04 13.2 0.1 0.23 10.8 0.1 2.1 1 1 1 2 2 2 0 BNR repeat-like domain Helicase_C PF00271.31 KFX89596.1 - 2.6e-05 24.5 0.0 3.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_7 PF00840.20 KFX89597.1 - 7.9e-84 281.9 23.8 3e-28 98.7 6.4 5.0 2 1 2 4 4 4 4 Glycosyl hydrolase family 7 Peptidase_A4 PF01828.17 KFX89598.1 - 1.9e-74 249.6 20.1 2.4e-74 249.4 20.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family HLH PF00010.26 KFX89605.1 - 2.7e-16 59.3 0.2 5.2e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 KFX89605.1 - 0.043 13.9 0.5 0.043 13.9 0.5 1.8 2 0 0 2 2 2 0 bZIP transcription factor YkyA PF10368.9 KFX89605.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Choline_kinase PF01633.20 KFX89607.1 - 2.5e-48 164.5 0.0 3e-47 161.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KFX89607.1 - 3.5e-09 37.0 0.8 5.6e-09 36.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX89607.1 - 0.028 13.7 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase PEX11 PF05648.14 KFX89611.1 - 1.6e-70 237.0 0.1 1.8e-70 236.9 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) CesT PF05932.13 KFX89612.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Dyp_perox PF04261.12 KFX89612.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family p450 PF00067.22 KFX89614.1 - 4.3e-52 177.4 0.0 5.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad4 PF03835.15 KFX89615.1 - 5.5e-31 107.2 0.3 5.5e-31 107.2 0.3 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFX89615.1 - 4.8e-27 94.2 0.1 9e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KFX89615.1 - 1e-16 61.6 2.3 8.2e-16 58.7 0.1 3.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KFX89615.1 - 1.5e-16 59.9 0.0 3.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Autophagy_N PF03986.13 KFX89615.1 - 0.98 9.4 5.5 0.78 9.7 0.1 2.6 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain Glyco_transf_17 PF04724.13 KFX89623.1 - 3.9e-48 164.3 3.3 5.9e-48 163.7 3.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 DUF3530 PF12048.8 KFX89623.1 - 0.032 13.7 0.2 0.056 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Fungal_trans_2 PF11951.8 KFX89624.1 - 2.4e-10 39.8 0.6 3.8e-10 39.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89624.1 - 0.00013 22.0 8.6 0.00034 20.7 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3323 PF11796.8 KFX89624.1 - 0.057 13.3 0.9 0.095 12.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF4336 PF14234.6 KFX89625.1 - 9.2e-14 51.4 0.0 3.5e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4566 PF15130.6 KFX89625.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Aldo_ket_red PF00248.21 KFX89626.1 - 5.3e-48 163.7 0.0 6.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 KFX89626.1 - 0.033 14.7 0.1 14 6.2 0.0 2.8 2 0 0 2 2 2 0 Glycosyl hydrolase 108 MFS_1 PF07690.16 KFX89627.1 - 1.7e-42 145.6 47.4 1.7e-42 145.6 47.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89629.1 - 8.1e-84 282.1 28.8 9.3e-84 281.9 28.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89629.1 - 2.1e-25 89.4 26.1 2.1e-25 89.4 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1270 PF06900.11 KFX89629.1 - 0.06 13.7 0.2 0.06 13.7 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1270) TauD PF02668.16 KFX89630.1 - 1.5e-43 149.5 0.0 1.9e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M35 PF02102.15 KFX89631.1 - 3.1e-93 312.5 18.7 3.6e-93 312.3 18.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KFX89631.1 - 1.3e-40 139.3 7.0 2.2e-40 138.5 7.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KFX89631.1 - 2.9e-05 23.8 2.6 2.9e-05 23.8 2.6 1.7 2 1 0 2 2 2 1 Putative peptidase family Ntox43 PF15537.6 KFX89632.1 - 0.068 13.2 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 43 Aldedh PF00171.22 KFX89635.1 - 1.1e-121 406.6 0.5 1.4e-121 406.3 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 KFX89635.1 - 6.8e-16 58.1 45.4 6.8e-16 58.1 45.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89635.1 - 0.00092 18.2 13.7 0.00092 18.2 13.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter UPF0093 PF03653.13 KFX89635.1 - 0.047 13.9 6.2 0.11 12.7 6.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) SurE PF01975.17 KFX89636.1 - 2.8e-38 131.7 0.0 3.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Transp_cyt_pur PF02133.15 KFX89637.1 - 3.5e-142 474.2 34.8 4e-142 474.1 34.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OTT_1508_deam PF14441.6 KFX89638.1 - 4.4e-20 71.5 0.2 9.1e-20 70.4 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase TMEM52 PF14979.6 KFX89638.1 - 0.034 14.1 2.6 1.3 8.9 1.4 2.5 2 0 0 2 2 2 0 Transmembrane 52 Epimerase PF01370.21 KFX89639.1 - 9.3e-15 54.7 0.0 1.8e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX89639.1 - 3.3e-12 46.5 0.0 6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX89639.1 - 1.1e-07 31.4 0.0 7.8e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFX89639.1 - 0.00011 21.4 0.0 0.00025 20.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX89639.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX89639.1 - 0.017 14.7 0.1 0.06 12.9 0.1 1.9 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 KFX89639.1 - 0.018 15.0 0.1 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 KR domain SH3_3 PF08239.11 KFX89640.1 - 0.0063 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Stomagen PF16851.5 KFX89640.1 - 0.045 13.8 1.1 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Stomagen ABC_tran PF00005.27 KFX89641.1 - 4.2e-39 134.2 0.0 1.9e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX89641.1 - 3.3e-25 89.3 11.2 3.3e-25 89.3 11.2 2.7 3 0 0 3 3 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 KFX89641.1 - 3.5e-10 40.2 6.9 0.02 14.7 0.0 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX89641.1 - 4.3e-10 39.4 1.6 0.036 13.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX89641.1 - 3.7e-07 30.5 0.1 0.016 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX89641.1 - 1.6e-06 27.7 0.9 0.05 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KFX89641.1 - 4.6e-06 25.9 0.1 0.0041 16.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KFX89641.1 - 1.1e-05 25.9 0.1 0.038 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX89641.1 - 1.6e-05 24.9 0.3 0.042 13.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX89641.1 - 3.6e-05 23.8 0.2 0.22 11.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFX89641.1 - 9.6e-05 23.0 0.8 0.38 11.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KFX89641.1 - 0.00017 21.7 0.3 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.6 KFX89641.1 - 0.00035 21.1 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFX89641.1 - 0.00088 19.1 0.0 0.97 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KFX89641.1 - 0.0012 19.0 0.5 0.2 11.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KFX89641.1 - 0.0014 18.8 1.9 0.078 13.1 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KFX89641.1 - 0.0016 18.2 0.5 13 5.5 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX89641.1 - 0.0023 17.5 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFX89641.1 - 0.003 16.9 0.2 0.69 9.2 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.29 KFX89641.1 - 0.0037 17.7 0.1 0.62 10.5 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFX89641.1 - 0.0052 16.4 0.3 3.1 7.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KFX89641.1 - 0.014 14.6 0.0 6.8 5.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 KFX89641.1 - 0.016 15.4 3.7 1.6 9.0 0.5 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 KFX89641.1 - 0.02 14.7 0.2 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KFX89641.1 - 0.029 14.0 1.7 0.49 10.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 KFX89641.1 - 0.034 13.0 0.2 4.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 KFX89641.1 - 0.041 13.2 0.1 0.84 8.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KFX89641.1 - 0.041 13.8 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 KFX89641.1 - 0.05 13.0 0.5 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFX89641.1 - 0.054 13.9 0.1 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 KFX89641.1 - 0.066 12.9 0.1 1 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 KFX89641.1 - 0.091 11.7 0.1 0.91 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.9 KFX89641.1 - 0.1 12.3 0.5 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 KFX89641.1 - 0.11 12.5 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 KFX89641.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase AAA_5 PF07728.14 KFX89641.1 - 0.19 11.7 0.2 16 5.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 KFX89641.1 - 0.21 11.4 0.8 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FAD_binding_3 PF01494.19 KFX89642.1 - 1.8e-16 60.3 0.3 9.2e-15 54.7 0.4 2.7 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFX89642.1 - 0.0022 18.2 0.0 0.0091 16.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KFX89643.1 - 3.3e-58 194.2 5.8 8.8e-15 55.1 0.2 10.6 6 4 4 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX89643.1 - 1.1e-45 153.4 2.1 6e-08 33.1 0.0 13.4 10 2 4 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89643.1 - 2.4e-45 147.3 13.4 0.00085 19.6 0.1 16.9 17 2 0 17 17 17 9 Ankyrin repeat Ank PF00023.30 KFX89643.1 - 1.2e-29 101.4 18.0 0.0035 17.7 0.3 15.0 18 0 0 18 18 18 7 Ankyrin repeat Ank_5 PF13857.6 KFX89643.1 - 8.8e-21 73.7 10.7 0.00013 22.1 0.2 9.3 6 4 4 10 10 10 6 Ankyrin repeats (many copies) Clr5 PF14420.6 KFX89643.1 - 1.7e-15 57.0 0.1 4.2e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain TGS PF02824.21 KFX89643.1 - 0.02 14.9 0.0 0.072 13.1 0.0 2.0 1 0 0 1 1 1 0 TGS domain DUF2205 PF10224.9 KFX89646.1 - 5.8e-37 125.5 2.3 8.7e-37 125.0 2.3 1.3 1 0 0 1 1 1 1 Short coiled-coil protein Cbl_N PF02262.16 KFX89646.1 - 0.0071 16.4 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Spectrin PF00435.21 KFX89646.1 - 0.026 15.0 1.3 0.041 14.4 1.3 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF4208 PF13907.6 KFX89646.1 - 0.048 14.1 0.6 0.067 13.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) SapC PF07277.11 KFX89646.1 - 0.07 12.7 0.1 0.093 12.3 0.1 1.1 1 0 0 1 1 1 0 SapC DUF908 PF06012.12 KFX89646.1 - 2.5 7.4 8.5 3 7.2 8.5 1.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) NDUF_B8 PF05821.11 KFX89648.1 - 4.2e-06 26.7 0.1 5.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DHDPS PF00701.22 KFX89654.1 - 3e-34 118.1 0.0 3.5e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 KFX89655.1 - 2.9e-11 44.2 0.4 1.4e-10 42.1 0.4 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KFX89655.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain HAD_2 PF13419.6 KFX89656.1 - 3.6e-20 72.8 0.0 6.8e-20 71.9 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX89656.1 - 3.8e-08 33.9 0.1 5.9e-07 30.0 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX89656.1 - 4e-06 26.8 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KFX89656.1 - 0.0003 20.6 0.0 0.017 14.9 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Oxidored_FMN PF00724.20 KFX89660.1 - 1.3e-81 274.5 0.0 2.3e-48 165.2 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 KFX89661.1 - 7.6e-20 71.0 0.4 1.6e-19 70.0 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89661.1 - 3.9e-07 30.1 10.9 7.5e-07 29.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KFX89661.1 - 0.0033 17.2 3.4 0.01 15.7 3.4 1.9 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat adh_short_C2 PF13561.6 KFX89662.1 - 2.9e-51 174.3 0.5 3.6e-51 174.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX89662.1 - 3.6e-42 144.0 0.5 4.4e-42 143.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX89662.1 - 7.7e-10 39.0 0.6 1e-09 38.6 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX89662.1 - 0.011 15.2 0.2 0.021 14.3 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cellulase PF00150.18 KFX89663.1 - 2e-19 70.1 2.9 2e-19 70.1 2.9 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFX89663.1 - 1.4e-12 47.3 13.2 3.5e-12 46.0 13.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KFX89663.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DNMT1-RFD PF12047.8 KFX89663.1 - 0.0019 18.2 0.3 0.02 14.9 0.1 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain DUF1643 PF07799.12 KFX89663.1 - 0.0044 17.2 0.3 0.0095 16.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1643) Glyco_hydro_42 PF02449.15 KFX89663.1 - 0.057 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase AA_permease_2 PF13520.6 KFX89673.1 - 2.3e-53 181.6 59.3 2.9e-53 181.2 59.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX89673.1 - 2.6e-22 79.1 50.3 3.8e-22 78.5 50.3 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 KFX89674.1 - 1.1e-50 172.7 0.0 1.6e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KFX89676.1 - 1.4e-17 63.6 0.0 3.1e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89676.1 - 9.2e-07 28.9 11.0 1.5e-06 28.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX89677.1 - 1.7e-18 66.8 0.0 7.6e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89677.1 - 1e-12 48.1 0.0 6.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89677.1 - 7.3e-06 26.0 0.1 2.5e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFX89677.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 KFX89677.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B DDE_3 PF13358.6 KFX89678.1 - 1.5e-09 37.8 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 KFX89678.1 - 0.0048 17.5 0.3 0.016 15.8 0.2 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 KFX89678.1 - 0.0083 16.3 0.0 0.04 14.2 0.0 2.2 1 1 1 2 2 2 1 Transposase MBOAT_2 PF13813.6 KFX89679.1 - 1.2e-19 70.3 2.2 2.8e-19 69.2 2.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Amidase PF01425.21 KFX89680.1 - 4.3e-96 322.6 0.0 1.1e-95 321.2 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF1822 PF08852.11 KFX89681.1 - 0.068 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF3732 PF12532.8 KFX89681.1 - 0.069 12.7 0.3 0.19 11.2 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3732) Fungal_trans_2 PF11951.8 KFX89682.1 - 6.4e-52 176.6 7.7 8e-52 176.3 7.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89682.1 - 5.1e-09 36.1 9.8 9.1e-09 35.3 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS-DH PF14765.6 KFX89682.1 - 0.0092 15.2 0.3 0.08 12.2 0.1 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase PSI_integrin PF17205.3 KFX89682.1 - 2.2 8.1 9.0 2.7 7.8 7.2 2.1 1 1 1 2 2 2 0 Integrin plexin domain Arginase PF00491.21 KFX89683.1 - 1.2e-92 310.4 0.0 1.4e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KFX89683.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MFS_1 PF07690.16 KFX89684.1 - 1.5e-46 159.0 29.8 2.4e-44 151.7 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89684.1 - 6.1e-17 61.6 26.5 9.5e-16 57.7 26.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFX89684.1 - 1.1e-05 24.1 2.4 1.7e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFX89684.1 - 0.0038 15.7 1.2 0.0076 14.7 1.2 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.15 KFX89684.1 - 0.027 13.5 15.5 0.014 14.4 5.1 2.6 2 1 1 3 3 3 0 PUCC protein OATP PF03137.20 KFX89684.1 - 0.036 12.3 7.6 0.14 10.4 1.6 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.22 KFX89685.1 - 8.3e-178 591.6 0.5 9.4e-178 591.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFX89685.1 - 0.0035 16.8 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Potass_KdpF PF09604.10 KFX89690.1 - 0.038 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Glyco_hydro_11 PF00457.17 KFX89691.1 - 2.8e-83 277.9 16.0 3.2e-83 277.7 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.11 KFX89691.1 - 0.042 14.0 0.6 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Bac_rhamnosid6H PF17389.2 KFX89692.1 - 5.3e-18 65.4 2.3 1.4e-16 60.7 0.6 2.3 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFX89692.1 - 4.6e-16 58.4 1.5 1.1e-15 57.1 1.5 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain F5_F8_type_C PF00754.25 KFX89692.1 - 1.4e-09 38.1 0.2 5.1e-09 36.3 0.2 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF608 PF04685.13 KFX89692.1 - 6.2e-07 28.9 0.7 1.2e-06 27.9 0.7 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region GDE_C PF06202.14 KFX89692.1 - 3.1e-05 23.1 0.1 5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KFX89692.1 - 0.00014 20.8 0.1 0.00022 20.2 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KFX89692.1 - 0.0052 15.5 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KFX89692.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_63 PF03200.16 KFX89692.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Glyco_transf_90 PF05686.12 KFX89698.1 - 1.7e-14 53.6 2.7 1.5e-11 43.9 0.6 3.7 2 1 0 2 2 2 1 Glycosyl transferase family 90 Get5_C PF18514.1 KFX89698.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 Get5 C-terminal domain Ribosomal_L27A PF00828.19 KFX89699.1 - 1.3e-29 103.4 1.4 2.1e-29 102.8 1.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 4HBT_3 PF13622.6 KFX89700.1 - 6.5e-28 98.6 0.2 8.2e-28 98.3 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFX89700.1 - 9.7e-09 35.2 0.0 6.9e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribonuc_L-PSP PF01042.21 KFX89701.1 - 6.4e-18 64.9 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP PX PF00787.24 KFX89701.1 - 1.1e-17 64.0 0.2 2.3e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 KFX89701.1 - 0.042 13.9 0.2 0.085 12.9 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit Tmemb_cc2 PF10267.9 KFX89701.1 - 0.18 10.9 0.6 0.28 10.3 0.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SnoaL PF07366.12 KFX89702.1 - 1.7e-29 102.2 0.1 2e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFX89702.1 - 3.6e-15 56.4 0.1 4.4e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Chromo PF00385.24 KFX89703.1 - 0.00014 21.7 2.7 0.21 11.5 0.1 3.2 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DYW_deaminase PF14432.6 KFX89703.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Mtf2_C PF14061.6 KFX89703.1 - 0.018 15.2 3.5 1 9.6 0.0 2.9 3 0 0 3 3 3 0 Polycomb-like MTF2 factor 2 Ribosomal_S19e PF01090.19 KFX89704.1 - 2.4e-58 195.7 0.2 2.8e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 KFX89705.1 - 1.3e-20 74.9 0.0 3.4e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX89705.1 - 2.4e-17 63.4 0.0 1.2e-16 61.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX89705.1 - 1.6e-13 50.5 0.0 2.4e-12 46.6 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DSPc PF00782.20 KFX89705.1 - 6.6e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KFX89705.1 - 1.2e-07 32.1 0.1 6.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KFX89705.1 - 4.5e-05 23.3 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 KFX89705.1 - 0.0001 22.5 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Esterase PF00756.20 KFX89705.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Y_phosphatase PF00102.27 KFX89705.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 KFX89705.1 - 0.0024 17.8 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 KFX89705.1 - 0.039 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 KFX89705.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 KFX89705.1 - 0.072 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KFX89705.1 - 0.088 12.6 0.0 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KFX89705.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 KFX89705.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF676 PF05057.14 KFX89705.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 KFX89705.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.18 KFX89705.1 - 0.19 11.2 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3632 PF12311.8 KFX89706.1 - 5.9e-20 72.4 0.0 7.6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.11 KFX89707.1 - 3.1e-30 105.5 0.3 6.6e-30 104.4 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_4 PF13418.6 KFX89711.1 - 7.9e-34 115.4 7.2 1.8e-06 27.8 0.0 6.7 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KFX89711.1 - 4.6e-29 99.7 9.3 1.3e-09 38.0 1.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFX89711.1 - 3.5e-28 97.3 10.3 1e-05 25.7 0.1 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFX89711.1 - 1.5e-27 95.0 8.8 1.1e-07 31.6 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFX89711.1 - 9.5e-26 89.1 7.6 2.6e-08 33.3 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFX89711.1 - 1.7e-19 68.9 10.0 3.5e-06 26.8 0.7 6.5 6 0 0 6 6 6 4 Kelch motif LRR_8 PF13855.6 KFX89712.1 - 1.1e-06 28.3 1.5 3.4e-06 26.7 1.5 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFX89712.1 - 0.00017 21.9 1.6 0.16 12.4 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Phosducin PF02114.16 KFX89713.1 - 3.3e-10 39.4 0.1 5e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin Ribosomal_S27e PF01667.17 KFX89714.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KFX89714.1 - 0.39 10.7 6.3 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Proteasome PF00227.26 KFX89717.1 - 1.9e-32 112.3 0.0 2.1e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 KFX89718.1 - 2.4e-49 167.3 7.5 2.8e-49 167.1 3.6 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFX89718.1 - 1.1e-46 158.9 10.1 1.7e-46 158.2 6.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX89718.1 - 8.9e-24 84.9 2.4 8.1e-23 81.8 2.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX89718.1 - 1.1e-20 73.6 0.0 2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX89718.1 - 6.8e-18 64.1 0.2 2.3e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX89718.1 - 2.2e-08 34.2 0.7 2e-06 27.8 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX89718.1 - 1.1e-05 25.9 0.0 3.4e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.20 KFX89720.1 - 4.2e-108 360.0 1.6 6.1e-108 359.4 1.6 1.2 1 0 0 1 1 1 1 14-3-3 protein FlaC_arch PF05377.11 KFX89720.1 - 0.16 12.4 1.1 0.34 11.3 1.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MitMem_reg PF13012.6 KFX89720.1 - 0.18 12.2 0.8 1 9.8 0.2 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TP_methylase PF00590.20 KFX89723.1 - 1e-20 74.6 0.1 1.9e-20 73.8 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 KFX89724.1 - 7.1e-08 32.5 0.2 1.2e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX89724.1 - 1.6e-05 25.1 0.4 2.9e-05 24.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KFX89724.1 - 0.00058 19.9 0.7 0.0018 18.3 0.7 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KFX89724.1 - 0.028 14.5 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger Atg14 PF10186.9 KFX89724.1 - 1.4 7.9 8.0 2.3 7.2 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Presenilin PF01080.17 KFX89724.1 - 6.2 5.5 6.7 9.4 4.9 6.7 1.2 1 0 0 1 1 1 0 Presenilin HET PF06985.11 KFX89726.1 - 8.4e-11 42.4 4.1 3e-08 34.2 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 KFX89726.1 - 8.5e-06 25.5 10.0 1.5e-05 24.7 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type FB_lectin PF07367.11 KFX89726.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin C1_2 PF03107.16 KFX89726.1 - 0.056 13.8 7.4 0.12 12.7 7.4 1.5 1 0 0 1 1 1 0 C1 domain HA2 PF04408.23 KFX89726.1 - 0.079 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) zf-MYND PF01753.18 KFX89726.1 - 5.7 7.1 9.0 12 6.1 9.0 1.5 1 0 0 1 1 1 0 MYND finger TFIIA PF03153.13 KFX89727.1 - 0.00028 21.0 37.4 0.00028 21.0 37.4 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SSXT PF05030.12 KFX89727.1 - 0.017 14.7 0.4 0.07 12.8 0.4 2.1 1 1 0 1 1 1 0 SSXT protein (N-terminal region) WD40 PF00400.32 KFX89734.1 - 3.7e-21 75.0 9.7 0.0011 19.7 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89734.1 - 8.7e-17 61.2 0.0 2.7e-06 27.6 0.0 5.4 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX89734.1 - 1.2e-05 25.3 0.2 0.017 15.0 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX89734.1 - 0.0021 17.1 0.0 12 4.7 0.0 4.0 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX89734.1 - 0.0022 17.4 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain PD40 PF07676.12 KFX89734.1 - 0.0057 16.6 0.5 11 6.1 0.1 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KFX89734.1 - 0.021 13.6 0.0 15 4.2 0.0 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SNF2_N PF00176.23 KFX89737.1 - 3.2e-58 197.1 0.0 5.1e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KFX89737.1 - 2.8e-13 50.2 0.0 5.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX89737.1 - 4.9e-05 23.2 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX89737.1 - 0.00013 22.3 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX89737.1 - 0.0017 17.6 0.0 0.0036 16.5 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 KFX89737.1 - 0.017 15.4 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) SWI2_SNF2 PF18766.1 KFX89737.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SpoIIIAH PF12685.7 KFX89738.1 - 6 6.6 18.3 11 5.8 18.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Arfaptin PF06456.13 KFX89745.1 - 0.0027 17.3 0.2 0.0061 16.2 0.2 1.5 1 0 0 1 1 1 1 Arfaptin-like domain IMD PF08397.11 KFX89745.1 - 0.0048 16.3 3.5 0.072 12.5 3.4 2.0 1 1 0 1 1 1 1 IRSp53/MIM homology domain TRI12 PF06609.13 KFX89746.1 - 2.8e-41 141.7 30.2 3.4e-41 141.4 30.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX89746.1 - 7e-22 77.8 58.5 7e-22 77.8 58.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89746.1 - 7.3e-10 38.3 12.6 7.3e-10 38.3 12.6 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Tymo_coat PF00983.18 KFX89746.1 - 0.082 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Tymovirus coat protein Fer4_23 PF18009.1 KFX89753.1 - 0.15 12.5 0.9 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain ERM PF00769.19 KFX89754.1 - 0.015 15.1 0.5 0.027 14.3 0.1 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FAD_binding_3 PF01494.19 KFX89757.1 - 8.6e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFX89757.1 - 0.0035 16.4 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase PGA2 PF07543.12 KFX89764.1 - 2.8e-37 127.8 2.5 3.5e-37 127.4 2.5 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 FliT PF05400.13 KFX89764.1 - 0.027 15.3 1.3 0.027 15.3 1.3 1.9 1 1 0 2 2 2 0 Flagellar protein FliT Thymidylat_synt PF00303.19 KFX89766.1 - 2.1e-106 354.9 0.0 2.5e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase EAP30 PF04157.16 KFX89769.1 - 1.1e-41 142.7 0.3 1.4e-41 142.4 0.3 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KFX89769.1 - 1.8e-25 89.0 0.0 2.9e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 KFX89769.1 - 4.5e-24 83.6 2.6 4.5e-24 83.6 2.6 2.6 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KFX89769.1 - 0.00012 22.1 4.2 0.0049 16.9 0.4 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.20 KFX89769.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.18 KFX89769.1 - 0.079 12.3 13.2 0.13 11.6 1.0 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 KFX89769.1 - 0.099 12.7 4.0 0.21 11.7 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFX89769.1 - 0.1 12.3 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein SAC3_GANP PF03399.16 KFX89770.1 - 2.1e-25 89.7 3.8 6.7e-13 48.7 0.3 2.1 1 1 1 2 2 2 2 SAC3/GANP family Fungal_trans PF04082.18 KFX89771.1 - 1.7e-09 37.1 0.0 4.2e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX89771.1 - 2.5e-09 37.1 9.3 3.4e-05 24.1 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFX89771.1 - 7e-08 32.3 7.1 0.0052 16.7 1.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFX89771.1 - 5.8e-07 29.8 9.6 0.0012 19.5 1.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX89771.1 - 1.3e-06 28.5 13.1 0.00011 22.5 3.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KFX89771.1 - 7.3e-05 23.0 4.3 0.042 14.3 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX89771.1 - 8.5e-05 22.7 1.7 0.24 11.7 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding DUF2197 PF09963.9 KFX89771.1 - 0.39 11.0 2.9 0.78 10.1 2.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_11 PF16622.5 KFX89771.1 - 0.46 10.3 4.5 2.3 8.0 0.1 3.1 4 0 0 4 4 4 0 zinc-finger C2H2-type LIM PF00412.22 KFX89771.1 - 6.6 7.0 6.0 5.5 7.3 1.4 2.5 1 1 1 2 2 2 0 LIM domain Methyltransf_25 PF13649.6 KFX89772.1 - 6.6e-10 39.6 0.1 9.4e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89772.1 - 2.4e-07 30.7 0.0 5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89772.1 - 3.9e-07 30.6 0.1 2.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89772.1 - 0.00011 22.8 0.0 0.00029 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX89772.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX89772.1 - 0.048 13.2 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 KFX89772.1 - 0.12 12.4 0.3 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Dala_Dala_lig_C PF07478.13 KFX89772.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus GATA PF00320.27 KFX89780.1 - 1.4e-10 40.6 6.9 3.1e-10 39.5 6.9 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KFX89780.1 - 0.16 12.2 2.3 0.33 11.2 2.3 1.5 1 0 0 1 1 1 0 zinc-ribbon eIF-5a PF01287.20 KFX89783.1 - 3.1e-14 52.8 0.3 4.2e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFX89783.1 - 0.0094 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Aminotran_1_2 PF00155.21 KFX89786.1 - 6.5e-13 48.6 0.0 8.6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX89786.1 - 0.0023 16.8 0.0 0.0061 15.4 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase STIMATE PF12400.8 KFX89787.1 - 2e-41 141.5 3.7 3.7e-41 140.6 3.7 1.4 1 0 0 1 1 1 1 STIMATE family Virul_fac_BrkB PF03631.15 KFX89787.1 - 1.7 8.2 10.1 0.36 10.4 1.4 2.4 2 1 0 2 2 2 0 Virulence factor BrkB RRM_1 PF00076.22 KFX89788.1 - 4.6e-19 68.0 1.3 5.8e-19 67.7 0.3 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX89788.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFX89788.1 - 0.029 14.6 0.1 0.068 13.4 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KFX89788.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Frankia_peptide PF14407.6 KFX89788.1 - 0.047 13.7 0.1 1.7 8.7 0.0 2.7 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF4523 PF15023.6 KFX89788.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) PTR2 PF00854.21 KFX89791.1 - 4.9e-47 160.6 0.3 8.7e-47 159.8 0.3 1.4 1 0 0 1 1 1 1 POT family TssN PF17555.2 KFX89791.1 - 0.18 11.1 1.3 0.52 9.7 0.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN Phage_Mu_Gam PF07352.12 KFX89810.1 - 0.013 15.5 12.8 0.024 14.5 12.8 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein HC2 PF07382.11 KFX89810.1 - 0.11 12.6 20.7 0.18 11.9 20.7 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Cas_DxTHG PF09455.10 KFX89810.1 - 0.44 10.1 3.0 0.65 9.5 3.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Rho_Binding PF08912.11 KFX89810.1 - 0.63 10.9 13.3 3.5 8.5 5.7 2.7 2 0 0 2 2 2 0 Rho Binding Glyco_hydro_62 PF03664.13 KFX89811.1 - 1.8e-157 522.8 17.4 2.2e-157 522.4 17.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KFX89811.1 - 3e-10 39.9 17.1 3e-10 39.9 17.1 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Kelch_5 PF13854.6 KFX89812.1 - 2.2e-05 24.3 0.0 2.2e-05 24.3 0.0 3.0 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.10 KFX89812.1 - 0.00091 18.6 1.2 0.002 17.5 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Romo1 PF10247.9 KFX89812.1 - 0.087 13.2 1.1 0.26 11.7 0.3 2.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RRM_1 PF00076.22 KFX89813.1 - 1.6e-40 136.8 0.0 3.8e-20 71.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX89813.1 - 0.00029 20.9 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif BUD22 PF09073.10 KFX89813.1 - 0.0017 17.8 39.0 0.0025 17.2 39.0 1.4 1 0 0 1 1 1 1 BUD22 Nup35_RRM_2 PF14605.6 KFX89813.1 - 0.012 15.6 0.0 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SOG2 PF10428.9 KFX89813.1 - 6.7 5.8 16.7 7.9 5.5 16.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L37 PF08561.10 KFX89814.1 - 3.3e-40 137.4 0.4 6.7e-40 136.3 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.13 KFX89815.1 - 1.3e-50 171.2 0.0 2.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 TAFII55 protein conserved region YgaB PF14182.6 KFX89815.1 - 0.19 12.1 0.2 0.49 10.8 0.2 1.7 1 1 0 1 1 1 0 YgaB-like protein Alg6_Alg8 PF03155.15 KFX89816.1 - 1.2e-129 433.5 29.3 1.2e-81 275.1 12.6 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family EpsG PF14897.6 KFX89816.1 - 0.74 9.1 19.5 0.28 10.4 16.5 1.8 1 1 1 2 2 2 0 EpsG family Smim3 PF17307.2 KFX89816.1 - 6.5 6.3 7.6 6.4 6.4 0.0 3.3 4 0 0 4 4 4 0 Small integral membrane protein 3 2-Hacid_dh_C PF02826.19 KFX89818.1 - 1.4e-52 177.7 0.0 2.5e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX89818.1 - 4.5e-35 120.2 0.4 6.5e-35 119.7 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KFX89818.1 - 0.0003 20.5 0.0 0.0012 18.5 0.0 2.1 1 0 0 1 1 1 1 ACT domain AlaDh_PNT_C PF01262.21 KFX89818.1 - 0.0018 17.6 1.1 0.026 13.8 0.5 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KFX89818.1 - 0.02 15.4 0.0 0.061 13.8 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KFX89818.1 - 0.022 14.8 0.2 0.063 13.3 0.2 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lipase_GDSL_2 PF13472.6 KFX89819.1 - 3.4e-15 56.9 0.3 4.6e-15 56.5 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX89819.1 - 2.1e-05 24.6 0.0 5.6e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFX89819.1 - 0.0021 18.2 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFX89819.1 - 0.0065 15.7 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 OSK domain SH3_1 PF00018.28 KFX89820.1 - 5.8e-39 131.5 6.9 1.2e-13 50.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KFX89820.1 - 1.4e-34 117.7 6.2 5.1e-13 48.7 0.2 3.6 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 KFX89820.1 - 1.7e-34 117.5 0.0 3.3e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KFX89820.1 - 2.2e-25 88.1 0.4 4.4e-08 32.7 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 KFX89820.1 - 4.9e-05 23.3 0.3 0.029 14.4 0.1 3.3 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KFX89820.1 - 6.6e-05 23.1 5.8 0.028 14.7 0.8 3.3 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_4 PF18017.1 KFX89820.1 - 0.00035 20.5 0.0 0.00085 19.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_1 PF00515.28 KFX89821.1 - 1.9e-21 74.9 1.7 2.7e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX89821.1 - 3.3e-19 67.4 6.3 8.6e-05 22.4 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFX89821.1 - 5.8e-15 55.7 9.0 8.8e-06 26.3 0.3 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX89821.1 - 2.7e-14 52.7 6.1 0.00033 21.2 0.4 6.0 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX89821.1 - 3.2e-14 51.9 2.5 0.00028 20.9 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX89821.1 - 7.8e-13 47.9 5.5 7.7e-05 22.3 0.0 5.6 4 2 2 6 6 6 2 TPR repeat TPR_19 PF14559.6 KFX89821.1 - 5.4e-12 46.0 8.7 0.0027 18.2 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX89821.1 - 6e-11 42.5 4.8 5.6e-06 26.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX89821.1 - 5.6e-10 38.5 6.4 0.02 14.9 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX89821.1 - 6.3e-09 35.6 0.3 1.6 9.3 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFX89821.1 - 9.2e-08 32.1 1.8 0.019 15.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFX89821.1 - 2.1e-07 31.1 4.3 0.008 16.5 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX89821.1 - 5.6e-06 26.5 2.1 0.00042 20.5 0.2 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFX89821.1 - 0.0059 16.6 0.0 8.2 6.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KFX89821.1 - 0.0069 15.4 0.0 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_6 PF13174.6 KFX89821.1 - 0.0079 16.8 9.9 27 5.7 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX89821.1 - 0.02 14.7 0.5 0.02 14.7 0.5 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 KFX89821.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_15 PF13429.6 KFX89821.1 - 0.35 10.0 8.4 1.7 7.8 0.3 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFX89821.1 - 0.51 10.8 4.6 29 5.1 0.1 3.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain ODC_AZ PF02100.17 KFX89829.1 - 6e-41 139.0 0.1 8.7e-41 138.5 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1811 PF08838.10 KFX89829.1 - 0.22 11.8 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) TFIIIC_sub6 PF10419.9 KFX89830.1 - 1.6e-25 88.8 0.0 3e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain DUF4653 PF15546.6 KFX89830.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Alk_phosphatase PF00245.20 KFX89833.1 - 2.6e-69 234.2 0.5 3e-68 230.7 0.5 2.0 1 1 0 1 1 1 1 Alkaline phosphatase SKG6 PF08693.10 KFX89833.1 - 5.8e-06 25.6 0.7 1.8e-05 24.1 0.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sulfatase PF00884.23 KFX89833.1 - 9.6e-06 25.2 0.1 1.7e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFX89833.1 - 1e-05 25.3 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFX89833.1 - 0.0031 16.2 0.2 0.0031 16.2 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KFX89833.1 - 0.13 11.6 0.8 6.8 6.0 0.2 2.4 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF1501 PF07394.12 KFX89833.1 - 0.15 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_S64 PF08192.11 KFX89836.1 - 0.0023 16.5 0.2 0.0056 15.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S7 PF00949.21 KFX89836.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 1 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Ecm33 PF12454.8 KFX89844.1 - 4.1e-08 33.2 0.2 1.2e-07 31.7 0.2 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 KFX89844.1 - 1.8e-06 28.0 2.5 0.55 10.4 0.0 4.5 1 1 4 5 5 5 3 Receptor L domain UCR_14kD PF02271.16 KFX89847.1 - 1.6e-44 149.9 0.0 1.9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Trypsin_2 PF13365.6 KFX89850.1 - 0.11 13.5 0.0 0.24 12.3 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 KFX89850.1 - 0.15 10.5 0.2 0.23 9.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DSPc PF00782.20 KFX89851.1 - 9.7e-19 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX89851.1 - 0.0015 18.2 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFX89851.1 - 0.0093 16.0 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 KFX89851.1 - 0.044 14.1 0.1 0.19 12.1 0.1 1.9 1 1 0 1 1 1 0 Rit1 DUSP-like domain Mitofilin PF09731.9 KFX89863.1 - 0.15 10.9 0.5 0.19 10.6 0.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.10 KFX89863.1 - 1.1 7.9 4.3 1.2 7.7 4.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ANAPC4_WD40 PF12894.7 KFX89871.1 - 4.1e-18 65.5 4.3 1.1e-06 28.8 0.1 4.4 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX89871.1 - 1.6e-15 57.2 19.6 0.00065 20.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFX89871.1 - 4.4e-07 29.2 0.1 8.8e-05 21.6 0.0 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX89871.1 - 4.1e-06 26.8 0.1 0.0012 18.8 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Methyltransf_23 PF13489.6 KFX89872.1 - 2.3e-15 56.8 0.0 3.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89872.1 - 1e-08 35.8 0.0 2.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89872.1 - 9.1e-08 32.0 0.0 1.1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89872.1 - 4.2e-06 27.3 0.0 1.3e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX89872.1 - 0.00016 21.2 0.0 0.00037 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFX89872.1 - 0.00024 21.8 0.0 0.00082 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX89872.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KFX89872.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KFX89872.1 - 0.0072 15.8 0.1 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KFX89872.1 - 0.0096 16.1 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KFX89872.1 - 0.037 13.4 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KFX89872.1 - 0.055 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DIOX_N PF14226.6 KFX89877.1 - 5.1e-25 88.5 0.0 1.2e-24 87.4 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.32 KFX89877.1 - 5.4e-07 30.2 6.7 0.1 13.5 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89877.1 - 0.0019 18.4 0.1 4.4 7.7 0.1 4.6 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 KFX89878.1 - 2.8e-32 110.8 0.7 3.4e-32 110.5 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KFX89878.1 - 0.023 15.0 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Pkinase PF00069.25 KFX89881.1 - 2.6e-48 164.7 0.0 3.8e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89881.1 - 2.3e-27 95.9 0.0 3.3e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX89881.1 - 0.042 13.2 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.25 KFX89881.1 - 0.17 11.4 1.2 0.23 10.9 0.3 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Kdo PF06293.14 KFX89881.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 KFX89882.1 - 3.7e-06 26.9 8.1 3.7e-06 26.9 8.1 1.6 2 0 0 2 2 2 1 bZIP transcription factor PAP1 PF08601.10 KFX89882.1 - 0.025 14.3 8.0 11 5.6 0.0 2.4 2 1 0 2 2 2 0 Transcription factor PAP1 DDE_5 PF13546.6 KFX89882.1 - 0.031 13.6 0.2 0.048 13.0 0.2 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease bZIP_2 PF07716.15 KFX89882.1 - 0.069 13.2 8.9 0.14 12.3 8.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Na_H_Exchanger PF00999.21 KFX89889.1 - 4.8e-46 157.3 8.4 6.5e-46 156.8 8.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Filament PF00038.21 KFX89889.1 - 0.018 14.6 2.8 0.027 14.0 2.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein AdoMet_MTase PF07757.13 KFX89889.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF1694 PF07997.11 KFX89889.1 - 0.18 11.9 0.3 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) TrkH PF02386.16 KFX89890.1 - 2.1e-142 475.1 2.0 2.1e-142 475.1 2.0 2.1 2 0 0 2 2 2 2 Cation transport protein PHO4 PF01384.20 KFX89892.1 - 1.3e-110 369.6 13.8 1.6e-110 369.4 13.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3435 PF11917.8 KFX89893.1 - 0.0067 15.4 0.0 0.0092 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) E1-E2_ATPase PF00122.20 KFX89894.1 - 4.2e-38 130.7 12.5 8.5e-31 106.9 0.3 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFX89894.1 - 3.3e-24 85.6 10.5 3.3e-24 85.6 10.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX89894.1 - 2.3e-18 67.2 0.1 1.9e-16 61.0 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX89894.1 - 4e-16 58.9 0.0 2e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX89894.1 - 1.4e-07 31.1 0.0 4.2e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX89894.1 - 0.00041 20.2 0.4 0.00087 19.1 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Copper-fist PF00649.18 KFX89913.1 - 1.3e-18 66.2 0.7 2.5e-18 65.2 0.7 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain Bac_rhamnosid6H PF17389.2 KFX89916.1 - 2.5e-126 421.5 0.0 3.3e-126 421.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KFX89916.1 - 1e-55 188.2 0.0 1.8e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KFX89916.1 - 1.6e-24 85.8 0.0 3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KFX89916.1 - 2.8e-24 84.7 0.1 8e-24 83.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain NMT1_2 PF13379.6 KFX89917.1 - 0.048 13.3 0.0 0.052 13.2 0.0 1.0 1 0 0 1 1 1 0 NMT1-like family 1-cysPrx_C PF10417.9 KFX89917.1 - 0.086 12.7 1.2 0.16 11.8 1.2 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Sugar_tr PF00083.24 KFX89920.1 - 4.8e-80 269.6 19.5 6.3e-80 269.2 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89920.1 - 8.5e-31 107.2 26.7 8.5e-31 107.2 26.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX89920.1 - 0.00022 19.8 3.1 0.00034 19.2 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFX89920.1 - 0.03 12.7 2.6 0.05 12.0 2.6 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector AAA_5 PF07728.14 KFX89921.1 - 2.1e-122 403.5 0.0 1.3e-20 73.8 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFX89921.1 - 4.4e-61 203.7 0.2 2e-25 89.0 0.0 5.5 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_7 PF12775.7 KFX89921.1 - 1.3e-32 112.8 1.0 7.7e-06 25.5 0.1 7.2 6 1 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KFX89921.1 - 1.8e-32 111.6 0.6 3.1e-31 107.6 0.1 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 KFX89921.1 - 6.6e-30 104.7 18.1 5.8e-05 23.5 0.1 9.4 8 1 0 8 8 6 6 AAA ATPase domain AAA_3 PF07726.11 KFX89921.1 - 1.1e-28 99.7 0.0 7.8e-11 42.0 0.0 8.2 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFX89921.1 - 7.6e-27 94.3 0.0 0.00044 20.7 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KFX89921.1 - 1.1e-26 93.6 0.0 0.0014 17.7 0.0 8.6 8 1 0 8 8 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KFX89921.1 - 3.3e-25 88.9 1.2 0.002 18.4 0.0 9.2 9 0 0 9 9 7 5 AAA domain Dynein_heavy PF03028.15 KFX89921.1 - 1.4e-24 86.5 0.0 0.00027 21.0 0.0 8.3 9 0 0 9 9 7 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 KFX89921.1 - 9.2e-21 74.5 0.0 0.025 14.7 0.0 7.2 6 0 0 6 6 6 5 AAA domain Sigma54_activat PF00158.26 KFX89921.1 - 8.4e-20 71.1 0.2 0.039 13.7 0.0 6.8 6 0 0 6 6 6 5 Sigma-54 interaction domain TsaE PF02367.17 KFX89921.1 - 1.4e-17 63.8 2.6 0.016 15.2 0.1 6.7 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFX89921.1 - 1.4e-17 64.4 0.1 0.032 14.8 0.0 7.1 6 0 0 6 6 6 3 AAA domain ABC_tran PF00005.27 KFX89921.1 - 1.9e-17 64.0 1.5 0.01 16.3 0.0 7.5 7 0 0 7 7 6 3 ABC transporter AAA_30 PF13604.6 KFX89921.1 - 4.9e-17 62.3 0.3 0.0046 16.7 0.0 7.4 6 1 0 6 6 6 2 AAA domain AAA_14 PF13173.6 KFX89921.1 - 6.3e-17 61.8 0.0 0.022 14.8 0.0 7.6 7 0 0 7 7 6 2 AAA domain RsgA_GTPase PF03193.16 KFX89921.1 - 8e-17 61.6 0.5 0.028 14.3 0.0 6.3 6 0 0 6 6 6 4 RsgA GTPase RNA_helicase PF00910.22 KFX89921.1 - 4.8e-15 55.8 4.0 0.11 12.8 0.0 7.5 7 0 0 7 7 7 3 RNA helicase NACHT PF05729.12 KFX89921.1 - 5.5e-14 52.4 4.3 0.2 11.6 0.1 6.2 5 0 0 5 5 5 4 NACHT domain Sigma54_activ_2 PF14532.6 KFX89921.1 - 1.1e-12 48.2 1.0 0.0013 18.8 0.0 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain Rad17 PF03215.15 KFX89921.1 - 3.2e-12 46.8 0.1 0.34 10.8 0.0 6.5 6 0 0 6 6 6 2 Rad17 P-loop domain T2SSE PF00437.20 KFX89921.1 - 6.2e-11 41.9 1.1 0.16 11.0 0.0 6.3 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFX89921.1 - 7.3e-11 41.6 0.6 0.28 10.9 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain RuvB_N PF05496.12 KFX89921.1 - 1.2e-10 41.3 4.7 0.022 14.5 0.0 7.1 8 0 0 8 8 7 2 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KFX89921.1 - 2.4e-10 40.0 5.0 0.89 8.8 0.0 7.1 7 0 0 7 7 6 1 Zeta toxin IstB_IS21 PF01695.17 KFX89921.1 - 6.5e-10 39.0 0.2 0.52 10.0 0.0 6.2 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_19 PF13245.6 KFX89921.1 - 2.3e-09 37.8 1.8 1.2 9.4 0.1 6.8 6 0 0 6 6 5 1 AAA domain ATPase_2 PF01637.18 KFX89921.1 - 3e-09 37.2 0.0 0.74 9.7 0.0 6.6 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KFX89921.1 - 3.7e-09 36.3 1.7 6.6 6.1 0.0 7.8 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFX89921.1 - 3.8e-09 36.2 0.1 1.2 8.5 0.0 6.3 6 0 0 6 6 6 1 Bacterial TniB protein AAA_25 PF13481.6 KFX89921.1 - 6.7e-09 35.6 1.2 1.6 8.3 0.0 5.8 5 0 0 5 5 5 1 AAA domain AAA_28 PF13521.6 KFX89921.1 - 1.6e-08 35.0 10.0 0.34 11.2 0.1 7.7 8 0 0 8 8 6 1 AAA domain DUF815 PF05673.13 KFX89921.1 - 2.2e-08 33.6 1.6 2.5 7.2 0.0 5.7 6 0 0 6 6 5 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFX89921.1 - 5.9e-08 32.7 0.0 4.3 7.0 0.0 5.9 6 0 0 6 6 5 0 AAA domain SRP54 PF00448.22 KFX89921.1 - 6.4e-08 32.5 4.5 0.88 9.2 0.1 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KFX89921.1 - 7.2e-08 32.3 2.9 0.043 13.6 0.0 5.3 6 0 0 6 6 4 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KFX89921.1 - 8.8e-08 32.2 2.9 4.7 7.3 0.0 6.6 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFX89921.1 - 2.1e-07 30.9 0.1 1.3 8.7 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KFX89921.1 - 1.2e-06 28.7 3.7 9.2 6.5 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KFX89921.1 - 2.5e-06 27.5 6.0 1.6 8.6 0.0 6.0 6 0 0 6 6 5 2 NTPase Thymidylate_kin PF02223.17 KFX89921.1 - 3.6e-06 26.8 0.1 3.5 7.3 0.0 5.7 5 0 0 5 5 5 0 Thymidylate kinase dNK PF01712.19 KFX89921.1 - 1.6e-05 24.9 4.6 8.8 6.1 0.1 5.7 6 0 0 6 6 5 0 Deoxynucleoside kinase Bac_DnaA PF00308.18 KFX89921.1 - 4.9e-05 23.3 1.9 22 4.8 0.0 6.0 6 1 1 7 7 4 0 Bacterial dnaA protein ResIII PF04851.15 KFX89921.1 - 5.4e-05 23.3 0.8 2 8.4 0.0 4.6 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit cobW PF02492.19 KFX89921.1 - 5.8e-05 22.7 4.8 9.9 5.7 0.0 5.7 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 KFX89921.1 - 8.6e-05 21.9 3.1 0.75 8.9 0.0 5.0 6 0 0 6 6 4 1 TIP49 P-loop domain AAA_17 PF13207.6 KFX89921.1 - 0.00011 22.6 7.2 2.6 8.5 0.0 6.2 6 0 0 6 6 5 0 AAA domain PRK PF00485.18 KFX89921.1 - 0.00028 20.7 0.3 3.5 7.3 0.0 5.2 5 0 0 5 5 5 0 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 KFX89921.1 - 0.00033 20.1 0.3 12 5.2 0.0 4.6 4 0 0 4 4 4 0 KaiC CbiA PF01656.23 KFX89921.1 - 0.00062 19.8 4.5 8.8 6.4 0.1 6.1 6 0 0 6 6 6 0 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.9 KFX89921.1 - 0.00098 18.4 0.4 4.6 6.3 0.0 4.0 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 KFX89921.1 - 0.0045 16.2 4.8 24 4.0 0.1 5.4 6 0 0 6 6 5 0 NB-ARC domain PhoH PF02562.16 KFX89921.1 - 0.0047 16.4 1.0 14 5.1 0.0 4.5 5 0 0 5 5 5 0 PhoH-like protein Septin PF00735.18 KFX89921.1 - 0.0072 15.6 1.5 12 5.0 0.0 5.1 6 0 0 6 6 6 0 Septin ATP_bind_1 PF03029.17 KFX89921.1 - 0.0084 15.9 7.6 7.3 6.3 0.1 5.5 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein AAA_9 PF12781.7 KFX89921.1 - 0.0098 15.0 0.0 3.4 6.7 0.0 4.5 6 0 0 6 6 4 0 ATP-binding dynein motor region Cytidylate_kin PF02224.18 KFX89921.1 - 0.011 15.5 1.7 7 6.3 0.1 4.7 5 0 0 5 5 5 0 Cytidylate kinase FtsK_SpoIIIE PF01580.18 KFX89921.1 - 0.013 14.9 3.5 13 5.0 0.1 5.0 5 0 0 5 5 5 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 KFX89921.1 - 0.018 14.9 0.3 14 5.5 0.0 4.1 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 FAA_hydro_N_2 PF18288.1 KFX89921.1 - 0.038 14.4 0.7 1.7 9.1 0.3 3.6 3 0 0 3 3 2 0 Fumarylacetoacetase N-terminal domain 2 GAF_2 PF13185.6 KFX89921.1 - 0.045 14.0 0.0 0.69 10.2 0.0 3.1 3 0 0 3 3 1 0 GAF domain G-alpha PF00503.20 KFX89921.1 - 0.049 12.8 0.3 7.1 5.7 0.0 4.0 4 0 0 4 4 3 0 G-protein alpha subunit AAA_21 PF13304.6 KFX89921.1 - 0.051 13.4 0.3 2.7 7.7 0.0 3.6 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_8 PF12780.7 KFX89921.1 - 0.057 12.7 0.0 13 5.0 0.0 3.7 3 0 0 3 3 2 0 P-loop containing dynein motor region D4 Ras PF00071.22 KFX89921.1 - 0.057 13.0 1.7 44 3.6 0.0 4.6 5 0 0 5 5 4 0 Ras family tRNA_lig_kinase PF08303.11 KFX89921.1 - 0.06 13.4 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 1 0 tRNA ligase kinase domain MobB PF03205.14 KFX89921.1 - 0.065 13.1 5.0 32 4.4 0.0 5.4 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 KFX89921.1 - 0.11 11.4 2.0 28 3.5 0.0 4.0 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain KTI12 PF08433.10 KFX89921.1 - 0.14 11.6 0.8 17 4.7 0.0 4.4 6 0 0 6 6 4 0 Chromatin associated protein KTI12 Guanylate_kin PF00625.21 KFX89921.1 - 0.16 11.6 0.7 16 5.1 0.0 4.1 4 0 0 4 4 4 0 Guanylate kinase MeaB PF03308.16 KFX89921.1 - 0.18 10.7 1.6 17 4.3 0.1 3.1 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KFX89921.1 - 0.45 10.4 2.5 12 5.8 0.0 4.3 5 0 0 5 5 3 0 Adenylylsulphate kinase AAA_23 PF13476.6 KFX89921.1 - 3 8.3 0.0 3 8.3 0.0 8.8 9 1 0 9 9 6 0 AAA domain Dynamin_N PF00350.23 KFX89921.1 - 6.7 6.7 5.6 16 5.5 0.0 4.0 5 0 0 5 5 2 0 Dynamin family Ribosomal_L12 PF00542.19 KFX89922.1 - 2.7e-18 66.1 1.8 2.7e-18 66.1 1.8 2.4 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFX89922.1 - 9.6e-15 54.0 2.4 2.4e-14 52.7 0.1 2.7 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KFX89922.1 - 0.049 13.4 0.3 0.24 11.2 0.1 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F FAD_binding_6 PF00970.24 KFX89923.1 - 1e-27 96.4 0.0 1.8e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFX89923.1 - 1.1e-26 93.6 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFX89923.1 - 0.00049 20.2 0.0 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CFEM PF05730.11 KFX89924.1 - 3.9e-06 26.9 4.6 5.4e-06 26.4 4.6 1.2 1 0 0 1 1 1 1 CFEM domain Epimerase PF01370.21 KFX89925.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX89925.1 - 0.00045 20.2 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX89925.1 - 0.036 13.1 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFX89925.1 - 0.041 13.5 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 KFX89925.1 - 0.05 12.8 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KFX89925.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MARVEL PF01284.23 KFX89926.1 - 3.1e-06 27.3 2.5 3.1e-06 27.3 2.5 2.2 2 0 0 2 2 2 1 Membrane-associating domain DUF4236 PF14020.6 KFX89926.1 - 0.12 12.9 0.2 3.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) Neurochondrin PF05536.11 KFX89927.1 - 1.2e-72 245.3 0.2 1.5e-72 244.9 0.2 1.1 1 0 0 1 1 1 1 Neurochondrin DUF3993 PF13158.6 KFX89927.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Voltage_CLC PF00654.20 KFX89928.1 - 1.2e-84 284.7 38.2 1.2e-84 284.7 38.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFX89928.1 - 0.00041 20.8 0.0 0.011 16.2 0.1 2.4 2 0 0 2 2 2 1 CBS domain Mito_carr PF00153.27 KFX89929.1 - 2.5e-46 155.5 3.8 4.6e-17 61.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DJ-1_PfpI PF01965.24 KFX89930.1 - 6.6e-08 32.5 0.0 2.1e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 KFX89931.1 - 9.5e-44 149.7 64.5 7.1e-37 127.1 24.1 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX89931.1 - 7.8e-16 57.6 13.9 1.1e-15 57.2 13.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX89931.1 - 1.2e-15 57.4 5.7 1.2e-15 57.4 5.7 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Trypan_PARP PF05887.11 KFX89931.1 - 0.41 10.6 3.0 0.8 9.7 3.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gelsolin PF00626.22 KFX89932.1 - 5.6e-37 125.5 0.0 2.1e-12 46.7 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Hemerythrin PF01814.23 KFX89933.1 - 0.00017 22.2 0.0 0.0003 21.4 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sec8_exocyst PF04048.14 KFX89933.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain His_Phos_1 PF00300.22 KFX89934.1 - 1.8e-10 40.9 0.0 5.7e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RAP1 PF07218.11 KFX89934.1 - 1.2 7.3 7.8 2 6.6 7.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FSA_C PF10479.9 KFX89934.1 - 5.5 5.0 11.8 7.5 4.6 11.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hva1_TUDOR PF11160.8 KFX89935.1 - 9.7e-14 51.3 0.2 9.7e-14 51.3 0.2 1.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain NmrA PF05368.13 KFX89936.1 - 2.2e-15 56.8 0.0 1e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX89936.1 - 2e-11 44.1 0.0 2.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX89936.1 - 0.00023 20.7 0.1 0.00087 18.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fucose_iso_C PF02952.17 KFX89936.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain FAD_binding_4 PF01565.23 KFX89937.1 - 6.8e-26 90.7 1.0 1.3e-25 89.8 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX89937.1 - 0.00093 19.2 1.0 0.0037 17.3 1.0 2.1 1 0 0 1 1 1 1 Berberine and berberine like DUF423 PF04241.15 KFX89938.1 - 0.0077 16.4 0.6 0.0077 16.4 0.6 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF423) AMP-binding PF00501.28 KFX89939.1 - 1.2e-87 294.3 0.0 1.4e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GCS PF03074.16 KFX89942.1 - 1.8e-42 146.0 0.1 2.4e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase bZIP_1 PF00170.21 KFX89949.1 - 2.3e-07 30.8 10.5 2.3e-07 30.8 10.5 2.3 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KFX89949.1 - 1.6e-06 28.5 11.9 1.6e-06 28.5 11.9 1.8 1 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFX89949.1 - 5e-06 26.5 9.1 5e-06 26.5 9.1 2.0 3 0 0 3 3 3 1 Basic region leucine zipper YjcZ PF13990.6 KFX89949.1 - 0.56 9.5 7.3 0.86 8.9 7.3 1.2 1 0 0 1 1 1 0 YjcZ-like protein UPF0242 PF06785.11 KFX89949.1 - 3.8 7.6 14.5 6.4 6.8 14.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 KFX89949.1 - 7.7 6.0 9.1 11 5.5 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 KFX89949.1 - 8.9 4.8 7.5 13 4.2 7.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Skp1 PF01466.19 KFX89950.1 - 1.4e-28 98.8 0.2 2.1e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFX89950.1 - 9.4e-21 73.8 0.2 2.3e-20 72.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC_membrane PF00664.23 KFX89951.1 - 9.4e-110 366.6 37.5 7.3e-56 189.8 13.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX89951.1 - 4.2e-66 221.6 0.3 2.4e-31 109.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFX89951.1 - 1.7e-12 47.3 0.0 0.00065 19.2 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX89951.1 - 1.6e-06 27.8 1.2 0.0079 15.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX89951.1 - 2.2e-06 28.2 2.6 0.0066 16.8 0.1 3.2 2 2 1 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX89951.1 - 3.6e-06 27.0 0.0 0.23 11.3 0.0 3.6 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 KFX89951.1 - 0.0001 22.1 0.1 1 9.0 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX89951.1 - 0.00011 21.9 0.5 0.14 11.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFX89951.1 - 0.00013 22.3 0.7 0.6 10.4 0.0 3.9 3 1 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KFX89951.1 - 0.00044 19.2 1.9 0.085 11.6 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 KFX89951.1 - 0.0018 18.7 1.1 24 5.3 0.1 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFX89951.1 - 0.0021 17.8 2.6 2.3 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 KFX89951.1 - 0.0023 17.1 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 KFX89951.1 - 0.0027 18.0 0.2 0.51 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFX89951.1 - 0.0033 17.3 1.8 6.3 6.5 0.0 3.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KFX89951.1 - 0.0035 16.9 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 KFX89951.1 - 0.0056 16.9 2.9 4.1 7.7 0.3 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KFX89951.1 - 0.0069 16.5 1.3 2 8.5 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_5 PF07728.14 KFX89951.1 - 0.013 15.5 0.1 11 6.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFX89951.1 - 0.014 14.7 1.3 5.9 6.1 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.18 KFX89951.1 - 0.02 14.6 0.4 2.4 7.8 0.0 3.2 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KFX89951.1 - 0.027 14.6 0.2 14 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX89951.1 - 0.039 13.7 0.1 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFX89951.1 - 0.065 12.4 0.2 5.1 6.2 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFX89951.1 - 0.079 13.5 2.0 15 6.1 0.0 3.2 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.15 KFX89951.1 - 0.16 11.9 0.1 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KFX89951.1 - 0.16 12.3 0.0 21 5.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KFX89951.1 - 0.42 11.1 2.8 12 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 KFX89965.1 - 6.4e-11 42.6 9.4 0.0054 17.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89965.1 - 0.00012 22.3 0.0 0.1 12.9 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX89965.1 - 0.0018 18.2 0.0 2.9 8.0 0.0 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX89965.1 - 0.16 10.9 0.1 9.5 5.1 0.1 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 KFX89966.1 - 1.4e-08 34.4 0.0 3.7e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX89966.1 - 4.7e-07 29.4 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KFX89966.1 - 0.056 13.2 0.3 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Calcipressin Limkain-b1 PF11608.8 KFX89966.1 - 0.058 13.5 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Limkain b1 SET_assoc PF11767.8 KFX89966.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Glyco_hydro_47 PF01532.20 KFX89967.1 - 6.9e-169 562.6 0.0 8.6e-169 562.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.16 KFX89968.1 - 0.82 8.5 18.1 0.026 13.5 7.7 2.0 1 1 0 2 2 2 0 Major Facilitator Superfamily FSH1 PF03959.13 KFX89969.1 - 7.3e-31 107.5 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFX89969.1 - 0.0026 17.6 0.0 0.009 15.8 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KFX89969.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain HscB_4_cys PF18256.1 KFX89969.1 - 4.1 7.3 6.1 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif LacAB_rpiB PF02502.18 KFX89975.1 - 2e-44 151.0 0.0 2.3e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KFX89975.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS Glyco_hydro_43 PF04616.14 KFX89979.1 - 5.1e-63 213.1 2.9 6.4e-63 212.7 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX89979.1 - 2.5e-13 50.2 0.0 4.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Beta-lactamase PF00144.24 KFX89980.1 - 2.4e-27 96.0 0.1 4.2e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Arginase PF00491.21 KFX89981.1 - 2.4e-85 286.5 0.3 2.9e-85 286.1 0.3 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KFX89981.1 - 0.25 11.6 0.4 0.36 11.1 0.4 1.2 1 0 0 1 1 1 0 UPF0489 domain FAD_binding_4 PF01565.23 KFX89982.1 - 7.5e-21 74.3 2.1 1.1e-20 73.7 0.9 2.0 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KFX89982.1 - 7.9e-06 25.9 0.1 2.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like HeLo PF14479.6 KFX89984.1 - 1.2e-41 142.8 0.0 1.5e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation Imm7 PF15585.6 KFX89984.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 7 Mur_ligase_C PF02875.21 KFX89984.1 - 0.17 12.1 0.2 0.66 10.3 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Pec_lyase_C PF00544.19 KFX89987.1 - 1.3e-18 67.4 9.8 6.5e-17 61.8 9.6 2.7 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX89987.1 - 2.3e-06 27.5 10.6 3.9e-06 26.8 10.6 1.4 1 0 0 1 1 1 1 Right handed beta helix region Mito_carr PF00153.27 KFX89992.1 - 2.8e-29 100.9 8.6 5.7e-16 58.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.6 KFX89992.1 - 0.016 15.3 1.0 0.28 11.4 0.6 2.9 2 2 0 2 2 2 0 Sporulation protein YtrH Corona_S1 PF01600.16 KFX89992.1 - 0.096 11.4 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein Ank_2 PF12796.7 KFX89999.1 - 1.5e-16 60.7 0.8 1.2e-05 25.7 0.1 4.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX89999.1 - 2.3e-14 53.2 7.6 9.1e-07 29.0 0.8 5.3 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX89999.1 - 2.1e-13 50.5 5.2 0.0041 17.7 0.1 6.8 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89999.1 - 1.2e-10 40.6 8.0 0.089 13.4 0.0 7.6 7 1 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KFX89999.1 - 3.6e-10 39.8 15.3 0.25 11.9 0.1 7.9 7 1 1 8 8 8 4 Ankyrin repeat adh_short PF00106.25 KFX90004.1 - 3.8e-46 157.0 0.1 4.7e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90004.1 - 3.6e-40 138.0 0.3 4.5e-40 137.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90004.1 - 4.1e-12 46.4 0.0 6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX90004.1 - 1e-07 31.7 0.1 2.5e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX90004.1 - 2.2e-06 27.7 0.1 2.9e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFX90004.1 - 6.5e-05 22.2 0.2 0.00013 21.2 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 KFX90004.1 - 0.00017 21.3 0.1 0.00033 20.3 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 KFX90004.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 KFX90004.1 - 0.0054 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF2703 PF10865.8 KFX90004.1 - 0.012 15.8 0.0 0.068 13.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) 3HCDH_N PF02737.18 KFX90004.1 - 0.033 14.1 0.2 0.073 12.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KFX90004.1 - 0.076 13.0 1.0 0.3 11.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HMA PF00403.26 KFX90004.1 - 0.078 13.4 0.7 7.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Heavy-metal-associated domain Sacchrp_dh_NADP PF03435.18 KFX90004.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KFX90005.1 - 2e-34 119.1 51.8 2e-34 119.1 51.8 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX90005.1 - 1.3e-11 44.0 17.8 1.3e-11 44.0 17.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Lip_prot_lig_C PF10437.9 KFX90005.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Fungal_trans PF04082.18 KFX90006.1 - 7.5e-14 51.4 0.1 1.4e-13 50.5 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90006.1 - 5.2e-10 39.3 8.0 1e-09 38.3 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX90007.1 - 6e-35 120.5 0.1 8.3e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90007.1 - 9.6e-23 80.9 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90007.1 - 8.3e-10 38.9 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX90007.1 - 0.021 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FerI PF08151.12 KFX90007.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain Eno-Rase_NADH_b PF12242.8 KFX90007.1 - 0.15 11.8 0.6 0.39 10.5 0.4 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CS PF04969.16 KFX90008.1 - 2.6e-07 31.5 0.2 4.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KFX90008.1 - 0.21 12.2 10.0 0.33 11.5 10.0 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Snf7 PF03357.21 KFX90009.1 - 3.2e-21 75.7 16.4 3.2e-21 75.7 16.4 2.2 2 0 0 2 2 2 1 Snf7 DFRP_C PF16543.5 KFX90010.1 - 3.6e-26 91.5 7.4 3.6e-26 91.5 7.4 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KFX90010.1 - 3.7e-06 27.6 18.4 0.00033 21.3 5.3 3.8 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KFX90010.1 - 4.6e-06 26.4 3.5 4.6e-06 26.4 3.5 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFX90010.1 - 2.7e-05 23.9 11.9 0.0011 18.7 3.8 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFX90010.1 - 3.6e-05 23.7 21.2 0.00089 19.2 9.9 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KFX90010.1 - 0.013 16.0 16.4 0.25 11.9 5.5 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFX90010.1 - 0.63 10.3 8.3 0.74 10.0 2.9 2.6 1 1 0 2 2 2 0 Zinc-finger containing family RRM_1 PF00076.22 KFX90011.1 - 2e-16 59.5 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFX90011.1 - 5.7e-06 26.8 0.6 5.7e-06 26.8 0.6 3.3 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KFX90011.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif CCER1 PF15482.6 KFX90011.1 - 0.037 13.9 2.0 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Sortilin-Vps10 PF15902.5 KFX90012.1 - 1.8e-15 56.7 7.7 0.00022 20.2 0.3 5.7 4 2 1 6 6 6 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFX90012.1 - 1.1e-12 45.9 19.6 0.29 11.3 0.0 9.3 8 0 0 8 8 8 5 BNR/Asp-box repeat CBM_1 PF00734.18 KFX90012.1 - 4.9e-10 39.2 10.1 4.9e-10 39.2 10.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR_6 PF15899.5 KFX90012.1 - 0.00044 20.0 5.5 8.5 6.7 0.0 6.5 7 0 0 7 7 7 1 BNR-Asp box repeat PSII_BNR PF14870.6 KFX90012.1 - 0.0036 16.6 15.3 1.4 8.1 0.1 6.1 5 2 0 5 5 5 3 Photosynthesis system II assembly factor YCF48 Pollen_allerg_1 PF01357.21 KFX90012.1 - 0.06 13.4 0.7 8.7 6.4 0.0 3.8 3 1 1 4 4 4 0 Pollen allergen DUF2452 PF10504.9 KFX90012.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Fungal_trans PF04082.18 KFX90013.1 - 2.2e-32 112.2 0.1 5.6e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90013.1 - 1.5e-08 34.6 15.2 2.5e-08 33.9 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L26 PF16906.5 KFX90014.1 - 4e-38 129.8 3.3 5.4e-38 129.3 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFX90014.1 - 1.6e-08 34.2 0.5 3.7e-08 33.0 0.5 1.7 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KFX90014.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) adh_short PF00106.25 KFX90015.1 - 8.4e-23 80.8 0.1 1.2e-22 80.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90015.1 - 3.1e-19 69.5 0.0 4.6e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90015.1 - 3.8e-05 23.7 0.0 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 KR domain DUF883 PF05957.13 KFX90016.1 - 0.00093 19.8 1.1 0.00093 19.8 1.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) OmpH PF03938.14 KFX90016.1 - 0.0021 18.4 0.6 0.0021 18.4 0.6 1.8 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF4559 PF15112.6 KFX90016.1 - 0.0064 16.2 2.1 0.0064 16.2 2.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4559) Tup_N PF08581.10 KFX90016.1 - 0.097 13.0 0.2 0.097 13.0 0.2 2.8 1 1 2 3 3 3 0 Tup N-terminal NMD3 PF04981.13 KFX90017.1 - 0.04 13.4 1.5 0.068 12.6 1.5 1.2 1 0 0 1 1 1 0 NMD3 family CNDH2_C PF16858.5 KFX90017.1 - 2.5 7.9 12.1 0.81 9.5 8.3 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CinA PF02464.17 KFX90019.1 - 1.3e-15 57.3 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein DUF155 PF02582.14 KFX90020.1 - 2.7e-54 183.9 0.1 3.9e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1218 PF06749.12 KFX90020.1 - 0.017 15.6 0.2 0.048 14.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) ECSCR PF15820.5 KFX90020.1 - 0.057 13.2 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator cNMP_binding PF00027.29 KFX90026.1 - 8.7e-41 137.9 0.0 2.7e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain p450 PF00067.22 KFX90029.1 - 2.4e-17 62.9 0.0 2.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S-AdoMet_synt_C PF02773.16 KFX90031.1 - 3.9e-67 224.5 0.4 1.1e-66 223.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFX90031.1 - 3.3e-45 153.2 0.0 6.2e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFX90031.1 - 2.8e-43 146.6 0.5 7.2e-43 145.3 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.17 KFX90032.1 - 5.9e-71 239.1 0.0 7e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KFX90032.1 - 0.00048 20.2 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KFX90032.1 - 0.0014 18.5 0.0 0.0044 16.8 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 KFX90032.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX90032.1 - 0.004 17.7 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX90032.1 - 0.0044 17.4 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 KFX90032.1 - 0.0073 15.9 0.0 1.7 8.1 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KFX90032.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX90032.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KFX90032.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA PF00004.29 KFX90032.1 - 0.025 15.0 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX90032.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KFX90032.1 - 0.025 15.0 0.0 0.079 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KFX90032.1 - 0.032 13.8 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFX90032.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFX90032.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 KFX90032.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_30 PF13604.6 KFX90032.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KFX90032.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 KFX90032.1 - 0.058 13.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 KFX90032.1 - 0.06 13.4 0.0 0.066 13.3 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KFX90032.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFX90032.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 KFX90032.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KFX90032.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFX90032.1 - 0.097 13.0 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KFX90032.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF447 PF04289.12 KFX90032.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) PduV-EutP PF10662.9 KFX90032.1 - 0.18 11.5 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ank_2 PF12796.7 KFX90033.1 - 1.9e-55 185.4 3.9 2.4e-14 53.7 0.1 7.3 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX90033.1 - 4.1e-44 148.4 6.4 9e-10 38.9 0.1 9.8 5 4 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX90033.1 - 6.7e-35 118.7 11.2 1.2e-10 41.4 0.1 10.3 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX90033.1 - 6.6e-32 106.0 7.3 4.1e-07 29.8 0.0 13.5 15 1 0 15 15 15 6 Ankyrin repeat Ank PF00023.30 KFX90033.1 - 3.1e-26 90.6 16.4 1.9e-07 31.2 0.0 12.6 12 2 0 12 12 12 5 Ankyrin repeat Nif11 PF07862.11 KFX90033.1 - 0.011 16.0 1.8 13 6.1 0.0 4.9 5 1 1 6 6 6 0 Nif11 domain RTA1 PF04479.13 KFX90034.1 - 1.3e-73 247.0 12.3 1.3e-73 247.0 12.3 1.4 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 KFX90035.1 - 1e-07 31.2 3.0 1.5e-07 30.6 0.3 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain SNF2_N PF00176.23 KFX90036.1 - 3.5e-56 190.4 0.0 5.6e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFX90036.1 - 5.8e-24 83.8 2.7 8.6e-15 54.4 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFX90036.1 - 9.6e-19 67.6 1.1 2.6e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFX90036.1 - 1.6e-18 67.1 0.0 3.9e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX90036.1 - 3.9e-08 32.8 1.4 9.8e-08 31.5 0.1 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KFX90036.1 - 7.1e-08 32.8 4.6 1.5e-06 28.5 0.2 5.3 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KFX90036.1 - 9.2e-07 29.0 0.0 6.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KFX90036.1 - 0.00057 19.9 0.0 0.03 14.3 0.0 3.2 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 KFX90036.1 - 0.013 15.7 0.1 0.013 15.7 0.1 3.0 3 1 1 4 4 4 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 KFX90037.1 - 3.6e-33 115.0 0.0 5.6e-15 56.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KFX90037.1 - 9e-14 51.0 5.1 9e-14 51.0 5.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFX90037.1 - 2.4e-11 43.5 1.1 0.0014 18.1 0.1 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX90037.1 - 1e-09 38.6 5.6 0.09 12.6 0.9 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX90037.1 - 1.8e-05 24.6 0.3 0.24 11.1 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 KFX90037.1 - 6.1e-05 23.5 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 KFX90037.1 - 6.4e-05 22.6 3.2 6.4e-05 22.6 3.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.29 KFX90037.1 - 6.6e-05 23.3 0.1 0.059 13.8 0.1 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX90037.1 - 7.8e-05 23.0 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX90037.1 - 0.00023 20.9 0.1 0.064 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX90037.1 - 0.00029 20.8 0.1 0.88 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 KFX90037.1 - 0.0004 20.4 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KFX90037.1 - 0.00062 19.5 0.2 0.62 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFX90037.1 - 0.0011 19.6 0.1 2.6 8.6 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 KFX90037.1 - 0.0012 19.4 0.1 0.18 12.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 KFX90037.1 - 0.0015 18.6 11.7 0.0036 17.4 11.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFX90037.1 - 0.002 18.1 12.5 0.0042 17.1 2.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.22 KFX90037.1 - 0.0025 18.2 1.0 0.68 10.3 0.1 2.8 3 0 0 3 3 2 1 RNA helicase Thymidylate_kin PF02223.17 KFX90037.1 - 0.0037 17.0 1.9 5 6.8 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_13 PF13166.6 KFX90037.1 - 0.0048 15.6 0.4 0.011 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 KFX90037.1 - 0.0054 16.8 15.1 0.021 14.9 1.5 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain TsaE PF02367.17 KFX90037.1 - 0.011 15.7 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFX90037.1 - 0.013 15.5 1.8 0.73 9.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 KFX90037.1 - 0.018 14.7 5.0 0.12 12.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KFX90037.1 - 0.024 13.9 0.0 2.3 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KFX90037.1 - 0.029 14.6 0.3 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFX90037.1 - 0.033 14.4 1.6 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KFX90037.1 - 0.04 14.1 11.2 0.088 13.0 11.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KFX90037.1 - 0.043 13.5 0.4 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 KFX90037.1 - 0.049 14.2 1.5 0.049 14.2 1.5 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFX90037.1 - 0.071 14.1 0.2 0.071 14.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 KFX90037.1 - 0.084 12.9 0.2 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 KFX90037.1 - 0.096 12.4 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 KFX90037.1 - 0.12 12.9 0.2 0.12 12.9 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KFX90037.1 - 0.16 11.3 0.1 0.37 10.1 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KFX90037.1 - 0.19 11.2 0.9 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_8 PF13183.6 KFX90037.1 - 0.54 10.7 6.9 0.42 11.1 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KFX90037.1 - 1.4 8.8 3.2 15 5.5 0.2 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KFX90037.1 - 1.7 8.4 5.7 0.31 10.8 0.3 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 KFX90037.1 - 4.2 7.7 9.7 0.66 10.2 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 KFX90038.1 - 5.2e-50 167.4 14.4 2.8e-15 56.2 0.7 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 KFX90038.1 - 8.2e-17 61.0 14.0 1.5e-09 37.8 1.5 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 KFX90038.1 - 0.25 11.6 5.8 5.4 7.3 0.2 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 KFX90039.1 - 6.4e-111 370.8 0.0 8.7e-111 370.3 0.0 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Fungal_trans PF04082.18 KFX90040.1 - 1.6e-18 66.7 0.0 3.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90040.1 - 3.6e-06 27.0 15.8 6.1e-06 26.2 15.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KFX90040.1 - 0.039 14.0 29.2 0.059 13.4 29.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KFX90041.1 - 2.9e-16 59.3 3.5 3.9e-16 58.9 1.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 KFX90041.1 - 0.012 15.6 9.4 0.033 14.3 9.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MITF_TFEB_C_3_N PF15951.5 KFX90041.1 - 0.07 13.8 10.7 0.14 12.8 10.7 1.5 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Spt20 PF12090.8 KFX90041.1 - 0.3 10.7 9.0 0.5 9.9 9.0 1.3 1 0 0 1 1 1 0 Spt20 family Mpv17_PMP22 PF04117.12 KFX90042.1 - 6.8e-21 74.3 1.9 9.9e-21 73.7 0.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 KFX90043.1 - 2.7e-149 497.3 2.0 3e-149 497.1 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DSS1_SEM1 PF05160.13 KFX90044.1 - 3.2e-23 81.5 17.1 4e-23 81.2 17.1 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 KFX90044.1 - 0.027 14.2 4.9 0.03 14.1 4.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3808 PF10300.9 KFX90045.1 - 1.4e-138 462.6 2.2 1.8e-138 462.2 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) RINGv PF12906.7 KFX90045.1 - 3.8e-05 23.7 7.2 8.7e-05 22.6 7.2 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 KFX90045.1 - 0.0014 18.8 3.5 0.0042 17.2 3.5 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFX90045.1 - 0.039 14.3 6.3 0.079 13.3 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain NST1 PF13945.6 KFX90046.1 - 5.2e-58 196.3 1.5 5.2e-58 196.3 1.5 4.7 4 1 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 KFX90047.1 - 2.4e-48 163.8 0.0 3.3e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX90047.1 - 6.8e-22 77.9 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX90047.1 - 2.1e-06 27.3 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX90047.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFX90047.1 - 0.059 12.8 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFX90047.1 - 0.15 11.8 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MRP-L28 PF09812.9 KFX90048.1 - 0.023 14.8 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 3Beta_HSD PF01073.19 KFX90048.1 - 0.16 10.9 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Filament PF00038.21 KFX90049.1 - 0.0088 15.7 7.0 0.0088 15.7 7.0 5.5 4 1 0 4 4 4 2 Intermediate filament protein DUF4462 PF14692.6 KFX90049.1 - 0.45 10.0 1.5 2.2 7.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) Ank_2 PF12796.7 KFX90066.1 - 1.1e-61 205.3 39.7 4.1e-15 56.1 2.9 8.3 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX90066.1 - 8.3e-50 166.6 14.6 3.6e-10 40.2 0.2 11.2 4 2 7 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX90066.1 - 3.5e-36 122.1 41.1 0.0014 19.0 0.0 14.4 13 1 1 14 14 14 9 Ankyrin repeat Ank_3 PF13606.6 KFX90066.1 - 5.8e-36 118.4 14.9 0.0011 19.2 0.0 14.5 14 0 0 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 KFX90066.1 - 1.2e-30 105.1 30.7 5.1e-07 29.8 1.0 12.9 5 3 9 14 14 14 10 Ankyrin repeats (many copies) Patatin PF01734.22 KFX90066.1 - 8.6e-21 75.1 0.0 2.9e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase NACHT PF05729.12 KFX90066.1 - 1.4e-07 31.6 0.0 7.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 KFX90066.1 - 0.00017 21.6 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KFX90066.1 - 0.00035 21.0 0.0 0.0014 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KFX90066.1 - 0.028 13.6 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 KFX90066.1 - 0.032 14.7 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KFX90066.1 - 0.13 12.6 0.0 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.29 KFX90067.1 - 7.6e-15 55.1 0.0 2.1e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX90067.1 - 3.1e-10 40.3 0.2 1.5e-09 38.1 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX90067.1 - 1e-08 35.5 0.1 2.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KFX90067.1 - 0.075 12.5 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AA_permease PF00324.21 KFX90069.1 - 7.5e-136 453.5 35.2 9.3e-136 453.2 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX90069.1 - 3e-46 158.1 42.1 3.4e-46 157.9 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease C2 PF00168.30 KFX90070.1 - 6.1e-76 251.3 0.3 4.3e-19 68.7 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KFX90070.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain BSP_II PF05432.11 KFX90070.1 - 0.95 9.1 8.2 2 8.1 8.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_L28e PF01778.17 KFX90071.1 - 4.9e-33 114.3 0.4 6.7e-33 113.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family 3-HAO PF06052.12 KFX90077.1 - 3e-09 36.7 0.1 3e-09 36.7 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Ctr PF04145.15 KFX90078.1 - 7.1e-27 94.8 10.7 2.3e-25 89.9 10.7 2.0 1 1 0 1 1 1 1 Ctr copper transporter family MTABC_N PF16185.5 KFX90078.1 - 0.076 12.5 1.1 0.093 12.2 0.8 1.5 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region WD40 PF00400.32 KFX90081.1 - 3.5e-23 81.4 14.6 0.00063 20.5 0.0 10.5 10 1 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90081.1 - 1.3e-05 25.4 6.2 0.022 15.1 0.1 6.2 8 0 0 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX90081.1 - 0.065 12.2 0.1 6.9 5.5 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 KFX90081.1 - 0.11 12.4 0.3 20 5.3 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat Fungal_trans_2 PF11951.8 KFX90083.1 - 8e-54 182.9 1.7 9.5e-54 182.7 1.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain MOR2-PAG1_N PF14222.6 KFX90083.1 - 0.017 14.1 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Aminotran_1_2 PF00155.21 KFX90084.1 - 6.8e-20 71.5 0.0 9e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX90084.1 - 0.00013 20.9 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Axin_b-cat_bind PF08833.10 KFX90084.1 - 0.0018 18.3 0.1 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Axin beta-catenin binding domain AA_permease_2 PF13520.6 KFX90085.1 - 8.4e-48 163.2 51.7 1e-47 162.9 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX90085.1 - 8.7e-27 93.8 44.5 1.3e-26 93.2 44.5 1.2 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 KFX90086.1 - 1.3e-49 169.0 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX90086.1 - 2.6e-10 41.1 0.0 5.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyoxalase PF00903.25 KFX90087.1 - 1.6e-12 47.8 0.0 2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX90087.1 - 4.8e-05 23.6 0.0 0.00013 22.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFX90087.1 - 8.8e-05 22.7 0.1 0.028 14.5 0.1 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 KFX90087.1 - 0.00041 21.1 0.0 0.0012 19.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Pfk_N PF18468.1 KFX90087.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Potex_coat PF06184.11 KFX90088.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein Cucumopine_C PF18631.1 KFX90089.1 - 1.1e-51 174.5 0.0 1.5e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain DUF3830 PF12903.7 KFX90089.1 - 0.08 12.6 0.0 0.98 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) Aminotran_4 PF01063.19 KFX90090.1 - 4.6e-28 98.6 0.0 5.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Nup84_Nup100 PF04121.13 KFX90093.1 - 1.6e-14 53.0 0.0 2e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nucleoporin_FG PF13634.6 KFX90097.1 - 0.0032 18.3 44.4 0.0041 17.9 9.4 12.8 4 3 9 13 13 13 6 Nucleoporin FG repeat region Ku_C PF03730.14 KFX90097.1 - 4.4 8.1 9.8 0.45 11.3 2.8 2.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm PAP2 PF01569.21 KFX90107.1 - 1.2e-13 50.9 0.1 1.2e-13 50.9 0.1 1.9 3 0 0 3 3 3 1 PAP2 superfamily WD40 PF00400.32 KFX90108.1 - 1.5e-18 66.8 2.0 1.2e-06 29.1 0.1 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90108.1 - 0.00011 22.5 0.1 0.13 12.6 0.0 2.6 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3408 PF11888.8 KFX90108.1 - 0.087 13.0 1.3 0.2 11.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3408) Ge1_WD40 PF16529.5 KFX90108.1 - 0.088 11.8 0.1 0.16 10.9 0.1 1.3 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX90108.1 - 0.1 11.3 0.7 4.8 5.7 0.3 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Aminotran_1_2 PF00155.21 KFX90109.1 - 1.3e-60 205.6 0.0 1.9e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 KFX90109.1 - 0.043 14.2 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 AMP-binding PF00501.28 KFX90111.1 - 9.2e-14 50.9 0.0 1.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFX90111.1 - 0.0001 22.2 0.2 0.00023 21.0 0.2 1.6 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TPP_enzyme_N PF02776.18 KFX90112.1 - 7.7e-41 139.6 0.0 1.7e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX90112.1 - 6.5e-36 123.1 0.1 1.5e-35 121.9 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFX90112.1 - 7.2e-20 71.3 0.1 2e-19 69.9 0.1 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 KFX90112.1 - 0.0082 16.2 0.3 0.03 14.4 0.3 2.0 1 0 0 1 1 1 1 B12 binding domain CO_dh PF02552.16 KFX90112.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Nop14 PF04147.12 KFX90113.1 - 9.1e-05 20.9 31.8 0.0001 20.7 31.8 1.2 1 0 0 1 1 1 1 Nop14-like family SH3BGR PF04908.15 KFX90113.1 - 0.00027 21.0 0.0 0.00099 19.2 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein SAPS PF04499.15 KFX90113.1 - 2.7 6.7 17.1 3.3 6.4 17.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.13 KFX90113.1 - 5.8 7.1 27.2 11 6.2 27.2 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated 3Beta_HSD PF01073.19 KFX90114.1 - 1.9e-67 227.2 0.0 2.4e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFX90114.1 - 4.2e-29 101.7 0.1 5.5e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX90114.1 - 1.8e-14 53.5 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX90114.1 - 2.6e-14 53.4 0.2 7e-12 45.4 0.1 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX90114.1 - 5.9e-12 45.3 0.1 1.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFX90114.1 - 2.6e-10 40.5 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX90114.1 - 4.2e-10 39.2 0.5 1e-09 38.0 0.5 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFX90114.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KFX90114.1 - 0.00087 19.5 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFX90114.1 - 0.0014 18.6 0.2 0.0053 16.7 0.2 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 KFX90114.1 - 0.0072 17.0 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyco_trans_4_2 PF13477.6 KFX90114.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like BsuBI_PstI_RE PF06616.11 KFX90114.1 - 0.044 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Guanylate_kin PF00625.21 KFX90114.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase ELMO_CED12 PF04727.13 KFX90115.1 - 5e-50 170.1 0.1 1.1e-49 169.0 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KFX90115.1 - 4.9e-34 117.7 0.0 1.1e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KFX90115.1 - 8.1e-14 51.8 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) RTA1 PF04479.13 KFX90116.1 - 1.1e-53 182.0 9.8 1.1e-53 182.0 9.8 1.4 2 0 0 2 2 2 1 RTA1 like protein Peptidase_M50 PF02163.22 KFX90116.1 - 0.012 14.9 0.1 0.036 13.3 0.1 1.8 1 1 0 1 1 1 0 Peptidase family M50 CBM_1 PF00734.18 KFX90117.1 - 8e-12 44.9 9.7 8e-12 44.9 9.7 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Esterase PF00756.20 KFX90117.1 - 7.7e-06 25.7 0.3 7.9e-05 22.4 0.3 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFX90117.1 - 1.4e-05 24.6 0.1 2.2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFX90117.1 - 0.00074 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KFX90117.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFX90117.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cys_Met_Meta_PP PF01053.20 KFX90118.1 - 5e-29 101.0 0.0 5.9e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NmrA PF05368.13 KFX90119.1 - 2.4e-05 24.0 0.0 0.021 14.4 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family Semialdhyde_dh PF01118.24 KFX90119.1 - 0.0023 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX90119.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KFX90119.1 - 0.019 14.8 0.1 2.6 7.9 0.1 2.4 1 1 1 2 2 2 0 NAD(P)H-binding LtrA PF06772.11 KFX90120.1 - 1.6e-26 93.4 23.6 1.6e-26 93.4 23.6 1.8 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) ApoLp-III PF07464.11 KFX90120.1 - 0.019 15.1 0.4 0.038 14.1 0.4 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PsaL PF02605.15 KFX90120.1 - 0.044 13.4 2.6 3.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI Nsp1_C PF05064.13 KFX90120.1 - 0.1 12.4 0.8 4.9 7.0 0.2 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF5344 PF17279.2 KFX90120.1 - 1 9.9 4.4 3.7 8.2 3.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5344) Alpha-amylase PF00128.24 KFX90121.1 - 1.1e-17 64.6 0.0 1.4e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KFX90121.1 - 1.3e-10 41.6 0.1 3.2e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MFS_1 PF07690.16 KFX90122.1 - 2.5e-22 79.3 56.8 5.1e-22 78.3 56.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LAM_C PF12544.8 KFX90123.1 - 0.00025 21.2 0.1 0.00059 20.0 0.1 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KFX90123.1 - 0.017 15.5 0.1 0.062 13.7 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily Fer4_14 PF13394.6 KFX90123.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain FAD_binding_2 PF00890.24 KFX90124.1 - 8.6e-125 417.1 3.2 1.2e-124 416.6 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFX90124.1 - 2.4e-42 143.9 0.5 4.5e-42 143.1 0.5 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term zf-GRF PF06839.12 KFX90124.1 - 3.9e-09 36.5 5.1 3.9e-09 36.5 5.1 2.7 2 0 0 2 2 2 1 GRF zinc finger Pyr_redox_2 PF07992.14 KFX90124.1 - 3e-05 23.4 1.0 0.0035 16.6 0.4 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX90124.1 - 3.2e-05 23.2 0.8 0.021 14.0 1.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KFX90124.1 - 0.00027 20.3 0.4 0.06 12.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KFX90124.1 - 0.0059 15.9 0.7 0.0098 15.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFX90124.1 - 0.18 11.4 1.8 0.59 9.7 1.8 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX90124.1 - 0.24 10.1 1.3 0.53 8.9 0.4 2.0 3 0 0 3 3 3 0 HI0933-like protein DUF3818 PF12825.7 KFX90125.1 - 5.4e-130 433.3 7.2 5.4e-130 433.3 7.2 1.7 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KFX90125.1 - 2.3e-38 131.1 1.2 5.3e-38 129.9 1.2 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KFX90125.1 - 2.3e-12 46.9 0.8 9.9e-12 44.9 0.0 2.6 3 1 0 3 3 3 1 PX domain DUF3349 PF11829.8 KFX90125.1 - 0.29 11.9 1.2 2.8 8.8 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF745 PF05335.13 KFX90125.1 - 1 9.1 4.0 23 4.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF4337 PF14235.6 KFX90125.1 - 1 9.4 4.0 0.31 11.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Myc_N PF01056.18 KFX90125.1 - 1.1 9.1 9.0 0.017 15.1 1.3 1.8 2 0 0 2 2 2 0 Myc amino-terminal region NPV_P10 PF05531.12 KFX90125.1 - 4.7 7.8 5.4 42 4.7 1.1 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 KFX90125.1 - 9.9 6.7 7.8 1.3 9.6 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cgr1 PF03879.14 KFX90126.1 - 2.4e-29 101.9 28.8 2.7e-29 101.7 28.8 1.0 1 0 0 1 1 1 1 Cgr1 family Ndufs5 PF10200.9 KFX90126.1 - 0.5 10.7 10.6 1.1 9.6 9.6 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Silic_transp PF03842.13 KFX90126.1 - 2.3 6.4 4.8 2.6 6.3 4.8 1.0 1 0 0 1 1 1 0 Silicon transporter ST7 PF04184.12 KFX90126.1 - 9.3 4.6 9.7 11 4.3 9.7 1.0 1 0 0 1 1 1 0 ST7 protein Mito_carr PF00153.27 KFX90127.1 - 7.1e-63 208.6 0.3 5.1e-21 74.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 KFX90128.1 - 1.3e-43 148.3 1.5 1.6e-43 148.0 1.5 1.1 1 0 0 1 1 1 1 TspO/MBR family Glyco_hydro_72 PF03198.14 KFX90131.1 - 7.3e-101 337.5 0.0 9.6e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase AcetDehyd-dimer PF09290.11 KFX90141.1 - 1 9.5 7.4 0.43 10.8 4.3 1.9 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Nucleo_P87 PF07267.11 KFX90141.1 - 9.8 4.9 7.7 0.24 10.2 1.7 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Metallophos PF00149.28 KFX90142.1 - 1.8e-31 110.2 0.0 5.1e-22 79.4 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX90142.1 - 0.15 12.5 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 KFX90143.1 - 2e-05 24.5 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Glyco_hydro_61 PF03443.14 KFX90144.1 - 6e-54 183.1 0.0 7.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.26 KFX90145.1 - 3e-26 91.9 1.0 3e-26 91.9 1.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX90145.1 - 1.3e-14 55.4 0.0 3e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX90145.1 - 1.8e-09 37.4 0.0 4.8e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KFX90145.1 - 0.00024 21.4 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KFX90145.1 - 0.048 13.0 0.7 0.075 12.3 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain U5_2-snRNA_bdg PF10597.9 KFX90147.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Rrn6 PF10214.9 KFX90153.1 - 8e-32 110.7 5.3 9.7e-32 110.4 5.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor EF-1_beta_acid PF10587.9 KFX90153.1 - 3.4 8.2 11.6 13 6.3 10.5 2.3 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region adh_short PF00106.25 KFX90154.1 - 1.7e-09 37.4 0.0 3.4e-09 36.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFX90154.1 - 1.5e-07 31.5 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX90154.1 - 5.8e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PD40 PF07676.12 KFX90155.1 - 2.7e-49 164.2 30.4 4.1e-08 33.0 0.3 9.8 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KFX90155.1 - 5.8e-11 41.8 8.1 0.11 11.3 3.2 7.0 4 2 2 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.11 KFX90155.1 - 0.0004 20.1 0.0 1.5 8.6 0.0 4.9 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal DUF3748 PF12566.8 KFX90155.1 - 0.0011 18.9 2.4 16 5.5 0.0 4.9 6 0 0 6 6 6 1 Protein of unknown function (DUF3748) DUF1513 PF07433.11 KFX90155.1 - 0.0084 15.2 0.1 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) Bac_rhamnosid_N PF08531.10 KFX90155.1 - 0.0089 15.9 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Pectate_lyase22 PF14583.6 KFX90155.1 - 0.032 12.9 0.5 1.1 7.8 0.0 3.6 3 2 0 3 3 3 0 Oligogalacturonate lyase adh_short PF00106.25 KFX90156.1 - 5e-12 45.7 0.0 7.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX90156.1 - 0.002 18.4 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFX90156.1 - 0.0029 17.7 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFX90156.1 - 0.0071 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFX90156.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 KR domain COesterase PF00135.28 KFX90157.1 - 1.7e-81 274.6 0.0 2.3e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX90157.1 - 1.7e-06 28.1 0.0 1.7e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX90157.1 - 0.00048 19.7 0.3 0.00096 18.7 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sec62 PF03839.16 KFX90161.1 - 3.9e-72 242.3 0.2 3.9e-72 242.3 0.2 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 HicB PF05534.12 KFX90161.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 HicB family DUF2183 PF09949.9 KFX90164.1 - 1.1e-19 70.6 0.0 1.9e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SnoaL_4 PF13577.6 KFX90165.1 - 1.5e-19 70.4 0.0 7.8e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 KFX90165.1 - 9e-05 22.8 0.1 0.00071 20.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.18 KFX90165.1 - 0.054 13.6 0.0 0.096 12.8 0.0 1.4 1 0 0 1 1 1 0 Ring hydroxylating beta subunit Egh16-like PF11327.8 KFX90169.1 - 1.1e-42 146.5 7.4 1.4e-42 146.2 7.4 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor F-box-like PF12937.7 KFX90170.1 - 4.4e-07 29.7 0.1 9.1e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF4690 PF15756.5 KFX90170.1 - 0.0011 19.5 0.8 0.0011 19.5 0.8 2.2 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 KFX90170.1 - 0.0019 18.3 0.1 0.0047 17.0 0.1 1.6 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 KFX90170.1 - 0.035 15.0 0.0 0.084 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3290 PF11694.8 KFX90170.1 - 0.052 13.5 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Adeno_E3_CR2 PF02439.15 KFX90170.1 - 0.27 11.0 3.0 0.51 10.1 3.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KFX90170.1 - 0.77 9.2 8.3 1.5 8.3 8.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NDUF_B7 PF05676.13 KFX90171.1 - 9.4e-28 95.7 5.8 1.1e-27 95.5 5.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_2 PF12796.7 KFX90172.1 - 5.4e-12 46.1 0.2 0.00033 21.2 0.8 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFX90172.1 - 1.5e-10 41.1 2.2 0.027 14.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFX90172.1 - 1.8e-09 38.0 2.2 0.0003 21.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KFX90172.1 - 9.6e-08 31.9 0.0 3.2e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.6 KFX90172.1 - 4.7e-07 29.6 0.6 0.039 14.5 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KFX90172.1 - 3.2e-06 27.3 1.1 0.11 12.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Mannitol_dh_C PF08125.13 KFX90175.1 - 9.9e-43 146.4 0.0 1.7e-42 145.6 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KFX90175.1 - 1.6e-22 80.3 0.6 6.9e-22 78.2 0.0 2.2 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KFX90175.1 - 0.083 12.5 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EC042_2821 PF18740.1 KFX90175.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase AbiEi_1 PF09407.10 KFX90175.1 - 0.16 12.3 0.1 0.4 11.0 0.1 1.7 1 1 0 1 1 1 0 AbiEi antitoxin C-terminal domain Pkinase PF00069.25 KFX90178.1 - 3.9e-54 183.8 0.0 5.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90178.1 - 6.1e-30 104.4 0.0 1.1e-28 100.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX90178.1 - 0.0092 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Cro PF09048.10 KFX90178.1 - 0.084 12.9 0.1 2.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Cro Pox_ser-thr_kin PF05445.11 KFX90178.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFX90178.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.20 KFX90179.1 - 4.9e-10 38.2 0.2 1.7e-08 33.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 KFX90179.1 - 0.01 16.2 0.6 0.18 12.3 0.0 2.5 2 0 0 2 2 2 0 Cell division protein FtsA DNA_pol_lambd_f PF10391.9 KFX90179.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda LidA_Long_CC PF18641.1 KFX90181.1 - 0.0071 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 LidA long coiled-coil domain FTO_CTD PF12934.7 KFX90181.1 - 0.0074 16.1 0.3 0.018 14.8 0.3 1.6 1 0 0 1 1 1 1 FTO C-terminal domain Spc7 PF08317.11 KFX90181.1 - 0.017 14.0 1.2 0.028 13.3 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc34 PF08657.10 KFX90181.1 - 0.039 13.8 0.2 0.057 13.2 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Fez1 PF06818.15 KFX90181.1 - 0.042 14.3 0.3 0.064 13.7 0.3 1.3 1 0 0 1 1 1 0 Fez1 Med9 PF07544.13 KFX90181.1 - 0.094 12.8 0.1 8.1 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 KFX90181.1 - 0.15 12.3 3.7 0.25 11.5 3.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KFX90181.1 - 0.27 11.3 5.1 1.2 9.2 4.3 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1488 PF07369.11 KFX90181.1 - 7.9 6.6 7.7 28 4.8 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1488) Enolase_C PF00113.22 KFX90183.1 - 3.9e-151 502.3 0.0 5.2e-151 501.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFX90183.1 - 2.2e-58 196.1 0.2 3.6e-58 195.4 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFX90183.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFX90183.1 - 0.028 13.6 0.3 4.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 KFX90184.1 - 5.8e-42 143.3 0.0 1.1e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX90184.1 - 1.9e-12 46.9 0.1 1.9e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFX90184.1 - 2.1e-10 40.2 0.1 4.6e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX90184.1 - 3.6e-06 27.5 0.0 0.00088 19.7 0.1 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KFX90184.1 - 1.2e-05 25.3 0.1 0.00018 21.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX90184.1 - 2.2e-05 24.6 0.0 5.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFX90184.1 - 2.4e-05 24.1 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFX90184.1 - 0.0011 19.2 0.1 0.018 15.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KFX90184.1 - 0.0027 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 KFX90184.1 - 0.0041 16.7 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KFX90184.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFX90184.1 - 0.0051 17.4 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KFX90184.1 - 0.0057 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 KFX90184.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KFX90184.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFX90184.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX90184.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFX90184.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AbLIM_anchor PF16182.5 KFX90184.1 - 0.037 13.9 0.3 0.037 13.9 0.3 1.6 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM AAA_14 PF13173.6 KFX90184.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFX90184.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KFX90184.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFX90184.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX90184.1 - 0.086 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KFX90184.1 - 0.098 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 KFX90184.1 - 0.098 12.4 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFX90184.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KFX90184.1 - 0.19 11.1 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein SIS PF01380.22 KFX90185.1 - 1.2e-54 183.7 0.0 2.7e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFX90185.1 - 5.7e-18 65.4 0.0 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFX90185.1 - 2e-11 43.9 0.0 4.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFX90185.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3295 PF11702.8 KFX90193.1 - 6e-177 589.9 53.2 1.5e-129 433.6 25.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KFX90193.1 - 7.8e-12 44.8 3.1 1.8e-11 43.6 3.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ribosomal_L32e PF01655.18 KFX90193.1 - 0.038 14.4 0.0 0.086 13.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L32 BAR PF03114.18 KFX90196.1 - 1.2e-49 169.1 5.7 1.5e-49 168.8 5.7 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFX90196.1 - 3.1e-05 23.2 2.5 3.8e-05 23.0 2.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 KFX90196.1 - 0.082 13.2 9.1 0.17 12.2 7.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PMEI PF04043.15 KFX90196.1 - 0.083 13.2 4.0 0.18 12.2 1.7 2.1 1 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor GBP_C PF02841.14 KFX90196.1 - 0.86 9.0 12.2 0.16 11.3 7.4 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain APG6_N PF17675.1 KFX90196.1 - 2.9 8.4 12.5 2.4 8.7 10.1 2.0 1 1 0 2 2 2 0 Apg6 coiled-coil region O-FucT PF10250.9 KFX90202.1 - 2.8e-16 60.1 0.0 1.5e-14 54.5 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PRD1_DD PF11087.8 KFX90203.1 - 0.24 11.1 1.1 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 PRD1 phage membrane DNA delivery CHAT PF12770.7 KFX90204.1 - 2.1e-32 112.7 0.0 4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 KFX90204.1 - 4.7e-19 67.6 4.6 0.02 14.7 0.1 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat DsbC_N PF10411.9 KFX90204.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus HTH_3 PF01381.22 KFX90204.1 - 0.1 12.6 0.2 8.4 6.5 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix ANAPC5 PF12862.7 KFX90204.1 - 0.21 11.7 7.0 15 5.7 0.0 5.4 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 E1-E2_ATPase PF00122.20 KFX90205.1 - 4.2e-51 173.0 0.5 1.4e-50 171.3 0.5 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KFX90205.1 - 2.9e-50 168.6 0.1 8.3e-13 48.6 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KFX90205.1 - 3.2e-39 135.4 1.7 1.9e-38 132.9 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX90205.1 - 1.7e-05 24.7 2.5 6.3e-05 22.8 1.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDCA PF18484.1 KFX90205.1 - 0.0035 17.2 0.8 20 5.0 0.0 4.0 3 1 1 4 4 4 1 Cadmium carbonic anhydrase repeat zinc_ribbon_12 PF11331.8 KFX90205.1 - 0.083 12.7 2.9 14 5.5 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF1656 PF07869.12 KFX90205.1 - 4.4 7.4 6.3 4.6 7.3 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) SSF PF00474.17 KFX90206.1 - 1.8e-21 76.5 34.3 2.7e-21 75.9 34.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zinc_ribbon_15 PF17032.5 KFX90207.1 - 9.1e-06 26.3 0.3 1.3e-05 25.8 0.3 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-piccolo PF05715.13 KFX90207.1 - 0.14 12.3 4.9 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger GrpE PF01025.19 KFX90208.1 - 0.052 13.2 1.3 0.12 12.0 1.3 1.6 1 1 0 1 1 1 0 GrpE Zmiz1_N PF18028.1 KFX90208.1 - 0.076 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain zf-C2H2 PF00096.26 KFX90209.1 - 6.4e-10 38.9 11.5 2.4e-05 24.6 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX90209.1 - 3.4e-09 36.7 12.5 5.1e-05 23.5 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX90209.1 - 9.7e-07 29.1 11.0 0.0014 19.3 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFX90209.1 - 7.3e-06 26.2 1.3 1.9e-05 24.9 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFX90209.1 - 0.00013 21.9 2.4 0.00013 21.9 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX90209.1 - 0.00061 20.0 4.2 0.00079 19.6 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFX90209.1 - 0.061 13.7 1.2 0.061 13.7 1.2 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFX90209.1 - 0.13 12.0 8.2 1.3 8.8 1.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFX90209.1 - 1 9.4 5.4 13 5.8 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Axin_b-cat_bind PF08833.10 KFX90211.1 - 0.47 10.6 11.2 0.38 10.9 1.2 4.2 3 0 0 3 3 3 0 Axin beta-catenin binding domain Sad1_UNC PF07738.13 KFX90212.1 - 1.1e-33 116.0 0.0 1.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_S64 PF08192.11 KFX90212.1 - 5.2 5.4 18.2 0.023 13.2 4.5 2.3 2 1 0 2 2 2 0 Peptidase family S64 FUN14 PF04930.15 KFX90213.1 - 1.7e-07 31.6 0.8 3.5e-07 30.5 0.8 1.5 1 0 0 1 1 1 1 FUN14 family Xpo1 PF08389.12 KFX90214.1 - 0.001 19.1 0.3 0.02 14.9 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein RRM_2 PF04059.12 KFX90215.1 - 4.8e-40 135.7 0.3 8.6e-40 134.9 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KFX90215.1 - 4.2e-05 23.3 0.0 0.077 12.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 KFX90216.1 - 4.6e-116 387.7 0.3 4.6e-116 387.7 0.3 1.9 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KFX90216.1 - 8.7e-05 22.4 5.1 8.7e-05 22.4 5.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KFX90216.1 - 0.00028 21.0 6.0 0.00028 21.0 6.0 3.4 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KFX90216.1 - 0.0036 17.5 7.1 0.01 16.0 5.4 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFX90216.1 - 0.056 13.5 4.5 0.18 11.9 1.7 3.1 2 0 0 2 2 2 0 Vps51/Vps67 Mre11_DNA_bind PF04152.14 KFX90216.1 - 0.058 13.7 0.9 0.75 10.1 0.0 2.9 3 1 0 3 3 3 0 Mre11 DNA-binding presumed domain DUF1400 PF07176.11 KFX90216.1 - 0.14 12.5 4.0 1.7 8.9 0.1 3.5 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Vps54_N PF10475.9 KFX90216.1 - 0.5 9.6 12.3 0.11 11.7 8.2 1.9 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 KFX90216.1 - 4.6 7.0 9.2 2.8 7.7 3.9 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF3510 PF12022.8 KFX90216.1 - 6.3 7.2 8.0 16 5.9 0.1 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF3510) CBFD_NFYB_HMF PF00808.23 KFX90217.1 - 2.8e-19 69.2 0.5 4.6e-19 68.5 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX90217.1 - 1e-14 55.0 0.3 1e-14 55.0 0.3 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFX90217.1 - 0.056 13.8 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 KFX90218.1 - 7.1e-37 125.7 1.0 1.6e-36 124.5 0.2 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing TGF_beta_GS PF08515.12 KFX90218.1 - 0.014 14.9 2.1 0.032 13.7 2.1 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif tRNA-synt_1b PF00579.25 KFX90219.1 - 3.7e-65 220.1 0.0 6.4e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 KFX90219.1 - 5.3e-26 90.7 0.0 1.3e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Abhydrolase_1 PF00561.20 KFX90220.1 - 6.2e-27 94.9 0.0 1.3e-20 74.2 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX90220.1 - 1.2e-12 48.9 0.0 1.4e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX90220.1 - 4.2e-11 42.6 0.0 6.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFX90220.1 - 3.9e-06 27.1 0.0 4.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KFX90220.1 - 0.00018 21.3 0.1 0.0014 18.4 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KFX90220.1 - 0.00035 19.4 0.0 0.00045 19.0 0.0 1.4 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 KFX90220.1 - 0.0012 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KFX90220.1 - 0.0022 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KFX90220.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Ser_hydrolase PF06821.13 KFX90220.1 - 0.035 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Ribosomal_S3Ae PF01015.18 KFX90221.1 - 2.3e-88 295.1 3.9 3.9e-88 294.3 3.9 1.4 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.22 KFX90221.1 - 1.6e-41 141.6 0.0 3.4e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX90221.1 - 4.3e-19 68.9 0.0 1.8e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX90221.1 - 6.8e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX90221.1 - 0.0044 16.6 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SUI1 PF01253.22 KFX90221.1 - 0.074 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor SUI1 NEMO PF11577.8 KFX90221.1 - 0.21 11.6 0.6 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO GTP_CH_N PF12471.8 KFX90222.1 - 7.4e-89 296.6 0.0 1.2e-88 296.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KFX90222.1 - 1.6e-16 60.4 0.0 2.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.13 KFX90223.1 - 1.9e-29 101.5 2.8 2.6e-29 101.1 2.8 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.6 KFX90224.1 - 1.3e-77 259.9 0.0 1.6e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFX90224.1 - 0.006 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KFX90224.1 - 0.051 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.13 KFX90225.1 - 1.1e-69 235.0 0.0 1.7e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 KFX90226.1 - 6.6e-46 155.9 1.0 7.5e-46 155.7 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX90226.1 - 1.8e-16 60.4 0.1 2.8e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX90226.1 - 2.4e-08 33.6 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX90226.1 - 6e-07 29.2 0.2 8.6e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX90226.1 - 0.00037 20.6 0.1 0.00055 20.0 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX90226.1 - 0.00061 19.7 0.9 0.056 13.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFX90226.1 - 0.0018 17.7 0.1 0.0035 16.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 KFX90226.1 - 0.017 15.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KFX90226.1 - 0.036 13.6 0.0 0.3 10.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KFX90226.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_2b PF00587.25 KFX90227.1 - 6.7e-38 130.4 0.1 1.5e-37 129.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFX90227.1 - 3.9e-20 72.1 7.5 3.9e-20 72.1 7.5 2.2 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain P5-ATPase PF12409.8 KFX90228.1 - 5e-42 142.9 1.9 5.3e-42 142.9 0.2 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFX90228.1 - 2.6e-27 95.5 0.0 5.6e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFX90228.1 - 2.6e-13 50.8 0.1 0.00011 22.6 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KFX90228.1 - 0.00032 20.5 6.0 0.00032 20.5 6.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFX90228.1 - 0.006 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) CBP_BcsF PF11120.8 KFX90228.1 - 0.15 12.2 0.2 0.45 10.7 0.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF NAP PF00956.18 KFX90229.1 - 2e-101 338.7 10.2 2e-101 338.7 10.2 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) 2-Hacid_dh_C PF02826.19 KFX90230.1 - 8.8e-52 175.0 0.0 1.3e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX90230.1 - 5.2e-30 103.8 0.1 8.4e-30 103.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX90230.1 - 0.0001 22.5 0.2 0.00094 19.4 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KFX90230.1 - 0.0017 18.4 0.3 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KFX90230.1 - 0.004 16.9 0.2 0.022 14.5 0.2 2.3 1 1 0 1 1 1 1 ACT domain XdhC_C PF13478.6 KFX90230.1 - 0.059 13.9 0.0 0.2 12.2 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain SNF2_N PF00176.23 KFX90231.1 - 8.6e-37 126.6 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX90231.1 - 3e-22 79.1 0.0 9.3e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX90231.1 - 0.00093 19.2 0.0 0.0026 17.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KFX90231.1 - 0.026 14.5 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain OTCace PF00185.24 KFX90231.1 - 0.22 11.6 0.3 0.64 10.1 0.3 1.8 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain GSH_synth_ATP PF03917.17 KFX90232.1 - 6.7e-142 472.7 0.0 7.6e-142 472.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFX90232.1 - 7.4e-35 119.5 0.0 1.3e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.25 KFX90234.1 - 3.1e-18 65.7 0.0 3.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family NigD_N PF12667.7 KFX90234.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 NigD-like N-terminal OB domain DUF4203 PF13886.6 KFX90235.1 - 5.3e-47 160.1 26.5 7.3e-47 159.7 26.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) LysM PF01476.20 KFX90236.1 - 2e-11 43.8 3.4 0.0035 17.4 0.0 4.3 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.12 KFX90236.1 - 0.0011 19.2 7.0 3 8.2 0.1 3.5 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0203) DUF1153 PF06627.11 KFX90236.1 - 0.032 14.4 0.1 17 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Glyco_hydro_108 PF05838.12 KFX90236.1 - 0.12 12.8 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase 108 DUF4358 PF14270.6 KFX90236.1 - 0.16 12.3 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PH PF00169.29 KFX90239.1 - 5.2e-05 23.7 0.0 0.00013 22.4 0.0 1.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFX90239.1 - 0.0027 18.1 0.0 0.0073 16.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Actin PF00022.19 KFX90242.1 - 2.6e-92 309.6 0.0 2e-91 306.6 0.0 1.9 1 1 0 1 1 1 1 Actin G-alpha PF00503.20 KFX90246.1 - 1.2e-123 412.8 5.9 1.4e-123 412.6 5.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFX90246.1 - 2e-15 56.7 2.4 1.1e-10 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KFX90246.1 - 4.5e-05 23.2 0.1 0.0002 21.1 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KFX90246.1 - 0.0013 18.1 5.2 0.014 14.8 0.2 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFX90246.1 - 0.0092 16.2 0.4 2.4 8.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFX90246.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KFX90246.1 - 0.056 12.5 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KFX90246.1 - 0.063 12.8 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KFX90246.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KFX90246.1 - 0.13 12.4 0.1 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Uds1 PF15456.6 KFX90250.1 - 5.2e-41 139.9 1.7 8.3e-41 139.2 1.7 1.3 1 0 0 1 1 1 1 Up-regulated During Septation HR1 PF02185.16 KFX90250.1 - 4.5e-07 29.9 1.0 9.9e-07 28.8 1.0 1.6 1 0 0 1 1 1 1 Hr1 repeat Cnn_1N PF07989.11 KFX90250.1 - 0.05 13.8 0.4 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 She9_MDM33 PF05546.11 KFX90250.1 - 0.14 12.0 0.3 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 She9 / Mdm33 family POX PF07526.11 KFX90251.1 - 4.3 7.9 8.8 1.6 9.3 0.2 2.8 2 0 0 2 2 2 0 Associated with HOX GGACT PF06094.12 KFX90252.1 - 1.2e-15 58.2 0.1 5.4e-15 56.1 0.1 1.9 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_61 PF03443.14 KFX90254.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.8 KFX90255.1 - 8.9e-39 131.8 11.1 2.4e-22 79.2 3.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) p53-inducible11 PF14936.6 KFX90255.1 - 0.095 12.8 0.3 0.39 10.8 0.3 2.0 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 UPF0029 PF01205.19 KFX90256.1 - 3.5e-34 117.3 0.0 5.3e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFX90256.1 - 2.4e-05 24.6 0.0 0.00021 21.5 0.0 2.2 1 1 0 1 1 1 1 RWD domain DUF4113 PF13438.6 KFX90256.1 - 0.16 12.1 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) MPM1 PF17234.2 KFX90257.1 - 0.0011 19.2 3.5 0.0021 18.3 3.5 1.4 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 PGA2 PF07543.12 KFX90258.1 - 3.7 7.5 6.2 7.3 6.6 6.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 AMP-binding PF00501.28 KFX90259.1 - 1.5e-17 63.3 0.0 3.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Flavodoxin_1 PF00258.25 KFX90261.1 - 1.3e-29 103.3 0.0 1.8e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KFX90261.1 - 6.1e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RNB PF00773.19 KFX90272.1 - 8.6e-52 176.5 0.0 2.7e-50 171.6 0.0 2.2 1 1 0 1 1 1 1 RNB domain ThiS PF02597.20 KFX90273.1 - 9.1e-08 32.6 0.0 3.7e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 ThiS family Zn_clus PF00172.18 KFX90273.1 - 0.00012 22.1 12.4 0.00021 21.3 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL14 PF03580.14 KFX90273.1 - 0.22 11.7 0.4 0.85 9.9 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL14-like protein DAD PF02109.16 KFX90274.1 - 6.6e-52 174.4 3.6 7.8e-52 174.2 3.6 1.1 1 0 0 1 1 1 1 DAD family Arb2 PF09757.9 KFX90274.1 - 0.0025 17.0 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Tmemb_14 PF03647.13 KFX90275.1 - 1.8e-23 83.1 9.4 2e-23 82.9 9.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KFX90275.1 - 0.12 12.6 2.1 1.7 9.0 2.1 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 Cmc1 PF08583.10 KFX90276.1 - 1.8e-18 66.3 3.0 2.1e-18 66.1 3.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.12 KFX90276.1 - 0.021 15.0 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) NADPH_Ox PF08414.10 KFX90276.1 - 0.024 15.0 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Prefoldin_2 PF01920.20 KFX90277.1 - 7.1e-26 90.2 5.8 8.4e-26 90.0 5.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 KFX90277.1 - 0.027 14.5 2.0 0.027 14.5 2.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein HBB PF06777.11 KFX90277.1 - 0.054 13.2 1.4 1.3 8.6 1.4 2.0 1 1 0 1 1 1 0 Helical and beta-bridge domain Cytochrom_B562 PF07361.11 KFX90277.1 - 0.089 13.5 1.9 0.089 13.5 1.9 1.8 2 0 0 2 2 2 0 Cytochrome b562 SLATT_1 PF18181.1 KFX90277.1 - 0.12 12.3 2.8 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Metal_resist PF13801.6 KFX90277.1 - 0.17 12.1 0.9 0.28 11.4 0.9 1.3 1 0 0 1 1 1 0 Heavy-metal resistance RRN3 PF05327.11 KFX90278.1 - 2.5e-179 597.4 0.0 2.5e-179 597.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.12 KFX90278.1 - 2.7 6.2 7.1 4.7 5.4 4.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pkinase PF00069.25 KFX90279.1 - 1e-50 172.6 0.0 1.5e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90279.1 - 2.8e-38 131.7 0.0 4.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX90279.1 - 0.0007 18.5 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFX90279.1 - 0.0028 16.7 0.0 0.055 12.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFX90279.1 - 0.0059 16.6 0.0 0.028 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX90279.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX90279.1 - 0.038 13.3 0.0 0.084 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Asp_protease_2 PF13650.6 KFX90280.1 - 3.4e-06 27.6 0.0 5.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX90280.1 - 1e-05 26.0 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KFX90280.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFX90281.1 - 2.3e-08 34.6 0.1 5.9e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX90281.1 - 1.2e-06 29.0 0.0 1.8e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KFX90281.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Pkinase PF00069.25 KFX90282.1 - 3e-71 239.9 0.0 4.1e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90282.1 - 8.3e-43 146.5 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_3 PF01494.19 KFX90282.1 - 4.7e-25 88.6 0.0 1.5e-23 83.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Kinase-like PF14531.6 KFX90282.1 - 9e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.18 KFX90282.1 - 5.1e-07 29.8 0.2 0.00033 20.8 0.0 2.8 2 0 0 2 2 2 1 POLO box duplicated region Lycopene_cycl PF05834.12 KFX90282.1 - 2.8e-06 26.6 0.5 6.8e-05 22.1 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Kdo PF06293.14 KFX90282.1 - 0.00055 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 KFX90282.1 - 0.00095 18.5 0.0 0.003 16.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX90282.1 - 0.0017 18.0 0.3 0.16 11.5 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX90282.1 - 0.0055 16.0 0.0 0.034 13.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KFX90282.1 - 0.0071 15.7 0.0 0.017 14.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KFX90282.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 KFX90282.1 - 0.013 14.3 0.1 0.028 13.1 0.1 1.5 1 1 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KFX90282.1 - 0.017 14.0 0.0 0.14 11.0 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KFX90282.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Haspin_kinase PF12330.8 KFX90282.1 - 0.021 13.7 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFX90282.1 - 0.03 13.1 0.1 0.03 13.1 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase NAD_binding_8 PF13450.6 KFX90282.1 - 0.043 14.1 0.3 0.11 12.7 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX90282.1 - 0.11 11.6 0.4 0.18 10.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain OPA3 PF07047.12 KFX90283.1 - 1.1e-40 138.3 8.4 1.1e-40 138.3 8.4 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HSP90 PF00183.18 KFX90283.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 1.5 2 0 0 2 2 2 1 Hsp90 protein DUF4795 PF16043.5 KFX90283.1 - 5.1 6.6 11.8 3.5 7.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 KFX90283.1 - 6.6 7.2 13.8 7.5 7.1 3.0 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SBDS PF01172.18 KFX90287.1 - 1.4e-26 92.4 0.6 1.6e-26 92.2 0.6 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HsdM_N PF12161.8 KFX90287.1 - 0.026 15.1 0.1 0.031 14.9 0.1 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain RhoGEF PF00621.20 KFX90288.1 - 3.8e-23 82.7 0.0 6.3e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEAD PF00270.29 KFX90289.1 - 1.8e-46 158.1 0.0 4.9e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX90289.1 - 1.4e-28 99.5 0.0 7.8e-28 97.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX90289.1 - 0.00099 19.1 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KFX90289.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.8 KFX90289.1 - 5.5 7.6 8.1 0.67 10.5 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Mitoc_mL59 PF18126.1 KFX90290.1 - 1.6e-43 148.1 4.3 2e-43 147.8 4.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Mnd1 PF03962.15 KFX90291.1 - 3.3e-22 78.5 0.1 9.5e-22 77.1 0.1 1.9 1 0 0 1 1 1 1 Mnd1 HTH domain zf-CSL PF05207.13 KFX90291.1 - 2.9e-19 68.5 0.5 7.6e-19 67.2 0.5 1.8 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KFX90291.1 - 6.5e-12 45.4 0.4 2.8e-11 43.4 0.4 2.1 1 1 0 1 1 1 1 DnaJ domain CorA PF01544.18 KFX90291.1 - 2.4 7.4 6.1 3.5 6.9 6.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Diphthami_syn_2 PF01902.17 KFX90293.1 - 3.8e-13 49.5 0.0 1.3e-06 28.1 0.0 3.1 3 0 0 3 3 3 3 Diphthamide synthase Promethin PF16015.5 KFX90302.1 - 8.7e-31 106.0 14.4 1e-30 105.8 14.4 1.0 1 0 0 1 1 1 1 Promethin MSP1a PF11670.8 KFX90302.1 - 0.025 13.9 5.8 0.026 13.8 5.8 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF1700 PF08006.11 KFX90302.1 - 1.3 8.5 6.0 1.8 8.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Med5 PF08689.10 KFX90308.1 - 6.5e-93 312.4 0.0 2.8e-92 310.3 0.0 2.0 2 1 0 2 2 2 1 Mediator complex subunit Med5 XRN_M PF17846.1 KFX90309.1 - 4e-101 339.2 5.9 6.4e-101 338.5 5.9 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFX90309.1 - 1.3e-96 322.7 0.1 2e-96 322.1 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFX90309.1 - 6.6e-76 254.4 0.0 1.3e-75 253.4 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KFX90309.1 - 1.5e-34 118.1 0.0 3.9e-34 116.7 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KFX90309.1 - 8.9e-26 89.8 0.9 1.9e-25 88.7 0.9 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KFX90309.1 - 6.2e-09 35.8 0.1 1.4e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 CAF1C_H4-bd PF12265.8 KFX90310.1 - 6.2e-28 96.9 1.3 5.6e-27 93.8 1.2 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFX90310.1 - 1.6e-27 95.2 9.3 1.8e-05 25.4 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90310.1 - 1.3e-06 28.6 1.1 0.15 12.4 0.1 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_20 PF00982.21 KFX90314.1 - 1.2e-146 489.1 0.0 2.1e-146 488.3 0.0 1.3 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFX90314.1 - 7e-75 251.1 0.0 1.6e-74 250.0 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 KFX90314.1 - 0.084 12.4 0.0 0.41 10.2 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KFX90314.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.16 KFX90315.1 - 7.1e-24 84.4 25.4 8.7e-24 84.1 25.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX90315.1 - 7.6e-05 22.2 4.1 0.00013 21.4 4.1 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 KFX90315.1 - 1.9 8.0 12.2 0.4 10.2 4.0 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1129) Rad52_Rad22 PF04098.15 KFX90318.1 - 4.8e-61 205.2 0.0 6.4e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Lin-8 PF03353.15 KFX90324.1 - 0.059 12.9 12.1 0.075 12.6 12.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mif2_N PF15624.6 KFX90324.1 - 3.7 8.3 19.9 24 5.6 0.0 2.4 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RR_TM4-6 PF06459.12 KFX90324.1 - 4.6 7.0 25.5 2 8.2 23.3 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF908 PF06012.12 KFX90324.1 - 6.2 6.1 7.9 7 5.9 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) WD40 PF00400.32 KFX90325.1 - 3e-45 151.3 24.6 2.7e-08 34.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90325.1 - 3.3e-09 36.9 0.5 0.055 13.8 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX90325.1 - 9.4e-05 21.2 4.7 0.024 13.3 0.1 4.2 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFX90325.1 - 0.0042 16.1 0.0 9.7 5.0 0.0 3.8 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX90325.1 - 0.0087 15.4 0.0 0.56 9.5 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 KFX90325.1 - 0.02 13.5 0.1 3.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KFX90325.1 - 0.022 14.7 0.9 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TAF8_C PF10406.9 KFX90326.1 - 2.9e-19 69.4 0.9 2.9e-19 69.4 0.9 2.4 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KFX90326.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mitochondr_Som1 PF11093.8 KFX90327.1 - 9.2e-27 92.9 0.0 1e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DAP3 PF10236.9 KFX90328.1 - 2.7e-48 164.8 0.0 3e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RhoGAP PF00620.27 KFX90329.1 - 3.1e-28 98.5 0.0 5.5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Lactococcin_972 PF09683.10 KFX90329.1 - 1 9.9 3.4 4.8 7.8 3.4 2.2 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) MutS_V PF00488.21 KFX90330.1 - 1.2e-72 243.9 0.1 2.2e-72 243.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX90330.1 - 1.4e-37 129.8 0.6 3.1e-37 128.7 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFX90330.1 - 4.5e-28 97.8 0.0 1.3e-27 96.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFX90330.1 - 9.9e-08 32.3 0.1 3.5e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFX90330.1 - 0.00033 21.0 0.0 0.0014 19.0 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV AIB PF15334.6 KFX90330.1 - 0.013 14.9 0.5 0.022 14.1 0.5 1.3 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein FMO-like PF00743.19 KFX90331.1 - 6e-13 48.0 0.0 1.1e-06 27.4 0.0 3.4 4 0 0 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX90331.1 - 4.8e-12 45.7 0.0 2.2e-11 43.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX90331.1 - 3e-10 39.9 0.0 0.0011 18.3 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX90331.1 - 1.8e-07 31.3 0.0 1.4e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX90331.1 - 1e-06 28.8 0.0 1.4e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX90331.1 - 6.7e-06 25.5 0.0 2.8e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFX90331.1 - 1.5e-05 25.4 0.0 5.9 7.5 0.0 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX90331.1 - 0.023 13.9 1.3 0.028 13.7 0.1 1.7 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KFX90331.1 - 0.027 14.1 0.0 8 5.9 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX90331.1 - 0.038 13.4 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX90331.1 - 0.13 10.9 0.2 0.67 8.6 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein CFEM PF05730.11 KFX90332.1 - 2.9 8.0 11.4 6 7.0 11.4 1.5 1 1 0 1 1 1 0 CFEM domain CHCH PF06747.13 KFX90334.1 - 5.1e-05 23.3 3.4 0.00011 22.2 3.3 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 KFX90334.1 - 0.0014 18.8 1.9 0.0019 18.4 1.9 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type YqzE PF14038.6 KFX90334.1 - 0.014 15.4 1.7 0.33 11.0 0.4 2.1 2 0 0 2 2 2 0 YqzE-like protein Pet191_N PF10203.9 KFX90334.1 - 0.014 15.7 3.0 0.024 14.9 3.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KFX90334.1 - 0.027 14.5 2.7 0.87 9.7 0.5 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CBM_1 PF00734.18 KFX90335.1 - 7e-14 51.5 15.0 2.8e-13 49.6 15.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Methyltransf_15 PF09445.10 KFX90336.1 - 1.4e-41 141.9 0.2 5.8e-41 139.8 0.0 2.0 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Lipase_GDSL_2 PF13472.6 KFX90336.1 - 1.8e-19 70.8 1.5 4.5e-19 69.5 1.5 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Met_10 PF02475.16 KFX90336.1 - 5.9e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Lipase_GDSL PF00657.22 KFX90336.1 - 6.6e-07 29.5 0.1 1.8e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cons_hypoth95 PF03602.15 KFX90336.1 - 1.7e-05 24.5 0.3 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFX90336.1 - 4.8e-05 23.1 0.1 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KFX90336.1 - 0.0001 22.9 0.0 0.00046 20.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.17 KFX90336.1 - 0.011 15.1 0.2 0.011 15.1 0.2 2.3 2 1 0 2 2 1 0 C-5 cytosine-specific DNA methylase Methyltransf_18 PF12847.7 KFX90336.1 - 0.034 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FliT PF05400.13 KFX90336.1 - 0.098 13.5 5.6 1.1 10.2 3.7 3.1 3 0 0 3 3 3 0 Flagellar protein FliT FAA_hydro_N_2 PF18288.1 KFX90336.1 - 0.25 11.8 1.3 1.4 9.4 0.8 2.4 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 GAPT PF11770.8 KFX90336.1 - 1.7 8.5 3.9 3 7.7 3.3 1.5 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) GRASP55_65 PF04495.14 KFX90337.1 - 3.8e-46 156.8 0.0 2.4e-44 151.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFX90337.1 - 0.0011 18.8 0.0 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Dopey_N PF04118.14 KFX90338.1 - 1.9e-118 395.1 0.0 7e-118 393.2 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Mon1 PF03164.14 KFX90339.1 - 3.3e-153 510.5 0.0 3.9e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Pkinase_fungal PF17667.1 KFX90339.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF676 PF05057.14 KFX90348.1 - 1.2e-49 168.8 0.0 1.7e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX90348.1 - 6.9e-05 22.7 0.0 0.0005 19.9 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFX90348.1 - 0.00087 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KFX90348.1 - 0.075 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KFX90348.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CMAS PF02353.20 KFX90350.1 - 2.5e-59 200.8 0.0 3.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFX90350.1 - 1.5e-12 47.7 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX90350.1 - 3.6e-10 40.3 0.0 8.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90350.1 - 5.7e-10 39.8 0.0 1.4e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX90350.1 - 0.00032 20.5 0.0 0.00081 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90350.1 - 0.0015 19.3 0.0 0.0041 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFX90350.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KFX90350.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX90350.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KFX90350.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase EF-hand_4 PF12763.7 KFX90351.1 - 3.5e-25 88.0 0.0 5.5e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KFX90351.1 - 1.4e-06 28.0 0.3 3.5e-06 26.7 0.3 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 KFX90351.1 - 0.0032 16.9 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFX90351.1 - 0.0061 17.0 0.3 6.7 7.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair E3_binding PF02817.17 KFX90351.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 e3 binding domain RAMP4 PF06624.12 KFX90353.1 - 3.5e-23 81.4 0.5 4.4e-23 81.1 0.5 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 KFX90354.1 - 4.6e-14 53.1 1.5 4.6e-14 53.1 1.5 4.3 2 1 0 2 2 2 1 Small acidic protein family CDC27 PF09507.10 KFX90354.1 - 2.7 7.3 54.3 3.8 6.8 54.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adaptin_N PF01602.20 KFX90355.1 - 1.3e-79 268.2 0.0 1.8e-79 267.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFX90355.1 - 3.7e-05 23.8 0.1 0.0005 20.1 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX90355.1 - 0.097 13.0 0.1 22 5.6 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat DUF2312 PF10073.9 KFX90355.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) HEAT_EZ PF13513.6 KFX90355.1 - 5.7 7.6 5.0 9 6.9 0.0 3.9 5 0 0 5 5 5 0 HEAT-like repeat TPR_19 PF14559.6 KFX90356.1 - 1.6e-07 31.8 1.0 0.0021 18.5 0.6 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX90356.1 - 3e-07 30.7 2.0 0.011 16.5 0.4 5.2 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90356.1 - 5.2e-06 26.2 0.8 0.0043 17.1 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX90356.1 - 8.3e-06 25.4 0.0 0.015 15.0 0.0 3.6 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KFX90356.1 - 1.7e-05 24.9 0.1 0.02 15.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90356.1 - 0.00018 21.5 0.0 0.005 16.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX90356.1 - 0.00091 19.8 6.4 0.0066 17.1 0.6 4.1 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX90356.1 - 0.011 15.8 1.8 0.016 15.4 0.2 2.1 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX90356.1 - 0.012 15.9 2.2 41 4.6 0.7 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX90356.1 - 0.013 16.1 1.3 12 6.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90356.1 - 0.058 13.2 0.0 6.2 6.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KFX90356.1 - 0.13 12.7 0.2 0.97 9.8 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat HTH_32 PF13565.6 KFX90365.1 - 0.072 13.7 0.7 0.44 11.2 0.7 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Ubiquitin_3 PF14836.6 KFX90365.1 - 0.087 12.8 1.3 0.17 11.9 1.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CBM_1 PF00734.18 KFX90366.1 - 2.8e-13 49.5 22.5 3.1e-10 39.8 4.6 3.6 4 0 0 4 4 4 2 Fungal cellulose binding domain MAR_sialic_bdg PF10564.9 KFX90366.1 - 0.47 10.5 6.1 5.8 7.0 0.2 2.8 2 2 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Amnionless PF14828.6 KFX90367.1 - 0.19 10.5 0.7 0.32 9.8 0.7 1.2 1 0 0 1 1 1 0 Amnionless HET PF06985.11 KFX90371.1 - 3.3e-24 85.9 0.0 7.4e-24 84.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.27 KFX90381.1 - 4.9e-18 64.8 0.0 7.5e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein YtxH PF12732.7 KFX90381.1 - 0.11 13.0 1.0 0.21 12.2 1.0 1.4 1 0 0 1 1 1 0 YtxH-like protein Cadherin_5 PF17892.1 KFX90399.1 - 0.19 11.7 1.5 3.8 7.6 0.1 2.8 3 1 0 3 3 3 0 Cadherin-like domain Glyoxalase PF00903.25 KFX90400.1 - 5.8e-23 81.5 0.2 5.6e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX90400.1 - 9.3e-13 48.4 0.1 6.8e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KFX90400.1 - 2.7e-07 30.9 0.1 6.9e-06 26.3 0.1 2.7 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KFX90400.1 - 2.3e-06 27.8 0.1 0.086 13.0 0.2 3.4 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4844 PF16133.5 KFX90400.1 - 0.0098 16.4 0.1 0.052 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4844) Glyoxalase_6 PF18029.1 KFX90400.1 - 0.07 13.9 0.0 3.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain FeoB_Cyto PF17910.1 KFX90401.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 FeoB cytosolic helical domain TPR_11 PF13414.6 KFX90401.1 - 0.034 13.8 1.1 0.078 12.7 0.3 1.9 2 0 0 2 2 2 0 TPR repeat RIX1 PF08167.12 KFX90401.1 - 0.036 13.8 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis TPR_17 PF13431.6 KFX90401.1 - 0.1 13.0 0.2 0.49 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SPC22 PF04573.12 KFX90404.1 - 1.9e-35 121.9 0.0 4.6e-34 117.3 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase subunit TRAPPC10 PF12584.8 KFX90406.1 - 5.9e-27 94.3 0.0 3e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Methyltransf_23 PF13489.6 KFX90406.1 - 1e-18 67.7 0.0 1.9e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90406.1 - 1.8e-09 38.2 0.0 1.1e-08 35.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX90406.1 - 2.3e-07 31.4 0.0 7.3e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX90406.1 - 1.3e-05 25.1 0.0 3.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90406.1 - 9.9e-05 23.0 0.0 0.0012 19.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Foie-gras_1 PF11817.8 KFX90406.1 - 0.00057 19.6 0.2 0.0012 18.6 0.2 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 MTS PF05175.14 KFX90406.1 - 0.0063 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KFX90406.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFX90406.1 - 0.13 11.7 0.0 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase HlyIII PF03006.20 KFX90407.1 - 1.7e-60 204.5 15.8 2.1e-60 204.2 15.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related FmiP_Thoc5 PF09766.9 KFX90408.1 - 3e-31 109.0 7.3 4.2e-31 108.6 7.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 K-box PF01486.17 KFX90408.1 - 0.064 13.4 0.3 0.064 13.4 0.3 2.9 2 1 1 3 3 3 0 K-box region APG6_N PF17675.1 KFX90408.1 - 0.12 12.9 12.6 1.5 9.4 1.7 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region IMD PF08397.11 KFX90408.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain Phage_tail_APC PF16778.5 KFX90408.1 - 0.24 11.3 2.9 0.38 10.7 0.2 2.5 2 1 1 3 3 3 0 Phage tail assembly chaperone protein Casc1_N PF15927.5 KFX90408.1 - 0.26 11.0 11.6 0.14 11.8 7.4 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Cortex-I_coil PF09304.10 KFX90408.1 - 0.3 11.3 6.2 2.3 8.5 2.2 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil RasGAP_C PF03836.15 KFX90408.1 - 5.3 7.2 8.5 0.54 10.4 1.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF3435 PF11917.8 KFX90409.1 - 1.8e-07 30.5 0.1 3.6e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MFS_1 PF07690.16 KFX90413.1 - 9.3e-22 77.4 18.9 5.6e-15 55.1 10.3 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX90413.1 - 0.1 11.1 14.3 0.023 13.3 0.8 3.5 2 2 0 3 3 3 0 MFS/sugar transport protein DUF4131 PF13567.6 KFX90413.1 - 3.7 7.2 7.3 6.7 6.3 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Fibrillarin_2 PF10113.9 KFX90414.1 - 0.0012 17.6 0.1 0.0015 17.3 0.1 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein zf-C2H2_4 PF13894.6 KFX90414.1 - 0.011 16.5 1.0 0.011 16.5 1.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX90414.1 - 0.03 14.8 0.8 0.086 13.3 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFX90414.1 - 0.043 14.1 0.6 0.079 13.3 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TPR_12 PF13424.6 KFX90415.1 - 1.4e-26 92.5 6.0 9.1e-10 38.7 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFX90415.1 - 1e-12 47.4 5.1 0.00018 21.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90415.1 - 7.5e-07 28.7 2.0 1.6 8.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90415.1 - 0.00023 21.0 6.3 0.2 11.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90415.1 - 0.00023 21.1 2.0 2.2 8.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90415.1 - 0.0005 20.0 7.1 13 6.2 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90415.1 - 0.02 15.1 1.4 0.057 13.6 0.3 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Mating_C PF12737.7 KFX90415.1 - 0.13 11.4 2.4 0.23 10.6 1.7 1.7 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 Beta-lactamase PF00144.24 KFX90416.1 - 9.1e-46 156.6 0.0 1.1e-45 156.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX90416.1 - 0.0037 16.7 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF202 PF02656.15 KFX90423.1 - 6.9e-22 77.7 1.3 6.9e-22 77.7 1.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SH3_1 PF00018.28 KFX90423.1 - 8e-12 44.6 0.6 1.3e-10 40.7 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFX90423.1 - 2.1e-09 37.1 0.1 4.6e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX90423.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 KFX90423.1 - 0.044 14.5 17.9 0.7 10.5 5.8 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TM140 PF14985.6 KFX90423.1 - 0.15 11.6 0.3 0.24 10.9 0.3 1.2 1 0 0 1 1 1 0 TM140 protein family Gemini_mov PF01708.16 KFX90423.1 - 2.5 7.9 3.7 6.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein Pkinase PF00069.25 KFX90428.1 - 2.7e-50 171.2 0.1 8.2e-50 169.6 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90428.1 - 4.5e-23 81.9 0.1 9.9e-23 80.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX90428.1 - 0.00042 20.3 0.1 0.00042 20.3 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX90428.1 - 0.0034 17.0 0.2 0.0096 15.5 0.2 1.6 1 1 0 1 1 1 1 RIO1 family SNF2_N PF00176.23 KFX90429.1 - 1.8e-65 221.0 0.0 3.6e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX90429.1 - 2.5e-20 72.9 0.0 7e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFX90429.1 - 2.4e-08 33.5 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFX90429.1 - 7e-07 29.4 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UCH PF00443.29 KFX90433.1 - 8.3e-13 48.4 0.0 8.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KFX90433.1 - 5.2e-10 39.0 0.0 8.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.6 KFX90433.1 - 2e-07 30.9 0.0 2.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KFX90433.1 - 0.0057 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain HOIP-UBA PF16678.5 KFX90433.1 - 0.044 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Glyco_hydro_4 PF02056.16 KFX90436.1 - 0.031 13.8 0.5 0.042 13.4 0.5 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase TP_methylase PF00590.20 KFX90438.1 - 5e-44 150.8 0.6 4.9e-43 147.6 0.6 2.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 KFX90438.1 - 1e-11 44.0 0.1 5.1e-11 41.8 0.2 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KFX90438.1 - 1.2e-10 40.8 0.1 3.4e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KFX90438.1 - 2.8e-10 40.6 0.0 5.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding WSC PF01822.19 KFX90439.1 - 2.4e-14 53.3 5.9 5.9e-14 52.0 5.9 1.7 1 0 0 1 1 1 1 WSC domain eIF-5_eIF-2B PF01873.17 KFX90442.1 - 6.3e-39 132.5 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KFX90442.1 - 4e-23 81.4 0.0 1.4e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Ku_C PF03730.14 KFX90442.1 - 0.16 12.7 0.4 0.16 12.7 0.4 3.0 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm HEAT_2 PF13646.6 KFX90443.1 - 2.4e-05 24.6 0.7 16 6.0 0.0 5.2 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KFX90443.1 - 0.0011 19.1 0.4 3.1 8.3 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat SRPRB PF09439.10 KFX90444.1 - 1.4e-32 112.6 0.0 1e-31 109.8 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFX90444.1 - 4e-07 29.6 0.0 1.3e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX90444.1 - 5.4e-06 26.1 0.0 1.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX90444.1 - 3e-05 24.1 0.0 6.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFX90444.1 - 4.5e-05 23.0 0.0 0.0013 18.3 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KFX90444.1 - 0.00023 21.6 0.7 0.00057 20.3 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KFX90444.1 - 0.0037 16.9 0.3 0.89 9.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFX90444.1 - 0.0052 16.7 1.3 1.3 8.9 0.2 2.9 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFX90444.1 - 0.0099 16.2 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFX90444.1 - 0.023 14.3 0.0 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KFX90444.1 - 0.024 14.8 0.1 0.098 12.9 0.1 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFX90444.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KFX90444.1 - 0.041 13.1 0.0 2.7 7.0 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 KFX90444.1 - 0.041 13.9 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KFX90444.1 - 0.043 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 KFX90444.1 - 0.046 14.2 0.0 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KFX90444.1 - 0.067 13.6 1.2 0.65 10.4 1.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KFX90444.1 - 0.091 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFX90444.1 - 0.091 12.3 0.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFX90444.1 - 0.1 12.3 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFX90444.1 - 0.12 11.9 0.1 5.4 6.6 0.0 2.4 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 KFX90444.1 - 0.13 12.1 0.1 5.4 6.7 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KFX90444.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 KFX90444.1 - 0.25 11.1 0.9 2.4 7.9 0.2 2.4 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DHHC PF01529.20 KFX90445.1 - 4.8e-35 120.6 8.7 4.8e-35 120.6 8.7 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KFX90445.1 - 7.4e-32 109.8 0.5 1.1e-11 45.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX90445.1 - 2.2e-21 75.9 1.2 5.2e-05 23.7 0.3 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX90445.1 - 2e-19 69.4 0.8 3.4e-05 24.0 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX90445.1 - 2.1e-19 67.6 3.3 2.7e-07 30.4 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFX90445.1 - 6.3e-17 61.2 2.4 2.2e-05 24.7 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat PocR PF10114.9 KFX90445.1 - 0.4 10.4 2.1 0.78 9.5 2.1 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR Kinesin PF00225.23 KFX90446.1 - 4.2e-109 364.5 1.1 6.1e-109 364.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KFX90446.1 - 1.7e-43 149.0 0.2 1.3e-42 146.0 0.0 2.5 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KFX90446.1 - 1.7e-34 119.5 17.2 9.8e-31 107.3 0.4 4.2 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KFX90446.1 - 3.5e-23 82.2 0.0 1e-22 80.7 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KFX90446.1 - 9e-06 26.1 0.0 3.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 KFX90446.1 - 1.3e-05 25.5 0.3 4.5e-05 23.8 0.3 2.0 1 0 0 1 1 1 1 Kinesin protein 1B PDDEXK_1 PF12705.7 KFX90446.1 - 0.02 14.8 2.1 0.11 12.4 2.1 2.3 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily AAA_22 PF13401.6 KFX90446.1 - 0.065 13.5 0.4 0.64 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4709 PF15821.5 KFX90446.1 - 3.1 8.1 11.0 9.2 6.6 5.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) PALP PF00291.25 KFX90447.1 - 4.5e-66 223.3 0.2 5.8e-66 222.9 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFX90447.1 - 4.1e-12 46.4 0.0 1.5e-08 34.9 0.0 3.4 4 0 0 4 4 4 2 CBS domain Peptidase_M24 PF00557.24 KFX90448.1 - 1.1e-53 182.1 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFX90448.1 - 1.1e-23 83.3 0.0 3e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tup_N PF08581.10 KFX90448.1 - 0.087 13.1 1.2 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 Tup N-terminal HsbA PF12296.8 KFX90448.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Ribul_P_3_epim PF00834.19 KFX90453.1 - 1.9e-50 171.0 0.1 1.8e-49 167.8 0.1 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KFX90453.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CBM_14 PF01607.24 KFX90454.1 - 3.4e-36 123.2 58.4 7.8e-09 35.6 8.5 6.8 5 1 2 7 7 7 6 Chitin binding Peritrophin-A domain RANK_CRD_2 PF18278.1 KFX90454.1 - 0.24 11.6 6.2 9.3 6.5 0.1 4.1 4 0 0 4 4 4 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Pkinase PF00069.25 KFX90455.1 - 6.6e-23 81.4 0.0 7.4e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90455.1 - 4.4e-20 72.0 0.0 7.1e-20 71.4 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX90455.1 - 1.3e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TrkH PF02386.16 KFX90456.1 - 1.5e-102 343.7 3.5 2.7e-98 329.6 0.5 2.1 2 0 0 2 2 2 2 Cation transport protein HA2 PF04408.23 KFX90461.1 - 1.6e-15 57.3 1.8 4e-15 56.0 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX90461.1 - 3.5e-15 56.3 0.9 2e-14 53.9 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX90461.1 - 4.8e-13 49.3 0.0 9.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 KFX90461.1 - 9.7e-12 45.2 0.0 2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 KFX90461.1 - 4.8e-10 39.5 0.2 1.1e-09 38.3 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX90461.1 - 0.00068 19.7 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX90461.1 - 0.0024 18.1 2.2 0.011 16.0 2.2 2.0 1 1 0 1 1 1 1 AAA domain dsRBD2 PF17842.1 KFX90461.1 - 0.0025 18.0 0.1 0.0056 16.9 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 IHABP4_N PF16174.5 KFX90461.1 - 0.0044 17.6 0.3 0.0044 17.6 0.3 1.9 2 0 0 2 2 1 1 Intracellular hyaluronan-binding protein 4 N-terminal AAA_23 PF13476.6 KFX90461.1 - 0.013 16.0 0.0 0.07 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DND1_DSRM PF14709.7 KFX90461.1 - 0.014 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.6 KFX90461.1 - 0.026 14.3 0.2 0.099 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFX90461.1 - 0.026 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KFX90461.1 - 0.03 13.7 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 KFX90461.1 - 0.031 14.0 0.1 0.66 9.7 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2533 PF10752.9 KFX90461.1 - 0.1 13.1 0.6 0.31 11.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) PQ-loop PF04193.14 KFX90463.1 - 6.1e-28 96.4 17.8 1.3e-14 53.7 1.9 2.8 3 0 0 3 3 3 2 PQ loop repeat Dynamin_N PF00350.23 KFX90464.1 - 1.3e-42 145.7 0.0 2.9e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX90464.1 - 6.3e-14 51.9 0.0 7.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KFX90464.1 - 7.4e-06 26.0 0.2 0.00016 21.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX90464.1 - 0.049 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX90464.1 - 0.098 12.3 0.4 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KFX90464.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain Apolipoprotein PF01442.18 KFX90464.1 - 0.68 9.8 5.0 0.43 10.4 0.1 2.6 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain GATase_4 PF13230.6 KFX90465.1 - 3.3e-13 49.2 0.0 2.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KFX90465.1 - 6.7e-08 32.8 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Cation_efflux PF01545.21 KFX90466.1 - 1.1e-12 48.2 16.4 1.4e-12 47.8 16.4 1.1 1 0 0 1 1 1 1 Cation efflux family PNRC PF15365.6 KFX90466.1 - 8.1 6.4 11.7 4.5 7.2 1.4 3.9 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator motif PIG-Y PF15159.6 KFX90467.1 - 4e-23 82.1 8.2 6e-23 81.5 8.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KFX90467.1 - 0.041 14.4 3.1 0.85 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 KFX90467.1 - 3.8 7.7 5.4 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Ebp2 PF05890.12 KFX90469.1 - 4e-96 321.7 19.8 4e-96 321.7 19.8 2.0 2 0 0 2 2 2 2 Eukaryotic rRNA processing protein EBP2 zf-rbx1 PF12678.7 KFX90471.1 - 1.6e-10 41.1 0.7 2.8e-10 40.3 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX90471.1 - 2.2e-08 34.3 5.0 5.8e-08 32.9 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX90471.1 - 1.5e-06 27.9 5.0 7.3e-06 25.7 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX90471.1 - 2.8e-06 27.1 0.8 4.8e-06 26.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX90471.1 - 1.5e-05 24.9 1.3 3.3e-05 23.8 1.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX90471.1 - 6.3e-05 22.7 0.3 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFX90471.1 - 0.00019 21.4 1.4 0.0018 18.3 0.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFX90471.1 - 0.00099 18.8 7.3 0.017 14.8 0.3 3.1 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFX90471.1 - 0.0014 18.4 1.2 0.0014 18.4 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX90471.1 - 0.0043 16.7 1.0 0.011 15.4 1.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2921 PF11145.8 KFX90471.1 - 0.012 13.4 0.3 0.018 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 KFX90471.1 - 0.018 15.0 1.1 0.047 13.7 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFX90471.1 - 0.57 10.4 2.9 2.3 8.4 2.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 KFX90471.1 - 1.1 9.5 2.4 33 4.7 0.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 HSBP1 PF06825.12 KFX90472.1 - 2.4e-13 49.7 2.4 3.7e-13 49.1 2.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 KFX90472.1 - 0.024 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2379 PF09543.10 KFX90472.1 - 0.07 13.3 0.1 0.082 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) CHDCT2 PF08074.11 KFX90472.1 - 0.096 12.9 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Thioredoxin PF00085.20 KFX90473.1 - 6.5e-56 186.7 0.0 3.6e-28 97.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KFX90473.1 - 8.9e-24 84.2 3.9 1.9e-23 83.2 3.9 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KFX90473.1 - 3.5e-16 59.6 0.1 3.5e-09 37.1 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFX90473.1 - 8e-14 51.7 0.0 3.3e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFX90473.1 - 1.1e-12 48.0 0.0 5.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFX90473.1 - 3.5e-10 40.1 0.1 0.0059 16.9 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFX90473.1 - 3.7e-08 33.3 0.2 0.008 16.1 0.0 2.5 1 1 1 2 2 2 2 AhpC/TSA family TraF PF13728.6 KFX90473.1 - 6.2e-07 29.5 0.0 0.00047 20.0 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KFX90473.1 - 5.5e-06 26.2 2.3 0.087 12.5 0.1 2.9 2 1 1 3 3 3 2 Redoxin HyaE PF07449.11 KFX90473.1 - 1.4e-05 25.0 0.0 0.0065 16.4 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KFX90473.1 - 0.0015 18.7 0.1 1.9 8.7 0.0 3.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.6 KFX90473.1 - 0.0017 18.1 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 KFX90473.1 - 0.003 17.5 0.0 1.7 8.7 0.0 3.2 4 0 0 4 4 4 1 Thioredoxin domain Helicase_C_4 PF13871.6 KFX90473.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue DDE_Tnp_1_2 PF13586.6 KFX90473.1 - 0.057 13.8 0.0 0.93 9.9 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain DUF953 PF06110.11 KFX90473.1 - 0.12 12.0 1.4 0.61 9.7 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) Gp-FAR-1 PF05823.12 KFX90473.1 - 0.7 10.2 8.3 1.3 9.3 8.3 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DSBA PF01323.20 KFX90473.1 - 0.84 9.4 5.7 7.7 6.2 0.1 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain MKT1_C PF12246.8 KFX90474.1 - 3.6e-67 226.1 0.0 6.4e-67 225.3 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KFX90474.1 - 6.1e-31 106.6 0.1 1.9e-30 105.0 0.1 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KFX90474.1 - 0.12 12.9 0.0 0.59 10.6 0.0 2.3 1 0 0 1 1 1 0 XPG N-terminal domain DUF1882 PF08966.11 KFX90475.1 - 0.045 14.0 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) Pfg27 PF09216.10 KFX90475.1 - 0.073 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Pfg27 TruB_N PF01509.18 KFX90476.1 - 8.2e-48 162.6 0.5 2e-47 161.3 0.5 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFX90476.1 - 1.4e-08 34.8 0.0 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Sec2p PF06428.11 KFX90477.1 - 1.1e-10 41.4 6.5 1.1e-10 41.4 6.5 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p LMBR1 PF04791.16 KFX90477.1 - 0.0097 14.9 0.6 0.011 14.7 0.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein V_ATPase_I PF01496.19 KFX90477.1 - 0.022 12.7 1.8 0.026 12.5 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zinc_ribbon_9 PF14369.6 KFX90477.1 - 0.095 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon Jnk-SapK_ap_N PF09744.9 KFX90477.1 - 0.11 12.7 12.3 2.1 8.6 6.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 KFX90477.1 - 0.14 12.2 7.8 0.66 10.1 0.4 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CsbD PF05532.12 KFX90477.1 - 0.19 11.6 0.8 0.55 10.2 0.8 1.7 1 0 0 1 1 1 0 CsbD-like DUF4795 PF16043.5 KFX90477.1 - 0.2 11.2 8.2 0.67 9.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 KFX90477.1 - 0.54 10.9 18.9 3.9 8.2 5.9 3.6 2 2 0 2 2 2 0 SlyX DUF4407 PF14362.6 KFX90477.1 - 1.2 8.5 12.5 2.1 7.6 12.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KFX90477.1 - 4.6 4.6 14.4 16 2.8 14.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) COG2 PF06148.11 KFX90477.1 - 5.4 7.1 7.9 8.3 6.5 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YlqD PF11068.8 KFX90477.1 - 5.6 7.3 11.7 3.8 7.9 4.0 2.1 2 0 0 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KFX90477.1 - 6.7 6.2 12.4 49 3.4 12.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit GCN5L1 PF06320.13 KFX90477.1 - 7 6.8 10.0 0.8 9.9 3.2 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) HR1 PF02185.16 KFX90477.1 - 9.1 6.5 13.7 0.16 12.1 2.3 3.0 3 1 1 4 4 3 0 Hr1 repeat DnaJ_C PF01556.18 KFX90478.1 - 1.2e-38 132.6 0.4 2.7e-38 131.4 0.4 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain Ribosomal_L32e PF01655.18 KFX90478.1 - 2e-30 105.4 0.1 4.4e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.31 KFX90478.1 - 1.1e-21 76.7 3.2 2.2e-21 75.7 3.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX90478.1 - 7.1e-14 51.9 18.7 1.4e-13 51.0 18.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFX90478.1 - 0.077 13.0 13.2 0.73 9.8 1.1 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFX90478.1 - 0.089 12.8 7.5 2.8 8.0 0.6 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KFX90478.1 - 0.22 11.7 6.3 1.3 9.2 0.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1356 PF07092.12 KFX90478.1 - 6.3 6.0 7.4 9.1 5.5 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 KFX90478.1 - 9.1 5.9 9.4 52 3.4 1.4 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 tRNA-synt_1c PF00749.21 KFX90479.1 - 3e-86 289.2 0.0 4e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain JAB PF01398.21 KFX90480.1 - 2.5e-31 108.1 0.2 1.1e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFX90480.1 - 6.6e-21 75.0 1.0 1e-20 74.4 0.3 1.8 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFX90480.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFX90480.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) MAP65_ASE1 PF03999.12 KFX90481.1 - 1.1e-82 278.7 7.2 1.5e-82 278.3 7.2 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4073 PF13285.6 KFX90481.1 - 0.068 12.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) TipAS PF07739.13 KFX90481.1 - 0.33 11.5 2.5 1.6 9.3 0.2 3.1 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain DUF1664 PF07889.12 KFX90481.1 - 1.9 8.6 4.0 24 5.0 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFX90481.1 - 3 8.2 11.4 8.5 6.8 4.7 4.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_4 PF12763.7 KFX90482.1 - 0.00095 19.1 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFX90482.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 EF hand DNA_ligase_A_M PF01068.21 KFX90484.1 - 1.7e-45 155.2 0.0 3.2e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFX90484.1 - 6.5e-42 143.8 0.0 1.3e-41 142.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KFX90484.1 - 8.8e-17 61.9 0.0 1.9e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KFX90484.1 - 5.9e-15 55.7 0.0 1.8e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KFX90484.1 - 2.7e-14 53.3 0.0 2.7e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFX90484.1 - 1.1e-07 32.0 0.5 0.00025 21.3 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 KFX90484.1 - 3e-06 27.5 0.1 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KFX90484.1 - 0.0001 22.3 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV UPRTase PF14681.6 KFX90485.1 - 2.4e-71 239.5 0.0 2.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFX90485.1 - 5.6e-05 22.7 0.1 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KFX90485.1 - 0.0004 20.5 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.17 KFX90485.1 - 0.051 12.9 0.4 0.87 8.9 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase P5CR_dimer PF14748.6 KFX90485.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF2491 PF10679.9 KFX90487.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Abhydrolase_6 PF12697.7 KFX90488.1 - 0.0079 16.8 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 KFX90488.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KFX90488.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KFX90488.1 - 0.24 10.9 0.0 0.46 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MRG PF05712.13 KFX90492.1 - 1.7e-54 184.2 0.0 2.5e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFX90492.1 - 2.5e-08 33.6 1.4 5.7e-08 32.5 1.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFX90492.1 - 0.015 15.2 1.2 0.042 13.8 1.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain eIF-6 PF01912.18 KFX90501.1 - 4e-80 267.8 0.9 6.2e-80 267.2 0.9 1.3 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 KFX90501.1 - 0.042 13.3 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Swi5 PF07061.11 KFX90502.1 - 2.5e-28 98.0 2.6 8e-28 96.4 2.5 1.8 1 1 0 1 1 1 1 Swi5 DUF2203 PF09969.9 KFX90502.1 - 0.004 17.9 4.2 0.072 13.8 4.2 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) DUF812 PF05667.11 KFX90502.1 - 0.0072 15.3 3.2 0.008 15.1 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GBR_NSP5 PF17580.2 KFX90502.1 - 0.024 14.5 0.8 0.032 14.0 0.8 1.1 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 ASD2 PF08687.11 KFX90502.1 - 0.027 14.0 3.9 0.032 13.8 3.9 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 GAS PF13851.6 KFX90502.1 - 0.044 13.1 7.9 0.064 12.6 7.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 KFX90502.1 - 0.063 13.4 10.3 0.09 12.9 9.8 1.4 1 1 0 1 1 1 0 Tropomyosin like Hamartin PF04388.12 KFX90502.1 - 0.12 11.0 8.6 0.14 10.8 8.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4570 PF15134.6 KFX90502.1 - 0.12 12.4 3.8 0.19 11.7 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) YdfA_immunity PF12127.8 KFX90502.1 - 0.2 10.7 5.1 0.24 10.4 5.1 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial WDCP PF15390.6 KFX90502.1 - 0.24 9.8 1.8 0.28 9.5 1.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Med30 PF11315.8 KFX90502.1 - 1.1 9.5 5.7 1.5 9.0 5.1 1.6 1 1 1 2 2 2 0 Mediator complex subunit 30 RR_TM4-6 PF06459.12 KFX90502.1 - 1.2 8.9 8.0 1.4 8.7 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2681 PF10883.8 KFX90502.1 - 2.1 8.8 8.2 3.2 8.2 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Presenilin PF01080.17 KFX90502.1 - 2.4 6.8 4.2 2.5 6.8 4.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 KFX90502.1 - 3.8 7.6 6.9 5.2 7.2 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) adh_short PF00106.25 KFX90503.1 - 1.1e-08 34.7 0.2 2.3e-08 33.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90503.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SurE PF01975.17 KFX90504.1 - 6.7e-50 169.6 0.0 1e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 KFX90504.1 - 7.5e-25 87.6 0.0 1.2e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DASH_Duo1 PF08651.10 KFX90506.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 Aldolase_II PF00596.21 KFX90527.1 - 2.8e-44 151.3 0.0 4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MelC1 PF06236.11 KFX90527.1 - 0.29 11.2 1.7 0.9 9.6 0.1 2.4 3 0 0 3 3 3 0 Tyrosinase co-factor MelC1 Hemerythrin PF01814.23 KFX90528.1 - 3.6e-09 37.3 0.7 1.3e-08 35.5 0.7 1.9 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Transglut_core PF01841.19 KFX90529.1 - 2.7e-11 43.9 0.0 5.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KFX90529.1 - 0.00078 19.0 0.0 0.018 14.6 0.0 2.6 2 1 1 3 3 3 1 Transglutaminase-like domain 2-Hacid_dh_C PF02826.19 KFX90535.1 - 2.1e-51 173.8 0.0 3.2e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX90535.1 - 6.2e-16 58.3 0.0 8.5e-16 57.8 0.0 1.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain EF-hand_1 PF00036.32 KFX90541.1 - 3.1e-25 85.8 5.1 8e-06 25.0 0.1 5.5 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 KFX90541.1 - 1.2e-22 77.8 6.0 6.7e-05 22.5 0.1 5.4 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 KFX90541.1 - 1.7e-19 70.0 2.9 5.4e-08 33.2 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 KFX90541.1 - 1.7e-16 59.8 7.1 2.9e-05 23.8 0.0 5.2 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KFX90541.1 - 5.8e-16 57.2 14.6 4.7e-05 22.7 0.2 5.7 6 0 0 6 6 6 4 EF hand EF-hand_10 PF14788.6 KFX90541.1 - 0.16 11.9 0.1 27 4.7 0.0 3.3 3 1 1 4 4 4 0 EF hand DUF4149 PF13664.6 KFX90546.1 - 0.082 13.2 0.7 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Ferric_reduct PF01794.19 KFX90546.1 - 1.5 8.9 6.7 1.6 8.8 1.2 2.5 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Cmc1 PF08583.10 KFX90554.1 - 3.2e-12 46.3 4.5 8.5e-12 44.9 4.5 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Utp11 PF03998.13 KFX90555.1 - 7.9e-61 206.1 22.8 9e-61 205.9 22.8 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KFX90555.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Mt_ATP-synt_D PF05873.12 KFX90555.1 - 1.2 9.0 7.4 0.26 11.2 3.9 1.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) KxDL PF10241.9 KFX90555.1 - 2.7 8.3 7.9 19 5.6 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein RPN2_C PF18004.1 KFX90555.1 - 6.5 6.7 13.1 0.21 11.5 6.8 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TMEM119 PF15724.5 KFX90555.1 - 8 6.4 6.4 13 5.8 6.4 1.2 1 0 0 1 1 1 0 TMEM119 family Nucleoside_tran PF01733.18 KFX90556.1 - 0.068 12.5 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter Wzy_C_2 PF11846.8 KFX90556.1 - 0.11 12.4 0.1 1 9.2 0.0 2.0 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal zf-HC5HC2H PF13771.6 KFX90560.1 - 0.0025 18.0 2.9 0.004 17.4 2.9 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFX90560.1 - 0.024 14.8 3.1 0.036 14.2 3.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Pput2613-deam PF14427.6 KFX90560.1 - 0.067 13.1 1.6 0.099 12.5 0.1 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase DUF35_N PF12172.8 KFX90560.1 - 0.21 11.5 2.3 7.7 6.5 0.2 2.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PHD PF00628.29 KFX90560.1 - 0.93 9.4 4.8 1.8 8.5 4.8 1.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KFX90560.1 - 1 9.7 7.4 0.25 11.7 2.6 2.0 2 0 0 2 2 2 0 RING-like domain DEAD PF00270.29 KFX90561.1 - 4.3e-42 143.9 0.1 7.4e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX90561.1 - 1.8e-33 115.2 0.0 6.6e-33 113.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFX90561.1 - 0.00048 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX90561.1 - 0.0013 19.1 0.0 0.012 15.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFX90561.1 - 0.0016 18.5 0.0 0.0031 17.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KFX90561.1 - 0.068 13.1 0.2 0.24 11.3 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFX90561.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 KFX90561.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KFX90561.1 - 0.24 11.7 0.8 1 9.6 0.8 2.0 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 KFX90571.1 - 4.5e-17 62.2 0.0 7.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX90571.1 - 2.1e-16 59.8 3.1 3.5e-16 59.0 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX90571.1 - 6.5e-07 30.5 0.0 1.2e-06 29.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX90571.1 - 0.0017 17.7 0.2 0.0029 16.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFX90571.1 - 0.0061 15.9 0.3 0.0099 15.3 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ERAP1_C PF11838.8 KFX90572.1 - 4.4e-87 292.6 1.6 8.3e-86 288.4 0.7 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFX90572.1 - 1.5e-82 276.4 2.5 2.4e-82 275.7 2.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFX90572.1 - 1e-44 153.0 1.3 1.8e-43 148.9 0.3 2.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain MATalpha_HMGbox PF04769.12 KFX90572.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box CENP-W PF15510.6 KFX90573.1 - 7.1e-05 23.0 0.1 8.1e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 KFX90573.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C14 PF00656.22 KFX90574.1 - 0.11 12.4 3.4 0.082 12.8 1.2 1.9 1 1 1 2 2 2 0 Caspase domain DUF4404 PF14357.6 KFX90574.1 - 0.63 10.7 5.3 2 9.1 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TMCO5 PF14992.6 KFX90574.1 - 0.72 9.4 8.3 1.2 8.6 8.3 1.3 1 0 0 1 1 1 0 TMCO5 family DUF2975 PF11188.8 KFX90578.1 - 0.0013 18.6 1.7 0.0024 17.7 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) LRR_8 PF13855.6 KFX90579.1 - 1.1e-24 85.9 32.8 7.3e-07 28.9 3.4 7.1 5 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KFX90579.1 - 3.9e-24 84.3 36.3 0.00015 22.0 4.0 8.2 6 1 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFX90579.1 - 1e-08 34.9 14.2 0.0001 21.9 0.7 4.5 1 1 4 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 KFX90579.1 - 0.015 15.8 32.3 4 8.3 0.4 10.6 10 3 0 10 10 10 0 Leucine Rich Repeat Tubulin PF00091.25 KFX90580.1 - 4.9e-65 219.4 0.0 6.6e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX90580.1 - 1.9e-46 157.3 0.0 3e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFX90580.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tim17 PF02466.19 KFX90581.1 - 1.2e-11 45.0 2.2 1.8e-11 44.4 2.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KFX90581.1 - 0.0023 18.0 2.0 0.15 12.3 0.8 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5518) EpuA PF11772.8 KFX90581.1 - 0.039 13.6 0.4 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Brix PF04427.18 KFX90582.1 - 2.1e-43 148.7 0.1 2.9e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sugar_tr PF00083.24 KFX90584.1 - 3.2e-81 273.5 26.6 3.9e-81 273.2 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90584.1 - 1.2e-30 106.7 27.0 1.4e-26 93.3 19.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX90584.1 - 3.9e-06 25.7 4.9 3.9e-06 25.7 4.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KFX90584.1 - 5.1e-05 21.9 2.4 9e-05 21.1 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFX90584.1 - 0.0033 16.8 12.0 0.022 14.1 7.6 2.9 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TPR_14 PF13428.6 KFX90591.1 - 9e-32 107.0 22.7 0.00016 22.2 0.1 12.4 4 3 9 13 13 12 9 Tetratricopeptide repeat TPR_19 PF14559.6 KFX90591.1 - 9.1e-27 93.4 14.4 7.7e-08 32.7 0.2 9.8 5 3 5 10 10 10 7 Tetratricopeptide repeat PRP1_N PF06424.12 KFX90591.1 - 6e-13 49.4 0.0 1.5e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_16 PF13432.6 KFX90591.1 - 1.2e-12 48.3 12.0 0.00027 21.5 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90591.1 - 2e-12 46.2 10.9 0.21 11.8 0.0 9.7 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90591.1 - 1.5e-10 40.4 0.0 0.6 10.5 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX90591.1 - 2.9e-09 36.7 2.2 25 5.5 0.2 9.3 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90591.1 - 2.3e-07 30.3 0.0 0.57 10.1 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX90591.1 - 2.8e-07 30.1 19.0 8.1e-05 22.0 4.7 5.9 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFX90591.1 - 3.8e-07 30.0 5.0 0.0064 16.2 0.8 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KFX90591.1 - 9.2e-07 29.1 3.4 22 5.9 0.0 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 KFX90591.1 - 5.1e-06 25.7 1.9 0.015 14.2 0.0 4.4 3 1 3 6 6 6 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 KFX90591.1 - 1.1e-05 25.0 5.2 2.5 7.8 0.0 6.2 5 1 1 6 6 6 1 TPR repeat TPR_9 PF13371.6 KFX90591.1 - 1.9e-05 24.7 8.1 0.29 11.3 0.1 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 KFX90591.1 - 0.00036 20.6 0.4 3.8 7.4 0.0 4.1 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KFX90591.1 - 0.00076 19.7 3.6 1.5 9.2 0.0 6.0 5 2 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 KFX90591.1 - 0.0009 18.1 0.4 1.8 7.2 0.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 KFX90591.1 - 0.0073 16.5 0.2 4.8 7.5 0.0 4.2 3 1 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 KFX90591.1 - 0.0094 15.9 3.0 4.1 7.3 0.1 3.9 2 1 2 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal ZNRF_3_ecto PF18212.1 KFX90591.1 - 0.042 13.8 0.3 48 4.0 0.0 4.1 4 0 0 4 4 4 0 ZNRF-3 Ectodomain DUF4396 PF14342.6 KFX90592.1 - 1.9e-34 119.0 1.7 2.1e-34 118.9 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Zincin_1 PF06262.11 KFX90593.1 - 0.12 12.5 0.1 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Zincin-like metallopeptidase DUF521 PF04412.13 KFX90594.1 - 0.066 11.9 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) ArAE_2_N PF10337.9 KFX90595.1 - 7.2e-47 160.5 10.2 1e-38 133.6 0.4 4.0 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KFX90595.1 - 1.4e-17 64.0 19.0 1.4e-17 64.0 19.0 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFX90595.1 - 7.6e-06 25.9 0.0 0.00084 19.2 0.1 3.0 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 Ank_2 PF12796.7 KFX90596.1 - 4.6e-78 257.9 34.1 1.9e-13 50.8 0.3 6.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX90596.1 - 1.1e-41 140.7 12.6 1.5e-06 28.7 0.0 9.3 6 2 5 11 11 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX90596.1 - 5e-36 118.6 6.4 0.031 14.8 0.0 13.2 13 0 0 13 13 12 8 Ankyrin repeat Ank PF00023.30 KFX90596.1 - 5.9e-31 105.6 26.1 0.0039 17.6 0.0 12.5 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KFX90596.1 - 1.8e-19 69.5 11.3 0.0014 18.9 0.0 9.2 1 1 9 11 11 11 8 Ankyrin repeats (many copies) DUF676 PF05057.14 KFX90596.1 - 0.00014 21.5 0.0 0.00066 19.2 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.12 KFX90596.1 - 0.00033 20.6 0.0 0.00098 19.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 KFX90596.1 - 0.00079 19.2 0.3 0.0022 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX90596.1 - 0.0071 16.6 0.0 0.03 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF5507 PF17612.2 KFX90596.1 - 0.022 14.5 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5507) Hydrolase_4 PF12146.8 KFX90596.1 - 0.034 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_helicase PF00910.22 KFX90596.1 - 0.039 14.3 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KFX90596.1 - 0.043 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX90596.1 - 0.052 12.7 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KFX90596.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KFX90596.1 - 0.097 11.9 0.1 2.5 7.3 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 KFX90596.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 KFX90596.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ploopntkinase3 PF18751.1 KFX90596.1 - 0.14 12.0 0.1 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PilX PF13681.6 KFX90596.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term FAD_binding_8 PF08022.12 KFX90597.1 - 9.1e-22 77.2 0.0 1.8e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX90597.1 - 1e-20 74.4 0.0 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFX90597.1 - 7.2e-19 68.1 9.4 7.2e-19 68.1 9.4 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KFX90597.1 - 0.0039 17.5 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain F-box-like PF12937.7 KFX90598.1 - 0.039 13.8 1.1 0.6 10.0 1.1 2.4 1 1 0 1 1 1 0 F-box-like F-box-like_2 PF13013.6 KFX90598.1 - 0.1 12.6 0.2 0.31 11.0 0.2 1.9 1 1 0 1 1 1 0 F-box-like domain DUF123 PF01986.16 KFX90603.1 - 0.021 15.3 0.0 0.073 13.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF123 2-oxogl_dehyd_N PF16078.5 KFX90603.1 - 0.55 9.9 2.4 1.2 8.8 2.4 1.6 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 KFX90609.1 - 1.2e-87 293.7 2.7 1.4e-87 293.4 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFX90609.1 - 6.6e-47 158.7 0.0 1.5e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 KFX90609.1 - 0.0069 16.2 0.6 0.019 14.8 0.6 1.8 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NAD_binding_7 PF13241.6 KFX90609.1 - 0.026 15.0 0.0 0.063 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 KFX90612.1 - 4.7e-15 55.3 0.7 8.2e-15 54.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90612.1 - 1.4e-07 31.5 11.5 2.3e-07 30.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX90613.1 - 2.2e-33 115.7 74.8 1.1e-28 100.2 50.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX90613.1 - 0.008 14.5 0.0 0.008 14.5 0.0 3.0 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF2855 PF11017.8 KFX90614.1 - 1.4e-76 258.5 0.0 1.6e-76 258.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) tRNA-synt_1g PF09334.11 KFX90614.1 - 0.03 13.1 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) Acyl-CoA_dh_1 PF00441.24 KFX90615.1 - 4.9e-33 114.5 0.9 7e-33 114.0 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX90615.1 - 6.1e-22 77.6 0.1 1.2e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX90615.1 - 3.1e-14 53.6 0.1 2.8e-13 50.5 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFX90615.1 - 1.6e-05 25.2 0.1 2.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 KFX90616.1 - 9.1e-28 96.9 0.0 1.6e-27 96.1 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFX90616.1 - 0.0015 18.7 0.0 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFX90616.1 - 0.022 14.3 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Acetyltransf_10 PF13673.7 KFX90617.1 - 1.2e-08 34.9 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX90617.1 - 2.9e-07 30.7 0.0 5.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX90617.1 - 8.3e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX90617.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFX90617.1 - 0.0013 18.8 0.0 0.008 16.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain UDG PF03167.19 KFX90617.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Acetyltransf_CG PF14542.6 KFX90617.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CTP_transf_like PF01467.26 KFX90619.1 - 0.0014 18.9 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like Utp12 PF04003.12 KFX90628.1 - 5.8e-08 33.0 0.0 7.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.10 KFX90628.1 - 0.099 12.0 20.9 0.12 11.7 20.9 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.11 KFX90628.1 - 0.13 12.0 10.0 0.19 11.4 10.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 KFX90628.1 - 0.8 7.8 25.5 0.91 7.7 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFX90628.1 - 2.9 7.3 28.6 3.9 6.8 28.6 1.1 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 KFX90629.1 - 4.9e-16 58.9 0.0 1.4e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90629.1 - 8.1e-07 28.6 0.0 1.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3720 PF12517.8 KFX90629.1 - 1.1 10.3 5.3 47 5.0 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) Arginase PF00491.21 KFX90631.1 - 2.1e-43 148.8 0.1 2.4e-43 148.7 0.1 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.8 KFX90632.1 - 1.5e-38 132.7 2.3 1.9e-38 132.3 2.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90632.1 - 0.013 15.6 13.0 0.038 14.1 13.0 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DHNA PF04038.12 KFX90632.1 - 0.19 12.3 0.0 0.56 10.8 0.0 1.7 2 0 0 2 2 2 0 Dihydroneopterin aldolase Acatn PF13000.7 KFX90633.1 - 1.1e-145 486.3 29.1 4.2e-82 276.4 7.8 3.7 2 1 2 4 4 4 3 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 KFX90633.1 - 2e-28 99.3 64.9 2e-23 82.9 24.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX90633.1 - 0.0013 17.7 7.8 0.0013 17.7 7.8 2.6 3 0 0 3 3 3 2 MFS_1 like family ADH_N PF08240.12 KFX90634.1 - 2.7e-28 98.0 0.2 6.9e-28 96.7 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX90634.1 - 6.6e-11 42.3 2.8 1.3e-10 41.3 2.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX90634.1 - 5.1e-06 26.1 1.3 0.067 12.7 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KFX90634.1 - 9.3e-05 21.3 0.4 0.00014 20.7 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX90634.1 - 0.00012 21.5 0.6 0.00018 20.8 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KFX90634.1 - 0.0014 18.8 2.2 0.0017 18.5 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX90634.1 - 0.0017 17.5 2.5 0.0017 17.5 2.5 1.5 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 KFX90634.1 - 0.0019 18.1 0.6 0.0027 17.6 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX90634.1 - 0.0057 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX90634.1 - 0.0098 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFX90634.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.14 KFX90634.1 - 0.014 14.6 1.4 0.054 12.7 0.2 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX90634.1 - 0.053 12.8 0.6 0.087 12.1 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX90634.1 - 0.073 12.7 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 KFX90634.1 - 0.097 13.2 0.1 0.34 11.4 0.2 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox PF00070.27 KFX90634.1 - 0.1 13.1 0.2 0.26 11.8 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KFX90634.1 - 0.15 13.2 0.1 0.52 11.4 0.1 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Thi4 PF01946.17 KFX90634.1 - 0.29 10.4 4.2 2.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KFX90634.1 - 0.38 9.8 2.9 0.57 9.2 2.9 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A DUF647 PF04884.14 KFX90638.1 - 2.3e-88 295.9 0.4 2.8e-88 295.6 0.4 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PRELI PF04707.14 KFX90639.1 - 7.8e-44 149.3 0.6 9.1e-44 149.0 0.6 1.0 1 0 0 1 1 1 1 PRELI-like family SH3_10 PF17902.1 KFX90639.1 - 0.036 14.1 0.1 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 SH3 domain AhpC-TSA PF00578.21 KFX90640.1 - 1.8e-24 86.0 0.0 3.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFX90640.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFX90640.1 - 0.0011 19.0 0.1 0.0082 16.2 0.0 2.1 2 1 1 3 3 3 1 AhpC/TSA antioxidant enzyme Cpn10 PF00166.21 KFX90641.1 - 1e-25 89.6 0.0 1.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Chitin_bind_1 PF00187.19 KFX90641.1 - 2.4e-07 31.1 17.2 3.7e-07 30.5 16.6 1.6 1 1 0 1 1 1 1 Chitin recognition protein RNase_P_Rpp14 PF01900.19 KFX90642.1 - 2.3e-37 127.3 0.0 4.6e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KFX90643.1 - 9.8e-75 251.4 1.0 1.1e-74 251.3 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFX90643.1 - 0.0015 17.6 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KFX90643.1 - 0.0048 16.8 0.0 0.83 9.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_10 PF12846.7 KFX90643.1 - 0.0085 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.6 KFX90643.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX90643.1 - 0.045 13.5 0.5 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFX90643.1 - 0.066 13.8 0.2 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.6 KFX90643.1 - 0.4 11.2 2.9 0.86 10.1 2.9 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MoCF_biosynth PF00994.24 KFX90644.1 - 7.8e-54 181.3 0.1 8.8e-26 90.3 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFX90644.1 - 2.9e-37 127.8 1.2 5.5e-37 126.9 1.2 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFX90644.1 - 1.1e-15 57.5 1.1 3.9e-15 55.8 0.1 2.5 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) WD40 PF00400.32 KFX90644.1 - 3.4e-09 37.2 1.8 0.28 12.1 0.3 5.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90644.1 - 0.12 12.7 0.0 9.5 6.6 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Voltage_CLC PF00654.20 KFX90645.1 - 7.2e-88 295.2 25.9 7.2e-88 295.2 25.9 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFX90645.1 - 8.7e-14 51.7 0.1 1.2e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 KFX90646.1 - 6.1e-44 150.4 0.0 9.7e-44 149.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90646.1 - 3e-19 69.3 0.0 9e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX90646.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFX90646.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF2781 PF10914.8 KFX90646.1 - 0.18 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) zf-C3HC PF07967.13 KFX90655.1 - 2.4e-32 111.7 0.0 6e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 C3HC zinc finger-like Rsm1 PF08600.10 KFX90655.1 - 4.3e-14 52.4 2.8 2.7e-12 46.7 0.0 2.9 2 1 0 2 2 2 2 Rsm1-like BIR PF00653.21 KFX90655.1 - 0.023 15.3 0.1 0.68 10.6 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Inositol_P PF00459.25 KFX90656.1 - 7.3e-53 179.8 1.7 1.7e-52 178.6 1.7 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 KFX90657.1 - 1.7e-22 79.9 0.0 1.9e-11 44.4 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 ApoLp-III PF07464.11 KFX90658.1 - 0.0067 16.5 6.7 0.026 14.6 6.4 2.0 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) AAA_16 PF13191.6 KFX90658.1 - 0.034 14.6 1.6 0.11 12.9 1.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF3450 PF11932.8 KFX90658.1 - 0.038 13.3 12.6 0.35 10.2 8.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin PF00804.25 KFX90658.1 - 0.06 13.0 0.2 0.06 13.0 0.2 2.7 1 1 2 3 3 3 0 Syntaxin Tht1 PF04163.12 KFX90658.1 - 0.3 9.8 7.0 0.67 8.6 6.9 1.5 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein CENP-F_leu_zip PF10473.9 KFX90658.1 - 0.3 11.1 4.7 4.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 KFX90658.1 - 0.38 10.0 4.1 0.31 10.3 0.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein FH2 PF02181.23 KFX90658.1 - 0.42 9.7 5.2 0.42 9.7 0.2 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain NPV_P10 PF05531.12 KFX90658.1 - 0.52 10.8 4.6 12 6.5 0.2 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG6 PF06419.11 KFX90658.1 - 0.64 8.2 6.8 1 7.5 0.2 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 ZYG-11_interact PF05884.12 KFX90658.1 - 1.6 8.1 7.0 7.4 5.9 5.3 2.5 1 1 2 3 3 3 0 Interactor of ZYG-11 WXG100 PF06013.12 KFX90658.1 - 1.9 8.7 15.0 1.9 8.7 0.6 3.5 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Spc7 PF08317.11 KFX90658.1 - 2.3 7.0 11.7 1.3 7.8 5.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein BRO1 PF03097.18 KFX90662.1 - 5.6e-111 371.1 0.0 6.7e-111 370.8 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain BCDHK_Adom3 PF10436.9 KFX90663.1 - 4.1e-74 247.8 0.0 6.2e-74 247.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFX90663.1 - 7.1e-13 49.0 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFX90663.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serine_rich PF08824.10 KFX90663.1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF2415 PF10313.9 KFX90665.1 - 2.6e-12 46.5 0.0 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) N_NLPC_P60 PF12912.7 KFX90665.1 - 0.016 15.6 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term HSP70 PF00012.20 KFX90666.1 - 4.8e-264 877.1 15.3 5.5e-264 876.9 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFX90666.1 - 9.3e-15 54.3 4.7 1.5e-12 47.0 1.4 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFX90666.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KFX90666.1 - 0.027 13.7 4.1 0.12 11.6 0.1 2.8 3 1 1 4 4 4 0 StbA protein Big_3_4 PF13754.6 KFX90666.1 - 0.12 12.1 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function FtsA PF14450.6 KFX90666.1 - 0.13 12.7 7.3 1.4 9.4 0.3 3.9 3 2 0 3 3 3 0 Cell division protein FtsA Toxin-deaminase PF14424.6 KFX90666.1 - 0.46 10.6 2.4 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases EcoR124_C PF12008.8 KFX90666.1 - 0.49 10.0 7.7 1 9.0 7.7 1.5 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal TarH PF02203.15 KFX90666.1 - 0.51 10.2 4.6 1.1 9.1 3.6 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF4363 PF14276.6 KFX90666.1 - 1.1 9.4 5.6 2.2 8.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) eIF3g PF12353.8 KFX90667.1 - 5.1e-44 149.7 6.8 8.3e-44 149.0 6.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KFX90667.1 - 4.6e-17 61.6 0.1 7.6e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX90667.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_7 PF18586.1 KFX90667.1 - 0.062 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 F-box PF00646.33 KFX90669.1 - 0.0075 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain SUR7 PF06687.12 KFX90670.1 - 4.9e-33 114.5 2.0 5.4e-33 114.4 2.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KFX90670.1 - 0.0035 17.3 3.7 0.0054 16.7 3.7 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF373 PF04123.13 KFX90670.1 - 0.15 11.5 5.6 0.21 11.0 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1772 PF08592.11 KFX90670.1 - 1.3 9.3 14.8 0.93 9.8 7.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2207 PF09972.9 KFX90670.1 - 6 5.5 8.9 9.1 4.9 8.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FAD_binding_3 PF01494.19 KFX90683.1 - 4.7e-14 52.4 0.0 3.6e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFX90683.1 - 2.3e-05 24.5 0.0 5.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX90683.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX90683.1 - 0.0028 16.8 0.0 0.096 11.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX90683.1 - 0.0038 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFX90683.1 - 0.0061 15.6 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KFX90683.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase A2M_BRD PF07703.14 KFX90683.1 - 0.031 14.6 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Alpha-2-macroglobulin bait region domain Pyr_redox PF00070.27 KFX90683.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFX90683.1 - 0.2 11.9 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KFX90683.1 - 0.3 10.3 0.5 0.57 9.4 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Beta-lactamase PF00144.24 KFX90684.1 - 2.2e-43 148.8 0.0 2.9e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KFX90684.1 - 0.0046 16.6 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KFX90684.1 - 0.097 12.1 0.0 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AflR PF08493.10 KFX90686.1 - 8.7e-08 32.0 0.5 1.2e-07 31.5 0.5 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein PEP_mutase PF13714.6 KFX90687.1 - 3.5e-38 131.4 0.1 4.3e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFX90687.1 - 2.5e-18 65.9 0.2 3.6e-18 65.4 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.16 KFX90688.1 - 1.1e-22 80.5 41.9 3.6e-22 78.8 41.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4728 PF15860.5 KFX90688.1 - 0.014 16.1 0.1 0.014 16.1 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) Phage_holin_8 PF16931.5 KFX90688.1 - 0.92 9.5 12.0 2.8 7.9 0.1 4.0 3 1 1 4 4 4 0 Putative phage holin HSP70 PF00012.20 KFX90689.1 - 8.8e-170 565.8 2.8 8.8e-170 565.8 2.8 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KFX90689.1 - 1.6e-12 46.9 0.2 9.5e-12 44.4 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFX90689.1 - 0.035 14.5 0.8 4.8 7.7 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA Apolipoprotein PF01442.18 KFX90689.1 - 0.049 13.5 15.3 0.2 11.5 2.7 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain BcrAD_BadFG PF01869.20 KFX90689.1 - 0.054 13.0 0.1 0.37 10.2 0.1 2.2 1 1 1 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family zf-BED PF02892.15 KFX90690.1 - 0.0097 15.9 0.3 0.0097 15.9 0.3 2.1 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.18 KFX90690.1 - 0.024 14.7 8.2 0.054 13.6 8.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GCP_N_terminal PF17681.1 KFX90691.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Carn_acyltransf PF00755.20 KFX90692.1 - 1.7e-202 674.2 0.0 2e-202 674.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.13 KFX90692.1 - 3.3e-25 88.5 0.1 8e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 CDC27 PF09507.10 KFX90692.1 - 0.15 11.4 6.9 0.24 10.7 6.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FoP_duplication PF13865.6 KFX90692.1 - 0.75 10.4 22.3 0.7 10.5 6.1 2.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ank_2 PF12796.7 KFX90693.1 - 2.9e-14 53.4 0.1 6.9e-05 23.4 0.0 7.0 4 1 2 6 6 6 3 Ankyrin repeats (3 copies) NACHT PF05729.12 KFX90693.1 - 8.5e-06 25.8 0.1 3.8e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 KFX90693.1 - 1.1e-05 25.4 0.3 0.27 11.9 0.0 7.2 9 0 0 9 9 4 1 Ankyrin repeat AAA_22 PF13401.6 KFX90693.1 - 1.7e-05 25.2 0.0 6.1e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX90693.1 - 2.3e-05 24.9 0.1 0.0002 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank PF00023.30 KFX90693.1 - 0.00018 21.8 0.0 0.21 12.1 0.0 4.8 4 0 0 4 4 2 1 Ankyrin repeat Ank_4 PF13637.6 KFX90693.1 - 0.00026 21.5 0.0 0.0072 16.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX90693.1 - 0.0014 18.9 0.0 5 7.6 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AAA_19 PF13245.6 KFX90693.1 - 0.0045 17.3 0.1 0.055 13.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFX90693.1 - 0.018 14.2 0.0 0.058 12.6 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain SesA PF17107.5 KFX90693.1 - 0.049 13.8 1.7 0.18 12.0 0.4 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DNA_repr_REX1B PF14966.6 KFX90693.1 - 0.05 14.3 1.4 0.38 11.4 0.1 2.8 3 0 0 3 3 3 0 DNA repair REX1-B Helicase_C_3 PF13625.6 KFX90693.1 - 0.086 13.0 0.0 7.1 6.8 0.0 3.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DEP PF00610.21 KFX90693.1 - 0.09 12.8 0.3 63 3.7 0.0 4.3 6 0 0 6 6 5 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Vps52 PF04129.12 KFX90694.1 - 1.2e-119 400.3 1.4 1.7e-119 399.9 1.4 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KFX90694.1 - 0.0038 15.7 1.4 0.0076 14.7 1.5 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec3 ubiquitin PF00240.23 KFX90695.1 - 6.1e-33 112.4 0.9 1.3e-32 111.4 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 KFX90695.1 - 1.5e-30 104.8 10.7 3.1e-30 103.8 10.7 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KFX90695.1 - 3.7e-15 55.5 0.7 7.8e-15 54.5 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like eIF-5a PF01287.20 KFX90695.1 - 3.7e-13 49.4 0.9 8.1e-13 48.3 0.9 1.6 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Ubiquitin_2 PF14560.6 KFX90695.1 - 0.0005 20.5 0.1 0.0016 18.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KFX90695.1 - 0.02 15.2 0.2 0.059 13.7 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KFX90695.1 - 0.023 14.6 0.1 0.087 12.8 0.1 1.9 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain EFP_N PF08207.12 KFX90695.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DUF3029 PF11230.8 KFX90695.1 - 0.15 10.4 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) RabGAP-TBC PF00566.18 KFX90696.1 - 4.6e-23 82.0 0.0 7.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 KFX90697.1 - 2.2e-68 231.1 0.0 3.4e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 KFX90698.1 - 4.4e-33 114.5 0.0 4.4e-33 114.5 0.0 2.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFX90698.1 - 1.8e-19 69.8 0.0 4.9e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KFX90698.1 - 2.1e-09 37.6 1.9 2.7e-07 30.9 0.1 3.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KFX90698.1 - 7.7e-08 32.1 0.2 4.4e-07 29.7 0.2 2.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KFX90698.1 - 5.7e-07 29.6 0.2 5.6e-06 26.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFX90698.1 - 0.00083 19.6 0.0 0.0026 17.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KFX90698.1 - 0.0035 17.2 0.3 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein EthD PF07110.11 KFX90699.1 - 4.2e-21 75.9 0.0 6.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 EthD domain His_Phos_2 PF00328.22 KFX90707.1 - 2.4e-57 195.0 0.0 2.8e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rot1 PF10681.9 KFX90708.1 - 3.6e-08 33.2 0.1 4.1e-08 33.0 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Ribo_biogen_C PF04034.13 KFX90717.1 - 6.7e-50 168.1 0.0 9e-50 167.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal BUD22 PF09073.10 KFX90717.1 - 1.4 8.1 15.1 1.9 7.7 15.1 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KFX90717.1 - 9.1 4.4 9.2 11 4.2 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Defensin_2 PF01097.18 KFX90718.1 - 0.0012 18.7 9.4 0.0036 17.2 9.4 1.9 1 0 0 1 1 1 1 Arthropod defensin APH PF01636.23 KFX90719.1 - 1.6e-06 28.2 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX90719.1 - 0.00089 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 KFX90719.1 - 0.087 11.7 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Prok-RING_1 PF14446.6 KFX90720.1 - 0.0032 17.4 5.5 0.0065 16.4 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KFX90720.1 - 0.0088 15.8 5.2 0.015 15.1 5.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.21 KFX90720.1 - 0.025 14.7 5.2 0.021 14.9 4.6 1.4 1 1 0 1 1 1 0 FYVE zinc finger zf-piccolo PF05715.13 KFX90720.1 - 0.07 13.3 3.8 0.14 12.3 3.8 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger Prok-RING_2 PF14445.6 KFX90720.1 - 0.092 12.9 3.0 0.17 12.1 3.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Baculo_IE-1 PF05290.11 KFX90720.1 - 0.26 11.3 3.1 0.5 10.3 3.1 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 KFX90720.1 - 0.35 11.2 5.6 0.64 10.4 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 KFX90720.1 - 0.36 10.8 5.9 0.72 9.8 5.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-B_box PF00643.24 KFX90720.1 - 0.38 11.0 7.8 1.3 9.2 7.8 1.9 1 1 0 1 1 1 0 B-box zinc finger DNA_RNApol_7kD PF03604.13 KFX90720.1 - 2.2 8.1 8.2 1.1 9.0 4.8 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Acyl-CoA_dh_1 PF00441.24 KFX90721.1 - 5.3e-40 137.1 0.2 5.3e-40 137.1 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX90721.1 - 9.2e-23 80.3 0.1 1.8e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX90721.1 - 4.6e-19 69.2 0.0 1.3e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 KFX90721.1 - 1.3e-17 63.7 0.2 2.6e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KFX90721.1 - 1.8e-07 31.5 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CAP_N PF01213.19 KFX90721.1 - 0.52 9.8 3.1 0.8 9.1 3.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Lipase_GDSL_2 PF13472.6 KFX90722.1 - 8.9e-22 78.3 0.2 1.7e-21 77.4 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX90722.1 - 7.1e-15 55.5 0.0 1e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ras PF00071.22 KFX90723.1 - 3.5e-36 124.3 0.0 2.2e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFX90723.1 - 1.5e-10 41.3 0.0 3.9e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFX90723.1 - 0.00098 19.2 0.0 0.0031 17.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KFX90723.1 - 0.0016 17.9 0.0 0.0067 15.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX90723.1 - 0.033 13.7 1.9 0.28 10.7 0.1 3.0 2 2 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFX90723.1 - 0.11 12.8 2.8 0.15 12.5 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KFX90723.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain PUF PF00806.19 KFX90724.1 - 8.2e-13 47.3 0.0 0.037 13.7 0.0 7.5 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat TMEM247 PF15444.6 KFX90724.1 - 0.33 11.0 1.8 24 4.9 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 247 MFS_1 PF07690.16 KFX90726.1 - 6.3e-18 64.8 41.8 1.8e-14 53.4 16.9 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX90726.1 - 8e-17 61.2 6.7 8e-17 61.2 6.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter CN_hydrolase PF00795.22 KFX90727.1 - 3.1e-18 66.0 0.0 3.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SnoaL PF07366.12 KFX90728.1 - 4e-21 75.1 0.0 6.2e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFX90728.1 - 2.5e-12 47.3 0.0 2.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Alpha-amylase PF00128.24 KFX90729.1 - 2.2e-116 389.1 0.0 4.6e-116 388.1 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX90729.1 - 8.8e-09 35.4 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX90729.1 - 0.00096 18.4 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Fungal_trans_2 PF11951.8 KFX90730.1 - 1.5e-51 175.4 4.5 2.3e-51 174.8 4.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90730.1 - 2.8e-07 30.5 9.5 5.4e-07 29.6 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_7 PF12973.7 KFX90731.1 - 1.2e-13 50.7 0.1 1.7e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF1202 PF06717.11 KFX90731.1 - 0.23 10.8 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Cupin_2 PF07883.11 KFX90731.1 - 0.34 10.7 3.2 0.45 10.3 2.0 1.8 1 1 1 2 2 2 0 Cupin domain Aminotran_3 PF00202.21 KFX90732.1 - 1.2e-83 281.1 0.0 1.6e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Methyltransf_23 PF13489.6 KFX90733.1 - 4e-17 62.5 0.0 7.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90733.1 - 7.7e-09 36.1 0.0 2.1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX90733.1 - 1e-08 35.2 0.0 1.2e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX90733.1 - 2.5e-06 28.0 0.0 6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90733.1 - 0.0011 19.6 0.0 0.0084 16.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFX90733.1 - 0.0029 17.8 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KFX90733.1 - 0.0039 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain GRDP-like PF07173.12 KFX90733.1 - 0.013 16.1 0.2 0.26 11.9 0.0 2.6 3 0 0 3 3 3 0 Glycine-rich domain-containing protein-like Methyltransf_4 PF02390.17 KFX90733.1 - 0.02 14.4 0.0 0.083 12.3 0.1 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 KFX90733.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRKCSH PF07915.13 KFX90739.1 - 4.4e-13 50.0 2.6 7.1e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pirin PF02678.16 KFX90740.1 - 5.8e-31 106.7 0.1 1e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KFX90740.1 - 3.8e-24 85.0 0.0 5.4e-23 81.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KFX90740.1 - 1.3e-06 28.0 1.6 0.00035 20.2 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFX90740.1 - 0.0016 18.1 0.5 0.22 11.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF861) TRAM_LAG1_CLN8 PF03798.16 KFX90741.1 - 1.9e-46 158.3 6.6 2.3e-46 158.1 6.6 1.0 1 0 0 1 1 1 1 TLC domain Dor1 PF04124.12 KFX90742.1 - 2.5e-53 180.9 0.9 2e-42 145.1 2.8 2.1 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 KFX90742.1 - 0.078 13.1 1.2 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Vps51/Vps67 ATP_transf PF09830.9 KFX90743.1 - 1.3e-18 66.9 0.0 2.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF829 PF05705.14 KFX90744.1 - 1.9e-50 172.1 0.1 2.2e-50 171.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ADH_N PF08240.12 KFX90745.1 - 9.8e-26 89.8 2.8 1.5e-25 89.2 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX90745.1 - 1.5e-11 44.4 0.0 2.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX90745.1 - 0.0049 16.2 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KFX90745.1 - 0.09 13.8 0.0 0.14 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Lipase_GDSL PF00657.22 KFX90746.1 - 7.4e-10 39.1 0.1 1.7e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFX90746.1 - 9.7e-09 35.9 5.4 2.8e-08 34.3 5.4 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 KFX90746.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal PRP1_N PF06424.12 KFX90750.1 - 0.00018 21.9 9.6 0.00063 20.2 9.6 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Nucleo_P87 PF07267.11 KFX90750.1 - 0.021 13.7 14.9 0.041 12.7 14.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 KFX90750.1 - 3.7 8.0 12.8 12 6.3 12.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KFX90750.1 - 4.4 6.6 10.5 11 5.3 10.5 1.6 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KFX90750.1 - 8.4 6.1 6.3 23 4.6 6.3 1.7 1 0 0 1 1 1 0 FAM176 family D-ser_dehydrat PF14031.6 KFX90756.1 - 1.4e-06 28.9 0.0 2.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain PCRF PF03462.18 KFX90760.1 - 1.1e-29 103.7 0.0 1.2e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 PCRF domain Tup_N PF08581.10 KFX90760.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Tup N-terminal RRM_1 PF00076.22 KFX90763.1 - 6.9e-10 38.6 1.4 5e-09 35.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM91_C PF14648.6 KFX90763.1 - 0.1 11.4 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus TFIIF_alpha PF05793.12 KFX90763.1 - 0.19 10.2 30.1 0.33 9.5 30.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sds3 PF08598.11 KFX90764.1 - 5.7e-16 59.2 2.4 5.7e-16 59.2 2.4 2.6 2 1 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.9 KFX90765.1 - 9e-05 22.5 0.0 9.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KFX90766.1 - 2.3e-71 240.0 0.0 7.3e-71 238.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Svf1_C PF17187.4 KFX90766.1 - 0.035 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain XPC-binding PF09280.11 KFX90766.1 - 0.078 12.7 0.1 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain SASP PF00269.20 KFX90767.1 - 0.014 15.4 0.3 11 6.1 0.0 3.6 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type Chorion_2 PF03964.15 KFX90767.1 - 0.14 13.0 0.4 0.14 13.0 0.4 2.1 2 1 1 3 3 3 0 Chorion family 2 Fib_alpha PF08702.10 KFX90767.1 - 2.7 8.2 11.9 6.9 6.8 5.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KFX90767.1 - 3.8 4.9 30.7 0.14 9.6 16.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KFX90767.1 - 7.8 5.8 25.5 5.5 6.3 22.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EF-hand_5 PF13202.6 KFX90771.1 - 9e-05 21.8 0.1 0.00022 20.6 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KFX90771.1 - 0.00082 18.7 0.5 0.0021 17.5 0.5 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX90771.1 - 0.00097 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFX90771.1 - 0.0015 19.0 0.2 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair AGH PF17558.2 KFX90771.1 - 0.17 12.0 0.8 1.7 8.8 1.0 2.5 2 1 0 2 2 2 0 Androgenic gland hormone DAO PF01266.24 KFX90772.1 - 1.9e-30 106.6 0.1 2.2e-30 106.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX90772.1 - 0.00014 21.2 0.1 0.12 11.6 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX90772.1 - 0.00046 19.4 0.2 0.038 13.0 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFX90772.1 - 0.0018 17.6 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX90772.1 - 0.0045 16.1 0.1 1.6 7.7 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KFX90772.1 - 0.0051 15.6 0.0 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KFX90772.1 - 0.0092 16.0 0.3 2.6 8.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KFX90772.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.27 KFX90772.1 - 0.056 14.0 0.1 8.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 KFX90772.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 KFX90772.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX90772.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Adaptin_N PF01602.20 KFX90777.1 - 1.2e-107 360.6 6.1 1.5e-107 360.3 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFX90777.1 - 2.9e-45 153.1 0.0 6.9e-45 151.9 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFX90777.1 - 2.2e-18 66.6 0.0 4.5e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFX90777.1 - 0.0013 18.8 0.2 0.15 12.1 0.0 2.7 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFX90777.1 - 0.12 12.6 0.3 1 9.6 0.1 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 KFX90777.1 - 0.18 10.3 3.2 0.24 9.8 0.9 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit MMS1_N PF10433.9 KFX90778.1 - 8.9e-92 308.2 0.0 1.3e-91 307.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFX90778.1 - 1.2e-68 231.9 0.0 4.1e-68 230.1 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region DUF4452 PF14618.6 KFX90786.1 - 7.7e-75 250.4 14.8 9.9e-75 250.1 14.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.19 KFX90789.1 - 2.3e-09 37.1 2.1 4.2e-09 36.3 2.1 1.5 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.18 KFX90789.1 - 0.0033 15.7 0.3 0.0034 15.7 0.3 1.1 1 0 0 1 1 1 1 Fusion glycoprotein F0 Flp1_like PF16982.5 KFX90789.1 - 0.029 13.7 4.2 0.043 13.2 4.2 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF2612 PF11041.8 KFX90789.1 - 0.032 14.2 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) DUF1676 PF07898.13 KFX90789.1 - 0.067 13.2 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) HA2 PF04408.23 KFX90792.1 - 2.2e-16 60.1 0.2 5.3e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX90792.1 - 1.8e-12 47.5 0.0 4.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX90792.1 - 6.5e-12 45.8 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFX90792.1 - 3.4e-05 24.1 0.1 9e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX90792.1 - 0.00025 20.8 0.1 0.00065 19.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFX90792.1 - 0.00037 20.3 0.1 0.00069 19.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFX90792.1 - 0.022 14.8 0.1 8.7 6.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain GDI PF00996.18 KFX90792.1 - 0.031 12.8 0.0 0.054 12.0 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor ABC_tran PF00005.27 KFX90792.1 - 0.034 14.7 0.1 0.11 13.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 KFX90792.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin NmrA PF05368.13 KFX90793.1 - 1.2e-11 44.6 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFX90793.1 - 0.017 15.5 0.1 0.055 13.9 0.1 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFX90793.1 - 0.023 14.6 0.1 0.2 11.5 0.1 2.7 1 1 0 1 1 1 0 NAD(P)H-binding Ima1_N PF09779.9 KFX90794.1 - 1.4e-36 126.3 4.3 3.1e-36 125.2 4.3 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF1430 PF07242.11 KFX90794.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DZR PF12773.7 KFX90794.1 - 0.14 12.2 4.1 4.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFX90794.1 - 2.6 7.8 6.3 3 7.6 0.7 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein Adeno_E3_CR2 PF02439.15 KFX90797.1 - 3.2e-05 23.6 3.8 5e-05 23.0 3.8 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1180 PF06679.12 KFX90797.1 - 7.3e-05 23.2 0.3 7.3e-05 23.2 0.3 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) SKG6 PF08693.10 KFX90797.1 - 0.0018 17.6 5.7 0.004 16.5 5.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KFX90797.1 - 0.007 16.3 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family Mid2 PF04478.12 KFX90797.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glycophorin_A PF01102.18 KFX90797.1 - 0.028 14.7 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 KFX90797.1 - 0.031 15.1 0.0 0.17 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 KFX90797.1 - 0.19 11.3 0.0 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family Band_7 PF01145.25 KFX90799.1 - 3.8e-26 92.2 1.1 6e-26 91.5 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spindle_Spc25 PF08234.12 KFX90801.1 - 2.9e-24 85.1 0.4 8.8e-24 83.5 0.0 2.0 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Macoilin PF09726.9 KFX90801.1 - 0.054 12.0 6.3 0.067 11.8 6.3 1.0 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 KFX90801.1 - 0.083 11.8 5.6 0.12 11.3 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PRTP PF01366.18 KFX90801.1 - 0.51 8.3 4.8 0.63 8.0 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein APG6_N PF17675.1 KFX90801.1 - 1.6 9.2 10.2 3.2 8.3 10.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Med21 PF11221.8 KFX90801.1 - 2.7 8.2 8.9 9.7 6.4 9.1 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Rrn6 PF10214.9 KFX90807.1 - 2.7e-161 539.0 0.0 3.6e-161 538.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Pkinase PF00069.25 KFX90813.1 - 5.1e-51 173.6 0.0 6.1e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90813.1 - 1.2e-26 93.6 0.0 1.3e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX90813.1 - 0.00065 18.7 0.1 0.0095 14.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFX90813.1 - 0.0033 17.4 0.1 0.0062 16.5 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFX90813.1 - 0.011 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFX90813.1 - 0.065 12.6 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX90813.1 - 0.098 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 2OG-FeII_Oxy_2 PF13532.6 KFX90814.1 - 4e-33 115.3 0.0 5.3e-32 111.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 KFX90815.1 - 2.1e-102 343.4 0.0 2.8e-102 343.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Phage_Mu_Gam PF07352.12 KFX90815.1 - 0.072 13.0 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF807 PF05660.11 KFX90815.1 - 0.075 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) SNF2_N PF00176.23 KFX90816.1 - 3.1e-66 223.5 0.3 1.6e-64 217.8 0.3 2.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX90816.1 - 1.4e-15 57.6 0.0 3.6e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX90816.1 - 2.6e-06 27.6 0.0 5.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX90816.1 - 0.00056 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase NAD_binding_10 PF13460.6 KFX90817.1 - 2.3e-07 30.9 0.2 2.9e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX90817.1 - 1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.10 KFX90817.1 - 1.4e-06 27.9 0.0 3.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 HIM1 Epimerase PF01370.21 KFX90817.1 - 5.6e-05 22.7 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX90817.1 - 0.0095 15.0 0.0 0.034 13.1 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFX90817.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFX90817.1 - 0.026 13.7 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 KFX90817.1 - 0.039 13.1 0.1 0.67 9.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_1 PF00667.20 KFX90818.1 - 5.8e-63 212.4 0.0 1e-62 211.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KFX90818.1 - 2.7e-11 43.9 0.0 6.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KFX90818.1 - 6.1e-10 39.7 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KFX90818.1 - 1e-06 29.0 1.4 1.9e-06 28.1 0.2 2.1 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KFX90818.1 - 0.0062 16.4 0.1 0.025 14.5 0.1 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 KFX90818.1 - 0.08 13.3 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain ArfGap PF01412.18 KFX90824.1 - 0.015 15.3 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Sugar_tr PF00083.24 KFX90834.1 - 5.1e-77 259.6 21.1 6e-77 259.4 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90834.1 - 1.6e-13 50.3 25.7 1.6e-13 50.3 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C7 PF01830.18 KFX90834.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family RraA-like PF03737.15 KFX90835.1 - 6.4e-34 117.3 0.3 7.9e-34 117.0 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA 2-Hacid_dh_C PF02826.19 KFX90836.1 - 5.6e-55 185.4 0.0 7.7e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX90836.1 - 1.8e-26 92.4 0.0 2.3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX90836.1 - 0.0001 22.5 0.1 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 KFX90836.1 - 0.032 14.6 0.3 0.27 11.6 0.1 2.4 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFX90836.1 - 0.035 14.7 0.1 0.11 13.1 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KFX90836.1 - 0.42 10.9 2.6 68 3.7 0.0 3.7 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Ldh_2 PF02615.14 KFX90837.1 - 2.3e-116 388.6 0.3 2.6e-116 388.4 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Gly_rich_SFCGS PF14272.6 KFX90837.1 - 0.048 13.7 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Glycine-rich SFCGS MFS_1 PF07690.16 KFX90838.1 - 1.3e-26 93.4 24.1 1.3e-26 93.4 24.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KFX90839.1 - 2.5e-25 89.9 0.1 3.7e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 KFX90839.1 - 1.4e-22 80.0 0.1 2.3e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90839.1 - 3.8e-08 33.3 9.6 7.1e-08 32.5 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBA_3 PF09288.10 KFX90839.1 - 0.22 11.3 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain adh_short PF00106.25 KFX90842.1 - 7.3e-15 54.9 0.0 2.3e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90842.1 - 1e-07 31.8 0.0 5.6e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90842.1 - 3.1e-06 27.2 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.12 KFX90842.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 NACHT domain DDR_swiveling PF18427.1 KFX90842.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain Fib_alpha PF08702.10 KFX90845.1 - 0.031 14.5 0.2 0.068 13.4 0.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-C2H2_aberr PF17017.5 KFX90845.1 - 0.05 13.8 0.1 0.97 9.6 0.0 2.7 3 0 0 3 3 3 0 Aberrant zinc-finger AOX PF01786.17 KFX90846.1 - 1.9e-93 312.0 0.1 2.4e-93 311.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short PF00106.25 KFX90851.1 - 5.1e-37 127.2 0.4 7.8e-37 126.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90851.1 - 7.8e-30 104.2 0.7 1e-29 103.8 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90851.1 - 4.8e-11 42.9 0.2 7e-11 42.4 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX90851.1 - 0.00027 20.9 0.1 0.00038 20.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX90851.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KFX90851.1 - 0.013 15.3 0.1 0.049 13.4 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.26 KFX90851.1 - 0.051 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 KFX90851.1 - 0.11 12.1 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Sugar_tr PF00083.24 KFX90852.1 - 5.2e-94 315.7 16.4 6.5e-94 315.3 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90852.1 - 1.3e-32 113.1 46.1 2.1e-26 92.7 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Claudin_2 PF13903.6 KFX90852.1 - 0.088 12.6 5.4 0.12 12.1 0.1 3.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction AnmK PF03702.14 KFX90853.1 - 1.2e-89 301.0 0.0 1.4e-89 300.7 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Methyltransf_2 PF00891.18 KFX90853.1 - 0.00081 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Peptidase_M22 PF00814.25 KFX90853.1 - 0.0093 15.7 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 1 Glycoprotease family Fibrillarin_2 PF10113.9 KFX90853.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein AnmK PF03702.14 KFX90854.1 - 5.8e-63 213.2 0.0 3.2e-62 210.8 0.0 1.8 1 1 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Sugar_tr PF00083.24 KFX90855.1 - 4.3e-94 315.9 19.3 5.3e-94 315.6 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90855.1 - 7.2e-26 90.9 42.9 1.7e-23 83.1 22.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX90855.1 - 0.00048 18.8 14.4 0.021 13.4 1.2 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Fungal_trans_2 PF11951.8 KFX90856.1 - 1.3e-10 40.6 13.7 2.3e-10 39.9 13.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90856.1 - 6.8 6.9 6.3 0.36 11.0 0.6 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX90857.1 - 1.2e-14 54.0 0.1 2.1e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90857.1 - 0.00048 20.2 10.8 0.00088 19.3 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX90858.1 - 1.9e-28 99.3 0.0 2.8e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90858.1 - 3.6e-08 33.4 11.8 5.9e-08 32.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KFX90858.1 - 8.9e-05 22.6 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.24 KFX90859.1 - 1.8e-117 393.0 16.6 2.9e-117 392.3 16.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90859.1 - 3.3e-21 75.6 44.6 1.5e-10 40.5 20.1 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily PRK PF00485.18 KFX90860.1 - 1.4e-06 28.2 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFX90860.1 - 0.00043 20.8 0.1 0.0021 18.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX90860.1 - 0.00091 19.4 0.3 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX90860.1 - 0.0024 17.6 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX90860.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KFX90860.1 - 0.0033 17.8 0.0 0.0059 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KFX90860.1 - 0.0033 16.7 0.0 0.0073 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 KFX90860.1 - 0.0095 15.2 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain Ploopntkinase3 PF18751.1 KFX90860.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 KFX90860.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.20 KFX90860.1 - 0.042 13.5 0.7 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase MeaB PF03308.16 KFX90860.1 - 0.044 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KFX90860.1 - 0.045 13.1 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFX90860.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KFX90860.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 KFX90860.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KFX90860.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KFX90860.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFX90860.1 - 0.17 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Dicty_CAR PF05462.11 KFX90861.1 - 6.2e-13 48.5 14.1 8.2e-13 48.1 7.8 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFX90861.1 - 2.7e-08 33.5 4.7 3.4e-08 33.1 4.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFX90861.1 - 0.00011 22.1 11.0 0.00011 22.1 11.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Adeno_E3_CR2 PF02439.15 KFX90861.1 - 0.086 12.6 0.1 0.26 11.1 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ABC2_membrane PF01061.24 KFX90875.1 - 4.4e-48 163.5 36.6 1.6e-26 93.1 8.5 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX90875.1 - 3.8e-34 118.1 0.0 6.2e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFX90875.1 - 4.3e-12 46.4 0.1 0.00094 19.1 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX90875.1 - 3.3e-05 23.4 0.1 0.056 12.9 0.1 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX90875.1 - 0.00012 22.7 0.0 0.0002 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX90875.1 - 0.0015 19.0 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 KFX90875.1 - 0.0015 18.7 0.8 2.8 8.2 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFX90875.1 - 0.0051 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX90875.1 - 0.0077 16.2 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase PDR_assoc PF08370.11 KFX90875.1 - 0.015 15.0 0.4 0.076 12.8 0.2 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_22 PF13401.6 KFX90875.1 - 0.028 14.7 0.0 0.089 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KFX90875.1 - 0.097 12.2 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX90875.1 - 0.14 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KFX90875.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MGC-24 PF05283.11 KFX90876.1 - 0.00015 22.2 2.9 0.00023 21.6 2.9 1.3 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KFX90876.1 - 0.001 18.9 0.2 0.0019 18.1 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.10 KFX90876.1 - 0.002 17.5 1.4 0.0065 15.9 1.4 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SOG2 PF10428.9 KFX90876.1 - 0.02 14.1 1.8 0.025 13.8 1.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Syndecan PF01034.20 KFX90876.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KFX90876.1 - 0.26 11.1 2.0 0.47 10.3 2.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_Omp PF13488.6 KFX90877.1 - 0.057 13.4 2.7 0.11 12.5 2.7 1.4 1 0 0 1 1 1 0 Glycine zipper TMEM154 PF15102.6 KFX90877.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.5 1 1 1 2 2 2 0 TMEM154 protein family CCDC50_N PF15295.6 KFX90877.1 - 0.17 12.0 1.0 0.73 10.0 1.1 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF4690 PF15756.5 KFX90877.1 - 2 9.1 9.8 0.087 13.4 1.8 2.6 1 1 1 2 2 2 0 Small Novel Rich in Cartilage SOG2 PF10428.9 KFX90877.1 - 6.1 5.9 21.2 11 5.1 21.2 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein MGC-24 PF05283.11 KFX90877.1 - 9.2 6.7 19.9 0.21 12.0 3.4 2.3 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ndc1_Nup PF09531.10 KFX90877.1 - 9.6 4.8 9.4 14 4.2 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAP59_mtransfer PF11735.8 KFX90878.1 - 7.5e-69 232.1 0.0 9.8e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 APH PF01636.23 KFX90879.1 - 0.00016 21.7 0.0 0.00067 19.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family ADH_zinc_N PF00107.26 KFX90880.1 - 1e-06 28.7 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX90880.1 - 6.6e-05 22.8 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rep_1B PF17873.1 KFX90880.1 - 0.034 14.0 0.1 0.81 9.6 0.0 2.6 2 0 0 2 2 2 0 Replicase polyprotein 1ab SSF PF00474.17 KFX90881.1 - 1.8e-21 76.5 30.8 3e-21 75.8 30.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Bac_luciferase PF00296.20 KFX90882.1 - 6.6e-55 186.7 0.2 8.6e-55 186.4 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 KFX90882.1 - 0.005 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Glyco_hydro_43 PF04616.14 KFX90883.1 - 6.4e-14 52.0 0.1 1.5e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans_2 PF11951.8 KFX90883.1 - 0.00085 18.2 0.1 0.0068 15.3 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_N PF02798.20 KFX90884.1 - 4.7e-07 30.1 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAD_binding_1 PF00175.21 KFX90884.1 - 2e-06 28.4 0.0 4.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFX90884.1 - 2.4e-05 24.6 0.0 0.005 17.2 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFX90884.1 - 2.8e-05 24.3 0.0 0.00017 21.8 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain GST_N_3 PF13417.6 KFX90884.1 - 4.6e-05 23.7 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Putative_PNPOx PF01243.20 KFX90884.1 - 0.00056 20.0 0.0 2.5 8.4 0.0 3.0 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.25 KFX90884.1 - 0.00092 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX90884.1 - 0.00093 19.5 0.0 0.0028 17.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX90885.1 - 1.3e-17 63.8 0.0 2.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX90885.1 - 9.2e-06 25.9 0.0 3.2e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX90885.1 - 0.0053 16.9 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX90885.1 - 0.0083 16.1 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX90885.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.18 KFX90886.1 - 3.6e-07 30.2 13.4 1.1e-06 28.6 13.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX90886.1 - 1.6e-06 27.4 0.2 3.6e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain TraW_N PF12477.8 KFX90886.1 - 0.083 12.9 0.6 0.21 11.6 0.6 1.6 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Ribosomal_L37ae PF01780.19 KFX90886.1 - 1.5 8.9 4.0 1.8 8.7 2.5 1.9 2 0 0 2 2 2 0 Ribosomal L37ae protein family GMC_oxred_N PF00732.19 KFX90887.1 - 1.7e-47 162.2 0.0 2.4e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX90887.1 - 2e-33 116.0 0.1 3.7e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFX90887.1 - 9.2e-06 24.9 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFX90887.1 - 8.8e-05 22.2 0.1 0.023 14.3 0.1 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX90887.1 - 0.0012 18.1 0.0 0.099 11.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFX90887.1 - 0.0015 18.7 0.6 0.0072 16.5 0.0 2.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX90887.1 - 0.0027 17.0 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX90887.1 - 0.0048 16.0 0.0 0.45 9.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFX90887.1 - 0.07 12.4 0.0 15 4.7 0.0 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX90887.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain EHN PF06441.12 KFX90887.1 - 0.1 12.9 0.8 0.52 10.7 0.0 2.4 3 0 0 3 3 3 0 Epoxide hydrolase N terminus HI0933_like PF03486.14 KFX90887.1 - 0.11 11.2 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Rit1_C PF17184.4 KFX90887.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Rit1 N-terminal domain GPS PF01825.21 KFX90887.1 - 4.5 7.9 5.1 1.4 9.5 1.5 1.9 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif SARG PF15385.6 KFX90888.1 - 0.027 13.7 0.5 0.051 12.8 0.5 1.3 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein NMO PF03060.15 KFX90889.1 - 1.3e-12 47.7 1.9 1.7e-12 47.4 1.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KFX90889.1 - 0.003 16.6 3.9 0.004 16.2 3.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFX90889.1 - 0.0094 15.1 0.7 0.014 14.6 0.7 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFX90889.1 - 0.42 9.6 4.3 0.41 9.6 4.3 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NmrA PF05368.13 KFX90890.1 - 4.3e-35 121.4 0.0 5.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX90890.1 - 8.9e-08 32.2 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFX90890.1 - 0.0023 18.2 0.1 0.0035 17.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFX90890.1 - 0.0036 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KFX90891.1 - 3.6e-14 52.7 0.0 7.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KFX90892.1 - 2.8e-34 118.6 32.6 2.8e-34 118.6 32.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily BRCT_2 PF16589.5 KFX90893.1 - 7.9e-06 26.2 0.0 8.1e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFX90893.1 - 0.00049 20.4 0.0 0.0021 18.4 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KFX90893.1 - 0.014 15.5 0.0 8.6 6.5 0.0 2.8 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain adh_short_C2 PF13561.6 KFX90894.1 - 1.7e-49 168.5 6.0 4.7e-49 167.1 6.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX90894.1 - 1.5e-30 106.1 4.8 8.7e-30 103.6 4.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX90894.1 - 2.4e-07 30.9 0.7 5.2e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KFX90894.1 - 0.0079 15.6 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX90894.1 - 0.039 14.2 1.3 0.051 13.8 0.3 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KFX90894.1 - 0.053 13.4 2.7 0.093 12.6 0.6 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KFX90894.1 - 0.055 12.9 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KFX90894.1 - 0.074 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pkinase PF00069.25 KFX90895.1 - 3.2e-14 52.9 0.0 6.4e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90895.1 - 0.006 15.9 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase VWA PF00092.28 KFX90895.1 - 0.012 15.8 0.1 0.046 14.0 0.1 2.0 1 1 1 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.6 KFX90895.1 - 0.15 12.7 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain CorA PF01544.18 KFX90896.1 - 0.0014 18.0 2.4 0.0032 16.9 2.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein GSH_synthase PF03199.15 KFX90896.1 - 0.041 14.3 0.2 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic glutathione synthase DUF3918 PF13056.6 KFX90896.1 - 0.32 10.6 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) T5orf172 PF10544.9 KFX90899.1 - 4.6e-15 56.0 2.3 7.5e-15 55.3 1.2 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 KFX90899.1 - 2.8e-08 34.3 1.7 9.9e-08 32.6 1.1 2.1 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 HATPase_c_3 PF13589.6 KFX90900.1 - 0.00032 20.5 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1347 PF07079.11 KFX90900.1 - 0.047 12.3 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) HTH_33 PF13592.6 KFX90903.1 - 0.12 12.0 0.2 0.26 11.0 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF2527 PF10736.9 KFX90903.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) DEAD_2 PF06733.15 KFX90904.1 - 5.7e-58 195.4 1.1 1.1e-57 194.5 0.2 1.9 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KFX90904.1 - 1.3e-49 168.5 2.7 1.3e-45 155.4 0.8 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KFX90904.1 - 5.8e-43 147.0 0.0 2.1e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KFX90904.1 - 0.00016 21.7 0.7 0.0036 17.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX90904.1 - 0.002 17.9 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFX90904.1 - 0.04 12.6 0.1 0.53 8.9 0.1 2.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 KFX90904.1 - 0.062 13.6 0.4 5.5 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.6 KFX90904.1 - 0.075 12.4 1.3 0.15 11.4 1.3 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFX90904.1 - 0.13 11.7 0.1 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PRP3 PF08572.10 KFX90905.1 - 1.9e-74 250.2 5.1 3e-74 249.5 5.1 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFX90905.1 - 7.7e-49 165.5 1.0 7.7e-49 165.5 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) EPSP_synthase PF00275.20 KFX90906.1 - 3e-129 431.4 0.0 4.4e-129 430.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KFX90906.1 - 4.4e-101 337.4 0.0 9e-101 336.4 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase RNA_pol_Rpb1_5 PF04998.17 KFX90906.1 - 1.8e-87 293.2 0.0 3.2e-87 292.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFX90906.1 - 4.2e-69 232.0 0.1 8.2e-69 231.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 DHquinase_I PF01487.15 KFX90906.1 - 5.5e-55 187.1 0.0 1.3e-54 185.9 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFX90906.1 - 1.1e-36 126.3 0.0 8.9e-35 120.1 0.0 2.8 3 0 0 3 3 3 1 Shikimate kinase RNA_pol_Rpb1_3 PF04983.18 KFX90906.1 - 2.5e-35 121.7 0.0 2.2e-34 118.6 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KFX90906.1 - 2.1e-31 109.5 0.0 6.3e-30 104.6 0.0 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Shikimate_dh_N PF08501.11 KFX90906.1 - 2.8e-23 82.0 0.0 8.3e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain RNA_pol_Rpb1_4 PF05000.17 KFX90906.1 - 2.1e-17 63.0 0.1 8.6e-17 61.0 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Fe-ADH_2 PF13685.6 KFX90906.1 - 2.2e-08 34.1 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KFX90906.1 - 8e-08 31.9 0.0 2.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFX90906.1 - 0.0019 18.3 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase zf-C2H2 PF00096.26 KFX90907.1 - 2e-09 37.4 13.6 0.0032 17.8 1.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX90907.1 - 3.1e-06 27.6 9.2 0.042 14.7 1.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX90907.1 - 0.18 12.3 7.8 9.6 6.8 1.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 KFX90907.1 - 0.25 11.4 1.6 0.71 9.9 1.6 1.8 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 KFX90907.1 - 2 8.8 6.0 2.2 8.7 1.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-T_C PF15511.6 KFX90909.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFX90909.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFX90909.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KFX90909.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFX90909.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KFX90909.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFX90909.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFX90909.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KFX90909.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 KFX90910.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFX90910.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KFX90910.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KFX90910.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFX90910.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFX90910.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF2434 PF10361.9 KFX90911.1 - 0.039 12.9 3.4 2 7.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) Zn_clus PF00172.18 KFX90912.1 - 3.1e-09 36.8 8.0 6.2e-09 35.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX90912.1 - 3.4e-06 26.1 0.0 5.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ctr PF04145.15 KFX90919.1 - 5.3e-15 56.3 0.1 9.5e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Sod_Fe_C PF02777.18 KFX90920.1 - 3e-34 117.3 0.1 6e-34 116.3 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFX90920.1 - 7.9e-32 109.6 3.5 1.5e-31 108.7 3.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ferric_reduct PF01794.19 KFX90921.1 - 2.6e-20 72.8 19.3 2.6e-20 72.8 19.3 2.5 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX90921.1 - 2.3e-13 50.2 0.1 5.4e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX90921.1 - 1.6e-11 44.5 0.0 2.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain TMEM214 PF10151.9 KFX90921.1 - 0.29 9.6 0.4 0.41 9.0 0.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4405 PF14358.6 KFX90921.1 - 4.4 7.9 24.9 0.054 14.0 2.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) Ctr PF04145.15 KFX90922.1 - 6.8e-20 72.2 12.9 2.7e-19 70.3 12.9 1.8 1 1 0 1 1 1 1 Ctr copper transporter family COesterase PF00135.28 KFX90923.1 - 3.8e-86 290.0 0.0 5.8e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX90923.1 - 4e-05 23.6 0.6 0.0026 17.6 0.4 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX90924.1 - 1.5e-60 205.6 0.0 1.5e-27 96.7 0.0 3.0 3 0 0 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX90924.1 - 7.5e-07 29.2 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KFX90924.1 - 0.0042 16.6 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase ABM PF03992.16 KFX90926.1 - 3.5e-05 23.8 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HHH_4 PF14490.6 KFX90926.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Cupin_5 PF06172.11 KFX90927.1 - 2.9e-49 166.8 0.0 3.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) COesterase PF00135.28 KFX90928.1 - 2.9e-77 260.7 0.1 6.7e-71 239.7 0.2 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX90928.1 - 3.9e-09 36.7 0.0 6.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold WTF PF03303.13 KFX90928.1 - 8.9 6.0 12.1 2.6 7.7 7.7 2.2 1 1 1 2 2 2 0 WTF protein Oxidored_FMN PF00724.20 KFX90929.1 - 3.8e-33 115.2 0.0 5.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PdxJ PF03740.13 KFX90929.1 - 0.041 13.0 0.0 0.097 11.8 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ Dus PF01207.17 KFX90929.1 - 0.052 12.6 0.0 0.16 11.0 0.0 1.8 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) HetR_C PF18460.1 KFX90929.1 - 0.056 13.4 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Vps35 PF03635.17 KFX90930.1 - 9.3e-182 606.3 2.6 1.4e-155 519.8 1.1 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 TFIIA PF03153.13 KFX90930.1 - 0.091 12.7 12.7 0.017 15.1 2.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KFX90930.1 - 0.68 9.7 8.0 1.2 8.9 8.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bromodomain PF00439.25 KFX90931.1 - 2.6e-22 78.7 0.4 5e-22 77.8 0.4 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFX90931.1 - 1.8e-08 34.6 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX90931.1 - 2.4e-06 27.5 0.1 5.1e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX90931.1 - 0.00025 21.4 0.1 0.00061 20.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasom_Rpn13 PF04683.13 KFX90933.1 - 3.2e-28 98.1 0.0 5.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KFX90933.1 - 2.8e-13 50.0 0.9 1.1e-11 44.9 0.9 2.3 1 1 0 1 1 1 1 UCH-binding domain SNF5 PF04855.12 KFX90934.1 - 3.9e-94 314.9 0.0 6.7e-94 314.1 0.0 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ribosomal_L6e PF01159.19 KFX90934.1 - 9.8e-39 132.3 0.3 9.8e-39 132.3 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L6e GATA PF00320.27 KFX90934.1 - 3.3e-05 23.4 3.2 7.8e-05 22.2 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KFX90934.1 - 0.013 15.3 4.5 0.14 11.9 0.8 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain cIII PF08134.11 KFX90934.1 - 0.062 13.1 0.1 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 cIII protein family Ribosomal_L7Ae PF01248.26 KFX90935.1 - 7.2e-22 76.9 0.0 8.1e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AFG1_ATPase PF03969.16 KFX90944.1 - 4.5e-98 328.5 0.0 2.6e-93 312.8 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase Hist_deacetyl PF00850.19 KFX90944.1 - 2.4e-53 181.6 0.1 3.9e-53 180.9 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain AAA_16 PF13191.6 KFX90944.1 - 0.0025 18.2 0.0 0.45 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX90944.1 - 0.076 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFX90944.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KFX90944.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KFX90944.1 - 0.18 11.6 0.1 20 4.9 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein YL1 PF05764.13 KFX90944.1 - 0.87 9.7 14.0 2.6 8.1 14.0 1.9 1 0 0 1 1 1 0 YL1 nuclear protein Pkinase PF00069.25 KFX90947.1 - 3.9e-19 69.0 0.0 6.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90947.1 - 1.7e-15 57.0 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_10 PF13673.7 KFX90947.1 - 3.2e-07 30.4 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX90947.1 - 5.4e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX90947.1 - 9.8e-07 29.1 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kdo PF06293.14 KFX90947.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SSP160 PF06933.11 KFX90948.1 - 0.0096 14.2 3.2 0.013 13.7 3.2 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 PAN_4 PF14295.6 KFX90948.1 - 0.016 15.1 0.3 0.05 13.5 0.3 1.9 1 1 0 1 1 1 0 PAN domain Pilin_N PF07790.11 KFX90948.1 - 0.045 14.7 0.0 0.12 13.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Alpha_GJ PF03229.13 KFX90948.1 - 0.07 13.7 6.7 0.14 12.7 6.7 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J TFCD_C PF12612.8 KFX90949.1 - 1.9e-27 96.3 0.0 5e-27 94.9 0.0 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KFX90949.1 - 0.44 11.0 14.8 0.45 10.9 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.6 KFX90949.1 - 0.66 10.4 13.4 0.76 10.2 0.4 5.4 6 0 0 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 KFX90949.1 - 2.5 8.7 5.4 4.8 7.8 0.1 4.5 5 0 0 5 5 5 0 HEAT-like repeat SWIM PF04434.17 KFX90950.1 - 0.14 11.8 0.4 0.33 10.7 0.4 1.5 1 0 0 1 1 1 0 SWIM zinc finger AA_permease_2 PF13520.6 KFX90951.1 - 3e-42 145.0 40.7 1.1e-41 143.1 40.7 1.8 1 1 0 1 1 1 1 Amino acid permease Nitroreductase PF00881.24 KFX90951.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Nitroreductase family ABC_tran PF00005.27 KFX90952.1 - 1.2e-46 158.6 0.1 1.4e-24 87.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFX90952.1 - 4.1e-24 85.9 3.3 9.8e-06 25.6 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFX90952.1 - 1.4e-18 67.1 47.7 2.7e-13 49.7 23.0 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KFX90952.1 - 5.8e-09 35.6 1.5 0.00016 21.3 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFX90952.1 - 4.6e-08 32.8 2.6 0.1 12.0 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX90952.1 - 2.4e-07 31.5 2.2 0.016 15.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFX90952.1 - 3e-05 23.9 0.2 0.13 12.0 0.4 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX90952.1 - 5.9e-05 23.0 0.9 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 KFX90952.1 - 0.00011 21.9 0.9 0.26 10.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 KFX90952.1 - 0.00049 20.8 0.0 0.003 18.2 0.0 2.4 3 0 0 3 3 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KFX90952.1 - 0.0015 19.0 1.3 1.4 9.3 0.5 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFX90952.1 - 0.0061 15.9 0.3 6.7 5.9 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin Ploopntkinase1 PF18748.1 KFX90952.1 - 0.0062 16.1 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 AAA_30 PF13604.6 KFX90952.1 - 0.0072 16.1 3.8 1.9 8.2 0.9 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFX90952.1 - 0.032 14.5 0.2 5 7.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFX90952.1 - 0.049 13.4 0.0 9.4 5.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein MukB PF04310.12 KFX90952.1 - 0.069 12.9 0.2 10 5.9 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 KFX90952.1 - 0.07 12.7 0.4 11 5.5 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KFX90952.1 - 0.08 13.2 1.5 3 8.1 0.7 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KFX90952.1 - 0.093 13.0 0.4 30 5.0 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 KFX90952.1 - 0.12 12.7 0.1 5.2 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFX90952.1 - 1.6 8.0 6.1 24 4.3 0.5 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NAD_binding_10 PF13460.6 KFX90953.1 - 1.2e-34 119.9 0.0 1.3e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX90953.1 - 9.1e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFX90953.1 - 0.00011 21.7 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAC2 PF09754.9 KFX90953.1 - 0.019 15.0 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 PAC2 family RmlD_sub_bind PF04321.17 KFX90953.1 - 0.12 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TraD PF06412.11 KFX90953.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TraD RRM_1 PF00076.22 KFX90960.1 - 3e-15 55.8 0.0 5.8e-12 45.3 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 KFX90960.1 - 0.0028 17.5 0.1 0.0089 15.9 0.1 1.9 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain RRM_occluded PF16842.5 KFX90960.1 - 0.094 12.6 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Cpn60_TCP1 PF00118.24 KFX90964.1 - 3.9e-148 494.1 7.4 4.4e-148 494.0 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 KFX90964.1 - 0.015 15.3 0.1 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain DUF4334 PF14232.6 KFX90965.1 - 0.021 14.8 0.0 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) Glyco_hydro_61 PF03443.14 KFX90966.1 - 1.1e-43 149.6 0.0 1.5e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.17 KFX90967.1 - 1.2e-105 353.7 1.7 1.5e-105 353.3 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KFX90967.1 - 2.8e-12 46.4 12.8 2.8e-12 46.4 12.8 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX90967.1 - 2.2 8.6 10.2 0.062 13.6 2.4 2.5 3 0 0 3 3 3 0 Toxin 7 Glyco_hydro_61 PF03443.14 KFX90968.1 - 5.9e-50 170.1 0.0 7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KFX90969.1 - 3.3e-62 210.1 0.2 4.2e-62 209.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDH-cyt PF16010.5 KFX90970.1 - 7e-59 198.6 0.9 2.7e-58 196.7 0.2 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KFX90970.1 - 4.9e-27 95.1 0.1 9.6e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX90970.1 - 1.2e-22 80.9 0.2 2.3e-22 80.1 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX90970.1 - 1.1e-08 34.6 0.4 0.004 16.3 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX90970.1 - 0.0013 18.0 0.7 0.0086 15.3 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX90970.1 - 0.0025 18.0 0.1 0.01 16.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX90970.1 - 0.0042 16.7 0.6 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX90970.1 - 0.0093 15.4 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX90970.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KFX90970.1 - 0.035 14.7 0.2 0.092 13.3 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX90970.1 - 0.069 12.4 0.2 0.19 10.9 0.2 1.7 1 0 0 1 1 1 0 Thi4 family RNHCP PF12647.7 KFX90970.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 RNHCP domain GIDA PF01134.22 KFX90970.1 - 0.86 8.6 3.5 1.1 8.3 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Beta-lactamase PF00144.24 KFX90972.1 - 3.4e-41 141.6 0.0 4.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX90972.1 - 0.068 12.6 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SMI1_KNR4 PF09346.10 KFX90973.1 - 0.0031 17.9 0.0 0.0066 16.8 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Prismane PF03063.20 KFX90973.1 - 0.055 12.2 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Iwr1 PF08574.10 KFX90974.1 - 9.9e-13 48.9 8.8 9.9e-13 48.9 8.8 3.3 2 1 1 3 3 3 2 Transcription factor Iwr1 DUF4598 PF15370.6 KFX90974.1 - 0.27 11.7 7.2 1.6 9.2 7.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) Chromo_shadow PF01393.19 KFX90975.1 - 0.037 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain GST_N_3 PF13417.6 KFX90979.1 - 1.8e-09 37.9 0.1 7e-09 36.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX90979.1 - 2.2e-09 37.5 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX90979.1 - 4.9e-06 26.5 0.1 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KFX90979.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_C_3 PF14497.6 KFX90979.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX90979.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box PF00646.33 KFX90989.1 - 6.3e-07 29.1 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX90989.1 - 5.3e-06 26.2 0.1 1.5e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFX90989.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 KFX90991.1 - 4.5e-07 30.0 13.3 0.029 14.8 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX90991.1 - 0.00037 20.8 9.9 0.44 11.1 0.2 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX90991.1 - 0.002 18.8 11.9 0.042 14.7 1.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFX90991.1 - 0.02 15.2 6.7 0.11 12.8 0.8 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FPN1 PF06963.12 KFX90992.1 - 1.3e-94 317.3 9.8 1.6e-94 317.0 9.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Aha1_N PF09229.11 KFX90993.1 - 1.3e-39 135.5 0.1 2.1e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KFX90993.1 - 5.1e-20 72.0 1.2 6.1e-20 71.7 0.4 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein p450 PF00067.22 KFX90995.1 - 6.6e-61 206.5 0.0 8.9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KFX90996.1 - 3.1e-75 253.8 33.4 3.5e-75 253.6 33.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90996.1 - 7.8e-21 74.4 37.4 7.8e-21 74.4 37.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX90996.1 - 0.18 10.1 10.0 0.63 8.2 3.7 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_12 PF13424.6 KFX90997.1 - 3.5e-82 270.7 23.6 5.1e-18 65.1 0.7 5.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KFX90997.1 - 2.6e-69 227.4 5.8 4.8e-11 42.1 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90997.1 - 4.6e-16 57.9 8.9 0.011 15.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90997.1 - 2e-14 52.5 2.4 0.0012 18.7 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90997.1 - 1.8e-12 46.3 8.2 0.2 11.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX90997.1 - 1e-11 44.6 2.4 0.025 15.4 0.0 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX90997.1 - 2.3e-10 40.9 0.0 0.00013 22.5 0.0 5.5 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90997.1 - 4.4e-09 35.9 5.9 0.91 9.9 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFX90997.1 - 1.5e-08 34.5 0.3 0.1 13.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX90997.1 - 3e-08 33.5 1.6 18 6.0 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90997.1 - 8.4e-08 32.3 0.2 0.0065 16.7 0.0 4.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 KFX90997.1 - 1.6e-07 30.8 0.0 0.0079 15.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_MalT PF17874.1 KFX90997.1 - 3.6e-07 29.9 7.5 2.7e-06 27.0 2.6 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KFX90997.1 - 2.9e-06 27.7 3.0 0.27 11.7 0.1 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat AAA_16 PF13191.6 KFX90997.1 - 0.0013 19.2 0.4 0.0058 17.0 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX90997.1 - 0.0013 19.0 0.0 0.038 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.6 KFX90997.1 - 0.033 13.9 3.5 30 4.4 0.0 4.7 5 0 0 5 5 5 0 TPR repeat DUF676 PF05057.14 KFX90997.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Atu4866 PF11512.8 KFX90997.1 - 0.18 12.2 2.2 1.1e+02 3.3 0.1 3.9 3 1 1 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 DUF3856 PF12968.7 KFX90997.1 - 0.48 10.5 3.2 66 3.6 0.0 3.5 1 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 KFX90997.1 - 7 7.1 8.8 69 4.0 0.1 5.0 5 0 0 5 5 5 0 PPR repeat DUF3726 PF12525.8 KFX90997.1 - 8.3 6.6 6.0 90 3.3 0.1 4.4 5 0 0 5 5 4 0 Protein of unknown function (DUF3726) TPR_3 PF07720.12 KFX90997.1 - 9.7 6.3 6.0 9.2 6.4 0.0 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat APH PF01636.23 KFX90998.1 - 3e-38 132.1 0.0 8.1e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF86 PF01934.17 KFX90998.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 AA_permease_2 PF13520.6 KFX91001.1 - 1.6e-55 188.7 27.3 2e-55 188.4 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX91001.1 - 1.7e-22 79.7 23.0 2.5e-22 79.1 23.0 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_90 PF05686.12 KFX91002.1 - 4.2e-14 52.3 3.7 2.9e-09 36.3 1.7 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 CadC_C1 PF18500.1 KFX91002.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 CadC C-terminal domain 1 DUF5560 PF17715.1 KFX91002.1 - 0.11 11.9 0.6 0.25 10.8 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5560) DNA_pol_A PF00476.20 KFX91002.1 - 0.24 10.4 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family A Ribosomal_L7Ae PF01248.26 KFX91003.1 - 8.6e-28 95.9 1.0 1.1e-27 95.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KFX91003.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain OPT PF03169.15 KFX91004.1 - 1.5e-91 308.0 43.8 1.7e-91 307.8 43.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nucleos_tra2_N PF01773.20 KFX91004.1 - 6 7.5 10.5 0.56 10.8 3.4 3.0 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Beta-lactamase PF00144.24 KFX91005.1 - 5.9e-36 124.4 0.1 1.1e-35 123.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_106 PF17132.4 KFX91005.1 - 3.3e-29 101.7 0.1 4.7e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 alpha-L-rhamnosidase LRR_4 PF12799.7 KFX91006.1 - 1.3e-35 120.8 53.0 5.7e-08 32.9 3.3 10.1 8 3 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX91006.1 - 1.9e-33 114.0 55.0 5e-08 32.6 6.1 9.3 4 2 6 10 10 10 10 Leucine rich repeat LRR_1 PF00560.33 KFX91006.1 - 2.4e-09 36.4 45.5 0.69 10.7 0.2 13.7 14 3 0 14 14 14 3 Leucine Rich Repeat LRR_6 PF13516.6 KFX91006.1 - 8.4e-05 22.3 36.9 4.4 7.6 0.7 11.1 12 0 0 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.6 KFX91006.1 - 0.0003 20.3 22.6 0.38 10.3 3.3 5.0 2 2 2 5 5 5 4 Leucine-rich repeat LRR_2 PF07723.13 KFX91006.1 - 0.34 11.6 9.6 2.5 8.9 0.5 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat UCR_hinge PF02320.16 KFX91008.1 - 1.2e-26 92.6 8.8 1.2e-26 92.6 8.8 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein RR_TM4-6 PF06459.12 KFX91008.1 - 0.43 10.4 9.1 0.45 10.3 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myc_N PF01056.18 KFX91008.1 - 0.94 9.3 11.8 1.1 9.1 11.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region VIT1 PF01988.19 KFX91008.1 - 1.2 9.0 4.1 1.3 8.9 4.1 1.1 1 0 0 1 1 1 0 VIT family YqfQ PF14181.6 KFX91008.1 - 1.9 8.7 6.5 2 8.6 6.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Pox_Ag35 PF03286.14 KFX91008.1 - 1.9 8.3 11.2 2.4 7.9 11.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.8 KFX91008.1 - 4.5 6.0 9.4 4.7 5.9 9.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Merozoite_SPAM PF07133.11 KFX91008.1 - 5.1 7.1 25.3 6.9 6.6 25.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 KFX91008.1 - 5.9 5.5 6.9 6.7 5.4 6.9 1.0 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 KFX91008.1 - 7.8 5.8 15.0 8.7 5.7 15.0 1.1 1 0 0 1 1 1 0 SDA1 Lipase_GDSL_2 PF13472.6 KFX91009.1 - 1.1e-12 48.7 0.7 1.3e-12 48.5 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX91009.1 - 4.7e-05 23.4 0.2 7.1e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.19 KFX91010.1 - 4.5e-81 272.9 5.8 8.2e-81 272.1 5.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFX91010.1 - 2.3e-56 189.3 0.6 5.5e-31 107.5 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KFX91010.1 - 6.9e-54 182.4 6.3 1.3e-53 181.5 6.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KFX91010.1 - 1.7e-25 88.4 0.4 1.8e-24 85.1 0.7 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pyr_redox_2 PF07992.14 KFX91011.1 - 1.9e-30 106.1 0.0 2.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX91011.1 - 8.1e-10 39.1 0.2 4.4e-07 30.4 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX91011.1 - 5.6e-05 23.2 1.4 0.18 11.8 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX91011.1 - 0.00076 18.7 0.0 0.0048 16.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX91011.1 - 0.0012 18.1 0.0 0.005 16.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4232 PF14016.6 KFX91011.1 - 0.028 14.5 1.4 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Trp_halogenase PF04820.14 KFX91011.1 - 0.043 12.7 0.4 6.2 5.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 KFX91011.1 - 0.056 13.0 2.9 26 4.3 0.1 3.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase Abhydrolase_1 PF00561.20 KFX91011.1 - 0.12 12.0 0.4 0.25 10.9 0.4 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KFX91012.1 - 1.4e-27 96.6 52.6 2.8e-15 56.1 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1072 PF06380.11 KFX91012.1 - 1.5 8.8 8.4 5.9 6.9 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Cutinase PF01083.22 KFX91013.1 - 4.9e-49 166.7 2.7 6.2e-49 166.4 2.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFX91013.1 - 0.0048 16.5 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KFX91013.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) adh_short PF00106.25 KFX91016.1 - 2.8e-24 85.7 3.4 2.5e-21 76.0 2.8 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91016.1 - 5.4e-13 49.1 3.7 1.3e-10 41.2 3.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91016.1 - 6.5e-11 42.5 1.8 9.9e-11 41.9 1.8 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KFX91017.1 - 3.5e-05 22.8 0.1 0.0002 20.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MGC-24 PF05283.11 KFX91018.1 - 0.023 15.1 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Abhydrolase_2 PF02230.16 KFX91019.1 - 1.7e-23 83.6 0.0 1.6e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase ArdA PF07275.11 KFX91019.1 - 0.0098 16.5 0.0 0.057 14.0 0.1 2.1 2 0 0 2 2 2 1 Antirestriction protein (ArdA) Abhydrolase_6 PF12697.7 KFX91019.1 - 0.024 15.2 0.7 0.054 14.1 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Gpi1 PF05024.15 KFX91027.1 - 4.3e-77 258.4 9.3 4.3e-77 258.4 9.3 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 KFX91027.1 - 0.038 13.3 0.6 0.097 12.0 0.6 1.6 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) UPF0203 PF05254.12 KFX91028.1 - 5.6e-27 93.8 0.6 6.4e-27 93.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KFX91028.1 - 8.6e-05 22.8 0.1 0.00018 21.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KFX91028.1 - 0.00095 19.1 1.9 0.041 13.9 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KFX91028.1 - 0.035 13.8 0.9 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 KFX91028.1 - 0.1 12.8 2.4 0.84 9.9 2.4 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.8 KFX91028.1 - 0.12 12.7 1.4 0.56 10.6 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) DNA_pol_A_exo1 PF01612.20 KFX91029.1 - 1e-38 132.8 0.1 1.4e-38 132.3 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFX91029.1 - 1.9e-28 99.0 0.1 5.8e-28 97.4 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFX91029.1 - 9e-14 51.2 0.0 3.3e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 HRDC domain DUF2833 PF11090.8 KFX91029.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) RasGAP PF00616.19 KFX91030.1 - 9e-60 201.9 0.0 2.5e-59 200.5 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFX91030.1 - 1.1e-28 100.1 2.5 1.1e-28 100.1 2.5 2.5 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 KFX91030.1 - 0.078 12.9 0.0 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 MarR family DUF948 PF06103.11 KFX91030.1 - 0.18 12.1 0.7 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fmp27_WPPW PF10359.9 KFX91030.1 - 2.6 6.8 6.8 4.8 5.9 0.6 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain KLRAQ PF10205.9 KFX91030.1 - 4.5 7.6 10.6 22 5.3 0.4 3.9 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein Cpn60_TCP1 PF00118.24 KFX91038.1 - 5.5e-170 566.2 1.3 6.2e-170 566.0 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KFX91038.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 BRK domain SH3_3 PF08239.11 KFX91040.1 - 0.036 14.4 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Chlorosome_CsmC PF11098.8 KFX91043.1 - 0.11 12.5 9.1 0.18 11.8 9.1 1.5 1 1 0 1 1 1 0 Chlorosome envelope protein C CaM_bdg_C0 PF10562.9 KFX91048.1 - 0.54 10.3 6.6 1.4 9.0 6.6 1.7 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF4449 PF14613.6 KFX91049.1 - 3.9e-66 222.2 1.7 3.9e-66 222.2 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 KFX91049.1 - 0.15 12.1 1.5 3.3 7.7 0.0 2.8 1 1 1 2 2 2 0 Prp18 domain RasGEF PF00617.19 KFX91050.1 - 3.9e-59 199.8 0.0 6.8e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFX91050.1 - 1.5e-27 95.9 0.3 3.5e-27 94.7 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFX91050.1 - 2.6e-15 55.7 0.1 5.9e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain DUF4238 PF14022.6 KFX91050.1 - 1.4e-14 54.3 0.2 3.5e-14 53.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) SH3_9 PF14604.6 KFX91050.1 - 5.4e-14 51.8 0.4 1.4e-13 50.5 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KFX91050.1 - 1.8e-13 50.0 0.1 9.4e-13 47.6 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 KFX91050.1 - 0.00012 22.1 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 WW domain DUF5333 PF17267.2 KFX91050.1 - 0.023 14.9 0.1 0.83 9.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5333) SQS_PSY PF00494.19 KFX91050.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF726 PF05277.12 KFX91053.1 - 2.9e-126 421.1 3.1 4e-126 420.6 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) UPF0565 PF10561.9 KFX91053.1 - 0.068 12.4 0.0 0.26 10.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Pkinase PF00069.25 KFX91054.1 - 3e-16 59.6 0.0 1.6e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91054.1 - 4.8e-13 49.0 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX91054.1 - 0.025 13.9 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFX91054.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.27 KFX91055.1 - 2e-48 164.4 0.1 7.8e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFX91055.1 - 2.1e-23 83.0 43.0 1.3e-16 60.7 10.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFX91055.1 - 7.8e-20 71.9 0.9 4e-05 23.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX91055.1 - 1.1e-07 31.5 2.0 2.8e-05 23.7 0.0 3.6 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFX91055.1 - 1.5e-06 28.2 0.2 0.76 9.4 0.0 3.3 3 0 0 3 3 3 3 AAA ATPase domain AAA_23 PF13476.6 KFX91055.1 - 5.8e-06 26.9 4.6 0.018 15.6 0.2 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KFX91055.1 - 2.2e-05 24.1 1.0 0.22 11.3 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX91055.1 - 3.3e-05 23.7 1.2 0.099 12.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFX91055.1 - 0.00023 21.5 1.6 0.23 11.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX91055.1 - 0.00036 20.5 0.3 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFX91055.1 - 0.0035 17.7 0.1 3 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KFX91055.1 - 0.012 16.0 0.3 3.7 8.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFX91055.1 - 0.013 15.9 0.0 1 9.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KFX91055.1 - 0.018 14.9 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 KFX91055.1 - 0.035 13.9 0.5 5.6 6.7 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KFX91055.1 - 0.036 14.3 0.8 12 6.2 0.2 3.3 2 2 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KFX91055.1 - 0.051 13.3 0.6 61 3.3 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein MukB PF04310.12 KFX91055.1 - 0.055 13.3 0.7 7.9 6.2 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 KFX91055.1 - 0.079 12.2 0.1 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KFX91055.1 - 0.21 11.2 4.4 1.7 8.3 0.3 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KFX91055.1 - 0.24 11.7 1.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MIP PF00230.20 KFX91056.1 - 1.1e-28 100.6 8.6 1.9e-28 99.7 8.6 1.4 1 1 0 1 1 1 1 Major intrinsic protein DDDD PF10161.9 KFX91056.1 - 0.11 12.2 0.3 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Glyco_hydro_30 PF02055.16 KFX91057.1 - 1.6e-19 70.1 0.4 2.1e-19 69.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KFX91057.1 - 1.8e-06 28.1 1.2 3.5e-06 27.1 1.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFX91057.1 - 0.002 17.4 1.2 0.0043 16.3 1.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KFX91057.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Tube PF17212.3 KFX91057.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Tail tubular protein Glyco_hydro_76 PF03663.14 KFX91058.1 - 1.6e-150 501.7 17.3 1.9e-150 501.5 17.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX91058.1 - 0.0073 15.4 9.2 0.67 9.0 1.1 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 zf-C2H2_4 PF13894.6 KFX91061.1 - 0.033 15.0 0.9 0.08 13.8 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KFX91061.1 - 0.057 13.7 0.1 0.097 13.0 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 KFX91061.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 KFX91061.1 - 0.21 12.1 0.7 1.8 9.2 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pneumo_att_G PF05539.11 KFX91061.1 - 3 7.4 6.5 3.7 7.0 6.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-C2H2_2 PF12756.7 KFX91062.1 - 2.2e-32 111.4 7.7 1.4e-26 92.8 0.5 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFX91062.1 - 1.7e-07 31.4 7.5 0.016 15.5 1.3 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX91062.1 - 0.0035 17.7 1.6 0.0035 17.7 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFX91062.1 - 0.017 15.9 13.3 4.9 8.3 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX91062.1 - 0.081 13.4 0.4 0.081 13.4 0.4 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 KFX91062.1 - 0.34 11.1 4.7 1.5 9.0 0.3 3.1 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF4820 PF16091.5 KFX91062.1 - 2.1 7.6 7.9 34 3.7 5.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) HECT PF00632.25 KFX91063.1 - 5.1e-65 220.0 0.0 7.8e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.16 KFX91063.1 - 1.8e-35 122.5 27.4 1.8e-35 122.5 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AZUL PF16558.5 KFX91063.1 - 3.6e-19 68.8 2.4 7.4e-19 67.7 2.4 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Sugar_tr PF00083.24 KFX91063.1 - 1.3e-08 34.2 7.5 1.3e-08 34.2 7.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFX91063.1 - 0.00026 19.6 3.1 0.00042 18.9 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4576 PF15144.6 KFX91063.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Asp PF00026.23 KFX91066.1 - 8.7e-71 238.9 8.3 1e-70 238.7 8.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX91066.1 - 1.4e-11 44.9 6.0 5.3e-05 23.5 1.8 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX91066.1 - 0.00028 21.5 3.7 0.0099 16.5 1.4 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX91066.1 - 0.038 14.5 0.7 0.26 11.9 0.1 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF2373 PF10180.9 KFX91071.1 - 1.4e-21 76.1 0.2 3.9e-21 74.7 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Methyltransf_1N PF02870.15 KFX91071.1 - 0.093 13.5 0.2 1.2 10.0 0.1 2.7 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Proteasome PF00227.26 KFX91072.1 - 2.7e-49 167.3 0.0 3.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX91072.1 - 4.9e-13 48.5 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 KFX91072.1 - 0.037 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family PIG-L PF02585.17 KFX91073.1 - 0.034 14.8 0.0 0.043 14.4 0.0 1.2 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Glyco_hydro_18 PF00704.28 KFX91074.1 - 1.6e-51 175.9 4.6 1.6e-51 175.9 4.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX91074.1 - 1.8e-19 69.9 100.4 7.9e-08 32.6 13.1 4.7 4 0 0 4 4 4 4 Chitin recognition protein Cutinase PF01083.22 KFX91076.1 - 0.00035 20.6 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 Cutinase Palm_thioest PF02089.15 KFX91076.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFX91076.1 - 0.0025 17.6 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX91076.1 - 0.0033 18.1 0.0 0.0049 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FYVE PF01363.21 KFX91076.1 - 0.0041 17.2 15.3 0.012 15.8 5.1 2.4 2 0 0 2 2 2 2 FYVE zinc finger DUF676 PF05057.14 KFX91076.1 - 0.043 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF726 PF05277.12 KFX91076.1 - 0.048 12.6 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 KFX91076.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 KFX91076.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Aurora-A_bind PF09041.10 KFX91076.1 - 0.15 12.1 0.2 0.42 10.7 0.2 1.7 1 0 0 1 1 1 0 Aurora-A binding zinc-ribbons_6 PF07191.12 KFX91076.1 - 0.23 11.5 16.8 0.27 11.2 4.5 2.3 2 0 0 2 2 2 0 zinc-ribbons Fumarate_red_C PF02300.17 KFX91077.1 - 0.062 13.4 0.3 0.082 13.0 0.3 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit C Ribosomal_L22 PF00237.19 KFX91083.1 - 5.9e-29 100.3 0.1 1e-28 99.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RRM_1 PF00076.22 KFX91084.1 - 2.2e-46 155.6 0.0 4.5e-14 52.0 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX91084.1 - 9.6e-37 124.7 0.1 6.1e-28 96.5 0.0 4.5 4 1 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFX91084.1 - 1.1e-05 25.3 0.0 0.24 11.4 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KFX91084.1 - 0.00012 21.7 0.0 0.11 12.0 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KFX91084.1 - 0.0021 17.9 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 RL domain RRM_3 PF08777.11 KFX91084.1 - 0.073 13.1 2.1 0.36 10.9 0.1 3.1 4 0 0 4 4 4 0 RNA binding motif TPR_14 PF13428.6 KFX91084.1 - 0.58 11.1 12.6 8.9 7.4 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_M43 PF05572.13 KFX91085.1 - 2.2e-12 47.1 0.0 3.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KFX91085.1 - 3.2e-06 27.7 0.0 6.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFX91085.1 - 0.0027 17.9 0.5 0.35 11.0 0.1 2.4 2 0 0 2 2 2 2 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFX91085.1 - 0.018 14.7 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFX91085.1 - 0.2 11.5 0.2 0.49 10.2 0.2 1.4 1 1 0 1 1 1 0 Matrixin MFS_MOT1 PF16983.5 KFX91086.1 - 5.5e-64 213.5 28.6 8.1e-35 119.6 10.3 2.4 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KFX91086.1 - 2.4e-05 23.3 5.5 2.4e-05 23.3 5.5 2.7 1 1 0 2 2 2 2 Sulfate permease family SPC12 PF06645.13 KFX91086.1 - 4.3 7.5 10.4 0.18 11.9 0.5 3.4 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MRC1 PF09444.10 KFX91087.1 - 1.6e-43 148.7 22.0 1.6e-43 148.7 22.0 9.2 6 2 1 8 8 8 1 MRC1-like domain BUD22 PF09073.10 KFX91087.1 - 0.001 18.5 21.9 0.001 18.5 21.9 5.8 3 2 1 4 4 4 1 BUD22 RabGAP-TBC PF00566.18 KFX91088.1 - 3e-49 167.6 0.0 6.6e-49 166.5 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 KFX91089.1 - 1.1e-32 111.7 0.2 5.9e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX91089.1 - 1.2e-10 41.4 0.2 0.00033 20.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFX91089.1 - 0.0068 16.4 0.1 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFX91089.1 - 0.07 13.1 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GEMIN8 PF15348.6 KFX91089.1 - 0.16 12.2 5.1 0.43 10.8 5.1 1.7 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 UTP15_C PF09384.10 KFX91090.1 - 5.2e-53 178.7 0.0 8.9e-53 177.9 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFX91090.1 - 7.1e-20 71.0 1.2 0.00027 21.6 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91090.1 - 7.6e-07 29.3 0.3 0.26 11.6 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KFX91090.1 - 0.061 13.3 0.0 5.2 7.1 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Nup160 PF11715.8 KFX91090.1 - 0.071 11.7 0.1 8.2 4.9 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 HA2 PF04408.23 KFX91091.1 - 3.6e-20 72.2 0.1 3.6e-20 72.2 0.1 3.8 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX91091.1 - 3.5e-19 69.0 0.0 7.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX91091.1 - 2.6e-14 53.5 0.0 8.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFX91091.1 - 1.8e-05 25.0 0.0 5.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX91091.1 - 2.7e-05 24.0 0.0 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFX91091.1 - 0.00058 19.6 0.1 0.00058 19.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFX91091.1 - 0.0024 17.0 0.0 0.0055 15.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFX91091.1 - 0.022 15.1 0.1 0.056 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFX91091.1 - 0.022 14.4 0.1 0.051 13.2 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KFX91091.1 - 0.05 14.1 1.4 0.15 12.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFX91091.1 - 0.22 12.0 0.1 0.22 12.0 0.1 3.5 1 1 1 2 2 1 0 AAA domain AAA_14 PF13173.6 KFX91091.1 - 0.37 10.8 1.6 2.8 8.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 KFX91092.1 - 1.6e-28 99.7 0.0 2.5e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFX91092.1 - 5.1e-25 87.4 0.9 8.1e-25 86.7 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX91092.1 - 1.2e-14 54.4 13.7 2.1e-14 53.6 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFX91092.1 - 0.00012 21.9 3.4 0.063 13.2 0.5 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFX91092.1 - 0.0061 16.6 6.4 0.37 10.8 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KFX91092.1 - 2.9 8.3 6.9 3.6 8.1 1.4 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar adh_short PF00106.25 KFX91095.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX91095.1 - 0.0046 16.9 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX91095.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3425 PF11905.8 KFX91096.1 - 7.3e-18 64.7 0.1 2.1e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Cwf_Cwc_15 PF04889.12 KFX91096.1 - 0.075 12.8 2.2 0.1 12.3 2.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP PF00188.26 KFX91097.1 - 4.5e-10 40.4 1.7 5.5e-10 40.2 1.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CBM_19 PF03427.13 KFX91097.1 - 0.075 13.0 1.3 0.14 12.2 1.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) MFS_1 PF07690.16 KFX91100.1 - 7.8e-36 123.7 28.0 7.8e-36 123.7 28.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX91100.1 - 6.5e-05 21.5 3.9 0.00012 20.6 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA PF00004.29 KFX91101.1 - 2e-19 70.3 0.0 2.2e-17 63.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX91101.1 - 2.1e-08 34.3 0.0 3.7e-05 23.7 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KFX91101.1 - 6.1e-08 33.0 0.0 0.0019 18.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFX91101.1 - 4.4e-07 30.4 0.2 0.09 13.1 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KFX91101.1 - 8.6e-06 26.3 0.0 0.041 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFX91101.1 - 8.1e-05 23.0 0.1 0.13 12.7 0.1 2.9 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KFX91101.1 - 0.00015 21.5 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX91101.1 - 0.00053 19.7 0.6 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 KFX91101.1 - 0.0011 18.2 0.1 0.59 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_14 PF13173.6 KFX91101.1 - 0.0013 18.8 0.1 4.5 7.3 0.0 3.3 2 1 1 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KFX91101.1 - 0.0099 15.2 0.0 3.8 6.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 KFX91101.1 - 0.0099 16.4 0.0 0.14 12.7 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.14 KFX91101.1 - 0.011 15.8 0.0 0.28 11.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SesA PF17107.5 KFX91101.1 - 0.012 15.8 0.1 0.058 13.6 0.1 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NTPase_1 PF03266.15 KFX91101.1 - 0.014 15.3 0.0 4.7 7.1 0.0 2.9 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 KFX91101.1 - 0.016 15.2 0.0 0.076 12.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KFX91101.1 - 0.019 15.4 0.2 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFX91101.1 - 0.021 14.2 2.4 0.56 9.5 0.3 2.7 3 0 0 3 3 3 0 KaiC TsaE PF02367.17 KFX91101.1 - 0.023 14.7 0.0 11 6.0 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KFX91101.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KFX91101.1 - 0.031 14.6 0.0 14 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KFX91101.1 - 0.032 14.3 3.8 1.7 8.7 0.0 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KFX91101.1 - 0.054 13.2 0.2 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFX91101.1 - 0.064 13.2 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF2075 PF09848.9 KFX91101.1 - 0.085 12.1 0.0 8.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KFX91101.1 - 0.087 13.0 0.2 14 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFX91101.1 - 0.11 12.0 0.0 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KFX91101.1 - 0.61 10.5 3.9 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4472 PF14739.6 KFX91101.1 - 0.63 10.8 3.2 2.1 9.1 3.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) SUI1 PF01253.22 KFX91104.1 - 1.5e-27 95.9 3.9 1.5e-27 95.9 3.9 1.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 UPF0139 PF03669.13 KFX91105.1 - 7.6e-05 22.5 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Glyco_hydro_72 PF03198.14 KFX91115.1 - 6.9e-122 406.6 1.8 8.5e-122 406.3 1.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KFX91115.1 - 5.7e-07 28.9 0.4 2.5e-06 26.8 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ribosomal_S7e PF01251.18 KFX91116.1 - 8.1e-81 270.2 0.1 9.5e-81 270.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e V_ATPase_I PF01496.19 KFX91122.1 - 0 1062.0 0.0 0 1061.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prenyltransf PF01255.19 KFX91122.1 - 6.5e-79 264.6 0.0 2.2e-78 262.9 0.0 1.8 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Filament PF00038.21 KFX91122.1 - 0.045 13.3 4.4 2.9 7.4 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.15 KFX91122.1 - 0.067 13.0 0.2 0.45 10.3 0.2 2.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.10 KFX91122.1 - 0.08 12.8 0.5 15 5.5 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4988 PF16378.5 KFX91122.1 - 0.14 11.8 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function Baculo_PEP_C PF04513.12 KFX91122.1 - 0.3 11.1 1.3 4.8 7.2 0.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 KFX91122.1 - 0.37 10.2 1.9 2 7.8 0.1 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KFX91122.1 - 1.5 8.9 4.1 1.9 8.5 0.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 KFX91122.1 - 3.1 7.5 4.0 1.9 8.2 1.1 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Atg14 PF10186.9 KFX91122.1 - 6.1 5.8 5.8 0.75 8.8 0.9 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NmrA PF05368.13 KFX91125.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Nucleos_tra2_C PF07662.13 KFX91126.1 - 3.4e-71 239.4 1.3 4.7e-71 238.9 1.3 1.2 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus ATP1G1_PLM_MAT8 PF02038.16 KFX91126.1 - 0.1 12.1 1.4 0.28 10.6 1.4 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Thr_synth_N PF14821.6 KFX91126.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonine synthase N terminus DUF2569 PF10754.9 KFX91126.1 - 1.2 9.6 5.8 5 7.6 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) GerPC PF10737.9 KFX91133.1 - 0.0015 18.6 4.6 0.0023 18.0 4.6 1.3 1 0 0 1 1 1 1 Spore germination protein GerPC Cas_DxTHG PF09455.10 KFX91133.1 - 0.044 13.4 2.9 0.053 13.1 2.9 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family CsiD PF08943.10 KFX91133.1 - 0.081 12.0 2.3 0.2 10.7 1.4 1.9 2 0 0 2 2 2 0 CsiD Enterotoxin_ST PF02048.16 KFX91133.1 - 0.48 10.9 8.8 0.2 12.1 4.3 2.7 2 1 1 3 3 3 0 Heat-stable enterotoxin ST DUF668 PF05003.12 KFX91133.1 - 0.61 10.6 4.8 77 3.9 4.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF668) DUF1456 PF07308.13 KFX91133.1 - 3.3 8.1 6.8 0.63 10.4 2.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Myb_DNA-binding PF00249.31 KFX91134.1 - 6.6e-10 39.0 0.1 1.6e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 KFX91134.1 - 2e-08 33.9 7.2 3.6e-08 33.1 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KFX91134.1 - 3.8e-07 30.4 0.0 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain CDP-OH_P_transf PF01066.21 KFX91135.1 - 4.2e-12 46.7 0.6 4.2e-12 46.7 0.6 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short PF00106.25 KFX91136.1 - 4.3e-31 107.9 0.3 2.6e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91136.1 - 2.4e-21 76.4 0.2 4.1e-13 49.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91136.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PRANC PF09372.10 KFX91136.1 - 0.03 14.7 0.0 0.083 13.2 0.0 1.7 2 0 0 2 2 2 0 PRANC domain Pyr_redox_2 PF07992.14 KFX91137.1 - 8.3e-35 120.4 0.0 1.1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX91137.1 - 1.9e-14 53.9 1.1 2.7e-11 43.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91137.1 - 6.6e-06 25.6 0.1 0.00034 20.0 0.0 2.4 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX91137.1 - 1.9e-05 24.0 0.3 0.00049 19.4 0.1 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KFX91137.1 - 0.00077 18.6 0.3 1.6 7.7 0.0 3.2 4 0 0 4 4 4 2 Lycopene cyclase protein DUF3425 PF11905.8 KFX91138.1 - 2.9e-18 66.0 0.1 5.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ParD_like PF11903.8 KFX91138.1 - 0.051 13.6 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system DUF2273 PF10031.9 KFX91139.1 - 0.098 12.7 0.1 0.098 12.7 0.1 2.8 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) DUF2781 PF10914.8 KFX91140.1 - 1.1e-33 116.8 10.4 1.2e-33 116.6 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) LapA_dom PF06305.11 KFX91141.1 - 0.61 9.9 7.7 0.29 11.0 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LMWPc PF01451.21 KFX91146.1 - 1e-39 136.1 0.0 1.2e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Catalase PF00199.19 KFX91149.1 - 5.3e-158 526.1 2.8 6e-158 525.9 2.8 1.0 1 0 0 1 1 1 1 Catalase ECH_1 PF00378.20 KFX91150.1 - 2.9e-64 216.8 0.1 4.1e-64 216.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX91150.1 - 4.3e-32 111.9 1.0 1.7e-31 110.0 0.1 2.1 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase Paf1 PF03985.13 KFX91151.1 - 1.8e-78 264.5 0.0 2.1e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 KFX91151.1 - 1.2e-76 256.3 2.3 1.7e-76 255.7 2.3 1.2 1 0 0 1 1 1 1 Rer1 family Arf PF00025.21 KFX91152.1 - 1.6e-73 245.9 0.0 1.8e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFX91152.1 - 2.9e-14 53.3 0.0 3.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX91152.1 - 8.2e-13 48.2 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFX91152.1 - 1.4e-10 40.9 0.4 1.8e-06 27.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFX91152.1 - 2.4e-10 40.2 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFX91152.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX91152.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX91152.1 - 0.00086 18.9 0.0 0.07 12.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFX91152.1 - 0.0094 15.5 0.5 0.034 13.7 0.5 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KFX91152.1 - 0.13 12.9 0.1 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Actin PF00022.19 KFX91153.1 - 7.7e-22 77.5 0.0 2.4e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KFX91153.1 - 5.3e-11 42.3 0.1 1e-05 24.9 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KFX91153.1 - 0.035 12.9 0.1 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 KFX91153.1 - 0.07 13.6 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA DUF2114 PF09887.9 KFX91153.1 - 0.093 11.2 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) GluRS_N PF18466.1 KFX91155.1 - 0.079 13.4 0.4 0.24 11.8 0.4 1.9 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain Cyto_heme_lyase PF01265.17 KFX91156.1 - 2.6e-79 266.9 0.3 2.9e-79 266.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DHHW PF14286.6 KFX91166.1 - 0.54 9.5 1.8 1.1 8.5 1.8 1.5 1 0 0 1 1 1 0 DHHW protein Ten1 PF12658.7 KFX91167.1 - 1.3e-22 80.0 0.0 1.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Telomere capping, CST complex subunit CCDC24 PF15669.5 KFX91167.1 - 0.0031 17.4 1.8 0.06 13.2 0.0 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family Ten1_2 PF15490.6 KFX91167.1 - 0.0064 16.2 0.0 0.036 13.8 0.0 2.1 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit MotB_plug PF13677.6 KFX91167.1 - 0.095 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Snf7 PF03357.21 KFX91168.1 - 3.3e-32 111.4 20.8 3.3e-32 111.4 20.8 2.0 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.11 KFX91168.1 - 0.23 11.0 6.4 0.24 10.9 4.8 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.8 KFX91168.1 - 0.27 9.8 7.1 0.16 10.6 4.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.9 KFX91168.1 - 2 8.8 11.7 0.69 10.3 5.4 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltransf_25 PF13649.6 KFX91169.1 - 5.1e-12 46.3 0.1 1.5e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX91169.1 - 1.5e-11 44.8 0.1 4.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX91169.1 - 2.1e-10 40.7 0.7 3.4e-10 40.0 0.7 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91169.1 - 1.3e-09 38.7 0.0 2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91169.1 - 1.1e-08 35.0 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX91169.1 - 6.5e-07 28.9 0.1 4.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KFX91169.1 - 0.029 14.0 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KFX91169.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FYVE PF01363.21 KFX91189.1 - 6.6e-21 74.2 29.9 4.2e-16 58.8 8.3 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KFX91189.1 - 2.6e-19 68.7 1.5 5.6e-19 67.6 1.5 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KFX91189.1 - 8.6e-05 22.6 2.5 8.6e-05 22.6 2.5 4.3 5 1 1 6 6 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFX91189.1 - 0.00022 21.4 5.5 0.027 14.7 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding YqaH PF17448.2 KFX91189.1 - 0.063 13.6 1.0 0.21 11.9 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized YqaH-like ABC_tran_CTD PF16326.5 KFX91189.1 - 0.21 11.8 5.8 9.7 6.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Flagellin_N PF00669.20 KFX91189.1 - 0.25 11.5 1.9 23 5.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region zf-C2H2_2 PF12756.7 KFX91189.1 - 0.38 11.1 12.1 0.78 10.1 0.0 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFX91189.1 - 0.68 10.9 0.0 0.68 10.9 0.0 6.4 5 1 1 6 6 6 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KFX91189.1 - 0.84 9.6 3.1 6.1 6.9 0.4 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-WRNIP1_ubi PF18279.1 KFX91189.1 - 0.87 10.4 3.5 32 5.5 0.1 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Ion_trans PF00520.31 KFX91191.1 - 3.9e-09 36.1 21.9 8.6e-09 35.0 21.9 1.5 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KFX91191.1 - 2.1e-05 23.4 17.5 0.00022 20.0 17.5 2.1 1 1 0 1 1 1 1 Polycystin cation channel DHHC PF01529.20 KFX91191.1 - 1.2 9.3 7.8 3.4 7.8 1.5 2.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Whi5 PF08528.11 KFX91192.1 - 1.5e-08 34.1 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Asp PF00026.23 KFX91194.1 - 8.3e-64 216.0 6.3 9.9e-64 215.7 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX91194.1 - 2.2e-07 31.3 0.7 0.021 15.0 0.4 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX91194.1 - 0.00035 21.1 4.2 0.048 14.3 2.1 3.4 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX91194.1 - 0.2 12.2 4.9 1.3 9.7 0.4 3.4 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease APH PF01636.23 KFX91195.1 - 2.5e-13 50.5 0.0 6e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX91195.1 - 0.11 12.1 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 RIO1 family WSC PF01822.19 KFX91196.1 - 2e-36 124.1 30.0 6.9e-19 67.8 9.4 2.7 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 KFX91196.1 - 3.2e-19 69.5 0.1 6.4e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Peroxidase Sporozoite_P67 PF05642.11 KFX91196.1 - 0.16 10.1 7.5 0.21 9.7 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SET PF00856.28 KFX91197.1 - 5.5e-16 59.4 0.0 1.8e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 SET domain TENA_THI-4 PF03070.16 KFX91207.1 - 5e-13 49.3 0.0 5.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.12 KFX91208.1 - 5.2e-82 274.9 2.0 7.8e-82 274.3 2.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KFX91208.1 - 1.4e-28 100.2 0.3 2.4e-28 99.4 0.3 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KFX91208.1 - 2e-05 24.1 0.1 8.6e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 KFX91208.1 - 0.0012 18.4 1.2 0.002 17.6 1.2 1.4 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KFX91208.1 - 0.054 12.9 2.7 0.41 10.0 0.0 2.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family adh_short PF00106.25 KFX91209.1 - 1.9e-17 63.3 0.3 3e-17 62.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91209.1 - 2.8e-15 56.5 0.4 4.5e-15 55.8 0.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91209.1 - 0.00019 21.4 0.1 0.0004 20.3 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX91209.1 - 0.0097 15.8 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding CHASE8 PF17152.4 KFX91209.1 - 0.096 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain LRR_8 PF13855.6 KFX91209.1 - 1.3 8.8 7.2 12 5.7 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat Rad9 PF04139.13 KFX91210.1 - 1.7e-49 168.6 0.2 2e-49 168.3 0.2 1.1 1 0 0 1 1 1 1 Rad9 KH_1 PF00013.29 KFX91212.1 - 9.3e-39 131.1 13.2 3.3e-16 58.9 0.1 3.7 4 0 0 4 4 4 3 KH domain RabGAP-TBC PF00566.18 KFX91212.1 - 4.8e-32 111.4 1.5 1.2e-31 110.1 1.5 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain KH_2 PF07650.17 KFX91212.1 - 2.5e-08 33.6 9.2 0.027 14.3 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFX91212.1 - 3.1e-06 26.9 5.3 0.1 12.5 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFX91212.1 - 0.0034 17.4 5.5 0.58 10.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain RRM_1 PF00076.22 KFX91219.1 - 7.9e-10 38.4 0.0 3.1e-07 30.1 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MWFE PF15879.5 KFX91219.1 - 0.1 12.8 0.0 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit CAF-1_p150 PF11600.8 KFX91219.1 - 9.9 5.8 22.9 0.74 9.5 17.4 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NMD3 PF04981.13 KFX91220.1 - 4.2e-79 265.4 1.6 7.2e-79 264.7 1.6 1.4 1 0 0 1 1 1 1 NMD3 family Phenol_Hydrox PF02332.18 KFX91220.1 - 0.0024 17.5 0.1 0.005 16.4 0.1 1.5 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase DUF35_N PF12172.8 KFX91220.1 - 0.017 15.0 1.1 4 7.4 0.2 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HTH_49 PF18010.1 KFX91220.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain DZR PF12773.7 KFX91220.1 - 9.3 6.4 11.0 1.2e+03 -0.3 11.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon UPF0086 PF01868.16 KFX91221.1 - 1.6e-31 108.0 0.2 2.2e-31 107.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 KFX91222.1 - 1.8e-15 56.7 0.0 4.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TPR_14 PF13428.6 KFX91223.1 - 0.0024 18.5 0.9 0.011 16.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX91223.1 - 0.011 15.4 1.8 0.023 14.4 1.8 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 KFX91223.1 - 0.018 15.4 0.7 0.38 11.1 0.6 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX91223.1 - 0.019 15.0 2.8 0.11 12.6 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX91223.1 - 0.026 15.0 0.1 0.071 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX91223.1 - 0.23 11.3 5.9 0.39 10.6 0.6 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 KFX91223.1 - 4 7.2 11.5 2.2 8.1 9.5 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein HAD_2 PF13419.6 KFX91224.1 - 5e-16 59.3 0.0 1.1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX91224.1 - 1.3e-08 35.4 0.0 1.1e-06 29.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX91224.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.12 KFX91224.1 - 0.033 14.1 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) SET PF00856.28 KFX91231.1 - 5.4e-11 43.2 0.4 5.1e-10 40.0 0.4 2.2 1 1 0 1 1 1 1 SET domain Helicase_C PF00271.31 KFX91232.1 - 3.4e-07 30.6 0.0 7.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX91232.1 - 6.9e-06 25.9 0.2 2.1e-05 24.4 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DNA_pol_A_exo1 PF01612.20 KFX91232.1 - 0.071 12.8 0.0 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease Dimer_Tnp_hAT PF05699.14 KFX91233.1 - 1.2e-17 63.4 0.0 2.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFX91233.1 - 0.0013 19.1 1.1 0.0017 18.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) IL11 PF07400.11 KFX91233.1 - 0.098 12.3 0.2 0.22 11.2 0.2 1.6 1 0 0 1 1 1 0 Interleukin 11 Ank_4 PF13637.6 KFX91235.1 - 8.3e-18 64.5 1.9 8.6e-07 29.4 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX91235.1 - 1.3e-17 64.2 0.2 2.4e-08 34.5 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX91235.1 - 4.7e-17 60.3 3.4 0.00018 21.7 0.1 6.4 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFX91235.1 - 9.3e-15 54.5 3.7 1.6e-06 28.3 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX91235.1 - 1.2e-14 54.0 4.5 1.2e-05 25.6 0.9 4.6 4 0 0 4 4 4 2 Ankyrin repeat F-box-like PF12937.7 KFX91235.1 - 3.7e-05 23.5 0.0 8.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like CBFB_NFYA PF02045.15 KFX91239.1 - 8.4e-28 96.8 4.6 8.4e-28 96.8 4.6 2.5 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ORC6 PF05460.13 KFX91239.1 - 0.099 11.9 4.2 0.2 10.9 4.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hus1 PF04005.12 KFX91239.1 - 0.26 10.3 0.0 0.45 9.6 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Ras PF00071.22 KFX91240.1 - 2.7e-40 137.6 0.0 3e-38 131.0 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFX91240.1 - 4e-31 107.7 0.0 5.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX91240.1 - 1.9e-10 40.4 0.0 3.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX91240.1 - 0.00047 19.6 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX91240.1 - 0.0041 17.2 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX91240.1 - 0.0083 16.5 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFX91240.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFX91240.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX91240.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFX91240.1 - 0.076 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 KFX91240.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Lys PF00062.20 KFX91241.1 - 0.00017 21.8 0.1 0.00023 21.4 0.1 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family F-box-like PF12937.7 KFX91242.1 - 2.4e-05 24.1 0.1 0.00013 21.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like DAGK_cat PF00781.24 KFX91243.1 - 2.5e-07 30.4 0.2 3.6e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_S41 PF03572.18 KFX91245.1 - 6.5e-07 29.1 0.0 1.9e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 CDC73_C PF05179.14 KFX91257.1 - 9.6e-25 87.1 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Phage_NinH PF06322.11 KFX91259.1 - 0.23 11.3 0.6 0.53 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage NinH protein NAD_binding_5 PF07994.12 KFX91270.1 - 2.9e-144 480.4 0.1 3.5e-144 480.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFX91270.1 - 6e-46 155.2 0.3 1.3e-45 154.1 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase polyprenyl_synt PF00348.17 KFX91271.1 - 5.6e-46 156.7 0.0 1.1e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KFX91271.1 - 9.5e-07 28.4 0.0 0.00029 20.3 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain zinc_ribbon_5 PF13719.6 KFX91272.1 - 0.19 11.5 0.6 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PI-PLC-X PF00388.19 KFX91274.1 - 2.4e-58 195.9 0.1 3.9e-58 195.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFX91274.1 - 1.5e-42 144.5 0.0 3.5e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFX91274.1 - 1.1e-06 28.9 0.0 1.8e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 KFX91274.1 - 0.047 14.2 0.1 0.095 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Oxidored_molyb PF00174.19 KFX91276.1 - 1.3e-42 145.3 0.1 2.6e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFX91276.1 - 6.2e-28 97.5 0.7 1.1e-27 96.8 0.7 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DUF2381 PF09544.10 KFX91276.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DoxA PF07680.11 KFX91276.1 - 0.19 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 TQO small subunit DoxA Cytochrom_C_asm PF01578.20 KFX91285.1 - 0.017 14.9 0.5 0.026 14.3 0.1 1.5 2 0 0 2 2 2 0 Cytochrome C assembly protein MARVEL PF01284.23 KFX91285.1 - 0.11 12.5 2.6 0.52 10.3 2.6 1.8 1 1 0 1 1 1 0 Membrane-associating domain zf-C2H2_jaz PF12171.8 KFX91291.1 - 1.1e-05 25.5 0.7 0.12 12.7 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFX91291.1 - 0.00011 22.4 20.4 0.0092 16.4 1.0 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-DNA_Pol PF08996.10 KFX91291.1 - 0.0053 16.5 2.6 0.0098 15.7 2.6 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-C2H2_6 PF13912.6 KFX91291.1 - 0.0097 15.9 0.6 0.0097 15.9 0.6 3.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFX91291.1 - 0.015 15.6 0.2 0.32 11.4 0.0 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFX91291.1 - 0.044 14.2 3.0 0.59 10.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFX91291.1 - 0.073 13.2 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger FliC_SP PF12613.8 KFX91291.1 - 0.096 13.2 2.6 0.21 12.1 2.6 1.4 1 0 0 1 1 1 0 Flagellin structural protein zf-C6H2 PF15801.5 KFX91291.1 - 0.15 12.4 3.8 3.3 8.1 0.1 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2_4 PF13894.6 KFX91291.1 - 1.7 9.7 19.3 0.29 12.1 0.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFX91291.1 - 1.9 9.2 6.2 7.7 7.2 0.1 3.7 1 1 2 3 3 3 0 FOXP coiled-coil domain DJ-1_PfpI PF01965.24 KFX91292.1 - 1.7e-13 50.7 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.6 KFX91294.1 - 0.0015 18.8 0.9 18 5.7 0.2 4.4 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX91294.1 - 0.18 12.0 6.0 12 6.3 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KFX91295.1 - 0.0027 17.8 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KFX91296.1 - 1.6e-40 139.8 0.0 1.8e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFX91296.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX91296.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX91296.1 - 0.069 13.1 0.2 6 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF92 PF01940.16 KFX91297.1 - 1.2e-85 286.8 2.6 1.8e-85 286.1 2.6 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF92 FAD_binding_3 PF01494.19 KFX91297.1 - 5.7e-76 256.0 0.0 7.9e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX91297.1 - 1.1e-05 25.2 0.0 0.11 12.1 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91297.1 - 3.6e-05 23.1 0.1 0.16 11.2 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91297.1 - 0.00011 21.5 0.1 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX91297.1 - 0.053 12.6 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KFX91297.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KFX91297.1 - 0.11 11.5 0.0 0.58 9.2 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase DUF4342 PF14242.6 KFX91297.1 - 0.39 10.7 2.7 12 6.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) SAGA-Tad1 PF12767.7 KFX91298.1 - 6.1e-58 196.3 0.0 7.5e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 KFX91299.1 - 3.3e-101 338.8 0.0 5.8e-101 338.0 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFX91299.1 - 1.3e-83 281.1 0.0 3.5e-83 279.7 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF3921 PF13060.6 KFX91299.1 - 0.071 13.1 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) WD40 PF00400.32 KFX91300.1 - 3.6e-32 109.9 28.6 1.2e-05 26.0 0.3 10.8 10 1 1 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91300.1 - 1.2e-18 67.1 5.2 6.3e-07 29.6 0.0 6.3 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX91300.1 - 0.00017 21.5 2.2 3.3 7.5 0.0 4.6 4 3 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFX91300.1 - 0.0021 17.4 3.8 2.6 7.3 0.0 4.7 4 2 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KFX91300.1 - 0.0046 16.9 2.9 3 7.9 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX91300.1 - 0.01 14.9 3.4 5.1 6.0 0.2 4.2 3 2 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KFX91300.1 - 0.038 12.9 0.0 0.44 9.3 0.0 2.6 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) GspH PF12019.8 KFX91300.1 - 0.039 14.4 8.1 0.73 10.3 0.1 4.0 4 1 1 5 5 5 0 Type II transport protein GspH DBP10CT PF08147.12 KFX91300.1 - 0.1 12.9 1.1 0.8 10.0 0.8 2.4 2 0 0 2 2 2 0 DBP10CT (NUC160) domain BLM10_mid PF16507.5 KFX91305.1 - 3.5e-199 662.8 0.0 5.7e-199 662.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 KFX91305.1 - 1.9e-20 73.0 0.0 4.8e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT_EZ PF13513.6 KFX91305.1 - 0.3 11.6 1.0 6.7 7.3 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat p450 PF00067.22 KFX91306.1 - 4.3e-62 210.4 0.0 5.5e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFX91307.1 - 8e-68 229.3 0.0 7.9e-67 226.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 KFX91308.1 - 2e-29 102.8 2.9 3.1e-29 102.2 2.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX91308.1 - 1.1e-21 77.5 0.3 2e-21 76.6 0.3 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain FAD_binding_3 PF01494.19 KFX91308.1 - 5.8e-13 48.8 0.1 1.6e-12 47.3 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain CBM_1 PF00734.18 KFX91308.1 - 2.7e-05 24.0 9.1 7.3e-05 22.6 9.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Pyr_redox_3 PF13738.6 KFX91308.1 - 6e-05 22.4 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX91308.1 - 0.0001 21.5 0.0 0.00021 20.5 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX91308.1 - 0.00014 21.2 0.2 0.46 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX91308.1 - 0.00022 20.6 0.4 0.043 13.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX91308.1 - 0.00085 19.5 0.1 0.0037 17.5 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HTH_Tnp_Tc3_2 PF01498.18 KFX91308.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Transposase Pyr_redox PF00070.27 KFX91308.1 - 0.35 11.5 4.0 0.73 10.4 0.2 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX91308.1 - 0.89 9.1 3.5 0.81 9.2 0.8 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Isochorismatase PF00857.20 KFX91309.1 - 2.1e-14 54.1 0.1 5.2e-14 52.8 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family Pyr_redox_2 PF07992.14 KFX91310.1 - 2e-29 102.8 0.0 2.6e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX91310.1 - 6.9e-12 45.8 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91310.1 - 3.6e-07 29.7 0.0 4.9e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX91310.1 - 6.1e-06 25.6 0.0 8.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 KFX91310.1 - 0.0037 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KFX91310.1 - 0.063 12.1 0.1 6.3 5.5 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Fungal_trans_2 PF11951.8 KFX91311.1 - 1.1e-34 119.8 4.1 1.5e-34 119.5 4.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91311.1 - 1.4e-05 25.1 7.8 2.6e-05 24.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.16 KFX91312.1 - 0.004 17.2 0.1 0.006 16.7 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Epimerase PF01370.21 KFX91313.1 - 3.4e-14 52.9 0.1 5.2e-13 49.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX91313.1 - 2.9e-05 24.0 0.1 7.2e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFX91313.1 - 5.3e-05 23.5 0.0 8.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFX91313.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFX91313.1 - 0.031 13.4 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX91313.1 - 0.067 12.6 0.1 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX91313.1 - 0.12 11.5 0.3 2.1 7.4 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein TPR_2 PF07719.17 KFX91314.1 - 3.8e-09 36.0 13.0 0.014 15.5 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFX91314.1 - 8.5e-06 25.4 7.3 0.34 10.8 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX91314.1 - 0.0012 19.5 18.5 0.73 10.8 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX91314.1 - 0.0025 17.5 9.0 3.4 7.4 0.1 5.8 6 0 0 6 6 6 1 TPR repeat TPR_4 PF07721.14 KFX91314.1 - 0.0046 17.4 6.0 0.36 11.6 2.2 4.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX91314.1 - 0.0053 17.2 8.3 1.4 9.5 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX91314.1 - 0.013 15.8 8.2 0.55 10.6 3.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX91314.1 - 0.039 14.4 3.1 2.1e+02 2.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX91314.1 - 0.059 13.4 1.4 2.9 8.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX91314.1 - 1.5 9.3 8.2 6.8 7.2 0.5 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX91314.1 - 6.8 7.4 24.4 1.6 9.4 0.2 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat O-FucT PF10250.9 KFX91318.1 - 1.7e-05 24.7 0.0 1.9e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TAL_FSA PF00923.19 KFX91319.1 - 5.6e-95 318.0 0.5 6.3e-95 317.8 0.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase FAS_I_H PF18314.1 KFX91334.1 - 5.1e-78 261.4 0.0 1.2e-77 260.2 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KFX91334.1 - 1.9e-74 249.4 0.0 3.7e-74 248.5 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KFX91334.1 - 1.1e-18 67.8 0.0 2.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KFX91334.1 - 5e-16 58.9 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KFX91334.1 - 6e-11 42.4 0.3 2.2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain GATase PF00117.28 KFX91335.1 - 3.6e-31 108.4 0.0 4.2e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFX91335.1 - 6.2e-07 29.4 0.3 2.9e-05 23.9 0.3 2.1 1 1 0 1 1 1 1 Peptidase C26 Sporozoite_P67 PF05642.11 KFX91337.1 - 0.65 8.0 8.3 0.69 7.9 8.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box PF00646.33 KFX91350.1 - 2.1e-07 30.6 0.1 4.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX91350.1 - 2.6e-05 24.0 0.2 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like Peptidase_M20 PF01546.28 KFX91354.1 - 1.4e-18 67.3 0.0 2.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KFX91354.1 - 9.2e-12 45.3 3.0 0.028 15.3 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 KFX91354.1 - 8.6e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KFX91354.1 - 0.0053 17.0 0.1 7.8 6.9 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M28 PF04389.17 KFX91354.1 - 0.011 15.4 0.1 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 Tim17 PF02466.19 KFX91355.1 - 1.7e-32 112.1 8.5 2.1e-32 111.8 8.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 KFX91355.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal DUF116 PF01976.17 KFX91355.1 - 0.25 10.8 0.1 0.31 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF116 Asparaginase_2 PF01112.18 KFX91356.1 - 0.012 14.6 0.4 0.02 13.9 0.4 1.6 1 1 0 1 1 1 0 Asparaginase Ribonuc_L-PSP PF01042.21 KFX91358.1 - 9.6e-39 132.1 0.0 1.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DDE_Tnp_4 PF13359.6 KFX91358.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Ribosomal_L14 PF00238.19 KFX91359.1 - 4.3e-33 114.0 0.0 5.1e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.19 KFX91360.1 - 1e-81 274.8 0.1 1.8e-81 274.0 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 KFX91361.1 - 3.4e-33 114.1 0.0 7.1e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFX91361.1 - 3.3e-11 43.6 0.5 6e-11 42.7 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFX91361.1 - 1.5e-07 31.2 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PTR2 PF00854.21 KFX91362.1 - 4.2e-76 256.3 9.0 5.5e-76 255.9 9.0 1.1 1 0 0 1 1 1 1 POT family Rod_cone_degen PF15201.6 KFX91362.1 - 0.0072 16.4 0.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 1 Progressive rod-cone degeneration DUF2304 PF10066.9 KFX91362.1 - 5 7.4 8.5 13 6.1 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Aldedh PF00171.22 KFX91363.1 - 4.6e-135 450.7 1.3 5.5e-135 450.4 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_18 PF00704.28 KFX91366.1 - 2.5e-18 66.9 0.6 7.3e-18 65.3 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Vps62 PF06101.11 KFX91367.1 - 0.00018 20.0 0.0 0.00029 19.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Kp4 PF09044.10 KFX91370.1 - 1.3e-37 128.7 1.6 1.5e-37 128.4 1.6 1.1 1 0 0 1 1 1 1 Kp4 GST_N_2 PF13409.6 KFX91371.1 - 1e-06 28.9 0.1 2.1e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX91371.1 - 4.3e-05 23.8 0.1 9.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sld7_C PF18596.1 KFX91371.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Sld7 C-terminal domain TcA_TcB_BD PF18276.1 KFX91371.1 - 0.17 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Zn_clus PF00172.18 KFX91371.1 - 0.61 10.3 5.2 0.11 12.6 0.7 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFX91376.1 - 1.2e-90 304.6 17.3 1.5e-90 304.3 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91376.1 - 2e-23 82.9 17.8 2e-23 82.9 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX91376.1 - 0.061 12.2 17.2 0.049 12.5 4.3 2.2 2 0 0 2 2 2 0 MFS_1 like family SHR3_chaperone PF08229.11 KFX91378.1 - 5.1e-78 260.4 0.0 5.7e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5362 PF17319.2 KFX91378.1 - 0.035 13.9 1.1 0.086 12.7 1.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5362) DUF202 PF02656.15 KFX91378.1 - 0.13 12.8 3.0 7.6 7.1 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF5453 PF17534.2 KFX91378.1 - 0.39 10.7 3.0 1.3 9.0 3.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5453) IBN_N PF03810.19 KFX91382.1 - 4e-12 45.9 0.1 5.8e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFX91382.1 - 5.8e-05 22.1 0.1 0.00013 20.9 0.1 1.6 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 KFX91382.1 - 0.029 14.5 0.2 0.54 10.5 0.1 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 GRIP PF01465.20 KFX91382.1 - 0.037 13.9 0.1 0.31 11.0 0.1 2.7 1 1 0 1 1 1 0 GRIP domain Vac14_Fab1_bd PF12755.7 KFX91382.1 - 0.093 13.3 1.6 3.9 8.1 0.1 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 KFX91382.1 - 0.24 11.5 4.8 11 6.0 0.0 4.8 7 0 0 7 7 7 0 Exportin 1-like protein HEAT_EZ PF13513.6 KFX91382.1 - 1.1 9.8 4.0 29 5.3 0.7 4.6 4 1 0 4 4 4 0 HEAT-like repeat BUD22 PF09073.10 KFX91382.1 - 1.6 8.0 5.5 2.5 7.4 5.5 1.2 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 KFX91385.1 - 9.5e-41 139.9 96.5 3.5e-37 128.1 60.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX91386.1 - 3.7e-14 52.8 0.0 2.8e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX91386.1 - 1.8e-11 43.6 0.0 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX91386.1 - 9.9e-11 41.6 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX91386.1 - 2.4e-09 37.4 0.1 3.6e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFX91386.1 - 1.5e-08 34.1 0.1 2.9e-07 29.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFX91386.1 - 2.3e-05 23.7 0.1 3.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFX91386.1 - 0.00047 19.8 0.2 0.00073 19.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFX91386.1 - 0.00074 19.0 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX91386.1 - 0.0044 17.0 0.8 0.02 14.8 0.8 2.3 1 1 0 1 1 1 1 KR domain FMN_dh PF01070.18 KFX91387.1 - 2.8e-105 352.2 0.0 3.3e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFX91387.1 - 3.1e-20 72.1 0.0 6.3e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KFX91387.1 - 1.5e-05 24.2 0.0 0.00053 19.1 0.0 2.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFX91387.1 - 9.2e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribul_P_3_epim PF00834.19 KFX91387.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.15 KFX91387.1 - 0.18 11.1 0.3 0.3 10.4 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase 2-Hacid_dh_C PF02826.19 KFX91388.1 - 9e-55 184.8 0.0 1.2e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX91388.1 - 2.1e-21 76.0 0.0 2.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX91388.1 - 0.0026 17.9 0.1 0.0059 16.8 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX91388.1 - 0.029 15.0 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 KFX91388.1 - 0.089 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans PF04082.18 KFX91389.1 - 1.1e-09 37.7 0.0 1.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91389.1 - 4.9e-07 29.8 7.4 8.9e-07 28.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX91390.1 - 2.1e-50 170.9 0.0 4.9e-50 169.7 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91390.1 - 1.8e-47 161.9 0.1 2.3e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91390.1 - 5.7e-11 42.7 0.2 8.7e-11 42.0 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91390.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 KFX91391.1 - 3.6e-27 94.4 0.6 6.5e-27 93.6 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX91391.1 - 6.1e-19 68.3 0.2 1.1e-18 67.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX91391.1 - 1.2e-12 47.7 0.2 1e-10 41.4 0.2 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFX91391.1 - 0.0022 19.1 0.0 0.0056 17.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX91391.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KFX91391.1 - 0.034 13.4 0.3 0.071 12.4 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TT_ORF2 PF02957.15 KFX91392.1 - 0.089 13.7 0.7 0.089 13.7 0.7 1.4 1 1 0 1 1 1 0 TT viral ORF2 TPR_7 PF13176.6 KFX91393.1 - 0.056 13.5 0.0 0.51 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Dynamin_N PF00350.23 KFX91396.1 - 3.5e-12 46.7 0.3 1.7e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFX91396.1 - 2.2e-06 27.8 0.0 6.1e-05 23.1 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX91396.1 - 9.6e-05 22.3 0.0 0.00037 20.4 0.0 2.0 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KFX91396.1 - 0.00033 21.2 0.2 0.0041 17.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.13 KFX91396.1 - 0.00037 19.7 0.0 0.0013 17.9 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 KFX91396.1 - 0.017 15.6 2.4 0.067 13.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain CD34_antigen PF06365.12 KFX91396.1 - 0.081 12.5 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Septin PF00735.18 KFX91396.1 - 0.12 11.7 0.2 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 Septin PHC2_SAM_assoc PF16616.5 KFX91396.1 - 1.7 9.5 6.3 0.89 10.4 2.3 2.6 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 ABC2_membrane_2 PF12679.7 KFX91397.1 - 1.1 8.4 7.4 1.6 8.0 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RRM_1 PF00076.22 KFX91398.1 - 1.9e-07 30.8 0.0 4.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTP_transf_3 PF12804.7 KFX91398.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF5320 PF17253.2 KFX91398.1 - 0.02 15.9 0.1 3.7 8.7 0.1 3.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF2408 PF10303.9 KFX91398.1 - 0.032 14.8 2.6 0.062 13.9 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-H2C2_2 PF13465.6 KFX91398.1 - 0.039 14.4 0.6 0.039 14.4 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain CorA PF01544.18 KFX91398.1 - 0.15 11.3 0.5 0.25 10.6 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ARA70 PF12489.8 KFX91398.1 - 0.23 11.6 6.7 0.33 11.1 4.8 2.1 1 1 1 2 2 2 0 Nuclear coactivator HsbA PF12296.8 KFX91398.1 - 0.23 11.9 1.1 9 6.8 0.2 2.6 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Phage_GPO PF05929.11 KFX91398.1 - 0.57 9.8 4.1 0.28 10.8 1.4 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase LMBR1 PF04791.16 KFX91398.1 - 2.7 6.8 5.0 0.36 9.7 1.0 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Ribosomal_S13 PF00416.22 KFX91404.1 - 1.7e-55 186.8 2.7 2e-55 186.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KFX91404.1 - 0.0074 15.1 0.0 0.019 13.8 0.0 1.4 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KFX91404.1 - 0.039 14.2 0.1 0.2 11.9 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KFX91404.1 - 0.04 14.3 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SBDS_C PF09377.10 KFX91405.1 - 1.5e-42 144.2 0.2 2.9e-42 143.4 0.1 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 KFX91405.1 - 3.2e-35 120.1 1.4 6.7e-35 119.0 1.4 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 KFX91405.1 - 0.1 12.6 0.2 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Peptidase_S10 PF00450.22 KFX91406.1 - 8e-128 427.4 0.7 9.7e-128 427.1 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KFX91406.1 - 1.7e-18 67.4 0.7 6.7e-18 65.4 0.7 2.0 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_L13e PF01294.18 KFX91407.1 - 3.9e-75 251.6 5.8 5.8e-75 251.1 5.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Hormone_2 PF00123.20 KFX91407.1 - 0.17 11.8 2.0 0.38 10.7 2.0 1.6 1 0 0 1 1 1 0 Peptide hormone Amidoligase_2 PF12224.8 KFX91408.1 - 4.8e-20 72.3 0.0 6.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Abhydrolase_1 PF00561.20 KFX91409.1 - 5e-24 85.3 0.0 3.4e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KFX91409.1 - 4.6e-21 74.9 0.0 8.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FA_hydroxylase PF04116.13 KFX91410.1 - 1.6e-20 73.8 12.7 1.6e-20 73.8 12.7 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Hexapep PF00132.24 KFX91411.1 - 5.5e-16 57.6 16.9 1.1e-11 44.0 4.2 4.1 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX91411.1 - 4.1e-14 52.0 8.8 6.4e-08 32.2 4.5 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KFX91411.1 - 1.4e-07 31.6 0.1 2.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase NolB PF17398.2 KFX91411.1 - 0.078 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolB Glyco_hydro_1 PF00232.18 KFX91412.1 - 3.1e-100 335.8 0.0 3.7e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4038 PF13204.6 KFX91412.1 - 0.024 14.3 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) TruD PF01142.18 KFX91413.1 - 4.3e-63 213.6 0.1 4.4e-57 193.8 0.0 4.3 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.17 KFX91413.1 - 0.0015 18.3 0.0 0.0045 16.7 0.0 1.9 1 1 0 1 1 1 1 SAD/SRA domain PLA2_B PF01735.18 KFX91418.1 - 2.6e-196 652.8 1.6 3e-196 652.6 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Cupin_2 PF07883.11 KFX91419.1 - 0.00011 21.8 0.1 0.002 17.8 0.1 2.3 1 1 0 1 1 1 1 Cupin domain SWIRM-assoc_2 PF16496.5 KFX91420.1 - 0.0018 17.2 0.1 0.0018 17.2 0.1 2.9 3 1 1 4 4 4 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 KFX91420.1 - 1.1 9.3 14.5 1.5 9.0 0.3 4.3 3 0 0 3 3 3 0 AT hook motif adh_short PF00106.25 KFX91421.1 - 7.1e-27 94.1 0.5 7.5e-26 90.8 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91421.1 - 3.6e-18 66.0 0.1 2.9e-17 63.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91421.1 - 3.8e-08 33.5 0.3 1.2e-07 31.9 0.4 1.7 2 0 0 2 2 2 1 KR domain DUF3073 PF11273.8 KFX91421.1 - 0.15 12.8 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF3425 PF11905.8 KFX91422.1 - 2.3e-17 63.1 0.3 4.8e-17 62.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.18 KFX91423.1 - 4e-24 85.1 1.8 4.5e-24 84.9 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91423.1 - 4.6e-08 33.1 4.3 9.9e-08 32.0 4.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX91424.1 - 2.6e-38 131.9 28.3 2.6e-38 131.9 28.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX91424.1 - 9e-06 24.4 1.8 1.4e-05 23.8 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX91424.1 - 0.039 12.3 6.5 0.028 12.7 3.8 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family bZIP_1 PF00170.21 KFX91425.1 - 7.3e-05 22.8 6.0 0.00011 22.2 6.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX91425.1 - 0.0079 16.3 6.1 0.012 15.6 6.1 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFX91425.1 - 0.15 12.6 8.9 0.31 11.6 8.8 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor DJ-1_PfpI PF01965.24 KFX91426.1 - 8.1e-07 29.0 0.0 2.1e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFX91426.1 - 7e-05 22.6 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like Sugar_tr PF00083.24 KFX91426.1 - 0.059 12.2 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter adh_short PF00106.25 KFX91427.1 - 3.3e-40 137.7 0.0 4.1e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91427.1 - 6.5e-19 68.4 0.0 8.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91427.1 - 7.5e-14 52.0 0.0 9.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFX91427.1 - 0.00013 22.5 0.1 0.00028 21.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFX91427.1 - 0.00013 22.0 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFX91427.1 - 0.00014 21.4 0.1 0.00045 19.7 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFX91427.1 - 0.00024 20.7 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFX91427.1 - 0.00061 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFX91427.1 - 0.00067 18.9 0.1 0.00076 18.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KFX91427.1 - 0.0092 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFX91427.1 - 0.038 13.9 0.2 0.077 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFX91427.1 - 0.054 13.1 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 KFX91427.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KFX91427.1 - 0.082 12.8 0.1 0.21 11.5 0.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 KFX91427.1 - 0.086 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain RimK PF08443.11 KFX91427.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain NAGLU_N PF12971.7 KFX91427.1 - 0.1 12.4 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Methyltransf_2 PF00891.18 KFX91428.1 - 5e-15 55.4 0.3 1.4e-14 53.9 0.1 1.8 2 1 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFX91428.1 - 0.0097 15.9 0.1 0.024 14.6 0.1 1.7 1 1 0 1 1 1 1 Dimerisation domain Ras PF00071.22 KFX91429.1 - 7.4e-05 22.4 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 2 Ras family WW PF00397.26 KFX91430.1 - 0.064 13.4 6.3 0.14 12.2 6.3 1.7 1 0 0 1 1 1 0 WW domain UbiA PF01040.18 KFX91431.1 - 7.3e-58 195.8 23.0 1.1e-57 195.2 23.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1180 PF06679.12 KFX91431.1 - 4.9 7.5 7.4 1.5 9.2 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Myb_DNA-bind_6 PF13921.6 KFX91432.1 - 8.6e-06 25.9 0.4 2e-05 24.7 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX91432.1 - 1.1e-05 25.5 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ferric_reduct PF01794.19 KFX91435.1 - 1.3e-14 54.4 5.1 2.6e-14 53.4 5.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX91435.1 - 0.0068 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Methylase_S PF01420.19 KFX91435.1 - 0.035 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain CTP_transf_like PF01467.26 KFX91440.1 - 7.4e-30 104.0 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 KFX91440.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) HIGH_NTase1 PF05636.11 KFX91440.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase NOC3p PF07540.11 KFX91441.1 - 3.6e-30 104.3 0.2 1.1e-29 102.7 0.2 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein Trypan_PARP PF05887.11 KFX91441.1 - 1.3 9.0 7.7 3.4 7.6 7.7 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) malic PF00390.19 KFX91444.1 - 8e-72 240.8 0.0 1.2e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 KFX91444.1 - 1.1e-50 172.4 0.0 1.6e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Peptidase_M18 PF02127.15 KFX91452.1 - 3.3e-157 523.7 0.0 6e-157 522.9 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Methyltransf_16 PF10294.9 KFX91453.1 - 2.4e-17 63.2 0.0 3.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFX91453.1 - 6.9e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX91453.1 - 1.1e-05 26.1 0.0 7.4e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX91453.1 - 0.0029 17.1 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFX91453.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 KFX91453.1 - 0.019 14.5 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KFX91453.1 - 0.025 15.2 0.0 0.1 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91453.1 - 0.097 12.5 0.0 0.73 9.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91453.1 - 0.13 13.0 0.0 0.69 10.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFX91453.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF4769 PF15992.5 KFX91456.1 - 1.4 8.6 4.5 1.6 8.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Glyco_transf_28 PF03033.20 KFX91457.1 - 2.3e-18 66.6 0.3 7.9e-11 42.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KFX91457.1 - 4.5e-06 26.9 0.0 1.7e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KFX91457.1 - 4.2e-05 22.5 0.0 6.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX91457.1 - 0.0024 17.9 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Sugar_tr PF00083.24 KFX91459.1 - 2.4e-78 264.0 20.2 2.8e-78 263.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91459.1 - 4.3e-33 114.7 52.5 2.7e-31 108.8 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX91459.1 - 5.5e-06 25.1 9.8 6.5e-06 24.8 0.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 KFX91459.1 - 0.0068 15.9 0.3 0.0068 15.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_1 PF07690.16 KFX91460.1 - 9e-34 116.9 71.7 4.2e-30 104.9 53.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX91461.1 - 2.5e-15 56.6 0.3 9.3e-15 54.7 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX91461.1 - 9.8e-11 41.2 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX91461.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX91461.1 - 4.3e-07 30.0 0.1 2e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KFX91461.1 - 1.8e-05 24.3 0.1 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KFX91461.1 - 2.3e-05 24.1 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KFX91461.1 - 0.00066 18.9 0.0 0.0026 17.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KFX91461.1 - 0.0016 18.4 0.4 0.011 15.7 0.4 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX91461.1 - 0.0059 15.8 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX91461.1 - 0.073 12.2 0.1 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.18 KFX91462.1 - 4.9e-10 38.9 0.0 8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91462.1 - 1.2e-06 28.5 12.8 2.2e-06 27.7 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 KFX91463.1 - 1.4e-49 168.8 0.0 1.6e-49 168.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KFX91464.1 - 3e-55 187.4 0.3 3.6e-55 187.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Epimerase PF01370.21 KFX91465.1 - 4.9e-12 45.8 0.1 1.6e-10 40.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX91465.1 - 1.2e-09 38.4 0.7 1.8e-09 37.8 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX91465.1 - 6.9e-08 32.3 0.7 1.2e-07 31.6 0.7 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFX91465.1 - 0.00012 22.5 0.1 0.00026 21.4 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFX91465.1 - 0.00074 18.6 0.1 0.18 10.7 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX91465.1 - 0.0064 15.7 0.0 0.023 13.8 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFX91465.1 - 0.02 14.0 0.1 0.064 12.4 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX91465.1 - 0.049 13.0 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KFX91465.1 - 0.079 13.2 0.3 0.28 11.4 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain CLCA PF08434.11 KFX91465.1 - 0.14 11.5 0.2 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel N terminal Fungal_trans_2 PF11951.8 KFX91466.1 - 2.8e-05 23.1 0.0 0.031 13.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain FBD PF08387.10 KFX91466.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 FBD Pkinase PF00069.25 KFX91467.1 - 2.9e-26 92.4 0.1 1.9e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91467.1 - 1.6e-07 30.9 0.1 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX91467.1 - 0.25 10.1 2.3 0.21 10.3 0.4 1.7 1 1 1 2 2 2 0 Fungal protein kinase SesA PF17107.5 KFX91475.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.0 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BAG PF02179.16 KFX91475.1 - 2 8.9 5.5 2.3 8.7 0.1 3.1 3 0 0 3 3 3 0 BAG domain Helo_like_N PF17111.5 KFX91477.1 - 0.00017 21.1 2.2 0.00017 21.1 2.2 2.1 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_7 PF13176.6 KFX91477.1 - 0.00031 20.5 0.8 0.16 12.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX91477.1 - 0.00039 20.2 0.2 0.11 12.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX91477.1 - 0.0027 17.7 0.5 1.8 8.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX91477.1 - 0.03 15.1 0.3 4.4 8.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX91477.1 - 0.3 11.4 5.2 12 6.3 0.2 3.5 3 1 2 5 5 5 0 Tetratricopeptide repeat Ifi-6-16 PF06140.13 KFX91478.1 - 0.00043 20.1 0.1 0.0014 18.5 0.1 1.9 1 0 0 1 1 1 1 Interferon-induced 6-16 family HCV_NS4a PF01006.20 KFX91478.1 - 0.013 15.2 0.2 0.039 13.7 0.2 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Utp14 PF04615.13 KFX91478.1 - 0.026 13.1 0.7 0.039 12.5 0.7 1.1 1 0 0 1 1 1 0 Utp14 protein Esterase_phd PF10503.9 KFX91479.1 - 3.3e-23 82.3 1.7 1.4e-22 80.3 1.7 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX91479.1 - 3.2e-13 49.7 1.3 4.4e-13 49.2 1.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX91479.1 - 0.0013 17.7 0.9 0.0055 15.6 0.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family adh_short_C2 PF13561.6 KFX91480.1 - 2.3e-52 177.9 0.8 2.7e-52 177.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX91480.1 - 8.4e-44 149.4 0.6 9.9e-44 149.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX91480.1 - 7.7e-12 45.5 0.7 1e-11 45.1 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91480.1 - 0.0039 16.7 0.0 0.0063 16.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KFX91480.1 - 0.0052 17.0 0.4 0.11 12.7 0.2 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HATPase_c PF02518.26 KFX91480.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.19 KFX91480.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_Tnp_Tc5 PF03221.16 KFX91493.1 - 1.3e-05 25.1 0.1 2.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KFX91493.1 - 0.0099 15.4 0.1 0.035 13.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KFX91493.1 - 0.015 15.3 0.1 0.08 12.9 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1013 PF06242.11 KFX91493.1 - 0.024 14.6 0.7 0.095 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) HTH_23 PF13384.6 KFX91493.1 - 0.038 13.8 0.0 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 KFX91493.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CENP-B_N PF04218.13 KFX91493.1 - 0.12 12.1 1.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain PAP_assoc PF03828.19 KFX91497.1 - 3.1e-19 68.9 0.1 6.8e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFX91497.1 - 1.1e-05 25.6 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFX91497.1 - 0.042 13.9 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Sel1 PF08238.12 KFX91500.1 - 5e-13 49.3 18.9 4.5e-06 27.2 0.1 7.5 7 0 0 7 7 7 5 Sel1 repeat TBPIP PF07106.13 KFX91501.1 - 3.3e-14 52.6 0.0 6.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain SHOCT PF09851.9 KFX91501.1 - 0.022 14.5 2.7 3.7 7.4 0.1 3.0 3 0 0 3 3 3 0 Short C-terminal domain DUF3106 PF11304.8 KFX91501.1 - 0.087 13.3 4.6 3.3 8.3 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) SPOC PF07744.13 KFX91504.1 - 2.3e-24 86.0 0.0 4.3e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KFX91504.1 - 1.5e-18 67.3 3.6 3.3e-18 66.2 3.6 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFX91504.1 - 2.2e-09 37.1 9.8 4e-09 36.2 9.8 1.4 1 0 0 1 1 1 1 PHD-finger SKG6 PF08693.10 KFX91504.1 - 0.0027 17.1 3.2 0.0061 16.0 3.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_Coat_B PF05356.11 KFX91504.1 - 0.12 12.3 0.6 0.28 11.1 0.6 1.5 1 0 0 1 1 1 0 Phage Coat protein B PHD_2 PF13831.6 KFX91504.1 - 1.1 8.9 4.8 2 8.0 4.8 1.5 1 0 0 1 1 1 0 PHD-finger Kelch_5 PF13854.6 KFX91504.1 - 1.1 9.3 3.8 8.7 6.5 0.4 3.4 3 0 0 3 3 3 0 Kelch motif MGC-24 PF05283.11 KFX91504.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.8 3 1 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-C2H2_jaz PF12171.8 KFX91505.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX91505.1 - 0.00047 20.4 0.1 0.00082 19.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CENP-Q PF13094.6 KFX91505.1 - 0.0033 17.7 11.7 0.0033 17.7 11.7 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-C2H2_2 PF12756.7 KFX91505.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AbiH PF14253.6 KFX91505.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH RNA_pol_3_Rpc31 PF11705.8 KFX91505.1 - 9.9 6.3 29.3 9.2 6.5 1.3 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FF PF01846.19 KFX91506.1 - 6.1e-10 39.1 1.9 3.5e-08 33.5 0.0 2.9 2 0 0 2 2 2 1 FF domain WW PF00397.26 KFX91506.1 - 8.8e-09 35.3 4.2 8.8e-09 35.3 4.2 1.8 2 0 0 2 2 2 1 WW domain Di19_C PF14571.6 KFX91506.1 - 0.021 15.3 0.2 0.021 15.3 0.2 3.1 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DUF5641 PF18701.1 KFX91506.1 - 0.093 12.9 3.0 0.1 12.8 1.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Proteasome PF00227.26 KFX91507.1 - 1.1e-59 201.2 0.2 1.3e-59 200.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX91507.1 - 3.2e-13 49.1 0.1 8.9e-13 47.7 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 KFX91507.1 - 0.0085 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF5624 PF18538.1 KFX91507.1 - 0.096 12.8 0.4 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) PAP2 PF01569.21 KFX91508.1 - 4.7e-24 84.7 1.1 4.7e-24 84.7 1.1 1.6 2 1 0 2 2 2 1 PAP2 superfamily RseC_MucC PF04246.12 KFX91508.1 - 1.4 8.9 5.4 0.54 10.2 0.4 2.6 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Med7 PF05983.11 KFX91509.1 - 5.9e-68 228.7 0.1 7.8e-68 228.3 0.1 1.2 1 0 0 1 1 1 1 MED7 protein DUF747 PF05346.11 KFX91510.1 - 1.2e-117 393.0 4.4 1.8e-117 392.3 4.4 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_methylase PF00145.17 KFX91510.1 - 9.7e-47 159.9 0.0 7.7e-46 157.0 0.0 2.5 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KFX91510.1 - 2.6e-22 79.0 0.0 1.6e-10 40.9 0.0 3.3 3 0 0 3 3 3 2 BAH domain Caveolin PF01146.17 KFX91510.1 - 0.068 13.1 0.3 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 Caveolin F-box-like PF12937.7 KFX91511.1 - 0.0023 17.8 0.5 0.0023 17.8 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFX91511.1 - 0.0024 17.7 0.1 0.0024 17.7 0.1 1.9 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.25 KFX91516.1 - 0.00063 19.2 0.1 0.00074 19.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFX91516.1 - 0.0046 16.3 0.3 0.0063 15.9 0.2 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFX91516.1 - 0.0053 16.1 0.0 0.0054 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX91516.1 - 0.021 14.7 0.5 0.03 14.2 0.5 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1192 PF06698.11 KFX91516.1 - 0.14 12.2 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) EcKinase PF02958.20 KFX91516.1 - 0.21 10.9 0.1 0.27 10.5 0.1 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase MIP PF00230.20 KFX91517.1 - 1.4e-45 155.8 10.9 1.7e-45 155.5 10.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein AAA_33 PF13671.6 KFX91518.1 - 1.4e-11 44.7 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX91518.1 - 5.7e-09 35.5 0.0 1e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KFX91518.1 - 9.1e-05 23.0 0.0 0.00025 21.6 0.0 1.8 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFX91518.1 - 0.0015 19.0 0.0 0.0032 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KFX91518.1 - 0.0033 17.6 0.0 0.0041 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.6 KFX91518.1 - 0.0061 16.8 0.0 0.0073 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFX91518.1 - 0.0062 16.4 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CoaE PF01121.20 KFX91518.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase dNK PF01712.19 KFX91518.1 - 0.022 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA PF00004.29 KFX91518.1 - 0.03 14.7 0.0 0.073 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KFX91518.1 - 0.036 14.2 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family KTI12 PF08433.10 KFX91518.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 KFX91518.1 - 0.095 12.4 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 KFX91518.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 KFX91518.1 - 0.12 12.7 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ADK PF00406.22 KFX91518.1 - 0.16 12.0 0.0 0.35 11.0 0.0 1.6 1 1 1 2 2 2 0 Adenylate kinase TauD PF02668.16 KFX91519.1 - 4.6e-36 125.0 0.1 6.8e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KFX91520.1 - 3e-13 49.4 27.3 3e-13 49.4 27.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFX91520.1 - 6.6e-09 35.7 4.5 1.6e-08 34.4 4.5 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KFX91520.1 - 0.00034 19.6 4.7 0.00034 19.6 4.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3487 PF11990.8 KFX91521.1 - 0.0025 17.7 0.6 0.012 15.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3487) DUF4064 PF13273.6 KFX91521.1 - 3.7 7.9 11.4 0.077 13.3 1.6 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Ribosomal_L2_C PF03947.18 KFX91523.1 - 1.2e-50 170.9 3.3 2.3e-50 170.0 2.6 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFX91523.1 - 5.7e-25 87.1 0.2 1.6e-24 85.6 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 KFX91524.1 - 3.3e-45 152.9 0.1 6.9e-44 148.6 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX91524.1 - 1.3e-36 125.3 0.0 2.2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.13 KFX91525.1 - 3.7e-33 114.1 3.5 4e-33 114.0 2.3 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.11 KFX91526.1 - 8.2e-47 159.1 0.2 8.2e-47 159.1 0.2 3.8 3 1 0 3 3 3 1 RXT2-like, N-terminal Chondroitinas_B PF14592.6 KFX91526.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Chondroitinase B Gryzun PF07919.12 KFX91527.1 - 2.7e-212 706.7 0.0 3.2e-212 706.5 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KFX91527.1 - 1.5e-24 87.0 0.4 2.1e-24 86.5 0.4 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 KFX91527.1 - 0.0053 16.7 0.3 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.7 KFX91528.1 - 8.1e-12 46.2 2.1 1.1e-11 45.7 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX91528.1 - 0.004 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RTT107_BRCT_5 PF16770.5 KFX91529.1 - 4e-30 103.6 0.0 3e-26 91.2 0.0 3.9 4 1 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFX91529.1 - 2.4e-29 101.1 0.2 3.4e-18 65.3 0.1 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KFX91529.1 - 1.2e-27 96.2 0.0 3.6e-05 24.1 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFX91529.1 - 1.3e-27 95.9 0.0 1.6e-08 34.8 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFX91529.1 - 9.7e-13 48.2 0.2 5.4e-05 23.4 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain ESCRT-II PF05871.12 KFX91530.1 - 2.9e-54 183.1 0.6 3.8e-54 182.7 0.6 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit NARP1 PF12569.8 KFX91531.1 - 1.2e-196 654.7 27.3 5.9e-195 649.1 21.7 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KFX91531.1 - 5.5e-15 55.7 27.2 0.0051 17.4 0.1 9.2 8 2 2 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFX91531.1 - 1.2e-12 48.1 35.6 0.00054 20.4 0.1 7.5 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX91531.1 - 2.5e-12 46.5 33.1 0.0048 17.6 0.0 11.7 7 4 6 13 13 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX91531.1 - 2.5e-12 46.3 4.7 6.1e-06 25.8 0.1 5.4 5 0 0 5 5 4 2 TPR repeat TPR_2 PF07719.17 KFX91531.1 - 1.9e-11 43.2 38.2 9.9e-05 22.2 0.1 10.8 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFX91531.1 - 2.3e-11 43.2 11.3 0.00027 21.1 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFX91531.1 - 2.7e-10 40.3 3.7 0.0013 18.8 0.2 5.3 5 1 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX91531.1 - 5.3e-10 39.4 20.5 0.00012 22.2 0.8 5.6 4 3 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFX91531.1 - 2.3e-09 36.7 31.2 2.3e-06 27.2 0.2 8.3 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX91531.1 - 2.9e-08 33.3 31.3 9.4e-05 22.3 0.1 8.1 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX91531.1 - 2.5e-07 30.9 23.0 0.52 10.6 2.7 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat Sel1 PF08238.12 KFX91531.1 - 0.035 14.8 3.0 6.7 7.5 0.9 3.6 2 0 0 2 2 2 0 Sel1 repeat LANC_like PF05147.13 KFX91531.1 - 0.037 12.6 0.6 0.12 10.9 0.3 1.7 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein TPR_3 PF07720.12 KFX91531.1 - 0.037 14.0 4.4 0.14 12.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFX91531.1 - 0.062 13.4 11.4 8.6 6.5 0.1 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 KFX91531.1 - 0.14 12.2 17.1 9.1 6.6 0.1 6.9 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX91531.1 - 0.17 12.6 11.6 6 7.8 1.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_int_SAM_1 PF02899.17 KFX91531.1 - 0.23 11.8 2.2 0.86 9.9 0.2 3.0 3 0 0 3 3 2 0 Phage integrase, N-terminal SAM-like domain TPR_6 PF13174.6 KFX91531.1 - 0.34 11.6 31.6 5.6 7.8 0.0 9.4 10 0 0 10 10 8 0 Tetratricopeptide repeat Vps5 PF09325.10 KFX91531.1 - 4.5 6.7 9.0 0.33 10.5 0.1 3.4 4 0 0 4 4 4 0 Vps5 C terminal like Homoserine_dh PF00742.19 KFX91532.1 - 8.9e-52 175.5 0.0 1.2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KFX91532.1 - 8.1e-19 68.4 0.0 1.3e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX91532.1 - 0.065 13.5 1.1 0.2 11.9 1.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_4 PF02390.17 KFX91534.1 - 4.8e-56 188.9 0.0 6e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KFX91534.1 - 2.6e-05 24.9 0.0 8.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91534.1 - 0.00038 21.2 0.0 0.00074 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX91534.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFX91534.1 - 0.0021 18.1 0.0 0.0069 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91534.1 - 0.018 14.9 0.0 0.037 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFX91534.1 - 0.022 15.4 0.0 0.095 13.4 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain PXA PF02194.15 KFX91535.1 - 9.1e-49 165.9 1.1 5e-48 163.5 1.1 2.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KFX91535.1 - 4.2e-28 98.2 0.1 1.4e-27 96.5 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFX91535.1 - 4.1e-20 71.9 0.5 1.2e-19 70.3 0.5 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KFX91535.1 - 1.7e-10 41.2 0.0 5.2e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain CPDase PF07823.11 KFX91535.1 - 0.068 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF2964 PF11177.8 KFX91535.1 - 2.6 8.3 6.4 0.7 10.1 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) RRM_1 PF00076.22 KFX91536.1 - 6.1e-12 45.2 0.2 1.4e-05 24.8 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX91536.1 - 0.013 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KFX91536.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Tub_N PF16322.5 KFX91542.1 - 0.0085 16.5 4.6 0.011 16.2 4.6 1.2 1 0 0 1 1 1 1 Tubby N-terminal FSAP_sig_propep PF03032.15 KFX91542.1 - 0.19 11.8 5.7 0.3 11.1 5.7 1.2 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide RRM_1 PF00076.22 KFX91543.1 - 9.5e-39 131.1 0.1 1.2e-12 47.5 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX91543.1 - 9.2e-14 51.1 0.0 0.0084 15.9 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 KFX91543.1 - 6.8e-09 35.3 4.8 6.8e-09 35.3 4.8 3.6 3 0 0 3 3 3 1 Putative RRM domain DUF4523 PF15023.6 KFX91543.1 - 2.1e-05 24.4 0.0 0.045 13.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 KFX91543.1 - 3.4e-05 23.9 0.0 0.22 11.7 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KFX91543.1 - 0.0016 18.5 0.1 0.22 11.6 0.1 2.6 2 0 0 2 2 2 1 RNA binding motif AMP-binding PF00501.28 KFX91561.1 - 4.5e-33 114.5 0.1 6e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX91561.1 - 2.5e-09 38.0 0.0 1e-07 32.8 0.0 2.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_trans_N PF14510.6 KFX91561.1 - 0.11 13.1 0.2 0.3 11.7 0.2 1.7 1 0 0 1 1 1 0 ABC-transporter N-terminal Zn_clus PF00172.18 KFX91576.1 - 8.8e-10 38.6 11.7 1.5e-09 37.8 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX91576.1 - 3.3e-06 26.3 0.2 8.5e-06 25.0 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid6H PF17389.2 KFX91577.1 - 2.5e-115 385.4 0.0 3.2e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KFX91577.1 - 7.5e-56 188.6 0.0 1e-54 184.9 0.0 2.5 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KFX91577.1 - 1e-28 99.3 0.0 1.9e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KFX91577.1 - 2e-12 46.7 0.2 4.3e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_1 PF00232.18 KFX91578.1 - 9.3e-131 436.4 0.0 1.1e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sugar_tr PF00083.24 KFX91579.1 - 8e-69 232.6 27.6 9.2e-69 232.4 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91579.1 - 1.6e-13 50.3 37.1 2e-08 33.5 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.6 KFX91579.1 - 0.95 9.2 5.0 0.2 11.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Helicase_C_2 PF13307.6 KFX91584.1 - 1.4e-55 188.1 0.0 3.8e-55 186.7 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFX91584.1 - 2.4e-51 173.8 0.0 4.2e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KFX91584.1 - 0.01 15.8 0.0 5.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX91584.1 - 0.15 12.4 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Titin_Z PF09042.11 KFX91584.1 - 0.34 10.9 4.0 2.5 8.1 0.7 2.8 2 0 0 2 2 2 0 Titin Z Ribosomal_L27A PF00828.19 KFX91585.1 - 1.5e-21 77.4 0.0 2.6e-21 76.6 0.0 1.4 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 KFX91586.1 - 1.3e-41 142.8 0.0 1.1e-38 133.1 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91586.1 - 1.1e-12 47.8 0.0 8.1e-07 28.6 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX91586.1 - 0.00025 20.4 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFX91586.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFX91586.1 - 0.0092 15.9 0.0 0.072 13.0 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_7 PF13499.6 KFX91586.1 - 0.051 14.0 1.1 0.44 11.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Cnd1_N PF12922.7 KFX91587.1 - 5.3e-63 211.8 0.2 4.9e-62 208.7 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KFX91587.1 - 1e-47 162.2 3.3 2.8e-43 147.8 1.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX91587.1 - 1.5e-09 37.3 5.6 0.031 14.5 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFX91587.1 - 7.6e-09 35.8 5.1 0.00044 20.6 0.0 4.9 5 1 2 7 7 6 3 HEAT repeats HEAT_EZ PF13513.6 KFX91587.1 - 2e-05 25.0 9.7 0.13 12.8 0.1 5.9 7 0 0 7 7 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KFX91587.1 - 0.00024 21.2 0.2 0.77 10.0 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KFX91587.1 - 0.0046 16.2 1.4 0.0046 16.2 1.4 2.8 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain p450 PF00067.22 KFX91587.1 - 0.062 12.0 0.6 0.12 11.1 0.6 1.4 1 0 0 1 1 1 0 Cytochrome P450 IFN-gamma PF00714.17 KFX91587.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Interferon gamma DUF573 PF04504.14 KFX91587.1 - 0.12 13.0 0.6 3.8 8.2 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function, DUF573 VHS PF00790.19 KFX91587.1 - 0.27 11.1 1.8 2.6 7.9 0.0 3.3 3 0 0 3 3 3 0 VHS domain MAM33 PF02330.16 KFX91588.1 - 1.6e-74 250.4 5.1 1.9e-74 250.2 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 KFX91589.1 - 5.9e-47 159.2 0.2 7.1e-47 159.0 0.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_I PF00867.18 KFX91590.1 - 3.3e-24 85.1 0.1 9.1e-24 83.6 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFX91590.1 - 1.5e-20 73.6 0.0 3.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFX91590.1 - 0.0011 18.5 0.1 0.0023 17.4 0.0 1.5 2 0 0 2 2 2 1 XPG domain containing DUF3695 PF12494.8 KFX91590.1 - 0.08 12.8 0.1 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) IBR PF01485.21 KFX91591.1 - 2.4e-21 75.7 46.6 2e-11 43.9 5.2 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFX91591.1 - 0.00055 19.8 6.6 0.00055 19.8 6.6 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX91591.1 - 0.008 16.0 4.7 0.008 16.0 4.7 5.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX91591.1 - 0.013 15.9 7.3 0.013 15.9 7.3 4.1 2 1 1 3 3 3 0 Ring finger domain zf-C3HC4_4 PF15227.6 KFX91591.1 - 0.019 15.1 26.1 0.14 12.4 0.8 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFX91591.1 - 0.56 10.3 34.3 0.057 13.5 5.1 3.9 3 1 0 3 3 3 0 RING-type zinc-finger PIP5K PF01504.18 KFX91592.1 - 1.2e-100 336.3 1.4 1.3e-100 336.2 0.2 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.19 KFX91593.1 - 6.3e-27 93.8 0.8 6.3e-27 93.8 0.8 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 KFX91593.1 - 4.2 7.1 12.6 5.8 6.6 12.6 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tubulin_2 PF13809.6 KFX91594.1 - 0.095 11.9 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Tubulin like XPG_I PF00867.18 KFX91595.1 - 5.3e-32 110.0 1.1 2.8e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KFX91595.1 - 3.2e-21 75.7 0.1 5.1e-20 71.8 0.0 2.6 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFX91595.1 - 1.2e-05 25.8 0.4 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4303 PF14136.6 KFX91595.1 - 1.8 8.3 5.2 30 4.3 5.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4303) Acyl-CoA_dh_N PF02771.16 KFX91596.1 - 3.2e-24 85.8 0.6 5.9e-24 84.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX91596.1 - 1e-21 77.7 0.1 1.8e-21 76.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX91596.1 - 7.4e-17 61.3 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX91596.1 - 3.8e-05 24.0 0.1 0.0001 22.5 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 KFX91597.1 - 4.2e-50 169.0 0.0 5.5e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX91597.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KFX91597.1 - 0.077 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KFX91597.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 KFX91598.1 - 3.6e-32 111.6 0.0 7.6e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFX91598.1 - 8.9e-21 74.3 18.9 7.8e-20 71.3 12.9 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX91598.1 - 2e-20 72.9 0.0 6.3e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFX91598.1 - 0.075 13.7 0.0 0.22 12.2 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain 2-Hacid_dh_C PF02826.19 KFX91599.1 - 1.2e-52 177.9 0.0 2.3e-52 177.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX91599.1 - 2.9e-22 78.8 0.0 4.3e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX91599.1 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFX91599.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KFX91599.1 - 0.016 14.9 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFX91599.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX91599.1 - 0.13 12.4 1.5 0.55 10.3 0.2 2.5 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX91599.1 - 0.15 12.6 1.5 3 8.5 0.8 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KFX91600.1 - 9.5e-33 113.6 31.9 1.3e-32 113.1 31.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MLANA PF14991.6 KFX91607.1 - 0.026 14.8 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A zf-RING_2 PF13639.6 KFX91620.1 - 9.9e-09 35.4 1.2 1.4e-08 34.9 1.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFX91620.1 - 7e-05 23.0 2.8 0.00019 21.6 2.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFX91620.1 - 0.00017 21.5 4.0 0.00028 20.9 4.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFX91620.1 - 0.00024 21.1 0.7 0.00037 20.5 0.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KFX91620.1 - 0.00024 20.9 1.8 0.00043 20.1 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX91620.1 - 0.001 18.7 0.9 0.0016 18.1 0.9 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFX91620.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX91620.1 - 0.066 13.1 0.4 0.1 12.5 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX91620.1 - 0.11 12.4 0.4 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 KFX91620.1 - 0.14 12.6 0.1 0.14 12.6 0.1 1.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain ANAPC4_WD40 PF12894.7 KFX91621.1 - 0.11 12.9 0.0 0.51 10.7 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF908 PF06012.12 KFX91622.1 - 0.11 11.9 5.7 0.18 11.2 5.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) UDPGP PF01704.18 KFX91623.1 - 4.7e-141 470.2 0.1 5.7e-141 469.9 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Innate_immun PF12782.7 KFX91623.1 - 0.08 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Neurensin PF14927.6 KFX91624.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Neurensin DUF2721 PF11026.8 KFX91624.1 - 0.021 14.7 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Orf78 PF06024.12 KFX91624.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) adh_short PF00106.25 KFX91644.1 - 5.4e-19 68.4 0.0 7.7e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91644.1 - 2.5e-12 46.9 0.0 3.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91644.1 - 9.4e-07 28.9 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91644.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX91644.1 - 0.0089 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KFX91644.1 - 0.032 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DEAD PF00270.29 KFX91646.1 - 4.4e-44 150.3 0.1 7.6e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX91646.1 - 1.2e-26 93.2 0.0 2.1e-25 89.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX91646.1 - 7.6e-06 26.0 0.0 7.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX91646.1 - 0.12 12.6 0.2 0.35 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 KFX91646.1 - 1 9.1 11.0 2.2 8.0 11.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 KFX91646.1 - 3.7 6.2 7.5 6 5.5 7.5 1.2 1 0 0 1 1 1 0 Raftlin CDC27 PF09507.10 KFX91646.1 - 4.1 6.7 23.7 9.6 5.5 23.7 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FtsJ PF01728.19 KFX91647.1 - 7.5e-64 215.1 0.1 1.5e-63 214.1 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Acetyltransf_1 PF00583.25 KFX91648.1 - 1.5e-08 34.9 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX91648.1 - 1.4e-06 28.6 0.0 2.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX91648.1 - 2.7e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX91648.1 - 0.00081 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Peptidase_M16_C PF05193.21 KFX91656.1 - 5.3e-53 179.7 0.0 1.1e-52 178.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFX91656.1 - 1.8e-43 148.0 0.0 4.7e-42 143.5 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FHA PF00498.26 KFX91657.1 - 3.9e-14 52.8 0.0 6.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KFX91657.1 - 4.7e-13 48.6 3.7 8.7e-13 47.8 3.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFX91657.1 - 2.1e-05 24.7 10.3 3.4e-05 24.1 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KFX91657.1 - 0.0019 18.4 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KFX91657.1 - 0.0034 17.2 8.0 0.0055 16.5 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX91657.1 - 0.067 13.2 6.6 0.11 12.4 6.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX91657.1 - 0.3 11.0 8.7 0.56 10.1 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KFX91657.1 - 0.31 11.0 6.3 0.56 10.1 6.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 KFX91657.1 - 0.49 10.7 7.6 1.1 9.7 7.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain OrfB_Zn_ribbon PF07282.11 KFX91657.1 - 0.69 9.9 5.1 9.2 6.3 0.2 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-RING_UBOX PF13445.6 KFX91657.1 - 0.75 9.9 8.7 1.5 8.9 8.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 KFX91657.1 - 8.1 6.8 7.4 15 6.0 7.4 1.4 1 0 0 1 1 1 0 RING-like domain MARVEL PF01284.23 KFX91658.1 - 0.00012 22.1 8.3 0.00018 21.5 8.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain NCE101 PF11654.8 KFX91658.1 - 0.00087 18.9 1.1 0.82 9.4 0.0 2.5 2 0 0 2 2 2 2 Non-classical export protein 1 DUF2207 PF09972.9 KFX91658.1 - 0.31 9.8 4.3 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Vps16_N PF04841.13 KFX91659.1 - 4.6e-99 332.0 0.0 6.2e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFX91659.1 - 1.1e-86 290.7 0.0 1.8e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Coatomer_WDAD PF04053.14 KFX91659.1 - 0.0037 16.4 0.0 2.3 7.2 0.0 3.2 3 0 0 3 3 3 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KFX91659.1 - 0.029 14.7 0.0 0.26 11.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HD PF01966.22 KFX91665.1 - 0.00049 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 HD domain Aa_trans PF01490.18 KFX91666.1 - 1.3e-28 99.9 37.6 1.7e-28 99.5 37.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MBOAT PF03062.19 KFX91669.1 - 9.3e-37 127.2 15.8 2.5e-36 125.8 15.8 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.20 KFX91670.1 - 3.9e-142 474.5 0.1 4.8e-142 474.2 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFX91670.1 - 4.2e-17 62.4 0.0 9.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFX91670.1 - 2.3e-07 31.0 6.2 0.00013 22.0 0.0 3.9 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF3730 PF12530.8 KFX91670.1 - 4e-05 23.3 0.1 0.0019 17.8 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 KFX91670.1 - 7.4e-05 23.1 6.3 0.036 14.5 0.0 4.7 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KFX91670.1 - 0.027 15.0 0.9 78 3.9 0.0 5.3 4 2 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 KFX91670.1 - 0.037 14.3 4.4 7.9 7.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat AAA_18 PF13238.6 KFX91671.1 - 7e-06 26.6 0.1 1.6e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX91671.1 - 0.0002 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX91671.1 - 0.00069 19.8 0.2 0.0019 18.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFX91671.1 - 0.00086 19.7 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 KFX91671.1 - 0.0022 18.2 0.3 0.0072 16.5 0.1 1.9 1 1 1 2 2 2 1 Shikimate kinase DUF2075 PF09848.9 KFX91671.1 - 0.0047 16.2 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 KFX91671.1 - 0.0058 17.1 0.0 0.0078 16.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 KFX91671.1 - 0.0061 16.3 0.7 0.02 14.6 0.6 1.8 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KFX91671.1 - 0.021 14.0 0.0 0.027 13.7 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.9 KFX91671.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin2 PF13189.6 KFX91671.1 - 0.024 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_25 PF13481.6 KFX91671.1 - 0.03 13.9 0.2 0.048 13.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFX91671.1 - 0.031 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KFX91671.1 - 0.033 14.5 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX91671.1 - 0.047 13.6 1.2 0.055 13.4 0.3 1.8 2 1 0 2 2 2 0 NACHT domain Ploopntkinase3 PF18751.1 KFX91671.1 - 0.047 13.6 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_17 PF13207.6 KFX91671.1 - 0.047 14.1 0.2 0.65 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFX91671.1 - 0.073 12.3 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin dNK PF01712.19 KFX91671.1 - 0.077 12.8 0.1 0.19 11.6 0.1 1.7 1 1 1 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 KFX91671.1 - 0.091 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 KFX91671.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFX91671.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 KFX91671.1 - 0.17 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.15 KFX91671.1 - 0.22 11.4 0.2 0.38 10.7 0.2 1.3 1 0 0 1 1 1 0 NTPase Metallophos PF00149.28 KFX91686.1 - 1.1e-18 68.5 0.0 1.6e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX91686.1 - 1.6e-05 25.2 0.0 0.00021 21.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NUDIX PF00293.28 KFX91687.1 - 8.5e-17 61.4 1.1 1e-16 61.2 1.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KFX91687.1 - 0.0043 16.7 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase Mononeg_mRNAcap PF14318.6 KFX91694.1 - 0.11 11.7 1.4 0.17 11.1 1.4 1.4 1 1 0 1 1 1 0 Mononegavirales mRNA-capping region V APH PF01636.23 KFX91695.1 - 1.5e-06 28.4 0.0 5.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX91695.1 - 2.3e-05 24.1 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFX91695.1 - 0.0061 16.0 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain adh_short PF00106.25 KFX91696.1 - 4.9e-32 111.0 0.1 7.6e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91696.1 - 9.5e-22 77.7 0.1 1.2e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91696.1 - 8.5e-09 35.6 0.2 1.5e-08 34.8 0.1 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFX91696.1 - 0.00011 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX91696.1 - 0.041 12.9 0.2 0.1 11.6 0.2 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.18 KFX91697.1 - 7.8e-07 29.1 14.4 7.8e-07 29.1 14.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFX91697.1 - 2.8 8.6 7.8 0.16 12.5 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type IDO PF01231.18 KFX91698.1 - 5.8e-13 48.4 0.0 2.3e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.28 KFX91698.1 - 1e-11 44.8 0.0 3.3e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 KFX91698.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFX91698.1 - 9.3e-09 35.9 0.0 2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipase_GDSL_2 PF13472.6 KFX91699.1 - 6.7e-09 36.4 0.3 8.9e-09 36.0 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sacchrp_dh_NADP PF03435.18 KFX91700.1 - 4.9e-16 59.2 0.1 9.7e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFX91701.1 - 1.8e-11 44.0 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX91701.1 - 2.2e-07 31.0 0.1 7.3e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX91701.1 - 8.1e-06 25.5 0.1 1.8e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX91701.1 - 1.5e-05 24.2 0.0 2.8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFX91701.1 - 3.5e-05 23.5 0.1 5.2e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KFX91701.1 - 0.00014 21.3 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX91701.1 - 0.0057 16.2 0.1 0.024 14.2 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.15 KFX91701.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX91701.1 - 0.17 11.0 0.0 1.7 7.7 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain DUF2873 PF11395.8 KFX91702.1 - 0.16 11.9 2.2 0.75 9.7 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) PMP1_2 PF08114.11 KFX91702.1 - 4.4 7.1 10.4 0.23 11.2 1.3 3.1 2 1 1 3 3 3 0 ATPase proteolipid family MFS_1 PF07690.16 KFX91703.1 - 9e-17 61.0 44.3 9e-17 61.0 44.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4383 PF14325.6 KFX91703.1 - 0.001 19.4 2.2 0.001 19.4 2.2 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4383) UPF0093 PF03653.13 KFX91703.1 - 0.0046 17.2 1.4 0.067 13.4 2.8 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) Aldedh PF00171.22 KFX91704.1 - 1.7e-116 389.5 0.3 2.5e-116 388.9 0.3 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_3 PF03447.16 KFX91704.1 - 0.057 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.18 KFX91705.1 - 6.9e-08 32.5 9.2 1.4e-07 31.5 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX91705.1 - 4.9e-07 28.9 1.5 9.4e-07 28.0 1.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 KFX91705.1 - 0.021 14.6 2.2 0.05 13.4 2.2 1.6 1 0 0 1 1 1 0 Integrin plexin domain MFS_1 PF07690.16 KFX91710.1 - 2.8e-21 75.8 52.6 2.8e-18 66.0 37.9 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily PPR_2 PF13041.6 KFX91711.1 - 6.3e-11 42.3 0.3 0.52 10.5 0.0 6.5 7 0 0 7 7 7 4 PPR repeat family PPR_3 PF13812.6 KFX91711.1 - 2e-08 34.1 0.0 0.067 13.3 0.0 4.6 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KFX91711.1 - 0.00082 19.5 10.3 1.2 9.5 0.0 6.6 9 0 0 9 9 9 2 PPR repeat ATP13 PF12921.7 KFX91711.1 - 0.0067 16.3 0.3 4.9 7.1 0.1 3.1 2 1 1 3 3 3 2 Mitochondrial ATPase expression PPR_long PF17177.4 KFX91711.1 - 0.01 15.2 1.3 0.67 9.3 0.0 3.3 2 2 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP Fungal_trans_2 PF11951.8 KFX91717.1 - 1.4e-18 66.9 4.2 3.5e-14 52.4 1.7 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Peptidase_C48 PF02902.19 KFX91720.1 - 1.4e-05 25.0 0.0 3.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-HC5HC2H_2 PF13832.6 KFX91720.1 - 0.032 14.4 1.1 0.055 13.6 1.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2318 PF10080.9 KFX91720.1 - 0.11 12.6 0.4 0.19 11.9 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) PHD PF00628.29 KFX91720.1 - 0.14 12.1 4.8 0.28 11.1 4.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KFX91720.1 - 0.17 11.8 3.1 0.28 11.1 3.1 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon AT_hook PF02178.19 KFX91720.1 - 0.84 9.7 9.9 0.19 11.7 5.0 2.7 2 0 0 2 2 2 0 AT hook motif FAD_binding_3 PF01494.19 KFX91722.1 - 2e-19 70.0 0.0 2.4e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX91722.1 - 1.1e-13 51.5 1.6 9.1e-07 28.8 0.2 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91722.1 - 2.1e-09 37.0 0.3 4.6e-07 29.3 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX91722.1 - 7.6e-08 32.5 0.1 1.8e-07 31.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX91722.1 - 2.8e-07 29.6 0.0 2.6e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFX91722.1 - 2.3e-06 27.0 0.0 4.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX91722.1 - 6.4e-06 25.6 0.0 6.6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX91722.1 - 2.3e-05 23.9 0.0 0.0065 15.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KFX91722.1 - 4.4e-05 22.5 0.0 0.067 12.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KFX91722.1 - 7.8e-05 23.2 0.0 0.00058 20.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX91722.1 - 0.00037 20.0 0.2 0.0015 18.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX91722.1 - 0.00084 18.5 0.1 0.0049 16.0 0.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KFX91722.1 - 0.0019 17.4 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KFX91722.1 - 0.0036 16.6 0.4 0.0059 15.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFX91722.1 - 0.0038 16.5 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Glu_dehyd_C PF16912.5 KFX91722.1 - 0.0054 16.3 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 KFX91722.1 - 0.026 14.4 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFX91722.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KFX91722.1 - 0.062 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFX91722.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX91722.1 - 0.17 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFX91722.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UBA PF00627.31 KFX91730.1 - 1.9e-14 53.2 0.5 2.8e-14 52.7 0.5 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Goodbye PF17109.5 KFX91731.1 - 4.9e-36 123.8 0.0 1.1e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KFX91731.1 - 2.4e-09 37.3 0.0 6.2e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX91731.1 - 2.4e-07 31.3 0.1 1.7e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX91731.1 - 9.9e-05 22.6 0.0 0.00034 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX91731.1 - 0.0041 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KFX91731.1 - 0.018 15.0 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFX91731.1 - 0.036 14.5 0.0 0.17 12.3 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PS_Dcarbxylase PF02666.15 KFX91731.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase AAA_19 PF13245.6 KFX91731.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.19 KFX91732.1 - 3.6e-50 171.0 0.0 4.7e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX91732.1 - 1.1e-32 113.5 0.0 1.8e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX91732.1 - 4.8e-06 25.9 0.9 0.071 12.2 1.2 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFX91732.1 - 0.00047 19.5 0.1 0.0011 18.3 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KFX91732.1 - 0.0027 16.8 0.0 0.0069 15.5 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KFX91732.1 - 0.017 14.7 1.7 0.085 12.4 2.1 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91732.1 - 0.019 14.2 0.0 0.072 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91732.1 - 0.02 14.2 0.0 4.2 6.5 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX91732.1 - 0.042 14.1 0.4 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KFX91732.1 - 0.2 12.0 0.2 0.87 9.9 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain Catalase PF00199.19 KFX91733.1 - 9.5e-165 548.3 0.5 1.2e-164 548.1 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFX91733.1 - 8.2e-13 48.4 0.0 1.9e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive HEAT_2 PF13646.6 KFX91733.1 - 0.072 13.5 0.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Methyltransf_PK PF05891.12 KFX91733.1 - 0.14 11.7 0.0 16 4.9 0.0 2.3 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase CAP_N PF01213.19 KFX91734.1 - 0.054 13.0 3.5 0.06 12.8 3.5 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SKG6 PF08693.10 KFX91735.1 - 0.0031 16.9 0.6 0.0062 15.9 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KFX91735.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM132D_C PF15706.5 KFX91735.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 KFX91735.1 - 0.17 12.8 0.0 0.33 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 KFX91735.1 - 0.94 9.5 3.8 3 7.9 3.8 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Glyco_hydro_11 PF00457.17 KFX91736.1 - 2.4e-60 203.2 11.0 2.7e-60 203.0 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Na_H_Exchanger PF00999.21 KFX91738.1 - 4e-73 246.4 36.8 5.2e-73 246.0 36.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5345 PF17280.2 KFX91738.1 - 1.6 8.7 4.7 0.83 9.7 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) MFS_2 PF13347.6 KFX91739.1 - 2e-07 29.9 3.1 2e-07 29.9 3.1 3.0 3 1 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 KFX91739.1 - 1.4e-06 27.6 1.4 2.5e-06 26.7 1.4 1.4 1 0 0 1 1 1 1 PUCC protein PKD PF00801.20 KFX91740.1 - 0.53 10.2 9.1 3.9 7.4 1.3 2.9 1 1 2 3 3 3 0 PKD domain Aldedh PF00171.22 KFX91741.1 - 3.6e-177 589.5 0.6 4.7e-177 589.1 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_PK PF05891.12 KFX91741.1 - 3.2e-73 245.9 0.0 5.4e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase LCD1 PF09798.9 KFX91742.1 - 0.016 13.7 0.4 0.016 13.7 0.4 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein FA_desaturase PF00487.24 KFX91745.1 - 9.5e-19 68.2 13.8 9.5e-19 68.2 13.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFX91745.1 - 1.5e-16 60.3 0.3 3.9e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 KFX91745.1 - 0.11 12.1 0.4 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) MOSC PF03473.17 KFX91746.1 - 3.5e-26 91.8 0.0 8.8e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KFX91746.1 - 3.7e-12 46.2 0.0 6.6e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain 4HBT PF03061.22 KFX91747.1 - 1.3e-13 51.1 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFX91747.1 - 1.6e-05 25.3 0.0 2.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HupF_HypC PF01455.18 KFX91747.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family SMC_N PF02463.19 KFX91748.1 - 2.7e-67 226.4 13.0 1.4e-66 224.1 13.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX91748.1 - 2e-21 76.5 1.2 9.9e-21 74.2 0.3 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFX91748.1 - 1.7e-13 51.6 7.8 1.7e-13 51.6 7.8 6.7 2 2 3 5 5 1 1 AAA domain AAA_21 PF13304.6 KFX91748.1 - 2.5e-10 40.7 4.9 0.00014 21.8 0.1 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX91748.1 - 9e-09 35.5 5.1 9e-09 35.5 5.1 4.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 KFX91748.1 - 0.00013 21.6 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.6 KFX91748.1 - 0.00048 19.8 7.4 0.00048 19.8 7.4 6.5 2 2 3 5 5 4 1 Ciliary protein causing Leber congenital amaurosis disease XhlA PF10779.9 KFX91748.1 - 0.0061 16.7 4.1 0.0061 16.7 4.1 8.3 8 2 1 10 10 9 2 Haemolysin XhlA HIP1_clath_bdg PF16515.5 KFX91748.1 - 0.0086 16.7 8.2 0.0086 16.7 8.2 9.6 3 2 4 8 8 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 KFX91748.1 - 0.15 12.5 0.0 0.15 12.5 0.0 6.2 4 2 0 4 4 2 0 ABC transporter NRN1 PF15056.6 KFX91748.1 - 0.73 10.0 3.1 1.3 9.2 0.4 2.9 2 0 0 2 2 2 0 Neuritin protein family DUF2015 PF09435.10 KFX91748.1 - 1.6 8.6 6.1 0.61 10.0 0.3 3.2 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2015) NDT80_PhoG PF05224.12 KFX91751.1 - 2.5e-42 145.2 0.0 4.8e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pyr_redox_2 PF07992.14 KFX91752.1 - 2.6e-34 118.8 0.3 3.3e-34 118.5 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91752.1 - 4.8e-12 45.8 0.9 6.9e-12 45.2 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX91752.1 - 1.2e-09 38.6 1.0 6e-09 36.4 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX91752.1 - 0.0068 15.6 0.3 0.011 14.9 0.3 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFX91752.1 - 0.011 14.4 2.0 5.8 5.5 0.1 3.4 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_7 PF13241.6 KFX91752.1 - 0.075 13.5 0.7 0.52 10.8 0.5 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 KFX91752.1 - 0.1 11.4 4.1 0.81 8.5 0.2 2.2 1 1 1 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 KFX91752.1 - 0.29 10.2 0.0 0.29 10.2 0.0 2.5 2 1 1 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFX91752.1 - 0.32 10.0 4.4 11 5.0 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 KFX91752.1 - 0.79 9.2 11.6 7.6 6.0 0.4 3.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase MetallophosN PF16371.5 KFX91752.1 - 1.1 9.5 3.9 0.61 10.4 0.2 2.3 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase RTA1 PF04479.13 KFX91753.1 - 9e-41 139.8 7.5 1.4e-40 139.1 7.5 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF4325 PF14213.6 KFX91753.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Peptidase_C34 PF05413.11 KFX91753.1 - 0.13 12.6 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase RNase_H PF00075.24 KFX91754.1 - 7.3e-19 68.4 0.0 1.5e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 RNase H Zn_clus PF00172.18 KFX91754.1 - 2.5e-07 30.7 13.0 4.7e-07 29.8 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_3 PF13456.6 KFX91754.1 - 0.0073 16.1 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase-like DUF3666 PF12408.8 KFX91754.1 - 0.028 13.6 0.5 0.11 11.7 0.1 2.2 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase zf-C2H2_2 PF12756.7 KFX91755.1 - 0.34 11.3 2.8 2.5 8.5 0.7 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFX91755.1 - 0.37 11.8 13.4 2.7 9.1 0.2 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger LIM PF00412.22 KFX91755.1 - 0.4 10.9 4.4 2.7 8.3 0.7 2.4 2 0 0 2 2 2 0 LIM domain BRO1 PF03097.18 KFX91757.1 - 6e-132 440.1 2.3 6e-132 440.1 2.3 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFX91757.1 - 3e-77 259.8 13.4 3e-77 259.8 13.4 2.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Lon_C PF05362.13 KFX91757.1 - 1.6e-61 207.4 0.0 3.7e-61 206.2 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFX91757.1 - 2.7e-33 115.6 2.6 3.6e-33 115.2 0.0 2.5 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFX91757.1 - 4.8e-22 78.8 0.0 1.5e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX91757.1 - 1.3e-06 28.5 0.0 3.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX91757.1 - 4.7e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KFX91757.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KFX91757.1 - 7.8e-05 23.0 0.2 0.0011 19.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KFX91757.1 - 8.7e-05 21.6 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KFX91757.1 - 0.00016 21.5 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX91757.1 - 0.00045 20.6 1.1 0.0032 17.9 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX91757.1 - 0.0061 16.5 0.6 0.3 11.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 KFX91757.1 - 0.022 14.8 0.0 0.069 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX91757.1 - 0.033 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX91757.1 - 0.11 12.9 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KFX91757.1 - 0.16 12.5 0.0 0.16 12.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain GRP PF07172.11 KFX91757.1 - 0.58 10.9 6.8 2.1 9.1 6.8 1.9 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.25 KFX91758.1 - 1.3e-11 44.4 0.0 2e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91758.1 - 7.6e-10 38.5 0.0 9.2e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PALP PF00291.25 KFX91765.1 - 2.2e-25 89.7 1.2 2.4e-25 89.6 1.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF572 PF04502.13 KFX91766.1 - 4.2e-43 148.2 0.0 4.8e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C2H2_2 PF12756.7 KFX91767.1 - 0.12 12.7 0.3 0.21 11.9 0.3 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KFX91767.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PHD PF00628.29 KFX91772.1 - 1.2e-05 25.1 11.6 3.7e-05 23.5 11.6 1.9 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KFX91772.1 - 0.076 13.2 7.5 0.21 11.8 7.5 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain PXA PF02194.15 KFX91775.1 - 0.00045 20.2 0.3 0.00077 19.5 0.1 1.4 2 0 0 2 2 2 1 PXA domain DprA_WH PF17782.1 KFX91775.1 - 3.6 7.8 8.2 8 6.7 8.2 1.9 1 1 0 1 1 1 0 DprA winged helix domain DLH PF01738.18 KFX91783.1 - 1.7e-14 53.9 0.0 2.2e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 KFX91783.1 - 0.16 11.8 0.0 1.4 8.8 0.0 1.9 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans_2 PF11951.8 KFX91784.1 - 1.5e-14 53.7 0.6 2.7e-14 52.8 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91784.1 - 8.3e-07 29.0 11.6 1.4e-06 28.3 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KFX91784.1 - 1.1 9.6 4.0 2.8 8.3 4.0 1.6 1 0 0 1 1 1 0 Opy2 protein Pterin_bind PF00809.22 KFX91798.1 - 1.8e-75 253.8 0.0 2.3e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KFX91798.1 - 7.4e-36 123.1 0.0 2e-35 121.6 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Mit_KHE1 PF10173.9 KFX91800.1 - 2.4e-60 203.9 1.0 2.7e-60 203.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SNF2_N PF00176.23 KFX91801.1 - 3.3e-64 216.8 0.3 7.5e-64 215.6 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX91801.1 - 9.3e-22 77.5 0.0 2.5e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX91801.1 - 6.5e-08 32.8 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX91801.1 - 5.8e-05 22.9 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFX91801.1 - 0.00011 21.5 0.0 0.068 12.3 0.0 2.9 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KFX91801.1 - 0.00028 20.2 0.0 0.00056 19.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Abhydrolase_1 PF00561.20 KFX91802.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.24 KFX91803.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase EptA_B_N PF08019.12 KFX91803.1 - 0.079 12.8 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB NAD_binding_4 PF07993.12 KFX91804.1 - 1.6e-72 243.8 0.0 2.3e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KFX91804.1 - 3.6e-71 240.0 0.0 6.2e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KFX91804.1 - 1e-10 41.5 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX91804.1 - 3e-08 33.9 0.0 6.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KFX91804.1 - 4.4e-08 32.5 0.0 1.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KFX91804.1 - 0.00085 20.3 0.1 0.0061 17.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KFX91804.1 - 0.00092 19.1 0.2 0.0045 16.9 0.2 2.2 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX91804.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFX91804.1 - 0.03 13.5 0.0 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAR2 PF05282.11 KFX91804.1 - 0.1 12.0 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAR2 protein RmlD_sub_bind PF04321.17 KFX91804.1 - 0.12 11.5 0.1 0.84 8.7 0.1 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain Cupin_8 PF13621.6 KFX91808.1 - 3.4e-32 112.1 0.0 5.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFX91808.1 - 4.7e-08 32.9 0.0 8.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Ribul_P_3_epim PF00834.19 KFX91808.1 - 0.0032 16.9 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjC PF02373.22 KFX91808.1 - 0.012 16.0 0.0 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFX91808.1 - 0.082 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Cupin domain DUF1180 PF06679.12 KFX91809.1 - 0.72 10.3 5.5 0.77 10.2 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FAD_binding_4 PF01565.23 KFX91810.1 - 1.8e-23 82.8 3.3 3.1e-23 82.1 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX91810.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Adap_comp_sub PF00928.21 KFX91818.1 - 1.7e-75 253.8 0.0 2.5e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFX91818.1 - 2e-09 37.5 0.3 3.6e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KFX91818.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Opi1 PF08618.10 KFX91819.1 - 2e-39 136.0 27.2 3.4e-31 108.9 3.9 4.2 3 1 1 4 4 4 3 Transcription factor Opi1 Exc PF07825.11 KFX91819.1 - 0.0042 17.0 0.6 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 Excisionase-like protein Myb_DNA-bind_6 PF13921.6 KFX91823.1 - 0.00095 19.4 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX91823.1 - 0.0074 16.5 1.2 0.04 14.1 1.2 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFX91823.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUP PF00674.18 KFX91823.1 - 0.079 13.1 0.4 0.22 11.7 0.4 1.7 1 1 0 1 1 1 0 DUP family Myb_DNA-bind_3 PF12776.7 KFX91823.1 - 0.14 13.2 0.1 0.24 12.4 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Atg29_N PF18388.1 KFX91823.1 - 0.15 11.9 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Atg29 N-terminal domain Dopey_N PF04118.14 KFX91829.1 - 0.018 14.2 0.1 0.17 11.0 0.0 2.1 2 0 0 2 2 2 0 Dopey, N-terminal FAA_hydro_N_2 PF18288.1 KFX91829.1 - 0.33 11.4 2.4 6.3 7.3 0.1 3.4 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Cluap1 PF10234.9 KFX91829.1 - 1.5 8.1 8.5 0.24 10.7 4.5 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Methyltransf_23 PF13489.6 KFX91830.1 - 6.8e-21 74.8 0.0 1.3e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PLDc_2 PF13091.6 KFX91830.1 - 1.1e-15 57.7 0.1 2.4e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Methyltransf_25 PF13649.6 KFX91830.1 - 6.9e-13 49.1 0.0 2.9e-12 47.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX91830.1 - 6.3e-10 39.6 0.0 2.3e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91830.1 - 7.4e-08 33.0 0.0 2.9e-07 31.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91830.1 - 4.7e-07 29.7 0.0 7.1e-06 25.9 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX91830.1 - 6.1e-06 25.7 0.0 4.6e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PLDc PF00614.22 KFX91830.1 - 0.0013 18.8 0.1 0.43 10.8 0.1 2.8 2 0 0 2 2 2 1 Phospholipase D Active site motif PrmA PF06325.13 KFX91830.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFX91830.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KFX91830.1 - 0.036 13.8 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KFX91830.1 - 0.04 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KFX91830.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_60s PF00428.19 KFX91830.1 - 0.15 12.7 0.9 0.39 11.3 0.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RTA1 PF04479.13 KFX91831.1 - 1.8e-73 246.6 5.5 2.7e-73 246.0 5.5 1.3 1 0 0 1 1 1 1 RTA1 like protein ATP1G1_PLM_MAT8 PF02038.16 KFX91831.1 - 0.0012 18.3 0.2 0.0012 18.3 0.2 2.4 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family HisKA_4TM PF16926.5 KFX91831.1 - 0.073 12.6 1.4 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase Sugar_tr PF00083.24 KFX91832.1 - 2.6e-102 343.0 22.5 3.2e-102 342.7 22.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91832.1 - 8.8e-26 90.6 39.4 1.6e-18 66.8 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 KFX91832.1 - 2.7e-05 24.9 0.0 6.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX91832.1 - 0.00025 21.5 0.0 0.00051 20.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MatC_N PF07158.11 KFX91832.1 - 1.1 9.3 10.1 0.78 9.8 6.0 2.7 3 0 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus Lig_chan PF00060.26 KFX91832.1 - 8.3 6.2 5.8 20 5.0 0.2 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Acyl_transf_3 PF01757.22 KFX91833.1 - 5.2e-17 61.9 17.2 7.1e-17 61.5 17.2 1.1 1 0 0 1 1 1 1 Acyltransferase family Alpha-L-AF_C PF06964.12 KFX91834.1 - 2.1e-29 102.8 0.2 3e-29 102.3 0.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_30C PF17189.4 KFX91834.1 - 0.071 13.3 0.2 0.31 11.3 0.2 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Fungal_trans_2 PF11951.8 KFX91835.1 - 1.3e-59 202.0 1.6 1.6e-59 201.6 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91835.1 - 1.9e-05 24.7 7.7 4.1e-05 23.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 KFX91836.1 - 4.4e-103 345.4 36.1 5.3e-103 345.2 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX91836.1 - 1.1e-20 73.9 37.4 1.6e-20 73.4 37.4 1.3 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 KFX91836.1 - 6.9 5.3 16.4 1.5 7.5 0.8 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PEX11 PF05648.14 KFX91837.1 - 1.7e-29 102.9 0.0 2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M20 PF01546.28 KFX91838.1 - 1.4e-28 100.0 0.0 2.1e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX91838.1 - 1.4e-10 41.1 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFX91838.1 - 0.0065 16.2 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M24 PF00557.24 KFX91839.1 - 3.7e-21 75.8 0.1 5e-21 75.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KFX91839.1 - 2.6e-17 63.7 0.0 4.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Beta_elim_lyase PF01212.21 KFX91840.1 - 4.5e-79 265.8 0.0 6.3e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFX91840.1 - 0.001 17.7 0.0 0.0015 17.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX91840.1 - 0.0016 17.7 0.0 0.0057 15.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFX91840.1 - 0.018 14.4 0.1 0.11 11.7 0.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PIN_12 PF16289.5 KFX91840.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 PIN domain Aldedh PF00171.22 KFX91841.1 - 1.2e-184 614.1 0.3 1.4e-184 613.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_32C PF08244.12 KFX91842.1 - 2.1e-22 79.8 0.6 3e-22 79.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KFX91842.1 - 2e-18 67.0 0.0 3.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_11 PF08241.12 KFX91843.1 - 2.4e-09 37.7 0.0 4.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX91843.1 - 1.7e-06 28.6 0.0 4.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain HpcH_HpaI PF03328.14 KFX91844.1 - 4.6e-24 84.8 0.0 6.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2-oxoacid_dh PF00198.23 KFX91844.1 - 0.036 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SET PF00856.28 KFX91852.1 - 5.2e-08 33.5 0.0 4.6e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 SET domain MmgE_PrpD PF03972.14 KFX91854.1 - 3.5e-148 493.8 0.0 4.4e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Toxin_23 PF08093.11 KFX91856.1 - 3.8 7.7 10.6 0.24 11.6 5.1 1.9 2 0 0 2 2 2 0 Magi 5 toxic peptide family FA_hydroxylase PF04116.13 KFX91861.1 - 8.5e-18 65.0 1.4 8.5e-18 65.0 1.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Stn1 PF10451.9 KFX91861.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Retrotrans_gag PF03732.17 KFX91862.1 - 8.9e-06 25.9 0.1 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein DUF1759 PF03564.15 KFX91862.1 - 0.00096 19.1 0.1 0.0013 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Cry1Ac_D5 PF17997.1 KFX91862.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Fibrillin_U_N PF18193.1 KFX91862.1 - 0.4 10.8 5.0 0.13 12.3 0.9 2.3 3 0 0 3 3 3 0 Fibrillin 1 unique N-terminal domain Haem_degrading PF03928.14 KFX91863.1 - 2.3e-31 108.3 0.1 2.6e-31 108.1 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Diacid_rec PF05651.13 KFX91863.1 - 0.055 13.1 0.2 0.055 13.1 0.2 1.6 2 0 0 2 2 2 0 Putative sugar diacid recognition ADH_N PF08240.12 KFX91864.1 - 1.8e-27 95.4 0.7 3.7e-27 94.4 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX91864.1 - 2.2e-09 37.3 0.0 0.0001 22.3 0.0 3.1 2 1 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFX91864.1 - 0.011 15.7 0.6 0.042 13.8 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated FANCL_C PF11793.8 KFX91864.1 - 0.035 14.3 0.5 0.077 13.2 0.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain UDPGT PF00201.18 KFX91865.1 - 3.6e-08 32.7 0.0 4.8e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase adh_short_C2 PF13561.6 KFX91870.1 - 8e-56 189.2 0.7 8e-56 189.2 0.7 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX91870.1 - 2.7e-44 151.0 4.6 3.9e-41 140.7 0.5 3.2 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 KFX91870.1 - 1e-13 51.3 0.0 1.3e-12 47.7 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX91870.1 - 5.5e-10 39.4 2.8 1.5e-08 34.8 0.5 2.7 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 KFX91870.1 - 2.6e-09 36.5 0.0 4.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SUR7 PF06687.12 KFX91870.1 - 1.5e-07 31.2 0.5 2.6e-07 30.5 0.5 1.3 1 0 0 1 1 1 1 SUR7/PalI family NAD_binding_4 PF07993.12 KFX91870.1 - 2e-05 23.9 0.5 0.029 13.5 0.2 3.1 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFX91870.1 - 2.5e-05 24.3 0.1 6.3e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX91870.1 - 0.0011 18.2 0.6 0.0038 16.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX91870.1 - 0.0078 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFX91870.1 - 0.062 12.9 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 NmrA-like family DUF1067 PF06362.11 KFX91871.1 - 0.021 15.6 0.1 0.028 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) Epimerase PF01370.21 KFX91872.1 - 1.3e-07 31.4 0.0 3.4e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX91872.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans_2 PF11951.8 KFX91873.1 - 2.7e-13 49.5 0.3 3.8e-13 49.0 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 KFX91879.1 - 2e-80 270.7 0.0 2.5e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX91879.1 - 0.00031 19.8 0.1 0.0032 16.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFX91879.1 - 0.00096 17.8 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ELFV_dehydrog_N PF02812.18 KFX91879.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DegT_DnrJ_EryC1 PF01041.17 KFX91879.1 - 0.47 9.7 2.8 0.63 9.3 1.1 1.9 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Choline_transpo PF04515.12 KFX91881.1 - 3.6e-80 269.6 32.8 3.6e-80 269.6 32.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KFX91881.1 - 0.027 15.2 8.0 0.06 14.0 8.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KFX91881.1 - 0.055 13.1 16.8 0.081 12.5 16.8 1.2 1 0 0 1 1 1 0 Spt20 family Deltameth_res PF16020.5 KFX91881.1 - 7.7 6.5 8.3 24 4.9 0.0 4.1 3 0 0 3 3 3 0 Deltamethrin resistance Cellulase PF00150.18 KFX91882.1 - 2.6e-17 63.2 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SWIRM PF04433.17 KFX91888.1 - 1.3e-13 51.0 0.0 9e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Sugar_tr PF00083.24 KFX91890.1 - 1.9e-118 396.2 21.2 3.4e-118 395.4 21.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91890.1 - 4.1e-29 101.6 49.9 3.8e-24 85.3 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily peroxidase PF00141.23 KFX91891.1 - 5.9e-85 284.6 0.0 9.3e-49 166.2 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Herpes_U59 PF04529.12 KFX91891.1 - 0.12 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus U59 protein CN_hydrolase PF00795.22 KFX91892.1 - 1.3e-36 126.3 0.0 2.4e-36 125.4 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase CFEM PF05730.11 KFX91894.1 - 4.7e-08 33.0 9.8 4.7e-08 33.0 9.8 2.0 2 0 0 2 2 2 1 CFEM domain Zn_clus PF00172.18 KFX91894.1 - 0.0004 20.4 11.2 0.0008 19.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX91895.1 - 1e-41 143.0 58.3 9.5e-41 139.9 57.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX91895.1 - 1.9e-12 46.5 20.7 2.8e-12 45.8 20.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX91895.1 - 0.00066 18.1 2.6 0.00066 18.1 2.6 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Meckelin PF09773.9 KFX91895.1 - 1.5 6.8 3.0 2.2 6.2 3.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Pkinase PF00069.25 KFX91897.1 - 1.8e-26 93.1 0.0 1.4e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91897.1 - 2.2e-10 40.3 0.0 0.0003 20.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KFX91897.1 - 0.00078 19.1 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFX91897.1 - 0.025 13.4 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sod_Cu PF00080.20 KFX91898.1 - 3.3e-46 157.0 5.4 3.7e-46 156.8 5.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Tox-HNH-EHHH PF15657.6 KFX91898.1 - 0.41 11.1 4.4 0.091 13.1 1.1 1.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins VGCC_beta4Aa_N PF12052.8 KFX91899.1 - 1.4 9.1 4.1 0.54 10.4 0.5 1.9 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF4405 PF14358.6 KFX91908.1 - 0.028 14.9 0.2 0.037 14.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) NAD_binding_10 PF13460.6 KFX91928.1 - 1.7e-13 50.9 0.3 2.1e-13 50.6 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KFX91928.1 - 0.029 14.5 0.0 0.049 13.7 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 KFX91928.1 - 0.033 13.7 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX91928.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 KFX91928.1 - 0.068 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4395 PF14340.6 KFX91935.1 - 0.051 13.9 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Abhydrolase_6 PF12697.7 KFX91941.1 - 1.8e-11 45.1 0.0 2.9e-11 44.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX91941.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KFX91941.1 - 0.00056 19.8 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 KFX91941.1 - 0.0016 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFX91941.1 - 0.019 14.0 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PRP4 PF08799.11 KFX91942.1 - 4.1e-13 48.6 0.7 1e-12 47.4 0.7 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Med13_C PF06333.12 KFX91944.1 - 1.1e-85 287.8 2.9 3.5e-85 286.2 2.9 1.9 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KFX91944.1 - 6e-20 71.9 4.2 1.3e-19 70.7 4.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KFX91944.1 - 2.1e-13 50.6 2.3 8.2e-06 25.8 0.1 3.2 2 1 1 3 3 3 2 MID domain of medPIWI Collagen PF01391.18 KFX91944.1 - 0.093 12.5 2.8 0.31 10.8 2.8 1.9 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) PNP_UDP_1 PF01048.20 KFX91945.1 - 3e-41 141.2 0.3 3.5e-41 141.0 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-RING_4 PF14570.6 KFX91946.1 - 7.6e-20 70.4 12.1 1.3e-19 69.7 12.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFX91946.1 - 8.4e-08 32.0 6.9 1.7e-07 31.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFX91946.1 - 6.9e-07 29.0 0.0 3.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 KFX91946.1 - 0.00014 21.4 2.5 0.00014 21.4 2.5 3.3 3 1 0 3 3 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KFX91946.1 - 0.00041 20.6 9.8 0.00076 19.8 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFX91946.1 - 0.0039 17.0 8.7 0.11 12.4 9.4 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KFX91946.1 - 0.029 14.3 4.2 0.056 13.4 4.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.6 KFX91946.1 - 0.044 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KFX91946.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated FYVE PF01363.21 KFX91946.1 - 0.12 12.5 3.7 0.25 11.5 3.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KFX91946.1 - 0.14 12.1 9.9 0.27 11.2 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX91946.1 - 0.29 11.1 10.2 0.5 10.4 10.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.6 KFX91946.1 - 0.34 11.1 4.3 0.83 9.8 4.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KFX91946.1 - 1.8 8.4 9.9 3.2 7.7 9.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4288 PF14119.6 KFX91946.1 - 5.6 7.4 5.5 4.7 7.7 2.7 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4288) Complex1_30kDa PF00329.19 KFX91947.1 - 5e-47 159.5 0.0 7e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1256 PF06866.11 KFX91948.1 - 0.043 13.2 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) UPF0242 PF06785.11 KFX91953.1 - 0.0033 17.6 12.4 0.0033 17.6 12.4 5.9 2 2 3 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus Sec8_exocyst PF04048.14 KFX91953.1 - 1.2 9.0 31.3 0.083 12.8 1.8 6.1 4 3 1 6 6 6 0 Sec8 exocyst complex component specific domain MLTR_LBD PF17765.1 KFX91953.1 - 5.3 7.1 6.2 1.1 9.4 0.9 2.3 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain PKcGMP_CC PF16808.5 KFX91953.1 - 8.5 6.3 15.0 0.24 11.3 0.2 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EVC2_like PF12297.8 KFX91954.1 - 0.066 11.9 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein PDR_assoc PF08370.11 KFX91954.1 - 2.9 7.7 3.8 18 5.2 0.5 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated NUC153 PF08159.12 KFX91955.1 - 2e-12 46.7 1.3 3.8e-12 45.8 1.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFX91955.1 - 5.1e-07 30.3 0.2 0.019 15.8 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91955.1 - 0.047 14.0 0.0 0.2 12.0 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Sugar_tr PF00083.24 KFX91957.1 - 3.3e-69 233.9 11.3 4e-69 233.6 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91957.1 - 1.5e-22 80.0 20.5 2.9e-22 79.1 20.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX91957.1 - 0.00035 19.1 2.9 0.00049 18.7 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX91957.1 - 0.059 11.7 4.0 0.59 8.4 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 KFX91957.1 - 0.079 13.2 2.9 0.28 11.5 2.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) FAD_binding_3 PF01494.19 KFX91958.1 - 2e-27 96.3 0.0 3.5e-27 95.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX91958.1 - 9.8e-11 41.8 3.2 1.1e-06 28.5 1.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91958.1 - 2.8e-08 33.3 1.1 0.0013 18.1 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX91958.1 - 1.9e-07 31.2 0.3 4.8e-07 29.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX91958.1 - 4e-06 26.9 0.8 0.075 13.0 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX91958.1 - 2.8e-05 23.0 0.3 0.0023 16.7 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KFX91958.1 - 3e-05 23.3 1.6 0.00045 19.4 1.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KFX91958.1 - 3.4e-05 23.3 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KFX91958.1 - 7.1e-05 22.1 1.0 0.00013 21.2 0.4 1.8 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX91958.1 - 7.9e-05 22.0 0.3 0.057 12.7 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX91958.1 - 0.00092 18.5 0.2 0.0021 17.4 0.1 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KFX91958.1 - 0.0022 17.2 0.5 0.0079 15.3 0.5 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFX91958.1 - 0.0022 16.9 0.4 0.74 8.6 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KFX91958.1 - 0.003 18.1 0.2 2 9.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX91958.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KFX91958.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_43 PF04616.14 KFX91959.1 - 5.9e-38 130.8 4.2 8.5e-38 130.3 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX91959.1 - 2.4e-25 89.5 0.1 3.9e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain LPMO_10 PF03067.15 KFX91960.1 - 0.11 13.2 0.6 0.23 12.1 0.1 1.8 2 0 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading BACON PF13004.7 KFX91960.1 - 7.6 6.6 13.0 0.59 10.2 1.7 3.2 3 0 0 3 3 3 0 Putative binding domain, N-terminal NmrA PF05368.13 KFX91962.1 - 1.6e-23 83.5 0.0 2e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX91962.1 - 6.7e-15 55.5 0.4 5.8e-14 52.4 0.4 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX91962.1 - 0.00051 19.6 0.7 0.0012 18.3 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 KFX91962.1 - 0.038 14.4 0.1 0.093 13.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DapB_N PF01113.20 KFX91962.1 - 0.071 13.2 0.5 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFX91962.1 - 0.086 13.3 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF5612 PF18462.1 KFX91962.1 - 0.091 12.6 1.1 1.4 8.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) RmlD_sub_bind PF04321.17 KFX91962.1 - 0.095 11.8 0.3 1.8 7.6 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KFX91962.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 KFX91963.1 - 8.5e-14 51.2 0.3 1.5e-13 50.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91963.1 - 1.2e-07 31.7 9.6 2e-07 31.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 KFX91964.1 - 2.6e-20 73.2 0.4 4.2e-19 69.2 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX91964.1 - 1e-08 36.0 0.0 1.4e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX91964.1 - 0.0026 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SKG6 PF08693.10 KFX91965.1 - 4.1e-07 29.3 0.1 8.7e-07 28.2 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 KFX91965.1 - 0.01 15.7 0.8 0.018 14.9 0.1 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 Scm3 PF10384.9 KFX91966.1 - 2.7e-20 71.8 0.1 2.7e-20 71.8 0.1 2.5 2 1 0 2 2 2 1 Centromere protein Scm3 Clr5 PF14420.6 KFX91966.1 - 2.8e-09 37.1 0.1 4.9e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain Myb_DNA-bind_2 PF08914.11 KFX91966.1 - 0.0029 17.8 2.2 0.0061 16.7 1.6 1.9 2 0 0 2 2 2 1 Rap1 Myb domain LCAT PF02450.15 KFX91969.1 - 1.6e-104 350.2 0.0 2e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFX91969.1 - 0.00049 20.8 0.0 0.00098 19.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 KFX91969.1 - 0.18 11.3 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.25 KFX91970.1 - 4.3e-17 62.4 0.0 5.1e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX91970.1 - 5.8e-10 39.2 0.0 7.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX91970.1 - 1.3e-09 38.4 0.0 2e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX91970.1 - 4.7e-09 36.1 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFX91970.1 - 1.1e-06 29.4 0.0 1.2e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFX91970.1 - 9.3e-06 25.4 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX91970.1 - 0.00017 21.6 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX91970.1 - 0.0026 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KFX91970.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF1917 PF08939.10 KFX91971.1 - 4.9e-69 233.2 0.0 5.8e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.32 KFX91972.1 - 0.00037 21.2 1.1 2 9.4 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Fungal_trans_2 PF11951.8 KFX91973.1 - 1.8e-15 56.7 0.3 8.4e-15 54.5 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91973.1 - 8.4e-07 29.0 12.5 1.4e-06 28.3 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM70 PF14967.6 KFX91973.1 - 0.99 8.8 10.4 0.65 9.4 3.3 2.2 2 0 0 2 2 2 0 FAM70 protein RAMP4 PF06624.12 KFX91974.1 - 0.063 13.4 1.6 5.1 7.2 0.3 2.2 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 TMEMspv1-c74-12 PF11044.8 KFX91974.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sec23_trunk PF04811.15 KFX91975.1 - 4.4e-70 236.0 0.0 6.3e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFX91975.1 - 7.1e-23 80.4 0.0 2.6e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFX91975.1 - 4.9e-18 65.7 0.0 9.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFX91975.1 - 1.8e-16 59.9 4.4 3.2e-16 59.1 4.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFX91975.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFX91975.1 - 0.041 13.3 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sporozoite_P67 PF05642.11 KFX91975.1 - 2.2 6.3 6.7 3.8 5.5 6.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG6 PF06419.11 KFX91976.1 - 6e-225 748.2 12.6 6.9e-225 748.0 12.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KFX91976.1 - 0.005 16.9 1.5 0.033 14.3 0.3 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dad4 PF08650.10 KFX91976.1 - 0.081 12.9 0.2 14 5.7 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad4 Abi_C PF14355.6 KFX91976.1 - 0.082 13.0 0.4 0.53 10.4 0.1 2.5 3 0 0 3 3 3 0 Abortive infection C-terminus AAA PF00004.29 KFX91977.1 - 6.8e-38 130.1 0.0 4e-37 127.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFX91977.1 - 4e-08 33.1 0.0 1.2e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFX91977.1 - 1.5e-07 31.1 0.0 4.2e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFX91977.1 - 8.2e-07 28.9 0.0 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFX91977.1 - 4.2e-06 27.1 0.4 0.0005 20.3 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX91977.1 - 0.0004 20.8 1.6 0.0021 18.5 0.5 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KFX91977.1 - 0.00089 18.6 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFX91977.1 - 0.0019 18.2 0.0 0.0089 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KFX91977.1 - 0.0027 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KFX91977.1 - 0.0035 17.1 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFX91977.1 - 0.0056 16.1 0.8 0.01 15.2 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFX91977.1 - 0.0094 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFX91977.1 - 0.01 16.0 0.1 0.079 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFX91977.1 - 0.019 15.0 0.0 0.057 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX91977.1 - 0.029 14.6 1.9 0.78 10.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KFX91977.1 - 0.056 13.0 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFX91977.1 - 0.078 13.5 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFX91977.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX91977.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KFX91977.1 - 0.17 11.4 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_S17 PF00366.20 KFX91978.1 - 1.3e-20 73.3 0.9 1.3e-20 73.3 0.9 1.4 2 0 0 2 2 2 1 Ribosomal protein S17 WSN PF02206.18 KFX91978.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function GRIM-19 PF06212.12 KFX91979.1 - 9.3e-21 74.2 0.0 2.1e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KFX91980.1 - 7.2e-29 100.9 0.0 1.6e-21 77.0 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF1230 PF06799.11 KFX91981.1 - 0.012 15.7 1.1 0.015 15.4 1.1 1.1 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 FixQ PF05545.11 KFX91981.1 - 2.5 8.1 5.4 2.7 8.0 1.9 2.1 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Acetyltransf_1 PF00583.25 KFX91982.1 - 6.9e-07 29.5 0.1 1.2e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX91982.1 - 2.3e-05 24.7 0.1 5e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX91982.1 - 7.6e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX91982.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3472 PF11958.8 KFX91983.1 - 0.0036 17.8 0.2 0.0053 17.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Melibiase_2 PF16499.5 KFX91984.1 - 1.5e-56 191.7 1.1 2.4e-56 191.0 1.1 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFX91984.1 - 1.9e-12 47.1 0.4 1.9e-12 47.1 0.4 2.6 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 KFX91984.1 - 4.1e-09 36.8 3.0 7.3e-09 35.9 3.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.18 KFX91984.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Melibiase RicinB_lectin_2 PF14200.6 KFX91984.1 - 1.1 10.0 6.6 1.2 9.9 2.2 2.9 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Fig1 PF12351.8 KFX91986.1 - 4.3e-56 189.8 5.4 4.3e-56 189.8 5.4 2.1 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KFX91986.1 - 5.7e-08 32.6 11.6 8.2e-08 32.1 11.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KFX91986.1 - 0.11 11.5 14.1 0.31 10.0 13.7 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4969 PF16339.5 KFX91986.1 - 0.3 11.5 2.8 11 6.5 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) HSF_DNA-bind PF00447.17 KFX91987.1 - 8.8e-32 109.6 2.8 1.9e-31 108.5 2.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KFX91987.1 - 1.2e-20 73.8 0.0 2.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 KFX91987.1 - 0.084 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Ets-domain Gp58 PF07902.11 KFX91987.1 - 0.28 9.4 0.7 0.42 8.8 0.7 1.1 1 0 0 1 1 1 0 gp58-like protein Nucleo_P87 PF07267.11 KFX91987.1 - 7.9 5.2 13.1 1.6 7.5 9.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Pkinase PF00069.25 KFX91992.1 - 1.9e-67 227.4 0.0 2.7e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91992.1 - 1.9e-31 109.3 0.0 2.7e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX91992.1 - 0.00061 19.2 0.3 0.001 18.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFX91992.1 - 0.0037 16.3 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX91992.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFX91992.1 - 0.04 13.8 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFX91992.1 - 0.084 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Homeobox_KN PF05920.11 KFX92004.1 - 9.5e-14 51.0 0.2 2.4e-13 49.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFX92004.1 - 2e-06 27.6 0.5 5.6e-06 26.1 0.5 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KFX92004.1 - 0.019 15.7 21.0 0.023 15.5 2.4 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX92004.1 - 0.055 13.9 20.4 2.4 8.8 0.8 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 KFX92004.1 - 1.1 9.8 8.8 20 5.8 1.0 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4124 PF13511.6 KFX92004.1 - 2.6 8.4 4.7 5.4 7.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) GTP_EFTU PF00009.27 KFX92006.1 - 6.4e-41 140.0 0.0 1.1e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFX92006.1 - 2e-26 91.9 0.1 5.8e-26 90.4 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KFX92006.1 - 4.4e-17 61.9 0.1 5e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX92006.1 - 1.4e-10 41.4 0.0 5.1e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFX92006.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KFX92006.1 - 0.0082 15.9 0.0 0.098 12.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV PX PF00787.24 KFX92007.1 - 6.3e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFX92007.1 - 1.7e-09 37.6 0.6 2.8e-09 36.9 0.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like CCT_2 PF09425.10 KFX92007.1 - 0.3 11.0 4.6 9.9 6.2 0.1 2.9 2 0 0 2 2 2 0 Divergent CCT motif SAP PF02037.27 KFX92008.1 - 6.7e-13 48.1 0.2 1.5e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 SAP domain Pribosyltran_N PF13793.6 KFX92009.1 - 5.6e-42 142.4 0.1 5.2e-40 136.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFX92009.1 - 3.3e-33 115.3 0.0 3.6e-28 98.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFX92009.1 - 1.6e-07 31.0 0.0 8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 KFX92010.1 - 2.1e-58 197.7 0.0 3.3e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing OmdA PF13376.6 KFX92010.1 - 0.0093 16.0 0.7 0.35 10.9 0.1 2.9 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated XPG_I PF00867.18 KFX92010.1 - 0.11 12.9 0.2 0.35 11.2 0.0 1.9 2 0 0 2 2 2 0 XPG I-region DUF383 PF04063.14 KFX92012.1 - 5.5e-68 228.4 0.1 1.5e-67 227.0 0.0 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KFX92012.1 - 2.4e-21 75.3 1.7 6e-21 74.0 1.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Mic1 PF07035.12 KFX92012.1 - 0.022 14.5 0.2 0.052 13.3 0.2 1.7 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like DUF4401 PF14351.6 KFX92013.1 - 0.0078 15.6 6.3 0.16 11.3 7.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4401) Ycf66_N PF07444.11 KFX92013.1 - 0.22 11.6 0.1 0.22 11.6 0.1 2.2 2 1 1 3 3 3 0 Ycf66 protein N-terminus DUF998 PF06197.13 KFX92013.1 - 0.28 10.8 12.8 0.1 12.2 6.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF998) PLAC8 PF04749.17 KFX92014.1 - 1.4e-15 58.1 12.7 1.9e-15 57.7 12.7 1.2 1 0 0 1 1 1 1 PLAC8 family Amidohydro_1 PF01979.20 KFX92020.1 - 6e-50 170.5 0.0 7.1e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX92020.1 - 6e-10 39.2 0.0 8.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family YopE_N PF09020.10 KFX92022.1 - 0.022 15.0 1.9 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 YopE, N terminal Peptidase_M28 PF04389.17 KFX92023.1 - 3.4e-32 111.7 0.0 4.6e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Kelch_5 PF13854.6 KFX92024.1 - 0.002 18.1 0.8 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 Kelch motif SKG6 PF08693.10 KFX92024.1 - 0.011 15.1 2.1 0.019 14.4 1.1 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Kelch_2 PF07646.15 KFX92024.1 - 0.17 11.9 3.3 3.4 7.8 0.1 3.4 3 0 0 3 3 3 0 Kelch motif DUF4677 PF15726.5 KFX92024.1 - 0.25 11.5 1.5 0.33 11.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) Kelch_3 PF13415.6 KFX92024.1 - 0.3 11.4 14.3 0.68 10.3 0.3 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain AA_permease PF00324.21 KFX92025.1 - 2.4e-126 422.2 37.5 2.7e-126 422.0 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX92025.1 - 9e-29 100.5 45.0 1.1e-28 100.2 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease zf-His_Me_endon PF05551.11 KFX92026.1 - 0.00044 20.4 0.5 0.0015 18.8 0.5 1.8 1 1 0 1 1 1 1 Zinc-binding loop region of homing endonuclease EXOSC1 PF10447.9 KFX92030.1 - 9.2e-14 52.0 0.2 1.3e-13 51.5 0.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Annexin PF00191.20 KFX92034.1 - 8.6e-73 240.4 4.6 5.6e-19 68.0 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 KFX92034.1 - 0.011 16.2 1.4 2.8 8.4 0.0 3.7 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF5638 PF18688.1 KFX92034.1 - 0.021 15.1 0.0 2.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5638) HAP1_N PF04849.13 KFX92038.1 - 0.0036 16.6 1.7 0.0045 16.3 1.7 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DivIC PF04977.15 KFX92038.1 - 0.0043 16.8 0.7 2.1 8.2 0.1 2.2 2 0 0 2 2 2 2 Septum formation initiator FlaC_arch PF05377.11 KFX92038.1 - 0.03 14.7 3.4 0.72 10.3 0.9 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 KFX92038.1 - 0.035 14.1 3.7 0.07 13.2 3.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 KFX92038.1 - 0.036 14.6 2.5 0.75 10.4 0.1 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Occludin_ELL PF07303.13 KFX92038.1 - 0.046 14.4 3.0 4.4 8.1 0.2 2.3 1 1 0 2 2 2 0 Occludin homology domain LPP PF04728.13 KFX92038.1 - 0.052 13.9 3.8 6.7 7.2 1.5 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PI_PP_I PF18363.1 KFX92038.1 - 0.057 13.6 0.4 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF4140 PF13600.6 KFX92038.1 - 0.061 13.8 0.1 0.19 12.2 0.1 1.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dad2 PF08654.10 KFX92038.1 - 0.097 13.1 2.3 0.69 10.4 0.3 2.2 1 1 0 2 2 2 0 DASH complex subunit Dad2 DUF1664 PF07889.12 KFX92038.1 - 0.11 12.6 4.0 1.4 9.0 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KFX92038.1 - 0.19 12.2 4.1 9.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF2802 PF10975.8 KFX92038.1 - 0.2 11.8 4.8 2 8.6 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Laminin_II PF06009.12 KFX92038.1 - 0.27 11.2 4.2 3.3 7.7 0.3 2.1 1 1 1 2 2 2 0 Laminin Domain II YabA PF06156.13 KFX92038.1 - 0.29 11.8 4.2 2.8 8.6 0.6 2.2 1 1 0 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 KFX92038.1 - 0.29 11.3 5.5 3.1 8.0 0.3 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2205 PF10224.9 KFX92038.1 - 2 8.5 6.2 7.6 6.6 0.4 2.3 1 1 0 2 2 2 0 Short coiled-coil protein Rx_N PF18052.1 KFX92041.1 - 0.025 14.8 0.3 0.091 13.0 0.4 1.9 2 0 0 2 2 2 0 Rx N-terminal domain DMPK_coil PF08826.10 KFX92041.1 - 0.067 13.3 0.6 0.16 12.1 0.6 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like adh_short PF00106.25 KFX92053.1 - 2e-06 27.4 2.2 2.9e-06 26.9 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX92053.1 - 0.00017 21.2 1.4 0.00023 20.8 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX92053.1 - 0.0078 16.1 5.8 0.25 11.2 5.8 2.2 1 1 0 1 1 1 1 KR domain Tim54 PF11711.8 KFX92059.1 - 4.6e-88 295.5 0.0 5.3e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 KFX92060.1 - 8.6e-59 199.0 0.0 1.1e-57 195.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92060.1 - 1.7e-26 93.1 0.0 1.1e-20 74.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX92060.1 - 3e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFX92060.1 - 0.00049 20.1 3.4 0.0086 16.0 0.2 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX92060.1 - 0.00063 19.2 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX92060.1 - 0.00082 18.8 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFX92060.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SF3A2 PF16835.5 KFX92061.1 - 3e-37 126.9 0.1 4.4e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFX92061.1 - 1.1e-05 25.6 0.5 2.1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KFX92061.1 - 0.061 12.9 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.25 KFX92062.1 - 1.2e-17 63.7 0.3 2.4e-17 62.7 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 KFX92062.1 - 3.6e-06 26.6 0.9 0.058 12.9 0.1 3.5 3 0 0 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 KFX92062.1 - 8.1e-06 26.1 12.9 0.21 12.1 0.4 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX92062.1 - 0.00011 21.8 9.1 0.27 11.0 0.7 4.5 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFX92062.1 - 0.00072 19.4 9.5 6.1 7.2 0.1 6.2 7 0 0 7 7 7 1 Leucine Rich repeat Torus PF16131.5 KFX92062.1 - 0.017 15.8 0.0 0.06 14.0 0.0 2.0 1 0 0 1 1 1 0 Torus domain zf-CCCH PF00642.24 KFX92062.1 - 0.056 13.4 3.7 0.1 12.6 3.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_lig_T4_1 PF09511.10 KFX92063.1 - 1.2e-85 286.9 0.0 2.1e-85 286.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 KFX92063.1 - 2.5e-84 282.7 0.1 3.5e-84 282.2 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 KFX92063.1 - 3.1e-57 193.3 0.3 5.6e-57 192.5 0.3 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain RNA_ligase PF09414.10 KFX92063.1 - 0.017 15.5 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA ligase AAA_18 PF13238.6 KFX92063.1 - 0.066 13.8 0.1 0.47 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ank_5 PF13857.6 KFX92064.1 - 1.6e-11 44.2 0.3 6.5e-09 35.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX92064.1 - 1.1e-09 38.7 0.1 3e-07 30.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX92064.1 - 1.4e-08 35.1 0.0 4.7e-06 27.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92064.1 - 1.6e-05 24.9 0.5 0.00088 19.6 0.1 3.3 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 KFX92064.1 - 0.037 14.5 0.1 0.47 11.0 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat YusW PF14039.6 KFX92064.1 - 0.04 14.4 0.4 1.8 9.1 0.1 2.5 3 0 0 3 3 3 0 YusW-like protein Ribonuc_P_40 PF08584.11 KFX92065.1 - 7.7e-59 199.3 0.0 1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Zn_clus PF00172.18 KFX92085.1 - 9.7e-06 25.6 9.2 2.1e-05 24.6 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX92085.1 - 0.075 12.0 0.1 0.18 10.8 0.1 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2039 PF10217.9 KFX92085.1 - 0.45 10.9 5.3 0.79 10.1 3.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Mito_carr PF00153.27 KFX92086.1 - 3.3e-37 126.3 2.2 1.5e-13 50.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E3_UFM1_ligase PF09743.9 KFX92086.1 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Ank_2 PF12796.7 KFX92087.1 - 7.4e-51 170.7 5.1 6.9e-15 55.4 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX92087.1 - 3.1e-35 120.1 0.8 1.1e-08 35.4 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92087.1 - 8.3e-34 111.8 2.4 0.0019 18.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KFX92087.1 - 5.4e-28 96.2 17.1 0.0013 19.1 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFX92087.1 - 4.8e-22 77.7 13.2 0.00031 21.0 0.2 7.8 1 1 8 9 9 9 7 Ankyrin repeats (many copies) DUF2384 PF09722.10 KFX92087.1 - 0.0011 18.9 0.2 1.8 8.7 0.0 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF2384) FA PF08736.11 KFX92087.1 - 0.055 13.6 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 3 0 FERM adjacent (FA) polyprenyl_synt PF00348.17 KFX92088.1 - 3.9e-45 153.9 0.0 5.7e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KFX92088.1 - 0.072 12.4 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Dsl1_C PF11989.8 KFX92089.1 - 0.00036 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 KFX92089.1 - 0.0065 15.1 0.1 0.043 12.4 0.3 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 DUF3701 PF12482.8 KFX92089.1 - 0.082 13.0 0.0 0.34 11.0 0.0 2.1 1 0 0 1 1 1 0 Phage integrase protein LRR_4 PF12799.7 KFX92090.1 - 1.9e-05 24.9 5.2 0.2 12.1 0.1 5.8 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFX92090.1 - 0.077 12.5 0.1 5.2 6.5 0.1 2.5 1 1 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KFX92090.1 - 0.27 11.4 5.6 21 5.5 0.0 5.2 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 KFX92090.1 - 0.41 10.4 6.9 0.2 11.5 0.3 3.6 5 0 0 5 5 5 0 Leucine rich repeat SNF2_N PF00176.23 KFX92091.1 - 5e-47 160.3 0.0 1.1e-45 155.9 0.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX92091.1 - 3.1e-16 59.7 0.0 8.1e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KFX92091.1 - 1.2e-05 25.1 10.9 1.2e-05 25.1 10.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFX92091.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KFX92091.1 - 0.0069 16.7 14.4 0.0069 16.7 14.4 3.1 3 0 0 3 3 3 1 Ring finger domain AAA_34 PF13872.6 KFX92091.1 - 0.0085 15.0 0.0 0.036 13.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 KFX92091.1 - 0.054 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase EVE PF01878.18 KFX92093.1 - 5.5e-31 107.5 0.0 6.3e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 EVE domain FmrO PF07091.11 KFX92097.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Babuvirus_MP PF07234.11 KFX92097.1 - 0.029 14.5 0.1 0.033 14.4 0.1 1.1 1 0 0 1 1 1 0 Movement and RNA silencing protein DUF5305 PF17231.2 KFX92097.1 - 0.06 12.7 0.0 0.072 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) WBP-1 PF11669.8 KFX92097.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3506 PF12014.8 KFX92098.1 - 3.4e-57 192.3 0.1 3.1e-56 189.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KFX92098.1 - 0.0002 21.2 0.3 0.00036 20.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX92098.1 - 0.00045 20.0 0.6 0.00084 19.1 0.6 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFX92098.1 - 0.021 15.4 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1769 PF08588.10 KFX92099.1 - 4.9e-25 87.5 0.3 9.4e-25 86.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF4568 PF15132.6 KFX92099.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) ADH_zinc_N PF00107.26 KFX92100.1 - 2.7e-32 111.5 1.0 5.1e-32 110.6 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX92100.1 - 4.8e-13 50.3 0.0 8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX92100.1 - 0.00013 21.8 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KFX92100.1 - 0.0027 18.0 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain YAcAr PF10686.9 KFX92100.1 - 0.0097 15.8 0.2 0.42 10.6 0.0 2.4 2 0 0 2 2 2 1 YspA, cpYpsA-related SLOG family adh_short PF00106.25 KFX92100.1 - 0.074 12.5 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Spt5-NGN PF03439.13 KFX92101.1 - 7.2e-25 86.7 0.1 1.3e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFX92101.1 - 4.6e-20 72.4 8.8 4.6e-20 72.4 8.8 3.8 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KFX92101.1 - 3.7e-17 62.6 28.8 2.5e-16 60.0 14.1 4.9 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KFX92101.1 - 9.9e-10 38.0 12.6 0.00083 19.2 0.1 5.5 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KFX92101.1 - 0.00014 22.0 0.9 0.0009 19.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 KFX92101.1 - 0.8 9.9 2.9 1.8 8.7 2.9 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family FSH1 PF03959.13 KFX92102.1 - 0.02 14.5 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Copper-fist PF00649.18 KFX92110.1 - 1.7e-11 43.4 0.5 4.2e-11 42.2 0.5 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Abhydrolase_3 PF07859.13 KFX92111.1 - 1.4e-40 139.5 0.0 1.7e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX92111.1 - 2.3e-08 33.4 0.5 6.2e-08 32.0 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KFX92111.1 - 0.0009 18.9 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 KFX92111.1 - 0.018 14.5 0.2 0.38 10.2 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFX92111.1 - 0.073 12.0 0.0 0.12 11.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KFX92111.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.6 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase E1-E2_ATPase PF00122.20 KFX92112.1 - 5.5e-49 166.1 0.1 1.5e-48 164.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KFX92112.1 - 2.3e-37 127.3 0.2 2.7e-12 47.0 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KFX92112.1 - 6e-36 124.7 0.2 1.5e-35 123.4 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX92112.1 - 1.2e-05 25.8 0.0 0.00053 20.4 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX92112.1 - 2e-05 24.5 0.1 0.001 18.9 0.1 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PSRP-3_Ycf65 PF04839.13 KFX92112.1 - 0.17 12.1 0.0 35 4.7 0.0 2.5 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) DUF4342 PF14242.6 KFX92112.1 - 0.36 10.9 2.5 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) Caveolin PF01146.17 KFX92112.1 - 1.4 8.9 6.3 1.7 8.6 1.4 2.6 2 0 0 2 2 2 0 Caveolin DJ-1_PfpI PF01965.24 KFX92119.1 - 1.8e-07 31.1 0.1 2.1e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Pkinase PF00069.25 KFX92120.1 - 1.9e-18 66.8 0.0 3.8e-17 62.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92120.1 - 4.2e-08 32.8 0.1 1.5e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FMO-like PF00743.19 KFX92121.1 - 3.1e-12 45.7 0.1 1.2e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX92121.1 - 1.6e-11 44.0 0.0 1.7e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX92121.1 - 5.3e-09 35.7 0.0 5.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX92121.1 - 4.6e-08 32.6 0.0 2.6e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX92121.1 - 0.00014 22.0 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX92121.1 - 0.004 17.2 0.5 16 5.5 0.1 4.4 4 1 1 5 5 5 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFX92121.1 - 0.013 16.0 0.1 1 9.9 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFX92121.1 - 0.11 12.7 2.9 38 4.6 0.2 4.4 5 0 0 5 5 5 0 TrkA-N domain NAD_binding_7 PF13241.6 KFX92121.1 - 0.12 12.8 0.0 6.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 KFX92122.1 - 1.9e-13 50.1 32.6 3e-13 49.4 32.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFX92122.1 - 1.1e-09 38.2 7.4 1.1e-09 38.2 7.4 2.8 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 OppC_N PF12911.7 KFX92122.1 - 0.051 13.6 0.9 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C TGT PF01702.18 KFX92127.1 - 1.6e-27 96.6 0.0 1.8e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1279 PF06916.13 KFX92131.1 - 4.2e-10 40.0 0.0 5.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SET PF00856.28 KFX92136.1 - 1.6e-13 51.4 3.6 2.7e-13 50.7 0.2 2.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFX92136.1 - 8.4e-10 38.5 3.0 8.4e-10 38.5 3.0 1.9 2 0 0 2 2 2 1 AWS domain B12D PF06522.11 KFX92137.1 - 0.00028 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PRP21_like_P PF12230.8 KFX92138.1 - 5.3e-54 183.4 15.9 1.9e-53 181.5 15.9 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KFX92138.1 - 3.4e-40 135.8 3.7 1.7e-19 69.5 0.2 2.7 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KFX92138.1 - 0.0037 16.8 0.3 0.0083 15.7 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Toprim_Crpt PF13342.6 KFX92138.1 - 0.078 13.0 0.2 10 6.2 0.1 2.6 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase PMT PF02366.18 KFX92139.1 - 2.5e-77 259.8 14.6 3.7e-77 259.2 14.6 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFX92139.1 - 8.3e-68 227.9 11.8 8.3e-68 227.9 11.8 2.6 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFX92139.1 - 1.3e-43 149.0 0.0 2.9e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 MIR domain Mito_carr PF00153.27 KFX92140.1 - 4.2e-69 228.6 1.9 1.2e-22 79.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX92140.1 - 0.01 15.0 0.9 0.83 8.8 0.0 2.8 2 1 0 2 2 2 0 Gammaproteobacterial serine protease GPI-anchored PF10342.9 KFX92145.1 - 2.4e-11 44.2 0.0 6.6e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KFX92146.1 - 6.1e-20 71.8 0.4 6.1e-20 71.8 0.4 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 KFX92146.1 - 0.38 9.3 2.1 0.42 9.1 2.1 1.0 1 0 0 1 1 1 0 Macoilin family DREPP PF05558.12 KFX92146.1 - 2 8.3 9.0 2.8 7.8 9.0 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide SOG2 PF10428.9 KFX92146.1 - 2.6 7.2 14.6 2.8 7.0 14.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 KFX92146.1 - 5 5.8 5.5 5.5 5.7 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AF-4 PF05110.13 KFX92146.1 - 8.9 4.2 17.5 10 4.0 17.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Opy2 PF09463.10 KFX92149.1 - 8.5e-09 35.6 24.6 1.3e-08 35.0 24.6 1.3 1 0 0 1 1 1 1 Opy2 protein zf-CCCH_4 PF18044.1 KFX92149.1 - 0.082 12.7 0.7 0.15 11.9 0.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger DUF5305 PF17231.2 KFX92149.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Chitin_synth_1 PF01644.17 KFX92150.1 - 3.5e-69 231.9 0.1 5.3e-69 231.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFX92150.1 - 1.1e-28 99.0 0.1 3.6e-28 97.3 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFX92150.1 - 8.1e-23 80.8 1.0 1.4e-18 66.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFX92150.1 - 1.7e-08 34.6 0.0 1.7e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 UQ_con PF00179.26 KFX92151.1 - 6.2e-39 132.9 0.0 7.9e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IlvN PF07991.12 KFX92152.1 - 4.2e-45 153.3 0.1 6.3e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KFX92152.1 - 2.9e-40 137.9 0.0 4.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pkinase PF00069.25 KFX92159.1 - 2.4e-33 115.6 0.0 1.2e-32 113.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92159.1 - 1.2e-22 80.4 0.0 3.8e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX92159.1 - 0.072 12.4 0.4 0.27 10.6 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX92159.1 - 0.086 12.7 0.2 0.28 11.0 0.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family SWI-SNF_Ssr4 PF08549.10 KFX92168.1 - 1.1e-237 791.3 6.0 1.4e-237 790.9 6.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DUF4407 PF14362.6 KFX92168.1 - 0.24 10.7 0.4 0.42 9.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 KFX92168.1 - 0.69 9.8 8.2 0.049 13.6 2.1 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit HNH_2 PF13391.6 KFX92171.1 - 5.9e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Beta-lactamase PF00144.24 KFX92172.1 - 8.8e-39 133.6 0.1 1.2e-38 133.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KFX92173.1 - 6.7e-10 38.3 0.3 1.5e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92173.1 - 2.9e-07 30.5 10.1 4.8e-07 29.8 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KFX92174.1 - 1.3e-47 162.7 0.0 1.8e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KFX92174.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 2 0 0 2 2 2 0 PIG-X / PBN1 IBN_N PF03810.19 KFX92175.1 - 2.6e-09 36.9 0.0 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFX92175.1 - 0.018 15.1 0.0 0.087 12.9 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein HORMA PF02301.18 KFX92176.1 - 8e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 HORMA domain CorA PF01544.18 KFX92179.1 - 3e-40 138.4 0.1 6.6e-40 137.3 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TBCA PF02970.16 KFX92180.1 - 2.7e-25 88.5 12.7 2.7e-25 88.5 12.7 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A MHCassoc_trimer PF08831.10 KFX92180.1 - 0.012 15.6 0.1 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF2089 PF09862.9 KFX92180.1 - 0.018 15.1 3.0 0.29 11.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) DUF4239 PF14023.6 KFX92180.1 - 0.039 13.7 4.4 0.047 13.4 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) D123 PF07065.14 KFX92180.1 - 0.041 13.0 2.2 0.049 12.8 2.2 1.1 1 0 0 1 1 1 0 D123 Dynamin_M PF01031.20 KFX92180.1 - 0.055 12.7 0.3 0.055 12.7 0.3 2.0 1 1 1 2 2 2 0 Dynamin central region YkyA PF10368.9 KFX92180.1 - 0.056 13.1 19.3 0.027 14.2 14.6 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF2408 PF10303.9 KFX92180.1 - 0.064 13.8 4.1 0.076 13.6 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FapA PF03961.13 KFX92180.1 - 0.23 10.0 8.9 0.27 9.8 8.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KFX92180.1 - 0.38 9.6 14.4 0.56 9.0 14.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KFX92180.1 - 0.39 8.6 8.1 0.44 8.4 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlbE PF14003.6 KFX92180.1 - 0.46 10.9 3.5 2 8.9 1.1 2.2 1 1 2 3 3 3 0 YlbE-like protein TFR_dimer PF04253.15 KFX92180.1 - 1.1 9.4 5.5 0.5 10.5 1.0 2.1 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain DASH_Spc19 PF08287.11 KFX92180.1 - 1.3 8.9 12.8 1.4 8.8 10.6 1.9 1 1 1 2 2 2 0 Spc19 HSP70 PF00012.20 KFX92180.1 - 1.4 7.0 10.7 1.6 6.8 10.7 1.0 1 0 0 1 1 1 0 Hsp70 protein Uso1_p115_C PF04871.13 KFX92180.1 - 2 8.8 19.2 0.34 11.3 5.6 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF883 PF05957.13 KFX92180.1 - 2.5 8.8 8.5 16 6.2 8.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CCDC-167 PF15188.6 KFX92180.1 - 6.6 7.2 16.7 9.8 6.6 2.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Importin_rep_3 PF18806.1 KFX92183.1 - 0.043 13.9 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Importin 13 repeat Bombinin PF05298.11 KFX92183.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Bombinin Fungal_trans PF04082.18 KFX92184.1 - 5.9e-07 28.8 0.4 2.3e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92184.1 - 2.2e-06 27.7 10.0 4.8e-06 26.6 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PWI PF01480.17 KFX92185.1 - 6.6e-14 52.0 0.1 1.5e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_Rrp7 PF17799.1 KFX92185.1 - 0.021 14.6 0.2 0.052 13.4 0.2 1.6 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DUF445 PF04286.12 KFX92185.1 - 7.5 6.2 14.9 1.1 9.0 10.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Ribosomal_S21 PF01165.20 KFX92186.1 - 5.2e-13 48.5 1.7 1.1e-12 47.4 1.7 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Rhodanese PF00581.20 KFX92186.1 - 7.1e-07 29.7 0.3 1.4e-05 25.5 0.3 2.3 1 1 0 1 1 1 1 Rhodanese-like domain Androgen_recep PF02166.16 KFX92187.1 - 0.69 8.7 10.5 0.94 8.3 10.5 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 KFX92187.1 - 1.3 8.5 11.0 1.9 8.0 11.0 1.1 1 0 0 1 1 1 0 Spt20 family BAR_2 PF10455.9 KFX92188.1 - 7.8e-16 58.0 0.1 9.8e-16 57.7 0.1 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFX92188.1 - 3.2e-10 40.0 0.1 3.8e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFX92188.1 - 0.0037 17.0 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 BAR domain of APPL family Zn_clus PF00172.18 KFX92192.1 - 1.4e-09 38.0 10.2 2e-09 37.4 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX92192.1 - 9.2e-06 24.7 0.1 1.5e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.21 KFX92193.1 - 1e-66 224.7 0.0 1.3e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFX92193.1 - 2.2e-09 37.1 0.0 4.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Kinesin PF00225.23 KFX92195.1 - 1.1e-79 267.8 0.0 1.6e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX92195.1 - 4.7e-21 75.3 0.0 8.8e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 KFX92195.1 - 0.00095 19.7 0.2 0.0048 17.5 0.2 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KFX92195.1 - 0.01 15.7 0.3 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_3 PF12836.7 KFX92195.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PBP1_TM PF14812.6 KFX92195.1 - 0.033 14.6 1.9 0.094 13.1 1.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MIT PF04212.18 KFX92195.1 - 0.2 11.7 1.2 0.42 10.7 0.1 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Efg1 PF10153.9 KFX92195.1 - 1.7 9.1 5.2 26 5.2 1.2 2.5 1 1 1 2 2 2 0 rRNA-processing protein Efg1 UCH PF00443.29 KFX92200.1 - 1.5e-55 188.5 0.0 1.9e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX92200.1 - 5.1e-26 92.0 0.7 4e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KFX92200.1 - 0.0016 18.0 3.4 0.076 12.5 0.7 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Methyltransf_25 PF13649.6 KFX92208.1 - 2.7e-11 44.0 0.0 8.9e-11 42.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92208.1 - 5.5e-11 43.0 0.0 1.1e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX92208.1 - 5.1e-10 39.4 0.0 7.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92208.1 - 5.5e-06 26.3 0.0 3.2e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX92208.1 - 2.3e-05 25.0 0.0 0.00011 22.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX92208.1 - 0.0002 20.8 0.0 0.00084 18.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFX92208.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase KH_8 PF17903.1 KFX92210.1 - 1.3e-29 102.1 0.0 3.2e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFX92210.1 - 0.014 15.2 0.3 0.059 13.2 0.0 2.2 2 1 0 2 2 2 0 KH domain DEAD PF00270.29 KFX92213.1 - 2e-50 171.0 0.0 1.9e-49 167.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX92213.1 - 1.4e-26 93.0 0.0 6e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX92213.1 - 0.0006 19.9 0.0 0.008 16.2 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 KFX92214.1 - 2.1e-13 50.4 3.2 4.6e-09 36.6 0.6 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX92214.1 - 1e-10 42.1 9.3 3e-07 30.9 0.0 3.0 3 1 0 3 3 3 2 HMG-box domain DUF2561 PF10812.8 KFX92214.1 - 1.8 8.6 7.1 0.88 9.6 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF5521 PF17659.1 KFX92214.1 - 6.9 4.4 8.1 5.6 4.7 4.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5521) HAT PF02184.16 KFX92215.1 - 2.8e-26 91.2 69.6 3.2e-12 46.2 1.6 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFX92215.1 - 3.8e-21 74.0 33.5 0.0012 19.4 0.2 12.0 7 3 5 12 12 12 7 Tetratricopeptide repeat TPR_19 PF14559.6 KFX92215.1 - 1.3e-19 70.4 2.9 1.4e-05 25.5 0.0 7.3 6 1 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 KFX92215.1 - 9.2e-13 48.8 23.5 6.1e-05 23.1 1.5 6.1 2 1 3 6 6 6 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KFX92215.1 - 1.6e-10 40.3 24.1 0.51 10.6 0.0 10.8 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX92215.1 - 6.1e-07 29.4 7.0 0.041 14.3 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX92215.1 - 1.9e-06 27.6 10.6 5.1 7.6 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KFX92215.1 - 1.6e-05 24.8 21.7 0.046 13.8 1.3 7.1 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 KFX92215.1 - 0.00083 19.8 20.5 8.5 7.3 0.0 9.2 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX92215.1 - 0.0016 19.0 14.1 24 5.7 0.0 8.2 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_15 PF13429.6 KFX92215.1 - 0.0019 17.4 18.6 0.067 12.4 2.9 5.0 1 1 4 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFX92215.1 - 0.0067 16.4 17.7 1.9 8.5 1.1 6.3 5 1 0 5 5 5 1 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 KFX92215.1 - 0.049 12.8 25.0 1.4 8.0 1.6 5.6 3 3 2 5 5 5 0 NRDE-2, necessary for RNA interference Fis1_TPR_C PF14853.6 KFX92215.1 - 0.071 13.2 9.6 37 4.5 0.7 5.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PBP_GOBP PF01395.22 KFX92215.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 PBP/GOBP family ANAPC3 PF12895.7 KFX92215.1 - 0.16 12.2 7.5 1.5 9.1 0.0 5.1 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFX92215.1 - 1.7 9.0 28.2 3.4 8.0 0.1 8.1 10 1 0 10 10 9 0 Tetratricopeptide repeat GST_N_3 PF13417.6 KFX92216.1 - 6.6e-18 64.9 0.1 4e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX92216.1 - 6e-12 45.7 1.1 1.1e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX92216.1 - 1.2e-06 28.8 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX92216.1 - 3.9e-05 23.6 0.1 9.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFX92216.1 - 0.0014 19.1 0.0 0.0027 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetate_kinase PF00871.17 KFX92217.1 - 1.6e-82 277.3 0.1 4.7e-63 213.2 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family DUF3602 PF12223.8 KFX92221.1 - 5.1e-14 52.6 16.7 8.8e-12 45.5 2.9 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) DUF3712 PF12505.8 KFX92225.1 - 5.4e-21 75.1 1.4 5.4e-21 75.1 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) tRNA_bind PF01588.20 KFX92227.1 - 2.4e-21 75.7 0.1 4.5e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KFX92227.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KFX92228.1 - 2.7e-28 98.7 0.0 2.1e-27 95.9 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92228.1 - 2.1e-09 37.3 8.9 3.7e-09 36.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX92228.1 - 0.073 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain SEP PF08059.13 KFX92231.1 - 5.9e-22 78.0 0.1 9.4e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KFX92231.1 - 3.8e-09 36.6 0.0 5.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain Ank_2 PF12796.7 KFX92233.1 - 1.6e-68 227.2 1.6 1.4e-16 60.9 1.8 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX92233.1 - 4.3e-52 168.0 2.2 0.00041 20.6 0.0 12.3 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 KFX92233.1 - 3e-51 171.2 2.3 2e-09 37.8 0.0 9.3 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX92233.1 - 1.7e-48 161.0 1.3 0.00023 21.5 0.0 11.3 11 1 1 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 KFX92233.1 - 7.8e-42 140.8 4.6 1.4e-07 31.6 0.2 9.3 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Reductase_C PF14759.6 KFX92233.1 - 0.036 14.6 0.1 9.1 6.9 0.0 3.7 4 0 0 4 4 4 0 Reductase C-terminal Ank_4 PF13637.6 KFX92234.1 - 1.1e-09 38.6 0.9 2.6e-05 24.6 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92234.1 - 3.7e-09 36.1 0.6 3e-07 30.2 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KFX92234.1 - 2.3e-08 34.5 0.0 2.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX92234.1 - 3.7e-07 30.3 0.1 2.4e-06 27.7 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX92234.1 - 0.00038 20.8 1.1 0.00097 19.5 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat SesA PF17107.5 KFX92234.1 - 0.042 14.0 0.2 0.097 12.9 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RabGAP-TBC PF00566.18 KFX92239.1 - 8.6e-33 113.8 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ORMDL PF04061.14 KFX92247.1 - 4.6e-59 198.1 3.9 5.9e-59 197.7 3.9 1.1 1 0 0 1 1 1 1 ORMDL family DUF543 PF04418.12 KFX92248.1 - 9.3e-27 92.8 0.0 2.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-CCHC PF00098.23 KFX92248.1 - 1.5e-05 24.8 27.7 0.044 13.9 5.5 4.7 4 0 0 4 4 4 4 Zinc knuckle LOH1CR12 PF10158.9 KFX92250.1 - 0.00016 21.7 0.6 0.00048 20.2 0.3 1.9 1 1 0 2 2 2 1 Tumour suppressor protein MMR_HSR1_Xtn PF16897.5 KFX92250.1 - 0.091 12.8 0.3 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1_C PF08438.10 KFX92251.1 - 5.3e-35 120.4 0.0 8.8e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KFX92251.1 - 8.7e-22 77.4 0.0 3.1e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX92251.1 - 7.3e-10 38.6 0.1 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX92251.1 - 0.0018 18.4 0.8 0.12 12.4 0.1 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KFX92251.1 - 0.0042 16.7 0.3 0.81 9.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFX92251.1 - 0.0044 16.8 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein VirB8 PF04335.13 KFX92251.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein RsgA_GTPase PF03193.16 KFX92251.1 - 0.036 14.0 0.5 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFX92251.1 - 0.042 13.9 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AstB PF04996.12 KFX92251.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Succinylarginine dihydrolase KTI12 PF08433.10 KFX92251.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 KFX92251.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KFX92251.1 - 0.12 12.8 0.1 0.71 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SET PF00856.28 KFX92253.1 - 3.5e-08 34.0 0.0 1e-07 32.5 0.0 1.8 2 1 0 2 2 2 1 SET domain Fungal_trans PF04082.18 KFX92254.1 - 3.5e-28 98.4 0.8 6.5e-28 97.5 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92254.1 - 2e-08 34.2 14.9 4.5e-08 33.1 14.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KFX92254.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Spermine_synth PF01564.17 KFX92256.1 - 1e-75 253.3 0.0 1.5e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFX92256.1 - 2.4e-26 91.4 0.1 4.3e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFX92256.1 - 0.00019 22.0 0.0 0.00055 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 KFX92256.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KFX92256.1 - 0.0051 17.5 0.4 0.078 13.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFX92256.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFX92256.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Sporozoite_P67 PF05642.11 KFX92257.1 - 0.014 13.5 12.5 0.018 13.2 12.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lin-8 PF03353.15 KFX92257.1 - 0.31 10.6 4.7 0.52 9.8 4.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.9 KFX92257.1 - 0.96 8.6 9.4 1.1 8.4 9.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein BUD22 PF09073.10 KFX92257.1 - 1.2 8.4 8.0 1.6 8.0 8.0 1.2 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 KFX92257.1 - 1.4 6.0 6.0 1.8 5.6 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mucin PF01456.17 KFX92257.1 - 2.2 8.3 32.1 4.5 7.3 32.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop14 PF04147.12 KFX92257.1 - 4.8 5.3 9.6 6.2 4.9 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAD_binding_4 PF01565.23 KFX92258.1 - 1.3e-22 80.1 0.3 2.2e-22 79.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX92258.1 - 0.0053 16.8 0.2 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF2957 PF11170.8 KFX92258.1 - 0.046 12.6 0.2 0.79 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2957) Ldl_recept_a PF00057.18 KFX92260.1 - 0.05 13.8 0.5 0.05 13.8 0.5 1.9 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A BING4CT PF08149.11 KFX92260.1 - 2 8.3 6.4 5.8 6.8 3.1 2.9 2 0 0 2 2 2 0 BING4CT (NUC141) domain Endothelin PF00322.17 KFX92260.1 - 7.9 6.2 6.2 21 4.8 1.0 2.7 2 0 0 2 2 2 0 Endothelin family Ribosomal_L22e PF01776.17 KFX92261.1 - 5.7e-46 155.4 1.3 7.9e-46 154.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Tubulin PF00091.25 KFX92262.1 - 7.1e-68 228.7 0.0 1.1e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX92262.1 - 1.5e-45 154.4 0.1 3.4e-45 153.3 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Mito_carr PF00153.27 KFX92262.1 - 2.5e-39 133.1 3.0 1.1e-16 60.5 0.1 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein GDPD PF03009.17 KFX92262.1 - 5.2e-32 111.6 0.0 9.3e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.9 KFX92262.1 - 1.2e-06 28.8 0.0 2.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.6 KFX92262.1 - 3.8e-05 24.0 0.3 0.00012 22.4 0.3 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PIG-F PF06699.11 KFX92263.1 - 1.9e-50 171.5 2.9 3e-50 170.9 2.9 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.16 KFX92264.1 - 8.7e-51 172.8 0.0 1e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Translin family Amino_oxidase PF01593.24 KFX92266.1 - 7.8e-39 134.2 0.1 3.9e-29 102.2 0.0 2.3 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase Ank_4 PF13637.6 KFX92266.1 - 1.7e-11 44.4 0.1 7.5e-06 26.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NAD_binding_8 PF13450.6 KFX92266.1 - 3.3e-09 36.8 0.0 7.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KFX92266.1 - 1.1e-08 35.6 0.0 3.8e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX92266.1 - 1.2e-06 28.6 0.4 6.8e-05 23.1 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DAO PF01266.24 KFX92266.1 - 2.9e-06 27.1 0.0 5.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ank PF00023.30 KFX92266.1 - 4.3e-05 23.8 5.4 0.0049 17.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Pyr_redox_2 PF07992.14 KFX92266.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ank_3 PF13606.6 KFX92266.1 - 0.0012 19.1 0.2 1.4 9.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Thi4 PF01946.17 KFX92266.1 - 0.0027 17.0 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFX92266.1 - 0.0049 17.4 0.0 0.015 15.9 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX92266.1 - 0.0062 15.8 0.3 0.015 14.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX92266.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX92266.1 - 0.022 13.5 0.1 0.047 12.4 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX92266.1 - 0.04 13.2 0.1 0.08 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFX92266.1 - 0.068 13.1 0.2 0.23 11.3 0.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFX92266.1 - 0.091 11.8 0.9 0.16 11.0 0.9 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFX92266.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KFX92266.1 - 0.17 12.4 0.0 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding U3_snoRNA_assoc PF08297.11 KFX92269.1 - 8.5e-09 36.0 2.5 8.5e-09 36.0 2.5 5.1 3 2 0 3 3 3 1 U3 snoRNA associated ABM PF03992.16 KFX92269.1 - 0.00035 20.6 0.0 0.00094 19.2 0.0 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TPR_8 PF13181.6 KFX92270.1 - 4.2e-06 26.6 0.6 0.029 14.6 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX92270.1 - 5.3e-06 26.1 4.1 0.012 15.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX92270.1 - 1.2e-05 25.6 4.2 0.00062 20.0 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX92270.1 - 0.00012 22.5 4.2 0.055 14.1 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX92270.1 - 0.00028 21.5 1.0 0.033 14.8 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92270.1 - 0.016 15.0 5.8 0.95 9.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX92270.1 - 0.019 15.5 2.2 0.17 12.4 0.3 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Terminase_6C PF17289.2 KFX92270.1 - 0.02 15.0 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain ANAPC3 PF12895.7 KFX92270.1 - 0.062 13.5 0.2 0.25 11.6 0.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KFX92270.1 - 0.067 13.3 1.1 4.1 7.7 0.1 3.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX92270.1 - 0.068 14.0 6.4 1.1 10.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KFX92270.1 - 0.072 12.5 4.5 0.35 10.2 4.5 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KFX92270.1 - 0.093 12.6 2.3 0.49 10.3 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX92270.1 - 0.16 12.4 2.7 1.4 9.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX92270.1 - 0.18 11.6 3.7 0.29 10.8 0.1 3.1 3 1 0 3 3 3 0 TPR repeat NABP PF07990.12 KFX92273.1 - 0.0046 16.6 0.1 0.0057 16.2 0.1 1.1 1 0 0 1 1 1 1 Nucleic acid binding protein NABP DUF4761 PF15958.5 KFX92273.1 - 0.029 14.5 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Abhydrolase_3 PF07859.13 KFX92274.1 - 1.2e-26 93.9 0.0 1.7e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX92274.1 - 3.9e-19 68.7 0.0 9.9e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFX92274.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFX92274.1 - 0.057 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KFX92276.1 - 7.3e-32 111.0 0.3 8.8e-32 110.7 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX92276.1 - 8.1e-05 23.3 0.6 0.00012 22.8 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFX92276.1 - 0.047 12.6 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase SUR7 PF06687.12 KFX92290.1 - 5.6e-26 91.5 12.6 7.4e-26 91.1 12.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.13 KFX92290.1 - 0.027 13.7 2.2 0.044 13.0 2.2 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Pox_P21 PF05313.12 KFX92290.1 - 0.13 11.8 4.0 0.25 10.9 4.0 1.4 1 0 0 1 1 1 0 Poxvirus P21 membrane protein CoA_binding_3 PF13727.6 KFX92290.1 - 3.5 7.6 5.5 1.3 9.0 2.2 1.8 1 1 1 2 2 2 0 CoA-binding domain Bromodomain PF00439.25 KFX92303.1 - 3.8e-37 126.2 3.5 1.3e-19 70.0 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KFX92303.1 - 5.8e-16 58.5 0.9 5.8e-16 58.5 0.9 2.0 2 0 0 2 2 2 1 BAH domain SOG2 PF10428.9 KFX92303.1 - 0.34 10.0 11.4 0.53 9.4 11.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein AT_hook PF02178.19 KFX92303.1 - 2.2 8.4 8.9 0.17 11.9 1.2 3.3 2 0 0 2 2 2 0 AT hook motif HIT PF01230.23 KFX92305.1 - 3.3e-22 79.1 0.1 4.5e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFX92305.1 - 6e-12 46.0 0.0 9.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFX92305.1 - 2.1e-05 24.4 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 KFX92306.1 - 1.3e-39 135.5 0.0 2.2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX92306.1 - 1.2e-13 51.0 0.1 3.4e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFX92306.1 - 2.9e-07 30.7 0.0 6.9e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2057 PF09829.9 KFX92306.1 - 0.6 10.3 3.7 3.1 7.9 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DASH_Dam1 PF08653.10 KFX92307.1 - 0.008 16.0 1.4 0.01 15.6 0.5 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 INO80_Ies4 PF08193.11 KFX92307.1 - 0.01 15.8 1.6 0.011 15.7 1.6 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 zf-C2H2_jaz PF12171.8 KFX92308.1 - 1.5e-11 44.3 1.3 3.1e-11 43.2 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFX92308.1 - 0.00099 18.8 0.2 0.0025 17.5 0.2 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 KFX92308.1 - 0.0018 18.6 0.6 0.0029 17.9 0.6 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFX92308.1 - 0.013 15.9 1.0 0.025 14.9 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Papo_T_antigen PF02380.15 KFX92308.1 - 0.089 12.9 0.3 0.25 11.5 0.1 1.7 1 1 1 2 2 2 0 T-antigen specific domain Aconitase PF00330.20 KFX92309.1 - 3.1e-150 501.2 0.0 3.9e-150 500.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFX92309.1 - 1.3e-43 148.5 0.0 2.5e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.22 KFX92310.1 - 2.3e-15 56.9 8.5 2.3e-15 56.9 8.5 1.7 2 0 0 2 2 2 1 Rhomboid family DUF2070 PF09843.9 KFX92310.1 - 0.16 10.3 9.6 0.2 9.9 9.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gaa1 PF04114.14 KFX92311.1 - 2.1e-174 581.2 2.3 2.5e-174 581.0 2.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Phage_holin_3_2 PF04550.12 KFX92311.1 - 0.1 13.2 0.5 1.5 9.4 0.1 2.7 2 0 0 2 2 2 0 Phage holin family 2 PCI PF01399.27 KFX92312.1 - 8.9e-09 35.8 0.0 1.9e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KFX92312.1 - 0.00086 18.8 1.1 0.0017 17.9 1.1 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KFX92312.1 - 0.038 13.6 0.1 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 DNA N-6-adenine-methyltransferase (Dam) N6-adenineMlase PF10237.9 KFX92313.1 - 1.9e-52 177.3 0.1 9.2e-52 175.1 0.1 2.0 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NmrA PF05368.13 KFX92313.1 - 6.1e-17 62.0 0.0 1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFX92313.1 - 6.5e-15 55.3 0.1 1.2e-14 54.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX92313.1 - 1.3e-13 51.2 0.0 2.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX92313.1 - 1.7e-10 40.3 0.0 3.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX92313.1 - 4.3e-08 32.9 0.1 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFX92313.1 - 3.4e-07 29.6 0.0 5.1e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFX92313.1 - 0.00028 20.4 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KFX92313.1 - 0.00047 19.4 0.4 0.035 13.3 0.4 2.8 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KFX92313.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RXLR PF16810.5 KFX92313.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Polysacc_synt_2 PF02719.15 KFX92313.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KFX92313.1 - 0.071 13.0 0.0 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 KR domain UCH PF00443.29 KFX92314.1 - 6.2e-25 88.2 2.6 2e-17 63.5 0.5 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX92314.1 - 2.5e-08 33.9 13.8 9.1e-07 28.8 11.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFX92314.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 2.8 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf_C2H2_ZHX PF18387.1 KFX92314.1 - 0.043 13.5 0.7 0.8 9.4 0.0 2.7 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain BLACT_WH PF17778.1 KFX92315.1 - 2.7e-16 59.3 0.2 5.2e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KFX92315.1 - 2e-12 47.6 3.5 2.7e-10 40.6 3.5 2.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX92315.1 - 2.6e-05 23.8 0.1 4.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFX92315.1 - 0.042 13.7 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain I-set PF07679.16 KFX92316.1 - 0.00015 21.8 0.1 2.9 8.0 0.1 4.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.11 KFX92316.1 - 0.07 12.8 0.8 6.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) MAP70 PF07058.11 KFX92316.1 - 0.11 11.2 0.2 0.17 10.6 0.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF4265 PF14085.6 KFX92316.1 - 0.13 12.3 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Peptidase_C12 PF01088.21 KFX92317.1 - 2.1e-52 177.9 0.0 1.5e-50 171.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFX92317.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases YccV-like PF08755.11 KFX92318.1 - 2.1e-28 98.7 0.2 4.5e-28 97.6 0.2 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KFX92318.1 - 2.2e-17 63.0 0.0 4.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KFX92318.1 - 1.2e-08 34.7 0.5 3.2e-08 33.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX92318.1 - 0.00023 20.9 0.0 0.00056 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFX92318.1 - 0.017 15.7 0.1 0.046 14.3 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_5 PF18511.1 KFX92318.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 F-box SPX PF03105.19 KFX92319.1 - 4.6e-55 188.1 0.4 6.8e-55 187.5 0.4 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KFX92319.1 - 8.7e-08 31.9 8.3 1.5e-07 31.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX92319.1 - 1.6e-06 27.8 12.7 3.3e-06 26.9 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX92319.1 - 2.1e-06 27.5 11.6 4.1e-06 26.5 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX92319.1 - 4.6e-06 26.7 11.4 1e-05 25.6 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX92319.1 - 9.6e-06 25.8 10.9 1.7e-05 25.1 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX92319.1 - 4e-05 23.5 9.9 7.9e-05 22.5 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX92319.1 - 0.00096 19.1 8.4 0.0022 18.0 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFX92319.1 - 0.01 15.7 9.0 0.024 14.5 9.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFX92319.1 - 0.018 14.9 3.9 0.018 14.9 3.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFX92319.1 - 0.031 14.6 6.2 0.076 13.3 6.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFX92319.1 - 0.13 12.4 2.6 0.23 11.5 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.12 KFX92319.1 - 0.38 10.8 3.5 4.8 7.2 3.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-Nse PF11789.8 KFX92319.1 - 1.7 8.5 7.4 3.5 7.5 7.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFX92319.1 - 1.9 8.4 6.0 3.6 7.5 5.2 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFX92319.1 - 7.9 6.2 8.8 1.2e+02 2.5 9.1 2.2 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.31 KFX92320.1 - 7e-24 83.7 0.4 1.9e-23 82.4 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KFX92320.1 - 4.8e-09 36.3 4.3 4.8e-09 36.3 4.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFX92320.1 - 9.5e-08 32.3 4.3 0.0019 18.5 1.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFX92320.1 - 6.9e-07 29.5 2.9 6.9e-07 29.5 2.9 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFX92320.1 - 0.0015 19.2 2.4 2.1 9.4 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX92320.1 - 0.0018 18.6 5.5 0.19 12.2 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 KFX92320.1 - 0.01 15.7 0.1 0.043 13.7 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein HNH_5 PF14279.6 KFX92320.1 - 0.61 10.0 3.8 4.3 7.3 0.6 2.5 2 0 0 2 2 2 0 HNH endonuclease DUF678 PF05077.12 KFX92320.1 - 0.63 10.2 5.2 0.17 12.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) PSCyt3 PF07627.11 KFX92320.1 - 0.75 10.1 4.2 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Peptidase_C54 PF03416.19 KFX92321.1 - 5.8e-93 311.3 0.0 7e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 KFX92322.1 - 1.4e-11 44.2 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KFX92322.1 - 6.3e-10 38.8 0.9 6.3e-10 38.8 0.9 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KFX92322.1 - 0.0019 18.3 2.8 0.0025 17.8 0.3 2.5 2 0 0 2 2 2 1 G-patch domain Histone PF00125.24 KFX92323.1 - 1.2e-22 80.7 2.0 1.5e-22 80.4 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFX92323.1 - 4.1e-05 23.8 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFX92323.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KFX92323.1 - 0.025 14.2 0.1 0.057 13.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KFX92324.1 - 1.1e-20 73.1 3.1 1.9e-20 72.3 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFX92324.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFX92324.1 - 9.7e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 KFX92325.1 - 1.3e-08 34.7 1.6 1.9e-08 34.2 1.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 KFX92326.1 - 5.3e-78 261.7 0.0 7.9e-78 261.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFX92326.1 - 4.6e-16 58.4 1.1 8.3e-16 57.6 1.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme SAGA-Tad1 PF12767.7 KFX92326.1 - 0.08 12.7 3.6 0.13 12.0 3.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM76 PF16046.5 KFX92326.1 - 0.29 10.4 5.5 3.8 6.8 3.9 2.0 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 KFX92326.1 - 0.48 9.1 5.7 0.67 8.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KFX92326.1 - 1.5 7.4 7.9 2 7.0 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KFX92326.1 - 3.3 6.5 7.5 4.6 6.0 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KFX92326.1 - 5 5.3 5.8 6.5 4.9 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CDP-OH_P_transf PF01066.21 KFX92332.1 - 1.5e-13 51.3 0.2 3.9e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OTU PF02338.19 KFX92332.1 - 9.8e-07 29.3 0.0 1.7e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFX92332.1 - 0.18 11.2 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain EI24 PF07264.11 KFX92333.1 - 1.4e-14 54.7 2.6 1.3e-11 45.1 2.6 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 KFX92334.1 - 9.6e-41 139.0 0.0 2.6e-40 137.6 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Mog1 PF04603.12 KFX92335.1 - 1e-39 136.1 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 KFX92336.1 - 3.8e-39 133.1 0.1 6.2e-39 132.4 0.1 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KFX92336.1 - 1.3e-06 28.2 3.9 2.5e-06 27.3 3.9 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Glyco_hydro_72 PF03198.14 KFX92337.1 - 2.9e-132 440.7 3.9 4e-132 440.2 3.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KFX92337.1 - 5.7e-26 91.0 7.3 5.7e-26 91.0 7.3 2.1 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.17 KFX92337.1 - 0.049 12.7 0.2 0.44 9.6 0.2 2.2 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glucan_synthase PF02364.15 KFX92338.1 - 0 1382.3 0.0 0 1381.7 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFX92338.1 - 2.2e-43 147.7 1.2 6.7e-43 146.1 1.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 XhlA PF10779.9 KFX92338.1 - 0.24 11.6 1.0 0.79 10.0 1.0 1.9 1 0 0 1 1 1 0 Haemolysin XhlA Aminotran_1_2 PF00155.21 KFX92340.1 - 5.9e-35 121.1 0.0 9e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFX92340.1 - 0.012 14.2 0.0 0.023 13.2 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Zip PF02535.22 KFX92347.1 - 3.9e-08 32.9 0.9 3.9e-08 32.9 0.9 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter SieB PF14163.6 KFX92347.1 - 0.018 14.5 1.3 1.4 8.4 0.2 2.4 2 0 0 2 2 2 0 Super-infection exclusion protein B DctQ PF04290.12 KFX92347.1 - 0.043 13.7 2.4 0.11 12.4 1.2 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component CrgA PF06781.12 KFX92347.1 - 0.13 12.4 0.1 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Cell division protein CrgA RMI1_N PF08585.12 KFX92354.1 - 0.13 12.1 1.8 0.19 11.5 1.8 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein Plus-3 PF03126.18 KFX92359.1 - 1.3e-29 102.9 0.0 4.4e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain HMG_box PF00505.19 KFX92362.1 - 2.1e-06 28.0 0.0 5.5e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX92362.1 - 0.005 17.4 0.0 0.018 15.6 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain DHDPS PF00701.22 KFX92373.1 - 3.9e-27 94.7 0.0 4.8e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family RNA_pol PF00940.19 KFX92375.1 - 1.5e-173 577.5 0.2 2.4e-173 576.8 0.2 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFX92375.1 - 1.4e-102 343.5 5.0 2.4e-102 342.8 5.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RsfS PF02410.15 KFX92376.1 - 4.7e-14 52.6 0.0 1.3e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CENP_C_N PF15622.6 KFX92376.1 - 0.048 13.1 0.4 0.081 12.4 0.4 1.3 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Acetyltransf_1 PF00583.25 KFX92377.1 - 1.5e-18 67.1 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX92377.1 - 8.8e-14 51.5 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX92377.1 - 6.4e-12 45.7 0.0 9.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFX92377.1 - 1.2e-07 32.5 0.0 1.5e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX92377.1 - 8.7e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFX92377.1 - 4.6e-05 23.5 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KFX92377.1 - 0.0018 18.4 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 KFX92377.1 - 0.034 14.0 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX92377.1 - 0.059 13.4 0.0 0.41 10.7 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AstA PF04958.12 KFX92377.1 - 0.13 10.8 0.0 0.55 8.7 0.0 1.8 1 1 1 2 2 2 0 Arginine N-succinyltransferase beta subunit Acetyltransf_15 PF17013.5 KFX92377.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase DUF3636 PF12331.8 KFX92378.1 - 2.1e-49 167.2 0.0 4.4e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) TPR_MLP1_2 PF07926.12 KFX92378.1 - 0.96 9.5 17.7 2.7 8.1 17.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CTP_transf_1 PF01148.20 KFX92379.1 - 2.2e-81 273.5 25.0 2.8e-81 273.2 25.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.23 KFX92380.1 - 1.7e-70 237.3 1.0 2.4e-70 236.9 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX92380.1 - 7e-40 135.5 0.2 1.6e-39 134.4 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFX92380.1 - 0.0011 18.8 0.4 0.36 10.7 0.3 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFX92380.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KFX92380.1 - 0.084 12.4 2.6 0.16 11.5 1.6 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Sulfate_transp PF00916.20 KFX92381.1 - 2.5e-83 280.0 8.8 3.2e-83 279.6 8.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFX92381.1 - 1.2e-14 54.0 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFX92381.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KFX92381.1 - 5.8 7.4 16.7 0.043 14.2 3.6 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF3488 PF11992.8 KFX92381.1 - 6.9 5.5 7.5 6 5.7 5.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Adaptin_N PF01602.20 KFX92382.1 - 2.4e-125 419.1 7.7 3e-125 418.7 7.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFX92382.1 - 1.8e-55 187.4 0.1 1.8e-55 187.4 0.1 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX92382.1 - 4.7e-15 55.7 4.4 9.4e-05 22.7 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KFX92382.1 - 8.8e-12 44.2 2.3 0.00063 19.8 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFX92382.1 - 8.4e-07 29.4 3.8 0.64 10.6 0.1 6.2 6 0 0 6 6 6 2 HEAT-like repeat Arm PF00514.23 KFX92382.1 - 0.00032 20.6 0.3 4 7.6 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFX92382.1 - 0.0011 19.0 0.1 11 6.1 0.0 4.7 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KFX92382.1 - 0.0029 17.2 2.4 1.8 8.1 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KFX92382.1 - 0.043 14.0 0.8 5 7.3 0.0 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KFX92382.1 - 0.25 11.1 3.8 4.2 7.1 0.2 3.2 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 KFX92383.1 - 3.2e-49 165.9 2.4 3.8e-49 165.6 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) EMP70 PF02990.16 KFX92383.1 - 0.056 12.1 0.2 0.062 12.0 0.2 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 ADH_zinc_N PF00107.26 KFX92384.1 - 5.8e-20 71.6 0.4 9.2e-20 70.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX92384.1 - 2.6e-08 35.0 0.0 4.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GYF PF02213.16 KFX92385.1 - 1.8e-16 59.5 0.6 3.9e-16 58.4 0.6 1.6 1 0 0 1 1 1 1 GYF domain Amidase PF01425.21 KFX92388.1 - 1.7e-61 208.6 1.7 2.1e-61 208.3 1.7 1.0 1 0 0 1 1 1 1 Amidase Lentivirus_VIF PF05851.11 KFX92388.1 - 8.1e-05 21.6 0.0 0.0001 21.3 0.0 1.1 1 0 0 1 1 1 1 Lentivirus virion infectivity factor (VIF) RRM_1 PF00076.22 KFX92393.1 - 1.3e-07 31.3 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.23 KFX92396.1 - 1.2e-104 350.2 0.1 1.5e-104 349.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CLP1_P PF16575.5 KFX92396.1 - 5.1e-33 114.5 0.0 1.6e-32 112.9 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop TAXi_N PF14543.6 KFX92396.1 - 7.6e-15 55.6 0.5 3.2e-13 50.3 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX92396.1 - 0.011 16.3 0.1 16 6.2 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KFX92396.1 - 0.02 14.7 0.0 0.084 12.7 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal AAA_22 PF13401.6 KFX92396.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX92396.1 - 0.12 12.6 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX92396.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Mrx7 PF10906.8 KFX92397.1 - 2.5e-11 43.6 0.0 6.7e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 KFX92398.1 - 6.2e-46 156.9 0.0 9e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX92398.1 - 0.0033 17.2 0.0 0.0094 15.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFX92398.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFX92398.1 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family SMC_N PF02463.19 KFX92399.1 - 1.2e-74 250.5 9.8 4.2e-74 248.7 9.8 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX92399.1 - 1.6e-23 83.3 0.0 5.1e-23 81.6 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFX92399.1 - 9.3e-11 42.1 6.4 4.7e-05 23.3 0.4 3.5 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX92399.1 - 1.1e-08 35.8 8.0 1.1e-08 35.8 8.0 6.7 2 2 1 3 3 1 1 AAA domain Tektin PF03148.14 KFX92399.1 - 9.2e-05 21.4 13.2 9.2e-05 21.4 13.2 6.6 2 2 2 5 5 3 1 Tektin family AAA_29 PF13555.6 KFX92399.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KFX92399.1 - 0.0029 17.8 10.9 0.0029 17.8 10.9 7.4 2 2 4 7 7 6 3 Tropomyosin like Taxilin PF09728.9 KFX92399.1 - 0.0029 16.8 40.9 0.0029 16.8 40.9 4.5 3 1 0 3 3 2 1 Myosin-like coiled-coil protein DivIC PF04977.15 KFX92399.1 - 0.017 14.9 0.6 0.017 14.9 0.6 10.6 8 5 5 13 13 13 0 Septum formation initiator Laminin_II PF06009.12 KFX92399.1 - 0.017 15.1 0.8 0.017 15.1 0.8 8.5 2 2 8 11 11 10 0 Laminin Domain II Plasmid_RAQPRD PF09686.10 KFX92399.1 - 0.028 14.6 0.7 0.028 14.6 0.7 4.2 4 1 0 4 4 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) GAS PF13851.6 KFX92399.1 - 0.088 12.1 124.2 0.0089 15.4 9.7 7.6 2 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 KFX92399.1 - 2 9.0 0.0 2 9.0 0.0 6.3 3 2 0 3 3 1 0 ABC transporter DUF3644 PF12358.8 KFX92399.1 - 2.2 8.8 8.6 0.19 12.3 0.8 3.3 3 0 0 3 3 2 0 Protein of unknown function (DUF3644) AAA_13 PF13166.6 KFX92399.1 - 4.3 5.8 98.9 0.06 12.0 31.9 5.7 2 2 4 6 6 6 0 AAA domain ELYS PF13934.6 KFX92400.1 - 3e-63 213.8 0.7 3.7e-63 213.5 0.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-CCCH_4 PF18044.1 KFX92401.1 - 3.9e-06 26.5 4.7 7.3e-06 25.7 4.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFX92401.1 - 4.4e-05 23.4 8.2 8e-05 22.6 8.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFX92401.1 - 0.00012 21.8 1.4 0.00024 20.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFX92401.1 - 0.0031 18.2 0.3 0.0063 17.2 0.3 1.5 1 0 0 1 1 1 1 Torus domain Ribosomal_S10 PF00338.22 KFX92402.1 - 1e-27 96.2 0.3 1.2e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 KFX92403.1 - 2.3e-10 40.0 0.3 5.1e-10 38.8 0.3 1.6 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 KFX92403.1 - 0.021 14.1 4.6 0.037 13.3 4.6 1.3 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_18 PF00704.28 KFX92405.1 - 5.2e-86 289.2 0.1 5.2e-86 289.2 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DnaJ PF00226.31 KFX92405.1 - 6.1e-07 29.5 0.4 1.4e-06 28.3 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S27 PF01599.19 KFX92406.1 - 1e-26 92.8 2.2 1e-26 92.8 2.2 2.7 4 0 0 4 4 4 1 Ribosomal protein S27a IBR PF01485.21 KFX92406.1 - 0.015 15.5 1.7 0.036 14.3 0.2 2.3 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain Ribosomal_S26e PF01283.19 KFX92407.1 - 1.2e-51 173.7 7.0 1.4e-51 173.4 7.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KFX92407.1 - 0.021 14.8 0.5 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 KFX92407.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_2 PF12797.7 KFX92407.1 - 0.15 12.2 2.7 0.36 11.0 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4668 PF15701.5 KFX92407.1 - 0.17 11.7 0.4 0.26 11.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) SF1-HH PF16275.5 KFX92407.1 - 0.33 11.3 2.9 0.52 10.7 2.9 1.5 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Prenylcys_lyase PF07156.14 KFX92408.1 - 2.9e-90 303.0 0.0 4e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KFX92408.1 - 4.6e-14 52.6 0.0 1.5e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX92408.1 - 4.6e-13 49.2 0.0 9.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX92408.1 - 1.7e-09 37.7 0.1 1.4e-06 28.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX92408.1 - 0.00013 21.3 0.0 0.0033 16.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX92408.1 - 0.00014 21.9 0.1 0.00064 19.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFX92408.1 - 0.0053 16.0 0.1 0.01 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFX92408.1 - 0.0059 17.1 0.1 0.23 12.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX92408.1 - 0.033 13.8 0.2 0.1 12.2 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cpn60_TCP1 PF00118.24 KFX92409.1 - 1.1e-158 528.9 0.1 1.3e-158 528.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KFX92409.1 - 0.026 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like ECH_1 PF00378.20 KFX92410.1 - 4e-39 134.4 0.7 3.8e-36 124.7 0.4 2.9 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX92410.1 - 1.4e-27 97.1 0.2 1.6e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Ank_4 PF13637.6 KFX92411.1 - 1.2e-14 54.4 0.7 1.7e-08 34.8 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX92411.1 - 3.3e-14 53.2 0.1 4.3e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFX92411.1 - 3e-12 46.4 0.4 4.1e-08 33.3 0.6 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFX92411.1 - 1.2e-11 44.6 0.7 1.1e-08 35.1 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92411.1 - 5e-11 41.8 0.0 1.1e-05 25.4 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat ANAPC1 PF12859.7 KFX92412.1 - 6e-38 130.4 0.6 6e-38 130.4 0.6 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 DUF155 PF02582.14 KFX92413.1 - 1.1e-46 159.2 0.0 1.6e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LELP1 PF15042.6 KFX92413.1 - 0.074 13.5 1.3 0.13 12.7 1.3 1.3 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Cupin_1 PF00190.22 KFX92413.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Cupin Glyco_transf_92 PF01697.27 KFX92415.1 - 5.9e-09 36.0 0.0 8.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFX92415.1 - 3.9e-08 33.7 0.1 6.1e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 FAD_binding_4 PF01565.23 KFX92416.1 - 1.5e-21 76.6 3.1 2.8e-21 75.7 3.1 1.5 1 0 0 1 1 1 1 FAD binding domain LANC_like PF05147.13 KFX92416.1 - 3.2e-17 62.2 0.0 9.2e-17 60.6 0.0 1.6 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein BBE PF08031.12 KFX92416.1 - 2e-09 37.4 0.6 4.9e-09 36.1 0.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.25 KFX92417.1 - 2e-08 34.5 0.0 3.6e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX92417.1 - 1.2e-07 31.8 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX92417.1 - 5.9e-07 29.8 0.0 1.6e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX92417.1 - 0.0026 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFX92417.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 KFX92418.1 - 4.2e-13 50.4 11.8 4.2e-13 50.4 11.8 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX92418.1 - 1.5e-09 37.9 0.1 2.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Histone PF00125.24 KFX92418.1 - 1e-06 29.1 1.7 6.3e-06 26.6 0.9 2.2 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Hydrolase_4 PF12146.8 KFX92418.1 - 0.00056 19.2 0.0 0.36 10.1 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFX92418.1 - 0.024 14.5 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3089 PF11288.8 KFX92418.1 - 0.043 13.4 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_M28 PF04389.17 KFX92419.1 - 9.4e-35 120.1 0.2 1.4e-34 119.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX92419.1 - 3.4e-14 52.6 1.4 3.4e-14 52.6 1.4 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KFX92419.1 - 0.00055 19.7 0.1 0.0015 18.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 ketoacyl-synt PF00109.26 KFX92420.1 - 5.3e-78 262.1 0.0 1e-77 261.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFX92420.1 - 1.2e-65 221.6 8.7 1.2e-65 221.6 5.1 2.7 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFX92420.1 - 4.2e-39 134.9 0.0 9.4e-39 133.8 0.0 1.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX92420.1 - 1.2e-33 115.6 0.5 3e-33 114.3 0.5 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFX92420.1 - 3.7e-20 72.4 0.0 6.3e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KFX92420.1 - 6e-17 62.5 0.0 1.9e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain FAD_binding_3 PF01494.19 KFX92420.1 - 1.3e-15 57.5 1.2 1.7e-14 53.8 1.2 2.2 1 1 0 1 1 1 1 FAD binding domain PP-binding PF00550.25 KFX92420.1 - 1.8e-15 57.0 1.2 7.4e-15 55.1 1.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFX92420.1 - 6.2e-08 33.1 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KFX92420.1 - 0.0001 23.0 5.1 0.00018 22.2 1.7 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KFX92420.1 - 0.00058 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_8 PF13450.6 KFX92420.1 - 0.0023 18.1 0.2 0.019 15.2 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KFX92420.1 - 0.13 11.3 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase ACP_syn_III PF08545.10 KFX92420.1 - 0.17 11.7 0.6 0.73 9.7 0.6 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.11 KFX92421.1 - 1.9e-18 67.4 0.1 2.6e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.16 KFX92422.1 - 7.9e-38 130.3 57.6 1.9e-37 129.0 52.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 KFX92422.1 - 0.057 13.5 0.1 0.23 11.6 0.1 2.0 1 0 0 1 1 1 0 P5-type ATPase cation transporter HypD PF01924.16 KFX92422.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF4407 PF14362.6 KFX92422.1 - 0.16 11.3 0.8 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1295 PF06966.12 KFX92423.1 - 1e-14 54.6 0.0 1.5e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KFX92423.1 - 6.7e-06 25.1 0.1 1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KFX92423.1 - 0.0001 22.6 0.4 0.0013 19.1 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KFX92423.1 - 0.00027 20.5 0.0 0.00053 19.6 0.0 1.5 1 1 0 1 1 1 1 NnrU protein Steroid_dh PF02544.16 KFX92423.1 - 0.00061 19.8 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KFX92423.1 - 0.0033 17.8 0.0 0.0091 16.4 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family IFT20 PF14931.6 KFX92430.1 - 0.14 12.4 6.1 0.1 12.8 3.9 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 3-dmu-9_3-mt PF06983.13 KFX92431.1 - 2.3e-44 150.7 0.2 3.1e-44 150.2 0.2 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 KFX92431.1 - 0.00076 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NmrA PF05368.13 KFX92432.1 - 1.3e-32 113.2 0.1 6.2e-32 111.0 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX92432.1 - 1.1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX92432.1 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX92432.1 - 0.0044 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFX92432.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.24 KFX92432.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF736 PF05284.12 KFX92432.1 - 0.13 12.2 0.0 4.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF736) DUF3425 PF11905.8 KFX92433.1 - 9.3e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) AMP-binding_C PF13193.6 KFX92457.1 - 5.1e-16 59.4 0.0 3.1e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cucumo_2B PF03263.13 KFX92467.1 - 0.15 12.6 0.7 1.5 9.3 0.0 2.2 1 1 0 2 2 2 0 Cucumovirus protein 2B Zip PF02535.22 KFX92473.1 - 4.6e-26 91.8 7.1 4.8e-26 91.8 7.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.20 KFX92474.1 - 2.7e-115 384.4 0.7 3.4e-115 384.1 0.7 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFX92474.1 - 5.4e-05 22.5 0.1 0.00011 21.6 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 KFX92475.1 - 9.3e-39 130.7 24.3 5.7e-07 30.1 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KFX92475.1 - 3.2e-11 42.9 0.3 6.9e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFX92475.1 - 5.1e-11 42.7 1.0 0.028 14.7 0.0 6.4 2 1 6 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX92475.1 - 1.6e-06 27.1 4.1 0.26 9.9 0.2 5.0 1 1 5 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 KFX92475.1 - 1.7e-05 24.6 0.6 3.7e-05 23.5 0.6 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFX92475.1 - 7.1e-05 22.3 0.0 0.0086 15.4 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 KFX92475.1 - 0.007 16.4 0.1 2.9 8.0 0.0 3.5 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 KFX92475.1 - 0.013 15.1 4.8 0.018 14.6 1.0 2.5 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 KFX92475.1 - 0.046 14.2 2.0 50 4.6 0.0 4.9 5 1 1 6 6 6 0 PQQ-like domain PALB2_WD40 PF16756.5 KFX92475.1 - 0.085 11.8 3.2 4.8 6.0 0.0 3.3 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DTHCT PF08070.11 KFX92479.1 - 0.13 13.1 0.6 0.36 11.6 0.1 1.8 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF4588 PF15251.6 KFX92480.1 - 0.052 13.3 1.6 0.09 12.5 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DZR PF12773.7 KFX92480.1 - 2.7 8.1 35.6 1.7 8.7 16.0 4.3 2 1 2 4 4 4 0 Double zinc ribbon GCD14 PF08704.10 KFX92485.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RRM_1 PF00076.22 KFX92486.1 - 9.9e-44 147.0 0.0 7.7e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX92486.1 - 1.4e-05 25.0 0.1 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFX92486.1 - 6.2e-05 23.0 0.0 0.0012 18.8 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KFX92486.1 - 0.00017 21.4 0.0 0.059 13.2 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFX92486.1 - 0.0012 18.9 0.2 0.052 13.7 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KFX92486.1 - 0.018 14.7 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_4 PF01565.23 KFX92489.1 - 4.7e-13 49.1 0.4 9.5e-13 48.1 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX92489.1 - 2.8e-09 36.9 0.1 5.3e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like 2OG-FeII_Oxy PF03171.20 KFX92490.1 - 4.4e-11 43.2 0.0 1e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFX92490.1 - 0.0018 19.0 0.0 0.0033 18.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Haem_oxygenas_2 PF14518.6 KFX92491.1 - 1.8e-37 128.8 0.2 3.3e-37 128.0 0.2 1.4 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF553 PF04473.12 KFX92491.1 - 0.13 11.8 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 Transglutaminase-like domain Acetyltransf_1 PF00583.25 KFX92492.1 - 4.4e-09 36.6 0.0 7.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX92492.1 - 2.2e-06 28.0 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX92492.1 - 1.8e-05 24.7 0.0 4.6e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFX92492.1 - 0.0048 17.0 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX92492.1 - 0.0051 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFX92492.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Trp_DMAT PF11991.8 KFX92493.1 - 2.3e-74 251.0 0.0 2.9e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Vps16_N PF04841.13 KFX92493.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region AMP-binding PF00501.28 KFX92494.1 - 4e-46 157.5 0.0 5.5e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX92494.1 - 7e-05 23.7 0.0 0.0012 19.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Cupin_2 PF07883.11 KFX92495.1 - 1e-05 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX92495.1 - 0.024 14.2 0.3 0.035 13.7 0.3 1.3 1 1 0 1 1 1 0 Cupin COesterase PF00135.28 KFX92496.1 - 6.2e-69 233.2 0.0 2.7e-54 184.9 0.1 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX92496.1 - 0.099 12.5 0.2 0.34 10.7 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.15 KFX92497.1 - 3.3e-28 98.1 2.1 1.6e-27 95.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX92497.1 - 8.1e-27 94.3 0.0 6.3e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX92497.1 - 4.9e-23 81.4 7.5 1.5e-19 70.1 1.3 3.7 3 2 0 3 3 3 2 Multicopper oxidase PhzC-PhzF PF02567.16 KFX92498.1 - 9.3e-16 58.1 0.0 1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cyclin PF08613.11 KFX92499.1 - 2e-13 51.0 0.0 3.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFX92499.1 - 0.0025 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DHHC PF01529.20 KFX92500.1 - 2.4e-38 131.3 7.7 3.7e-38 130.6 7.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase His_Phos_1 PF00300.22 KFX92500.1 - 0.06 13.0 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF4064 PF13273.6 KFX92500.1 - 0.087 13.1 0.0 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Rab5ip PF07019.12 KFX92500.1 - 9.2 6.9 9.3 11 6.7 4.8 2.4 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-C2H2_6 PF13912.6 KFX92501.1 - 2.5e-05 24.1 3.1 0.0034 17.3 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFX92501.1 - 0.00011 22.8 3.7 0.043 14.4 0.7 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KFX92501.1 - 0.0015 18.8 1.6 0.0027 18.0 1.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KFX92501.1 - 0.0053 17.1 4.6 0.75 10.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type CGGC PF08821.11 KFX92501.1 - 0.031 14.4 0.3 0.059 13.6 0.3 1.5 1 0 0 1 1 1 0 CGGC domain zf-C2H2_9 PF16293.5 KFX92501.1 - 0.038 13.8 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 KFX92501.1 - 0.048 14.5 1.2 6.8 7.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KFX92501.1 - 0.23 11.8 3.0 3.5 8.0 3.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ROK PF00480.20 KFX92501.1 - 0.25 10.8 0.8 0.69 9.3 0.1 1.8 1 1 1 2 2 2 0 ROK family TIP120 PF08623.10 KFX92502.1 - 2.5e-70 235.6 2.2 2.1e-68 229.3 0.1 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KFX92502.1 - 5.1e-10 38.7 14.6 1.1 9.7 0.0 10.8 11 0 0 11 11 10 1 HEAT repeat HEAT_2 PF13646.6 KFX92502.1 - 4e-08 33.5 16.9 0.24 11.8 0.1 8.6 8 0 0 8 8 8 3 HEAT repeats RTP1_C1 PF10363.9 KFX92502.1 - 5.7e-08 32.9 11.0 0.026 14.7 0.0 6.7 7 1 0 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KFX92502.1 - 6.6e-06 26.2 9.9 0.19 11.8 0.1 4.6 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 KFX92502.1 - 7e-05 21.5 0.5 0.097 11.2 0.1 4.3 3 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 KFX92502.1 - 8.3e-05 21.3 12.0 0.079 11.5 1.2 5.5 5 1 1 6 6 6 1 Adaptin N terminal region HEAT_EZ PF13513.6 KFX92502.1 - 0.00016 22.1 24.2 18 5.9 0.8 11.4 11 2 1 12 12 12 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFX92502.1 - 0.00028 21.4 1.0 4 8.1 0.0 6.4 6 3 2 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFX92502.1 - 0.021 14.4 0.5 0.96 9.0 0.0 3.8 4 1 1 5 5 5 0 CLASP N terminal Cnd3 PF12719.7 KFX92502.1 - 0.032 13.4 0.6 9.4 5.3 0.0 4.2 5 1 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3510 PF12022.8 KFX92502.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) VHS PF00790.19 KFX92502.1 - 0.085 12.7 0.0 23 4.8 0.0 4.2 4 0 0 4 4 4 0 VHS domain DUF4042 PF13251.6 KFX92502.1 - 0.14 11.8 7.4 18 5.0 0.0 6.2 7 1 1 8 8 8 0 Domain of unknown function (DUF4042) Importin_rep_5 PF18816.1 KFX92502.1 - 0.17 12.2 0.4 8.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Importin repeat FAM60A PF15396.6 KFX92503.1 - 0.3 11.1 14.9 0.48 10.4 14.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 KFX92503.1 - 0.3 9.2 13.3 0.32 9.1 13.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 KFX92503.1 - 0.71 8.6 12.8 1 8.1 12.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 KFX92503.1 - 0.9 9.8 10.2 1.1 9.5 10.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 KFX92503.1 - 1.4 8.9 8.4 2.2 8.3 8.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.6 KFX92503.1 - 4.8 7.3 17.1 7.8 6.6 17.1 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 LAP1C PF05609.12 KFX92503.1 - 9.6 5.2 24.5 13 4.7 24.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PLAC8 PF04749.17 KFX92504.1 - 2.1e-14 54.3 7.4 4.2e-14 53.3 7.4 1.5 1 0 0 1 1 1 1 PLAC8 family Ras PF00071.22 KFX92505.1 - 4.7e-31 107.6 0.1 6.3e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX92505.1 - 1.3e-23 83.5 0.1 2.3e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX92505.1 - 1.7e-06 27.6 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX92505.1 - 9.6e-05 21.8 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KFX92505.1 - 0.0013 17.6 0.1 0.24 10.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) GCV_H PF01597.19 KFX92506.1 - 2.2e-32 111.5 0.3 2.6e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.20 KFX92507.1 - 9.4e-76 253.9 0.0 1.2e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFX92507.1 - 7e-20 71.2 0.4 1.5e-19 70.2 0.4 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Methyltransf_23 PF13489.6 KFX92508.1 - 6e-23 81.5 0.0 8.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX92508.1 - 9.4e-11 42.3 0.0 2.6e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92508.1 - 6.4e-10 39.6 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92508.1 - 5.1e-07 29.6 0.0 1.6e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX92508.1 - 5.1e-06 27.2 0.0 6.5e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX92508.1 - 0.0041 16.6 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KFX92508.1 - 0.023 14.8 0.0 0.06 13.4 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase JUPITER PF17054.5 KFX92508.1 - 0.043 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter PrmA PF06325.13 KFX92508.1 - 0.066 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KFX92508.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KFX92508.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain DUF1996 PF09362.10 KFX92509.1 - 8.3e-78 261.6 3.2 1e-77 261.3 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 KFX92509.1 - 7.7e-13 48.2 10.8 7.7e-13 48.2 10.8 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX92509.1 - 0.0011 19.1 2.1 0.0031 17.7 2.1 1.8 1 0 0 1 1 1 1 Toxin 7 WD40 PF00400.32 KFX92513.1 - 6.1e-10 39.5 1.3 0.079 13.9 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX92513.1 - 3.6e-08 33.6 0.1 0.00028 21.1 0.0 4.0 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Prp19 PF08606.11 KFX92513.1 - 0.00023 21.1 1.0 0.00053 19.9 1.0 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like Coatomer_WDAD PF04053.14 KFX92513.1 - 0.0031 16.6 0.0 0.027 13.5 0.0 2.2 1 1 2 3 3 3 2 Coatomer WD associated region VID27 PF08553.10 KFX92513.1 - 0.054 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain V_ATPase_I_N PF18670.1 KFX92513.1 - 0.22 12.0 2.4 0.4 11.1 0.7 2.2 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain Chs7 PF12271.8 KFX92514.1 - 3.7e-127 423.6 15.3 4.2e-127 423.4 15.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KFX92514.1 - 5.9 7.2 13.0 0.51 10.6 2.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) NTP_transferase PF00483.23 KFX92517.1 - 3.9e-31 108.5 0.0 5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KFX92517.1 - 4.8e-10 38.8 6.4 1.1e-06 28.1 0.1 3.7 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFX92517.1 - 3e-07 30.9 0.0 4.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFX92517.1 - 0.0031 17.2 0.7 0.087 12.6 0.0 3.3 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFX92517.1 - 0.0098 14.9 0.2 0.75 8.7 0.1 2.2 2 0 0 2 2 2 2 L-fucokinase IspD PF01128.19 KFX92517.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dynamin_N PF00350.23 KFX92518.1 - 2.4e-20 73.3 0.0 2.1e-19 70.2 0.0 2.5 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX92518.1 - 3.1e-18 66.0 1.3 9.5e-13 48.0 0.1 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KFX92518.1 - 1.8e-06 28.0 0.4 7.6e-06 26.0 0.4 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_16 PF13191.6 KFX92518.1 - 3.9e-05 24.1 0.9 0.34 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFX92518.1 - 0.00082 19.4 0.0 0.02 15.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AbiTii PF18864.1 KFX92518.1 - 0.087 13.0 0.1 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 AbiTii TraQ PF09679.10 KFX92519.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF5556 PF17711.1 KFX92519.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5556) Tti2 PF10521.9 KFX92519.1 - 7.5 6.0 6.1 0.85 9.1 0.1 2.0 2 0 0 2 2 2 0 Tti2 family APH PF01636.23 KFX92520.1 - 4.3e-10 39.9 0.0 5.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX92520.1 - 1.7e-06 27.6 0.1 2.6e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFX92520.1 - 5.9e-06 26.0 0.1 1.4e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KFX92520.1 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 KFX92520.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF16 PF01519.16 KFX92521.1 - 0.35 11.4 3.8 1.1 9.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 ASCH PF04266.14 KFX92522.1 - 0.05 14.2 0.0 0.27 11.8 0.0 2.0 1 1 0 1 1 1 0 ASCH domain HIT PF01230.23 KFX92523.1 - 2.6e-19 69.7 0.1 5.2e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KFX92523.1 - 4.1e-05 24.0 0.0 7.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFX92523.1 - 0.0026 17.6 0.0 0.0074 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 DUF2203 PF09969.9 KFX92525.1 - 0.00092 19.9 4.4 0.0013 19.5 4.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.6 KFX92525.1 - 0.03 13.0 0.7 0.036 12.7 0.7 1.0 1 0 0 1 1 1 0 AAA domain DinB PF05163.12 KFX92525.1 - 0.078 12.9 0.5 0.078 12.9 0.5 2.0 1 1 0 2 2 2 0 DinB family PFK PF00365.20 KFX92525.1 - 0.2 11.0 0.1 0.25 10.6 0.1 1.1 1 0 0 1 1 1 0 Phosphofructokinase ATG16 PF08614.11 KFX92525.1 - 0.92 9.7 12.0 1.1 9.4 8.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KFX92525.1 - 3 6.3 5.9 4.8 5.6 5.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family RNA_pol_Rpb4 PF03874.16 KFX92536.1 - 1.6e-26 93.0 2.1 2e-26 92.7 2.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1978 PF09321.10 KFX92536.1 - 0.02 14.2 0.2 0.032 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Cut8 PF08559.10 KFX92536.1 - 0.065 12.8 0.1 0.087 12.4 0.1 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein DUF789 PF05623.12 KFX92536.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Sybindin PF04099.12 KFX92537.1 - 3.8e-51 172.8 0.0 4.9e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFX92537.1 - 1e-09 38.6 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 KFX92538.1 - 3.2e-27 95.3 0.3 7.5e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFX92538.1 - 7.3e-11 42.6 0.4 1e-10 42.2 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KFX92538.1 - 5.4e-07 29.6 0.1 8.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KFX92538.1 - 0.009 15.9 1.1 0.022 14.7 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF871 PF05913.11 KFX92538.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) LRR_6 PF13516.6 KFX92544.1 - 2.4e-07 30.2 7.7 0.07 13.2 0.1 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KFX92544.1 - 5.8e-06 26.6 11.5 2.6 8.6 2.3 6.1 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFX92544.1 - 0.021 15.3 2.8 11 7.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat NOA36 PF06524.12 KFX92544.1 - 0.03 13.7 4.4 0.043 13.1 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_8 PF13855.6 KFX92544.1 - 1.1 9.1 11.9 1.6 8.6 0.0 4.6 4 1 0 4 4 4 0 Leucine rich repeat RRN3 PF05327.11 KFX92544.1 - 2 6.9 12.5 2.9 6.3 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 COX17 PF05051.13 KFX92545.1 - 6.4e-21 74.4 6.0 7.7e-21 74.2 6.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Sec10 PF07393.11 KFX92546.1 - 6.7e-223 742.1 3.7 9.5e-223 741.6 3.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Ku_PK_bind PF08785.11 KFX92546.1 - 0.0054 16.9 0.6 0.24 11.5 0.0 2.8 2 0 0 2 2 2 1 Ku C terminal domain like GAS PF13851.6 KFX92546.1 - 0.031 13.6 1.0 0.1 12.0 1.0 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Arg_decarbox_C PF17944.1 KFX92546.1 - 0.034 14.7 1.2 7.4 7.2 0.2 4.4 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension Baculo_PEP_C PF04513.12 KFX92546.1 - 0.15 12.1 3.5 0.45 10.5 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prenyltransf PF01255.19 KFX92547.1 - 0.0065 16.0 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase IBR PF01485.21 KFX92548.1 - 2.2e-13 50.2 28.2 1.9e-08 34.4 5.0 2.6 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain MFS_1 PF07690.16 KFX92549.1 - 3.1e-37 128.3 58.7 5.2e-36 124.3 54.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92549.1 - 1.5e-11 43.8 14.4 1.5e-11 43.8 14.4 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter UL42 PF17638.2 KFX92549.1 - 0.12 12.4 0.7 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 HCMV UL42 TMEM40 PF15817.5 KFX92549.1 - 0.34 10.7 3.5 1.1 9.1 3.5 1.9 1 0 0 1 1 1 0 Transmembrane protein 40 family Met_10 PF02475.16 KFX92550.1 - 1.9e-64 217.1 0.0 2.8e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Glyco_transf_34 PF05637.12 KFX92550.1 - 2e-61 207.8 0.2 2.9e-61 207.2 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family HATPase_c PF02518.26 KFX92551.1 - 1e-30 106.5 0.0 4.4e-30 104.5 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFX92551.1 - 2.7e-21 75.8 0.1 1.1e-20 73.9 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFX92551.1 - 4.7e-20 71.4 0.7 3.6e-19 68.6 0.2 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KFX92551.1 - 1.1e-15 58.5 0.1 6.7e-15 55.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 KFX92551.1 - 7.5e-11 42.5 0.0 2.7e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KFX92551.1 - 4.4e-07 29.5 0.0 9.9e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KFX92551.1 - 0.00018 22.1 0.0 0.00053 20.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 KFX92551.1 - 0.0044 16.9 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain HATPase_c_3 PF13589.6 KFX92551.1 - 0.0099 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 KFX92551.1 - 0.09 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase GAF_3 PF13492.6 KFX92551.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain MeaB PF03308.16 KFX92551.1 - 0.12 11.4 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PTS_EIIB PF00367.20 KFX92551.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 phosphotransferase system, EIIB TPT PF03151.16 KFX92556.1 - 5.2e-19 68.7 24.5 2.9e-16 59.7 13.8 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KFX92556.1 - 0.049 12.8 15.7 0.11 11.7 15.3 1.7 1 1 0 1 1 1 0 UAA transporter family DUF2061 PF09834.9 KFX92556.1 - 0.063 13.8 0.6 0.063 13.8 0.6 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) PDR_CDR PF06422.12 KFX92556.1 - 0.076 12.9 0.2 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 CDR ABC transporter EamA PF00892.20 KFX92556.1 - 1 9.5 31.9 0.46 10.6 2.0 3.9 3 1 0 4 4 4 0 EamA-like transporter family NAD_binding_8 PF13450.6 KFX92557.1 - 3.2e-08 33.7 0.0 9.2e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFX92557.1 - 3.6e-08 33.1 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX92557.1 - 0.0025 17.1 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX92557.1 - 0.0043 16.3 0.0 0.022 14.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX92557.1 - 0.009 15.3 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KFX92557.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KFX92557.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KFX92557.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KFX92557.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX92557.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein LysM PF01476.20 KFX92563.1 - 5e-16 58.5 6.9 2.4e-05 24.3 0.0 6.5 7 0 0 7 7 7 3 LysM domain SpoIISA_toxin PF14171.6 KFX92563.1 - 0.3 10.7 1.1 0.5 10.0 1.1 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Glyco_hydro_18 PF00704.28 KFX92564.1 - 9.3e-74 249.0 1.3 1.8e-73 248.0 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX92564.1 - 4.1e-13 49.6 12.2 4.1e-13 49.6 12.2 4.9 5 0 0 5 5 5 2 Chitin recognition protein BUD22 PF09073.10 KFX92565.1 - 0.045 13.1 24.3 0.03 13.7 21.0 2.1 2 0 0 2 2 2 0 BUD22 F-box-like PF12937.7 KFX92565.1 - 0.1 12.5 0.0 0.44 10.5 0.0 2.1 1 1 0 1 1 1 0 F-box-like PI3K_1B_p101 PF10486.9 KFX92565.1 - 0.14 9.9 9.0 0.2 9.4 9.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ALS2CR11 PF15729.5 KFX92565.1 - 0.23 10.6 7.1 0.38 9.8 7.1 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 MPP6 PF10175.9 KFX92565.1 - 0.88 10.1 11.6 2.3 8.7 11.6 1.7 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF4763 PF15960.5 KFX92565.1 - 1.9 7.7 9.0 4.1 6.6 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Nop14 PF04147.12 KFX92565.1 - 2.4 6.2 16.5 3.8 5.6 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFX92565.1 - 3.7 5.7 10.4 6.7 4.9 10.4 1.4 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KFX92565.1 - 4.4 5.8 21.0 7 5.1 21.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PTPRCAP PF15713.5 KFX92565.1 - 8.7 6.6 19.6 20 5.5 19.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated WD40 PF00400.32 KFX92566.1 - 1.5e-14 54.1 13.8 0.001 19.9 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX92566.1 - 6e-09 36.1 0.0 0.001 19.3 0.0 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFX92566.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 KFX92566.1 - 0.11 11.4 0.0 0.76 8.7 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX92566.1 - 0.15 10.7 0.1 0.69 8.5 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 STE2 PF02116.15 KFX92570.1 - 5.1e-96 321.3 21.5 5.9e-96 321.1 21.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Vps23_core PF09454.10 KFX92572.1 - 3.5e-21 74.9 0.0 8.4e-21 73.7 0.0 1.6 2 0 0 2 2 2 1 Vps23 core domain Sugar_tr PF00083.24 KFX92574.1 - 1.2e-58 199.1 15.9 6.4e-49 167.0 6.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KFX92574.1 - 3.2e-06 26.0 15.7 0.00015 20.5 3.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 KFX92574.1 - 4.3e-05 22.6 37.1 8.3e-05 21.7 29.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CTNNBL PF08216.11 KFX92575.1 - 2.1e-40 137.1 0.9 4.1e-40 136.1 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear SpecificRecomb PF10136.9 KFX92575.1 - 0.0031 15.9 0.1 0.0047 15.3 0.1 1.3 1 0 0 1 1 1 1 Site-specific recombinase Arm PF00514.23 KFX92575.1 - 0.0087 16.1 0.0 1.1 9.4 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 KFX92575.1 - 0.026 13.9 0.6 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5578) Mo25 PF08569.11 KFX92575.1 - 0.074 12.4 0.8 0.099 12.0 0.1 1.6 2 0 0 2 2 2 0 Mo25-like TPR_2 PF07719.17 KFX92576.1 - 5e-07 29.3 0.0 0.096 12.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 KFX92576.1 - 1.9e-06 27.7 0.1 3.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 KFX92576.1 - 2.4e-05 24.5 0.3 0.12 12.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 KFX92576.1 - 0.00013 21.8 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KFX92576.1 - 0.00076 19.2 0.0 0.88 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 KFX92576.1 - 0.0084 16.5 14.1 0.34 11.4 1.9 6.2 6 2 1 7 7 7 1 Leucine Rich repeats (2 copies) TPR_11 PF13414.6 KFX92576.1 - 0.032 13.9 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 TPR repeat LRR_8 PF13855.6 KFX92576.1 - 0.11 12.3 5.9 1.1 9.1 2.0 4.2 5 1 0 5 5 5 0 Leucine rich repeat TPR_8 PF13181.6 KFX92576.1 - 0.12 12.7 0.0 57 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1996 PF09362.10 KFX92577.1 - 1.9e-90 302.9 1.6 2.8e-90 302.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MS_channel PF00924.18 KFX92580.1 - 8.5e-15 54.9 0.0 9e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel Membr_traf_MHD PF10540.9 KFX92581.1 - 1.3e-17 64.4 4.6 2.2e-15 57.1 0.7 3.2 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KFX92581.1 - 7.3e-16 58.3 0.2 6e-15 55.4 0.0 2.4 3 0 0 3 3 3 1 C2 domain DUF810 PF05664.11 KFX92581.1 - 7.9e-10 37.9 0.7 1.6e-09 36.9 0.7 1.5 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) TipAS PF07739.13 KFX92581.1 - 0.27 11.8 2.8 1.6 9.3 0.0 3.1 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Ins_P5_2-kin PF06090.12 KFX92584.1 - 1.1e-29 104.0 0.0 1.2e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MFS_1 PF07690.16 KFX92591.1 - 2.5e-20 72.7 53.0 2.3e-17 63.0 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX92591.1 - 3.2e-06 26.0 6.4 3.2e-06 26.0 6.4 3.1 2 1 2 4 4 4 3 MFS/sugar transport protein Fungal_trans PF04082.18 KFX92593.1 - 1.4e-33 116.0 0.2 2.5e-33 115.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92593.1 - 8.8e-05 22.5 13.6 0.00016 21.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 KFX92594.1 - 2.7e-42 144.5 1.6 2e-20 73.7 0.0 4.0 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 KFX92594.1 - 1.1e-16 61.5 6.7 0.00021 21.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX92594.1 - 1.9e-08 34.0 1.1 0.025 14.0 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KFX92594.1 - 2.1e-07 30.9 2.9 2.1e-07 30.9 2.9 1.9 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KFX92594.1 - 1e-06 28.8 0.1 0.031 14.4 0.0 3.7 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KFX92594.1 - 1.5e-06 27.9 0.5 0.002 17.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX92594.1 - 2.4e-06 27.4 0.4 0.054 13.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KFX92594.1 - 1.7e-05 25.1 0.2 0.33 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFX92594.1 - 5.8e-05 23.5 6.2 0.049 14.0 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KFX92594.1 - 6.4e-05 23.5 0.0 0.09 13.3 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX92594.1 - 0.0001 22.6 1.9 2.8 8.2 0.1 3.9 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KFX92594.1 - 0.00012 22.6 13.3 0.0064 17.0 1.5 3.3 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 KFX92594.1 - 0.00066 19.6 0.0 0.2 11.6 0.0 2.7 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 KFX92594.1 - 0.0016 18.6 3.3 0.13 12.4 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain Thymidylate_kin PF02223.17 KFX92594.1 - 0.0052 16.5 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase MobB PF03205.14 KFX92594.1 - 0.0067 16.3 0.1 1.1 9.2 0.2 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 KFX92594.1 - 0.0073 16.2 0.0 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KFX92594.1 - 0.014 15.4 0.0 5.8 6.8 0.0 3.1 4 0 0 4 4 2 0 NTPase Zeta_toxin PF06414.12 KFX92594.1 - 0.016 14.5 0.0 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 KFX92594.1 - 0.028 13.9 0.1 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 KFX92594.1 - 0.04 13.5 0.3 2.7 7.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KFX92594.1 - 0.041 13.2 0.1 0.68 9.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KFX92594.1 - 0.043 14.0 0.2 9.2 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KFX92594.1 - 0.044 12.8 1.0 0.66 8.9 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KFX92594.1 - 0.053 12.7 4.1 7.7 5.6 0.0 3.9 4 0 0 4 4 4 0 NB-ARC domain SRP54 PF00448.22 KFX92594.1 - 0.059 13.0 0.2 2.8 7.5 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX92594.1 - 0.069 13.2 0.4 4.4 7.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFX92594.1 - 0.078 12.1 0.1 0.31 10.1 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 KFX92594.1 - 0.08 12.6 8.6 0.095 12.4 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain COG2 PF06148.11 KFX92594.1 - 0.086 12.9 0.1 0.73 9.9 0.0 2.5 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RNA_helicase PF00910.22 KFX92594.1 - 0.14 12.5 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KFX92594.1 - 0.16 12.0 1.9 20 5.2 0.1 3.2 3 1 0 3 3 2 0 Dynamin family Castor_Poll_mid PF06241.12 KFX92594.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel SNF2_N PF00176.23 KFX92595.1 - 9.1e-22 77.2 0.0 1.3e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KFX92595.1 - 4.5e-16 59.1 0.0 1.3e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KFX92595.1 - 3.8e-06 27.2 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KFX92595.1 - 0.0028 17.6 6.8 0.0028 17.6 6.8 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX92595.1 - 1.6 8.9 8.2 2.6 8.1 1.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Pyr_redox_2 PF07992.14 KFX92596.1 - 1.2e-17 64.1 0.0 1.2e-16 60.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX92596.1 - 0.00018 20.4 0.0 0.022 13.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KFX92596.1 - 0.0003 20.2 0.2 0.61 9.3 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX92596.1 - 0.00099 18.3 0.8 0.95 8.5 0.0 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFX92596.1 - 0.012 15.6 0.4 0.74 9.8 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KFX92596.1 - 0.15 11.6 2.9 9 5.8 1.1 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase Rick_17kDa_Anti PF05433.15 KFX92598.1 - 0.0062 16.4 3.9 0.01 15.7 3.9 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain SKG6 PF08693.10 KFX92598.1 - 0.064 12.7 3.5 0.11 11.9 3.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4149 PF13664.6 KFX92598.1 - 0.097 13.0 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) EphA2_TM PF14575.6 KFX92598.1 - 0.1 13.5 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF456 PF04306.13 KFX92598.1 - 0.92 9.8 7.4 1.4 9.2 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Recep_L_domain PF01030.24 KFX92599.1 - 0.00071 19.7 0.7 0.12 12.5 0.0 3.1 2 1 1 3 3 3 1 Receptor L domain SKG6 PF08693.10 KFX92599.1 - 0.0047 16.3 1.9 0.0085 15.5 1.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TPR_12 PF13424.6 KFX92601.1 - 3.8e-49 164.9 16.6 9.6e-14 51.4 2.6 7.5 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFX92601.1 - 1.1e-37 126.8 28.5 7.5e-06 25.6 0.3 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat NB-ARC PF00931.22 KFX92601.1 - 1.7e-17 63.5 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KFX92601.1 - 1.3e-16 59.9 19.6 0.014 16.2 0.2 9.8 7 2 4 11 11 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFX92601.1 - 4.2e-16 59.2 10.5 0.00015 22.2 1.1 7.3 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFX92601.1 - 3.5e-11 42.3 27.1 0.0091 16.0 1.2 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX92601.1 - 2.5e-10 40.8 19.5 0.00063 20.3 2.3 8.1 5 3 2 7 7 6 2 Tetratricopeptide repeat ADH_N PF08240.12 KFX92601.1 - 4e-09 36.3 0.1 1.3e-08 34.7 0.1 1.8 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain TPR_8 PF13181.6 KFX92601.1 - 7.1e-09 35.2 17.7 0.072 13.3 0.1 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX92601.1 - 1.3e-08 34.6 6.8 0.00062 19.2 0.6 3.6 1 1 1 3 3 3 3 MalT-like TPR region ADH_zinc_N PF00107.26 KFX92601.1 - 6.6e-08 32.6 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SesA PF17107.5 KFX92601.1 - 2e-07 31.2 0.0 8.1e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_1 PF00515.28 KFX92601.1 - 1.5e-06 27.8 13.7 0.084 12.7 0.7 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX92601.1 - 2.5e-06 27.1 14.2 1.6 8.9 0.3 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFX92601.1 - 7.1e-06 26.2 13.9 1.2 10.0 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX92601.1 - 2.4e-05 24.5 3.4 0.078 13.2 0.6 5.3 4 1 3 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 KFX92601.1 - 0.00055 20.3 0.1 0.0026 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain ADH_zinc_N_2 PF13602.6 KFX92601.1 - 0.00077 20.5 0.1 0.0023 19.0 0.1 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPR_5 PF12688.7 KFX92601.1 - 0.0017 18.6 2.0 2.6 8.3 0.3 3.4 1 1 0 2 2 2 2 Tetratrico peptide repeat TPR_17 PF13431.6 KFX92601.1 - 0.0022 18.3 1.0 0.052 14.0 0.3 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat NACHT PF05729.12 KFX92601.1 - 0.0041 17.1 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_20 PF14561.6 KFX92601.1 - 0.0059 16.9 7.2 0.5 10.7 0.7 5.2 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX92601.1 - 0.0081 15.8 2.4 17 5.2 0.0 3.8 3 0 0 3 3 3 0 TPR repeat TPR_21 PF09976.9 KFX92601.1 - 0.02 14.6 2.2 0.049 13.3 0.8 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain Zeta_toxin PF06414.12 KFX92601.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TPR_6 PF13174.6 KFX92601.1 - 0.36 11.6 20.7 1.5 9.6 0.6 7.0 8 0 0 8 8 5 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KFX92602.1 - 3.4e-29 101.7 0.5 7e-29 100.7 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92602.1 - 1.1e-07 31.9 15.8 2.7e-07 30.6 15.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 KFX92603.1 - 6.9e-16 58.2 0.0 2.6e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFX92603.1 - 1.2e-09 38.0 0.0 1.3e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFX92603.1 - 5.8e-08 32.7 0.0 5.2e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX92603.1 - 2.6e-06 26.9 0.2 0.0001 21.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX92603.1 - 2.4e-05 23.6 0.2 0.00084 18.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFX92603.1 - 0.0036 16.0 0.1 0.69 8.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KFX92603.1 - 0.0058 16.6 0.2 0.1 12.6 0.0 2.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFX92603.1 - 0.01 16.4 0.3 4.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX92603.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KFX92603.1 - 0.2 10.7 0.2 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DLH PF01738.18 KFX92604.1 - 1.5e-30 106.4 0.0 1.7e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2497 PF10691.9 KFX92604.1 - 0.086 13.3 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) FMO-like PF00743.19 KFX92605.1 - 2.7e-49 168.0 0.0 3.1e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX92605.1 - 1.2e-19 70.7 0.1 1.5e-19 70.4 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX92605.1 - 3.1e-10 39.8 0.0 3.8e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX92605.1 - 2.6e-09 36.7 0.1 4.8e-09 35.8 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFX92605.1 - 0.00032 20.4 0.6 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFX92605.1 - 0.00074 18.9 0.3 0.15 11.4 0.3 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFX92605.1 - 0.0027 17.3 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 KFX92605.1 - 0.0092 15.6 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KFX92605.1 - 0.012 15.8 1.0 0.058 13.6 0.5 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KFX92605.1 - 0.013 16.0 0.0 5.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KFX92605.1 - 0.02 15.5 2.7 0.78 10.3 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX92605.1 - 0.087 13.1 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_M17_N PF02789.17 KFX92605.1 - 0.16 11.8 0.5 17 5.3 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain LMWPc PF01451.21 KFX92610.1 - 1.8e-13 51.1 0.0 2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ABATE PF07336.11 KFX92610.1 - 0.0027 18.4 0.3 0.0046 17.6 0.3 1.4 1 0 0 1 1 1 1 Putative stress-induced transcription regulator Polysacc_deac_1 PF01522.21 KFX92610.1 - 0.0061 16.5 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF1488 PF07369.11 KFX92610.1 - 0.019 14.9 0.2 0.031 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) PTE PF02126.18 KFX92610.1 - 0.15 11.5 0.2 0.22 10.9 0.1 1.3 2 0 0 2 2 2 0 Phosphotriesterase family CHAP PF05257.16 KFX92611.1 - 4.8e-13 49.5 4.8 4.8e-13 49.5 4.8 2.0 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.11 KFX92611.1 - 0.00011 22.5 1.3 0.00018 21.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Porin_OmpG_1_2 PF16946.5 KFX92611.1 - 0.024 13.9 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 OMPG-porin 1 family Phage_lysozyme PF00959.19 KFX92612.1 - 2.4e-12 47.3 0.0 3.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.11 KFX92612.1 - 7.1e-06 26.2 0.2 0.00011 22.4 0.2 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain ABC1 PF03109.16 KFX92616.1 - 4.4e-31 107.5 0.0 7.4e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family SpecificRecomb PF10136.9 KFX92616.1 - 0.068 11.5 0.0 0.095 11.0 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase Ank_2 PF12796.7 KFX92629.1 - 6.4e-79 260.6 4.1 1.5e-15 57.5 0.0 6.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX92629.1 - 7.4e-54 173.4 2.4 3.1e-05 24.0 0.0 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 KFX92629.1 - 8.9e-50 166.5 4.7 3e-08 34.0 0.1 7.7 4 3 2 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFX92629.1 - 4.1e-43 144.0 11.9 6.5e-06 26.4 0.0 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 KFX92629.1 - 2.3e-41 139.3 13.6 9.4e-09 35.4 0.1 10.0 2 2 8 10 10 10 9 Ankyrin repeats (many copies) F-box-like PF12937.7 KFX92629.1 - 2.3e-05 24.2 0.0 0.00011 22.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like VWA_3_C PF18571.1 KFX92629.1 - 0.014 15.2 0.1 11 6.0 0.0 3.8 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain RVP PF00077.20 KFX92629.1 - 0.027 14.8 0.7 12 6.3 0.0 3.7 2 1 2 4 4 4 0 Retroviral aspartyl protease Ank_2 PF12796.7 KFX92630.1 - 2e-18 66.7 0.0 1.6e-10 41.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX92630.1 - 7.2e-16 58.1 0.1 6e-09 36.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX92630.1 - 4.7e-15 55.7 0.1 2.2e-05 24.9 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92630.1 - 5.6e-15 53.9 0.0 0.00075 19.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KFX92630.1 - 3.2e-12 46.3 0.1 0.0016 18.8 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Putative_PNPOx PF01243.20 KFX92631.1 - 0.19 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1604 PF07713.13 KFX92639.1 - 6.7e-40 134.8 1.9 2.1e-39 133.2 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFX92639.1 - 7.4e-07 29.0 1.6 2.2e-06 27.4 1.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFX92639.1 - 0.48 10.6 6.0 0.15 12.2 1.0 2.9 2 1 1 3 3 3 0 G-patch domain Pkinase PF00069.25 KFX92640.1 - 7.6e-70 235.3 0.1 1.9e-69 234.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92640.1 - 1.3e-38 132.8 0.1 1.1e-37 129.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFX92640.1 - 9.6e-19 66.9 0.2 1.9e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KFX92640.1 - 0.00011 21.6 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFX92640.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX92640.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFX92640.1 - 0.0033 17.4 0.0 0.018 15.0 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 KFX92640.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KFX92640.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Rcd1 PF04078.13 KFX92641.1 - 2.8e-126 420.1 4.7 3.3e-126 419.9 4.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like 2H-phosphodiest PF08975.10 KFX92641.1 - 0.088 12.8 0.3 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) bZIP_1 PF00170.21 KFX92642.1 - 1.9e-05 24.7 0.8 5.1e-05 23.3 0.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFX92642.1 - 0.021 15.3 3.0 0.1 13.2 3.0 2.1 1 0 0 1 1 1 0 bZIP Maf transcription factor CSN8_PSD8_EIF3K PF10075.9 KFX92646.1 - 2.8e-17 63.0 0.0 3.7e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Poly_export PF02563.16 KFX92646.1 - 0.075 13.3 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein SAC3_GANP PF03399.16 KFX92646.1 - 0.15 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP family Cu_amine_oxid PF01179.20 KFX92647.1 - 2.4e-161 537.3 0.0 2.9e-161 537.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KFX92647.1 - 2.5e-10 40.4 0.0 6.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KFX92647.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Amidohydro_1 PF01979.20 KFX92648.1 - 1.5e-25 90.2 0.0 2e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX92648.1 - 2.6e-11 43.7 0.1 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KFX92649.1 - 2.9e-06 26.3 1.3 2.9e-06 26.3 1.3 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Peptidase_C32 PF05411.12 KFX92650.1 - 0.053 13.5 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase PhyH PF05721.13 KFX92651.1 - 1.9e-26 93.6 0.0 3.7e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_16 PF00722.21 KFX92652.1 - 2.9e-07 30.1 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TF_Otx PF03529.13 KFX92652.1 - 0.076 13.4 1.5 0.28 11.6 1.5 2.0 1 0 0 1 1 1 0 Otx1 transcription factor AA_permease_2 PF13520.6 KFX92653.1 - 7.2e-35 120.6 53.6 8.9e-35 120.3 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX92653.1 - 9.2e-16 57.5 44.4 1.3e-15 57.0 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pheromone PF08015.11 KFX92654.1 - 7.3 7.7 11.6 26 5.9 11.6 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone MFS_1 PF07690.16 KFX92655.1 - 8.5e-30 103.9 33.6 1e-29 103.6 32.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX92655.1 - 0.00049 19.5 3.7 0.00049 19.5 3.7 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PARP PF00644.20 KFX92656.1 - 3.6e-57 193.1 1.8 2.5e-50 170.8 0.0 3.1 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFX92656.1 - 8.2e-42 142.5 0.1 1.4e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KFX92656.1 - 2e-15 56.6 15.4 1.4e-13 50.7 1.0 3.1 3 0 0 3 3 3 2 WGR domain BRCT PF00533.26 KFX92656.1 - 1.7e-09 37.9 0.0 3.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFX92656.1 - 1.2e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFX92656.1 - 0.00013 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFX92656.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF936 PF06075.12 KFX92656.1 - 0.041 12.8 8.1 0.062 12.2 8.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) LIG3_BRCT PF16759.5 KFX92656.1 - 0.19 12.0 0.3 0.49 10.7 0.3 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain FAM104 PF15434.6 KFX92656.1 - 0.37 11.4 3.3 0.18 12.4 0.6 1.8 2 0 0 2 2 2 0 Family 104 RNA_pol_Rpc4 PF05132.14 KFX92656.1 - 2.6 8.4 6.6 0.44 11.0 1.7 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Metallophos PF00149.28 KFX92657.1 - 1.3e-26 94.3 0.6 4.5e-26 92.6 0.6 2.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KFX92657.1 - 2.4e-15 56.9 0.4 2.4e-15 56.9 0.4 3.4 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KFX92657.1 - 8.5e-14 52.2 0.1 5e-13 49.7 0.1 2.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C p450 PF00067.22 KFX92659.1 - 1.1e-28 100.2 0.0 2.1e-28 99.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S64 PF08192.11 KFX92660.1 - 1.6e-09 36.8 0.2 2.2e-08 33.1 0.2 2.0 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 KFX92660.1 - 2.7e-06 28.4 0.0 4.5e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 KFX92660.1 - 0.039 13.1 0.5 0.081 12.1 0.1 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Fungal_trans_2 PF11951.8 KFX92661.1 - 5.6e-44 150.5 0.0 7.8e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92661.1 - 2.2e-08 34.1 11.2 4.1e-08 33.2 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KFX92661.1 - 0.15 12.0 6.2 0.71 9.9 6.2 2.3 1 0 0 1 1 1 0 AT hook motif Pyrophosphatase PF00719.19 KFX92666.1 - 4e-58 195.7 0.1 5.1e-58 195.4 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 KFX92667.1 - 4.6e-47 160.6 0.0 1.7e-46 158.7 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ldh_2 PF02615.14 KFX92668.1 - 2e-91 306.6 1.9 2.3e-91 306.4 1.9 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_2 PF03446.15 KFX92669.1 - 3.9e-33 114.9 0.0 5.1e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFX92669.1 - 3.4e-18 66.1 0.0 5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFX92669.1 - 0.00069 20.1 0.0 0.0026 18.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KFX92669.1 - 0.025 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KFX92669.1 - 0.051 14.4 0.0 0.088 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lactamase_B PF00753.27 KFX92671.1 - 1.1e-06 28.8 2.2 3.1e-06 27.3 2.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX92671.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.20 KFX92672.1 - 1.1e-19 70.2 0.2 3.5e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 KFX92673.1 - 1.2e-27 96.8 28.9 1.7e-27 96.3 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PNTB PF02233.16 KFX92673.1 - 0.26 10.2 6.8 0.075 11.9 1.1 2.1 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit FAD_binding_2 PF00890.24 KFX92674.1 - 1.5e-40 139.6 0.1 1e-39 136.8 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX92674.1 - 6.1e-10 39.0 0.1 8.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 KFX92674.1 - 1.1e-07 31.8 0.5 1.1e-07 31.8 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX92674.1 - 6.4e-06 25.1 5.2 0.0022 16.8 0.1 3.1 3 0 0 3 3 3 3 HI0933-like protein GIDA PF01134.22 KFX92674.1 - 0.00099 18.3 5.1 0.01 14.9 0.4 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFX92674.1 - 0.00099 18.4 1.9 0.028 13.6 2.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX92674.1 - 0.0099 15.1 0.1 0.051 12.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 KFX92674.1 - 0.024 14.0 0.3 0.18 11.1 0.2 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 KFX92674.1 - 0.031 13.5 0.2 4.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX92674.1 - 0.066 13.4 0.4 0.2 11.9 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 KFX92675.1 - 1e-153 512.2 0.1 1.2e-153 512.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FtsZ_C PF12327.8 KFX92675.1 - 0.035 14.4 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DUF1487 PF07368.11 KFX92675.1 - 0.17 11.3 0.0 0.55 9.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Fungal_trans PF04082.18 KFX92676.1 - 3.2e-22 78.8 0.0 5.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92676.1 - 1.5e-07 31.4 13.2 3e-07 30.4 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KFX92677.1 - 3.7e-133 444.4 0.1 4.3e-133 444.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFX92677.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cullin PF00888.22 KFX92678.1 - 1.1e-23 83.8 0.0 1.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KFX92678.1 - 4.8e-19 68.6 1.6 6.8e-19 68.1 0.1 2.1 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 Sugar_tr PF00083.24 KFX92679.1 - 1.2e-116 390.3 14.1 2.4e-116 389.3 14.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX92679.1 - 2.5e-24 85.9 43.1 9.7e-23 80.6 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX92679.1 - 0.00045 18.8 3.6 0.00045 18.8 3.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.20 KFX92679.1 - 0.07 12.7 4.6 0.11 12.0 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 TPR_11 PF13414.6 KFX92679.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 TPR repeat DUF1717 PF05414.11 KFX92685.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) RNA_pol_Rpb1_R PF05001.13 KFX92686.1 - 0.0046 17.2 3.6 0.0046 17.2 3.6 4.7 4 1 0 5 5 5 1 RNA polymerase Rpb1 C-terminal repeat Cgr1 PF03879.14 KFX92686.1 - 0.27 11.6 0.6 0.44 10.9 0.6 1.3 1 0 0 1 1 1 0 Cgr1 family Scytalone_dh PF02982.14 KFX92687.1 - 9.5e-55 184.8 0.2 1.5e-54 184.2 0.2 1.2 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KFX92687.1 - 0.035 14.2 0.0 0.061 13.5 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain WD40_alt PF14077.6 KFX92687.1 - 0.073 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif zf-C2H2 PF00096.26 KFX92688.1 - 6.1e-08 32.7 13.0 0.00013 22.3 1.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KFX92688.1 - 7.5e-05 22.8 9.5 7.5e-05 22.8 9.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KFX92688.1 - 8.5e-05 23.1 11.8 0.0076 17.0 1.4 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX92688.1 - 0.03 14.8 11.2 0.028 14.9 3.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFX92688.1 - 0.03 14.6 3.7 0.29 11.5 0.5 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX92688.1 - 0.07 13.6 4.0 2.4 8.7 0.5 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KFX92688.1 - 0.39 10.5 6.5 9.9 6.0 1.6 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFX92688.1 - 1.3 9.1 4.7 11 6.1 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.7 KFX92688.1 - 2 8.5 11.0 0.13 12.3 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon adh_short_C2 PF13561.6 KFX92689.1 - 6e-52 176.5 0.0 1e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX92689.1 - 2.8e-45 154.2 0.0 4e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX92689.1 - 2.5e-10 40.6 0.0 4.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX92689.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFX92689.1 - 0.2 10.9 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.22 KFX92690.1 - 3.1e-50 171.3 0.0 7.3e-50 170.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Cu-oxidase_3 PF07732.15 KFX92691.1 - 3.6e-42 143.1 0.7 3.6e-42 143.1 0.7 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX92691.1 - 8.4e-29 100.1 11.5 7.8e-28 96.9 1.9 4.2 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KFX92691.1 - 1.8e-22 80.2 4.6 5e-22 78.7 0.0 3.5 4 1 1 5 5 5 1 Multicopper oxidase UEV PF05743.13 KFX92693.1 - 1.9e-37 127.8 0.0 2.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 UEV domain RNA_pol_Rpb2_6 PF00562.28 KFX92694.1 - 6.7e-123 410.6 0.1 1.2e-122 409.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFX92694.1 - 1.3e-59 201.1 0.0 4.2e-59 199.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFX92694.1 - 4.2e-49 166.8 0.0 8.5e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KFX92694.1 - 1.1e-25 89.6 0.1 2.5e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KFX92694.1 - 3.3e-24 85.0 1.1 6.5e-24 84.0 0.4 2.0 2 0 0 2 2 1 1 RNA polymerase Rpb2, domain 4 ADH_N PF08240.12 KFX92694.1 - 5.8e-24 84.1 3.7 2.5e-23 82.0 4.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb2_5 PF04567.17 KFX92694.1 - 1.3e-21 76.9 0.1 3.2e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.26 KFX92694.1 - 1.3e-18 67.3 0.0 2.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX92694.1 - 1.1e-08 36.2 0.0 2.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX92694.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_Rpb2_7 PF04560.20 KFX92694.1 - 0.025 15.0 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 PET117 PF15786.5 KFX92695.1 - 2.1e-25 88.8 2.1 2.4e-25 88.6 2.1 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KFX92696.1 - 1.8e-32 112.0 15.4 2.1e-32 111.8 15.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KFX92696.1 - 0.0038 17.3 18.7 0.0064 16.6 9.2 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 KFX92696.1 - 0.015 15.7 14.2 0.024 15.0 14.2 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF1834 PF08873.11 KFX92696.1 - 0.053 13.3 0.9 0.073 12.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF3552 PF12072.8 KFX92696.1 - 0.13 11.7 19.6 0.025 14.0 12.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) PNISR PF15996.5 KFX92696.1 - 0.17 12.2 11.8 0.18 12.0 11.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF2203 PF09969.9 KFX92696.1 - 0.24 12.1 4.9 0.33 11.7 4.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATP11 PF06644.11 KFX92696.1 - 0.33 10.7 10.7 0.41 10.4 10.7 1.0 1 0 0 1 1 1 0 ATP11 protein RRF PF01765.19 KFX92696.1 - 0.47 10.4 13.7 0.54 10.2 12.7 1.7 1 1 1 2 2 2 0 Ribosome recycling factor HOIP-UBA PF16678.5 KFX92696.1 - 0.49 10.4 6.5 0.98 9.4 6.6 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair Atrophin-1 PF03154.15 KFX92696.1 - 1.2 7.3 6.3 1.2 7.3 6.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Atg14 PF10186.9 KFX92696.1 - 3.3 6.7 8.0 3.5 6.6 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 vATP-synt_E PF01991.18 KFX92696.1 - 4.8 6.5 18.7 71 2.7 18.8 2.0 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF4407 PF14362.6 KFX92696.1 - 5 6.4 8.8 5.4 6.3 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arrestin_N PF00339.29 KFX92697.1 - 6.1e-11 42.6 0.1 6e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF676 PF05057.14 KFX92697.1 - 2.4e-05 23.9 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 KFX92697.1 - 3.9e-05 23.6 0.0 6.8e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFX92697.1 - 5e-05 23.1 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFX92697.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KFX92697.1 - 0.024 14.3 0.1 0.35 10.5 0.1 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 KFX92697.1 - 0.039 13.5 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) p47_phox_C PF08944.11 KFX92697.1 - 0.11 11.9 1.0 0.3 10.5 1.0 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain RPA43_OB PF17875.1 KFX92699.1 - 5.2e-31 107.8 11.3 1.2e-29 103.4 0.6 3.4 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KFX92699.1 - 1e-07 32.2 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AIF_C PF14721.6 KFX92699.1 - 4.9 7.5 5.5 40 4.6 0.0 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ras PF00071.22 KFX92705.1 - 7.6e-56 188.2 0.0 8.8e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX92705.1 - 8e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX92705.1 - 3.7e-07 29.8 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFX92705.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 KFX92705.1 - 0.034 14.4 0.0 0.14 12.4 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 KFX92705.1 - 0.069 12.3 0.1 0.82 8.8 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KFX92705.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribonuc_red_lgC PF02867.15 KFX92706.1 - 2.3e-189 630.3 0.0 3.2e-189 629.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KFX92706.1 - 1.3e-25 89.2 0.1 3.2e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KFX92706.1 - 3.2e-15 56.5 0.1 8.5e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain SET PF00856.28 KFX92707.1 - 1.6e-12 48.2 0.0 4.2e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 SET domain DUF3328 PF11807.8 KFX92714.1 - 1.1e-15 58.1 0.1 8.8e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.7 KFX92715.1 - 4.3e-19 69.6 0.0 5.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX92715.1 - 1.9e-08 34.5 0.0 8.7e-07 29.2 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFX92715.1 - 0.0041 17.1 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein ELK PF03789.13 KFX92715.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 ELK domain Acetyltransf_8 PF13523.6 KFX92715.1 - 0.17 11.6 0.0 0.79 9.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Vps54 PF07928.12 KFX92717.1 - 2.7e-45 154.1 0.0 3.8e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KFX92717.1 - 0.0053 16.6 0.0 0.0075 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Acetyltransf_10 PF13673.7 KFX92721.1 - 1.3e-09 38.0 0.0 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX92721.1 - 2e-07 31.3 0.0 2.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX92721.1 - 1.4e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX92721.1 - 0.00024 21.2 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX92721.1 - 0.0041 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFX92721.1 - 0.03 14.3 0.0 0.076 13.0 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein DNA_pol_B_palm PF14792.6 KFX92722.1 - 3.6e-35 120.6 0.0 6.2e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KFX92722.1 - 6.3e-26 90.3 0.1 5.5e-24 84.1 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFX92722.1 - 3.6e-18 65.1 0.4 8.3e-18 64.0 0.4 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFX92722.1 - 1.8e-16 60.2 1.2 4.1e-16 59.1 0.5 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 KFX92722.1 - 0.041 14.3 0.0 0.093 13.1 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HHH_2 PF12826.7 KFX92722.1 - 0.049 13.7 0.2 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 KFX92722.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 KFX92722.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KFX92722.1 - 0.12 13.1 0.5 1.6 9.4 0.0 2.6 2 1 0 2 2 2 0 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 KFX92722.1 - 0.2 12.3 0.7 2.4 8.8 0.0 2.4 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Sugar_tr PF00083.24 KFX92723.1 - 2.1e-97 326.8 26.3 2.5e-97 326.6 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX92723.1 - 7.6e-40 136.9 42.1 6.6e-36 124.0 19.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX92723.1 - 0.0072 14.9 2.4 0.0072 14.9 2.4 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein Asn_synthase PF00733.21 KFX92724.1 - 2.1e-15 57.2 0.1 1.8e-05 24.6 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFX92724.1 - 9.4e-07 28.8 0.0 2.5e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFX92724.1 - 0.0005 20.3 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.18 KFX92725.1 - 1.5e-29 102.3 0.1 2.6e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFX92725.1 - 2.5e-15 56.5 0.1 5.3e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KFX92725.1 - 2.1e-10 40.1 0.0 4.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain TPR_9 PF13371.6 KFX92726.1 - 0.00018 21.6 0.0 0.00061 19.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92726.1 - 0.0017 18.1 0.0 0.0058 16.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFX92726.1 - 0.0044 16.4 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 KFX92726.1 - 0.007 16.4 2.3 0.0095 16.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX92726.1 - 0.043 14.1 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 KFX92727.1 - 3.2e-54 183.1 0.0 7.4e-53 178.7 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFX92727.1 - 5.2e-49 166.0 0.1 3.4e-47 160.1 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX92727.1 - 3.1e-39 133.8 0.2 3.1e-39 133.8 0.2 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.25 KFX92728.1 - 4.6e-49 167.1 0.0 6.7e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92728.1 - 7.1e-31 107.4 0.0 1.1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFX92728.1 - 0.00046 19.9 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFX92728.1 - 0.00071 19.6 0.1 0.0027 17.6 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX92728.1 - 0.003 16.9 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX92728.1 - 0.0032 16.8 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFX92728.1 - 0.19 10.6 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_6 PF01341.17 KFX92729.1 - 8.6e-96 321.3 0.1 1.1e-95 320.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CSN8_PSD8_EIF3K PF10075.9 KFX92730.1 - 5.7e-05 23.1 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KFX92730.1 - 0.11 11.8 0.3 0.16 11.3 0.3 1.3 1 0 0 1 1 1 0 SAC3/GANP family HlyIII PF03006.20 KFX92731.1 - 1.4e-61 208.1 13.3 1.6e-61 207.9 13.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related adh_short_C2 PF13561.6 KFX92732.1 - 7.5e-47 159.8 6.3 1.3e-39 136.1 5.9 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX92732.1 - 9.2e-45 152.5 5.6 1.2e-44 152.1 5.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX92732.1 - 5.4e-16 59.0 1.2 7.4e-16 58.6 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFX92732.1 - 0.0033 17.3 1.3 0.0052 16.7 1.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFX92732.1 - 0.0077 16.3 1.0 0.013 15.6 0.5 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX92732.1 - 0.043 14.1 0.2 0.064 13.5 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glycos_transf_2 PF00535.26 KFX92733.1 - 2.1e-30 105.7 0.0 2.6e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFX92733.1 - 9.2e-10 38.8 0.0 1.2e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFX92733.1 - 4.1e-05 23.2 0.0 5.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFX92733.1 - 0.052 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KFX92733.1 - 0.059 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 TFR_dimer PF04253.15 KFX92734.1 - 4.5e-31 107.5 0.0 9.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFX92734.1 - 2.4e-23 82.8 0.0 4.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX92734.1 - 4.3e-12 45.9 0.0 8.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFX92734.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cyt-b5 PF00173.28 KFX92735.1 - 6.2e-13 48.7 0.0 8.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMA7 PF09072.10 KFX92736.1 - 4e-24 85.2 20.3 4.4e-24 85.1 20.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 KFX92737.1 - 7.6e-54 182.8 0.1 1.1e-53 182.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92737.1 - 4e-24 85.3 0.2 1.2e-23 83.8 0.3 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFX92737.1 - 0.0065 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFX92737.1 - 0.063 12.9 0.2 0.16 11.5 0.2 1.7 1 1 0 1 1 1 0 RIO1 family TPR_19 PF14559.6 KFX92738.1 - 1.6e-07 31.7 0.3 2.4e-07 31.2 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KFX92738.1 - 7.1e-05 22.4 0.1 8e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.6 KFX92738.1 - 0.0019 18.8 0.1 0.062 14.2 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX92738.1 - 0.0022 18.5 0.1 0.13 12.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX92738.1 - 0.0086 16.1 0.2 0.56 10.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX92738.1 - 0.012 15.9 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX92738.1 - 0.049 14.3 0.0 15 6.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Ask1 PF08655.10 KFX92742.1 - 3.5e-31 106.9 0.1 4.9e-31 106.4 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Ask1 Prok-JAB PF14464.6 KFX92742.1 - 0.0084 15.9 0.3 0.014 15.2 0.3 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3073 PF11273.8 KFX92742.1 - 0.37 11.6 3.9 0.64 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) O-FucT PF10250.9 KFX92743.1 - 1.2e-10 41.7 0.0 7.5e-07 29.2 0.0 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase 3HCDH_N PF02737.18 KFX92744.1 - 4.8e-42 143.9 0.0 7.2e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFX92744.1 - 9.8e-10 38.9 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 KFX92744.1 - 8.3e-05 22.0 0.0 0.00025 20.4 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFX92744.1 - 0.037 14.2 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX92744.1 - 0.2 12.3 0.1 1.4 9.6 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF1015 PF06245.11 KFX92744.1 - 0.23 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) GH131_N PF18271.1 KFX92745.1 - 2e-62 211.2 0.6 2.5e-62 210.9 0.6 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KFX92745.1 - 2.8e-13 49.6 13.2 6.5e-13 48.4 13.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX92745.1 - 0.19 12.0 3.0 0.35 11.1 3.0 1.4 1 0 0 1 1 1 0 Toxin 7 DUF3074 PF11274.8 KFX92748.1 - 1.4e-33 116.4 0.1 1.8e-33 116.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Formyl_trans_N PF00551.19 KFX92749.1 - 1e-38 132.9 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 KFX92749.1 - 0.046 13.6 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase GDI PF00996.18 KFX92756.1 - 1.5e-186 620.2 0.0 1.8e-186 619.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.13 KFX92756.1 - 1.3e-20 73.3 0.3 2.5e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NAD_binding_8 PF13450.6 KFX92756.1 - 0.07 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX92756.1 - 0.16 12.5 0.2 0.87 10.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2_2 PF13465.6 KFX92757.1 - 3.2e-06 27.3 7.1 9.2e-06 25.9 1.1 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.12 KFX92757.1 - 0.00077 19.7 4.1 0.0015 18.8 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFX92757.1 - 0.0014 19.3 14.7 0.12 13.2 5.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3464 PF11947.8 KFX92757.1 - 0.047 13.5 6.6 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 zf-C2H2_jaz PF12171.8 KFX92757.1 - 0.11 12.8 3.0 11 6.5 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TERB2 PF15101.6 KFX92757.1 - 0.29 11.1 7.6 13 5.8 9.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Presenilin PF01080.17 KFX92757.1 - 0.54 9.0 2.9 0.88 8.3 2.9 1.3 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 KFX92765.1 - 8.1e-07 28.7 0.0 0.0013 18.1 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92765.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.7 2 1 0 2 2 2 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX92765.1 - 0.049 12.4 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1768 PF08719.11 KFX92767.1 - 4.6e-53 179.8 0.0 5.4e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glutaredoxin PF00462.24 KFX92775.1 - 1.2e-09 38.3 0.0 2e-09 37.5 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin CYSTM PF12734.7 KFX92776.1 - 4.4e-12 46.1 24.2 4.4e-12 46.1 24.2 4.5 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 KFX92776.1 - 0.53 10.9 6.2 0.59 10.8 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region A_deaminase PF00962.22 KFX92777.1 - 2.5e-122 408.3 0.1 3.6e-122 407.8 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KFX92778.1 - 4.4e-100 334.8 7.2 5.3e-100 334.5 7.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFX92778.1 - 4.7e-06 26.0 7.2 8.8e-06 25.1 7.2 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter Tetraspanin PF00335.20 KFX92778.1 - 0.023 14.4 0.1 0.023 14.4 0.1 2.2 2 0 0 2 2 2 0 Tetraspanin family TMEM100 PF16311.5 KFX92778.1 - 0.028 14.0 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Pox_A14 PF05767.12 KFX92778.1 - 0.037 14.2 0.3 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Romo1 PF10247.9 KFX92778.1 - 0.039 14.3 2.2 8.5 6.8 0.4 2.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 EamA PF00892.20 KFX92778.1 - 0.13 12.4 30.3 0.18 11.9 10.7 4.0 2 2 1 3 3 3 0 EamA-like transporter family TMEM234 PF10639.9 KFX92778.1 - 0.19 11.8 2.9 0.99 9.5 0.4 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 LSM PF01423.22 KFX92780.1 - 2.4e-18 65.6 0.5 3.1e-18 65.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFX92780.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KFX92780.1 - 0.083 13.0 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain DRMBL PF07522.14 KFX92781.1 - 7.4e-36 122.7 0.0 1.6e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KFX92781.1 - 5.4e-05 22.8 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rad50_zn_hook PF04423.14 KFX92781.1 - 0.058 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Sugar_tr PF00083.24 KFX92783.1 - 6.5e-46 157.1 8.9 8.2e-46 156.8 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX92783.1 - 1.1e-15 57.5 15.8 1.5e-15 57.0 15.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX92783.1 - 1.8e-07 30.1 3.6 1.8e-07 30.1 3.6 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_4 PF06779.14 KFX92783.1 - 0.00077 18.8 7.2 0.0015 17.9 7.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4112 PF13430.6 KFX92783.1 - 0.034 14.4 0.3 0.15 12.3 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4112) MFS_1_like PF12832.7 KFX92783.1 - 0.051 12.4 4.1 0.073 11.9 4.1 1.2 1 0 0 1 1 1 0 MFS_1 like family OATP PF03137.20 KFX92783.1 - 0.065 11.5 5.5 0.39 8.9 1.7 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2070 PF09843.9 KFX92783.1 - 3.8 5.7 4.5 5.6 5.1 4.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) STE3 PF02076.15 KFX92788.1 - 2.8e-84 282.8 21.5 3.2e-84 282.6 21.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4131 PF13567.6 KFX92788.1 - 0.023 14.4 0.9 0.023 14.4 0.9 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4131) Mito_carr PF00153.27 KFX92795.1 - 1.7e-30 104.8 0.2 7.7e-19 67.4 0.2 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 KFX92798.1 - 8.6e-16 57.9 2.7 3.4e-09 36.7 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX92798.1 - 3.7e-09 36.7 0.7 5.6e-05 23.3 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 KFX92798.1 - 0.043 13.8 19.9 0.065 13.2 19.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KFX92798.1 - 0.11 12.1 12.3 0.19 11.3 12.3 1.5 1 0 0 1 1 1 0 Spt20 family Glyco_hydro_16 PF00722.21 KFX92802.1 - 7.7e-46 155.8 3.5 1.1e-45 155.3 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KFX92802.1 - 0.049 14.1 12.5 0.1 13.1 12.5 1.5 1 0 0 1 1 1 0 Chitin recognition protein zf-C2H2_3 PF13878.6 KFX92804.1 - 4e-10 39.4 0.2 7e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO ASF1_hist_chap PF04729.13 KFX92810.1 - 8.6e-69 230.4 0.0 1.4e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone zinc_ribbon_9 PF14369.6 KFX92811.1 - 0.22 11.8 4.9 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 KFX92811.1 - 1.9 8.5 4.1 8.8 6.3 4.1 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ATXN-1_C PF12547.8 KFX92811.1 - 3.6 8.0 10.1 2.6 8.5 7.4 2.2 2 1 0 2 2 2 0 Capicua transcriptional repressor modulator GTP_EFTU PF00009.27 KFX92812.1 - 3.5e-32 111.5 8.8 5.2e-32 111.0 3.3 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFX92812.1 - 2.3e-26 91.9 0.3 1.1e-25 89.8 0.2 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFX92812.1 - 1.7e-08 34.5 1.1 3e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 KFX92812.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KFX92812.1 - 1.7e-05 24.8 0.6 0.00025 21.0 0.1 2.5 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 KFX92812.1 - 0.0012 18.3 0.5 0.0025 17.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KFX92812.1 - 0.0044 17.4 5.3 0.029 14.7 0.2 3.7 3 1 0 3 3 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KFX92812.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFX92812.1 - 0.016 14.7 0.3 0.055 13.0 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KFX92812.1 - 0.018 14.8 0.3 0.08 12.7 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KFX92812.1 - 0.036 14.1 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF1654 PF07867.11 KFX92812.1 - 0.067 12.9 0.5 0.23 11.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Roc PF08477.13 KFX92812.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 KFX92812.1 - 1.4 8.9 5.7 0.86 9.5 0.8 2.7 3 0 0 3 3 3 0 Elongation factor Tu domain 4 VHS PF00790.19 KFX92814.1 - 4.5e-45 153.0 0.0 1.7e-44 151.1 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFX92814.1 - 3.1e-20 72.5 0.1 3.1e-20 72.5 0.1 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KFX92814.1 - 1.4e-19 70.2 0.4 1.4e-19 70.2 0.4 2.0 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KFX92814.1 - 3e-07 29.9 0.1 1.1e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain Glyco_hydro_76 PF03663.14 KFX92819.1 - 7.3e-81 272.5 2.8 9.2e-81 272.2 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Rax2 PF12768.7 KFX92819.1 - 2.8e-05 23.7 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 KFX92819.1 - 0.00033 20.0 2.3 0.00082 18.7 2.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KFX92819.1 - 0.0075 16.4 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Podoplanin DAP10 PF07213.11 KFX92819.1 - 0.12 12.4 1.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein DUF347 PF03988.12 KFX92819.1 - 1.1 9.5 9.6 0.64 10.3 0.8 2.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Phage_holin_3_6 PF07332.11 KFX92819.1 - 1.6 8.8 5.1 14 5.8 1.9 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pyr_redox_2 PF07992.14 KFX92820.1 - 7e-19 68.2 0.1 8e-18 64.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX92820.1 - 2.9e-05 23.4 0.8 0.00068 18.8 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KFX92820.1 - 3.3e-05 23.9 1.4 0.22 11.5 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX92820.1 - 6.1e-05 22.4 0.6 0.027 13.7 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX92820.1 - 0.00024 20.0 0.1 0.021 13.5 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 KFX92820.1 - 0.0015 17.8 0.9 0.0027 17.0 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX92820.1 - 0.0024 17.5 1.7 0.0079 15.8 0.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX92820.1 - 0.0028 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFX92820.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX92820.1 - 0.0041 16.2 0.1 0.23 10.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KFX92820.1 - 0.01 14.9 4.4 0.13 11.3 0.9 2.6 2 1 0 3 3 3 0 Glucose inhibited division protein A SOG2 PF10428.9 KFX92821.1 - 0.0018 17.5 8.2 0.002 17.4 8.2 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein SKG6 PF08693.10 KFX92821.1 - 0.004 16.5 0.4 0.0081 15.6 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SPX PF03105.19 KFX92821.1 - 0.015 15.3 7.8 0.017 15.0 7.8 1.1 1 0 0 1 1 1 0 SPX domain Podoplanin PF05808.11 KFX92821.1 - 0.039 14.1 2.4 0.077 13.1 2.5 1.5 1 1 0 1 1 1 0 Podoplanin CD34_antigen PF06365.12 KFX92821.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family CTV_P6 PF06706.11 KFX92821.1 - 0.05 13.3 1.2 0.097 12.4 1.2 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein PRCC PF10253.9 KFX92821.1 - 0.051 14.4 7.0 0.067 14.0 7.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ndc1_Nup PF09531.10 KFX92821.1 - 0.3 9.7 9.5 0.39 9.3 9.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KFX92821.1 - 0.47 9.3 3.2 0.5 9.1 3.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCOM2 PF15328.6 KFX92821.1 - 1.2 9.5 7.7 1.6 9.0 7.7 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF2650 PF10853.8 KFX92821.1 - 4.2 7.2 8.0 8.8 6.1 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Podoplanin PF05808.11 KFX92822.1 - 0.00012 22.2 4.0 0.00022 21.4 4.0 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.15 KFX92822.1 - 0.0013 18.5 0.4 0.0025 17.6 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 KFX92822.1 - 0.017 14.5 0.6 0.043 13.2 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KFX92822.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.11 KFX92822.1 - 0.95 7.5 11.0 1.1 7.2 11.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 KFX92823.1 - 2.8e-22 79.1 41.1 2.8e-22 79.1 41.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KFX92824.1 - 2.9e-11 43.1 0.0 4.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain SLATT_fungal PF18142.1 KFX92826.1 - 3.8e-32 110.8 0.2 1.2e-31 109.2 0.0 1.8 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain Cellulase PF00150.18 KFX92827.1 - 4.1e-14 52.7 5.8 6.2e-14 52.1 5.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.9 KFX92828.1 - 5.2e-34 116.5 0.0 1.2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Piwi PF02171.17 KFX92829.1 - 2.8e-73 246.8 1.1 4.7e-73 246.1 1.1 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFX92829.1 - 4.8e-17 62.9 0.1 4.7e-16 59.7 0.0 2.6 3 0 0 3 3 3 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFX92829.1 - 1.2e-14 53.7 0.0 2.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFX92829.1 - 2.9e-14 53.1 0.3 7.4e-14 51.7 0.1 1.8 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 KFX92829.1 - 2.2e-08 34.3 0.0 4.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain Suf PF05843.14 KFX92830.1 - 1.7e-93 313.8 1.6 1.8e-89 300.6 0.0 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.6 KFX92830.1 - 0.0057 17.3 0.3 0.089 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.16 KFX92830.1 - 0.0089 16.0 0.1 0.51 10.4 0.2 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFX92830.1 - 0.0095 16.7 0.4 4.3 8.4 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFX92830.1 - 0.23 10.6 2.6 12 4.9 0.1 3.8 2 1 1 4 4 4 0 NRDE-2, necessary for RNA interference PP28 PF10252.9 KFX92832.1 - 1.1e-32 112.3 10.2 1.1e-32 112.3 10.2 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Abhydrolase_6 PF12697.7 KFX92834.1 - 1.9e-12 48.3 2.1 2.5e-12 47.9 1.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX92834.1 - 3.1e-11 43.4 0.8 1.9e-10 40.9 0.3 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX92834.1 - 3.7e-08 33.1 0.0 8.8e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX92834.1 - 5.9e-08 32.3 0.2 7.1e-07 28.7 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFX92834.1 - 4.9e-05 23.3 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KFX92834.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Ser_hydrolase PF06821.13 KFX92834.1 - 0.015 15.1 0.7 0.022 14.6 0.1 1.5 2 0 0 2 2 2 0 Serine hydrolase AbrB PF05145.12 KFX92834.1 - 0.02 13.9 1.9 0.035 13.1 1.9 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Abhydrolase_2 PF02230.16 KFX92834.1 - 0.027 14.3 0.1 0.58 9.9 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KFX92834.1 - 0.058 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFX92834.1 - 0.07 12.8 0.1 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KFX92834.1 - 0.1 12.3 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1072 PF06380.11 KFX92834.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) NMT_C PF02799.15 KFX92835.1 - 4.8e-88 294.1 0.0 7e-88 293.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFX92835.1 - 6.9e-73 243.8 0.2 1.3e-72 242.9 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Molydop_binding PF01568.21 KFX92835.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain NTP_transf_9 PF04248.12 KFX92835.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) RhoGAP PF00620.27 KFX92835.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Acetyltransf_9 PF13527.7 KFX92835.1 - 0.17 12.0 0.0 1 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SOG2 PF10428.9 KFX92836.1 - 0.0049 16.1 4.6 0.0061 15.8 4.6 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Herpes_UL4 PF03277.13 KFX92836.1 - 0.093 12.3 1.2 0.17 11.5 1.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL4 family WSC PF01822.19 KFX92837.1 - 1.2e-17 63.9 6.8 1.9e-17 63.2 6.8 1.3 1 0 0 1 1 1 1 WSC domain DUF3439 PF11921.8 KFX92837.1 - 1.2 9.1 10.4 0.74 9.8 8.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 KFX92839.1 - 7.3e-41 138.7 0.2 3.6e-12 46.7 0.2 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX92839.1 - 1.4e-32 111.6 5.8 3.2e-08 33.9 0.1 6.3 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92839.1 - 2.8e-32 107.1 3.3 0.00024 21.3 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KFX92839.1 - 2.9e-27 93.9 6.0 0.0019 18.5 0.1 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFX92839.1 - 1.4e-23 82.7 8.0 2e-06 27.9 0.4 6.6 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KFX92839.1 - 0.0013 18.2 1.0 0.012 15.0 1.0 2.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RXLR_WY PF18634.1 KFX92839.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain COesterase PF00135.28 KFX92840.1 - 1.6e-82 278.1 0.0 2e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX92840.1 - 0.00011 22.1 0.0 0.00066 19.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX92840.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family dUTPase PF00692.19 KFX92841.1 - 4.3e-13 49.1 0.0 6.4e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KFX92841.1 - 0.0001 21.2 0.0 0.00018 20.4 0.0 1.4 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Sulfatase PF00884.23 KFX92842.1 - 6.1e-64 216.3 0.4 8e-64 215.9 0.4 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFX92842.1 - 0.3 10.6 5.2 0.61 9.6 2.1 2.4 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KFX92843.1 - 2.7e-21 75.9 32.8 1.4e-18 67.0 12.9 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92843.1 - 2e-05 23.7 1.3 4.8e-05 22.4 1.3 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter SecE PF00584.20 KFX92843.1 - 0.31 11.0 2.1 25 4.9 0.2 2.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex PhoR PF11808.8 KFX92843.1 - 7.5 7.0 0.0 7.5 7.0 0.0 4.0 5 0 0 5 5 5 0 Phosphate regulon sensor protein PhoR Abhydrolase_1 PF00561.20 KFX92845.1 - 2.1e-21 76.7 0.0 1e-20 74.5 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX92845.1 - 5.8e-15 55.2 0.0 8.9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX92845.1 - 1.2e-14 55.4 0.0 1.7e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 KFX92845.1 - 6.2e-06 25.5 0.0 8.5e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 KFX92845.1 - 1.3e-05 24.1 0.0 2.8e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Ndr family PGAP1 PF07819.13 KFX92845.1 - 0.00085 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 KFX92845.1 - 0.0022 17.3 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KFX92845.1 - 0.045 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFX92845.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 KFX92845.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KFX92845.1 - 0.071 12.7 0.1 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KFX92845.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 KFX92845.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KFX92845.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) APH PF01636.23 KFX92847.1 - 4.4e-11 43.2 0.3 2e-10 41.0 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFX92847.1 - 1e-06 28.3 0.0 0.00015 21.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.20 KFX92847.1 - 2.3e-06 27.3 0.1 6.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFX92847.1 - 0.00021 20.7 0.0 0.00069 19.0 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX92847.1 - 0.0007 19.2 0.3 0.0032 17.1 0.0 2.0 2 1 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KFX92847.1 - 0.033 13.5 0.0 0.072 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase SNARE PF05739.19 KFX92851.1 - 1.2e-11 44.4 0.1 2.7e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KFX92851.1 - 6.2e-11 41.2 1.0 2.2e-10 39.4 1.0 2.1 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KFX92851.1 - 0.00074 19.3 10.7 0.0061 16.2 0.3 3.2 2 1 1 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 KFX92851.1 - 0.018 15.3 2.3 0.022 15.0 0.2 2.2 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Prominin PF05478.11 KFX92851.1 - 0.02 12.9 0.2 1.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Prominin MCPsignal PF00015.21 KFX92851.1 - 0.029 14.2 7.9 0.98 9.2 0.2 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 KFX92851.1 - 0.059 13.7 6.7 1.8 8.9 0.3 4.0 4 1 1 5 5 5 0 Uncharacterized conserved protein DUF4988 PF16378.5 KFX92851.1 - 0.13 11.9 2.6 5.5 6.6 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KFX92851.1 - 0.21 12.1 8.0 5.4 7.6 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 KFX92851.1 - 2.8 8.1 5.5 2 8.5 0.4 3.2 4 0 0 4 4 4 0 Tetramerisation domain of TRPM DUF948 PF06103.11 KFX92851.1 - 4.5 7.6 6.5 13 6.1 0.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 KFX92851.1 - 7.8 7.5 9.5 5.7 7.9 0.6 2.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain CBS PF00571.28 KFX92852.1 - 0.00013 22.3 0.1 0.05 14.1 0.0 3.0 2 1 1 3 3 3 2 CBS domain Glyco_hydro_43 PF04616.14 KFX92853.1 - 1.4e-32 113.2 3.0 1.8e-32 112.8 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RR_TM4-6 PF06459.12 KFX92856.1 - 0.2 11.5 6.0 0.26 11.1 6.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIFIN PF02009.16 KFX92856.1 - 0.48 10.3 6.4 0.54 10.1 6.4 1.1 1 0 0 1 1 1 0 Rifin NPR3 PF03666.13 KFX92856.1 - 1.1 8.0 7.9 1.1 8.0 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPP4R2 PF09184.11 KFX92856.1 - 2.1 7.9 13.2 2.4 7.7 13.2 1.0 1 0 0 1 1 1 0 PPP4R2 SOG2 PF10428.9 KFX92856.1 - 2.5 7.2 24.9 2.9 7.0 24.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF966 PF06136.13 KFX92856.1 - 3.4 7.3 14.2 3.8 7.1 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.6 KFX92856.1 - 6.9 7.2 11.0 8 7.0 11.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pneumo_att_G PF05539.11 KFX92856.1 - 7.9 6.0 26.9 8.8 5.8 26.9 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3425 PF11905.8 KFX92857.1 - 1.1e-07 31.8 0.0 2.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFX92857.1 - 0.00011 22.3 13.1 0.00026 21.0 13.1 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX92857.1 - 0.7 10.0 16.3 31 4.8 16.3 2.2 1 1 0 1 1 1 0 Basic region leucine zipper p450 PF00067.22 KFX92858.1 - 7.1e-45 153.6 0.0 1.5e-44 152.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FlbT PF07378.11 KFX92858.1 - 0.22 11.6 0.2 1.2 9.2 0.0 2.2 3 0 0 3 3 3 0 Flagellar protein FlbT DUF4148 PF13663.6 KFX92858.1 - 0.31 11.2 2.1 0.52 10.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Fungal_trans_2 PF11951.8 KFX92860.1 - 9e-08 31.3 7.4 1.4e-07 30.7 7.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92860.1 - 9.8e-08 32.0 11.0 9.8e-08 32.0 11.0 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 KFX92863.1 - 7.9e-09 35.9 3.1 1.3e-08 35.2 2.4 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Exo5 PF09810.9 KFX92867.1 - 2e-77 261.2 0.0 2.3e-77 261.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KFX92867.1 - 0.089 12.7 0.0 0.75 9.7 0.0 2.0 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily EamA PF00892.20 KFX92871.1 - 2.5e-05 24.5 17.0 2.5e-05 24.5 17.0 1.5 2 0 0 2 2 2 1 EamA-like transporter family Sugar_tr PF00083.24 KFX92872.1 - 1.3e-75 255.0 29.0 1.5e-75 254.8 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX92872.1 - 1.6e-16 60.2 28.3 1.6e-16 60.2 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX92872.1 - 0.041 12.8 18.2 0.011 14.6 7.5 2.3 2 0 0 2 2 2 0 MFS_1 like family Peptidase_S9 PF00326.21 KFX92873.1 - 5.3e-15 55.5 0.0 6.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFX92873.1 - 4.2e-07 30.0 0.0 2.4e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KFX92873.1 - 7.6e-07 28.9 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFX92873.1 - 5.2e-05 22.6 0.0 0.022 14.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX92873.1 - 0.0018 18.0 0.0 0.11 12.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFX92873.1 - 0.0023 17.6 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KFX92873.1 - 0.044 13.4 0.0 3.1 7.3 0.1 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.9 KFX92873.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 GFO_IDH_MocA PF01408.22 KFX92875.1 - 2.3e-18 67.2 0.0 4.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX92875.1 - 2.2e-17 63.1 0.1 2e-16 60.0 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX92875.1 - 0.0032 18.1 0.0 0.0048 17.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.20 KFX92875.1 - 0.1 11.1 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme UBD PF16455.5 KFX92877.1 - 1.6e-35 121.5 0.0 2.5e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFX92877.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX92877.1 - 0.046 13.6 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_hydro_11 PF00457.17 KFX92878.1 - 8.2e-79 263.3 17.1 1.2e-78 262.8 17.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KFX92878.1 - 8.3e-11 41.7 16.8 2.5e-10 40.1 16.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX92878.1 - 0.56 10.5 9.5 1.3 9.4 9.5 1.6 1 1 0 1 1 1 0 Toxin 7 BTB PF00651.31 KFX92879.1 - 5e-08 33.2 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KFX92879.1 - 0.047 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Rhodanese_C PF12368.8 KFX92880.1 - 6.7e-11 42.4 8.4 2.1e-10 40.8 8.4 1.9 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 KFX92880.1 - 2.6e-10 40.5 0.0 9.1e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KFX92880.1 - 0.007 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain cEGF PF12662.7 KFX92880.1 - 0.42 10.6 5.7 0.094 12.7 1.2 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like Peptidase_S24 PF00717.23 KFX92881.1 - 8.3e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 KFX92882.1 - 1.2e-42 144.9 0.0 1.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX92882.1 - 2.1e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFX92882.1 - 0.017 15.4 0.2 0.019 15.2 0.1 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 KFX92882.1 - 0.12 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 UEV domain TRAM_LAG1_CLN8 PF03798.16 KFX92883.1 - 5.3e-42 143.8 18.3 5.3e-42 143.8 18.3 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFX92883.1 - 2.2e-21 75.2 0.1 2.2e-21 75.2 0.1 2.5 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 KFX92884.1 - 3.2e-34 118.4 25.1 4.9e-34 117.8 25.1 1.3 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.25 KFX92884.1 - 8.1e-28 97.5 0.0 1.1e-26 93.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain TRAM1 PF08390.11 KFX92884.1 - 5.8e-25 86.7 0.0 1.4e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Pkinase_Tyr PF07714.17 KFX92884.1 - 1.5e-06 27.7 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PET117 PF15786.5 KFX92884.1 - 0.067 13.5 0.3 0.18 12.1 0.3 1.7 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Glycos_transf_1 PF00534.20 KFX92885.1 - 3.7e-17 62.4 0.0 7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFX92885.1 - 4.3e-12 46.6 0.0 7.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KFX92885.1 - 0.18 12.2 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-Tim10_DDP PF02953.15 KFX92892.1 - 7e-20 70.4 2.6 1.1e-19 69.8 2.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KFX92892.1 - 0.036 13.8 2.5 1.1 9.0 0.2 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.27 KFX92893.1 - 7.2e-40 136.3 0.0 1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SOG2 PF10428.9 KFX92894.1 - 0.057 12.6 15.9 0.06 12.5 15.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PAP_assoc PF03828.19 KFX92896.1 - 2.3e-12 46.9 0.0 5.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFX92896.1 - 1.2e-05 25.5 0.1 7.8e-05 22.9 0.1 2.4 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFX92896.1 - 0.0026 17.8 0.0 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase RGS-like PF09128.11 KFX92896.1 - 0.005 16.6 0.3 0.005 16.6 0.3 1.7 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain TFIIF_alpha PF05793.12 KFX92897.1 - 2.4e-13 49.6 46.8 3.9e-13 48.8 42.5 2.5 1 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDI PF02234.19 KFX92897.1 - 9.3 6.5 7.1 0.96 9.7 0.8 2.8 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor AC_N PF16214.5 KFX92898.1 - 0.47 9.5 6.6 0.51 9.4 6.6 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Arrestin_C PF02752.22 KFX92901.1 - 3.8e-11 43.6 0.0 1e-10 42.2 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pol_alpha_B_N PF08418.10 KFX92905.1 - 5e-83 278.8 0.1 6.3e-83 278.5 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KFX92905.1 - 1e-36 126.3 0.0 1.4e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 KFX92906.1 - 7.3e-40 136.3 0.0 9.9e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX92906.1 - 3e-14 52.9 0.3 6.9e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFX92906.1 - 8.7e-05 22.7 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Chon_Sulph_att PF06566.11 KFX92906.1 - 1.2 8.9 7.0 2.8 7.7 7.0 1.5 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain TRAPP PF04051.16 KFX92907.1 - 1.5e-41 141.5 0.0 1.8e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.11 KFX92908.1 - 3.3e-32 110.5 0.3 3.8e-32 110.3 0.3 1.0 1 0 0 1 1 1 1 Apc13p protein zf-RING_2 PF13639.6 KFX92909.1 - 2.7e-05 24.4 3.6 2.7e-05 24.4 3.6 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KFX92909.1 - 0.0005 19.9 4.1 0.038 13.9 1.2 2.8 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFX92909.1 - 0.01 15.7 2.2 0.034 14.0 2.2 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX92909.1 - 0.12 12.4 2.0 0.38 10.8 2.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KFX92909.1 - 0.17 12.2 5.0 0.98 9.8 5.0 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFX92909.1 - 0.18 11.7 10.6 0.28 11.1 1.2 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX92909.1 - 0.2 11.7 1.4 2.2 8.4 1.4 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFX92909.1 - 0.49 10.4 4.7 0.53 10.3 2.5 2.3 2 1 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 KFX92909.1 - 0.84 9.8 5.2 1.1 9.4 3.7 2.1 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 KFX92909.1 - 1.1 9.5 6.7 38 4.6 0.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 KFX92909.1 - 2 8.3 4.9 11 6.0 0.8 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 KFX92909.1 - 3.3 7.9 8.2 11 6.3 5.1 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Kinesin PF00225.23 KFX92910.1 - 5.3e-112 374.0 0.0 5.3e-112 374.0 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFX92910.1 - 4.3e-25 88.4 0.1 1.1e-24 87.1 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 KFX92910.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain YabA PF06156.13 KFX92910.1 - 1 10.0 11.0 3.9 8.1 0.1 4.1 3 1 2 5 5 5 0 Initiation control protein YabA DUF5094 PF17015.5 KFX92910.1 - 1.8 8.6 10.7 5.7 7.0 5.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) OmpH PF03938.14 KFX92910.1 - 2.9 8.2 12.7 3.7 7.9 7.3 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 KFX92910.1 - 2.9 8.1 7.6 0.84 9.8 0.3 3.2 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 Fez1 PF06818.15 KFX92910.1 - 3.6 8.0 13.7 0.74 10.2 9.7 1.9 2 0 0 2 2 2 0 Fez1 PUL PF08324.11 KFX92911.1 - 6.4e-62 209.3 0.3 3.7e-61 206.8 0.3 1.9 2 0 0 2 2 2 1 PUL domain Peptidase_C97 PF05903.14 KFX92911.1 - 7.1e-34 116.8 0.0 1.1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KFX92911.1 - 1.1e-12 47.8 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFX92911.1 - 5.7e-06 26.3 0.0 9.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 KFX92911.1 - 0.00042 20.7 0.9 0.0043 17.5 0.7 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFX92911.1 - 0.0047 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFX92911.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 KFX92911.1 - 0.23 11.8 0.2 0.76 10.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like GDA1_CD39 PF01150.17 KFX92912.1 - 9.8e-96 321.0 0.0 1.2e-95 320.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 KFX92913.1 - 6.2e-08 32.4 0.0 1.7e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 AAA lid domain VHS PF00790.19 KFX92914.1 - 5.7e-38 129.9 0.8 8.3e-37 126.2 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KFX92914.1 - 1.5e-15 57.0 2.7 3.1e-15 56.1 2.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KFX92914.1 - 7.2e-06 25.6 12.1 0.0072 16.2 1.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KFX92914.1 - 4.7e-05 23.6 0.0 0.00014 22.1 0.0 1.9 1 0 0 1 1 1 1 GAT domain NUDIX PF00293.28 KFX92915.1 - 6e-14 52.2 0.1 1.6e-13 50.8 0.0 1.7 2 1 0 2 2 2 1 NUDIX domain NUDIX_4 PF14815.6 KFX92915.1 - 0.14 12.2 0.3 45 4.1 0.0 3.0 2 1 1 3 3 3 0 NUDIX domain Glyco_hydro_75 PF07335.11 KFX92917.1 - 3e-60 203.2 0.3 4.5e-60 202.6 0.3 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CarbpepA_inh PF02977.15 KFX92917.1 - 0.12 12.2 25.6 3.6 7.4 11.4 3.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Phage_tail_T PF06223.12 KFX92919.1 - 0.18 12.4 1.5 3.1 8.4 0.2 2.4 1 1 1 2 2 2 0 Minor tail protein T UPF0016 PF01169.19 KFX92919.1 - 0.33 11.3 18.2 5 7.5 2.4 3.2 1 1 3 4 4 4 0 Uncharacterized protein family UPF0016 BBP1_C PF15272.6 KFX92920.1 - 0.12 12.1 1.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Acyl-CoA_dh_1 PF00441.24 KFX92921.1 - 6.5e-43 146.5 1.4 6.5e-43 146.5 1.4 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX92921.1 - 5.9e-31 107.5 0.2 1.8e-30 105.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX92921.1 - 1.2e-27 96.0 0.2 2.5e-27 94.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX92921.1 - 1.3e-15 57.8 0.1 2.9e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFX92921.1 - 0.012 15.2 0.2 0.045 13.4 0.2 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 KFX92922.1 - 2.7e-136 455.1 0.1 3.5e-136 454.7 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Bot1p PF12298.8 KFX92923.1 - 1.4e-50 171.9 1.5 1.9e-50 171.4 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein TnsD PF15978.5 KFX92923.1 - 0.014 14.4 0.2 0.075 12.0 0.0 1.9 2 0 0 2 2 2 0 Tn7-like transposition protein D HTH_ParB PF17762.1 KFX92923.1 - 0.015 15.1 0.7 0.026 14.3 0.0 1.8 2 0 0 2 2 2 0 HTH domain found in ParB protein E1-E2_ATPase PF00122.20 KFX92924.1 - 1.2e-36 125.9 22.6 1.1e-31 109.7 0.4 4.0 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFX92924.1 - 2e-24 86.3 9.0 2e-24 86.3 9.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX92924.1 - 6e-19 69.2 0.0 1.4e-17 64.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX92924.1 - 2.2e-16 59.7 0.0 1.4e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX92924.1 - 9.1e-15 54.1 0.0 2.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX92924.1 - 0.00038 20.3 0.5 0.00088 19.1 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ytp1 PF10355.9 KFX92925.1 - 2.6e-97 325.3 10.3 5e-97 324.4 10.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFX92925.1 - 8.4e-26 89.8 7.6 1.7e-24 85.6 1.9 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) Zn_clus PF00172.18 KFX92925.1 - 5.4e-08 32.8 15.3 9.8e-08 32.0 15.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX92925.1 - 0.0012 17.7 0.0 0.0031 16.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Inhibitor_I66 PF16850.5 KFX92926.1 - 0.00064 19.6 0.1 0.0024 17.7 0.1 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I66 LNS2 PF08235.13 KFX92934.1 - 4.2e-94 314.2 0.0 5.9e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFX92934.1 - 6.6e-43 144.8 0.0 1.4e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KFX92934.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M49 PF03571.15 KFX92935.1 - 3.7e-213 708.9 0.0 4.6e-213 708.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.20 KFX92935.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CdiA_C_tRNase PF18664.1 KFX92935.1 - 0.16 12.2 0.0 0.81 9.9 0.0 2.0 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain HATPase_c_2 PF13581.6 KFX92936.1 - 0.044 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain 4HBT_3 PF13622.6 KFX92938.1 - 6.1e-40 138.0 0.0 9e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 KFX92938.1 - 1e-31 110.2 28.9 1e-31 110.2 28.9 1.9 3 0 0 3 3 3 1 Major Facilitator Superfamily 4HBT PF03061.22 KFX92938.1 - 0.00024 21.4 0.0 0.0022 18.3 0.1 2.2 2 0 0 2 2 2 1 Thioesterase superfamily Zn_clus PF00172.18 KFX92939.1 - 1.6e-06 28.1 8.5 3.2e-06 27.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ActA PF05058.12 KFX92939.1 - 0.1 10.9 0.1 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 ActA Protein PEP_mutase PF13714.6 KFX92940.1 - 8.8e-47 159.6 0.3 1.1e-46 159.3 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFX92940.1 - 2.9e-20 72.3 0.2 3.9e-20 71.8 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Harakiri PF15196.6 KFX92940.1 - 0.11 13.0 0.3 0.42 11.1 0.1 2.0 2 0 0 2 2 2 0 Activator of apoptosis harakiri RNA_pol_Rpb1_5 PF04998.17 KFX92943.1 - 2.7e-105 351.6 0.1 4.1e-105 351.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KFX92943.1 - 1.9e-104 349.4 0.0 3e-104 348.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFX92943.1 - 5.5e-77 257.7 0.0 1e-76 256.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KFX92943.1 - 3.6e-64 216.1 6.2 6.4e-64 215.3 6.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KFX92943.1 - 6.5e-48 162.2 4.1 4.9e-47 159.3 5.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KFX92943.1 - 6.9e-48 162.5 0.0 1.9e-47 161.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFX92943.1 - 2e-37 127.4 0.1 4.8e-37 126.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KFX92943.1 - 1.1e-11 44.5 174.4 0.029 14.7 3.1 12.7 9 1 7 16 16 16 14 RNA polymerase Rpb1 C-terminal repeat Pirin PF02678.16 KFX92944.1 - 8.9e-23 80.3 0.5 2.3e-22 79.0 0.5 1.7 1 0 0 1 1 1 1 Pirin ADH_zinc_N_2 PF13602.6 KFX92944.1 - 5.3e-10 40.5 0.0 1.9e-09 38.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX92944.1 - 2.2e-09 37.1 0.3 8.5e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 KFX92944.1 - 2.1e-05 24.2 4.0 8.1e-05 22.3 0.7 3.1 2 1 0 2 2 2 1 Cupin domain ADH_zinc_N PF00107.26 KFX92944.1 - 0.0001 22.3 0.4 0.0002 21.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Hemerythrin PF01814.23 KFX92945.1 - 9e-10 39.3 0.1 1.5e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain YnfE PF17452.2 KFX92945.1 - 0.079 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized YnfE-like Lactonase PF10282.9 KFX92946.1 - 3.9e-06 26.3 0.1 0.00053 19.4 0.0 2.8 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PQQ PF01011.21 KFX92946.1 - 0.13 12.2 0.7 3 7.9 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1815 PF08844.10 KFX92946.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) bZIP_1 PF00170.21 KFX92947.1 - 6.1e-06 26.2 6.5 6.1e-06 26.2 6.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX92947.1 - 6.7 6.9 12.1 0.79 9.9 7.6 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Annexin PF00191.20 KFX92948.1 - 1.3e-18 66.8 3.8 0.00043 20.3 0.0 4.3 4 0 0 4 4 4 4 Annexin GPI2 PF06432.11 KFX92949.1 - 2.2e-135 450.5 0.2 2.6e-135 450.3 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.8 KFX92949.1 - 0.063 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) FMO-like PF00743.19 KFX92950.1 - 1.2e-16 60.2 0.3 9.7e-16 57.3 0.3 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX92950.1 - 2.1e-11 43.6 0.3 4.4e-08 32.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX92950.1 - 1.4e-08 34.4 0.0 1.5e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX92950.1 - 2.9e-08 33.3 0.0 3.4e-05 23.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX92950.1 - 7.7e-07 29.2 0.0 2.3e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX92950.1 - 2.4e-05 24.1 0.0 0.00078 19.1 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFX92950.1 - 0.0001 22.4 0.1 0.06 13.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFX92950.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFX92950.1 - 0.056 12.7 0.8 0.086 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KFX92950.1 - 0.11 12.5 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX92950.1 - 0.11 11.2 0.5 0.24 10.1 0.5 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KFX92950.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 KFX92951.1 - 1.4e-19 70.2 2.3 1.8e-19 69.8 1.6 1.6 2 0 0 2 2 2 1 FAD binding domain p450 PF00067.22 KFX92952.1 - 1.7e-19 70.0 0.0 2e-14 53.2 0.0 2.9 1 1 2 3 3 3 3 Cytochrome P450 Glyco_hydro_7 PF00840.20 KFX92953.1 - 3.7e-192 638.8 10.5 5.5e-192 638.3 10.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pec_lyase_C PF00544.19 KFX92953.1 - 1.4e-16 60.8 6.9 4.5e-15 55.8 6.9 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX92953.1 - 1e-07 32.0 10.5 5.1e-07 29.7 7.9 2.0 1 1 1 2 2 2 2 Right handed beta helix region Cu-oxidase_3 PF07732.15 KFX92954.1 - 1.4e-11 44.4 0.1 5.2e-08 32.9 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX92954.1 - 1.5e-09 37.7 0.0 0.005 16.6 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KFX92954.1 - 0.019 15.1 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 Cupredoxin-like domain Copper-bind PF00127.20 KFX92954.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family SGL PF08450.12 KFX92955.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Abhydrolase_3 PF07859.13 KFX92956.1 - 2.5e-34 119.0 0.1 4.5e-34 118.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX92956.1 - 1.6e-05 24.0 0.0 0.00014 20.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFX92956.1 - 0.0028 17.2 0.2 0.0051 16.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KFX92956.1 - 0.0072 15.0 0.1 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KFX92956.1 - 0.0097 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KFX92956.1 - 0.017 14.6 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 KFX92956.1 - 0.062 12.8 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFX92956.1 - 0.3 11.7 3.8 0.92 10.1 3.9 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sortilin-Vps10 PF15902.5 KFX92957.1 - 2.3e-22 79.4 0.8 1.6e-08 33.8 0.0 5.7 4 2 2 6 6 6 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFX92957.1 - 3.9e-10 38.2 39.4 0.26 11.5 0.5 9.4 9 0 0 9 9 9 8 BNR/Asp-box repeat BNR_6 PF15899.5 KFX92957.1 - 4.5e-05 23.1 24.2 0.16 12.1 0.1 9.1 10 0 0 10 10 10 1 BNR-Asp box repeat UCR_UQCRX_QCR9 PF05365.12 KFX92957.1 - 0.85 9.6 4.8 23 5.0 0.0 3.6 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro2_C5 PF18565.1 KFX92958.1 - 3e-33 113.8 0.2 5.1e-33 113.0 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 KFX92958.1 - 3.3e-24 84.6 0.2 1.1e-23 82.9 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_C PF02836.17 KFX92958.1 - 1.1e-23 83.9 0.0 2.9e-23 82.4 0.0 1.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFX92958.1 - 9.5e-16 58.2 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFX92958.1 - 7.4e-13 49.1 0.3 1.7e-12 48.0 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFX92958.1 - 0.00092 19.8 0.0 0.0067 17.0 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KFX92958.1 - 1.1 9.6 9.6 0.15 12.4 1.3 3.2 3 1 0 3 3 3 0 Invasin, domain 3 fn3 PF00041.21 KFX92959.1 - 2.7e-07 30.8 0.0 8.5e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Fez1 PF06818.15 KFX92959.1 - 4.8 7.6 36.9 8.5 6.8 4.0 2.4 2 0 0 2 2 2 0 Fez1 DAO PF01266.24 KFX92966.1 - 1.1e-51 176.5 0.0 1.9e-51 175.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFX92966.1 - 5e-45 152.4 0.1 1.1e-44 151.3 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase PPR_2 PF13041.6 KFX92966.1 - 5.3e-18 64.9 0.0 1.6e-08 34.6 0.0 4.5 4 1 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KFX92966.1 - 1.3e-10 41.2 0.0 2.5e-06 27.5 0.0 3.9 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KFX92966.1 - 7.5e-10 38.4 0.0 0.013 15.7 0.0 5.0 5 0 0 5 5 5 2 PPR repeat FAD_binding_2 PF00890.24 KFX92966.1 - 1.6e-08 34.1 0.2 3.6e-08 32.9 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain PPR_long PF17177.4 KFX92966.1 - 6.7e-07 28.9 0.0 0.018 14.4 0.0 3.6 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFX92966.1 - 5.3e-06 26.0 0.0 0.3 10.8 0.0 4.3 4 0 0 4 4 4 2 PPR repeat FAD_oxidored PF12831.7 KFX92966.1 - 0.00012 21.5 0.1 0.00059 19.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX92966.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX92966.1 - 0.0037 17.5 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX92966.1 - 0.065 11.9 0.2 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFX92966.1 - 0.07 12.4 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX92966.1 - 0.076 13.6 0.3 0.21 12.1 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX92966.1 - 0.23 10.7 0.4 0.55 9.4 0.4 1.6 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KFX92966.1 - 0.27 10.2 0.5 0.8 8.7 0.4 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A cwf18 PF08315.12 KFX92967.1 - 4.7e-46 156.8 6.8 4.7e-46 156.8 6.8 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 KFX92968.1 - 4.9e-20 71.2 1.8 1.2e-19 70.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFX92968.1 - 0.018 14.7 0.4 0.045 13.5 0.4 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KFX92968.1 - 0.18 12.0 1.3 0.29 11.3 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.7 KFX92969.1 - 2e-17 63.7 1.8 2e-17 63.7 1.8 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 KFX92969.1 - 1.2e-08 34.8 0.1 2.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.19 KFX92970.1 - 2.7e-33 114.7 0.0 5.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KFX92970.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain DUF3552 PF12072.8 KFX92970.1 - 0.39 10.1 3.8 1.4 8.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) AIM5 PF17050.5 KFX92971.1 - 4.3e-18 65.9 1.1 4.3e-18 65.9 1.1 3.0 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 MarR_2 PF12802.7 KFX92971.1 - 1.6 8.7 5.0 18 5.3 0.2 3.8 3 1 1 4 4 4 0 MarR family UTP25 PF06862.12 KFX92972.1 - 3.7e-202 672.3 0.2 4.3e-202 672.0 0.2 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KFX92972.1 - 1.4e-05 24.9 0.0 0.00038 20.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Nop14 PF04147.12 KFX92972.1 - 1.2 7.3 15.5 2.4 6.3 15.5 1.4 1 0 0 1 1 1 0 Nop14-like family DUF3347 PF11827.8 KFX92972.1 - 9 6.4 7.1 14 5.8 4.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3347) JAB PF01398.21 KFX92973.1 - 1.8e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFX92973.1 - 3.7e-18 66.0 0.3 6.3e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KFX92973.1 - 0.079 13.0 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF3113 PF11310.8 KFX92973.1 - 0.099 12.6 0.1 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Ribosom_S12_S23 PF00164.25 KFX92975.1 - 1.1e-50 170.0 0.7 1.5e-50 169.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KFX92976.1 - 2.1e-24 85.1 1.7 4.6e-24 84.0 1.7 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) DUF1242 PF06842.12 KFX92977.1 - 1.3e-16 60.1 0.1 2.9e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 KFX92978.1 - 7.3e-18 64.4 0.0 2e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit BTB PF00651.31 KFX92978.1 - 5.3e-08 33.1 0.0 1.8e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Bromo_TP PF07524.13 KFX92978.1 - 0.065 13.3 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated NitrOD5 PF11537.8 KFX92978.1 - 0.14 12.3 0.0 0.53 10.4 0.0 1.9 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 4HBT_2 PF13279.6 KFX92981.1 - 9.3e-05 22.9 0.0 0.0001 22.8 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 KFX92991.1 - 1.1e-41 143.0 56.0 1.2e-41 142.8 53.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX92991.1 - 2.2e-15 56.1 20.2 3.8e-15 55.3 20.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 KFX92992.1 - 1.5e-45 152.2 17.8 1.4e-08 35.3 0.0 7.8 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX92992.1 - 1.1e-21 76.9 0.0 0.0013 19.0 0.0 7.0 1 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX92992.1 - 2.5e-16 59.1 1.8 0.39 10.7 0.0 7.5 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX92992.1 - 4.8e-13 48.8 2.1 0.0068 15.4 0.0 6.3 3 2 3 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX92992.1 - 4e-09 36.6 0.0 3.7e-05 23.7 0.0 2.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 KFX92992.1 - 8.6e-08 31.7 5.5 5.9 6.7 0.0 8.0 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 KFX92992.1 - 0.001 18.5 2.6 2.8 7.2 0.0 5.2 2 2 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal Zn_clus PF00172.18 KFX92992.1 - 0.0039 17.3 15.1 0.0077 16.3 15.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.8 KFX92992.1 - 0.0051 15.5 0.1 0.096 11.3 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 KFX92992.1 - 0.0051 15.9 0.0 1.5 7.8 0.0 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) DPPIV_N PF00930.21 KFX92992.1 - 0.0083 14.9 0.0 0.91 8.2 0.0 3.2 3 1 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region RAB3GAP2_N PF14655.6 KFX92992.1 - 0.027 13.7 0.0 8 5.6 0.0 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 KFX92992.1 - 0.069 11.7 0.0 2.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Beta-lactamase PF00144.24 KFX92993.1 - 1.3e-43 149.5 0.0 1.9e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Herpes_UL56 PF04534.12 KFX92996.1 - 0.058 12.9 0.7 0.062 12.8 0.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL56 protein NACHT PF05729.12 KFX92997.1 - 2.6e-08 34.0 0.7 1.3e-07 31.7 0.3 2.5 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFX92997.1 - 0.00014 22.1 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX92997.1 - 0.00018 21.9 3.1 0.00024 21.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFX92997.1 - 0.0063 17.1 0.4 0.055 14.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFX92997.1 - 0.019 15.3 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 KFX92997.1 - 0.026 14.6 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KFX92997.1 - 0.051 13.3 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KFX92997.1 - 0.051 13.3 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KFX92997.1 - 0.13 12.1 0.1 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KFX92997.1 - 0.67 10.5 0.0 0.67 10.5 0.0 3.2 3 1 0 3 3 3 0 ABC transporter Slu7 PF11708.8 KFX92997.1 - 9.3 5.9 13.8 9.1 5.9 7.5 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor SAM_2 PF07647.17 KFX93014.1 - 1.2e-09 38.1 0.0 3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_1 PF00170.21 KFX93014.1 - 0.00018 21.5 3.1 0.00018 21.5 3.1 3.0 3 0 0 3 3 3 1 bZIP transcription factor SAM_1 PF00536.30 KFX93014.1 - 0.0036 17.7 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_2 PF07716.15 KFX93014.1 - 0.004 17.2 5.1 0.004 17.2 5.1 3.0 3 0 0 3 3 3 1 Basic region leucine zipper Tugs PF17840.1 KFX93014.1 - 0.12 12.6 0.1 0.49 10.6 0.1 2.1 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF846 PF05832.12 KFX93015.1 - 2.2e-50 170.3 13.8 2.5e-50 170.1 13.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 KFX93015.1 - 2.5 8.2 10.6 0.19 11.8 3.5 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5504) adh_short PF00106.25 KFX93017.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Med14 PF08638.11 KFX93018.1 - 3e-64 216.0 0.0 5.7e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.8 KFX93019.1 - 1.2e-186 621.0 12.7 1.4e-186 620.8 12.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KFX93019.1 - 0.00041 19.4 9.7 0.00041 19.4 9.7 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily Pex24p PF06398.11 KFX93019.1 - 1.2 8.0 10.2 1.9 7.4 6.8 2.6 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Fungal_trans PF04082.18 KFX93036.1 - 1.5e-44 152.0 0.1 5.3e-44 150.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93036.1 - 1.3e-08 34.8 8.1 2.7e-08 33.8 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 KFX93037.1 - 1.7e-28 99.9 0.7 2.5e-28 99.3 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nipped-B_C PF12830.7 KFX93038.1 - 1.9e-48 165.0 11.3 8.3e-48 162.9 3.3 3.3 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFX93038.1 - 3.1e-05 24.2 1.2 7.7e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KFX93038.1 - 0.00096 19.2 3.1 0.0013 18.8 0.1 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX93038.1 - 0.028 14.7 7.5 19 5.8 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 KFX93038.1 - 0.029 14.8 2.9 0.91 10.0 1.5 4.1 2 1 1 3 3 3 0 HEAT repeats AAA_lid_7 PF17867.1 KFX93038.1 - 0.072 13.3 0.1 0.47 10.7 0.1 2.5 1 0 0 1 1 1 0 Midasin AAA lid domain Exo70 PF03081.15 KFX93038.1 - 0.11 11.5 1.9 0.34 9.9 1.0 2.3 3 0 0 3 3 3 0 Exo70 exocyst complex subunit TFIIS_C PF01096.18 KFX93039.1 - 3.4e-14 52.4 1.9 3.4e-14 52.4 1.9 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFX93039.1 - 3.2e-05 23.7 2.1 3.2e-05 23.7 2.1 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 KFX93039.1 - 0.0026 17.4 11.8 1.9 8.3 0.1 4.0 4 0 0 4 4 4 3 zinc-ribbon domain zf-RING_7 PF02591.15 KFX93039.1 - 0.013 15.7 5.7 0.21 11.8 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain RecR PF02132.15 KFX93039.1 - 0.028 14.0 2.1 0.028 14.0 2.1 2.2 2 0 0 2 2 2 0 RecR protein GcpE PF04551.14 KFX93039.1 - 0.086 11.9 0.4 0.11 11.6 0.4 1.3 1 1 0 1 1 1 0 GcpE protein DUF3797 PF12677.7 KFX93039.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3797) OrfB_Zn_ribbon PF07282.11 KFX93039.1 - 0.17 11.9 12.2 0.44 10.5 0.8 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KFX93039.1 - 0.34 11.1 0.1 0.34 11.1 0.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain UPF0547 PF10571.9 KFX93039.1 - 0.58 10.3 17.4 0.71 10.0 0.3 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Ribosomal_S27e PF01667.17 KFX93039.1 - 0.82 9.4 7.3 31 4.4 0.1 3.2 2 1 0 2 2 2 0 Ribosomal protein S27 DZR PF12773.7 KFX93039.1 - 1.1 9.4 14.3 1.5 9.0 3.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFX93039.1 - 1.1 8.8 12.6 1 8.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KFX93039.1 - 1.4 8.9 11.2 1.2 9.1 2.7 3.1 3 0 0 3 3 3 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 KFX93039.1 - 1.5 8.4 15.9 0.87 9.2 1.0 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding DUF2072 PF09845.9 KFX93039.1 - 1.8 8.8 7.8 7.5 6.8 0.3 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein zf-IS66 PF13005.7 KFX93039.1 - 1.8 9.0 12.6 13 6.2 0.1 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KFX93039.1 - 5.8 7.4 11.9 7.5 7.0 1.5 3.1 2 2 0 2 2 2 0 Restriction alleviation protein Lar HEAT_2 PF13646.6 KFX93040.1 - 5.1e-27 94.1 10.0 2.3e-14 53.5 0.2 3.4 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KFX93040.1 - 6.4e-20 69.8 6.6 0.00091 19.7 0.2 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KFX93040.1 - 8.2e-07 28.8 5.2 0.11 12.8 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KFX93040.1 - 0.00012 22.5 7.6 0.12 12.9 0.6 4.9 4 1 0 4 4 4 2 HEAT-like repeat ERAP1_C PF11838.8 KFX93040.1 - 0.073 12.6 0.6 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Cohesin_HEAT PF12765.7 KFX93040.1 - 0.082 13.2 0.3 0.68 10.3 0.0 2.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KFX93040.1 - 0.15 12.1 0.0 1.8 8.6 0.0 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.27 KFX93041.1 - 2.1e-47 161.1 0.1 3.5e-23 82.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KFX93041.1 - 1.5e-29 101.9 1.3 3.6e-29 100.6 0.2 2.4 2 0 0 2 2 1 1 Four helical bundle domain SMC_N PF02463.19 KFX93041.1 - 4.6e-18 65.5 0.0 1.6e-06 27.7 0.2 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX93041.1 - 3.6e-17 63.1 0.2 0.002 18.0 0.0 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX93041.1 - 1.4e-10 42.1 3.6 0.0001 22.9 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFX93041.1 - 1.3e-08 34.4 0.1 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX93041.1 - 2.5e-08 34.0 0.0 0.00037 20.5 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX93041.1 - 1.7e-07 31.3 0.0 0.0014 18.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KFX93041.1 - 4.3e-07 30.3 0.1 0.0063 16.8 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.6 KFX93041.1 - 7.8e-07 29.5 0.1 0.016 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KFX93041.1 - 9.4e-07 29.0 0.0 0.00032 20.8 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 KFX93041.1 - 5.7e-06 26.9 0.1 0.11 13.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFX93041.1 - 1.8e-05 24.9 0.2 0.43 10.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KFX93041.1 - 6e-05 23.4 0.0 0.84 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KFX93041.1 - 8.1e-05 23.1 0.0 0.46 10.9 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KFX93041.1 - 9.9e-05 21.4 0.1 0.36 9.8 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KFX93041.1 - 0.00011 22.0 5.1 0.048 13.4 0.0 3.7 4 1 0 5 5 4 2 AAA ATPase domain AAA_16 PF13191.6 KFX93041.1 - 0.00013 22.4 1.0 0.56 10.6 0.0 3.6 5 0 0 5 5 2 2 AAA ATPase domain AAA_27 PF13514.6 KFX93041.1 - 0.00019 21.1 0.0 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX93041.1 - 0.00073 19.3 0.1 1.4 8.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KFX93041.1 - 0.00074 19.5 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 KFX93041.1 - 0.00075 19.3 0.0 0.66 9.7 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KFX93041.1 - 0.00094 19.0 0.0 2.4 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KFX93041.1 - 0.0014 18.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFX93041.1 - 0.0018 18.3 0.0 2.9 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KFX93041.1 - 0.0027 16.9 0.2 2.2 7.3 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit DUF87 PF01935.17 KFX93041.1 - 0.0028 17.8 1.9 1.1 9.3 0.1 3.5 3 0 0 3 3 3 1 Helicase HerA, central domain cobW PF02492.19 KFX93041.1 - 0.0042 16.7 0.2 2.9 7.5 0.0 3.2 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KFX93041.1 - 0.0059 16.8 0.2 10 6.4 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KFX93041.1 - 0.0098 15.8 0.0 3 7.7 0.0 3.3 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KFX93041.1 - 0.017 14.9 0.2 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KFX93041.1 - 0.018 14.2 1.7 0.35 10.0 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain CLP1_P PF16575.5 KFX93041.1 - 0.019 14.7 0.0 0.87 9.3 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 KFX93041.1 - 0.019 14.7 0.0 4.9 6.8 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX93041.1 - 0.019 14.5 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KFX93041.1 - 0.02 15.1 0.0 5.5 7.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KFX93041.1 - 0.029 14.1 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 KFX93041.1 - 0.037 13.7 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KFX93041.1 - 0.039 13.2 0.0 5.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.21 KFX93041.1 - 0.04 13.3 0.1 4 6.8 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KFX93041.1 - 0.046 13.6 0.2 10 6.0 0.1 2.8 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KFX93041.1 - 0.05 13.3 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase MukB PF04310.12 KFX93041.1 - 0.059 13.2 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.6 KFX93041.1 - 0.063 12.9 0.0 13 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF1889 PF08986.10 KFX93041.1 - 0.11 12.9 0.1 0.51 10.7 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF1889) T2SSE PF00437.20 KFX93041.1 - 0.12 11.4 1.7 7.8 5.5 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein FeoB_N PF02421.18 KFX93041.1 - 0.13 11.8 0.2 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 KFX93041.1 - 0.14 12.1 0.2 26 4.8 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KFX93041.1 - 1 7.9 11.5 1.6 7.3 0.0 4.3 5 0 0 5 5 4 0 AAA domain DAP3 PF10236.9 KFX93041.1 - 2.3 7.3 5.9 13 4.9 1.2 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 V-ATPase_H_C PF11698.8 KFX93041.1 - 3.1 7.9 4.8 1.9 8.6 1.8 2.2 2 0 0 2 2 1 0 V-ATPase subunit H RTA1 PF04479.13 KFX93044.1 - 1.7e-44 151.9 2.3 1.7e-44 151.9 2.3 1.4 1 1 0 1 1 1 1 RTA1 like protein PAP2_C PF14360.6 KFX93044.1 - 0.081 13.5 2.6 0.41 11.2 2.6 2.3 1 0 0 1 1 1 0 PAP2 superfamily C-terminal TM231 PF10149.9 KFX93044.1 - 0.37 10.1 2.1 0.57 9.5 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 DUF308 PF03729.13 KFX93044.1 - 0.68 10.3 10.2 0.23 11.8 1.3 3.2 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Arginase PF00491.21 KFX93045.1 - 7.8e-72 242.1 0.9 9e-72 241.9 0.9 1.0 1 0 0 1 1 1 1 Arginase family HCO3_cotransp PF00955.21 KFX93058.1 - 2.5e-70 237.7 15.1 3.1e-38 131.9 8.7 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF948 PF06103.11 KFX93058.1 - 0.32 11.3 0.7 0.85 9.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tnp_DNA_bind PF14706.6 KFX93059.1 - 0.065 13.1 0.3 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Transposase DNA-binding Spc7 PF08317.11 KFX93074.1 - 0.043 12.7 2.5 2.3 7.0 1.1 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Metallophos PF00149.28 KFX93078.1 - 5.8e-13 49.8 0.0 8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX93078.1 - 4.7e-07 30.2 0.2 1.5e-06 28.5 0.2 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Isy1 PF06246.12 KFX93079.1 - 2.7e-71 240.1 0.5 3.3e-71 239.8 0.5 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Methyltransf_2 PF00891.18 KFX93081.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KFX93081.1 - 0.049 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Abhydrolase_1 PF00561.20 KFX93082.1 - 2.8e-17 63.2 0.0 3.2e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX93082.1 - 6.3e-17 62.9 9.0 1.2e-15 58.7 9.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.28 KFX93082.1 - 6.2e-15 55.4 0.0 1.5e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Hydrolase_4 PF12146.8 KFX93082.1 - 1.6e-13 50.5 0.0 3.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KFX93082.1 - 0.043 13.4 0.0 7.3 6.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KFX93082.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Sugar_tr PF00083.24 KFX93083.1 - 1.9e-109 366.6 19.4 2.2e-109 366.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93083.1 - 6.2e-24 84.6 26.7 1.3e-15 57.2 5.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX93083.1 - 3.6e-05 22.5 18.2 0.00039 19.1 7.2 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein DUF21 PF01595.20 KFX93083.1 - 2 8.1 5.4 1.7 8.3 3.0 2.0 1 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain ACT_3 PF10000.9 KFX93084.1 - 6.7e-20 70.8 1.4 4.7e-19 68.1 0.7 2.3 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 KFX93084.1 - 4e-12 45.7 0.1 8.6e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain Abhydrolase_1 PF00561.20 KFX93090.1 - 1.3e-42 146.2 0.1 1.9e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFX93090.1 - 8.5e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 KFX93090.1 - 0.033 14.1 1.0 0.075 12.9 1.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein NuiA PF07924.11 KFX93100.1 - 0.003 17.9 0.0 0.19 12.1 0.0 2.2 1 1 1 2 2 2 2 Nuclease A inhibitor-like protein Exo70 PF03081.15 KFX93101.1 - 4.6e-84 282.6 0.0 1.3e-83 281.2 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Reticulon PF02453.17 KFX93102.1 - 1.9e-28 99.4 1.2 2.7e-28 98.9 1.2 1.2 1 0 0 1 1 1 1 Reticulon FlgN PF05130.12 KFX93102.1 - 0.17 12.4 0.8 0.29 11.6 0.1 1.7 2 0 0 2 2 2 0 FlgN protein Aminotran_1_2 PF00155.21 KFX93103.1 - 5.9e-44 150.7 0.0 6.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFX93103.1 - 0.033 13.1 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Allinase GATA PF00320.27 KFX93106.1 - 1.3e-16 59.9 2.7 7.8e-16 57.4 2.5 2.3 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.10 KFX93106.1 - 5.7e-13 48.4 2.8 1.1e-12 47.5 2.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SRF-TF PF00319.18 KFX93108.1 - 7.1e-21 73.4 0.1 1e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) F-box-like PF12937.7 KFX93111.1 - 2.8e-10 39.9 0.3 7.3e-10 38.6 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX93111.1 - 0.00023 20.9 0.4 0.00074 19.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KFX93111.1 - 0.0053 17.1 1.9 8.3 7.0 0.4 4.0 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) Glyco_hydro_3_C PF01915.22 KFX93115.1 - 1e-53 182.4 0.1 2e-53 181.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX93115.1 - 5.1e-40 137.8 0.0 7.7e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_88 PF07470.13 KFX93115.1 - 3.5e-29 102.0 0.0 8.2e-29 100.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fn3-like PF14310.6 KFX93115.1 - 8.4e-28 96.3 0.1 1.6e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3372 PF11852.8 KFX93115.1 - 0.047 13.2 0.2 0.096 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Stb3 PF10330.9 KFX93115.1 - 0.14 12.2 0.1 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative Sin3 binding protein Toxin_8 PF07365.12 KFX93115.1 - 0.91 9.8 6.2 1.9 8.7 1.5 2.7 2 0 0 2 2 2 0 Alpha conotoxin precursor SCO1-SenC PF02630.14 KFX93116.1 - 3.2e-48 163.0 0.0 5.5e-48 162.3 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFX93116.1 - 0.00013 21.8 0.0 0.00059 19.8 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family HemY_N PF07219.13 KFX93116.1 - 0.063 13.5 10.4 1.6 9.0 1.9 3.0 2 0 0 2 2 2 0 HemY protein N-terminus SIP1 PF04938.12 KFX93118.1 - 8.8e-13 48.5 0.0 6.3e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PTPRCAP PF15713.5 KFX93118.1 - 4 7.7 14.0 6.2 7.1 3.9 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated LIAS_N PF16881.5 KFX93119.1 - 7.4e-15 55.3 0.0 1.6e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFX93119.1 - 2.7e-13 50.6 0.0 6.5e-13 49.4 0.0 1.6 1 1 1 2 2 2 1 Radical SAM superfamily zf-RING_2 PF13639.6 KFX93127.1 - 1.8e-10 40.9 4.5 3.7e-10 40.0 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFX93127.1 - 1.5e-08 34.7 4.4 3.3e-08 33.7 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFX93127.1 - 4.9e-06 26.5 0.5 9.5e-06 25.6 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFX93127.1 - 1.9e-05 24.4 1.9 3.5e-05 23.6 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX93127.1 - 4.7e-05 23.1 3.8 9.1e-05 22.2 3.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFX93127.1 - 7.5e-05 22.5 6.3 0.00023 20.9 6.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX93127.1 - 8.8e-05 22.4 3.3 0.00015 21.6 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFX93127.1 - 9.7e-05 22.2 4.2 0.00017 21.4 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX93127.1 - 0.0028 17.6 4.6 0.0067 16.4 4.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KFX93127.1 - 0.0034 17.5 5.8 0.056 13.6 5.8 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 KFX93127.1 - 0.01 15.5 2.1 0.025 14.3 2.1 1.7 1 1 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 KFX93127.1 - 0.051 13.2 1.3 0.13 11.9 1.3 1.7 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KFX93127.1 - 0.092 12.4 1.7 0.19 11.4 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3533 PF12051.8 KFX93127.1 - 0.64 8.9 2.6 0.94 8.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Inhibitor_I9 PF05922.16 KFX93130.1 - 0.005 17.5 0.1 0.0055 17.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 CFIA_Pcf11 PF11526.8 KFX93131.1 - 4.3e-09 36.7 0.4 1.1e-08 35.4 0.4 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KFX93131.1 - 1.5e-05 25.7 0.0 4.7e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 KFX93131.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain zf-C2H2_4 PF13894.6 KFX93131.1 - 0.89 10.6 3.4 10 7.3 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFX93131.1 - 0.99 9.1 8.3 1.3 8.7 3.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF3435 PF11917.8 KFX93134.1 - 1.5e-56 192.1 0.0 2e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo_2 PF18704.1 KFX93134.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 Mito_carr PF00153.27 KFX93136.1 - 5.7e-55 183.2 7.0 1.6e-18 66.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 KFX93138.1 - 6.3e-47 159.9 2.0 8.5e-47 159.5 2.0 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KFX93138.1 - 6.1 6.0 36.3 0.036 13.3 17.2 2.9 1 1 1 2 2 2 0 ZIP Zinc transporter Glyco_trans_1_4 PF13692.6 KFX93139.1 - 1.9e-06 28.3 0.0 3.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFX93139.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_12 PF13424.6 KFX93148.1 - 7.8e-62 205.5 43.7 3.2e-11 43.4 0.3 12.1 8 1 6 14 14 14 13 Tetratricopeptide repeat TPR_10 PF13374.6 KFX93148.1 - 3.7e-39 131.5 34.6 5.3e-05 22.9 0.7 16.2 17 0 0 17 17 16 9 Tetratricopeptide repeat Ank_2 PF12796.7 KFX93148.1 - 1.4e-33 115.3 1.5 1.4e-09 38.4 0.0 8.1 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX93148.1 - 5.9e-21 72.3 17.3 0.0089 16.5 0.1 11.9 12 0 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.6 KFX93148.1 - 2.7e-20 72.5 3.0 2.7e-05 24.6 0.0 8.1 5 2 4 9 9 9 4 Ankyrin repeats (many copies) Pkinase PF00069.25 KFX93148.1 - 6.4e-20 71.6 0.0 1.4e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 KFX93148.1 - 9.2e-20 70.1 19.7 0.0031 17.9 0.0 11.4 12 0 0 12 12 11 4 Ankyrin repeat Pkinase_Tyr PF07714.17 KFX93148.1 - 8.4e-19 67.9 0.0 1.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KFX93148.1 - 5.8e-14 52.0 6.5 0.0072 16.6 0.0 8.7 8 1 1 9 9 9 2 Ankyrin repeats (many copies) TPR_7 PF13176.6 KFX93148.1 - 3.9e-06 26.5 17.9 0.096 12.8 0.2 9.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX93148.1 - 2.7e-05 23.7 25.0 0.12 11.7 4.3 4.5 2 1 1 4 4 4 3 MalT-like TPR region TPR_19 PF14559.6 KFX93148.1 - 0.00021 21.8 16.4 0.13 12.8 0.0 8.2 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93148.1 - 0.01 15.6 26.4 1.6 8.7 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Sel1 PF08238.12 KFX93148.1 - 0.017 15.8 0.1 0.078 13.7 0.1 2.2 1 0 0 1 1 1 0 Sel1 repeat TPR_4 PF07721.14 KFX93148.1 - 0.04 14.5 0.2 17 6.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93148.1 - 0.041 14.0 33.0 2.7 8.3 0.1 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX93148.1 - 0.78 10.4 19.6 6.9 7.4 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF489 PF04356.12 KFX93148.1 - 2.5 8.1 7.7 0.7 9.9 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Glycogen_syn PF05693.13 KFX93150.1 - 0 1163.7 0.0 0 1163.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KFX93150.1 - 2.3e-06 27.7 0.1 5.5e-05 23.2 0.2 2.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFX93150.1 - 3.7e-05 24.2 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KFX93150.1 - 4.4e-05 23.3 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFX93150.1 - 6.5e-05 22.5 0.0 0.0033 17.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFX93150.1 - 0.00012 22.5 0.1 0.00039 20.9 0.1 2.0 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Sec5 PF15469.6 KFX93152.1 - 0.0098 15.7 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 zf-C3HC4 PF00097.25 KFX93153.1 - 4.6e-07 29.6 8.7 7.8e-07 28.9 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX93153.1 - 6.9e-06 25.8 6.4 4.9e-05 23.1 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX93153.1 - 1.1e-05 25.3 5.4 1.1e-05 25.3 5.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFX93153.1 - 1.9e-05 24.4 6.1 3.5e-05 23.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX93153.1 - 2.4e-05 24.4 7.6 4.8e-05 23.4 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX93153.1 - 2.6e-05 24.5 8.7 5.8e-05 23.3 8.7 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX93153.1 - 0.00012 22.0 6.4 0.00023 21.0 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX93153.1 - 0.0074 16.1 8.4 0.083 12.8 8.2 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFX93153.1 - 1.2 9.4 6.5 3.4 8.0 6.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFX93153.1 - 1.5 9.0 4.3 3.4 7.9 4.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 UCH PF00443.29 KFX93154.1 - 3e-47 161.3 0.0 6.1e-47 160.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX93154.1 - 2.8e-10 40.3 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SET PF00856.28 KFX93155.1 - 1.6e-10 41.6 0.0 1.9e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_19 PF14559.6 KFX93155.1 - 0.001 19.5 3.3 0.0088 16.5 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX93155.1 - 0.0056 16.9 0.2 0.014 15.6 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 KFX93155.1 - 0.05 13.6 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_2 PF07719.17 KFX93155.1 - 4.2 7.7 5.9 36 4.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat GFA PF04828.14 KFX93156.1 - 6.3e-08 32.9 1.5 0.00013 22.3 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme TFIID-18kDa PF02269.16 KFX93157.1 - 7.4e-31 106.0 0.9 3.1e-30 104.1 0.1 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KFX93157.1 - 0.039 14.1 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region LCM PF04072.14 KFX93158.1 - 2.3e-22 79.8 0.0 3.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3180 PF11377.8 KFX93164.1 - 0.021 15.0 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Ofd1_CTDD PF10637.9 KFX93168.1 - 1.3e-35 123.0 0.7 1.6e-35 122.7 0.7 1.1 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF1963 PF09234.10 KFX93168.1 - 0.033 14.6 0.1 0.044 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) CSRNP_N PF16019.5 KFX93168.1 - 0.061 13.2 0.4 0.092 12.7 0.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Limkain-b1 PF11608.8 KFX93168.1 - 0.16 12.1 0.3 0.31 11.2 0.3 1.4 1 0 0 1 1 1 0 Limkain b1 BUD22 PF09073.10 KFX93168.1 - 2.7 7.2 20.5 3.4 6.9 20.5 1.2 1 0 0 1 1 1 0 BUD22 AA_permease PF00324.21 KFX93169.1 - 7.2e-124 414.0 39.4 8.8e-124 413.7 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX93169.1 - 7.7e-37 127.1 42.0 1.1e-36 126.6 42.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4139 PF13598.6 KFX93170.1 - 0.081 12.6 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Ribosomal_S7 PF00177.21 KFX93173.1 - 1.9e-36 124.9 2.4 2.4e-36 124.6 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.15 KFX93174.1 - 2.5e-38 130.4 3.0 2.7e-38 130.2 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KFX93174.1 - 0.0029 17.5 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KFX93174.1 - 0.0073 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 KFX93174.1 - 0.013 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KFX93174.1 - 0.033 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Cyt-b5 PF00173.28 KFX93175.1 - 1.8e-10 40.8 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5504 PF17608.2 KFX93175.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DEAD PF00270.29 KFX93176.1 - 1.9e-34 119.0 0.8 1.7e-16 60.5 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX93176.1 - 1.8e-21 76.6 0.0 4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX93176.1 - 5.9e-05 23.1 0.0 0.00054 20.0 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIA PF03153.13 KFX93176.1 - 1.6 8.6 33.8 0.62 10.0 5.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PIGA PF08288.12 KFX93177.1 - 2.8e-46 156.0 5.0 3.4e-46 155.8 1.9 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KFX93177.1 - 3.9e-29 101.8 0.5 6.3e-29 101.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KFX93177.1 - 4.4e-26 91.4 0.0 6.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFX93177.1 - 4.1e-24 85.5 0.2 7.9e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFX93177.1 - 4.2e-12 46.8 0.0 1e-11 45.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KFX93177.1 - 3.8e-06 27.0 0.1 9.7e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KFX93177.1 - 0.00071 19.9 0.0 0.0027 18.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_hydro_10 PF00331.20 KFX93178.1 - 2.5e-103 345.5 0.0 2.9e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 FeS_assembly_P PF01883.19 KFX93178.1 - 0.066 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein NPR3 PF03666.13 KFX93179.1 - 6.7e-147 490.0 0.3 1.1e-146 489.3 0.1 1.4 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 CHCH PF06747.13 KFX93180.1 - 3.3e-05 23.9 0.5 6e-05 23.1 0.5 1.5 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KFX93180.1 - 0.0042 17.4 2.1 0.17 12.2 0.3 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KFX93180.1 - 0.018 15.3 2.6 0.12 12.7 2.9 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GFA PF04828.14 KFX93181.1 - 2.2e-07 31.1 1.0 5.1e-07 29.9 0.9 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4614 PF15391.6 KFX93182.1 - 0.095 12.7 9.1 0.12 12.4 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SPX PF03105.19 KFX93182.1 - 5 6.9 10.3 5.2 6.9 10.3 1.0 1 0 0 1 1 1 0 SPX domain Peroxin-3 PF04882.12 KFX93182.1 - 6.6 5.6 6.5 7.1 5.5 6.5 1.0 1 0 0 1 1 1 0 Peroxin-3 SOG2 PF10428.9 KFX93182.1 - 7.2 5.7 13.0 7.6 5.6 13.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pga1 PF10333.9 KFX93195.1 - 9e-06 25.7 0.4 3.7e-05 23.7 0.1 2.2 1 1 1 2 2 2 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 KFX93196.1 - 2.6e-67 226.8 0.0 3.7e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX93196.1 - 9.4e-50 168.0 0.1 1.8e-49 167.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFX93196.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.7 KFX93197.1 - 9e-34 115.6 0.0 2.8e-14 52.9 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KFX93197.1 - 9.6e-09 35.6 0.0 3.8e-05 24.1 0.0 4.0 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KFX93197.1 - 7.2e-07 28.3 0.0 0.12 12.0 0.0 5.0 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 KFX93197.1 - 0.00022 20.9 0.0 16 5.7 0.0 4.9 5 0 0 5 5 4 0 EF-hand domain UBA PF00627.31 KFX93197.1 - 0.00083 19.2 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Spc7 PF08317.11 KFX93197.1 - 0.0057 15.6 33.9 0.15 10.9 7.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein CCDC144C PF14915.6 KFX93197.1 - 0.036 13.2 29.3 0.0084 15.3 26.0 1.5 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region EF-hand_8 PF13833.6 KFX93197.1 - 0.062 13.2 0.0 29 4.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair MAD PF05557.13 KFX93197.1 - 0.1 11.0 24.6 0.14 10.5 24.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein MbeD_MobD PF04899.12 KFX93197.1 - 0.52 10.5 17.3 1.9 8.7 1.0 3.5 1 1 2 3 3 3 0 MbeD/MobD like HMMR_N PF15905.5 KFX93197.1 - 0.6 9.5 27.4 1.3 8.5 27.4 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 KFX93197.1 - 1.1 10.2 30.7 0.038 14.9 12.8 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 KFX93197.1 - 1.1 9.5 21.0 0.1 12.8 8.8 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KFX93197.1 - 1.1 6.7 32.5 1.6 6.2 32.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 KFX93197.1 - 1.3 9.2 39.3 0.79 9.9 20.4 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KFX93197.1 - 1.6 8.0 32.0 1.4 8.2 14.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 KFX93197.1 - 1.7 7.4 30.8 3.3 6.5 30.8 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 KFX93197.1 - 1.8 8.6 31.6 0.79 9.7 18.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 KFX93197.1 - 1.8 7.8 21.9 2.1 7.6 6.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF2968 PF11180.8 KFX93197.1 - 2.2 7.9 26.7 2.2 7.9 12.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Mto2_bdg PF12808.7 KFX93197.1 - 2.7 8.4 8.5 7.3 7.0 2.1 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TolA_bind_tri PF16331.5 KFX93197.1 - 2.8 8.1 33.6 0.045 13.8 6.5 3.8 2 1 2 4 4 3 0 TolA binding protein trimerisation Golgin_A5 PF09787.9 KFX93197.1 - 3 7.2 32.9 0.29 10.6 26.5 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4239 PF14023.6 KFX93197.1 - 3.2 7.4 4.5 5.7 6.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Tup_N PF08581.10 KFX93197.1 - 3.4 8.0 16.5 0.62 10.4 4.0 2.6 1 1 1 2 2 2 0 Tup N-terminal DUF724 PF05266.14 KFX93197.1 - 3.6 7.4 25.7 0.21 11.4 10.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KFX93197.1 - 3.9 7.5 15.3 1.2 9.2 7.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KFX93197.1 - 5 7.2 37.8 1.4 9.0 19.3 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 KFX93197.1 - 5 5.5 12.3 4.2 5.8 9.8 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family FAD-SLDH PF12318.8 KFX93197.1 - 7.7 6.6 14.2 2.1 8.4 3.6 2.8 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Macoilin PF09726.9 KFX93197.1 - 8.3 4.8 26.0 0.018 13.6 16.1 1.5 2 0 0 2 2 1 0 Macoilin family COG2 PF06148.11 KFX93197.1 - 9.5 6.3 15.9 0.56 10.3 4.7 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 eIF-3_zeta PF05091.12 KFX93212.1 - 1.4e-78 265.2 0.1 1.6e-78 265.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KFX93212.1 - 0.0076 15.9 0.0 0.034 13.8 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF569) HgmA PF04209.13 KFX93221.1 - 9.6e-137 456.1 0.1 1.1e-136 456.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.22 KFX93222.1 - 9.2e-66 222.5 0.0 1.1e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.21 KFX93223.1 - 1.2e-09 38.0 0.3 9.7e-09 35.0 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX93223.1 - 1.4e-08 34.8 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX93223.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KFX93223.1 - 3.2e-05 23.1 0.0 0.00041 19.5 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFX93223.1 - 0.004 17.4 0.1 0.0079 16.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 KFX93223.1 - 0.0045 16.2 0.5 0.01 15.0 0.2 1.7 1 1 1 2 2 2 1 Male sterility protein AlaDh_PNT_C PF01262.21 KFX93223.1 - 0.0095 15.2 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFX93223.1 - 0.01 16.4 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX93223.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KFX93223.1 - 0.033 14.3 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KFX93223.1 - 0.06 12.7 0.0 4.1 6.7 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KFX93223.1 - 0.064 13.8 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 KFX93223.1 - 0.084 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 KFX93223.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX93223.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PMT PF02366.18 KFX93235.1 - 2.1e-84 283.0 12.8 2.1e-84 283.0 12.8 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFX93235.1 - 1.6e-64 217.2 13.4 1.6e-64 217.2 13.4 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFX93235.1 - 1.5e-37 129.3 0.4 2.2e-37 128.7 0.4 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KFX93235.1 - 0.083 12.7 0.3 2.1 8.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Sugar_tr PF00083.24 KFX93236.1 - 2.1e-105 353.2 18.0 2.5e-105 352.9 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93236.1 - 2.5e-32 112.2 41.7 1.4e-29 103.1 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX93236.1 - 2.3e-06 26.5 23.2 5.5e-06 25.2 6.4 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KFX93236.1 - 0.0031 16.5 1.1 0.0053 15.7 1.1 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX93236.1 - 0.017 14.0 7.4 0.15 10.9 0.1 2.5 2 1 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 KFX93236.1 - 0.49 8.7 5.6 1 7.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Chs7 PF12271.8 KFX93237.1 - 2.4e-112 375.0 4.9 2.7e-112 374.8 4.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF998 PF06197.13 KFX93237.1 - 0.0064 16.1 11.3 0.011 15.4 0.6 2.5 2 2 0 2 2 2 2 Protein of unknown function (DUF998) TssN PF17555.2 KFX93237.1 - 0.013 14.9 4.7 0.013 14.9 4.7 2.1 2 1 0 2 2 2 0 Type VI secretion system, TssN YvrJ PF12841.7 KFX93237.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family FixQ PF05545.11 KFX93237.1 - 1.6 8.7 4.3 4.3 7.4 0.0 3.3 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF202 PF02656.15 KFX93237.1 - 2.1 8.8 0.0 2.1 8.8 0.0 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Ssl1 PF04056.14 KFX93238.1 - 5.9e-51 173.0 0.0 7.6e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFX93238.1 - 1.7e-14 54.4 0.0 2.7e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX93238.1 - 0.00095 19.5 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain MFS_1 PF07690.16 KFX93241.1 - 4.4e-33 114.7 59.2 3.5e-32 111.7 58.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX93241.1 - 4.1e-07 28.8 23.5 5.4e-07 28.4 23.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sterol-sensing PF12349.8 KFX93244.1 - 2.8e-42 144.1 7.0 6.8e-42 142.9 7.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFX93244.1 - 1.1e-11 43.6 6.3 1.6e-11 43.1 6.3 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KFX93244.1 - 0.085 13.8 3.1 0.28 12.1 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Flavoprotein PF02441.19 KFX93244.1 - 0.14 11.9 0.2 0.36 10.5 0.2 1.7 1 0 0 1 1 1 0 Flavoprotein Sugar_tr PF00083.24 KFX93245.1 - 1.9e-86 290.7 20.6 2.2e-86 290.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93245.1 - 4.5e-29 101.5 29.6 1.3e-18 67.1 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KFX93248.1 - 4.2e-06 26.8 8.8 4.2e-06 26.8 8.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYTT PF07078.11 KFX93248.1 - 0.013 14.8 0.6 0.02 14.2 0.6 1.2 1 0 0 1 1 1 0 Forty-two-three protein MFS_1 PF07690.16 KFX93250.1 - 4.4e-27 94.9 48.2 2e-25 89.5 43.8 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX93250.1 - 6.9e-20 71.0 14.6 2.7e-19 69.0 14.6 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4519 PF15012.6 KFX93250.1 - 2.3 8.4 5.5 1.5 9.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Abhydrolase_6 PF12697.7 KFX93253.1 - 8.4e-20 72.3 2.1 9.6e-20 72.1 2.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family LANC_like PF05147.13 KFX93254.1 - 1.2e-21 76.8 0.0 3.8e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_transf_54 PF04666.13 KFX93255.1 - 1.7e-10 40.2 0.2 2.5e-09 36.4 0.2 2.2 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region PNTB PF02233.16 KFX93255.1 - 0.29 10.0 0.1 0.44 9.4 0.1 1.2 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit DUF3292 PF11696.8 KFX93255.1 - 1.1 7.6 4.1 1.7 6.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Tho2 PF11262.8 KFX93255.1 - 2.2 7.4 8.6 3.5 6.8 8.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CDC45 PF02724.14 KFX93255.1 - 2.5 6.3 5.3 3.5 5.8 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4131 PF13567.6 KFX93255.1 - 7.7 6.1 9.1 3.9 7.1 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) End_beta_barrel PF12195.8 KFX93256.1 - 0.054 13.5 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase DNA_pol_phi PF04931.13 KFX93256.1 - 0.39 8.7 2.8 0.69 8.0 2.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KFX93256.1 - 0.85 8.9 11.3 0.18 11.1 4.5 2.3 2 0 0 2 2 2 0 NOA36 protein Acetyltransf_10 PF13673.7 KFX93257.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93257.1 - 1.9e-08 34.5 0.0 4.8e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX93257.1 - 3.3e-08 33.8 0.0 1.2e-07 32.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX93257.1 - 5.4e-05 23.1 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KFX93257.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFX93257.1 - 0.0021 18.1 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 KFX93258.1 - 2.5e-52 177.9 0.1 3.1e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX93258.1 - 8.5e-13 48.7 0.0 1.1e-10 41.9 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX93258.1 - 0.00044 19.6 0.2 0.69 9.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX93258.1 - 1.8 7.2 4.6 0.94 8.1 0.1 2.4 2 1 1 3 3 3 0 HI0933-like protein ABC_tran PF00005.27 KFX93259.1 - 5.8e-34 117.6 0.0 1.5e-33 116.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFX93259.1 - 1.1e-33 117.1 7.3 1.7e-33 116.5 7.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFX93259.1 - 8.3e-08 31.9 3.1 1.2e-06 28.2 3.1 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX93259.1 - 0.002 18.5 0.1 0.0078 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX93259.1 - 0.0061 16.8 0.3 0.048 13.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KFX93259.1 - 0.0064 16.7 0.3 0.12 12.6 0.3 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KFX93259.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFX93259.1 - 0.028 14.2 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX93259.1 - 0.19 12.2 0.4 0.44 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pro_isomerase PF00160.21 KFX93265.1 - 1.4e-49 168.4 0.0 1.8e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 KFX93265.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain RRM_1 PF00076.22 KFX93276.1 - 3e-13 49.4 0.4 6.2e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt5_N PF11942.8 KFX93276.1 - 0.00013 22.9 4.1 0.00021 22.2 4.1 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal RRM_7 PF16367.5 KFX93276.1 - 0.0054 16.8 0.0 0.027 14.6 0.0 2.2 1 1 0 2 2 2 1 RNA recognition motif YL1 PF05764.13 KFX93276.1 - 0.008 16.3 2.5 0.0092 16.1 2.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein TIMELESS_C PF05029.13 KFX93276.1 - 0.012 14.8 2.0 0.013 14.7 2.0 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region CENP-B_dimeris PF09026.10 KFX93276.1 - 0.026 14.9 2.5 0.041 14.3 2.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PAN_3 PF08277.12 KFX93276.1 - 0.047 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain CDC45 PF02724.14 KFX93276.1 - 0.065 11.5 1.1 0.065 11.5 1.1 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KFX93276.1 - 0.087 12.8 1.5 0.14 12.2 1.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CCDC84 PF14968.6 KFX93276.1 - 0.19 11.3 1.9 0.27 10.8 1.9 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 PBP1_TM PF14812.6 KFX93276.1 - 0.21 12.0 3.8 0.39 11.1 3.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COQ7 PF03232.13 KFX93283.1 - 1.2e-51 174.9 0.7 1.3e-51 174.8 0.7 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PLDc PF00614.22 KFX93284.1 - 2.1e-17 62.5 0.4 7.6e-08 32.2 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFX93284.1 - 1.7e-12 47.4 0.0 9.1e-07 28.8 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KFX93284.1 - 8.6e-07 28.9 0.1 2.7e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 PX domain DASH_Spc34 PF08657.10 KFX93291.1 - 2e-49 168.7 8.6 6.8e-25 88.3 3.8 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 MAP65_ASE1 PF03999.12 KFX93291.1 - 0.031 13.0 2.3 0.039 12.7 2.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DASH_Spc19 PF08287.11 KFX93291.1 - 0.09 12.7 7.2 0.12 12.2 6.9 1.4 1 1 0 1 1 1 0 Spc19 DUF724 PF05266.14 KFX93291.1 - 0.11 12.3 3.2 0.16 11.8 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 KFX93291.1 - 0.33 11.6 8.9 0.91 10.2 1.9 2.6 1 1 1 2 2 2 0 SlyX CRA PF06589.11 KFX93291.1 - 0.4 10.8 1.2 0.67 10.1 1.2 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DHR10 PF18595.1 KFX93291.1 - 0.55 10.3 10.2 2.6 8.1 2.6 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CAF1A PF12253.8 KFX93291.1 - 4 7.7 7.8 7.8 6.8 7.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A TFIID_20kDa PF03847.13 KFX93292.1 - 4.2e-22 78.4 0.0 6.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFX93292.1 - 0.0015 18.7 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX93292.1 - 0.41 11.0 0.0 0.41 11.0 0.0 3.9 5 0 0 5 5 5 0 Core histone H2A/H2B/H3/H4 ORC5_C PF14630.6 KFX93293.1 - 9.5e-45 153.3 0.3 9.5e-45 153.3 0.3 2.5 3 0 0 3 3 3 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KFX93293.1 - 4e-08 33.8 0.0 1.2e-07 32.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFX93293.1 - 0.024 14.5 0.0 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 NACHT domain TPT PF03151.16 KFX93294.1 - 2.3e-55 188.0 7.8 2.8e-55 187.7 7.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFX93294.1 - 4.1e-09 36.7 28.8 3.1e-05 24.2 8.8 3.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFX93294.1 - 4e-05 23.0 14.9 0.00061 19.1 14.9 2.2 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.19 KFX93294.1 - 0.002 16.9 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Photosystem II protein DUF382 PF04037.13 KFX93295.1 - 7.6e-59 197.4 0.5 7.6e-59 197.4 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 KFX93295.1 - 1.8e-20 72.5 4.3 5e-20 71.1 4.3 1.8 1 0 0 1 1 1 1 PSP 40S_SA_C PF16122.5 KFX93295.1 - 0.09 14.1 0.2 0.09 14.1 0.2 3.6 3 0 0 3 3 3 0 40S ribosomal protein SA C-terminus CN_hydrolase PF00795.22 KFX93296.1 - 7.6e-42 143.4 0.0 1.1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFX93296.1 - 3.9e-22 78.5 0.0 1.4e-21 76.7 0.0 1.9 1 1 0 1 1 1 1 NAD synthase MINDY_DUB PF04424.13 KFX93297.1 - 2.7e-21 75.7 0.0 4.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase DUF1388 PF07142.12 KFX93298.1 - 0.0027 17.6 5.1 0.0027 17.6 5.1 6.7 5 2 2 7 7 7 4 Repeat of unknown function (DUF1388) F-box-like PF12937.7 KFX93299.1 - 0.0065 16.3 1.2 0.013 15.3 1.2 1.6 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 KFX93300.1 - 2.5e-73 242.7 38.3 6.9e-14 52.2 1.8 6.9 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93300.1 - 2.5e-47 158.7 16.5 3.2e-10 40.3 0.4 8.6 6 1 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX93300.1 - 1.1e-44 145.3 15.8 0.00077 19.7 0.2 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 KFX93300.1 - 6.4e-39 130.7 39.8 3.8e-05 23.9 0.2 11.5 12 1 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KFX93300.1 - 4.7e-33 112.8 18.3 3.2e-08 33.7 1.3 9.6 4 1 5 10 10 10 7 Ankyrin repeats (many copies) EccE PF11203.8 KFX93300.1 - 0.022 15.0 0.6 1.9 8.8 0.0 3.1 1 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE VWA_3_C PF18571.1 KFX93300.1 - 0.22 11.4 2.1 56 3.7 0.1 4.5 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain DUF1843 PF08898.10 KFX93300.1 - 0.3 11.6 3.0 10 6.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Cast PF10174.9 KFX93302.1 - 4.4e-05 21.9 29.9 7.4e-05 21.2 29.9 1.4 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone FAM76 PF16046.5 KFX93302.1 - 2.1 7.7 41.2 0.28 10.5 18.8 2.4 1 1 1 2 2 2 0 FAM76 protein HOOK PF05622.12 KFX93302.1 - 4.9 5.2 39.8 0.037 12.2 20.1 2.1 1 1 1 2 2 2 0 HOOK protein Na_H_Exchanger PF00999.21 KFX93303.1 - 1.1e-37 129.8 9.2 1.1e-37 129.8 9.2 4.0 3 2 1 4 4 4 2 Sodium/hydrogen exchanger family MFS_1 PF07690.16 KFX93303.1 - 1.8e-22 79.8 38.6 1.8e-22 79.8 38.6 3.9 3 1 0 3 3 3 1 Major Facilitator Superfamily Peptidase_M20 PF01546.28 KFX93304.1 - 5e-08 32.9 0.1 7.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX93304.1 - 2.6e-05 24.1 0.2 0.00019 21.3 0.1 2.2 2 1 0 2 2 2 1 Peptidase dimerisation domain Sugar_tr PF00083.24 KFX93305.1 - 1.4e-83 281.3 23.4 1.6e-83 281.1 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93305.1 - 6.3e-26 91.1 45.9 1e-22 80.6 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFX93306.1 - 8.3e-36 123.6 46.8 8.6e-36 123.6 44.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX93306.1 - 6.8e-10 38.0 23.5 6.8e-10 38.0 23.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GPR15L PF15854.5 KFX93306.1 - 0.053 13.8 1.6 0.13 12.5 0.2 2.2 1 1 1 2 2 2 0 G-protein coupled receptor ligand 15 GYF PF02213.16 KFX93307.1 - 6.7e-10 38.5 0.9 1.5e-09 37.3 0.9 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 KFX93308.1 - 1.7e-73 245.8 0.0 2.1e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 BolA PF01722.18 KFX93311.1 - 2.5e-11 43.7 0.0 4.8e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein tRNA-synt_1d PF00750.19 KFX93312.1 - 5.7e-102 341.2 5.9 7.8e-102 340.8 5.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFX93312.1 - 1.6e-30 105.7 0.1 4.7e-30 104.2 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KFX93312.1 - 1.8e-07 31.6 0.0 5.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 KFX93312.1 - 0.11 12.3 0.0 0.4 10.5 0.0 1.9 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 Hemerythrin PF01814.23 KFX93313.1 - 1.2e-06 29.1 0.0 2.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_61 PF03443.14 KFX93314.1 - 3.7e-48 164.2 0.0 4.3e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F5_F8_type_C PF00754.25 KFX93315.1 - 1.6e-10 41.2 0.0 4e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_42 PF02449.15 KFX93315.1 - 0.015 14.7 0.0 0.56 9.5 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase Sugar_tr PF00083.24 KFX93316.1 - 3.4e-81 273.4 24.0 3.9e-81 273.2 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93316.1 - 5.9e-40 137.3 49.6 2.6e-34 118.7 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX93316.1 - 0.0096 14.8 12.5 0.014 14.3 3.1 2.3 1 1 1 2 2 2 2 MFS_1 like family TRI12 PF06609.13 KFX93316.1 - 0.045 12.2 10.7 0.0065 14.9 3.4 2.5 2 1 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Alpha-amylase PF00128.24 KFX93317.1 - 2.4e-112 375.8 0.1 2.4e-112 375.8 0.1 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX93317.1 - 6.2e-09 35.9 0.0 1.7e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX93317.1 - 0.0022 17.2 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KFX93317.1 - 0.035 14.6 0.4 0.35 11.4 0.2 2.6 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain DUF4202 PF13875.6 KFX93318.1 - 4.6e-77 258.2 1.5 5.1e-77 258.0 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF5584 PF17822.1 KFX93318.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5584) Kinesin_assoc PF16183.5 KFX93318.1 - 0.064 13.4 0.3 0.08 13.1 0.3 1.2 1 0 0 1 1 1 0 Kinesin-associated Glyco_hydro_31 PF01055.26 KFX93319.1 - 3.3e-113 379.2 1.2 4.7e-113 378.7 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFX93319.1 - 4.7e-07 30.0 0.0 7.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KFX93319.1 - 0.00018 21.7 1.0 0.0013 19.0 0.2 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like Peptidase_M20 PF01546.28 KFX93320.1 - 1.2e-23 84.0 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX93320.1 - 9.7e-15 54.4 0.0 2.8e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain SIMPL PF04402.14 KFX93320.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) APH PF01636.23 KFX93321.1 - 7.1e-17 62.1 0.1 1.1e-16 61.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX93321.1 - 0.0002 21.0 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KFX93321.1 - 0.018 14.4 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFX93321.1 - 0.033 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93321.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Mito_carr PF00153.27 KFX93328.1 - 1.3e-55 185.2 0.9 2e-19 69.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX93328.1 - 0.008 15.4 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Gammaproteobacterial serine protease UcrQ PF02939.16 KFX93328.1 - 0.034 14.1 0.3 0.78 9.7 0.0 2.5 2 0 0 2 2 2 0 UcrQ family BTB PF00651.31 KFX93329.1 - 6.9e-06 26.3 0.0 0.00035 20.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain PAF-AH_p_II PF03403.13 KFX93348.1 - 4.9e-09 35.2 0.1 4.2e-08 32.1 0.0 2.0 1 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFX93348.1 - 5.3e-05 22.3 0.0 7.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KFX93348.1 - 0.013 15.3 0.1 0.099 12.4 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ank_2 PF12796.7 KFX93349.1 - 6.9e-82 270.1 11.5 2e-13 50.7 0.0 6.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93349.1 - 3e-56 187.1 1.2 8.5e-09 35.8 0.0 10.5 3 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX93349.1 - 1.9e-46 150.7 1.2 0.0045 17.4 0.0 13.2 12 1 1 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KFX93349.1 - 2.4e-34 116.9 8.7 3.2e-05 24.1 0.0 11.0 1 1 12 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX93349.1 - 5.9e-33 111.9 15.9 0.028 14.9 0.0 12.8 10 2 2 12 12 12 8 Ankyrin repeat DUF4646 PF15496.6 KFX93349.1 - 0.00077 20.1 0.3 0.0078 16.8 0.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF249 PF03158.13 KFX93349.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Multigene family 530 protein DUF2236 PF09995.9 KFX93351.1 - 9.8e-28 97.9 0.0 1.6e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2520 PF10728.9 KFX93351.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Glyco_hydro_30 PF02055.16 KFX93352.1 - 5.5e-26 91.4 1.4 9.3e-17 61.0 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain DUF3425 PF11905.8 KFX93352.1 - 1.1e-14 54.4 0.5 1.1e-14 54.4 0.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3425) Glyco_hydro_30C PF17189.4 KFX93352.1 - 7.6e-05 22.9 0.6 0.00019 21.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain bZIP_1 PF00170.21 KFX93352.1 - 0.00012 22.1 7.8 0.0018 18.3 7.8 2.5 1 1 1 2 2 2 2 bZIP transcription factor Sugar_tr PF00083.24 KFX93353.1 - 3.9e-46 157.8 1.2 5.5e-46 157.4 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93353.1 - 2.7e-33 115.4 50.8 3.8e-29 101.7 32.9 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX93353.1 - 0.00069 18.6 2.3 0.095 11.5 0.2 2.9 2 2 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KFX93353.1 - 0.0024 16.6 7.7 0.014 14.1 3.3 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like LacY_symp PF01306.19 KFX93353.1 - 0.71 8.6 8.1 2 7.1 5.8 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter Phosphoesterase PF04185.14 KFX93354.1 - 8.7e-66 222.5 2.1 1.1e-65 222.2 2.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 KFX93355.1 - 1.1e-61 208.5 3.8 1.3e-61 208.2 3.8 1.1 1 0 0 1 1 1 1 VIT family K_oxygenase PF13434.6 KFX93356.1 - 1.3e-13 50.9 0.0 7.3e-10 38.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX93356.1 - 1.4e-13 50.8 0.0 1.2e-12 47.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX93356.1 - 1.7e-12 46.6 0.0 5.2e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX93356.1 - 1.2e-08 34.5 0.0 3.1e-06 26.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX93356.1 - 0.00088 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX93356.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KFX93356.1 - 0.004 17.2 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFX93356.1 - 0.022 13.8 0.0 0.071 12.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KFX93356.1 - 0.11 11.1 0.1 9.9 4.7 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 KFX93356.1 - 0.16 11.5 0.4 3.1 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KFX93357.1 - 2.4e-22 79.3 30.9 2.4e-22 79.3 30.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX93357.1 - 5.8e-11 41.9 6.6 5.8e-11 41.9 6.6 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter LapA_dom PF06305.11 KFX93357.1 - 0.019 14.8 2.2 1.3 8.9 0.3 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1449 PF07290.11 KFX93357.1 - 0.14 11.8 1.5 0.32 10.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Beta_elim_lyase PF01212.21 KFX93358.1 - 1.1e-62 212.0 0.0 1.4e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFX93358.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 KFX93359.1 - 1.8e-07 30.8 0.0 3e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFX93359.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX93359.1 - 0.0087 16.0 0.2 13 5.6 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family MNHE PF01899.16 KFX93360.1 - 0.00029 20.6 0.3 0.00031 20.5 0.3 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit Peptidase_M20 PF01546.28 KFX93361.1 - 2.2e-28 99.4 0.0 4.5e-28 98.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX93361.1 - 2.4e-11 43.5 0.0 5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFX93361.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 PurS PF02700.14 KFX93362.1 - 0.14 12.4 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Abhydrolase_1 PF00561.20 KFX93363.1 - 2e-20 73.5 0.0 7.4e-19 68.4 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX93363.1 - 3.5e-17 62.5 0.0 1.3e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX93363.1 - 1.5e-15 58.5 0.0 1.8e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFX93363.1 - 1.7e-06 27.0 0.0 3.8e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family DUF1749 PF08538.10 KFX93363.1 - 3e-06 26.5 0.0 0.00015 20.9 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 KFX93363.1 - 0.00016 21.5 0.0 0.00063 19.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 KFX93363.1 - 0.00084 19.3 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 KFX93363.1 - 0.0037 16.9 0.0 0.0079 15.8 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF1057 PF06342.12 KFX93363.1 - 0.0048 16.0 0.0 0.0061 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 KFX93363.1 - 0.0085 15.9 0.0 16 5.2 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 KFX93363.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase_phd PF10503.9 KFX93363.1 - 0.025 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX93363.1 - 0.037 13.5 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KFX93363.1 - 0.044 13.4 0.0 0.056 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DLH PF01738.18 KFX93363.1 - 0.072 12.6 0.0 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 KFX93363.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KFX93363.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFX93363.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase PAF-AH_p_II PF03403.13 KFX93363.1 - 0.18 10.3 0.1 2.8 6.4 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Alkyl_sulf_dimr PF14863.6 KFX93364.1 - 2.5e-58 196.5 0.0 4.2e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KFX93364.1 - 5.5e-31 108.1 0.0 9.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 KFX93364.1 - 5.5e-28 97.8 0.0 9.4e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 KFX93364.1 - 9.1e-06 25.3 0.0 2.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF1583 PF07622.11 KFX93364.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) p450 PF00067.22 KFX93365.1 - 1.9e-20 73.0 0.0 4.9e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KFX93365.1 - 1.9e-11 43.8 0.1 4.7e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase FAD_binding_3 PF01494.19 KFX93365.1 - 3.7e-07 29.7 0.0 0.12 11.6 0.0 3.3 3 0 0 3 3 3 2 FAD binding domain KR PF08659.10 KFX93365.1 - 4.2e-07 30.0 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX93365.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_8 PF13450.6 KFX93365.1 - 0.00025 21.2 0.1 0.00068 19.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX93365.1 - 0.034 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX93365.1 - 0.037 13.3 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Semialdhyde_dh PF01118.24 KFX93365.1 - 0.039 14.4 0.3 9 6.8 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KFX93365.1 - 0.071 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Aminotran_1_2 PF00155.21 KFX93366.1 - 3.2e-46 158.2 0.0 3.8e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KFX93366.1 - 0.14 10.8 0.0 0.59 8.7 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-III ABM PF03992.16 KFX93367.1 - 0.15 12.2 0.2 19 5.5 0.1 2.9 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase BNR_2 PF13088.6 KFX93368.1 - 0.0008 18.8 0.1 0.0024 17.3 0.0 1.7 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFX93368.1 - 0.0012 18.6 5.8 1.3 9.3 0.0 4.1 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KFX93368.1 - 0.22 10.3 0.7 15 4.3 0.1 2.3 1 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, Sua5_yciO_yrdC PF01300.18 KFX93369.1 - 5.8e-54 182.3 0.0 7.8e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KFX93369.1 - 2.7e-28 99.2 0.0 5.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.20 KFX93370.1 - 1.5e-14 54.2 0.2 1.5e-13 50.9 0.4 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain MCM PF00493.23 KFX93371.1 - 2.4e-101 337.5 0.0 3.5e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFX93371.1 - 1.7e-39 134.5 1.0 3.3e-39 133.6 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFX93371.1 - 1.1e-29 102.6 3.7 2.9e-29 101.3 3.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFX93371.1 - 9.6e-20 71.1 0.0 3.2e-19 69.4 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFX93371.1 - 3e-06 26.8 0.0 0.00016 21.1 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFX93371.1 - 2.7e-05 24.2 0.1 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFX93371.1 - 0.00029 20.7 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KFX93371.1 - 0.1 12.4 0.3 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA lid domain Sigma54_activat PF00158.26 KFX93371.1 - 0.11 12.1 0.2 2.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.10 KFX93371.1 - 0.13 12.4 1.5 0.31 11.2 1.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AAA_16 PF13191.6 KFX93371.1 - 0.57 10.6 2.5 8.6 6.7 2.5 3.0 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase_C PF13335.6 KFX93371.1 - 1.7 9.4 6.5 0.66 10.7 1.8 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Abhydrolase_6 PF12697.7 KFX93376.1 - 2.1e-14 54.7 0.6 2.5e-14 54.4 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3425 PF11905.8 KFX93377.1 - 4.7e-10 39.5 2.4 6e-09 35.9 2.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Ank_4 PF13637.6 KFX93378.1 - 1.6e-09 38.1 0.0 8.1e-08 32.7 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX93378.1 - 1.8e-09 38.1 0.0 5.4e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX93378.1 - 0.00039 20.7 0.0 0.041 14.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX93378.1 - 0.0005 20.4 0.3 1.2 9.7 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFX93378.1 - 0.019 15.4 0.0 57 4.8 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat WSC PF01822.19 KFX93379.1 - 1.6e-30 105.1 18.5 1.3e-17 63.7 7.0 3.4 3 0 0 3 3 3 2 WSC domain CENP-B_N PF04218.13 KFX93385.1 - 1.7e-08 33.9 0.5 3.7e-08 32.9 0.5 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain zf-H2C2_5 PF13909.6 KFX93385.1 - 0.057 13.2 0.4 0.13 12.0 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Exo_endo_phos PF03372.23 KFX93389.1 - 4.9e-09 36.0 0.0 9.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family fn3_5 PF06280.12 KFX93389.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Fn3-like domain Lantibiotic_a PF14867.6 KFX93389.1 - 0.32 10.8 1.2 0.81 9.5 0.6 1.9 2 0 0 2 2 2 0 Lantibiotic alpha DCP1 PF06058.13 KFX93390.1 - 2.2e-30 105.0 0.0 2.9e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Glyco_hydro_1 PF00232.18 KFX93391.1 - 1.1e-151 505.3 0.0 1.3e-151 505.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Histidinol_dh PF00815.20 KFX93398.1 - 5.1e-144 480.3 4.1 9.2e-144 479.4 4.1 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KFX93398.1 - 1.4e-23 82.5 0.1 2.8e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase SGTA_dimer PF16546.5 KFX93398.1 - 5.6e-22 77.3 0.3 5.6e-22 77.3 0.3 2.2 3 0 0 3 3 3 1 Homodimerisation domain of SGTA PRA-PH PF01503.17 KFX93398.1 - 6.8e-14 52.1 0.5 2.4e-13 50.3 0.5 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_2 PF07719.17 KFX93398.1 - 5.5e-05 23.0 0.0 0.0002 21.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93398.1 - 0.00024 20.8 0.0 0.00092 18.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX93398.1 - 0.02 14.5 0.2 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 KFX93398.1 - 0.04 14.6 0.0 0.2 12.3 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat MazG PF03819.17 KFX93398.1 - 0.16 12.1 2.5 0.24 11.6 0.9 2.1 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain TFIID-31kDa PF02291.15 KFX93399.1 - 5.3e-44 149.2 0.0 7.1e-44 148.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Pre-PUA PF17832.1 KFX93400.1 - 9.6e-25 87.1 0.4 1.3e-24 86.7 0.4 1.1 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFX93400.1 - 1.7e-13 50.3 0.3 6e-13 48.6 0.3 1.8 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KFX93400.1 - 0.0075 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) Inhibitor_I78 PF11720.8 KFX93401.1 - 0.00013 22.0 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KFX93401.1 - 0.002 18.7 0.0 0.0028 18.3 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family FTP PF07504.13 KFX93401.1 - 0.053 13.4 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Pet191_N PF10203.9 KFX93402.1 - 3.7 7.9 6.6 16 5.9 0.1 3.4 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF1992 PF09350.10 KFX93403.1 - 8.8e-18 64.2 0.0 3e-17 62.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 KFX93403.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Pyocin_S PF06958.12 KFX93403.1 - 0.12 12.9 4.3 0.059 13.9 1.8 1.7 2 0 0 2 2 2 0 S-type Pyocin ENTH PF01417.20 KFX93409.1 - 2.2e-46 157.0 0.3 2.9e-46 156.6 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFX93409.1 - 0.0016 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 KFX93409.1 - 0.088 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.21 KFX93410.1 - 1.6e-41 142.2 0.4 2.1e-41 141.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KFX93414.1 - 1.1e-18 67.8 0.1 7.1e-17 62.0 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 KFX93415.1 - 2.3e-45 154.7 0.2 4.4e-45 153.8 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Frag1 PF10277.9 KFX93416.1 - 4.5e-40 137.5 6.5 5.2e-40 137.3 6.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KFX93416.1 - 0.0085 15.7 6.5 0.015 14.9 6.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Cation_ATPase_C PF00689.21 KFX93416.1 - 0.7 9.6 6.9 1.1 9.0 6.9 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus TPR_2 PF07719.17 KFX93417.1 - 1e-38 128.3 20.5 1.5e-07 31.0 0.2 8.8 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93417.1 - 1.3e-34 116.6 20.2 2.6e-06 27.0 0.2 9.2 9 1 1 10 10 9 6 Tetratricopeptide repeat DnaJ PF00226.31 KFX93417.1 - 4.7e-27 93.9 5.6 1.8e-26 92.0 5.6 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KFX93417.1 - 3.4e-26 90.6 20.9 9e-07 28.5 0.2 7.6 6 1 2 8 8 8 6 TPR repeat TPR_16 PF13432.6 KFX93417.1 - 1.1e-23 83.6 13.2 3.1e-07 30.9 0.3 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX93417.1 - 1.5e-21 76.7 17.7 4.7e-06 27.0 0.8 6.3 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFX93417.1 - 2.4e-17 61.6 19.6 0.0017 18.4 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFX93417.1 - 3e-17 62.5 7.1 5e-05 23.4 0.1 5.3 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX93417.1 - 1.8e-16 60.2 19.2 0.0025 18.0 1.3 7.4 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFX93417.1 - 5.8e-16 57.3 15.6 0.0063 16.5 0.0 8.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX93417.1 - 6.3e-16 57.7 16.5 0.0001 22.8 0.2 8.1 5 2 4 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFX93417.1 - 5.1e-15 54.7 20.3 0.0049 17.2 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX93417.1 - 5.4e-15 55.4 9.9 5e-06 26.6 0.9 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFX93417.1 - 7e-10 38.9 18.8 0.018 15.7 0.2 9.0 8 1 1 9 9 9 2 Tetratricopeptide repeat BTAD PF03704.17 KFX93417.1 - 1e-08 35.7 7.7 0.12 12.8 0.1 4.8 3 2 0 3 3 3 3 Bacterial transcriptional activator domain TPR_4 PF07721.14 KFX93417.1 - 2.7e-08 33.7 0.3 0.073 13.7 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX93417.1 - 8.5e-06 25.2 13.4 0.066 12.4 1.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX93417.1 - 2.6e-05 23.9 22.6 0.26 11.2 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KFX93417.1 - 0.00021 20.8 4.0 0.14 11.5 0.3 3.2 2 1 0 3 3 3 2 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 KFX93417.1 - 0.0015 18.5 11.9 3.8 7.7 0.0 6.1 4 1 2 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KFX93417.1 - 0.006 16.9 14.9 0.051 13.9 0.1 5.3 2 2 3 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 KFX93417.1 - 0.0065 15.5 0.5 0.018 14.1 0.2 1.8 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 KFX93417.1 - 0.018 14.4 5.8 0.031 13.7 1.1 3.2 2 2 0 2 2 2 0 MalT-like TPR region MIT PF04212.18 KFX93417.1 - 0.027 14.5 10.7 13 6.0 3.4 5.2 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KFX93417.1 - 0.031 14.7 2.9 14 6.1 0.1 3.8 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation DUF4919 PF16266.5 KFX93417.1 - 0.037 14.0 1.7 1.1 9.1 0.6 3.1 2 1 1 3 3 2 0 Domain of unknown function (DUF4919) DUF4192 PF13830.6 KFX93417.1 - 0.041 14.0 5.4 0.025 14.6 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) PPR PF01535.20 KFX93417.1 - 0.051 13.8 0.1 17 5.9 0.0 3.9 5 0 0 5 5 2 0 PPR repeat DUF928 PF06051.12 KFX93417.1 - 0.066 13.1 0.2 0.066 13.1 0.2 1.8 2 0 0 2 2 1 0 Domain of Unknown Function (DUF928) TPR_21 PF09976.9 KFX93417.1 - 0.12 12.1 17.4 0.4 10.3 0.4 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 KFX93417.1 - 0.13 12.3 7.8 0.2 11.7 0.1 4.0 2 2 1 4 4 4 0 Putative TPR-like repeat Wzy_C_2 PF11846.8 KFX93417.1 - 0.39 10.6 2.8 1.9 8.3 0.2 2.8 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TOM20_plant PF06552.12 KFX93417.1 - 2.6 7.8 6.8 8.5 6.1 0.1 3.6 3 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_5 PF12688.7 KFX93417.1 - 3.4 7.9 5.8 52 4.1 0.1 3.8 5 0 0 5 5 4 0 Tetratrico peptide repeat Apt1 PF10351.9 KFX93417.1 - 8.8 5.1 9.9 19 4.0 9.9 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_C50 PF03568.17 KFX93418.1 - 4.5e-159 529.8 0.0 8.5e-159 528.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 KFX93418.1 - 1e-07 32.1 16.6 0.038 14.3 0.2 7.0 6 2 2 8 8 8 4 Tetratricopeptide repeat CHAT PF12770.7 KFX93418.1 - 0.00047 19.7 1.1 0.083 12.3 0.0 3.5 3 1 0 4 4 4 2 CHAT domain TPR_2 PF07719.17 KFX93418.1 - 0.014 15.5 11.0 8.4 6.8 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX93418.1 - 0.92 8.8 13.5 0.17 11.2 1.2 4.3 5 1 0 5 5 5 0 MalT-like TPR region DUF5321 PF17254.2 KFX93419.1 - 4.3e-63 211.5 1.1 5.4e-63 211.2 1.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) IES5 PF17335.2 KFX93419.1 - 0.039 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Ino80 complex subunit 5 LcrG PF07216.12 KFX93419.1 - 0.21 11.5 2.1 0.44 10.5 2.1 1.5 1 1 0 1 1 1 0 LcrG protein DUF1654 PF07867.11 KFX93419.1 - 0.6 9.9 3.3 0.32 10.7 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) SIR2 PF02146.17 KFX93420.1 - 5.7e-31 107.8 0.0 8.2e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 KFX93421.1 - 1.8e-47 161.7 8.2 2.2e-47 161.4 8.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFX93421.1 - 4.7e-05 23.4 0.0 8.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter LIM PF00412.22 KFX93422.1 - 0.00011 22.4 3.1 0.00011 22.4 3.1 2.3 2 0 0 2 2 2 1 LIM domain Iso_dh PF00180.20 KFX93423.1 - 4.4e-121 404.3 0.0 5.1e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 KFX93425.1 - 2.8e-07 30.3 12.6 4.5e-07 29.7 12.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFX93425.1 - 7.5 7.0 7.8 0.74 10.2 2.3 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx EGF_2 PF07974.13 KFX93426.1 - 2.3e-05 24.6 5.0 0.0001 22.6 5.0 2.0 1 1 0 1 1 1 1 EGF-like domain EB PF01683.18 KFX93426.1 - 0.14 12.4 0.8 0.27 11.5 0.8 1.4 1 0 0 1 1 1 0 EB module I-EGF_1 PF18372.1 KFX93426.1 - 0.33 11.1 1.7 0.87 9.7 1.7 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 KFX93426.1 - 0.58 10.3 3.9 1.1 9.4 3.9 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF PF00008.27 KFX93426.1 - 0.65 10.4 3.3 2.9 8.3 3.3 2.0 1 1 0 1 1 1 0 EGF-like domain DUF4451 PF14616.6 KFX93429.1 - 2.5e-24 85.8 0.1 5.7e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Med10 PF09748.9 KFX93430.1 - 2.2e-46 156.8 0.0 2.5e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4972 PF16342.5 KFX93430.1 - 0.0039 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) DUF3877 PF12993.7 KFX93430.1 - 0.13 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Xpo1 PF08389.12 KFX93431.1 - 5.7e-38 130.3 0.0 2.6e-37 128.1 0.0 2.3 1 0 0 1 1 1 1 Exportin 1-like protein HEAT PF02985.22 KFX93431.1 - 0.025 14.8 0.2 19 5.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DUF3486 PF11985.8 KFX93431.1 - 0.076 13.4 0.0 0.31 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) TetR_C_33 PF13305.6 KFX93431.1 - 0.13 13.1 1.0 1.2 9.9 0.2 2.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EF-hand_6 PF13405.6 KFX93433.1 - 6.6e-11 41.2 0.8 5.9e-05 22.7 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFX93433.1 - 6.6e-10 37.8 1.4 0.00057 19.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFX93433.1 - 8.2e-07 29.4 3.6 9.5e-06 26.0 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFX93433.1 - 2.8e-06 27.1 0.1 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFX93433.1 - 2.3e-05 23.7 4.6 0.0085 15.6 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KFX93433.1 - 4.1e-05 23.8 0.0 0.085 13.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain MoeA_C PF03454.15 KFX93433.1 - 0.14 12.3 0.2 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) ORC6 PF05460.13 KFX93433.1 - 0.43 9.8 11.2 0.59 9.3 11.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 KFX93433.1 - 2.2 6.9 8.9 2.3 6.8 8.9 1.1 1 0 0 1 1 1 0 Hamartin protein Afi1 PF07792.12 KFX93434.1 - 4.4e-48 163.1 0.7 1.2e-47 161.8 0.7 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KFX93434.1 - 1.1e-38 131.7 0.0 2.1e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFX93434.1 - 8.9e-09 34.5 0.0 0.0072 15.1 0.0 4.0 3 1 1 4 4 4 2 Transport protein Avl9 Cwf_Cwc_15 PF04889.12 KFX93434.1 - 0.0011 18.8 6.4 0.0021 17.8 6.4 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2347 PF09804.9 KFX93434.1 - 0.012 15.2 0.0 0.1 12.2 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) TFIIA PF03153.13 KFX93434.1 - 0.31 11.0 8.6 0.71 9.8 8.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 KFX93434.1 - 1.8 8.4 10.5 0.25 11.2 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Esterase PF00756.20 KFX93435.1 - 1.1e-51 175.9 0.0 1.3e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KFX93435.1 - 1.3e-05 24.8 0.0 0.00089 18.8 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KFX93435.1 - 1.5e-05 24.4 0.0 0.0029 16.9 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX93435.1 - 6.9e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KFX93435.1 - 0.00065 18.7 0.0 0.0013 17.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFX93435.1 - 0.0066 15.5 0.0 0.14 11.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 KFX93435.1 - 0.015 14.8 0.2 0.099 12.2 0.1 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 KFX93435.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 KFX93435.1 - 0.024 14.3 0.1 0.047 13.4 0.0 1.4 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KFX93435.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 KFX93435.1 - 0.16 10.4 0.0 0.28 9.6 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RNA_pol_Rpb6 PF01192.22 KFX93436.1 - 5e-17 61.6 0.2 7.6e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 KFX93437.1 - 3.4e-08 33.5 5.3 0.00072 19.9 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX93437.1 - 5.4e-05 23.4 0.1 5.4e-05 23.4 0.1 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX93437.1 - 0.00085 20.0 12.7 0.018 15.8 0.3 3.4 2 1 1 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KFX93437.1 - 0.0015 18.9 0.4 0.42 11.1 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX93437.1 - 0.0026 18.0 2.1 0.11 12.9 1.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KFX93437.1 - 0.02 15.6 1.3 0.042 14.5 1.3 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf_Hakai PF18408.1 KFX93437.1 - 0.037 13.7 0.5 0.037 13.7 0.5 2.2 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 KFX93437.1 - 0.038 14.6 1.7 3.4 8.4 0.5 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain MMR_HSR1 PF01926.23 KFX93454.1 - 1.8e-13 50.5 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX93454.1 - 9.5e-06 25.2 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KFX93454.1 - 0.0084 15.1 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KFX93454.1 - 0.01 15.9 0.3 0.2 11.7 0.1 2.2 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KFX93454.1 - 0.015 15.2 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KFX93454.1 - 0.052 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.25 KFX93455.1 - 1.1e-68 231.4 0.0 2.7e-68 230.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX93455.1 - 3.8e-43 146.6 0.1 6e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFX93455.1 - 4.7e-05 23.7 0.1 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFX93455.1 - 0.0023 17.2 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KFX93455.1 - 0.0033 17.1 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.27 KFX93456.1 - 1.3e-46 158.5 0.2 9.5e-22 78.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFX93456.1 - 9.4e-20 70.4 5.3 9.4e-20 70.4 5.3 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KFX93456.1 - 2.5e-15 57.1 11.2 0.00021 21.2 0.0 4.6 3 2 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX93456.1 - 1.6e-11 44.1 3.2 0.00077 19.0 0.0 4.7 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX93456.1 - 1.9e-07 31.4 0.0 0.0017 18.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX93456.1 - 1e-05 25.1 0.3 0.18 11.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX93456.1 - 1.1e-05 26.1 16.4 0.02 15.4 0.0 4.7 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 KFX93456.1 - 1.1e-05 25.4 1.6 0.096 12.6 0.0 3.6 4 0 0 4 4 3 2 RsgA GTPase AAA_18 PF13238.6 KFX93456.1 - 1.3e-05 25.7 0.8 0.44 11.1 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KFX93456.1 - 1.5e-05 25.4 0.8 0.058 13.8 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 KFX93456.1 - 1.9e-05 24.9 0.1 0.4 10.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX93456.1 - 4.8e-05 23.2 1.2 0.0067 16.2 0.0 3.3 4 1 1 5 5 4 1 AAA domain MMR_HSR1 PF01926.23 KFX93456.1 - 0.00011 22.2 3.6 0.13 12.3 0.1 3.3 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_24 PF13479.6 KFX93456.1 - 0.00014 21.7 1.3 0.79 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KFX93456.1 - 0.00017 22.1 3.1 1 9.8 0.1 4.2 5 1 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFX93456.1 - 0.00041 20.4 0.3 1.9 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KFX93456.1 - 0.00093 19.2 0.3 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KFX93456.1 - 0.0013 18.5 15.3 0.27 10.9 0.0 5.0 4 1 1 5 5 5 2 AAA ATPase domain RNA_helicase PF00910.22 KFX93456.1 - 0.0023 18.3 0.0 3.9 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KFX93456.1 - 0.0059 16.7 4.9 9.2 6.3 0.0 4.1 4 0 0 4 4 4 0 Dynamin family AAA_28 PF13521.6 KFX93456.1 - 0.0062 16.8 9.2 0.25 11.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain MobB PF03205.14 KFX93456.1 - 0.0074 16.2 0.2 0.35 10.8 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFX93456.1 - 0.012 15.5 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KFX93456.1 - 0.02 13.9 2.6 2.6 6.9 0.0 3.0 3 1 1 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFX93456.1 - 0.031 13.8 0.0 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KFX93456.1 - 0.039 13.2 1.9 3.4 6.9 0.1 2.7 3 0 0 3 3 2 0 Zeta toxin SRP54 PF00448.22 KFX93456.1 - 0.045 13.4 0.3 6 6.4 0.3 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KFX93456.1 - 0.045 13.7 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFX93456.1 - 0.051 13.6 0.6 7.4 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KFX93456.1 - 0.061 13.0 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KFX93456.1 - 0.062 13.5 0.7 12 6.1 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KFX93456.1 - 0.066 12.8 3.8 1.4 8.5 0.6 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KFX93456.1 - 0.079 12.5 0.1 12 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX93456.1 - 0.083 12.1 0.0 16 4.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KFX93456.1 - 0.12 12.3 0.4 3.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain DUF87 PF01935.17 KFX93456.1 - 0.18 11.9 9.7 1.6 8.8 0.0 4.5 5 1 1 6 6 5 0 Helicase HerA, central domain AAA_17 PF13207.6 KFX93456.1 - 0.35 11.3 5.0 27 5.2 0.3 3.7 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KFX93456.1 - 0.37 10.3 8.3 5.2 6.6 0.0 4.2 6 0 0 6 6 5 0 AAA domain ATPase_2 PF01637.18 KFX93456.1 - 7.8 6.3 7.1 28 4.5 0.0 3.6 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea PD40 PF07676.12 KFX93459.1 - 0.13 12.2 0.8 7.7 6.6 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.6 KFX93459.1 - 0.17 11.7 1.5 16 5.5 0.1 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KFX93460.1 - 1.2e-05 25.1 0.2 2.6e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF2738 PF10927.8 KFX93460.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) ORC6 PF05460.13 KFX93460.1 - 0.2 10.9 4.2 0.29 10.3 4.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.32 KFX93461.1 - 5.9e-13 49.1 10.5 3e-05 24.7 0.7 4.3 3 2 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX93461.1 - 0.00078 19.7 1.2 0.012 15.9 0.7 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SPRY PF00622.28 KFX93462.1 - 3.1e-21 75.7 0.0 4.9e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BPD_transp_2 PF02653.16 KFX93462.1 - 0.016 14.4 0.9 0.024 13.8 0.9 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component zf-C3HC4 PF00097.25 KFX93470.1 - 0.18 11.7 7.2 0.39 10.6 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.14 KFX93479.1 - 9.8e-27 93.2 0.1 1.9e-26 92.3 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFX93479.1 - 2.7e-12 47.0 1.3 5.6e-12 46.0 1.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFX93479.1 - 6.5e-05 22.6 0.1 9.8e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KFX93479.1 - 0.0012 18.4 4.6 0.0023 17.4 4.6 1.7 1 1 0 1 1 1 1 NnrU protein Cupin_2 PF07883.11 KFX93506.1 - 3.5e-15 55.5 0.6 6.1e-15 54.7 0.2 1.6 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 KFX93506.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 KFX93506.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase EutQ PF06249.12 KFX93506.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Zn_clus PF00172.18 KFX93507.1 - 6.9e-09 35.7 10.3 1.2e-08 34.9 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX93507.1 - 0.00027 20.1 0.0 0.00065 18.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KFX93508.1 - 3.6e-29 102.0 0.2 4.9e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX93508.1 - 9.2e-21 74.6 0.0 1.4e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX93508.1 - 5e-08 32.7 0.1 1.6e-06 27.8 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFX93508.1 - 1.6e-06 28.4 0.0 3.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KFX93508.1 - 6e-06 25.5 0.1 1.9e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 KFX93508.1 - 0.0015 18.6 0.2 0.0035 17.4 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX93508.1 - 0.0016 18.6 0.3 0.0033 17.5 0.3 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KFX93508.1 - 0.0026 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 KFX93508.1 - 0.0038 17.4 0.1 0.057 13.6 0.0 2.5 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 KFX93508.1 - 0.0071 16.8 0.1 0.017 15.6 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFX93508.1 - 0.0094 15.1 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFX93508.1 - 0.011 14.8 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 KFX93508.1 - 0.036 14.7 2.1 0.23 12.1 0.4 2.4 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KFX93508.1 - 0.07 12.3 0.4 0.98 8.5 0.1 2.4 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein Kdo_hydroxy PF11004.8 KFX93508.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Pyr_redox PF00070.27 KFX93508.1 - 0.086 13.4 0.1 0.85 10.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX93508.1 - 0.11 11.8 1.6 0.23 10.7 1.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 KFX93508.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 L31 PF09784.9 KFX93509.1 - 0.049 14.0 0.1 1.1 9.8 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Abhydrolase_3 PF07859.13 KFX93510.1 - 8.8e-12 45.3 0.0 3.4e-05 23.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX93510.1 - 3.6e-07 29.4 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase La PF05383.17 KFX93511.1 - 3.6e-18 65.4 0.5 6.3e-18 64.6 0.5 1.4 1 0 0 1 1 1 1 La domain CwfJ_C_2 PF04676.14 KFX93518.1 - 1.6e-30 105.9 0.1 7.7e-30 103.7 0.1 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KFX93518.1 - 8e-28 96.8 0.0 1.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SET_assoc PF11767.8 KFX93518.1 - 0.14 11.8 0.0 0.47 10.1 0.0 1.9 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated ATP_bind_1 PF03029.17 KFX93519.1 - 2.3e-72 243.7 0.0 3.1e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFX93519.1 - 5.9e-06 25.5 0.0 0.012 14.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFX93519.1 - 6.4e-06 25.8 0.0 0.00083 18.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PRK PF00485.18 KFX93519.1 - 0.00025 20.9 0.0 0.00077 19.2 0.0 1.8 2 0 0 2 2 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KFX93519.1 - 0.00058 19.5 0.0 0.024 14.3 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFX93519.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFX93519.1 - 0.0006 20.1 0.0 0.0021 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX93519.1 - 0.00096 19.3 0.2 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KFX93519.1 - 0.0017 17.6 0.1 0.084 12.0 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit NACHT PF05729.12 KFX93519.1 - 0.0017 18.3 0.0 0.0072 16.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KFX93519.1 - 0.002 17.4 0.0 0.0057 15.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.23 KFX93519.1 - 0.002 18.2 0.0 0.016 15.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX93519.1 - 0.003 17.1 0.0 0.1 12.1 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFX93519.1 - 0.0036 17.7 0.0 0.0088 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain Arf PF00025.21 KFX93519.1 - 0.0046 16.4 0.0 1 8.8 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family Roc PF08477.13 KFX93519.1 - 0.0063 16.7 0.0 0.92 9.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KFX93519.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFX93519.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFX93519.1 - 0.01 15.4 0.0 0.73 9.4 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFX93519.1 - 0.021 14.7 0.0 6.7 6.6 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 KFX93519.1 - 0.059 13.1 0.1 0.41 10.4 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Methyltransf_32 PF13679.6 KFX93519.1 - 0.072 13.1 0.1 0.2 11.7 0.1 1.7 1 1 1 2 2 2 0 Methyltransferase domain Fes1 PF08609.10 KFX93533.1 - 1e-09 39.2 2.9 1e-09 39.2 2.9 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KFX93533.1 - 5.1e-08 32.7 0.1 0.0062 16.5 0.0 3.0 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFX93533.1 - 4e-06 26.6 0.0 0.01 16.0 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KFX93533.1 - 4.4e-06 27.1 0.2 0.00069 20.1 0.0 2.3 1 1 1 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KFX93533.1 - 5.9e-06 26.6 0.0 1.9e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 HEAT repeats DUF3535 PF12054.8 KFX93533.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) V-ATPase_H_C PF11698.8 KFX93533.1 - 0.043 13.9 0.0 0.099 12.8 0.0 1.6 1 1 0 1 1 1 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KFX93533.1 - 0.048 13.7 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 KFX93533.1 - 0.062 11.8 0.1 5.1 5.5 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Uso1_p115_head PF04869.14 KFX93533.1 - 0.1 11.7 0.4 3.7 6.6 0.1 2.6 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region DUF825 PF05695.12 KFX93533.1 - 0.14 9.3 0.0 0.17 9.0 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Ribosomal_L5_C PF00673.21 KFX93534.1 - 5.1e-27 93.9 0.0 8.7e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFX93534.1 - 1.8e-15 57.0 0.1 3.4e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 MIF4G_like PF09088.11 KFX93535.1 - 8.5e-91 302.9 0.1 1.3e-90 302.4 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KFX93535.1 - 4.6e-73 246.0 0.0 6.9e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KFX93535.1 - 0.032 13.9 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain 6PF2K PF01591.18 KFX93536.1 - 6.2e-57 192.5 0.0 8.7e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFX93536.1 - 7.1e-22 78.0 0.1 2.2e-21 76.4 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IstB_IS21 PF01695.17 KFX93536.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFX93536.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KFX93536.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.22 KFX93537.1 - 2.5e-86 289.5 0.5 2.8e-86 289.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Aminotran_4 PF01063.19 KFX93537.1 - 0.19 11.6 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Amino-transferase class IV DUF2181 PF10223.9 KFX93544.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) EMP24_GP25L PF01105.24 KFX93545.1 - 1.3e-40 139.3 0.0 1.4e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KFX93545.1 - 0.0067 14.7 1.2 0.0093 14.2 1.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CLZ PF16526.5 KFX93545.1 - 0.047 14.1 1.1 0.072 13.5 1.1 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 KFX93545.1 - 0.11 13.2 0.9 0.55 10.9 0.9 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DUF4665 PF15679.5 KFX93545.1 - 0.13 12.8 0.2 0.23 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) PhyH PF05721.13 KFX93551.1 - 3.4e-12 47.1 0.0 5.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KFX93566.1 - 3e-95 319.7 24.3 3.8e-95 319.4 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93566.1 - 1.5e-15 57.0 48.1 5.5e-09 35.4 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADK PF00406.22 KFX93574.1 - 2.7e-26 92.5 0.0 4e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KFX93574.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFX93574.1 - 5.4e-05 23.6 0.0 0.15 12.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain HopA1 PF17914.1 KFX93577.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 HopA1 effector protein family A_deamin PF02137.18 KFX93582.1 - 2.2e-32 112.8 0.0 2.8e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain zf-C6H2 PF15801.5 KFX93583.1 - 0.037 14.3 7.5 0.081 13.2 7.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF2203 PF09969.9 KFX93583.1 - 0.12 13.1 0.2 0.12 13.1 0.2 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) SF3b10 PF07189.11 KFX93584.1 - 6.3e-39 132.0 0.0 7.8e-39 131.7 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KFX93585.1 - 3.1e-62 210.1 0.0 5.2e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 MAGE family Rad21_Rec8_N PF04825.13 KFX93586.1 - 6.9e-33 113.1 0.0 1.3e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein MFS_1 PF07690.16 KFX93586.1 - 5e-32 111.2 28.6 7.8e-32 110.6 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Rad21_Rec8 PF04824.16 KFX93586.1 - 1e-05 24.7 0.0 2.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.12 KFX93587.1 - 3.3e-116 388.5 22.2 4.7e-116 388.0 22.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX93587.1 - 1.1e-16 61.4 0.1 3.3e-15 56.7 0.0 2.2 1 1 1 2 2 2 1 ML-like domain BTB PF00651.31 KFX93588.1 - 1.7e-29 102.3 0.1 1.1e-14 54.6 0.5 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KFX93588.1 - 4.1e-06 27.0 0.0 1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX93588.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93588.1 - 0.00013 22.4 0.1 0.00053 20.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX93588.1 - 0.00026 21.3 0.2 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 KFX93588.1 - 0.0017 18.5 0.1 0.0053 16.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 KFX93588.1 - 0.021 15.3 0.0 0.096 13.3 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Imm68 PF15583.6 KFX93588.1 - 0.033 14.4 3.7 0.32 11.2 3.7 2.3 1 1 0 1 1 1 0 Immunity protein 68 YqzH PF14164.6 KFX93588.1 - 2.5 8.3 4.5 64 3.7 0.0 3.0 3 0 0 3 3 3 0 YqzH-like protein Pkinase PF00069.25 KFX93589.1 - 1.1e-54 185.6 2.5 2.6e-34 118.8 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93589.1 - 1.8e-35 122.5 0.0 2.8e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX93589.1 - 0.0006 19.2 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX93589.1 - 0.061 12.1 3.3 0.69 8.6 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase DUF3896 PF13035.6 KFX93589.1 - 0.1 12.8 0.1 0.31 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) APH PF01636.23 KFX93589.1 - 0.3 11.0 1.2 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nbl1_Borealin_N PF10444.9 KFX93589.1 - 4 7.1 6.2 2.6 7.8 0.1 2.8 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF4644 PF15486.6 KFX93589.1 - 8.7 6.1 9.8 0.91 9.3 2.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4644) TolB_like PF15869.5 KFX93590.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like 4HBT_3 PF13622.6 KFX93591.1 - 7.9e-84 281.8 0.1 9.5e-84 281.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFX93591.1 - 5.7e-26 90.9 0.0 2.3e-10 40.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase MT0933_antitox PF14013.6 KFX93592.1 - 1.3 9.3 4.9 6.5 7.2 4.8 2.0 1 1 0 1 1 1 0 MT0933-like antitoxin protein Zip PF02535.22 KFX93592.1 - 9.4 5.3 5.4 11 5.1 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Oxysterol_BP PF01237.18 KFX93593.1 - 2e-133 444.8 1.0 7.5e-133 443.0 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KFX93593.1 - 7.9e-44 148.8 0.2 1.9e-43 147.6 0.2 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein GAT PF03127.14 KFX93593.1 - 3.4e-19 68.9 2.5 3.8e-17 62.3 0.9 2.8 2 0 0 2 2 2 1 GAT domain Ank_5 PF13857.6 KFX93593.1 - 3.1e-16 59.2 0.1 1e-08 35.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX93593.1 - 2.4e-14 53.0 1.2 0.00016 21.9 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KFX93593.1 - 2e-13 50.7 0.1 1.1e-08 35.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93593.1 - 1.6e-12 47.7 0.0 2.3e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KFX93593.1 - 1e-11 45.3 1.0 2.2e-11 44.2 1.0 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.6 KFX93593.1 - 2.8e-11 42.6 0.3 0.0013 19.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KFX93593.1 - 3.7e-07 30.3 1.1 1.3e-06 28.6 0.8 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFX93593.1 - 0.00014 22.2 3.6 0.0005 20.5 3.6 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain AGOG PF09171.10 KFX93593.1 - 0.0071 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 N-glycosylase/DNA lyase VHS PF00790.19 KFX93593.1 - 0.019 14.8 0.1 0.053 13.4 0.1 1.7 1 0 0 1 1 1 0 VHS domain UBA_4 PF14555.6 KFX93594.1 - 2.4e-11 43.3 0.3 4.9e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFX93594.1 - 1.3e-08 34.9 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.14 KFX93594.1 - 0.0031 16.8 1.3 0.0051 16.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) TAF4 PF05236.14 KFX93594.1 - 0.014 15.2 4.0 0.019 14.7 4.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Phage_Mu_F PF04233.14 KFX93594.1 - 1.4 9.7 6.5 3.3 8.5 6.5 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein Pan3_PK PF18101.1 KFX93595.1 - 1.3e-63 213.1 0.1 2.1e-63 212.4 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFX93595.1 - 3.4e-05 23.3 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Tis11B_N PF04553.12 KFX93595.1 - 0.07 13.7 0.7 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 Tis11B like protein, N terminus zf-CCCH PF00642.24 KFX93595.1 - 0.14 12.1 0.7 0.27 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1850 PF08905.11 KFX93596.1 - 0.039 14.3 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) Osmo_CC PF08946.10 KFX93596.1 - 0.23 11.7 2.5 0.6 10.4 0.3 2.2 1 1 1 2 2 2 0 Osmosensory transporter coiled coil tRNA-synt_2 PF00152.20 KFX93601.1 - 1.5e-30 106.4 0.0 1.7e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Tudor_FRX1 PF18336.1 KFX93602.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.5 1 1 0 1 1 1 0 Fragile X mental retardation Tudor domain ADH_zinc_N PF00107.26 KFX93603.1 - 2.5e-20 72.8 0.1 8.4e-20 71.1 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX93603.1 - 9.5e-16 59.1 0.1 2e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX93603.1 - 3.1e-09 36.7 0.0 9.6e-09 35.1 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Nairo_nucleo PF02477.15 KFX93603.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Nucleocapsid N protein CENP-S PF15630.6 KFX93604.1 - 2.5e-34 117.5 0.0 3.6e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFX93604.1 - 3e-07 30.5 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KFX93604.1 - 0.00083 19.3 0.0 0.0022 18.0 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KFX93604.1 - 0.034 14.5 0.3 0.054 13.8 0.0 1.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFX93604.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.8 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.16 KFX93604.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SAM_decarbox PF01536.16 KFX93610.1 - 9.1e-71 238.7 0.0 1e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase YkuI_C PF10388.9 KFX93611.1 - 0.28 11.0 0.3 0.64 9.8 0.1 1.6 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain Bud13 PF09736.9 KFX93617.1 - 1.6e-21 77.2 0.6 1.6e-21 77.2 0.6 2.7 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex HALZ PF02183.18 KFX93617.1 - 0.09 13.0 6.7 17 5.7 0.4 3.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Spc24 PF08286.11 KFX93617.1 - 2.3 8.5 6.3 0.63 10.3 1.5 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FtsL PF04999.13 KFX93617.1 - 4.2 7.4 9.8 2.5 8.2 0.2 3.3 2 1 0 2 2 2 0 Cell division protein FtsL SKA2 PF16740.5 KFX93617.1 - 8.1 6.3 10.7 0.29 10.9 0.8 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 AAA_18 PF13238.6 KFX93618.1 - 0.0034 17.9 0.1 0.079 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFX93618.1 - 0.005 15.9 0.1 0.0084 15.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PRK PF00485.18 KFX93618.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KFX93618.1 - 0.095 12.6 0.3 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.6 KFX93618.1 - 0.14 11.9 1.6 0.49 10.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KFX93618.1 - 0.18 12.3 0.1 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 ABC transporter Lipase_3 PF01764.25 KFX93619.1 - 0.0029 17.5 0.0 0.038 13.8 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) PUA_2 PF14306.6 KFX93635.1 - 3.3e-53 179.6 0.0 3.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 PUA-like domain bPH_6 PF10756.9 KFX93635.1 - 0.02 14.9 0.1 0.17 12.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial PH domain Complex1_LYR PF05347.15 KFX93636.1 - 6e-20 71.0 4.5 8.4e-20 70.6 4.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFX93636.1 - 2.6e-05 24.9 2.0 2.9e-05 24.7 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFX93636.1 - 0.021 15.4 0.4 0.024 15.2 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Glutaredoxin2_C PF04399.13 KFX93636.1 - 0.086 12.7 0.4 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ADH_zinc_N PF00107.26 KFX93638.1 - 4.9e-29 100.9 0.2 7.6e-29 100.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX93638.1 - 9.7e-18 65.5 0.1 1.8e-17 64.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFX93638.1 - 0.0023 17.4 0.5 0.0036 16.8 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 KFX93638.1 - 0.0027 17.6 0.3 0.096 12.6 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain APG6_N PF17675.1 KFX93658.1 - 0.0026 18.3 8.1 0.003 18.1 8.1 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region ExsD PF16806.5 KFX93658.1 - 0.0087 16.0 2.9 0.01 15.8 2.9 1.1 1 0 0 1 1 1 1 Antiactivator protein ExsD TMF_TATA_bd PF12325.8 KFX93658.1 - 0.012 15.8 8.6 0.016 15.4 8.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LpqV PF17301.2 KFX93658.1 - 0.086 13.1 0.8 1.5 9.1 0.1 2.2 1 1 1 2 2 2 0 Putative lipoprotein LpqV FapA PF03961.13 KFX93658.1 - 0.14 10.7 3.0 0.15 10.6 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KFX93658.1 - 3.9 7.3 12.1 4.3 7.2 2.8 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 KFX93658.1 - 7.7 6.7 15.2 0.18 11.9 6.8 2.1 1 1 1 2 2 2 0 Basic region leucine zipper APG6_N PF17675.1 KFX93660.1 - 0.004 17.7 6.7 0.0044 17.6 6.7 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 KFX93660.1 - 0.032 14.5 8.8 0.047 13.9 8.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LpqV PF17301.2 KFX93660.1 - 0.13 12.5 0.5 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 Putative lipoprotein LpqV Phlebovirus_NSM PF07246.11 KFX93660.1 - 0.18 11.1 5.7 0.23 10.8 5.7 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.15 KFX93660.1 - 3.6 7.4 10.6 2.7 7.8 1.3 2.3 1 1 1 2 2 2 0 Septum formation initiator RVT_1 PF00078.27 KFX93667.1 - 8.2e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DapH_N PF08503.10 KFX93667.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Cytomega_UL20A PF05984.12 KFX93668.1 - 0.15 12.3 0.1 0.22 11.8 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein ZZ PF00569.17 KFX93669.1 - 2.5e-11 43.2 6.2 4.5e-11 42.4 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 KFX93669.1 - 2.8e-07 30.9 2.5 0.00041 20.7 0.4 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KFX93669.1 - 5.9e-07 28.6 13.7 7.3e-05 22.0 0.6 3.8 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KFX93669.1 - 1.3e-06 27.9 5.5 7e-05 22.4 0.9 3.4 3 0 0 3 3 3 1 EF-hand domain C1_2 PF03107.16 KFX93669.1 - 0.00085 19.6 2.2 0.0015 18.8 2.2 1.4 1 0 0 1 1 1 1 C1 domain Mu-transpos_C PF09299.11 KFX93669.1 - 0.013 15.4 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 Mu transposase, C-terminal EF-hand_8 PF13833.6 KFX93669.1 - 0.015 15.2 1.2 0.98 9.3 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain pair zf-B_box PF00643.24 KFX93669.1 - 0.052 13.7 5.0 0.11 12.7 5.0 1.5 1 0 0 1 1 1 0 B-box zinc finger DUF2335 PF10097.9 KFX93669.1 - 0.073 13.0 0.1 0.26 11.3 0.1 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Dockerin_1 PF00404.18 KFX93669.1 - 0.08 13.2 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Dockerin type I domain EF-hand_5 PF13202.6 KFX93669.1 - 0.31 10.6 5.8 0.12 11.9 0.8 2.8 3 0 0 3 3 3 0 EF hand GATA PF00320.27 KFX93669.1 - 5 6.8 5.4 2.2 7.9 0.1 3.0 2 0 0 2 2 2 0 GATA zinc finger Diphthamide_syn PF01866.17 KFX93671.1 - 2.2e-87 293.3 0.0 2.8e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein RTA1 PF04479.13 KFX93672.1 - 1.3e-69 233.9 9.6 1.3e-69 233.9 9.6 1.5 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 KFX93673.1 - 8.9e-08 32.1 10.7 1.8e-07 31.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX93673.1 - 0.013 14.3 0.2 0.019 13.8 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Prot_inhib_II PF02428.15 KFX93673.1 - 1.1 9.8 8.3 3.3 8.2 8.2 1.9 1 1 0 1 1 1 0 Potato type II proteinase inhibitor family Abhydrolase_1 PF00561.20 KFX93674.1 - 7.2e-14 52.1 0.0 4.5e-13 49.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX93674.1 - 3.9e-12 45.9 0.0 1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX93674.1 - 7.3e-11 43.1 0.4 7.3e-11 43.1 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFX93674.1 - 0.002 17.6 0.6 0.3 10.5 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Glyco_hydro_32N PF00251.20 KFX93674.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KFX93674.1 - 0.021 14.2 1.3 0.036 13.4 1.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 UPF0227 PF05728.12 KFX93674.1 - 0.094 12.6 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KFX93674.1 - 0.099 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 KFX93674.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein EST1 PF10374.9 KFX93675.1 - 0.078 13.6 0.0 0.087 13.5 0.0 1.2 1 0 0 1 1 1 0 Telomerase activating protein Est1 JSRP PF15312.6 KFX93675.1 - 0.08 12.9 0.4 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Kelch_5 PF13854.6 KFX93676.1 - 9.2e-10 38.3 1.5 2.1e-06 27.6 0.3 3.7 3 0 0 3 3 3 2 Kelch motif VSP PF03302.13 KFX93676.1 - 0.0033 16.3 0.2 0.0051 15.7 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Adeno_E3_CR1 PF02440.15 KFX93676.1 - 0.17 11.7 2.5 0.19 11.5 1.0 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 FAD_binding_4 PF01565.23 KFX93678.1 - 3.5e-23 81.9 0.0 5.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX93678.1 - 0.0061 16.6 0.1 0.024 14.7 0.1 2.1 1 0 0 1 1 1 1 Berberine and berberine like EstA_Ig_like PF18435.1 KFX93678.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain COesterase PF00135.28 KFX93679.1 - 2.2e-57 195.1 0.0 1.1e-56 192.8 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX93679.1 - 1.2e-07 31.8 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX93679.1 - 0.031 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KFX93679.1 - 0.096 11.5 0.1 0.56 9.0 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Fungal_trans_2 PF11951.8 KFX93680.1 - 9.6e-07 27.9 0.3 1.3e-06 27.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1175 PF06672.11 KFX93681.1 - 0.0048 16.6 0.1 0.0087 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) Glyco_hydro_43 PF04616.14 KFX93682.1 - 5.6e-67 226.1 0.9 7.1e-67 225.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX93682.1 - 5.8e-16 58.8 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sbt_1 PF05982.12 KFX93690.1 - 1.3 8.2 24.8 0.29 10.3 20.0 1.9 1 1 1 2 2 2 0 Na+-dependent bicarbonate transporter superfamily TCR_zetazeta PF11628.8 KFX93690.1 - 4.5 7.0 5.9 21 4.9 0.1 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Collagen PF01391.18 KFX93701.1 - 0.05 13.4 5.6 0.1 12.4 5.6 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) zf-C2H2_4 PF13894.6 KFX93712.1 - 0.017 15.9 0.1 0.045 14.6 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger CpXC PF14353.6 KFX93712.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 CpXC protein MtrG PF04210.13 KFX93712.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Lyase_1 PF00206.20 KFX93722.1 - 7e-59 199.8 0.0 8.3e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Lyase GHMP_kinases_N PF00288.26 KFX93723.1 - 0.0003 21.0 0.1 0.0019 18.4 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain LPMO_10 PF03067.15 KFX93724.1 - 0.038 14.6 0.4 0.32 11.6 0.4 2.0 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cu-oxidase_2 PF07731.14 KFX93725.1 - 1.9e-25 89.2 1.4 1.9e-24 86.0 0.3 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFX93725.1 - 9.6e-22 77.2 0.6 3.3e-21 75.5 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX93725.1 - 0.0052 16.9 0.0 0.52 10.4 0.0 2.8 2 1 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.18 KFX93726.1 - 3e-05 24.0 9.3 5.1e-05 23.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF3m_C_helix PF18005.1 KFX93726.1 - 0.1 12.3 4.3 0.065 12.9 0.7 2.2 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix RTA1 PF04479.13 KFX93728.1 - 2.4e-45 154.7 11.5 3.4e-45 154.2 11.5 1.1 1 0 0 1 1 1 1 RTA1 like protein AMP-binding PF00501.28 KFX93729.1 - 1.1e-295 979.6 0.0 2.2e-74 250.6 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KFX93729.1 - 2e-198 659.7 0.0 2.5e-58 197.8 0.0 6.2 5 1 0 5 5 5 5 Condensation domain p450 PF00067.22 KFX93729.1 - 5.6e-54 183.6 0.0 9.4e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.25 KFX93729.1 - 1.2e-46 156.9 5.1 3.6e-12 46.5 0.0 5.8 5 0 0 5 5 5 4 Phosphopantetheine attachment site Chromo PF00385.24 KFX93729.1 - 0.00016 21.5 0.6 0.00037 20.3 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AMP-binding_C PF13193.6 KFX93729.1 - 0.00039 21.3 0.0 9.2 7.3 0.0 4.5 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain TACC_C PF05010.14 KFX93729.1 - 0.45 10.3 1.0 0.64 9.8 0.1 1.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AATase PF07247.12 KFX93730.1 - 3.6e-09 35.7 0.1 1.4e-05 23.8 0.0 3.1 3 0 0 3 3 3 3 Alcohol acetyltransferase GNVR PF13807.6 KFX93730.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase NUMOD4 PF07463.11 KFX93730.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 NUMOD4 motif DIOX_N PF14226.6 KFX93731.1 - 1.6e-23 83.7 0.0 2.7e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX93731.1 - 2.4e-07 31.2 0.0 4.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF218 PF02698.17 KFX93731.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain CorA PF01544.18 KFX93732.1 - 0.0028 17.0 0.0 0.0065 15.8 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Glucokinase PF02685.16 KFX93732.1 - 0.036 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Glucokinase Glyco_hydro_7 PF00840.20 KFX93735.1 - 1.3e-199 663.4 19.9 1.5e-199 663.2 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Alginate_lyase2 PF08787.11 KFX93736.1 - 1.9e-41 142.5 0.0 2.2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Alginate_lyase PF05426.12 KFX93738.1 - 5.3e-13 49.1 2.8 6e-12 45.7 2.8 2.1 1 1 0 1 1 1 1 Alginate lyase Cerato-platanin PF07249.12 KFX93739.1 - 3.1e-49 166.0 0.9 3.5e-49 165.8 0.9 1.0 1 0 0 1 1 1 1 Cerato-platanin FOG_N PF15888.5 KFX93739.1 - 0.11 12.8 0.0 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 Folded gastrulation N-terminus Pkinase PF00069.25 KFX93740.1 - 8.1e-69 231.9 0.1 1.5e-67 227.8 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 KFX93740.1 - 1.1e-37 128.4 0.1 2e-37 127.5 0.1 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KFX93740.1 - 1.9e-34 119.1 0.1 3.1e-33 115.1 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX93740.1 - 3e-06 26.7 0.0 6.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX93740.1 - 0.00084 18.4 0.1 0.0018 17.3 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFX93740.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX93740.1 - 0.0043 17.0 0.1 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX93740.1 - 0.0053 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFX93740.1 - 0.01 15.4 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MSA-2c PF12238.8 KFX93740.1 - 1.7 8.6 5.9 4.6 7.2 5.9 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c SMC_N PF02463.19 KFX93741.1 - 1.2e-26 93.5 0.0 2.2e-26 92.6 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX93741.1 - 1.6e-17 64.7 0.2 1.6e-17 64.7 0.2 4.7 3 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 KFX93741.1 - 7.2e-11 42.4 0.0 4.1e-07 30.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFX93741.1 - 1.9e-07 31.2 0.2 0.0014 18.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX93741.1 - 0.0004 20.1 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KFX93741.1 - 0.057 13.8 0.8 0.22 12.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KFX93741.1 - 0.23 11.0 0.0 0.23 11.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KFX93741.1 - 0.54 10.8 0.0 0.54 10.8 0.0 4.6 3 2 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 KFX93741.1 - 0.68 10.3 0.0 0.68 10.3 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Sec34 PF04136.15 KFX93741.1 - 0.96 9.3 18.1 0.064 13.1 1.5 4.8 3 2 1 4 4 4 0 Sec34-like family Cyto_heme_lyase PF01265.17 KFX93753.1 - 1.1e-43 149.9 3.2 3.5e-42 145.0 3.2 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase tRNA-synt_1g PF09334.11 KFX93754.1 - 4.9e-145 483.2 0.2 1.1e-144 482.1 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFX93754.1 - 4.9e-05 21.8 0.2 0.18 10.0 0.0 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.24 KFX93754.1 - 0.11 12.7 1.8 0.23 11.7 1.8 1.5 1 0 0 1 1 1 0 Laminin EGF domain Yae1_N PF09811.9 KFX93755.1 - 3.5e-10 39.4 4.8 5.5e-10 38.8 4.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Glyco_hydro_7 PF00840.20 KFX93759.1 - 1.8e-136 455.3 5.5 3.4e-135 451.1 5.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_20 PF00686.19 KFX93760.1 - 5.7e-32 109.5 0.7 9.4e-32 108.8 0.7 1.3 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KFX93760.1 - 2e-09 38.4 3.0 2e-09 38.4 1.9 1.6 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4774 PF15999.5 KFX93760.1 - 0.09 12.6 4.8 0.2 11.5 4.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4774) PAD PF03068.15 KFX93763.1 - 4e-117 391.5 0.0 4.6e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Inhibitor_I66 PF16850.5 KFX93764.1 - 2.7e-29 101.9 0.0 3.4e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Fungal_trans_2 PF11951.8 KFX93765.1 - 6.8e-30 104.1 3.5 8.8e-30 103.8 3.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93765.1 - 6.5e-05 23.0 8.8 0.00013 22.0 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KFX93766.1 - 2.4e-12 46.8 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX93766.1 - 0.00084 19.5 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFX93766.1 - 0.021 14.9 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 KFX93766.1 - 0.041 12.9 0.1 4.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFX93766.1 - 0.063 13.2 0.1 0.14 12.1 0.2 1.5 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 KFX93766.1 - 0.16 11.4 0.0 0.66 9.4 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AA_permease_2 PF13520.6 KFX93767.1 - 7e-81 272.2 23.4 8.8e-81 271.9 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX93767.1 - 6.4e-12 44.8 24.7 8.5e-12 44.4 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL PF00657.22 KFX93769.1 - 0.00052 20.1 0.2 0.00068 19.7 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFX93769.1 - 0.00077 19.9 0.1 0.0024 18.3 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AA_permease_2 PF13520.6 KFX93770.1 - 1.3e-54 185.7 54.6 1.5e-54 185.5 54.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX93770.1 - 1e-16 60.6 41.6 1.3e-16 60.2 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 KFX93771.1 - 2.3e-154 514.3 0.0 3.2e-154 513.8 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFX93771.1 - 4.4e-19 68.8 0.0 9.6e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFX93771.1 - 2.7e-13 49.9 0.1 6.4e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FSH1 PF03959.13 KFX93772.1 - 3.5e-23 82.4 0.0 1.4e-22 80.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FhuF PF06276.12 KFX93773.1 - 2.8e-18 66.9 0.0 5.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 KFX93773.1 - 2.2e-17 63.4 0.6 2.8e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 IucA / IucC family TauD PF02668.16 KFX93774.1 - 9.6e-31 107.5 0.0 1.5e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFX93774.1 - 0.0092 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 CsiD Peptidase_S8 PF00082.22 KFX93775.1 - 8.5e-36 123.7 10.3 2.2e-35 122.4 10.3 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFX93775.1 - 2.9e-09 37.5 0.6 5.4e-09 36.6 0.6 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SNF2_N PF00176.23 KFX93776.1 - 9.3e-56 189.0 0.0 1.7e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX93776.1 - 3.5e-14 53.1 0.0 7.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KFX93776.1 - 7.5e-06 25.7 6.8 1.5e-05 24.8 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX93776.1 - 1.6e-05 24.6 4.6 3.4e-05 23.6 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX93776.1 - 2.7e-05 23.9 4.6 2.7e-05 23.9 4.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX93776.1 - 4.9e-05 23.2 6.5 0.0001 22.2 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX93776.1 - 0.00026 21.1 7.4 0.00056 20.0 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFX93776.1 - 0.0003 20.8 3.9 0.00085 19.3 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFX93776.1 - 0.00062 20.1 6.7 0.00062 20.1 6.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX93776.1 - 0.0016 18.3 9.1 0.0041 16.9 9.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFX93776.1 - 0.0016 18.3 1.0 0.0035 17.2 1.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KFX93776.1 - 0.31 11.4 3.2 0.76 10.1 3.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFX93776.1 - 0.6 10.3 3.2 1.4 9.1 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 adh_short PF00106.25 KFX93777.1 - 1.8e-15 56.9 0.0 3.1e-13 49.6 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX93777.1 - 5.7e-08 32.6 0.0 7.9e-07 28.9 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX93777.1 - 1.7e-07 31.3 0.0 7.3e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFX93777.1 - 1.4e-06 28.0 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF577 PF04510.12 KFX93777.1 - 0.3 11.0 1.9 0.69 9.8 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF577) G-patch PF01585.23 KFX93778.1 - 1.5e-10 40.8 0.2 3.2e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFX93778.1 - 0.0039 17.2 0.3 0.0039 17.2 0.3 2.5 2 0 0 2 2 2 1 G-patch domain PRK PF00485.18 KFX93779.1 - 2.9e-57 193.6 0.0 5.8e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KFX93779.1 - 7.8e-40 136.5 0.0 1.4e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 KFX93779.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KFX93779.1 - 0.003 18.1 0.0 0.003 18.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFX93779.1 - 0.017 15.7 0.5 0.068 13.7 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KFX93779.1 - 0.049 13.8 0.0 0.28 11.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KFX93779.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 KFX93779.1 - 0.077 12.1 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP-bdg_M PF16360.5 KFX93779.1 - 0.75 10.4 6.0 2.2 9.0 6.0 1.7 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Kei1 PF08552.11 KFX93780.1 - 1.6e-64 217.4 5.9 1.6e-64 217.4 5.9 1.4 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 TRAM1 PF08390.11 KFX93780.1 - 0.013 15.1 0.6 0.03 14.0 0.6 1.6 1 0 0 1 1 1 0 TRAM1-like protein SPC12 PF06645.13 KFX93780.1 - 5.4 7.2 8.5 0.3 11.2 2.4 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Nop53 PF07767.11 KFX93781.1 - 1.2e-106 357.5 28.1 1.5e-106 357.1 28.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.22 KFX93782.1 - 2.6e-59 199.4 0.3 3.4e-59 199.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX93782.1 - 1.1e-36 125.7 0.1 1.8e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX93782.1 - 7.5e-18 64.6 0.2 9.2e-18 64.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX93782.1 - 2.8e-06 27.0 0.1 1.8e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX93782.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFX93782.1 - 4.5e-05 23.0 0.0 6.3e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFX93782.1 - 5.6e-05 22.6 0.3 7.2e-05 22.2 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFX93782.1 - 0.00027 20.9 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TIR_2 PF13676.6 KFX93782.1 - 0.076 13.6 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain NIR_SIR PF01077.22 KFX93783.1 - 1.1e-54 184.2 0.1 1.2e-48 164.6 0.1 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KFX93783.1 - 6.1e-30 102.9 0.1 2.7e-14 52.8 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KFX93783.1 - 2.2e-25 89.5 0.0 4.5e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KFX93783.1 - 2.1e-07 30.9 0.1 4.8e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KFX93783.1 - 0.0078 16.5 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II F1F0-ATPsyn_F PF10791.9 KFX93785.1 - 2.4e-42 143.3 0.2 2.9e-42 143.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KFX93785.1 - 0.0015 18.9 0.1 0.0022 18.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 KFX93786.1 - 4.2e-36 123.1 2.9 1e-35 121.8 1.5 1.9 2 0 0 2 2 2 1 ETC complex I subunit conserved region Aminotran_1_2 PF00155.21 KFX93787.1 - 2.1e-21 76.5 0.0 2.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX93787.1 - 0.0012 17.7 0.0 0.016 14.0 0.0 2.4 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase MCM PF00493.23 KFX93788.1 - 1.8e-103 344.5 0.3 2.7e-103 343.9 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFX93788.1 - 1.8e-39 134.5 0.3 3.2e-39 133.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KFX93788.1 - 8.5e-30 103.2 0.2 1.6e-29 102.2 0.2 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KFX93788.1 - 9.8e-25 86.8 0.1 2.6e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFX93788.1 - 2.3e-24 86.0 0.3 8.4e-24 84.2 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFX93788.1 - 6.9e-08 32.1 0.0 7.1e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFX93788.1 - 0.00092 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFX93788.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KFX93788.1 - 0.0068 16.4 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CDC27 PF09507.10 KFX93789.1 - 5.4e-80 269.9 15.2 1.2e-79 268.7 15.2 1.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 KFX93790.1 - 1e-177 591.2 0.0 1.2e-177 591.0 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MOZ_SAS PF01853.18 KFX93791.1 - 3e-81 271.4 0.1 4.5e-81 270.8 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFX93791.1 - 9.5e-23 79.6 0.6 1.8e-22 78.7 0.6 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFX93791.1 - 4.5e-18 64.9 0.0 1.2e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFX93791.1 - 0.00021 21.7 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93791.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_T PF00929.24 KFX93792.1 - 1.3e-18 68.1 0.0 2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFX93792.1 - 2e-05 24.4 0.0 6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease RNase_H2_suC PF08615.11 KFX93793.1 - 9.5e-24 84.2 0.0 1.7e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-C3HC4_2 PF13923.6 KFX93793.1 - 1.3e-09 37.8 16.1 4.5e-09 36.0 12.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX93793.1 - 1.9e-07 30.8 13.4 8.9e-07 28.7 10.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX93793.1 - 6.2e-07 29.2 12.5 6.2e-07 29.2 12.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX93793.1 - 3e-06 27.1 14.6 6e-06 26.1 12.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX93793.1 - 4.1e-06 26.7 11.9 4.1e-06 26.7 11.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KFX93793.1 - 7.7e-06 25.7 5.6 8.4e-06 25.6 3.9 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.15 KFX93793.1 - 1e-05 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.6 KFX93793.1 - 2.1e-05 24.6 11.9 2.1e-05 24.6 11.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFX93793.1 - 2.5e-05 24.0 12.2 0.0021 17.9 10.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SAP PF02037.27 KFX93793.1 - 5.4e-05 22.8 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 KFX93793.1 - 6.9e-05 23.1 12.1 6.9e-05 23.1 12.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 KFX93793.1 - 0.00066 19.8 5.2 0.0015 18.6 5.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFX93793.1 - 0.0019 18.4 6.7 0.0019 18.4 6.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFX93793.1 - 0.08 12.8 13.2 0.03 14.1 9.0 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain PARM PF17061.5 KFX93793.1 - 0.32 11.1 5.6 0.044 13.9 1.0 1.8 2 0 0 2 2 2 0 PARM Mob_synth_C PF06463.13 KFX93793.1 - 0.9 9.5 3.4 2.2 8.2 3.4 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Snf7 PF03357.21 KFX93794.1 - 7.1e-19 68.0 13.1 1.5e-18 67.0 12.8 1.6 1 1 1 2 2 2 1 Snf7 CK2S PF15011.6 KFX93794.1 - 0.017 15.0 5.6 1.2 9.0 2.0 2.6 1 1 0 2 2 2 0 Casein Kinase 2 substrate Baculo_PEP_C PF04513.12 KFX93794.1 - 0.086 12.9 2.2 5.2 7.1 0.4 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GOLD_2 PF13897.6 KFX93794.1 - 0.82 10.2 2.9 2.2 8.8 2.9 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF948 PF06103.11 KFX93794.1 - 1.2 9.4 11.0 12 6.3 0.3 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BCAS2 PF05700.11 KFX93794.1 - 1.6 8.4 9.8 0.65 9.7 5.4 2.4 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) CorA PF01544.18 KFX93794.1 - 7.2 5.8 7.2 1.1 8.5 2.1 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TRAPPC-Trs85 PF12739.7 KFX93795.1 - 7.6e-114 380.8 0.0 1e-113 380.4 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.20 KFX93797.1 - 6e-26 91.3 0.1 1.3e-25 90.3 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFX93797.1 - 6.5e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Tti2 PF10521.9 KFX93798.1 - 2.3e-79 266.9 1.0 2.7e-79 266.6 0.4 1.4 2 0 0 2 2 2 1 Tti2 family DNA_ligase_A_N PF04675.14 KFX93798.1 - 0.032 14.6 0.0 5.1 7.4 0.0 2.4 2 0 0 2 2 2 0 DNA ligase N terminus Syja_N PF02383.18 KFX93799.1 - 1.4e-71 241.5 0.0 3e-70 237.1 0.0 2.3 1 1 0 1 1 1 1 SacI homology domain RRM_1 PF00076.22 KFX93800.1 - 7.7e-26 89.7 1.2 2.6e-13 49.6 0.3 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX93800.1 - 1.3e-05 24.8 0.0 0.00051 19.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFX93800.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 KFX93800.1 - 0.078 13.2 0.4 0.078 13.2 0.4 3.3 2 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 KFX93801.1 - 3.6e-71 239.1 1.4 4.4e-71 238.8 1.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 KFX93801.1 - 0.028 14.5 1.4 0.58 10.2 0.2 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 KFX93801.1 - 0.03 13.9 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 KFX93801.1 - 0.16 12.2 3.1 0.85 9.9 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TPR_14 PF13428.6 KFX93802.1 - 5.4e-14 51.7 9.2 0.52 11.3 0.1 10.5 9 1 1 10 10 10 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFX93802.1 - 9.5e-08 32.1 9.3 0.19 11.7 0.1 6.8 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KFX93802.1 - 1.2e-07 31.3 2.9 0.23 11.8 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX93802.1 - 2.6e-07 30.1 1.2 0.00011 21.5 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 KFX93802.1 - 6.8e-07 29.6 4.6 0.45 10.5 0.1 4.9 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KFX93802.1 - 1.7e-06 28.2 2.9 2.6 8.4 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93802.1 - 0.0001 22.2 12.0 1.2 9.4 0.1 6.6 8 0 0 8 8 6 2 Tetratricopeptide repeat SNAP PF14938.6 KFX93802.1 - 0.00081 18.9 0.7 4.1 6.7 0.0 4.5 5 1 1 6 6 6 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 KFX93802.1 - 0.0019 18.7 2.3 1.9 9.1 0.0 5.2 6 1 0 6 6 4 1 Tetratricopeptide repeat RPN7 PF10602.9 KFX93802.1 - 0.0032 17.2 0.0 0.41 10.3 0.0 3.5 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 KFX93802.1 - 0.0038 17.0 9.7 7.8 6.5 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KFX93802.1 - 0.038 13.1 10.2 0.47 9.5 0.3 5.2 3 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 KFX93802.1 - 0.049 14.0 1.9 6.6 7.4 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX93802.1 - 0.17 12.6 3.5 16 6.4 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat ABC_membrane PF00664.23 KFX93813.1 - 9.8e-90 300.9 18.8 1.2e-49 169.5 8.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX93813.1 - 8e-44 149.5 0.0 2.8e-28 99.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX93813.1 - 1.2e-13 51.1 0.6 2.7e-09 36.8 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX93813.1 - 4.1e-07 30.4 4.9 0.022 15.0 0.2 3.5 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KFX93813.1 - 1.7e-06 27.6 2.2 0.05 13.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX93813.1 - 7e-06 26.0 0.1 0.033 14.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KFX93813.1 - 7.9e-06 25.6 0.2 0.12 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KFX93813.1 - 1.3e-05 25.6 2.8 0.095 13.1 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KFX93813.1 - 2e-05 24.6 0.8 0.26 11.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KFX93813.1 - 0.00023 21.2 0.2 2 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFX93813.1 - 0.00032 21.3 0.2 0.96 10.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KFX93813.1 - 0.0023 17.5 0.2 1.3 8.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFX93813.1 - 0.0024 18.1 0.2 0.74 10.0 0.2 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX93813.1 - 0.0043 17.1 1.4 0.28 11.3 0.1 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KFX93813.1 - 0.0062 17.1 4.3 0.21 12.1 0.6 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX93813.1 - 0.0078 15.9 3.2 2.8 7.6 0.3 3.1 2 1 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KFX93813.1 - 0.0094 15.0 0.1 2.4 7.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) RNA_helicase PF00910.22 KFX93813.1 - 0.0099 16.3 0.1 3 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFX93813.1 - 0.016 14.9 2.5 0.79 9.4 0.3 2.5 2 1 0 2 2 2 0 AAA domain DUF2178 PF09946.9 KFX93813.1 - 0.017 15.3 1.3 0.15 12.3 0.0 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) APS_kinase PF01583.20 KFX93813.1 - 0.028 14.3 1.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KFX93813.1 - 0.033 13.9 0.6 8.5 6.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 KFX93813.1 - 0.041 12.7 0.7 0.11 11.3 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DEAD PF00270.29 KFX93813.1 - 0.042 13.6 0.4 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_15 PF13175.6 KFX93813.1 - 0.044 13.5 0.3 10 5.7 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 KFX93813.1 - 0.048 12.7 0.7 5 6.1 0.2 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 KFX93813.1 - 0.062 13.4 0.0 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KFX93813.1 - 0.097 11.9 0.2 5.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 KFX93813.1 - 0.1 11.9 0.1 1.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 KFX93813.1 - 0.11 12.1 0.3 6 6.5 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KFX93813.1 - 0.12 11.8 4.2 11 5.2 0.3 3.8 5 0 0 5 5 4 0 FtsK/SpoIIIE family PRK PF00485.18 KFX93813.1 - 0.2 11.3 0.6 8.1 6.1 0.3 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PhoH PF02562.16 KFX93813.1 - 0.6 9.5 5.8 8.5 5.8 0.1 3.4 4 0 0 4 4 4 0 PhoH-like protein DUF87 PF01935.17 KFX93813.1 - 0.63 10.1 6.6 8.1 6.5 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Polysacc_synt_4 PF04669.13 KFX93815.1 - 3.9e-22 78.7 1.1 1.1e-20 74.0 1.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.9 KFX93815.1 - 0.0057 15.9 1.0 0.0066 15.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) Sugar_tr PF00083.24 KFX93820.1 - 1.7e-128 429.3 24.7 2e-128 429.1 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93820.1 - 5.1e-21 75.0 41.1 2.2e-17 63.0 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 KFX93821.1 - 6e-10 40.0 0.0 1.2e-09 39.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3_C PF01915.22 KFX93822.1 - 4.5e-65 219.4 0.0 1.5e-64 217.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX93822.1 - 1.5e-53 182.2 0.0 3.5e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX93822.1 - 6e-22 77.5 1.8 2.6e-21 75.5 0.3 2.8 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KFX93822.1 - 3.8e-18 65.7 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Cation_efflux PF01545.21 KFX93823.1 - 1.6e-45 155.3 15.8 1.6e-45 155.3 15.8 2.4 2 1 0 2 2 2 1 Cation efflux family DUF202 PF02656.15 KFX93823.1 - 3.1e-15 56.3 0.3 3.1e-15 56.3 0.3 3.6 4 1 1 5 5 5 1 Domain of unknown function (DUF202) ZT_dimer PF16916.5 KFX93823.1 - 0.014 15.5 0.1 0.034 14.3 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter Sugar_tr PF00083.24 KFX93824.1 - 6.2e-126 420.9 25.4 7.1e-126 420.7 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93824.1 - 4.8e-25 88.2 58.5 1.3e-23 83.5 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KFX93824.1 - 0.022 15.3 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3522 PF12036.8 KFX93824.1 - 0.79 10.0 9.6 0.35 11.1 2.2 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF3522) DUF4131 PF13567.6 KFX93824.1 - 0.88 9.2 10.4 5.3 6.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Glyco_hydro_79C PF16862.5 KFX93825.1 - 2.5e-17 63.7 1.5 3.8e-17 63.1 0.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain GIT_SHD PF08518.11 KFX93826.1 - 1e-25 89.0 3.8 6.3e-13 48.1 0.9 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Nup188_C PF18378.1 KFX93826.1 - 0.047 12.5 0.1 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain HCMV_UL139 PF12507.8 KFX93826.1 - 0.069 13.5 2.9 1.2 9.6 1.2 2.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF883 PF05957.13 KFX93826.1 - 0.092 13.4 0.3 0.092 13.4 0.3 5.3 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) GIT1_C PF12205.8 KFX93826.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.3 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term THP2 PF09432.10 KFX93826.1 - 0.25 11.4 6.2 0.13 12.3 0.9 2.7 2 0 0 2 2 2 0 Tho complex subunit THP2 Syntaxin_2 PF14523.6 KFX93826.1 - 0.55 10.6 17.8 0.03 14.7 1.7 4.4 3 1 1 4 4 4 0 Syntaxin-like protein CLZ PF16526.5 KFX93826.1 - 1.1 9.7 21.6 1.6 9.1 0.3 4.9 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KFX93826.1 - 1.9 9.0 11.5 0.58 10.7 0.3 4.6 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Collagen_mid PF15984.5 KFX93826.1 - 2.3 7.9 4.3 0.98 9.1 1.5 1.7 2 0 0 2 2 2 0 Bacterial collagen, middle region DUF4407 PF14362.6 KFX93826.1 - 2.4 7.4 31.7 0.12 11.7 18.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KFX93826.1 - 3.2 8.1 12.0 3.3 8.0 0.1 4.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 KFX93826.1 - 4.4 7.1 33.9 0.034 13.9 3.9 3.2 3 0 0 3 3 3 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 KFX93826.1 - 7.3 7.0 16.0 2 8.8 0.4 4.6 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ssu72 PF04722.13 KFX93827.1 - 8e-84 280.0 0.0 9.2e-84 279.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 KFX93828.1 - 3.3e-09 36.2 0.0 5.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX93828.1 - 3.5e-07 30.0 0.1 7.3e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX93828.1 - 2.2e-05 24.1 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NMU PF02070.15 KFX93828.1 - 0.098 12.6 0.1 0.43 10.5 0.1 2.2 1 0 0 1 1 1 0 Neuromedin U Peptidase_M22 PF00814.25 KFX93829.1 - 2.1e-75 253.9 0.0 2.4e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KFX93829.1 - 0.0035 17.1 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus AMPKBI PF04739.15 KFX93830.1 - 1.8e-25 89.0 1.5 1.8e-25 89.0 1.5 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KFX93830.1 - 1e-23 83.3 0.0 1.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pribosyl_synth PF14572.6 KFX93830.1 - 0.17 11.9 0.9 0.38 10.8 0.9 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Myc_target_1 PF15179.6 KFX93831.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 Pkinase PF00069.25 KFX93832.1 - 2.4e-60 204.2 0.0 3e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93832.1 - 3.5e-25 88.8 0.0 8.9e-24 84.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX93832.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX93832.1 - 0.017 14.5 0.1 0.097 12.0 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Peptidase_C78 PF07910.13 KFX93834.1 - 2.6e-68 229.7 0.0 4.5e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.16 KFX93834.1 - 8.6e-56 188.8 0.0 1.2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Ham1 family zf-Di19 PF05605.12 KFX93834.1 - 0.0089 16.3 0.2 0.28 11.5 0.0 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding dbPDZ_assoc PF16610.5 KFX93834.1 - 0.039 14.2 0.2 1.4 9.2 0.0 2.8 2 1 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 AAA_18 PF13238.6 KFX93835.1 - 8.2e-27 94.3 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX93835.1 - 2.8e-09 37.5 0.0 2.4e-08 34.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KFX93835.1 - 7.6e-06 26.4 0.1 0.0006 20.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KFX93835.1 - 0.00014 22.0 0.7 0.0051 16.9 0.7 2.4 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 KFX93835.1 - 0.00024 21.3 0.1 0.00049 20.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX93835.1 - 0.00035 20.9 0.0 0.00071 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFX93835.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 NTPase Hydin_ADK PF17213.3 KFX93835.1 - 0.00068 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 KFX93835.1 - 0.00092 19.5 0.4 0.002 18.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFX93835.1 - 0.0016 18.1 0.8 0.51 10.0 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.10 KFX93835.1 - 0.0023 17.4 0.0 0.0055 16.2 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFX93835.1 - 0.0092 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KFX93835.1 - 0.01 16.2 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFX93835.1 - 0.011 15.1 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 KFX93835.1 - 0.023 14.7 0.0 0.072 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX93835.1 - 0.031 14.0 0.5 0.073 12.8 0.2 1.8 1 1 0 2 2 2 0 AAA domain dNK PF01712.19 KFX93835.1 - 0.039 13.8 3.5 2 8.2 0.1 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase SKI PF01202.22 KFX93835.1 - 0.054 13.6 1.5 0.82 9.8 1.5 2.1 1 1 0 1 1 1 0 Shikimate kinase ATP_bind_1 PF03029.17 KFX93835.1 - 0.056 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 KFX93835.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFX93835.1 - 0.068 13.5 1.0 0.14 12.5 0.4 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFX93835.1 - 0.071 12.8 0.4 0.12 12.1 0.1 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein SRP54 PF00448.22 KFX93835.1 - 0.078 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX93835.1 - 0.091 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX93835.1 - 0.096 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 KFX93835.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family MeaB PF03308.16 KFX93835.1 - 0.11 11.4 0.9 0.15 11.1 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 KFX93835.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KFX93835.1 - 0.15 11.1 1.4 0.21 10.6 0.6 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KFX93835.1 - 0.17 11.6 2.0 2.2 8.0 0.6 2.3 1 1 1 2 2 2 0 AAA domain Myosin_head PF00063.21 KFX93836.1 - 8e-260 863.8 0.0 1.3e-259 863.1 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KFX93836.1 - 3.4e-26 91.5 2.9 3.4e-26 91.5 2.9 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KFX93836.1 - 2.2e-13 48.7 29.7 0.00027 20.5 1.3 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFX93836.1 - 0.00011 21.9 0.3 0.00031 20.5 0.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFX93836.1 - 0.00067 19.9 0.1 0.0035 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain KASH_CCD PF14662.6 KFX93836.1 - 0.0013 18.6 6.6 0.0013 18.6 6.6 2.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFX93836.1 - 0.0025 17.2 12.1 0.0025 17.2 12.1 2.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 KFX93836.1 - 0.0056 16.6 3.7 0.021 14.7 3.7 2.1 1 0 0 1 1 1 1 Sec34-like family AAA_16 PF13191.6 KFX93836.1 - 0.0067 16.8 0.0 0.044 14.2 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFX93836.1 - 0.16 12.4 0.1 0.81 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.12 KFX93836.1 - 0.37 10.8 4.4 2.8 8.0 4.4 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KFX93836.1 - 1 9.8 8.7 0.28 11.6 0.4 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.12 KFX93836.1 - 1.1 9.4 4.8 22 5.2 0.2 3.5 3 0 0 3 3 3 0 MbeD/MobD like DegQ PF08181.11 KFX93836.1 - 5.4 7.2 7.6 0.44 10.7 1.2 2.7 2 0 0 2 2 1 0 DegQ (SacQ) family ABC_tran PF00005.27 KFX93836.1 - 5.6 7.5 8.9 3.3 8.2 0.0 4.2 4 1 0 4 4 3 0 ABC transporter ArgJ PF01960.18 KFX93837.1 - 2.3e-150 500.5 0.6 2.7e-150 500.3 0.6 1.0 1 0 0 1 1 1 1 ArgJ family A_deamin PF02137.18 KFX93837.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain ORC2 PF04084.14 KFX93838.1 - 1.2e-123 412.2 0.0 1.5e-123 411.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 KFX93838.1 - 0.3 11.1 19.1 1.2 9.3 3.8 3.2 2 0 0 2 2 2 0 AT hook motif CDC27 PF09507.10 KFX93838.1 - 3.8 6.8 11.4 7.3 5.9 11.4 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-PARP PF00645.18 KFX93839.1 - 0.0049 17.7 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF410 PF04190.13 KFX93840.1 - 4e-93 311.9 0.0 4.7e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Response_reg PF00072.24 KFX93846.1 - 4.2e-20 72.0 0.0 2.7e-14 53.3 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain PQ-loop PF04193.14 KFX93847.1 - 2.2e-19 69.0 7.1 1.4e-11 43.9 0.3 3.1 2 1 1 3 3 3 2 PQ loop repeat Pep_deformylase PF01327.21 KFX93847.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Polypeptide deformylase ABC2_membrane_5 PF13346.6 KFX93847.1 - 0.24 10.9 15.1 0.081 12.5 9.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein SNase PF00565.17 KFX93848.1 - 5e-67 223.2 0.9 2.4e-23 82.6 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KFX93848.1 - 4.8e-23 81.5 0.0 1.3e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KFX93848.1 - 0.00015 21.1 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KFX93848.1 - 0.1 13.1 0.0 0.46 11.0 0.0 2.3 1 0 0 1 1 1 0 Agenet domain TPR_4 PF07721.14 KFX93848.1 - 1.2 10.0 3.6 3.4 8.6 1.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD PF00628.29 KFX93851.1 - 2.2e-09 37.0 2.0 2.2e-09 37.0 2.0 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KFX93851.1 - 0.0011 18.5 1.5 0.0018 17.8 1.5 1.4 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 KFX93851.1 - 0.0021 17.8 0.5 0.0061 16.4 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-CW PF07496.15 KFX93851.1 - 0.13 12.3 0.9 0.35 10.9 0.9 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger PHD PF00628.29 KFX93854.1 - 5.7e-07 29.3 8.9 1.1e-06 28.4 8.9 1.5 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.21 KFX93855.1 - 5.8e-32 110.9 7.0 5.8e-32 110.9 7.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 KFX93855.1 - 0.83 7.9 9.5 0.37 9.0 7.2 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 KFX93856.1 - 2.4e-10 40.8 5.9 0.00032 21.4 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFX93856.1 - 6.3e-05 22.1 0.0 0.39 9.6 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFX93856.1 - 0.013 15.8 0.0 4.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 KFX93858.1 - 3.6e-40 138.7 0.1 4.6e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX93858.1 - 3e-23 82.0 1.8 4.4e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain LRR_4 PF12799.7 KFX93859.1 - 3.4e-13 49.5 9.8 0.0038 17.6 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX93859.1 - 5.2e-11 42.2 24.5 1.8e-07 30.8 6.8 4.1 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 KFX93859.1 - 5.3e-05 23.2 9.0 29 5.7 0.3 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 KFX93859.1 - 0.00022 21.0 8.8 7.5 6.9 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFX93859.1 - 0.00058 19.4 2.2 0.004 16.7 0.2 2.4 2 1 1 3 3 3 2 Leucine-rich repeat Rdx PF10262.9 KFX93860.1 - 3.1e-32 110.6 0.0 5.4e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KFX93860.1 - 1.1e-22 79.8 0.0 1.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 GGL domain RPN7 PF10602.9 KFX93867.1 - 1.4e-43 148.6 0.7 2.9e-43 147.6 0.7 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFX93867.1 - 1.1e-13 51.6 0.7 6.2e-13 49.2 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KFX93867.1 - 0.011 15.8 5.1 1.4 9.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 KFX93867.1 - 0.082 11.6 2.0 3.9 6.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) TPR_1 PF00515.28 KFX93867.1 - 0.18 11.7 7.9 3.7 7.5 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3431 PF11913.8 KFX93868.1 - 2.2e-89 298.9 1.6 2.8e-89 298.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phasin PF05597.11 KFX93868.1 - 0.061 13.3 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phage_TAC_5 PF08890.11 KFX93868.1 - 0.16 11.9 1.6 2.3 8.2 0.1 2.4 1 1 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC HlyD_D23 PF16576.5 KFX93868.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Mhr1 PF12829.7 KFX93869.1 - 7.9e-34 115.6 0.1 1.4e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 KFX93870.1 - 2.3e-47 161.3 0.0 3.3e-46 157.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFX93870.1 - 1.8e-32 111.4 2.7 1.8e-32 111.4 2.7 3.7 3 1 0 4 4 3 1 AAA lid domain AAA PF00004.29 KFX93870.1 - 7.2e-26 91.2 0.1 6.3e-14 52.5 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFX93870.1 - 2.9e-25 88.1 0.2 1e-24 86.3 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFX93870.1 - 1.7e-14 54.0 0.0 5.8e-09 36.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX93870.1 - 3.9e-12 46.6 0.0 0.00016 21.9 0.0 4.3 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KFX93870.1 - 2.4e-11 44.3 9.5 5.1e-06 27.0 0.1 5.6 5 2 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KFX93870.1 - 6.4e-08 32.5 0.0 3.9e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFX93870.1 - 3.9e-06 26.4 0.0 0.24 10.8 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFX93870.1 - 5.9e-06 26.8 0.2 0.062 13.9 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KFX93870.1 - 7.5e-06 25.6 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFX93870.1 - 7.9e-06 25.7 0.0 0.082 12.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KFX93870.1 - 8.4e-06 26.0 0.0 0.27 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KFX93870.1 - 1.8e-05 24.8 0.0 0.22 11.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 KFX93870.1 - 1.9e-05 24.2 0.4 0.24 10.8 0.0 4.6 4 1 0 4 4 4 1 Bacterial TniB protein RNA_helicase PF00910.22 KFX93870.1 - 7.6e-05 23.1 0.0 0.53 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KFX93870.1 - 8.9e-05 22.8 0.1 0.52 10.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KFX93870.1 - 0.00014 21.6 0.0 0.18 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KFX93870.1 - 0.00026 20.9 0.0 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KFX93870.1 - 0.0003 20.9 3.2 0.024 14.8 0.1 3.9 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component RsgA_GTPase PF03193.16 KFX93870.1 - 0.00038 20.4 0.2 0.49 10.3 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase AAA_30 PF13604.6 KFX93870.1 - 0.00048 19.9 0.0 1.7 8.3 0.0 3.4 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.12 KFX93870.1 - 0.00055 19.7 0.2 8.5 6.1 0.0 4.6 5 0 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFX93870.1 - 0.00069 19.6 0.0 0.5 10.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFX93870.1 - 0.00087 19.6 0.3 0.31 11.4 0.0 3.8 5 0 0 5 5 3 1 AAA domain T2SSE PF00437.20 KFX93870.1 - 0.0015 17.7 1.0 0.04 13.0 0.1 3.0 2 1 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KFX93870.1 - 0.002 18.1 9.2 0.051 13.5 0.1 4.7 5 1 0 5 5 3 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KFX93870.1 - 0.0034 17.9 3.0 1 9.9 0.0 3.7 4 0 0 4 4 3 1 ABC transporter AAA_29 PF13555.6 KFX93870.1 - 0.0045 16.7 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KFX93870.1 - 0.0079 16.1 0.0 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 KFX93870.1 - 0.0099 15.2 0.0 0.97 8.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 KFX93870.1 - 0.01 16.0 0.0 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 KFX93870.1 - 0.011 15.8 0.0 2.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KFX93870.1 - 0.012 15.7 0.0 0.1 12.7 0.0 2.4 3 0 0 3 3 2 0 Torsin Rad17 PF03215.15 KFX93870.1 - 0.026 14.4 0.0 9.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KFX93870.1 - 0.031 13.8 1.4 3.2 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KFX93870.1 - 0.038 13.9 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 KFX93870.1 - 0.053 13.1 0.0 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KFX93870.1 - 0.081 13.4 0.0 0.081 13.4 0.0 4.8 4 2 1 5 5 3 0 AAA domain PduV-EutP PF10662.9 KFX93870.1 - 0.097 12.4 0.0 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFX93870.1 - 0.11 12.3 0.5 7.2 6.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system CbiA PF01656.23 KFX93870.1 - 0.21 11.7 0.5 49 4.0 0.0 3.6 5 0 0 5 5 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain V_ATPase_I PF01496.19 KFX93870.1 - 2.5 5.9 4.7 0.46 8.3 0.9 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KFX93870.1 - 4.4 6.6 14.8 0.2 11.0 8.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Methyltransf_25 PF13649.6 KFX93871.1 - 2.8e-11 44.0 0.0 8.7e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX93871.1 - 7e-11 42.6 0.0 1.9e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX93871.1 - 3.1e-08 34.3 0.0 6.4e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX93871.1 - 8e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX93871.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX93871.1 - 0.00031 20.6 0.0 0.00055 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KFX93871.1 - 0.21 10.6 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Biotin_lipoyl PF00364.22 KFX93872.1 - 5.9e-20 70.9 0.8 1.6e-19 69.5 0.8 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFX93872.1 - 1.3e-05 25.5 1.3 2.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFX93872.1 - 0.00051 19.8 0.3 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HTH_Tnp_ISL3 PF13542.6 KFX93872.1 - 0.11 11.9 1.4 0.2 11.1 0.8 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF3306 PF11748.8 KFX93872.1 - 3.2 8.7 10.5 3.2 8.6 3.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) CNH PF00780.22 KFX93896.1 - 1.2e-79 267.8 0.0 1.9e-79 267.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KFX93896.1 - 1.2e-44 151.6 0.0 3.2e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KFX93896.1 - 3.4e-36 125.2 0.0 5.6e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFX93896.1 - 5.7e-14 51.9 0.0 2e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KFX93896.1 - 0.0059 16.4 0.1 0.06 13.1 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFX93896.1 - 0.066 13.7 0.0 3.4 8.2 0.0 2.9 2 0 0 2 2 2 0 PH domain Mito_carr PF00153.27 KFX93898.1 - 4.6e-06 26.5 0.1 6.1e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Redoxin PF08534.10 KFX93906.1 - 7.5e-26 90.6 0.0 8.9e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFX93906.1 - 1.5e-05 24.9 0.0 1.9e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Rhodanese PF00581.20 KFX93908.1 - 1.3e-06 28.9 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HlyD_D4 PF16572.5 KFX93908.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF5616 PF18481.1 KFX93908.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) SBF PF01758.16 KFX93909.1 - 7.2e-50 169.4 14.5 7.2e-50 169.4 14.5 1.9 1 1 0 1 1 1 1 Sodium Bile acid symporter family DUF2897 PF11446.8 KFX93909.1 - 1.9 8.4 4.2 7 6.6 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) MFS_1 PF07690.16 KFX93910.1 - 3.6e-29 101.8 71.4 1.2e-26 93.5 46.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX93910.1 - 0.023 13.6 38.1 0.011 14.7 6.0 2.8 3 0 0 3 3 3 0 Sugar (and other) transporter FMN_dh PF01070.18 KFX93925.1 - 5.6e-117 390.6 0.0 6.5e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFX93925.1 - 1.6e-06 27.5 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFX93925.1 - 1.7e-05 24.0 0.7 0.00014 21.0 0.2 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KFX93925.1 - 8.8e-05 21.9 0.0 0.038 13.3 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KFX93925.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KFX93925.1 - 0.05 12.8 0.1 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KFX93925.1 - 0.1 12.1 0.1 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Dus PF01207.17 KFX93925.1 - 0.12 11.4 0.0 5.2 6.1 0.0 2.4 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) Methyltransf_16 PF10294.9 KFX93929.1 - 6.2e-41 140.0 0.0 9.9e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFX93929.1 - 4.8e-06 27.2 0.0 1.5e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFX93929.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFX93929.1 - 0.00018 21.1 0.0 0.00048 19.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFX93929.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX93929.1 - 0.0059 17.3 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX93929.1 - 0.0076 16.9 0.0 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 KFX93929.1 - 0.042 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.12 KFX93929.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FAA_hydrolase PF01557.18 KFX93930.1 - 6.3e-53 179.7 0.0 8.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFX93930.1 - 5.2e-33 113.4 0.0 1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.22 KFX93931.1 - 4.1e-58 197.2 0.0 5e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KFX93932.1 - 7.3e-15 54.7 0.0 1.8e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93932.1 - 7.7e-09 35.5 10.6 1.5e-08 34.6 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFX93934.1 - 1.9e-77 261.1 22.8 2.2e-77 260.8 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93934.1 - 1.3e-32 113.1 35.8 2e-27 96.1 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX93934.1 - 6.1e-06 24.9 8.0 9.3e-05 21.0 6.0 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) 7tm_6 PF02949.20 KFX93934.1 - 0.26 10.3 3.2 0.38 9.8 0.2 2.4 2 1 1 3 3 3 0 7tm Odorant receptor NPV_P10 PF05531.12 KFX93937.1 - 0.0088 16.5 0.2 18 5.9 0.0 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein OppC_N PF12911.7 KFX93937.1 - 0.048 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Baculo_PEP_C PF04513.12 KFX93937.1 - 0.14 12.2 0.7 3.4 7.7 0.0 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MitMem_reg PF13012.6 KFX93937.1 - 0.21 12.0 1.7 0.94 9.9 0.1 2.5 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function DUF4094 PF13334.6 KFX93937.1 - 0.25 11.8 6.4 0.43 11.0 2.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Uds1 PF15456.6 KFX93937.1 - 0.37 11.0 8.3 0.1 12.8 3.2 2.4 2 1 0 2 2 2 0 Up-regulated During Septation Allexi_40kDa PF05549.11 KFX93937.1 - 0.46 10.0 5.7 1.3 8.4 0.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 KFX93937.1 - 0.8 9.6 6.8 0.69 9.8 0.8 2.8 2 2 1 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4659 PF15558.6 KFX93937.1 - 3.1 6.6 15.7 0.13 11.1 10.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4659) DUF948 PF06103.11 KFX93937.1 - 6.6 7.1 8.4 10 6.4 0.2 3.7 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) adh_short_C2 PF13561.6 KFX93938.1 - 4.1e-53 180.3 1.2 5e-53 180.1 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX93938.1 - 1.1e-44 152.3 0.7 1.4e-44 151.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX93938.1 - 1.7e-07 31.3 0.1 5.4e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 KR domain RabGAP-TBC PF00566.18 KFX93939.1 - 2.3e-50 171.2 0.0 4.2e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBP_bac_11 PF13531.6 KFX93940.1 - 0.015 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein PAP2 PF01569.21 KFX93941.1 - 4e-16 59.0 2.4 1e-15 57.7 2.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFX93941.1 - 0.091 12.4 9.0 0.32 10.6 9.0 2.0 1 1 0 1 1 1 0 PAP2 superfamily HLH PF00010.26 KFX93943.1 - 4.4e-08 33.0 0.0 9.9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.19 KFX93949.1 - 0.00034 20.2 12.0 0.51 10.4 8.1 3.2 2 0 0 2 2 2 2 AT hook motif SRI PF08236.11 KFX93952.1 - 6.2e-21 74.4 11.8 1.8e-20 72.9 11.8 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KFX93952.1 - 2.7e-18 66.9 0.3 2.7e-18 66.9 0.3 3.5 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KFX93952.1 - 1.6e-13 50.4 13.3 1.6e-13 50.4 13.3 2.4 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KFX93952.1 - 0.00016 21.6 0.1 0.00059 19.8 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 KFX93952.1 - 0.0023 18.0 1.1 0.0063 16.6 1.1 1.8 1 0 0 1 1 1 1 WW domain CRAL_TRIO PF00650.20 KFX93955.1 - 5.8e-37 126.9 0.0 8.8e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX93955.1 - 1.5e-06 28.3 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFX93955.1 - 0.00047 20.3 0.0 0.0011 19.2 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Prefoldin PF02996.17 KFX93956.1 - 1.4e-31 108.9 0.2 2.9e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFX93956.1 - 0.0064 16.4 0.7 0.085 12.8 0.0 2.4 2 1 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 KFX93956.1 - 0.0097 16.4 0.6 4.5 7.9 0.0 2.2 2 0 0 2 2 2 2 Syntaxin 6, N-terminal THOC7 PF05615.13 KFX93956.1 - 0.032 14.5 0.4 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 End3 PF12761.7 KFX93956.1 - 0.066 13.4 0.3 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 KFX93956.1 - 0.067 13.8 1.0 5.6 7.7 0.2 2.7 3 0 0 3 3 3 0 SlyX DUF4795 PF16043.5 KFX93956.1 - 0.13 11.9 1.6 2.9 7.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3112 PF11309.8 KFX93957.1 - 4.5e-12 45.9 7.6 7.3e-06 25.6 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) NPCC PF08058.11 KFX93957.1 - 0.22 11.6 1.3 0.48 10.5 1.3 1.7 1 1 0 1 1 1 0 Nuclear pore complex component YwiC PF14256.6 KFX93957.1 - 1 9.7 11.2 6.8 7.0 4.0 2.6 2 1 0 2 2 2 0 YwiC-like protein Zn_clus PF00172.18 KFX93958.1 - 1.1e-06 28.6 9.6 2.1e-06 27.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 KFX93958.1 - 0.16 11.8 5.7 0.1 12.4 3.0 1.9 2 0 0 2 2 2 0 MCM OB domain Tom6 PF17112.5 KFX93965.1 - 0.083 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal SNF2_N PF00176.23 KFX93968.1 - 7.7e-72 241.9 0.3 7.7e-72 241.9 0.3 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX93968.1 - 1.3e-19 70.5 1.7 3.3e-18 66.0 0.0 3.9 4 1 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 KFX93968.1 - 1.6e-18 66.7 13.5 1.6e-18 66.7 13.5 4.2 4 0 0 4 4 4 1 HSA Bromodomain PF00439.25 KFX93968.1 - 2.3e-18 66.1 0.2 8.5e-18 64.2 0.2 2.0 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KFX93968.1 - 3.1e-13 50.1 1.0 3.1e-13 50.1 1.0 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KFX93968.1 - 8.7e-13 47.8 0.9 2.8e-12 46.2 0.9 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KFX93968.1 - 3e-11 43.6 2.9 4.1e-11 43.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MARVEL PF01284.23 KFX93968.1 - 1.5 8.8 10.8 2.9 7.9 10.8 1.4 1 0 0 1 1 1 0 Membrane-associating domain TPR_2 PF07719.17 KFX93969.1 - 2.3e-30 102.2 19.3 0.00015 21.6 0.1 11.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93969.1 - 2.7e-29 99.8 21.3 4.3e-06 26.3 0.1 10.9 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFX93969.1 - 2.4e-18 66.2 15.2 0.014 15.6 0.0 9.8 9 2 1 10 10 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFX93969.1 - 1.3e-16 59.3 21.2 0.0059 16.7 0.1 11.2 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX93969.1 - 7.8e-16 58.3 22.7 0.021 15.4 0.0 10.6 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX93969.1 - 2.7e-12 45.8 22.3 0.00055 19.8 0.1 11.3 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX93969.1 - 6.6e-12 45.2 35.8 0.022 15.5 0.0 12.1 11 2 2 13 13 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX93969.1 - 5.2e-11 42.1 3.2 8.1 7.1 0.0 9.7 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX93969.1 - 4.1e-07 30.5 4.4 2.4e-05 24.9 1.1 8.1 9 1 2 11 11 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX93969.1 - 4.9e-06 26.1 19.4 0.32 10.7 0.3 8.8 7 2 3 10 10 10 2 TPR repeat TPR_6 PF13174.6 KFX93969.1 - 9.6e-06 25.9 19.8 3.3 8.5 0.0 10.8 12 0 0 12 12 11 1 Tetratricopeptide repeat RPN7 PF10602.9 KFX93969.1 - 0.0024 17.6 1.2 0.0024 17.6 1.2 4.1 3 1 1 4 4 3 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 KFX93969.1 - 0.0039 17.0 25.3 0.97 9.4 0.0 8.4 10 0 0 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX93969.1 - 0.021 15.0 5.3 7.8 6.8 0.2 5.6 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFX93969.1 - 0.87 9.7 10.8 3.3 7.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KFX93969.1 - 7.8 6.7 6.7 26 5.0 0.1 4.4 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat SET PF00856.28 KFX93971.1 - 0.00022 21.7 0.0 0.00055 20.4 0.0 1.6 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 KFX93972.1 - 9.6e-09 35.0 0.3 3.9e-08 33.1 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX93972.1 - 0.0019 18.0 0.6 0.0068 16.3 0.3 2.3 1 1 0 1 1 1 1 F-box domain COesterase PF00135.28 KFX93973.1 - 2e-80 271.1 0.0 2.5e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX93973.1 - 5.3e-06 26.4 0.2 1.5e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX93973.1 - 0.13 11.1 0.2 0.32 9.8 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase Aconitase PF00330.20 KFX93974.1 - 7.9e-108 361.4 0.4 5.8e-107 358.5 0.4 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFX93974.1 - 3.4e-24 85.6 0.0 6.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MCM PF00493.23 KFX93974.1 - 0.086 11.9 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain Erf4 PF10256.9 KFX93976.1 - 8.4e-28 96.8 0.0 9.7e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family polyprenyl_synt PF00348.17 KFX93988.1 - 6.8e-54 182.6 0.0 8e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase 2OG-FeII_Oxy PF03171.20 KFX93999.1 - 2.9e-14 53.4 0.0 4.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-met2 PF12907.7 KFX94000.1 - 5.7e-15 55.2 4.3 8.2e-15 54.7 4.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KFX94000.1 - 0.00015 22.5 9.1 0.00024 21.9 9.1 1.3 1 0 0 1 1 1 1 4F5 protein family DNA_primase_lrg PF04104.14 KFX94004.1 - 9e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF2264 PF10022.9 KFX94005.1 - 2.2e-133 444.8 0.0 2.7e-133 444.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.24 KFX94006.1 - 5.6e-116 388.1 19.4 6.5e-116 387.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94006.1 - 8.7e-22 77.5 26.6 8.7e-22 77.5 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4457 PF14652.6 KFX94006.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Methyltransf_11 PF08241.12 KFX94007.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.23 KFX94016.1 - 6.1e-09 36.1 0.0 6.5e-08 32.8 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KFX94016.1 - 0.047 12.9 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase TFIIA_gamma_C PF02751.14 KFX94019.1 - 1.2e-10 41.3 0.3 2.3e-10 40.4 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KFX94019.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Ly-6_related PF06579.12 KFX94019.1 - 0.054 13.7 0.1 0.071 13.4 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Pro_isomerase PF00160.21 KFX94020.1 - 3.8e-41 141.0 0.0 8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ndc1_Nup PF09531.10 KFX94020.1 - 3.2 6.3 7.3 4.5 5.9 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.14 KFX94020.1 - 4.9 6.9 8.4 0.22 11.3 2.1 1.8 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF4291 PF14124.6 KFX94021.1 - 1.4e-67 227.1 0.4 1.8e-67 226.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) K_trans PF02705.16 KFX94022.1 - 1.2e-183 611.5 26.9 1.5e-183 611.2 26.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter zf-RING_2 PF13639.6 KFX94023.1 - 9.5e-14 51.5 6.2 1.5e-13 50.8 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX94023.1 - 2.6e-11 43.1 4.4 4.4e-11 42.3 4.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFX94023.1 - 3.4e-09 36.5 4.7 5.5e-09 35.8 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX94023.1 - 1e-08 34.9 5.3 1.7e-08 34.2 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX94023.1 - 2.8e-08 33.5 6.5 4.6e-08 32.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX94023.1 - 1.6e-07 31.5 7.1 6e-07 29.7 7.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFX94023.1 - 3.3e-07 30.0 4.8 6.1e-07 29.2 4.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX94023.1 - 3.5e-07 30.0 3.5 5.3e-07 29.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX94023.1 - 2.5e-06 27.4 3.6 2.6e-06 27.3 1.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFX94023.1 - 0.00013 22.0 1.2 0.00026 21.0 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFX94023.1 - 0.001 18.7 2.4 0.0017 17.9 2.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFX94023.1 - 0.0054 16.5 3.6 0.0089 15.8 3.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 KFX94023.1 - 0.0067 16.9 3.9 0.34 11.4 1.1 2.9 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.8 KFX94023.1 - 0.0072 16.5 6.1 0.17 12.1 6.1 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 KFX94023.1 - 0.013 15.6 3.0 0.034 14.3 3.0 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 KFX94023.1 - 0.014 15.4 2.6 0.044 13.8 2.6 1.8 1 1 0 1 1 1 0 Zinc-finger zf-P11 PF03854.14 KFX94023.1 - 0.031 13.9 4.1 0.059 13.0 4.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger PHD PF00628.29 KFX94023.1 - 0.033 14.1 3.0 0.062 13.2 3.0 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KFX94023.1 - 0.047 13.6 2.7 0.36 10.7 0.6 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFX94023.1 - 0.072 13.2 1.6 0.16 12.1 1.6 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger GAGA PF09237.11 KFX94023.1 - 0.072 12.9 1.6 0.58 10.0 0.2 2.4 2 0 0 2 2 2 0 GAGA factor U-box PF04564.15 KFX94023.1 - 0.089 13.0 0.0 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-C3HC4_4 PF15227.6 KFX94023.1 - 0.11 12.7 4.7 0.33 11.2 4.7 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 KFX94023.1 - 0.18 11.8 4.3 1.6 8.7 1.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cation_ATPase_C PF00689.21 KFX94024.1 - 1e-39 136.2 4.5 1e-39 136.2 4.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX94024.1 - 1.5e-37 128.9 2.0 1.5e-37 128.9 2.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFX94024.1 - 1.9e-24 87.1 0.0 2.7e-14 54.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX94024.1 - 5.4e-22 77.7 0.0 1.1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX94024.1 - 2.9e-09 36.5 0.0 6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 KFX94024.1 - 0.00059 20.3 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX94024.1 - 0.00078 19.3 0.4 0.0019 18.0 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFX94024.1 - 0.0081 15.1 5.1 0.32 9.8 4.1 2.5 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG DUF2207 PF09972.9 KFX94024.1 - 0.24 10.1 0.0 0.24 10.1 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Nucleos_tra2_N PF01773.20 KFX94024.1 - 9.1 7.0 8.2 8.1 7.1 0.1 3.5 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus DUF21 PF01595.20 KFX94025.1 - 1.6e-30 106.1 0.7 7.2e-30 104.0 0.2 1.9 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFX94025.1 - 6.6e-08 32.9 0.2 1.9e-05 25.0 0.1 3.0 3 0 0 3 3 3 1 CBS domain BtrH_N PF14399.6 KFX94025.1 - 0.091 13.0 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SieB PF14163.6 KFX94025.1 - 0.16 11.5 0.7 5.5 6.5 0.4 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B DS PF01916.17 KFX94026.1 - 3.6e-132 439.9 0.1 4.2e-132 439.7 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase B5 PF03484.15 KFX94026.1 - 0.16 12.3 0.5 2.1 8.7 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetase B5 domain Myb_DNA-binding PF00249.31 KFX94027.1 - 3e-09 36.9 0.1 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX94027.1 - 0.05 13.9 4.2 5.1 7.4 0.5 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFX94027.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like P21-Arc PF04062.14 KFX94028.1 - 4.7e-73 244.9 0.0 5.4e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 KFX94029.1 - 1.5e-120 401.8 0.0 1.9e-120 401.5 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family VEFS-Box PF09733.9 KFX94030.1 - 0.00042 20.1 2.6 0.00042 20.1 2.6 2.6 3 0 0 3 3 3 1 VEFS-Box of polycomb protein zf-RING_11 PF17123.5 KFX94030.1 - 0.028 14.2 2.0 6.5 6.6 0.4 2.7 2 0 0 2 2 2 0 RING-like zinc finger Vps5 PF09325.10 KFX94030.1 - 0.22 11.1 1.3 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Vps5 C terminal like WD40 PF00400.32 KFX94045.1 - 1.1e-07 32.3 7.4 0.38 11.7 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94045.1 - 0.0089 16.3 0.1 0.084 13.2 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KFX94046.1 - 2.6e-12 46.3 1.2 2e-11 43.4 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain GST_N_2 PF13409.6 KFX94047.1 - 1.7e-20 73.1 0.0 5.5e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX94047.1 - 9e-13 48.1 0.0 2.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX94047.1 - 3e-06 27.5 0.1 9.9e-05 22.7 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX94047.1 - 0.029 14.6 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pacs-1 PF10254.9 KFX94047.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein MFS_1 PF07690.16 KFX94048.1 - 1.5e-26 93.1 29.0 1.5e-26 93.1 29.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_tran PF00005.27 KFX94049.1 - 4.6e-28 98.4 0.0 1.2e-14 55.0 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFX94049.1 - 3.9e-12 46.6 1.6 0.0063 16.4 0.0 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX94049.1 - 7.7e-07 29.8 1.5 0.051 14.1 1.6 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX94049.1 - 0.00016 21.3 0.0 0.075 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KFX94049.1 - 0.00021 21.5 0.0 0.0045 17.2 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 KFX94049.1 - 0.0023 18.2 0.0 3.9 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFX94049.1 - 0.0089 15.8 1.1 0.7 9.5 1.8 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KFX94049.1 - 0.013 15.5 0.0 4 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 KFX94049.1 - 0.019 15.5 0.0 3.6 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX94049.1 - 0.023 14.5 0.1 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX94049.1 - 0.023 13.9 0.0 1.1 8.4 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFX94049.1 - 0.037 13.4 0.0 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KFX94049.1 - 0.05 13.7 0.0 18 5.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KFX94049.1 - 0.064 12.7 0.0 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 KFX94049.1 - 0.075 13.4 0.0 14 6.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFX94049.1 - 0.087 12.7 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KFX94049.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase1 PF18748.1 KFX94049.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_33 PF13671.6 KFX94049.1 - 0.13 12.5 0.0 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KFX94049.1 - 0.13 11.8 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFX94049.1 - 0.17 11.7 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Pantoate_ligase PF02569.15 KFX94053.1 - 3.6e-93 311.6 0.0 4.2e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Methyltransf_2 PF00891.18 KFX94059.1 - 9.1e-16 57.8 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KFX94059.1 - 0.0003 20.7 0.3 0.0011 18.9 0.3 2.0 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KFX94059.1 - 0.00061 19.7 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 Dimerisation domain HTH_24 PF13412.6 KFX94059.1 - 0.0019 17.7 0.0 0.0083 15.7 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KFX94059.1 - 0.0021 17.9 0.0 0.0057 16.5 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KFX94059.1 - 0.063 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF3164 PF11363.8 KFX94059.1 - 0.2 11.3 0.1 0.9 9.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3164) HTH_IclR PF09339.10 KFX94059.1 - 0.23 11.3 0.8 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain APH PF01636.23 KFX94060.1 - 1.5e-05 25.0 0.1 2.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX94060.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FA_desaturase PF00487.24 KFX94083.1 - 2e-22 80.3 23.2 5.8e-22 78.8 23.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFX94083.1 - 2.2e-05 24.7 0.0 4.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SMC_N PF02463.19 KFX94084.1 - 2.2e-67 226.7 0.0 3.1e-66 223.0 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX94084.1 - 5.7e-27 94.4 0.1 2.2e-26 92.4 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFX94084.1 - 7.1e-18 65.8 7.3 7.1e-18 65.8 7.3 6.0 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 KFX94084.1 - 1.4e-14 54.7 7.1 8.7e-07 29.0 1.8 3.5 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX94084.1 - 1.6e-13 51.2 36.3 1.1e-09 38.5 15.6 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFX94084.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KFX94084.1 - 0.44 11.1 0.0 0.44 11.1 0.0 5.7 3 2 0 3 3 3 0 ABC transporter APG6_N PF17675.1 KFX94084.1 - 9.5 6.8 120.3 0.079 13.5 12.7 8.3 3 2 5 8 8 8 0 Apg6 coiled-coil region RIO1 PF01163.22 KFX94085.1 - 6e-67 224.9 0.0 6e-67 224.9 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFX94085.1 - 0.0039 16.6 0.3 0.035 13.5 0.3 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX94085.1 - 0.0082 16.1 0.6 1.2 9.0 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Prismane PF03063.20 KFX94085.1 - 0.053 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family PGA2 PF07543.12 KFX94085.1 - 6.1 6.8 15.2 5.9 6.9 9.6 2.7 2 0 0 2 2 2 0 Protein trafficking PGA2 SNARE PF05739.19 KFX94086.1 - 2.2e-14 53.2 0.9 4e-14 52.3 0.9 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFX94086.1 - 4.1e-05 23.3 7.0 0.0009 19.0 7.0 2.2 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KFX94086.1 - 0.0031 17.3 4.1 0.011 15.6 0.3 2.5 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KFX94086.1 - 0.033 14.5 1.5 0.033 14.5 1.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DNA_repr_REX1B PF14966.6 KFX94086.1 - 0.25 12.0 0.1 0.25 12.0 0.1 2.5 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.32 KFX94087.1 - 8.3e-41 134.5 12.9 1.3e-09 36.9 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFX94087.1 - 2.2e-35 120.9 5.7 1.4e-18 67.1 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFX94087.1 - 6.1e-34 115.7 11.6 2.9e-15 55.9 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFX94087.1 - 5.4e-30 100.7 8.0 3.2e-09 36.0 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX94087.1 - 4.6e-25 86.0 10.6 4.3e-06 26.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFX94087.1 - 3.4e-16 59.3 0.3 4.7e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFX94087.1 - 3.8e-09 36.9 0.6 0.0028 18.0 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFX94087.1 - 4.7e-08 32.9 2.7 0.0041 17.0 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KFX94087.1 - 3e-06 27.2 0.0 0.014 15.4 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFX94087.1 - 5.9e-05 23.1 1.5 0.00018 21.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KFX94087.1 - 7.8e-05 23.5 0.2 0.0015 19.4 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KFX94087.1 - 0.00026 21.0 0.4 0.62 10.0 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFX94087.1 - 0.0013 19.0 0.5 1.2 9.4 0.1 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 KFX94087.1 - 0.0035 17.3 3.2 0.77 9.7 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 KFX94087.1 - 0.012 15.8 6.3 0.58 10.4 0.4 3.0 1 1 2 3 3 3 0 Dockerin type I domain DUF5580 PF17743.1 KFX94087.1 - 0.019 13.5 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KFX94087.1 - 0.026 14.8 0.3 10 6.5 0.1 2.6 1 1 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 KFX94087.1 - 0.038 13.8 2.0 0.97 9.3 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF4497 PF14924.6 KFX94087.1 - 0.044 14.3 0.0 9.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Poly_export PF02563.16 KFX94087.1 - 0.05 13.8 0.0 0.33 11.2 0.0 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RloB PF13707.6 KFX94087.1 - 0.061 13.5 2.5 1.6 8.9 2.4 2.1 1 1 0 1 1 1 0 RloB-like protein MotA_activ PF09114.10 KFX94087.1 - 0.15 12.2 0.2 2.5 8.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Glyco_hydro_47 PF01532.20 KFX94088.1 - 6.1e-177 589.1 0.0 7.4e-177 588.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFX94088.1 - 0.11 11.6 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KFX94092.1 - 1.7e-92 310.7 27.2 1.9e-92 310.5 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94092.1 - 1.1e-26 93.6 42.9 4.3e-26 91.7 24.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX94092.1 - 2.1e-06 26.5 2.7 4e-06 25.6 2.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3021 PF11457.8 KFX94092.1 - 0.0081 16.5 5.5 0.0081 16.5 5.5 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3021) UPF0060 PF02694.15 KFX94092.1 - 0.026 14.8 0.4 0.026 14.8 0.4 2.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2530 PF10745.9 KFX94092.1 - 0.088 13.1 9.0 7.1 6.9 3.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF3180 PF11377.8 KFX94092.1 - 4.4 7.5 10.7 0.26 11.4 2.4 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3180) Glyco_hydro_3 PF00933.21 KFX94093.1 - 2e-60 204.9 0.0 2.6e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KFX94093.1 - 2.7e-50 171.2 0.0 4.4e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFX94093.1 - 2.9e-22 78.5 0.9 2.9e-22 78.5 0.9 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KFX94093.1 - 0.023 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF11 PF01345.18 KFX94093.1 - 0.076 13.3 0.4 0.2 12.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 GMC_oxred_N PF00732.19 KFX94094.1 - 2.3e-48 165.1 0.0 4.3e-48 164.2 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX94094.1 - 5.5e-37 127.5 0.1 9.6e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFX94094.1 - 7e-05 22.2 0.1 0.0003 20.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX94094.1 - 0.00019 20.7 0.7 0.0018 17.5 0.2 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KFX94094.1 - 0.0003 20.5 1.9 0.0038 16.9 1.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX94094.1 - 0.00036 19.7 1.4 0.014 14.5 1.4 2.4 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX94094.1 - 0.00053 19.3 0.6 0.27 10.4 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94094.1 - 0.00062 19.9 0.8 0.0019 18.4 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX94094.1 - 0.0015 17.7 1.6 0.0016 17.5 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KFX94094.1 - 0.082 11.6 0.2 0.2 10.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KFX94094.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KFX94094.1 - 0.14 12.1 0.3 0.36 10.8 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ank_2 PF12796.7 KFX94095.1 - 9.8e-23 80.6 0.6 1.2e-07 32.2 0.6 5.0 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX94095.1 - 3.9e-17 62.1 0.5 6.8e-07 29.4 0.0 5.1 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX94095.1 - 9.7e-17 61.1 3.2 0.00022 21.7 0.2 7.7 6 1 2 8 8 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94095.1 - 3.2e-14 51.6 2.1 0.059 13.9 0.0 8.7 10 0 0 10 10 9 3 Ankyrin repeat Ank PF00023.30 KFX94095.1 - 2.2e-10 40.5 6.2 0.0041 17.5 0.1 6.5 7 0 0 7 7 6 2 Ankyrin repeat Zeta_toxin PF06414.12 KFX94095.1 - 2.3e-05 23.8 0.2 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KFX94095.1 - 0.00018 21.9 0.0 0.00056 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 KFX94095.1 - 0.00082 19.2 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 KFX94095.1 - 0.0019 18.5 0.0 0.0075 16.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX94095.1 - 0.0025 17.8 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KFX94095.1 - 0.012 16.0 0.5 0.52 10.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LCAT PF02450.15 KFX94095.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 KFX94095.1 - 0.035 13.4 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX94095.1 - 0.044 14.4 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_25 PF13481.6 KFX94095.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFX94095.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFX94095.1 - 0.18 12.1 0.0 0.47 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 KFX94096.1 - 9.1e-61 206.0 0.0 1.1e-60 205.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 KFX94097.1 - 7.8e-20 71.1 34.9 1.4e-19 70.2 34.9 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Proton_antipo_C PF01010.19 KFX94097.1 - 0.01 15.5 0.1 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Glyco_hydro_28 PF00295.17 KFX94099.1 - 9.7e-46 156.3 10.2 1.2e-45 156.0 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFX94099.1 - 3.4e-05 23.8 11.3 0.00045 20.1 6.9 2.6 2 1 1 3 3 3 2 Right handed beta helix region End_N_terminal PF12218.8 KFX94099.1 - 0.013 15.2 0.4 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Seadorna_VP6 PF07407.11 KFX94099.1 - 0.25 10.3 0.9 0.34 9.8 0.9 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Pectinesterase PF01095.19 KFX94100.1 - 2.2e-46 158.0 6.6 2.9e-46 157.6 6.6 1.1 1 0 0 1 1 1 1 Pectinesterase HSP70 PF00012.20 KFX94101.1 - 0.015 13.5 0.0 0.026 12.7 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein YjeF_N PF03853.15 KFX94103.1 - 3e-38 131.4 0.0 4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KFX94103.1 - 2.3e-06 28.4 0.1 4.8e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 FDF domain RAI1 PF08652.11 KFX94110.1 - 6.7e-27 93.5 0.0 1.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease FA_hydroxylase PF04116.13 KFX94111.1 - 2.9e-23 82.7 15.4 2.9e-23 82.7 15.4 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily NLE PF08154.12 KFX94112.1 - 1.9e-17 63.6 0.5 2.8e-17 63.0 0.5 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KFX94112.1 - 0.21 12.5 1.1 0.44 11.5 0.2 2.0 1 1 0 2 2 2 0 WD domain, G-beta repeat Aa_trans PF01490.18 KFX94113.1 - 6.7e-83 278.7 33.0 8.1e-83 278.4 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 KFX94113.1 - 0.73 10.3 6.6 0.72 10.3 0.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) AA_permease PF00324.21 KFX94114.1 - 6.6e-57 193.2 35.4 8.5e-57 192.8 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFX94114.1 - 1.9e-19 70.1 8.7 2.8e-08 33.2 0.0 4.4 5 0 0 5 5 5 3 Solute carrier family 12 DUF899 PF05988.12 KFX94115.1 - 1e-43 149.4 0.0 1.3e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DNA_pol_E_B PF04042.16 KFX94116.1 - 1.6e-46 158.4 0.0 2e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KFX94116.1 - 6.5e-40 136.2 0.0 1e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF3445 PF11927.8 KFX94118.1 - 1.2e-69 234.4 0.0 1.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Acetyltransf_3 PF13302.7 KFX94119.1 - 1.9e-17 64.2 0.0 4.8e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX94119.1 - 0.0034 17.3 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 KFX94119.1 - 0.008 15.9 0.3 3.1 7.5 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX94119.1 - 0.045 13.7 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX94119.1 - 0.087 13.1 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pec_lyase_C PF00544.19 KFX94120.1 - 5.2e-15 55.6 13.3 2.3e-14 53.5 9.9 2.6 2 1 0 2 2 2 1 Pectate lyase Fe-ADH PF00465.19 KFX94126.1 - 6.9e-64 215.9 0.0 9.8e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Zds_C PF08632.10 KFX94126.1 - 1e-28 98.8 1.0 2e-28 97.9 1.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Fe-ADH_2 PF13685.6 KFX94126.1 - 3.2e-11 43.4 0.0 7.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase adh_short PF00106.25 KFX94127.1 - 2.1e-28 99.1 0.0 1.7e-27 96.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94127.1 - 6.1e-16 58.7 0.0 2.1e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX94127.1 - 3.5e-08 33.6 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX94127.1 - 1.5e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX94127.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFX94127.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dfp1_Him1_M PF08630.10 KFX94128.1 - 7.9e-46 155.4 0.0 1.8e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KFX94128.1 - 1.2e-20 73.3 0.6 1.2e-20 73.3 0.6 1.7 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.7 KFX94128.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Peptidase_M24 PF00557.24 KFX94129.1 - 2e-50 171.4 0.0 2.8e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFX94129.1 - 8.9e-39 132.0 0.0 1.5e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 KFX94129.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain APG12 PF04110.13 KFX94130.1 - 1.4e-29 102.3 0.0 1.9e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KFX94130.1 - 0.0015 18.7 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like MitMem_reg PF13012.6 KFX94130.1 - 0.084 13.3 0.0 0.12 12.8 0.0 1.3 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Pantoate_transf PF02548.15 KFX94131.1 - 3.1e-108 361.1 0.3 3.7e-108 360.8 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KFX94131.1 - 3e-06 26.9 0.1 5.5e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KFX94131.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) NanE PF04131.14 KFX94131.1 - 0.24 10.6 2.3 10 5.2 0.0 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase UQ_con PF00179.26 KFX94132.1 - 6.1e-19 68.1 0.0 7.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SelK_SelG PF10961.8 KFX94133.1 - 0.11 13.1 0.3 0.61 10.7 0.3 2.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG HMG_CoA_synt_C PF08540.10 KFX94134.1 - 2.9e-103 345.3 0.0 4.1e-103 344.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFX94134.1 - 3.8e-94 313.4 0.4 5.6e-94 312.9 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal SAP PF02037.27 KFX94135.1 - 8.2e-14 51.0 0.0 1.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KFX94135.1 - 0.0011 18.7 0.3 0.0035 17.0 0.3 1.8 1 1 0 1 1 1 1 HeH/LEM domain Cadherin_4 PF17803.1 KFX94135.1 - 4.2 8.1 10.2 6.4 7.5 0.4 2.6 2 1 0 2 2 2 0 Bacterial cadherin-like domain Dicty_CAR PF05462.11 KFX94136.1 - 3.1e-17 62.7 8.4 4.9e-17 62.0 8.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFX94136.1 - 2.9e-09 36.6 0.2 4.5e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KFX94136.1 - 3.5e-09 36.3 9.3 5.7e-09 35.6 9.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KFX94136.1 - 6.9e-06 26.0 11.3 1.2e-05 25.2 11.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 KFX94136.1 - 0.0058 15.7 11.3 2.6 7.0 11.3 2.2 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region TRAM_LAG1_CLN8 PF03798.16 KFX94141.1 - 3.6e-37 128.0 14.6 3.6e-37 128.0 14.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFX94141.1 - 8.2e-22 76.6 0.1 8.2e-22 76.6 0.1 1.7 2 0 0 2 2 2 1 TRAM1-like protein GDC-P PF02347.16 KFX94146.1 - 1.2e-179 597.7 0.0 1.3e-169 564.6 0.0 2.7 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFX94146.1 - 6.7e-06 25.6 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFX94146.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_5 PF13857.6 KFX94147.1 - 1.5e-12 47.5 0.9 1.3e-07 31.7 0.1 3.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94147.1 - 1.5e-12 46.5 0.5 0.024 15.2 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 KFX94147.1 - 3.3e-11 43.6 0.0 0.0013 19.3 0.0 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFX94147.1 - 1.6e-07 31.4 1.7 0.012 16.1 0.1 5.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFX94147.1 - 3.3e-07 30.7 3.9 0.41 11.3 0.0 6.3 3 2 4 7 7 7 2 Ankyrin repeats (many copies) Acetyltransf_10 PF13673.7 KFX94148.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX94148.1 - 2e-07 31.3 0.0 4.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX94148.1 - 6.5e-06 26.5 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2508 PF10704.9 KFX94148.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) ALAD PF00490.21 KFX94150.1 - 5.2e-102 341.3 0.0 5.8e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MFS_1 PF07690.16 KFX94165.1 - 2.6e-11 43.1 8.6 2.6e-11 43.1 8.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily MccV PF17508.2 KFX94165.1 - 1.3 9.6 4.5 9.3 6.9 0.1 3.1 3 0 0 3 3 3 0 Microcin V bacteriocin Glycos_transf_1 PF00534.20 KFX94166.1 - 2.5e-35 121.6 0.0 8.4e-35 119.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFX94166.1 - 4.5e-16 59.3 0.0 7.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFX94166.1 - 1.6e-14 54.4 0.2 5.1e-14 52.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFX94166.1 - 1.3e-07 32.2 1.7 1.5e-07 32.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFX94166.1 - 1.9e-05 25.0 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KFX94166.1 - 0.0018 18.4 1.4 0.27 11.3 0.0 2.4 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Terminase_6 PF03237.15 KFX94166.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family zf-C2H2 PF00096.26 KFX94174.1 - 3.5e-07 30.3 20.0 1e-05 25.7 3.8 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX94174.1 - 8.2e-06 26.0 6.9 2.2e-05 24.7 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX94174.1 - 2.3e-05 24.9 2.3 2.3e-05 24.9 2.3 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX94174.1 - 0.00039 20.3 1.8 0.00096 19.1 1.8 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX94174.1 - 0.00082 19.6 1.0 0.00082 19.6 1.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KFX94174.1 - 0.064 14.0 1.9 0.064 14.0 1.9 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 KFX94174.1 - 0.16 12.3 3.1 0.36 11.2 3.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFX94174.1 - 0.17 12.6 10.6 0.59 10.8 2.2 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 KFX94174.1 - 1.2 9.6 5.3 0.19 12.2 0.7 2.2 3 0 0 3 3 1 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KFX94174.1 - 1.6 9.3 4.9 3.5 8.1 4.9 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 KFX94174.1 - 6.4 6.6 9.5 0.57 10.0 2.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Ank_2 PF12796.7 KFX94175.1 - 1e-30 106.2 0.0 6e-12 46.0 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94175.1 - 8.4e-28 96.4 1.3 6.4e-05 23.4 0.0 7.2 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX94175.1 - 8.1e-24 83.4 2.5 5.7e-10 39.3 0.8 5.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX94175.1 - 1.9e-22 78.6 13.7 7.4e-06 26.2 0.1 8.6 9 0 0 9 9 8 4 Ankyrin repeat Ank_3 PF13606.6 KFX94175.1 - 4.7e-22 75.7 2.3 0.012 16.1 0.0 8.9 9 0 0 9 9 8 4 Ankyrin repeat AAA_16 PF13191.6 KFX94175.1 - 4.3e-07 30.5 0.0 1.3e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFX94175.1 - 5.4e-06 26.4 0.0 1.2e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KFX94175.1 - 8.2e-05 22.6 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KFX94175.1 - 0.0045 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFX94175.1 - 0.022 14.7 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KFX94175.1 - 0.028 14.3 0.0 0.077 12.9 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase MeaB PF03308.16 KFX94175.1 - 0.037 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KFX94175.1 - 0.042 13.8 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 KFX94175.1 - 0.046 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFX94175.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_3 PF14606.6 KFX94175.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AAA_19 PF13245.6 KFX94175.1 - 0.17 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFX94175.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KFX94175.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KFX94175.1 - 0.19 11.3 0.0 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UFD1 PF03152.14 KFX94176.1 - 3.2e-29 101.6 0.0 6.2e-23 81.1 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KFX94176.1 - 4.7e-05 23.5 0.8 0.00025 21.2 0.1 2.7 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Methyltransf_22 PF13383.6 KFX94177.1 - 1.7e-10 40.9 0.1 6.7e-07 29.1 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 KFX94177.1 - 1.8e-06 28.1 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain BTRD1 PF17660.1 KFX94177.1 - 0.056 13.3 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 GCIP PF13324.6 KFX94178.1 - 9e-21 74.7 0.3 2.2e-20 73.4 0.3 1.5 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 KFX94178.1 - 3.4 8.1 9.5 7.5 7.0 9.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Actin PF00022.19 KFX94179.1 - 3.2e-99 332.3 0.0 3e-98 329.1 0.0 1.9 1 1 0 1 1 1 1 Actin BPL_N PF09825.9 KFX94180.1 - 1.3e-144 481.9 0.0 1.8e-144 481.5 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KFX94180.1 - 2.9e-25 88.7 0.1 4.8e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KFX94180.1 - 0.0046 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF2250 PF10007.9 KFX94180.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) CHCH PF06747.13 KFX94181.1 - 4.8e-05 23.4 9.3 7.9e-05 22.7 9.3 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KFX94181.1 - 0.024 15.0 2.5 0.037 14.4 2.5 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KFX94181.1 - 0.08 13.0 8.5 3.3 7.8 8.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KFX94181.1 - 0.3 11.1 5.8 0.55 10.3 1.5 2.1 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Mgm101p PF06420.12 KFX94182.1 - 4.9e-88 293.1 0.0 6.7e-88 292.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Rtf2 PF04641.12 KFX94184.1 - 8.2e-55 186.0 1.6 9.6e-55 185.8 1.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KFX94184.1 - 7.1e-05 22.5 0.0 0.0036 17.1 0.0 2.6 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit Relaxase PF03432.14 KFX94184.1 - 0.041 13.5 0.4 0.071 12.7 0.4 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain zf-RING_5 PF14634.6 KFX94184.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FAT PF02259.23 KFX94185.1 - 2.6e-131 438.0 1.3 2.6e-131 438.0 1.3 2.1 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KFX94185.1 - 3.5e-77 257.8 7.4 2e-68 229.4 1.8 5.2 4 1 1 5 5 5 3 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KFX94185.1 - 6.4e-71 239.1 0.1 1.1e-70 238.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KFX94185.1 - 3.6e-44 149.2 1.9 1.1e-43 147.6 0.1 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KFX94185.1 - 2.9e-19 67.5 11.0 3.2e-05 23.8 0.0 11.7 12 0 0 12 12 11 2 HEAT repeat HEAT_2 PF13646.6 KFX94185.1 - 1.7e-15 57.1 16.9 0.0009 19.6 0.1 8.9 9 1 0 9 9 7 3 HEAT repeats HEAT_EZ PF13513.6 KFX94185.1 - 1.8e-11 44.3 16.2 0.00023 21.6 0.0 9.8 9 3 3 12 12 9 3 HEAT-like repeat FATC PF02260.20 KFX94185.1 - 2.7e-11 43.1 0.2 8.3e-11 41.5 0.2 1.9 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 KFX94185.1 - 1e-07 32.1 1.5 0.0043 17.1 0.0 5.9 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFX94185.1 - 1.4e-07 32.0 1.8 22 5.7 0.0 7.5 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFX94185.1 - 4.1e-06 25.7 9.6 0.0015 17.1 1.0 4.9 3 1 1 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 KFX94185.1 - 1.4e-05 24.7 2.4 0.22 11.1 0.0 5.4 5 1 0 5 5 5 1 CLASP N terminal IFRD PF05004.13 KFX94185.1 - 0.00014 21.1 0.0 0.64 9.1 0.0 4.0 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KFX94185.1 - 0.001 18.2 2.8 0.066 12.3 0.1 3.6 2 2 0 2 2 2 1 RNAPII transcription regulator C-terminal TPR_19 PF14559.6 KFX94185.1 - 0.015 15.8 3.2 43 4.7 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX94185.1 - 0.017 15.3 5.2 13 6.1 1.0 4.7 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DRIM PF07539.12 KFX94185.1 - 0.02 13.2 0.9 1.4 7.1 0.1 3.1 2 1 0 3 3 3 0 Down-regulated in metastasis DUF3730 PF12530.8 KFX94185.1 - 0.021 14.4 0.0 1.2 8.7 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) VirDNA-topo-I_N PF09266.10 KFX94185.1 - 0.1 12.8 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal TPR_7 PF13176.6 KFX94185.1 - 0.13 12.3 3.8 8.6 6.7 0.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Tti2 PF10521.9 KFX94185.1 - 0.15 11.6 3.2 3.2 7.2 0.8 3.4 3 0 0 3 3 3 0 Tti2 family Sec7_N PF12783.7 KFX94185.1 - 0.42 10.5 11.0 1.6 8.6 0.0 5.2 6 1 0 6 6 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_14 PF13428.6 KFX94185.1 - 1.3 10.0 5.9 10 7.2 0.3 4.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KFX94186.1 - 2.1e-61 207.7 0.0 2.6e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex24p PF06398.11 KFX94188.1 - 1.7e-95 320.1 0.3 2e-95 319.9 0.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Syntaxin-18_N PF10496.9 KFX94188.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PAP_assoc PF03828.19 KFX94189.1 - 4.2e-11 42.9 0.0 1.3e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFX94189.1 - 3.7e-07 30.4 0.0 8.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Thioredoxin PF00085.20 KFX94197.1 - 3.1e-33 113.8 0.1 1.1e-26 92.9 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 KFX94197.1 - 8.8e-07 28.6 0.6 4.4e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFX94197.1 - 1.2e-06 28.9 0.8 0.022 15.2 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 KFX94197.1 - 3.6e-06 27.0 1.1 0.00045 20.2 0.0 2.6 3 0 0 3 3 2 1 Thioredoxin-like domain TraF PF13728.6 KFX94197.1 - 1.3e-05 25.2 9.8 0.0017 18.2 0.0 3.4 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KFX94197.1 - 0.0021 18.3 0.0 0.22 11.9 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KFX94197.1 - 0.034 14.1 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KFX94197.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like X PF00739.19 KFX94197.1 - 0.14 12.2 0.1 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 Trans-activation protein X QSOX_Trx1 PF18108.1 KFX94197.1 - 0.17 12.1 0.0 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 QSOX Trx-like domain TRAP_alpha PF03896.16 KFX94197.1 - 0.27 10.4 3.9 0.48 9.6 2.1 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit U1snRNP70_N PF12220.8 KFX94197.1 - 0.41 11.3 8.1 0.082 13.6 3.0 2.4 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal NPR3 PF03666.13 KFX94197.1 - 0.96 8.2 4.5 1.4 7.6 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 KFX94197.1 - 1.7 7.5 12.0 2.7 6.8 12.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KFX94197.1 - 3.8 6.2 6.7 5.9 5.6 6.7 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KFX94197.1 - 5.5 7.4 8.8 14 6.1 8.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Vta1 PF04652.16 KFX94198.1 - 5e-55 185.5 3.5 5e-55 185.5 3.5 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFX94198.1 - 1.5e-15 56.6 0.1 3.7e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Vta1 C-terminal domain N-Term_TEN PF11474.8 KFX94198.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain TFR_dimer PF04253.15 KFX94199.1 - 3.3e-26 91.7 0.0 5.6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFX94199.1 - 2.6e-21 76.2 0.0 4.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX94199.1 - 1.3e-07 31.5 0.1 6.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KFX94199.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 KFX94200.1 - 6.4e-36 124.0 34.1 7.1e-28 97.5 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX94200.1 - 1.3e-09 37.5 6.2 1.3e-09 37.5 6.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFX94200.1 - 0.01 14.3 0.7 0.01 14.3 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aconitase_C PF00694.19 KFX94214.1 - 5.4e-27 94.7 0.0 1.5e-26 93.3 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain YCII PF03795.14 KFX94215.1 - 0.00053 20.3 0.0 0.00078 19.8 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Cut8 PF08559.10 KFX94216.1 - 3.6e-83 278.9 0.0 4.7e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF4953 PF16313.5 KFX94216.1 - 0.0039 16.4 0.1 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Met-zincin DUF2408 PF10303.9 KFX94217.1 - 5.1e-42 143.6 1.0 2.1e-24 86.6 0.1 4.9 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) PolyG_pol PF01518.16 KFX94217.1 - 0.0013 17.6 0.1 0.0021 16.8 0.1 1.2 1 0 0 1 1 1 1 Sigma NS protein DUF1664 PF07889.12 KFX94217.1 - 0.0029 17.6 0.3 0.034 14.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) DUF2920 PF11144.8 KFX94217.1 - 0.019 14.1 0.1 29 3.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2920) Laminin_II PF06009.12 KFX94217.1 - 0.022 14.8 1.5 0.089 12.8 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF2087 PF09860.9 KFX94217.1 - 0.047 13.8 0.0 3 8.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Phage_term_smal PF05944.12 KFX94217.1 - 0.05 13.6 0.0 0.92 9.5 0.0 2.5 3 0 0 3 3 3 0 Phage small terminase subunit DUF4200 PF13863.6 KFX94217.1 - 0.053 13.9 0.7 0.12 12.8 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KFX94217.1 - 0.065 12.1 1.8 0.24 10.2 1.8 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PTPA PF03095.15 KFX94217.1 - 0.079 12.4 0.1 0.39 10.1 0.1 2.0 1 1 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein COG6 PF06419.11 KFX94217.1 - 0.097 10.9 3.3 0.078 11.2 0.7 2.0 2 1 0 2 2 2 0 Conserved oligomeric complex COG6 ATR13 PF16829.5 KFX94217.1 - 0.11 12.9 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Helo_like_N PF17111.5 KFX94217.1 - 0.16 11.3 2.5 0.56 9.5 2.5 1.9 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Syntaxin-6_N PF09177.11 KFX94217.1 - 0.2 12.2 1.5 0.6 10.7 0.5 2.4 3 1 0 3 3 2 0 Syntaxin 6, N-terminal Ribosomal_60s PF00428.19 KFX94218.1 - 3.6e-25 88.4 8.5 5.2e-25 87.9 8.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FERM_F1 PF18379.1 KFX94218.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain Auxin_canalis PF05703.11 KFX94219.1 - 0.022 14.7 1.0 0.022 14.7 1.0 1.5 2 0 0 2 2 2 0 Auxin canalisation Pex19 PF04614.12 KFX94220.1 - 1.9e-74 250.5 13.2 1.9e-74 250.5 13.2 2.1 2 1 0 2 2 2 1 Pex19 protein family LUD_dom PF02589.15 KFX94220.1 - 0.00019 21.2 0.7 0.0003 20.6 0.7 1.3 1 0 0 1 1 1 1 LUD domain Vps4_C PF09336.10 KFX94220.1 - 0.025 14.6 0.1 0.093 12.7 0.1 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain EspB PF05802.11 KFX94220.1 - 0.031 14.2 8.0 3.4 7.6 4.6 3.0 2 1 0 2 2 2 0 Enterobacterial EspB protein GlutR_dimer PF00745.20 KFX94220.1 - 0.095 13.2 1.0 0.28 11.7 1.0 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain dsDNA_bind PF01984.20 KFX94220.1 - 0.5 10.6 3.0 2 8.8 1.4 2.5 1 1 1 2 2 2 0 Double-stranded DNA-binding domain FliE PF02049.18 KFX94220.1 - 0.56 10.4 10.8 0.082 13.1 3.0 3.4 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE DUF573 PF04504.14 KFX94220.1 - 0.61 10.8 2.9 4.1 8.1 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function, DUF573 UQ_con PF00179.26 KFX94221.1 - 2.5e-49 166.5 0.0 2.8e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX94221.1 - 0.00041 20.1 0.0 0.00048 19.8 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFX94221.1 - 0.16 12.2 0.8 0.27 11.5 0.8 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 KFX94222.1 - 9.4e-95 318.3 0.1 7.3e-56 190.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KFX94222.1 - 3.6e-36 123.8 0.0 8e-36 122.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFX94222.1 - 4.4e-28 98.1 0.0 3.9e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFX94222.1 - 6.1e-09 35.7 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFX94222.1 - 0.0033 16.6 0.0 0.0085 15.2 0.0 1.7 1 1 0 1 1 1 1 NAD synthase IBR PF01485.21 KFX94223.1 - 5.8e-09 36.0 53.8 6.5e-05 23.1 10.2 6.1 5 2 0 5 5 5 3 IBR domain, a half RING-finger domain Fer2_3 PF13085.6 KFX94223.1 - 3.1 7.8 9.7 0.26 11.3 2.8 2.7 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF1712 PF08217.11 KFX94224.1 - 1.9e-15 56.4 0.0 4.7e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 KFX94225.1 - 5.5e-22 78.4 0.0 8.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.32 KFX94226.1 - 5.1e-41 137.9 24.2 4.1e-10 40.1 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94226.1 - 1.2e-12 47.9 1.5 0.003 17.8 0.1 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX94226.1 - 5.5e-08 32.1 0.1 0.2 10.6 0.0 4.5 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX94226.1 - 4.4e-07 28.9 3.8 0.021 13.5 0.1 4.6 4 1 1 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFX94226.1 - 2.4e-06 26.7 0.1 2.4e-06 26.7 0.1 2.9 4 1 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFX94226.1 - 0.00091 17.7 0.0 0.0017 16.8 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 KFX94226.1 - 0.0081 15.7 0.0 0.027 14.0 0.0 1.9 1 1 1 2 2 2 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 KFX94226.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Hira PF07569.11 KFX94226.1 - 0.051 13.3 0.6 1 9.1 0.5 2.9 1 1 1 2 2 2 0 TUP1-like enhancer of split CPSF_A PF03178.15 KFX94226.1 - 0.081 12.2 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region Spc7 PF08317.11 KFX94227.1 - 0.0048 15.8 0.2 0.01 14.7 0.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KFX94227.1 - 0.059 14.0 4.9 0.23 12.1 0.3 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 KFX94227.1 - 0.065 12.6 3.2 0.053 12.9 0.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 KFX94227.1 - 0.11 12.8 0.5 0.25 11.7 0.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 KFX94227.1 - 0.21 11.8 2.3 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding betaPIX_CC PF16523.5 KFX94227.1 - 0.27 11.1 1.4 19 5.2 0.1 2.7 1 1 1 2 2 2 0 betaPIX coiled coil FYVE_2 PF02318.16 KFX94227.1 - 0.49 10.6 2.0 1.3 9.3 2.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ly49 PF08391.10 KFX94227.1 - 0.79 10.1 6.7 0.071 13.5 1.3 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region ADIP PF11559.8 KFX94227.1 - 0.99 9.5 7.1 0.18 11.9 1.5 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HemX PF04375.14 KFX94227.1 - 1.3 8.2 3.5 0.67 9.2 0.1 1.9 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase HR1 PF02185.16 KFX94227.1 - 2.7 8.2 4.9 3.7 7.7 0.4 2.4 2 0 0 2 2 2 0 Hr1 repeat UPF0242 PF06785.11 KFX94227.1 - 5.1 7.2 5.7 0.64 10.1 0.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SUR7 PF06687.12 KFX94229.1 - 2e-25 89.7 12.7 2.5e-25 89.4 12.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fumarate_red_D PF02313.17 KFX94229.1 - 1.5 9.0 7.3 0.09 12.9 1.6 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit D HILPDA PF15220.6 KFX94229.1 - 2.8 8.1 5.7 0.66 10.1 0.8 2.3 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated Helicase_C PF00271.31 KFX94230.1 - 4.4e-09 36.7 0.2 8e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RhlB PF12300.8 KFX94230.1 - 0.75 9.9 6.8 0.96 9.6 6.8 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB GRP PF07172.11 KFX94230.1 - 0.92 10.2 23.0 0.53 11.0 21.5 1.4 1 1 0 1 1 1 0 Glycine rich protein family FoP_duplication PF13865.6 KFX94230.1 - 2.2 8.9 9.6 0.47 11.0 6.0 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 F_actin_cap_B PF01115.17 KFX94232.1 - 1.2e-101 339.3 0.0 1.4e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Epimerase PF01370.21 KFX94234.1 - 3.5e-20 72.5 0.0 5.3e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX94234.1 - 2.8e-08 33.2 0.1 3.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX94234.1 - 2.4e-07 30.5 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX94234.1 - 4.7e-06 25.8 0.0 8e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX94234.1 - 0.00035 20.5 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFX94234.1 - 0.004 16.6 0.0 0.017 14.6 0.0 2.0 1 1 1 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX94234.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KFX94234.1 - 0.02 15.0 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KFX94234.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Topoisom_I PF01028.20 KFX94235.1 - 1.3e-96 322.4 4.7 1.3e-96 322.4 4.7 1.9 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFX94235.1 - 4.8e-95 317.1 1.2 4.8e-95 317.1 1.2 4.2 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFX94235.1 - 3e-32 110.3 0.4 1.1e-31 108.6 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Rab_bind PF16704.5 KFX94235.1 - 0.0059 16.6 1.2 0.015 15.3 0.1 2.3 3 0 0 3 3 3 1 Rab binding domain Csm1_N PF18504.1 KFX94235.1 - 0.0075 16.6 2.3 0.0075 16.6 2.3 3.4 3 1 0 3 3 3 1 Csm1 N-terminal domain ATP-synt PF00231.19 KFX94236.1 - 7.5e-77 258.8 8.4 9.1e-77 258.5 8.4 1.0 1 0 0 1 1 1 1 ATP synthase Cation_ATPase_C PF00689.21 KFX94237.1 - 9.7e-32 110.1 2.6 9.7e-32 110.1 2.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX94237.1 - 1.4e-30 106.2 24.1 4.6e-26 91.5 0.4 3.7 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 KFX94237.1 - 8.1e-21 73.9 0.0 2e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX94237.1 - 4.5e-19 69.6 2.9 1.6e-17 64.5 2.9 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX94237.1 - 2.5e-12 46.3 0.0 7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX94237.1 - 1.9e-05 24.5 0.4 0.0028 17.4 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoatB PF10389.9 KFX94237.1 - 0.22 11.4 2.4 0.96 9.3 2.4 2.2 1 0 0 1 1 1 0 Bacteriophage coat protein B MFS_1 PF07690.16 KFX94255.1 - 4e-21 75.3 65.3 2.6e-20 72.7 35.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_C PF12025.8 KFX94255.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein C OATP PF03137.20 KFX94255.1 - 0.46 8.7 11.2 0.019 13.3 2.8 2.4 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Trp_oprn_chp PF09534.10 KFX94255.1 - 8.8 6.1 7.2 1.8 8.4 2.4 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PAP_central PF04928.17 KFX94256.1 - 1.3e-110 368.3 0.0 1.7e-110 367.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFX94256.1 - 9.4e-63 210.9 0.3 4.4e-62 208.7 0.3 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFX94256.1 - 1.3e-08 35.0 0.0 1.3e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KFX94256.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DnaJ PF00226.31 KFX94257.1 - 7.8e-16 58.0 1.4 1.8e-15 56.8 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFX94257.1 - 2.8e-10 39.8 0.0 2e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain Methyltr_RsmB-F PF01189.17 KFX94259.1 - 9.7e-14 51.5 0.3 1.6e-07 31.2 0.1 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Nop16 PF09420.10 KFX94259.1 - 0.14 12.2 3.2 0.087 12.9 0.4 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Pkinase PF00069.25 KFX94261.1 - 2.6e-76 256.5 0.0 3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94261.1 - 1.8e-35 122.5 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX94261.1 - 0.00019 20.5 0.0 0.0018 17.3 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFX94261.1 - 0.083 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX94261.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like SSrecog PF03531.14 KFX94262.1 - 9.1e-31 105.6 0.2 1.1e-29 102.2 0.0 2.8 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KFX94262.1 - 1.8e-29 102.0 1.3 8.4e-29 99.9 0.5 2.4 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFX94262.1 - 7.1e-24 84.0 0.1 8.4e-23 80.6 0.0 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like CTNNB1_binding PF08347.11 KFX94262.1 - 0.024 14.8 0.5 0.056 13.6 0.5 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding HSP90 PF00183.18 KFX94263.1 - 1.2e-219 730.5 27.5 1.5e-219 730.2 27.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFX94263.1 - 2e-14 54.0 0.1 3.6e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFX94263.1 - 6.5e-09 35.7 0.1 2.2e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KFX94263.1 - 0.55 10.2 6.1 0.69 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Flavin_Reduct PF01613.18 KFX94264.1 - 8.2e-25 87.7 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.18 KFX94265.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.10 KFX94266.1 - 1.2e-85 286.8 2.2 1.2e-85 286.8 2.2 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KFX94266.1 - 2.7e-24 85.3 0.0 5.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.9 KFX94266.1 - 0.0095 15.1 0.5 0.016 14.4 0.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFX94266.1 - 0.016 14.9 3.3 0.24 11.1 0.6 2.4 1 1 1 2 2 2 0 BAR domain of APPL family Med11 PF10280.9 KFX94267.1 - 7.5e-42 143.0 0.4 9.9e-42 142.7 0.4 1.2 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 KFX94268.1 - 2.5e-44 148.4 28.3 3.2e-08 34.1 0.5 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFX94268.1 - 7.9e-40 136.1 0.9 1.2e-39 135.5 0.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFX94268.1 - 6.9e-10 39.1 1.2 0.27 11.6 0.1 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX94268.1 - 9.5e-06 24.5 0.1 0.037 12.7 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.11 KFX94268.1 - 4.1e-05 23.4 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 KFX94268.1 - 0.00049 19.0 0.2 0.73 8.5 0.0 3.5 2 2 1 3 3 3 2 Nup133 N terminal like RAB3GAP2_N PF14655.6 KFX94268.1 - 0.00085 18.7 0.0 3.9 6.6 0.0 3.3 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KFX94268.1 - 0.01 14.8 2.0 11 4.9 0.1 3.6 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2976 PF11190.8 KFX94269.1 - 0.011 15.6 0.1 0.024 14.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) Scs3p PF10261.9 KFX94270.1 - 7.9e-71 238.4 1.7 1.1e-70 238.0 1.7 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Ras PF00071.22 KFX94271.1 - 5.4e-57 191.9 0.0 6.5e-57 191.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX94271.1 - 1.6e-33 115.4 0.0 2.2e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX94271.1 - 8.8e-14 51.3 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX94271.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFX94271.1 - 1.6e-05 24.4 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX94271.1 - 0.00018 21.6 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX94271.1 - 0.00081 19.8 0.1 0.0016 18.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX94271.1 - 0.037 13.9 0.1 2.1 8.2 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase BetaGal_dom4_5 PF13364.6 KFX94271.1 - 0.057 14.0 0.0 3.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain Kri1_C PF12936.7 KFX94272.1 - 5.4e-32 109.8 0.8 5.4e-32 109.8 0.8 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 KFX94272.1 - 3e-26 92.0 13.8 3e-26 92.0 13.8 5.2 5 1 0 5 5 5 1 KRI1-like family Clr2_transil PF16761.5 KFX94280.1 - 7.4e-15 55.5 0.5 1.7e-14 54.4 0.5 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KFX94280.1 - 2e-09 38.4 0.0 9.5e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Sec61_beta PF03911.16 KFX94281.1 - 4.8e-18 64.9 2.6 4.8e-18 64.9 2.6 1.7 2 0 0 2 2 2 1 Sec61beta family DUF1180 PF06679.12 KFX94281.1 - 0.11 12.9 1.2 0.14 12.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.18 KFX94282.1 - 9.2e-54 181.4 0.1 1.4e-53 180.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.32 KFX94283.1 - 7e-13 48.8 0.0 0.032 15.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94283.1 - 8.9e-05 22.7 0.0 0.82 10.0 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFX94283.1 - 9e-05 21.2 0.0 0.00014 20.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Sel1 PF08238.12 KFX94284.1 - 2.8e-32 110.4 37.5 7.8e-05 23.2 0.6 12.1 12 1 1 13 13 13 9 Sel1 repeat TPR_7 PF13176.6 KFX94284.1 - 3.5e-05 23.5 3.1 15 5.9 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX94284.1 - 0.27 11.8 6.2 0.39 11.3 1.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX94284.1 - 0.28 11.6 5.9 6.8 7.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX94284.1 - 9.5 7.1 20.0 20 6.1 0.0 7.5 8 2 0 8 8 8 0 Tetratricopeptide repeat Methyltransf_2 PF00891.18 KFX94285.1 - 4e-17 62.2 0.0 6.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF4345 PF14248.6 KFX94286.1 - 1.8 8.5 7.8 2.6 8.0 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Rad1 PF02144.16 KFX94287.1 - 7.1e-76 254.9 0.9 9.2e-76 254.5 0.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KFX94287.1 - 1.3e-10 41.4 3.3 1.3e-10 41.4 3.3 2.5 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit 5 Bromodomain PF00439.25 KFX94288.1 - 1.8e-24 85.6 0.5 4.6e-24 84.3 0.5 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFX94288.1 - 7.3e-08 32.7 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX94288.1 - 1.8e-07 31.1 0.4 9.9e-07 28.8 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX94288.1 - 0.00033 21.0 0.4 0.00066 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX94288.1 - 0.21 11.6 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_membrane_2 PF06472.15 KFX94289.1 - 1.2e-90 303.6 1.2 2.3e-88 296.1 0.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFX94289.1 - 4e-14 53.3 0.0 1.1e-13 51.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFX94289.1 - 0.029 14.2 0.0 0.098 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DnaJ_C PF01556.18 KFX94290.1 - 3.6e-36 124.5 0.6 4.2e-36 124.2 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain Glyco_hydro_18 PF00704.28 KFX94292.1 - 2.8e-51 175.1 2.1 4.5e-51 174.4 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX94292.1 - 5e-07 29.7 0.2 0.026 14.6 0.0 3.6 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.19 KFX94292.1 - 8.2e-07 29.4 9.7 8.2e-07 29.4 9.7 2.8 3 0 0 3 3 3 1 Chitin recognition protein Varsurf_PPLC PF03490.13 KFX94292.1 - 0.0072 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Methyltransf_10 PF05971.12 KFX94299.1 - 2.6e-35 122.2 0.0 3.3e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 KFX94299.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KFX94299.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.6 KFX94299.1 - 0.053 13.3 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFX94299.1 - 0.061 14.1 0.0 0.29 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFX94299.1 - 0.064 13.9 0.0 0.29 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MAP PF03642.13 KFX94299.1 - 0.076 13.3 0.2 0.48 10.8 0.1 2.1 2 1 0 2 2 2 0 MAP domain MTS PF05175.14 KFX94299.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KFX94299.1 - 0.19 12.5 0.0 0.5 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ank_4 PF13637.6 KFX94300.1 - 7.8e-48 160.3 6.2 2.5e-09 37.5 0.0 9.6 6 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX94300.1 - 1.7e-47 159.9 5.3 1.5e-11 44.7 0.1 7.1 5 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX94300.1 - 1.5e-34 117.5 12.4 4.3e-08 33.3 0.4 8.0 7 1 2 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94300.1 - 6.5e-33 109.1 12.0 0.00012 22.2 0.0 12.1 12 1 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 KFX94300.1 - 1.8e-31 107.2 28.0 0.00016 22.0 0.3 11.3 11 1 0 11 11 11 8 Ankyrin repeat F-box-like PF12937.7 KFX94300.1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like GLTP PF08718.11 KFX94301.1 - 1.9e-46 158.1 0.0 2.5e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PLDc PF00614.22 KFX94302.1 - 2.1e-15 56.1 2.2 1.6e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFX94302.1 - 2.6e-15 56.5 0.0 2e-05 24.5 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain Sugar_tr PF00083.24 KFX94303.1 - 1.3e-36 126.5 23.7 1.5e-35 122.9 23.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94303.1 - 2.5e-27 95.7 30.3 4.9e-21 75.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ldh_1_N PF00056.23 KFX94304.1 - 7.9e-45 152.4 0.1 2.1e-44 151.0 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFX94304.1 - 2.3e-44 151.3 0.1 6e-44 149.9 0.3 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KFX94304.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2OG-FeII_Oxy_3 PF13640.6 KFX94305.1 - 2.1e-11 44.5 0.0 3.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KFX94305.1 - 0.0019 18.6 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.21 KFX94321.1 - 3.9e-59 200.7 0.0 4.3e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CPT PF07931.12 KFX94322.1 - 4e-05 23.5 0.0 7.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KFX94322.1 - 0.0037 17.8 0.0 0.046 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 KFX94322.1 - 0.032 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KFX94322.1 - 0.036 14.4 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KFX94322.1 - 0.041 14.1 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KFX94322.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase G-alpha PF00503.20 KFX94322.1 - 0.22 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Gly_transf_sug PF04488.15 KFX94325.1 - 3.7e-14 53.1 0.0 7.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif C2 PF00168.30 KFX94336.1 - 2.9e-16 59.6 0.0 4.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain ICL PF00463.21 KFX94337.1 - 1.5e-292 970.8 1.2 1.7e-292 970.6 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFX94337.1 - 3.9e-11 42.9 0.1 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2753 PF10952.8 KFX94338.1 - 0.062 13.4 0.0 0.61 10.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2753) DivIC PF04977.15 KFX94340.1 - 3.2 7.6 5.6 6 6.7 5.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Mid2 PF04478.12 KFX94341.1 - 7.5e-06 25.8 0.6 7.5e-06 25.8 0.6 2.3 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor Apt1 PF10351.9 KFX94341.1 - 0.018 13.9 9.1 0.02 13.8 9.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4381 PF14316.6 KFX94341.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Presenilin PF01080.17 KFX94341.1 - 0.053 12.3 1.7 0.071 11.9 1.7 1.4 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 KFX94341.1 - 0.09 11.3 5.0 0.096 11.3 5.0 1.1 1 0 0 1 1 1 0 Utp14 protein SKG6 PF08693.10 KFX94341.1 - 0.11 11.9 2.1 0.39 10.2 2.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SOG2 PF10428.9 KFX94341.1 - 0.46 9.6 24.0 0.66 9.1 24.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ketoacyl-synt PF00109.26 KFX94349.1 - 2e-31 109.5 0.0 3.3e-20 72.7 0.0 2.0 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain DUF4746 PF15928.5 KFX94350.1 - 0.023 14.1 1.6 0.033 13.6 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) UPF0242 PF06785.11 KFX94350.1 - 0.47 10.5 5.6 0.82 9.7 5.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Noggin PF05806.12 KFX94350.1 - 5.7 6.8 10.2 0.056 13.4 2.4 1.5 2 0 0 2 2 2 0 Noggin DUF2040 PF09745.9 KFX94351.1 - 4.8e-36 123.5 17.7 4.8e-36 123.5 17.7 3.1 3 1 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) LDB19 PF13002.7 KFX94352.1 - 2.6e-12 46.9 0.0 4.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 KFX94352.1 - 0.0048 17.0 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF2492 PF10678.9 KFX94358.1 - 0.15 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF2492 PF10678.9 KFX94363.1 - 0.062 13.6 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) Suc_Fer-like PF06999.12 KFX94366.1 - 1.2e-43 149.3 0.0 1.4e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PhoLip_ATPase_C PF16212.5 KFX94367.1 - 4.6e-47 160.9 11.9 4.6e-47 160.9 11.9 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX94367.1 - 3e-16 58.8 0.1 6.5e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFX94367.1 - 5.1e-13 49.8 2.9 8.6e-07 29.5 2.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX94367.1 - 4e-06 26.8 0.0 9.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFX94367.1 - 2e-05 24.2 3.8 0.0047 16.5 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX94367.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 KFX94367.1 - 0.22 11.5 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sec16_C PF12931.7 KFX94368.1 - 5.2e-111 371.1 0.0 7e-111 370.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFX94368.1 - 2e-34 118.7 0.0 6e-34 117.2 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KFX94368.1 - 4.5e-12 46.7 9.9 4.5e-12 46.7 9.9 3.2 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus Tim54 PF11711.8 KFX94368.1 - 0.71 8.6 3.3 41 2.8 0.0 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAD_binding_4 PF01565.23 KFX94369.1 - 5e-17 61.9 0.0 8.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-DNL PF05180.12 KFX94370.1 - 0.00028 20.8 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger Paralemmin PF03285.15 KFX94370.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Paralemmin Pkinase PF00069.25 KFX94372.1 - 6.1e-67 225.8 0.7 3.6e-66 223.2 0.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94372.1 - 2.1e-51 174.7 0.3 4.8e-51 173.5 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KFX94372.1 - 1.1e-22 80.1 0.1 3.7e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain HGTP_anticodon PF03129.20 KFX94372.1 - 1.1e-18 67.2 0.1 5.2e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFX94372.1 - 5.8e-07 29.7 0.0 4.9e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Kinase-like PF14531.6 KFX94372.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX94372.1 - 3.5e-05 22.8 0.0 3.5e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 KFX94372.1 - 0.00062 20.2 0.0 0.0018 18.7 0.0 1.9 1 0 0 1 1 1 1 PH domain APH PF01636.23 KFX94372.1 - 0.026 14.5 0.2 0.026 14.5 0.2 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFX94372.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFX94372.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Brix PF04427.18 KFX94373.1 - 6.4e-12 46.0 0.0 9.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain SH3_1 PF00018.28 KFX94377.1 - 2.5e-05 23.8 0.0 6.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX94377.1 - 0.037 13.9 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain GFA PF04828.14 KFX94378.1 - 4e-19 68.7 0.0 5.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADH_N PF08240.12 KFX94379.1 - 1.4e-27 95.7 2.0 2.8e-27 94.7 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX94379.1 - 2e-19 69.9 0.0 4.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX94379.1 - 0.0015 19.6 0.0 0.0038 18.3 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KFX94379.1 - 0.0016 18.2 1.1 0.0064 16.2 0.5 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KFX94379.1 - 0.011 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFX94379.1 - 0.019 14.3 1.8 0.021 14.1 0.9 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PalH PF08733.10 KFX94383.1 - 4.8e-88 295.3 1.7 6.1e-88 295.0 1.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 BNR_4 PF15892.5 KFX94393.1 - 1.1e-66 225.0 8.7 3.1e-66 223.5 8.7 1.7 1 1 0 1 1 1 1 BNR repeat-containing family member Sugar_tr PF00083.24 KFX94393.1 - 3e-64 217.5 28.4 3.7e-64 217.3 28.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94393.1 - 5.2e-13 48.6 38.0 2e-06 27.0 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KFX94393.1 - 8.5 4.5 13.2 16 3.6 13.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TPR_10 PF13374.6 KFX94394.1 - 2.2e-43 145.0 8.9 2.1e-12 46.5 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat SesA PF17107.5 KFX94394.1 - 1.1e-37 129.0 0.0 3.7e-37 127.2 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_12 PF13424.6 KFX94394.1 - 2e-34 117.7 1.7 6.7e-15 55.1 0.3 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX94394.1 - 6.3e-14 50.9 4.6 0.015 15.2 0.0 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat NACHT PF05729.12 KFX94394.1 - 9.1e-08 32.2 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.14 KFX94394.1 - 1.1e-07 31.7 2.5 4.3 8.3 0.1 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat Dynamin_N PF00350.23 KFX94394.1 - 3e-07 30.7 0.0 7.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family TPR_17 PF13431.6 KFX94394.1 - 9.7e-07 28.8 5.3 0.26 11.7 0.1 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX94394.1 - 1.5e-06 28.7 0.2 1.5 9.5 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX94394.1 - 6.5e-06 26.0 5.9 0.99 9.8 0.0 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX94394.1 - 9.4e-06 25.2 6.3 1.3 9.0 0.0 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX94394.1 - 1.7e-05 24.6 5.1 2.6 8.4 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX94394.1 - 4.7e-05 23.8 3.6 1.6 9.3 0.0 5.0 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX94394.1 - 9.3e-05 21.9 4.9 0.0014 18.1 4.5 2.5 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 KFX94394.1 - 0.022 15.6 2.7 14 6.8 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Arteri_nsp7a PF16749.5 KFX94394.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha RNA_helicase PF00910.22 KFX94394.1 - 0.067 13.6 0.0 0.68 10.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KFX94397.1 - 2.1e-42 144.9 0.0 3.2e-21 76.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX94397.1 - 1.7e-34 119.8 26.2 2.2e-21 76.7 11.3 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region T2SSE PF00437.20 KFX94397.1 - 1.5e-09 37.3 0.3 0.0005 19.2 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFX94397.1 - 8.7e-09 35.0 0.5 0.0016 18.1 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFX94397.1 - 2.7e-08 33.5 0.6 0.0039 16.7 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX94397.1 - 4.9e-08 33.1 0.4 0.39 10.5 0.0 3.6 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX94397.1 - 1.6e-07 31.7 0.1 0.022 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KFX94397.1 - 1.8e-06 28.5 0.3 0.058 13.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFX94397.1 - 6.4e-06 25.7 0.1 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KFX94397.1 - 8.5e-06 25.8 1.0 0.091 12.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KFX94397.1 - 2e-05 24.8 0.0 0.29 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KFX94397.1 - 2e-05 25.2 0.1 0.067 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFX94397.1 - 7.1e-05 22.9 0.1 0.27 11.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KFX94397.1 - 9.9e-05 22.0 2.3 0.039 13.5 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFX94397.1 - 0.00043 20.2 0.2 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.12 KFX94397.1 - 0.00079 18.8 1.1 1.7 7.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.6 KFX94397.1 - 0.0013 19.3 1.2 2.8 8.5 0.2 3.0 3 0 0 3 3 2 2 AAA domain Adeno_IVa2 PF02456.15 KFX94397.1 - 0.0013 17.6 0.2 0.083 11.7 0.1 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein ATPase_2 PF01637.18 KFX94397.1 - 0.0016 18.4 0.1 3.3 7.6 0.0 3.5 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KFX94397.1 - 0.0025 17.9 0.5 1.5 8.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 KFX94397.1 - 0.0032 17.0 0.3 0.66 9.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX94397.1 - 0.0036 16.8 0.4 0.6 9.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KFX94397.1 - 0.0038 17.3 0.1 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 KFX94397.1 - 0.0039 16.1 1.0 0.56 8.9 0.0 3.4 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_24 PF13479.6 KFX94397.1 - 0.0052 16.5 0.1 0.6 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX94397.1 - 0.0058 16.6 2.6 2.4 8.0 0.1 3.1 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 KFX94397.1 - 0.0066 16.2 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFX94397.1 - 0.0071 16.1 0.1 3.7 7.2 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KFX94397.1 - 0.01 15.8 1.3 0.44 10.4 0.0 2.9 3 0 0 3 3 2 0 Rad17 P-loop domain TsaE PF02367.17 KFX94397.1 - 0.011 15.7 0.5 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KFX94397.1 - 0.013 15.2 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.13 KFX94397.1 - 0.023 13.9 0.3 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Pox_A32 PF04665.12 KFX94397.1 - 0.023 14.1 0.2 4 6.8 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 KFX94397.1 - 0.025 15.0 0.0 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KFX94397.1 - 0.028 13.8 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 KFX94397.1 - 0.033 14.0 0.4 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 KFX94397.1 - 0.042 13.0 3.5 2.7 7.1 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 KFX94397.1 - 0.044 13.8 1.3 22 5.0 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 KFX94397.1 - 0.063 12.2 0.4 5.1 5.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.18 KFX94397.1 - 0.084 12.1 0.2 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Septin dNK PF01712.19 KFX94397.1 - 0.09 12.6 0.7 3.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 KFX94397.1 - 0.093 12.5 0.5 4.5 7.0 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA PF00004.29 KFX94397.1 - 0.11 12.9 0.2 4.2 7.8 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KFX94397.1 - 0.14 11.9 0.2 7.2 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KFX94397.1 - 0.14 11.9 1.1 18 5.0 0.3 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.20 KFX94397.1 - 0.15 11.9 0.8 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KFX94397.1 - 0.18 11.0 0.6 18 4.4 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KFX94397.1 - 0.49 10.5 1.9 2.1 8.4 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain PHF5 PF03660.14 KFX94399.1 - 0.038 14.2 0.8 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 PHF5-like protein Transp_cyt_pur PF02133.15 KFX94402.1 - 6.8e-48 163.5 34.2 7.9e-48 163.3 34.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3040 PF11239.8 KFX94402.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.6 4 1 2 6 6 6 0 Protein of unknown function (DUF3040) Na_sulph_symp PF00939.19 KFX94404.1 - 6.6e-20 71.6 32.2 3.5e-19 69.2 32.2 1.9 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFX94404.1 - 8.5e-17 61.3 66.3 9.8e-13 48.0 37.9 2.1 1 1 1 2 2 2 2 Citrate transporter DUF488 PF04343.13 KFX94405.1 - 2.2e-18 67.0 0.0 4.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF488 RGS_DHEX PF18148.1 KFX94405.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain HLH PF00010.26 KFX94416.1 - 7.3e-16 57.9 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAS PF13851.6 KFX94416.1 - 0.0096 15.3 0.2 0.017 14.5 0.2 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Smac_DIABLO PF09057.10 KFX94416.1 - 0.039 13.3 4.3 0.057 12.8 4.3 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Goodbye PF17109.5 KFX94416.1 - 0.04 14.4 0.5 0.55 10.7 0.6 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain ZapB PF06005.12 KFX94416.1 - 0.2 12.1 2.4 0.61 10.6 0.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Trimer_CC PF08954.11 KFX94421.1 - 0.15 11.6 0.1 0.15 11.6 0.1 1.9 3 0 0 3 3 3 0 Trimerisation motif GCN5L1 PF06320.13 KFX94426.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) PHD PF00628.29 KFX94426.1 - 0.068 13.1 10.8 0.19 11.7 10.8 1.8 1 1 0 1 1 1 0 PHD-finger DOCK_N PF16172.5 KFX94427.1 - 1.7e-122 409.0 0.6 2.4e-122 408.5 0.6 1.2 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFX94427.1 - 1.4e-40 139.2 0.0 3.7e-40 137.8 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KFX94427.1 - 4.4e-34 118.0 2.0 3.6e-33 115.0 2.0 2.1 1 1 0 1 1 1 1 Dock homology region 2 SH3_9 PF14604.6 KFX94427.1 - 0.00024 20.9 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFX94427.1 - 0.0004 19.9 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ADH_zinc_N_2 PF13602.6 KFX94428.1 - 4.6e-09 37.4 0.0 1.1e-08 36.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX94428.1 - 7.4e-09 35.5 0.0 2.2e-08 33.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX94428.1 - 0.0031 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.22 KFX94428.1 - 0.1 12.5 1.5 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 Biotin-requiring enzyme Acyl_transf_3 PF01757.22 KFX94429.1 - 4.8e-31 108.1 36.7 1.3e-30 106.6 36.7 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF4239 PF14023.6 KFX94429.1 - 0.096 12.4 2.0 0.22 11.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Isochorismatase PF00857.20 KFX94438.1 - 5.2e-20 72.4 0.0 8.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Cytochrom_B561 PF03188.16 KFX94438.1 - 4.4e-07 30.1 9.6 8.5e-07 29.2 9.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KFX94438.1 - 1.1e-06 28.4 3.3 2.8e-06 27.1 3.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KFX94438.1 - 2 8.6 11.6 0.46 10.6 5.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Zn_clus PF00172.18 KFX94439.1 - 6.2e-10 39.0 12.1 1.2e-09 38.1 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX94439.1 - 7.5e-05 21.9 0.7 0.00019 20.6 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prion PF00377.18 KFX94439.1 - 0.058 13.2 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain DUF4441 PF14536.6 KFX94439.1 - 0.14 12.3 0.2 0.37 11.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) p450 PF00067.22 KFX94440.1 - 4.3e-45 154.3 0.0 7.6e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2263 PF10021.9 KFX94440.1 - 1.6e-22 80.5 0.0 3.3e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KFX94440.1 - 0.0071 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 Macro domain DUF5615 PF18480.1 KFX94440.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Zip PF02535.22 KFX94441.1 - 2.3e-50 171.7 2.1 3.5e-50 171.1 2.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter p450 PF00067.22 KFX94442.1 - 4.9e-69 233.3 0.0 6.9e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 OrsD PF12013.8 KFX94442.1 - 8.1e-23 81.0 1.0 1.8e-22 79.9 1.0 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fungal_trans_2 PF11951.8 KFX94442.1 - 1.1e-05 24.5 0.2 3.3e-05 22.9 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain AXE1 PF05448.12 KFX94443.1 - 1.8e-05 23.6 0.0 6.6e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFX94443.1 - 7.6e-05 22.3 0.0 0.00048 19.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KFX94443.1 - 0.00011 22.9 0.1 0.00016 22.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.11 KFX94443.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 KFX94443.1 - 0.00024 20.4 0.0 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KFX94443.1 - 0.00058 19.5 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KFX94443.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KFX94443.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Carn_acyltransf PF00755.20 KFX94444.1 - 8.7e-124 414.3 0.0 1.1e-123 414.0 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.21 KFX94444.1 - 3e-41 142.0 0.0 5.9e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 KFX94444.1 - 2e-07 31.3 0.0 1.1e-06 28.9 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Alpha-amylase PF00128.24 KFX94445.1 - 2.8e-57 194.8 0.0 3.8e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KFX94445.1 - 4.1e-14 52.6 0.1 1.1e-13 51.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) ABC2_membrane PF01061.24 KFX94445.1 - 0.14 11.6 0.1 0.36 10.2 0.1 1.6 1 0 0 1 1 1 0 ABC-2 type transporter Glyco_hydro_15 PF00723.21 KFX94446.1 - 6.8e-99 331.7 0.2 7.8e-99 331.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CDH-cyt PF16010.5 KFX94447.1 - 4.2e-49 166.7 0.7 8.4e-49 165.7 0.7 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KFX94447.1 - 1e-24 87.5 0.0 1e-23 84.1 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX94447.1 - 9.8e-20 71.5 0.0 9.8e-20 71.5 0.0 1.9 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX94447.1 - 3.8e-09 36.1 0.0 7.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX94447.1 - 0.00031 20.4 0.1 0.0094 15.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX94447.1 - 0.0007 18.9 0.3 0.0016 17.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX94447.1 - 0.0015 17.9 0.0 0.059 12.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94447.1 - 0.0016 18.6 0.0 0.0056 16.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX94447.1 - 0.0037 17.8 0.1 0.34 11.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX94447.1 - 0.0062 15.3 0.1 0.0099 14.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFX94447.1 - 0.056 12.8 0.4 0.17 11.2 0.6 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX94447.1 - 0.095 11.9 0.8 0.15 11.2 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KFX94447.1 - 0.11 11.5 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein LPMO_10 PF03067.15 KFX94448.1 - 3.3e-08 34.4 3.7 6.5e-08 33.5 3.7 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading adh_short PF00106.25 KFX94449.1 - 5.8e-16 58.5 0.0 1.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KFX94449.1 - 1.4e-08 34.9 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX94449.1 - 1.3e-06 28.2 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFX94449.1 - 0.0025 17.3 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HeLo PF14479.6 KFX94450.1 - 1.6e-16 60.8 0.0 1.7e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank_2 PF12796.7 KFX94451.1 - 3.2e-06 27.6 0.0 5.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94451.1 - 3.4e-06 27.5 0.1 0.00048 20.6 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX94451.1 - 4.3e-06 26.9 0.0 8.9e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFX94451.1 - 5.5e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94451.1 - 8e-05 22.8 0.0 0.00067 19.9 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Cupin_2 PF07883.11 KFX94452.1 - 0.0072 16.0 4.1 0.77 9.5 0.1 3.4 3 1 0 3 3 3 2 Cupin domain PMI_typeI PF01238.21 KFX94452.1 - 0.0098 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomannose isomerase type I Mannosidase_ig PF17786.1 KFX94453.1 - 8.5e-16 58.4 0.1 2.1e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFX94453.1 - 2.1e-09 38.0 0.0 5.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFX94453.1 - 0.00024 20.8 1.4 0.00064 19.4 0.0 2.4 3 0 0 3 3 3 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KFX94453.1 - 0.0027 17.6 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 KFX94454.1 - 1.3e-77 261.6 22.7 2.4e-77 260.8 22.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94454.1 - 1.2e-16 60.6 20.9 1.2e-16 60.6 20.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KFX94455.1 - 9.1e-08 32.1 12.2 1.7e-07 31.2 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX94455.1 - 1.6e-07 30.5 4.6 1.1e-06 27.7 4.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KFX94455.1 - 0.016 14.2 0.4 0.046 12.7 0.4 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain DndB PF14072.6 KFX94455.1 - 0.13 11.4 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 DNA-sulfur modification-associated Metallophos PF00149.28 KFX94456.1 - 1.1e-08 35.9 0.0 2.1e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX94456.1 - 2.6e-06 27.7 0.0 1.8e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Putative_PNPOx PF01243.20 KFX94457.1 - 0.00021 21.4 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Acyltransf_C PF16076.5 KFX94457.1 - 0.22 11.6 1.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Acyltransferase C-terminus PPR_2 PF13041.6 KFX94474.1 - 1.2e-48 163.1 3.5 3.4e-09 36.8 0.0 13.2 11 3 4 15 15 15 9 PPR repeat family PPR_3 PF13812.6 KFX94474.1 - 4.5e-35 119.5 0.0 0.0033 17.5 0.0 10.9 9 2 2 11 11 11 8 Pentatricopeptide repeat domain PPR PF01535.20 KFX94474.1 - 3.1e-25 86.6 17.4 0.00059 19.9 0.0 13.5 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.7 KFX94474.1 - 3.9e-23 80.8 0.7 1.1e-06 28.2 0.0 8.8 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KFX94474.1 - 7.6e-20 71.2 9.7 2.1e-08 33.8 0.0 5.1 4 1 0 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KFX94474.1 - 4.3e-05 23.9 0.1 0.0046 17.4 0.0 3.5 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 KFX94474.1 - 0.0079 16.7 1.9 4.2 8.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX94474.1 - 0.027 15.3 5.8 4.7 8.3 0.2 6.5 8 1 1 9 9 9 0 Tetratricopeptide repeat OSK PF17182.4 KFX94474.1 - 0.039 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 OSK domain zf-CCCH PF00642.24 KFX94480.1 - 0.00022 21.0 1.3 0.00022 21.0 1.3 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFX94480.1 - 0.0079 16.2 11.2 0.013 15.6 0.1 3.9 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 KFX94480.1 - 0.056 14.1 0.5 0.056 14.1 0.5 2.3 1 1 1 2 2 2 0 Torus domain Lustrin_cystein PF14625.6 KFX94480.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.5 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.6 KFX94480.1 - 0.43 11.1 12.6 1.1 9.9 0.2 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CDP-OH_P_transf PF01066.21 KFX94481.1 - 1.2e-11 45.3 0.5 1.2e-11 45.3 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KFX94481.1 - 0.052 13.0 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Thermopsin SRP19 PF01922.17 KFX94482.1 - 3.6e-32 111.2 0.0 5.5e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein HipN PF18253.1 KFX94482.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain Het-C PF07217.11 KFX94483.1 - 3.6e-274 910.5 0.0 4.3e-274 910.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.28 KFX94484.1 - 4.5e-18 65.2 1.5 8.8e-18 64.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KFX94484.1 - 6.4e-13 49.2 16.2 1.2e-12 48.3 16.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KFX94484.1 - 0.0034 17.6 0.1 0.015 15.5 0.1 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region LrgB PF04172.16 KFX94484.1 - 6.5 6.2 5.9 19 4.7 5.9 1.7 1 1 0 1 1 1 0 LrgB-like family Zn_clus PF00172.18 KFX94495.1 - 1.1e-06 28.7 9.7 1.8e-06 28.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 KFX94496.1 - 3.2e-38 131.6 0.0 3.9e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 Sugar_tr PF00083.24 KFX94498.1 - 1.8e-76 257.9 12.9 2e-76 257.7 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94498.1 - 5.8e-30 104.4 12.6 8.8e-30 103.8 12.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX94498.1 - 0.0009 17.8 0.3 0.0009 17.8 0.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX94498.1 - 0.043 12.1 2.1 0.1 10.8 0.3 2.3 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KFX94498.1 - 0.053 12.4 8.0 0.47 9.3 0.1 2.5 1 1 0 2 2 2 0 MFS_1 like family FAD_binding_3 PF01494.19 KFX94499.1 - 2.2e-14 53.5 0.0 1.2e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX94499.1 - 0.00022 20.6 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94499.1 - 0.00079 19.6 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX94499.1 - 0.022 14.0 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KFX94499.1 - 0.14 11.1 0.2 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein zf-CCHC PF00098.23 KFX94500.1 - 1.4e-10 40.7 5.8 1.1e-07 31.6 2.5 2.4 2 0 0 2 2 2 2 Zinc knuckle Rad51 PF08423.11 KFX94501.1 - 4.3e-107 357.1 0.0 5.6e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFX94501.1 - 1.5e-11 44.3 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFX94501.1 - 8.4e-06 25.3 0.0 2.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFX94501.1 - 9.5e-05 22.1 0.0 0.00023 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFX94501.1 - 0.0098 16.5 2.1 0.03 14.9 0.9 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KFX94501.1 - 0.015 14.7 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_pol_A_CTD PF03118.15 KFX94501.1 - 0.042 13.6 0.4 0.096 12.5 0.4 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PAXNEB PF05625.11 KFX94501.1 - 0.075 12.2 0.9 3.8 6.6 0.2 2.4 2 2 0 2 2 2 0 PAXNEB protein Ald_Xan_dh_C PF01315.22 KFX94501.1 - 0.17 12.3 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain RRP7 PF12923.7 KFX94502.1 - 8.1e-34 116.3 11.1 8.1e-34 116.3 11.1 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KFX94502.1 - 9.1e-22 77.6 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 KFX94502.1 - 0.078 13.3 0.0 0.078 13.3 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) CsbD PF05532.12 KFX94503.1 - 3.1e-15 55.8 28.6 1.8e-08 34.1 9.8 3.2 3 0 0 3 3 3 3 CsbD-like UPF0444 PF15475.6 KFX94503.1 - 0.2 11.9 0.5 0.2 11.9 0.5 2.6 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Aminotran_5 PF00266.19 KFX94504.1 - 2.6e-93 312.9 0.0 3.2e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX94504.1 - 2.2e-06 27.2 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFX94504.1 - 9.9e-05 21.8 0.1 0.00034 20.0 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFX94504.1 - 0.0064 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain G6PD_C PF02781.16 KFX94519.1 - 4.3e-115 383.9 0.0 1.1e-114 382.6 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFX94519.1 - 1.3e-62 211.5 0.2 2.4e-62 210.7 0.2 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 KFX94519.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) ArAE_1_C PF11728.8 KFX94519.1 - 0.016 15.2 0.4 0.034 14.1 0.4 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Ribosomal_L35Ae PF01247.18 KFX94524.1 - 4e-43 145.5 0.3 4.6e-43 145.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KFX94524.1 - 0.007 16.6 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain VMA21 PF09446.10 KFX94525.1 - 1.9e-14 53.5 11.6 3.4e-14 52.7 11.6 1.4 1 0 0 1 1 1 1 VMA21-like domain Ank_2 PF12796.7 KFX94529.1 - 1.9e-58 195.0 19.5 1.6e-16 60.6 1.9 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFX94529.1 - 1.9e-36 122.9 15.1 8.8e-06 25.9 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFX94529.1 - 6.9e-36 118.2 9.8 3.3e-05 23.9 0.1 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KFX94529.1 - 6.7e-33 112.7 7.4 1.3e-09 38.3 0.2 6.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX94529.1 - 1.4e-28 98.5 10.2 2.2e-06 27.8 0.0 6.8 2 2 5 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 KFX94529.1 - 9.5e-08 32.1 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFX94529.1 - 1.8e-06 28.3 0.2 1.7e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain Helo_like_N PF17111.5 KFX94529.1 - 0.0041 16.5 1.4 0.0078 15.6 0.0 2.2 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KFX94529.1 - 0.0091 16.4 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF913 PF06025.12 KFX94529.1 - 0.12 11.3 0.0 0.28 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_S6 PF01250.17 KFX94529.1 - 0.17 12.2 0.1 15 5.9 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein S6 Thiolase_N PF00108.23 KFX94534.1 - 8.2e-73 244.9 0.7 8.2e-73 244.9 0.7 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX94534.1 - 2.6e-41 140.1 1.0 5.9e-41 139.0 1.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX94534.1 - 0.036 13.6 1.6 0.23 11.0 0.4 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Zn_clus PF00172.18 KFX94550.1 - 1.4e-07 31.5 13.6 2.1e-07 31.0 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RskA PF10099.9 KFX94550.1 - 0.036 14.4 5.0 0.037 14.3 4.9 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA VCX_VCY PF15231.6 KFX94550.1 - 8.2 7.1 12.6 9.3 6.9 11.7 1.4 1 1 0 1 1 1 0 Variable charge X/Y family E1-E2_ATPase PF00122.20 KFX94551.1 - 7.1e-40 136.4 6.9 1.8e-39 135.2 6.9 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFX94551.1 - 9e-27 94.7 0.0 1.5e-26 94.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFX94551.1 - 1.5e-08 34.9 0.2 1.5e-07 31.7 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFX94551.1 - 0.00024 20.9 0.6 0.026 14.3 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX94551.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFX94551.1 - 0.025 14.6 0.1 0.11 12.5 0.1 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 KFX94553.1 - 7.5e-26 91.5 15.6 1.4e-25 90.6 15.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFX94553.1 - 0.0042 17.3 0.0 0.037 14.2 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) FAP PF07174.11 KFX94554.1 - 0.61 9.5 8.9 0.72 9.3 8.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2403 PF10290.9 KFX94569.1 - 4.9e-27 94.1 0.0 7.6e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RhoGAP PF00620.27 KFX94572.1 - 1.1e-41 142.2 0.0 2.2e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain JIP_LZII PF16471.5 KFX94572.1 - 1.4 9.2 7.7 0.11 12.7 2.0 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Nucleoporin_N PF08801.11 KFX94573.1 - 4.6e-98 328.8 0.2 6.6e-98 328.3 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 KFX94573.1 - 1.3e-68 231.2 0.0 3.1e-68 230.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Nucleoporin_C PF03177.14 KFX94573.1 - 5.2e-52 177.4 0.4 4e-51 174.5 0.5 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Pkinase_Tyr PF07714.17 KFX94573.1 - 4.3e-33 114.7 0.0 7.8e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFX94573.1 - 2.1e-09 37.9 0.3 5.8e-09 36.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFX94573.1 - 1.8e-05 23.9 0.0 1.8e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KFX94573.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3802 PF12290.8 KFX94573.1 - 0.04 14.4 0.4 0.16 12.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) C2 PF00168.30 KFX94573.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain Peptidase_M41 PF01434.18 KFX94591.1 - 8.6e-61 205.1 3.5 2e-59 200.7 2.9 2.3 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KFX94591.1 - 6.9e-42 143.0 0.0 1.9e-41 141.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX94591.1 - 3.7e-12 45.8 0.0 7.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX94591.1 - 1.2e-05 25.7 0.1 0.00026 21.4 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFX94591.1 - 2.7e-05 23.6 0.0 6.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFX94591.1 - 5.8e-05 23.1 0.0 0.00021 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX94591.1 - 0.00021 21.6 0.0 0.069 13.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KFX94591.1 - 0.00075 19.3 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFX94591.1 - 0.0028 17.8 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KFX94591.1 - 0.012 15.4 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX94591.1 - 0.019 14.5 0.2 0.46 10.0 0.1 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFX94591.1 - 0.025 14.0 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFX94591.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KFX94591.1 - 0.054 13.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFX94591.1 - 0.055 13.0 0.7 0.8 9.2 0.4 2.5 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KFX94591.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KFX94591.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KFX94591.1 - 0.16 11.2 1.2 0.7 9.1 0.4 2.2 1 1 1 2 2 2 0 Zeta toxin zf-C2H2 PF00096.26 KFX94592.1 - 1.5e-18 66.2 28.9 3.8e-05 23.9 0.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX94592.1 - 1.1e-17 63.6 26.8 1.2e-06 28.6 0.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX94592.1 - 1.9e-08 34.5 27.0 0.016 16.0 1.1 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX94592.1 - 0.0028 17.9 9.8 0.87 10.0 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFX94592.1 - 0.01 15.6 1.5 0.01 15.6 1.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFX94592.1 - 0.026 14.8 9.7 1.2 9.5 6.7 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFX94592.1 - 0.047 14.3 1.3 0.047 14.3 1.3 4.9 5 1 2 7 7 7 0 FOXP coiled-coil domain Hexokinase_1 PF00349.21 KFX94601.1 - 3e-76 255.8 0.0 4.4e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KFX94601.1 - 2.8e-73 246.3 0.2 3.9e-73 245.8 0.2 1.2 1 0 0 1 1 1 1 Hexokinase Peptidase_A22B PF04258.13 KFX94603.1 - 2.4e-58 197.9 0.6 4.9e-58 196.9 0.6 1.4 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFX94603.1 - 0.0063 16.0 14.4 0.0075 15.8 3.4 3.0 2 1 1 3 3 3 2 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFX94603.1 - 1.5 7.5 6.6 0.75 8.5 0.4 2.9 2 1 1 3 3 3 0 Presenilin Pro_isomerase PF00160.21 KFX94604.1 - 3.3e-51 173.7 0.0 3.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetyltransf_1 PF00583.25 KFX94605.1 - 0.021 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family STI1 PF17830.1 KFX94612.1 - 5.6e-05 23.0 11.7 0.0021 18.0 8.2 2.1 2 0 0 2 2 2 2 STI1 domain XPC-binding PF09280.11 KFX94612.1 - 0.0079 15.9 4.2 0.025 14.3 1.9 2.3 2 1 0 2 2 2 1 XPC-binding domain GerD PF17898.1 KFX94612.1 - 0.057 13.4 2.0 0.63 10.0 1.1 2.0 2 0 0 2 2 2 0 Spore germination GerD central core domain ABC_tran PF00005.27 KFX94613.1 - 6.3e-34 117.4 0.1 1.7e-33 116.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KFX94613.1 - 4.7e-25 88.8 1.8 1e-24 87.6 1.8 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFX94613.1 - 1.4e-06 27.9 0.0 0.00014 21.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFX94613.1 - 0.00025 20.9 0.1 0.00041 20.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 KFX94613.1 - 0.0006 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFX94613.1 - 0.0025 17.7 0.3 0.0065 16.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX94613.1 - 0.0032 17.8 0.2 0.022 15.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFX94613.1 - 0.0038 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX94613.1 - 0.0048 16.7 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zeta_toxin PF06414.12 KFX94613.1 - 0.0057 15.9 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KFX94613.1 - 0.0079 15.9 0.2 0.024 14.3 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX94613.1 - 0.0082 16.1 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KFX94613.1 - 0.0099 15.6 0.4 0.1 12.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KFX94613.1 - 0.015 15.8 0.6 0.037 14.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KFX94613.1 - 0.027 14.5 0.0 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KFX94613.1 - 0.027 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 KFX94613.1 - 0.029 14.9 0.4 1.2 9.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Polysacc_synt_C PF14667.6 KFX94613.1 - 1.1 9.3 16.7 0.087 12.9 3.9 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain YchF-GTPase_C PF06071.13 KFX94615.1 - 1.5e-34 118.0 0.5 3.9e-34 116.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFX94615.1 - 1.4e-16 60.6 0.0 5.8e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX94615.1 - 0.00061 19.4 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 KFX94615.1 - 0.0007 19.6 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain AAA_21 PF13304.6 KFX94615.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX94615.1 - 3.1 8.3 6.7 54 4.2 6.3 2.6 1 1 0 1 1 1 0 AAA domain Alg14 PF08660.11 KFX94619.1 - 0.00056 19.9 0.0 0.00059 19.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Pkinase PF00069.25 KFX94622.1 - 7.9e-66 222.1 0.0 1.3e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94622.1 - 2.2e-51 174.6 0.0 4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KFX94622.1 - 2.8e-29 101.4 0.0 5.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KFX94622.1 - 6.1e-16 58.6 0.2 1.3e-15 57.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFX94622.1 - 2.6e-13 49.8 0.1 5.2e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFX94622.1 - 1.1e-09 38.8 0.1 2.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KFX94622.1 - 2.3e-08 33.7 0.0 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.16 KFX94622.1 - 0.0012 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 KFX94622.1 - 0.07 11.9 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SAM_4 PF18017.1 KFX94622.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MBOAT PF03062.19 KFX94623.1 - 3.1e-48 164.9 7.5 3.1e-48 164.9 7.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.23 KFX94624.1 - 1.7e-133 446.9 0.9 1.9e-133 446.7 0.9 1.0 1 0 0 1 1 1 1 Sec1 family HEAT_2 PF13646.6 KFX94624.1 - 0.056 13.8 0.2 1.7 9.1 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats GARS_A PF01071.19 KFX94625.1 - 2.6e-85 285.1 0.3 3.2e-84 281.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KFX94625.1 - 2.9e-35 121.7 0.1 6.8e-35 120.5 0.1 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KFX94625.1 - 8.6e-35 119.4 0.1 4.2e-34 117.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KFX94625.1 - 4e-25 87.9 0.3 1.7e-24 85.9 0.3 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KFX94625.1 - 1.9e-14 54.1 4.0 5.8e-14 52.5 2.8 2.5 2 1 1 3 3 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 KFX94625.1 - 3.4e-05 23.5 0.0 8.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KFX94625.1 - 4.1e-05 23.2 0.1 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KFX94625.1 - 0.00047 19.8 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFX94625.1 - 0.00095 19.2 0.0 0.0033 17.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KFX94625.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KFX94625.1 - 0.1 11.8 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 KFX94625.1 - 0.1 12.1 0.1 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Tetraspanin PF00335.20 KFX94628.1 - 0.0093 15.7 0.6 0.011 15.5 0.6 1.0 1 0 0 1 1 1 1 Tetraspanin family MRVI1 PF05781.12 KFX94628.1 - 0.26 9.9 0.0 0.31 9.7 0.0 1.0 1 0 0 1 1 1 0 MRVI1 protein O-FucT PF10250.9 KFX94629.1 - 3.2e-14 53.4 0.0 1.6e-12 47.8 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Tannase PF07519.11 KFX94631.1 - 3.4e-116 388.9 2.6 4.3e-116 388.6 2.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase ADP_PFK_GK PF04587.15 KFX94633.1 - 0.06 11.9 0.0 0.073 11.6 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RNase_H PF00075.24 KFX94635.1 - 4.9e-14 52.7 0.0 6.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 RNase H BNR_2 PF13088.6 KFX94637.1 - 9.2e-22 77.6 0.3 1.1e-20 74.1 0.3 2.0 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFX94637.1 - 2.5e-07 29.7 22.7 0.068 13.2 0.5 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.6 KFX94637.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain CHB_HEX_C PF03174.13 KFX94637.1 - 0.0056 16.6 0.8 9.9 6.2 0.0 4.1 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 KFX94637.1 - 0.38 9.5 10.3 3 6.6 0.1 3.6 2 2 1 4 4 4 0 Sortilin, neurotensin receptor 3, Mis14 PF08641.12 KFX94649.1 - 3.3e-11 43.6 0.2 3.3e-11 43.6 0.2 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like SWI-SNF_Ssr4 PF08549.10 KFX94650.1 - 0.0046 15.7 2.3 0.011 14.4 2.3 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) ORC6 PF05460.13 KFX94650.1 - 0.039 13.2 0.5 0.034 13.4 0.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) APC_basic PF05956.11 KFX94650.1 - 0.042 13.3 12.1 0.052 13.0 12.1 1.1 1 0 0 1 1 1 0 APC basic domain AAA PF00004.29 KFX94651.1 - 2e-45 154.4 0.7 6.8e-45 152.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX94651.1 - 1.3e-10 41.0 0.1 7.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFX94651.1 - 6.8e-09 35.8 0.5 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX94651.1 - 4.6e-08 33.4 0.0 9.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFX94651.1 - 1.5e-07 32.0 0.5 3.4e-05 24.3 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFX94651.1 - 3.5e-06 26.4 0.0 6.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFX94651.1 - 3.9e-05 23.9 1.2 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFX94651.1 - 0.0002 21.1 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFX94651.1 - 0.00038 20.5 0.0 0.028 14.4 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFX94651.1 - 0.00046 20.7 0.0 0.0013 19.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 KFX94651.1 - 0.00058 19.6 0.1 0.0013 18.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 KFX94651.1 - 0.00061 19.3 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KFX94651.1 - 0.00071 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFX94651.1 - 0.0014 18.7 0.1 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX94651.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KFX94651.1 - 0.004 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KFX94651.1 - 0.0043 16.8 0.1 0.012 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFX94651.1 - 0.0051 16.1 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KFX94651.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX94651.1 - 0.008 16.1 0.7 0.11 12.4 0.0 2.8 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KFX94651.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFX94651.1 - 0.0089 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFX94651.1 - 0.0094 15.7 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 KFX94651.1 - 0.011 15.2 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KFX94651.1 - 0.024 14.4 0.2 0.056 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFX94651.1 - 0.034 14.1 1.0 0.26 11.2 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KFX94651.1 - 0.038 13.4 0.9 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KFX94651.1 - 0.038 13.8 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KFX94651.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KFX94651.1 - 0.079 12.7 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 KFX94651.1 - 0.079 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AFG1_ATPase PF03969.16 KFX94651.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFX94651.1 - 0.091 12.0 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_23 PF13476.6 KFX94651.1 - 0.097 13.2 0.3 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFX94651.1 - 0.12 12.7 0.1 0.38 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFX94651.1 - 0.12 11.9 1.6 0.27 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 KFX94651.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFX94651.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KFX94651.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SHMT PF00464.19 KFX94652.1 - 1.1e-206 686.1 0.0 1.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KFX94652.1 - 8.7e-05 21.8 0.0 0.00019 20.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX94652.1 - 0.00081 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX94652.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFX94652.1 - 0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Baculo_DNA_bind PF04786.12 KFX94652.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein Nop PF01798.18 KFX94653.1 - 1.3e-88 296.4 0.1 2.1e-88 295.7 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFX94653.1 - 4.6e-19 68.6 0.5 4.2e-18 65.5 0.0 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KFX94653.1 - 3 7.9 22.7 6.3 6.8 22.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KFX94653.1 - 5.5 6.7 11.8 10 5.8 11.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA PF00004.29 KFX94654.1 - 6.5e-43 146.3 0.1 1.5e-42 145.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFX94654.1 - 6e-30 103.0 0.1 2e-29 101.3 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KFX94654.1 - 1.8e-23 82.3 4.5 4.1e-23 81.2 4.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_2 PF07724.14 KFX94654.1 - 4.9e-06 26.8 0.5 0.0031 17.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFX94654.1 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KFX94654.1 - 1.7e-05 24.5 0.0 0.00021 21.1 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 KFX94654.1 - 2.6e-05 24.2 0.0 7.8e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFX94654.1 - 6.9e-05 22.6 0.0 0.00019 21.2 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFX94654.1 - 8.7e-05 23.0 0.1 0.009 16.4 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 KFX94654.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain USP8_dimer PF08969.11 KFX94654.1 - 0.0003 21.0 2.7 0.00063 19.9 2.7 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_22 PF13401.6 KFX94654.1 - 0.0003 21.1 0.1 0.08 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KFX94654.1 - 0.00042 20.5 0.0 0.0014 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX94654.1 - 0.001 18.3 0.0 0.0033 16.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 KFX94654.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX94654.1 - 0.0016 18.8 0.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KFX94654.1 - 0.0059 16.2 0.2 0.68 9.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX94654.1 - 0.0068 15.9 0.1 0.13 11.8 0.0 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_17 PF13207.6 KFX94654.1 - 0.0071 16.8 0.7 0.017 15.5 0.0 2.2 2 1 1 3 3 1 1 AAA domain Mg_chelatase PF01078.21 KFX94654.1 - 0.0093 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFX94654.1 - 0.0096 16.5 0.1 0.034 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX94654.1 - 0.03 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFX94654.1 - 0.075 12.7 0.0 0.44 10.2 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 KFX94654.1 - 0.098 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 KFX94654.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KFX94654.1 - 0.13 11.5 0.1 1.9 7.7 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin ATPase PF06745.13 KFX94654.1 - 0.16 11.3 0.1 8.3 5.7 0.0 2.4 1 1 1 2 2 2 0 KaiC ATPase_2 PF01637.18 KFX94654.1 - 0.2 11.6 0.9 2.4 8.0 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea MutS_V PF00488.21 KFX94658.1 - 2.5e-66 223.3 0.2 4.3e-66 222.5 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX94658.1 - 8.6e-40 137.0 0.0 1.8e-39 135.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFX94658.1 - 2.3e-32 111.6 0.3 7.2e-32 110.0 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KFX94658.1 - 4e-15 55.9 0.0 8.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KFX94658.1 - 2.9e-12 47.0 0.0 7.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 KFX94658.1 - 0.00044 20.8 0.1 0.0012 19.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KFX94658.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX94658.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFX94658.1 - 0.21 11.4 2.9 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PSRT PF07636.11 KFX94658.1 - 0.39 10.4 9.2 1.6 8.5 9.2 2.0 1 0 0 1 1 1 0 PSRT polyprenyl_synt PF00348.17 KFX94672.1 - 4.5e-92 307.7 0.0 6.4e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase ANAPC8 PF04049.13 KFX94673.1 - 6e-58 194.9 0.9 2.7e-57 192.7 0.2 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 DUF5353 PF17304.2 KFX94675.1 - 6e-36 122.0 3.0 9.9e-36 121.3 3.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF883 PF05957.13 KFX94675.1 - 0.0093 16.5 1.9 0.0093 16.5 1.9 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) ETRAMP PF09716.10 KFX94675.1 - 0.01 15.9 1.7 0.014 15.4 1.7 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RAP1 PF07218.11 KFX94675.1 - 0.011 14.1 0.7 0.012 14.0 0.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4337 PF14235.6 KFX94675.1 - 0.019 15.1 0.6 0.035 14.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HSP70 PF00012.20 KFX94675.1 - 0.21 9.8 4.4 0.27 9.4 4.4 1.1 1 0 0 1 1 1 0 Hsp70 protein V-SNARE_C PF12352.8 KFX94676.1 - 1.5e-14 54.0 0.1 3.2e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFX94676.1 - 0.00013 21.8 0.4 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 Sec20 KxDL PF10241.9 KFX94676.1 - 0.079 13.2 3.8 2.8 8.3 1.2 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 KFX94676.1 - 0.091 12.8 1.9 0.25 11.4 1.5 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 KFX94676.1 - 0.095 13.1 0.2 0.95 9.9 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin TPR_MLP1_2 PF07926.12 KFX94676.1 - 2.3 8.3 7.3 0.96 9.5 3.0 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPK_catalytic PF04263.16 KFX94677.1 - 2.7e-26 92.0 0.0 3.6e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KFX94677.1 - 6e-22 77.1 0.0 1.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain E1-E2_ATPase PF00122.20 KFX94678.1 - 5e-18 65.3 0.0 1.1e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFX94678.1 - 2.8e-13 50.6 5.1 7.7e-08 32.9 1.7 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX94678.1 - 9.2e-05 22.5 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFX94678.1 - 0.0038 17.0 0.2 0.041 13.6 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4376 PF14301.6 KFX94678.1 - 7.2 7.0 7.2 0.73 10.2 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) DUF4139 PF13598.6 KFX94679.1 - 2.6e-15 56.7 0.0 1.6e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) CHCH PF06747.13 KFX94681.1 - 9.7e-10 38.3 11.5 2.8e-08 33.7 2.2 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KFX94681.1 - 6.7e-06 26.0 4.9 0.00041 20.3 1.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TF_Otx PF03529.13 KFX94681.1 - 0.13 12.7 1.0 0.22 12.0 1.0 1.4 1 0 0 1 1 1 0 Otx1 transcription factor Cmc1 PF08583.10 KFX94681.1 - 0.48 10.5 10.6 3.8 7.6 2.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KFX94681.1 - 3.5 7.9 10.2 11 6.4 2.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 KFX94681.1 - 8.6 6.7 7.5 62 3.9 5.8 2.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein zf-H2C2 PF09337.10 KFX94687.1 - 2.3e-15 56.5 0.6 6e-15 55.2 0.6 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KFX94687.1 - 9.6e-12 44.8 0.4 2e-11 43.8 0.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KFX94687.1 - 0.00028 21.1 0.0 0.00061 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KFX94687.1 - 0.022 15.4 0.2 0.089 13.5 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX94687.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KFX94687.1 - 0.05 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RINT1_TIP1 PF04437.13 KFX94688.1 - 2.9e-165 551.0 0.3 6.7e-165 549.7 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Herpes_U30 PF04523.13 KFX94688.1 - 0.013 13.5 0.8 0.019 12.9 0.8 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Fez1 PF06818.15 KFX94688.1 - 0.049 14.1 1.2 0.1 13.1 1.2 1.5 1 0 0 1 1 1 0 Fez1 Sec34 PF04136.15 KFX94688.1 - 0.054 13.4 1.7 0.24 11.3 1.5 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4164 PF13747.6 KFX94688.1 - 0.38 11.1 5.4 2.6 8.4 3.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DNA_ligase_A_M PF01068.21 KFX94689.1 - 4.4e-51 173.4 0.0 2.6e-48 164.4 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFX94689.1 - 1.5e-35 123.1 0.0 2.8e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFX94689.1 - 1.5e-17 64.0 0.0 6.7e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFX94689.1 - 5.3e-05 23.6 0.0 0.00012 22.4 0.0 1.6 2 0 0 2 2 2 1 RNA ligase Sugar_tr PF00083.24 KFX94690.1 - 2.1e-41 142.2 26.7 6.3e-39 134.1 26.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94690.1 - 2.5e-27 95.7 31.8 1.7e-13 50.3 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KFX94690.1 - 0.047 13.4 1.6 0.086 12.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PhyH PF05721.13 KFX94691.1 - 1.2e-25 91.0 0.0 1.6e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFX94691.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KFX94691.1 - 0.0023 18.8 0.0 0.0056 17.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glucosamine_iso PF01182.20 KFX94694.1 - 6.8e-23 81.7 0.0 1.1e-22 81.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC2_membrane PF01061.24 KFX94695.1 - 5.9e-79 264.4 59.2 1.4e-42 145.5 18.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX94695.1 - 3.1e-35 121.7 0.0 1.1e-17 64.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX94695.1 - 8.5e-28 96.1 7.4 3e-23 81.5 0.0 4.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX94695.1 - 2e-12 47.5 0.1 6.7e-12 45.9 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KFX94695.1 - 4.5e-07 29.3 36.7 1.7e-05 24.1 17.4 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KFX94695.1 - 6.4e-06 26.4 0.1 0.0041 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFX94695.1 - 8e-06 25.9 0.0 0.21 11.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFX94695.1 - 5.8e-05 23.7 0.0 0.0052 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX94695.1 - 6e-05 23.5 0.1 0.0061 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 KFX94695.1 - 0.00028 21.3 0.1 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX94695.1 - 0.0003 20.4 0.2 0.0087 15.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX94695.1 - 0.00032 20.4 2.4 0.013 15.2 0.2 3.6 5 0 0 5 5 4 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX94695.1 - 0.00063 19.7 0.2 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFX94695.1 - 0.0079 15.6 0.0 0.85 9.0 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KFX94695.1 - 0.0099 16.1 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX94695.1 - 0.014 15.2 0.1 2 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFX94695.1 - 0.025 14.3 0.1 12 5.6 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFX94695.1 - 0.027 14.4 0.3 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KFX94695.1 - 0.031 14.6 0.1 0.9 9.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KFX94695.1 - 0.071 12.7 1.6 0.5 9.9 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFX94695.1 - 0.19 12.1 0.2 26 5.2 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3 PF00933.21 KFX94696.1 - 1.7e-64 218.2 0.0 2.2e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_10 PF13673.7 KFX94696.1 - 0.00054 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 KFX94696.1 - 0.0031 17.5 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 KFX94696.1 - 0.0049 17.1 0.0 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX94696.1 - 0.13 12.7 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.12 KFX94697.1 - 1.8e-31 109.8 0.0 2.8e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Amidohydro_1 PF01979.20 KFX94698.1 - 6.7e-11 42.1 0.0 3.5e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX94698.1 - 7.1e-09 35.7 1.2 1.7e-07 31.1 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Abhydrolase_6 PF12697.7 KFX94699.1 - 4.3e-07 30.7 0.4 6.5e-07 30.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family T5orf172 PF10544.9 KFX94700.1 - 3.9e-11 43.4 0.7 8e-11 42.4 0.7 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KFX94700.1 - 1.6e-08 35.1 1.9 2.2e-08 34.7 0.8 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 DUF2457 PF10446.9 KFX94700.1 - 0.021 14.0 11.2 0.033 13.3 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KFX94700.1 - 0.24 10.7 11.4 0.36 10.1 11.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KFX94700.1 - 0.77 7.9 12.6 1 7.5 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFX94700.1 - 1.6 8.1 13.4 2.9 7.2 13.4 1.4 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 KFX94700.1 - 2.7 8.3 16.1 0.35 11.1 11.2 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DAO PF01266.24 KFX94703.1 - 1.4e-59 202.4 0.5 2.8e-59 201.5 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 KFX94703.1 - 6.4e-22 77.8 0.6 2.7e-21 75.8 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain Cellulase PF00150.18 KFX94703.1 - 4.1e-16 59.2 2.0 8.9e-16 58.1 2.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BBE PF08031.12 KFX94703.1 - 9.9e-12 44.8 0.0 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 KFX94703.1 - 6.5e-05 22.3 0.0 0.047 12.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX94703.1 - 0.0007 20.1 0.0 0.061 13.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_42 PF02449.15 KFX94703.1 - 0.0014 18.1 0.0 0.0041 16.5 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Mqo PF06039.15 KFX94703.1 - 0.0023 16.5 0.1 0.089 11.3 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KFX94703.1 - 0.0057 16.9 0.1 0.0057 16.9 0.1 3.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX94703.1 - 0.0068 15.5 0.9 0.017 14.2 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_2_C PF02836.17 KFX94703.1 - 0.009 15.2 0.0 0.027 13.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain GMC_oxred_N PF00732.19 KFX94703.1 - 0.062 12.7 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.17 KFX94703.1 - 0.18 11.0 0.3 0.66 9.2 0.2 1.9 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 KFX94703.1 - 0.84 8.3 7.1 0.075 11.8 0.3 2.4 3 0 0 3 3 3 0 MCRA family tRNA-synt_2d PF01409.20 KFX94707.1 - 1.3e-46 159.1 1.1 4.1e-24 85.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GrpE PF01025.19 KFX94707.1 - 4.2e-42 143.6 4.4 7.4e-42 142.8 4.4 1.4 1 0 0 1 1 1 1 GrpE FDX-ACB PF03147.14 KFX94707.1 - 1.2e-26 93.0 0.1 3.3e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Tai4 PF16695.5 KFX94707.1 - 0.16 12.5 1.1 0.41 11.2 1.1 1.7 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein Mito_carr PF00153.27 KFX94708.1 - 2.4e-59 197.3 1.1 3.1e-21 75.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.26 KFX94709.1 - 2.9e-32 111.3 0.0 5.2e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFX94709.1 - 1.3e-18 66.1 0.0 1.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.12 KFX94710.1 - 8.1e-50 169.1 0.2 9.9e-50 168.9 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Mob1_phocein PF03637.17 KFX94711.1 - 1.4e-71 239.9 0.0 2.9e-71 238.9 0.0 1.5 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 KFX94711.1 - 9.4e-47 159.3 2.3 1.5e-46 158.7 2.3 1.3 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.17 KFX94711.1 - 0.032 14.3 0.3 0.081 13.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Rgp1 PF08737.10 KFX94712.1 - 3.4e-162 540.4 0.0 5.4e-162 539.7 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KFX94712.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain CRM1_C PF08767.11 KFX94713.1 - 1.3e-133 445.1 1.5 1.1e-132 442.1 0.3 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KFX94713.1 - 9.2e-38 129.6 8.0 1.6e-37 128.8 3.6 3.6 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFX94713.1 - 3.9e-34 116.1 4.2 1.3e-33 114.5 4.2 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFX94713.1 - 3.5e-29 100.7 2.5 8.9e-29 99.4 1.2 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFX94713.1 - 2.6e-20 71.6 1.3 7.2e-20 70.2 1.3 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFX94713.1 - 8.3e-13 48.1 0.1 3.4e-12 46.1 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KFX94713.1 - 0.0068 16.3 14.1 0.24 11.3 0.2 4.7 4 2 1 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal HD_assoc PF13286.6 KFX94713.1 - 0.024 15.1 0.2 23 5.6 0.2 3.5 3 0 0 3 3 2 0 Phosphohydrolase-associated domain DUF3385 PF11865.8 KFX94713.1 - 0.058 13.3 6.2 0.21 11.5 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 KFX94713.1 - 0.4 11.3 1.9 2.6 8.7 0.0 3.4 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region Prolamin_like PF05617.11 KFX94713.1 - 1.2 9.3 3.5 12 6.2 0.0 3.6 4 0 0 4 4 4 0 Prolamin-like Reprolysin_5 PF13688.6 KFX94714.1 - 2.3e-58 197.6 7.1 2.3e-58 197.6 7.1 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFX94714.1 - 3.6e-50 170.6 3.9 6.4e-50 169.8 3.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KFX94714.1 - 7.7e-44 149.8 3.0 1.5e-43 148.8 3.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KFX94714.1 - 1.5e-15 57.8 30.7 1.5e-15 57.8 30.7 4.3 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KFX94714.1 - 8.6e-11 42.4 0.1 1.9e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 KFX94714.1 - 1.8e-05 25.1 14.7 1.8e-05 25.1 14.7 5.7 2 1 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 KFX94714.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide G_glu_transpept PF01019.21 KFX94715.1 - 1.3e-163 545.4 0.4 1.6e-163 545.2 0.4 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase IMS PF00817.20 KFX94716.1 - 1.2e-39 135.7 0.0 1.8e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFX94716.1 - 3.8e-17 63.1 0.2 5.1e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFX94716.1 - 0.0063 16.8 0.0 0.027 14.8 0.0 2.2 1 0 0 1 1 1 1 IMS family HHH motif HHH_8 PF14716.6 KFX94716.1 - 0.11 12.8 0.0 0.46 10.9 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain SCNM1_acidic PF15805.5 KFX94717.1 - 0.084 12.6 0.7 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Ribosomal_L3 PF00297.22 KFX94718.1 - 1.1e-185 616.9 11.9 1.3e-185 616.7 11.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PWI PF01480.17 KFX94720.1 - 2.5e-31 107.8 0.0 3.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 PWI domain GRP PF07172.11 KFX94720.1 - 0.09 13.5 1.5 0.15 12.7 1.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family DEAD PF00270.29 KFX94722.1 - 5.3e-21 75.2 0.0 1.1e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX94722.1 - 1.6e-18 67.0 0.0 4.2e-17 62.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 KFX94722.1 - 5.4e-17 61.6 0.2 1.1e-16 60.6 0.2 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 KFX94722.1 - 1.4e-16 61.0 6.5 5.2e-16 59.1 6.5 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFX94722.1 - 0.0001 22.4 0.0 0.00033 20.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KFX94722.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 HRDC domain Collar PF07484.12 KFX94723.1 - 0.098 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Collar Domain APH PF01636.23 KFX94724.1 - 0.00061 19.8 0.2 0.0017 18.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 KFX94725.1 - 3.4e-10 40.0 0.1 2.2e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX94725.1 - 3.2e-07 31.2 0.1 4.3e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3846 PF12957.7 KFX94725.1 - 0.0025 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) DUF1509 PF07420.11 KFX94727.1 - 0.088 11.8 2.3 0.13 11.2 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) Glyco_tranf_2_3 PF13641.6 KFX94728.1 - 1.4e-18 67.6 0.0 1.8e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX94728.1 - 6.1e-07 29.4 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFX94728.1 - 5.5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Abhydrolase_1 PF00561.20 KFX94729.1 - 9.4e-15 54.9 0.2 2.4e-14 53.6 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX94729.1 - 4e-10 40.7 3.3 5.4e-10 40.3 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX94729.1 - 2.5e-08 33.5 0.0 4.2e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KFX94729.1 - 0.0054 16.3 0.1 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 KFX94729.1 - 0.0061 16.2 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KFX94729.1 - 0.056 13.3 0.0 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 KFX94729.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.13 KFX94729.1 - 0.18 11.4 0.0 0.74 9.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 KFX94729.1 - 0.2 10.9 0.0 0.51 9.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans_2 PF11951.8 KFX94730.1 - 3.5e-16 59.0 0.3 6.4e-16 58.1 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Drf_FH1 PF06346.12 KFX94730.1 - 0.033 13.9 2.6 0.06 13.1 2.6 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 Sugar_tr PF00083.24 KFX94731.1 - 1.8e-73 248.0 14.0 2.1e-44 152.2 1.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX94731.1 - 1.9e-15 56.7 22.9 2.3e-15 56.4 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX94731.1 - 0.0001 21.0 0.1 0.0001 21.0 0.1 3.4 3 1 0 4 4 4 1 MFS/sugar transport protein PUCC PF03209.15 KFX94731.1 - 0.0014 17.7 0.2 0.0031 16.6 0.2 1.5 1 0 0 1 1 1 1 PUCC protein Ank_2 PF12796.7 KFX94732.1 - 4.1e-25 88.2 1.3 2.1e-12 47.5 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFX94732.1 - 3.4e-22 77.8 9.5 2.1e-05 24.8 0.3 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFX94732.1 - 2e-18 64.6 3.3 0.0016 18.7 0.1 6.0 6 0 0 6 6 5 4 Ankyrin repeat Ank_4 PF13637.6 KFX94732.1 - 2.4e-17 63.1 8.1 4.3e-07 30.3 0.4 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX94732.1 - 1.7e-14 53.7 9.9 3.5e-05 24.0 0.4 5.5 2 1 2 5 5 5 4 Ankyrin repeats (many copies) TPR_8 PF13181.6 KFX94732.1 - 0.00084 19.4 0.7 0.00084 19.4 0.7 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX94732.1 - 0.0027 18.0 0.9 0.0067 16.7 0.3 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX94732.1 - 0.0048 16.3 0.5 0.01 15.2 0.1 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KFX94732.1 - 0.016 15.2 3.1 0.034 14.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX94732.1 - 0.036 14.9 0.9 0.44 11.5 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX94732.1 - 0.15 11.9 1.8 0.4 10.6 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX94732.1 - 0.24 12.0 1.2 1.7 9.2 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFX94733.1 - 2.4e-42 145.1 69.3 4.1e-39 134.5 58.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily IQCJ-SCHIP1 PF15157.6 KFX94733.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Amino_oxidase PF01593.24 KFX94735.1 - 4.1e-30 105.5 0.0 5.6e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX94735.1 - 4.7e-10 39.6 0.2 1.1e-09 38.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX94735.1 - 8.7e-05 22.3 0.0 0.00095 18.8 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX94735.1 - 0.00091 18.7 0.3 0.0017 17.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX94735.1 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX94735.1 - 0.041 13.1 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KFX94735.1 - 0.072 13.7 1.2 1.7 9.2 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX94735.1 - 0.096 11.4 0.8 0.14 10.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX94735.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KFX94735.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PGF-CTERM PF18204.1 KFX94735.1 - 0.85 9.7 2.8 2.2 8.4 0.3 2.4 2 0 0 2 2 2 0 PGF-CTERM motif PUF PF00806.19 KFX94742.1 - 2e-31 105.9 8.1 2e-08 33.5 0.1 4.8 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Catalase PF00199.19 KFX94744.1 - 8.7e-25 87.6 0.2 1.2e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFX94744.1 - 5.1e-11 42.6 0.0 8.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive 2H-phosphodiest PF08975.10 KFX94745.1 - 2.3e-12 46.9 0.0 2.5e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.16 KFX94745.1 - 0.00024 21.2 0.1 0.00063 19.9 0.0 1.7 2 0 0 2 2 2 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KFX94745.1 - 0.0019 18.1 0.1 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily HVSL PF09749.9 KFX94745.1 - 0.11 12.0 0.0 0.8 9.1 0.0 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein DUF3659 PF12396.8 KFX94747.1 - 4.1e-112 366.1 67.3 7.7e-23 80.2 7.6 6.5 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) CorA PF01544.18 KFX94747.1 - 0.14 11.5 0.0 0.38 10.0 0.4 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PMC2NT PF08066.12 KFX94747.1 - 0.36 11.6 1.9 2.2 9.0 0.1 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF1993 PF09351.10 KFX94747.1 - 1 9.5 4.7 0.75 9.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Pes-10 PF07149.11 KFX94748.1 - 5.7 5.9 8.1 9.2 5.2 8.1 1.3 1 0 0 1 1 1 0 Pes-10 MacB_PCD PF12704.7 KFX94749.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 MacB-like periplasmic core domain MDM10 PF12519.8 KFX94750.1 - 0.58 8.9 2.2 0.65 8.8 2.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Endostatin PF06482.11 KFX94750.1 - 0.76 9.2 5.9 0.93 8.9 5.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 KFX94750.1 - 0.81 8.6 6.4 0.92 8.4 6.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 KFX94750.1 - 1.9 9.1 13.1 2.1 9.0 13.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 KFX94750.1 - 4.5 6.7 11.0 4.9 6.6 11.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 KFX94750.1 - 6.9 4.8 6.2 6.7 4.9 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein POP1 PF06978.11 KFX94752.1 - 7e-72 241.7 7.0 7e-72 241.7 7.0 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFX94752.1 - 2e-30 104.9 0.4 5.4e-30 103.6 0.4 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF4596 PF15363.6 KFX94752.1 - 5.9 7.2 8.0 9.4 6.6 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Redoxin PF08534.10 KFX94753.1 - 4.6e-34 117.3 0.0 5.2e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFX94753.1 - 5.5e-12 45.7 0.0 6.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 KFX94754.1 - 1.8e-63 212.3 4.9 2.1e-63 212.1 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KFX94754.1 - 1.8e-08 35.0 1.1 2.4e-08 34.6 1.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFX94754.1 - 4e-06 27.2 0.1 5.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Y_phosphatase3 PF13350.6 KFX94755.1 - 1.4e-57 195.4 0.0 1.6e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX94755.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFX94755.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFX94755.1 - 0.057 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_3_C PF01915.22 KFX94756.1 - 1.2e-47 162.5 0.0 2.6e-47 161.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX94756.1 - 1.7e-40 139.4 0.0 2.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX94756.1 - 9e-22 77.0 0.0 2e-21 75.8 0.0 1.6 1 1 0 1 1 1 1 Fibronectin type III-like domain Endotoxin_C2 PF18449.1 KFX94756.1 - 0.048 14.0 0.1 0.69 10.3 0.5 2.3 2 0 0 2 2 2 0 Delta endotoxin SNARE PF05739.19 KFX94756.1 - 0.095 12.7 3.3 0.19 11.8 3.3 1.4 1 0 0 1 1 1 0 SNARE domain DUF4797 PF16051.5 KFX94756.1 - 1.1 9.2 3.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) Dala_Dala_lig_C PF07478.13 KFX94757.1 - 9.9e-26 90.5 0.0 1.4e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KFX94757.1 - 0.00057 19.5 0.0 0.0022 17.5 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KFX94757.1 - 0.00058 19.9 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX94757.1 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Glyco_hydro_16 PF00722.21 KFX94758.1 - 8.7e-06 25.3 0.2 2.7e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2235 PF09994.9 KFX94759.1 - 1.4e-85 287.2 0.1 2.1e-85 286.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KFX94759.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RecA_dep_nuc PF16786.5 KFX94759.1 - 0.11 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease An_peroxidase PF03098.15 KFX94760.1 - 4.5e-37 127.8 0.7 5.9e-10 38.3 0.1 4.0 2 1 2 4 4 4 4 Animal haem peroxidase p450 PF00067.22 KFX94760.1 - 5.8e-10 38.5 0.1 2.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cellulase PF00150.18 KFX94762.1 - 4.3e-56 190.4 0.1 5.3e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RGS PF00615.19 KFX94763.1 - 2.2e-09 37.6 0.0 3.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain MPC PF03650.13 KFX94764.1 - 7.7e-46 154.8 1.0 1e-45 154.4 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 KFX94765.1 - 7.3e-13 48.2 0.0 9.1e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Tub_N PF16322.5 KFX94767.1 - 1.9 8.9 9.3 2.5 8.5 9.3 1.3 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 KFX94767.1 - 2.1 7.6 14.5 2.4 7.4 14.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KFX94767.1 - 5 6.5 14.8 6 6.2 14.8 1.2 1 0 0 1 1 1 0 SDA1 Ribosomal_60s PF00428.19 KFX94767.1 - 7.7 7.2 11.7 1.6 9.3 4.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABA_GPCR PF12430.8 KFX94768.1 - 3.6e-56 189.8 0.4 4.8e-55 186.1 0.1 2.1 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFX94768.1 - 7.1e-24 83.7 0.0 1.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Usp PF00582.26 KFX94769.1 - 2.3e-17 63.8 0.0 6.3e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family Paf67 PF10255.9 KFX94770.1 - 4.2e-157 523.3 0.2 4.9e-157 523.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFX94770.1 - 0.025 14.7 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_occluded PF16842.5 KFX94771.1 - 0.03 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ku_PK_bind PF08785.11 KFX94772.1 - 3.2e-31 108.0 0.0 6.3e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KFX94772.1 - 3.6e-28 98.7 0.0 7.9e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFX94772.1 - 1.5e-12 47.7 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KFX94772.1 - 1.7e-05 25.1 0.1 4.6e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Curto_V2 PF07325.11 KFX94772.1 - 0.026 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Curtovirus V2 protein DUF4149 PF13664.6 KFX94773.1 - 1.7e-25 89.3 2.9 1.7e-25 89.3 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MatE PF01554.18 KFX94774.1 - 1.3e-52 177.8 24.3 2.3e-35 121.6 6.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFX94774.1 - 6.8 6.8 39.7 0.038 14.1 17.0 4.1 3 2 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain SnoaL PF07366.12 KFX94775.1 - 1.1e-24 86.6 0.0 1.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFX94775.1 - 3.9e-12 46.7 0.0 6.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2686 PF10887.8 KFX94775.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Stb3 PF10330.9 KFX94776.1 - 3.5e-39 132.7 0.0 5.9e-39 132.0 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.20 KFX94778.1 - 1.9e-101 340.1 0.0 4.2e-95 319.2 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KFX94778.1 - 7.8e-20 71.0 0.0 2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain PRR20 PF15708.5 KFX94778.1 - 0.017 15.0 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 DUF1295 PF06966.12 KFX94779.1 - 5.2e-34 117.8 7.5 6.6e-34 117.5 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DPM2 PF07297.12 KFX94782.1 - 7.2e-32 109.5 1.4 1e-31 109.1 1.4 1.2 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KFX94782.1 - 0.012 15.6 6.1 0.013 15.4 5.5 1.4 1 1 0 1 1 1 0 PIG-P DUF4229 PF14012.6 KFX94782.1 - 0.019 15.0 0.9 0.019 15.0 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Phage_holin_3_6 PF07332.11 KFX94782.1 - 0.031 14.3 1.1 0.043 13.8 1.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cytochrom_C_asm PF01578.20 KFX94782.1 - 0.044 13.5 0.8 0.053 13.3 0.8 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein LapA_dom PF06305.11 KFX94782.1 - 0.34 10.7 0.1 0.34 10.7 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MA3 PF02847.17 KFX94783.1 - 1.1e-28 99.5 0.0 3.4e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 MA3 domain Na_trans_assoc PF06512.13 KFX94783.1 - 0.26 11.6 7.9 0.54 10.5 7.9 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated DUF5523 PF17661.1 KFX94783.1 - 3.5 7.2 12.9 0.58 9.8 9.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) CENP-K PF11802.8 KFX94785.1 - 0.02 14.4 6.6 0.034 13.7 6.6 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Spectrin PF00435.21 KFX94785.1 - 0.43 11.1 6.7 24 5.5 4.4 2.7 2 0 0 2 2 2 0 Spectrin repeat GTP-bdg_M PF16360.5 KFX94785.1 - 0.48 11.0 13.2 0.77 10.4 3.4 2.9 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region JIP_LZII PF16471.5 KFX94785.1 - 0.63 10.3 4.6 3.5 7.9 1.0 2.7 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Pox_A_type_inc PF04508.12 KFX94785.1 - 1.4 8.9 7.1 14 5.7 1.9 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ERM PF00769.19 KFX94785.1 - 8.4 6.1 23.2 24 4.6 22.8 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Glyco_hydro_72 PF03198.14 KFX94793.1 - 3e-113 378.2 0.1 3.7e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KFX94793.1 - 8.4e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KFX94793.1 - 0.088 12.2 0.3 3.7 6.9 0.3 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Citrate_bind PF16114.5 KFX94794.1 - 7.3e-88 292.7 0.0 1e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KFX94794.1 - 1e-06 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KFX94794.1 - 0.058 11.5 0.0 0.079 11.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 KFX94795.1 - 3.2e-20 72.5 0.0 2.9e-17 62.8 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KFX94795.1 - 3.2e-19 69.4 0.0 1.2e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFX94795.1 - 2.3e-13 50.2 0.1 4.1e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFX94795.1 - 7.4e-05 22.6 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L18 PF17135.4 KFX94797.1 - 3.3e-67 225.5 1.0 3.7e-67 225.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KFX94797.1 - 0.0044 17.7 1.5 0.0056 17.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 KFX94798.1 - 1.1e-72 240.1 4.9 3.9e-24 84.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX94798.1 - 0.00075 18.7 1.4 0.024 13.8 0.0 3.0 2 1 2 4 4 4 1 Gammaproteobacterial serine protease PT-VENN PF04829.13 KFX94798.1 - 2.7 8.1 4.3 15 5.8 0.1 3.0 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 KFX94799.1 - 4e-12 45.8 0.0 5.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX94799.1 - 0.00083 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SWIRM-assoc_2 PF16496.5 KFX94799.1 - 2.3 7.0 8.4 2.8 6.7 8.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CH PF00307.31 KFX94800.1 - 1.5e-73 244.0 0.1 4.5e-20 71.9 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFX94800.1 - 2.3e-06 28.0 1.2 3.7e-05 24.1 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFX94800.1 - 0.00018 20.8 1.7 0.25 11.0 0.4 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFX94800.1 - 0.0024 17.7 3.6 0.076 13.0 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFX94800.1 - 0.18 11.4 3.2 0.79 9.3 0.4 2.9 2 0 0 2 2 2 0 EF hand DWNN PF08783.11 KFX94801.1 - 1.2e-31 108.8 0.1 2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KFX94801.1 - 1.2e-08 34.6 4.7 2.2e-08 33.8 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFX94801.1 - 0.00038 20.4 1.0 0.00074 19.5 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KFX94801.1 - 0.0019 18.0 9.1 0.0019 18.0 9.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KFX94801.1 - 0.0027 17.8 0.1 0.0074 16.4 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KFX94801.1 - 0.032 14.1 4.8 0.072 12.9 4.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-DNL PF05180.12 KFX94801.1 - 0.038 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 DNL zinc finger DUF3332 PF11810.8 KFX94801.1 - 0.15 11.7 0.8 0.29 10.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) zf-RING_4 PF14570.6 KFX94801.1 - 0.15 11.9 5.8 0.32 10.8 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFX94801.1 - 0.21 12.0 6.8 0.44 10.9 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KFX94801.1 - 0.24 11.6 9.2 0.81 9.9 9.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFX94801.1 - 0.58 10.2 7.0 1.1 9.3 7.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFX94801.1 - 0.65 9.9 9.2 1.3 8.9 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX94801.1 - 2.5 8.1 11.6 0.31 11.0 6.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.21 KFX94802.1 - 4.8e-46 157.1 1.0 2.1e-45 155.0 1.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KFX94802.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KFX94802.1 - 2.4e-11 43.9 0.0 4.9e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFX94802.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KFX94802.1 - 0.009 15.8 0.1 0.089 12.6 0.0 2.4 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 KFX94802.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 Peptidase_S51 PF03575.17 KFX94802.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 dCMP_cyt_deam_1 PF00383.23 KFX94803.1 - 7.4e-29 99.6 1.0 1.2e-28 98.9 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFX94803.1 - 2.4e-11 43.5 0.1 4.7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KFX94803.1 - 0.00068 20.2 0.1 0.0024 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KFX94803.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase ATG7_N PF16420.5 KFX94804.1 - 3.3e-109 365.1 0.0 4.3e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFX94804.1 - 9.9e-43 146.2 0.0 1.4e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFX94804.1 - 0.01 15.9 0.1 0.088 12.9 0.0 2.3 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase COPIIcoated_ERV PF07970.12 KFX94804.1 - 0.11 12.3 0.3 0.2 11.5 0.3 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter 2-Hacid_dh_C PF02826.19 KFX94804.1 - 0.13 11.6 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MIT PF04212.18 KFX94805.1 - 1.3e-14 54.0 0.4 3.3e-14 52.7 0.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PXA PF02194.15 KFX94806.1 - 4e-30 105.1 0.1 2.6e-29 102.5 0.1 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFX94806.1 - 9.5e-24 84.1 0.0 3.4e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFX94806.1 - 2.6e-08 33.8 0.0 2.2e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 PX domain PC4 PF02229.16 KFX94807.1 - 4.6e-20 71.0 0.0 7e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DDHD PF02862.17 KFX94808.1 - 9e-64 215.7 1.4 2.6e-63 214.2 0.0 2.4 2 1 0 2 2 2 1 DDHD domain AAR2 PF05282.11 KFX94808.1 - 0.037 13.4 0.1 0.079 12.4 0.1 1.5 1 0 0 1 1 1 0 AAR2 protein DUF676 PF05057.14 KFX94808.1 - 0.15 11.5 0.2 1.2 8.7 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Ku PF02735.16 KFX94811.1 - 6.4e-47 159.9 0.0 1.1e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFX94811.1 - 3.3e-34 118.6 0.0 4.5e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KFX94811.1 - 5.9e-23 81.4 1.2 1.3e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KFX94811.1 - 6.1e-10 38.6 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain HsbA PF12296.8 KFX94822.1 - 8.2e-26 90.8 14.2 1.4e-25 90.1 14.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KFX94822.1 - 0.0028 17.7 4.9 0.077 13.0 1.7 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Dimerisation2 PF16864.5 KFX94822.1 - 0.036 14.0 1.1 0.064 13.2 0.2 1.8 2 0 0 2 2 2 0 Dimerisation domain NPV_P10 PF05531.12 KFX94822.1 - 1.5 9.3 4.5 5.7 7.5 0.2 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAT PF03417.16 KFX94823.1 - 7.4e-19 68.3 0.0 3.7e-17 62.8 0.0 2.7 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TRAPP PF04051.16 KFX94824.1 - 3.4e-35 120.9 0.1 4e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KFX94824.1 - 0.06 12.2 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 KFX94825.1 - 3.7e-40 135.2 8.4 5.9e-08 33.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94825.1 - 1.5e-12 47.6 0.3 0.0014 18.9 0.0 4.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX94825.1 - 0.0021 17.1 0.0 0.38 9.7 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX94825.1 - 0.015 14.6 0.0 9.3 5.5 0.0 3.0 2 1 0 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 KFX94825.1 - 0.083 11.6 0.1 1.5 7.5 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like Abhydrolase_3 PF07859.13 KFX94834.1 - 1.3e-34 120.0 0.0 3.1e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFX94834.1 - 4.3e-06 25.9 0.0 7.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Molybdopterin_N PF18364.1 KFX94834.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain Abhydrolase_2 PF02230.16 KFX94834.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KFX94834.1 - 0.21 11.0 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Mito_carr PF00153.27 KFX94836.1 - 5.4e-55 183.3 4.0 1e-18 67.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFX94837.1 - 4.1e-16 59.1 0.2 9.3e-08 32.6 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94837.1 - 1.5e-09 38.0 0.0 0.13 12.5 0.0 4.9 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 KFX94837.1 - 0.01 14.3 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3823 PF12866.7 KFX94837.1 - 0.05 13.9 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain EAF PF09816.9 KFX94837.1 - 0.12 12.8 0.8 0.63 10.5 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription elongation factor DUF2818 PF10993.8 KFX94838.1 - 0.18 12.4 3.1 1.4 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Claudin_2 PF13903.6 KFX94838.1 - 2.7 7.7 9.0 0.55 10.0 0.2 2.8 1 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction COX5B PF01215.19 KFX94843.1 - 9.8e-57 190.2 0.0 1.3e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.10 KFX94843.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain AAA PF00004.29 KFX94844.1 - 7.3e-97 320.9 0.0 3.9e-47 160.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX94844.1 - 1.1e-24 85.9 6.5 2.2e-13 49.8 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KFX94844.1 - 2.9e-19 69.0 0.3 9.5e-19 67.4 0.3 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFX94844.1 - 1.3e-13 51.0 0.0 1.9e-05 24.4 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFX94844.1 - 1.5e-13 51.2 0.0 2.6e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFX94844.1 - 6.4e-13 49.1 0.0 1.1e-05 25.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KFX94844.1 - 9e-12 45.7 0.0 0.00012 22.6 0.0 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KFX94844.1 - 6.2e-11 42.5 0.4 1.5e-05 25.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFX94844.1 - 4.5e-09 36.0 0.0 0.0017 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KFX94844.1 - 8.1e-09 35.9 0.5 0.057 13.7 0.0 4.4 2 2 3 5 5 4 2 AAA domain CDC48_2 PF02933.17 KFX94844.1 - 4.8e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KFX94844.1 - 5.8e-07 29.1 0.2 0.037 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFX94844.1 - 8.6e-07 28.9 0.0 0.046 13.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KFX94844.1 - 1.6e-06 28.2 0.0 0.02 15.0 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.6 KFX94844.1 - 1.6e-06 28.7 0.0 0.04 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFX94844.1 - 3e-06 27.6 0.0 0.041 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KFX94844.1 - 3.1e-06 26.7 0.2 0.61 9.4 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KFX94844.1 - 3.6e-06 26.6 0.1 0.034 13.7 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KFX94844.1 - 9e-06 25.6 0.2 5.9e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KFX94844.1 - 3.8e-05 23.0 0.0 0.017 14.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX94844.1 - 4e-05 23.4 0.0 0.39 10.4 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 KFX94844.1 - 5.1e-05 23.6 0.0 0.34 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFX94844.1 - 6.3e-05 22.5 0.1 0.4 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 KFX94844.1 - 6.9e-05 23.4 0.0 0.33 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.17 KFX94844.1 - 8.6e-05 21.8 0.0 0.083 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KFX94844.1 - 0.00016 21.5 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFX94844.1 - 0.00019 21.1 4.7 1.4 8.4 0.1 4.6 3 2 2 5 5 5 1 AAA domain AAA_17 PF13207.6 KFX94844.1 - 0.0003 21.2 0.0 0.88 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain Bac_DnaA PF00308.18 KFX94844.1 - 0.00034 20.5 0.0 0.86 9.4 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_3 PF07726.11 KFX94844.1 - 0.00058 19.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFX94844.1 - 0.00074 19.5 0.0 0.66 10.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KFX94844.1 - 0.00077 19.5 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KFX94844.1 - 0.00087 19.2 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KFX94844.1 - 0.0016 17.8 0.0 0.69 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFX94844.1 - 0.0023 17.7 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFX94844.1 - 0.006 16.9 0.6 9.3 6.6 0.0 3.4 3 1 1 4 4 2 0 AAA domain ATPase_2 PF01637.18 KFX94844.1 - 0.0064 16.4 0.0 10 5.9 0.0 3.5 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KFX94844.1 - 0.0084 16.2 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KFX94844.1 - 0.01 15.7 0.1 3 7.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.18 KFX94844.1 - 0.012 15.4 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.16 KFX94844.1 - 0.016 14.6 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 KFX94844.1 - 0.02 14.1 0.0 0.91 8.7 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 KFX94844.1 - 0.023 13.9 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KFX94844.1 - 0.033 13.5 0.0 7.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KFX94844.1 - 0.037 13.9 2.4 3.3 7.6 0.0 4.1 4 0 0 4 4 4 0 NTPase UFD1 PF03152.14 KFX94844.1 - 0.043 13.3 0.0 0.15 11.5 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin2 PF13189.6 KFX94844.1 - 0.066 13.3 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KFX94844.1 - 0.083 12.6 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 KFX94844.1 - 0.2 11.3 0.0 10 5.7 0.0 2.8 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KFX94844.1 - 0.2 10.6 0.0 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Adeno_PV PF03910.13 KFX94846.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV zf-C2H2 PF00096.26 KFX94847.1 - 4.1e-08 33.2 12.1 3.4e-05 24.1 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX94847.1 - 1.6e-05 25.4 10.0 0.025 15.4 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.18 KFX94847.1 - 3.7e-05 22.9 0.0 5.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_6 PF13912.6 KFX94847.1 - 6.2e-05 22.9 8.9 0.085 12.9 6.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX94847.1 - 9.1e-05 22.6 0.7 0.1 12.9 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFX94847.1 - 0.00056 20.2 21.4 0.00071 19.9 3.6 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 KFX94847.1 - 0.053 13.9 0.3 10 6.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.22 KFX94847.1 - 0.19 12.0 3.0 0.53 10.5 3.0 1.8 1 1 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 KFX94847.1 - 1 9.2 0.1 1 9.2 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KFX94847.1 - 1.4 9.0 4.7 3.8 7.6 4.7 1.8 1 0 0 1 1 1 0 BED zinc finger zf-LYAR PF08790.11 KFX94847.1 - 2 8.4 5.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFX94847.1 - 4.6 7.5 5.6 1.2 9.5 2.3 1.7 2 0 0 2 2 1 0 TFIIH C1-like domain MFS_1 PF07690.16 KFX94848.1 - 2.6e-40 138.4 21.1 2.6e-40 138.4 21.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX94848.1 - 2e-09 36.9 4.9 2e-09 36.9 4.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KFX94848.1 - 2.8e-08 32.7 6.3 2.3e-07 29.6 2.1 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFX94848.1 - 0.00073 18.2 2.1 0.00073 18.2 2.1 2.5 2 2 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 KFX94848.1 - 0.0029 16.7 0.2 0.27 10.2 0.1 2.3 2 0 0 2 2 2 2 PUCC protein DUF1361 PF07099.11 KFX94848.1 - 0.061 13.3 2.6 0.083 12.9 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) FAD_binding_3 PF01494.19 KFX94849.1 - 9e-21 74.5 0.0 1e-12 48.0 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX94849.1 - 2.4e-08 34.1 0.4 6.7e-08 32.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX94849.1 - 2.1e-05 23.9 0.2 0.0016 17.8 0.4 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX94849.1 - 6.1e-05 22.8 0.7 0.00081 19.1 0.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX94849.1 - 0.0014 17.8 2.7 0.0031 16.7 2.4 1.7 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFX94849.1 - 0.0037 16.5 0.2 0.0057 15.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFX94849.1 - 0.0045 16.3 0.5 0.0095 15.2 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX94849.1 - 0.0092 14.9 0.2 0.017 14.0 0.2 1.4 1 0 0 1 1 1 1 Tryptophan halogenase ThiF PF00899.21 KFX94849.1 - 0.017 14.5 0.3 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 KFX94849.1 - 0.028 15.0 0.2 0.082 13.5 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX94849.1 - 0.059 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX94849.1 - 0.093 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KFX94849.1 - 0.096 11.7 2.2 0.077 12.1 0.8 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFX94849.1 - 0.11 11.2 0.4 0.17 10.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF3500 PF12006.8 KFX94850.1 - 3.7e-102 341.8 0.0 4.5e-102 341.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) SSP160 PF06933.11 KFX94851.1 - 0.0075 14.5 5.8 0.01 14.1 5.8 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Pilin_N PF07790.11 KFX94851.1 - 0.015 16.2 0.7 0.028 15.3 0.7 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal PilX_N PF14341.6 KFX94851.1 - 0.04 13.9 0.3 0.087 12.8 0.3 1.5 1 0 0 1 1 1 0 PilX N-terminal PAN_1 PF00024.26 KFX94851.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 PAN domain DUF4834 PF16118.5 KFX94851.1 - 0.073 14.0 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2749 PF10907.8 KFX94851.1 - 0.3 11.3 1.5 0.84 9.9 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Peptidase_C15 PF01470.17 KFX94852.1 - 0.013 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Pyroglutamyl peptidase Glyco_trans_4_2 PF13477.6 KFX94852.1 - 0.036 14.1 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like B12-binding PF02310.19 KFX94852.1 - 0.099 12.7 0.0 3.7 7.6 0.0 2.0 1 1 0 2 2 2 0 B12 binding domain FAA_hydrolase PF01557.18 KFX94853.1 - 8.4e-54 182.5 0.0 1.1e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cyanate_lyase PF02560.14 KFX94854.1 - 7.9e-31 105.7 0.0 1.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 KFX94854.1 - 0.00074 19.1 0.0 0.0018 17.9 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 KFX94854.1 - 0.0046 17.0 0.1 0.008 16.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KFX94854.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3786 PF12654.7 KFX94854.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Arm PF00514.23 KFX94855.1 - 2.8e-94 306.6 17.3 2.7e-13 49.4 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFX94855.1 - 8.3e-27 93.5 1.7 8.3e-27 93.5 1.7 2.1 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KFX94855.1 - 1.1e-21 76.2 4.5 2.7e-21 74.9 4.5 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFX94855.1 - 7.9e-21 74.2 10.0 6.4e-08 32.9 0.1 6.5 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KFX94855.1 - 5e-19 68.5 1.3 1.8e-08 34.6 0.1 5.8 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KFX94855.1 - 2.2e-17 61.7 3.3 8.8e-05 22.4 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KFX94855.1 - 1.4e-07 31.3 0.0 0.006 16.1 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KFX94855.1 - 2.7e-05 22.9 0.0 0.0041 15.7 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFX94855.1 - 4.1e-05 23.7 0.0 2.5 8.3 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H NopRA1 PF16201.5 KFX94855.1 - 0.0064 16.1 0.0 4.2 6.9 0.0 3.8 1 1 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 KFX94855.1 - 0.0067 17.0 3.1 1.9 9.4 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KFX94855.1 - 0.056 13.7 4.9 3.5 7.9 0.0 4.5 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 KFX94856.1 - 1.8e-33 115.6 0.4 7.1e-33 113.7 0.1 2.2 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFX94856.1 - 3.6e-11 43.1 0.0 8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF3328 PF11807.8 KFX94862.1 - 7.2e-24 84.8 0.0 1.1e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_115 PF15979.5 KFX94864.1 - 2.6e-134 448.0 1.8 3.4e-134 447.6 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KFX94864.1 - 6.7e-60 201.8 0.0 1.9e-59 200.4 0.0 1.8 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Collagen PF01391.18 KFX94864.1 - 0.014 15.2 10.3 0.028 14.2 10.3 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Zn_clus PF00172.18 KFX94865.1 - 0.24 11.5 24.6 0.65 10.2 5.9 3.9 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain E7 PF00527.18 KFX94865.1 - 0.62 10.3 6.7 0.062 13.5 0.8 2.4 2 0 0 2 2 2 0 E7 protein, Early protein CENP-B_dimeris PF09026.10 KFX94865.1 - 0.64 10.4 9.3 0.16 12.4 0.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sedlin_N PF04628.13 KFX94866.1 - 9.8e-12 45.1 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Nucleoporin_C PF03177.14 KFX94867.1 - 1.5e-119 400.4 2.1 2e-119 400.1 2.1 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KFX94867.1 - 4.1e-72 243.3 0.0 5.5e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF2052 PF09747.9 KFX94878.1 - 0.055 13.6 10.0 0.46 10.6 3.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AA_permease PF00324.21 KFX94881.1 - 2.2e-126 422.3 43.0 2.6e-126 422.0 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX94881.1 - 1.9e-28 99.5 47.7 2.4e-28 99.1 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 KFX94881.1 - 8.4 6.9 19.0 1 9.9 4.5 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) LSM PF01423.22 KFX94882.1 - 1.1e-14 53.9 0.2 1.3e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFX94882.1 - 0.00047 19.7 0.1 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein GRDP-like PF07173.12 KFX94885.1 - 6.1e-15 56.1 3.9 1.6e-12 48.3 0.3 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Peptidase_S32 PF05579.13 KFX94885.1 - 0.0082 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 NUDIX PF00293.28 KFX94885.1 - 0.031 14.3 0.0 0.084 12.9 0.0 1.8 1 0 0 1 1 1 0 NUDIX domain Sugar_tr PF00083.24 KFX94887.1 - 2.7e-35 122.1 32.1 1.3e-21 77.0 15.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX94887.1 - 4.2e-19 68.7 41.5 7.2e-10 38.3 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gate PF07670.14 KFX94887.1 - 4.7 7.5 13.0 4.1 7.7 6.6 2.8 2 1 0 2 2 2 0 Nucleoside recognition CTP_transf_like PF01467.26 KFX94888.1 - 2.1e-24 86.3 0.0 3.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like ABC2_membrane PF01061.24 KFX94890.1 - 4.3e-87 290.9 55.7 1.4e-48 165.1 22.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX94890.1 - 5e-36 124.2 0.0 2.4e-17 63.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX94890.1 - 9.3e-36 121.6 2.2 5.1e-28 96.8 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX94890.1 - 9.1e-21 74.3 0.0 3.7e-20 72.3 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFX94890.1 - 4.1e-07 30.5 0.2 0.0036 17.7 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX94890.1 - 5.1e-06 26.2 0.1 4.4e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFX94890.1 - 5.9e-06 26.3 0.1 0.00091 19.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KFX94890.1 - 6.2e-05 22.3 6.9 6.2e-05 22.3 6.9 3.8 2 2 0 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.6 KFX94890.1 - 0.00014 22.1 0.7 0.034 14.3 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 KFX94890.1 - 0.00033 20.6 0.7 0.51 10.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX94890.1 - 0.00049 19.8 1.4 0.05 13.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFX94890.1 - 0.001 19.6 0.0 0.052 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFX94890.1 - 0.0077 15.7 0.0 0.44 9.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX94890.1 - 0.0079 16.5 0.1 2.3 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFX94890.1 - 0.008 15.9 0.3 0.87 9.3 0.3 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX94890.1 - 0.075 12.9 1.6 2.6 7.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KFX94890.1 - 0.12 12.5 0.3 19 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KFX94890.1 - 0.12 12.8 0.3 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFX94890.1 - 0.58 9.7 2.4 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DASH_Spc19 PF08287.11 KFX94892.1 - 3.5e-27 95.2 0.0 5.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 KFX94892.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase middle domain SepZ PF06066.11 KFX94896.1 - 0.028 14.6 1.6 0.036 14.3 0.2 1.8 2 0 0 2 2 2 0 SepZ KxDL PF10241.9 KFX94896.1 - 0.083 13.2 9.1 0.37 11.1 2.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein HOOK PF05622.12 KFX94896.1 - 0.95 7.5 20.0 2.3 6.3 20.0 1.5 1 1 0 1 1 1 0 HOOK protein PKcGMP_CC PF16808.5 KFX94896.1 - 1.3 8.9 13.0 2 8.3 0.0 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KFX94896.1 - 2.3 8.6 11.4 4.6 7.7 4.5 3.6 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2968 PF11180.8 KFX94896.1 - 2.6 7.7 21.6 0.17 11.5 10.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.21 KFX94896.1 - 4.9 7.3 13.4 1.3 9.2 2.6 4.3 3 0 0 3 3 3 0 bZIP transcription factor HIP1_clath_bdg PF16515.5 KFX94896.1 - 4.9 7.8 20.2 17 6.1 3.2 3.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 KFX94896.1 - 5.6 7.4 6.5 13 6.3 1.7 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HR1 PF02185.16 KFX94896.1 - 6.7 6.9 11.5 6.4 7.0 2.7 3.0 2 0 0 2 2 2 0 Hr1 repeat DUF4349 PF14257.6 KFX94896.1 - 7.3 6.0 19.6 0.18 11.2 5.8 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) PGPGW PF09656.10 KFX94897.1 - 0.067 12.7 0.5 0.16 11.5 0.5 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Sugar_tr PF00083.24 KFX94900.1 - 2.2e-72 244.3 29.2 2.6e-72 244.1 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94900.1 - 1.2e-13 50.8 30.2 1.2e-13 50.8 30.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX94900.1 - 1.3 7.7 25.4 0.31 9.8 10.3 2.4 2 1 0 2 2 2 0 MFS_1 like family DUF1961 PF09224.11 KFX94901.1 - 6.5e-98 326.3 0.0 7.4e-98 326.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) Ammonium_transp PF00909.21 KFX94902.1 - 1.9e-109 366.0 30.8 2.2e-109 365.8 30.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CRT10 PF08728.10 KFX94904.1 - 3e-06 25.7 0.1 5e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 CRT10 MMR_HSR1_Xtn PF16897.5 KFX94907.1 - 3.6e-39 133.0 0.3 3.6e-39 133.0 0.3 2.3 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFX94907.1 - 3.2e-22 78.3 0.1 7.3e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFX94907.1 - 4.4e-22 78.3 0.1 1.8e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX94907.1 - 1.1e-09 38.0 0.0 5.3e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX94907.1 - 0.00072 19.7 0.1 0.18 11.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFX94907.1 - 0.0014 18.2 1.3 8.1 5.9 0.0 4.2 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFX94907.1 - 0.0087 15.1 0.1 0.02 13.9 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFX94907.1 - 0.026 14.5 1.3 2.6 7.9 0.1 3.1 2 1 1 3 3 3 0 RsgA GTPase Arf PF00025.21 KFX94907.1 - 0.048 13.1 0.2 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Steroid_dh PF02544.16 KFX94908.1 - 1.7e-10 41.1 0.4 7.7e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFX94908.1 - 0.0084 15.7 0.4 0.016 14.7 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_18A PF09771.9 KFX94908.1 - 0.075 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Phage_FRD3 PF05798.11 KFX94908.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage FRD3 protein 2OG-FeII_Oxy_2 PF13532.6 KFX94909.1 - 1.8e-12 47.9 0.0 2.1e-11 44.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KFX94910.1 - 1.7e-21 76.6 0.6 6.8e-10 39.4 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94910.1 - 2.8e-17 62.8 0.2 5.6e-08 33.2 0.1 4.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX94910.1 - 1.5e-14 53.8 0.5 0.00055 20.2 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94910.1 - 1e-11 43.9 1.4 0.0011 19.2 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KFX94910.1 - 1.6e-11 44.1 4.5 0.00059 20.2 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat AMP-binding PF00501.28 KFX94920.1 - 1.6e-35 122.5 0.0 2.1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX94920.1 - 2.3e-09 38.1 0.0 6.5e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KFX94921.1 - 8e-25 87.3 0.0 1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme OTU PF02338.19 KFX94922.1 - 1.4e-20 74.1 0.5 2.9e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFX94922.1 - 0.002 17.6 0.8 0.12 11.7 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF4407 PF14362.6 KFX94922.1 - 0.2 11.0 13.6 0.35 10.2 13.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFR_dimer PF04253.15 KFX94922.1 - 1.2 9.3 6.5 0.094 12.8 1.1 1.8 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain TPMT PF05724.11 KFX94923.1 - 2.1e-26 93.0 0.0 3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KFX94923.1 - 8.7e-05 22.4 0.0 0.00029 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX94923.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX94923.1 - 0.0012 19.4 0.0 0.0029 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX94923.1 - 0.0019 18.9 0.0 0.0042 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX94923.1 - 0.0022 18.7 0.0 0.0036 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFX94923.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB SHMT PF00464.19 KFX94924.1 - 2.9e-200 664.9 0.0 3.7e-200 664.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase adh_short_C2 PF13561.6 KFX94924.1 - 6.3e-46 156.8 0.0 1e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX94924.1 - 6.7e-44 149.7 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX94924.1 - 5e-06 26.6 0.0 1.7e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 KR domain Gcn1_N PF12074.8 KFX94926.1 - 5.5e-119 397.6 4.2 5.5e-119 397.6 4.2 3.8 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KFX94926.1 - 2.4e-59 199.5 6.2 6.8e-59 198.1 6.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_EZ PF13513.6 KFX94926.1 - 2.4e-31 107.7 28.8 1.3e-06 28.8 0.0 17.6 14 3 5 19 19 18 8 HEAT-like repeat HEAT PF02985.22 KFX94926.1 - 1.1e-27 93.7 25.7 0.25 11.7 0.0 20.0 22 0 0 22 22 20 6 HEAT repeat HEAT_2 PF13646.6 KFX94926.1 - 1.7e-21 76.4 38.4 0.00021 21.6 0.0 14.2 10 4 7 17 17 15 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX94926.1 - 3.4e-13 50.0 0.0 3.2 8.4 0.0 10.3 8 2 2 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFX94926.1 - 4.2e-12 46.4 3.8 1.2 9.2 0.1 8.9 6 3 2 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KFX94926.1 - 2.6e-10 40.7 3.2 0.0034 17.5 0.0 7.0 8 1 0 8 8 7 2 Parkin co-regulated protein CLASP_N PF12348.8 KFX94926.1 - 1.2e-08 34.8 0.0 0.23 11.0 0.0 5.5 4 1 1 5 5 5 2 CLASP N terminal TIP120 PF08623.10 KFX94926.1 - 4.5e-05 23.3 0.0 0.018 14.8 0.0 5.1 4 2 1 5 5 5 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 KFX94926.1 - 0.00096 18.4 0.2 0.00096 18.4 0.2 7.1 7 1 1 8 8 8 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KFX94926.1 - 0.0016 18.4 0.0 1.2 9.0 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KFX94926.1 - 0.0031 17.1 4.9 0.29 10.6 0.0 5.7 6 0 0 6 6 6 1 Tti2 family Mac-1 PF09028.10 KFX94926.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Mac 1 RTP1_C1 PF10363.9 KFX94926.1 - 0.054 13.7 1.3 85 3.4 0.0 5.6 5 1 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF937 PF06078.11 KFX94926.1 - 0.1 13.2 7.8 6.8 7.3 0.0 5.6 6 1 0 6 6 5 0 Bacterial protein of unknown function (DUF937) MarR_2 PF12802.7 KFX94926.1 - 0.14 12.1 0.6 15 5.5 0.0 3.0 2 0 0 2 2 2 0 MarR family Atypical_Card PF18461.1 KFX94926.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Atypical caspase recruitment domain RIX1 PF08167.12 KFX94926.1 - 0.24 11.1 2.4 1.1 9.0 0.3 3.4 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis U3snoRNP10 PF12397.8 KFX94926.1 - 4.7 7.6 8.0 82 3.6 0.0 6.0 5 1 1 6 6 4 0 U3 small nucleolar RNA-associated protein 10 HA2 PF04408.23 KFX94927.1 - 2.2e-14 53.6 0.5 8e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX94927.1 - 1.4e-13 51.1 0.0 3.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX94927.1 - 7.6e-12 45.4 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KFX94927.1 - 4.1e-07 30.3 0.1 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KFX94927.1 - 6.2e-07 29.8 0.1 2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFX94927.1 - 0.0027 18.2 0.1 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KFX94927.1 - 0.0029 17.3 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 KFX94927.1 - 0.025 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 KFX94927.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFX94927.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KFX94927.1 - 0.78 10.2 0.0 0.78 10.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain ACPS PF01648.20 KFX94931.1 - 0.00046 20.3 0.0 0.0009 19.4 0.0 1.5 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KFX94931.1 - 0.0026 17.8 0.2 0.39 10.9 0.0 2.8 3 0 0 3 3 3 2 4'-phosphopantetheinyl transferase N-terminal domain AAA PF00004.29 KFX94934.1 - 1.9e-16 60.7 0.0 8.4e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX94934.1 - 0.0014 18.9 0.7 0.019 15.2 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX94934.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Macoilin PF09726.9 KFX94934.1 - 0.002 16.8 24.2 0.0038 15.9 24.2 1.4 1 0 0 1 1 1 1 Macoilin family AAA_16 PF13191.6 KFX94934.1 - 0.036 14.5 0.9 0.24 11.8 0.9 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFX94934.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFX94934.1 - 0.12 12.1 0.0 0.12 12.1 0.0 3.7 3 2 0 3 3 3 0 AAA domain Glyco_hydro_36 PF17167.4 KFX94935.1 - 4e-63 213.6 0.1 9.6e-63 212.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 KFX94935.1 - 1.6e-27 96.6 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 KFX94935.1 - 0.00046 19.6 0.3 0.00094 18.5 0.1 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_65C PF03633.15 KFX94935.1 - 0.0022 17.8 0.1 0.0073 16.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain GDE_C PF06202.14 KFX94935.1 - 0.0072 15.3 0.0 0.018 14.0 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase ABC2_membrane PF01061.24 KFX94936.1 - 3.3e-82 275.0 58.3 9.2e-43 146.1 31.7 3.3 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFX94936.1 - 2.9e-38 131.5 0.0 4.1e-19 69.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFX94936.1 - 1.1e-26 92.6 11.2 5.1e-25 87.2 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX94936.1 - 4.7e-12 46.4 0.1 1.1e-11 45.1 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KFX94936.1 - 1.2e-06 28.8 0.0 0.00033 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX94936.1 - 1.6e-06 28.7 0.0 0.00022 21.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFX94936.1 - 3.2e-06 27.2 0.0 0.0065 16.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFX94936.1 - 4.3e-06 27.2 0.0 0.0055 17.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX94936.1 - 2e-05 24.5 0.1 0.00059 19.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFX94936.1 - 0.00025 21.1 0.1 0.091 12.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KFX94936.1 - 0.00048 19.8 1.3 0.44 10.3 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KFX94936.1 - 0.00051 20.3 0.0 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFX94936.1 - 0.00074 19.8 0.4 0.0044 17.3 0.1 2.4 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KFX94936.1 - 0.0023 17.5 0.4 0.22 11.1 0.3 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFX94936.1 - 0.0026 17.4 0.1 0.035 13.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFX94936.1 - 0.0031 17.4 0.6 0.6 10.0 0.5 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFX94936.1 - 0.0038 17.0 0.1 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KFX94936.1 - 0.0041 16.6 0.3 0.034 13.6 0.0 2.5 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KFX94936.1 - 0.013 14.9 0.3 6.6 6.0 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KFX94936.1 - 0.028 14.9 0.4 13 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFX94936.1 - 0.067 13.6 0.0 11 6.4 0.1 3.2 3 0 0 3 3 3 0 RNA helicase ATG19_autophagy PF12744.7 KFX94936.1 - 0.069 12.3 3.6 0.094 11.9 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding AAA_17 PF13207.6 KFX94936.1 - 0.074 13.5 1.6 2.4 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KFX94936.1 - 0.093 12.0 0.9 0.54 9.5 0.1 2.2 2 0 0 2 2 2 0 Septin T2SSE PF00437.20 KFX94936.1 - 0.13 11.3 0.1 3.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 KFX94936.1 - 0.18 11.0 1.5 4.4 6.4 0.4 2.3 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KFX94936.1 - 0.2 10.9 0.3 1.9 7.8 0.2 2.2 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KFX94936.1 - 0.4 10.7 3.0 1 9.3 0.4 2.8 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFX94936.1 - 0.44 10.2 4.8 1.8 8.2 0.4 2.9 3 0 0 3 3 3 0 AAA domain SecE PF00584.20 KFX94936.1 - 8.1 6.5 10.6 5.8 6.9 0.1 3.9 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Sugar_tr PF00083.24 KFX94937.1 - 1.3e-119 400.0 21.1 1.5e-119 399.9 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94937.1 - 4.1e-27 95.0 22.4 3.3e-20 72.3 3.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily GMC_oxred_C PF05199.13 KFX94938.1 - 7.2e-29 101.2 0.0 1.2e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFX94938.1 - 2.4e-26 92.8 0.0 3.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KFX94938.1 - 5.3e-05 23.4 1.2 0.00014 22.0 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX94938.1 - 0.00087 18.5 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KFX94938.1 - 0.0032 16.6 0.0 0.0046 16.1 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX94938.1 - 0.031 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX94938.1 - 0.036 13.7 1.0 0.071 12.8 0.7 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KFX94938.1 - 0.063 12.8 0.0 0.54 9.8 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX94938.1 - 0.11 11.2 0.5 0.15 10.7 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFX94938.1 - 0.17 11.1 0.1 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 KFX94939.1 - 2.8e-46 158.1 6.0 3.3e-46 157.8 6.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94939.1 - 7.4e-10 38.8 6.5 1.5e-09 37.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNApol3-delta_C PF09115.10 KFX94939.1 - 0.16 12.5 1.0 0.36 11.3 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Pyr_redox_2 PF07992.14 KFX94940.1 - 7.9e-34 117.2 0.2 9.5e-34 117.0 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX94940.1 - 3.2e-06 27.6 0.3 0.00025 21.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX94940.1 - 0.00059 19.8 0.7 2.8 7.9 0.0 4.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding Phage_spike PF18715.1 KFX94940.1 - 0.087 12.9 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage spike trimer DAO PF01266.24 KFX94940.1 - 0.16 11.5 2.4 4.1 6.9 0.1 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX94940.1 - 0.3 10.1 0.5 7.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Chitin_synth_1 PF01644.17 KFX94941.1 - 1.5e-79 265.7 0.3 3.5e-79 264.5 0.2 1.7 2 0 0 2 2 2 1 Chitin synthase DUF1993 PF09351.10 KFX94941.1 - 4.3e-52 176.5 0.0 8.3e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Chitin_synth_1N PF08407.11 KFX94941.1 - 2e-27 95.0 0.1 4e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFX94941.1 - 3.7e-25 88.5 4.1 2.5e-21 75.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFX94941.1 - 5.4e-09 36.2 1.7 1.6e-08 34.7 1.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF3995 PF13160.6 KFX94941.1 - 0.032 14.6 0.2 0.094 13.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) CD99L2 PF12301.8 KFX94942.1 - 0.029 14.7 0.3 0.029 14.7 0.3 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 Amino_oxidase PF01593.24 KFX94944.1 - 3.3e-81 273.9 0.1 7.7e-68 229.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFX94944.1 - 7.1e-13 48.7 0.1 1.5e-12 47.7 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KFX94944.1 - 9.4e-09 35.6 0.2 2.2e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 KFX94944.1 - 1.3e-06 28.5 0.2 3.1e-06 27.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 KFX94944.1 - 5.7e-06 26.8 0.2 1.1e-05 25.9 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 KFX94944.1 - 0.00063 19.1 0.0 0.0057 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX94944.1 - 0.0047 16.6 0.2 0.0081 15.8 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Senescence_reg PF04520.13 KFX94944.1 - 0.21 12.4 2.8 0.19 12.6 1.2 1.7 2 0 0 2 2 2 0 Senescence regulator Sec1 PF00995.23 KFX94945.1 - 4.7e-119 399.2 0.0 5.7e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.26 KFX94947.1 - 1.6e-14 53.8 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFX94947.1 - 0.027 14.7 0.3 0.074 13.3 0.3 1.7 1 1 0 1 1 1 0 RWD domain Na_Ca_ex PF01699.24 KFX94964.1 - 9.5e-44 149.0 41.8 4.1e-23 82.0 17.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4079 PF13301.6 KFX94964.1 - 0.0021 18.2 0.0 0.0021 18.2 0.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF4079) MFS_1 PF07690.16 KFX94971.1 - 2.9e-32 112.0 60.1 2.2e-29 102.5 40.1 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX94971.1 - 1.2e-10 40.9 9.8 1.2e-10 40.9 9.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFX94971.1 - 0.023 13.0 11.7 0.18 10.0 2.0 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KFX94972.1 - 1.5e-67 228.4 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CMD PF02627.20 KFX94973.1 - 0.14 12.2 0.0 0.82 9.8 0.0 2.2 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family ADH_zinc_N PF00107.26 KFX94974.1 - 7.1e-07 29.3 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX94974.1 - 1.5e-05 24.9 0.0 5.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX94974.1 - 0.013 16.6 0.0 0.037 15.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX94974.1 - 0.022 14.7 0.1 0.071 13.0 0.0 1.9 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase Cupin_3 PF05899.12 KFX94974.1 - 0.2 11.4 0.1 2 8.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AMP-binding PF00501.28 KFX94975.1 - 7.3e-164 545.4 0.0 2.6e-87 293.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KFX94975.1 - 5.5e-62 209.9 0.0 9.3e-30 103.7 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KFX94975.1 - 1.2e-17 64.0 2.1 8.2e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX94975.1 - 5.3e-09 36.9 0.0 1.3e-06 29.3 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BUD22 PF09073.10 KFX94981.1 - 2.1 7.6 35.5 2.3 7.4 35.5 1.0 1 0 0 1 1 1 0 BUD22 XRCC4 PF06632.12 KFX94981.1 - 3.6 6.3 17.8 4.6 6.0 17.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DNA_pol_A_exo1 PF01612.20 KFX94982.1 - 7e-06 25.9 0.0 3.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease Rbx_binding PF18113.1 KFX94985.1 - 0.072 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain PRTP PF01366.18 KFX94987.1 - 2.1 6.3 5.7 0.35 8.9 2.2 1.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Acyl_transf_1 PF00698.21 KFX94988.1 - 7.6e-09 35.5 0.1 2.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Trp_oprn_chp PF09534.10 KFX94995.1 - 0.03 14.1 0.2 0.037 13.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gram_pos_anchor PF00746.21 KFX94995.1 - 0.11 12.4 1.6 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3824 PF12868.7 KFX94995.1 - 0.43 11.2 14.7 0.084 13.5 6.2 2.4 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Pkinase PF00069.25 KFX94996.1 - 6.7e-48 163.3 0.0 3.3e-27 95.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94996.1 - 1.8e-21 76.6 0.0 2.5e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFX94996.1 - 0.0016 18.4 0.4 0.0056 16.6 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.6 KFX94996.1 - 0.028 14.4 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFX94996.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFX94996.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NPL PF17800.1 KFX94997.1 - 1.6e-35 121.8 2.5 1.6e-35 121.8 2.5 2.4 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KFX94997.1 - 3.7e-31 107.3 0.0 1e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.20 KFX94998.1 - 2e-40 138.2 0.0 3.6e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CSTF2_hinge PF14327.6 KFX94998.1 - 4.5e-30 103.9 0.8 4.5e-30 103.9 0.8 2.7 3 0 0 3 3 2 1 Hinge domain of cleavage stimulation factor subunit 2 REV1_C PF16727.5 KFX94998.1 - 3.5e-27 94.6 0.9 6.7e-27 93.7 0.9 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain RRM_1 PF00076.22 KFX94998.1 - 5.5e-22 77.4 0.0 1.5e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBM PF14377.6 KFX94998.1 - 1.3e-15 56.3 11.5 2e-07 30.2 0.3 4.4 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 KFX94998.1 - 6.5e-12 46.2 0.0 1.8e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KFX94998.1 - 1.4e-10 41.4 0.0 6.1e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain CSTF_C PF14304.6 KFX94998.1 - 9.5e-09 34.7 4.3 9.5e-09 34.7 4.3 3.8 5 0 0 5 5 5 1 Transcription termination and cleavage factor C-terminal BRCT PF00533.26 KFX94998.1 - 6.3e-08 32.9 0.0 5e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFX94998.1 - 0.00022 21.1 0.0 0.00061 19.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain mCpol PF18182.1 KFX94998.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 KFX94998.1 - 0.05 14.0 0.2 0.46 10.9 0.0 2.8 2 0 0 2 2 2 0 IMS family HHH motif DUF1805 PF08827.11 KFX94998.1 - 0.086 13.2 0.0 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) NOG1_N PF17835.1 KFX94998.1 - 0.12 12.3 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NOG1 N-terminal helical domain RRM_7 PF16367.5 KFX94998.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Band_7 PF01145.25 KFX94999.1 - 3.6e-21 76.0 3.1 5.7e-21 75.3 3.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 KFX95000.1 - 1.8e-26 91.7 0.2 2e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX95000.1 - 6.6e-14 51.5 0.2 7.2e-14 51.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFX95000.1 - 5.2e-05 23.6 0.1 0.00014 22.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFX95000.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain SnoaL PF07366.12 KFX95001.1 - 0.0034 17.2 0.0 0.007 16.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Elongin_A PF06881.11 KFX95002.1 - 1.1e-30 106.2 2.1 2.3e-30 105.2 1.0 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3333 PF11812.8 KFX95002.1 - 0.25 11.5 2.3 8.8 6.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3333) DUF4219 PF13961.6 KFX95018.1 - 4.5e-13 48.5 0.5 4.5e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 KFX95018.1 - 1e-06 28.5 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KFX95018.1 - 0.036 13.9 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KFX95019.1 - 1.1e-09 37.7 2.4 3.6e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 KFX95019.1 - 2.6e-08 33.6 0.0 0.0053 16.4 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF2408 PF10303.9 KFX95019.1 - 0.024 15.2 0.2 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Retrotran_gag_3 PF14244.6 KFX95019.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ABC_tran_CTD PF16326.5 KFX95019.1 - 0.3 11.4 2.4 11 6.4 0.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain HalX PF08663.10 KFX95019.1 - 5.3 7.4 7.8 31 5.0 0.0 4.1 4 1 1 5 5 5 0 HalX domain Zn_clus PF00172.18 KFX95023.1 - 4.5e-11 42.7 9.8 6.2e-11 42.2 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_N PF01213.19 KFX95023.1 - 2.2 7.7 9.8 2.6 7.4 7.4 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SSP160 PF06933.11 KFX95023.1 - 4.4 5.4 11.6 5 5.2 11.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RSN1_7TM PF02714.15 KFX95047.1 - 6.6e-79 265.1 18.5 1.2e-78 264.2 18.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFX95047.1 - 9.9e-39 133.4 0.0 1.4e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFX95047.1 - 3.8e-36 124.2 1.5 4.4e-36 124.0 0.2 1.9 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport WD40 PF00400.32 KFX95073.1 - 6.5e-16 58.4 8.2 0.0052 17.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX95073.1 - 4.9e-06 26.8 0.3 0.031 14.6 0.1 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX95073.1 - 0.0015 17.3 0.6 0.0073 15.0 0.3 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 HA2 PF04408.23 KFX95074.1 - 1.6e-19 70.1 0.0 1.6e-19 70.1 0.0 2.9 4 0 0 4 4 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX95074.1 - 1.4e-16 60.6 0.0 9.2e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX95074.1 - 2.2e-13 50.5 0.0 5.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX95074.1 - 7.8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFX95074.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFX95074.1 - 0.00074 19.8 0.2 0.0026 18.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX95074.1 - 0.00088 19.0 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX95074.1 - 0.0011 19.4 0.1 0.0026 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFX95074.1 - 0.0031 16.6 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KFX95074.1 - 0.009 16.0 0.0 3.2 7.7 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFX95074.1 - 0.028 14.0 0.2 0.071 12.7 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KFX95074.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 KFX95074.1 - 0.032 14.2 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 KFX95074.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KFX95074.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KFX95074.1 - 0.076 13.5 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.6 KFX95074.1 - 0.084 12.9 0.1 0.42 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX95074.1 - 0.14 12.1 0.3 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KFX95074.1 - 0.17 11.4 0.3 1 9.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFX95074.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain zf-CCCH_2 PF14608.6 KFX95076.1 - 1.9e-13 50.3 56.6 9.7e-07 29.0 12.2 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KFX95076.1 - 0.0041 17.4 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Ubiquitin_2 PF14560.6 KFX95085.1 - 8.2e-21 74.3 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 KFX95085.1 - 1.2e-20 73.2 2.8 1.8e-20 72.7 2.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 KFX95085.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 KFX95085.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain Myb_DNA-binding PF00249.31 KFX95086.1 - 8.5e-14 51.5 4.0 4.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX95086.1 - 7.9e-06 26.0 2.0 0.012 15.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 KFX95087.1 - 1.4e-08 35.3 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX95087.1 - 3.9e-07 30.1 0.0 5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX95087.1 - 5.3e-07 30.3 0.0 8.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX95087.1 - 5.9e-06 26.9 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX95087.1 - 0.0039 17.0 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFX95087.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KFX95087.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 KFX95087.1 - 0.17 11.3 0.0 0.44 9.9 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB UCH PF00443.29 KFX95088.1 - 1.4e-18 67.3 0.0 3.3e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX95088.1 - 5.9e-13 49.1 0.2 6.7e-12 45.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.10 KFX95088.1 - 0.031 14.4 0.3 6.6 6.9 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 KFX95088.1 - 0.069 12.8 1.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GET2 PF08690.10 KFX95088.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Y_phosphatase PF00102.27 KFX95089.1 - 8.2e-58 195.8 0.0 7.5e-57 192.6 0.0 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KFX95089.1 - 1.3e-12 48.2 0.0 4.6e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KFX95089.1 - 0.027 14.4 0.1 0.089 12.7 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFX95089.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.29 KFX95090.1 - 8e-44 149.3 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX95090.1 - 6.5e-14 51.5 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFX95090.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX95090.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFX95090.1 - 2e-06 28.3 0.0 0.00011 22.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KFX95090.1 - 1.7e-05 24.7 2.4 4.5e-05 23.3 2.4 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KFX95090.1 - 2.7e-05 24.5 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFX95090.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX95090.1 - 0.00098 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFX95090.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFX95090.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFX95090.1 - 0.0034 17.9 0.0 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KFX95090.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFX95090.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KFX95090.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFX95090.1 - 0.0095 15.6 0.1 0.036 13.7 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 KFX95090.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFX95090.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX95090.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX95090.1 - 0.022 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFX95090.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFX95090.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KFX95090.1 - 0.034 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KFX95090.1 - 0.035 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX95090.1 - 0.036 14.4 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFX95090.1 - 0.05 13.2 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 KFX95090.1 - 0.052 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 KFX95090.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KFX95090.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 KFX95090.1 - 0.17 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Na_Ca_ex PF01699.24 KFX95091.1 - 2.2e-19 69.9 34.9 1.5e-14 54.2 14.2 4.1 4 2 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KFX95091.1 - 1e-15 58.2 12.9 1e-15 58.2 12.9 4.3 5 0 0 5 5 5 1 Inner membrane component domain OMPdecase PF00215.24 KFX95092.1 - 1.2e-89 299.8 0.1 1.7e-89 299.3 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MR_MLE_C PF13378.6 KFX95093.1 - 6e-58 196.0 0.0 8.8e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFX95093.1 - 0.0019 17.4 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 KFX95093.1 - 0.0025 18.0 0.2 0.0077 16.4 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 KFX95094.1 - 4.1e-37 127.5 0.0 5.2e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family RNA_polI_A34 PF08208.11 KFX95101.1 - 4.4e-20 72.7 10.2 5.3e-20 72.4 10.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Abhydrolase_6 PF12697.7 KFX95102.1 - 0.00054 20.6 9.3 0.00073 20.2 9.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFX95102.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KFX95102.1 - 0.13 11.9 0.3 0.2 11.3 0.3 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold CFEM PF05730.11 KFX95103.1 - 3.8e-13 49.3 9.7 6.5e-13 48.6 9.7 1.4 1 0 0 1 1 1 1 CFEM domain Cnn_1N PF07989.11 KFX95113.1 - 9.7e-06 25.7 14.5 4.2e-05 23.6 14.5 2.1 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 KFX95113.1 - 0.059 13.2 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region UPF0242 PF06785.11 KFX95113.1 - 0.63 10.1 11.5 1.4 9.0 11.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KFX95113.1 - 0.84 10.0 16.3 0.26 11.7 8.3 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 KFX95113.1 - 2.8 7.0 9.2 4.7 6.2 9.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LCE PF14672.6 KFX95113.1 - 4 8.1 7.0 1.2 9.7 2.1 2.7 2 0 0 2 2 2 0 Late cornified envelope Snf7 PF03357.21 KFX95115.1 - 3.9e-44 150.3 11.2 4.6e-44 150.1 11.2 1.1 1 0 0 1 1 1 1 Snf7 Alpha-2-MRAP_C PF06401.11 KFX95115.1 - 0.024 14.6 3.7 0.048 13.6 2.5 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain RE_Bsp6I PF09504.10 KFX95115.1 - 0.024 14.2 0.7 0.059 13.0 0.2 1.8 2 0 0 2 2 2 0 Bsp6I restriction endonuclease NPV_P10 PF05531.12 KFX95115.1 - 0.066 13.7 9.0 1.4 9.5 1.9 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 KFX95115.1 - 0.16 10.6 8.0 0.81 8.2 4.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KFX95115.1 - 2.8 8.4 9.4 5.5 7.5 0.0 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) SAPS PF04499.15 KFX95117.1 - 4.1e-193 642.6 0.7 4.1e-193 642.6 0.7 2.7 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Homeobox_KN PF05920.11 KFX95118.1 - 1.1e-20 73.2 0.1 2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFX95118.1 - 2.8e-08 33.5 0.3 4.1e-08 33.0 0.3 1.2 1 0 0 1 1 1 1 Homeodomain GatB_N PF02934.15 KFX95119.1 - 4.1e-98 328.1 0.0 5.3e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain FKBP_C PF00254.28 KFX95121.1 - 1.8e-26 92.3 0.0 2.2e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHC2_SAM_assoc PF16616.5 KFX95122.1 - 0.33 11.8 16.2 0.038 14.8 4.2 2.9 2 1 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 FMN_dh PF01070.18 KFX95125.1 - 4.6e-101 338.3 0.0 6.5e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFX95125.1 - 5.1e-20 71.4 0.0 1.1e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KFX95125.1 - 2e-06 27.1 0.1 6.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFX95125.1 - 3.6e-06 26.4 0.0 6.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KFX95125.1 - 0.049 12.9 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFX95125.1 - 0.059 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 KFX95125.1 - 0.071 12.5 0.4 0.16 11.3 0.2 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 KFX95125.1 - 0.19 10.9 0.0 0.79 8.9 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.24 KFX95126.1 - 5.1e-92 309.1 24.4 5.8e-92 308.9 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95126.1 - 5.4e-30 104.5 19.5 5.4e-30 104.5 19.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Caps_synth_CapC PF14102.6 KFX95126.1 - 0.018 15.5 8.1 0.03 14.7 2.3 2.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC MFS_1 PF07690.16 KFX95127.1 - 1.2e-36 126.3 28.1 4.5e-36 124.5 28.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX95127.1 - 0.0062 15.9 23.0 3.8 6.7 23.0 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2499 PF10693.9 KFX95127.1 - 1.5 9.2 5.5 0.56 10.5 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2499) FAD_binding_3 PF01494.19 KFX95128.1 - 2.6e-09 36.8 0.0 0.0083 15.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KFX95128.1 - 0.0032 16.7 0.0 0.55 9.4 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX95128.1 - 0.0051 16.4 0.0 0.14 11.7 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX95128.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX95128.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFX95128.1 - 0.17 12.4 0.0 1.4 9.5 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rsm22 PF09243.10 KFX95129.1 - 5.7e-34 117.6 0.0 8.1e-33 113.9 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Golgin_A5 PF09787.9 KFX95129.1 - 0.27 10.7 9.1 0.45 9.9 9.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ribosomal_S14 PF00253.21 KFX95134.1 - 8e-22 76.8 0.5 1.8e-21 75.6 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e adh_short PF00106.25 KFX95135.1 - 1.1e-27 96.8 0.0 2.8e-26 92.2 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95135.1 - 1.3e-18 67.5 0.0 8.6e-17 61.5 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.25 KFX95135.1 - 7.6e-05 22.9 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family KR PF08659.10 KFX95135.1 - 0.00023 21.1 1.3 0.0091 15.9 0.0 3.2 4 0 0 4 4 4 1 KR domain Acetyltransf_10 PF13673.7 KFX95135.1 - 0.0028 17.6 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX95135.1 - 0.0034 17.8 0.0 0.0092 16.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Rpp20 PF12328.8 KFX95136.1 - 1.9e-29 102.4 0.7 2.4e-29 102.0 0.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KFX95136.1 - 1.3e-11 44.2 0.0 2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.9 KFX95137.1 - 5.7e-74 248.9 0.0 7.9e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Thioredoxin PF00085.20 KFX95138.1 - 6.9e-27 93.4 0.0 9.3e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFX95138.1 - 3.3e-07 30.7 0.1 9.9e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFX95138.1 - 2.7e-06 27.6 0.0 0.00062 20.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KFX95138.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFX95138.1 - 0.0001 22.1 0.1 0.19 11.5 0.0 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KFX95138.1 - 0.00045 20.1 0.1 0.016 15.1 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family SelK_SelG PF10961.8 KFX95138.1 - 0.0026 18.3 0.0 0.0055 17.3 0.0 1.6 1 1 0 1 1 1 1 Selenoprotein SelK_SelG HyaE PF07449.11 KFX95138.1 - 0.0052 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFX95138.1 - 0.0053 16.5 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFX95138.1 - 0.032 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 KFX95138.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 KFX95138.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Methyltrn_RNA_3 PF02598.17 KFX95139.1 - 3.1e-71 240.2 0.0 3.6e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase HNH_2 PF13391.6 KFX95140.1 - 1.5e-14 53.9 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF1510 PF07423.11 KFX95140.1 - 0.18 12.0 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) Mannosidase_ig PF17786.1 KFX95141.1 - 9.4e-14 51.8 0.1 2.1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFX95141.1 - 1.1e-06 29.3 0.0 8.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFX95141.1 - 0.00028 20.9 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFX95141.1 - 0.00049 19.3 0.1 0.0049 16.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 KFX95141.1 - 0.0015 18.2 0.0 0.0076 16.0 0.0 2.2 1 0 0 1 1 1 1 Ig-fold domain Ribosomal_L7Ae PF01248.26 KFX95153.1 - 1.9e-21 75.6 1.0 5.8e-21 74.0 1.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AMPK1_CBM PF16561.5 KFX95154.1 - 0.00018 21.7 0.0 0.00037 20.6 0.0 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MF_alpha_N PF05436.11 KFX95155.1 - 0.08 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus SCP2 PF02036.17 KFX95158.1 - 5.5e-24 84.6 1.2 6.3e-24 84.4 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFX95158.1 - 9.6e-08 32.4 0.3 1.3e-07 32.0 0.3 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFX95158.1 - 0.021 15.2 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain EamA PF00892.20 KFX95159.1 - 3.2e-07 30.6 26.8 9e-05 22.7 0.8 2.5 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KFX95159.1 - 1.3e-05 24.4 6.7 6.3e-05 22.1 6.7 2.3 1 1 0 1 1 1 1 Ceramide synthase regulator DUF3619 PF12279.8 KFX95160.1 - 0.041 14.2 2.0 0.08 13.3 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3619) SH3_9 PF14604.6 KFX95166.1 - 0.00014 21.6 0.1 0.00024 20.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX95166.1 - 0.002 17.7 0.1 0.0037 16.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX95166.1 - 0.12 12.0 0.8 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain Glyco_hydro_32N PF00251.20 KFX95168.1 - 1.8e-37 129.5 0.0 3e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFX95168.1 - 3.1e-25 89.0 0.0 4.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 KFX95168.1 - 0.045 13.8 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) Glyco_hydro_43 PF04616.14 KFX95168.1 - 0.14 11.4 0.0 2.5 7.3 0.0 2.5 1 1 2 3 3 3 0 Glycosyl hydrolases family 43 Amidohydro_1 PF01979.20 KFX95171.1 - 2e-19 70.1 0.1 3.2e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX95171.1 - 6.1e-10 39.2 0.1 7.6e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family AA_permease_2 PF13520.6 KFX95172.1 - 2.9e-56 191.1 53.1 3.6e-56 190.8 53.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX95172.1 - 5.3e-16 58.3 48.4 9.6e-16 57.4 48.4 1.3 1 1 0 1 1 1 1 Amino acid permease Med17 PF10156.9 KFX95178.1 - 2e-63 214.7 0.1 2.4e-63 214.5 0.1 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 KFX95179.1 - 5.3e-185 613.3 1.5 4.1e-103 344.6 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.8 KFX95179.1 - 0.069 12.9 0.4 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Glycos_trans_3N PF02885.17 KFX95179.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain tRNA-synt_2 PF00152.20 KFX95179.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Ank_2 PF12796.7 KFX95180.1 - 5.3e-71 235.2 30.0 7.9e-15 55.2 0.2 7.1 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95180.1 - 1.5e-49 165.7 20.2 7.9e-09 35.9 0.1 9.1 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KFX95180.1 - 3.8e-40 134.6 24.8 0.0014 19.0 0.0 11.9 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.6 KFX95180.1 - 1.7e-36 120.1 15.6 0.019 15.5 0.1 13.1 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KFX95180.1 - 4.8e-28 96.9 16.6 0.00045 20.5 0.1 9.9 3 3 8 11 11 11 10 Ankyrin repeats (many copies) NACHT PF05729.12 KFX95180.1 - 4.9e-06 26.6 1.7 4e-05 23.6 0.1 2.4 1 1 1 2 2 2 1 NACHT domain SesA PF17107.5 KFX95180.1 - 0.0034 17.6 0.1 0.17 12.1 0.0 3.5 3 1 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Phage_holin_3_1 PF05106.12 KFX95180.1 - 0.01 16.2 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Helo_like_N PF17111.5 KFX95180.1 - 0.37 10.1 2.4 2 7.7 2.4 2.2 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Pkinase PF00069.25 KFX95183.1 - 2.6e-62 210.6 0.0 9.4e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95183.1 - 3.3e-27 95.4 0.0 8e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KFX95183.1 - 1.5e-12 47.6 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KFX95183.1 - 7.2e-08 32.1 0.1 1.8e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KFX95183.1 - 1.6e-06 28.2 1.3 0.003 17.5 0.1 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFX95183.1 - 0.0066 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFX95183.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 KFX95183.1 - 0.15 12.4 0.0 0.41 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KFX95183.1 - 0.16 11.0 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ubiquitin PF00240.23 KFX95203.1 - 4.6e-168 545.3 27.6 4.7e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KFX95203.1 - 4.3e-79 260.4 28.3 2.9e-15 55.9 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFX95203.1 - 8.3e-28 96.7 14.8 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KFX95203.1 - 5.4e-20 71.1 5.5 0.038 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFX95203.1 - 3.3e-18 65.8 12.2 0.04 14.3 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFX95203.1 - 2.2e-17 63.2 4.7 0.18 12.0 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFX95203.1 - 7e-16 58.7 2.8 0.49 11.0 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 KFX95203.1 - 3.1e-08 33.3 1.3 2.6 7.3 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KFX95203.1 - 9.8e-08 31.9 32.0 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 KFX95203.1 - 2.4e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KFX95203.1 - 5.3e-07 29.7 5.3 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KFX95203.1 - 1.6e-06 27.8 7.7 13 5.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 KFX95203.1 - 2.4e-06 28.2 0.6 71 4.3 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KFX95203.1 - 1.4e-05 25.2 7.4 9.9 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KFX95203.1 - 3e-05 23.6 0.0 32 3.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF493 PF04359.14 KFX95203.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 KFX95203.1 - 0.00041 20.5 9.7 38 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ORF11CD3 PF10549.9 KFX95203.1 - 0.00068 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 KFX95203.1 - 0.0018 18.8 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 KFX95203.1 - 0.024 13.6 0.0 84 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 KFX95203.1 - 0.14 12.3 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 KFX95203.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 KFX95203.1 - 0.23 11.1 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 KFX95203.1 - 0.28 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 KFX95203.1 - 5.6 6.8 13.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 KFX95204.1 - 0.0076 16.4 7.7 0.0076 16.4 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFX95205.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 KFX95205.1 - 0.034 13.7 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KFX95205.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltrans PF00432.21 KFX95206.1 - 7.3e-32 108.8 25.1 1.9e-08 33.9 0.8 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 KFX95207.1 - 0.00018 22.1 0.0 0.00029 21.5 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFX95207.1 - 0.0027 17.9 0.0 0.004 17.4 0.0 1.4 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 CGI-121 PF08617.10 KFX95212.1 - 2.6e-54 183.7 0.0 3.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Staufen_C PF16482.5 KFX95212.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Staufen C-terminal domain CP2 PF04516.15 KFX95213.1 - 1.7e-80 269.6 0.0 2.6e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KFX95213.1 - 0.022 13.5 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Tektin family LPP PF04728.13 KFX95213.1 - 0.18 12.2 0.2 0.44 11.0 0.2 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.8 KFX95213.1 - 0.25 11.3 0.7 0.5 10.4 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PseudoU_synth_2 PF00849.22 KFX95220.1 - 3.1e-25 89.1 0.0 5.2e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 KFX95220.1 - 0.0053 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 KFX95220.1 - 0.035 14.3 0.1 0.087 13.0 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 KFX95220.1 - 0.13 12.0 1.1 0.27 11.0 1.1 1.5 1 0 0 1 1 1 0 S4 domain Cnn_1N PF07989.11 KFX95226.1 - 2.4e-22 78.8 9.3 2.4e-22 78.8 9.3 11.6 7 2 4 12 12 12 2 Centrosomin N-terminal motif 1 adh_short PF00106.25 KFX95226.1 - 0.14 11.6 0.1 1.5 8.2 0.0 2.8 2 0 0 2 2 2 0 short chain dehydrogenase Baculo_PEP_C PF04513.12 KFX95226.1 - 1.3 9.1 32.1 0.74 9.9 2.0 5.9 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4129 PF13559.6 KFX95233.1 - 2.1e-05 24.7 0.2 2.1e-05 24.7 0.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) Yip1 PF04893.17 KFX95233.1 - 0.12 12.1 4.3 0.18 11.5 4.3 1.3 1 0 0 1 1 1 0 Yip1 domain CENP-B_dimeris PF09026.10 KFX95233.1 - 0.27 11.7 5.9 0.57 10.6 5.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NnrU PF07298.11 KFX95233.1 - 1.1 8.7 6.5 0.058 12.9 1.2 1.5 2 0 0 2 2 2 0 NnrU protein DHHC PF01529.20 KFX95233.1 - 5.7 7.0 4.4 8.7 6.5 4.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Peptidase_S10 PF00450.22 KFX95234.1 - 1.3e-85 288.3 0.2 2.6e-85 287.4 0.2 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase NAD_binding_10 PF13460.6 KFX95244.1 - 5.3e-14 52.5 2.3 7.4e-14 52.1 2.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX95244.1 - 4.1e-11 42.8 0.1 1.9e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX95244.1 - 1.8e-05 24.4 0.9 2.6e-05 23.9 0.6 1.5 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 KFX95244.1 - 8.3e-05 22.8 0.4 0.00015 22.0 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KFX95244.1 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KFX95244.1 - 0.0022 17.0 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX95244.1 - 0.0024 17.0 0.2 0.0032 16.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX95244.1 - 0.0051 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KFX95244.1 - 0.0076 16.7 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFX95244.1 - 0.0086 15.2 0.1 0.022 13.9 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KFX95244.1 - 0.0097 15.9 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.23 KFX95244.1 - 0.024 14.7 0.3 0.037 14.1 0.3 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KFX95244.1 - 0.14 12.9 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.12 KFX95244.1 - 0.14 11.3 0.1 4.6 6.3 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Zn_clus PF00172.18 KFX95245.1 - 0.076 13.2 9.8 0.13 12.4 9.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NETI PF14044.6 KFX95245.1 - 0.13 12.1 0.0 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 NETI protein Pollen_allerg_2 PF01620.16 KFX95245.1 - 0.17 12.1 1.2 0.4 10.9 0.7 1.9 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) SnoaL_4 PF13577.6 KFX95246.1 - 5.8e-16 58.8 0.1 6.6e-16 58.6 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain RPAP1_N PF08621.10 KFX95249.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal Aldedh PF00171.22 KFX95252.1 - 5.8e-91 305.3 4.4 6.4e-91 305.2 4.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PUA PF01472.20 KFX95252.1 - 0.011 15.6 0.7 2.1 8.4 0.0 3.0 3 1 0 3 3 3 0 PUA domain AAA_7 PF12775.7 KFX95252.1 - 0.15 11.6 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 KFX95252.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Fungal_trans PF04082.18 KFX95254.1 - 5.5e-17 61.7 0.2 9e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95254.1 - 1.5e-06 28.2 8.6 3.3e-06 27.1 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KFX95257.1 - 3e-15 56.4 0.2 6.4e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KFX95257.1 - 8.1e-13 48.9 0.1 6.9e-12 45.9 0.0 2.2 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KFX95257.1 - 5.8e-08 32.3 1.1 1.1e-07 31.4 1.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain FAD-oxidase_C PF02913.19 KFX95258.1 - 1.3e-64 218.3 0.0 1.8e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFX95258.1 - 3.5e-35 120.8 0.5 5.7e-35 120.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Turandot PF07240.11 KFX95258.1 - 0.07 13.1 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot Proteasome PF00227.26 KFX95259.1 - 2.3e-55 187.1 0.1 3.1e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX95259.1 - 6.1e-13 48.2 0.3 2e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KFX95259.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MAT1-1-2 PF17043.5 KFX95259.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function zf-CHY PF05495.12 KFX95260.1 - 5.8e-13 49.1 15.8 1.1e-12 48.2 15.8 1.5 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 KFX95260.1 - 0.0083 16.2 4.6 0.0083 16.2 4.6 2.7 2 1 1 3 3 3 2 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 KFX95260.1 - 0.042 13.5 1.4 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Cys_rich_KTR PF14205.6 KFX95260.1 - 0.058 13.2 4.7 3.8 7.4 1.4 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR HypA PF01155.19 KFX95260.1 - 0.29 11.2 8.9 0.71 9.9 8.9 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 KFX95260.1 - 0.47 10.7 12.3 0.62 10.3 9.2 2.3 1 1 1 2 2 2 0 LIM domain zf-H2C2_2 PF13465.6 KFX95260.1 - 0.53 10.8 0.3 0.53 10.8 0.3 3.1 3 1 0 3 3 3 0 Zinc-finger double domain C1_4 PF07975.12 KFX95260.1 - 1.7 8.9 13.3 6.6 7.0 10.0 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2 PF00096.26 KFX95260.1 - 5 7.8 11.6 1.8 9.2 0.9 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 KFX95260.1 - 7 6.7 13.3 0.9 9.5 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain ERCC3_RAD25_C PF16203.5 KFX95261.1 - 1.3e-123 411.0 0.1 2.3e-123 410.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFX95261.1 - 7.6e-35 119.8 0.0 1.9e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX95261.1 - 2.5e-16 60.2 0.0 5.7e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX95261.1 - 1.7e-13 50.9 0.1 4.3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFX95261.1 - 2.9e-08 32.8 0.0 3.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KFX95261.1 - 0.0013 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TrkH PF02386.16 KFX95262.1 - 2e-147 491.7 16.1 1.1e-146 489.3 7.1 2.1 2 0 0 2 2 2 2 Cation transport protein Thi4 PF01946.17 KFX95262.1 - 7.8e-115 382.0 0.0 1.3e-114 381.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFX95262.1 - 1.3e-05 24.9 0.1 2.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX95262.1 - 0.00024 21.3 0.3 0.00069 19.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX95262.1 - 0.0004 19.5 0.0 0.0013 17.8 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX95262.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX95262.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFX95262.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX95262.1 - 0.11 11.5 0.9 0.18 10.9 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4266 PF14086.6 KFX95262.1 - 1.9 9.5 4.3 8.8 7.4 4.3 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Asparaginase PF00710.20 KFX95263.1 - 1.6e-57 194.1 0.0 2.5e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFX95263.1 - 2.4e-24 85.7 0.0 4.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KFX95263.1 - 7.6e-12 45.7 1.8 4.8e-06 27.1 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95263.1 - 1.4e-06 28.7 0.0 6.8e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX95263.1 - 2.9e-06 27.4 0.8 6.7e-06 26.3 0.3 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX95263.1 - 1.4e-05 25.1 0.2 0.00083 19.6 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KFX95263.1 - 5.4e-05 23.5 0.0 0.00075 19.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Nramp PF01566.18 KFX95266.1 - 5.9e-55 186.7 13.5 6e-54 183.4 13.5 2.0 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Jagunal PF07086.12 KFX95266.1 - 2.5 8.1 4.8 4.7 7.2 4.8 1.3 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis Ndc1_Nup PF09531.10 KFX95266.1 - 8.8 4.9 9.3 1.4 7.6 5.2 1.7 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup Cellulase PF00150.18 KFX95267.1 - 5.8e-08 32.5 0.1 8.2e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lum_binding PF00677.17 KFX95268.1 - 1.5e-44 149.8 2.6 1.2e-22 79.7 0.4 2.1 2 0 0 2 2 2 2 Lumazine binding domain YabP PF07873.11 KFX95268.1 - 0.1 12.4 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 YabP family PGM_PMM_I PF02878.16 KFX95269.1 - 3.3e-18 65.7 0.1 6.1e-09 35.7 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFX95269.1 - 8.1e-14 51.6 1.2 2.4e-13 50.1 1.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFX95269.1 - 0.00035 20.7 0.1 0.0012 19.0 0.1 2.0 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFX95269.1 - 0.0032 18.0 0.3 0.032 14.9 0.3 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ERCC4 PF02732.15 KFX95270.1 - 6.9e-25 88.1 0.1 1.1e-24 87.4 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KFX95270.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Spo0M PF07070.11 KFX95270.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein Ank_2 PF12796.7 KFX95275.1 - 9.1e-50 167.2 1.2 8e-15 55.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95275.1 - 1.7e-30 105.0 3.6 5.9e-09 36.3 0.1 5.2 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX95275.1 - 7.6e-27 90.4 0.0 0.0022 18.3 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KFX95275.1 - 1.8e-25 88.2 5.4 0.00034 20.9 0.1 6.8 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFX95275.1 - 4.4e-23 81.1 2.3 4.2e-06 26.9 0.1 6.6 1 1 6 7 7 7 6 Ankyrin repeats (many copies) UDPG_MGDP_dh_C PF03720.15 KFX95275.1 - 0.097 13.1 0.3 61 4.1 0.1 3.9 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain MFS_1 PF07690.16 KFX95292.1 - 1.8e-24 86.4 39.0 3.1e-24 85.6 39.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX95292.1 - 4.4e-05 23.0 27.9 8e-05 22.1 27.9 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Peptidase_C48 PF02902.19 KFX95294.1 - 0.00029 20.7 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_3 PF13302.7 KFX95295.1 - 3.9e-13 50.3 0.0 4.4e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX95295.1 - 5.6e-09 36.2 0.0 7.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KFX95295.1 - 0.0042 17.2 0.0 0.006 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFX95295.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX95295.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.22 KFX95296.1 - 8.1e-74 249.5 0.7 1.2e-73 248.9 0.7 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Sulfatase PF00884.23 KFX95297.1 - 2.3e-77 260.5 0.0 2.9e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFX95297.1 - 0.00012 20.8 0.0 0.0014 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KFX95297.1 - 0.0038 16.9 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KFX95297.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KFX95297.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFX95297.1 - 0.17 12.6 0.7 2.5 8.9 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.24 KFX95298.1 - 3.4e-115 385.5 27.5 3.9e-115 385.3 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95298.1 - 1.8e-18 66.6 33.1 1.5e-17 63.6 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX95298.1 - 4.1e-07 28.9 28.2 2.4e-05 23.1 7.8 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.16 KFX95298.1 - 3.2 7.4 15.9 1.1 9.0 1.4 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Rib_5-P_isom_A PF06026.14 KFX95299.1 - 2e-44 151.3 0.0 1.8e-43 148.1 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Zn_clus PF00172.18 KFX95300.1 - 6.5e-20 71.0 24.4 2.2e-10 40.5 9.3 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX95300.1 - 8.5e-07 28.3 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alginate_lyase2 PF08787.11 KFX95301.1 - 4.7e-50 170.6 0.0 5.3e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 KFX95301.1 - 0.00031 20.7 0.1 0.00084 19.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase Abhydrolase_3 PF07859.13 KFX95302.1 - 4.4e-34 118.2 0.0 6.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFX95302.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase COesterase PF00135.28 KFX95302.1 - 9.1e-05 21.5 0.7 0.00092 18.2 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KFX95302.1 - 0.00079 20.1 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFX95302.1 - 0.022 13.6 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 KFX95302.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.8 KFX95302.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase_phd PF10503.9 KFX95302.1 - 0.27 10.7 1.0 3 7.3 0.1 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase RTA1 PF04479.13 KFX95303.1 - 1.4e-67 227.3 12.1 2e-67 226.8 12.1 1.2 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 KFX95303.1 - 0.65 9.6 5.3 3.6 7.2 1.0 2.8 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF3112 PF11309.8 KFX95303.1 - 0.99 8.8 3.6 1.1 8.6 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3112) Thioesterase PF00975.20 KFX95304.1 - 1.1e-11 45.4 0.1 1.9e-11 44.6 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFX95304.1 - 3.3e-06 27.9 1.0 3.9e-06 27.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX95304.1 - 0.00046 19.9 0.1 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KFX95304.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.16 KFX95305.1 - 2.4e-35 122.1 79.6 1.7e-28 99.5 52.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX95305.1 - 0.74 8.6 27.1 0.68 8.7 6.0 2.4 1 1 1 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 KFX95306.1 - 2.6e-14 52.9 0.2 4.4e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNB PF00773.19 KFX95306.1 - 0.033 13.5 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 RNB domain RRS1 PF04939.12 KFX95306.1 - 0.042 13.7 0.3 0.077 12.9 0.3 1.3 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) COesterase PF00135.28 KFX95308.1 - 1.6e-08 33.9 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ThrE_2 PF12821.7 KFX95308.1 - 0.037 14.2 0.1 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE GMC_oxred_N PF00732.19 KFX95309.1 - 1.5e-61 208.3 0.0 2.5e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase COesterase PF00135.28 KFX95309.1 - 4.4e-56 190.8 0.1 7.5e-56 190.0 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family GMC_oxred_C PF05199.13 KFX95309.1 - 8.1e-30 104.2 0.3 1.6e-29 103.2 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.13 KFX95309.1 - 2.8e-13 50.2 0.5 1.3e-12 48.1 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.7 KFX95309.1 - 1.6e-09 37.5 0.1 3.5e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX95309.1 - 6e-09 35.6 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_S9 PF00326.21 KFX95309.1 - 0.0015 18.1 0.1 0.0072 15.8 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family NAD_binding_8 PF13450.6 KFX95309.1 - 0.0079 16.4 0.3 0.032 14.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain F-box_4 PF15966.5 KFX95309.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 F-box DAO PF01266.24 KFX95309.1 - 0.022 14.3 0.0 0.076 12.6 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFX95309.1 - 0.079 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HSP20 PF00011.21 KFX95310.1 - 1.6e-17 63.5 0.0 1.5e-12 47.6 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFX95310.1 - 0.1 12.2 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 HSP20-like domain found in ArsA MFS_1 PF07690.16 KFX95311.1 - 1.3e-05 24.3 31.3 0.00015 20.8 28.5 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily OST3_OST6 PF04756.13 KFX95311.1 - 0.035 13.5 1.1 0.1 11.9 1.1 1.8 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family CxC3 PF18804.1 KFX95312.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases SNF5 PF04855.12 KFX95322.1 - 1.4e-62 211.6 0.0 4.3e-61 206.7 0.0 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 KFX95323.1 - 3.2e-06 27.0 0.0 4.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Imm26 PF15428.6 KFX95323.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 26 TIP41 PF04176.13 KFX95324.1 - 4.7e-67 224.8 0.1 6.3e-67 224.4 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KFX95325.1 - 2.2e-73 246.9 0.0 2.7e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95325.1 - 1.8e-42 145.4 0.0 2.4e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX95325.1 - 9.4e-07 28.4 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFX95325.1 - 0.0015 17.9 0.2 0.0025 17.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX95325.1 - 0.0088 15.7 0.0 0.071 12.7 0.0 2.0 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KFX95325.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KFX95325.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFX95325.1 - 0.073 12.7 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFX95325.1 - 0.097 11.4 0.1 0.12 11.1 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 KFX95326.1 - 3e-72 241.9 2.0 3.9e-72 241.6 2.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 KFX95326.1 - 0.018 15.4 1.4 0.023 15.0 0.6 1.9 1 1 0 1 1 1 0 Effector protein Tox-MPTase2 PF15638.6 KFX95326.1 - 0.024 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 SprT-like PF10263.9 KFX95326.1 - 0.041 13.8 2.5 0.056 13.3 1.0 1.9 1 1 1 2 2 2 0 SprT-like family DUF2268 PF10026.9 KFX95326.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) zf-CW PF07496.15 KFX95326.1 - 0.14 12.2 4.3 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 CW-type Zinc Finger AA_kinase PF00696.28 KFX95327.1 - 2.1e-40 138.9 2.3 2.7e-40 138.5 2.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFX95327.1 - 1.6e-13 50.4 2.2 8.9e-08 32.0 0.2 2.8 3 0 0 3 3 3 2 PUA domain VIT1 PF01988.19 KFX95333.1 - 1.6e-28 100.1 0.9 2.2e-28 99.6 0.9 1.2 1 0 0 1 1 1 1 VIT family PVL_ORF50 PF07768.11 KFX95334.1 - 0.053 13.8 1.2 0.12 12.7 0.3 2.0 2 0 0 2 2 2 0 PVL ORF-50-like family Myc_target_1 PF15179.6 KFX95334.1 - 2.9 7.8 6.6 0.29 11.0 0.3 2.5 2 2 0 2 2 2 0 Myc target protein 1 IU_nuc_hydro PF01156.19 KFX95336.1 - 3.1e-59 201.0 0.0 5.8e-59 200.2 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 KFX95337.1 - 0.00018 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Rhomboid PF01694.22 KFX95338.1 - 1.8e-18 67.0 6.1 4.1e-18 65.8 6.1 1.5 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.10 KFX95338.1 - 7.7e-05 21.9 1.1 0.022 13.8 0.0 3.4 3 1 0 3 3 3 2 PhoD-like phosphatase AAA PF00004.29 KFX95340.1 - 1.1e-42 145.6 0.0 2e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFX95340.1 - 4.3e-08 33.1 0.0 6.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX95340.1 - 7.6e-06 26.4 0.0 4.2e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFX95340.1 - 1.7e-05 24.9 0.1 0.00018 21.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KFX95340.1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KFX95340.1 - 5.3e-05 23.4 0.0 0.00017 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFX95340.1 - 0.00021 21.6 0.3 0.013 15.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 KFX95340.1 - 0.00021 20.9 0.2 0.45 10.1 0.0 2.7 1 1 0 2 2 2 2 AAA domain ATPase PF06745.13 KFX95340.1 - 0.00038 19.9 0.1 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 KFX95340.1 - 0.00053 20.0 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFX95340.1 - 0.0012 18.6 0.0 0.0039 16.9 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 KFX95340.1 - 0.0018 18.4 0.0 0.0067 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX95340.1 - 0.002 18.5 0.0 0.0071 16.7 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.6 KFX95340.1 - 0.002 18.3 0.1 0.0048 17.0 0.0 1.6 2 0 0 2 2 1 1 Cytidylate kinase-like family TniB PF05621.11 KFX95340.1 - 0.0021 17.5 0.1 0.08 12.3 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 KFX95340.1 - 0.0021 17.3 0.2 0.0048 16.1 0.2 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KFX95340.1 - 0.0023 17.5 0.0 0.0065 16.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 KFX95340.1 - 0.003 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KFX95340.1 - 0.0059 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFX95340.1 - 0.0061 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFX95340.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFX95340.1 - 0.014 15.3 0.0 0.055 13.4 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KFX95340.1 - 0.015 15.8 0.8 0.6 10.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFX95340.1 - 0.037 14.6 0.0 0.091 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KFX95340.1 - 0.045 12.7 0.0 0.086 11.7 0.0 1.4 1 1 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFX95340.1 - 0.048 12.9 0.0 0.15 11.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KFX95340.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Disulph_isomer PF06491.11 KFX95340.1 - 0.09 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Disulphide isomerase Apc15p PF05841.11 KFX95340.1 - 0.78 10.6 2.7 3.5 8.5 2.7 2.0 1 1 0 1 1 1 0 Apc15p protein Snf7 PF03357.21 KFX95341.1 - 6e-33 113.9 10.5 7.5e-33 113.5 10.5 1.2 1 0 0 1 1 1 1 Snf7 YlqD PF11068.8 KFX95341.1 - 0.96 9.8 10.2 6 7.2 2.5 2.4 2 1 0 2 2 2 0 YlqD protein Cytochrom_C PF00034.21 KFX95342.1 - 1.3e-11 45.4 0.0 1.8e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFX95342.1 - 1.1e-08 35.2 0.4 5.7e-08 33.0 0.4 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFX95342.1 - 0.00041 20.1 0.2 0.0027 17.4 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Zn_clus PF00172.18 KFX95357.1 - 1.1e-06 28.6 8.5 2.3e-06 27.6 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 KFX95362.1 - 3.2e-08 32.9 0.0 3.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V UDPGP PF01704.18 KFX95369.1 - 9.7e-54 182.6 0.0 1.5e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase APH PF01636.23 KFX95369.1 - 3.3e-10 40.3 0.0 1.2e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX95369.1 - 0.22 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase adh_short_C2 PF13561.6 KFX95370.1 - 2.2e-13 50.3 0.0 2.3e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX95370.1 - 4.1e-13 49.2 0.0 4.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Condensation PF00668.20 KFX95387.1 - 8.3e-36 123.6 0.0 1.4e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFX95387.1 - 2.9e-13 50.0 0.0 4.2e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.28 KFX95387.1 - 0.081 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme LIM PF00412.22 KFX95392.1 - 1.1e-14 54.3 19.6 1.6e-09 37.9 3.9 2.3 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 KFX95392.1 - 0.0011 18.9 15.6 0.097 12.7 1.4 3.7 1 1 1 2 2 2 2 Double zinc ribbon DUF2175 PF09943.9 KFX95392.1 - 0.012 15.9 7.7 0.67 10.3 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) Cytochrom_CIII PF02085.16 KFX95392.1 - 0.53 10.7 12.6 8.1 6.9 7.7 2.5 1 1 1 2 2 2 0 Class III cytochrome C family Zn-ribbon_8 PF09723.10 KFX95392.1 - 0.57 10.3 21.1 0.38 10.9 1.2 4.1 3 1 1 4 4 4 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFX95392.1 - 1.1 8.8 17.5 3.3 7.3 0.3 4.4 3 1 0 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KFX95392.1 - 2.1 7.8 16.2 3.1 7.3 2.5 5.2 5 1 0 5 5 5 0 zinc-ribbon domain Cytochrom_c3_2 PF14537.6 KFX95392.1 - 4.3 7.9 17.5 21 5.7 8.5 3.2 1 1 2 3 3 3 0 Cytochrome c3 RNHCP PF12647.7 KFX95392.1 - 4.5 7.3 14.0 14 5.7 0.7 3.5 2 1 1 3 3 3 0 RNHCP domain C1_4 PF07975.12 KFX95392.1 - 9.2 6.6 16.3 12 6.3 4.6 3.5 3 0 0 3 3 3 0 TFIIH C1-like domain Cys_Met_Meta_PP PF01053.20 KFX95403.1 - 6.6e-149 495.6 0.0 7.6e-149 495.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX95403.1 - 1.5e-11 44.1 0.1 2.8e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFX95403.1 - 4.4e-09 36.1 0.3 8.5e-09 35.2 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KFX95403.1 - 2.4e-07 30.0 0.2 5.8e-07 28.8 0.2 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX95403.1 - 0.0016 17.7 0.0 0.0036 16.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KFX95403.1 - 0.0081 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 KFX95403.1 - 0.011 14.3 0.3 0.016 13.8 0.3 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase Asparaginase_C PF17763.1 KFX95403.1 - 0.012 15.8 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain MccV PF17508.2 KFX95403.1 - 0.87 10.2 5.3 0.67 10.5 0.2 2.7 3 0 0 3 3 3 0 Microcin V bacteriocin Phage_NinH PF06322.11 KFX95405.1 - 0.11 12.4 1.1 0.19 11.7 0.3 1.7 2 0 0 2 2 2 0 Phage NinH protein Thioredoxin_7 PF13899.6 KFX95406.1 - 1.3e-18 67.0 0.1 2.9e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KFX95406.1 - 4.3e-12 45.6 0.0 9.7e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFX95406.1 - 2.5e-06 27.6 0.0 5.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain DARPP-32 PF05395.12 KFX95406.1 - 0.0068 16.7 6.3 0.0068 16.7 6.3 2.0 2 1 0 2 2 2 1 Protein phosphatase inhibitor 1/DARPP-32 Thioredoxin_2 PF13098.6 KFX95406.1 - 0.0098 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 KFX95406.1 - 0.027 14.4 0.1 0.049 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 PepSY_TM PF03929.16 KFX95406.1 - 0.36 10.5 0.0 0.36 10.5 0.0 2.2 2 1 0 3 3 3 0 PepSY-associated TM region Ecm29 PF13001.7 KFX95407.1 - 3.8e-163 543.7 0.0 4.6e-162 540.2 0.0 2.6 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.22 KFX95407.1 - 3.7e-06 26.7 4.0 7.9 7.0 0.0 8.0 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 KFX95407.1 - 0.00012 22.5 10.5 0.75 10.4 0.1 8.6 8 2 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 KFX95407.1 - 0.0016 18.8 11.8 0.72 10.3 0.1 8.1 8 1 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX95407.1 - 0.002 18.7 0.0 0.35 11.5 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 KFX95407.1 - 0.046 13.9 0.5 13 5.8 0.0 3.7 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair HD_assoc PF13286.6 KFX95407.1 - 0.086 13.4 0.0 32 5.1 0.0 3.9 3 0 0 3 3 3 0 Phosphohydrolase-associated domain IFRD PF05004.13 KFX95407.1 - 1.5 7.9 11.8 6.3 5.8 0.0 5.0 5 1 1 6 6 6 0 Interferon-related developmental regulator (IFRD) MBOAT_2 PF13813.6 KFX95408.1 - 1e-14 54.6 3.6 1e-14 54.6 3.6 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family hDGE_amylase PF14701.6 KFX95409.1 - 2.9e-179 596.8 0.0 3.7e-179 596.4 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFX95409.1 - 1.9e-118 395.7 0.0 2.9e-118 395.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFX95409.1 - 1.9e-85 286.6 0.0 3.3e-85 285.8 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFX95409.1 - 2.4e-28 98.1 0.0 6e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFX95409.1 - 0.00036 20.2 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DAHP_synth_1 PF00793.20 KFX95411.1 - 2.1e-102 341.7 0.0 2.9e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Autophagy_act_C PF03987.15 KFX95412.1 - 3.6e-13 49.9 0.9 6e-13 49.2 0.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Cytochrom_C1 PF02167.15 KFX95413.1 - 4.9e-94 314.1 0.0 6.4e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFX95413.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1515 PF07439.11 KFX95413.1 - 0.14 12.2 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HhH-GPD PF00730.25 KFX95414.1 - 0.00086 19.7 0.0 0.0023 18.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AIG2_2 PF13772.6 KFX95415.1 - 6.1e-05 23.3 0.2 0.00034 20.9 0.2 2.1 1 1 0 1 1 1 1 AIG2-like family FCH PF00611.23 KFX95416.1 - 0.017 15.4 0.5 0.049 13.9 0.5 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4515 PF14988.6 KFX95416.1 - 0.061 13.2 2.2 0.16 11.8 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Taxilin PF09728.9 KFX95416.1 - 0.1 11.7 4.7 1.1 8.4 3.1 2.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein SLX9 PF15341.6 KFX95417.1 - 1.1e-39 135.9 4.4 1.5e-39 135.4 4.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 AP_endonuc_2 PF01261.24 KFX95418.1 - 7.2e-30 104.0 0.0 9.5e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PBSX_XtrA PF17356.2 KFX95419.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Spore_YabQ PF09578.10 KFX95419.1 - 0.075 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) LapA_dom PF06305.11 KFX95419.1 - 0.079 12.8 0.1 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 KFX95420.1 - 6.5e-42 143.2 0.4 9.4e-42 142.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95420.1 - 4e-29 101.8 0.1 4.9e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFX95420.1 - 0.00012 21.6 0.0 0.013 14.9 0.1 2.2 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) ApbA PF02558.16 KFX95420.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cation_efflux PF01545.21 KFX95421.1 - 9.7e-22 77.7 10.7 1.2e-21 77.4 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFX95421.1 - 8.1e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Peptidase_C48 PF02902.19 KFX95422.1 - 5.3e-16 59.1 0.1 2.4e-15 57.0 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KFX95422.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) KH_8 PF17903.1 KFX95423.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFX95423.1 - 0.036 13.9 1.0 0.084 12.7 1.0 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 KFX95424.1 - 1.7e-253 842.1 0.1 2.1e-253 841.8 0.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PsaX PF08078.12 KFX95424.1 - 0.11 12.5 1.0 0.27 11.2 1.0 1.6 1 0 0 1 1 1 0 PsaX family Pkinase PF00069.25 KFX95425.1 - 6.2e-74 248.7 0.0 1.3e-73 247.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95425.1 - 1.7e-36 125.9 0.0 2.5e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFX95425.1 - 3.4e-17 62.5 0.1 7.4e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFX95425.1 - 5.5e-08 32.5 0.0 2.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFX95425.1 - 3.1e-06 26.2 0.0 5.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KFX95425.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KFX95425.1 - 0.015 14.7 0.2 0.028 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFX95425.1 - 0.028 13.4 0.3 0.058 12.4 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KFX95425.1 - 0.067 13.1 0.1 0.23 11.3 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2961 PF11175.8 KFX95425.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) YrbL-PhoP_reg PF10707.9 KFX95425.1 - 0.12 11.9 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KFX95425.1 - 0.24 11.0 0.6 0.62 9.6 0.3 1.7 1 1 1 2 2 2 0 RIO1 family HCNGP PF07818.13 KFX95426.1 - 3.6e-35 120.5 1.2 6.6e-35 119.6 1.2 1.4 1 0 0 1 1 1 1 HCNGP-like protein GRP PF07172.11 KFX95433.1 - 0.02 15.6 7.6 0.02 15.6 7.6 3.9 3 1 0 3 3 3 0 Glycine rich protein family TFIIA PF03153.13 KFX95433.1 - 0.49 10.3 25.6 0.068 13.2 13.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EMG1 PF03587.14 KFX95435.1 - 1.3e-78 263.2 0.0 1.5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase APG9 PF04109.16 KFX95437.1 - 7.6e-208 691.3 10.9 8.9e-208 691.1 10.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF4153 PF13687.6 KFX95437.1 - 1.2 8.7 11.8 0.036 13.7 1.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4153) W2 PF02020.18 KFX95438.1 - 1.8e-19 69.7 1.3 5e-19 68.2 1.3 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFX95438.1 - 2.9e-06 26.8 13.3 0.0057 16.3 3.6 4.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KFX95438.1 - 8.8e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KFX95438.1 - 0.00017 19.9 2.9 0.00031 19.0 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KFX95438.1 - 0.0071 15.3 1.2 0.037 13.0 1.3 1.9 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KFX95438.1 - 0.0073 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFX95438.1 - 0.045 13.5 9.4 0.65 9.8 0.6 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Mito_carr PF00153.27 KFX95439.1 - 3.3e-52 174.4 1.2 4.5e-21 74.6 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein EI24 PF07264.11 KFX95442.1 - 5.9e-10 39.7 18.0 5.9e-10 39.7 18.0 1.6 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Yippee-Mis18 PF03226.14 KFX95445.1 - 1.2e-21 76.9 0.0 2.2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Aldedh PF00171.22 KFX95447.1 - 8.5e-76 255.3 0.0 1e-75 255.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lyase_1 PF00206.20 KFX95448.1 - 4.1e-86 289.2 0.0 5.7e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KFX95448.1 - 1.1e-21 77.4 0.1 2.4e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SPO22 PF08631.10 KFX95448.1 - 0.024 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like FMN_red PF03358.15 KFX95449.1 - 1.6e-30 105.9 0.0 2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX95449.1 - 1.4e-10 41.2 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MRP-S28 PF10213.9 KFX95451.1 - 4.3e-46 156.5 0.1 8.4e-46 155.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Rot1 PF10681.9 KFX95457.1 - 1.3e-28 100.0 1.4 1.5e-28 99.8 1.4 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal PALP PF00291.25 KFX95459.1 - 1.8e-64 218.0 0.2 2.4e-64 217.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LPMO_10 PF03067.15 KFX95460.1 - 4.2e-10 40.6 0.2 6.7e-10 39.9 0.2 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading p450 PF00067.22 KFX95463.1 - 1.2e-59 202.3 0.0 1.5e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PUF PF00806.19 KFX95464.1 - 1.1e-56 185.4 11.7 8.7e-08 31.4 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RNA_pol_Rpb2_6 PF00562.28 KFX95466.1 - 1.9e-120 402.5 0.1 3.6e-120 401.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFX95466.1 - 4.2e-53 179.9 0.1 6.5e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KFX95466.1 - 7.1e-31 106.5 0.8 2.2e-30 104.9 0.8 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KFX95466.1 - 2.4e-29 102.3 0.0 9e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFX95466.1 - 3.1e-22 78.6 0.0 7.1e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFX95466.1 - 2.8e-19 69.1 0.0 5.6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFX95466.1 - 6.5e-10 39.4 1.5 2.5e-09 37.5 1.5 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zn-ribbon_14 PF16503.5 KFX95466.1 - 4.2 7.0 5.7 0.44 10.1 1.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon Sugar_tr PF00083.24 KFX95467.1 - 1.2e-90 304.6 26.4 1.4e-90 304.3 26.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95467.1 - 2.5e-14 53.0 47.4 3.7e-09 36.0 13.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KFX95468.1 - 8e-18 65.8 0.0 9.1e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sua5_yciO_yrdC PF01300.18 KFX95469.1 - 1.8e-14 53.6 0.0 2.9e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 Telomere recombination LysM PF01476.20 KFX95471.1 - 1.9e-20 72.6 0.2 0.0073 16.4 0.0 5.6 5 0 0 5 5 5 5 LysM domain Glyco_hydro_18 PF00704.28 KFX95472.1 - 5.1e-67 226.8 0.0 6e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX95472.1 - 2e-09 37.8 9.8 2e-09 37.8 9.8 3.2 2 1 0 2 2 2 1 Chitin recognition protein Fungal_lectin_2 PF18647.1 KFX95473.1 - 5.1e-38 129.6 0.9 1.3e-37 128.3 0.9 1.8 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KFX95473.1 - 1.9e-10 41.5 4.1 9.7e-10 39.1 3.3 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX95473.1 - 2.4e-06 27.7 0.1 7.2e-06 26.1 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase IpaB_EvcA PF03278.13 KFX95473.1 - 0.00058 19.6 1.4 0.12 12.1 0.1 3.0 2 1 1 3 3 3 2 IpaB/EvcA family MCR_alpha PF02249.17 KFX95473.1 - 0.01 16.3 0.6 2.4 8.6 0.2 2.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain FGGY_C PF02782.16 KFX95478.1 - 4.8e-69 232.1 2.5 7.9e-69 231.4 2.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX95478.1 - 3.9e-65 219.8 0.0 5.5e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_7 PF00840.20 KFX95479.1 - 1e-123 413.3 5.4 1.3e-123 413.0 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Melibiase_2 PF16499.5 KFX95480.1 - 8.2e-56 189.2 4.2 1.3e-39 136.1 0.8 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KFX95480.1 - 1.4e-10 41.1 1.0 2e-09 37.4 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX95480.1 - 1.4e-07 30.8 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 KFX95480.1 - 0.015 13.1 0.1 0.021 12.7 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_26 PF02156.15 KFX95481.1 - 3.2e-74 250.2 2.8 3.8e-74 249.9 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Ank_2 PF12796.7 KFX95482.1 - 8.5e-38 128.8 0.2 4.3e-14 52.9 0.0 5.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX95482.1 - 4e-28 94.4 2.9 0.00017 21.7 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFX95482.1 - 1.2e-25 89.2 4.1 4e-06 27.0 0.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX95482.1 - 3e-25 88.2 0.7 1.1e-07 32.3 0.0 5.4 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX95482.1 - 2e-20 72.3 5.7 0.0034 17.8 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat adh_short PF00106.25 KFX95483.1 - 4.2e-31 107.9 0.0 5.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95483.1 - 1.6e-17 63.8 0.0 3.7e-17 62.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX95483.1 - 2.3e-09 37.4 0.0 3.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX95483.1 - 1.6e-05 24.2 0.0 1.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX95483.1 - 0.00022 20.7 0.0 0.0022 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX95483.1 - 0.0046 16.4 0.0 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KFX95483.1 - 0.039 13.9 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Phytase PF02333.15 KFX95485.1 - 4.7e-63 213.4 3.0 4.3e-61 207.0 0.0 2.4 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KFX95485.1 - 1.4e-07 31.8 31.6 0.0015 18.9 9.4 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 KFX95485.1 - 0.0048 17.2 24.3 0.0051 17.1 5.9 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFX95485.1 - 0.034 14.8 5.7 0.034 14.8 5.7 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF Abhydrolase_3 PF07859.13 KFX95487.1 - 8.1e-31 107.5 0.0 2e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioredoxin PF00085.20 KFX95487.1 - 6.8e-20 71.0 0.0 1.6e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin DLH PF01738.18 KFX95487.1 - 1.4e-08 34.5 0.0 0.0021 17.6 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Acetyltransf_4 PF13420.7 KFX95487.1 - 1.2e-06 28.7 0.0 0.34 11.0 0.0 3.9 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Thioredoxin_2 PF13098.6 KFX95487.1 - 5.5e-05 23.6 0.2 0.00044 20.7 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Acetyltransf_7 PF13508.7 KFX95487.1 - 0.00051 20.4 0.0 0.0027 18.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Thioredoxin_8 PF13905.6 KFX95487.1 - 0.0019 18.5 0.1 0.0059 16.9 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Acetyltransf_1 PF00583.25 KFX95487.1 - 0.0031 17.7 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family BAAT_C PF08840.11 KFX95487.1 - 0.0048 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KFX95487.1 - 0.016 14.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acetyltransf_10 PF13673.7 KFX95487.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.8 2 0 0 2 2 1 0 Acetyltransferase (GNAT) domain Redoxin PF08534.10 KFX95487.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Redoxin DUF2974 PF11187.8 KFX95487.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) OST3_OST6 PF04756.13 KFX95487.1 - 0.083 12.2 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFX95487.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family tRNA-synt_1 PF00133.22 KFX95488.1 - 3.4e-219 729.1 0.1 4.8e-219 728.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX95488.1 - 9.9e-27 93.8 0.0 2.4e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX95488.1 - 9.2e-16 57.6 0.0 1.3e-05 24.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) But2 PF09792.9 KFX95489.1 - 3.4e-60 202.5 3.6 5e-60 202.0 2.0 1.9 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Peptidase_A4 PF01828.17 KFX95489.1 - 0.007 15.9 0.5 0.012 15.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase A4 family CAP_N PF01213.19 KFX95489.1 - 0.29 10.6 1.6 0.53 9.7 1.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PTPRCAP PF15713.5 KFX95490.1 - 1.1 9.5 17.6 2.1 8.6 17.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 KFX95490.1 - 1.5 8.3 17.6 2.5 7.6 17.6 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KFX95490.1 - 1.9 6.6 23.5 2.2 6.4 23.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KFX95490.1 - 2.2 6.5 14.5 2.7 6.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GFO_IDH_MocA PF01408.22 KFX95494.1 - 2.9e-22 79.8 0.1 7.8e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX95494.1 - 5.8e-06 26.3 0.0 4.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX95494.1 - 0.00094 19.8 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 KFX95494.1 - 0.15 12.2 0.0 0.77 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 KFX95496.1 - 0.11 11.4 48.0 0.049 12.5 4.8 4.3 3 1 1 4 4 4 0 Spc7 kinetochore protein Spc29 PF17082.5 KFX95496.1 - 0.2 11.5 17.4 2.7 7.8 5.3 4.1 2 2 2 4 4 4 0 Spindle Pole Component 29 IF-2B PF01008.17 KFX95496.1 - 0.59 9.3 8.9 2.3 7.4 3.6 2.8 2 1 0 2 2 2 0 Initiation factor 2 subunit family ACTH_assoc PF16102.5 KFX95496.1 - 0.68 10.8 3.4 3.4 8.6 0.1 3.5 2 0 0 2 2 2 0 ACTH-associated domain DUF1664 PF07889.12 KFX95496.1 - 3.5 7.7 25.6 0.024 14.7 2.6 5.2 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) BSP_II PF05432.11 KFX95497.1 - 0.37 10.4 9.4 0.4 10.3 9.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hid1 PF12722.7 KFX95499.1 - 1.3 7.1 5.2 1.7 6.7 5.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Golgin_A5 PF09787.9 KFX95499.1 - 1.4 8.3 17.4 2.4 7.5 17.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1690 PF07956.11 KFX95499.1 - 5.3 7.5 26.6 0.091 13.2 13.3 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Polyketide_cyc PF03364.20 KFX95500.1 - 1.3e-23 83.6 0.0 3.9e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFX95500.1 - 0.0048 17.2 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.12 KFX95501.1 - 8.8e-16 58.5 0.0 2.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX95501.1 - 1.3e-15 57.9 0.0 2.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95501.1 - 2.3e-12 47.4 0.0 4.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX95501.1 - 9.5e-12 45.1 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX95501.1 - 2.2e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX95501.1 - 3.6e-08 33.0 0.0 5.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFX95501.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KFX95501.1 - 0.0046 18.0 0.0 0.0097 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX95501.1 - 0.0082 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFX95501.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 KFX95501.1 - 0.015 14.5 0.0 0.51 9.5 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KFX95501.1 - 0.015 15.1 0.0 0.054 13.3 0.0 1.8 1 1 1 2 2 2 0 Hypothetical methyltransferase DUF3419 PF11899.8 KFX95501.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Roc PF08477.13 KFX95501.1 - 0.021 15.0 1.3 6.8 6.9 0.0 2.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_2 PF00891.18 KFX95501.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KFX95501.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CDH-cyt PF16010.5 KFX95502.1 - 8.7e-50 168.9 0.0 1.1e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Eisosome1 PF12757.7 KFX95503.1 - 7.6e-30 103.7 7.0 7.6e-30 103.7 7.0 4.1 3 1 1 4 4 4 1 Eisosome protein 1 SOG2 PF10428.9 KFX95504.1 - 0.23 10.6 3.9 0.28 10.3 3.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IMS_C PF11799.8 KFX95505.1 - 0.049 14.3 0.2 0.62 10.8 0.2 2.1 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain F-box PF00646.33 KFX95506.1 - 9.2e-05 22.2 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain HTH_26 PF13443.6 KFX95506.1 - 0.026 15.0 0.1 0.085 13.3 0.1 1.9 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain FUSC PF04632.12 KFX95506.1 - 0.028 13.0 0.0 0.038 12.5 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APH PF01636.23 KFX95507.1 - 6.5e-12 45.9 0.0 1.2e-11 45.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX95507.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFX95507.1 - 0.015 14.7 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 KFX95507.1 - 0.042 12.7 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 KFX95507.1 - 0.046 13.1 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleocap_ssRNA PF11128.8 KFX95507.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid SPRY PF00622.28 KFX95510.1 - 9.2e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF3645 PF12359.8 KFX95510.1 - 0.022 14.2 18.9 1.8 8.0 1.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3645) Ribosomal_L6 PF00347.23 KFX95511.1 - 1.3e-27 96.2 7.8 3.7e-14 53.1 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ferric_reduct PF01794.19 KFX95527.1 - 1.7e-15 57.2 4.0 2e-15 57.0 1.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FCD PF07729.12 KFX95527.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 FCD domain p450 PF00067.22 KFX95530.1 - 5.3e-14 51.8 0.0 4.4e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFX95532.1 - 9.1e-43 146.5 39.2 9.1e-43 146.5 39.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95532.1 - 2.1e-08 33.5 24.4 8.4e-08 31.5 23.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KFX95532.1 - 0.33 9.3 8.4 0.68 8.2 7.4 2.1 1 1 0 1 1 1 0 Transmembrane secretion effector FlxA PF14282.6 KFX95534.1 - 0.0015 18.5 0.6 0.0042 17.0 0.6 1.8 1 0 0 1 1 1 1 FlxA-like protein Thr_synth_N PF14821.6 KFX95535.1 - 3.2e-28 97.8 0.0 7.7e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KFX95535.1 - 1.6e-19 70.4 0.0 3e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KA1 PF02149.19 KFX95535.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 DUF866 PF05907.13 KFX95538.1 - 1.3e-55 187.5 1.1 1.8e-55 187.1 0.3 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 KFX95538.1 - 2.9e-19 68.5 0.1 4.1e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain PRMT5_TIM PF17285.2 KFX95539.1 - 6.6e-75 251.6 0.0 8.7e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KFX95539.1 - 6.2e-69 231.3 0.0 9.7e-69 230.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFX95539.1 - 6.3e-57 192.3 0.0 9.8e-57 191.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 KFX95540.1 - 1e-23 83.4 0.1 3.8e-23 81.7 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFX95540.1 - 4.4e-19 68.7 0.0 1.2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX95540.1 - 2.3e-11 44.0 0.0 9.4e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX95540.1 - 1.3e-06 28.3 0.7 3.2e-06 27.0 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX95540.1 - 2.7e-06 27.7 0.0 7.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFX95540.1 - 0.00022 20.9 0.1 0.00073 19.2 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFX95540.1 - 0.0055 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KFX95540.1 - 0.014 15.8 0.1 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX95540.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFX95540.1 - 0.091 12.2 0.1 0.49 9.8 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein AAA_23 PF13476.6 KFX95540.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aconitase PF00330.20 KFX95550.1 - 2e-146 488.7 0.0 2.3e-146 488.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Pkinase PF00069.25 KFX95553.1 - 1.1e-11 44.6 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KFX95553.1 - 2.1e-08 34.4 0.1 8.9e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KFX95553.1 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KFX95553.1 - 4.3e-06 26.5 3.3 0.73 10.2 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KFX95553.1 - 4.4e-06 27.0 1.1 0.00095 19.5 0.1 3.5 2 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KFX95553.1 - 0.00023 21.6 0.5 5.4 7.6 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 KFX95553.1 - 0.034 12.7 0.5 1.2 7.6 0.1 2.2 1 1 1 2 2 2 0 Adaptin N terminal region Kinase-like PF14531.6 KFX95553.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CIAPIN1 PF05093.13 KFX95554.1 - 3.3e-41 139.9 2.4 5.4e-41 139.2 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KFX95554.1 - 2.8e-38 131.1 0.0 4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus APH PF01636.23 KFX95555.1 - 1e-13 51.8 0.0 1.6e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KFX95556.1 - 7.2e-09 35.9 0.1 6.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX95556.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_C PF05199.13 KFX95557.1 - 5.8e-30 104.7 0.0 9.6e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFX95557.1 - 1e-25 90.7 0.0 9.2e-25 87.6 0.0 2.3 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFX95557.1 - 6e-05 22.4 0.0 0.0035 16.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX95557.1 - 0.0036 16.6 0.0 0.67 9.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX95557.1 - 0.0044 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX95557.1 - 0.12 11.4 1.1 0.39 9.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KFX95557.1 - 0.14 11.7 0.6 20 4.6 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFX95557.1 - 0.14 12.0 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CFEM PF05730.11 KFX95558.1 - 6.4e-14 51.8 8.8 1.2e-13 50.9 8.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF2759 PF10958.8 KFX95558.1 - 0.072 12.8 4.5 3.7 7.3 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Peroxidase_2 PF01328.17 KFX95559.1 - 3.2e-44 151.7 0.0 4.1e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.25 KFX95560.1 - 9.9e-28 97.2 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95560.1 - 1.2e-19 70.6 0.0 2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HABP4_PAI-RBP1 PF04774.15 KFX95561.1 - 0.093 13.6 3.0 0.22 12.4 3.0 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family adh_short_C2 PF13561.6 KFX95562.1 - 2.8e-43 148.1 0.1 3.5e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX95562.1 - 2.6e-39 134.7 0.1 3.3e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX95562.1 - 7.4e-13 48.8 0.2 1e-12 48.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX95562.1 - 0.058 12.5 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX95562.1 - 0.064 12.7 0.7 0.39 10.1 0.7 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 KFX95563.1 - 8.3e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX95563.1 - 0.00087 19.1 0.3 0.0031 17.3 0.3 2.0 1 0 0 1 1 1 1 F-box domain DUF4780 PF16012.5 KFX95563.1 - 0.044 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) Peptidase_S10 PF00450.22 KFX95564.1 - 1e-112 377.6 0.0 1.2e-112 377.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 KFX95565.1 - 1.5e-81 272.7 0.0 1.7e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 KFX95566.1 - 1.2e-27 95.8 0.1 1.9e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.13 KFX95567.1 - 1.4e-132 442.1 0.0 1.6e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 KFX95568.1 - 2.1e-163 544.2 10.5 2.4e-163 544.0 10.5 1.0 1 0 0 1 1 1 1 ICE2 PB1 PF00564.24 KFX95570.1 - 4.1e-06 26.6 0.0 5.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 PB1 domain PX PF00787.24 KFX95572.1 - 5.9e-15 55.2 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 KFX95572.1 - 8.8e-12 44.4 0.0 1.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX95572.1 - 5.9e-07 29.2 0.0 2.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain TERB2 PF15101.6 KFX95572.1 - 0.0044 17.1 5.2 0.0063 16.6 5.2 1.2 1 0 0 1 1 1 1 Telomere-associated protein TERB2 SH3_2 PF07653.17 KFX95572.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Spt20 PF12090.8 KFX95572.1 - 2.6 7.6 19.1 4.9 6.7 19.1 1.4 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 KFX95572.1 - 3.6 7.6 4.4 4.8 7.2 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 KFX95572.1 - 3.8 6.2 8.2 4.7 5.9 8.2 1.1 1 0 0 1 1 1 0 Presenilin SNF2_N PF00176.23 KFX95588.1 - 5.3e-57 193.1 0.0 6e-56 189.7 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX95588.1 - 8.6e-17 61.5 0.1 5.4e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX95588.1 - 9.2e-08 31.6 0.0 3.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KFX95588.1 - 1.6e-06 28.2 0.0 5.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.29 KFX95588.1 - 0.0048 16.8 21.5 0.013 15.4 9.1 3.3 1 1 1 2 2 2 1 PHD-finger DEAD PF00270.29 KFX95588.1 - 0.0079 16.0 0.0 0.82 9.4 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zf_RING PF16744.5 KFX95588.1 - 0.24 11.5 14.8 8.1 6.6 5.8 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger Clr2_transil PF16761.5 KFX95589.1 - 2.6e-22 79.4 2.5 4.9e-22 78.5 2.5 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KFX95589.1 - 5.4e-10 40.2 0.1 5.7e-09 36.9 0.1 2.4 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 ThiF PF00899.21 KFX95590.1 - 2e-19 69.9 0.0 5.4e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KFX95590.1 - 0.082 13.1 0.2 3.1 8.1 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Fungal_trans PF04082.18 KFX95591.1 - 2.5e-19 69.3 0.0 4.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95591.1 - 4.1e-06 26.8 15.4 7.3e-06 26.0 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.10 KFX95591.1 - 0.71 8.3 7.0 1.1 7.7 7.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-RING_5 PF14634.6 KFX95592.1 - 5.6e-08 32.6 6.3 8.9e-08 32.0 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFX95592.1 - 8.9e-06 25.9 3.3 1.5e-05 25.2 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFX95592.1 - 0.00027 20.7 7.0 0.00048 19.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX95592.1 - 0.00033 20.5 3.9 0.00062 19.6 3.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFX95592.1 - 0.0014 18.5 7.2 0.0025 17.6 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX95592.1 - 0.0045 17.0 3.0 0.011 15.8 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX95592.1 - 0.0051 16.6 5.8 0.0098 15.7 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 KFX95592.1 - 0.0072 16.5 3.8 0.01 15.9 3.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TACC_C PF05010.14 KFX95592.1 - 0.0077 16.0 6.1 0.012 15.4 6.1 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-rbx1 PF12678.7 KFX95592.1 - 0.017 15.4 2.4 0.031 14.6 2.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain CENP-H PF05837.12 KFX95592.1 - 0.025 15.0 7.1 0.042 14.3 7.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Herpes_UL25 PF01499.16 KFX95592.1 - 0.029 12.9 1.2 0.041 12.4 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family zf-C3HC4_4 PF15227.6 KFX95592.1 - 0.039 14.1 5.4 0.077 13.2 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SKA1 PF07160.12 KFX95592.1 - 0.041 13.7 4.6 0.06 13.2 4.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Met_asp_mut_E PF06368.11 KFX95592.1 - 0.067 11.7 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) zf-ANAPC11 PF12861.7 KFX95592.1 - 0.076 13.1 0.7 0.13 12.3 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Drf_FH3 PF06367.16 KFX95592.1 - 0.081 12.5 3.7 0.12 11.9 3.7 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain zf-RING_6 PF14835.6 KFX95592.1 - 0.096 12.6 2.4 0.21 11.5 2.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Exonuc_VII_L PF02601.15 KFX95592.1 - 0.14 11.7 3.9 0.19 11.2 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 KFX95592.1 - 0.2 12.0 11.9 0.29 11.5 11.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-RING_4 PF14570.6 KFX95592.1 - 0.22 11.4 2.7 0.43 10.4 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.6 KFX95592.1 - 0.23 10.8 6.4 0.33 10.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-MIZ PF02891.20 KFX95592.1 - 0.27 11.0 3.9 0.48 10.2 3.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Phage_Mu_Gam PF07352.12 KFX95592.1 - 0.4 10.6 4.9 0.66 9.9 4.9 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Fmp27_WPPW PF10359.9 KFX95592.1 - 0.42 9.4 7.4 0.57 9.0 7.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DNA_ligase_ZBD PF03119.16 KFX95592.1 - 0.43 10.6 4.1 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain RNA_POL_M_15KD PF02150.16 KFX95592.1 - 0.97 9.4 7.9 1.3 9.0 2.0 2.9 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit FapA PF03961.13 KFX95592.1 - 1.3 7.5 5.0 1.8 7.1 5.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 KFX95592.1 - 2.1 7.1 4.9 3 6.6 4.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1272 PF06906.11 KFX95592.1 - 2.9 8.1 7.5 7.5 6.7 7.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) YabA PF06156.13 KFX95592.1 - 6.3 7.5 6.9 11 6.7 6.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA GDA1_CD39 PF01150.17 KFX95593.1 - 1.9e-108 362.8 0.0 2.7e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.12 KFX95594.1 - 1.1e-58 198.1 0.0 1.2e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) CinA_KH PF18146.1 KFX95594.1 - 0.041 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain DUF4743 PF15916.5 KFX95595.1 - 1.4e-09 38.0 0.2 2.6e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KFX95595.1 - 1.6e-07 31.4 0.1 4.3e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain Sirohm_synth_C PF14823.6 KFX95595.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal RNA_pol_Rpb8 PF03870.15 KFX95596.1 - 7.6e-45 152.5 0.0 1e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 KFX95597.1 - 2.8e-92 309.7 0.0 4.2e-92 309.1 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 KFX95598.1 - 4.7e-12 45.8 0.0 1.8e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.21 KFX95599.1 - 1.2e-26 93.7 0.0 5.9e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lipoprotein_18 PF06804.11 KFX95599.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Sec7 PF01369.20 KFX95600.1 - 6.7e-63 211.7 0.0 1e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFX95600.1 - 2.4e-19 69.8 0.0 2.2e-18 66.7 0.0 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Abhydrolase_6 PF12697.7 KFX95601.1 - 3e-09 37.8 1.0 3.6e-09 37.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFX95601.1 - 0.019 14.6 0.2 0.049 13.3 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase Fungal_trans PF04082.18 KFX95602.1 - 3.9e-25 88.4 0.0 4.4e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFX95618.1 - 6.1e-12 45.4 17.4 1.9e-06 28.0 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFX95618.1 - 2.4e-10 40.3 23.6 0.0017 18.7 7.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX95618.1 - 9.6e-07 29.1 20.1 0.041 14.7 5.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX95618.1 - 0.0041 17.1 16.4 0.35 10.9 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KFX95618.1 - 0.0081 16.0 3.2 4.3 7.2 0.2 3.4 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 KFX95618.1 - 0.0091 15.8 3.1 0.19 11.6 0.7 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.12 KFX95618.1 - 0.022 15.1 11.3 0.051 13.9 7.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rpr2 PF04032.16 KFX95618.1 - 0.12 12.7 3.0 0.6 10.4 0.8 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 KFX95618.1 - 0.14 12.3 5.6 0.31 11.2 1.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFX95618.1 - 0.17 12.2 9.6 0.65 10.4 3.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.9 KFX95618.1 - 0.31 11.1 6.4 0.31 11.1 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger domain DZR PF12773.7 KFX95618.1 - 0.91 9.6 6.4 5.6 7.1 6.4 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.6 KFX95618.1 - 1.2 9.1 6.6 0.13 12.2 0.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 KFX95618.1 - 1.6 9.1 6.9 8 6.8 0.1 3.1 2 1 1 3 3 3 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KFX95618.1 - 3.8 7.5 5.2 17 5.5 5.2 2.0 1 1 0 1 1 1 0 zinc-ribbons GAGA PF09237.11 KFX95618.1 - 6.1 6.7 8.4 6.1 6.7 0.9 3.2 1 1 2 3 3 3 0 GAGA factor zf-met PF12874.7 KFX95618.1 - 7.5 7.1 12.3 13 6.3 1.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type EF-hand_1 PF00036.32 KFX95620.1 - 9.2e-19 65.5 7.4 1.4e-08 33.7 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFX95620.1 - 2.3e-18 66.4 3.0 3e-11 43.6 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFX95620.1 - 3.7e-16 57.6 4.9 2.8e-07 29.9 0.3 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFX95620.1 - 2.4e-15 56.1 7.7 6.7e-08 32.3 0.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFX95620.1 - 5.2e-08 32.0 6.3 0.00017 20.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 KFX95620.1 - 0.00012 21.9 0.2 0.00098 19.0 0.0 2.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFX95620.1 - 0.00081 19.7 0.0 0.072 13.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Methyltransf_3 PF01596.17 KFX95620.1 - 0.029 13.5 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Caleosin PF05042.13 KFX95620.1 - 0.039 13.9 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein DUF150 PF02576.17 KFX95620.1 - 0.12 12.8 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 RimP N-terminal domain Metal_resist PF13801.6 KFX95620.1 - 0.13 12.4 7.1 0.1 12.8 4.7 2.0 2 0 0 2 2 2 0 Heavy-metal resistance GDI PF00996.18 KFX95625.1 - 3.1e-25 88.6 0.0 1.7e-24 86.1 0.0 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor Ferric_reduct PF01794.19 KFX95626.1 - 8.7e-18 64.6 6.1 8.7e-18 64.6 6.1 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX95626.1 - 1.1e-15 58.1 0.0 8e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX95626.1 - 3.3e-11 43.2 0.0 8.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFX95626.1 - 0.0054 17.4 0.0 6.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain AIM3 PF17096.5 KFX95626.1 - 0.034 15.1 0.2 0.034 15.1 0.2 4.2 2 1 1 3 3 3 0 Altered inheritance of mitochondria protein 3 DUF4405 PF14358.6 KFX95626.1 - 1.2 9.8 6.9 0.16 12.5 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PDR_CDR PF06422.12 KFX95627.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 CDR ABC transporter DUF4562 PF15123.6 KFX95627.1 - 0.0051 16.8 0.1 0.0062 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) VirB8 PF04335.13 KFX95627.1 - 0.0099 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 VirB8 protein DUF2417 PF10329.9 KFX95627.1 - 0.11 12.0 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Sec63 PF02889.16 KFX95629.1 - 5.3e-30 104.4 0.0 8.2e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFX95629.1 - 8e-23 81.1 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX95629.1 - 3e-10 40.4 0.0 8.6e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX95629.1 - 2.8e-07 30.8 0.0 1.7e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFX95629.1 - 0.00049 19.9 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 KFX95629.1 - 0.00052 20.6 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 KFX95629.1 - 0.00068 20.0 0.1 0.0069 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Cdd1 PF11731.8 KFX95629.1 - 0.0016 18.6 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus UvrD-helicase PF00580.21 KFX95629.1 - 0.013 15.0 0.1 0.059 12.9 0.0 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFX95629.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nuc_sug_transp PF04142.15 KFX95630.1 - 6.7e-104 347.4 13.4 9.3e-104 347.0 13.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFX95630.1 - 2e-06 28.0 27.1 0.00019 21.6 4.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFX95630.1 - 6.1e-06 25.7 14.8 3.5e-05 23.1 14.8 2.2 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 KFX95630.1 - 0.0068 16.0 0.1 0.0068 16.0 0.1 2.2 2 1 0 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 KFX95630.1 - 0.013 14.8 13.5 0.04 13.3 8.0 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 KFX95630.1 - 0.39 10.9 7.9 3.7 7.8 0.4 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) TMEM234 PF10639.9 KFX95630.1 - 1.7 8.7 7.5 0.56 10.3 0.3 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 HPP PF04982.13 KFX95630.1 - 8.5 6.6 11.3 0.43 10.8 0.1 3.3 3 1 0 3 3 3 0 HPP family Cyclin_N PF00134.23 KFX95631.1 - 2.3e-14 53.2 0.2 5.5e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFX95631.1 - 1.6e-06 28.6 0.5 1.2e-05 25.7 0.1 2.4 2 1 0 2 2 2 1 Cyclin DUF3920 PF13058.6 KFX95631.1 - 0.27 11.5 2.0 0.24 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) WD40 PF00400.32 KFX95632.1 - 2.9e-47 157.7 20.3 3.2e-08 34.1 0.7 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX95632.1 - 5.8e-10 39.3 0.3 0.00092 19.5 0.0 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX95632.1 - 4.5e-08 32.2 0.0 0.003 16.3 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFX95632.1 - 0.0024 16.7 0.1 1.9 7.1 0.0 2.6 2 1 0 2 2 2 2 Nup133 N terminal like HECW_N PF16562.5 KFX95632.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Pox_A_type_inc PF04508.12 KFX95632.1 - 0.16 11.8 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Na_Ca_ex PF01699.24 KFX95633.1 - 3.5e-45 153.7 41.1 8.8e-25 87.4 17.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFA2_Winged_2 PF18121.1 KFX95634.1 - 6.5e-25 86.6 0.1 6.9e-24 83.3 0.1 2.3 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KFX95634.1 - 3.6e-19 68.8 0.1 1.6e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain LEA_3 PF03242.13 KFX95634.1 - 0.076 13.7 3.5 0.81 10.5 1.2 2.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF1771 PF08590.10 KFX95634.1 - 0.081 13.3 0.5 0.18 12.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) TPR_MLP1_2 PF07926.12 KFX95635.1 - 1.6e-37 128.4 23.7 1.6e-37 128.4 23.7 19.7 7 5 8 16 16 16 3 TPR/MLP1/MLP2-like protein LPP PF04728.13 KFX95635.1 - 0.0035 17.7 4.7 0.0035 17.7 4.7 18.3 19 4 2 22 22 22 1 Lipoprotein leucine-zipper HALZ PF02183.18 KFX95635.1 - 0.021 15.0 0.5 0.021 15.0 0.5 14.7 14 1 1 15 15 15 0 Homeobox associated leucine zipper Hexapep PF00132.24 KFX95636.1 - 9.6e-11 41.0 7.7 7.8e-07 28.6 0.6 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX95636.1 - 8.9e-05 22.2 12.0 0.44 10.3 0.6 4.1 2 2 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFX95636.1 - 0.13 10.4 0.1 0.17 9.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Complex1_51K PF01512.17 KFX95637.1 - 2.4e-46 157.4 0.0 4.1e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KFX95637.1 - 2.5e-29 101.2 1.4 3.1e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KFX95637.1 - 4.3e-09 36.1 0.0 9.4e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Complex1_LYR_2 PF13233.6 KFX95638.1 - 3.9e-22 78.8 0.8 5.3e-22 78.4 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Phe_ZIP PF08916.11 KFX95638.1 - 0.059 14.1 0.6 0.46 11.2 0.2 2.2 2 0 0 2 2 2 0 Phenylalanine zipper MMR_HSR1 PF01926.23 KFX95639.1 - 8.8e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX95639.1 - 1.4e-06 28.0 0.0 1.4e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX95639.1 - 4.9e-05 23.3 0.2 0.0068 16.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFX95639.1 - 0.00051 20.1 0.1 0.049 13.7 0.5 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KFX95639.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFX95639.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 KFX95639.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KFX95639.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KFX95639.1 - 0.18 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFX95639.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin PI_PP_I PF18363.1 KFX95640.1 - 0.016 15.3 0.0 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain MOZ_SAS PF01853.18 KFX95643.1 - 1.9e-74 249.2 0.0 3.1e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFX95643.1 - 9.5e-20 70.0 3.8 2e-19 68.9 3.8 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KFX95643.1 - 6.3e-12 45.4 8.1 2.6e-11 43.4 8.1 2.1 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KFX95643.1 - 0.00076 19.3 8.2 0.00076 19.3 8.2 1.9 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.20 KFX95643.1 - 0.12 12.1 1.0 0.27 11.0 1.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Acetyltransf_7 PF13508.7 KFX95643.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GRP PF07172.11 KFX95643.1 - 0.16 12.6 1.8 0.56 10.9 1.8 2.0 1 0 0 1 1 1 0 Glycine rich protein family C1_1 PF00130.22 KFX95643.1 - 4.4 7.3 5.5 0.49 10.3 0.7 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MWFE PF15879.5 KFX95644.1 - 7.5e-23 80.5 0.0 1.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Pro_CA PF00484.19 KFX95645.1 - 3.9e-47 160.4 0.1 4.7e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 KFX95646.1 - 1.3e-21 76.1 0.7 2.3e-21 75.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zn-ribbon_14 PF16503.5 KFX95647.1 - 7.1e-19 67.0 3.1 7.1e-19 67.0 3.1 3.5 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 KFX95647.1 - 2.1e-18 66.7 0.0 3.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 KFX95647.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 KFX95647.1 - 0.025 14.1 0.8 0.025 14.1 0.8 4.1 5 0 0 5 5 5 0 RecR protein DUF4428 PF14471.6 KFX95647.1 - 0.94 9.5 4.9 0.29 11.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4_3 PF13920.6 KFX95647.1 - 7.4 6.5 12.3 0.18 11.7 1.9 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) OCD_Mu_crystall PF02423.15 KFX95648.1 - 2.4e-08 33.3 0.4 6.8e-05 22.0 0.1 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFX95648.1 - 0.0058 16.7 0.0 1.6 8.8 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 KFX95649.1 - 1.6e-65 221.2 0.0 2.7e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KFX95649.1 - 1.1e-60 205.5 0.0 1.5e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX95649.1 - 1.3e-30 106.8 0.0 2.7e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KFX95649.1 - 3.5e-05 23.2 0.2 0.00024 20.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFX95649.1 - 0.0002 21.5 0.0 0.00066 19.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX95649.1 - 0.00025 20.2 0.0 0.13 11.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX95649.1 - 0.0028 17.3 0.2 0.019 14.6 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX95649.1 - 0.0041 16.2 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX95649.1 - 0.0043 16.3 0.1 0.92 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX95649.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.18 KFX95650.1 - 0.00016 21.7 10.8 0.00016 21.7 10.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KFX95651.1 - 2.1e-23 82.7 0.6 3.6e-23 82.0 0.4 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX95651.1 - 8.7e-17 62.4 0.0 1.6e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX95651.1 - 1.2e-09 38.1 0.0 3.1e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HasA PF06438.12 KFX95651.1 - 0.067 12.8 0.1 0.38 10.4 0.0 1.9 1 1 1 2 2 2 0 Heme-binding protein A (HasA) DAO PF01266.24 KFX95652.1 - 1.3e-29 103.9 0.4 1.5e-29 103.7 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 KFX95652.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus PTR2 PF00854.21 KFX95653.1 - 1.3e-44 152.7 4.1 2.2e-44 151.9 4.1 1.3 1 0 0 1 1 1 1 POT family NLPC_P60 PF00877.19 KFX95654.1 - 9.1e-22 77.1 0.1 2e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 NlpC/P60 family SH3_16 PF18348.1 KFX95654.1 - 1.6e-05 24.6 0.4 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial dipeptidyl-peptidase Sh3 domain Abhydrolase_1 PF00561.20 KFX95655.1 - 9.4e-29 100.8 0.0 1.6e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX95655.1 - 2.9e-10 39.8 0.0 1e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX95655.1 - 3.4e-07 31.1 0.0 6.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFX95655.1 - 0.0037 17.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Zn_clus PF00172.18 KFX95655.1 - 0.0056 16.8 2.6 0.0091 16.1 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase PF00756.20 KFX95655.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Helo_like_N PF17111.5 KFX95657.1 - 6.9e-11 41.9 0.6 1.1e-10 41.2 0.6 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Alph_Pro_TM PF09608.10 KFX95658.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) DUF966 PF06136.13 KFX95658.1 - 1.9 8.1 11.3 3 7.5 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Fumble PF03630.14 KFX95659.1 - 1e-146 488.4 0.0 1.3e-146 488.0 0.0 1.2 1 0 0 1 1 1 1 Fumble RhaA PF06134.11 KFX95659.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Ctr PF04145.15 KFX95669.1 - 2.8e-07 31.2 0.0 4.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Diphthamide_syn PF01866.17 KFX95671.1 - 2.8e-50 171.5 0.0 3.3e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SesA PF17107.5 KFX95672.1 - 0.00029 21.0 0.3 0.00056 20.1 0.2 1.5 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KFX95672.1 - 0.00037 20.6 23.7 0.00092 19.3 2.0 3.1 2 1 0 2 2 2 1 Sigma domain on NACHT-NTPases Pox_Ag35 PF03286.14 KFX95672.1 - 0.12 12.1 0.5 0.21 11.4 0.2 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CdiI_2 PF18593.1 KFX95672.1 - 0.16 12.7 0.1 0.71 10.6 0.1 1.9 1 1 1 2 2 2 0 CdiI immunity protein PHM7_ext PF12621.8 KFX95673.1 - 3.7e-14 52.7 0.0 4.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Thyroglob_assoc PF16597.5 KFX95673.1 - 0.13 12.6 0.2 0.22 11.9 0.2 1.4 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain DcuA_DcuB PF03605.14 KFX95677.1 - 0.072 12.0 0.2 0.085 11.7 0.2 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF2951 PF11166.8 KFX95677.1 - 0.12 12.6 2.3 0.15 12.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Jak1_Phl PF17887.1 KFX95677.1 - 0.19 11.7 3.7 0.22 11.5 3.7 1.1 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain FUSC PF04632.12 KFX95682.1 - 0.024 13.2 2.5 0.034 12.7 2.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DSPc PF00782.20 KFX95688.1 - 5e-09 36.1 0.0 8.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX95688.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFX95688.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family APH PF01636.23 KFX95689.1 - 5.3e-07 29.8 0.0 2.1e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX95689.1 - 7.2e-06 25.7 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase BTB PF00651.31 KFX95690.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain HUN PF08729.10 KFX95690.1 - 0.14 12.2 1.4 0.27 11.2 1.4 1.5 1 0 0 1 1 1 0 HPC2 and ubinuclein domain MFS_1 PF07690.16 KFX95691.1 - 4.3e-30 104.8 14.0 4.3e-30 104.8 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95691.1 - 7.3e-08 31.7 7.7 7.3e-08 31.7 7.7 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KFX95691.1 - 9.9e-05 21.4 0.5 0.00018 20.5 0.5 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Actin PF00022.19 KFX95701.1 - 6.4e-37 127.1 0.0 7.9e-34 116.9 0.0 2.4 1 1 0 2 2 2 2 Actin GvpK PF05121.12 KFX95701.1 - 2.2 8.3 8.7 0.5 10.4 0.2 3.2 2 1 1 3 3 3 0 Gas vesicle protein K DASH_Dad4 PF08650.10 KFX95702.1 - 7.7e-33 112.3 5.9 8.4e-33 112.2 5.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KFX95702.1 - 0.01 16.0 0.3 0.012 15.8 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor LTD PF00932.19 KFX95702.1 - 0.098 13.0 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 Lamin Tail Domain YL1_C PF08265.11 KFX95703.1 - 2.1e-15 56.2 0.2 3.2e-15 55.6 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 KFX95704.1 - 1e-14 54.9 13.5 1.3e-14 54.6 13.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 KFX95704.1 - 1.5 8.2 4.7 0.32 10.4 1.0 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Pyridoxal_deC PF00282.19 KFX95705.1 - 1.8e-109 365.9 0.0 2.2e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NTP_transf_9 PF04248.12 KFX95706.1 - 1.5e-32 111.3 2.0 1.7e-32 111.2 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Zn_clus PF00172.18 KFX95707.1 - 6.2e-09 35.8 7.3 6.2e-09 35.8 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_CA PF00484.19 KFX95708.1 - 1.9e-28 99.7 0.0 2.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AhpC-TSA PF00578.21 KFX95713.1 - 1.2e-28 99.5 0.0 2.5e-28 98.5 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KFX95713.1 - 1.7e-19 70.0 0.0 2.3e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFX95713.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 KFX95713.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Acetyltransf_3 PF13302.7 KFX95714.1 - 1.4e-20 74.3 0.0 2.1e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX95714.1 - 7.9e-07 29.3 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FAT PF02259.23 KFX95715.1 - 3.6e-72 243.5 6.4 7.9e-72 242.3 6.4 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KFX95715.1 - 2.8e-31 109.2 0.1 6.1e-31 108.1 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFX95715.1 - 1.7e-05 24.6 0.1 4.3e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 FATC domain U3snoRNP10 PF12397.8 KFX95715.1 - 3.3 8.1 7.3 11 6.4 0.4 4.5 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Fungal_trans PF04082.18 KFX95716.1 - 2.5e-24 85.7 0.0 1.4e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.6 KFX95716.1 - 7.8e-08 33.1 0.0 2.1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KFX95716.1 - 1.5e-06 28.2 13.6 2.7e-06 27.4 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3958 PF13125.6 KFX95716.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Gal4_dimer PF03902.13 KFX95716.1 - 0.14 12.3 0.2 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain Metallophos PF00149.28 KFX95717.1 - 1.5e-14 55.0 0.5 2.3e-14 54.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCMT PF01135.19 KFX95718.1 - 5.8e-48 163.4 0.0 5.8e-47 160.1 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KFX95718.1 - 2e-19 70.0 0.0 3.4e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_31 PF13847.6 KFX95718.1 - 8.4e-08 32.1 0.1 2.4e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Pkinase_Tyr PF07714.17 KFX95718.1 - 5.6e-07 29.1 0.0 5.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_25 PF13649.6 KFX95718.1 - 0.00013 22.6 0.1 0.00032 21.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFX95718.1 - 0.00014 21.9 0.0 0.00038 20.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95718.1 - 0.0049 17.5 0.1 0.012 16.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX95718.1 - 0.0096 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX95718.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KFX95718.1 - 0.045 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 KFX95718.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MFS_1 PF07690.16 KFX95719.1 - 7.2e-36 123.8 33.7 1.8e-34 119.2 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFX95720.1 - 9.4e-49 166.2 15.5 9.4e-49 166.2 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95720.1 - 7.5e-11 41.5 24.0 7.7e-11 41.5 7.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KFX95720.1 - 3.9e-05 22.2 2.6 3.9e-05 22.2 2.6 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 KFX95720.1 - 0.0015 17.5 3.5 0.002 17.1 0.7 2.3 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX95720.1 - 0.49 9.2 10.1 0.2 10.5 1.2 3.1 2 1 2 4 4 4 0 MFS_1 like family Isochorismatase PF00857.20 KFX95721.1 - 6.7e-32 111.1 0.0 7.5e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.18 KFX95722.1 - 2e-07 30.3 0.3 2e-07 30.3 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain WD40 PF00400.32 KFX95727.1 - 2.9e-06 27.9 2.6 2 9.4 0.5 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat T2SSF PF00482.23 KFX95727.1 - 5.7 6.9 6.0 0.44 10.5 0.3 2.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F STT3 PF02516.14 KFX95728.1 - 5.1e-147 490.7 35.5 5.7e-142 474.1 34.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KFX95728.1 - 1.2e-18 67.2 0.2 3.8e-18 65.6 0.2 1.9 1 0 0 1 1 1 1 ATP synthase E chain SIL1 PF16782.5 KFX95729.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Chromo PF00385.24 KFX95729.1 - 0.028 14.3 1.6 0.062 13.2 1.6 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain SET PF00856.28 KFX95731.1 - 6.5e-11 42.9 0.3 1.1e-10 42.2 0.3 1.4 1 0 0 1 1 1 1 SET domain SPT2 PF08243.11 KFX95732.1 - 3.2e-08 34.1 15.3 3.2e-08 34.1 15.3 2.1 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 KFX95733.1 - 5.9e-26 90.9 9.3 6.8e-26 90.7 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 KFX95734.1 - 3e-32 110.4 0.4 4.2e-32 109.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 MFAP1 PF06991.11 KFX95757.1 - 2.9e-71 239.8 28.8 2.9e-71 239.8 28.8 2.4 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing CRS1_YhbY PF01985.21 KFX95757.1 - 0.16 12.1 3.6 6.4 7.0 1.5 2.5 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain Egh16-like PF11327.8 KFX95768.1 - 9.6e-16 58.7 0.2 1.1e-15 58.6 0.2 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor AMP-binding PF00501.28 KFX95769.1 - 5.7e-94 315.1 0.0 7.3e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX95769.1 - 7e-12 46.2 0.1 1.5e-11 45.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 KFX95770.1 - 4e-14 52.5 0.0 1.8e-09 37.2 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX95770.1 - 7.2e-12 45.2 0.0 2.3e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX95770.1 - 9.2e-10 37.6 0.0 4.5e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX95770.1 - 5.5e-08 32.4 0.0 1.9e-05 24.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SnoaL_4 PF13577.6 KFX95770.1 - 0.00054 20.1 0.1 0.0037 17.4 0.1 2.2 2 0 0 2 2 2 1 SnoaL-like domain Shikimate_DH PF01488.20 KFX95770.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX95770.1 - 0.00087 19.8 0.2 0.01 16.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 KFX95770.1 - 0.00099 19.7 0.1 0.0065 17.1 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 KFX95770.1 - 0.0092 16.4 0.1 0.028 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KFX95770.1 - 0.054 13.8 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.16 KFX95771.1 - 6.1e-31 107.6 37.5 6.1e-31 107.6 37.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFX95771.1 - 0.012 15.4 3.9 0.023 14.4 3.9 1.6 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 LRR_6 PF13516.6 KFX95772.1 - 0.0023 17.9 15.0 9.9 6.5 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LDcluster4 PF18306.1 KFX95775.1 - 0.0016 18.0 0.1 0.0016 18.0 0.1 1.0 1 0 0 1 1 1 1 SLOG cluster4 family tRNA-synt_1 PF00133.22 KFX95776.1 - 6.1e-161 536.7 0.0 1.2e-160 535.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Kinesin PF00225.23 KFX95776.1 - 2.7e-107 358.5 0.3 2.7e-107 358.5 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFX95776.1 - 2.3e-22 79.5 0.0 9.4e-22 77.6 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding tRNA-synt_1g PF09334.11 KFX95776.1 - 8e-19 67.6 2.5 8.8e-10 37.9 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFX95776.1 - 1e-16 61.3 0.0 3.3e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Microtub_bind PF13931.6 KFX95776.1 - 1.4e-11 44.9 0.8 1.4e-11 44.9 0.8 4.6 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Fungal_trans_2 PF11951.8 KFX95776.1 - 0.00094 18.1 0.2 0.00094 18.1 0.2 3.7 4 0 0 4 4 4 2 Fungal specific transcription factor domain tRNA-synt_1_2 PF13603.6 KFX95776.1 - 0.022 14.2 0.2 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 KFX95776.1 - 0.18 11.7 0.5 0.45 10.4 0.5 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SMK-1 PF04802.15 KFX95786.1 - 2.2e-77 259.3 0.2 4.4e-77 258.2 0.2 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ank_2 PF12796.7 KFX95786.1 - 2e-58 195.0 0.0 2.1e-12 47.5 0.0 6.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95786.1 - 2.7e-42 142.6 0.0 1.3e-07 32.1 0.0 7.0 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX95786.1 - 7.4e-38 124.3 0.0 0.02 15.4 0.0 11.5 10 0 0 10 10 10 9 Ankyrin repeat Ank PF00023.30 KFX95786.1 - 3.1e-34 115.9 0.0 0.0013 19.1 0.0 11.4 11 1 1 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KFX95786.1 - 4.4e-34 116.1 0.1 1.5e-05 25.2 0.0 8.3 2 2 7 9 9 9 8 Ankyrin repeats (many copies) AAA_22 PF13401.6 KFX95786.1 - 3.1e-05 24.3 0.0 9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX95786.1 - 0.00061 19.7 0.6 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 KFX95786.1 - 0.0011 18.3 1.7 0.005 16.2 1.7 2.0 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KFX95786.1 - 0.1 12.8 0.5 19 5.5 0.0 2.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MOR2-PAG1_N PF14222.6 KFX95790.1 - 1.2e-224 747.4 0.1 3e-224 746.1 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFX95790.1 - 5.4e-91 305.0 0.4 1.6e-90 303.4 0.1 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFX95790.1 - 8.4e-35 119.8 7.7 1.5e-12 46.1 0.1 3.8 2 1 2 4 4 4 3 Cell morphogenesis central region HEAT_2 PF13646.6 KFX95790.1 - 0.0015 18.9 1.1 0.19 12.1 0.0 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KFX95790.1 - 0.026 14.8 0.1 5.7 7.5 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Cortex-I_coil PF09304.10 KFX95790.1 - 0.051 13.8 0.4 0.26 11.5 0.4 2.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil HEAT_EZ PF13513.6 KFX95790.1 - 0.96 10.0 3.6 31 5.2 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat AMMECR1 PF01871.17 KFX95792.1 - 2.2e-45 154.3 0.0 3.2e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Esterase_phd PF10503.9 KFX95792.1 - 3e-06 26.9 0.0 0.00049 19.6 0.0 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.20 KFX95792.1 - 9.2e-05 22.2 0.1 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 KFX95792.1 - 0.002 17.6 0.3 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF5342 PF17277.2 KFX95792.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5342) AXE1 PF05448.12 KFX95792.1 - 0.12 11.0 0.0 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) 4HBT_3 PF13622.6 KFX95793.1 - 1.1e-28 101.1 0.2 1.4e-28 100.9 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos PF00149.28 KFX95794.1 - 5e-37 128.4 0.9 1.7e-36 126.6 0.6 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Golgin_A5 PF09787.9 KFX95794.1 - 0.0028 17.2 2.1 0.0028 17.2 2.1 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 Mt_ATP-synt_D PF05873.12 KFX95794.1 - 0.016 15.1 0.5 0.016 15.1 0.5 1.8 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Chlorosome_CsmC PF11098.8 KFX95794.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C XLF PF09302.11 KFX95794.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Hid1 PF12722.7 KFX95794.1 - 1.6 6.7 7.3 2.3 6.2 7.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 KFX95794.1 - 8.8 3.3 17.1 13 2.8 17.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Exo84_C PF16528.5 KFX95795.1 - 7.9e-75 251.2 1.1 7.9e-75 251.2 1.1 2.1 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KFX95795.1 - 8.9e-16 57.7 2.8 8.9e-16 57.7 2.8 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KFX95795.1 - 0.023 14.8 0.3 0.023 14.8 0.3 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4618 PF15397.6 KFX95795.1 - 0.098 12.1 3.1 0.17 11.3 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2383 PF09537.10 KFX95795.1 - 0.45 10.9 3.8 5.6 7.4 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF2130 PF09903.9 KFX95795.1 - 0.88 8.8 7.9 3.8 6.7 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) APG6_N PF17675.1 KFX95795.1 - 0.91 10.1 7.5 0.084 13.4 0.6 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFX95795.1 - 3.9 6.7 7.0 0.72 9.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2443 PF10398.9 KFX95795.1 - 4.3 7.5 5.0 12 6.0 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) MAS20 PF02064.15 KFX95796.1 - 1.2e-47 161.2 1.0 1.4e-47 161.0 1.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 KFX95796.1 - 0.0055 17.0 1.0 0.13 12.6 1.0 2.5 1 1 0 1 1 1 1 Nif11 domain TetR_C_36 PF18598.1 KFX95796.1 - 0.067 13.2 0.2 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4703 PF15775.5 KFX95796.1 - 0.39 10.5 2.8 0.59 9.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) DHC_N1 PF08385.12 KFX95797.1 - 2.4e-127 426.0 7.3 2.4e-127 426.0 7.3 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFX95797.1 - 2.3e-126 421.2 0.0 9.5e-126 419.2 0.0 2.2 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFX95797.1 - 5.9e-114 381.3 6.7 5.9e-114 381.3 6.7 5.6 4 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFX95797.1 - 1e-73 247.1 1.2 1e-73 247.1 1.2 4.5 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFX95797.1 - 4.6e-67 226.1 0.0 3.8e-66 223.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KFX95797.1 - 2.1e-42 144.7 0.1 2e-35 122.0 0.0 5.2 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KFX95797.1 - 3.3e-36 125.0 6.3 3.3e-36 125.0 6.3 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KFX95797.1 - 6.6e-32 110.4 0.9 1.6e-11 44.4 0.0 7.1 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFX95797.1 - 2e-29 102.1 3.6 1e-27 96.6 0.0 4.7 5 0 0 5 5 4 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFX95797.1 - 6.2e-28 97.7 0.0 1.7e-27 96.2 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFX95797.1 - 1.9e-15 57.3 0.1 0.0095 16.2 0.0 6.3 5 0 0 5 5 4 3 AAA domain Dynein_AAA_lid PF17852.1 KFX95797.1 - 2.6e-15 56.6 0.9 7.4e-15 55.2 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFX95797.1 - 5.9e-14 52.6 0.0 0.0044 17.5 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX95797.1 - 4.3e-10 40.2 0.0 1.8 8.9 0.0 7.1 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 KFX95797.1 - 9.6e-10 39.1 0.9 0.018 15.6 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 KFX95797.1 - 1.3e-08 35.1 9.2 0.024 14.8 0.0 5.6 6 0 0 6 6 4 3 AAA domain T2SSE PF00437.20 KFX95797.1 - 1.2e-07 31.1 0.0 0.019 14.0 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.6 KFX95797.1 - 6.1e-05 23.4 1.5 0.28 11.5 0.0 4.8 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFX95797.1 - 0.00012 21.6 4.4 0.68 9.3 0.0 4.8 5 0 0 5 5 4 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KFX95797.1 - 0.00026 20.4 0.0 2.4 7.5 0.0 3.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 KFX95797.1 - 0.00027 21.1 0.2 0.0022 18.2 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 KFX95797.1 - 0.00032 20.4 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX95797.1 - 0.001 18.9 3.8 34 4.1 0.0 5.1 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.6 KFX95797.1 - 0.0013 18.5 0.1 11 5.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFX95797.1 - 0.0013 19.2 4.9 4.3 7.8 0.0 5.1 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 KFX95797.1 - 0.0018 17.9 1.0 0.26 10.8 0.0 3.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KFX95797.1 - 0.0036 17.1 1.1 0.71 9.6 0.0 4.4 5 0 0 5 5 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX95797.1 - 0.0089 16.4 0.1 53 4.3 0.0 4.8 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KFX95797.1 - 0.013 15.4 0.3 6.9 6.6 0.0 4.3 5 0 0 5 5 4 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KFX95797.1 - 0.039 13.2 0.1 17 4.6 0.1 3.8 3 0 0 3 3 3 0 Zeta toxin Pox_A32 PF04665.12 KFX95797.1 - 0.047 13.1 0.6 24 4.3 0.0 3.8 4 0 0 4 4 3 0 Poxvirus A32 protein PduV-EutP PF10662.9 KFX95797.1 - 0.053 13.3 0.4 11 5.7 0.1 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFX95797.1 - 0.064 13.1 0.2 9.4 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 KFX95797.1 - 0.087 12.7 0.1 9.1 6.2 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFX95797.1 - 0.13 12.2 0.1 46 3.9 0.0 3.7 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 KFX95797.1 - 0.16 11.9 9.8 32 4.4 0.0 5.7 5 0 0 5 5 4 0 NACHT domain TsaE PF02367.17 KFX95797.1 - 0.2 11.6 4.5 22 5.1 0.0 4.2 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4482 PF14818.6 KFX95797.1 - 0.36 11.7 9.4 30 5.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) ING PF12998.7 KFX95797.1 - 0.46 11.1 6.2 6.5 7.4 0.0 4.5 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding SRP54 PF00448.22 KFX95797.1 - 0.51 9.9 3.2 56 3.3 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF3867 PF12983.7 KFX95797.1 - 0.79 9.7 10.8 1.4 8.9 0.1 3.4 4 0 0 4 4 2 0 Protein of unknown function (DUF3867) Phage_GP20 PF06810.11 KFX95797.1 - 0.85 9.4 19.3 1.7 8.5 7.3 4.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 ERM PF00769.19 KFX95797.1 - 1.5 8.5 25.5 0.9 9.3 1.7 3.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family BRE1 PF08647.11 KFX95797.1 - 5 7.3 21.7 0.16 12.0 3.2 4.9 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase MbeB_N PF04837.12 KFX95797.1 - 5.7 7.3 9.8 2.6 8.4 0.1 4.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Sulfotransfer_4 PF17784.1 KFX95798.1 - 7.6e-30 104.3 0.1 1.1e-29 103.9 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Fungal_trans PF04082.18 KFX95800.1 - 9.6e-26 90.4 3.2 1.8e-25 89.5 3.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95800.1 - 8.1e-10 38.7 9.2 1.6e-09 37.7 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F15 PF04596.12 KFX95800.1 - 0.045 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 Amidohydro_2 PF04909.14 KFX95801.1 - 1.6e-21 77.3 0.0 2e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.24 KFX95802.1 - 3.9e-76 256.7 21.9 3.9e-76 256.7 21.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter NmrA PF05368.13 KFX95802.1 - 1.3e-27 96.9 0.0 2.8e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family ArAE_2_N PF10337.9 KFX95802.1 - 1.4e-22 80.4 22.9 5.5e-22 78.5 10.1 3.5 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal NAD_binding_10 PF13460.6 KFX95802.1 - 2.1e-12 47.3 0.0 3.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding FUSC_2 PF13515.6 KFX95802.1 - 1.2e-11 44.8 21.9 1.2e-11 44.8 21.9 5.5 5 2 0 5 5 5 1 Fusaric acid resistance protein-like MFS_1 PF07690.16 KFX95802.1 - 2.2e-11 43.3 49.8 2.3e-10 39.9 23.0 4.4 2 2 1 3 3 3 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX95802.1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX95802.1 - 0.0039 17.1 0.2 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 KR domain ArAE_2 PF10334.9 KFX95802.1 - 0.013 15.4 0.0 2.6 7.8 0.0 3.0 3 0 0 3 3 3 0 Aromatic acid exporter family member 2 Sacchrp_dh_NADP PF03435.18 KFX95802.1 - 0.034 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glu-tRNAGln PF02686.15 KFX95835.1 - 4.4e-11 42.9 1.6 1.1e-10 41.7 1.6 1.6 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 KFX95836.1 - 2.5e-112 374.9 13.5 2.8e-112 374.7 13.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFX95836.1 - 3e-07 30.6 6.6 0.13 12.6 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX95836.1 - 1.2e-06 28.1 4.6 0.034 14.2 0.3 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95836.1 - 0.00051 20.1 11.6 0.047 13.9 0.4 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX95836.1 - 0.0036 17.1 8.2 3.3 7.7 0.1 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX95836.1 - 0.006 16.6 9.6 3.1 8.2 0.1 5.4 2 1 4 6 6 6 2 Tetratricopeptide repeat DUF2521 PF10730.9 KFX95836.1 - 0.018 15.0 0.7 0.048 13.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2521) TPR_6 PF13174.6 KFX95836.1 - 0.51 11.1 11.6 13 6.7 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat BING4CT PF08149.11 KFX95837.1 - 7.2e-40 134.7 0.0 1.9e-35 120.5 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KFX95837.1 - 1.4e-06 28.5 0.1 2.4 8.5 0.0 5.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX95837.1 - 4.7e-05 24.1 0.0 0.11 13.5 0.0 4.0 3 1 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KFX95837.1 - 0.032 13.3 0.1 0.077 12.0 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region RIBIOP_C PF04950.12 KFX95838.1 - 1e-111 373.1 0.0 1.5e-111 372.5 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFX95838.1 - 1.8e-16 60.0 0.0 5.8e-16 58.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain FA_desaturase PF00487.24 KFX95839.1 - 1.3e-26 94.0 12.3 1.9e-26 93.5 12.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFX95839.1 - 2e-17 62.4 0.7 3.8e-17 61.5 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KFX95840.1 - 3.8e-25 87.9 0.2 7.2e-25 87.0 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KFX95840.1 - 0.0096 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 KFX95841.1 - 1.2e-06 28.6 0.0 3.9e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 KFX95841.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.7 KFX95841.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFX95841.1 - 0.31 10.7 1.7 5.7 6.6 1.7 2.3 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger CDC27 PF09507.10 KFX95841.1 - 2.3 7.5 27.1 2.8 7.2 27.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 KFX95841.1 - 2.4 6.7 17.1 2.9 6.4 17.1 1.0 1 0 0 1 1 1 0 Hamartin protein CpXC PF14353.6 KFX95841.1 - 9.7 6.3 8.1 38 4.3 8.1 2.1 1 1 0 1 1 1 0 CpXC protein AAA PF00004.29 KFX95847.1 - 7.5e-39 133.2 0.0 2.3e-38 131.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX95847.1 - 3.4e-07 30.0 0.8 3.4e-07 30.0 0.8 2.3 2 0 0 2 2 2 1 AAA+ lid domain ABC_tran PF00005.27 KFX95847.1 - 7.2e-06 26.6 0.4 0.27 11.8 0.0 3.9 4 0 0 4 4 4 2 ABC transporter RuvB_N PF05496.12 KFX95847.1 - 8.3e-06 25.6 0.5 0.00016 21.4 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX95847.1 - 4.9e-05 22.7 0.1 0.00042 19.6 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 KFX95847.1 - 0.00023 21.5 0.3 0.011 16.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX95847.1 - 0.00024 21.6 1.4 0.0016 18.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KFX95847.1 - 0.00025 21.6 0.1 0.0047 17.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX95847.1 - 0.00038 20.5 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFX95847.1 - 0.00042 20.6 0.0 0.00098 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX95847.1 - 0.00073 19.7 0.0 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFX95847.1 - 0.0013 18.9 0.0 0.0099 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KFX95847.1 - 0.0024 17.3 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFX95847.1 - 0.0026 17.8 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KFX95847.1 - 0.0033 17.2 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX95847.1 - 0.0037 17.6 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFX95847.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 KFX95847.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KFX95847.1 - 0.033 14.1 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KFX95847.1 - 0.034 13.6 0.1 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 KFX95847.1 - 0.041 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFX95847.1 - 0.045 13.2 0.0 0.28 10.6 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein DUF815 PF05673.13 KFX95847.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 KFX95847.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KFX95847.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4050 PF13259.6 KFX95848.1 - 1.8e-43 149.0 3.0 1.8e-43 149.0 3.0 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) DUF2514 PF10721.9 KFX95849.1 - 0.053 13.6 6.3 0.07 13.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF3340 PF11818.8 KFX95849.1 - 0.054 13.7 2.1 0.068 13.3 2.1 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Mus7 PF09462.10 KFX95853.1 - 8.2e-58 196.7 0.0 1.2e-57 196.2 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Cys_Met_Meta_PP PF01053.20 KFX95854.1 - 6.1e-57 192.9 0.0 1.2e-56 191.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX95854.1 - 0.00018 20.8 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX95854.1 - 0.035 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V FMN_bind_2 PF04299.12 KFX95855.1 - 1.8e-58 196.9 0.0 2.2e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.8 KFX95856.1 - 8.2e-47 159.8 7.6 1e-46 159.5 7.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.28 KFX95865.1 - 3.6e-08 33.5 0.0 1e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Acylphosphatase PF00708.18 KFX95867.1 - 7.1e-20 71.2 0.9 7.9e-20 71.1 0.9 1.0 1 0 0 1 1 1 1 Acylphosphatase Ank_2 PF12796.7 KFX95868.1 - 6.3e-28 97.2 0.3 2.9e-12 47.0 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95868.1 - 4.4e-21 75.0 0.1 5.1e-07 30.1 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFX95868.1 - 7.6e-17 60.9 0.0 0.0016 18.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFX95868.1 - 4.9e-15 54.1 0.1 0.017 15.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFX95868.1 - 3.4e-14 52.7 0.8 4.1e-06 26.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF2232 PF09991.9 KFX95868.1 - 0.033 13.4 0.2 0.048 12.8 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Glyco_hydro_12 PF01670.16 KFX95869.1 - 1.2e-43 149.6 11.1 1.4e-43 149.4 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 KFX95869.1 - 0.99 9.8 4.9 0.62 10.5 1.6 2.3 1 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 FAA_hydrolase PF01557.18 KFX95870.1 - 6.6e-53 179.6 0.0 7.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hep_59 PF07052.11 KFX95883.1 - 5.5e-09 36.7 0.0 9.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Pkinase PF00069.25 KFX95892.1 - 1.1e-63 215.1 0.0 1.3e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95892.1 - 1.6e-30 106.3 0.0 2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX95892.1 - 4.7e-05 22.8 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFX95892.1 - 0.0042 17.0 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFX95892.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFX95892.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KFX95892.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFX95892.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S8 PF00082.22 KFX95894.1 - 7.4e-34 117.4 10.4 9e-34 117.1 9.2 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFX95894.1 - 1.1e-19 70.9 0.2 2.9e-19 69.5 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 KFX95895.1 - 3.6e-117 390.7 0.1 7.9e-117 389.5 0.1 1.6 1 0 0 1 1 1 1 Beige/BEACH domain HLH PF00010.26 KFX95895.1 - 3.1e-16 59.1 0.3 9e-16 57.6 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Laminin_G_3 PF13385.6 KFX95895.1 - 1.2e-10 41.8 0.1 2.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KFX95895.1 - 4e-09 36.5 0.0 1.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFX95895.1 - 0.00057 20.7 1.6 0.11 13.4 0.0 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF4704 PF15787.5 KFX95895.1 - 0.0049 16.1 0.0 0.049 12.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) FAD_binding_3 PF01494.19 KFX95896.1 - 7e-18 65.0 0.0 1.9e-17 63.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFX95896.1 - 1.9e-05 24.1 0.4 0.0049 16.2 0.3 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KFX95896.1 - 0.00099 18.4 0.3 0.098 11.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX95896.1 - 0.0041 16.4 0.0 0.095 11.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NnrS PF05940.12 KFX95896.1 - 0.0087 15.5 1.7 0.014 14.8 1.7 1.4 1 0 0 1 1 1 1 NnrS protein NAD_binding_8 PF13450.6 KFX95896.1 - 0.059 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX95896.1 - 0.11 11.5 0.2 0.56 9.2 0.2 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KFX95896.1 - 2.8 8.6 3.7 18 6.0 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.13 KFX95898.1 - 1e-70 237.6 2.3 1.5e-70 237.0 2.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Class_IIIsignal PF04021.12 KFX95898.1 - 1.6 8.8 5.7 0.42 10.6 1.4 2.4 2 0 0 2 2 2 0 Class III signal peptide PhyH PF05721.13 KFX95899.1 - 8.3e-05 22.9 0.1 0.00022 21.6 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 KFX95900.1 - 6.3e-38 130.6 26.9 6.3e-38 130.6 26.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_7_1 PF16081.5 KFX95900.1 - 2.3 8.4 6.0 0.38 10.9 1.3 2.1 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF4006 PF13179.6 KFX95900.1 - 5.2 7.1 5.4 5.8 6.9 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF4006) SLC35F PF06027.12 KFX95901.1 - 9e-102 340.6 25.0 1.1e-101 340.4 25.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KFX95901.1 - 2e-10 40.1 5.3 3.8e-10 39.2 5.3 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KFX95901.1 - 2.4e-06 27.8 39.1 0.0037 17.4 15.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Tim17 PF02466.19 KFX95901.1 - 0.62 10.5 3.8 0.62 10.5 0.9 2.3 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_64 PF16483.5 KFX95902.1 - 1.5e-121 406.2 0.0 1.7e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF3383 PF11863.8 KFX95902.1 - 0.09 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Methyltransf_23 PF13489.6 KFX95903.1 - 6.2e-13 48.9 0.1 1.7e-12 47.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX95903.1 - 6.6e-09 36.4 0.0 1.9e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX95903.1 - 4.8e-05 24.0 0.0 0.00042 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX95903.1 - 6.8e-05 22.7 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95903.1 - 7.2e-05 23.4 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX95903.1 - 0.0065 15.8 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KFX95903.1 - 0.042 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KFX95903.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 KFX95903.1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.12 KFX95903.1 - 0.081 12.4 0.3 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase HD PF01966.22 KFX95904.1 - 4.8e-08 33.2 0.3 6e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 HD domain Pkinase PF00069.25 KFX95906.1 - 2.6e-08 33.5 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX95906.1 - 0.00017 21.6 0.1 0.00026 21.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX95906.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX95906.1 - 0.066 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFX95906.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFX95906.1 - 0.2 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mito_carr PF00153.27 KFX95915.1 - 2.2e-66 219.8 6.3 3.8e-22 78.0 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFX95915.1 - 2.5e-19 69.5 1.5 1.9e-08 34.7 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KFX95915.1 - 3.5e-19 66.9 7.1 6.3e-06 25.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KFX95915.1 - 1.2e-16 59.1 7.8 0.00066 19.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX95915.1 - 4.9e-15 54.2 9.0 2.3e-06 26.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFX95915.1 - 1.4e-12 47.3 4.1 1.4e-06 28.1 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFX95915.1 - 1e-05 25.8 0.0 0.16 12.3 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFX95915.1 - 0.0019 18.5 0.5 0.81 10.1 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain Cyclin_N PF00134.23 KFX95916.1 - 1.6e-10 40.8 1.1 2.3e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFX95916.1 - 0.035 14.5 0.5 0.1 13.0 0.2 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain Turandot PF07240.11 KFX95916.1 - 0.11 12.5 0.6 0.24 11.4 0.3 1.7 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot ANAPC4_WD40 PF12894.7 KFX95919.1 - 0.13 12.6 0.0 3.3 8.1 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX95919.1 - 0.13 13.2 0.0 1.2 10.1 0.0 2.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Cupin_8 PF13621.6 KFX95920.1 - 1.7e-33 116.4 0.0 2.8e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KFX95920.1 - 1e-21 77.7 0.0 1.7e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KFX95920.1 - 4.6e-17 61.7 6.8 1.1e-06 28.5 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFX95920.1 - 3.7e-08 33.2 0.0 9.5e-05 22.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KFX95920.1 - 7.6e-07 29.2 4.5 0.0061 16.8 0.0 3.5 2 1 1 3 3 3 2 Kelch motif Cupin_4 PF08007.12 KFX95920.1 - 2.7e-05 23.8 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 KFX95920.1 - 0.00076 19.7 1.7 0.14 12.5 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KFX95920.1 - 0.011 15.3 3.7 0.24 11.0 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 KFX95920.1 - 0.026 14.5 6.8 0.083 12.9 0.2 3.8 4 0 0 4 4 4 0 Kelch motif PX PF00787.24 KFX95931.1 - 3.9e-14 52.6 0.0 5.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 PX domain GST_C PF00043.25 KFX95933.1 - 1.1e-08 35.1 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX95933.1 - 3e-08 33.6 0.0 4.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX95933.1 - 9.4e-08 32.2 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFX95933.1 - 0.0053 17.3 0.0 0.0077 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BP28CT PF08146.12 KFX95934.1 - 4.1e-39 134.0 2.2 6.5e-39 133.3 0.2 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KFX95934.1 - 7.9e-28 97.1 3.9 2.3e-27 95.6 0.0 4.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KFX95934.1 - 0.00095 19.2 9.6 0.22 11.9 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat EF-hand_4 PF12763.7 KFX95934.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HEAT_2 PF13646.6 KFX95934.1 - 0.11 12.9 16.7 0.19 12.1 2.0 5.9 5 0 0 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 KFX95934.1 - 0.39 11.3 10.9 4.9 7.8 0.1 6.2 4 2 0 4 4 4 0 HEAT-like repeat Zip PF02535.22 KFX95941.1 - 2e-65 221.2 5.8 2.3e-65 221.0 5.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.25 KFX95942.1 - 8.4e-46 156.5 0.0 1.8e-45 155.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95942.1 - 1.2e-30 106.6 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX95942.1 - 0.0011 17.8 0.0 0.0022 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KFX95942.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX95942.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Peroxidase_2 PF01328.17 KFX95943.1 - 2.6e-48 165.1 0.0 3.3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.18 KFX95944.1 - 2.8e-09 36.9 10.1 4.9e-09 36.2 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX95944.1 - 6.3e-07 28.5 0.1 8.8e-07 28.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_28 PF00295.17 KFX95946.1 - 2.5e-35 122.1 10.2 3.5e-35 121.6 10.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFX95946.1 - 1.3 8.8 20.9 0.028 14.3 12.0 2.5 2 1 0 3 3 3 0 Right handed beta helix region COesterase PF00135.28 KFX95947.1 - 8.5e-76 255.9 0.0 1e-75 255.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX95947.1 - 3.3e-07 30.4 0.0 1.4e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX95947.1 - 0.027 13.9 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sulfakinin PF08257.11 KFX95947.1 - 0.19 11.8 0.9 0.62 10.3 0.9 1.9 1 0 0 1 1 1 0 Sulfakinin family FAD_binding_4 PF01565.23 KFX95948.1 - 1.9e-21 76.2 2.7 5.1e-21 74.9 2.7 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX95948.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.24 KFX95950.1 - 7e-79 265.8 21.7 8.1e-79 265.6 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95950.1 - 6.9e-38 130.5 49.9 3e-31 108.6 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX95950.1 - 0.0012 17.4 0.6 0.0025 16.3 0.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2463 PF09591.10 KFX95950.1 - 0.014 15.2 0.4 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Glyco_hydro_88 PF07470.13 KFX95951.1 - 8.1e-10 38.3 0.2 1.5e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.9 KFX95952.1 - 4.8e-127 423.9 0.1 5.8e-127 423.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.18 KFX95953.1 - 6e-15 55.0 0.1 1.9e-14 53.4 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95953.1 - 2.1e-06 27.7 10.9 3.6e-06 27.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1749 PF08538.10 KFX95955.1 - 2.6e-98 328.8 0.0 3.2e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KFX95955.1 - 0.00092 19.9 0.0 0.0016 19.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX95955.1 - 0.001 18.7 0.1 0.0021 17.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFX95955.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KFX95955.1 - 0.041 13.1 0.0 0.093 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 KFX95956.1 - 1.6e-69 234.5 0.0 1.8e-65 221.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KFX95956.1 - 7.2e-68 229.3 0.0 3.2e-37 128.3 0.0 2.7 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KFX95956.1 - 1.3e-23 83.1 0.1 7.8e-12 45.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX95956.1 - 0.0036 18.2 0.0 5.5 8.1 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KFX95957.1 - 4.3e-23 81.8 56.0 2.9e-15 56.0 32.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX95957.1 - 9.2e-09 34.3 29.4 1.2e-08 33.9 28.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH_1 PF00378.20 KFX95958.1 - 5.9e-54 183.0 0.0 8e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX95958.1 - 5.7e-30 104.9 1.1 1.1e-25 90.9 0.3 2.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Acetyltransf_8 PF13523.6 KFX95959.1 - 2.1e-41 141.0 0.1 2.9e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 KFX95960.1 - 4.3e-91 305.4 27.0 1.1e-47 163.0 5.8 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX95960.1 - 3.1e-62 209.1 0.0 6.1e-31 107.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX95960.1 - 1.3e-14 54.2 3.0 0.00081 18.9 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX95960.1 - 4e-09 37.1 1.6 0.0043 17.4 0.2 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFX95960.1 - 2.9e-08 33.3 1.5 0.0014 18.3 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KFX95960.1 - 5e-08 33.3 1.1 0.00013 22.1 0.2 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 KFX95960.1 - 8.6e-08 32.5 1.0 0.17 12.2 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX95960.1 - 1.6e-05 24.7 4.7 0.038 13.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KFX95960.1 - 5.7e-05 23.1 0.0 0.073 13.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KFX95960.1 - 0.00013 22.5 0.3 0.15 12.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KFX95960.1 - 0.00028 19.8 0.2 0.077 11.8 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KFX95960.1 - 0.0006 19.7 2.7 0.21 11.4 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFX95960.1 - 0.0015 18.9 1.5 9.3 6.7 0.3 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFX95960.1 - 0.002 17.7 0.3 1.8 8.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KFX95960.1 - 0.0024 18.4 0.0 3.3 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX95960.1 - 0.0033 17.6 0.2 2.7 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KFX95960.1 - 0.0042 16.2 0.0 0.37 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_15 PF13175.6 KFX95960.1 - 0.0058 16.4 0.1 0.58 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KFX95960.1 - 0.012 15.5 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 KFX95960.1 - 0.013 15.2 0.9 19 4.9 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KFX95960.1 - 0.022 14.0 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KFX95960.1 - 0.025 14.8 1.0 4.7 7.5 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KFX95960.1 - 0.028 14.4 0.0 6.2 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFX95960.1 - 0.032 14.3 0.1 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KFX95960.1 - 0.048 13.4 0.1 2.1 8.1 0.0 2.9 3 1 0 3 3 3 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KFX95960.1 - 0.055 12.7 0.0 13 4.9 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 KFX95960.1 - 0.055 13.1 0.2 13 5.3 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KFX95960.1 - 0.081 12.4 0.1 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 KFX95960.1 - 0.13 11.4 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KFX95960.1 - 0.14 11.5 0.1 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFX95960.1 - 0.2 11.3 0.3 12 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFX95960.1 - 0.26 11.7 0.6 29 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain TIM PF00121.18 KFX95963.1 - 4.2e-89 298.1 0.4 4.8e-89 297.9 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.16 KFX95964.1 - 7.8e-15 54.5 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KFX95965.1 - 2.3e-26 92.3 3.6 2.3e-26 92.3 3.6 2.2 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KFX95965.1 - 2.8e-17 62.3 0.3 1.1e-16 60.3 0.3 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX95965.1 - 4.7e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif UreD PF01774.17 KFX95966.1 - 1.8e-74 250.3 0.1 2.1e-74 250.0 0.1 1.0 1 0 0 1 1 1 1 UreD urease accessory protein DUF1155 PF06633.11 KFX95966.1 - 0.066 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) STAG PF08514.11 KFX95967.1 - 1.3e-31 108.8 0.3 5.7e-31 106.8 0.3 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KFX95967.1 - 0.00023 21.5 0.0 0.022 15.1 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KFX95967.1 - 0.0041 17.2 0.9 26 5.5 0.1 4.8 6 0 0 6 6 6 2 HEAT repeat Methyltransf_23 PF13489.6 KFX95968.1 - 3.1e-14 53.2 0.0 4.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX95968.1 - 1.5e-09 38.4 0.0 6.5e-09 36.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95968.1 - 3.4e-06 27.6 0.0 6.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFX95968.1 - 0.00058 19.7 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 KFX95968.1 - 0.00075 18.9 0.0 0.93 8.8 0.0 2.5 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFX95968.1 - 0.0032 17.3 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFX95968.1 - 0.0041 17.8 0.0 0.024 15.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFX95968.1 - 0.0042 17.0 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Chromo PF00385.24 KFX95970.1 - 8.7e-17 60.8 4.0 8.4e-08 32.0 0.4 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_6 PF13921.6 KFX95970.1 - 0.0001 22.5 0.4 0.00034 20.8 0.4 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX95970.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mtf2_C PF14061.6 KFX95970.1 - 0.29 11.3 1.4 8.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 EGF_Tenascin PF18720.1 KFX95970.1 - 6.5 6.9 6.3 2.5 8.2 0.9 2.6 2 0 0 2 2 2 0 Tenascin EGF domain KASH_CCD PF14662.6 KFX95971.1 - 2.8 7.7 12.7 5.3 6.8 12.7 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PAH PF02671.21 KFX95973.1 - 4.2e-10 39.6 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat ANAPC1 PF12859.7 KFX95973.1 - 0.098 13.2 2.8 0.21 12.2 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF3723 PF12520.8 KFX95974.1 - 1.1e-146 489.5 0.0 8.4e-135 450.3 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) RR_TM4-6 PF06459.12 KFX95974.1 - 1.7 8.4 9.1 3 7.6 9.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 KFX95974.1 - 8.3 6.4 13.4 17 5.4 13.4 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.25 KFX95975.1 - 6.5e-05 22.4 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95975.1 - 8.3e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_ligase_A_N PF04675.14 KFX95983.1 - 5.7e-17 62.6 0.0 8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus DUF4048 PF13257.6 KFX95984.1 - 5.3e-16 59.2 31.2 8.6e-16 58.5 6.2 4.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) Ribosomal_L29 PF00831.23 KFX95984.1 - 0.34 10.9 4.2 0.62 10.1 4.2 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein Tim17 PF02466.19 KFX95985.1 - 7.6e-38 129.3 6.8 7.6e-38 129.3 6.8 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SKIP_SNW PF02731.15 KFX95986.1 - 2.1e-72 242.0 5.9 2.1e-72 242.0 5.9 2.3 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.24 KFX95986.1 - 3.6e-44 150.9 3.5 3.6e-44 150.9 3.5 1.8 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD IMUP PF15761.5 KFX95986.1 - 0.2 12.3 7.7 0.82 10.4 7.5 2.2 1 1 0 1 1 1 0 Immortalisation up-regulated protein Innexin PF00876.18 KFX95986.1 - 0.21 10.8 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 Innexin 7tm_1 PF00001.21 KFX95986.1 - 0.33 10.2 0.7 0.46 9.8 0.1 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4603 PF15376.6 KFX95986.1 - 7.6 3.8 16.0 12 3.2 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) USP7_ICP0_bdg PF12436.8 KFX95987.1 - 2.5e-83 279.1 0.4 8.2e-82 274.1 0.2 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFX95987.1 - 1.9e-75 253.1 5.0 7.4e-73 244.6 0.3 3.7 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFX95987.1 - 1.2e-46 159.3 1.3 2.1e-46 158.5 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX95987.1 - 1.9e-20 73.7 0.4 1.9e-20 73.7 0.4 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFX95987.1 - 2.6e-09 37.2 0.5 1.3e-08 34.9 0.2 2.3 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 KFX95987.1 - 0.0029 17.3 0.0 25 4.7 0.0 5.1 5 0 0 5 5 5 0 Ubiquitin family YukD PF08817.10 KFX95987.1 - 0.013 16.2 0.0 0.61 10.8 0.0 2.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF3601 PF12208.8 KFX95987.1 - 0.091 12.9 0.2 0.31 11.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) BCDHK_Adom3 PF10436.9 KFX95988.1 - 2.6e-49 167.2 0.4 5.5e-49 166.1 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFX95988.1 - 1.2e-06 29.0 0.0 3.5e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFX95988.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2688 PF10892.8 KFX95988.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Septin PF00735.18 KFX95989.1 - 2.3e-113 378.2 0.1 2.3e-113 378.2 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFX95989.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX95989.1 - 3.1e-06 26.9 1.5 0.00011 21.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX95989.1 - 5.1e-06 26.5 0.0 5.8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFX95989.1 - 0.0022 18.3 0.7 0.0068 16.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KFX95989.1 - 0.0029 17.1 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KFX95989.1 - 0.0037 17.5 0.1 0.0076 16.5 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KFX95989.1 - 0.006 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KFX95989.1 - 0.0082 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 KFX95989.1 - 0.014 15.1 7.1 0.034 13.8 7.1 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 KFX95989.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX95989.1 - 0.026 14.9 0.5 0.077 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 KFX95989.1 - 0.029 14.0 0.3 0.086 12.4 0.3 1.8 1 1 0 1 1 1 0 Ras family T2SSE PF00437.20 KFX95989.1 - 0.038 13.1 0.3 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 KFX95989.1 - 0.041 14.4 0.1 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 KFX95989.1 - 0.046 13.0 0.0 0.051 12.8 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 KFX95989.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 KFX95989.1 - 0.064 13.9 0.5 0.23 12.1 0.5 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain Sigma54_activat PF00158.26 KFX95989.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 KFX95989.1 - 0.16 11.7 0.3 5.3 6.8 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KFX95989.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 KFX95989.1 - 0.27 11.0 0.7 13 5.4 0.1 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KFX95989.1 - 0.45 10.5 4.9 4.6 7.3 0.0 2.8 2 1 1 3 3 3 0 Dynamin family Adaptin_binding PF10199.9 KFX95989.1 - 1.8 9.2 5.6 2.9 8.5 5.6 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 WD40 PF00400.32 KFX95990.1 - 8.8e-43 143.5 29.2 3.9e-09 37.0 0.3 13.6 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 KFX95990.1 - 1.7e-25 89.4 0.0 2.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFX95990.1 - 6.9e-23 80.8 0.0 0.038 14.3 0.0 9.8 4 1 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX95990.1 - 4.7e-09 35.7 0.2 0.8 8.6 0.0 5.5 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX95990.1 - 2e-07 31.1 4.0 0.068 13.0 0.2 5.7 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFX95990.1 - 0.00011 21.7 0.0 1.8 7.8 0.0 3.6 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 KFX95990.1 - 0.0036 16.0 4.6 2.3 6.8 0.1 3.9 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFX95990.1 - 0.018 13.6 0.0 1.4 7.4 0.0 3.3 4 1 0 4 4 4 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KFX95990.1 - 0.031 13.6 0.1 3.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KFX95990.1 - 0.055 12.4 0.0 4.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KFX95990.1 - 0.096 13.2 3.7 25 5.5 0.3 5.0 5 0 0 5 5 4 0 PQQ-like domain TPR_2 PF07719.17 KFX95996.1 - 4.1e-33 110.8 1.3 2.3e-05 24.1 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX95996.1 - 9.1e-32 109.1 7.4 9.6e-25 86.6 0.1 5.5 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFX95996.1 - 1.2e-28 97.7 0.0 1.1e-05 25.0 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFX95996.1 - 2.5e-25 88.8 1.7 0.0018 18.7 0.0 7.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95996.1 - 5.8e-24 82.3 0.0 0.0036 17.4 0.1 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFX95996.1 - 6e-24 84.1 4.7 1.8e-10 40.9 0.0 8.4 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX95996.1 - 4.4e-18 65.6 0.9 9.3e-07 29.4 0.0 7.5 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX95996.1 - 1.1e-17 63.2 2.6 0.0035 18.0 0.0 9.3 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX95996.1 - 1.8e-16 58.9 4.0 1.3e-05 24.8 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX95996.1 - 1.3e-14 53.5 1.6 9.5e-07 28.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX95996.1 - 5.6e-14 51.5 0.1 3.2e-05 23.5 0.0 6.9 6 2 1 7 7 7 2 TPR repeat TPR_6 PF13174.6 KFX95996.1 - 2.4e-13 49.7 2.7 0.061 14.0 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFX95996.1 - 2.6e-09 36.8 0.3 0.0095 16.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX95996.1 - 1.2e-08 34.9 0.4 0.0017 18.4 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFX95996.1 - 6.1e-05 22.4 0.1 1.5 8.0 0.0 4.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX95996.1 - 0.00025 21.2 0.2 46 4.7 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX95996.1 - 0.00027 20.4 3.4 0.025 14.0 0.1 4.4 4 2 0 5 5 4 1 MalT-like TPR region DUF3856 PF12968.7 KFX95996.1 - 0.00036 20.6 0.4 0.086 12.9 0.0 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) PPR PF01535.20 KFX95996.1 - 0.001 19.2 4.9 0.23 11.8 0.1 4.5 4 0 0 4 4 4 1 PPR repeat SRP_TPR_like PF17004.5 KFX95996.1 - 0.0011 18.9 0.1 0.4 10.7 0.0 3.4 3 1 1 4 4 4 1 Putative TPR-like repeat RPN7 PF10602.9 KFX95996.1 - 0.0023 17.7 0.1 2.1 8.1 0.0 4.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 HrpB1_HrpK PF09613.10 KFX95996.1 - 0.003 17.2 0.0 11 5.7 0.0 4.2 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_5 PF12688.7 KFX95996.1 - 0.037 14.3 0.2 0.49 10.7 0.0 3.0 4 0 0 4 4 2 0 Tetratrico peptide repeat TPR_21 PF09976.9 KFX95996.1 - 0.041 13.6 5.2 9.2 5.9 0.2 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat-like domain Ribosomal_L27 PF01016.19 KFX95997.1 - 1.2e-31 108.5 0.1 3.1e-31 107.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA-synt_1c PF00749.21 KFX95999.1 - 5.5e-105 350.7 0.1 7.2e-105 350.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFX95999.1 - 2.3e-39 135.0 0.1 4e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KFX95999.1 - 0.015 14.6 0.5 0.044 13.1 0.2 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF3673 PF12425.8 KFX95999.1 - 0.12 12.3 0.2 14 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) Ribosomal_L1 PF00687.21 KFX96000.1 - 4.7e-31 108.1 0.0 8e-31 107.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family FlgT_C PF16538.5 KFX96000.1 - 0.09 13.3 0.2 5 7.7 0.1 2.4 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain COG2 PF06148.11 KFX96001.1 - 8.6e-29 100.3 0.7 1.5e-28 99.5 0.7 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KFX96001.1 - 1.9e-05 24.6 0.6 0.00052 20.0 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 KFX96001.1 - 0.00026 20.0 0.5 0.00036 19.5 0.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein COG5 PF10392.9 KFX96001.1 - 0.051 13.8 0.2 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.11 KFX96001.1 - 0.062 13.9 1.5 4.4 7.9 0.0 2.7 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Hap4_Hap_bind PF10297.9 KFX96002.1 - 7.5e-06 25.9 9.4 7.5e-06 25.9 9.4 3.1 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KFX96002.1 - 0.0036 17.3 12.9 0.0036 17.3 12.9 2.0 2 1 0 2 2 2 1 bZIP transcription factor APC_N_CC PF16689.5 KFX96002.1 - 0.12 12.5 3.0 0.26 11.4 3.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain dsrm PF00035.26 KFX96002.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF1664 PF07889.12 KFX96002.1 - 0.23 11.5 0.7 0.61 10.1 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 KFX96002.1 - 0.46 10.5 11.9 0.16 12.0 8.7 1.7 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Stathmin PF00836.19 KFX96002.1 - 0.73 9.8 13.1 1.6 8.7 13.1 1.5 1 0 0 1 1 1 0 Stathmin family Spc7 PF08317.11 KFX96002.1 - 1.8 7.3 13.1 3 6.6 13.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Adaptin_binding PF10199.9 KFX96002.1 - 3.1 8.4 9.9 8.5 7.0 9.9 1.7 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF4407 PF14362.6 KFX96002.1 - 5.2 6.3 6.5 9.1 5.5 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_2 PF07719.17 KFX96003.1 - 0.00024 21.0 0.0 0.24 11.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 KFX96003.1 - 0.0098 15.8 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_8 PF13181.6 KFX96003.1 - 0.029 14.6 0.1 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX96003.1 - 0.037 14.3 0.0 0.76 10.1 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX96003.1 - 0.13 12.1 0.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KFX96003.1 - 0.2 11.8 1.6 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 DnaJ domain PhoD PF09423.10 KFX96004.1 - 5.2e-42 144.1 0.0 1.2e-41 142.9 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase SGS PF05002.15 KFX96004.1 - 2e-32 111.1 1.5 4.2e-32 110.1 1.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KFX96004.1 - 1.8e-16 60.9 0.1 5.2e-16 59.4 0.1 1.9 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KFX96004.1 - 0.0032 17.5 4.7 3.6 7.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX96004.1 - 0.025 14.4 4.5 2.8 7.9 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1627 PF07789.12 KFX96004.1 - 0.052 13.2 0.3 9.7 5.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) DUF2057 PF09829.9 KFX96004.1 - 0.22 11.7 2.4 5.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_19 PF14559.6 KFX96004.1 - 0.82 10.2 3.9 1 9.9 1.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX96004.1 - 3.9 7.8 11.7 3.4 8.0 2.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFX96005.1 - 1.7e-69 234.1 0.0 2.7e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96005.1 - 5.4e-46 157.0 0.0 1.2e-45 155.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX96005.1 - 8.8e-06 24.7 0.2 2.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFX96005.1 - 0.00017 21.0 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like hNIFK_binding PF12196.8 KFX96005.1 - 0.14 11.7 2.6 0.4 10.2 2.6 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK YABBY PF04690.13 KFX96005.1 - 3.2 8.3 5.3 0.39 11.3 0.3 1.9 2 0 0 2 2 2 0 YABBY protein MAJIN PF15077.6 KFX96005.1 - 5.1 6.8 6.7 2 8.2 0.9 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein Transglut_core PF01841.19 KFX96006.1 - 4e-12 46.6 0.1 1.3e-11 45.0 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KFX96006.1 - 4.2e-09 35.9 0.1 2e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFX96006.1 - 7.1e-06 25.5 0.0 2.9e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX96006.1 - 0.024 14.5 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain Transglut_core2 PF13369.6 KFX96006.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily UQ_con PF00179.26 KFX96007.1 - 2.4e-50 169.8 0.0 2.7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX96007.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B NMT1 PF09084.11 KFX96008.1 - 9.1e-06 25.8 0.0 2.6e-05 24.3 0.0 1.7 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_3 PF16868.5 KFX96008.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family ATP-synt_ab PF00006.25 KFX96009.1 - 4.8e-109 363.0 0.0 7.1e-109 362.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KFX96009.1 - 2e-46 156.8 0.0 4e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KFX96009.1 - 3.6e-15 56.2 4.9 7.4e-15 55.2 4.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain WD40 PF00400.32 KFX96010.1 - 5e-28 96.8 11.8 2.2e-05 25.1 0.3 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96010.1 - 5.9e-16 58.5 0.2 0.13 12.6 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX96010.1 - 8.2e-05 22.6 0.2 0.34 10.8 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.9 KFX96010.1 - 0.0032 17.4 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_3 PF15911.5 KFX96010.1 - 0.0078 16.2 0.0 0.78 9.8 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat PD40 PF07676.12 KFX96010.1 - 0.0091 15.9 0.3 77 3.4 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFX96010.1 - 0.026 13.2 0.1 0.27 9.8 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFX96010.1 - 0.17 10.8 0.1 2.9 6.8 0.1 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PfkB PF00294.24 KFX96011.1 - 8.4e-51 173.1 1.1 1e-50 172.8 1.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Dynamin_M PF01031.20 KFX96012.1 - 7.3e-101 337.1 0.2 1.5e-100 336.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFX96012.1 - 3.1e-56 190.0 0.0 5.8e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFX96012.1 - 1.5e-30 105.2 6.1 3.2e-30 104.1 6.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFX96012.1 - 6.1e-05 23.1 0.4 0.00043 20.3 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFX96012.1 - 0.014 15.1 0.6 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain CoA_transf_3 PF02515.17 KFX96013.1 - 3.5e-68 230.4 0.0 4.5e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Tudor_2 PF18104.1 KFX96013.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Exo_endo_phos PF03372.23 KFX96014.1 - 2.2e-11 43.7 0.3 5.8e-11 42.3 0.2 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF1572 PF07609.11 KFX96014.1 - 0.071 12.9 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) BBS2_Mid PF14783.6 KFX96014.1 - 0.11 12.6 0.1 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF4748 PF15932.5 KFX96015.1 - 4.7e-24 83.9 0.4 7.3e-24 83.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Rav1p_C PF12234.8 KFX96015.1 - 0.097 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal CTD_bind PF04818.13 KFX96016.1 - 1.7e-14 54.3 0.4 6.5e-14 52.5 0.4 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RSRP PF17069.5 KFX96016.1 - 0.00046 19.9 27.4 0.00089 18.9 27.4 1.4 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 DIL PF01843.19 KFX96016.1 - 0.037 14.3 0.4 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 DIL domain Apt1 PF10351.9 KFX96016.1 - 0.055 12.3 4.6 0.097 11.5 4.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Transformer PF06495.11 KFX96016.1 - 0.87 9.7 33.9 0.23 11.5 30.6 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein PRP38_assoc PF12871.7 KFX96016.1 - 1.1 9.9 38.3 0.093 13.3 33.4 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GCP_N_terminal PF17681.1 KFX96021.1 - 2e-28 99.9 0.0 2.9e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFX96021.1 - 1.5e-24 87.0 0.0 4.6e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KFX96021.1 - 0.00028 19.4 0.0 0.00077 17.9 0.0 1.6 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 AF-4 PF05110.13 KFX96021.1 - 0.13 10.3 1.7 0.2 9.7 1.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_transf_15 PF01793.16 KFX96022.1 - 4.3e-111 371.3 6.7 6.1e-111 370.8 6.7 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Aminotran_1_2 PF00155.21 KFX96022.1 - 5.5e-13 48.8 0.0 2.1e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.11 KFX96022.1 - 0.006 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Tannase and feruloyl esterase MTHFR PF02219.17 KFX96023.1 - 1e-102 343.4 0.0 1.4e-102 342.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cdc6_C PF09079.11 KFX96028.1 - 0.084 12.9 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain VHS PF00790.19 KFX96037.1 - 7e-33 113.4 1.6 1.4e-32 112.5 1.6 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KFX96037.1 - 2.7e-16 58.9 0.0 5.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX96037.1 - 1.3e-14 53.7 0.0 2.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX96037.1 - 7e-14 51.3 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KFX96037.1 - 1.2e-09 38.3 3.3 1.5e-09 38.0 0.5 2.4 3 0 0 3 3 3 1 GAT domain UIM PF02809.20 KFX96037.1 - 0.044 13.7 2.9 0.11 12.5 2.9 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3361 PF11841.8 KFX96037.1 - 0.082 12.8 0.8 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) PEP-utilisers_N PF05524.13 KFX96037.1 - 2.3 8.4 6.1 0.68 10.1 0.6 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Cyt-b5 PF00173.28 KFX96038.1 - 5.4e-23 80.9 0.1 7.2e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.17 KFX96039.1 - 1.7e-96 322.8 0.0 1.9e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit MBA1 PF07961.11 KFX96049.1 - 4e-18 65.3 0.0 5.1e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KFX96049.1 - 2.6e-08 34.1 0.2 7.9e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Tim44-like domain SSF PF00474.17 KFX96050.1 - 1.5e-05 24.0 31.3 0.00013 21.0 31.3 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.22 KFX96051.1 - 9.3e-26 89.5 0.8 4.1e-12 45.8 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX96051.1 - 0.0011 18.5 0.0 0.092 12.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFX96051.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_7 PF16367.5 KFX96051.1 - 0.0061 16.7 0.0 0.82 9.8 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFX96051.1 - 0.0064 16.5 0.2 0.21 11.6 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KFX96051.1 - 0.086 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain PORR PF11955.8 KFX96051.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain CIA30 PF08547.12 KFX96052.1 - 3.2e-44 150.8 0.0 5.7e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ANAPC5 PF12862.7 KFX96052.1 - 3.4e-34 116.8 2.2 9.6e-34 115.3 2.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KFX96052.1 - 0.011 16.2 5.2 1 9.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PMAIP1 PF15150.6 KFX96052.1 - 0.12 12.3 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced DUF719 PF05334.13 KFX96052.1 - 0.3 11.3 1.4 0.52 10.5 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) TPR_2 PF07719.17 KFX96052.1 - 0.32 11.2 4.6 21 5.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX96052.1 - 2.8 7.9 6.5 0.85 9.6 0.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat COX6A PF02046.15 KFX96053.1 - 5.7e-52 174.9 2.3 7e-52 174.6 2.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ESSS PF10183.9 KFX96053.1 - 0.023 14.9 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4091 PF13320.6 KFX96053.1 - 0.024 14.8 1.9 0.048 13.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Exo_endo_phos PF03372.23 KFX96054.1 - 3.7e-16 59.3 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KFX96054.1 - 6.8e-05 22.9 2.1 0.00019 21.4 2.1 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KFX96054.1 - 0.022 14.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HMG_box PF00505.19 KFX96055.1 - 2.4e-20 72.7 0.6 3.6e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX96055.1 - 0.026 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Peripla_BP_1 PF00532.21 KFX96056.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family ANTH PF07651.16 KFX96057.1 - 2e-79 266.5 0.0 2e-79 266.5 0.0 2.6 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KFX96057.1 - 1.3e-55 187.9 7.0 1.3e-55 187.9 7.0 6.6 4 2 2 6 6 6 3 I/LWEQ domain TcdB_N PF12918.7 KFX96057.1 - 0.035 14.4 4.7 0.068 13.5 1.9 3.3 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain DNA_pol_B PF00136.21 KFX96058.1 - 4.7e-98 328.9 0.0 6.3e-98 328.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFX96058.1 - 4.2e-22 78.7 0.0 1.4e-13 50.7 0.0 2.6 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFX96058.1 - 7.6e-18 64.7 6.4 1.8e-17 63.5 6.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MMM1 PF10296.9 KFX96058.1 - 1.1e-05 24.6 0.2 5.8e-05 22.3 0.0 2.2 2 1 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 DZR PF12773.7 KFX96058.1 - 3.7 7.7 4.7 3.1 7.9 1.0 1.7 1 1 1 2 2 2 0 Double zinc ribbon Slu7 PF11708.8 KFX96059.1 - 2.3e-74 250.6 18.4 2.3e-74 250.6 18.4 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFX96059.1 - 0.03 14.1 0.7 0.053 13.3 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 KFX96060.1 - 1.1e-11 44.2 1.1 1.1e-11 44.2 1.1 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KFX96060.1 - 3.5e-05 24.6 0.2 7e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KFX96060.1 - 0.086 13.0 0.4 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 KFX96061.1 - 3.9e-48 161.5 6.3 9e-47 157.1 5.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L21e DUF5486 PF17588.2 KFX96061.1 - 0.019 14.8 3.4 0.1 12.5 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Sec2p PF06428.11 KFX96062.1 - 6.9e-27 93.3 19.6 6.9e-27 93.3 19.6 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 KFX96062.1 - 0.36 9.7 18.4 1.1 8.0 14.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 KFX96062.1 - 0.36 11.1 9.2 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein ALMT PF11744.8 KFX96062.1 - 0.42 9.4 7.3 0.93 8.3 7.3 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.10 KFX96062.1 - 0.7 10.1 8.9 1.1 9.4 5.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5339 PF17274.2 KFX96062.1 - 1.7 9.6 11.9 50 4.9 0.0 3.5 2 1 0 2 2 2 0 Family of unknown function (DUF5339) V_ATPase_I PF01496.19 KFX96062.1 - 4.2 5.2 5.0 6.7 4.5 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Alg6_Alg8 PF03155.15 KFX96064.1 - 2.9e-150 501.5 20.0 3.3e-150 501.3 20.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 KFX96065.1 - 9.5e-21 74.2 0.0 1.5e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family MscS_porin PF12795.7 KFX96065.1 - 0.037 13.6 0.2 0.057 12.9 0.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Cornifin PF02389.15 KFX96065.1 - 0.065 13.4 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3498 PF12004.8 KFX96065.1 - 0.21 10.8 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) RVT_2 PF07727.14 KFX96087.1 - 3.9e-61 206.8 0.0 5.3e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KFX96087.1 - 0.1 12.4 0.4 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 Reverse transcriptase-like Retrotran_gag_2 PF14223.6 KFX96088.1 - 7.1e-14 51.6 0.2 2.3e-13 50.0 0.2 1.9 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFX96088.1 - 4.2e-10 39.9 0.3 9.1e-10 38.8 0.3 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KFX96088.1 - 2e-08 34.0 0.0 5.1e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain TFIIA PF03153.13 KFX96088.1 - 0.011 15.7 2.1 0.011 15.7 2.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 KFX96100.1 - 1.2e-10 41.1 0.0 2.3e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFX96100.1 - 8e-10 38.5 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX96100.1 - 2.7e-09 37.3 0.2 0.00038 20.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX96100.1 - 9.7e-05 21.8 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFX96100.1 - 0.0004 20.0 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFX96100.1 - 0.0028 16.5 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFX96100.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.21 KFX96101.1 - 2.8e-08 33.3 0.0 4.4e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KFX96102.1 - 1.4e-52 177.4 1.3 1.7e-52 177.1 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KFX96102.1 - 0.064 14.0 0.5 0.12 13.2 0.2 1.6 1 1 0 1 1 1 0 Pullulanase N1-terminal domain TFIIA_gamma_N PF02268.16 KFX96102.1 - 0.21 11.6 1.6 4.6 7.3 0.2 2.5 1 1 1 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Maf1 PF09174.10 KFX96103.1 - 4.1e-60 202.9 0.0 5.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator NOA36 PF06524.12 KFX96103.1 - 0.55 9.5 4.8 0.74 9.1 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L7Ae PF01248.26 KFX96104.1 - 4.9e-26 90.3 0.1 5.7e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFX96104.1 - 0.00032 20.8 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFX96104.1 - 0.0022 17.9 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 KFX96105.1 - 8.1e-35 119.0 32.4 2.6e-22 78.9 13.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CMD PF02627.20 KFX96106.1 - 1.4e-09 37.9 0.1 2e-07 31.0 0.0 2.5 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.21 KFX96108.1 - 1.9e-08 34.3 7.8 3.6e-08 33.4 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX96108.1 - 0.0057 16.7 8.0 0.0057 16.7 8.0 1.6 2 0 0 2 2 1 1 Basic region leucine zipper V_ATPase_I PF01496.19 KFX96108.1 - 0.012 13.6 1.0 0.013 13.5 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHE3 PF17078.5 KFX96108.1 - 0.057 13.1 5.5 0.1 12.3 5.4 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 KFX96108.1 - 0.13 12.8 9.1 0.27 11.8 9.1 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 KFX96108.1 - 0.13 11.5 2.9 0.16 11.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 KFX96108.1 - 0.15 11.6 4.6 0.2 11.2 4.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GAS PF13851.6 KFX96108.1 - 0.17 11.2 8.0 0.29 10.5 8.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KFX96108.1 - 0.29 11.6 5.7 0.35 11.3 4.5 1.7 1 1 0 1 1 1 0 Cell division protein ZapB HIP1_clath_bdg PF16515.5 KFX96108.1 - 0.32 11.6 7.1 0.55 10.9 7.1 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CLZ PF16526.5 KFX96108.1 - 0.45 10.9 3.7 1 9.7 2.8 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ax_dynein_light PF10211.9 KFX96108.1 - 1.4 8.8 9.3 3.6 7.5 5.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain M PF02370.16 KFX96108.1 - 3.5 8.5 6.7 3.5 8.5 0.4 2.9 2 1 0 2 2 2 0 M protein repeat H-kinase_dim PF02895.14 KFX96108.1 - 4.3 7.8 5.1 8.9 6.8 1.3 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.15 KFX96108.1 - 8.3 6.3 8.1 4.2 7.2 1.8 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF5308 PF17233.2 KFX96109.1 - 3.1e-47 160.9 1.8 3.8e-47 160.6 1.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Filament PF00038.21 KFX96110.1 - 6.7e-06 25.9 14.8 6.7e-06 25.9 14.8 4.8 3 1 3 6 6 6 2 Intermediate filament protein Tropomyosin PF00261.20 KFX96110.1 - 0.0057 16.0 22.1 0.0057 16.0 22.1 4.6 3 2 1 4 4 3 1 Tropomyosin HMMR_N PF15905.5 KFX96110.1 - 0.0065 16.0 4.4 0.0065 16.0 4.4 3.9 4 1 0 4 4 3 2 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 KFX96110.1 - 0.019 15.3 31.7 0.84 10.1 0.2 7.2 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KFX96110.1 - 0.083 13.4 9.5 8.2 7.0 0.5 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 KFX96110.1 - 0.26 11.6 0.0 0.26 11.6 0.0 7.7 7 2 0 7 7 6 0 ABC transporter C-terminal domain Bacillus_HBL PF05791.11 KFX96110.1 - 0.31 10.8 17.3 0.46 10.3 2.1 4.2 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HSBP1 PF06825.12 KFX96110.1 - 0.33 10.8 5.2 3.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 KFX96110.1 - 0.4 10.0 63.9 0.015 14.7 11.0 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KFX96110.1 - 0.58 10.8 41.0 0.24 12.0 1.2 7.4 4 1 1 7 7 7 0 SlyX TSC22 PF01166.18 KFX96110.1 - 2.2 8.6 0.0 2.2 8.6 0.0 6.3 7 0 0 7 7 7 0 TSC-22/dip/bun family BRI3BP PF14965.6 KFX96110.1 - 2.6 7.5 7.7 17 4.9 0.2 3.7 3 1 1 4 4 4 0 Negative regulator of p53/TP53 GAS PF13851.6 KFX96110.1 - 7.3 5.9 57.6 0.088 12.2 20.6 4.5 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 KFX96110.1 - 9.6 7.2 60.8 0.1 13.5 4.6 5.8 2 1 4 6 6 6 0 cGMP-dependent protein kinase interacting domain zf-C2H2 PF00096.26 KFX96111.1 - 2e-05 24.8 13.9 0.19 12.2 4.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFX96111.1 - 2.3e-05 24.6 0.1 0.00022 21.4 0.0 2.3 2 1 0 2 2 2 1 Aberrant zinc-finger APG6_N PF17675.1 KFX96111.1 - 0.00097 19.7 12.9 0.0021 18.6 12.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C2H2_4 PF13894.6 KFX96111.1 - 0.0067 17.2 9.3 9.6 7.4 3.2 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 KFX96111.1 - 0.051 14.2 1.9 0.051 14.2 1.9 4.3 2 2 2 4 4 3 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 KFX96111.1 - 0.14 11.9 0.4 0.14 11.9 0.4 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Sigma70_ner PF04546.13 KFX96111.1 - 0.2 11.5 8.6 0.3 11.0 8.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SKA2 PF16740.5 KFX96111.1 - 0.43 10.4 10.4 1 9.2 10.4 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 V_ATPase_I PF01496.19 KFX96111.1 - 0.48 8.3 9.2 0.58 8.0 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KFX96111.1 - 0.49 9.2 10.5 0.68 8.8 10.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3782 PF12644.7 KFX96111.1 - 0.6 10.3 5.2 0.84 9.8 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) DUF724 PF05266.14 KFX96111.1 - 0.82 9.5 9.2 1.3 8.8 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KFX96111.1 - 1.5 8.9 10.3 2.4 8.2 10.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KFX96111.1 - 2.5 8.4 4.6 5.6 7.2 4.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA ADIP PF11559.8 KFX96111.1 - 2.7 8.0 13.8 6 6.9 13.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 KFX96111.1 - 6.4 5.9 8.0 9.8 5.3 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Methyltransf_34 PF11312.8 KFX96112.1 - 8.7e-100 333.9 0.0 1e-99 333.7 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Syja_N PF02383.18 KFX96113.1 - 1.7e-93 313.5 0.0 2.5e-93 312.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFX96113.1 - 1e-35 121.9 0.0 1.9e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Exo_endo_phos PF03372.23 KFX96113.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3693 PF12472.8 KFX96113.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Phage related protein Response_reg PF00072.24 KFX96114.1 - 1.3e-25 89.7 0.3 2.3e-25 88.9 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KFX96114.1 - 4.4e-25 88.4 1.3 9.3e-19 68.0 0.0 3.3 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX96114.1 - 2.2e-14 53.2 0.0 5.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KFX96114.1 - 0.011 16.1 0.2 0.083 13.3 0.2 2.3 2 0 0 2 2 2 0 HAMP domain CorA PF01544.18 KFX96114.1 - 0.15 11.4 0.4 0.31 10.3 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1349 PF07081.11 KFX96116.1 - 1.1e-28 100.1 0.0 1.4e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Cyt_b-c1_8 PF10890.8 KFX96116.1 - 0.14 12.6 0.1 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Glyco_hydro_72 PF03198.14 KFX96117.1 - 3.7e-131 437.1 0.2 4.6e-131 436.8 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFX96117.1 - 0.00032 20.2 0.0 0.0024 17.3 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SH3_9 PF14604.6 KFX96118.1 - 9.2e-26 89.5 1.4 1.9e-15 56.4 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFX96118.1 - 6.7e-18 64.0 0.4 1.2e-08 34.4 0.1 2.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KFX96118.1 - 2.2e-08 33.6 0.1 0.0024 17.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KFX96118.1 - 4.6e-07 30.0 1.1 0.00018 21.7 0.4 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_10 PF17902.1 KFX96118.1 - 2.1e-05 24.5 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_16 PF18348.1 KFX96118.1 - 0.016 15.0 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain GST_N PF02798.20 KFX96128.1 - 4.2e-11 43.0 0.0 7.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX96128.1 - 3.9e-10 39.9 0.0 9.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX96128.1 - 2.9e-08 34.0 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX96128.1 - 0.00014 22.0 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX96128.1 - 0.00035 20.7 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX96128.1 - 0.0016 18.4 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_47 PF01532.20 KFX96129.1 - 1.6e-112 376.8 0.0 2.1e-112 376.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zip PF02535.22 KFX96130.1 - 1.3e-51 175.8 3.7 1.7e-51 175.4 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter ER_lumen_recept PF00810.18 KFX96131.1 - 1.2e-36 126.7 9.9 1.2e-36 126.7 9.9 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KFX96131.1 - 0.3 10.9 7.0 0.47 10.3 0.0 2.9 3 0 0 3 3 3 0 PQ loop repeat 7TMR-DISM_7TM PF07695.11 KFX96131.1 - 0.52 10.2 13.5 0.14 12.0 10.7 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling CN_hydrolase PF00795.22 KFX96134.1 - 6.9e-17 61.6 0.0 4.2e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 KFX96142.1 - 8.3e-16 57.8 0.0 2.6e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_6 PF08030.12 KFX96144.1 - 1.8e-20 73.7 0.0 1.2e-12 48.2 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX96144.1 - 4.1e-13 49.4 0.0 5e-12 45.9 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain Ctr PF04145.15 KFX96145.1 - 1.6e-23 84.0 0.0 1.8e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Papilloma_E5A PF05776.12 KFX96145.1 - 0.058 13.8 1.6 0.73 10.2 0.1 2.1 2 0 0 2 2 2 0 Papillomavirus E5A protein Abhydrolase_3 PF07859.13 KFX96146.1 - 3.5e-07 30.3 0.0 4.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold TUG-UBL1 PF11470.8 KFX96179.1 - 5e-18 65.1 0.0 1.8e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 KFX96179.1 - 2.1e-07 31.0 0.3 0.045 13.9 0.0 3.3 3 1 0 3 3 3 2 UBX domain FERM_N PF09379.10 KFX96179.1 - 0.034 14.1 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 FERM N-terminal domain Ribosomal_L36e PF01158.18 KFX96180.1 - 2e-39 133.7 5.7 2.8e-39 133.3 5.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e DAGAT PF03982.13 KFX96180.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase IF-2B PF01008.17 KFX96181.1 - 1e-72 244.7 0.0 1.7e-72 244.0 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family eIF-3c_N PF05470.12 KFX96181.1 - 0.033 12.5 0.1 0.047 12.0 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA PF00004.29 KFX96182.1 - 2.2e-10 41.1 0.0 5.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX96182.1 - 9.6e-09 35.6 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX96182.1 - 4.8e-08 33.6 0.0 2e-07 31.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 KFX96182.1 - 1.7e-07 31.1 0.3 1.5e-06 28.0 0.3 2.3 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KFX96182.1 - 1.8e-05 24.8 0.0 6.2e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KFX96182.1 - 2.8e-05 24.5 0.1 0.00022 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX96182.1 - 0.0036 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ssDBP PF17878.1 KFX96182.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Single-stranded DNA-binding protein AAA_11 PF13086.6 KFX96182.1 - 0.0071 16.2 0.2 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX96182.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX96182.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 KFX96182.1 - 0.023 14.1 0.1 0.22 10.9 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 KFX96182.1 - 0.16 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KFX96182.1 - 0.2 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KFX96182.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WW PF00397.26 KFX96183.1 - 7.2e-11 42.0 0.1 1.6e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KFX96183.1 - 0.0047 16.0 0.0 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase PMM PF03332.13 KFX96184.1 - 5.6e-104 346.7 0.2 6.3e-104 346.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase adh_short PF00106.25 KFX96191.1 - 1.2e-26 93.4 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96191.1 - 1.4e-17 64.1 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96191.1 - 1e-06 28.8 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX96191.1 - 2e-05 24.6 0.0 5.3e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 KFX96191.1 - 0.00014 22.1 0.6 0.004 17.4 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.13 KFX96191.1 - 0.00026 20.7 0.1 0.00041 20.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KFX96191.1 - 0.0023 17.1 0.1 0.52 9.4 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX96191.1 - 0.02 14.3 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 KFX96192.1 - 3.3e-36 124.9 2.0 5e-36 124.3 2.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96192.1 - 6.1e-07 29.5 8.5 1e-06 28.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_protease_2 PF13650.6 KFX96193.1 - 0.031 14.9 0.0 0.09 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease dCache_2 PF08269.11 KFX96193.1 - 0.037 13.2 1.6 0.1 11.7 0.1 2.0 1 1 0 2 2 2 0 Cache domain Helo_like_N PF17111.5 KFX96193.1 - 0.26 10.6 2.4 0.17 11.3 0.3 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF3159 PF11361.8 KFX96194.1 - 0.28 10.9 4.7 0.41 10.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Peptidase_S28 PF05577.12 KFX96204.1 - 4.2e-48 164.2 0.0 2.5e-47 161.7 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KFX96204.1 - 9.2e-05 21.3 0.3 0.26 9.9 0.1 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 TPR_12 PF13424.6 KFX96208.1 - 2.5e-49 165.5 18.9 1.1e-10 41.6 0.7 8.9 4 2 4 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 KFX96208.1 - 2.3e-45 151.3 7.6 2.4e-07 30.4 0.0 10.7 11 0 0 11 11 10 8 Tetratricopeptide repeat SesA PF17107.5 KFX96208.1 - 2.4e-23 82.7 0.2 6.9e-23 81.2 0.2 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_MalT PF17874.1 KFX96208.1 - 1.6e-09 37.7 4.0 1.2e-05 24.8 0.2 4.1 3 1 1 4 4 4 2 MalT-like TPR region NB-ARC PF00931.22 KFX96208.1 - 9.4e-08 31.5 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 KFX96208.1 - 0.00016 21.6 9.7 3.7 7.9 0.2 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFX96208.1 - 0.00023 20.9 12.0 0.94 9.7 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFX96208.1 - 0.00041 20.8 0.0 0.0013 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 KFX96208.1 - 0.0016 18.7 0.1 17 6.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KFX96208.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_4 PF07721.14 KFX96208.1 - 0.0061 17.1 0.4 6.5 7.7 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 KFX96208.1 - 0.024 14.9 0.0 0.081 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain TPR_19 PF14559.6 KFX96208.1 - 0.27 11.8 1.9 4.1 8.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96208.1 - 0.37 11.7 7.9 17 6.5 0.1 5.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX96208.1 - 0.84 9.6 15.6 24 5.0 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX96208.1 - 3.2 8.5 13.5 31 5.3 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.18 KFX96209.1 - 1.1e-36 126.1 0.0 4.2e-36 124.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFX96209.1 - 9.6e-17 61.2 0.0 2.9e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX96209.1 - 2e-06 27.6 0.0 1.1e-05 25.2 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Gly_transf_sug PF04488.15 KFX96210.1 - 3.5e-07 30.7 0.0 8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF899 PF05988.12 KFX96215.1 - 3.5e-79 265.3 0.0 4.2e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 KFX96215.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Ysc84 PF04366.12 KFX96216.1 - 3.3e-42 143.2 0.4 5.8e-42 142.5 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KFX96216.1 - 2.6e-14 52.6 0.2 9.5e-14 50.7 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFX96216.1 - 3.9e-14 52.0 0.1 1.8e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFX96216.1 - 1.1e-12 47.6 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.21 KFX96217.1 - 0.075 12.8 0.2 4 7.3 0.0 2.0 1 1 1 2 2 2 0 Synaptobrevin Zn_clus PF00172.18 KFX96221.1 - 4.6e-07 29.8 9.7 7.9e-07 29.1 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX96221.1 - 2.3e-06 26.7 0.3 3.1e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain INTAP PF16617.5 KFX96226.1 - 0.061 13.7 0.1 0.084 13.2 0.1 1.3 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Abhydrolase_4 PF08386.10 KFX96226.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 KFX96226.1 - 0.2 11.3 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PigN PF04987.14 KFX96228.1 - 9.1e-163 542.3 27.1 9.1e-163 542.3 27.1 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.8 KFX96228.1 - 5.9e-33 113.3 0.1 1.4e-32 112.2 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.22 KFX96228.1 - 3.1e-09 36.9 10.0 4.4e-09 36.4 3.4 3.0 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX96228.1 - 1.9e-07 30.8 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Lebercilin PF15619.6 KFX96228.1 - 0.00055 19.7 30.1 0.00055 19.7 30.1 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Metalloenzyme PF01676.18 KFX96228.1 - 0.00083 18.8 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF5094 PF17015.5 KFX96228.1 - 0.43 10.7 0.0 0.43 10.7 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5094) Atg14 PF10186.9 KFX96228.1 - 3.8 6.5 25.0 7 5.6 25.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 KFX96228.1 - 7.5 7.1 11.4 5.1 7.6 2.4 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein QCR10 PF09796.9 KFX96232.1 - 3.8e-28 97.3 1.0 4.9e-28 97.0 1.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) U-box PF04564.15 KFX96233.1 - 2e-20 72.7 0.0 3.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KFX96233.1 - 8.1e-07 28.6 4.7 0.0043 16.8 0.2 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX96233.1 - 1.7e-05 24.4 1.1 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 KFX96233.1 - 4e-05 23.4 6.0 0.0066 16.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX96233.1 - 0.00082 20.0 0.1 0.00082 20.0 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX96233.1 - 0.0026 17.8 3.0 2.2 8.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX96233.1 - 0.0048 17.2 0.2 0.037 14.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX96233.1 - 0.022 14.9 0.0 0.022 14.9 0.0 2.5 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-Nse PF11789.8 KFX96233.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KFX96233.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_12 PF13424.6 KFX96233.1 - 0.32 11.3 8.1 4.2 7.7 0.8 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96233.1 - 0.55 11.2 7.3 1.3 10.1 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4192 PF13830.6 KFX96233.1 - 1 9.3 7.9 1 9.4 5.9 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4192) Med8 PF10232.9 KFX96233.1 - 1.3 8.5 4.5 1.9 8.1 3.9 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 TPR_19 PF14559.6 KFX96233.1 - 1.4 9.5 6.8 3.3 8.3 0.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KFX96235.1 - 3.6e-23 82.0 0.0 6.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX96235.1 - 9.5e-14 52.6 0.0 2.2e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX96235.1 - 2.8e-07 30.4 0.0 8.2e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFX96235.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Glyco_hydro_7 PF00840.20 KFX96236.1 - 3.7e-148 493.8 1.0 4.7e-148 493.5 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Notch PF00066.17 KFX96236.1 - 0.7 10.4 0.1 0.7 10.4 0.1 4.4 5 1 0 5 5 5 0 LNR domain Peptidase_S58 PF03576.14 KFX96237.1 - 6.6e-91 304.9 2.5 8.2e-91 304.6 2.5 1.0 1 0 0 1 1 1 1 Peptidase family S58 Transferase PF02458.15 KFX96238.1 - 1.9e-38 132.3 0.0 1.1e-20 73.7 0.0 2.8 2 1 0 2 2 2 2 Transferase family Flavin_Reduct PF01613.18 KFX96239.1 - 1.3e-09 38.2 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KFX96239.1 - 0.00068 19.5 0.3 0.0024 17.7 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 KFX96239.1 - 0.037 14.2 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ADH_zinc_N PF00107.26 KFX96240.1 - 4.5e-09 36.4 0.0 8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX96240.1 - 7.5e-09 35.5 0.0 1.8e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KFX96240.1 - 0.012 15.0 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 KFX96240.1 - 0.026 15.6 0.0 0.054 14.5 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX96240.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Zn_clus PF00172.18 KFX96241.1 - 1.5e-06 28.2 9.8 1.5e-06 28.2 9.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ig_GlcNase PF18368.1 KFX96242.1 - 2.8e-34 117.4 7.7 3.4e-34 117.1 0.2 3.1 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KFX96242.1 - 9.2e-12 45.6 2.9 5e-11 43.3 0.1 3.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KFX96242.1 - 1.4e-07 32.0 0.6 1.4e-07 32.0 0.6 3.0 2 1 1 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 KFX96242.1 - 1.2e-05 25.3 0.2 4.4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KFX96242.1 - 8.6e-05 22.2 0.1 8.6e-05 22.2 0.1 2.9 4 0 0 4 4 4 1 Ig-fold domain DUF4232 PF14016.6 KFX96242.1 - 0.012 15.8 3.6 0.014 15.6 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Glyco_hydro_2_C PF02836.17 KFX96242.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AA_permease_2 PF13520.6 KFX96243.1 - 4.9e-50 170.6 57.4 6e-50 170.3 57.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX96243.1 - 3.1e-21 75.5 48.5 4.1e-21 75.1 48.5 1.0 1 0 0 1 1 1 1 Amino acid permease Gly_transf_sug PF04488.15 KFX96244.1 - 6.4e-11 42.8 0.1 1.3e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif L_HMGIC_fpl PF10242.9 KFX96244.1 - 0.0031 17.7 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Hexokinase_1 PF00349.21 KFX96245.1 - 6.6e-63 212.2 0.0 9e-63 211.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KFX96245.1 - 1.3e-62 211.4 0.0 1.2e-48 165.6 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Zn_clus PF00172.18 KFX96246.1 - 7.3e-06 26.0 8.5 1.3e-05 25.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHBC_N PF12551.8 KFX96246.1 - 0.092 12.5 2.5 0.16 11.8 0.3 2.4 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal CAAD PF14159.6 KFX96246.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Cutinase PF01083.22 KFX96247.1 - 6.9e-51 172.7 1.5 8e-51 172.5 1.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFX96247.1 - 0.00078 19.1 0.2 0.0012 18.5 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KFX96247.1 - 0.0029 17.2 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KFX96247.1 - 0.0037 17.0 0.1 0.0044 16.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KFX96247.1 - 0.0038 17.4 0.1 0.005 17.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain VirJ PF06057.11 KFX96247.1 - 0.011 15.6 0.0 0.1 12.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 KFX96247.1 - 0.035 14.0 0.1 0.047 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 KFX96247.1 - 0.05 13.4 0.0 0.052 13.4 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 KFX96247.1 - 0.096 12.5 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KFX96247.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) F-box-like PF12937.7 KFX96248.1 - 7.7e-05 22.5 0.1 0.00039 20.2 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX96248.1 - 0.0077 16.1 2.7 0.014 15.3 0.6 2.6 3 0 0 3 3 3 1 F-box domain Uteroglobin PF01099.17 KFX96248.1 - 0.13 12.6 0.1 2.1 8.7 0.1 2.7 2 0 0 2 2 2 0 Uteroglobin family HSCB_C PF07743.13 KFX96248.1 - 0.29 11.7 2.6 1 9.9 0.0 3.3 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain MFS_1 PF07690.16 KFX96249.1 - 4.3e-34 118.0 34.4 6.5e-34 117.4 34.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 KFX96250.1 - 2.6e-72 244.3 0.1 3.5e-72 243.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX96250.1 - 3.3e-08 33.6 0.5 4.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX96250.1 - 0.0021 17.0 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Fungal_trans PF04082.18 KFX96251.1 - 0.00013 21.1 0.2 0.00023 20.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 KFX96252.1 - 1.8e-36 125.9 1.0 2.2e-36 125.6 1.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX96252.1 - 2.2e-20 73.3 0.1 2.9e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFX96252.1 - 5.8e-05 23.4 0.4 0.00014 22.2 0.4 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFX96252.1 - 0.00043 19.8 0.5 0.0084 15.6 0.4 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX96252.1 - 0.003 16.6 2.1 0.0073 15.3 0.9 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KFX96252.1 - 0.032 14.4 0.2 0.062 13.4 0.2 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KFX96252.1 - 0.038 14.6 0.9 0.24 12.0 0.9 2.1 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIR-like PF10137.9 KFX96252.1 - 0.12 12.3 0.1 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain Zn_clus PF00172.18 KFX96254.1 - 0.012 15.7 13.1 0.012 15.7 13.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4083 PF13314.6 KFX96254.1 - 0.094 12.7 1.6 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) AP_endonuc_2 PF01261.24 KFX96255.1 - 1.1e-27 96.8 0.0 1.5e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3544 PF12064.8 KFX96255.1 - 0.27 11.5 0.0 0.39 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 ADP_ribosyl_GH PF03747.14 KFX96256.1 - 3.3e-58 197.7 0.0 4e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KFX96256.1 - 0.0022 17.8 7.8 0.26 11.2 0.6 2.4 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KFX96256.1 - 0.0057 16.6 5.3 0.4 10.7 1.0 2.5 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.6 KFX96256.1 - 0.017 14.9 6.1 0.22 11.3 0.9 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Transgly_assoc PF04226.13 KFX96256.1 - 0.062 13.6 0.3 5.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein Gly-zipper_OmpA PF13436.6 KFX96256.1 - 0.27 11.1 5.3 1.1 9.1 0.6 2.6 2 0 0 2 2 2 0 Glycine-zipper domain Glyco_hydro_43 PF04616.14 KFX96257.1 - 4.4e-27 95.1 7.0 4.4e-27 95.1 7.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX96257.1 - 4.9e-22 78.6 0.4 7.8e-22 78.0 0.4 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Ribosomal_L7Ae PF01248.26 KFX96258.1 - 1.9e-22 78.8 0.0 2.1e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynamin_N PF00350.23 KFX96259.1 - 8.3e-31 107.3 1.3 1.5e-30 106.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KFX96259.1 - 6.1e-28 97.9 0.2 6.3e-26 91.3 0.4 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KFX96259.1 - 0.0012 18.9 0.1 0.0035 17.5 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFX96259.1 - 0.0026 17.8 0.2 0.052 13.6 0.2 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX96259.1 - 0.04 14.3 0.1 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KFX96259.1 - 0.1 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NOA36 PF06524.12 KFX96259.1 - 0.34 10.2 9.4 0.56 9.5 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein APH PF01636.23 KFX96260.1 - 2.1e-05 24.6 0.2 5.7e-05 23.1 0.2 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFX96260.1 - 0.00018 20.5 0.0 0.0018 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) DFF-C PF09033.10 KFX96260.1 - 0.19 11.6 1.0 7.7 6.4 0.1 2.3 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Fungal_trans PF04082.18 KFX96262.1 - 8.6e-37 126.6 0.0 1.7e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96262.1 - 1e-07 31.9 8.4 1.7e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAV_VP3 PF04771.12 KFX96262.1 - 0.22 11.7 6.4 0.51 10.5 6.4 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Kinetochor_Ybp2 PF08568.10 KFX96263.1 - 1e-120 404.2 0.0 1.3e-120 403.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin ILVD_EDD PF00920.21 KFX96264.1 - 2.3e-209 696.3 2.5 2.6e-209 696.1 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Bgal_small_N PF02929.17 KFX96265.1 - 4.7e-41 141.0 0.0 6e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Beta galactosidase small chain ADH_zinc_N PF00107.26 KFX96270.1 - 1.8e-15 57.1 0.2 3.2e-15 56.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX96270.1 - 2.2e-05 25.5 0.0 3.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MORN PF02493.20 KFX96270.1 - 5.3 7.1 6.1 8.9 6.4 0.2 3.0 3 0 0 3 3 3 0 MORN repeat CBFD_NFYB_HMF PF00808.23 KFX96271.1 - 2.8e-17 62.7 0.6 5.4e-17 61.8 0.3 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX96271.1 - 2.2e-06 28.0 0.1 1.1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5333 PF17267.2 KFX96271.1 - 0.012 15.8 0.5 0.016 15.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Bromo_TP PF07524.13 KFX96271.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated adh_short PF00106.25 KFX96273.1 - 2.2e-42 144.8 0.3 2.6e-42 144.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96273.1 - 9.4e-32 110.4 0.2 1.1e-31 110.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96273.1 - 1.1e-08 35.2 0.3 1.6e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX96273.1 - 0.00015 21.7 1.1 0.00032 20.7 1.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX96273.1 - 0.0013 17.9 0.3 0.0027 16.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX96273.1 - 0.0064 16.0 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFX96273.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 KFX96273.1 - 0.015 15.6 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain PP2C_2 PF13672.6 KFX96273.1 - 0.024 14.3 0.2 0.035 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C dCMP_cyt_deam_1 PF00383.23 KFX96275.1 - 2.6e-23 81.8 0.0 3.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFX96275.1 - 5.5e-16 58.6 0.1 1.2e-06 28.4 0.0 2.3 2 1 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KFX96275.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase NADH-u_ox-rdase PF10785.9 KFX96276.1 - 9.1e-30 103.2 0.2 1.4e-29 102.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KFX96276.1 - 3.5e-28 97.4 0.1 5.1e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Nup54 PF13874.6 KFX96277.1 - 5.7e-39 133.4 0.0 5.7e-39 133.4 0.0 2.8 3 1 0 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KFX96277.1 - 1.1e-13 51.8 84.3 5.4e-08 33.6 36.7 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nup54_57_C PF18570.1 KFX96277.1 - 2.6e-10 39.7 0.1 5.8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain PMSI1 PF15322.6 KFX96277.1 - 0.056 12.9 11.4 0.12 11.8 11.4 1.5 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ub-RnfH PF03658.14 KFX96277.1 - 0.35 11.3 4.6 8.6 6.8 0.3 2.8 1 1 1 2 2 2 0 RnfH family Ubiquitin Med26 PF08711.11 KFX96278.1 - 2.5e-09 37.0 0.0 5.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Phosphodiest PF01663.22 KFX96279.1 - 9.9e-94 314.8 0.1 1.3e-93 314.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX96279.1 - 0.0024 17.3 0.2 0.11 11.9 0.2 2.5 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFX96279.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 PglZ domain DUF2063 PF09836.9 KFX96279.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain PAM2 PF07145.15 KFX96280.1 - 0.82 9.5 20.9 1 9.2 0.0 5.1 5 1 1 6 6 6 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.18 KFX96281.1 - 8.5e-37 127.4 1.6 1.3e-35 123.5 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PQ-loop PF04193.14 KFX96282.1 - 1.8e-37 126.9 13.7 7.9e-21 73.6 0.0 3.3 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFX96282.1 - 0.19 12.6 2.3 1.7 9.5 0.2 2.5 2 1 0 2 2 2 0 ER lumen protein retaining receptor GRIP PF01465.20 KFX96298.1 - 3.9e-06 26.7 0.0 4.2e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 GRIP domain HEAT_EZ PF13513.6 KFX96298.1 - 0.015 15.8 0.0 0.016 15.7 0.0 1.0 1 0 0 1 1 1 0 HEAT-like repeat MFS_2 PF13347.6 KFX96301.1 - 6.5e-12 44.7 17.0 1.2e-10 40.6 13.9 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFX96301.1 - 0.00092 18.2 0.4 0.00092 18.2 0.4 1.9 2 2 0 2 2 2 1 MFS_1 like family ABC2_membrane_5 PF13346.6 KFX96301.1 - 9.1 5.8 13.3 19 4.7 7.2 3.5 2 1 1 3 3 3 0 ABC-2 family transporter protein Gly-zipper_Omp PF13488.6 KFX96304.1 - 1.7 8.7 4.9 0.84 9.7 0.4 2.5 3 0 0 3 3 3 0 Glycine zipper NDUF_B12 PF08122.12 KFX96304.1 - 1.8 8.7 9.2 48 4.1 0.3 4.0 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family ERAP1_C PF11838.8 KFX96305.1 - 3.4e-86 289.7 0.1 1.8e-85 287.3 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFX96305.1 - 4.4e-85 284.7 0.4 8.5e-85 283.7 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFX96305.1 - 4.9e-50 170.3 2.5 8.4e-50 169.5 2.5 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3224 PF11528.8 KFX96305.1 - 0.056 13.2 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) DUF2808 PF10989.8 KFX96305.1 - 0.077 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) WD40 PF00400.32 KFX96306.1 - 0.0044 17.8 2.2 0.09 13.7 0.7 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat BicD PF09730.9 KFX96306.1 - 0.034 12.6 14.4 0.048 12.1 14.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D SKA1 PF07160.12 KFX96306.1 - 0.13 12.1 12.2 0.22 11.4 12.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Eaf7 PF07904.13 KFX96306.1 - 0.28 11.6 3.9 0.98 9.8 3.9 2.0 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 MCPVI PF02993.14 KFX96306.1 - 0.33 10.7 4.4 0.62 9.8 4.4 1.4 1 0 0 1 1 1 0 Minor capsid protein VI DUF4477 PF14780.6 KFX96306.1 - 0.41 10.2 1.6 0.84 9.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Alpha-E PF04168.12 KFX96306.1 - 0.61 9.8 4.3 1.1 9.0 4.3 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. FUSC PF04632.12 KFX96306.1 - 0.61 8.5 5.7 0.95 7.9 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 KFX96306.1 - 0.73 7.7 7.4 1 7.2 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KFX96306.1 - 2.7 6.7 4.0 3.7 6.2 4.0 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 KFX96306.1 - 4 7.5 9.1 6.4 6.8 9.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Baculo_p24 PF05073.12 KFX96306.1 - 4.4 7.1 8.6 8.6 6.1 8.6 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Roughex PF06020.11 KFX96306.1 - 4.7 6.2 10.3 8.3 5.4 10.3 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Fip1 PF05182.13 KFX96308.1 - 2.8e-20 71.6 0.9 5.8e-20 70.5 0.9 1.6 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 KFX96309.1 - 4.4e-17 62.7 80.7 3.7e-09 37.3 23.9 3.6 1 1 2 3 3 3 2 Nucleoporin FG repeat region SUIM_assoc PF16619.5 KFX96309.1 - 5.1 7.2 11.4 87 3.3 9.8 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 KFX96310.1 - 0.0002 22.1 12.1 0.32 11.9 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96310.1 - 0.0035 17.6 0.0 0.56 10.6 0.0 3.6 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NOA36 PF06524.12 KFX96310.1 - 0.68 9.2 1.9 1.1 8.6 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein PQ-loop PF04193.14 KFX96311.1 - 3.4e-21 74.8 18.5 2.4e-11 43.2 1.8 3.4 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFX96311.1 - 0.013 16.3 1.3 0.049 14.5 0.4 2.1 1 1 1 2 2 2 0 ER lumen protein retaining receptor Adipogenin PF15202.6 KFX96311.1 - 0.23 11.5 4.7 6.6 6.8 0.6 2.6 2 0 0 2 2 2 0 Adipogenin DUF2975 PF11188.8 KFX96311.1 - 5.9 6.8 9.5 0.39 10.6 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) GST_N PF02798.20 KFX96313.1 - 3.8e-15 56.0 0.1 6.8e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX96313.1 - 2.6e-14 53.4 0.0 4.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX96313.1 - 1.2e-11 44.7 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX96313.1 - 1.8e-11 44.2 0.0 3.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX96313.1 - 3.9e-11 43.0 0.1 6.1e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX96313.1 - 6.8e-05 22.8 0.1 0.00011 22.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 KFX96313.1 - 0.015 14.4 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) GST_N_4 PF17172.4 KFX96313.1 - 0.021 15.6 0.0 0.077 13.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KFX96313.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GMC_oxred_N PF00732.19 KFX96314.1 - 2.4e-56 191.3 0.0 3.3e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX96314.1 - 1.2e-34 119.9 0.1 2.6e-34 118.8 0.0 1.6 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX96314.1 - 2.1e-09 37.0 0.7 1.4e-07 31.0 0.7 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX96314.1 - 1.6e-05 24.7 0.0 0.00029 20.5 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFX96314.1 - 4.9e-05 22.7 0.3 0.18 11.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX96314.1 - 0.00044 19.4 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX96314.1 - 0.0005 19.4 0.0 0.0028 16.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX96314.1 - 0.00094 19.4 0.2 0.0036 17.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX96314.1 - 0.009 15.3 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KFX96314.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KFX96314.1 - 0.16 12.2 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain FTA2 PF13095.6 KFX96315.1 - 4.2e-07 29.8 0.1 0.00017 21.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Peptidase_M3 PF01432.20 KFX96316.1 - 2.5e-121 406.2 0.0 9e-121 404.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 adh_short PF00106.25 KFX96316.1 - 2e-40 138.3 0.0 3.2e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96316.1 - 1.7e-29 103.1 0.0 3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96316.1 - 2.1e-06 27.8 0.0 5.3e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 KFX96316.1 - 0.0017 17.8 0.0 1.2 8.4 0.0 2.6 3 0 0 3 3 3 2 Fungal family of unknown function (DUF1776) Cupin_6 PF12852.7 KFX96316.1 - 0.009 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Cupin NmrA PF05368.13 KFX96316.1 - 0.017 14.7 0.2 0.029 13.9 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KFX96316.1 - 0.02 14.4 0.2 0.049 13.1 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 KFX96316.1 - 0.046 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda 2-Hacid_dh_C PF02826.19 KFX96316.1 - 0.11 11.9 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFX96316.1 - 0.14 12.4 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KFX96316.1 - 0.29 11.0 0.9 0.46 10.4 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KFX96317.1 - 0.00011 22.2 7.2 0.00019 21.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX96317.1 - 0.00036 19.7 2.1 0.0016 17.5 0.4 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KFX96318.1 - 2.1e-107 359.8 17.3 2.5e-107 359.5 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96318.1 - 1.6e-23 83.3 34.5 5.4e-22 78.2 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX96318.1 - 0.0023 16.5 0.5 0.0058 15.1 0.5 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.16 KFX96319.1 - 1.2e-55 189.2 0.1 1.4e-55 188.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_N PF08240.12 KFX96320.1 - 1.5e-26 92.4 6.9 3.4e-26 91.2 6.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX96320.1 - 4.2e-19 68.8 1.6 6.5e-19 68.2 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX96320.1 - 6.4e-06 27.3 0.1 1.1e-05 26.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX96320.1 - 0.12 11.9 0.4 0.17 11.3 0.4 1.3 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Aldedh PF00171.22 KFX96321.1 - 3e-134 448.0 0.1 3.6e-134 447.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFX96321.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3201 PF11447.8 KFX96321.1 - 0.094 12.2 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) Aa_trans PF01490.18 KFX96322.1 - 4.4e-81 272.7 24.8 5.2e-81 272.5 24.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fig1 PF12351.8 KFX96322.1 - 0.028 14.4 5.2 0.65 9.9 1.1 2.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 OST3_OST6 PF04756.13 KFX96322.1 - 3.4 6.9 6.4 0.77 9.1 0.5 2.4 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family MFS_1 PF07690.16 KFX96323.1 - 3.3e-13 49.3 16.2 3.3e-13 49.3 16.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DDE_Tnp_IS1 PF03400.13 KFX96324.1 - 0.038 14.3 0.1 0.075 13.4 0.1 1.4 1 0 0 1 1 1 0 IS1 transposase Sugar_tr PF00083.24 KFX96325.1 - 2.7e-67 227.6 20.9 3.4e-67 227.3 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96325.1 - 3.1e-16 59.3 28.4 5.5e-13 48.6 24.4 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_127 PF07944.12 KFX96326.1 - 8.1e-117 390.8 0.0 9.8e-117 390.6 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF3455 PF11937.8 KFX96327.1 - 3.1e-44 151.2 0.1 3.9e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KFX96327.1 - 0.024 14.8 3.7 0.042 14.0 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2990) Cation_efflux PF01545.21 KFX96329.1 - 1.3e-17 64.2 9.9 1.6e-17 63.9 9.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFX96329.1 - 3.3e-09 36.7 0.3 7.4e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter zf-rbx1 PF12678.7 KFX96330.1 - 5.4e-08 33.0 6.3 5.4e-07 29.8 6.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX96330.1 - 6.7e-08 32.7 2.0 6.7e-08 32.7 2.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFX96330.1 - 8.3e-06 25.6 0.6 2.9e-05 23.9 0.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX96330.1 - 1.8e-05 24.5 5.0 0.00012 21.8 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX96330.1 - 2.3e-05 24.3 1.1 0.00011 22.2 1.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFX96330.1 - 3.5e-05 23.6 1.8 0.00022 21.1 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX96330.1 - 0.0004 20.2 2.8 0.0004 20.2 2.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX96330.1 - 0.001 18.7 0.9 0.0022 17.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFX96330.1 - 0.0011 18.8 1.0 0.0011 18.8 1.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFX96330.1 - 0.012 15.6 1.7 0.062 13.3 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFX96330.1 - 0.067 13.4 1.0 0.15 12.2 1.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KFX96330.1 - 0.21 11.3 1.3 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KFX96330.1 - 0.59 10.0 3.7 0.22 11.4 0.8 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.20 KFX96331.1 - 2e-20 73.5 1.8 1.3e-19 70.8 1.8 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFX96331.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative VCBS PF13517.6 KFX96332.1 - 3.2e-34 117.3 52.7 1.9e-09 38.0 2.7 8.8 4 2 5 9 9 9 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX96332.1 - 1.6e-07 31.9 0.2 4.1e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KFX96332.1 - 1.1e-06 28.6 29.7 0.0077 16.3 1.1 6.5 6 0 0 6 6 6 4 FG-GAP repeat Lipase_GDSL PF00657.22 KFX96332.1 - 2.1e-06 27.9 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KFX96332.1 - 4.2e-06 26.3 7.5 2.4 7.5 0.0 6.4 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region HMG_box PF00505.19 KFX96361.1 - 9.2e-11 42.0 0.1 9.2e-11 42.0 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX96361.1 - 8.2e-05 23.1 0.2 0.00025 21.6 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain Sld5 PF05916.11 KFX96362.1 - 1.2e-11 45.0 0.1 1.9e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.8 KFX96362.1 - 0.044 13.5 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) TerB PF05099.13 KFX96362.1 - 0.18 11.7 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Sulfate_transp PF00916.20 KFX96363.1 - 5.4e-67 226.2 13.5 7.8e-67 225.7 13.5 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KFX96363.1 - 4.6e-16 58.7 0.0 8.9e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KFX96363.1 - 2.8e-09 36.6 0.0 5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFX96363.1 - 0.21 12.0 14.5 3.9 7.9 3.8 3.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Rer1 PF03248.13 KFX96363.1 - 0.96 9.2 7.4 2 8.1 7.4 1.5 1 0 0 1 1 1 0 Rer1 family DUF2613 PF11021.8 KFX96363.1 - 1.2 9.2 5.3 0.42 10.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF3180 PF11377.8 KFX96363.1 - 3.8 7.7 9.6 0.84 9.8 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Glyco_hydro_10 PF00331.20 KFX96364.1 - 6.8e-94 314.6 5.4 8.6e-94 314.2 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.25 KFX96365.1 - 8.7e-33 113.4 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96365.1 - 4.5e-27 95.1 0.0 5.3e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96365.1 - 4.5e-10 39.7 0.1 1.2e-09 38.3 0.1 1.8 1 1 0 1 1 1 1 KR domain Ras PF00071.22 KFX96366.1 - 2.4e-40 137.8 0.0 3.6e-40 137.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFX96366.1 - 4.7e-29 101.0 0.0 6.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX96366.1 - 2.7e-10 40.0 0.0 3.9e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX96366.1 - 0.00046 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX96366.1 - 0.0012 18.2 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFX96366.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFX96366.1 - 0.019 15.5 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KFX96366.1 - 0.022 14.3 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFX96366.1 - 0.03 14.7 0.9 0.2 12.0 0.9 2.2 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFX96366.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KFX96366.1 - 0.042 13.6 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX96366.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KFX96366.1 - 0.099 12.4 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFX96366.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFX96366.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFX96366.1 - 0.29 10.6 0.0 0.48 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Sugar_tr PF00083.24 KFX96367.1 - 1.2e-103 347.5 15.3 1.4e-103 347.2 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96367.1 - 3e-23 82.3 24.1 1.4e-21 76.8 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX96367.1 - 4.9e-05 21.9 9.2 0.0072 14.8 1.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFX96367.1 - 0.00052 18.7 17.4 0.0044 15.6 1.2 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Sulfatase PF00884.23 KFX96368.1 - 7.4e-73 245.6 0.0 8.9e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFX96368.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFX96368.1 - 0.19 11.3 0.2 1.2 8.7 0.0 2.1 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.18 KFX96369.1 - 3.5e-07 30.2 6.1 7.1e-07 29.3 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX96369.1 - 0.00052 19.1 0.2 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HSF_DNA-bind PF00447.17 KFX96369.1 - 0.11 13.1 0.3 20 5.8 0.0 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding RPN5_C PF18098.1 KFX96369.1 - 0.91 9.7 3.7 0.71 10.0 0.2 2.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Peptidase_A4 PF01828.17 KFX96370.1 - 4.2e-54 183.2 12.2 6.6e-54 182.6 12.2 1.2 1 0 0 1 1 1 1 Peptidase A4 family Ecm33 PF12454.8 KFX96370.1 - 0.0018 18.3 0.7 0.46 10.7 0.0 2.5 2 0 0 2 2 2 2 GPI-anchored cell wall organization protein Poly_export PF02563.16 KFX96370.1 - 0.0047 17.1 0.2 0.49 10.6 0.2 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein Dynamin_N PF00350.23 KFX96372.1 - 1.3e-29 103.5 0.0 3.5e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX96372.1 - 3.5e-23 82.3 0.1 5.6e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KFX96372.1 - 8.9e-05 22.6 0.0 0.0011 19.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KFX96372.1 - 0.00085 19.4 0.0 0.0028 17.8 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain CotJA PF11007.8 KFX96372.1 - 0.099 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) EHN PF06441.12 KFX96373.1 - 1.6e-17 63.9 0.2 2.6e-15 56.7 0.1 2.3 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFX96373.1 - 6.5e-17 62.0 0.0 9.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX96373.1 - 1.5e-05 25.7 0.1 2.4e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.7 KFX96374.1 - 0.00036 20.4 1.3 0.00078 19.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like RskA PF10099.9 KFX96382.1 - 1.1 9.5 13.6 1.4 9.2 13.6 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BCAS3 PF12490.8 KFX96382.1 - 1.6 8.2 3.6 1.4 8.4 3.6 1.0 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DUF1793 PF08760.11 KFX96384.1 - 2.6e-71 239.4 0.1 4.9e-71 238.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KFX96384.1 - 2.2e-63 213.0 0.8 1.1e-47 162.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KFX96384.1 - 3e-42 144.9 0.1 7.1e-42 143.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KFX96384.1 - 0.0039 16.7 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Cellulase PF00150.18 KFX96386.1 - 3e-08 33.4 0.1 3e-08 33.4 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SR-25 PF10500.9 KFX96386.1 - 0.17 11.5 36.1 0.32 10.6 36.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LAP1C PF05609.12 KFX96386.1 - 0.54 9.3 9.1 0.78 8.8 9.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) OAD_gamma PF04277.13 KFX96386.1 - 4.4 8.0 4.8 6.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Transket_pyr PF02779.24 KFX96387.1 - 1.7e-42 145.1 0.0 2.7e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFX96387.1 - 6.8e-32 110.0 0.0 1.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KFX96387.1 - 0.00081 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Oxidored_FMN PF00724.20 KFX96388.1 - 1.1e-50 172.8 0.0 1.4e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 KFX96388.1 - 0.0016 17.5 1.5 0.12 11.3 0.5 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Dus PF01207.17 KFX96388.1 - 0.048 12.7 0.2 0.96 8.5 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1611_N PF17396.2 KFX96388.1 - 0.09 13.0 0.1 30 4.9 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain GRAM PF02893.20 KFX96396.1 - 1.9e-22 79.3 0.1 3.7e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Peptidase_S8 PF00082.22 KFX96413.1 - 1.4e-36 126.3 3.5 1.9e-36 125.9 3.5 1.1 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KFX96413.1 - 4.2e-24 84.4 0.4 8.5e-24 83.4 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KFX96413.1 - 2e-05 25.3 0.6 5.3e-05 23.9 0.6 1.8 1 0 0 1 1 1 1 Peptidase S8 pro-domain eIF3_subunit PF08597.10 KFX96415.1 - 2.5e-47 161.8 5.5 2.8e-47 161.7 5.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ANAPC_CDC26 PF10471.9 KFX96419.1 - 1.2e-12 48.5 3.5 1.5e-12 48.2 3.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Rnk_N PF14760.6 KFX96419.1 - 9.3 6.8 7.7 47 4.6 7.7 2.0 1 1 0 1 1 1 0 Rnk N-terminus Urm1 PF09138.11 KFX96436.1 - 6.4e-22 77.7 0.1 4.7e-16 58.9 0.1 2.0 1 1 1 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KFX96436.1 - 0.011 16.3 0.0 0.013 16.1 0.0 1.3 1 1 0 1 1 1 0 ThiS family zf-C2H2 PF00096.26 KFX96437.1 - 3.1e-14 52.5 18.0 3.2e-05 24.2 1.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX96437.1 - 2.4e-09 37.2 21.6 4.9e-09 36.2 0.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX96437.1 - 1.6e-06 28.5 16.0 0.072 14.0 0.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFX96437.1 - 0.015 15.4 4.8 0.029 14.5 0.5 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 KFX96437.1 - 0.024 15.0 0.6 3.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GAGA PF09237.11 KFX96437.1 - 0.046 13.5 1.2 5.8 6.8 0.2 2.6 1 1 1 2 2 2 0 GAGA factor zf-C2H2_8 PF15909.5 KFX96437.1 - 0.054 13.8 4.3 1.2 9.5 1.5 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 KFX96437.1 - 0.065 13.4 3.2 1e+02 3.1 0.1 4.2 3 1 1 4 4 4 0 Zic proteins zinc finger domain Fer2 PF00111.27 KFX96437.1 - 0.11 12.5 0.3 0.32 11.0 0.3 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TFIIA PF03153.13 KFX96437.1 - 0.14 12.2 7.6 0.18 11.8 7.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 KFX96437.1 - 3.1 7.8 6.9 4.5 7.3 2.9 2.3 2 0 0 2 2 2 0 zinc-RING finger domain GTP_EFTU PF00009.27 KFX96453.1 - 2e-58 197.1 0.3 3.2e-58 196.5 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFX96453.1 - 6.8e-34 116.3 0.1 1.4e-33 115.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFX96453.1 - 2.6e-33 114.0 0.0 5.2e-33 113.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFX96453.1 - 1.2e-24 86.1 0.0 2e-23 82.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX96453.1 - 5.4e-13 49.1 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFX96453.1 - 3.6e-07 30.1 0.0 7.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KFX96453.1 - 0.1 13.1 0.0 3.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KFX96453.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2569 PF10754.9 KFX96454.1 - 0.012 16.1 0.2 0.012 16.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Abhydrolase_6 PF12697.7 KFX96455.1 - 4.2e-05 24.3 3.1 4.2e-05 24.3 3.1 1.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX96455.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFX96455.1 - 0.019 14.8 0.2 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KFX96455.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Terminase_6 PF03237.15 KFX96455.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family Abhydrolase_5 PF12695.7 KFX96455.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 KFX96456.1 - 7.8e-52 176.3 0.0 1.1e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fructosamin_kin PF03881.14 KFX96456.1 - 5.1e-41 140.8 0.1 7.3e-41 140.3 0.1 1.1 1 0 0 1 1 1 1 Fructosamine kinase Herpes_IR6 PF06307.12 KFX96456.1 - 0.11 12.0 0.3 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus IR6 protein Frtz PF11768.8 KFX96457.1 - 1.3e-06 27.0 0.0 0.013 13.9 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KFX96457.1 - 2.1e-06 28.4 0.2 0.9 10.5 0.0 6.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96457.1 - 5.3e-06 26.6 0.0 0.84 10.0 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KFX96457.1 - 4.3e-05 23.5 0.1 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.14 KFX96457.1 - 0.00034 20.2 0.0 0.00092 18.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX96457.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX96457.1 - 0.0097 16.5 0.0 0.024 15.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family VID27 PF08553.10 KFX96457.1 - 0.12 11.4 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DAO PF01266.24 KFX96458.1 - 2e-31 109.8 1.2 2.4e-31 109.6 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX96458.1 - 0.0083 16.3 0.2 0.023 14.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX96458.1 - 0.01 15.8 0.1 0.047 13.7 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_transf_54 PF04666.13 KFX96459.1 - 4.4e-08 32.3 0.0 0.0064 15.4 0.1 3.0 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region EF-hand_6 PF13405.6 KFX96459.1 - 1.5e-05 24.5 0.4 4.1e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KFX96459.1 - 1.8e-05 23.9 0.3 4.7e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFX96459.1 - 0.0013 19.2 0.2 0.0046 17.4 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFX96459.1 - 0.0016 17.8 0.5 0.0032 16.9 0.5 1.5 1 0 0 1 1 1 1 EF hand Type_ISP_C PF18135.1 KFX96459.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Type ISP C-terminal specificity domain Glyco_transf_25 PF01755.17 KFX96459.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) ADH_zinc_N_2 PF13602.6 KFX96460.1 - 1.3e-27 97.5 0.4 2.5e-27 96.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX96460.1 - 3.9e-17 62.4 0.2 1.1e-16 61.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX96460.1 - 3.7e-06 26.8 0.0 1.3e-05 25.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KFX96460.1 - 0.063 13.5 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 KFX96461.1 - 3.2e-46 157.9 0.6 4.7e-46 157.4 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX96461.1 - 2.2e-20 73.0 0.5 2.2e-20 73.0 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFX96461.1 - 6e-20 71.6 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Lycopene_cycl PF05834.12 KFX96461.1 - 5.6e-08 32.2 9.3 0.022 13.8 0.2 3.2 3 0 0 3 3 3 3 Lycopene cyclase protein GIDA PF01134.22 KFX96461.1 - 9e-08 31.6 11.8 0.0018 17.4 0.8 3.8 2 1 2 4 4 4 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFX96461.1 - 1.9e-07 30.7 0.6 3.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX96461.1 - 1.4e-05 24.0 11.4 0.0042 15.9 0.5 3.2 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 KFX96461.1 - 0.00024 21.0 3.4 0.02 14.8 0.3 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFX96461.1 - 0.00041 19.5 7.1 0.014 14.5 0.8 2.6 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 KFX96461.1 - 0.0012 19.3 0.7 0.011 16.1 0.2 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX96461.1 - 0.0039 16.6 0.0 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KFX96461.1 - 0.004 16.3 0.0 0.037 13.2 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX96461.1 - 0.0049 17.1 4.5 1.2 9.4 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KFX96461.1 - 0.0075 15.9 2.6 0.033 13.8 0.2 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KFX96461.1 - 0.044 13.0 1.5 0.49 9.6 0.1 2.4 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 KFX96461.1 - 0.084 12.2 1.1 0.17 11.2 0.1 2.0 3 0 0 3 3 3 0 ThiF family DAO PF01266.24 KFX96461.1 - 0.33 10.5 14.9 0.73 9.3 0.1 3.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase zf-C2H2 PF00096.26 KFX96462.1 - 5.5e-11 42.3 28.4 0.0033 17.8 3.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX96462.1 - 1.4e-09 38.0 24.2 0.0057 17.4 3.4 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX96462.1 - 0.00034 20.5 2.3 0.00034 20.5 2.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX96462.1 - 0.021 15.2 25.9 0.12 12.8 1.1 4.8 4 0 0 4 4 4 0 Zinc-finger double domain DUF2527 PF10736.9 KFX96462.1 - 5.4 6.9 8.4 16 5.4 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) SKG6 PF08693.10 KFX96463.1 - 2.3e-05 23.7 0.2 4.4e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KFX96463.1 - 0.03 14.3 1.9 0.077 13.0 1.9 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif CAP59_mtransfer PF11735.8 KFX96466.1 - 3.9e-67 226.4 0.0 4.9e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ATP-synt_ab PF00006.25 KFX96467.1 - 3.9e-61 206.4 0.0 6e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFX96467.1 - 4.1e-23 81.7 0.4 1.1e-22 80.3 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KFX96467.1 - 0.012 16.0 0.0 0.6 10.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFX96467.1 - 0.018 15.0 0.8 0.033 14.1 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KFX96467.1 - 0.023 13.9 0.3 0.12 11.5 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 KFX96467.1 - 0.032 13.6 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KFX96467.1 - 0.032 14.1 0.0 0.071 13.0 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFX96467.1 - 0.034 14.5 1.2 0.55 10.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX96467.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFX96467.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Alpha-amylase_C PF02806.18 KFX96468.1 - 4.3e-25 88.0 0.0 9.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KFX96468.1 - 8.6e-20 70.9 0.1 2.4e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFX96468.1 - 2.6e-15 56.8 0.2 9e-12 45.2 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFX96468.1 - 0.12 11.4 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 KFX96469.1 - 5.9e-37 127.4 0.0 1.8e-36 125.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFX96469.1 - 5.2e-12 46.3 0.0 8.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFX96469.1 - 3.8e-08 33.3 0.0 9.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFX96469.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX96469.1 - 0.00038 20.7 0.3 0.0037 17.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX96469.1 - 0.00041 20.8 0.0 0.0016 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 KFX96469.1 - 0.00067 18.8 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 KFX96469.1 - 0.0038 17.0 0.7 0.0084 15.9 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFX96469.1 - 0.0069 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KFX96469.1 - 0.0097 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KFX96469.1 - 0.024 14.3 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFX96469.1 - 0.04 13.3 0.1 4.6 6.6 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KFX96469.1 - 0.046 13.5 0.2 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFX96469.1 - 0.049 14.2 0.2 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFX96469.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFX96469.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX96469.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX96469.1 - 0.084 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KFX96469.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KFX96469.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KFX96469.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KFX96469.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Bac_DnaA PF00308.18 KFX96469.1 - 0.18 11.7 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.12 KFX96469.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain COX4 PF02936.14 KFX96470.1 - 4.4e-48 162.8 0.0 6.6e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KFX96470.1 - 0.019 15.4 2.4 0.036 14.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Gp_dh_C PF02800.20 KFX96471.1 - 6e-70 233.9 0.7 1e-69 233.2 0.7 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFX96471.1 - 2.8e-37 127.1 0.0 7.8e-37 125.7 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX96471.1 - 0.074 12.4 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Molybdopterin PF00384.22 KFX96472.1 - 1.8e-74 251.3 0.0 1.1e-72 245.4 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 KFX96472.1 - 2e-19 70.0 0.0 4.9e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 KFX96472.1 - 2.4e-19 69.1 0.1 6.6e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KFX96472.1 - 2.2e-17 62.3 0.2 2.2e-17 62.3 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KFX96472.1 - 1.5e-07 31.3 0.4 1.5e-07 31.3 0.4 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFX96472.1 - 0.059 13.1 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pox_A_type_inc PF04508.12 KFX96473.1 - 0.2 11.6 1.9 0.36 10.7 1.9 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat RRM_3 PF08777.11 KFX96474.1 - 0.2 11.7 1.6 0.32 11.1 1.6 1.2 1 0 0 1 1 1 0 RNA binding motif MHYT PF03707.16 KFX96490.1 - 5.6e-23 80.9 22.4 1.3e-10 41.3 1.1 5.6 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat Oxidored_q2 PF00420.24 KFX96490.1 - 0.18 11.4 2.4 0.56 9.9 2.5 1.9 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM154 PF15102.6 KFX96490.1 - 0.24 11.3 0.1 0.46 10.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4131 PF13567.6 KFX96490.1 - 6.5 6.4 11.4 0.27 10.9 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RskA PF10099.9 KFX96491.1 - 0.49 10.7 18.5 2.2 8.5 10.1 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Sugar_tr PF00083.24 KFX96492.1 - 4.1e-101 339.1 16.5 4.7e-101 338.9 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96492.1 - 3.9e-42 144.4 28.8 6e-35 120.8 14.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KFX96493.1 - 1.2e-10 41.3 6.0 2.2e-10 40.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_C PF02836.17 KFX96494.1 - 1.7e-108 362.3 0.0 2.3e-108 361.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFX96494.1 - 5.3e-63 212.9 0.0 9.4e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFX96494.1 - 8.9e-48 162.4 0.5 2.2e-47 161.1 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFX96494.1 - 1.2e-21 77.0 0.0 2.8e-20 72.6 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFX96494.1 - 3e-18 66.5 0.3 8.6e-18 65.0 0.3 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFX96494.1 - 0.00014 22.4 0.9 0.00084 19.9 0.0 2.7 4 0 0 4 4 4 1 Beta-galactosidase jelly roll domain NmrA PF05368.13 KFX96495.1 - 1.1e-25 90.6 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX96495.1 - 1.9e-09 37.7 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX96495.1 - 0.062 12.7 0.1 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GED PF02212.18 KFX96497.1 - 6.1e-32 109.6 2.1 8.5e-32 109.2 2.1 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain Epimerase PF01370.21 KFX96498.1 - 0.0053 16.2 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 KFX96500.1 - 8.6e-10 38.4 0.1 6.7e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S8e PF01201.22 KFX96502.1 - 2.1e-47 160.8 1.6 2.1e-47 160.8 1.6 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KFX96502.1 - 0.74 9.2 7.0 1.7 8.0 7.0 1.5 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal MscS_TM PF12794.7 KFX96502.1 - 4.9 5.9 4.1 7 5.4 4.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Y_phosphatase3 PF13350.6 KFX96503.1 - 1.3e-42 146.4 0.0 2.1e-42 145.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFX96503.1 - 8.3e-06 25.5 0.0 2.6e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX96503.1 - 0.002 17.8 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX96503.1 - 0.0021 17.9 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KFX96503.1 - 0.016 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-C2H2 PF00096.26 KFX96506.1 - 1.5e-05 25.2 12.4 0.0037 17.6 1.6 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX96506.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX96506.1 - 0.00081 20.0 11.3 0.079 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KFX96506.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) IPP-2 PF04979.14 KFX96506.1 - 0.95 10.2 6.5 0.24 12.1 2.5 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) zf-H2C2_5 PF13909.6 KFX96506.1 - 1.7 8.4 7.0 2.6 7.9 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain RasGEF PF00617.19 KFX96508.1 - 0.1 12.8 0.1 0.69 10.1 0.0 2.3 2 1 0 2 2 2 0 RasGEF domain OrsD PF12013.8 KFX96510.1 - 0.00073 20.0 0.1 0.0025 18.2 0.1 2.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DSPc PF00782.20 KFX96526.1 - 5.4e-22 78.0 0.0 1.9e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX96526.1 - 0.0066 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFX96526.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain CAML PF14963.6 KFX96533.1 - 0.034 14.3 3.3 0.065 13.4 3.3 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Choline_kinase PF01633.20 KFX96533.1 - 0.041 13.5 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 KFX96533.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cupin_1 PF00190.22 KFX96534.1 - 3.6e-18 65.6 1.2 5.4e-18 65.0 1.2 1.2 1 0 0 1 1 1 1 Cupin tify PF06200.14 KFX96534.1 - 0.0094 15.3 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 tify domain TauD PF02668.16 KFX96535.1 - 1.5e-48 166.0 0.0 1.9e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fn3-like PF14310.6 KFX96535.1 - 0.05 13.7 0.2 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Fibronectin type III-like domain Porin_7 PF16956.5 KFX96535.1 - 0.17 11.5 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 Putative general bacterial porin MFS_1 PF07690.16 KFX96536.1 - 1.8e-23 83.1 20.6 2.6e-23 82.5 20.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KFX96536.1 - 3.9e-11 42.5 0.1 8.2e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96536.1 - 3.6e-06 27.0 9.0 6.1e-06 26.2 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2104 PF09877.9 KFX96536.1 - 0.041 14.1 0.2 0.22 11.8 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF3712 PF12505.8 KFX96537.1 - 4.1e-37 127.2 4.2 7.2e-37 126.4 0.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) Cyt-b5 PF00173.28 KFX96537.1 - 6.1e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ferlin_C PF16165.5 KFX96537.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF2236 PF09995.9 KFX96538.1 - 4.4e-56 190.6 2.2 5.6e-56 190.3 2.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fungal_trans PF04082.18 KFX96540.1 - 0.039 13.0 3.6 0.16 11.0 3.6 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 KFX96541.1 - 4.6e-77 259.4 0.0 5.9e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX96541.1 - 7e-16 59.0 0.5 1.7e-15 57.8 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX96542.1 - 9.1e-33 113.6 0.3 1.5e-32 112.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX96542.1 - 2.8e-23 81.9 0.4 5.7e-23 80.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX96542.1 - 4.8e-18 65.9 0.0 1.8e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFX96542.1 - 3.2e-05 24.2 0.1 5.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.19 KFX96543.1 - 5.3e-28 97.7 0.0 3.6e-11 42.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX96543.1 - 3.6e-15 56.0 0.0 1.3e-10 41.0 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX96543.1 - 2.8e-11 43.2 0.0 1.5e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX96543.1 - 1e-05 25.5 0.2 0.0099 15.9 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX96543.1 - 3.3e-05 23.2 2.1 0.03 13.5 0.1 3.7 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX96543.1 - 5.9e-05 23.2 0.3 0.00028 21.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX96543.1 - 0.0095 15.6 3.4 0.7 9.4 0.4 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX96543.1 - 0.014 14.7 1.6 0.37 10.0 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KFX96543.1 - 0.021 14.9 0.6 0.65 10.1 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX96543.1 - 0.033 14.8 0.6 9.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX96543.1 - 0.084 12.1 0.6 0.14 11.4 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KFX96543.1 - 0.44 9.2 3.0 0.21 10.3 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KFX96544.1 - 2.5e-32 112.2 24.3 4e-32 111.5 24.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I68 PF10468.9 KFX96545.1 - 0.24 11.8 0.5 0.24 11.8 0.5 1.8 2 1 0 2 2 2 0 Carboxypeptidase inhibitor I68 BATS PF06968.13 KFX96546.1 - 7.1e-22 77.4 0.1 3.5e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KFX96546.1 - 1.5e-13 51.5 0.1 3.1e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily INPP5B_PH PF16776.5 KFX96546.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain APH PF01636.23 KFX96547.1 - 1.1e-11 45.2 0.0 1.6e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX96547.1 - 2.2e-08 34.0 0.0 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFX96547.1 - 0.016 14.6 0.0 2.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 KFX96547.1 - 0.088 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WWamide PF08258.11 KFX96547.1 - 1.3 9.6 4.7 4.3 8.0 4.7 2.0 1 0 0 1 1 1 0 WWamide peptide HET PF06985.11 KFX96548.1 - 9e-29 100.7 0.1 1.4e-28 100.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 KFX96549.1 - 4.6e-11 43.1 0.5 3.1e-09 37.1 0.5 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX96549.1 - 1.7e-05 24.5 0.0 0.00023 20.8 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase MFS_1 PF07690.16 KFX96550.1 - 6.1e-45 153.7 39.1 1.2e-44 152.7 39.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX96550.1 - 1.4e-10 40.2 11.4 1.4e-10 40.2 11.4 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KFX96551.1 - 2.8e-17 62.6 0.0 4.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96551.1 - 7.9e-10 38.7 10.8 1.7e-09 37.7 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Uso1_p115_C PF04871.13 KFX96551.1 - 0.14 12.5 0.2 0.24 11.8 0.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_23 PF13489.6 KFX96552.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96552.1 - 1.2e-10 41.9 0.0 2.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX96552.1 - 2.4e-08 34.5 0.0 4.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX96552.1 - 1.4e-06 28.1 0.0 1.7e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX96552.1 - 3e-06 27.9 0.0 1.6e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX96552.1 - 0.0044 16.6 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KFX96552.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KFX96552.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KFX96552.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KFX96552.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KFX96552.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 KFX96553.1 - 9.1e-58 196.1 0.0 1.2e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.21 KFX96554.1 - 3.5e-31 108.3 0.0 1.4e-13 50.3 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III CLP_protease PF00574.23 KFX96556.1 - 3.2e-71 239.0 0.0 5.2e-71 238.3 0.0 1.3 1 1 0 1 1 1 1 Clp protease AbbA_antirepres PF14156.6 KFX96557.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Antirepressor AbbA TPR_17 PF13431.6 KFX96558.1 - 0.00013 22.1 0.6 0.46 11.0 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX96558.1 - 0.037 13.7 0.7 11 5.8 0.0 3.7 4 0 0 4 4 4 0 TPR repeat Nro1 PF12753.7 KFX96558.1 - 0.074 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 TPR_19 PF14559.6 KFX96558.1 - 0.13 12.8 2.3 27 5.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96558.1 - 0.31 12.0 13.9 3 8.9 0.0 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX96558.1 - 0.78 10.0 6.5 47 4.5 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX96558.1 - 1.1 10.1 0.1 1.1 10.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX96558.1 - 1.1 9.4 3.4 94 3.4 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.28 KFX96559.1 - 2.7e-18 66.3 0.0 3.5e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KFX96560.1 - 2.4e-12 46.8 0.0 8.1e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX96560.1 - 4.7e-08 33.2 0.0 1.5e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX96560.1 - 3.5e-07 29.8 0.0 7.3e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFX96560.1 - 1.1e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFX96560.1 - 5.4e-06 25.9 0.0 3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFX96560.1 - 0.00091 18.4 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 KFX96560.1 - 0.0073 15.9 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KFX96560.1 - 0.01 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KFX96560.1 - 0.01 14.6 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KFX96560.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_28 PF00295.17 KFX96561.1 - 2.9e-53 181.0 12.8 5.1e-53 180.2 12.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.8 KFX96561.1 - 0.098 12.4 0.5 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DJ-1_PfpI PF01965.24 KFX96562.1 - 3e-13 49.9 0.0 4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_11 PF00457.17 KFX96563.1 - 3.2e-78 261.5 22.9 3.7e-78 261.2 22.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Cytochrom_B561 PF03188.16 KFX96564.1 - 0.00017 21.8 4.8 0.00031 20.9 4.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3824 PF12868.7 KFX96564.1 - 0.0013 19.4 9.4 0.0013 19.4 9.4 6.2 5 2 1 6 6 6 2 Domain of unknwon function (DUF3824) DUF4079 PF13301.6 KFX96564.1 - 0.024 14.8 1.5 0.024 14.8 1.5 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF4271 PF14093.6 KFX96564.1 - 0.22 11.4 10.3 0.14 12.1 6.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Plant_vir_prot PF01307.17 KFX96564.1 - 1.6 9.0 3.6 1.2 9.4 0.1 2.6 3 0 0 3 3 3 0 Plant viral movement protein GCD14_N PF14801.6 KFX96568.1 - 0.0053 16.6 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term NACHT PF05729.12 KFX96574.1 - 3.7e-09 36.7 0.2 1.1e-08 35.1 0.2 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX96574.1 - 6e-09 36.5 0.1 2e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFX96574.1 - 3e-07 30.5 0.1 1.4e-05 25.2 0.1 2.7 1 1 0 1 1 1 1 AAA domain Ank_2 PF12796.7 KFX96574.1 - 5.4e-05 23.7 0.0 0.0017 18.9 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) NB-ARC PF00931.22 KFX96574.1 - 0.00014 21.1 0.0 0.00042 19.6 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KFX96574.1 - 0.0009 19.5 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 KFX96574.1 - 0.011 14.9 0.1 0.029 13.6 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 KFX96574.1 - 0.022 14.3 0.2 0.19 11.2 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFX96574.1 - 0.044 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX96574.1 - 0.051 13.3 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 KFX96574.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 KFX96574.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KFX96574.1 - 0.11 12.4 0.2 0.32 10.9 0.2 1.8 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 KFX96574.1 - 0.12 11.5 0.4 0.28 10.3 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_19 PF13245.6 KFX96574.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain PSRP-3_Ycf65 PF04839.13 KFX96574.1 - 0.17 12.1 0.7 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Cupin_2 PF07883.11 KFX96576.1 - 0.0012 18.6 0.0 0.0041 16.8 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Rep_fac-A_3 PF08661.11 KFX96577.1 - 7.6e-25 87.3 0.0 8.3e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA-synt_2 PF00152.20 KFX96578.1 - 2.8e-79 266.5 0.4 4.1e-79 265.9 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFX96578.1 - 9e-10 38.4 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFX96578.1 - 2.4e-06 27.2 0.1 0.0045 16.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FPP PF05911.11 KFX96584.1 - 0.17 10.1 17.8 0.11 10.7 16.0 1.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tho2 PF11262.8 KFX96584.1 - 4.5 6.4 7.5 1.5 8.0 2.2 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.11 KFX96584.1 - 6.4 7.4 9.9 16 6.1 7.7 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 KFX96584.1 - 6.6 6.8 16.0 15 5.7 7.6 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Pyr_redox_2 PF07992.14 KFX96585.1 - 6.4e-52 176.6 1.6 1e-51 175.9 1.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX96585.1 - 1.2e-15 57.9 1.9 8.1e-14 52.0 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFX96585.1 - 1.7e-15 56.7 0.1 8.2e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 KFX96585.1 - 3.9e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KFX96585.1 - 0.00052 19.3 0.0 0.88 8.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.6 KFX96585.1 - 0.00074 19.4 0.0 0.008 16.1 0.0 2.6 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.11 KFX96585.1 - 0.0011 18.6 0.1 0.0025 17.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 KFX96585.1 - 0.0037 17.3 0.5 0.53 10.3 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX96585.1 - 0.0076 15.0 1.6 0.2 10.3 0.0 3.0 3 1 1 4 4 4 1 HI0933-like protein Trp_halogenase PF04820.14 KFX96585.1 - 0.027 13.3 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FIST PF08495.10 KFX96585.1 - 0.048 13.7 0.1 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 FIST N domain TrkA_N PF02254.18 KFX96585.1 - 0.16 12.2 0.6 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain DUF3237 PF11578.8 KFX96589.1 - 7e-33 113.6 0.0 7.8e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.17 KFX96590.1 - 1.3e-41 142.4 0.0 4.8e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 KFX96591.1 - 2.9e-33 115.0 0.1 2.9e-33 115.0 0.1 1.9 2 0 0 2 2 2 1 Leo1-like protein CHORD PF04968.12 KFX96592.1 - 8.8e-49 164.1 20.6 9.5e-26 90.3 9.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KFX96592.1 - 2.9e-12 47.4 0.0 4.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 CS domain HeLo PF14479.6 KFX96593.1 - 1.3e-42 146.0 0.0 1e-41 143.1 0.0 2.0 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KFX96593.1 - 0.19 11.0 0.0 5 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase SURF4 PF02077.15 KFX96594.1 - 7.5e-97 324.1 5.4 9.1e-97 323.8 5.4 1.1 1 0 0 1 1 1 1 SURF4 family WH2 PF02205.20 KFX96594.1 - 2.1e-10 40.1 1.9 8.4e-10 38.2 1.9 2.1 1 0 0 1 1 1 1 WH2 motif DUF1643 PF07799.12 KFX96595.1 - 0.028 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) NIR_SIR PF01077.22 KFX96595.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain BOP1NT PF08145.12 KFX96596.1 - 8.5e-103 343.8 8.4 1.2e-102 343.3 8.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFX96596.1 - 2.8e-24 84.9 2.4 5.9e-10 39.6 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96596.1 - 5.4e-07 29.8 0.1 0.0017 18.6 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3947 PF13135.6 KFX96596.1 - 0.15 12.3 0.2 0.42 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Tannase PF07519.11 KFX96597.1 - 8.4e-79 265.6 0.1 2.3e-77 260.9 0.1 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KFX96597.1 - 0.00024 20.7 0.1 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX96597.1 - 0.0028 17.0 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX96597.1 - 0.0065 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFX96597.1 - 0.093 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Serglycin PF04360.12 KFX96598.1 - 0.21 11.5 3.0 0.16 11.9 0.4 2.0 2 0 0 2 2 2 0 Serglycin DUF3336 PF11815.8 KFX96599.1 - 6.9e-36 123.0 0.1 8.9e-35 119.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFX96599.1 - 9.9e-14 52.0 1.0 2.8e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase HpcH_HpaI PF03328.14 KFX96600.1 - 4.8e-33 114.2 0.0 6.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Radical_SAM PF04055.21 KFX96600.1 - 0.065 13.6 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily Cellulase PF00150.18 KFX96602.1 - 7.4e-08 32.2 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4399 PF14347.6 KFX96602.1 - 0.039 14.3 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) CPL PF08144.11 KFX96604.1 - 1.4e-34 119.5 13.7 2.3e-32 112.3 0.0 5.5 4 1 0 4 4 4 1 CPL (NUC119) domain CTI PF06934.11 KFX96604.1 - 0.04 12.5 0.1 0.094 11.2 0.1 1.5 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DUF3206 PF11472.8 KFX96604.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) TFIIF_alpha PF05793.12 KFX96604.1 - 0.15 10.6 36.4 0.016 13.8 24.8 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RWD PF05773.22 KFX96605.1 - 1.9e-24 86.2 0.2 3.6e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KFX96605.1 - 0.00012 22.5 12.4 0.00041 20.8 12.4 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF488 PF04343.13 KFX96605.1 - 0.31 11.6 3.0 0.59 10.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF488 XRN_M PF17846.1 KFX96605.1 - 0.41 9.5 4.7 0.52 9.2 4.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TPX2 PF06886.11 KFX96605.1 - 4.6 7.5 22.1 0.098 12.9 10.5 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) TPR_8 PF13181.6 KFX96606.1 - 3.2e-15 55.0 0.0 8.1e-07 28.8 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX96606.1 - 1.2e-12 48.0 0.9 1.8e-06 28.1 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX96606.1 - 1.3e-11 43.7 0.8 7.3e-05 22.6 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX96606.1 - 9.1e-11 42.1 2.5 0.033 14.7 0.5 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX96606.1 - 1.1e-10 42.0 0.4 0.00022 21.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96606.1 - 2.5e-10 40.3 7.8 0.036 14.9 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX96606.1 - 2.9e-09 36.8 1.7 1.4e-05 24.7 0.1 2.7 1 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KFX96606.1 - 1.8e-08 33.8 4.4 0.001 18.9 0.1 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX96606.1 - 7e-08 32.0 0.2 0.00031 20.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX96606.1 - 4.7e-05 23.1 5.9 0.12 12.3 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX96606.1 - 0.00019 21.8 1.8 2 9.2 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX96606.1 - 0.00061 19.9 2.5 1.5 9.0 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFX96606.1 - 0.0036 17.6 0.5 2.3 8.6 0.0 3.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFX96606.1 - 0.0095 16.5 10.1 2.1 9.2 0.1 5.1 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX96606.1 - 0.0095 15.6 1.1 1.2 8.9 0.1 3.8 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 KFX96606.1 - 0.016 15.6 0.0 55 4.5 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF29 PF01724.16 KFX96606.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF29 Rad51 PF08423.11 KFX96608.1 - 9.5e-130 431.4 0.0 1.2e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFX96608.1 - 1.2e-09 38.1 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFX96608.1 - 6.8e-08 32.3 0.0 9.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFX96608.1 - 6.3e-06 26.7 0.5 2e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFX96608.1 - 6.8e-06 25.6 0.1 2e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KFX96608.1 - 0.016 14.6 0.1 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFX96608.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFX96608.1 - 0.13 12.3 0.4 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KFX96608.1 - 0.15 11.2 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 KFX96609.1 - 5.8e-141 470.8 0.0 7.5e-141 470.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_L29 PF00831.23 KFX96610.1 - 1.1e-16 60.5 0.4 1.1e-16 60.5 0.4 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein V-SNARE_C PF12352.8 KFX96611.1 - 1.3e-14 54.2 0.3 1.3e-14 54.2 0.3 3.2 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus PA28_beta PF02252.18 KFX96611.1 - 0.037 13.7 0.3 0.081 12.6 0.3 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit Wzy_C_2 PF11846.8 KFX96611.1 - 0.15 11.9 0.3 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal GLTSCR1 PF15249.6 KFX96611.1 - 0.2 12.1 2.6 0.28 11.7 1.5 1.8 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein STAT_alpha PF01017.20 KFX96611.1 - 0.29 11.0 7.3 0.066 13.1 2.6 2.1 2 1 1 3 3 3 0 STAT protein, all-alpha domain DivIC PF04977.15 KFX96611.1 - 3.3 7.5 8.7 28 4.6 2.0 3.4 3 1 1 4 4 4 0 Septum formation initiator Snapin_Pallidin PF14712.6 KFX96611.1 - 4 7.9 12.4 0.41 11.1 6.7 2.2 3 0 0 3 3 3 0 Snapin/Pallidin ATP-synt_10 PF05176.14 KFX96612.1 - 6.4e-61 205.8 0.0 7.2e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Peptidase_C14 PF00656.22 KFX96621.1 - 1.4e-61 208.6 0.0 2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KFX96621.1 - 0.1 12.5 0.4 0.66 9.9 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cnn_1N PF07989.11 KFX96622.1 - 1.2e-25 89.5 3.3 1.2e-25 89.5 3.3 14.2 6 2 5 12 12 12 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KFX96622.1 - 1.1e-23 83.6 0.1 1.1e-23 83.6 0.1 5.1 5 0 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 KFX96622.1 - 0.00015 21.8 14.4 0.00015 21.8 14.4 11.6 2 2 5 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFX96622.1 - 0.00018 20.5 189.3 0.013 14.4 20.9 8.5 1 1 7 9 9 9 7 Spc7 kinetochore protein Fez1 PF06818.15 KFX96622.1 - 0.0031 18.0 173.9 0.0035 17.8 24.8 8.6 1 1 8 9 9 9 4 Fez1 Spc110_C PF18520.1 KFX96622.1 - 0.12 12.0 0.7 0.8 9.4 0.1 2.7 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain SGT1 PF07093.11 KFX96623.1 - 9.5e-95 318.2 18.2 3e-84 283.6 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein BSP_II PF05432.11 KFX96623.1 - 4.7 6.8 15.4 8.1 6.0 15.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) APH PF01636.23 KFX96624.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family THUMP PF02926.17 KFX96625.1 - 1.5e-07 31.6 0.1 3.5e-06 27.2 0.0 2.4 2 1 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.18 KFX96626.1 - 1.7e-31 109.2 0.0 2.8e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX96626.1 - 2.4e-20 72.7 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFX96626.1 - 9.7e-14 51.4 0.0 2.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KFX96626.1 - 0.035 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Pkinase PF00069.25 KFX96627.1 - 6.6e-61 206.0 0.0 2.2e-60 204.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96627.1 - 2.3e-45 154.9 0.0 4.2e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96627.1 - 1.6e-09 37.5 0.0 5.5e-06 25.9 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFX96627.1 - 0.0012 17.7 0.5 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFX96627.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX96627.1 - 0.097 12.6 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribophorin_II PF05817.14 KFX96628.1 - 6.9e-18 64.6 0.0 8.3e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 KFX96628.1 - 0.074 13.2 0.9 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 PufQ cytochrome subunit Iso_dh PF00180.20 KFX96629.1 - 1.5e-97 326.8 0.0 2.1e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acetyltransf_4 PF13420.7 KFX96630.1 - 0.095 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KFX96631.1 - 6.9e-20 71.3 24.3 9.4e-20 70.8 24.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX96631.1 - 0.71 8.7 14.9 1.2 7.9 14.9 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter Glyco_hydr_30_2 PF14587.6 KFX96632.1 - 9e-13 48.6 3.3 2.1e-09 37.5 0.0 2.7 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KFX96632.1 - 1.9e-10 40.8 4.0 5.1e-10 39.4 4.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFX96632.1 - 8.6e-09 35.0 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 KFX96632.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain CBM_1 PF00734.18 KFX96632.1 - 0.24 11.4 15.3 0.83 9.7 15.3 2.0 1 0 0 1 1 1 0 Fungal cellulose binding domain TPR_10 PF13374.6 KFX96633.1 - 0.0065 16.3 0.2 3.9 7.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat APG6_N PF17675.1 KFX96633.1 - 0.011 16.3 6.4 0.011 16.3 6.4 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region TPR_12 PF13424.6 KFX96633.1 - 0.024 14.9 0.6 4.6 7.6 0.1 4.2 4 2 2 6 6 6 0 Tetratricopeptide repeat O-FucT PF10250.9 KFX96634.1 - 3.3e-10 40.2 0.0 3.1e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1030 PF06270.11 KFX96634.1 - 0.15 11.8 0.6 0.4 10.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) Ank_2 PF12796.7 KFX96636.1 - 5.9e-97 318.4 0.5 8.8e-14 51.9 0.1 8.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX96636.1 - 1.2e-61 197.4 0.0 0.0016 18.8 0.0 15.2 15 1 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.6 KFX96636.1 - 9.4e-61 201.5 8.1 2.7e-08 34.2 0.0 10.2 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank PF00023.30 KFX96636.1 - 8.3e-58 190.5 0.0 0.015 15.7 0.0 15.9 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 KFX96636.1 - 4.1e-49 164.0 7.9 9.4e-07 29.0 0.1 11.8 4 3 6 12 12 12 8 Ankyrin repeats (many copies) NACHT PF05729.12 KFX96636.1 - 6e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SfsA PF03749.13 KFX96636.1 - 0.0035 17.2 0.5 85 3.0 0.0 5.8 4 2 3 7 7 7 0 Sugar fermentation stimulation protein RE domain AAA_22 PF13401.6 KFX96636.1 - 0.0068 16.7 0.0 0.025 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Helo_like_N PF17111.5 KFX96636.1 - 0.019 14.3 2.9 0.035 13.5 2.9 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Met_10 PF02475.16 KFX96637.1 - 0.00014 21.7 0.0 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein hNIFK_binding PF12196.8 KFX96638.1 - 0.00044 19.7 0.2 0.00069 19.1 0.2 1.3 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK Myb_DNA-bind_6 PF13921.6 KFX96640.1 - 5.4e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX96640.1 - 0.002 18.3 1.2 0.0048 17.1 1.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KFX96640.1 - 2.8 8.1 4.7 4.6 7.4 4.7 1.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain APH PF01636.23 KFX96641.1 - 3.8e-18 66.3 0.1 5e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX96641.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KFX96641.1 - 0.0048 16.3 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFX96641.1 - 0.049 13.2 0.0 0.083 12.5 0.0 1.4 1 1 0 1 1 1 0 RIO1 family NAD_kinase PF01513.21 KFX96642.1 - 2.6e-78 263.2 0.0 4.4e-78 262.4 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KFX96643.1 - 5.4e-14 52.8 0.2 8.3e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFX96643.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 KFX96644.1 - 8.5e-114 380.1 0.0 1e-113 379.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FAA_hydrolase PF01557.18 KFX96645.1 - 8.6e-64 215.2 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.15 KFX96646.1 - 6.8e-18 64.5 2.3 8e-18 64.3 2.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFX96646.1 - 3.1e-05 24.6 1.0 3.5e-05 24.5 1.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like HSF_DNA-bind PF00447.17 KFX96650.1 - 7e-29 100.3 0.4 1.3e-28 99.4 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding APC_u15 PF16636.5 KFX96650.1 - 0.0065 16.9 0.0 0.026 15.0 0.0 2.0 1 0 0 1 1 1 1 Unstructured region on APC between APC_crr regions 5 and 6 JHY PF15261.6 KFX96650.1 - 0.57 10.9 4.3 0.64 10.7 1.5 2.5 2 1 0 2 2 2 0 Jhy protein Amidase PF01425.21 KFX96651.1 - 3.2e-72 243.9 0.1 2.5e-71 241.0 0.1 1.9 1 1 0 1 1 1 1 Amidase Histone PF00125.24 KFX96652.1 - 3.7e-18 66.1 0.0 4.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFX96652.1 - 1.1e-12 47.5 0.1 2.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFX96652.1 - 3.4e-05 24.0 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.10 KFX96652.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 Neugrin PF06413.11 KFX96654.1 - 1.5e-10 41.5 0.8 1.5e-10 41.5 0.8 2.0 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.7 KFX96654.1 - 0.0001 22.5 4.1 0.0001 22.5 4.1 2.3 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 HLH PF00010.26 KFX96658.1 - 3.2e-09 36.6 0.1 6.1e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SWIRM-assoc_2 PF16496.5 KFX96658.1 - 1.3 7.8 8.1 1.6 7.5 8.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Med21 PF11221.8 KFX96658.1 - 1.5 9.1 7.4 2.4 8.4 0.4 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AKAP7_NLS PF10469.9 KFX96660.1 - 1.2e-07 31.8 0.0 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DHHC PF01529.20 KFX96667.1 - 8.4e-36 123.0 0.9 8.4e-36 123.0 0.9 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase YhhN PF07947.14 KFX96667.1 - 0.025 14.2 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 YhhN family Sugar_tr PF00083.24 KFX96671.1 - 8.2e-68 229.3 7.4 9.3e-68 229.1 7.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96671.1 - 3.1e-24 85.5 2.4 4.6e-24 85.0 2.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX96671.1 - 1.2e-06 27.4 2.3 1.3e-05 24.0 0.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KFX96671.1 - 1.5e-05 23.5 3.4 0.0028 16.0 0.8 2.2 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KFX96671.1 - 0.02 13.8 1.3 0.028 13.3 1.3 1.3 1 0 0 1 1 1 0 POT family AAA_22 PF13401.6 KFX96672.1 - 0.00018 21.8 0.1 0.54 10.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 KFX96672.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KFX96672.1 - 0.04 14.3 0.0 2.6 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_10 PF12846.7 KFX96672.1 - 0.045 12.7 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Zot PF05707.12 KFX96672.1 - 0.052 13.2 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 KFX96672.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 KFX96672.1 - 0.15 12.1 0.0 3.1 7.8 0.0 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain SATase_N PF06426.14 KFX96672.1 - 0.16 12.4 1.5 6.4 7.2 0.8 2.9 3 0 0 3 3 3 0 Serine acetyltransferase, N-terminal TauD PF02668.16 KFX96674.1 - 5.5e-60 203.4 0.6 7.7e-60 203.0 0.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aldolase_II PF00596.21 KFX96675.1 - 1.9e-46 158.3 0.3 1.9e-46 158.3 0.3 1.5 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KFX96675.1 - 4.2e-13 49.0 26.7 6.7e-13 48.3 26.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KFX96675.1 - 0.11 10.5 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynamin_M PF01031.20 KFX96679.1 - 1.6e-110 368.8 0.0 2.6e-110 368.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFX96679.1 - 5.3e-57 192.5 0.4 1.1e-56 191.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFX96679.1 - 3e-05 24.1 0.2 0.00073 19.6 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KFX96679.1 - 0.13 12.5 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SH3_9 PF14604.6 KFX96680.1 - 1.9e-28 98.0 3.3 9.3e-14 51.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFX96680.1 - 2.9e-26 90.8 5.1 1.2e-13 50.4 0.4 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KFX96680.1 - 2.1e-16 59.8 0.0 4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KFX96680.1 - 1.6e-15 56.5 0.0 7.1e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain F-box-like PF12937.7 KFX96681.1 - 0.037 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KFX96681.1 - 0.038 13.9 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 F-box domain Tyrosinase PF00264.20 KFX96682.1 - 5.2e-51 174.1 1.7 7.3e-51 173.6 1.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3405 PF11885.8 KFX96694.1 - 1.9e-119 399.6 0.4 2.6e-119 399.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Nefa_Nip30_N PF10187.9 KFX96695.1 - 7.5e-33 113.0 6.7 7.5e-33 113.0 6.7 2.6 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2613 PF11021.8 KFX96695.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) DUF572 PF04502.13 KFX96695.1 - 0.051 13.2 16.5 0.067 12.8 16.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) UVR PF02151.19 KFX96695.1 - 1.8 8.4 8.5 0.16 11.8 2.9 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif FUSC PF04632.12 KFX96695.1 - 6.4 5.2 6.4 6.7 5.1 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aldo_ket_red PF00248.21 KFX96696.1 - 2.8e-46 158.0 0.0 1.1e-44 152.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PI-PLC-X PF00388.19 KFX96697.1 - 3.8e-12 46.0 0.0 6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4998 PF16389.5 KFX96697.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_L10 PF00466.20 KFX96698.1 - 0.0002 21.4 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.21 KFX96699.1 - 1.5e-61 208.2 0.0 2.3e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KFX96699.1 - 1e-16 60.5 0.2 3.8e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 KFX96700.1 - 2.3e-18 65.6 5.1 2.9e-18 65.2 5.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 KFX96700.1 - 0.0016 18.0 0.9 0.79 9.4 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFX96700.1 - 0.0044 17.0 0.3 0.0057 16.6 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2197 PF09963.9 KFX96700.1 - 0.012 15.9 1.3 0.89 9.9 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) TFIIS_C PF01096.18 KFX96700.1 - 0.013 15.3 0.7 4.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.14 KFX96700.1 - 0.025 14.9 0.2 2.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.19 KFX96700.1 - 0.036 14.1 0.2 0.04 13.9 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3268 PF11672.8 KFX96700.1 - 0.09 13.1 0.2 0.59 10.5 0.2 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain LRV_FeS PF05484.11 KFX96700.1 - 0.11 12.5 1.2 0.13 12.3 0.2 1.6 1 1 1 2 2 2 0 LRV protein FeS4 cluster Zn-ribbon_8 PF09723.10 KFX96700.1 - 0.16 12.1 2.6 0.38 10.9 2.6 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 KFX96700.1 - 0.17 12.4 3.1 2 9.0 0.3 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain HEM4 PF02602.15 KFX96703.1 - 6.4e-05 22.4 0.0 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.13 KFX96704.1 - 0.00021 21.7 0.1 0.00051 20.5 0.0 1.6 2 0 0 2 2 2 1 Erv1 / Alr family TLD PF07534.16 KFX96705.1 - 3.7e-26 92.0 0.0 2.7e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 TLD Xpo1 PF08389.12 KFX96706.1 - 1.7e-07 31.4 0.6 4.2e-05 23.6 0.1 2.8 2 0 0 2 2 2 2 Exportin 1-like protein HTH_Tnp_Tc5 PF03221.16 KFX96706.1 - 0.062 13.3 0.2 19 5.4 0.3 2.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain RMI1_N PF08585.12 KFX96707.1 - 8.4e-49 166.3 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 KFX96708.1 - 6.2e-28 96.7 0.9 1e-27 96.0 0.1 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KFX96708.1 - 5.4e-08 31.9 1.9 8e-08 31.3 1.9 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 KFX96708.1 - 0.0057 16.8 0.1 0.017 15.3 0.0 1.7 1 1 1 2 2 2 1 Golgi transport complex subunit 5 DUF365 PF04033.12 KFX96708.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF365) ATP-synt_ab PF00006.25 KFX96708.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FUSC PF04632.12 KFX96708.1 - 0.47 8.9 3.5 0.66 8.4 3.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ntox1 PF15500.6 KFX96708.1 - 2.6 8.4 6.0 9.9 6.6 0.0 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 NIF3 PF01784.18 KFX96709.1 - 1.5e-56 191.8 0.0 1.9e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 KFX96710.1 - 4.8e-18 65.2 0.0 1.2e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Pro_CA PF00484.19 KFX96711.1 - 1.6e-15 57.7 0.0 2.9e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase Adaptin_N PF01602.20 KFX96713.1 - 1.1e-139 466.4 4.0 1.5e-139 465.9 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFX96713.1 - 4.3e-62 208.9 5.8 4.6e-60 202.3 0.5 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX96713.1 - 2.1e-18 66.5 0.8 1.2e-06 28.8 0.0 5.0 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KFX96713.1 - 3.8e-11 42.2 4.7 0.023 14.9 0.0 6.9 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFX96713.1 - 0.00042 20.8 0.2 0.28 11.7 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 KFX96713.1 - 0.0013 18.3 0.1 1.9 8.0 0.0 3.4 2 1 1 3 3 3 2 CLASP N terminal UNC45-central PF11701.8 KFX96713.1 - 0.0036 17.3 0.2 2.3 8.1 0.1 2.9 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KFX96713.1 - 0.03 14.3 0.6 8.5 6.6 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFX96713.1 - 0.074 13.1 0.0 7.5 6.7 0.0 3.4 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 KFX96713.1 - 2.6 7.4 4.8 19 4.6 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5578) TPR_16 PF13432.6 KFX96714.1 - 2.2e-32 111.4 37.3 2.4e-07 31.3 2.3 12.8 10 2 3 13 13 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFX96714.1 - 1.7e-30 102.7 39.5 0.0085 16.1 0.0 16.1 17 0 0 17 17 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 KFX96714.1 - 3.6e-25 88.3 20.7 0.0029 18.1 3.2 10.8 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFX96714.1 - 8.5e-24 82.2 15.2 0.17 12.3 0.0 14.8 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96714.1 - 1.2e-22 78.7 35.3 0.047 14.5 0.1 15.3 11 5 4 15 15 15 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFX96714.1 - 1.5e-22 78.4 22.9 0.0042 16.8 0.0 13.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFX96714.1 - 4.5e-22 76.4 25.4 0.13 12.5 0.0 14.5 16 0 0 16 16 16 7 Tetratricopeptide repeat TPR_11 PF13414.6 KFX96714.1 - 3.6e-18 65.0 10.9 0.00046 19.8 0.0 9.3 10 0 0 10 10 10 4 TPR repeat TPR_12 PF13424.6 KFX96714.1 - 7.4e-17 61.4 34.6 0.00071 19.8 0.1 13.0 10 4 5 15 15 14 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFX96714.1 - 2.1e-11 43.8 13.2 6.5e-05 23.0 0.1 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX96714.1 - 3.3e-09 36.8 24.8 0.05 14.3 0.0 12.7 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFX96714.1 - 2.1e-08 33.6 16.5 0.32 11.1 0.0 11.0 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFX96714.1 - 8.5e-05 22.8 9.4 3 8.2 0.0 7.6 6 2 1 8 8 8 1 Tetratricopeptide repeat TPR_22 PF18833.1 KFX96714.1 - 0.00012 22.1 0.1 0.00035 20.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX96714.1 - 0.0016 18.6 16.1 18 5.7 0.1 7.0 5 3 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KFX96714.1 - 0.0037 16.3 0.4 7.2 5.5 0.1 4.2 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 KFX96714.1 - 0.0072 16.1 0.5 4.8 6.8 0.1 2.8 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_WDAD PF04053.14 KFX96714.1 - 0.017 14.2 0.0 0.049 12.7 0.0 1.7 1 0 0 1 1 1 0 Coatomer WD associated region FAT PF02259.23 KFX96714.1 - 0.045 13.0 7.9 1.1 8.4 1.6 4.3 3 1 0 4 4 4 0 FAT domain PPTA PF01239.22 KFX96714.1 - 0.18 11.5 0.3 35 4.3 0.0 3.8 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Sel1 PF08238.12 KFX96714.1 - 0.21 12.3 4.4 3.4 8.5 0.0 4.6 4 1 0 4 4 4 0 Sel1 repeat TOM20_plant PF06552.12 KFX96714.1 - 0.9 9.3 8.3 3.9 7.2 0.0 4.6 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Glyco_hydro_5_C PF18564.1 KFX96715.1 - 5.6e-23 81.3 0.0 1.3e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KFX96715.1 - 1.5e-14 54.2 2.1 5e-09 36.0 0.6 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KFX96715.1 - 0.078 12.6 0.4 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Dynamin_N PF00350.23 KFX96716.1 - 6.8e-33 114.1 0.0 1.5e-32 113.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX96716.1 - 3.5e-26 92.1 1.3 6.5e-26 91.2 1.3 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFX96716.1 - 0.00062 19.8 0.0 0.0026 17.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX96716.1 - 0.0046 16.8 0.0 0.63 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX96716.1 - 0.11 12.2 1.4 0.18 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain GED PF02212.18 KFX96716.1 - 0.12 12.6 0.1 0.39 10.9 0.1 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain BTB PF00651.31 KFX96717.1 - 1.6e-09 38.0 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Phage_connect_1 PF05135.13 KFX96717.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein DNA_primase_S PF01896.19 KFX96718.1 - 5.6e-65 218.7 0.2 8e-65 218.2 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit HAD_SAK_1 PF10307.9 KFX96719.1 - 8.6e-78 260.8 0.0 1.2e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Lactamase_B_6 PF16661.5 KFX96721.1 - 4.8e-68 228.4 0.0 7.7e-68 227.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFX96721.1 - 2.3e-49 167.9 0.0 2.3e-49 167.9 0.0 2.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFX96721.1 - 3.3e-17 62.8 0.0 1.6e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KFX96721.1 - 7.4e-12 45.0 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFX96721.1 - 0.0065 16.0 0.2 0.045 13.2 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFX96721.1 - 0.034 14.2 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Sec23_trunk PF04811.15 KFX96722.1 - 1.8e-54 184.9 0.0 1.4e-53 182.0 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFX96722.1 - 5.8e-25 87.1 0.0 1.1e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFX96722.1 - 3.1e-17 63.1 0.0 5.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFX96722.1 - 3.9e-15 55.6 5.6 1.1e-14 54.2 5.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFX96722.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1590 PF07629.11 KFX96722.1 - 0.03 14.1 1.7 0.11 12.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Vg_Tdu PF07545.14 KFX96722.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Carbam_trans_C PF16861.5 KFX96735.1 - 4.4e-68 228.2 0.0 1.4e-67 226.5 0.0 1.8 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 KFX96735.1 - 2.3e-57 195.2 0.0 6.3e-57 193.7 0.0 1.7 1 1 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 KFX96735.1 - 0.011 15.5 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycoprotease family AMP-binding PF00501.28 KFX96736.1 - 1.4e-68 231.5 0.0 1.7e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX96736.1 - 8.9e-06 26.6 0.1 2.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KFX96737.1 - 1.6e-63 215.1 0.0 2.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KFX96738.1 - 2.6e-07 31.2 0.0 5.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX96738.1 - 5.9e-05 23.6 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SUR7 PF06687.12 KFX96741.1 - 2.8e-31 108.8 6.4 3.9e-31 108.4 6.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.14 KFX96741.1 - 0.07 13.5 6.1 0.047 14.1 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF4064 PF13273.6 KFX96741.1 - 0.37 11.1 6.7 0.56 10.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF1772 PF08592.11 KFX96741.1 - 0.62 10.4 6.8 0.35 11.2 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Trp_oprn_chp PF09534.10 KFX96741.1 - 1.8 8.3 5.8 0.23 11.2 0.7 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cyt_c_ox_IV PF12270.8 KFX96741.1 - 5.5 7.1 9.5 0.82 9.8 3.9 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV AhpC-TSA_2 PF13911.6 KFX96744.1 - 2e-09 37.6 0.0 3.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFX96744.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Peptidase_C97 PF05903.14 KFX96745.1 - 7e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 KFX96745.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 KFX96745.1 - 0.063 13.6 0.9 0.32 11.3 0.2 2.3 1 1 1 2 2 2 0 Lecithin retinol acyltransferase DUF778 PF05608.12 KFX96745.1 - 0.09 13.1 3.0 0.22 11.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF778) COPIIcoated_ERV PF07970.12 KFX96746.1 - 3.6e-36 125.1 0.6 5.2e-36 124.6 0.6 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFX96746.1 - 4.3e-23 81.5 0.0 8.2e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Syntaxin PF00804.25 KFX96747.1 - 4.1e-21 75.6 5.5 5.7e-21 75.1 5.5 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFX96747.1 - 1.6e-13 50.4 0.4 8.2e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KFX96747.1 - 5.3e-05 23.5 6.8 8.5e-05 22.9 3.6 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Bacillus_HBL PF05791.11 KFX96747.1 - 0.015 15.2 0.8 0.015 15.2 0.8 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) RPW8 PF05659.11 KFX96747.1 - 0.022 14.5 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tad PF13400.6 KFX96747.1 - 0.044 14.1 0.4 0.044 14.1 0.4 3.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like Bac_export_3 PF01313.19 KFX96747.1 - 0.048 13.6 0.2 0.077 12.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 Phage_holin_3_6 PF07332.11 KFX96747.1 - 0.057 13.5 0.1 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SNAD1 PF18744.1 KFX96747.1 - 0.057 13.3 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 BLOC1_2 PF10046.9 KFX96747.1 - 0.12 12.7 3.1 0.95 9.8 0.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_HK97_TLTM PF06120.11 KFX96747.1 - 0.2 10.8 6.8 0.39 9.8 6.8 1.5 1 1 0 1 1 1 0 Tail length tape measure protein OmpH PF03938.14 KFX96747.1 - 0.29 11.5 11.1 0.12 12.7 4.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 KFX96747.1 - 2.3 9.0 6.7 18 6.0 0.2 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) V-SNARE PF05008.15 KFX96747.1 - 4.9 7.6 9.1 0.63 10.5 0.6 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FUSC PF04632.12 KFX96747.1 - 5.3 5.5 12.4 0.47 8.9 4.4 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family Brix PF04427.18 KFX96748.1 - 3.3e-32 112.1 0.2 4.4e-32 111.8 0.2 1.2 1 0 0 1 1 1 1 Brix domain ABC_tran PF00005.27 KFX96759.1 - 1.9e-49 167.7 0.0 6.4e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX96759.1 - 2.7e-35 122.3 11.9 2e-18 67.0 2.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KFX96759.1 - 2.4e-10 40.2 0.0 0.0025 17.3 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX96759.1 - 3.5e-05 24.2 2.0 0.32 11.4 0.1 3.7 3 0 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 KFX96759.1 - 0.00021 20.5 0.0 0.071 12.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFX96759.1 - 0.00057 19.6 0.1 1.1 9.0 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX96759.1 - 0.0007 20.2 0.0 0.063 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX96759.1 - 0.0018 18.4 0.2 0.12 12.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX96759.1 - 0.002 18.0 6.3 7.9 6.2 0.4 4.3 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX96759.1 - 0.0021 18.4 0.3 5.6 7.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX96759.1 - 0.0023 17.9 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KFX96759.1 - 0.0098 16.0 1.7 0.3 11.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 KFX96759.1 - 0.018 14.6 0.0 0.96 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFX96759.1 - 0.056 12.7 0.2 0.62 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KFX96759.1 - 0.058 12.7 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DEAD PF00270.29 KFX96759.1 - 0.18 11.5 0.1 20 4.9 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_15 PF13175.6 KFX96759.1 - 0.23 11.2 0.0 25 4.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFX96759.1 - 0.96 9.3 4.1 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 NACHT domain cobW PF02492.19 KFX96759.1 - 2.3 7.8 4.0 1.8 8.1 0.4 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Raffinose_syn PF05691.12 KFX96760.1 - 9.8e-50 169.1 2.0 8.2e-48 162.8 1.6 2.6 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_1b PF00579.25 KFX96761.1 - 1.8e-76 257.3 0.0 2.3e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KFX96761.1 - 8.3e-43 145.0 0.1 1.9e-42 143.8 0.1 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain LigD_N PF13298.6 KFX96762.1 - 3e-31 107.8 0.0 5.9e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) AA_permease PF00324.21 KFX96766.1 - 2.7e-144 481.3 35.1 3.3e-144 481.0 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX96766.1 - 7.4e-39 133.8 36.7 9.3e-39 133.4 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.13 KFX96766.1 - 0.16 11.7 3.3 0.39 10.4 3.3 1.6 1 0 0 1 1 1 0 WTF protein DUF4781 PF16013.5 KFX96766.1 - 0.34 9.7 1.2 0.66 8.7 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Pkinase PF00069.25 KFX96767.1 - 4.8e-67 226.1 0.0 6.7e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96767.1 - 9.6e-43 146.3 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96767.1 - 9.5e-10 38.2 0.0 3.4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFX96767.1 - 1.2e-06 27.7 0.2 1.2e-06 27.7 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFX96767.1 - 0.027 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX96767.1 - 0.16 11.9 7.6 1.2 9.0 0.1 3.6 2 2 2 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX96767.1 - 0.94 9.0 4.1 0.24 11.0 0.1 2.0 3 0 0 3 3 3 0 RIO1 family zf-C3HC4_3 PF13920.6 KFX96768.1 - 4.7e-06 26.4 7.8 4.7e-06 26.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX96768.1 - 1.7e-05 24.6 10.5 1.7e-05 24.6 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX96768.1 - 2e-05 24.8 11.7 2e-05 24.8 11.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX96768.1 - 3.1e-05 23.9 8.9 3.1e-05 23.9 8.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX96768.1 - 5e-05 23.1 11.3 5e-05 23.1 11.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX96768.1 - 5.2e-05 23.3 12.5 5.2e-05 23.3 12.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFX96768.1 - 0.00014 21.7 8.8 0.00014 21.7 8.8 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zinc-ribbons_6 PF07191.12 KFX96768.1 - 0.37 10.8 9.5 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 KFX96768.1 - 0.46 10.3 4.2 7.1 6.5 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KFX96768.1 - 0.63 10.1 5.4 0.83 9.7 0.1 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.6 KFX96768.1 - 2.5 8.1 15.8 0.1 12.5 7.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPF0547 PF10571.9 KFX96768.1 - 3.3 7.9 13.0 0.47 10.6 1.4 2.9 3 0 0 3 3 2 0 Uncharacterised protein family UPF0547 zf-RING_10 PF16685.5 KFX96768.1 - 5.1 7.3 12.6 1.3 9.2 7.5 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KFX96768.1 - 9.6 6.3 8.7 1.3 9.1 2.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger NatB_MDM20 PF09797.9 KFX96769.1 - 3.2e-58 197.5 0.0 6.6e-43 147.1 0.0 2.2 2 0 0 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFX96769.1 - 0.00054 20.4 5.8 0.19 12.2 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3797 PF12677.7 KFX96769.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) TPR_16 PF13432.6 KFX96769.1 - 7.2 7.4 7.1 0.82 10.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ilm1 PF10311.9 KFX96770.1 - 1.2e-45 155.2 0.4 1.3e-45 155.0 0.4 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 M20_dimer PF07687.14 KFX96771.1 - 2.1e-21 75.9 0.0 3.7e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFX96771.1 - 5.3e-16 58.9 0.0 8.5e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HAD PF12710.7 KFX96771.1 - 4.7e-05 23.9 0.0 0.02 15.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.17 KFX96771.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 HAD_2 PF13419.6 KFX96771.1 - 0.093 12.8 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SPOB_ab PF14682.6 KFX96771.1 - 0.2 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Prenyltrans PF00432.21 KFX96772.1 - 5.3e-35 118.8 4.3 3.2e-08 33.2 0.2 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFX96772.1 - 0.00029 20.0 0.0 0.012 14.7 0.0 2.7 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFX96772.1 - 0.081 12.0 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain ThiF PF00899.21 KFX96773.1 - 2.8e-58 197.2 0.0 4.6e-58 196.5 0.0 1.3 1 1 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFX96773.1 - 1.4e-10 41.7 0.1 7.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KFX96773.1 - 0.0056 16.8 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KFX96773.1 - 0.024 15.1 0.0 0.071 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFX96773.1 - 0.14 11.7 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KFX96773.1 - 0.22 10.6 1.2 0.35 9.9 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFX96773.1 - 0.34 10.1 1.1 0.49 9.6 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pam17 PF08566.10 KFX96774.1 - 1.7e-65 219.9 0.0 2.2e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Ribonuclease_3 PF00636.26 KFX96775.1 - 4.7e-41 139.7 0.0 1e-22 80.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFX96775.1 - 1.1e-26 93.5 0.0 1.1e-11 45.0 0.0 3.9 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KFX96775.1 - 2.9e-24 85.0 0.1 9.4e-24 83.4 0.1 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KFX96775.1 - 7.8e-16 58.3 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX96775.1 - 4.6e-15 55.9 0.1 1.5e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX96775.1 - 3.4e-14 53.2 0.0 6.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3638 PF12340.8 KFX96775.1 - 0.11 11.9 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Glyco_trans_2_3 PF13632.6 KFX96778.1 - 1.6e-18 67.4 0.6 1.6e-18 67.4 0.6 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF2768 PF10966.8 KFX96778.1 - 1.3 9.5 7.6 5.9 7.4 7.6 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) SesA PF17107.5 KFX96780.1 - 0.031 14.5 0.1 0.071 13.3 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases VIT PF08487.10 KFX96781.1 - 1.1e-31 109.3 1.1 2.4e-31 108.2 0.3 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KFX96781.1 - 5.4e-22 78.4 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX96781.1 - 3.6e-09 37.1 0.0 6.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFX96781.1 - 6e-09 36.5 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KFX96781.1 - 9.3e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KFX96781.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Frag1 PF10277.9 KFX96785.1 - 3.1e-41 141.3 9.5 6.9e-41 140.2 9.5 1.6 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.11 KFX96786.1 - 9.3e-14 51.3 0.1 1.2e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Pex14_N PF04695.13 KFX96786.1 - 0.046 14.4 0.2 0.055 14.1 0.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinesin PF00225.23 KFX96801.1 - 3.6e-31 108.3 0.0 5.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.15 KFX96801.1 - 2.9 8.0 9.2 5.7 7.1 2.0 2.8 2 0 0 2 2 2 0 Basic region leucine zipper ketoacyl-synt PF00109.26 KFX96803.1 - 9.9e-74 248.1 0.1 2.5e-72 243.5 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFX96803.1 - 1.9e-58 198.5 0.6 3.3e-58 197.7 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFX96803.1 - 6e-53 179.4 0.1 2e-52 177.7 0.1 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFX96803.1 - 1e-49 169.4 0.0 1.6e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFX96803.1 - 7.6e-36 122.7 0.0 2.8e-35 120.9 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFX96803.1 - 3.1e-20 72.7 0.0 1e-19 71.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFX96803.1 - 2.1e-14 53.9 0.0 8.5e-13 48.8 0.0 3.0 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KFX96803.1 - 9.5e-14 51.5 0.1 8.5e-13 48.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX96803.1 - 1.3e-13 52.1 0.0 1.5e-12 48.7 0.0 3.0 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 KFX96803.1 - 2.6e-10 40.3 0.0 9.8e-10 38.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX96803.1 - 3.7e-10 39.9 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96803.1 - 4e-10 40.3 0.0 2.1e-09 37.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFX96803.1 - 2.4e-09 36.9 0.4 1.6e-08 34.3 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 KFX96803.1 - 2.3e-07 31.3 0.0 6.9e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFX96803.1 - 8.9e-06 26.0 0.2 4.2e-05 23.8 0.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KFX96803.1 - 3e-05 23.5 0.0 8.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KFX96803.1 - 0.00011 21.7 0.1 0.00022 20.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KFX96803.1 - 0.029 14.1 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Polysacc_synt_2 PF02719.15 KFX96803.1 - 0.034 13.3 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 KFX96803.1 - 0.099 12.5 2.5 0.27 11.1 0.2 2.7 3 0 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.21 KFX96803.1 - 0.16 11.4 0.1 0.37 10.2 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Transferase PF02458.15 KFX96804.1 - 8e-32 110.4 0.0 1.2e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KFX96804.1 - 0.025 13.2 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Megourin PF17560.2 KFX96804.1 - 0.087 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Aphid Megourins DUF2264 PF10022.9 KFX96806.1 - 1.3e-127 425.8 0.1 1.6e-127 425.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.18 KFX96807.1 - 2.6e-15 56.2 0.1 5.1e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96807.1 - 9.6e-07 28.8 10.4 2e-06 27.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KFX96807.1 - 0.14 11.1 4.5 0.23 10.4 4.5 1.3 1 0 0 1 1 1 0 Clusterin Glyco_hydro_88 PF07470.13 KFX96808.1 - 1.7e-10 40.5 0.0 3.5e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Gemini_AL1_M PF08283.11 KFX96808.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain MFS_1 PF07690.16 KFX96809.1 - 3.2e-27 95.4 18.8 3.8e-26 91.9 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 KFX96809.1 - 0.0039 17.7 0.0 0.0093 16.5 0.0 1.6 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Phage_holin_3_6 PF07332.11 KFX96809.1 - 0.23 11.5 2.9 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Grg1 PF11034.8 KFX96810.1 - 9e-33 112.3 11.9 1e-32 112.2 11.9 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 HATPase_c PF02518.26 KFX96811.1 - 4.2e-20 72.3 0.1 8.6e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFX96811.1 - 1.3e-16 60.7 0.1 3.4e-12 46.5 0.0 3.7 4 0 0 4 4 4 2 Response regulator receiver domain HisKA PF00512.25 KFX96811.1 - 2e-12 46.9 0.0 5.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KFX96811.1 - 0.0016 18.8 0.0 0.0054 17.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain F-box-like PF12937.7 KFX96812.1 - 6.7e-05 22.7 0.9 0.00018 21.3 0.1 2.2 2 1 0 2 2 2 1 F-box-like FAD_binding_4 PF01565.23 KFX96813.1 - 8.1e-21 74.2 2.3 1.7e-20 73.2 2.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX96813.1 - 9.6e-07 28.8 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3237 PF11578.8 KFX96814.1 - 1.3e-06 28.3 0.1 1.7e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OPT PF03169.15 KFX96815.1 - 3.2e-125 419.2 43.4 3.7e-125 418.9 43.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.6 KFX96815.1 - 1.2 9.6 3.4 0.76 10.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3093 PF11292.8 KFX96815.1 - 9 6.6 7.7 22 5.3 5.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) Pectate_lyase PF03211.13 KFX96816.1 - 4.7e-77 258.1 7.8 5.8e-77 257.8 7.8 1.1 1 0 0 1 1 1 1 Pectate lyase Cnn_1N PF07989.11 KFX96819.1 - 0.07 13.3 6.6 0.044 13.9 1.2 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Glyco_hydro_16 PF00722.21 KFX96820.1 - 1.5e-17 63.6 0.1 2.6e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nucleoporin_FG PF13634.6 KFX96825.1 - 2.9e-14 53.7 101.8 7.5e-06 26.7 27.8 5.1 1 1 4 5 5 5 4 Nucleoporin FG repeat region F-box-like PF12937.7 KFX96828.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like RPN7 PF10602.9 KFX96828.1 - 0.0002 21.1 0.1 0.00039 20.2 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 KFX96828.1 - 0.032 13.8 0.0 0.092 12.3 0.0 1.7 1 1 0 1 1 1 0 ComR tetratricopeptide TPR_19 PF14559.6 KFX96828.1 - 0.079 13.5 1.4 0.2 12.2 1.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 KFX96829.1 - 1.3e-45 155.8 0.0 4.9e-45 153.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96829.1 - 1.7e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFX96829.1 - 0.0057 16.3 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFX96829.1 - 0.088 12.7 0.0 10 6.0 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cir_N PF10197.9 KFX96830.1 - 2e-05 24.7 1.5 2e-05 24.7 1.5 4.6 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.29 KFX96831.1 - 1.1e-52 177.9 0.0 2.5e-38 131.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX96831.1 - 2.6e-10 40.9 0.0 0.00073 20.0 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFX96831.1 - 2.7e-10 40.7 0.1 0.00064 20.0 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 KFX96831.1 - 6.7e-10 38.6 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 KFX96831.1 - 1.4e-09 37.6 0.3 6e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 KFX96831.1 - 1.9e-07 30.6 0.0 0.0061 15.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KFX96831.1 - 2e-07 30.9 0.1 0.014 15.2 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFX96831.1 - 2e-07 31.1 0.0 0.0026 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KFX96831.1 - 2.4e-07 31.1 0.0 0.023 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 KFX96831.1 - 7.2e-07 29.5 0.2 0.00071 19.7 0.1 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KFX96831.1 - 1.2e-06 28.4 0.0 0.0078 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KFX96831.1 - 1.4e-06 28.4 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFX96831.1 - 3.4e-06 27.6 0.0 0.025 15.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KFX96831.1 - 6.4e-06 26.4 0.0 0.043 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KFX96831.1 - 7.1e-06 26.0 0.3 0.011 15.6 0.0 3.3 4 0 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.26 KFX96831.1 - 9.4e-06 25.4 0.0 0.073 12.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFX96831.1 - 1e-05 25.0 0.1 0.017 14.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFX96831.1 - 1.9e-05 24.3 0.2 0.035 13.6 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFX96831.1 - 2.9e-05 23.9 0.2 0.11 12.3 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KFX96831.1 - 4.3e-05 23.5 0.6 1.7 8.5 0.0 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFX96831.1 - 4.5e-05 22.8 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TsaE PF02367.17 KFX96831.1 - 5.2e-05 23.3 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KFX96831.1 - 0.00015 22.3 0.1 0.36 11.3 0.1 2.6 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 KFX96831.1 - 0.00039 19.8 0.4 0.031 13.6 0.3 2.4 2 0 0 2 2 2 1 KaiC CDC48_N PF02359.18 KFX96831.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain PhoH PF02562.16 KFX96831.1 - 0.00098 18.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KFX96831.1 - 0.0023 18.0 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFX96831.1 - 0.0023 17.7 0.0 0.9 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFX96831.1 - 0.0027 17.9 0.0 0.99 9.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KFX96831.1 - 0.0039 16.6 0.2 3.2 7.1 0.1 3.7 3 1 0 3 3 3 1 Bacterial TniB protein AAA_25 PF13481.6 KFX96831.1 - 0.004 16.7 1.1 2.3 7.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.6 KFX96831.1 - 0.008 16.0 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFX96831.1 - 0.011 16.1 0.0 1.1 9.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF2075 PF09848.9 KFX96831.1 - 0.011 15.0 0.2 2.2 7.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 KFX96831.1 - 0.011 16.1 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFX96831.1 - 0.018 14.8 0.2 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KFX96831.1 - 0.019 14.1 0.0 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KFX96831.1 - 0.028 13.7 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KFX96831.1 - 0.043 13.4 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.11 KFX96831.1 - 0.055 13.3 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KFX96831.1 - 0.057 13.1 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase CPT PF07931.12 KFX96831.1 - 0.1 12.5 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 KFX96831.1 - 0.11 11.6 0.0 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 KFX96831.1 - 0.11 11.7 0.0 6.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KFX96831.1 - 0.15 11.9 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KFX96831.1 - 0.16 12.1 0.0 26 4.9 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Vps4_C PF09336.10 KFX96831.1 - 0.17 11.9 0.1 0.63 10.1 0.0 2.0 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain DAP3 PF10236.9 KFX96831.1 - 0.17 11.0 0.0 10 5.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 IPT PF01745.16 KFX96831.1 - 0.18 11.2 0.1 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase RasGEF PF00617.19 KFX96832.1 - 2.6e-39 135.2 0.3 4.1e-39 134.6 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFX96832.1 - 2.9e-07 30.7 0.2 1.4e-06 28.5 0.2 2.2 1 1 0 1 1 1 1 RasGEF N-terminal motif Par3_HAL_N_term PF12053.8 KFX96838.1 - 0.038 14.2 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins ANAPC4_WD40 PF12894.7 KFX96838.1 - 0.21 11.9 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 KFX96838.1 - 0.52 8.8 8.6 0.62 8.6 8.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AF-4 PF05110.13 KFX96838.1 - 0.97 7.4 3.8 1.2 7.2 3.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HAD PF12710.7 KFX96847.1 - 2.8e-22 80.0 0.0 4.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFX96847.1 - 0.00023 20.7 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KFX96847.1 - 0.004 17.5 0.1 0.26 11.5 0.0 2.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFX96847.1 - 0.034 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.11 KFX96848.1 - 2.7e-82 275.4 2.5 4.1e-82 274.8 2.5 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 KFX96848.1 - 0.14 11.9 1.2 0.26 11.1 1.2 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein PAS_9 PF13426.7 KFX96848.1 - 0.19 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain Pex14_N PF04695.13 KFX96848.1 - 9.5 6.9 11.4 11 6.6 6.5 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 KFX96850.1 - 2.8e-60 203.9 0.0 5.6e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96850.1 - 2.3e-36 125.4 0.0 4.1e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFX96850.1 - 4.6e-23 81.1 18.7 2.7e-11 43.4 3.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KFX96850.1 - 2.4e-19 69.0 29.1 7.2e-12 45.0 9.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFX96850.1 - 1.9e-14 54.0 2.3 5.8e-14 52.5 2.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KFX96850.1 - 7.6e-05 23.0 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KFX96850.1 - 0.0046 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX96850.1 - 0.065 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 KFX96850.1 - 5.1 7.0 20.8 3 7.8 5.6 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Acyl-CoA_dh_1 PF00441.24 KFX96851.1 - 1.4e-40 138.9 3.3 2.6e-40 138.1 3.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX96851.1 - 3e-29 102.0 0.4 6.1e-29 101.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX96851.1 - 8.6e-24 83.6 0.1 2e-23 82.4 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX96851.1 - 4.4e-17 62.6 0.4 4.4e-17 62.6 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFX96851.1 - 0.032 13.9 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.25 KFX96852.1 - 1.2e-28 99.0 1.4 1.6e-28 98.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.16 KFX96853.1 - 3.8e-132 440.5 8.2 4.6e-132 440.2 8.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 KFX96854.1 - 0 1277.3 18.4 0 1277.0 18.4 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Herpes_HEPA PF03324.14 KFX96854.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein DAHP_synth_2 PF01474.16 KFX96861.1 - 5.8e-199 661.1 0.0 6.6e-199 660.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HIG_1_N PF04588.13 KFX96863.1 - 2.5e-23 82.0 0.1 3.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 KFX96863.1 - 0.093 12.8 8.9 0.075 13.1 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Asp4 PF16996.5 KFX96863.1 - 0.24 11.2 1.9 0.58 10.0 1.9 1.7 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 Mem_trans PF03547.18 KFX96863.1 - 0.85 7.9 2.3 1.1 7.6 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Presenilin PF01080.17 KFX96863.1 - 9.6 4.8 9.1 13 4.4 9.1 1.1 1 0 0 1 1 1 0 Presenilin PALP PF00291.25 KFX96864.1 - 2.5e-79 266.8 0.5 3.1e-79 266.5 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KFX96864.1 - 8.3e-42 140.9 0.0 4.8e-21 74.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Peptidase_C12 PF01088.21 KFX96865.1 - 8.1e-47 159.7 0.0 9.6e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Vfa1 PF08432.10 KFX96867.1 - 1 9.6 6.2 2 8.7 6.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 KFX96867.1 - 2.4 6.6 7.8 3.7 6.0 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AA_permease PF00324.21 KFX96868.1 - 1.5e-139 465.7 49.1 1.9e-139 465.4 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX96868.1 - 7e-33 114.1 54.0 8.7e-33 113.8 54.0 1.1 1 0 0 1 1 1 1 Amino acid permease EMC3_TMCO1 PF01956.16 KFX96882.1 - 1.6e-28 99.6 0.4 1.8e-28 99.4 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PS_pyruv_trans PF04230.13 KFX96882.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase SPC25 PF06703.11 KFX96883.1 - 1.8e-34 118.8 0.0 2.1e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_1 PF00076.22 KFX96888.1 - 1.3e-08 34.5 0.6 0.0036 17.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ino80_Iec3 PF14612.6 KFX96889.1 - 7.8e-71 239.5 0.4 1.1e-70 239.0 0.4 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 KFX96890.1 - 1.4e-72 244.7 0.0 1.8e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF737 PF05300.11 KFX96891.1 - 8.9 6.6 10.2 2 8.7 6.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) GFA PF04828.14 KFX96893.1 - 4.8e-08 33.2 0.2 7.6e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Neisseria_TspB PF05616.13 KFX96893.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Patatin PF01734.22 KFX96894.1 - 2.2e-20 73.7 0.0 4.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KFX96894.1 - 9.4e-13 47.9 0.0 2.1e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 KFX96894.1 - 1.1e-10 41.0 0.1 4.4e-10 39.1 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX96894.1 - 6.4e-07 29.6 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFX96894.1 - 2e-05 25.0 0.3 0.00017 22.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_8 PF13181.6 KFX96894.1 - 0.0024 18.0 0.1 0.0091 16.1 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFX96894.1 - 0.013 15.5 0.2 0.078 13.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_7 PF12775.7 KFX96894.1 - 0.043 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_1 PF00515.28 KFX96894.1 - 0.05 13.4 0.3 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX96894.1 - 0.15 12.2 2.0 0.39 10.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEP PF00610.21 KFX96894.1 - 0.16 12.0 0.3 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) p450 PF00067.22 KFX96897.1 - 1.6e-59 201.9 0.0 1.9e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.23 KFX96899.1 - 7.1e-27 94.2 14.4 8.3e-27 94.0 14.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain MTABC_N PF16185.5 KFX96899.1 - 0.083 12.4 4.6 0.12 11.8 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region MpPF26 PF07666.11 KFX96899.1 - 0.33 11.1 7.5 0.56 10.3 4.8 2.4 2 1 0 2 2 2 0 M penetrans paralogue family 26 PNGaseA PF12222.8 KFX96901.1 - 2.4e-160 534.1 0.1 3.2e-160 533.7 0.1 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A ADH_N PF08240.12 KFX96902.1 - 3.8e-22 78.2 0.1 9.6e-22 76.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX96902.1 - 1.8e-16 60.3 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX96902.1 - 0.0036 16.7 0.1 0.0063 15.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFX96902.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Cwf_Cwc_15 PF04889.12 KFX96904.1 - 1e-48 166.3 12.6 1.1e-48 166.2 12.6 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Casc1_N PF15927.5 KFX96904.1 - 1.1 8.9 14.6 1.5 8.5 14.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Pet100 PF09803.9 KFX96904.1 - 2.1 9.0 5.7 4.3 7.9 5.7 1.5 1 0 0 1 1 1 0 Pet100 Cupin_2 PF07883.11 KFX96905.1 - 1.1e-06 28.3 0.1 1.5e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX96905.1 - 3.6e-05 23.4 0.2 4.5e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFX96905.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_3 PF01494.19 KFX96906.1 - 4.1e-29 101.9 0.1 4e-28 98.7 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFX96906.1 - 2.2e-08 33.8 0.7 0.00033 20.1 0.1 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX96906.1 - 2.6e-07 30.2 0.2 2.7e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX96906.1 - 2.3e-05 24.5 0.2 9.2e-05 22.6 0.2 2.1 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX96906.1 - 0.00029 20.2 0.4 0.029 13.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX96906.1 - 0.00041 19.2 0.3 0.036 12.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KFX96906.1 - 0.00047 19.9 1.4 0.005 16.5 1.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX96906.1 - 0.00052 19.2 1.1 0.23 10.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KFX96906.1 - 0.00068 18.9 0.2 0.0033 16.7 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KFX96906.1 - 0.0038 17.8 1.4 0.036 14.6 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFX96906.1 - 0.015 15.6 0.2 0.12 12.7 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 KFX96906.1 - 0.019 14.1 1.0 0.03 13.4 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFX96906.1 - 0.023 13.5 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KFX96906.1 - 0.026 14.5 1.1 22 5.0 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFX96906.1 - 0.045 13.1 0.2 0.18 11.1 0.2 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 KFX96906.1 - 0.066 12.6 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 KFX96906.1 - 0.12 12.0 0.3 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KFX96907.1 - 8.6e-10 38.1 0.1 1.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96907.1 - 1.6e-09 37.7 8.5 3.3e-09 36.7 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 KFX96908.1 - 1e-21 78.4 0.0 2e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX96908.1 - 3.1e-13 49.8 0.0 5.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX96908.1 - 8.3e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KFX96908.1 - 1.9e-05 25.1 0.0 3.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX96908.1 - 8.9e-05 22.6 0.2 0.0002 21.5 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DUF2855 PF11017.8 KFX96908.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) RmlD_sub_bind PF04321.17 KFX96908.1 - 0.0053 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 KFX96908.1 - 0.062 12.6 0.5 0.26 10.6 0.5 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KFX96908.1 - 0.085 12.4 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 KFX96908.1 - 0.088 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Aldedh PF00171.22 KFX96909.1 - 2e-80 270.5 0.0 2.4e-80 270.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNA_pol_Rpb2_1 PF04563.15 KFX96909.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit DUF1542 PF07564.11 KFX96909.1 - 0.43 10.7 1.8 0.77 9.9 0.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Fungal_trans_2 PF11951.8 KFX96910.1 - 3.6e-06 26.0 1.5 8.9e-05 21.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 KFX96911.1 - 3.4e-22 78.8 0.0 2.1e-17 63.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96911.1 - 1e-10 41.6 0.0 1.6e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96911.1 - 1.6e-08 34.7 0.4 3.9e-08 33.4 0.1 1.7 2 0 0 2 2 2 1 KR domain MFS_1 PF07690.16 KFX96912.1 - 1.1e-08 34.5 41.0 5.4e-05 22.3 5.7 4.0 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX96912.1 - 0.0015 17.0 8.1 0.0015 17.0 8.1 2.7 3 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX96912.1 - 1.8 6.8 18.9 0.17 10.1 3.7 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4538 PF15061.6 KFX96912.1 - 7.3 6.4 6.2 31 4.4 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Methyltransf_2 PF00891.18 KFX96913.1 - 1.8e-17 63.4 0.0 2.9e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KFX96913.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MarR family FeoC PF09012.10 KFX96913.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator DsbD PF02683.15 KFX96913.1 - 0.24 11.3 0.0 0.55 10.1 0.0 1.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Rotamase PF00639.21 KFX96914.1 - 5.1e-13 49.8 0.0 7.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFX96914.1 - 7.7e-13 49.0 0.0 1.4e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFX96914.1 - 0.002 19.0 4.1 0.0028 18.5 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain WW PF00397.26 KFX96921.1 - 9.2e-11 41.6 0.2 2.1e-10 40.5 0.2 1.7 1 0 0 1 1 1 1 WW domain Ank_5 PF13857.6 KFX96922.1 - 8.1e-19 67.5 0.2 9.3e-13 48.1 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KFX96922.1 - 3.8e-16 59.2 0.0 9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KFX96922.1 - 3.7e-15 56.3 0.0 7.2e-05 23.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX96922.1 - 1.2e-09 38.5 0.2 0.0027 18.3 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX96922.1 - 5.2e-09 35.6 0.3 0.12 13.0 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFX96922.1 - 6.3e-07 29.6 0.2 0.59 10.7 0.4 5.0 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.24 KFX96922.1 - 0.049 13.6 0.2 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 PX domain PGM_PMM_I PF02878.16 KFX96923.1 - 2.1e-31 108.5 0.3 4e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNase_T PF00929.24 KFX96923.1 - 1.1e-27 97.7 0.1 2.6e-27 96.4 0.1 1.7 1 0 0 1 1 1 1 Exonuclease PGM_PMM_III PF02880.16 KFX96923.1 - 1.2e-24 86.7 0.0 2.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFX96923.1 - 1.1e-16 61.3 0.1 3.1e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFX96923.1 - 9.5e-09 35.3 0.0 2.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KFX96924.1 - 3.2e-09 37.7 0.0 7.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX96924.1 - 4.3e-05 23.5 0.0 9.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 KFX96924.1 - 0.03 14.4 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system Dus PF01207.17 KFX96925.1 - 1e-40 139.8 0.0 6.5e-30 104.3 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KFX96925.1 - 0.0042 16.9 6.8 0.083 12.7 0.3 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Kelch_1 PF01344.25 KFX96926.1 - 1.1e-41 140.2 16.3 1.3e-07 31.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFX96926.1 - 1.4e-36 123.9 13.5 4.5e-06 26.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFX96926.1 - 8.9e-34 115.1 19.0 2.3e-07 30.9 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFX96926.1 - 2.1e-33 114.1 18.5 2.9e-07 30.4 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFX96926.1 - 4.7e-31 105.6 13.3 2.8e-06 27.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFX96926.1 - 2.5e-30 103.7 16.7 3.3e-06 27.2 0.1 6.4 4 2 2 6 6 6 6 Kelch motif HIG_1_N PF04588.13 KFX96927.1 - 6.1e-06 26.4 1.3 6.1e-06 26.4 1.3 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region zf-C2H2_aberr PF17017.5 KFX96928.1 - 0.00034 20.8 5.1 0.022 14.9 0.2 2.6 3 0 0 3 3 3 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFX96928.1 - 0.00084 19.7 8.8 0.0076 16.6 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFX96928.1 - 0.0016 18.8 17.0 0.06 13.8 1.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX96928.1 - 0.0031 18.2 16.9 0.018 15.8 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX96928.1 - 4.1 7.8 8.8 3.2 8.2 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ABC_tran_CTD PF16326.5 KFX96931.1 - 0.036 14.3 0.2 0.12 12.6 0.2 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain FlxA PF14282.6 KFX96931.1 - 0.046 13.7 0.3 0.13 12.3 0.3 1.7 1 0 0 1 1 1 0 FlxA-like protein ADIP PF11559.8 KFX96931.1 - 0.58 10.2 3.5 0.99 9.5 3.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Glutaredoxin PF00462.24 KFX96933.1 - 4.9e-12 45.9 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin CDH-cyt PF16010.5 KFX96940.1 - 3.9e-12 46.2 0.2 8.9e-12 45.1 0.2 1.5 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KFX96940.1 - 5.8e-06 26.0 2.7 1.1e-05 25.1 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KFX96940.1 - 3.9e-05 23.8 8.3 3.9e-05 23.8 8.3 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KFX96940.1 - 5.2e-05 23.4 0.1 9.5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 DOMON domain Pkinase PF00069.25 KFX96941.1 - 2.7e-67 226.9 0.0 3.4e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96941.1 - 2.3e-30 105.7 0.0 3.2e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96941.1 - 0.00013 21.4 0.0 0.0003 20.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX96941.1 - 0.0015 17.6 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 KFX96941.1 - 0.023 15.4 0.1 0.062 14.0 0.1 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 KFX96941.1 - 0.034 12.9 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DSS1_SEM1 PF05160.13 KFX96942.1 - 1.3 9.2 3.9 0.6 10.2 1.8 1.5 2 0 0 2 2 2 0 DSS1/SEM1 family CRF1 PF10380.9 KFX96943.1 - 0.0029 17.9 0.8 0.0092 16.3 0.0 2.3 2 0 0 2 2 2 1 Transcription factor CRF1 Myb_DNA-bind_6 PF13921.6 KFX96945.1 - 1.6e-14 53.8 1.3 1.6e-14 53.8 1.3 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX96945.1 - 7.1e-06 26.1 1.1 1.4e-05 25.2 1.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dabb PF07876.12 KFX96954.1 - 9.7e-21 74.2 0.1 1.1e-20 74.0 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Laminin_EGF PF00053.24 KFX96955.1 - 0.1 12.7 6.2 0.22 11.7 6.2 1.6 1 0 0 1 1 1 0 Laminin EGF domain CFEM PF05730.11 KFX96955.1 - 0.34 11.0 10.5 0.58 10.3 10.5 1.3 1 0 0 1 1 1 0 CFEM domain RAP1 PF07218.11 KFX96955.1 - 5.9 5.0 15.3 6 5.0 15.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPX PF03105.19 KFX96955.1 - 7 6.5 8.5 7.4 6.4 8.5 1.1 1 0 0 1 1 1 0 SPX domain HATPase_c_3 PF13589.6 KFX96956.1 - 5.7e-16 58.6 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KFX96956.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KFX96956.1 - 0.0033 17.9 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FNIP_N PF14636.6 KFX96974.1 - 6.4e-05 24.0 0.0 6.4e-05 24.0 0.0 3.5 5 0 0 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 KFX96974.1 - 0.16 11.9 0.1 1 9.3 0.0 2.1 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Complex1_LYR_2 PF13233.6 KFX96979.1 - 5e-05 24.0 0.7 8.2e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFX96979.1 - 0.0043 17.1 0.1 0.011 15.8 0.1 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.8 KFX96979.1 - 0.026 14.0 0.5 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 R.HinP1I restriction endonuclease TMIE PF16038.5 KFX96979.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 1 1 2 2 2 0 TMIE protein RNA_pol_L_2 PF13656.6 KFX96980.1 - 9.4e-34 115.0 0.0 1.5e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFX96980.1 - 4.9e-12 45.1 0.0 7.6e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain G10 PF01125.17 KFX96989.1 - 1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.3 1 1 0 1 1 1 1 G10 protein MARVEL PF01284.23 KFX96991.1 - 3.4e-15 56.3 13.1 3.9e-15 56.1 13.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain Mpv17_PMP22 PF04117.12 KFX96993.1 - 9e-16 57.9 0.2 9e-16 57.9 0.2 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family NQR2_RnfD_RnfE PF03116.15 KFX96993.1 - 0.0092 15.4 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family Glyco_transf_22 PF03901.17 KFX96994.1 - 5e-46 157.8 3.3 5.7e-46 157.6 3.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_17 PF00332.18 KFX96996.1 - 1.3e-07 31.6 0.4 2.3e-07 30.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Abhydrolase_6 PF12697.7 KFX96997.1 - 1.1e-13 52.3 0.0 1.4e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX96997.1 - 2.8e-05 23.5 0.0 4.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX96997.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 KFX96998.1 - 7.4e-63 212.4 0.0 9e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96998.1 - 7.6e-36 123.7 0.0 1.4e-35 122.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96998.1 - 6.8e-07 28.9 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX96998.1 - 0.00081 18.3 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KFX96998.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.29 KFX96999.1 - 2.1e-40 138.3 0.0 1e-39 136.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX96999.1 - 8.3e-30 103.4 0.1 3.6e-29 101.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX96999.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFX96999.1 - 0.0039 16.0 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HRI1 PF16815.5 KFX97001.1 - 2.9e-62 210.4 0.2 3.2e-62 210.2 0.2 1.0 1 0 0 1 1 1 1 Protein HRI1 SRF-TF PF00319.18 KFX97004.1 - 8.3e-10 38.0 0.0 1.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA PF00004.29 KFX97005.1 - 2.1e-16 60.5 0.0 3.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX97005.1 - 9.1e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFX97005.1 - 0.0002 21.8 0.0 0.00036 21.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX97005.1 - 0.00035 20.9 0.8 0.006 16.9 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KFX97005.1 - 0.00076 19.3 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX97005.1 - 0.0035 17.9 0.0 0.0074 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFX97005.1 - 0.0035 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 KFX97005.1 - 0.0054 16.6 1.1 0.33 10.8 0.1 2.6 1 1 1 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.21 KFX97005.1 - 0.015 14.7 0.3 0.032 13.6 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFX97005.1 - 0.017 15.1 0.1 0.39 10.6 0.0 2.5 1 1 1 2 2 2 0 NACHT domain Zot PF05707.12 KFX97005.1 - 0.03 14.0 0.0 0.26 10.9 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_14 PF13173.6 KFX97005.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX97005.1 - 0.03 14.7 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KFX97005.1 - 0.037 14.4 0.0 0.095 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain HET-s_218-289 PF11558.8 KFX97005.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Het-s 218-289 AAA_33 PF13671.6 KFX97005.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX97005.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 KFX97008.1 - 2.2e-11 43.7 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97008.1 - 6.7e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.29 KFX97009.1 - 4.9e-18 65.8 0.0 1.2e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX97009.1 - 6.9e-05 23.3 0.4 0.00038 20.9 0.0 2.4 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX97009.1 - 0.00011 22.5 0.1 0.0014 18.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX97009.1 - 0.00017 21.6 0.0 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KFX97009.1 - 0.0021 18.3 0.0 0.96 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFX97009.1 - 0.0027 17.5 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KFX97009.1 - 0.0047 17.5 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KFX97009.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX97009.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFX97009.1 - 0.05 13.0 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 KFX97009.1 - 0.064 13.1 0.1 3.2 7.5 0.0 2.4 1 1 1 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 KFX97009.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KFX97009.1 - 0.085 12.9 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX97009.1 - 0.1 12.5 0.1 1.2 9.0 0.1 2.3 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KFX97009.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX97009.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFX97009.1 - 0.17 12.3 0.0 0.56 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain CENP-B_N PF04218.13 KFX97012.1 - 5e-07 29.3 0.1 1.4e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KFX97012.1 - 1.2e-05 24.9 0.4 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 KFX97012.1 - 0.0034 17.4 0.3 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KFX97012.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.6 KFX97012.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 KFX97012.1 - 0.023 14.6 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_37 PF13744.6 KFX97012.1 - 0.04 13.9 0.3 0.8 9.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.6 KFX97012.1 - 0.043 13.4 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KFX97012.1 - 0.05 13.5 0.1 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 MarR family Acetyltransf_10 PF13673.7 KFX97014.1 - 1.1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97014.1 - 2.8e-09 37.2 0.0 4.3e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX97014.1 - 2.3e-08 34.3 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX97014.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX97014.1 - 0.04 14.0 0.0 0.068 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Myb_DNA-bind_6 PF13921.6 KFX97016.1 - 0.0066 16.7 0.3 0.061 13.6 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Abhydrolase_3 PF07859.13 KFX97017.1 - 1.9e-49 168.4 0.0 2.8e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX97017.1 - 2.8e-17 62.8 0.0 6.6e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KFX97017.1 - 0.00016 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Epimerase PF01370.21 KFX97017.1 - 0.0014 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX97017.1 - 0.029 13.5 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Lipase_3 PF01764.25 KFX97017.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.16 KFX97020.1 - 3.7e-31 108.3 37.2 3.7e-31 108.3 37.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily BNIP3 PF06553.12 KFX97020.1 - 0.027 14.2 0.8 0.046 13.4 0.8 1.2 1 0 0 1 1 1 0 BNIP3 SBP_bac_11 PF13531.6 KFX97020.1 - 0.078 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DJ-1_PfpI PF01965.24 KFX97021.1 - 9.1e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family EHN PF06441.12 KFX97022.1 - 1.5e-27 96.1 0.2 2.4e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFX97022.1 - 9.3e-12 45.1 0.1 1.8e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX97022.1 - 0.0044 17.7 0.8 0.009 16.6 0.6 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.18 KFX97023.1 - 0.013 15.6 9.9 0.024 14.8 9.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.23 KFX97024.1 - 1.5e-75 254.1 0.1 3.4e-75 253.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFX97024.1 - 1.6e-41 140.9 4.6 4e-41 139.6 2.3 2.6 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KFX97024.1 - 2.7e-38 131.1 0.9 2.7e-38 131.1 0.9 4.9 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 KFX97024.1 - 6.6e-19 68.3 0.3 1e-17 64.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97024.1 - 1.6e-11 44.5 0.0 9.7e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KFX97024.1 - 1.7e-05 24.9 0.0 0.0032 17.6 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD PF00270.29 KFX97024.1 - 9.6e-05 22.2 0.0 0.0003 20.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFX97024.1 - 0.00021 21.1 0.0 0.00066 19.4 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KFX97024.1 - 0.0012 18.1 0.7 0.0034 16.6 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 KFX97024.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 KFX97024.1 - 0.11 12.6 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFX97024.1 - 0.17 12.2 0.5 1.7 8.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.6 KFX97025.1 - 2.5e-05 24.2 0.4 4.7e-05 23.3 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) ECR1_N PF14382.6 KFX97026.1 - 4e-16 58.5 0.7 1.2e-15 57.0 0.7 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KFX97026.1 - 3e-06 27.5 0.6 6.2e-06 26.5 0.6 1.5 1 0 0 1 1 1 1 KH domain DUF4536 PF15055.6 KFX97027.1 - 0.00024 21.3 5.5 0.0018 18.4 5.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.21 KFX97028.1 - 1.7e-63 214.5 0.0 2.1e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFX97028.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain LRIF1 PF15741.5 KFX97028.1 - 0.19 10.2 0.2 0.29 9.6 0.2 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Uds1 PF15456.6 KFX97029.1 - 4.8e-33 114.1 4.2 4.8e-33 114.1 4.2 1.9 2 0 0 2 2 2 1 Up-regulated During Septation DUF812 PF05667.11 KFX97029.1 - 0.0017 17.3 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Bap31_Bap29_C PF18035.1 KFX97029.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Stathmin PF00836.19 KFX97029.1 - 0.039 13.9 0.5 0.2 11.6 0.5 2.2 1 0 0 1 1 1 0 Stathmin family Wbp11 PF09429.10 KFX97029.1 - 0.087 13.2 0.3 0.24 11.8 0.3 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 Peptidase_M1 PF01433.20 KFX97031.1 - 2.3e-43 148.3 0.9 3.1e-43 147.9 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFX97031.1 - 3.5e-35 120.5 0.0 7.3e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFX97031.1 - 2e-29 103.1 0.0 3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain COX5A PF02284.16 KFX97031.1 - 0.22 11.5 0.2 0.48 10.5 0.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Peptidase_M61 PF05299.12 KFX97031.1 - 0.24 11.8 2.4 3.7 8.0 2.4 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M20 PF01546.28 KFX97032.1 - 3.9e-33 114.9 0.0 5.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX97032.1 - 3.5e-14 52.6 0.0 6.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFX97032.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.6 KFX97033.1 - 8e-12 45.2 0.1 5.9e-05 23.2 0.0 4.0 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 KFX97033.1 - 0.0021 18.2 0.7 7.1 7.1 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KFX97033.1 - 0.013 15.6 0.0 4.6 7.4 0.0 3.4 2 1 1 3 3 3 0 Pentatricopeptide repeat domain KH_1 PF00013.29 KFX97033.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 KH domain RNA_pol_Rpb1_1 PF04997.12 KFX97034.1 - 1.3e-85 287.5 0.1 2.1e-85 286.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KFX97034.1 - 2.3e-79 266.6 0.1 4e-79 265.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFX97034.1 - 7.8e-71 237.7 0.0 1.7e-70 236.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFX97034.1 - 2e-38 131.8 0.0 4.8e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFX97034.1 - 4.7e-29 100.5 0.2 1.6e-28 98.8 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phlebovirus_NSM PF07246.11 KFX97035.1 - 0.047 13.1 0.5 0.053 12.9 0.5 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Pannexin_like PF12534.8 KFX97035.1 - 1.3 8.1 2.2 1.4 7.9 2.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Rx_N PF18052.1 KFX97036.1 - 0.034 14.4 1.7 0.061 13.6 1.7 1.4 1 0 0 1 1 1 0 Rx N-terminal domain AA_permease_2 PF13520.6 KFX97037.1 - 2.9e-42 145.0 51.1 3.6e-42 144.7 51.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX97037.1 - 2.6e-11 42.8 42.4 3.6e-11 42.3 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_7 PF13508.7 KFX97038.1 - 6.7e-05 23.2 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX97038.1 - 8.6e-05 22.6 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX97038.1 - 0.0079 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97038.1 - 0.075 13.3 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family AA_permease_2 PF13520.6 KFX97040.1 - 5.5e-62 210.0 45.3 6.8e-62 209.7 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX97040.1 - 6.7e-32 110.7 35.8 9.2e-32 110.3 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KFX97041.1 - 5.1e-09 35.5 24.7 5.1e-09 35.5 24.7 3.7 2 2 1 3 3 3 1 Major Facilitator Superfamily SecG PF03840.14 KFX97041.1 - 4.4 7.4 8.1 35 4.6 0.2 3.8 3 0 0 3 3 3 0 Preprotein translocase SecG subunit Pec_lyase_C PF00544.19 KFX97042.1 - 0.025 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Pectate lyase FAD_binding_3 PF01494.19 KFX97043.1 - 7.9e-16 58.2 0.5 9e-15 54.8 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX97043.1 - 1e-07 31.5 0.1 0.00058 19.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX97043.1 - 7e-05 23.3 0.1 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX97043.1 - 7.1e-05 22.6 0.5 0.0012 18.5 0.3 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX97043.1 - 0.013 15.8 0.2 0.029 14.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KFX97043.1 - 0.17 11.5 0.2 0.36 10.4 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 KFX97044.1 - 3.9e-17 62.1 0.1 6.1e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX97044.1 - 1.3e-08 34.9 10.5 2.3e-08 34.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 KFX97045.1 - 5.2e-60 203.2 0.5 1e-59 202.3 0.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX97045.1 - 1.8e-34 119.2 0.0 2.4e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 KFX97046.1 - 2.4e-128 428.8 35.3 2.8e-128 428.6 35.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97046.1 - 2.9e-19 69.2 51.8 1.1e-15 57.4 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX97046.1 - 0.00064 18.4 0.9 0.00064 18.4 0.9 2.7 3 1 0 3 3 3 1 MFS/sugar transport protein Erg28 PF03694.13 KFX97053.1 - 1.3e-24 86.7 0.1 1.5e-24 86.5 0.1 1.0 1 0 0 1 1 1 1 Erg28 like protein WSC PF01822.19 KFX97054.1 - 1.1e-07 31.9 4.9 1.1e-07 31.9 4.9 2.2 2 1 0 2 2 2 1 WSC domain Rpn3_C PF08375.11 KFX97056.1 - 1.2e-25 89.7 1.7 3.3e-25 88.3 1.7 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KFX97056.1 - 5.6e-20 71.8 0.4 1.4e-19 70.5 0.1 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFX97056.1 - 0.003 17.5 0.2 0.014 15.5 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97056.1 - 0.18 12.5 1.6 0.6 10.8 0.5 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 KFX97057.1 - 1.1e-63 214.1 0.0 1.6e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFX97057.1 - 1.1e-09 37.8 0.9 2.3e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KFX97057.1 - 0.018 15.5 0.0 0.052 14.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97057.1 - 0.035 14.4 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Dynein_heavy PF03028.15 KFX97057.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain NAM-associated PF14303.6 KFX97057.1 - 2.4 8.9 11.1 4.3 8.0 11.1 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain adh_short PF00106.25 KFX97059.1 - 6.6e-24 84.4 0.0 4.3e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97059.1 - 1.3e-14 54.4 0.0 6.7e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97059.1 - 4.6e-05 23.4 0.3 7e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KFX97059.1 - 0.21 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KFX97060.1 - 1.1e-08 35.6 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KFX97060.1 - 6.4e-05 23.0 0.1 9.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFX97060.1 - 0.002 18.4 0.0 0.0059 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX97060.1 - 0.0084 15.8 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KFX97060.1 - 0.056 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFX97060.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 KFX97060.1 - 0.14 12.0 0.1 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Myb_DNA-binding PF00249.31 KFX97061.1 - 4.4e-22 78.0 5.8 5.6e-12 45.7 0.7 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX97061.1 - 5.9e-17 61.7 8.8 9.7e-12 45.0 0.8 3.3 3 1 1 4 4 4 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFX97061.1 - 0.00067 19.9 3.3 1.3 9.4 0.5 3.4 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like PriCT_2 PF08707.11 KFX97061.1 - 0.013 15.9 1.2 2.9 8.3 0.1 2.8 2 1 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Myb_DNA-bind_4 PF13837.6 KFX97061.1 - 0.055 13.9 5.8 0.31 11.5 0.5 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 KFX97061.1 - 2.5 8.3 8.8 0.51 10.5 0.2 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Fer4 PF00037.27 KFX97062.1 - 1.6e-13 49.9 16.5 6.1e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFX97062.1 - 5.5e-13 49.3 10.1 9.2e-13 48.6 10.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFX97062.1 - 5.9e-10 39.9 8.2 6.7e-05 23.7 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KFX97062.1 - 1.2e-09 38.1 4.9 0.0002 21.4 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFX97062.1 - 1e-08 35.1 21.1 2.2e-06 27.7 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFX97062.1 - 1.6e-08 34.9 3.2 0.00028 21.3 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFX97062.1 - 2.9e-08 33.7 10.1 6e-08 32.7 10.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFX97062.1 - 1.5e-06 28.0 17.1 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KFX97062.1 - 4.5e-06 26.4 11.8 0.0098 15.9 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KFX97062.1 - 8.6e-06 25.9 11.4 0.0003 21.1 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KFX97062.1 - 0.00018 21.9 11.1 0.04 14.5 11.9 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KFX97062.1 - 0.015 15.5 5.9 0.33 11.2 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KFX97062.1 - 0.069 13.7 15.3 0.74 10.4 4.3 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KFX97062.1 - 0.072 13.3 8.9 1.2 9.3 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KFX97062.1 - 0.094 12.9 5.7 0.46 10.6 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 KFX97062.1 - 0.21 12.6 15.5 0.42 11.7 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KFX97062.1 - 0.52 11.2 11.5 3.5 8.5 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 KFX97063.1 - 3.4e-11 43.3 0.1 4.4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFX97063.1 - 5.6e-07 29.7 0.1 7.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 KFX97064.1 - 2.8e-68 230.0 0.1 3.6e-68 229.6 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GRAM PF02893.20 KFX97067.1 - 1.3e-32 112.0 1.5 1.1e-20 73.6 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KFX97067.1 - 1.1e-28 100.0 0.0 2.3e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KFX97067.1 - 4.8e-13 49.5 0.1 1.7e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 PH domain WD40 PF00400.32 KFX97067.1 - 2e-06 28.4 4.4 2.5 9.1 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_11 PF15413.6 KFX97067.1 - 0.0004 20.8 0.2 0.0051 17.2 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFX97067.1 - 0.00077 19.7 0.1 0.0026 18.0 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 KFX97067.1 - 0.0054 17.0 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 KFX97067.1 - 0.017 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PPR_2 PF13041.6 KFX97068.1 - 0.04 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SNF2_N PF00176.23 KFX97069.1 - 8.9e-58 195.7 0.0 1.8e-57 194.7 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KFX97069.1 - 1.6e-56 191.3 0.1 3.2e-56 190.4 0.1 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KFX97069.1 - 1.4e-15 57.6 0.0 5.6e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97069.1 - 7.4e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFX97069.1 - 0.012 14.9 0.0 0.043 13.0 0.0 1.9 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFX97069.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Mito_carr PF00153.27 KFX97070.1 - 1.4e-48 162.7 6.1 3.6e-20 71.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Heliorhodopsin PF18761.1 KFX97070.1 - 0.033 13.5 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Heliorhodopsin Thg1 PF04446.12 KFX97074.1 - 9.6e-53 177.5 0.0 2.3e-52 176.3 0.0 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFX97074.1 - 1.7e-50 170.2 0.2 2.3e-50 169.8 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain AlaDh_PNT_N PF05222.15 KFX97075.1 - 2.8e-28 98.9 0.0 4.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KFX97075.1 - 8.8e-05 21.9 0.0 0.00037 19.9 0.0 1.7 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KFX97080.1 - 3e-13 49.7 0.0 8.1e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX97080.1 - 9.6e-12 44.7 0.0 5.1e-09 35.7 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFX97080.1 - 7.1e-09 34.6 0.0 1.6e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX97080.1 - 5.6e-08 32.4 0.0 2.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX97080.1 - 0.00015 21.1 0.1 0.00034 19.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFX97080.1 - 0.00041 20.4 0.1 0.1 12.6 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX97080.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX97080.1 - 0.0048 16.5 0.1 2.4 7.6 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX97080.1 - 0.064 12.0 0.1 2.5 6.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein Methyltransf_25 PF13649.6 KFX97081.1 - 5.6e-16 59.0 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97081.1 - 3.4e-13 50.1 0.0 6.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97081.1 - 3e-11 43.4 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97081.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97081.1 - 5e-08 33.6 0.0 1e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX97081.1 - 3.3e-05 23.5 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KFX97081.1 - 4.2e-05 23.0 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KFX97081.1 - 0.00047 19.6 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Spermine_synth PF01564.17 KFX97081.1 - 0.0027 17.1 0.0 0.0066 15.9 0.0 1.5 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_16 PF10294.9 KFX97081.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase ApbA PF02558.16 KFX97081.1 - 0.0081 15.8 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Methyltransf_20 PF12147.8 KFX97081.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 KFX97081.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NodS PF05401.11 KFX97081.1 - 0.036 13.7 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 KFX97081.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Glyco_transf_4 PF13439.6 KFX97081.1 - 0.096 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 adh_short PF00106.25 KFX97081.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RrnaAD PF00398.20 KFX97081.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase 3HCDH_N PF02737.18 KFX97081.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cellulase PF00150.18 KFX97082.1 - 5.7e-52 176.9 1.7 7e-52 176.6 1.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFX97082.1 - 1e-11 44.6 16.0 1e-11 44.6 16.0 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Acetyltransf_7 PF13508.7 KFX97083.1 - 3.5e-05 24.1 0.1 9.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97083.1 - 5.2e-05 23.5 0.1 8.7e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX97083.1 - 0.00035 20.5 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX97083.1 - 0.0034 17.3 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein NAD_kinase PF01513.21 KFX97084.1 - 5.4e-46 157.1 0.0 8.5e-46 156.5 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Cyclin_C_2 PF16899.5 KFX97085.1 - 1.5e-30 105.6 0.5 2.9e-26 91.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Acyltransferase PF01553.21 KFX97085.1 - 1.1e-24 86.6 0.0 1.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KFX97085.1 - 4.8e-13 49.0 0.0 1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Cyclin_N PF00134.23 KFX97085.1 - 5e-08 32.7 0.1 9.1e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KFX97085.1 - 0.0068 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat CFEM PF05730.11 KFX97086.1 - 1.4e-09 37.9 10.1 2.6e-09 37.0 10.1 1.5 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.27 KFX97087.1 - 6e-49 166.1 0.0 2.9e-28 99.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX97087.1 - 4.3e-31 108.6 27.8 3.1e-23 82.8 11.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KFX97087.1 - 1e-11 45.2 5.4 0.017 15.0 0.0 4.6 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX97087.1 - 6.3e-10 38.9 4.4 0.11 11.9 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX97087.1 - 1.2e-08 34.6 0.8 0.00064 19.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFX97087.1 - 2.5e-07 30.8 0.3 0.012 15.7 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX97087.1 - 6.7e-06 26.6 0.3 0.16 12.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFX97087.1 - 8.4e-06 26.1 0.2 0.023 15.0 0.1 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX97087.1 - 1.1e-05 25.4 0.3 0.07 13.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 KFX97087.1 - 0.00037 19.9 0.4 0.23 10.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.6 KFX97087.1 - 0.00043 20.8 2.5 0.076 13.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFX97087.1 - 0.00049 19.7 1.7 0.06 12.9 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFX97087.1 - 0.00089 19.2 3.1 0.18 11.7 0.8 2.4 2 0 0 2 2 2 1 NTPase T2SSE PF00437.20 KFX97087.1 - 0.00098 18.3 0.4 0.015 14.4 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KFX97087.1 - 0.0024 17.4 0.2 0.81 9.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 KFX97087.1 - 0.0027 17.8 1.9 0.062 13.4 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KFX97087.1 - 0.003 17.3 0.2 0.22 11.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KFX97087.1 - 0.011 15.0 0.4 2.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Septin AAA PF00004.29 KFX97087.1 - 0.013 15.9 0.0 0.63 10.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KFX97087.1 - 0.014 15.5 4.1 0.11 12.5 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 KFX97087.1 - 0.022 14.0 0.1 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 KFX97087.1 - 0.026 13.5 0.7 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KFX97087.1 - 0.031 14.2 0.1 3.7 7.4 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KFX97087.1 - 0.032 13.9 0.7 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX97087.1 - 0.034 14.5 0.4 13 6.2 0.1 3.0 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 KFX97087.1 - 0.039 14.5 3.4 0.73 10.4 0.5 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX97087.1 - 0.041 13.1 1.3 2.9 7.0 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 KFX97087.1 - 0.045 13.5 0.9 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KFX97087.1 - 0.05 13.8 0.5 6.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 KFX97087.1 - 0.059 13.0 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KFX97087.1 - 0.062 13.2 1.0 8.9 6.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KFX97087.1 - 0.064 12.8 0.2 0.84 9.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KFX97087.1 - 0.07 12.0 1.7 5.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 KFX97087.1 - 0.13 11.6 0.8 9.9 5.4 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KFX97087.1 - 0.13 12.5 1.9 3.4 7.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KFX97087.1 - 0.17 11.6 2.4 0.26 11.0 0.3 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.26 KFX97087.1 - 0.17 11.6 0.0 23 4.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KFX97087.1 - 0.17 11.9 0.2 6.6 6.7 0.2 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KFX97087.1 - 0.5 10.1 1.4 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 KFX97087.1 - 0.78 9.0 2.3 17 4.7 0.3 3.0 3 0 0 3 3 3 0 KaiC SNF2_N PF00176.23 KFX97088.1 - 3.4e-64 216.8 0.4 6.4e-64 215.9 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFX97088.1 - 2.1e-49 167.3 20.0 2.1e-49 167.3 20.0 3.8 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 KFX97088.1 - 2.4e-19 69.7 0.0 1.4e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhyH PF05721.13 KFX97088.1 - 2.2e-06 28.1 0.5 1.1e-05 25.8 0.0 2.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) ResIII PF04851.15 KFX97088.1 - 2.6e-06 27.6 0.0 2.6e-06 27.6 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX97088.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFX97088.1 - 0.35 10.0 0.0 0.35 10.0 0.0 2.5 4 0 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 ABC_tran PF00005.27 KFX97089.1 - 1.4e-44 151.9 0.1 1.9e-21 77.0 0.1 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFX97089.1 - 3.4e-22 78.3 8.1 1.2e-21 76.5 3.1 3.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KFX97089.1 - 2.9e-18 66.7 0.2 0.0011 18.9 0.2 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX97089.1 - 8.7e-09 35.1 0.1 0.2 11.1 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX97089.1 - 1.7e-08 35.2 2.9 0.0039 17.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KFX97089.1 - 2.9e-07 30.1 0.9 0.0029 17.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KFX97089.1 - 3.4e-07 30.3 0.0 0.034 13.8 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX97089.1 - 1.3e-06 28.4 0.5 0.0013 18.6 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KFX97089.1 - 3.3e-05 24.3 0.0 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFX97089.1 - 4.4e-05 24.0 0.0 0.33 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFX97089.1 - 6.3e-05 23.0 0.0 0.05 13.7 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFX97089.1 - 0.00011 22.5 0.0 0.091 13.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX97089.1 - 0.00012 22.4 1.5 1 9.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 KFX97089.1 - 0.00016 21.9 0.0 0.058 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX97089.1 - 0.0003 20.6 1.9 1.4 8.6 0.1 3.8 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 KFX97089.1 - 0.00075 19.5 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 KFX97089.1 - 0.0028 18.1 0.0 1.2 9.5 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX97089.1 - 0.003 17.6 0.1 0.88 9.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFX97089.1 - 0.004 17.3 0.4 0.68 10.1 0.1 3.0 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 KFX97089.1 - 0.0051 16.0 0.6 0.42 9.7 0.0 3.4 4 0 0 4 4 4 1 NB-ARC domain AAA_27 PF13514.6 KFX97089.1 - 0.0053 16.4 0.0 4.1 6.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 KFX97089.1 - 0.0056 16.6 0.0 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Roc PF08477.13 KFX97089.1 - 0.013 15.8 0.2 6.8 6.9 0.1 3.1 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2813 PF11398.8 KFX97089.1 - 0.028 13.7 0.4 9 5.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 KFX97089.1 - 0.031 14.3 0.2 18 5.3 0.0 3.3 3 0 0 3 3 3 0 Dynamin family AAA_17 PF13207.6 KFX97089.1 - 0.046 14.1 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KFX97089.1 - 0.05 13.6 0.0 5.9 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX97089.1 - 0.061 13.0 2.8 0.4 10.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KFX97089.1 - 0.063 12.9 0.1 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX97089.1 - 0.063 12.8 0.1 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 KFX97089.1 - 0.1 11.7 0.0 8.4 5.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain VirE PF05272.11 KFX97089.1 - 0.1 12.3 0.1 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.9 KFX97089.1 - 0.12 11.5 0.5 13 4.8 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 KFX97089.1 - 0.13 11.4 0.5 3.7 6.6 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit MeaB PF03308.16 KFX97089.1 - 0.14 11.1 0.1 10 5.0 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 KFX97089.1 - 0.15 12.0 0.5 6.9 6.7 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KFX97089.1 - 0.16 11.5 0.0 4 6.9 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 KFX97089.1 - 0.57 10.1 2.8 2.1 8.2 0.2 2.8 3 0 0 3 3 3 0 NTPase Zn_clus PF00172.18 KFX97090.1 - 2.8e-05 24.2 9.4 4.7e-05 23.4 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX97091.1 - 9.3e-42 143.2 42.4 9.3e-42 143.2 42.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97091.1 - 4.7e-11 42.2 15.9 4.7e-11 42.2 15.9 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFX97091.1 - 4.9e-11 41.8 22.7 7.7e-11 41.1 22.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KFX97092.1 - 3.3e-06 26.3 0.0 4.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX97092.1 - 9.8e-06 25.6 2.6 2.2e-05 24.5 2.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX97093.1 - 1.7e-39 135.3 0.0 2.4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97093.1 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97093.1 - 5.1e-09 36.3 0.1 9.5e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFX97093.1 - 8.8e-05 22.0 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFX97093.1 - 0.00042 19.8 0.0 0.0013 18.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX97093.1 - 0.00063 19.7 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFX97093.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFX97093.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MUG113 PF13455.6 KFX97094.1 - 4.7e-26 91.3 0.6 9.4e-26 90.3 0.1 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KFX97094.1 - 2.6e-25 88.9 0.5 9.8e-25 87.1 0.0 2.2 3 0 0 3 3 3 1 T5orf172 domain Radical_SAM_C PF16199.5 KFX97095.1 - 3.2e-32 110.4 0.0 6.6e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFX97095.1 - 1.8e-16 60.9 0.0 5.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFX97095.1 - 5e-09 36.4 0.0 9.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX97095.1 - 1.3e-06 28.3 0.2 3.3e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX97095.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Adap_comp_sub PF00928.21 KFX97096.1 - 8.1e-85 284.4 0.0 1.1e-84 284.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CoA_binding PF02629.19 KFX97096.1 - 1.5e-26 92.9 1.2 1.5e-26 92.9 1.2 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFX97096.1 - 9.2e-23 80.8 0.1 1.6e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFX97096.1 - 3.6e-09 36.5 0.0 7.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFX97096.1 - 0.00042 20.8 0.1 0.0013 19.2 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain Clat_adaptor_s PF01217.20 KFX97096.1 - 0.0035 17.3 0.1 0.008 16.1 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KFX97096.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal GFO_IDH_MocA PF01408.22 KFX97097.1 - 3.3e-17 63.4 0.1 5.9e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX97097.1 - 0.0007 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KFX97097.1 - 0.081 13.4 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Gly_transf_sug PF04488.15 KFX97114.1 - 1.1e-21 77.3 0.1 2.3e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DNA_pol_A_exo1 PF01612.20 KFX97114.1 - 9.4e-09 35.2 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Reoviridae_Vp9 PF08978.10 KFX97114.1 - 0.14 11.3 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Reoviridae VP9 THF_DHG_CYH PF00763.23 KFX97117.1 - 1.4e-21 76.9 0.0 2.6e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KFX97117.1 - 6.9e-15 54.7 0.0 5.4e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ERCC4 PF02732.15 KFX97118.1 - 9.1e-27 94.2 0.0 1.6e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain CMV_US PF08001.11 KFX97118.1 - 0.098 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 CMV US EMC3_TMCO1 PF01956.16 KFX97119.1 - 7.6e-10 38.8 0.2 1.1e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ADH_zinc_N PF00107.26 KFX97125.1 - 2.4e-32 111.6 3.0 6.7e-32 110.2 2.7 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ubiquitin PF00240.23 KFX97125.1 - 1.7e-18 66.1 0.1 2.6e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family ADH_zinc_N_2 PF13602.6 KFX97125.1 - 4.1e-13 50.5 0.0 9.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UBA PF00627.31 KFX97125.1 - 7.9e-05 22.5 0.1 0.00021 21.1 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KFX97125.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KFX97125.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFX97125.1 - 0.00019 21.9 0.0 0.00036 21.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain GerD PF17898.1 KFX97125.1 - 0.013 15.4 2.7 0.024 14.6 2.7 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain adh_short PF00106.25 KFX97125.1 - 0.069 12.6 2.4 0.088 12.3 1.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase STI1 PF17830.1 KFX97125.1 - 0.1 12.6 15.1 0.044 13.7 6.0 2.7 2 0 0 2 2 2 0 STI1 domain HupF_HypC PF01455.18 KFX97125.1 - 0.18 12.0 0.9 1.9 8.7 0.3 2.6 2 1 0 2 2 2 0 HupF/HypC family Ldh_2 PF02615.14 KFX97131.1 - 2.7e-100 335.8 3.7 3e-100 335.6 3.7 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Hydrolase PF00702.26 KFX97133.1 - 0.00042 20.7 0.0 0.0036 17.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KFX97133.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Ribosomal_L20 PF00453.18 KFX97133.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 bZIP_2 PF07716.15 KFX97134.1 - 1.3e-05 25.1 4.0 2.3e-05 24.4 4.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFX97134.1 - 0.00044 20.7 5.1 0.001 19.5 5.1 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFX97134.1 - 0.0058 16.7 6.1 0.013 15.6 5.8 1.7 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 KFX97134.1 - 0.037 14.3 5.1 0.05 13.8 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPD52 PF04201.15 KFX97134.1 - 0.13 11.8 1.1 0.25 10.9 0.2 1.8 2 0 0 2 2 2 0 Tumour protein D52 family TolA_bind_tri PF16331.5 KFX97134.1 - 2.1 8.5 7.2 4 7.6 1.6 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1635 PF07795.11 KFX97134.1 - 4.5 7.1 11.6 0.13 12.1 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) TPR_10 PF13374.6 KFX97135.1 - 5.8e-43 143.6 15.8 4.1e-06 26.5 0.1 9.0 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KFX97135.1 - 3.9e-39 132.8 16.1 1.6e-11 44.3 0.9 5.0 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97135.1 - 3.6e-29 98.5 18.8 0.00091 19.3 0.1 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFX97135.1 - 4.1e-22 76.4 22.1 0.01 15.9 0.2 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 KFX97135.1 - 1.2e-21 75.8 15.9 0.012 16.2 0.2 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX97135.1 - 4.9e-21 74.7 15.0 0.0037 17.5 0.0 8.5 2 1 7 9 9 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFX97135.1 - 1.1e-16 61.1 27.3 0.0052 17.3 0.0 7.2 5 1 3 8 8 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97135.1 - 1.5e-16 60.8 5.8 0.00079 20.0 1.0 8.4 8 1 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97135.1 - 2e-16 59.3 15.9 0.015 16.1 0.0 8.7 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFX97135.1 - 4.2e-14 51.7 18.4 0.1 12.4 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFX97135.1 - 2.1e-13 50.4 24.3 0.034 14.5 0.3 8.8 2 1 7 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX97135.1 - 9e-13 47.3 13.7 0.14 12.3 0.1 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat PPR PF01535.20 KFX97135.1 - 1.5e-11 43.7 3.4 3.7 8.0 0.0 8.9 10 0 0 10 10 8 1 PPR repeat DUF4248 PF14053.6 KFX97135.1 - 3.1e-07 30.3 2.9 2.4 8.3 0.0 6.8 7 0 0 7 7 7 1 Domain of unknown function (DUF4248) MRP-S27 PF10037.9 KFX97135.1 - 4.3e-07 29.1 6.9 0.37 9.6 0.2 5.0 5 0 0 5 5 5 3 Mitochondrial 28S ribosomal protein S27 AAA_16 PF13191.6 KFX97135.1 - 1e-05 26.0 0.8 0.00027 21.3 0.0 3.2 2 1 1 3 3 2 1 AAA ATPase domain PGAP1 PF07819.13 KFX97135.1 - 6.3e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX97135.1 - 0.00015 22.5 0.2 0.00049 20.8 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family CbiA PF01656.23 KFX97135.1 - 0.00032 20.8 0.0 0.0035 17.4 0.0 2.8 3 2 0 3 3 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_17 PF13431.6 KFX97135.1 - 0.00035 20.7 13.8 0.95 10.0 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat LCAT PF02450.15 KFX97135.1 - 0.00043 19.6 0.0 0.00074 18.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Vps39_1 PF10366.9 KFX97135.1 - 0.00053 20.2 13.0 0.56 10.5 0.6 6.1 2 2 3 6 6 6 1 Vacuolar sorting protein 39 domain 1 DUF627 PF04781.12 KFX97135.1 - 0.00069 19.6 5.6 30 4.7 0.0 6.7 7 0 0 7 7 7 0 Protein of unknown function (DUF627) Abhydrolase_9 PF10081.9 KFX97135.1 - 0.0013 17.9 0.1 0.012 14.7 0.0 2.5 3 1 1 4 4 4 1 Alpha/beta-hydrolase family DUF726 PF05277.12 KFX97135.1 - 0.0014 17.7 0.1 0.0049 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF726) NB-ARC PF00931.22 KFX97135.1 - 0.0016 17.7 0.1 0.0041 16.3 0.1 1.7 1 1 0 1 1 1 1 NB-ARC domain UPF0052 PF01933.18 KFX97135.1 - 0.0029 16.9 3.3 6.4 5.9 0.2 5.3 2 1 2 4 4 3 0 Uncharacterised protein family UPF0052 Hydrolase_4 PF12146.8 KFX97135.1 - 0.0057 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KFX97135.1 - 0.0076 15.8 0.0 0.019 14.4 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_4 PF07721.14 KFX97135.1 - 0.014 15.9 11.8 0.39 11.5 0.4 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KFX97135.1 - 0.021 15.1 0.1 0.2 11.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain PPR_2 PF13041.6 KFX97135.1 - 0.025 14.8 5.5 88 3.4 0.0 6.2 8 0 0 8 8 7 0 PPR repeat family YfdX PF10938.8 KFX97135.1 - 0.033 14.1 14.4 0.36 10.8 4.0 5.3 1 1 1 3 3 3 0 YfdX protein AAA_30 PF13604.6 KFX97135.1 - 0.047 13.4 0.1 0.68 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain LIDHydrolase PF10230.9 KFX97135.1 - 0.14 11.6 0.4 0.57 9.7 0.0 2.2 3 0 0 3 3 2 0 Lipid-droplet associated hydrolase MIT PF04212.18 KFX97135.1 - 0.47 10.6 5.6 17 5.5 0.0 5.5 6 1 1 7 7 6 0 MIT (microtubule interacting and transport) domain DUF410 PF04190.13 KFX97135.1 - 3.7 7.3 10.3 16 5.1 7.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF410) Gly_transf_sug PF04488.15 KFX97136.1 - 8.1e-09 36.0 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFX97136.1 - 0.077 12.3 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF3149 PF11346.8 KFX97137.1 - 0.52 10.0 1.5 0.91 9.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Fungal_trans PF04082.18 KFX97138.1 - 2.7e-12 46.3 0.0 4.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX97138.1 - 2.2e-06 27.7 9.7 4e-06 26.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFX97141.1 - 1.3e-53 182.1 0.0 2.2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97141.1 - 8e-32 110.5 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX97141.1 - 5.7e-14 52.1 0.0 7.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pmp3 PF01679.17 KFX97155.1 - 2.9e-20 72.2 9.5 3.5e-20 71.9 9.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sin_N PF04801.13 KFX97156.1 - 1.8e-33 116.5 0.0 7.4e-19 68.3 0.0 2.0 2 0 0 2 2 2 2 Sin-like protein conserved region CLP1_P PF16575.5 KFX97157.1 - 1.1e-43 149.2 0.0 1.9e-43 148.4 0.0 1.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFX97157.1 - 8e-35 119.8 0.0 1.3e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KFX97157.1 - 6.2e-34 116.1 0.1 1.9e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 KFX97157.1 - 5e-08 33.0 0.0 5.5e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFX97157.1 - 0.0001 22.4 0.3 0.0014 18.7 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX97157.1 - 0.00027 21.4 0.0 0.00054 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFX97157.1 - 0.0039 16.6 0.0 0.0098 15.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFX97157.1 - 0.0041 17.2 0.3 1.1 9.2 0.0 2.6 2 1 1 3 3 3 1 Dynamin family AAA_21 PF13304.6 KFX97157.1 - 0.0057 16.5 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KFX97157.1 - 0.0088 15.8 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KFX97157.1 - 0.017 14.8 0.0 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFX97157.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFX97157.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFX97157.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MTS_N PF08468.11 KFX97157.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal AAA_35 PF14516.6 KFX97157.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TniB PF05621.11 KFX97157.1 - 0.16 11.4 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 KFX97157.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Arm PF00514.23 KFX97158.1 - 0.0082 16.2 1.9 0.2 11.8 0.1 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFX97158.1 - 0.01 16.3 0.4 3.2 8.4 0.1 3.4 2 0 0 2 2 2 0 HEAT-like repeat HEAT_2 PF13646.6 KFX97158.1 - 0.041 14.3 0.5 1.6 9.2 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KFX97158.1 - 0.069 13.4 0.2 3 8.3 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat BUD22 PF09073.10 KFX97158.1 - 0.15 11.4 9.6 0.23 10.8 9.6 1.2 1 0 0 1 1 1 0 BUD22 Baculo_PEP_C PF04513.12 KFX97158.1 - 0.16 12.0 2.4 2.5 8.1 0.3 3.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_pol_phi PF04931.13 KFX97158.1 - 1.4 7.0 20.0 2.7 6.0 20.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KFX97158.1 - 4.3 5.8 10.7 6.7 5.2 10.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RPA_C PF08784.11 KFX97159.1 - 2.9e-16 60.0 0.1 8.1e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFX97159.1 - 3.9e-10 39.6 0.1 1e-09 38.2 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFX97159.1 - 5.4e-06 26.2 0.1 8.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 KFX97159.1 - 0.27 10.9 0.1 0.4 10.4 0.1 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DnaJ PF00226.31 KFX97160.1 - 2.4e-14 53.2 2.1 1.1e-13 51.1 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain ALMT PF11744.8 KFX97160.1 - 6.2 5.5 8.0 6.1 5.6 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lon_C PF05362.13 KFX97161.1 - 5.4e-66 222.0 0.4 1.1e-65 221.1 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFX97161.1 - 8.5e-28 97.6 0.0 2e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFX97161.1 - 1.8e-23 83.4 0.0 6.9e-23 81.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX97161.1 - 1e-08 35.3 0.0 2.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KFX97161.1 - 3.3e-08 33.4 0.0 6.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase IstB_IS21 PF01695.17 KFX97161.1 - 4.8e-07 29.7 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFX97161.1 - 1.3e-05 25.6 0.5 5.2e-05 23.7 0.1 2.3 1 1 1 2 2 1 1 AAA ATPase domain AAA_2 PF07724.14 KFX97161.1 - 4.3e-05 23.7 0.0 0.00015 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFX97161.1 - 4.8e-05 23.2 0.1 0.00022 21.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX97161.1 - 5.4e-05 23.1 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX97161.1 - 0.0008 19.7 0.2 0.015 15.6 0.0 3.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 KFX97161.1 - 0.0015 17.8 0.2 0.0027 17.0 0.2 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KFX97161.1 - 0.003 17.1 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFX97161.1 - 0.0053 16.9 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX97161.1 - 0.0065 16.9 0.0 0.024 15.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 KFX97161.1 - 0.0072 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX97161.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KFX97161.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TelA PF05816.11 KFX97161.1 - 0.026 13.6 4.9 0.059 12.4 4.9 1.5 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_18 PF13238.6 KFX97161.1 - 0.027 15.0 0.0 0.07 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFX97161.1 - 0.028 13.8 0.2 0.096 12.1 0.2 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KFX97161.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KFX97161.1 - 0.035 14.6 0.0 0.035 14.6 0.0 2.6 1 1 1 2 2 1 0 AAA domain TsaE PF02367.17 KFX97161.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KFX97161.1 - 0.061 13.2 0.0 0.97 9.3 0.0 2.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_PrkA PF08298.11 KFX97161.1 - 0.062 12.2 0.1 0.59 9.0 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain NB-ARC PF00931.22 KFX97161.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KFX97161.1 - 0.08 13.5 0.0 0.31 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KFX97161.1 - 0.091 12.7 1.0 0.27 11.1 0.1 2.2 2 1 0 2 2 2 0 NTPase AAA_24 PF13479.6 KFX97161.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFX97161.1 - 0.12 12.0 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFX97161.1 - 1.6 8.4 5.8 0.8 9.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Laps PF10169.9 KFX97161.1 - 2.5 8.7 9.7 0.28 11.8 0.4 2.4 1 1 1 2 2 2 0 Learning-associated protein Pribosyltran PF00156.27 KFX97171.1 - 2.3e-17 63.0 0.0 3.3e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFX97171.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase_Tyr PF07714.17 KFX97192.1 - 4.7e-18 65.4 0.0 9.1e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFX97192.1 - 8e-18 64.8 0.0 1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX97192.1 - 0.0029 17.6 1.1 0.005 16.8 1.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX97192.1 - 0.036 13.6 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFX97192.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX97192.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Cellulase PF00150.18 KFX97200.1 - 2.3e-30 106.0 0.4 4.3e-30 105.1 0.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_20 PF00728.22 KFX97201.1 - 2.1e-28 99.7 0.0 5.8e-26 91.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KFX97201.1 - 2.2e-10 41.4 0.0 4.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Collagen PF01391.18 KFX97203.1 - 9.6 6.1 13.1 0.65 9.8 7.3 2.0 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Kdo PF06293.14 KFX97204.1 - 0.03 13.7 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HeLo PF14479.6 KFX97204.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation zf-RanBP PF00641.18 KFX97206.1 - 6.2e-12 44.6 1.1 9.1e-12 44.1 1.1 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KFX97206.1 - 3.3e-08 33.2 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX97206.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Coatomer_E PF04733.14 KFX97209.1 - 2.3e-57 194.6 10.0 2.6e-57 194.5 10.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFX97209.1 - 7.1e-11 42.5 24.8 4.5e-05 23.9 0.9 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97209.1 - 3.2e-08 33.7 20.0 0.0001 22.8 0.2 5.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97209.1 - 1.9e-07 31.6 20.6 0.011 16.4 0.1 4.9 2 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX97209.1 - 1.5e-05 25.1 6.5 0.0038 17.4 0.3 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 KFX97209.1 - 2.6e-05 24.2 1.4 0.0019 18.2 0.2 2.4 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_4 PF07721.14 KFX97209.1 - 2.9e-05 24.3 10.2 0.35 11.6 0.3 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX97209.1 - 5.9e-05 23.4 8.1 0.02 15.5 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97209.1 - 0.00011 22.1 7.8 0.41 11.0 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX97209.1 - 0.00035 20.5 17.4 0.0012 18.8 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX97209.1 - 0.0015 18.8 16.1 0.068 13.5 0.6 4.5 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFX97209.1 - 0.0018 18.0 4.5 0.021 14.5 0.0 3.9 5 0 0 5 5 5 1 TPR repeat TPR_1 PF00515.28 KFX97209.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX97209.1 - 0.068 13.6 3.6 0.32 11.5 0.0 3.8 5 1 1 6 6 5 0 Tetratricopeptide repeat Tcf25 PF04910.14 KFX97209.1 - 0.12 11.4 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 NARP1 PF12569.8 KFX97209.1 - 0.15 11.0 4.8 0.48 9.3 0.0 2.5 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 DUF1488 PF07369.11 KFX97209.1 - 0.23 11.5 3.3 6.6 6.8 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1488) TPR_9 PF13371.6 KFX97209.1 - 3 8.1 9.9 1.8 8.8 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KFX97209.1 - 4.6 7.4 12.4 0.28 11.3 0.3 4.0 3 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 HAD PF12710.7 KFX97211.1 - 2.2e-24 86.9 0.0 2.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFX97211.1 - 0.0036 16.7 0.0 0.23 10.9 0.0 2.4 3 0 0 3 3 3 1 Putative Phosphatase Herpes_US12 PF05363.12 KFX97211.1 - 0.037 14.7 0.0 14 6.5 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus US12 family Hydrolase PF00702.26 KFX97211.1 - 0.043 14.1 0.2 0.15 12.4 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFX97211.1 - 0.083 12.4 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Herpes_teg_N PF04843.12 KFX97211.1 - 0.13 12.0 0.0 9.5 5.9 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region Lipase_GDSL_2 PF13472.6 KFX97212.1 - 3.6e-10 40.5 0.0 1.2e-07 32.3 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DUF4992 PF16383.5 KFX97212.1 - 0.15 11.6 0.5 5.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Chitin_synth_2 PF03142.15 KFX97217.1 - 6.4e-248 823.6 1.0 1e-247 822.9 1.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KFX97217.1 - 2e-68 231.2 0.0 2.2e-67 227.8 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KFX97217.1 - 7.5e-15 54.6 0.0 3.3e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KFX97217.1 - 2.8e-13 49.8 0.0 1.5e-10 41.1 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KFX97217.1 - 1e-11 45.1 4.1 1e-11 45.1 4.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFX97217.1 - 1.3e-11 44.9 0.0 2.9e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX97217.1 - 3.6e-05 23.6 0.0 0.064 13.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Cellulase PF00150.18 KFX97220.1 - 4.4e-51 174.0 0.1 6.1e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFX97220.1 - 1.7e-12 47.0 14.7 1.7e-12 47.0 14.7 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX97220.1 - 0.63 10.3 3.8 1.5 9.1 3.8 1.7 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_10 PF00331.20 KFX97221.1 - 2.2e-104 349.0 0.2 2.6e-104 348.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KFX97221.1 - 7.4e-08 32.2 7.8 7.4e-08 32.2 7.8 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.13 KFX97222.1 - 2.6e-152 505.8 14.3 3.2e-152 505.5 14.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KFX97222.1 - 2.7e-12 46.4 16.7 9.4e-12 44.7 16.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.18 KFX97223.1 - 3.7e-07 30.0 11.4 3.7e-07 30.0 11.4 3.3 4 0 0 4 4 4 1 Fungal cellulose binding domain Esterase_phd PF10503.9 KFX97223.1 - 0.0036 16.8 0.7 0.017 14.6 0.3 2.1 1 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX97223.1 - 0.0058 16.1 0.0 0.024 14.1 0.2 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KFX97223.1 - 0.0098 15.6 1.6 0.044 13.4 1.6 1.9 1 1 0 1 1 1 1 Putative esterase MSP1_C PF07462.11 KFX97223.1 - 0.41 9.3 0.3 0.52 8.9 0.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Abhydrolase_6 PF12697.7 KFX97224.1 - 9e-15 55.9 0.0 1.1e-14 55.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX97224.1 - 0.018 14.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Zeta_toxin PF06414.12 KFX97224.1 - 0.023 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Hydrolase_4 PF12146.8 KFX97224.1 - 0.054 12.7 0.0 0.27 10.5 0.0 2.0 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KFX97224.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family TLP1_add_C PF18313.1 KFX97225.1 - 3.3e-27 94.2 0.1 7.3e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain RhoGEF PF00621.20 KFX97226.1 - 1.5e-23 84.0 0.0 3.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KFX97226.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 KFX97226.1 - 0.049 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Seryl_tRNA_N PF02403.22 KFX97226.1 - 1.6 9.0 12.0 0.61 10.4 6.5 2.9 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Carn_acyltransf PF00755.20 KFX97227.1 - 5.4e-209 695.7 0.0 8.6e-209 695.0 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase TPR_12 PF13424.6 KFX97228.1 - 9.5e-42 141.2 16.1 1.4e-10 41.3 0.0 5.4 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFX97228.1 - 1.2e-30 104.5 7.0 6.5e-07 29.0 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFX97228.1 - 6.3e-13 47.8 0.5 0.0055 16.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX97228.1 - 8.3e-10 38.0 4.5 0.14 12.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97228.1 - 2.3e-09 36.7 2.6 0.072 13.3 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFX97228.1 - 8.2e-09 34.9 0.6 0.0058 16.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97228.1 - 1.7e-07 31.4 3.2 0.5 11.3 0.0 5.4 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97228.1 - 1e-06 29.2 0.5 2.6 8.8 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX97228.1 - 1.5e-06 27.8 0.4 0.00098 18.6 0.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region RPN7 PF10602.9 KFX97228.1 - 0.011 15.5 0.0 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF2989 PF11207.8 KFX97228.1 - 0.035 13.9 0.2 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_6 PF13174.6 KFX97228.1 - 0.059 14.0 0.5 8.4 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX97228.1 - 0.08 13.3 0.7 8.3 7.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX97228.1 - 0.15 12.3 0.3 31 4.9 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFX97228.1 - 0.18 12.1 0.3 19 5.7 0.0 3.4 4 0 0 4 4 2 0 PPR repeat TPR_4 PF07721.14 KFX97228.1 - 0.19 12.4 2.0 20 6.2 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1897 PF09005.10 KFX97228.1 - 2 7.9 4.9 1.5 8.4 0.2 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF1897) MFS_1 PF07690.16 KFX97229.1 - 6.6e-30 104.2 68.4 8.5e-25 87.4 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 KFX97229.1 - 9.9e-05 21.1 2.4 9.9e-05 21.1 2.4 1.8 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like TPR_12 PF13424.6 KFX97230.1 - 4.2e-34 116.7 9.8 4.2e-11 43.0 0.1 6.4 2 1 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFX97230.1 - 5.1e-24 83.4 3.1 0.001 18.8 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX97230.1 - 1.3e-09 37.9 7.9 5.3e-08 32.6 0.8 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_19 PF14559.6 KFX97230.1 - 1.4e-06 28.7 4.9 0.34 11.4 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX97230.1 - 1.8e-06 27.6 5.3 0.62 10.2 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97230.1 - 8.4e-06 26.3 0.0 0.34 11.6 0.0 5.1 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97230.1 - 3.5e-05 24.2 1.6 0.48 11.4 0.1 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97230.1 - 0.00014 21.8 5.2 1.1 9.7 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX97230.1 - 0.0004 20.1 0.4 13 5.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KFX97230.1 - 0.0011 19.1 2.8 7.8 7.0 0.1 4.8 5 0 0 5 5 5 1 PPR repeat TPR_2 PF07719.17 KFX97230.1 - 0.0044 17.0 6.4 4.5 7.6 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFX97230.1 - 0.0049 17.4 0.1 1 10.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NB-ARC PF00931.22 KFX97230.1 - 0.0056 15.9 0.0 0.032 13.4 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFX97230.1 - 0.044 14.2 0.0 0.32 11.4 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain ANAPC3 PF12895.7 KFX97230.1 - 0.053 13.8 0.3 3.8 7.8 0.0 3.9 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ATPase_2 PF01637.18 KFX97230.1 - 0.064 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ANAPC5 PF12862.7 KFX97230.1 - 0.07 13.2 0.0 6 7.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 CbiA PF01656.23 KFX97230.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4919 PF16266.5 KFX97230.1 - 0.14 12.1 0.1 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) p450 PF00067.22 KFX97231.1 - 3.6e-59 200.7 0.0 5e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 KFX97232.1 - 1.2e-05 24.3 0.2 1.8e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTAD PF03704.17 KFX97232.1 - 0.048 14.1 0.5 2.8 8.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Glyco_transf_28 PF03033.20 KFX97233.1 - 3e-17 62.9 1.1 6.5e-12 45.7 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase family 28 N-terminal domain UIM PF02809.20 KFX97233.1 - 0.00021 21.0 0.5 1.7 8.7 0.0 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif UDPGT PF00201.18 KFX97233.1 - 0.00057 18.8 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX97233.1 - 0.025 14.5 0.0 0.32 11.0 0.0 2.9 3 0 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 KFX97233.1 - 0.058 13.2 0.3 0.2 11.4 0.3 1.9 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal zf-CRD PF17979.1 KFX97234.1 - 0.0045 17.1 2.1 0.0059 16.7 2.1 1.1 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions zf-AN1 PF01428.16 KFX97234.1 - 0.069 13.3 0.2 0.069 13.3 0.2 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger DUF2306 PF10067.9 KFX97236.1 - 2.7e-15 56.8 13.5 5.9e-15 55.7 13.5 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Zn_clus PF00172.18 KFX97237.1 - 1.8e-07 31.2 7.7 2.9e-07 30.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX97237.1 - 0.00068 18.6 0.0 0.0021 17.0 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain LysM PF01476.20 KFX97238.1 - 4.2e-23 81.1 4.1 2.4e-07 30.7 0.2 4.5 4 0 0 4 4 4 3 LysM domain HTH_Tnp_1 PF01527.20 KFX97238.1 - 0.015 15.6 0.0 2.3 8.6 0.0 2.8 4 0 0 4 4 4 0 Transposase Aspzincin_M35 PF14521.6 KFX97238.1 - 0.17 12.4 2.3 11 6.6 0.1 2.5 1 1 1 2 2 2 0 Lysine-specific metallo-endopeptidase ABC_tran PF00005.27 KFX97240.1 - 5.7e-43 146.7 0.1 1.2e-22 80.9 0.4 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX97240.1 - 5.4e-37 127.9 28.2 2.1e-27 96.5 6.8 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KFX97240.1 - 2.3e-08 34.2 1.1 0.0034 17.2 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX97240.1 - 1.2e-07 31.4 0.9 0.00014 21.4 0.1 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX97240.1 - 4.5e-07 30.2 0.1 0.019 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX97240.1 - 1e-06 28.4 1.7 0.025 14.3 0.2 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX97240.1 - 2e-05 25.2 2.2 0.0057 17.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX97240.1 - 7.2e-05 22.7 1.4 0.067 13.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KFX97240.1 - 0.00019 21.0 0.6 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFX97240.1 - 0.00025 20.5 0.6 0.22 10.8 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 KFX97240.1 - 0.00066 20.1 0.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KFX97240.1 - 0.001 19.0 0.6 0.036 14.0 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_15 PF13175.6 KFX97240.1 - 0.003 17.3 4.8 0.014 15.1 0.6 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KFX97240.1 - 0.0039 17.3 1.9 0.67 10.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KFX97240.1 - 0.0049 16.0 3.0 0.93 8.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.6 KFX97240.1 - 0.007 16.5 0.0 0.6 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX97240.1 - 0.0093 16.3 0.2 0.85 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KFX97240.1 - 0.02 14.5 0.3 7.7 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFX97240.1 - 0.025 14.0 0.4 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KFX97240.1 - 0.025 14.3 0.2 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFX97240.1 - 0.044 13.7 0.2 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KFX97240.1 - 0.073 13.1 0.9 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KFX97240.1 - 0.086 13.4 0.0 40 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KFX97240.1 - 0.093 11.9 0.7 0.79 8.8 0.1 2.4 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KFX97240.1 - 0.1 12.2 1.8 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 KFX97240.1 - 0.12 11.1 1.1 0.58 8.9 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Roc PF08477.13 KFX97240.1 - 0.13 12.5 0.3 23 5.2 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KFX97240.1 - 0.13 12.3 4.9 0.4 10.7 0.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 KFX97240.1 - 0.18 12.2 0.1 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFX97240.1 - 0.19 11.8 0.1 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KFX97240.1 - 0.2 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFX97240.1 - 0.2 11.6 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 KFX97240.1 - 0.31 10.7 0.6 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Guanylate kinase Pox_A32 PF04665.12 KFX97240.1 - 0.31 10.4 0.9 22 4.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.29 KFX97248.1 - 4.6e-47 159.8 0.0 6.1e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX97248.1 - 8.9e-09 35.0 0.4 1.8e-08 34.0 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX97248.1 - 1.4e-07 32.1 0.1 8.2e-05 23.1 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KFX97248.1 - 2e-06 27.6 0.0 7.3e-06 25.8 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFX97248.1 - 5.6e-05 23.4 0.0 0.0069 16.7 0.0 2.4 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 KFX97248.1 - 0.0001 22.4 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFX97248.1 - 0.00036 20.5 0.1 0.0027 17.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFX97248.1 - 0.00046 20.4 0.0 0.00085 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFX97248.1 - 0.0028 17.1 0.1 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFX97248.1 - 0.0033 17.5 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX97248.1 - 0.0042 16.3 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KFX97248.1 - 0.0046 16.2 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Zeta_toxin PF06414.12 KFX97248.1 - 0.005 16.1 0.0 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 KFX97248.1 - 0.0083 16.1 0.1 0.23 11.4 0.0 2.1 1 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 KFX97248.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX97248.1 - 0.013 15.8 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KFX97248.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KFX97248.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFX97248.1 - 0.015 15.8 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFX97248.1 - 0.019 15.5 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX97248.1 - 0.024 14.9 0.0 0.062 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFX97248.1 - 0.042 13.8 0.0 0.43 10.4 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KFX97248.1 - 0.042 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KFX97248.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KFX97248.1 - 0.044 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KFX97248.1 - 0.063 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFX97248.1 - 0.065 12.8 0.1 0.88 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX97248.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 KFX97248.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_24 PF13479.6 KFX97248.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX97248.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KFX97248.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFX97248.1 - 0.27 10.3 0.0 0.4 9.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2293 PF10056.9 KFX97249.1 - 6.7e-31 106.4 0.1 1.5e-30 105.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.27 KFX97250.1 - 1.6e-40 136.9 10.2 3.8e-16 58.8 0.8 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.25 KFX97251.1 - 1.1e-33 115.1 0.6 8.1e-21 73.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFX97251.1 - 5.4e-11 42.5 0.5 5.4e-11 42.5 0.5 2.5 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation YlbD_coat PF14071.6 KFX97251.1 - 1 9.6 7.7 1.1 9.6 4.1 2.5 2 0 0 2 2 2 0 Putative coat protein RNase_PH PF01138.21 KFX97252.1 - 6.6e-14 52.5 0.0 2e-13 51.0 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFX97252.1 - 0.0076 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATE_C PF04377.15 KFX97253.1 - 1.8e-44 151.6 0.1 4e-44 150.5 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFX97253.1 - 1.9e-24 85.8 2.2 3.8e-24 84.9 2.2 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KFX97253.1 - 0.0042 17.2 0.5 0.0096 16.1 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kinesin PF00225.23 KFX97256.1 - 1.1e-113 379.5 0.3 2.4e-113 378.4 0.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX97256.1 - 3.6e-26 91.9 0.0 1.2e-25 90.2 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 KFX97256.1 - 0.086 12.9 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) RolB_RolC PF02027.17 KFX97256.1 - 0.7 9.5 4.1 0.77 9.4 0.2 2.7 3 0 0 3 3 3 0 RolB/RolC glucosidase family UQ_con PF00179.26 KFX97257.1 - 4.3e-52 175.5 0.0 4.9e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX97257.1 - 0.0029 17.3 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFX97257.1 - 0.032 14.5 0.0 0.037 14.3 0.0 1.3 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KFX97258.1 - 4.1e-90 301.7 0.8 7.3e-90 300.8 0.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX97258.1 - 1.6e-36 124.6 1.3 4.2e-36 123.3 1.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX97258.1 - 0.0011 18.6 0.7 0.0026 17.4 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFX97258.1 - 0.071 13.0 2.7 11 5.9 0.1 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DJ-1_PfpI PF01965.24 KFX97259.1 - 5.3e-06 26.3 0.0 3.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family DUF1524 PF07510.11 KFX97264.1 - 2.9e-10 40.2 0.0 3.3e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KFX97264.1 - 0.024 14.5 0.5 0.094 12.6 0.5 1.9 1 1 0 1 1 1 0 HNH endonuclease Acyl-CoA_dh_1 PF00441.24 KFX97265.1 - 1.2e-25 90.4 0.4 2.5e-25 89.5 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX97265.1 - 3.1e-20 72.2 0.0 7.6e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.23 KFX97265.1 - 2.9e-16 59.6 0.2 7.4e-15 55.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Acyl-CoA_dh_2 PF08028.11 KFX97265.1 - 3.3e-13 50.1 0.5 9.2e-13 48.6 0.5 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX97265.1 - 1.5e-11 45.0 0.0 4.9e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FeoB_N PF02421.18 KFX97265.1 - 1.6e-07 31.0 0.3 8.9e-06 25.3 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFX97265.1 - 1.5e-05 25.0 0.5 0.0016 18.4 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KFX97265.1 - 0.011 15.8 3.2 0.23 11.5 0.1 3.1 4 0 0 4 4 4 0 Dynamin family AIG1 PF04548.16 KFX97265.1 - 0.012 14.9 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 AIG1 family DUF5523 PF17661.1 KFX97265.1 - 3.9 7.1 14.6 0.14 11.8 8.7 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Astro_capsid_p PF12226.8 KFX97265.1 - 6.5 5.8 7.5 12 4.9 7.5 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LTV PF04180.14 KFX97266.1 - 8.8e-128 427.3 18.3 1.1e-127 427.0 18.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein GST_N_2 PF13409.6 KFX97267.1 - 1.8e-06 28.2 0.0 3.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX97267.1 - 1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX97267.1 - 0.00037 20.5 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX97267.1 - 0.0004 20.5 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX97267.1 - 0.0044 17.2 0.0 0.0092 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFX97267.1 - 0.085 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spo12 PF05032.12 KFX97268.1 - 1.4e-17 63.3 3.6 2.2e-17 62.7 1.5 2.3 3 0 0 3 3 3 1 Spo12 family AMP-binding PF00501.28 KFX97278.1 - 9.3e-148 492.3 0.3 6.4e-64 216.1 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFX97278.1 - 7.1e-112 374.4 0.0 7.3e-37 127.1 0.0 5.4 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KFX97278.1 - 1.6e-20 73.2 2.6 1.1e-09 38.5 0.2 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX97278.1 - 0.003 18.5 0.0 3.9 8.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Amidase PF01425.21 KFX97279.1 - 1.2e-97 327.8 0.0 7.5e-97 325.1 0.0 1.9 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 KFX97280.1 - 1.4e-29 103.1 67.6 2.1e-15 56.5 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CRCB PF02537.15 KFX97281.1 - 8.5e-36 122.2 14.1 1.3e-22 79.9 8.5 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CBFNT PF08143.11 KFX97281.1 - 5.6 8.5 7.7 0.72 11.3 1.0 2.4 3 0 0 3 3 3 0 CBFNT (NUC161) domain Sel1 PF08238.12 KFX97282.1 - 5.7e-37 125.3 24.7 5.3e-08 33.3 0.1 7.7 7 0 0 7 7 7 6 Sel1 repeat Hce2 PF14856.6 KFX97282.1 - 2.1e-13 50.4 0.0 4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor ANAPC3 PF12895.7 KFX97282.1 - 0.13 12.5 2.0 15 5.9 0.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFX97282.1 - 2.2 9.1 7.0 37 5.3 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CBP4 PF07960.11 KFX97283.1 - 2.9e-27 95.1 0.5 3.5e-27 94.8 0.5 1.0 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.22 KFX97283.1 - 0.19 12.0 6.9 0.37 11.0 6.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L24e PF01246.20 KFX97284.1 - 4.1e-28 97.4 0.4 9.9e-28 96.2 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e AdoMet_MTase PF07757.13 KFX97285.1 - 9e-40 135.5 0.0 1.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KFX97285.1 - 0.0034 17.4 0.0 0.0074 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97285.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAC PF01849.18 KFX97286.1 - 2.1e-22 78.8 0.3 3.7e-22 78.0 0.3 1.4 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.13 KFX97287.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1687 PF07955.11 KFX97288.1 - 8.2e-31 107.1 0.1 1e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) 5_nucleotid_C PF02872.18 KFX97289.1 - 0.0038 17.5 0.0 0.014 15.7 0.0 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain RRM_1 PF00076.22 KFX97289.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAT PF04768.13 KFX97290.1 - 1.7e-52 177.5 0.6 3.2e-52 176.6 0.2 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KFX97290.1 - 6.7e-31 107.7 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KFX97290.1 - 2.2e-30 105.6 0.0 5.1e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX97290.1 - 0.08 13.1 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Arm PF00514.23 KFX97290.1 - 0.16 12.1 0.2 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Synaptobrevin PF00957.21 KFX97291.1 - 3e-27 94.2 1.1 3.6e-27 94.0 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.24 KFX97291.1 - 0.03 14.3 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF2207 PF09972.9 KFX97291.1 - 0.037 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3618 PF12277.8 KFX97291.1 - 0.051 13.8 0.4 0.37 11.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3618) Fzo_mitofusin PF04799.13 KFX97291.1 - 0.093 12.3 1.4 0.1 12.2 0.8 1.4 1 1 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.9 KFX97291.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KFX97291.1 - 4.4 7.6 11.1 5.1 7.4 5.3 2.4 2 1 0 2 2 2 0 Haemolysin XhlA Glyco_hydro_76 PF03663.14 KFX97292.1 - 4e-161 536.6 15.1 4.7e-161 536.4 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ATP-synt_Z PF16594.5 KFX97293.1 - 8.3 6.0 9.0 0.36 10.3 2.5 2.1 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated MFS_1 PF07690.16 KFX97294.1 - 1.3e-36 126.3 52.8 6.1e-31 107.6 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97294.1 - 1.7e-08 33.8 1.1 1.7e-08 33.8 1.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFX97294.1 - 4.9e-06 25.6 0.0 4.9e-06 25.6 0.0 2.2 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 KFX97294.1 - 0.0029 16.2 9.8 0.0033 16.1 2.8 3.4 2 2 2 4 4 4 1 MFS/sugar transport protein TRI12 PF06609.13 KFX97294.1 - 0.015 13.8 1.1 0.02 13.3 0.3 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KFX97294.1 - 0.045 14.0 1.4 0.6 10.4 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_3 PF05977.13 KFX97294.1 - 0.14 10.5 10.4 0.29 9.5 1.3 3.1 3 0 0 3 3 3 0 Transmembrane secretion effector Cupin_1 PF00190.22 KFX97295.1 - 9e-20 70.8 0.5 1.3e-19 70.2 0.5 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFX97295.1 - 0.00048 19.8 0.1 0.00083 19.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MARVEL PF01284.23 KFX97296.1 - 0.0018 18.3 14.5 0.05 13.6 14.1 2.1 1 1 1 2 2 2 2 Membrane-associating domain YscK PF06578.12 KFX97296.1 - 0.0063 16.1 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) MgtE PF01769.16 KFX97296.1 - 5.9 7.3 13.7 5.2 7.5 2.9 2.3 1 1 1 2 2 2 0 Divalent cation transporter Glyoxalase PF00903.25 KFX97297.1 - 0.00051 20.2 0.3 0.0014 18.8 0.3 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_2 PF02230.16 KFX97308.1 - 2.3e-57 194.3 0.0 4.2e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LigB PF02900.18 KFX97308.1 - 6.5e-34 117.2 0.0 1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DLH PF01738.18 KFX97308.1 - 2.4e-05 24.0 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KFX97308.1 - 9.8e-05 21.9 0.4 0.016 14.7 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KFX97308.1 - 0.00033 20.4 0.0 0.00074 19.2 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KFX97308.1 - 0.0038 16.5 0.2 4.2 6.6 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFX97308.1 - 0.053 13.4 0.1 6 6.7 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFX97308.1 - 0.13 11.9 1.1 0.58 9.8 0.2 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFX97308.1 - 0.23 10.6 0.0 5.9 6.0 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) MIT PF04212.18 KFX97309.1 - 3e-19 68.9 6.0 8.2e-19 67.4 6.0 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FAD_binding_4 PF01565.23 KFX97309.1 - 2.6e-14 53.2 0.0 6.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KFX97309.1 - 3e-07 30.3 0.0 7.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Helo_like_N PF17111.5 KFX97309.1 - 7.3e-05 22.2 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins adh_short PF00106.25 KFX97310.1 - 3.4e-34 118.0 0.1 3.3e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97310.1 - 7.5e-23 81.3 0.0 1.5e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97310.1 - 4.6e-08 33.2 0.0 7.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1521 PF07481.11 KFX97310.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Adeno_100 PF02438.16 KFX97310.1 - 0.052 11.7 0.0 0.067 11.4 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein Epimerase PF01370.21 KFX97310.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX97310.1 - 0.089 12.7 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding CDC48_N PF02359.18 KFX97310.1 - 0.09 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain GDP_Man_Dehyd PF16363.5 KFX97310.1 - 0.16 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 KFX97311.1 - 2.2e-14 53.1 0.2 4.7e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX97311.1 - 5e-06 26.5 12.3 9.3e-06 25.7 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX97312.1 - 1.9e-29 102.5 0.4 2.4e-29 102.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97312.1 - 9.7e-22 77.7 0.2 3.2e-21 76.0 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97312.1 - 4.8e-15 55.9 0.2 7.8e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX97312.1 - 3.4e-06 26.4 0.1 4.1e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX97312.1 - 0.00013 21.6 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX97312.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_2 PF07992.14 KFX97312.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KFX97313.1 - 1.2e-06 28.6 11.7 1.2e-06 28.6 11.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFX97313.1 - 0.0039 17.6 1.5 0.0089 16.4 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFX97313.1 - 0.042 14.1 0.2 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AA_permease_2 PF13520.6 KFX97318.1 - 4e-60 203.8 50.2 5.1e-60 203.5 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX97318.1 - 1.7e-16 59.9 40.8 2.4e-16 59.4 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1980 PF09323.10 KFX97318.1 - 0.023 14.6 1.8 0.28 11.1 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Na_Ca_ex PF01699.24 KFX97319.1 - 7.7e-32 110.3 32.5 5.5e-16 58.9 10.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CVNH PF08881.10 KFX97320.1 - 2.6e-10 40.9 0.8 1.8e-09 38.2 0.7 1.9 1 1 0 1 1 1 1 CVNH domain NPP1 PF05630.11 KFX97321.1 - 1.1e-45 156.2 0.6 6.1e-45 153.8 0.4 1.9 2 0 0 2 2 2 1 Necrosis inducing protein (NPP1) CAP_N PF01213.19 KFX97321.1 - 4.4 6.7 14.4 0.38 10.2 8.9 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sedlin_N PF04628.13 KFX97323.1 - 4e-38 130.5 0.0 6.3e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Thiamine_BP PF01910.17 KFX97323.1 - 1.6e-26 92.1 0.2 2.6e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Thiamine-binding protein L31 PF09784.9 KFX97324.1 - 3e-44 149.6 2.5 3.3e-44 149.5 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 YpzI PF14140.6 KFX97324.1 - 0.046 13.5 2.3 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 YpzI-like protein RRM_1 PF00076.22 KFX97325.1 - 1.5e-14 53.5 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_TPR_like PF17004.5 KFX97326.1 - 1.2e-31 109.1 1.7 4e-30 104.2 1.0 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KFX97326.1 - 5.8e-13 49.1 7.5 5.8e-13 49.1 7.5 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Nup88 PF10168.9 KFX97326.1 - 7.3e-05 20.8 3.6 0.026 12.3 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component TPR_19 PF14559.6 KFX97326.1 - 0.00022 21.7 12.3 0.16 12.5 1.4 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat GGA_N-GAT PF18308.1 KFX97326.1 - 0.00043 19.8 2.7 0.32 10.6 0.1 3.5 3 0 0 3 3 3 2 GGA N-GAT domain ANAPC3 PF12895.7 KFX97326.1 - 0.001 19.3 1.3 0.19 11.9 0.1 3.4 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KFX97326.1 - 0.011 15.8 1.7 16 5.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97326.1 - 0.042 14.1 0.1 6.3 7.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3BP5 PF05276.14 KFX97326.1 - 0.07 12.9 1.3 0.19 11.5 0.3 2.0 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Seryl_tRNA_N PF02403.22 KFX97326.1 - 0.086 13.1 4.3 0.61 10.4 4.3 2.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CNP1 PF08750.11 KFX97326.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 CNP1-like family BTAD PF03704.17 KFX97326.1 - 0.13 12.7 5.6 0.037 14.4 0.6 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain THOC7 PF05615.13 KFX97326.1 - 0.25 11.6 3.0 0.94 9.8 3.0 2.0 1 0 0 1 1 1 0 Tho complex subunit 7 CTK3_C PF12350.8 KFX97326.1 - 0.34 11.1 4.0 14 5.9 4.0 2.7 1 1 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus TPR_12 PF13424.6 KFX97326.1 - 1.2 9.4 4.2 16 5.9 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97326.1 - 2.9 9.0 11.8 1.1e+02 4.0 1.3 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 KFX97327.1 - 5.1e-38 130.3 0.3 8.3e-38 129.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Epimerase PF01370.21 KFX97329.1 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX97329.1 - 3.2e-09 36.3 0.0 4e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KFX97329.1 - 2.7e-08 33.2 0.0 7.2e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX97329.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX97329.1 - 0.0087 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KFX97329.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KFX97329.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DEAD PF00270.29 KFX97330.1 - 4.9e-41 140.4 1.6 7.6e-41 139.8 1.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX97330.1 - 2.8e-32 111.3 0.0 1.9e-30 105.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97330.1 - 1e-07 32.1 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M19 PF01244.21 KFX97330.1 - 0.009 15.2 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RdRP PF05183.12 KFX97331.1 - 8.1e-129 430.9 0.0 1.1e-128 430.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase peroxidase PF00141.23 KFX97332.1 - 1.4e-46 159.1 0.0 1.9e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.25 KFX97333.1 - 4.3e-17 62.3 0.0 7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFX97333.1 - 0.0034 18.0 0.7 0.0092 16.6 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Integrin_alpha PF00357.20 KFX97333.1 - 3.2 7.9 4.8 29 5.0 0.3 2.8 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region CENP-B_dimeris PF09026.10 KFX97335.1 - 0.00081 19.7 3.2 0.00081 19.7 3.2 1.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Radial_spoke PF04712.12 KFX97335.1 - 0.02 13.9 1.1 0.51 9.2 2.4 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein DUF2254 PF10011.9 KFX97335.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) FAM176 PF14851.6 KFX97335.1 - 0.078 12.6 1.1 0.13 11.9 1.1 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KFX97335.1 - 0.26 10.6 4.9 0.4 9.9 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KFX97335.1 - 0.28 9.3 4.6 0.38 8.8 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mito_carr PF00153.27 KFX97336.1 - 1.7e-65 217.0 2.8 1.5e-23 82.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX97336.1 - 0.05 12.8 1.6 4.3 6.4 0.0 3.4 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Dna2 PF08696.11 KFX97337.1 - 6e-70 235.2 0.2 1.5e-69 233.9 0.2 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFX97337.1 - 3.3e-51 173.8 0.0 5.8e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX97337.1 - 2.2e-32 112.9 0.4 1.9e-16 60.6 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX97337.1 - 1.3e-14 54.4 0.0 2.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX97337.1 - 6.9e-13 49.2 0.0 1.6e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KFX97337.1 - 1.2e-08 35.2 0.2 1.4e-07 31.7 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KFX97337.1 - 3.3e-06 27.0 1.3 0.38 10.5 0.0 4.0 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KFX97337.1 - 0.00033 19.9 0.0 0.00077 18.7 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase Helicase_RecD PF05127.14 KFX97337.1 - 0.00035 20.5 0.0 0.00098 19.0 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KFX97337.1 - 0.00039 20.1 0.1 0.00094 18.8 0.1 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KFX97337.1 - 0.00044 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 KFX97337.1 - 0.0008 19.1 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Csa1 PF06023.12 KFX97337.1 - 0.0022 17.4 0.1 0.01 15.2 0.1 1.8 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 CbiA PF01656.23 KFX97337.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KFX97337.1 - 0.015 14.8 0.0 0.35 10.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KFX97337.1 - 0.023 15.2 0.1 0.59 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX97337.1 - 0.026 14.0 0.1 0.064 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KFX97337.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 KFX97337.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFX97337.1 - 0.063 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MeaB PF03308.16 KFX97337.1 - 0.081 11.9 0.0 0.22 10.5 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UvrD_C_2 PF13538.6 KFX97337.1 - 0.081 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF87 PF01935.17 KFX97337.1 - 0.081 13.0 2.8 0.13 12.3 0.3 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KFX97337.1 - 0.082 12.8 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 KFX97337.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Aldo_ket_red PF00248.21 KFX97338.1 - 6.1e-55 186.5 0.0 7.5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GTP_EFTU PF00009.27 KFX97339.1 - 2.8e-18 66.2 0.0 5.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFX97339.1 - 4.8e-08 33.3 0.7 1.3e-07 31.8 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KFX97339.1 - 0.00019 21.7 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFX97339.1 - 0.0012 18.9 0.2 0.0049 17.0 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX97339.1 - 0.019 14.9 0.2 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KFX97339.1 - 0.024 14.4 0.4 1.5 8.6 0.0 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation LSM PF01423.22 KFX97340.1 - 1.5e-18 66.2 0.1 1.8e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.17 KFX97341.1 - 6.5e-26 91.5 0.0 1.2e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Abhydrolase_1 PF00561.20 KFX97361.1 - 1.5e-22 80.5 0.1 1e-21 77.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFX97361.1 - 5.6e-22 77.1 0.0 1.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KFX97361.1 - 0.00012 21.4 0.0 0.013 14.8 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KFX97361.1 - 0.00042 20.0 0.0 0.025 14.2 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) RRM_1 PF00076.22 KFX97362.1 - 3.3e-14 52.4 0.0 1.1e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX97362.1 - 0.0032 17.4 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4646 PF15496.6 KFX97362.1 - 0.067 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) DUF2457 PF10446.9 KFX97362.1 - 5.8 5.9 10.8 0.13 11.4 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Methyltransf_3 PF01596.17 KFX97363.1 - 4e-35 120.9 0.0 6.3e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 KFX97363.1 - 1.5e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX97363.1 - 1.9e-11 44.1 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KFX97363.1 - 2.5e-11 44.5 0.0 2.3e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97363.1 - 1.3e-08 35.5 0.0 2.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFX97363.1 - 6.3e-05 22.8 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KFX97363.1 - 0.00023 20.6 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 KFX97363.1 - 0.0025 17.5 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 KFX97363.1 - 0.006 17.3 0.0 0.015 16.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.17 KFX97363.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 KFX97363.1 - 0.039 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_30 PF05430.11 KFX97363.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase ISN1 PF06437.11 KFX97364.1 - 6.2e-196 651.2 0.0 7e-196 651.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pex16 PF08610.10 KFX97365.1 - 1.5e-130 435.1 0.1 2e-130 434.7 0.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.20 KFX97365.1 - 0.014 16.0 0.6 5.3 7.7 0.1 2.3 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus MFS_1 PF07690.16 KFX97366.1 - 1.3e-39 136.1 39.6 3.3e-38 131.5 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97366.1 - 2.9e-07 29.7 3.9 2.9e-07 29.7 3.9 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KFX97366.1 - 3.8e-05 22.8 1.5 6.9e-05 21.9 1.5 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX97366.1 - 5.6e-05 22.2 0.0 0.00027 19.9 0.0 2.6 1 1 0 1 1 1 1 MFS_1 like family F-box PF00646.33 KFX97367.1 - 1.7e-07 30.9 1.0 3.4e-07 30.0 1.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX97367.1 - 8.1e-05 22.4 1.0 0.00015 21.6 1.0 1.5 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.23 KFX97368.1 - 2.1e-58 197.7 0.1 3.7e-58 196.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX97368.1 - 1.3e-13 51.3 0.0 3.4e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BAR PF03114.18 KFX97368.1 - 3.4e-13 49.8 0.2 9.4e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFX97368.1 - 1.4e-12 47.3 0.2 2.9e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX97368.1 - 7.9e-12 44.6 0.1 1.6e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX97368.1 - 2.2e-09 36.9 0.0 4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4_3 PF13920.6 KFX97368.1 - 2.9e-07 30.2 3.0 5.4e-07 29.4 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97368.1 - 6.3e-07 29.3 3.7 1.6e-06 28.0 3.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 KFX97368.1 - 9.8e-07 28.9 0.0 2.9e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KFX97368.1 - 1.2e-06 28.2 5.5 2.8e-06 27.1 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX97368.1 - 1.5e-05 24.7 8.5 7.1e-05 22.6 8.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX97368.1 - 2.6e-05 24.5 5.1 4.7e-05 23.6 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX97368.1 - 0.0002 21.3 3.9 0.00038 20.4 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX97368.1 - 0.0079 16.3 7.1 0.018 15.2 7.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Fer2 PF00111.27 KFX97368.1 - 0.065 13.2 0.7 0.18 11.8 0.7 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain EVC2_like PF12297.8 KFX97368.1 - 0.15 10.7 1.6 0.17 10.5 0.1 1.7 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Prok-RING_4 PF14447.6 KFX97368.1 - 0.2 11.5 5.6 0.62 10.0 5.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFX97368.1 - 0.23 11.3 3.6 0.51 10.2 3.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4449 PF14613.6 KFX97369.1 - 1.9e-09 37.8 3.9 2e-08 34.5 0.3 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KFX97369.1 - 0.00081 19.4 0.1 0.0038 17.2 0.0 2.2 2 0 0 2 2 2 1 Tricorn protease C1 domain CPSase_L_D2 PF02786.17 KFX97370.1 - 1.7e-73 246.6 0.0 2.7e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain bVLRF1 PF18826.1 KFX97370.1 - 3.8e-62 208.6 0.2 7.2e-62 207.7 0.2 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Biotin_carb_C PF02785.19 KFX97370.1 - 4.2e-36 123.3 0.0 8.5e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFX97370.1 - 8.1e-36 122.9 0.0 1.9e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFX97370.1 - 1.3e-13 50.6 0.5 5.3e-13 48.6 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX97370.1 - 5.8e-09 35.8 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX97370.1 - 7.6e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX97370.1 - 0.00092 19.0 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KFX97370.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Ank_5 PF13857.6 KFX97370.1 - 0.033 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RimK PF08443.11 KFX97370.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFX97370.1 - 0.18 11.7 0.1 4.3 7.2 0.0 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like Mito_carr PF00153.27 KFX97372.1 - 2e-43 146.2 6.9 1.6e-17 63.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR_2 PF13233.6 KFX97375.1 - 0.0005 20.8 0.1 0.00065 20.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.23 KFX97376.1 - 3.1e-19 69.3 0.6 6.5e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX97376.1 - 9.2e-12 45.3 0.0 2.4e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX97376.1 - 1.3e-08 35.0 0.0 3.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFX97376.1 - 9e-06 25.6 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX97376.1 - 0.00086 19.6 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFX97376.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KFX97376.1 - 0.033 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 KaiC PEPCK_ATP PF01293.20 KFX97378.1 - 5e-43 147.4 0.0 5.8e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF1996 PF09362.10 KFX97382.1 - 3e-39 135.4 0.0 3.3e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AICARFT_IMPCHas PF01808.18 KFX97386.1 - 5.4e-51 173.8 0.0 8.1e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Glyco_hydro_18 PF00704.28 KFX97388.1 - 2.2e-50 172.2 0.2 3.8e-50 171.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX97388.1 - 3.2e-05 23.9 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 KFX97389.1 - 8.4e-09 35.4 0.1 0.007 16.4 0.0 3.9 4 0 0 4 4 4 3 LysM domain PAN_4 PF14295.6 KFX97389.1 - 1.4e-08 34.5 3.0 0.0029 17.5 0.2 3.2 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 KFX97389.1 - 4.1e-05 23.3 1.4 0.34 10.8 0.1 2.8 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.11 KFX97389.1 - 0.0077 16.3 4.7 1.6 8.9 0.5 2.9 2 0 0 2 2 2 2 PAN-like domain Aldo_ket_red PF00248.21 KFX97394.1 - 4.4e-52 177.1 0.0 1.8e-51 175.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Podoplanin PF05808.11 KFX97395.1 - 0.02 15.0 2.4 0.047 13.8 2.4 1.6 1 0 0 1 1 1 0 Podoplanin Glycophorin_A PF01102.18 KFX97395.1 - 0.047 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A TMEM51 PF15345.6 KFX97395.1 - 0.093 12.6 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 CCER1 PF15482.6 KFX97395.1 - 0.3 10.9 6.8 0.64 9.9 0.3 2.4 3 0 0 3 3 3 0 Coiled-coil domain-containing glutamate-rich protein family 1 RGS PF00615.19 KFX97399.1 - 2.7e-33 114.7 0.0 5.7e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFX97399.1 - 6.7e-21 74.1 0.0 5.1e-17 61.7 0.0 3.2 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf_PR_Knuckle PF18445.1 KFX97399.1 - 9.5e-05 22.1 0.1 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 PR zinc knuckle motif TruB_N PF01509.18 KFX97402.1 - 0.14 12.6 0.1 0.57 10.5 0.0 2.1 2 0 0 2 2 2 0 TruB family pseudouridylate synthase (N terminal domain) PIG-X PF08320.12 KFX97403.1 - 6.6e-51 173.2 0.0 2e-50 171.7 0.0 1.8 2 0 0 2 2 2 1 PIG-X / PBN1 RSN1_7TM PF02714.15 KFX97411.1 - 3.4e-83 279.1 23.3 3.4e-83 279.1 23.3 2.1 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFX97411.1 - 1.5e-43 148.3 0.0 1.5e-43 148.3 0.0 3.7 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFX97411.1 - 2.5e-27 96.3 0.4 4.8e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFX97411.1 - 3e-15 56.1 0.0 7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PA26 PF04636.13 KFX97414.1 - 0.031 13.2 0.5 0.05 12.5 0.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5580 PF17743.1 KFX97414.1 - 0.85 8.1 7.3 0.39 9.2 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5580) Peptidase_S49_N PF08496.10 KFX97414.1 - 1.9 8.6 11.8 3.5 7.7 11.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SKN1 PF03935.15 KFX97415.1 - 1.8e-225 749.1 0.3 2.1e-225 748.9 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CHD5 PF04420.14 KFX97417.1 - 8.2e-15 55.0 0.2 1.3e-14 54.4 0.2 1.3 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 KFX97418.1 - 1.9e-06 27.4 14.5 0.0019 17.9 0.8 4.2 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat Asp PF00026.23 KFX97420.1 - 2.4e-67 227.6 3.3 3e-67 227.3 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX97420.1 - 2.2e-08 34.6 5.0 2.4e-07 31.2 0.3 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX97420.1 - 6.1e-05 23.6 0.1 0.81 10.4 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KFX97420.1 - 0.00085 19.8 0.1 0.72 10.5 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KFX97420.1 - 0.0095 15.7 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal RRM_1 PF00076.22 KFX97421.1 - 3e-13 49.4 0.0 1e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX97421.1 - 0.0031 17.5 0.1 0.0085 16.1 0.1 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SMN PF06003.12 KFX97422.1 - 2.1e-08 33.8 1.0 0.00016 21.0 0.1 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) Copper-bind PF00127.20 KFX97423.1 - 0.0064 16.9 0.5 0.018 15.5 0.5 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KFX97423.1 - 0.01 15.8 0.4 0.048 13.7 0.4 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Syndecan PF01034.20 KFX97424.1 - 0.18 11.8 0.4 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Syndecan domain DUF4282 PF14110.6 KFX97424.1 - 4.8 8.0 12.3 15 6.4 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Ecl1 PF12855.7 KFX97431.1 - 4.3e-20 73.6 7.5 5.2e-20 73.3 7.5 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 KFX97431.1 - 0.14 11.9 2.0 0.27 11.0 2.0 1.4 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 KFX97431.1 - 0.24 10.9 5.4 2.8 7.5 5.4 2.2 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DNA_pol_lambd_f PF10391.9 KFX97432.1 - 8.9e-21 73.5 0.4 1.9e-20 72.4 0.4 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFX97432.1 - 1.2e-19 70.2 1.6 1.3e-19 70.1 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KFX97432.1 - 2.9e-19 69.3 0.0 5.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KFX97432.1 - 4.1e-08 33.5 0.0 8.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFX97432.1 - 0.11 13.2 0.0 0.78 10.4 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain BRCT_2 PF16589.5 KFX97432.1 - 0.15 12.5 0.0 0.51 10.8 0.0 1.9 1 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Sacchrp_dh_NADP PF03435.18 KFX97433.1 - 2.7e-14 53.5 0.0 4.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFX97433.1 - 0.065 13.3 0.0 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.19 KFX97434.1 - 3.4e-40 136.0 9.3 3.8e-40 135.8 9.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KFX97434.1 - 0.0013 18.7 3.0 0.0021 18.0 3.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 KFX97434.1 - 0.0029 17.7 0.8 0.004 17.2 0.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain zf-RING_13 PF17977.1 KFX97434.1 - 0.0035 17.5 1.7 0.0049 17.0 1.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KFX97434.1 - 0.018 15.1 4.4 0.1 12.6 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Sgf11 PF08209.11 KFX97434.1 - 0.047 13.3 0.3 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.10 KFX97434.1 - 0.047 13.8 0.6 0.099 12.8 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KFX97434.1 - 0.16 11.7 1.6 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_ribbon_SprT PF17283.2 KFX97434.1 - 0.19 11.6 4.3 0.22 11.4 3.1 1.7 1 1 1 2 2 2 0 SprT-like zinc ribbon domain CarbpepA_inh PF02977.15 KFX97434.1 - 0.25 11.1 0.3 0.25 11.1 0.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 KFX97434.1 - 0.61 10.6 6.1 1 9.9 0.5 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-rbx1 PF12678.7 KFX97435.1 - 3.4e-09 36.8 12.2 5.1e-08 33.1 2.5 2.9 3 0 0 3 3 2 2 RING-H2 zinc finger domain PHD PF00628.29 KFX97435.1 - 5e-09 35.9 8.2 5e-09 35.9 8.2 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KFX97435.1 - 5.1e-08 33.1 2.9 5.1e-08 33.1 2.9 4.0 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 KFX97435.1 - 9.3e-07 28.6 2.3 9.3e-07 28.6 2.3 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFX97435.1 - 2.8e-05 23.9 1.9 2.8e-05 23.9 1.9 4.1 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX97435.1 - 3.4e-05 23.6 0.9 3.4e-05 23.6 0.9 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX97435.1 - 3.6e-05 23.7 2.0 3.6e-05 23.7 2.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFX97435.1 - 5.2e-05 23.1 3.6 5.2e-05 23.1 3.6 3.5 4 0 0 4 4 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFX97435.1 - 5.4e-05 22.7 2.5 5.4e-05 22.7 2.5 2.9 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFX97435.1 - 0.00028 20.7 4.1 0.00028 20.7 4.1 3.6 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KFX97435.1 - 0.00056 19.4 2.6 0.00061 19.2 0.1 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger Prok-RING_1 PF14446.6 KFX97435.1 - 0.006 16.5 2.6 0.006 16.5 2.6 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFX97435.1 - 0.28 10.8 0.1 0.28 10.8 0.1 3.4 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 KFX97435.1 - 0.38 10.8 20.4 0.45 10.6 1.2 4.8 3 2 0 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.8 KFX97435.1 - 0.44 10.8 9.9 0.14 12.4 2.0 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KFX97435.1 - 0.88 9.8 5.4 0.26 11.5 0.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon like family PHD_2 PF13831.6 KFX97435.1 - 1.3 8.6 12.1 0.019 14.5 3.6 2.2 2 0 0 2 2 2 0 PHD-finger Pellino PF04710.14 KFX97435.1 - 1.5 7.4 4.7 0.75 8.4 0.7 2.0 1 1 1 2 2 2 0 Pellino zf-RING-like PF08746.11 KFX97435.1 - 2.1 8.7 12.3 0.067 13.5 1.8 2.6 2 0 0 2 2 2 0 RING-like domain Prim_Zn_Ribbon PF08273.12 KFX97435.1 - 4.9 7.5 8.5 2.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase MRP-L46 PF11788.8 KFX97436.1 - 1.3e-31 109.8 0.0 2.3e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KFX97436.1 - 2.3 8.3 4.9 1.2 9.2 0.1 2.5 1 1 1 2 2 2 0 NUDIX domain Arf PF00025.21 KFX97437.1 - 1.4e-14 54.0 0.0 6.6e-14 51.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFX97437.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PRCC PF10253.9 KFX97438.1 - 3.3e-37 129.3 4.0 3.3e-37 129.3 4.0 2.3 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DLIC PF05783.11 KFX97438.1 - 3.1 6.5 6.5 4.7 5.9 6.5 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CRIM PF16978.5 KFX97439.1 - 3.1e-43 147.3 0.0 5.6e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KFX97439.1 - 4.3e-31 107.4 0.0 8e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KFX97439.1 - 8.5e-05 22.7 0.1 0.00021 21.4 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KFX97439.1 - 0.033 14.3 0.1 0.076 13.1 0.1 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain PBP1_TM PF14812.6 KFX97439.1 - 0.11 12.9 13.4 0.24 11.8 1.3 3.6 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRP-alpha_N PF04086.13 KFX97439.1 - 0.34 10.8 10.1 0.79 9.6 10.1 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_hydro_28 PF00295.17 KFX97455.1 - 2e-53 181.5 1.8 2.6e-53 181.2 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ET PF01684.16 KFX97455.1 - 0.072 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 ET module ORC6 PF05460.13 KFX97457.1 - 3.2e-38 131.9 7.8 4.8e-32 111.6 0.9 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Cwf_Cwc_15 PF04889.12 KFX97457.1 - 0.031 14.0 2.0 0.044 13.5 2.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KFX97457.1 - 7.5 7.0 9.5 15 6.1 9.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 KFX97457.1 - 8 6.8 8.5 79 3.6 6.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) EF-hand_6 PF13405.6 KFX97458.1 - 4.4e-07 29.3 2.5 0.029 14.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFX97458.1 - 2.8e-06 27.7 2.0 0.0053 17.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFX97458.1 - 1.5e-05 24.3 0.7 3.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFX97458.1 - 3.2e-05 23.2 0.9 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFX97458.1 - 0.032 14.1 0.5 0.067 13.0 0.2 1.7 1 1 0 1 1 1 0 EF-hand domain pair Metallophos PF00149.28 KFX97459.1 - 7.5e-33 114.8 0.0 1.9e-28 100.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFX97459.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RNA_pol_Rpc4 PF05132.14 KFX97463.1 - 0.12 12.8 8.3 0.78 10.2 0.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 BUD22 PF09073.10 KFX97463.1 - 0.72 9.1 19.4 0.25 10.6 11.0 2.0 2 0 0 2 2 2 0 BUD22 DUF913 PF06025.12 KFX97463.1 - 2.4 7.1 6.5 8.4 5.3 2.4 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 KFX97463.1 - 3.8 7.3 14.0 6.1 6.6 9.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Pex14_N PF04695.13 KFX97463.1 - 9.5 6.9 13.9 0.4 11.3 5.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region JmjC PF02373.22 KFX97465.1 - 5.4e-40 136.4 0.3 1.4e-39 135.1 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFX97465.1 - 2.3e-18 66.3 3.6 4.1e-18 65.5 3.6 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFX97465.1 - 4.7e-15 55.6 2.1 1.1e-14 54.4 2.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KFX97465.1 - 1.8e-14 53.4 0.2 5.6e-14 51.8 0.2 1.9 1 0 0 1 1 1 1 jmjN domain CEBP_ZZ PF16366.5 KFX97465.1 - 0.61 10.4 3.9 1.8 8.9 3.9 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain WD40 PF00400.32 KFX97467.1 - 6.1e-14 52.2 14.1 0.00055 20.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFX97467.1 - 3.1 8.4 0.0 3.1 8.4 0.0 3.5 5 0 0 5 5 5 0 PQQ-like domain Mcl1_mid PF12341.8 KFX97468.1 - 8.7e-96 320.8 0.0 3.9e-95 318.6 0.0 2.0 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFX97468.1 - 1.7e-20 73.0 6.8 2e-07 31.6 0.2 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97468.1 - 4e-18 65.5 0.0 0.00041 20.6 0.0 6.9 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFX97468.1 - 4e-07 29.5 0.0 9.7e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KFX97468.1 - 0.00045 20.2 0.1 0.041 13.8 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFX97468.1 - 0.0052 14.9 0.0 0.013 13.5 0.0 1.6 1 1 0 1 1 1 1 IKI3 family Ge1_WD40 PF16529.5 KFX97468.1 - 0.033 13.1 0.0 9.4 5.1 0.0 3.2 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 KFX97468.1 - 0.11 12.6 3.4 0.27 11.3 3.4 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Ras PF00071.22 KFX97469.1 - 1.7e-65 219.6 0.5 2e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX97469.1 - 6.6e-36 123.2 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX97469.1 - 3e-16 59.4 0.1 3.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX97469.1 - 1.8e-05 24.8 0.1 9.6e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX97469.1 - 2.2e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFX97469.1 - 8.2e-05 22.2 0.4 0.00023 20.8 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFX97469.1 - 0.00026 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFX97469.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFX97469.1 - 0.00082 19.8 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFX97469.1 - 0.0042 16.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFX97469.1 - 0.0081 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX97469.1 - 0.036 14.4 0.0 0.067 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX97469.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KFX97469.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KFX97469.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 KFX97469.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KFX97469.1 - 0.076 13.5 0.1 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KFX97469.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFX97469.1 - 0.1 12.4 0.1 0.65 9.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KFX97469.1 - 0.12 11.9 0.1 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain XRN_M PF17846.1 KFX97475.1 - 1e-142 476.2 0.0 3.9e-142 474.3 0.0 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFX97475.1 - 3e-98 328.1 0.0 6.1e-98 327.1 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.19 KFX97475.1 - 1.5e-34 119.5 0.8 3.8e-22 79.0 0.1 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KFX97475.1 - 1.7e-08 34.7 0.1 4.6e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KFX97475.1 - 0.25 11.2 2.5 0.34 10.7 0.5 2.4 3 0 0 3 3 3 0 Cell morphogenesis C-terminal zf-CCHC PF00098.23 KFX97475.1 - 0.27 11.4 2.0 0.66 10.2 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFX97475.1 - 0.31 10.9 1.4 0.68 9.8 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle HEAT PF02985.22 KFX97475.1 - 0.77 10.2 3.3 22 5.6 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat Uso1_p115_head PF04869.14 KFX97476.1 - 7.2e-117 390.0 0.0 1.5e-116 389.0 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KFX97476.1 - 1.2e-15 58.0 24.5 1.2e-15 58.0 24.5 3.0 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 KFX97476.1 - 0.041 13.6 0.2 0.041 13.6 0.2 3.7 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Atx10homo_assoc PF09759.9 KFX97476.1 - 0.31 11.1 6.8 12 6.0 0.0 4.2 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Prominin PF05478.11 KFX97476.1 - 3.9 5.3 17.9 6.1 4.7 17.9 1.2 1 0 0 1 1 1 0 Prominin tRNA-synt_1 PF00133.22 KFX97477.1 - 1.9e-222 739.8 0.0 2.6e-222 739.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX97477.1 - 1.5e-22 80.2 0.0 5.6e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX97477.1 - 3.1e-15 55.8 0.1 5e-06 25.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFX97477.1 - 0.0086 15.5 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Rav1p_C PF12234.8 KFX97478.1 - 7e-282 936.6 0.4 9.6e-282 936.1 0.4 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.10 KFX97478.1 - 6.3e-123 411.3 70.4 6.3e-123 411.3 70.4 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein WD40 PF00400.32 KFX97478.1 - 0.05 14.5 3.0 42 5.2 0.0 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat OPT PF03169.15 KFX97479.1 - 3.8e-148 494.9 27.0 4.4e-148 494.7 27.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 KFX97479.1 - 0.34 10.9 2.3 0.7 9.9 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S Methyltransf_25 PF13649.6 KFX97480.1 - 3.4e-13 50.1 0.1 1.8e-12 47.8 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 KFX97480.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFX97480.1 - 1.6e-11 44.7 0.0 8.8e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97480.1 - 1.6e-10 41.0 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97480.1 - 7.9e-07 29.1 0.0 4.7e-06 26.5 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFX97480.1 - 1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX97480.1 - 8.3e-06 25.4 0.1 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFX97480.1 - 3.5e-05 23.3 0.1 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFX97480.1 - 0.00084 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 KFX97480.1 - 0.00092 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KFX97480.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KFX97480.1 - 0.0017 19.1 0.0 0.0045 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX97480.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KFX97480.1 - 0.0038 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KFX97480.1 - 0.0049 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFX97480.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KFX97480.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFX97480.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 KFX97480.1 - 0.089 13.8 0.0 0.47 11.5 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain WD40_alt PF14077.6 KFX97480.1 - 0.13 12.2 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Mo25 PF08569.11 KFX97481.1 - 4e-129 430.7 0.0 5.8e-129 430.2 0.0 1.2 1 0 0 1 1 1 1 Mo25-like SWIB PF02201.18 KFX97481.1 - 1.3e-20 73.0 0.0 3.2e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain CENP-B_dimeris PF09026.10 KFX97481.1 - 0.11 12.9 6.3 0.25 11.8 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KFX97481.1 - 0.69 9.6 3.4 1.7 8.3 3.4 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KFX97481.1 - 1.1 8.6 8.6 1.7 7.9 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KFX97481.1 - 3.9 7.9 10.3 0.25 11.8 4.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ANAPC_CDC26 PF10471.9 KFX97483.1 - 0.07 14.0 0.3 0.27 12.1 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Pkinase PF00069.25 KFX97484.1 - 6.2e-67 225.7 0.0 8.2e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97484.1 - 3.3e-33 115.1 0.0 1.3e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX97484.1 - 0.00028 20.3 0.1 0.0087 15.4 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFX97484.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX97484.1 - 0.0081 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family BES1_N PF05687.13 KFX97484.1 - 0.0097 16.3 1.6 0.0097 16.3 1.6 2.3 3 0 0 3 3 3 1 BES1/BZR1 plant transcription factor, N-terminal Haspin_kinase PF12330.8 KFX97484.1 - 0.022 13.7 0.1 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFX97484.1 - 0.041 13.5 0.2 2.1 7.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rif1_N PF12231.8 KFX97486.1 - 4.8e-132 440.5 0.0 7e-132 439.9 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Nrap PF03813.14 KFX97499.1 - 0.7 9.9 2.7 5.5 7.0 0.8 2.0 1 1 1 2 2 2 0 Nrap protein domain 1 RPN7 PF10602.9 KFX97500.1 - 1.3e-58 197.5 0.4 2e-58 196.9 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFX97500.1 - 2e-13 50.8 0.0 4.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain VirionAssem_T7 PF11653.8 KFX97500.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Lactamase_B_2 PF12706.7 KFX97502.1 - 9e-25 87.4 0.4 4.7e-22 78.5 0.4 3.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFX97502.1 - 0.00033 20.7 0.5 0.0009 19.3 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KFX97502.1 - 0.051 13.5 0.1 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Prok-JAB PF14464.6 KFX97502.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Fungal_trans PF04082.18 KFX97510.1 - 8.3e-13 48.0 0.1 1.5e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KFX97511.1 - 1e-81 273.3 55.4 2.5e-46 157.7 22.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX97511.1 - 1.6e-40 138.8 0.0 4.1e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX97511.1 - 1.1e-22 79.7 9.7 1.2e-22 79.6 0.1 3.4 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 KFX97511.1 - 2.8e-06 26.7 41.2 2.2e-05 23.7 16.2 3.0 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KFX97511.1 - 1.1e-05 25.9 0.1 0.029 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KFX97511.1 - 2.2e-05 25.0 0.2 5.7e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KFX97511.1 - 0.0002 21.6 0.6 1.1 9.6 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFX97511.1 - 0.0006 19.4 0.2 0.018 14.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX97511.1 - 0.00071 19.3 0.5 0.09 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX97511.1 - 0.00079 19.4 0.1 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 KFX97511.1 - 0.003 17.8 0.5 0.92 9.7 0.2 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFX97511.1 - 0.0041 16.7 1.0 1.6 8.3 0.4 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFX97511.1 - 0.0058 16.8 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX97511.1 - 0.0089 16.6 0.0 5.7 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX97511.1 - 0.012 15.5 0.2 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KFX97511.1 - 0.049 13.3 0.7 6.6 6.4 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KFX97511.1 - 0.065 13.7 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KFX97511.1 - 0.081 12.3 0.0 0.68 9.2 0.0 2.4 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KFX97511.1 - 0.083 12.6 0.7 8.9 6.0 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFX97511.1 - 0.15 11.9 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KFX97511.1 - 0.15 12.2 0.2 28 4.8 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Sec8_exocyst PF04048.14 KFX97512.1 - 1.5e-47 161.1 2.4 2.9e-47 160.1 2.4 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KFX97512.1 - 1.4e-10 40.9 3.3 3e-10 39.9 3.3 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KFX97512.1 - 0.009 14.6 1.1 0.018 13.7 1.1 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 COG2 PF06148.11 KFX97512.1 - 0.014 15.5 2.4 0.015 15.4 0.3 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HIP1_clath_bdg PF16515.5 KFX97512.1 - 0.044 14.4 1.1 0.13 12.9 1.1 1.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uso1_p115_C PF04871.13 KFX97512.1 - 0.044 14.1 0.9 0.099 13.0 0.9 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Exonuc_VII_L PF02601.15 KFX97512.1 - 0.19 11.3 3.6 0.38 10.3 3.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vps51 PF08700.11 KFX97512.1 - 0.2 11.7 1.6 0.54 10.4 0.5 2.3 2 0 0 2 2 2 0 Vps51/Vps67 FliJ PF02050.16 KFX97512.1 - 0.36 11.0 2.9 0.92 9.7 2.9 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein SMI1_KNR4 PF09346.10 KFX97513.1 - 5.3e-34 117.5 0.0 1e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.11 KFX97514.1 - 2.7e-66 222.2 3.2 3e-66 222.0 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PQQ_3 PF13570.6 KFX97514.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 PQQ-like domain RF-1 PF00472.20 KFX97515.1 - 6.1e-23 81.0 0.7 8.5e-23 80.5 0.7 1.2 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 KFX97516.1 - 3.4e-10 39.4 8.7 8.3e-07 28.5 2.0 2.2 1 1 1 2 2 2 2 Small subunit of serine palmitoyltransferase-like CENP-I PF07778.11 KFX97517.1 - 6.8e-25 87.8 0.0 8.6e-13 47.8 0.0 2.6 2 1 0 2 2 2 2 Mis6 Sacchrp_dh_C PF16653.5 KFX97519.1 - 6.8e-97 324.7 0.0 1.3e-96 323.8 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KFX97519.1 - 4.3e-26 91.7 2.0 7e-26 91.0 2.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFX97519.1 - 1.5e-08 34.8 0.2 2.6e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KFX97519.1 - 0.0004 20.0 2.7 0.00092 18.8 1.2 2.4 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 KFX97519.1 - 0.00069 19.6 3.4 0.0013 18.6 3.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KFX97519.1 - 0.0091 16.8 0.3 0.017 15.9 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFX97519.1 - 0.011 16.3 1.5 0.02 15.6 1.5 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFX97519.1 - 0.12 12.9 0.4 0.22 12.0 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TRAPPC9-Trs120 PF08626.11 KFX97521.1 - 0 1454.1 0.0 0 1453.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 KFX97521.1 - 0.0089 16.2 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MMM1 PF10296.9 KFX97522.1 - 2.9e-141 470.3 0.0 2.5e-140 467.2 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 CDC27 PF09507.10 KFX97522.1 - 0.74 9.1 5.5 1.1 8.6 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDP-OH_P_transf PF01066.21 KFX97523.1 - 2.3e-14 53.9 0.9 2.3e-14 53.9 0.9 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tyr-DNA_phospho PF06087.12 KFX97524.1 - 7.6e-88 295.2 0.0 9.4e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KFX97524.1 - 0.00019 21.1 2.7 0.00019 21.1 2.7 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KFX97524.1 - 0.0033 17.3 0.0 0.081 12.8 0.0 2.6 3 0 0 3 3 3 1 PLD-like domain Gram_pos_anchor PF00746.21 KFX97524.1 - 0.014 15.3 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif IPPT PF01715.17 KFX97525.1 - 3.7e-66 223.2 0.1 5.1e-66 222.7 0.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KFX97525.1 - 0.00014 21.4 0.1 0.00032 20.2 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 KFX97525.1 - 0.00019 21.7 0.1 0.00036 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_33 PF13671.6 KFX97525.1 - 0.0019 18.4 0.1 0.08 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 KFX97525.1 - 0.016 15.5 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.27 KFX97525.1 - 0.019 15.5 0.0 0.051 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KFX97525.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFX97525.1 - 0.051 14.1 0.1 0.9 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KFX97525.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KFX97525.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Pex2_Pex12 PF04757.14 KFX97525.1 - 0.092 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region AKAP95 PF04988.12 KFX97525.1 - 0.094 12.9 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Hydin_ADK PF17213.3 KFX97525.1 - 0.14 12.4 0.2 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SecY PF00344.20 KFX97526.1 - 1.8e-71 241.0 9.9 2.2e-71 240.6 9.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFX97526.1 - 1.9e-17 62.8 0.3 6e-17 61.2 0.3 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ABC_membrane PF00664.23 KFX97527.1 - 2.5e-55 188.1 25.0 3.2e-35 122.1 6.1 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX97527.1 - 1.6e-50 171.2 0.0 1.4e-28 100.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX97527.1 - 1.4e-08 34.4 0.1 0.0022 17.5 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX97527.1 - 8.5e-07 29.7 0.2 0.0015 19.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFX97527.1 - 4.3e-06 26.8 0.5 0.11 12.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX97527.1 - 2.2e-05 24.4 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX97527.1 - 2.9e-05 24.1 0.6 0.066 13.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KFX97527.1 - 0.00014 22.1 0.0 5.4 7.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFX97527.1 - 0.00022 20.9 0.3 0.4 10.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KFX97527.1 - 0.00057 20.0 1.2 0.036 14.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KFX97527.1 - 0.0015 18.9 0.0 2.1 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFX97527.1 - 0.0042 16.4 0.5 0.53 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 KFX97527.1 - 0.0062 15.6 0.2 0.055 12.5 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KFX97527.1 - 0.0092 15.6 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFX97527.1 - 0.015 15.7 0.0 2.3 8.7 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFX97527.1 - 0.023 15.2 0.3 2 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFX97527.1 - 0.023 14.4 0.1 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX97527.1 - 0.038 13.5 0.1 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KFX97527.1 - 0.065 13.2 0.6 12 5.9 0.0 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX97527.1 - 0.12 12.1 0.0 4.3 7.1 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KFX97527.1 - 0.16 12.0 0.2 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFX97527.1 - 0.36 10.4 3.3 1.1 8.8 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KFX97527.1 - 0.37 10.5 1.3 12 5.5 0.1 3.1 4 0 0 4 4 2 0 AAA domain NDUFA12 PF05071.16 KFX97529.1 - 1.7e-31 108.9 3.8 2e-31 108.6 3.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 2-oxogl_dehyd_N PF16078.5 KFX97529.1 - 0.62 9.7 4.0 1.7 8.3 1.6 2.1 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus PLDc_2 PF13091.6 KFX97530.1 - 0.00088 19.2 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain DnaG_DnaB_bind PF08278.11 KFX97530.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Glyco_hydro_76 PF03663.14 KFX97545.1 - 8.9e-139 463.1 14.0 8.9e-139 463.1 14.0 1.5 2 0 0 2 2 1 1 Glycosyl hydrolase family 76 ORC4_C PF14629.6 KFX97545.1 - 1.9e-65 220.3 0.0 3.1e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KFX97545.1 - 8e-16 58.9 0.4 2e-15 57.6 0.4 1.7 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 KFX97545.1 - 6.2e-11 41.7 2.3 1.3e-10 40.7 2.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KFX97545.1 - 2.3e-10 40.2 6.8 4e-10 39.4 6.8 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 KFX97545.1 - 2e-09 37.9 0.0 5.6e-09 36.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 KFX97545.1 - 2.7e-07 30.7 0.1 9e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KFX97545.1 - 3.3e-07 30.8 0.0 8.3e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFX97545.1 - 9.9e-05 22.4 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFX97545.1 - 0.00012 21.3 0.1 0.0002 20.6 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KFX97545.1 - 0.00047 19.5 0.0 0.00074 18.8 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.6 KFX97545.1 - 0.00055 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFX97545.1 - 0.00066 19.7 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX97545.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 KFX97545.1 - 0.001 18.5 0.0 0.054 12.9 0.0 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 KFX97545.1 - 0.0039 16.9 0.1 0.0072 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KFX97545.1 - 0.0043 16.9 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 KFX97545.1 - 0.0082 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain C1_1 PF00130.22 KFX97545.1 - 0.011 15.6 3.5 0.022 14.6 3.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_33 PF13671.6 KFX97545.1 - 0.011 15.9 0.2 0.061 13.5 0.2 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 KFX97545.1 - 0.042 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 KFX97545.1 - 0.045 13.1 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KFX97545.1 - 0.059 13.3 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 NTPase PIF1 PF05970.14 KFX97545.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase T2SSE PF00437.20 KFX97545.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KFX97545.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFX97545.1 - 0.086 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FYVE_2 PF02318.16 KFX97545.1 - 0.09 13.0 1.6 0.21 11.8 1.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger RuBisCO_large_N PF02788.16 KFX97545.1 - 0.11 12.7 0.2 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain AAA_5 PF07728.14 KFX97545.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Prok-RING_1 PF14446.6 KFX97545.1 - 0.13 12.2 3.1 0.26 11.2 3.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 cobW PF02492.19 KFX97545.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KFX97545.1 - 0.15 12.6 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DLIC PF05783.11 KFX97545.1 - 0.15 10.9 0.8 1.2 7.9 0.1 2.3 1 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) C1_2 PF03107.16 KFX97545.1 - 0.18 12.1 1.7 0.41 11.0 1.7 1.6 1 0 0 1 1 1 0 C1 domain SRP54 PF00448.22 KFX97545.1 - 0.19 11.3 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zf_RING PF16744.5 KFX97545.1 - 1.3 9.2 4.8 2.8 8.1 4.8 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-piccolo PF05715.13 KFX97545.1 - 2.8 8.1 6.5 7.4 6.8 6.5 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger CUE PF02845.16 KFX97547.1 - 6e-12 45.0 0.0 8.9e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KFX97547.1 - 0.14 11.8 7.9 0.27 10.9 7.9 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 KFX97547.1 - 0.23 11.5 2.0 0.4 10.7 2.0 1.3 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Kinesin PF00225.23 KFX97550.1 - 7.5e-93 311.1 0.0 1.2e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX97550.1 - 8e-20 71.3 0.0 3.1e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KFX97550.1 - 0.0082 16.0 3.6 0.53 10.2 0.6 2.8 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase FlxA PF14282.6 KFX97550.1 - 0.042 13.8 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 FlxA-like protein NARP1 PF12569.8 KFX97551.1 - 0.065 12.1 2.4 0.085 11.8 2.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4175 PF13779.6 KFX97551.1 - 2.4 6.0 14.0 2.2 6.1 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sod_Cu PF00080.20 KFX97552.1 - 5.5e-15 55.8 1.6 8.1e-15 55.2 1.6 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) LSM PF01423.22 KFX97553.1 - 1.3e-21 76.1 0.0 1.4e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KFX97553.1 - 0.003 17.6 0.1 0.0035 17.4 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KFX97553.1 - 0.064 13.4 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain NHL PF01436.21 KFX97554.1 - 0.00019 21.3 0.0 0.066 13.3 0.0 3.7 4 0 0 4 4 4 1 NHL repeat DUF5074 PF16819.5 KFX97554.1 - 0.051 13.6 0.0 0.33 11.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5074) DUF5050 PF16472.5 KFX97554.1 - 0.052 12.8 0.0 0.85 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5050) SGL PF08450.12 KFX97554.1 - 0.07 12.7 0.1 5 6.6 0.0 2.3 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region RhoGAP PF00620.27 KFX97555.1 - 7.5e-35 120.0 0.0 1.4e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KFX97555.1 - 1.5e-32 111.6 39.0 1.3e-11 44.5 6.6 5.0 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 KFX97555.1 - 8 6.2 6.5 0.44 10.2 0.1 2.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain UQ_con PF00179.26 KFX97556.1 - 1.7e-40 137.9 0.0 2.3e-29 101.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 KFX97556.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 UEV domain Pox_Ag35 PF03286.14 KFX97557.1 - 0.54 10.0 10.1 0.75 9.6 10.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Red1 PF07964.11 KFX97557.1 - 0.9 7.7 7.3 1.1 7.5 7.3 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Menin PF05053.13 KFX97557.1 - 0.98 7.7 5.1 0.97 7.7 5.1 1.1 1 0 0 1 1 1 0 Menin BTAD PF03704.17 KFX97577.1 - 0.016 15.6 0.1 0.02 15.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial transcriptional activator domain ABC2_membrane PF01061.24 KFX97587.1 - 1e-28 100.2 32.2 1.6e-28 99.6 32.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFX97587.1 - 2.7e-25 89.5 0.0 2.7e-25 89.5 0.0 2.1 3 0 0 3 3 1 1 ABC transporter RsgA_GTPase PF03193.16 KFX97587.1 - 3.2e-05 23.9 1.3 0.00016 21.6 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 KFX97587.1 - 0.00013 21.6 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFX97587.1 - 0.00019 21.9 0.0 0.00073 20.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX97587.1 - 0.00036 21.0 0.1 0.00087 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFX97587.1 - 0.002 18.0 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFX97587.1 - 0.0028 17.6 0.0 0.008 16.1 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFX97587.1 - 0.0033 17.7 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFX97587.1 - 0.0083 15.6 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KFX97587.1 - 0.023 14.9 0.5 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFX97587.1 - 0.032 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase RE_AspBHI_N PF18062.1 KFX97587.1 - 0.056 13.0 0.5 0.13 11.8 0.5 1.6 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal IstB_IS21 PF01695.17 KFX97587.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFX97587.1 - 0.069 13.7 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX97587.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KFX97587.1 - 0.12 12.5 3.1 0.99 9.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KFX97587.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KFX97587.1 - 0.28 10.3 22.6 0.6 9.2 22.6 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein Mucin-like PF16058.5 KFX97602.1 - 4.2 7.5 10.1 1.2 9.3 6.3 2.0 1 1 0 1 1 1 0 Mucin-like 2OG-FeII_Oxy PF03171.20 KFX97609.1 - 4.7e-15 55.9 0.0 1.1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFX97609.1 - 1.9e-06 28.6 0.0 3.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans_2 PF11951.8 KFX97610.1 - 1.2e-08 34.2 0.2 1.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 KFX97611.1 - 7.9e-12 46.4 0.0 1.5e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX97611.1 - 1.3e-11 44.6 0.0 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX97611.1 - 0.00043 20.1 1.6 0.025 14.4 1.2 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.20 KFX97612.1 - 9.8e-26 90.9 0.0 1.3e-24 87.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX97612.1 - 1.1e-14 55.5 0.0 2.7e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF3632 PF12311.8 KFX97612.1 - 2.4e-10 41.1 0.0 4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Hydrolase_4 PF12146.8 KFX97612.1 - 0.00018 20.8 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFX97612.1 - 0.0014 17.7 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Cation_ATPase_C PF00689.21 KFX97613.1 - 2.9e-43 147.7 5.1 2.9e-43 147.7 5.1 3.5 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX97613.1 - 2.3e-36 125.0 6.9 3.2e-36 124.6 3.3 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFX97613.1 - 5.3e-20 72.6 0.0 8.6e-09 36.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX97613.1 - 4.1e-18 65.2 0.0 8.4e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX97613.1 - 3.7e-09 36.2 0.0 9.2e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX97613.1 - 0.00072 19.4 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KFX97613.1 - 7.5 5.2 5.6 1.8 7.2 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 KFX97614.1 - 1.8e-53 177.3 18.8 6.5e-06 26.8 0.1 11.4 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KFX97614.1 - 1e-52 177.8 0.2 1.7e-52 177.1 0.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFX97614.1 - 6.9e-16 58.3 3.8 0.0029 17.9 0.1 8.0 6 2 2 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX97614.1 - 5.5e-06 25.3 13.3 0.18 10.4 0.6 6.6 4 4 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFX97614.1 - 0.0002 20.3 3.7 15 4.2 0.0 5.9 5 2 1 6 6 6 3 Nup133 N terminal like WD40_like PF17005.5 KFX97614.1 - 0.0038 16.6 0.0 0.25 10.6 0.0 3.4 3 1 1 4 4 4 1 WD40-like domain Glyco_hydro_125 PF06824.11 KFX97616.1 - 1.2e-186 620.6 0.0 1.5e-186 620.3 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MFS_1 PF07690.16 KFX97616.1 - 9.5e-29 100.4 48.9 2.7e-26 92.3 30.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX97616.1 - 0.003 16.5 7.5 0.003 16.5 7.5 2.1 1 1 1 2 2 2 1 MFS_1 like family Glyco_hydro_47 PF01532.20 KFX97617.1 - 3.6e-142 474.5 0.0 4.2e-142 474.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMO-like PF00743.19 KFX97618.1 - 8.6e-42 143.2 0.0 4.3e-27 94.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX97618.1 - 2.5e-14 53.2 0.0 4.7e-14 52.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97618.1 - 6.3e-12 45.4 3.2 4.9e-08 32.6 0.6 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX97618.1 - 5.6e-11 42.7 0.4 2.4e-08 34.1 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX97618.1 - 2e-10 40.3 1.4 8.7e-08 31.7 0.1 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFX97618.1 - 2.5e-10 40.5 0.2 0.00028 20.6 0.0 3.7 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX97618.1 - 8.4e-09 35.5 0.2 6.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX97618.1 - 1.1e-08 34.6 0.2 1.4e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KFX97618.1 - 5.2e-06 26.9 0.1 0.05 14.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX97618.1 - 0.0012 17.6 3.4 0.0053 15.5 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KFX97618.1 - 0.0012 18.2 0.0 0.041 13.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KFX97618.1 - 0.0028 16.7 0.7 0.29 10.1 0.1 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KFX97618.1 - 0.0029 16.9 1.1 0.23 10.8 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFX97618.1 - 0.0035 17.4 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KFX97618.1 - 0.016 14.6 0.1 0.055 12.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX97618.1 - 0.017 14.4 0.3 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 KFX97618.1 - 0.033 13.0 0.2 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 MCRA family 2-Hacid_dh_C PF02826.19 KFX97618.1 - 0.048 13.0 0.4 3.5 6.9 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pribosyltran PF00156.27 KFX97618.1 - 0.063 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase domain FAD_binding_2 PF00890.24 KFX97618.1 - 0.1 11.7 1.6 0.5 9.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KFX97618.1 - 0.12 11.4 1.5 2.6 7.0 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyridox_ox_2 PF12900.7 KFX97619.1 - 2e-36 125.1 0.0 2.6e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.29 KFX97621.1 - 4.7e-25 88.6 0.0 7e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFX97621.1 - 2.1e-11 44.0 0.3 3.8e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFX97621.1 - 0.0026 17.4 0.0 0.016 14.8 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KFX97622.1 - 3.8e-26 90.8 3.1 3.9e-07 30.7 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97622.1 - 0.00022 21.4 0.0 0.49 10.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFX97622.1 - 0.075 12.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Proteasome PF00227.26 KFX97623.1 - 2.9e-30 105.2 0.0 3.3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Viral_DNA_bp PF00747.17 KFX97623.1 - 0.19 8.8 0.0 0.24 8.5 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein Glyco_hydro_3_C PF01915.22 KFX97625.1 - 5.5e-53 180.0 0.0 8.2e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX97625.1 - 7e-38 130.8 0.0 1.2e-37 130.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX97625.1 - 2.7e-21 75.4 0.0 5.7e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_2 PF08276.11 KFX97626.1 - 0.00015 21.8 0.0 0.00044 20.3 0.0 1.8 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.26 KFX97626.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 PAN domain Inv-AAD PF18785.1 KFX97626.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase ThiF PF00899.21 KFX97627.1 - 4.3e-44 150.7 0.0 6.6e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KFX97627.1 - 5.2e-06 26.7 0.9 4.4e-05 23.8 0.9 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFX97627.1 - 9.1e-05 22.9 0.1 0.0002 21.8 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFX97627.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFX97627.1 - 0.0068 16.7 0.2 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 KFX97627.1 - 0.031 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KFX97627.1 - 0.032 13.5 0.1 0.051 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX97627.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFX97627.1 - 0.044 13.4 0.3 0.088 12.4 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX97627.1 - 0.14 12.7 0.9 0.54 10.9 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX97629.1 - 9.2e-11 41.8 0.1 1.8e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFX97629.1 - 2.3e-08 33.9 0.7 4.6e-08 32.8 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX97629.1 - 1.6e-07 30.8 1.6 2.9e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX97629.1 - 1.3e-06 28.3 1.2 2.5e-06 27.3 1.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX97629.1 - 2e-06 27.2 0.2 1.1e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX97629.1 - 4.4e-06 27.2 0.2 9e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX97629.1 - 1.6e-05 23.8 0.5 2.9e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KFX97629.1 - 1.6e-05 24.4 0.0 0.00013 21.4 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFX97629.1 - 0.00017 20.9 0.6 0.0003 20.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX97629.1 - 0.00041 19.7 0.1 0.00069 19.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX97629.1 - 0.0011 18.2 0.4 0.86 8.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KFX97629.1 - 0.0038 16.4 0.1 0.0056 15.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KFX97629.1 - 0.0039 16.4 0.2 0.0068 15.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFX97629.1 - 0.071 12.4 0.3 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KFX97629.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MCRA PF06100.11 KFX97629.1 - 0.099 11.4 0.0 0.21 10.3 0.0 1.5 2 0 0 2 2 2 0 MCRA family Phage_lambda_P PF06992.11 KFX97629.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Replication protein P ApbA PF02558.16 KFX97629.1 - 1.7 8.3 3.7 2.7 7.6 0.7 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AAA_12 PF13087.6 KFX97630.1 - 2.3e-35 122.0 0.0 6.4e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFX97630.1 - 5.9e-26 91.8 0.1 3e-24 86.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX97630.1 - 1.2e-10 41.5 0.0 5e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFX97630.1 - 2.3e-09 37.7 0.0 4.6e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFX97630.1 - 1.3e-06 28.3 0.0 0.016 15.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFX97630.1 - 0.00065 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFX97630.1 - 0.012 14.9 0.5 0.57 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFX97630.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 KFX97630.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.32 KFX97631.1 - 8.1e-12 45.5 1.1 1.3 10.0 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.12 KFX97631.1 - 0.032 14.2 0.1 4.9 7.2 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KFX97631.1 - 0.048 14.0 0.0 26 5.2 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SelR PF01641.18 KFX97635.1 - 1e-48 164.4 0.1 1.7e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 KFX97635.1 - 0.01 15.9 0.6 0.61 10.2 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFX97635.1 - 0.015 15.0 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Tnp_zf-ribbon_2 PF13842.6 KFX97635.1 - 0.037 14.8 0.2 12 6.8 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Yippee-Mis18 PF03226.14 KFX97635.1 - 0.081 13.1 0.4 0.25 11.6 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 KFX97635.1 - 0.13 11.8 1.1 4.9 6.8 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Fungal_trans_2 PF11951.8 KFX97636.1 - 3.5e-28 98.5 0.8 4.3e-28 98.2 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KFX97637.1 - 1.6e-32 113.5 0.0 1.9e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX97637.1 - 6.6e-06 26.3 0.1 2.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX97637.1 - 5.9e-05 22.5 0.0 0.05 12.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX97637.1 - 0.0026 17.1 0.1 0.1 11.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KFX97637.1 - 0.0041 17.6 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX97637.1 - 0.014 14.5 0.2 0.022 13.8 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KFX97637.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX97637.1 - 0.02 14.9 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 KFX97637.1 - 0.038 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 KFX97637.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KFX97637.1 - 0.053 12.9 0.1 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 KFX97637.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFX97637.1 - 0.097 11.4 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 KFX97637.1 - 0.21 10.6 0.5 5.8 5.9 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein Abhydrolase_1 PF00561.20 KFX97638.1 - 1.5e-27 96.8 0.0 2.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX97638.1 - 4.1e-14 52.4 0.0 2.4e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX97638.1 - 6.9e-10 39.9 0.1 9.5e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFX97638.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein HSP70 PF00012.20 KFX97639.1 - 1.4e-261 869.0 13.1 1.6e-261 868.8 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFX97639.1 - 2e-16 59.7 1.8 4.8e-15 55.2 0.1 2.1 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFX97639.1 - 0.0061 17.0 5.2 4.5 7.7 0.4 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 KFX97639.1 - 0.11 11.7 5.0 0.021 14.1 1.3 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 HEPPP_synt_1 PF07307.11 KFX97639.1 - 0.22 11.1 1.4 0.45 10.1 1.4 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydantoinase_A PF01968.18 KFX97639.1 - 0.26 10.5 0.1 0.26 10.5 0.1 2.3 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase GTP_EFTU PF00009.27 KFX97640.1 - 3.7e-49 166.9 0.0 5.6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KFX97640.1 - 1.4e-25 89.4 0.7 3e-25 88.3 0.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KFX97640.1 - 1.7e-09 37.9 0.1 6.1e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFX97640.1 - 1.4e-08 34.8 0.0 0.00012 22.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KFX97640.1 - 1.2e-07 32.0 0.0 3.3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KFX97640.1 - 0.0035 17.6 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX97640.1 - 0.036 13.5 0.0 2.4 7.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFX97640.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin Arrestin_C PF02752.22 KFX97641.1 - 8.1e-18 65.2 0.0 2.2e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFX97641.1 - 2.1e-09 37.6 0.0 3.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KFX97641.1 - 0.0032 17.2 0.0 0.062 13.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin_N terminal like WD40 PF00400.32 KFX97642.1 - 7.2e-14 52.0 7.3 0.00013 22.7 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97642.1 - 1.6e-09 37.9 0.0 0.0025 18.1 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KFX97642.1 - 9.8e-05 20.6 0.0 0.0013 16.8 0.0 1.9 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 KFX97642.1 - 0.0004 20.3 0.0 0.0039 17.1 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KFX97642.1 - 0.015 13.8 0.0 0.065 11.8 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.12 KFX97642.1 - 0.019 14.9 0.0 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EF_assoc_2 PF08356.12 KFX97643.1 - 2.2e-35 120.5 0.0 4.3e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFX97643.1 - 8.5e-31 105.4 0.3 1.6e-30 104.5 0.3 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KFX97643.1 - 7.9e-26 90.6 0.0 1e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFX97643.1 - 1.3e-13 51.2 0.0 1.3e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFX97643.1 - 1.3e-09 38.1 0.0 3.7e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFX97643.1 - 9e-09 34.3 1.5 0.0034 16.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFX97643.1 - 7e-07 28.7 1.7 0.022 14.6 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFX97643.1 - 9e-07 29.3 0.5 0.00061 20.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 KFX97643.1 - 9e-06 25.8 1.5 0.18 11.9 0.0 3.6 3 1 1 4 4 3 2 Dynamin family AAA_16 PF13191.6 KFX97643.1 - 4.8e-05 23.8 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFX97643.1 - 0.00016 21.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_5 PF13202.6 KFX97643.1 - 0.00026 20.3 3.3 0.07 12.7 1.7 2.7 2 0 0 2 2 2 1 EF hand AAA_28 PF13521.6 KFX97643.1 - 0.00066 20.0 0.0 0.63 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.6 KFX97643.1 - 0.0011 18.8 2.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.6 KFX97643.1 - 0.0023 18.2 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX97643.1 - 0.0045 17.4 0.0 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFX97643.1 - 0.014 15.1 0.1 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KFX97643.1 - 0.02 14.8 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 GTP_EFTU PF00009.27 KFX97643.1 - 0.021 14.4 0.0 13 5.3 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.6 KFX97643.1 - 0.021 14.7 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 EF hand RsgA_GTPase PF03193.16 KFX97643.1 - 0.025 14.5 0.1 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 KFX97643.1 - 0.041 14.4 0.1 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFX97643.1 - 0.1 12.1 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFX97643.1 - 0.12 12.6 0.0 21 5.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX97643.1 - 0.12 12.8 0.0 7 7.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PriCT_1 PF08708.11 KFX97643.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) FtsK_SpoIIIE PF01580.18 KFX97643.1 - 0.14 11.5 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 KFX97643.1 - 0.14 11.3 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2433 PF10360.9 KFX97644.1 - 1.2e-49 167.5 0.0 2e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KFX97644.1 - 0.00064 19.9 0.0 0.0035 17.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFX97644.1 - 0.0024 18.4 0.0 0.0055 17.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.13 KFX97644.1 - 0.76 9.7 10.0 1.2 9.1 10.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ubie_methyltran PF01209.18 KFX97645.1 - 2.2e-83 279.2 0.0 2.9e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KFX97645.1 - 7.1e-19 68.3 0.0 1.5e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97645.1 - 1e-17 64.5 0.0 3.5e-17 62.8 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97645.1 - 1.8e-14 53.8 0.0 2.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97645.1 - 1.7e-11 44.8 0.0 3.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97645.1 - 5.4e-09 36.1 0.0 8.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFX97645.1 - 0.00093 19.1 0.0 0.0021 17.9 0.0 1.6 2 0 0 2 2 2 1 Hypothetical methyltransferase Glyco_transf_90 PF05686.12 KFX97645.1 - 0.054 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Sororin PF09666.10 KFX97645.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Sororin protein E1_dh PF00676.20 KFX97646.1 - 4.4e-84 282.0 0.0 5.4e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFX97646.1 - 0.00017 21.4 0.1 0.0013 18.5 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 KFX97646.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DUF1771 PF08590.10 KFX97647.1 - 3.9e-07 30.3 5.5 3.9e-07 30.3 5.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFX97647.1 - 8.7e-05 22.8 0.7 0.00022 21.5 0.7 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 KFX97647.1 - 0.00022 20.8 0.0 0.00052 19.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 KFX97647.1 - 0.00037 20.0 0.0 0.00087 18.8 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif HECT PF00632.25 KFX97648.1 - 1e-75 255.1 0.0 1.9e-75 254.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KFX97648.1 - 0.27 11.3 6.9 38 4.5 0.2 5.9 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat Ribophorin_I PF04597.14 KFX97654.1 - 1.2e-151 505.8 3.4 1.4e-151 505.6 3.4 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 KFX97655.1 - 4.2e-82 275.2 0.0 5.4e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFX97655.1 - 2.2e-71 239.9 0.0 1.5e-70 237.2 0.0 1.9 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 KFX97655.1 - 0.035 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ank_2 PF12796.7 KFX97656.1 - 0.012 16.2 0.0 0.11 13.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) p25-alpha PF05517.12 KFX97659.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 p25-alpha Rhodanese PF00581.20 KFX97660.1 - 7.4e-14 52.2 0.1 2e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Grg1 PF11034.8 KFX97661.1 - 3e-31 107.4 8.5 3.3e-31 107.3 8.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 N-SET PF11764.8 KFX97681.1 - 9.6e-51 172.3 0.7 9.6e-51 172.3 0.7 2.4 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KFX97681.1 - 5.4e-22 77.2 0.1 1.4e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KFX97681.1 - 1.3e-18 68.0 11.4 4e-18 66.4 0.1 4.5 2 2 0 4 4 4 2 SET domain INSIG PF07281.12 KFX97682.1 - 1.9e-76 256.5 2.5 2.3e-76 256.1 2.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) HNF-1_N PF04814.13 KFX97693.1 - 0.99 10.0 9.9 0.68 10.5 7.8 1.7 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus GST_C_2 PF13410.6 KFX97694.1 - 8.3e-09 35.4 0.2 1.5e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX97694.1 - 0.00097 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MazE_antitoxin PF04014.18 KFX97694.1 - 0.23 11.5 1.3 0.73 9.8 0.0 2.4 3 0 0 3 3 3 0 Antidote-toxin recognition MazE, bacterial antitoxin Ribosomal_L9_N PF01281.19 KFX97695.1 - 2.5e-13 49.4 0.0 5.9e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 KFX97695.1 - 9.9e-05 22.7 1.5 0.00034 21.0 0.2 2.5 3 1 0 3 3 3 1 Ribosomal protein L9, C-terminal domain F_bP_aldolase PF01116.20 KFX97696.1 - 1.7e-89 300.0 0.0 1.9e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 KFX97697.1 - 1.5e-64 218.2 0.3 3.7e-56 190.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein zf-C2H2 PF00096.26 KFX97709.1 - 2.3e-05 24.6 7.2 0.0041 17.5 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX97709.1 - 0.017 15.9 6.4 0.62 11.0 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX97709.1 - 0.61 10.6 7.2 1.1 9.8 2.4 3.0 2 0 0 2 2 2 0 Zinc-finger double domain DUF5549 PF17703.1 KFX97716.1 - 0.025 14.2 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) AMP-binding PF00501.28 KFX97717.1 - 1.4e-89 300.6 0.4 1.8e-89 300.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX97717.1 - 1.7e-26 93.0 0.1 2.9e-25 89.0 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFX97717.1 - 1.6e-18 66.4 1.5 4.5e-18 64.9 1.5 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus NMDAR2_C PF10565.9 KFX97717.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus p450 PF00067.22 KFX97731.1 - 2e-66 224.7 0.0 2.3e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 KFX97732.1 - 5.4e-10 39.8 0.0 8.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97732.1 - 8.7e-09 35.4 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFX97732.1 - 3.2e-08 33.2 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFX97732.1 - 3.8e-06 27.4 0.0 5.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX97732.1 - 7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFX97732.1 - 7.6e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97732.1 - 0.00017 22.3 0.0 0.00027 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX97732.1 - 0.0031 17.0 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KFX97732.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFX97732.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFX97732.1 - 0.045 13.1 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 KFX97732.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DOT1 PF08123.13 KFX97732.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 KFX97732.1 - 0.19 11.0 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain GMC_oxred_N PF00732.19 KFX97735.1 - 4.7e-50 170.6 0.1 6e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX97735.1 - 1.1e-36 126.6 0.1 1.8e-36 125.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KFX97735.1 - 5.7e-06 26.1 0.9 0.0002 21.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFX97735.1 - 9.6e-06 25.1 0.0 0.062 12.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX97735.1 - 2.1e-05 23.8 0.1 0.0007 18.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFX97735.1 - 0.00021 21.3 0.2 0.18 11.8 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX97735.1 - 0.0013 18.9 0.2 0.0033 17.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX97735.1 - 0.0014 18.0 0.2 0.046 13.0 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX97735.1 - 0.0054 15.9 0.3 0.72 8.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX97735.1 - 0.016 14.3 0.1 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFX97735.1 - 0.018 14.3 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KFX97735.1 - 0.057 12.3 0.1 0.086 11.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KFX97735.1 - 0.19 10.4 0.3 0.38 9.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Amidohydro_2 PF04909.14 KFX97737.1 - 3.7e-45 155.0 0.3 4.6e-45 154.6 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase Retrotran_gag_2 PF14223.6 KFX97737.1 - 0.17 11.6 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type COesterase PF00135.28 KFX97738.1 - 3.1e-74 250.7 0.0 4.6e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX97738.1 - 0.016 15.1 0.0 0.064 13.1 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold TPR_12 PF13424.6 KFX97739.1 - 7.1e-133 433.2 45.8 1.2e-19 70.3 0.6 6.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFX97739.1 - 1.4e-97 317.3 19.8 8e-11 41.5 0.0 11.0 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 KFX97739.1 - 7e-40 132.1 14.7 0.0001 22.1 0.0 10.3 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 KFX97739.1 - 1.3e-33 113.4 26.7 9.2e-05 22.1 0.5 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KFX97739.1 - 1.9e-23 80.7 13.5 0.018 15.2 0.1 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFX97739.1 - 4.4e-23 79.5 26.2 0.0091 16.0 0.6 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97739.1 - 1.8e-20 71.9 14.6 0.097 13.5 0.0 10.4 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFX97739.1 - 9.4e-18 64.6 13.3 5.2e-05 23.8 0.3 8.0 6 4 0 6 6 6 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX97739.1 - 2.4e-14 53.5 14.5 9.5e-06 25.2 0.9 4.2 1 1 2 4 4 4 4 MalT-like TPR region TPR_4 PF07721.14 KFX97739.1 - 7.2e-13 47.8 0.0 4 8.3 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX97739.1 - 1.6e-10 41.4 15.1 0.046 14.2 0.0 7.2 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFX97739.1 - 3.7e-10 39.5 2.5 21 5.8 0.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX97739.1 - 9.3e-10 38.6 1.6 2.8 8.2 0.0 7.2 2 1 5 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 KFX97739.1 - 3.9e-07 29.5 0.0 0.0039 16.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Atu4866 PF11512.8 KFX97739.1 - 1.5e-06 28.5 5.6 5.4 7.5 0.1 7.0 7 1 1 8 8 6 1 Agrobacterium tumefaciens protein Atu4866 DUF1925 PF09094.11 KFX97739.1 - 2.4e-05 24.6 2.6 38 4.7 0.1 6.2 6 0 0 6 6 6 0 Domain of unknown function (DUF1925) MIT PF04212.18 KFX97739.1 - 0.0014 18.7 9.3 6.9 6.8 0.0 7.0 5 1 2 7 7 7 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 KFX97739.1 - 0.0045 16.7 11.3 27 4.4 0.0 6.6 3 1 4 7 7 7 0 Tetratricopeptide repeat-like domain Ribosomal_L19 PF01245.20 KFX97739.1 - 0.036 14.0 0.5 12 5.8 0.0 2.9 2 1 1 3 3 3 0 Ribosomal protein L19 TniB PF05621.11 KFX97739.1 - 0.047 13.1 0.0 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein SgrR_N PF12793.7 KFX97739.1 - 0.05 13.8 1.0 7.8 6.7 0.1 3.0 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term AAA_22 PF13401.6 KFX97739.1 - 0.061 13.6 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NRBF2_MIT PF17169.4 KFX97739.1 - 0.31 11.3 7.2 51 4.2 0.3 5.4 5 2 1 6 6 5 0 MIT domain of nuclear receptor-binding factor 2 Mad3_BUB1_I PF08311.12 KFX97739.1 - 8.2 6.4 10.3 78 3.3 0.0 6.3 8 0 0 8 8 8 0 Mad3/BUB1 homology region 1 Sugar_tr PF00083.24 KFX97740.1 - 1.9e-86 290.7 16.7 2.2e-86 290.5 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97740.1 - 1e-14 54.2 27.6 2.6e-10 39.8 6.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 KFX97741.1 - 3.4e-112 375.4 2.0 4.6e-112 374.9 2.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX97741.1 - 4.2e-06 26.8 0.0 9.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 KFX97741.1 - 0.0046 17.2 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 KFX97741.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Amidase PF01425.21 KFX97742.1 - 1.7e-85 287.7 0.0 7e-85 285.7 0.0 1.9 2 1 0 2 2 2 1 Amidase MFS_1 PF07690.16 KFX97742.1 - 9.1e-28 97.2 47.4 1.5e-27 96.5 47.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX97742.1 - 0.0014 17.3 17.6 0.0014 17.3 17.6 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 KFX97743.1 - 2.3e-15 56.4 29.0 7.1e-09 35.0 12.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KFX97744.1 - 4.2e-06 25.8 0.4 4.1e-05 22.6 0.4 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 KFX97745.1 - 3.8e-21 76.0 0.4 1e-19 71.3 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF5119 PF17145.4 KFX97746.1 - 0.00043 20.3 0.1 16 5.3 0.1 5.0 1 1 4 5 5 5 2 Domain of unknown function (DUF5119) PC_rep PF01851.22 KFX97746.1 - 0.012 16.0 0.1 31 5.3 0.1 4.8 6 0 0 6 6 6 0 Proteasome/cyclosome repeat Bac_luciferase PF00296.20 KFX97747.1 - 1.5e-54 185.6 0.5 2.3e-54 185.0 0.5 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Methyltrn_RNA_3 PF02598.17 KFX97747.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase UNC-93 PF05978.16 KFX97748.1 - 7.5e-08 32.2 2.8 7.5e-08 32.2 2.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFX97748.1 - 2.6e-06 26.6 32.6 4.3e-06 25.9 32.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 KFX97749.1 - 3.6e-16 58.7 0.0 4.2e-15 55.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX97749.1 - 1.4e-13 50.7 0.0 4.7e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97749.1 - 5.3e-13 48.9 0.0 4.3e-12 45.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX97749.1 - 2.2e-09 37.4 0.0 1.4e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX97749.1 - 4.7e-08 32.6 0.7 2.1e-07 30.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFX97749.1 - 7.3e-06 25.8 2.8 0.1 12.2 0.1 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase Thi4 PF01946.17 KFX97749.1 - 1.2e-05 24.7 0.1 4.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFX97749.1 - 0.021 14.8 0.5 1.3 9.0 0.1 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFX97749.1 - 0.16 11.2 1.1 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KFX97749.1 - 0.26 10.5 0.5 0.46 9.7 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain F-box PF00646.33 KFX97750.1 - 0.00052 19.8 0.6 0.0013 18.6 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX97750.1 - 0.098 12.6 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like VID27 PF08553.10 KFX97751.1 - 7.5e-196 650.2 0.1 9.9e-196 649.8 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KFX97751.1 - 2.6e-74 248.8 0.5 2.6e-74 248.8 0.5 2.6 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KFX97751.1 - 1.1e-47 160.9 1.9 3.4e-47 159.2 1.1 2.1 2 0 0 2 2 2 1 VID27 PH-like domain Glyco_transf_20 PF00982.21 KFX97752.1 - 2.3e-196 653.1 0.0 2.7e-196 652.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KFX97752.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Drc1-Sld2 PF11719.8 KFX97753.1 - 1.2e-45 156.9 5.5 1.5e-45 156.6 5.5 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein GOLGA2L5 PF15070.6 KFX97759.1 - 0.061 12.0 2.3 0.1 11.2 2.3 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KFX97759.1 - 0.17 11.7 1.5 0.33 10.7 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator zf-CHY PF05495.12 KFX97761.1 - 8.9e-12 45.3 10.4 8.9e-12 45.3 10.4 3.6 3 0 0 3 3 3 1 CHY zinc finger zinc_ribbon_15 PF17032.5 KFX97761.1 - 8.3 7.2 21.3 8.9 7.1 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon family Cpn60_TCP1 PF00118.24 KFX97762.1 - 1.1e-159 532.2 4.5 1.3e-159 532.0 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Torus PF16131.5 KFX97763.1 - 0.0017 19.0 34.4 0.36 11.5 0.7 7.2 4 1 3 7 7 7 4 Torus domain RepB PF07506.11 KFX97763.1 - 0.22 11.6 1.6 1.4 9.0 0.2 2.4 1 1 1 2 2 2 0 RepB plasmid partitioning protein adh_short_C2 PF13561.6 KFX97769.1 - 9.5e-35 120.2 0.0 1.2e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX97769.1 - 8.4e-22 77.6 0.0 1.6e-21 76.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFX97769.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Methyltransf_25 PF13649.6 KFX97770.1 - 3.1e-16 59.8 0.0 4.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97770.1 - 4.5e-14 52.9 0.0 7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97770.1 - 1.7e-08 34.5 0.0 4.8e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97770.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97770.1 - 3.9e-06 27.5 0.0 7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFX97770.1 - 3.3e-05 23.3 0.0 4.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFX97770.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Albumin_I_a PF16720.5 KFX97770.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Albumin I chain a adh_short PF00106.25 KFX97771.1 - 4.6e-27 94.8 1.3 8e-27 94.0 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97771.1 - 1e-16 61.2 1.0 1.5e-16 60.7 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_10 PF13673.7 KFX97771.1 - 6.3e-10 39.1 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX97771.1 - 1.7e-09 38.0 0.1 4.9e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97771.1 - 1.3e-08 35.0 0.1 3.9e-08 33.6 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family KR PF08659.10 KFX97771.1 - 6.4e-08 32.7 0.1 3.5e-07 30.3 0.0 2.2 3 0 0 3 3 3 1 KR domain FR47 PF08445.10 KFX97771.1 - 8.1e-06 25.7 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein NAD_binding_10 PF13460.6 KFX97771.1 - 0.00095 19.1 0.2 0.0024 17.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Acetyltransf_9 PF13527.7 KFX97771.1 - 0.0017 18.5 0.1 0.04 14.0 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX97771.1 - 0.032 14.4 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyoxalase PF00903.25 KFX97772.1 - 7.6e-06 26.1 0.0 1.7e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Herpes_LMP1 PF05297.11 KFX97773.1 - 0.58 9.3 2.2 1.1 8.3 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ank PF00023.30 KFX97774.1 - 2.7e-11 43.4 0.0 7.5e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 KFX97774.1 - 1.8e-09 37.5 0.4 5.9e-09 35.9 0.4 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 KFX97774.1 - 4.9e-09 36.7 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX97774.1 - 2.4e-08 34.4 0.0 6.8e-07 29.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX97774.1 - 4.6e-08 32.7 0.1 0.0006 20.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFX97774.1 - 7.7e-08 32.5 0.1 0.00041 20.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Cauli_VI PF01693.16 KFX97775.1 - 5.3e-38 129.1 6.3 3.2e-20 72.2 0.6 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KFX97775.1 - 5.2e-36 124.0 0.0 8.9e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFX97775.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like dCMP_cyt_deam_1 PF00383.23 KFX97776.1 - 6.3e-08 32.4 0.2 2.1e-07 30.8 0.2 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFX97776.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFX97776.1 - 0.13 12.4 0.0 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 APOBEC3 Arm PF00514.23 KFX97777.1 - 2.7e-13 49.4 15.2 3.1e-05 23.9 0.1 9.1 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFX97777.1 - 4.7e-07 29.5 10.9 3.1 8.3 0.1 7.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KFX97777.1 - 5.9e-07 29.9 5.2 0.11 13.1 0.1 6.2 6 0 0 6 6 6 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KFX97777.1 - 0.046 13.8 0.6 2 8.6 0.2 3.2 2 1 1 3 3 3 0 V-ATPase subunit H DUF3361 PF11841.8 KFX97777.1 - 0.075 13.0 0.3 0.4 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) DUF4148 PF13663.6 KFX97777.1 - 0.53 10.5 6.1 5.2 7.3 0.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4148) 6PF2K PF01591.18 KFX97778.1 - 8.6e-63 211.6 0.0 1.1e-43 149.1 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFX97778.1 - 1.8e-26 93.1 0.0 7e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFX97778.1 - 0.0037 17.4 0.2 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KFX97778.1 - 0.022 14.2 0.0 0.063 12.7 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CARD PF00619.21 KFX97778.1 - 0.15 12.1 0.2 0.48 10.5 0.2 1.8 1 1 0 1 1 1 0 Caspase recruitment domain CHZ PF09649.10 KFX97779.1 - 3.8e-19 67.8 2.9 3.8e-19 67.8 2.9 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.14 KFX97779.1 - 0.0036 17.7 1.6 0.0085 16.5 1.6 1.7 1 1 0 1 1 1 1 RNA polymerase III RPC4 BUD22 PF09073.10 KFX97779.1 - 0.0069 15.8 9.4 0.007 15.8 9.4 1.0 1 0 0 1 1 1 1 BUD22 PPP4R2 PF09184.11 KFX97779.1 - 0.8 9.2 10.1 1 8.9 10.1 1.3 1 0 0 1 1 1 0 PPP4R2 Use1 PF09753.9 KFX97780.1 - 0.00042 20.1 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sipho_Gp157 PF05565.11 KFX97780.1 - 0.033 14.2 0.1 0.039 13.9 0.1 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Apc15p PF05841.11 KFX97781.1 - 7.5e-18 65.5 0.8 3.3e-17 63.5 0.8 1.9 1 1 0 1 1 1 1 Apc15p protein GATase_2 PF00310.21 KFX97782.1 - 3.2e-181 602.6 0.0 4.9e-181 602.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFX97782.1 - 1e-156 521.8 0.0 1.8e-156 520.9 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KFX97782.1 - 2.9e-111 371.5 0.0 1.4e-109 366.0 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KFX97782.1 - 1.2e-85 285.9 5.1 2e-85 285.2 5.1 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KFX97782.1 - 1.1e-21 76.7 0.1 2.4e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KFX97782.1 - 2.2e-21 76.4 0.0 9.2e-21 74.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX97782.1 - 3.2e-08 33.7 0.0 1.1e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX97782.1 - 8.3e-08 32.2 0.2 0.00044 19.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX97782.1 - 5.4e-07 30.1 0.0 0.0014 19.1 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX97782.1 - 1.9e-05 23.6 0.0 5.9e-05 21.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KFX97782.1 - 3.7e-05 23.2 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX97782.1 - 0.00019 20.8 0.5 0.033 13.5 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX97782.1 - 0.0013 17.9 0.1 0.0047 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFX97782.1 - 0.003 16.8 0.1 0.015 14.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KFX97782.1 - 0.0049 17.3 1.7 3.7 8.1 0.1 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KFX97782.1 - 0.0077 16.3 0.4 5.8 7.0 0.0 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 KFX97782.1 - 0.0079 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX97782.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFX97782.1 - 0.019 13.4 0.1 6 5.2 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 KFX97782.1 - 0.03 13.4 0.6 0.12 11.4 0.6 2.0 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 KFX97782.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 KFX97782.1 - 0.07 12.4 0.1 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFX97782.1 - 0.076 12.0 0.1 0.74 8.8 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein VTC PF09359.10 KFX97783.1 - 5.8e-95 317.8 0.6 9.8e-95 317.1 0.6 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KFX97783.1 - 1.1e-13 51.4 3.3 2.5e-13 50.2 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KFX97783.1 - 5e-09 36.6 10.7 0.00056 20.0 1.4 3.5 1 1 2 3 3 3 3 SPX domain Seryl_tRNA_N PF02403.22 KFX97783.1 - 0.43 10.8 5.0 0.36 11.1 1.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nic96 PF04097.14 KFX97785.1 - 1.2e-201 671.5 0.0 1.6e-201 671.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 UPF0029 PF01205.19 KFX97785.1 - 4.5e-29 100.9 0.0 1.2e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Seipin PF06775.14 KFX97786.1 - 1.8e-62 210.9 0.0 2.3e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.9 KFX97786.1 - 0.047 13.7 0.3 0.047 13.7 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CorA PF01544.18 KFX97787.1 - 2.4e-08 33.7 0.3 4e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spermine_synth PF01564.17 KFX97789.1 - 2.6e-09 36.7 0.0 4.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KFX97789.1 - 0.0034 18.1 0.0 0.0083 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97789.1 - 0.0072 17.0 0.0 0.02 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97789.1 - 0.009 16.6 0.0 0.037 14.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97789.1 - 0.021 14.6 0.0 0.05 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFX97789.1 - 0.058 13.3 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase AlaDh_PNT_C PF01262.21 KFX97789.1 - 0.079 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.6 KFX97789.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KFX97790.1 - 5.6e-22 78.0 0.8 1.2e-21 77.0 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain LSM PF01423.22 KFX97806.1 - 9.8e-15 54.0 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain Chorismate_bind PF00425.18 KFX97807.1 - 3.1e-91 305.5 0.0 4.9e-89 298.3 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 KFX97807.1 - 9.2e-28 97.2 0.1 4.4e-23 82.1 0.0 4.0 3 1 1 4 4 4 2 Anthranilate synthase component I, N terminal region NAPRTase_C PF17956.1 KFX97807.1 - 0.024 15.1 0.1 0.072 13.5 0.0 1.9 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain SKG6 PF08693.10 KFX97808.1 - 0.22 11.0 4.9 0.58 9.6 4.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sugar_tr PF00083.24 KFX97816.1 - 2.8e-85 286.9 21.0 3.2e-85 286.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97816.1 - 1.7e-30 106.1 24.8 3e-27 95.5 17.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX97816.1 - 4.6e-06 25.4 1.5 4.6e-06 25.4 1.5 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_4 PF06779.14 KFX97816.1 - 4.6e-05 22.9 0.1 4.6e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFX97816.1 - 0.00046 18.7 4.1 0.0015 17.0 1.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 KFX97816.1 - 0.075 12.9 0.3 0.075 12.9 0.3 2.9 3 0 0 3 3 3 0 YrhK-like protein Fungal_trans_2 PF11951.8 KFX97817.1 - 9.9e-22 77.3 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KFX97817.1 - 1.2e-19 70.5 0.3 2.2e-19 69.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX97817.1 - 3.2e-06 27.1 1.4 7.1e-06 26.0 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.11 KFX97818.1 - 4.7e-10 39.0 0.0 9.3e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX97818.1 - 1.9e-06 27.6 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 KFX97818.1 - 6.4e-06 25.9 0.0 7.5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 KFX97818.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_4 PF08007.12 KFX97818.1 - 0.0077 15.7 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.14 KFX97818.1 - 0.0085 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_7 PF12973.7 KFX97818.1 - 0.047 13.6 0.0 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 ChrR Cupin-like domain Cupin_6 PF12852.7 KFX97818.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Cupin AA_permease PF00324.21 KFX97819.1 - 4.8e-142 473.9 35.4 5.8e-142 473.6 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX97819.1 - 3.6e-38 131.5 38.1 4.4e-38 131.2 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease Internalin_N PF12354.8 KFX97819.1 - 3.6 7.7 5.6 2.4 8.3 0.0 3.5 3 1 1 4 4 4 0 Bacterial adhesion/invasion protein N terminal MFS_1 PF07690.16 KFX97820.1 - 2.2e-38 132.1 24.1 2.2e-38 132.1 24.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97820.1 - 3.4e-12 46.0 16.4 3.4e-12 46.0 16.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 KFX97821.1 - 5.5e-25 87.9 0.1 1e-24 87.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX97821.1 - 4.6e-08 33.1 11.9 9.1e-08 32.1 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex24p PF06398.11 KFX97825.1 - 1.2e-33 116.6 14.1 1.4e-33 116.4 14.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ge1_WD40 PF16529.5 KFX97826.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PARP PF00644.20 KFX97827.1 - 2.1e-12 47.1 0.0 2.4e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain cobW PF02492.19 KFX97829.1 - 4.5e-41 140.4 0.0 6.5e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KFX97829.1 - 0.00022 21.1 0.0 0.00054 19.9 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF463 PF04317.12 KFX97829.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 BESS PF02944.20 KFX97829.1 - 0.023 14.5 0.5 0.038 13.8 0.5 1.3 1 0 0 1 1 1 0 BESS motif AAA_22 PF13401.6 KFX97829.1 - 0.023 14.9 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFX97829.1 - 0.023 14.4 0.4 0.3 10.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KFX97829.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase YL1 PF05764.13 KFX97831.1 - 0.26 11.4 9.2 0.36 10.9 9.2 1.3 1 1 0 1 1 1 0 YL1 nuclear protein BEX PF04538.12 KFX97831.1 - 0.48 11.0 4.5 0.61 10.7 4.5 1.1 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF1752 PF08550.10 KFX97843.1 - 5.1e-10 39.0 4.1 9.7e-10 38.1 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SPATA24 PF15175.6 KFX97856.1 - 0.065 13.1 2.0 0.11 12.3 2.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 FMN_dh PF01070.18 KFX97870.1 - 8.6e-107 357.2 0.0 1e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFX97870.1 - 3.6e-20 71.9 0.0 8.5e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFX97870.1 - 2.1e-07 30.4 0.2 3.7e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFX97870.1 - 1.6e-05 24.1 0.3 0.0001 21.4 0.1 2.1 2 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFX97870.1 - 0.013 14.9 0.2 0.021 14.3 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase BPL_C PF02237.17 KFX97870.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain ThiG PF05690.14 KFX97870.1 - 0.017 14.5 0.0 5.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFX97870.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFX97870.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 KFX97870.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase adh_short_C2 PF13561.6 KFX97871.1 - 1.1e-35 123.4 3.4 1.6e-35 122.8 3.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX97871.1 - 5.1e-30 104.4 2.7 7.2e-30 103.9 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX97871.1 - 2e-07 31.1 3.6 2.5e-06 27.5 3.6 2.0 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KFX97871.1 - 0.16 12.0 0.4 0.36 10.9 0.4 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1772 PF08592.11 KFX97872.1 - 1e-08 35.6 0.1 1.7e-08 34.9 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) YusW PF14039.6 KFX97872.1 - 0.22 12.0 0.0 0.32 11.5 0.0 1.2 1 0 0 1 1 1 0 YusW-like protein DUF1932 PF09130.11 KFX97873.1 - 1e-21 76.7 0.1 2.8e-21 75.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KFX97873.1 - 5.9e-06 26.8 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFX97873.1 - 6.2e-06 26.5 0.0 9.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFX97873.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KFX97873.1 - 0.03 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 KFX97873.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KFX97873.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase zf-RanBP PF00641.18 KFX97874.1 - 0.28 10.5 3.2 0.6 9.5 3.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others ASFV_J13L PF05568.11 KFX97874.1 - 3 7.6 4.8 0.89 9.3 0.2 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein RRM_1 PF00076.22 KFX97875.1 - 7e-17 61.0 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFX97875.1 - 6.1e-08 33.1 13.2 6.1e-08 33.1 13.2 2.9 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 p450 PF00067.22 KFX97877.1 - 2.9e-73 247.2 0.0 1.2e-72 245.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 SBF PF01758.16 KFX97882.1 - 2.8e-50 170.7 14.3 2.8e-50 170.7 14.3 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family LMWPc PF01451.21 KFX97883.1 - 8.6e-20 71.6 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase ABATE PF07336.11 KFX97883.1 - 0.0049 17.5 0.3 0.0094 16.6 0.3 1.4 1 0 0 1 1 1 1 Putative stress-induced transcription regulator DUF1488 PF07369.11 KFX97883.1 - 0.025 14.6 0.2 0.051 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Pyr_redox_2 PF07992.14 KFX97884.1 - 3.9e-46 157.6 0.7 4.6e-46 157.4 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX97884.1 - 6.9e-18 65.0 1.8 1.2e-15 57.8 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97884.1 - 2.4e-16 59.8 0.3 1.2e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFX97884.1 - 6.6e-06 26.5 0.1 0.0017 18.8 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFX97884.1 - 2.3e-05 24.6 0.5 0.019 15.2 0.1 3.1 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX97884.1 - 0.0001 21.6 0.1 0.00042 19.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KFX97884.1 - 0.013 14.6 5.1 0.17 10.9 0.3 3.0 2 1 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 KFX97884.1 - 0.02 14.1 0.4 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KFX97884.1 - 0.026 13.6 4.9 1.7 7.6 0.3 3.4 3 1 1 4 4 4 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KFX97884.1 - 0.027 13.6 0.0 0.2 10.7 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KFX97884.1 - 0.029 13.2 0.1 0.29 9.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 KFX97884.1 - 0.039 13.5 1.2 2.5 7.6 0.2 2.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX97884.1 - 0.1 11.3 0.4 1.2 7.8 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 KFX97884.1 - 0.1 11.9 1.6 0.27 10.5 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Bul1_C PF04426.12 KFX97885.1 - 0.2 11.0 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Arrestin_N PF00339.29 KFX97886.1 - 5.1e-07 29.9 0.0 3.1e-06 27.3 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain HLH PF00010.26 KFX97886.1 - 3.5e-06 26.9 1.0 8.2e-06 25.7 1.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_72 PF03198.14 KFX97887.1 - 2.3e-129 431.2 0.1 2.9e-129 430.8 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFX97887.1 - 3.5e-05 23.4 0.1 0.00027 20.5 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_17 PF00332.18 KFX97887.1 - 0.052 13.1 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TAP42 PF04177.12 KFX97887.1 - 0.27 10.3 0.0 0.41 9.7 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family SPX PF03105.19 KFX97888.1 - 4.8 7.0 7.0 5.9 6.7 7.0 1.2 1 0 0 1 1 1 0 SPX domain Chromate_transp PF02417.15 KFX97889.1 - 2.9e-58 196.5 35.4 4.5e-34 117.9 12.9 2.5 3 0 0 3 3 3 2 Chromate transporter TPALS PF18178.1 KFX97889.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family CcmH PF03918.14 KFX97889.1 - 0.22 10.8 0.0 0.22 10.8 0.0 2.4 4 0 0 4 4 4 0 Cytochrome C biogenesis protein Meth_synt_2 PF01717.18 KFX97892.1 - 7.4e-153 508.5 0.0 1.2e-147 491.4 0.0 2.9 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFX97892.1 - 1e-119 399.8 0.8 5.3e-113 377.7 0.0 3.3 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFX97892.1 - 0.00033 19.9 0.1 0.086 12.0 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 KFX97892.1 - 0.037 13.9 0.2 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Antitoxin VbhA SHOCT PF09851.9 KFX97892.1 - 0.96 9.3 8.4 0.15 11.8 0.3 3.0 3 0 0 3 3 3 0 Short C-terminal domain Sugar_tr PF00083.24 KFX97895.1 - 1.8e-92 310.6 24.4 2.1e-92 310.3 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97895.1 - 4.8e-25 88.2 65.2 3.2e-21 75.6 40.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX97895.1 - 0.00024 19.6 2.9 0.00024 19.6 2.9 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KFX97895.1 - 0.0006 18.4 3.9 0.0006 18.4 3.9 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PalH PF08733.10 KFX97895.1 - 1.2 8.1 5.7 2.9 6.8 5.7 1.6 1 0 0 1 1 1 0 PalH/RIM21 DUF1774 PF08611.10 KFX97895.1 - 7.1 7.0 7.6 0.66 10.3 0.1 3.0 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) Amidohydro_1 PF01979.20 KFX97896.1 - 1.3e-58 199.0 0.0 1.9e-58 198.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX97896.1 - 3.8e-05 23.4 0.4 0.0046 16.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_61 PF03443.14 KFX97897.1 - 1.4e-66 224.4 0.1 2.8e-66 223.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Dyp_perox PF04261.12 KFX97898.1 - 2.1e-86 289.9 0.0 2.4e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family cobW PF02492.19 KFX97900.1 - 3.2e-34 118.0 0.0 4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFX97900.1 - 7.4e-06 25.1 0.1 0.004 16.2 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KFX97900.1 - 0.0026 18.3 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFX97900.1 - 0.0028 17.7 0.0 0.011 15.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 KFX97900.1 - 0.061 13.3 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KFX97900.1 - 0.092 13.1 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFX97900.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hyd_65N_2 PF14498.6 KFX97906.1 - 8e-52 176.4 0.0 1.2e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HET PF06985.11 KFX97907.1 - 2.1e-21 76.8 0.0 4.3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_transf_34 PF05637.12 KFX97908.1 - 2.4e-72 243.5 0.0 3.9e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pyridoxal_deC PF00282.19 KFX97908.1 - 1.1e-13 50.6 0.0 1.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFX97908.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V PMI_typeI PF01238.21 KFX97909.1 - 3.1e-65 220.8 0.0 2.4e-64 217.9 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KFX97909.1 - 0.0015 18.2 0.2 1.2 8.9 0.2 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KFX97909.1 - 0.1 12.5 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain AMP-binding PF00501.28 KFX97912.1 - 6.3e-88 295.2 0.0 7.8e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX97912.1 - 2.2e-17 63.8 0.0 5.8e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KFX97912.1 - 0.00025 20.1 0.0 0.00091 18.2 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KFX97912.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain Glyco_hydro_61 PF03443.14 KFX97913.1 - 2.6e-58 197.3 0.0 3.7e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_M60_C PF18630.1 KFX97913.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase M60 C-terminal domain NAD_binding_2 PF03446.15 KFX97914.1 - 1e-25 90.8 0.0 1.9e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFX97914.1 - 4.8e-10 39.7 0.1 8.8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFX97914.1 - 2.7e-07 31.1 0.0 7.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFX97914.1 - 1e-06 28.8 0.0 3.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX97914.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sugar_tr PF00083.24 KFX97915.1 - 1.7e-72 244.7 12.1 3.6e-71 240.4 6.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX97915.1 - 2.9e-18 65.9 19.7 3.7e-18 65.6 19.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX97915.1 - 0.0094 14.4 0.8 0.014 13.8 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM40 PF15817.5 KFX97915.1 - 0.095 12.5 0.4 0.22 11.3 0.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 40 family TrmO_C PF18389.1 KFX97915.1 - 0.19 11.8 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain Zn_clus PF00172.18 KFX97916.1 - 9e-09 35.3 8.4 1.6e-08 34.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX97916.1 - 0.067 12.2 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KFX97917.1 - 9.4e-65 218.4 0.0 2.3e-64 217.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX97917.1 - 1.7e-49 169.0 0.0 2.8e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX97917.1 - 2.7e-21 75.5 1.2 5.8e-21 74.4 0.8 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KFX97917.1 - 2.1e-15 56.8 0.1 4e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KFX97917.1 - 0.018 15.3 0.4 0.45 10.8 0.1 2.4 2 0 0 2 2 2 0 CARDB Acetyltransf_9 PF13527.7 KFX97926.1 - 1.7e-05 24.9 0.1 3.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX97926.1 - 0.0077 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97926.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_2 PF12796.7 KFX97927.1 - 7.3e-33 113.0 1.5 4.1e-11 43.3 0.1 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX97927.1 - 2.5e-32 110.8 0.4 1.2e-08 35.4 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX97927.1 - 2.2e-27 94.8 1.9 2.6e-07 30.8 0.0 6.2 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX97927.1 - 2.4e-20 72.0 0.1 0.018 15.5 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 KFX97927.1 - 8.7e-20 68.7 0.1 0.00075 19.8 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat DBD_Tnp_Hermes PF10683.9 KFX97927.1 - 0.037 13.7 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF2387 PF09526.10 KFX97927.1 - 0.13 12.4 0.6 0.29 11.3 0.6 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 KFX97927.1 - 0.21 11.6 2.1 2.6 8.1 0.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon FAD_binding_3 PF01494.19 KFX97928.1 - 4.7e-17 62.3 0.1 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KFX97928.1 - 0.029 13.2 0.1 0.079 11.8 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase CFEM PF05730.11 KFX97931.1 - 1.3e-10 41.2 10.6 1.9e-10 40.7 10.6 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_61 PF03443.14 KFX97932.1 - 5.9e-67 225.6 0.0 7.4e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KFX97932.1 - 0.014 15.6 0.1 0.072 13.4 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase WD40 PF00400.32 KFX97945.1 - 5.3e-17 61.9 11.6 0.0047 17.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat DEAD PF00270.29 KFX97946.1 - 8.7e-44 149.4 0.0 1.5e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_pol_Rpb5_C PF01191.19 KFX97946.1 - 2e-31 107.7 0.1 5.8e-31 106.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFX97946.1 - 8.5e-27 93.6 0.0 1.7e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Helicase_C PF00271.31 KFX97946.1 - 3e-21 75.8 0.0 5.7e-20 71.7 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97946.1 - 4.3e-05 23.6 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mrr_cat PF04471.12 KFX97946.1 - 0.045 13.8 0.1 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease SecA_DEAD PF07517.14 KFX97946.1 - 0.13 11.6 0.1 1.7 7.9 0.0 2.3 3 0 0 3 3 3 0 SecA DEAD-like domain CENP-F_leu_zip PF10473.9 KFX97947.1 - 0.00043 20.3 12.4 0.00043 20.3 12.4 4.2 2 2 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KFX97947.1 - 0.047 13.9 0.3 0.047 13.9 0.3 5.5 4 1 1 5 5 5 0 ABC transporter C-terminal domain Propeptide_C1 PF08127.13 KFX97947.1 - 0.11 12.4 0.1 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C1 propeptide FlaC_arch PF05377.11 KFX97947.1 - 6.4 7.2 11.8 33 5.0 0.1 5.0 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF4239 PF14023.6 KFX97947.1 - 9.4 5.9 6.5 2.9 7.6 0.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) GTP1_OBG PF01018.22 KFX97949.1 - 8.4e-39 132.6 5.3 3.3e-29 101.5 5.2 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KFX97949.1 - 5.1e-23 81.3 0.0 9.4e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX97949.1 - 1.9e-07 30.7 0.1 4.6e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KFX97949.1 - 0.18 12.3 1.1 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Zn_clus PF00172.18 KFX97951.1 - 5.8e-09 35.9 10.3 1e-08 35.1 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX97951.1 - 1.3e-07 31.0 0.0 3.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KFX97952.1 - 7.7e-88 295.6 3.8 9.9e-88 295.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFX97952.1 - 4.9e-08 33.2 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Sugar_tr PF00083.24 KFX97953.1 - 5.3e-85 286.0 23.9 6e-85 285.8 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97953.1 - 2.8e-15 56.1 29.2 2.8e-15 56.1 29.2 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX97953.1 - 9.3e-07 27.7 21.7 0.00085 18.0 4.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Romo1 PF10247.9 KFX97953.1 - 0.02 15.3 1.6 0.084 13.2 1.6 2.1 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 MFS_1_like PF12832.7 KFX97953.1 - 0.043 12.7 11.7 0.086 11.7 5.6 2.4 2 0 0 2 2 2 0 MFS_1 like family NmrA PF05368.13 KFX97954.1 - 8.9e-37 126.9 0.0 1.2e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX97954.1 - 1.1e-19 71.0 0.0 1.3e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX97954.1 - 0.00048 19.7 0.0 0.0018 17.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX97954.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KFX97954.1 - 0.015 14.5 0.0 0.031 13.4 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 KFX97954.1 - 0.02 13.9 0.0 0.041 12.9 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX97954.1 - 0.097 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KFX97954.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CDH PF02611.15 KFX97955.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Meth_synt_2 PF01717.18 KFX97955.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Cobalamin-independent synthase, Catalytic domain NACHT PF05729.12 KFX97956.1 - 3.1e-09 37.0 0.0 6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KFX97956.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFX97956.1 - 0.00052 20.7 0.2 0.0015 19.2 0.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KFX97956.1 - 0.0013 18.5 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 KFX97956.1 - 0.0015 18.9 0.1 0.0076 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX97956.1 - 0.034 14.4 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cutinase PF01083.22 KFX97956.1 - 0.038 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase Epimerase PF01370.21 KFX97957.1 - 6.9e-17 61.7 0.0 1.5e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX97957.1 - 2.2e-05 24.0 0.2 4.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX97957.1 - 0.0004 19.6 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KFX97957.1 - 0.0053 16.7 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX97957.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-oxoacid_dh PF00198.23 KFX97957.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) RmlD_sub_bind PF04321.17 KFX97957.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KFX97957.1 - 0.16 11.5 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Ank_2 PF12796.7 KFX97958.1 - 6.6e-34 116.3 16.9 1.1e-12 48.4 0.7 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX97958.1 - 2.7e-24 85.2 4.7 1.9e-06 28.3 0.0 5.7 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX97958.1 - 1.9e-21 73.8 6.6 0.0077 16.7 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KFX97958.1 - 3.3e-19 68.4 17.5 0.0087 16.5 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KFX97958.1 - 1.1e-17 63.8 11.1 3e-05 24.2 0.2 6.0 1 1 6 7 7 7 6 Ankyrin repeats (many copies) FLgD_tudor PF13861.6 KFX97958.1 - 0.036 14.3 0.0 0.5 10.6 0.0 2.9 2 1 0 2 2 2 0 FlgD Tudor-like domain CholecysA-Rec_N PF09193.10 KFX97958.1 - 0.059 13.4 3.0 16 5.6 0.0 4.0 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal VWA_3_C PF18571.1 KFX97958.1 - 0.53 10.2 2.8 9.7 6.1 0.2 2.9 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Nif11 PF07862.11 KFX97958.1 - 0.87 9.9 4.5 98 3.4 0.0 4.2 4 1 0 5 5 5 0 Nif11 domain p450 PF00067.22 KFX97960.1 - 9.9e-52 176.2 0.0 1.3e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asparaginase_II PF06089.12 KFX97960.1 - 0.052 12.6 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 L-asparaginase II Peptidase_C48 PF02902.19 KFX97961.1 - 0.00036 20.4 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.29 KFX97961.1 - 0.018 14.9 8.3 0.036 14.0 8.3 1.5 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.19 KFX97961.1 - 0.057 13.3 3.9 0.33 11.0 3.9 2.4 1 0 0 1 1 1 0 AT hook motif HrpB7 PF09486.10 KFX97961.1 - 0.073 13.4 1.2 0.14 12.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CENP-Q PF13094.6 KFX97961.1 - 0.42 10.8 5.1 0.45 10.7 1.3 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.9 KFX97961.1 - 2.2 7.3 7.8 5.1 6.1 2.8 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KFX97961.1 - 3.7 7.6 7.0 12 5.9 0.2 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KFX97961.1 - 4 7.5 7.6 17 5.4 1.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 KFX97961.1 - 5.1 7.2 7.0 1.2 9.2 1.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Serinc PF03348.15 KFX97964.1 - 2.2e-165 550.7 6.2 2.5e-165 550.6 6.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adipogenin PF15202.6 KFX97964.1 - 0.74 9.9 4.4 22 5.2 0.3 2.9 2 0 0 2 2 2 0 Adipogenin adh_short PF00106.25 KFX97965.1 - 2.9e-37 128.0 0.0 5.2e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97965.1 - 2.5e-24 86.2 0.0 4.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 KFX97965.1 - 6.8e-18 64.7 25.5 6.8e-18 64.7 25.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KFX97965.1 - 4e-10 39.6 3.5 9.4e-10 38.4 3.5 1.6 1 0 0 1 1 1 1 Nodulin-like KR PF08659.10 KFX97965.1 - 4.1e-07 30.1 4.3 0.00033 20.6 0.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KFX97965.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX97965.1 - 0.0065 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FeS PF04060.13 KFX97965.1 - 1.4 8.6 4.0 7 6.4 0.4 2.7 2 0 0 2 2 2 0 Putative Fe-S cluster PGAP1 PF07819.13 KFX97966.1 - 4.9e-92 307.8 0.0 6.5e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX97966.1 - 4.2e-05 24.3 1.7 4.3e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX97966.1 - 0.0045 16.3 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX97966.1 - 0.008 15.9 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KFX97966.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KFX97966.1 - 0.034 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KFX97966.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase p450 PF00067.22 KFX97968.1 - 2.8e-33 115.4 0.0 3.3e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4 PF00097.25 KFX97971.1 - 0.0009 19.1 2.1 0.0018 18.1 2.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX97971.1 - 0.033 14.5 6.2 0.057 13.8 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFX97971.1 - 0.042 13.7 3.7 0.13 12.1 3.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97971.1 - 0.08 13.0 5.4 0.15 12.1 5.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KFX97971.1 - 0.1 12.6 5.8 0.17 11.9 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-dskA_traR PF01258.17 KFX97971.1 - 1.5 8.8 6.9 14 5.8 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger APH PF01636.23 KFX97972.1 - 6.4e-10 39.4 0.0 7.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX97972.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KFX97972.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 KFX97973.1 - 6.5e-74 248.8 0.0 7.3e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 KFX97974.1 - 1.7e-09 37.3 0.0 5.6e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3887 PF13026.6 KFX97974.1 - 1.6e-06 28.8 0.0 3.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3887) DLH PF01738.18 KFX97974.1 - 4.7e-05 23.1 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFX97974.1 - 6.5e-05 23.6 0.1 0.00013 22.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KFX97974.1 - 0.0003 20.8 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 KFX97974.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KFX97974.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KFX97974.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain CRISPR_Cse2 PF09485.10 KFX97974.1 - 0.13 12.8 0.0 29 5.2 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DBD_HTH PF18430.1 KFX97974.1 - 0.13 12.0 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative DNA-binding domain Abhydrolase_1 PF00561.20 KFX97974.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold FMO-like PF00743.19 KFX97975.1 - 1.4e-14 53.4 0.0 1.5e-12 46.7 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX97975.1 - 6.1e-13 48.7 0.0 2.9e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX97975.1 - 2e-11 43.7 0.0 5e-08 32.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX97975.1 - 1.1e-09 38.4 0.0 1.2e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX97975.1 - 2.7e-08 33.4 0.0 1.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFX97975.1 - 2.5e-06 27.3 1.2 0.056 13.0 0.1 4.3 3 2 1 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFX97975.1 - 2.6e-06 26.8 0.0 0.001 18.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFX97975.1 - 0.00011 22.7 0.0 0.065 13.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX97975.1 - 0.00051 20.1 0.2 4.1 7.4 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFX97975.1 - 0.0029 16.8 0.1 0.28 10.2 0.4 2.8 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KFX97975.1 - 0.0057 15.9 0.0 19 4.3 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 KFX97975.1 - 0.02 14.0 0.0 15 4.5 0.0 3.7 4 0 0 4 4 4 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KFX97975.1 - 0.024 14.7 0.0 0.36 10.9 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFX97975.1 - 0.025 13.7 1.3 2.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFX97975.1 - 0.082 12.2 0.1 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GCIP PF13324.6 KFX97976.1 - 0.06 12.9 0.5 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting adh_short PF00106.25 KFX97977.1 - 2.9e-35 121.5 0.1 3.9e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97977.1 - 4.8e-27 95.0 0.1 7.8e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97977.1 - 3.5e-05 23.8 3.2 0.00047 20.1 3.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX97977.1 - 0.00012 21.7 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KFX97977.1 - 0.0022 17.8 0.7 0.0062 16.4 0.1 1.7 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 KFX97977.1 - 0.0043 16.2 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.13 KFX97977.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) POR PF01558.18 KFX97977.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase FA_hydroxylase PF04116.13 KFX97978.1 - 9.6e-22 77.8 10.6 9.6e-22 77.8 10.6 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3712 PF12505.8 KFX97979.1 - 6.6e-35 120.1 2.1 4e-34 117.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) CRAL_TRIO PF00650.20 KFX97980.1 - 3.3e-42 143.9 0.0 6.8e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX97980.1 - 1e-08 35.2 0.4 4.5e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFX97980.1 - 5.8e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_tran_28_C PF04101.16 KFX97981.1 - 0.15 12.0 0.2 0.55 10.2 0.0 2.0 3 0 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain Pre-PUA PF17832.1 KFX97982.1 - 4 8.2 7.0 0.54 11.0 2.4 1.9 1 1 1 2 2 2 0 Pre-PUA-like domain adh_short PF00106.25 KFX97983.1 - 5.5e-16 58.6 2.0 3.7e-15 55.9 1.1 2.4 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97983.1 - 7e-11 42.1 1.1 4e-10 39.6 1.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97983.1 - 0.00013 21.9 0.7 0.00021 21.2 0.3 1.5 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KFX97983.1 - 0.00058 19.5 0.2 0.0011 18.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFX97983.1 - 0.0023 17.9 0.9 0.0046 16.9 0.9 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFX97983.1 - 0.099 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 KFX97983.1 - 0.19 12.0 1.0 4.9 7.4 0.3 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pec_lyase_C PF00544.19 KFX97984.1 - 1.9e-13 50.5 6.7 1.8e-11 44.1 6.7 2.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX97984.1 - 0.00024 21.0 12.5 0.0013 18.6 6.5 2.9 1 1 3 4 4 4 3 Right handed beta helix region COesterase PF00135.28 KFX97985.1 - 6.7e-78 262.8 0.0 1.1e-77 262.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Pectinesterase PF01095.19 KFX97985.1 - 1.7e-41 141.9 1.1 3.8e-40 137.4 1.0 2.3 2 0 0 2 2 2 1 Pectinesterase Abhydrolase_3 PF07859.13 KFX97985.1 - 1.5e-06 28.2 0.4 1.4e-05 25.0 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pox_MCEL PF03291.16 KFX97999.1 - 4.6e-38 131.2 0.0 6.2e-20 71.6 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme zf-Nse PF11789.8 KFX98000.1 - 5.7e-15 54.9 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFX98000.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 KFX98000.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger MFS_1 PF07690.16 KFX98003.1 - 8.9e-43 146.6 30.0 8.9e-43 146.6 30.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX98003.1 - 3.7e-08 32.3 3.4 5.7e-08 31.6 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFX98003.1 - 0.00034 20.0 5.0 0.00034 20.0 5.0 1.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TF_Otx PF03529.13 KFX98003.1 - 0.086 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Otx1 transcription factor MAPEG PF01124.18 KFX98004.1 - 3.9e-16 59.1 3.2 5.3e-16 58.7 3.2 1.1 1 0 0 1 1 1 1 MAPEG family DUF3433 PF11915.8 KFX98012.1 - 2.9e-23 82.1 18.7 1.3e-13 51.2 5.4 4.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) LMF1 PF06762.14 KFX98012.1 - 2.8 6.9 11.7 0.014 14.5 2.0 1.9 2 1 0 2 2 2 0 Lipase maturation factor Mo-co_dimer PF03404.16 KFX98013.1 - 1.3e-59 200.1 0.1 2.4e-59 199.3 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KFX98013.1 - 7.6e-54 181.9 0.0 1.5e-53 181.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KFX98013.1 - 2e-32 111.5 0.0 3.2e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFX98013.1 - 5.2e-29 101.1 0.0 1.3e-28 99.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KFX98013.1 - 7.3e-19 67.7 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFX98013.1 - 0.0028 17.8 0.1 0.21 11.7 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 KFX98014.1 - 1.4e-45 155.8 0.0 2.4e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KFX98014.1 - 5.3e-26 91.4 14.9 8.3e-26 90.7 14.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NIR_SIR PF01077.22 KFX98014.1 - 1e-20 73.8 0.0 2.1e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KFX98014.1 - 3.5e-16 59.5 0.9 2.6e-14 53.5 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KFX98014.1 - 4.7e-15 55.4 0.0 1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 KFX98014.1 - 7.9e-15 55.0 4.9 1.5e-11 44.4 6.1 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KFX98014.1 - 6.8e-11 42.0 0.1 2.5e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KFX98014.1 - 4.7e-09 36.0 0.0 2.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KFX98014.1 - 5.2e-05 23.1 0.2 0.098 12.6 0.0 3.4 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KFX98014.1 - 0.0079 16.2 1.1 5.6 6.9 0.1 3.2 4 0 0 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KFX98014.1 - 0.015 14.6 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pox_A14 PF05767.12 KFX98014.1 - 0.095 12.9 0.1 0.73 10.0 0.1 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 LacY_symp PF01306.19 KFX98014.1 - 0.16 10.7 2.2 0.11 11.3 0.4 1.5 2 0 0 2 2 2 0 LacY proton/sugar symporter AlaDh_PNT_C PF01262.21 KFX98014.1 - 0.25 10.6 0.7 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFX98014.1 - 0.62 9.1 3.1 35 3.3 2.1 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX98014.1 - 0.78 8.8 3.3 5.7 5.9 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain GST_N_3 PF13417.6 KFX98015.1 - 3.2e-15 56.3 0.0 6.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX98015.1 - 8.7e-12 45.2 0.0 2.5e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX98015.1 - 2.4e-11 43.8 0.0 5.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX98015.1 - 3.5e-10 39.9 0.1 5.4e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX98015.1 - 4.8e-09 36.3 0.1 7.6e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX98015.1 - 8e-06 25.8 0.1 1.7e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL_2 PF13472.6 KFX98016.1 - 2.1e-10 41.3 0.9 2.7e-10 40.9 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Hex_IIIa PF02455.16 KFX98016.1 - 0.095 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) VWA_2 PF13519.6 KFX98017.1 - 0.011 16.4 0.0 0.029 15.0 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain MFS_1 PF07690.16 KFX98018.1 - 3.9e-36 124.7 60.6 3.8e-34 118.2 60.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_7 PF13508.7 KFX98019.1 - 1e-07 32.3 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX98019.1 - 5.3e-07 29.9 0.0 9.1e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX98019.1 - 7.2e-06 26.0 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX98019.1 - 0.012 15.7 0.2 3.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FSH1 PF03959.13 KFX98021.1 - 6.1e-18 65.3 0.0 7.4e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) RPE65 PF03055.15 KFX98022.1 - 8.6e-91 305.4 0.0 1.4e-90 304.8 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PCI PF01399.27 KFX98022.1 - 2.5e-20 72.9 0.3 8.4e-20 71.2 0.1 2.0 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFX98022.1 - 5.6e-16 58.4 2.1 2e-15 56.6 1.1 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Synaptobrevin PF00957.21 KFX98022.1 - 0.64 9.9 3.3 1.6 8.5 0.9 2.5 2 0 0 2 2 2 0 Synaptobrevin CAP_N PF01213.19 KFX98034.1 - 2.8e-111 372.0 19.4 2.8e-111 372.0 19.4 2.3 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFX98034.1 - 2.5e-59 199.4 1.1 3.6e-59 198.9 1.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribonuclease_3 PF00636.26 KFX98036.1 - 1e-07 32.5 0.0 4.2e-07 30.5 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFX98036.1 - 3.4e-07 30.5 0.0 0.00071 19.7 0.1 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KFX98036.1 - 6.9e-05 23.5 0.1 0.00024 21.7 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif La PF05383.17 KFX98037.1 - 8.4e-17 61.0 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFX98037.1 - 1e-08 34.9 0.2 2.3e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KFX98039.1 - 1.2e-16 60.2 0.0 2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF4763 PF15960.5 KFX98039.1 - 0.0041 16.5 1.2 0.0064 15.8 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) S4_2 PF13275.6 KFX98039.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 S4 domain FancD2 PF14631.6 KFX98039.1 - 0.28 8.5 2.6 0.38 8.1 2.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease INCENP_ARK-bind PF03941.15 KFX98040.1 - 1.1e-17 63.7 0.6 3.7e-17 62.0 0.0 2.3 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region HC2 PF07382.11 KFX98040.1 - 0.0019 18.3 25.5 0.0019 18.3 25.5 3.2 3 0 0 3 3 3 1 Histone H1-like nucleoprotein HC2 Phosphoesterase PF04185.14 KFX98041.1 - 5e-62 210.2 2.8 8.2e-62 209.4 2.8 1.3 1 1 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.16 KFX98042.1 - 7.2e-30 104.1 57.8 2.9e-29 102.1 57.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98042.1 - 4.1e-07 29.2 16.7 4.1e-07 29.2 16.7 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFX98042.1 - 0.62 8.3 8.5 0.084 11.1 1.6 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3435 PF11917.8 KFX98048.1 - 0.0022 17.0 0.1 0.0029 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) HTH_32 PF13565.6 KFX98060.1 - 1.9e-08 34.8 5.2 0.0019 18.8 0.8 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KFX98060.1 - 0.0082 15.9 0.3 0.014 15.2 0.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KFX98060.1 - 0.06 13.1 0.9 0.29 10.9 0.9 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFX98060.1 - 0.17 11.9 0.6 0.57 10.2 0.2 2.0 1 1 1 2 2 2 0 Winged helix-turn helix DEAD PF00270.29 KFX98061.1 - 6.1e-26 91.3 0.1 1.5e-24 86.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX98061.1 - 8.1e-23 80.9 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX98061.1 - 0.00032 20.7 0.0 0.00089 19.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFX98061.1 - 0.036 12.8 0.3 0.07 11.8 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain ATP-synt_G PF04718.15 KFX98062.1 - 2.7e-32 111.5 0.6 6.9e-32 110.3 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.12 KFX98062.1 - 8.6e-28 96.4 2.6 1.6e-27 95.5 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX98062.1 - 1.2e-16 60.9 0.0 3.8e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX98062.1 - 5.6e-06 26.0 0.4 0.00011 21.8 0.4 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DAGK_prokar PF01219.19 KFX98062.1 - 5.8 6.8 5.0 1.2 9.0 0.0 2.3 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase 2-Hacid_dh_C PF02826.19 KFX98063.1 - 3.3e-47 160.2 0.0 1.7e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX98063.1 - 6.8e-07 29.0 0.0 1.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 KFX98063.1 - 0.057 13.0 0.1 0.17 11.5 0.2 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 KFX98063.1 - 0.096 12.5 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Rossmann-like domain Mannosidase_ig PF17786.1 KFX98064.1 - 1e-17 64.5 0.2 3.4e-17 62.8 0.2 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFX98064.1 - 9.5e-09 35.9 0.2 3.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFX98064.1 - 0.00014 21.5 0.0 0.00042 20.0 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KFX98064.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFX98064.1 - 0.0064 15.6 0.1 0.028 13.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cytotoxic PF09000.10 KFX98064.1 - 0.094 13.1 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 Cytotoxic DUF1481 PF07356.12 KFX98075.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) DUF3292 PF11696.8 KFX98077.1 - 3.1e-259 861.8 0.0 3.8e-259 861.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) p450 PF00067.22 KFX98077.1 - 1e-26 93.7 0.0 5.4e-26 91.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.9 KFX98078.1 - 2.3e-13 50.3 0.0 2.2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase AMP-binding PF00501.28 KFX98079.1 - 6.1e-92 308.4 0.0 9.8e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX98079.1 - 0.0015 19.5 0.1 0.0035 18.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KFX98080.1 - 1.1e-86 289.3 11.1 1.4e-45 155.2 0.9 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98080.1 - 4e-67 226.2 3.5 5.5e-36 124.3 0.5 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KFX98080.1 - 1.3e-33 115.2 0.0 2.5e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KFX98080.1 - 3.2e-27 95.6 5.9 4.6e-14 52.7 0.4 2.9 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.19 KFX98080.1 - 3e-05 23.4 0.2 0.00037 19.8 0.0 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KFX98080.1 - 9.9e-05 22.5 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase KAP_NTPase PF07693.14 KFX98082.1 - 0.0033 16.7 0.0 0.0089 15.3 0.0 1.6 1 1 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 KFX98082.1 - 0.0037 17.7 0.1 0.0068 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KFX98082.1 - 0.004 16.2 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFX98082.1 - 0.0063 17.1 0.0 0.018 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX98082.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX98082.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KFX98082.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GSCFA PF08885.11 KFX98082.1 - 0.18 11.4 0.1 0.4 10.3 0.1 1.5 1 1 0 1 1 1 0 GSCFA family Pyr_redox_2 PF07992.14 KFX98091.1 - 1.2e-18 67.4 0.0 1.2e-12 47.7 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX98091.1 - 1.2e-18 67.4 0.0 1.4e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX98091.1 - 3.2e-16 59.4 0.2 3.6e-12 46.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFX98091.1 - 1.7e-15 56.5 0.0 4.8e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.27 KFX98091.1 - 1.4e-09 38.4 0.0 0.0009 19.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX98091.1 - 1.5e-09 38.1 0.0 1.6e-05 24.9 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFX98091.1 - 7e-09 36.2 0.4 0.02 15.4 0.1 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 KFX98091.1 - 7.8e-07 28.5 0.6 0.0024 17.0 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFX98091.1 - 9.7e-07 28.9 0.1 2.4e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KFX98091.1 - 1.9e-06 27.3 0.0 0.0063 15.9 0.0 2.5 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KFX98091.1 - 8.9e-06 25.8 0.4 0.14 12.2 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFX98091.1 - 9.3e-06 25.1 0.2 2.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KFX98091.1 - 3.7e-05 24.0 0.2 0.25 11.6 0.0 2.8 3 0 0 3 3 3 2 TrkA-N domain HI0933_like PF03486.14 KFX98091.1 - 0.00027 19.8 0.5 0.0081 14.9 0.1 3.0 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.6 KFX98091.1 - 0.00063 20.2 0.0 0.28 11.7 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding ThiF PF00899.21 KFX98091.1 - 0.00074 18.9 0.3 1.1 8.5 0.0 2.7 3 0 0 3 3 3 2 ThiF family AlaDh_PNT_C PF01262.21 KFX98091.1 - 0.0017 17.7 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFX98091.1 - 0.0094 15.1 0.3 0.0094 15.1 0.3 2.9 3 1 0 4 4 4 1 FAD binding domain XdhC_C PF13478.6 KFX98091.1 - 0.011 16.3 0.1 0.27 11.7 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 KFX98091.1 - 0.013 15.1 5.1 0.044 13.4 0.0 3.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KFX98091.1 - 0.019 14.1 1.6 2.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KFX98091.1 - 0.024 14.5 0.1 7 6.5 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 KFX98091.1 - 0.047 13.3 0.0 7.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 KFX98091.1 - 0.12 11.6 1.3 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Thi4 family Zn_clus PF00172.18 KFX98092.1 - 8.8e-09 35.3 5.8 1.6e-08 34.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WXG100 PF06013.12 KFX98092.1 - 0.13 12.6 0.4 0.33 11.2 0.4 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG TPR_8 PF13181.6 KFX98098.1 - 5.4e-22 76.1 3.8 2.2e-05 24.3 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98098.1 - 3.3e-21 74.2 2.9 3.5e-05 23.4 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98098.1 - 6e-16 57.2 12.0 0.0042 17.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98098.1 - 2e-11 43.7 14.4 0.0017 19.0 0.1 5.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX98098.1 - 1.3e-10 41.4 10.2 0.022 15.0 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98098.1 - 4.8e-10 39.0 0.9 7.8e-07 28.7 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 KFX98098.1 - 1.5e-09 38.3 6.6 1.4e-06 28.8 1.5 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX98098.1 - 5.4e-09 36.1 11.5 0.0067 16.6 0.2 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98098.1 - 4.4e-08 32.6 15.0 0.0043 17.0 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX98098.1 - 2.2e-06 27.8 1.9 0.0018 18.5 0.5 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFX98098.1 - 3.5e-06 27.4 3.6 1 9.9 0.0 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.7 KFX98098.1 - 3.4e-05 23.9 5.9 0.00071 19.7 0.2 3.3 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KFX98098.1 - 8.2e-05 22.4 8.7 0.21 11.5 0.4 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX98098.1 - 0.0092 15.2 6.9 0.021 14.0 2.6 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX98098.1 - 0.014 16.0 15.2 8.5 7.3 0.4 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98098.1 - 0.031 14.7 0.1 3.1 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KFX98098.1 - 0.041 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase G_glu_transpept PF01019.21 KFX98098.1 - 0.066 12.0 0.1 0.095 11.4 0.1 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Arm-DNA-bind_3 PF13356.6 KFX98098.1 - 0.099 13.0 0.5 0.37 11.2 0.5 2.1 1 1 0 1 1 1 0 Arm DNA-binding domain DUF676 PF05057.14 KFX98111.1 - 6.5e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KFX98111.1 - 0.00061 20.2 0.2 0.0032 17.9 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX98111.1 - 0.01 16.1 0.0 0.039 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.13 KFX98111.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FHA PF00498.26 KFX98113.1 - 9.9e-12 45.0 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KFX98113.1 - 0.033 14.5 0.0 1 9.7 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain MFS_1 PF07690.16 KFX98114.1 - 1.2e-27 96.8 29.7 1.2e-27 96.8 29.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 KFX98114.1 - 0.12 10.6 9.3 0.092 11.0 0.2 3.0 3 1 0 3 3 3 0 BT1 family Sugar_tr PF00083.24 KFX98114.1 - 3.3 6.5 31.2 93 1.7 31.1 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter HRM PF02793.22 KFX98115.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 Hormone receptor domain Sugar_tr PF00083.24 KFX98116.1 - 1.7e-73 248.0 25.0 2.4e-73 247.5 25.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98116.1 - 7.6e-15 54.7 27.2 7.6e-15 54.7 27.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 KFX98117.1 - 3.3e-50 171.4 0.0 7e-50 170.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFX98117.1 - 4.9e-23 81.9 0.2 7.8e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KFX98117.1 - 0.049 12.9 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 BNR repeat-like domain BNR PF02012.20 KFX98117.1 - 0.086 12.9 2.5 1 9.6 0.4 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.18 KFX98118.1 - 2.9e-06 26.5 0.5 5.7e-06 25.6 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3656 PF12392.8 KFX98118.1 - 0.018 15.7 0.0 0.041 14.5 0.0 1.5 1 0 0 1 1 1 0 Collagenase DUF2961 PF11175.8 KFX98119.1 - 7.1e-85 284.4 4.0 9.3e-85 284.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Adenylsucc_synt PF00709.21 KFX98125.1 - 1.5e-170 567.7 0.1 1.7e-170 567.5 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CENP-S PF15630.6 KFX98126.1 - 0.00018 21.8 0.4 0.0007 19.9 0.4 1.8 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFX98126.1 - 0.00024 21.2 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFX98126.1 - 0.00068 20.0 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFX98126.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.17 KFX98126.1 - 0.0071 16.5 0.1 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 KFX98126.1 - 0.031 14.4 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 KFX98126.1 - 0.079 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Svf1_C PF17187.4 KFX98127.1 - 1.3e-59 200.7 0.5 4.3e-59 199.0 0.1 2.0 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KFX98127.1 - 1.5e-55 187.7 0.1 2.1e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Ribosomal_L11 PF00298.19 KFX98128.1 - 2.2e-27 95.3 0.2 3.5e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFX98128.1 - 3.2e-26 90.9 0.1 5.7e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain GTP_EFTU PF00009.27 KFX98133.1 - 6.5e-54 182.4 0.0 1e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFX98133.1 - 2.2e-42 143.9 0.0 4.6e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFX98133.1 - 3.6e-13 49.7 2.9 3.6e-13 49.7 2.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFX98133.1 - 0.00064 19.8 0.1 0.019 15.0 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GLE1 PF07817.13 KFX98144.1 - 1.2e-58 198.3 0.0 1.7e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein CSRNP_N PF16019.5 KFX98144.1 - 0.023 14.6 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Ndc1_Nup PF09531.10 KFX98144.1 - 2.5 6.7 8.2 3.6 6.2 8.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNB PF00773.19 KFX98145.1 - 5.8e-88 295.4 0.0 9.4e-88 294.7 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFX98145.1 - 8.8e-26 89.7 0.1 2.7e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KFX98145.1 - 5.6e-25 87.5 0.0 1.6e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KFX98145.1 - 2.1e-06 27.8 0.0 0.011 15.9 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFX98145.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain Solute_trans_a PF03619.16 KFX98150.1 - 1.3e-86 290.4 27.5 1.5e-86 290.2 27.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AAA_23 PF13476.6 KFX98164.1 - 1.4e-35 123.6 3.2 1.4e-35 123.6 3.2 6.9 1 1 5 6 6 1 1 AAA domain AAA_21 PF13304.6 KFX98164.1 - 3.8e-09 36.8 5.6 0.0027 17.6 0.0 3.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX98164.1 - 2.4e-08 33.7 31.9 4.4e-07 29.6 31.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFX98164.1 - 1.6e-06 28.2 0.0 4.6e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFX98164.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.14 KFX98164.1 - 0.0011 18.7 1.2 0.0011 18.7 1.2 5.7 7 0 0 7 7 7 1 Rad50 zinc hook motif Phage_tail_T PF06223.12 KFX98164.1 - 0.015 15.8 1.5 0.29 11.7 0.1 3.2 3 0 0 3 3 3 0 Minor tail protein T AAA_16 PF13191.6 KFX98164.1 - 0.061 13.7 0.0 0.061 13.7 0.0 5.2 3 2 1 4 4 3 0 AAA ATPase domain AAA_15 PF13175.6 KFX98164.1 - 0.096 12.4 70.8 46 3.6 34.0 6.1 1 1 2 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KFX98164.1 - 0.11 13.1 0.1 0.11 13.1 0.1 7.1 2 1 2 5 5 3 0 ABC transporter AAA_13 PF13166.6 KFX98164.1 - 0.15 10.7 0.0 0.15 10.7 0.0 7.4 3 1 4 7 7 6 0 AAA domain GATA PF00320.27 KFX98165.1 - 3.3e-15 55.4 4.8 7.7e-15 54.2 4.8 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KFX98165.1 - 3.7e-15 56.0 0.0 8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KFX98165.1 - 1.2e-12 47.8 0.0 2.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFX98165.1 - 1.8e-08 34.5 0.0 4.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 KFX98165.1 - 8.3e-08 32.3 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KFX98165.1 - 2.4e-06 27.7 0.0 4.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold DUF5337 PF17272.2 KFX98166.1 - 0.0017 18.1 2.7 0.0017 18.1 2.7 2.5 3 0 0 3 3 3 1 Family of unknown function (DUF5337) PPP4R2 PF09184.11 KFX98167.1 - 4e-05 23.4 5.5 0.00015 21.5 3.7 2.4 1 1 0 1 1 1 1 PPP4R2 GET2 PF08690.10 KFX98167.1 - 0.8 9.3 4.1 0.16 11.6 0.7 1.5 2 0 0 2 2 2 0 GET complex subunit GET2 Hamartin PF04388.12 KFX98167.1 - 6.3 5.3 7.1 9.6 4.7 7.1 1.2 1 0 0 1 1 1 0 Hamartin protein tRNA-synt_2 PF00152.20 KFX98168.1 - 1.4e-67 228.0 0.0 1.8e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFX98168.1 - 2.4e-09 37.0 0.2 4.4e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFX98168.1 - 1.2e-05 24.9 0.0 0.0094 15.5 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 KFX98169.1 - 3.3e-20 71.5 0.7 3.9e-20 71.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 KFX98169.1 - 0.066 13.3 1.1 0.066 13.3 1.1 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF1287 PF06940.11 KFX98169.1 - 0.073 12.7 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) PG_binding_1 PF01471.18 KFX98170.1 - 0.00026 21.1 0.2 0.27 11.5 0.0 3.2 2 1 0 2 2 2 2 Putative peptidoglycan binding domain Spc7 PF08317.11 KFX98170.1 - 0.0094 14.9 5.8 0.015 14.2 5.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFX98170.1 - 0.042 14.1 8.9 0.22 11.9 7.1 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 KFX98170.1 - 0.042 12.7 2.1 0.061 12.2 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) XhlA PF10779.9 KFX98170.1 - 0.2 11.9 0.7 0.97 9.7 0.7 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 KFX98170.1 - 0.71 10.1 7.1 1.4 9.1 7.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CLTH PF10607.9 KFX98171.1 - 6.7e-24 84.5 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BAR_3 PF16746.5 KFX98171.1 - 0.0096 15.6 0.2 0.02 14.6 0.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Cytochrom_B562 PF07361.11 KFX98171.1 - 0.2 12.3 1.6 0.87 10.3 0.9 2.2 2 0 0 2 2 2 0 Cytochrome b562 ECH_1 PF00378.20 KFX98173.1 - 3.3e-42 144.5 0.0 4.3e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX98173.1 - 2.7e-23 83.0 0.0 3.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 KFX98174.1 - 1e-55 189.4 7.2 1.3e-55 189.1 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98174.1 - 3.7e-20 72.2 11.7 4.5e-20 71.9 11.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX98174.1 - 0.00024 19.8 5.3 0.077 11.5 2.6 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KFX98174.1 - 0.0015 17.9 6.0 0.0022 17.3 6.0 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFX98174.1 - 0.012 14.1 4.4 0.017 13.6 4.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) bPH_6 PF10756.9 KFX98174.1 - 0.092 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial PH domain OATP PF03137.20 KFX98174.1 - 0.1 10.9 3.8 0.11 10.8 0.2 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.12 KFX98175.1 - 1.5e-30 105.2 1.9 3.3e-30 104.2 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX98175.1 - 1.7e-24 86.2 0.3 2.8e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX98175.1 - 7.3e-11 41.9 0.2 1.2e-10 41.3 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFX98175.1 - 5.7e-05 24.2 0.1 0.00029 21.9 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX98175.1 - 0.0099 15.2 1.0 0.016 14.5 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KFX98175.1 - 0.011 15.0 0.3 0.03 13.5 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFX98175.1 - 0.011 15.3 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KFX98175.1 - 0.039 14.7 0.1 0.19 12.4 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KFX98175.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 KFX98175.1 - 0.059 13.5 0.7 0.97 9.5 1.7 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region FGGY_C PF02782.16 KFX98176.1 - 2.2e-48 164.6 0.2 3.1e-48 164.1 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX98176.1 - 5.3e-23 81.9 0.3 1.2e-20 74.1 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KFX98176.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Hexokinase BcrAD_BadFG PF01869.20 KFX98176.1 - 0.0055 16.2 0.1 0.037 13.5 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family TPR_12 PF13424.6 KFX98191.1 - 3.3e-69 229.2 58.5 3.9e-11 43.1 2.0 7.5 1 1 7 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 KFX98191.1 - 1.5e-68 225.0 44.7 2.1e-08 33.7 0.2 11.0 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98191.1 - 2.4e-38 127.1 2.7 0.017 15.3 0.0 10.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98191.1 - 2.3e-28 96.0 5.1 0.4 10.9 0.0 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX98191.1 - 4e-22 78.3 25.3 0.016 15.4 0.2 9.4 1 1 8 9 9 9 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFX98191.1 - 1.6e-21 76.6 29.4 0.0006 20.3 0.3 10.0 2 1 8 10 10 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98191.1 - 3.3e-21 73.7 11.9 0.44 10.7 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98191.1 - 3.2e-20 71.0 2.6 2.9 7.9 0.0 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KFX98191.1 - 2.1e-18 65.6 1.1 5 8.0 0.0 10.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFX98191.1 - 2.7e-18 66.1 46.2 0.045 14.1 0.4 11.1 3 1 9 12 12 11 8 Tetratricopeptide repeat PPR PF01535.20 KFX98191.1 - 5.1e-15 54.6 0.2 9.2 6.8 0.0 9.8 11 0 0 11 11 9 0 PPR repeat TPR_14 PF13428.6 KFX98191.1 - 1.8e-14 53.2 23.3 0.79 10.7 0.1 10.6 10 0 0 10 10 10 4 Tetratricopeptide repeat PPR_1 PF12854.7 KFX98191.1 - 6.3e-09 35.4 6.2 25 4.7 0.0 8.8 9 0 0 9 9 9 0 PPR repeat TPR_17 PF13431.6 KFX98191.1 - 1e-08 34.9 17.6 2.6 8.6 0.1 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98191.1 - 9.7e-08 31.6 9.8 9.8 6.0 0.0 8.5 9 0 0 9 9 9 0 TPR repeat NB-ARC PF00931.22 KFX98191.1 - 2e-05 23.9 0.0 3.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain LCAT PF02450.15 KFX98191.1 - 0.00025 20.3 0.0 0.00057 19.2 0.0 1.6 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase ATP13 PF12921.7 KFX98191.1 - 0.00034 20.4 5.3 52 3.7 0.0 7.9 2 1 5 10 10 10 0 Mitochondrial ATPase expression Fer2_2 PF01799.20 KFX98191.1 - 0.00084 19.3 0.1 11 6.1 0.0 5.8 3 2 3 7 7 7 0 [2Fe-2S] binding domain Abhydrolase_9 PF10081.9 KFX98191.1 - 0.00094 18.3 0.0 0.0043 16.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta-hydrolase family AAA_22 PF13401.6 KFX98191.1 - 0.0078 16.5 0.1 0.046 14.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain Abhydrolase_6 PF12697.7 KFX98191.1 - 0.0079 16.8 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_3 PF07720.12 KFX98191.1 - 0.011 15.7 6.6 3.1 7.9 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat PGAP1 PF07819.13 KFX98191.1 - 0.044 13.5 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein DUF1494 PF07379.11 KFX98191.1 - 0.052 13.4 7.6 36 4.2 0.0 5.4 2 1 4 7 7 7 0 Protein of unknown function (DUF1494) WbqC PF08889.11 KFX98191.1 - 0.058 13.3 9.4 22 4.9 0.2 4.9 2 2 2 5 5 5 0 WbqC-like protein family TPR_4 PF07721.14 KFX98191.1 - 0.089 13.5 22.9 12 6.9 0.1 8.4 8 0 0 8 8 7 0 Tetratricopeptide repeat AAA PF00004.29 KFX98191.1 - 0.13 12.6 0.0 0.76 10.2 0.0 2.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX98191.1 - 0.23 11.9 0.1 0.23 11.9 0.1 4.3 3 2 0 3 3 2 0 AAA ATPase domain TPR_16 PF13432.6 KFX98191.1 - 0.5 11.1 25.0 8 7.2 0.1 8.3 5 4 2 7 7 7 0 Tetratricopeptide repeat EF1_GNE PF00736.19 KFX98192.1 - 1.9e-32 111.2 1.2 3.3e-32 110.5 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFX98192.1 - 1.6e-14 54.1 6.6 4.5e-14 52.6 6.6 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KFX98192.1 - 0.015 15.5 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_transf_92 PF01697.27 KFX98205.1 - 2.5e-10 40.5 0.4 1.7e-09 37.7 0.4 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFX98205.1 - 3.9e-07 30.5 0.9 7.9e-07 29.5 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 KFX98205.1 - 0.1 12.4 0.0 0.95 9.2 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 EI24 PF07264.11 KFX98206.1 - 1.8e-14 54.4 2.2 3.1e-14 53.6 2.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FMN_dh PF01070.18 KFX98207.1 - 7e-112 373.9 0.0 9.7e-112 373.4 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Methyltransf_23 PF13489.6 KFX98207.1 - 3e-07 30.4 0.0 5.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98207.1 - 1.4e-06 28.9 0.0 3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX98207.1 - 2.3e-05 25.0 0.0 6.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX98207.1 - 2.7e-05 24.8 0.0 7.5e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NMO PF03060.15 KFX98207.1 - 3e-05 23.6 0.4 4.6e-05 23.0 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFX98207.1 - 0.00057 19.0 2.3 0.0014 17.7 2.2 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFX98207.1 - 0.00058 19.1 0.3 0.0011 18.3 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Methyltransf_31 PF13847.6 KFX98207.1 - 0.00076 19.3 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain ThiG PF05690.14 KFX98207.1 - 0.00076 18.9 0.1 0.2 10.9 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFX98207.1 - 0.0027 17.2 0.2 0.067 12.7 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein Ubie_methyltran PF01209.18 KFX98207.1 - 0.1 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family IGPS PF00218.21 KFX98207.1 - 0.19 10.9 0.2 1.1 8.4 0.1 2.2 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF3632 PF12311.8 KFX98208.1 - 1.8e-24 87.1 0.0 2.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MFS_1 PF07690.16 KFX98209.1 - 2.1e-48 165.0 41.1 1.7e-46 158.8 41.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX98209.1 - 2.9e-12 45.8 20.2 4e-12 45.4 20.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ASC PF00858.24 KFX98209.1 - 0.41 9.5 0.6 0.68 8.8 0.0 1.6 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel OATP PF03137.20 KFX98209.1 - 1.3 7.2 9.3 0.27 9.5 1.7 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DFP PF04127.15 KFX98210.1 - 4.8e-13 49.3 0.0 9.6e-06 25.6 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Rick_17kDa_Anti PF05433.15 KFX98212.1 - 1.3e-05 25.0 31.0 8.3e-05 22.4 17.4 2.1 1 1 2 3 3 3 3 Glycine zipper 2TM domain DUF755 PF05501.11 KFX98212.1 - 0.47 10.7 11.0 0.58 10.4 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 KFX98212.1 - 3.5 7.9 10.7 4.2 7.6 10.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 HlyIII PF03006.20 KFX98213.1 - 9.8e-59 198.8 17.6 1.3e-58 198.4 17.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related BA14K PF07886.11 KFX98213.1 - 0.053 13.4 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 BA14K-like protein MerC PF03203.14 KFX98213.1 - 0.08 13.4 12.3 1.9 9.0 1.5 3.6 2 1 0 3 3 3 0 MerC mercury resistance protein Phage_holin_2_1 PF04971.12 KFX98213.1 - 0.16 12.0 3.7 0.59 10.2 0.3 2.9 2 1 1 3 3 3 0 Bacteriophage P21 holin S zf-C2HC5 PF06221.13 KFX98214.1 - 3.7e-21 74.8 4.9 5.8e-21 74.2 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Aminotran_5 PF00266.19 KFX98215.1 - 5.2e-20 71.7 0.0 7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFX98215.1 - 0.00056 19.2 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFX98215.1 - 0.19 11.0 0.2 1.1 8.5 0.2 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SIR2 PF02146.17 KFX98216.1 - 1.9e-28 99.6 0.0 1.7e-09 37.8 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Beta-lactamase PF00144.24 KFX98218.1 - 1.4e-28 100.1 0.5 3.9e-28 98.6 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KFX98220.1 - 1.7e-53 181.8 16.6 1.7e-53 181.8 16.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98220.1 - 4.6e-08 32.4 8.7 4.6e-08 32.4 8.7 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KFX98220.1 - 0.00024 20.2 1.4 0.00024 20.2 1.4 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KFX98220.1 - 0.00046 18.7 5.1 0.00093 17.7 5.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LapA_dom PF06305.11 KFX98220.1 - 0.24 11.2 6.1 5 7.0 0.8 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain OATP PF03137.20 KFX98220.1 - 3.7 5.7 10.1 0.098 10.9 3.6 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_11 PF13414.6 KFX98221.1 - 6e-06 25.9 0.1 0.0022 17.6 0.0 3.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 KFX98221.1 - 1.6e-05 24.6 8.8 0.016 15.3 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98221.1 - 0.00031 21.3 2.4 10 7.3 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX98221.1 - 0.00067 19.9 2.5 0.0052 17.0 0.2 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98221.1 - 0.0011 18.6 0.2 3.2 7.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98221.1 - 0.023 15.3 0.4 1.8 9.3 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98221.1 - 0.028 14.6 1.6 67 4.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX98221.1 - 0.1 13.1 4.7 1.7 9.2 0.1 4.4 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98221.1 - 0.12 12.8 1.2 5.4 7.6 0.0 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KFX98223.1 - 9.7e-85 284.9 0.0 1.8e-84 284.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 KFX98223.1 - 2e-11 44.0 0.4 2.5e-10 40.4 0.0 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DprA_WH PF17782.1 KFX98223.1 - 0.015 15.4 0.0 0.057 13.5 0.0 2.0 1 0 0 1 1 1 0 DprA winged helix domain DUF1233 PF06806.12 KFX98223.1 - 0.14 11.8 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative excisionase (DUF1233) BLOC1_2 PF10046.9 KFX98223.1 - 0.73 10.2 8.7 0.4 11.0 4.4 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KFX98223.1 - 4.4 7.9 8.5 14 6.2 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 TRI12 PF06609.13 KFX98232.1 - 1.1e-98 331.2 25.5 1.4e-98 330.9 25.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX98232.1 - 2.6e-18 66.1 50.9 2.6e-18 66.1 50.9 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98232.1 - 6.7e-07 28.5 8.8 6.7e-07 28.5 8.8 3.6 2 2 1 3 3 3 2 Sugar (and other) transporter DUF3040 PF11239.8 KFX98232.1 - 0.15 12.3 0.2 0.15 12.3 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) TMEM100 PF16311.5 KFX98232.1 - 0.16 11.6 0.3 7.1 6.2 0.0 2.8 2 0 0 2 2 2 0 Transmembrane protein 100 Pyr_redox_3 PF13738.6 KFX98233.1 - 1.3e-10 41.0 0.1 1.5e-07 31.0 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX98233.1 - 4.2e-09 36.1 0.0 0.00025 20.4 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX98233.1 - 9.6e-08 30.9 0.0 4.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFX98233.1 - 1.9e-06 28.0 0.0 1.6e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX98233.1 - 2.1e-06 27.2 0.3 0.029 13.5 0.0 3.5 5 0 0 5 5 5 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KFX98233.1 - 2.1e-06 27.8 0.0 0.0022 18.1 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KFX98233.1 - 0.00023 21.2 0.1 0.14 12.2 0.1 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KFX98233.1 - 0.0015 18.2 1.9 1.7 8.2 0.3 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase ThiF PF00899.21 KFX98233.1 - 0.062 12.7 1.6 0.87 8.9 0.0 2.4 3 0 0 3 3 3 0 ThiF family FAD_binding_2 PF00890.24 KFX98233.1 - 0.095 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 KFX98233.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KFX98234.1 - 1.2e-20 73.4 4.0 2.7e-18 65.9 2.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX98234.1 - 1.8e-18 66.8 0.7 2.8e-18 66.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX98234.1 - 1.6e-11 45.4 0.1 3.9e-11 44.1 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX98234.1 - 0.0055 16.2 2.5 0.015 14.8 2.5 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 KFX98234.1 - 0.014 15.5 0.2 0.039 14.1 0.2 1.7 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFX98234.1 - 0.09 12.1 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Qn_am_d_aII PF14930.6 KFX98234.1 - 0.14 12.4 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II GST_N_4 PF17172.4 KFX98237.1 - 1.7e-23 83.2 0.0 3.9e-23 82.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFX98237.1 - 2.2e-10 40.2 0.0 8.4e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFX98237.1 - 9.2e-06 26.0 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KFX98237.1 - 0.0001 22.2 0.0 0.00036 20.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX98237.1 - 0.15 12.5 0.0 0.82 10.1 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain F-box-like PF12937.7 KFX98238.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KFX98238.1 - 0.69 9.9 4.4 40 4.2 0.1 3.6 3 0 0 3 3 3 0 F-box domain Acetyltransf_10 PF13673.7 KFX98239.1 - 7.7e-09 35.6 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX98239.1 - 2.4e-05 24.7 0.0 3.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX98239.1 - 3.2e-05 24.1 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFX98239.1 - 0.00011 22.3 0.2 0.017 15.2 0.1 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KFX98239.1 - 0.043 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 KFX98239.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFX98239.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Helo_like_N PF17111.5 KFX98240.1 - 5.3e-06 26.0 0.9 9.4e-06 25.1 0.9 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Myb_DNA-binding PF00249.31 KFX98240.1 - 9.5e-05 22.5 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFX98240.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Myb DNA-binding like TRAM_LAG1_CLN8 PF03798.16 KFX98241.1 - 1.6e-33 116.1 11.7 1.6e-33 116.1 11.7 1.4 2 0 0 2 2 2 1 TLC domain USP7_ICP0_bdg PF12436.8 KFX98242.1 - 4e-46 157.3 0.2 6.5e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 KFX98242.1 - 3.1e-36 125.2 0.0 4.8e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFX98242.1 - 1.2e-08 35.1 0.1 5.5e-08 33.0 0.1 2.2 1 0 0 1 1 1 1 MATH domain UCH_1 PF13423.6 KFX98242.1 - 5e-06 26.3 0.0 7.8e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPE65 PF03055.15 KFX98243.1 - 6e-94 315.8 0.3 7.2e-94 315.6 0.3 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans_2 PF11951.8 KFX98244.1 - 6.3e-06 25.2 0.4 9.5e-06 24.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98244.1 - 0.0069 16.5 2.2 0.0069 16.5 2.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase PF00394.22 KFX98245.1 - 1.1e-31 110.2 0.0 2.8e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX98245.1 - 2.2e-23 82.5 8.9 4.5e-23 81.5 1.1 3.1 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFX98245.1 - 3.8e-16 59.2 2.6 6.1e-16 58.5 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Acetyltransf_10 PF13673.7 KFX98246.1 - 1.4e-08 34.8 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX98246.1 - 1.1e-06 28.9 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX98246.1 - 2.2e-05 24.7 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFX98246.1 - 0.00037 20.6 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX98246.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KFX98246.1 - 0.074 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Pyr_redox_2 PF07992.14 KFX98247.1 - 1.7e-48 165.4 0.8 2.1e-48 165.1 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX98247.1 - 2.4e-17 63.2 1.6 3.6e-15 56.3 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX98247.1 - 3.5e-16 59.3 0.5 2.3e-14 53.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFX98247.1 - 2e-05 24.9 0.1 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFX98247.1 - 2.6e-05 24.4 0.2 0.045 14.0 0.0 3.2 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX98247.1 - 0.00012 21.4 0.1 0.00055 19.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KFX98247.1 - 0.0052 16.0 0.0 0.2 10.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFX98247.1 - 0.013 15.1 0.2 7.3 6.1 0.1 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KFX98247.1 - 0.013 14.6 3.4 1.4 7.9 0.2 3.3 3 1 1 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFX98247.1 - 0.041 12.6 0.4 0.73 8.5 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 KFX98247.1 - 0.043 13.0 0.8 3.1 7.0 0.1 2.4 2 1 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KFX98247.1 - 0.065 12.1 0.1 0.61 8.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.20 KFX98247.1 - 0.13 12.3 0.2 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFX98247.1 - 0.17 11.0 4.5 0.18 10.8 0.2 2.8 2 1 0 3 3 3 0 FAD binding domain KAR9 PF08580.10 KFX98248.1 - 0.2 10.1 8.7 0.22 10.0 8.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2076 PF09849.9 KFX98248.1 - 3.1 7.8 8.2 7.2 6.6 8.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SOG2 PF10428.9 KFX98248.1 - 3.6 6.7 15.2 4.6 6.3 15.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5427 PF10310.9 KFX98248.1 - 8.7 5.2 8.8 11 4.8 8.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hamartin PF04388.12 KFX98248.1 - 8.8 4.8 9.8 12 4.4 9.8 1.2 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.32 KFX98249.1 - 5.4e-07 30.2 16.6 0.04 14.8 0.4 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98249.1 - 0.0035 17.6 0.1 1.8 8.9 0.1 3.5 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PHD PF00628.29 KFX98249.1 - 5.8 6.9 10.2 7.8 6.5 0.2 2.8 2 1 0 2 2 2 0 PHD-finger Kinesin PF00225.23 KFX98251.1 - 8.2e-56 189.3 0.0 1.3e-55 188.6 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX98251.1 - 1e-08 35.3 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KFX98251.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX98251.1 - 0.064 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SAM_PNT PF02198.16 KFX98251.1 - 0.088 12.8 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain OPT PF03169.15 KFX98252.1 - 3.5e-131 438.8 48.8 4e-131 438.7 48.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein COesterase PF00135.28 KFX98253.1 - 5.3e-84 282.9 0.0 6.4e-81 272.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX98253.1 - 1.2e-09 38.3 0.0 1.8e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KFX98253.1 - 0.0053 16.3 0.2 0.013 15.0 0.2 1.7 1 0 0 1 1 1 1 Esterase PHB depolymerase Metallophos PF00149.28 KFX98254.1 - 8.9e-19 68.8 0.5 1.4e-18 68.1 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFX98254.1 - 4.1e-17 62.8 1.2 4.1e-17 62.8 1.2 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KFX98254.1 - 7.8e-16 58.4 0.6 7.8e-16 58.4 0.6 2.3 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KFX98254.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 KFX98254.1 - 0.1 13.0 0.7 0.33 11.3 0.5 1.9 2 0 0 2 2 2 0 Fibronectin type III domain Peroxidase_2 PF01328.17 KFX98255.1 - 1.7e-46 159.1 0.0 2.3e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.11 KFX98256.1 - 1.8e-27 96.5 0.1 3.2e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 KFX98257.1 - 0.00018 21.3 0.2 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFX98257.1 - 0.0093 15.8 0.4 0.0093 15.8 0.4 2.1 2 0 0 2 2 2 1 F-box-like HeLo PF14479.6 KFX98258.1 - 1.6e-10 41.2 0.2 2.9e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KFX98258.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98258.1 - 0.031 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ras PF00071.22 KFX98265.1 - 0.0045 16.6 0.0 0.0059 16.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX98265.1 - 0.019 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 KFX98275.1 - 2.6e-34 118.7 54.3 9.2e-27 93.9 38.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MASE2 PF05230.11 KFX98275.1 - 1.1 9.4 14.0 1 9.5 3.1 3.6 3 1 0 3 3 3 0 MASE2 domain GCV_T_C PF08669.11 KFX98276.1 - 1.8e-22 79.1 0.2 3e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.21 KFX98276.1 - 3.5e-18 65.9 0.2 1.2e-17 64.1 0.1 1.8 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain CybS PF05328.12 KFX98278.1 - 2.7e-49 166.3 0.0 3.5e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TPPK_C PF12555.8 KFX98278.1 - 0.0045 17.0 0.1 4.3 7.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphokinase C terminal zf-AN1 PF01428.16 KFX98282.1 - 9.9e-13 48.0 6.5 9.9e-13 48.0 6.5 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFX98282.1 - 0.87 10.0 7.0 0.38 11.2 4.9 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain CAF1A PF12253.8 KFX98293.1 - 1.3e-23 83.0 3.6 1.3e-23 83.0 3.6 3.4 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Mitofilin PF09731.9 KFX98293.1 - 0.4 9.5 31.0 0.68 8.7 31.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GAGA_bind PF06217.12 KFX98293.1 - 6.1 7.0 14.4 12 6.1 14.4 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Borrelia_P83 PF05262.11 KFX98293.1 - 7.1 5.0 38.4 11 4.3 38.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_transf_17 PF04724.13 KFX98294.1 - 0.049 12.7 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 17 SLT_2 PF13406.6 KFX98294.1 - 0.07 12.3 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Siah-Interact_N PF09032.11 KFX98297.1 - 0.015 15.6 1.0 0.036 14.4 1.0 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal FAS_I_H PF18314.1 KFX98297.1 - 0.052 13.2 0.6 0.087 12.4 0.6 1.3 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Peptidase_S8 PF00082.22 KFX98298.1 - 4.6e-35 121.3 15.2 7.8e-35 120.6 15.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFX98298.1 - 1.3e-06 29.0 2.0 1.4e-06 28.8 0.7 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Arginase PF00491.21 KFX98299.1 - 3.5e-24 85.8 0.0 4.1e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family HNH_2 PF13391.6 KFX98326.1 - 2.6e-09 37.1 0.0 5.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Dak1 PF02733.17 KFX98333.1 - 4e-103 344.6 4.3 7.7e-103 343.6 4.3 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KFX98333.1 - 1.3e-44 152.2 3.8 2.2e-44 151.4 3.8 1.4 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KFX98334.1 - 1.7e-18 66.0 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain ECH_2 PF16113.5 KFX98335.1 - 2.3e-126 421.8 0.0 3e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFX98335.1 - 2.2e-23 82.9 0.0 1e-22 80.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase zf-C2H2 PF00096.26 KFX98352.1 - 0.17 12.4 0.2 0.4 11.2 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type EAP30 PF04157.16 KFX98353.1 - 1.1e-71 240.9 0.0 1.2e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.19 KFX98354.1 - 2.9e-34 118.2 0.1 3.3e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HisKA_3 PF07730.13 KFX98355.1 - 0.0053 17.2 1.0 2.1 8.9 0.3 2.2 1 1 1 2 2 2 2 Histidine kinase Sec2p PF06428.11 KFX98355.1 - 0.022 14.7 0.6 0.022 14.7 0.6 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAR2 PF05282.11 KFX98356.1 - 2.5e-65 221.2 0.0 3.1e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.19 KFX98357.1 - 4e-46 155.9 1.3 4.9e-46 155.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFX98357.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) eIF-3c_N PF05470.12 KFX98358.1 - 1.4e-177 591.6 24.5 7.2e-145 483.6 4.0 3.1 2 1 1 3 3 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KFX98358.1 - 1e-13 51.7 0.6 5.4e-13 49.4 0.1 2.6 2 0 0 2 2 2 1 PCI domain PDH PF02153.17 KFX98358.1 - 4.4e-13 48.8 0.0 9.2e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KFX98358.1 - 3.8e-06 27.1 0.0 1.6e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX98358.1 - 9.7e-05 22.9 1.7 0.00045 20.7 0.0 2.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFX98358.1 - 0.0022 17.9 0.6 0.0068 16.3 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX98358.1 - 0.0039 17.3 0.8 0.93 9.5 0.0 3.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFX98358.1 - 0.0054 16.1 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFX98358.1 - 0.0078 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KFX98358.1 - 0.054 13.8 0.1 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain BSP_II PF05432.11 KFX98358.1 - 7.7 6.1 30.1 5.7 6.5 22.2 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RICTOR_N PF14664.6 KFX98359.1 - 1.9e-136 454.9 0.8 1.9e-136 454.9 0.8 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KFX98359.1 - 4.1e-38 130.1 0.8 1.9e-35 121.5 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KFX98359.1 - 5.7e-36 122.5 1.2 4.3e-33 113.2 0.1 4.6 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KFX98359.1 - 6e-32 109.7 0.9 3.3e-29 100.9 0.1 4.7 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KFX98359.1 - 1.3e-13 50.8 11.7 1.3e-13 50.8 11.7 2.1 2 0 0 2 2 2 1 Hr1 repeat Proteasom_PSMB PF10508.9 KFX98359.1 - 2.2e-06 26.5 1.7 0.041 12.4 0.0 4.9 4 1 1 5 5 5 2 Proteasome non-ATPase 26S subunit Uds1 PF15456.6 KFX98359.1 - 0.0054 16.9 2.4 0.02 15.1 2.4 2.0 1 0 0 1 1 1 1 Up-regulated During Septation HOOK PF05622.12 KFX98359.1 - 0.032 12.4 6.1 0.061 11.5 6.1 1.3 1 0 0 1 1 1 0 HOOK protein DUF4611 PF15387.6 KFX98359.1 - 0.12 12.6 1.2 18 5.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2443 PF10398.9 KFX98359.1 - 0.16 12.0 0.7 0.49 10.5 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) FAM76 PF16046.5 KFX98359.1 - 0.26 10.6 5.3 0.47 9.8 5.3 1.3 1 0 0 1 1 1 0 FAM76 protein Cep57_MT_bd PF06657.13 KFX98359.1 - 7.6 7.1 7.5 10 6.6 0.1 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KFX98359.1 - 8.8 7.1 8.7 2.5 8.9 4.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Uricase PF01014.18 KFX98360.1 - 3.7e-78 260.1 1.8 9.4e-41 139.1 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KFX98360.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.18 KFX98361.1 - 1.3e-41 141.7 0.0 2.8e-41 140.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 TPR_1 PF00515.28 KFX98362.1 - 3.9e-12 45.4 3.5 4.4e-05 23.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98362.1 - 1.8e-10 40.1 2.9 0.00081 19.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 KFX98362.1 - 7e-06 25.9 0.5 1.4e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 KFX98362.1 - 9.3e-06 25.5 0.1 0.012 15.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX98362.1 - 1.7e-05 25.0 0.0 0.0019 18.4 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98362.1 - 0.00043 20.1 0.0 0.0059 16.6 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98362.1 - 0.0024 17.5 2.7 0.0051 16.5 0.1 2.9 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.6 KFX98362.1 - 0.012 16.2 0.3 62 4.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98362.1 - 0.087 13.5 0.5 0.83 10.4 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Fibrillarin PF01269.17 KFX98363.1 - 3.1e-104 347.1 0.0 3.7e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KFX98363.1 - 1.9e-05 24.5 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFX98363.1 - 0.012 15.3 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KFX98363.1 - 0.026 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFX98363.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L11_N PF03946.14 KFX98364.1 - 1.4e-24 85.7 0.2 2.4e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFX98364.1 - 1.1e-16 61.0 0.3 1.9e-16 60.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 KFX98364.1 - 0.0042 16.9 0.3 0.14 11.9 0.0 2.5 1 1 1 2 2 2 2 Translation initiation factor IF-2, N-terminal region ROS_MUCR PF05443.11 KFX98364.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Glyco_transf_41 PF13844.6 KFX98365.1 - 6.3e-100 334.8 0.0 1.3e-52 178.8 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KFX98365.1 - 1.1e-17 63.0 8.4 0.00012 21.8 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98365.1 - 1.1e-14 53.3 11.9 0.0056 16.7 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98365.1 - 1e-12 47.5 13.7 0.0011 18.7 0.4 6.3 3 2 3 6 6 6 3 TPR repeat TPR_8 PF13181.6 KFX98365.1 - 5.8e-12 44.8 4.6 0.00071 19.6 0.2 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX98365.1 - 1.4e-11 43.9 9.0 0.018 14.9 0.2 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX98365.1 - 8.7e-10 38.8 10.6 0.00031 21.0 1.7 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98365.1 - 1.2e-09 37.5 3.5 0.0019 18.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX98365.1 - 2.9e-08 34.1 8.5 0.00023 21.6 1.0 3.6 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98365.1 - 6.5e-08 32.4 7.3 0.19 12.2 0.4 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98365.1 - 6.3e-07 29.7 8.1 0.1 13.5 0.0 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98365.1 - 7.7e-07 29.7 7.3 0.00033 21.2 0.2 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX98365.1 - 0.0011 19.1 0.3 0.054 13.7 0.2 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFX98365.1 - 0.0012 18.1 0.1 0.044 13.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KFX98365.1 - 0.0024 18.3 1.7 0.099 13.1 0.0 3.0 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KFX98365.1 - 0.028 14.6 4.5 0.16 12.1 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX98365.1 - 0.42 11.4 2.5 29 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CbeA_antitoxin PF06154.11 KFX98381.1 - 0.043 14.4 0.0 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A MFS_1 PF07690.16 KFX98382.1 - 1.1e-44 152.8 55.7 2.9e-44 151.4 54.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98382.1 - 6e-12 45.2 10.2 6e-12 45.2 10.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter HMA PF00403.26 KFX98383.1 - 2.5e-13 50.2 0.0 5.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KFX98383.1 - 1.3e-10 41.6 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zinc_ribbon_16 PF17034.5 KFX98384.1 - 1.4e-11 44.6 6.3 3.6e-11 43.4 6.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 KFX98384.1 - 0.0004 20.6 0.0 13 6.1 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 KFX98384.1 - 0.00089 18.8 7.8 0.003 17.1 7.8 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KFX98384.1 - 5.1 7.5 8.6 0.74 10.2 4.0 2.0 2 0 0 2 2 2 0 Ring finger domain Efg1 PF10153.9 KFX98385.1 - 3.4e-38 130.5 9.7 3.4e-38 130.5 9.7 1.8 2 1 0 2 2 2 1 rRNA-processing protein Efg1 Type2_restr_D3 PF16902.5 KFX98385.1 - 0.052 13.5 0.7 0.17 11.8 0.7 1.8 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Mrpl_C PF18502.1 KFX98385.1 - 0.95 9.8 5.3 0.7 10.2 0.9 2.4 1 1 1 2 2 2 0 54S ribosomal protein L8 C-terminal domain SH3-RhoG_link PF16609.5 KFX98385.1 - 0.96 9.1 6.5 0.22 11.2 2.0 2.1 1 1 0 2 2 2 0 SH3-RhoGEF linking unstructured region Asp-B-Hydro_N PF05279.11 KFX98385.1 - 2.4 8.2 10.7 1.9 8.5 9.1 1.6 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region dsrm PF00035.26 KFX98386.1 - 3.8e-05 24.3 0.0 0.00013 22.6 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif TANGO2 PF05742.12 KFX98387.1 - 9.4e-73 245.4 0.0 1.1e-72 245.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Tfb2 PF03849.14 KFX98389.1 - 6.6e-137 456.2 0.0 9.2e-137 455.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KFX98389.1 - 2.4e-23 82.3 0.5 4.3e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KFX98389.1 - 3e-05 24.2 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 KFX98390.1 - 2.9e-14 53.1 0.2 5.2e-14 52.3 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KFX98390.1 - 4.1e-05 23.7 0.0 5.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Homeodomain PF00046.29 KFX98392.1 - 3.5e-17 62.0 3.4 7.1e-17 61.0 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFX98392.1 - 0.046 13.6 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain GEN1_C PF18380.1 KFX98392.1 - 2.4 9.1 6.0 0.47 11.4 1.5 2.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain 3HCDH_N PF02737.18 KFX98393.1 - 6.6e-51 172.7 0.2 8.5e-51 172.4 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFX98393.1 - 1.6e-33 115.2 0.0 3.3e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFX98393.1 - 0.003 17.7 0.1 0.0057 16.8 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX98393.1 - 0.021 15.1 0.2 0.057 13.7 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KFX98393.1 - 0.022 14.4 0.3 0.032 13.8 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFX98393.1 - 0.028 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIMELESS PF04821.14 KFX98394.1 - 1.2e-87 293.7 0.0 2.7e-87 292.6 0.0 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KFX98394.1 - 3e-30 105.9 10.0 3e-30 105.9 10.0 3.2 2 1 0 2 2 2 1 Timeless protein C terminal region DUF3388 PF11868.8 KFX98394.1 - 0.0036 16.7 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) DALR_2 PF09190.11 KFX98394.1 - 0.0075 16.7 0.3 0.043 14.3 0.2 2.3 2 0 0 2 2 2 1 DALR domain UCMA PF17085.5 KFX98394.1 - 1.1 9.2 8.2 5.1 7.1 8.2 2.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein KAP PF05804.12 KFX98395.1 - 0.00014 20.2 0.0 0.018 13.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KFX98395.1 - 0.05 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Arm PF00514.23 KFX98395.1 - 0.061 13.4 0.1 57 4.0 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 KFX98395.1 - 0.14 12.4 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 CDRN PF05174.12 KFX98395.1 - 0.37 10.5 4.5 16 5.3 0.0 3.9 4 0 0 4 4 4 0 Cysteine-rich D. radiodurans N terminus DPM3 PF08285.11 KFX98396.1 - 9.9e-36 121.8 0.1 1.3e-35 121.4 0.1 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) MSA-2c PF12238.8 KFX98396.1 - 7.2 6.6 9.0 10 6.1 9.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CENP-P PF13096.6 KFX98397.1 - 0.0085 15.8 0.0 0.0087 15.8 0.0 1.0 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Helicase_C PF00271.31 KFX98401.1 - 3.3e-12 46.7 0.0 5.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Oxysterol_BP PF01237.18 KFX98404.1 - 1.7e-12 46.9 0.0 1.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein K_channel_TID PF07941.11 KFX98414.1 - 1.6 9.2 10.3 0.23 12.0 4.4 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1748 PF08520.10 KFX98430.1 - 5.3e-34 115.9 0.1 6.3e-34 115.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) SE PF08491.10 KFX98436.1 - 6.9e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KFX98436.1 - 3.9e-08 33.3 0.3 1.7e-05 24.6 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX98436.1 - 1.2e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX98436.1 - 5.3e-07 29.2 0.0 8.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KFX98436.1 - 3.2e-06 26.5 0.1 0.00075 18.7 0.2 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX98436.1 - 2.1e-05 23.8 1.1 3.6e-05 23.0 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFX98436.1 - 9.9e-05 22.5 0.2 0.0017 18.5 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain PPR_3 PF13812.6 KFX98436.1 - 0.00063 19.8 0.0 0.039 14.0 0.0 3.1 4 0 0 4 4 3 1 Pentatricopeptide repeat domain Thi4 PF01946.17 KFX98436.1 - 0.0019 17.5 0.0 0.0062 15.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family PPR_2 PF13041.6 KFX98436.1 - 0.004 17.3 0.0 0.021 15.0 0.0 2.3 3 0 0 3 3 2 1 PPR repeat family Pyr_redox_2 PF07992.14 KFX98436.1 - 0.0059 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX98436.1 - 0.008 14.9 0.2 0.014 14.1 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX98436.1 - 0.016 14.5 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KFX98436.1 - 0.019 13.8 0.1 0.94 8.3 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KFX98436.1 - 0.042 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KFX98436.1 - 0.057 14.0 2.8 0.073 13.6 0.2 2.6 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Fic PF02661.18 KFX98437.1 - 1.1e-15 58.2 0.0 2.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Ribonuc_L-PSP PF01042.21 KFX98438.1 - 4.3e-25 88.1 0.0 5.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mito_carr PF00153.27 KFX98439.1 - 1.6e-63 210.6 5.3 1.7e-20 72.7 0.9 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein EIF_2_alpha PF07541.12 KFX98440.1 - 2.9e-36 124.1 0.0 5.2e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFX98440.1 - 5.2e-13 49.1 1.0 1.1e-12 48.1 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S24 PF00717.23 KFX98440.1 - 0.00055 19.8 0.5 0.0075 16.2 0.0 2.9 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFX98440.1 - 0.0028 17.5 0.0 0.03 14.1 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Bacteriocin_IIi PF11758.8 KFX98440.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin cNMP_binding PF00027.29 KFX98441.1 - 1.1e-30 105.5 0.2 5.1e-18 64.9 0.0 5.4 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFX98441.1 - 6.6e-17 62.4 7.1 9.6e-16 58.6 6.1 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase Sugar_tr PF00083.24 KFX98443.1 - 3.4e-75 253.6 16.7 3.5e-74 250.3 16.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98443.1 - 2.7e-16 59.4 26.5 1.1e-14 54.1 22.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 KFX98443.1 - 0.42 10.7 0.0 0.42 10.7 0.0 3.3 3 1 0 3 3 3 0 Cell division protein CrgA MFS_1 PF07690.16 KFX98446.1 - 1.5e-23 83.3 39.7 2.2e-22 79.5 39.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Lon_C PF05362.13 KFX98446.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain CoatB PF10389.9 KFX98446.1 - 2.7 7.9 7.8 0.18 11.7 1.2 2.4 3 0 0 3 3 3 0 Bacteriophage coat protein B Phage_holin_3_1 PF05106.12 KFX98447.1 - 0.12 12.8 0.3 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) EOS1 PF12326.8 KFX98447.1 - 1.1 9.2 5.5 0.2 11.6 0.8 2.2 2 0 0 2 2 2 0 N-glycosylation protein CPSF_A PF03178.15 KFX98448.1 - 2.9e-90 302.8 0.0 8.4e-90 301.3 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KFX98448.1 - 8.4e-22 77.4 0.0 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PBP1_TM PF14812.6 KFX98448.1 - 9.4 6.7 7.2 0.39 11.1 0.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LMBR1 PF04791.16 KFX98449.1 - 4.7e-18 65.4 7.3 4.7e-18 65.4 7.3 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF3611 PF12263.8 KFX98449.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3611) Fungal_trans PF04082.18 KFX98450.1 - 1e-13 50.9 0.2 2e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98450.1 - 1.8e-05 24.7 12.5 3.1e-05 24.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_6 PF01341.17 KFX98451.1 - 8.1e-96 321.3 0.4 1e-95 321.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_114 PF03537.13 KFX98452.1 - 5.5e-81 271.3 0.3 8e-81 270.7 0.3 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Abhydrolase_6 PF12697.7 KFX98452.1 - 4.7e-10 40.5 1.4 1.1e-09 39.2 0.5 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX98452.1 - 2.2e-09 37.3 0.1 1.5e-07 31.3 0.0 3.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX98452.1 - 1.9e-05 24.0 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KFX98452.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region ApbA_C PF08546.11 KFX98453.1 - 7.8e-25 87.5 0.0 1.6e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFX98453.1 - 6.2e-24 84.4 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 KFX98453.1 - 0.003 17.6 12.1 0.0051 16.9 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S21e PF01249.18 KFX98454.1 - 3e-37 126.6 0.1 3.5e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.10 KFX98455.1 - 2e-23 82.1 0.0 4e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Ish1 PF10281.9 KFX98455.1 - 0.054 13.8 0.1 0.55 10.6 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Aldo_ket_red PF00248.21 KFX98456.1 - 9.3e-41 139.9 0.0 1.6e-38 132.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Bax1-I PF01027.20 KFX98457.1 - 2.5e-35 122.2 12.6 2.5e-35 122.2 12.6 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 SnoaL_4 PF13577.6 KFX98460.1 - 5.3e-22 78.3 0.0 6.2e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFX98460.1 - 0.053 13.9 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Scytalone_dh PF02982.14 KFX98460.1 - 0.054 13.3 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Scytalone dehydratase SnoaL_2 PF12680.7 KFX98460.1 - 0.06 14.0 0.1 0.1 13.3 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain NOG1_N PF17835.1 KFX98462.1 - 3e-49 167.1 0.7 1.1e-48 165.3 0.1 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KFX98462.1 - 9.8e-28 95.9 4.5 1.1e-27 95.8 3.0 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 KFX98462.1 - 1.1e-25 89.2 0.4 2.3e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KFX98462.1 - 1.9e-15 56.9 0.0 4.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX98462.1 - 3.4e-08 33.2 0.0 8.6e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFX98462.1 - 0.0019 18.6 0.4 0.1 13.0 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX98462.1 - 0.0024 17.8 0.1 0.43 10.5 0.0 3.0 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KFX98462.1 - 0.027 14.5 0.0 7.2 6.6 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AAA_33 PF13671.6 KFX98462.1 - 3 8.0 6.5 40 4.3 1.3 3.5 4 0 0 4 4 4 0 AAA domain Asp_protease PF09668.10 KFX98463.1 - 2.4e-62 208.3 0.2 3.5e-62 207.7 0.2 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX98463.1 - 4.5e-24 84.8 0.0 8.9e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFX98463.1 - 2e-11 44.3 0.0 4.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 KFX98463.1 - 1e-08 34.9 0.1 2.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 KFX98463.1 - 0.00023 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 KFX98463.1 - 0.0026 18.0 0.0 0.0075 16.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 KFX98463.1 - 0.023 14.5 1.6 0.04 13.7 0.3 2.0 2 0 0 2 2 2 0 UBA-like domain RuvA_C PF07499.13 KFX98463.1 - 0.14 12.6 0.0 0.45 11.0 0.0 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain Methyltransf_8 PF05148.15 KFX98464.1 - 5.6e-55 186.6 0.0 5.7e-53 180.0 0.0 2.9 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KFX98464.1 - 7.2e-06 26.6 0.0 4.2e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98464.1 - 5.3e-05 23.8 0.0 0.012 16.3 0.0 2.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFX98464.1 - 0.0067 16.4 0.0 0.0067 16.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98464.1 - 0.014 15.2 0.1 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFX98464.1 - 0.069 12.7 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Fungal_trans_2 PF11951.8 KFX98465.1 - 4e-20 72.0 1.4 1e-12 47.6 1.0 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98465.1 - 1.7e-07 31.2 10.7 2.9e-07 30.5 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FidL_like PF15941.5 KFX98465.1 - 0.088 13.3 1.5 0.32 11.5 1.5 2.0 1 0 0 1 1 1 0 FidL-like putative membrane protein Proteasome PF00227.26 KFX98466.1 - 1e-56 191.4 0.1 1.3e-56 191.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX98466.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KFX98467.1 - 1.7e-65 221.7 0.0 3.3e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFX98467.1 - 2.2e-61 208.0 8.0 2.2e-61 208.0 8.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal TipAS PF07739.13 KFX98467.1 - 0.083 13.4 0.5 2 9.0 0.0 2.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Sel1 PF08238.12 KFX98469.1 - 5.2e-15 55.6 7.6 0.00014 22.5 0.3 3.4 3 0 0 3 3 3 3 Sel1 repeat HEAT PF02985.22 KFX98471.1 - 9e-06 25.5 2.6 0.79 10.1 0.1 6.1 8 1 1 9 9 9 1 HEAT repeat CLASP_N PF12348.8 KFX98471.1 - 0.00011 21.8 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 KFX98471.1 - 0.00032 20.8 0.0 0.4 10.7 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 KFX98471.1 - 0.0033 17.1 0.6 1 8.9 0.1 2.9 3 1 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II IFRD PF05004.13 KFX98471.1 - 0.0045 16.1 1.0 0.01 15.0 0.0 2.0 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) TAN PF11640.8 KFX98471.1 - 0.0047 17.1 0.1 0.016 15.4 0.1 2.0 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 KFX98471.1 - 0.0094 16.4 4.8 4.8 7.8 0.2 4.6 5 1 0 5 5 5 2 HEAT-like repeat GCFC PF07842.12 KFX98472.1 - 4.6e-78 262.6 3.8 4.6e-78 262.6 3.8 1.7 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFX98472.1 - 6.5e-15 54.7 4.5 2.1e-14 53.1 4.5 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFX98472.1 - 1.4e-11 44.6 6.9 1.4e-11 44.6 6.9 2.8 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KFX98472.1 - 4.3e-07 29.9 3.0 4.3e-07 29.9 3.0 2.9 3 2 0 3 3 3 1 G-patch domain ATP-synt_E PF05680.12 KFX98472.1 - 4.3 7.7 7.0 0.77 10.1 1.8 2.4 2 0 0 2 2 2 0 ATP synthase E chain PH_10 PF15411.6 KFX98473.1 - 1.2e-40 138.6 0.3 2.2e-40 137.8 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KFX98473.1 - 8.4e-31 106.1 0.1 1.6e-30 105.2 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KFX98473.1 - 4.2e-28 98.8 0.0 6.8e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KFX98473.1 - 2e-08 34.1 0.0 5.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 KFX98474.1 - 6.4e-30 102.8 6.8 5.7e-05 23.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KFX98474.1 - 3.7e-05 23.5 0.2 8.5e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFX98474.1 - 0.00011 22.4 0.2 0.8 10.1 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFX98474.1 - 0.00024 20.9 0.1 0.00058 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KFX98474.1 - 0.0025 16.5 0.0 0.14 10.7 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 F-box_4 PF15966.5 KFX98474.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 F-box Nucleoporin_N PF08801.11 KFX98474.1 - 0.22 10.2 0.0 0.75 8.5 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like TFIIA PF03153.13 KFX98474.1 - 0.32 10.9 20.1 0.61 10.0 20.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 KFX98474.1 - 2.4 7.2 27.1 3.6 6.7 27.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRF PF01765.19 KFX98480.1 - 9.6e-12 45.2 0.0 1.9e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Ribosome recycling factor Mitofilin PF09731.9 KFX98482.1 - 4.9e-72 243.7 1.2 5.3e-72 243.6 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4363 PF14276.6 KFX98482.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) ArnB_C PF18677.1 KFX98482.1 - 0.078 13.1 0.4 0.42 10.7 0.3 2.0 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain Mur_ligase_C PF02875.21 KFX98483.1 - 0.0008 19.6 0.0 0.003 17.8 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KFX98483.1 - 0.0018 18.3 0.2 0.085 12.8 0.2 2.8 1 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_M PF08245.12 KFX98484.1 - 7.4e-07 29.4 0.1 4.2e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Mur ligase middle domain USP7_C2 PF14533.6 KFX98484.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal Fungal_trans_2 PF11951.8 KFX98487.1 - 3e-09 36.2 4.7 4.2e-09 35.7 4.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98487.1 - 8.6e-09 35.4 6.9 1.4e-08 34.7 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KFX98488.1 - 2.2e-58 197.3 4.0 3.2e-58 196.7 4.0 1.2 1 0 0 1 1 1 1 RTA1 like protein UCR_UQCRX_QCR9 PF05365.12 KFX98488.1 - 0.048 13.6 0.4 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like FTA4 PF13093.6 KFX98489.1 - 6.9e-56 189.3 0.9 8.1e-56 189.1 0.9 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 COG2 PF06148.11 KFX98489.1 - 0.11 12.6 1.6 0.18 11.9 0.5 1.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 KFX98489.1 - 4.8 7.7 5.7 1.7 9.2 0.2 2.7 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Acyl-CoA_dh_1 PF00441.24 KFX98490.1 - 3.1e-31 108.6 2.7 4.8e-31 108.0 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KFX98490.1 - 6.4e-22 77.5 0.2 2.1e-21 75.9 0.2 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KFX98490.1 - 1.4e-16 60.4 0.4 2.8e-16 59.5 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX98490.1 - 1.7e-10 41.6 0.3 2.2e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFX98490.1 - 2.6e-08 34.2 0.3 6.1e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNCAIP_SNCA_bd PF16700.5 KFX98490.1 - 0.025 14.3 0.5 0.053 13.2 0.1 1.7 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF572 PF04502.13 KFX98492.1 - 2.6e-69 234.4 7.8 3.1e-69 234.2 7.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) GrpB PF04229.14 KFX98492.1 - 0.066 13.4 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 GrpB protein zf-ACC PF17848.1 KFX98492.1 - 0.76 9.9 3.4 4.3 7.5 0.7 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF2737 PF10930.8 KFX98506.1 - 0.23 11.1 1.2 0.83 9.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2737) AMP-binding PF00501.28 KFX98521.1 - 5.4e-75 252.6 0.0 6.9e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX98521.1 - 5.9e-13 49.6 0.1 1.3e-12 48.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.15 KFX98521.1 - 0.2 11.2 0.0 0.93 9.0 0.0 2.0 2 0 0 2 2 2 0 Autoinducer binding domain DUF2236 PF09995.9 KFX98522.1 - 3e-29 102.8 0.2 4.5e-29 102.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.8 KFX98522.1 - 1e-28 100.1 0.8 2e-28 99.2 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) SKG6 PF08693.10 KFX98522.1 - 0.24 10.8 0.7 0.62 9.5 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3149 PF11346.8 KFX98522.1 - 2.8 7.6 4.5 6.6 6.4 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF2880 PF11082.8 KFX98523.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2880) DUF3425 PF11905.8 KFX98524.1 - 1.9e-19 69.9 2.0 5.7e-19 68.3 2.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFX98524.1 - 0.00014 21.9 11.5 0.0011 19.0 11.5 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX98524.1 - 0.43 10.7 12.2 6.4 6.9 7.7 2.6 2 0 0 2 2 2 0 Basic region leucine zipper ADH_N_2 PF16884.5 KFX98525.1 - 9.9e-32 109.1 0.0 2.5e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFX98525.1 - 1.2e-21 77.1 0.0 2.4e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX98525.1 - 3e-07 31.6 0.0 9e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AMP-binding PF00501.28 KFX98526.1 - 3.2e-75 253.3 0.0 5.4e-75 252.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KFX98526.1 - 6e-59 199.3 0.0 1.4e-58 198.1 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFX98526.1 - 1.8e-53 180.9 2.0 3.4e-53 180.0 2.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98526.1 - 4.2e-43 147.6 0.6 7.8e-43 146.7 0.6 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX98526.1 - 1.6e-19 70.5 1.7 1.7e-16 60.6 0.6 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KFX98526.1 - 2.1e-17 63.4 1.1 7.3e-11 42.0 0.0 3.7 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX98526.1 - 1.6e-11 44.3 0.0 4.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KFX98526.1 - 1.8e-10 40.3 0.2 9e-07 28.2 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX98526.1 - 2.4e-06 26.9 1.0 0.001 18.2 0.0 2.9 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFX98526.1 - 3.4e-05 23.1 2.5 0.005 16.0 0.3 3.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFX98526.1 - 3.5e-05 23.8 5.6 0.00064 19.7 1.4 3.8 3 2 1 4 4 4 1 NAD(P)H-binding AMP-binding_C PF13193.6 KFX98526.1 - 0.00014 22.8 0.1 0.00089 20.2 0.1 2.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KFX98526.1 - 0.0078 15.7 0.0 0.7 9.2 0.0 2.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KFX98526.1 - 0.01 15.2 0.2 0.025 13.9 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Wax2_C PF12076.8 KFX98526.1 - 0.033 13.9 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 WAX2 C-terminal domain DFP PF04127.15 KFX98526.1 - 0.084 12.7 0.6 0.2 11.5 0.6 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 KFX98526.1 - 0.28 10.7 3.0 4.1 6.9 1.7 3.0 3 0 0 3 3 3 0 NmrA-like family 3HCDH_N PF02737.18 KFX98526.1 - 1.1 9.2 4.1 0.58 10.0 0.5 2.4 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KFX98527.1 - 4.3e-32 111.8 0.0 5.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX98527.1 - 1.4e-15 57.3 0.0 2.9e-14 52.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX98527.1 - 4.1e-05 24.3 0.0 8.8e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 KFX98527.1 - 0.0032 16.3 0.0 0.0051 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_2 PF02230.16 KFX98527.1 - 0.0069 16.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 KFX98527.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family LIP PF03583.14 KFX98527.1 - 0.048 13.0 0.1 0.088 12.1 0.0 1.4 2 0 0 2 2 2 0 Secretory lipase MFS_1 PF07690.16 KFX98528.1 - 8.1e-36 123.7 34.5 1.6e-35 122.7 33.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX98528.1 - 0.0007 19.0 7.7 0.0007 19.0 7.7 2.6 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ESSS PF10183.9 KFX98528.1 - 0.031 14.5 0.5 0.7 10.1 0.0 3.2 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NAD_binding_8 PF13450.6 KFX98530.1 - 0.00037 20.7 0.2 0.00081 19.6 0.1 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX98530.1 - 0.0041 16.7 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX98530.1 - 0.019 15.0 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KFX98530.1 - 0.075 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KFX98530.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX98530.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX98530.1 - 0.16 11.2 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Phage_holin_3_7 PF05449.11 KFX98540.1 - 0.024 14.7 0.4 0.032 14.3 0.4 1.2 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 p450 PF00067.22 KFX98541.1 - 1.8e-51 175.3 0.0 2.5e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.22 KFX98542.1 - 7.6e-17 61.3 1.3 1.2e-16 60.7 1.3 1.2 1 0 0 1 1 1 1 Cupin tify PF06200.14 KFX98542.1 - 0.0085 15.4 0.4 0.019 14.3 0.4 1.5 1 0 0 1 1 1 1 tify domain MFS_1 PF07690.16 KFX98546.1 - 1.2e-38 133.0 27.0 1.2e-38 133.0 27.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KFX98547.1 - 8e-07 29.1 10.4 1.2e-06 28.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX98547.1 - 5.6e-06 25.6 0.3 1.3e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_11 PF14833.6 KFX98548.1 - 5.8e-69 230.0 2.7 4.3e-34 117.4 0.0 2.7 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KFX98548.1 - 2.5e-66 222.7 6.1 5e-34 117.8 4.3 2.7 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase SBD_N PF07005.11 KFX98548.1 - 6e-59 199.5 0.1 1e-58 198.8 0.1 1.4 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 KFX98548.1 - 3.5e-38 131.8 0.4 1.8e-37 129.5 0.4 2.4 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain F420_oxidored PF03807.17 KFX98548.1 - 1.7e-11 44.5 1.9 3.7e-05 24.2 1.0 3.2 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Cellulase PF00150.18 KFX98548.1 - 6.9e-10 38.8 0.0 6.9e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) 3HCDH_N PF02737.18 KFX98548.1 - 3.1e-08 33.7 2.9 0.0029 17.5 1.4 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX98548.1 - 0.00014 21.2 0.1 0.011 15.1 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX98548.1 - 0.00033 20.3 4.4 2.5 7.7 1.9 4.3 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFX98548.1 - 0.002 17.8 1.3 0.46 10.1 0.0 2.6 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF4246 PF14033.6 KFX98549.1 - 3.4e-143 478.0 0.0 3.9e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Pectate_lyase_3 PF12708.7 KFX98550.1 - 1.2e-75 254.0 10.1 2.8e-64 216.9 3.8 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX98550.1 - 2e-05 24.2 0.5 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ank_2 PF12796.7 KFX98553.1 - 3.7e-20 72.3 0.2 6.3e-10 39.5 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX98553.1 - 2.1e-17 63.0 0.0 2.1e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 KFX98553.1 - 8.4e-16 58.3 0.3 2.4e-06 27.5 0.1 3.6 3 0 0 3 3 3 3 NACHT domain Ank_4 PF13637.6 KFX98553.1 - 3.5e-12 46.6 0.0 0.00031 21.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX98553.1 - 8.5e-12 45.0 2.3 9e-06 25.9 0.0 5.9 6 0 0 6 6 5 1 Ankyrin repeat Ank_3 PF13606.6 KFX98553.1 - 3.1e-11 42.5 1.2 0.048 14.2 0.0 6.5 6 1 1 7 7 4 2 Ankyrin repeat AAA_16 PF13191.6 KFX98553.1 - 1e-09 39.0 0.3 8.9e-05 22.9 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFX98553.1 - 2.3e-08 34.4 0.2 0.011 16.0 0.1 3.6 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFX98553.1 - 4.5e-07 30.2 0.0 0.0088 16.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NB-ARC PF00931.22 KFX98553.1 - 4.2e-05 22.9 0.0 0.29 10.3 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain DUF676 PF05057.14 KFX98553.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KFX98553.1 - 0.00022 20.6 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_33 PF13671.6 KFX98553.1 - 0.00028 21.1 0.1 0.0042 17.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KFX98553.1 - 0.00066 20.2 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KFX98553.1 - 0.0012 19.2 0.0 0.6 10.5 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFX98553.1 - 0.0013 18.7 0.0 1.4 9.0 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Abhydrolase_6 PF12697.7 KFX98553.1 - 0.0018 18.9 0.0 0.0037 17.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family APS_kinase PF01583.20 KFX98553.1 - 0.0021 18.0 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.6 KFX98553.1 - 0.0026 18.3 0.0 0.019 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFX98553.1 - 0.025 14.9 0.0 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KFX98553.1 - 0.038 13.9 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 KFX98553.1 - 0.039 13.5 0.0 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 KFX98553.1 - 0.059 13.1 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Ploopntkinase3 PF18751.1 KFX98553.1 - 0.065 13.1 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 KFX98553.1 - 0.11 11.8 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KFX98553.1 - 0.11 11.7 0.0 2.7 7.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) PGAP1 PF07819.13 KFX98553.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_30 PF13604.6 KFX98553.1 - 0.18 11.5 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KFX98553.1 - 0.19 11.0 1.4 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 KFX98553.1 - 0.19 11.0 0.0 0.57 9.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin FAD_binding_3 PF01494.19 KFX98554.1 - 1.1e-23 84.0 0.0 5.9e-23 81.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX98554.1 - 1.3e-10 41.4 3.6 9.9e-05 22.1 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX98554.1 - 8.8e-10 38.3 0.6 3e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX98554.1 - 1.6e-07 30.8 0.6 1.9e-06 27.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFX98554.1 - 8.8e-07 29.4 0.5 0.067 13.8 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX98554.1 - 2e-06 27.5 0.5 4.5e-06 26.3 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX98554.1 - 1.4e-05 24.0 1.0 0.0001 21.2 1.0 2.1 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KFX98554.1 - 0.00012 22.3 0.2 0.00027 21.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KFX98554.1 - 0.00091 18.2 1.6 0.012 14.5 0.1 2.4 2 1 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.22 KFX98554.1 - 0.0017 17.5 0.5 0.0026 16.9 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 KFX98554.1 - 0.026 13.6 0.0 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 KFX98554.1 - 0.036 13.3 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KFX98554.1 - 0.095 11.7 0.2 0.49 9.4 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFX98554.1 - 0.096 11.9 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyoxalase PF00903.25 KFX98555.1 - 2.1e-14 53.8 0.1 3.1e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX98555.1 - 0.00015 22.0 0.1 0.00028 21.1 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFX98555.1 - 0.0022 18.7 0.0 0.0053 17.5 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain TAP42 PF04177.12 KFX98556.1 - 4e-101 338.3 0.0 4.5e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family RE_EcoO109I PF14511.6 KFX98556.1 - 0.00041 20.0 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Type II restriction endonuclease EcoO109I HAT PF02184.16 KFX98556.1 - 0.18 11.8 0.4 0.37 10.8 0.4 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat APG6_N PF17675.1 KFX98556.1 - 0.25 11.9 2.8 0.41 11.2 0.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribonuclease_3 PF00636.26 KFX98557.1 - 1.1e-39 135.3 0.0 2.8e-19 69.7 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.14 KFX98557.1 - 6.8e-24 83.8 0.2 1.6e-22 79.5 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KFX98557.1 - 2e-21 76.5 0.0 2.8e-09 37.2 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 KFX98557.1 - 1.3e-16 60.9 0.1 3.7e-16 59.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX98557.1 - 2.1e-15 57.1 0.1 9.3e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX98557.1 - 2.4e-11 43.7 0.0 4.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KFX98557.1 - 0.0023 18.6 0.0 1.3 9.8 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif CPSase_L_D2 PF02786.17 KFX98558.1 - 9e-113 375.0 0.2 1.8e-84 282.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFX98558.1 - 1.3e-46 157.6 0.0 2.6e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KFX98558.1 - 1.5e-45 155.3 0.0 3.4e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KFX98558.1 - 4.8e-44 150.0 0.0 1.3e-43 148.5 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KFX98558.1 - 7e-41 139.4 0.1 1.8e-40 138.1 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KFX98558.1 - 3.4e-29 101.9 0.0 7.7e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KFX98558.1 - 7.8e-21 74.1 0.0 4.4e-20 71.7 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KFX98558.1 - 4.7e-17 62.2 0.8 1.4e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX98558.1 - 1.1e-14 54.4 0.1 8.7e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFX98558.1 - 3.6e-09 36.5 0.0 0.00059 19.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KFX98558.1 - 2.7e-05 24.0 1.7 0.0018 18.1 0.6 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KFX98558.1 - 6.3e-05 23.1 0.4 0.18 11.9 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KFX98558.1 - 0.00029 20.7 0.3 0.17 11.6 0.0 4.3 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 KFX98558.1 - 0.00087 19.1 0.4 1.9 8.2 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pkinase PF00069.25 KFX98559.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 KFX98559.1 - 0.043 13.2 0.0 0.49 9.7 0.0 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hamartin PF04388.12 KFX98562.1 - 4.7e-19 68.6 37.1 4.7e-19 68.6 37.1 4.1 1 1 0 2 2 2 1 Hamartin protein RACo_linker PF17650.1 KFX98562.1 - 0.0027 17.5 2.1 0.032 14.1 0.4 2.7 2 0 0 2 2 2 1 RACo linker region DUF5624 PF18538.1 KFX98562.1 - 0.069 13.2 0.4 0.29 11.2 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) PilM_2 PF11104.8 KFX98562.1 - 1.7 7.6 9.2 0.033 13.2 0.5 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Pex2_Pex12 PF04757.14 KFX98563.1 - 1.5e-51 175.1 3.3 1.9e-51 174.8 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KFX98563.1 - 0.00014 21.9 2.8 0.00025 21.1 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFX98563.1 - 0.0027 17.7 2.1 0.0047 16.9 2.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFX98563.1 - 0.0034 17.2 1.6 0.0055 16.5 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX98563.1 - 0.014 15.2 2.9 0.024 14.5 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX98563.1 - 0.018 15.4 3.2 0.031 14.6 3.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFX98563.1 - 0.024 14.5 3.1 0.045 13.6 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L23 PF00276.20 KFX98564.1 - 2.8e-13 50.0 0.0 5.4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.14 KFX98565.1 - 1.2e-25 90.4 0.0 6.8e-18 65.2 0.0 2.2 1 1 1 2 2 2 2 MT-A70 Mito_carr PF00153.27 KFX98566.1 - 8e-66 218.0 0.8 4.4e-23 81.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX98566.1 - 0.056 12.6 0.3 3.2 6.8 0.0 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Ferritin_2 PF13668.6 KFX98567.1 - 3.4e-12 46.7 0.0 6.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Hist_deacetyl PF00850.19 KFX98568.1 - 4.4e-77 259.6 0.0 5.8e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Npa1 PF11707.8 KFX98569.1 - 5.5e-100 335.0 0.0 1.5e-99 333.6 0.0 1.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFX98569.1 - 2.1e-54 184.2 1.4 8.5e-54 182.2 1.3 2.2 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Longin PF13774.6 KFX98569.1 - 1.4e-28 98.8 0.0 3.8e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFX98569.1 - 6.6e-15 54.7 0.1 1.6e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Arm PF00514.23 KFX98569.1 - 0.00052 20.0 0.5 0.0052 16.8 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Creb_binding PF09030.10 KFX98569.1 - 0.0064 17.2 0.2 0.028 15.1 0.0 2.2 2 0 0 2 2 2 1 Creb binding SUV3_C PF12513.8 KFX98570.1 - 3.2e-19 68.6 0.1 3.2e-19 68.6 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFX98570.1 - 3e-11 43.6 0.0 6.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KFX98570.1 - 2.5e-06 27.3 0.2 5.9e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Chromo PF00385.24 KFX98571.1 - 0.0064 16.4 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CRAL_TRIO PF00650.20 KFX98572.1 - 5.1e-26 91.3 0.0 7.4e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX98572.1 - 1.4e-10 41.2 0.2 3.4e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AIF_C PF14721.6 KFX98572.1 - 0.057 13.8 0.1 0.19 12.1 0.1 1.9 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rad4 PF03835.15 KFX98573.1 - 2e-33 115.2 0.2 6.4e-33 113.5 0.2 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFX98573.1 - 4e-28 97.6 0.1 8.5e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KFX98573.1 - 6e-17 61.2 0.3 1.8e-16 59.7 0.3 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFX98573.1 - 1e-15 58.4 0.7 1e-15 58.4 0.7 4.6 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 CorA PF01544.18 KFX98573.1 - 5.3e-13 48.9 3.4 8e-11 41.8 0.6 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Transglut_core PF01841.19 KFX98573.1 - 0.022 15.2 0.0 0.077 13.4 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2207 PF09972.9 KFX98573.1 - 0.13 11.0 0.1 0.24 10.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-AN1 PF01428.16 KFX98574.1 - 1.7e-23 82.5 23.2 6.6e-12 45.4 8.2 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 KFX98574.1 - 0.00071 19.9 6.8 0.26 11.7 0.8 2.5 2 0 0 2 2 2 2 C5HC2 zinc finger IBR PF01485.21 KFX98574.1 - 0.0086 16.3 16.6 0.018 15.2 4.2 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.12 KFX98574.1 - 5.1 7.4 12.2 4.9 7.5 4.9 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain Transp_Tc5_C PF04236.15 KFX98574.1 - 9.6 6.6 13.6 7.4 7.0 1.1 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HIT PF01230.23 KFX98575.1 - 5.9e-13 49.4 0.0 1.7e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFX98575.1 - 0.0041 17.6 0.1 0.036 14.6 0.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFX98575.1 - 0.013 15.4 1.0 0.042 13.7 0.0 2.1 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 ATP19 PF11022.8 KFX98576.1 - 3.3e-24 85.0 0.0 4.4e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit K tRNA-synt_1c PF00749.21 KFX98579.1 - 5e-100 334.4 0.1 6.7e-100 334.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFX98579.1 - 1.1e-37 129.6 0.4 2.3e-37 128.5 0.3 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KFX98579.1 - 0.0076 15.6 0.6 0.025 14.0 0.7 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DSS1_SEM1 PF05160.13 KFX98579.1 - 0.099 12.7 2.5 0.3 11.2 2.5 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family GST_C_2 PF13410.6 KFX98579.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box PF00646.33 KFX98580.1 - 0.002 17.9 0.4 0.0044 16.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX98580.1 - 0.018 14.9 0.3 0.048 13.5 0.3 1.7 1 0 0 1 1 1 0 F-box-like Paramecium_SA PF01508.16 KFX98582.1 - 4.1 7.9 14.2 0.14 12.6 2.0 2.8 2 1 0 2 2 2 0 Paramecium surface antigen domain Fungal_trans_2 PF11951.8 KFX98583.1 - 1.9e-29 102.7 9.6 3.7e-29 101.7 9.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 KFX98583.1 - 9.1e-27 94.6 0.1 4.8e-26 92.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Zn_clus PF00172.18 KFX98583.1 - 0.00021 21.4 3.4 0.00047 20.2 3.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.27 KFX98583.1 - 0.0012 19.4 0.7 0.0029 18.1 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX98583.1 - 0.0032 16.8 0.1 0.0059 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX98583.1 - 0.061 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aminotran_4 PF01063.19 KFX98584.1 - 5.2e-43 147.5 0.0 6.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF2254 PF10011.9 KFX98584.1 - 0.25 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Aldo_ket_red PF00248.21 KFX98585.1 - 3.6e-65 220.1 0.0 4.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YCF90 PF17088.5 KFX98585.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family Fungal_trans_2 PF11951.8 KFX98586.1 - 2.1e-17 63.0 0.0 2.9e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.22 KFX98587.1 - 1.1e-37 129.3 0.0 1.4e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family STALD PF18185.1 KFX98587.1 - 0.042 13.2 0.0 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family MFS_1 PF07690.16 KFX98588.1 - 1.2e-36 126.4 46.0 9e-36 123.5 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFX98588.1 - 0.00012 21.5 0.5 0.00012 21.5 0.5 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Ac110_PIF PF07280.11 KFX98588.1 - 1.4 8.8 4.7 4.6 7.1 4.7 1.9 1 0 0 1 1 1 0 Per os infectivity factor AC110 Laminin_G_1 PF00054.23 KFX98589.1 - 0.0025 18.0 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFX98589.1 - 0.0051 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Glyco_hydro_43 PF04616.14 KFX98590.1 - 1e-44 153.0 7.1 1.2e-44 152.8 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_GDSL_2 PF13472.6 KFX98591.1 - 1.6e-21 77.5 1.2 3.3e-21 76.5 1.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX98591.1 - 7.2e-11 42.4 0.1 1e-10 42.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chal_sti_synt_C PF02797.15 KFX98592.1 - 8.4e-24 84.3 0.0 1.7e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KFX98592.1 - 1.9e-20 73.3 0.2 3.2e-20 72.5 0.2 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 KFX98592.1 - 4.4e-05 23.6 0.0 0.00025 21.1 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.12 KFX98592.1 - 0.00016 21.1 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein DUF4345 PF14248.6 KFX98593.1 - 0.00021 21.2 2.2 0.00025 20.9 1.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4345) YndJ PF14158.6 KFX98593.1 - 0.0032 16.8 4.2 0.0042 16.5 4.2 1.1 1 0 0 1 1 1 1 YndJ-like protein BUD22 PF09073.10 KFX98594.1 - 2.4e-96 323.7 34.0 5e-96 322.7 34.0 1.5 1 1 0 1 1 1 1 BUD22 Hva1_TUDOR PF11160.8 KFX98595.1 - 5.9e-17 61.6 0.1 2.4e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Sugar_tr PF00083.24 KFX98596.1 - 3.3e-123 411.9 24.8 3.8e-123 411.7 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98596.1 - 4.8e-26 91.5 54.3 6.6e-24 84.5 29.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX98596.1 - 0.029 12.8 9.1 0.019 13.4 3.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PDR_assoc PF08370.11 KFX98596.1 - 0.067 12.9 0.7 1.6 8.6 0.1 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated TMEM132D_C PF15706.5 KFX98596.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Phage_holin_3_2 PF04550.12 KFX98596.1 - 0.23 12.1 4.7 0.74 10.4 4.7 1.9 1 0 0 1 1 1 0 Phage holin family 2 Tower PF09121.10 KFX98603.1 - 0.12 12.6 7.0 11 6.3 0.6 3.8 3 0 0 3 3 3 0 Tower PI3_PI4_kinase PF00454.27 KFX98607.1 - 5e-43 147.7 0.0 7.9e-40 137.2 0.0 3.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFX98607.1 - 1.5e-23 83.2 0.1 1.1e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 KFX98608.1 - 8.6e-29 100.4 0.2 1.6e-28 99.5 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit C2 PF00168.30 KFX98609.1 - 1.8e-09 37.8 0.0 3.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain DMAP1 PF05499.12 KFX98609.1 - 0.0093 15.9 0.3 0.0093 15.9 0.3 2.2 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) 4HBT_3 PF13622.6 KFX98611.1 - 4.8e-50 171.1 0.0 5.8e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KFX98611.1 - 0.12 12.8 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Thioesterase superfamily HMA PF00403.26 KFX98620.1 - 1.6e-06 28.4 0.0 2.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain CN_hydrolase PF00795.22 KFX98623.1 - 2.4e-60 204.1 0.0 2.7e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mif2_N PF15624.6 KFX98627.1 - 1.8e-36 125.8 4.2 1.8e-36 125.8 4.2 3.4 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KFX98627.1 - 4.1e-31 107.0 0.0 6.6e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KFX98627.1 - 2.4e-10 39.9 0.0 4.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX98627.1 - 0.0013 18.3 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KFX98627.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Fructosamin_kin PF03881.14 KFX98628.1 - 4.6e-70 236.1 0.0 5.3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFX98628.1 - 4.8e-05 23.4 0.0 8.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFX98628.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFX98628.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase TAF4 PF05236.14 KFX98629.1 - 2e-29 103.3 0.5 1.3e-25 90.8 0.1 2.3 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KFX98630.1 - 1.6e-88 295.9 0.0 2.3e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFX98630.1 - 2.1e-29 102.0 0.0 4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KFX98630.1 - 2.1e-19 70.3 0.4 2.1e-19 70.3 0.4 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFX98630.1 - 3.5e-18 65.7 0.1 5.8e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFX98630.1 - 6.8e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFX98630.1 - 7.8e-06 25.5 0.7 1.8e-05 24.3 0.3 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFX98630.1 - 0.00016 21.6 0.1 0.00037 20.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFX98630.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family CN_hydrolase PF00795.22 KFX98631.1 - 4.9e-55 186.7 0.0 5.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mito_carr PF00153.27 KFX98632.1 - 1.9e-51 172.0 2.4 3.8e-18 65.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TrbI_Ftype PF09677.10 KFX98633.1 - 0.62 10.4 2.6 1.7 9.0 2.6 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Prefoldin_2 PF01920.20 KFX98634.1 - 3.8e-20 71.8 3.7 4.8e-20 71.5 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit FlxA PF14282.6 KFX98634.1 - 0.0047 16.9 8.0 0.23 11.4 5.8 2.2 2 0 0 2 2 2 1 FlxA-like protein Rootletin PF15035.6 KFX98634.1 - 0.02 14.9 2.7 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KFX98634.1 - 0.037 14.1 4.3 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KFX98634.1 - 0.055 13.6 2.9 1.6 8.9 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like MetOD2 PF18548.1 KFX98634.1 - 0.056 13.5 6.1 0.085 13.0 0.2 2.7 2 1 1 3 3 3 0 Metanogen output domain 2 GM_CSF PF01109.17 KFX98634.1 - 0.12 12.6 1.0 0.28 11.3 0.4 1.7 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor CC2-LZ PF16516.5 KFX98634.1 - 0.13 12.7 4.5 3.2 8.2 1.3 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BLOC1_2 PF10046.9 KFX98634.1 - 0.13 12.6 5.4 0.48 10.8 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rho_Binding PF08912.11 KFX98634.1 - 0.17 12.8 3.7 0.97 10.3 0.1 2.2 2 0 0 2 2 2 0 Rho Binding Tektin PF03148.14 KFX98634.1 - 0.32 9.7 7.7 2.5 6.8 7.7 1.9 1 1 0 1 1 1 0 Tektin family Fungal_TACC PF12709.7 KFX98634.1 - 0.54 10.7 5.1 1.6 9.3 0.1 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KFX98634.1 - 0.55 10.9 7.1 49 4.6 7.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Fib_alpha PF08702.10 KFX98634.1 - 0.6 10.3 9.0 0.54 10.4 0.1 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 KFX98634.1 - 2.9 7.7 6.2 1.8 8.4 3.8 1.7 1 1 1 2 2 2 0 USP8 interacting TMF_TATA_bd PF12325.8 KFX98635.1 - 9.6e-40 135.4 10.1 9.6e-40 135.4 10.1 6.0 3 2 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFX98635.1 - 5.4e-18 64.8 13.3 5.4e-18 64.8 13.3 7.5 5 3 3 8 8 8 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 KFX98635.1 - 0.0028 17.8 15.7 0.0028 17.8 15.7 4.9 3 1 2 5 5 5 1 Tropomyosin like ATG16 PF08614.11 KFX98635.1 - 0.012 15.8 3.7 0.012 15.8 3.7 5.8 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Filament PF00038.21 KFX98635.1 - 0.08 12.5 75.9 0.059 13.0 27.5 4.1 2 1 2 4 4 4 0 Intermediate filament protein Holin_BhlA PF10960.8 KFX98635.1 - 0.087 12.8 8.8 0.22 11.5 0.4 3.4 2 0 0 2 2 2 0 BhlA holin family WD40_alt PF14077.6 KFX98635.1 - 3.4 7.6 16.1 0.092 12.6 0.8 4.9 5 0 0 5 5 5 0 Alternative WD40 repeat motif Ank_4 PF13637.6 KFX98636.1 - 4.8e-39 132.2 1.8 1.9e-08 34.7 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX98636.1 - 4.3e-36 123.4 0.3 1e-11 45.3 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX98636.1 - 6.8e-36 121.9 0.8 1.1e-07 31.9 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX98636.1 - 1.5e-28 95.7 0.0 0.00057 20.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFX98636.1 - 1.7e-26 91.4 1.3 6.5e-06 26.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.32 KFX98637.1 - 6.9e-44 147.0 14.2 1.6e-09 38.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98637.1 - 1.9e-05 24.8 0.4 10 6.5 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX98637.1 - 0.018 13.7 1.5 10 4.7 0.0 4.1 2 1 3 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFX98637.1 - 0.2 11.0 0.0 0.56 9.5 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain AAA PF00004.29 KFX98638.1 - 9.4e-16 58.4 0.0 2.6e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KFX98638.1 - 6.8e-11 42.2 0.2 2e-10 40.7 0.0 1.8 2 0 0 2 2 1 1 AAA lid domain AAA_22 PF13401.6 KFX98638.1 - 1.2e-10 41.8 0.0 1.8e-09 38.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFX98638.1 - 1.7e-10 41.5 0.0 2e-09 38.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KFX98638.1 - 3.7e-08 33.3 0.0 1.2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.6 KFX98638.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX98638.1 - 0.0061 16.4 1.3 0.014 15.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KFX98638.1 - 0.0092 15.9 0.0 0.44 10.4 0.0 2.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFX98638.1 - 0.015 15.9 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFX98638.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KFX98638.1 - 0.031 14.7 0.1 0.5 10.8 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 KFX98638.1 - 0.034 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KFX98638.1 - 0.035 12.9 0.0 0.08 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX98638.1 - 0.037 14.0 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 KFX98638.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Microtub_bd PF16796.5 KFX98638.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding ARL2_Bind_BART PF11527.8 KFX98639.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Prefoldin PF02996.17 KFX98640.1 - 4e-26 91.3 0.1 5.5e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFX98640.1 - 0.0029 17.5 2.6 0.42 10.6 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit Med30 PF11315.8 KFX98640.1 - 0.0093 16.2 0.0 0.86 9.8 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 30 GIT_CC PF16559.5 KFX98640.1 - 0.011 15.6 0.4 0.023 14.6 0.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor UvsW PF11637.8 KFX98640.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW DUF1664 PF07889.12 KFX98640.1 - 0.018 15.1 1.2 0.54 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFX98640.1 - 0.054 13.5 0.8 0.32 11.0 0.1 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4854 PF16146.5 KFX98640.1 - 0.085 13.2 0.4 0.45 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Sec2p PF06428.11 KFX98640.1 - 0.093 12.7 2.5 5 7.2 0.3 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 KFX98640.1 - 0.13 12.4 1.0 14 5.9 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family tRNA-synt_2b PF00587.25 KFX98641.1 - 1.3e-29 103.4 0.0 1.3e-25 90.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFX98641.1 - 2.5e-10 40.4 0.0 4.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 KFX98642.1 - 1.2e-54 184.9 0.1 4.3e-54 183.1 0.1 2.0 1 0 0 1 1 1 1 CBF/Mak21 family 4HBT PF03061.22 KFX98643.1 - 1.6e-10 41.2 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CASP_C PF08172.12 KFX98650.1 - 2.9e-90 302.0 0.2 2.9e-90 302.0 0.2 3.9 4 0 0 4 4 4 2 CASP C terminal Cep57_MT_bd PF06657.13 KFX98650.1 - 0.00041 20.7 23.2 0.0062 17.0 1.5 4.8 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Med21 PF11221.8 KFX98650.1 - 0.0098 16.2 4.2 0.0098 16.2 4.2 4.6 4 1 0 5 5 5 1 Subunit 21 of Mediator complex UPF0184 PF03670.13 KFX98650.1 - 0.066 13.6 9.1 0.94 9.9 0.5 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) ZapB PF06005.12 KFX98650.1 - 0.15 12.6 0.2 0.097 13.1 6.2 6.6 5 1 1 6 6 6 0 Cell division protein ZapB LPP PF04728.13 KFX98650.1 - 0.23 11.9 14.3 2.3 8.6 0.4 5.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Mit_KHE1 PF10173.9 KFX98650.1 - 0.43 10.6 3.9 1.2 9.2 3.9 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related LemA PF04011.12 KFX98650.1 - 1.5 8.6 8.7 0.14 12.0 1.0 3.0 2 1 0 3 3 3 0 LemA family OmpH PF03938.14 KFX98650.1 - 2.9 8.2 31.6 0.73 10.2 8.6 4.9 5 0 0 5 5 5 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 KFX98650.1 - 3.7 8.0 40.7 0.84 10.1 0.3 5.3 5 1 0 5 5 5 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KFX98650.1 - 8.7 6.4 27.8 3.2 7.8 0.3 5.6 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KFX98650.1 - 8.8 6.7 43.2 2.5 8.5 16.0 4.3 3 1 1 4 4 4 0 Fez1 Tri3 PF07428.11 KFX98651.1 - 1.3e-17 63.8 0.0 3.7e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 2_5_RNA_ligase2 PF13563.6 KFX98651.1 - 0.044 13.7 0.1 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily AMP-binding PF00501.28 KFX98652.1 - 2.5e-216 718.2 0.0 2.5e-75 253.7 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFX98652.1 - 2.1e-150 501.4 0.0 3.3e-42 144.7 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KFX98652.1 - 8.4e-34 115.7 0.2 2.8e-12 46.8 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX98652.1 - 6.7e-07 30.2 0.1 0.49 11.4 0.0 4.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain PS_Dcarbxylase PF02666.15 KFX98653.1 - 3.1e-18 66.0 0.0 3.5e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MFS_1 PF07690.16 KFX98654.1 - 3.8e-06 26.1 19.7 3.9e-06 26.0 9.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KFX98655.1 - 4e-26 92.1 0.0 1.4e-25 90.4 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ArabFuran-catal PF09206.11 KFX98656.1 - 4.4e-148 492.8 16.4 6.3e-148 492.2 16.4 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KFX98656.1 - 2.3e-54 183.2 1.2 4.2e-54 182.3 1.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain NDK PF00334.19 KFX98690.1 - 1.4e-52 177.3 0.0 1.8e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 KFX98691.1 - 3.5e-143 478.0 4.8 5.2e-143 477.4 4.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFX98691.1 - 1.1e-23 83.3 2.2 1.1e-23 83.3 0.5 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFX98691.1 - 1.9e-06 28.0 0.2 9.7e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Ank_2 PF12796.7 KFX98692.1 - 6.9e-33 113.1 6.0 7.1e-12 45.7 0.1 8.3 7 1 0 7 7 7 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX98692.1 - 6e-24 81.5 5.3 0.0088 16.5 0.1 10.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KFX98692.1 - 1.3e-23 82.7 3.3 0.0022 18.2 0.0 8.8 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX98692.1 - 1.9e-21 75.5 12.7 0.0045 17.4 0.1 9.4 9 1 1 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 KFX98692.1 - 2.3e-21 75.9 6.6 0.00049 20.6 0.2 8.8 7 1 1 8 8 8 5 Ankyrin repeats (many copies) DUF4407 PF14362.6 KFX98695.1 - 0.04 13.3 0.3 0.051 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KinB_sensor PF16767.5 KFX98695.1 - 0.11 12.9 0.4 1.3 9.5 0.1 2.3 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB DinB_2 PF12867.7 KFX98695.1 - 0.28 11.7 2.5 8.3 6.9 2.4 2.3 1 1 0 1 1 1 0 DinB superfamily Baculo_PEP_C PF04513.12 KFX98695.1 - 0.32 11.0 1.3 3 7.9 0.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMA PF00403.26 KFX98696.1 - 5.9e-15 55.5 0.7 6.9e-15 55.2 0.1 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Tcf25 PF04910.14 KFX98697.1 - 7.1e-64 216.1 0.1 1.2e-63 215.4 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Latrophilin PF02354.16 KFX98697.1 - 6.9 5.6 10.6 1.7 7.6 6.9 1.7 1 1 1 2 2 2 0 Latrophilin Cytoplasmic C-terminal region PP2C PF00481.21 KFX98698.1 - 3.4e-39 135.1 0.0 5.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFX98698.1 - 0.012 15.6 0.0 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) adh_short PF00106.25 KFX98700.1 - 4.9e-37 127.3 0.0 6.6e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98700.1 - 3.9e-22 79.0 0.0 5.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX98700.1 - 0.00016 21.6 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX98700.1 - 0.025 13.7 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3886 PF13025.6 KFX98701.1 - 1.2 9.4 9.2 0.12 12.5 2.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) ketoacyl-synt PF00109.26 KFX98702.1 - 4.3e-74 249.3 0.1 9.4e-74 248.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KFX98702.1 - 3.4e-35 119.8 0.0 1.1e-34 118.2 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KFX98702.1 - 4e-29 101.0 0.1 9.4e-29 99.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFX98702.1 - 1.2e-26 93.4 0.0 2.3e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KFX98702.1 - 9.8e-26 91.0 0.0 2.2e-24 86.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KFX98702.1 - 2.2e-17 63.6 4.1 2e-15 57.2 0.5 2.9 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KFX98702.1 - 2.5e-14 53.8 0.0 9.1e-14 52.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98702.1 - 4.4e-11 43.4 0.0 2.2e-10 41.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX98702.1 - 7.4e-11 42.1 0.0 2.3e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFX98702.1 - 2.4e-10 40.6 1.0 7.8e-10 39.0 1.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KFX98702.1 - 2.9e-10 40.6 0.0 8.9e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KFX98702.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 KFX98702.1 - 7.4e-09 35.6 0.0 1.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KFX98702.1 - 2.8e-07 30.2 0.2 3.5e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFX98702.1 - 9.6e-06 26.0 0.0 2.8e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension NodS PF05401.11 KFX98702.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 KFX98702.1 - 0.00014 21.3 0.0 0.0004 19.8 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFX98702.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase PS-DH PF14765.6 KFX98702.1 - 0.00022 20.6 0.0 0.00045 19.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFX98702.1 - 0.00054 19.9 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX98702.1 - 0.0017 17.6 0.0 0.01 15.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX98702.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFX98702.1 - 0.013 14.7 0.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RmlD substrate binding domain RrnaAD PF00398.20 KFX98702.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FSH1 PF03959.13 KFX98703.1 - 4.9e-27 95.0 0.0 6.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFX98703.1 - 0.0092 16.6 1.3 0.012 16.3 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFX98703.1 - 0.01 15.7 0.6 0.042 13.6 0.1 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Transferase PF02458.15 KFX98704.1 - 1.4e-27 96.4 0.0 2.4e-27 95.7 0.0 1.3 2 0 0 2 2 2 1 Transferase family FAD_binding_3 PF01494.19 KFX98705.1 - 1.4e-18 67.3 6.2 4.7e-13 49.1 1.7 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX98705.1 - 7.9e-06 25.7 0.8 2.4e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX98705.1 - 0.00053 20.2 0.6 0.0016 18.6 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX98705.1 - 0.0011 18.3 0.2 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX98705.1 - 0.0063 15.7 1.6 0.033 13.3 0.5 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 KFX98705.1 - 0.033 14.7 0.5 0.071 13.7 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX98706.1 - 3e-12 46.6 0.4 7.9e-12 45.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFX98706.1 - 3.4e-09 36.6 0.1 6.4e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX98706.1 - 1.9e-05 24.1 0.1 3.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX98706.1 - 2.8e-05 23.4 1.2 4.3e-05 22.8 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX98706.1 - 3.4e-05 22.7 0.7 5.3e-05 22.1 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFX98706.1 - 4.7e-05 23.9 0.1 9.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX98706.1 - 0.00015 21.5 0.3 0.00065 19.4 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFX98706.1 - 0.00041 19.8 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KFX98706.1 - 0.0061 15.7 0.1 0.0086 15.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFX98706.1 - 0.0064 15.8 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX98706.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KFX98706.1 - 0.022 14.4 1.0 0.045 13.4 0.6 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 KFX98706.1 - 0.024 13.9 0.1 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.26 KFX98707.1 - 1.9e-08 34.3 0.1 4.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98707.1 - 5.2e-08 32.7 0.1 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFX98707.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_49 PF03718.13 KFX98707.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 p450 PF00067.22 KFX98708.1 - 3.9e-52 177.6 0.0 5.1e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 KFX98709.1 - 1.4e-16 61.4 0.7 1.6e-16 61.2 0.7 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFX98709.1 - 9.5e-05 22.8 0.1 0.0002 21.8 0.1 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase XdhC_C PF13478.6 KFX98709.1 - 0.045 14.2 0.0 0.045 14.2 0.0 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain SinI PF08671.10 KFX98709.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Anti-repressor SinI Zn_clus PF00172.18 KFX98711.1 - 3e-07 30.5 9.4 3e-07 30.5 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KFX98711.1 - 7.8 6.9 12.8 3.5 8.0 9.3 2.3 2 0 0 2 2 2 0 Opy2 protein ketoacyl-synt PF00109.26 KFX98712.1 - 1.5e-69 234.4 0.0 4.9e-69 232.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFX98712.1 - 5.5e-60 202.3 1.1 1.5e-59 201.0 0.1 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KFX98712.1 - 6.6e-54 183.2 0.0 1.2e-53 182.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFX98712.1 - 2.9e-51 174.9 0.0 6.2e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX98712.1 - 1.2e-37 128.5 0.6 4.1e-37 126.8 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFX98712.1 - 1.4e-11 44.8 0.0 3.5e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFX98712.1 - 3e-08 33.4 0.0 7.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98712.1 - 8.9e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KFX98712.1 - 0.00015 22.0 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KFX98712.1 - 0.00046 21.2 0.1 0.0025 18.9 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX98712.1 - 0.00062 19.7 0.0 0.0024 17.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 KFX98712.1 - 0.045 13.6 0.9 0.5 10.2 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KFX98712.1 - 0.051 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Epimerase PF01370.21 KFX98713.1 - 2.4e-14 53.4 0.0 3.4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX98713.1 - 5e-13 48.7 0.0 1e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX98713.1 - 1.8e-09 37.1 0.2 5.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KFX98713.1 - 4.9e-09 36.0 0.0 9e-09 35.2 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX98713.1 - 5e-09 36.3 0.1 7.8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX98713.1 - 1.9e-06 27.6 0.0 3.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KFX98713.1 - 0.00016 21.0 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX98713.1 - 0.0045 16.1 0.2 0.057 12.5 0.2 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFX98713.1 - 0.065 12.7 0.0 0.77 9.2 0.0 2.5 2 1 1 3 3 3 0 short chain dehydrogenase F420_oxidored PF03807.17 KFX98714.1 - 7.9e-09 36.0 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KFX98714.1 - 1.9e-05 24.5 0.1 0.0003 20.7 0.1 2.1 1 1 0 1 1 1 1 Rossmann-like domain ADH_zinc_N PF00107.26 KFX98717.1 - 2e-14 53.7 0.1 3.8e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98717.1 - 9.2e-06 25.5 0.8 5.3e-05 23.1 0.0 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX98717.1 - 0.001 20.1 0.0 0.0043 18.1 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX98717.1 - 0.011 15.7 0.0 0.051 13.5 0.0 2.2 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase CAP59_mtransfer PF11735.8 KFX98718.1 - 2.4e-67 227.1 0.0 3.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Amidohydro_1 PF01979.20 KFX98719.1 - 2.7e-58 197.9 0.0 4.4e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family PPR_2 PF13041.6 KFX98719.1 - 4.8e-18 65.1 4.7 7.1e-06 26.1 0.1 7.5 6 1 1 7 7 7 3 PPR repeat family PPR_long PF17177.4 KFX98719.1 - 8.6e-14 51.4 0.5 1e-05 25.0 0.0 3.9 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP Amidohydro_3 PF07969.11 KFX98719.1 - 6.5e-13 49.0 0.1 1.7e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family PPR PF01535.20 KFX98719.1 - 1.6e-11 43.6 9.6 0.63 10.4 0.0 9.6 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 KFX98719.1 - 4.2e-11 42.8 3.3 0.0027 17.7 0.0 6.2 5 1 2 7 7 7 3 Pentatricopeptide repeat domain Zn_clus PF00172.18 KFX98719.1 - 1.9e-07 31.1 9.3 3.2e-07 30.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_1 PF12854.7 KFX98719.1 - 0.00018 21.2 0.0 0.47 10.2 0.0 4.2 4 0 0 4 4 4 1 PPR repeat TPR_1 PF00515.28 KFX98719.1 - 2.2 8.3 6.1 36 4.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP68 PF16969.5 KFX98720.1 - 2.4e-191 637.5 1.4 2.8e-191 637.4 1.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PMEI PF04043.15 KFX98720.1 - 0.042 14.2 5.5 0.054 13.8 1.7 2.5 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DIE2_ALG10 PF04922.12 KFX98721.1 - 9.8e-60 202.9 0.0 1.2e-59 202.6 0.0 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family GalP_UDP_transf PF01087.22 KFX98722.1 - 7.9e-72 241.5 0.1 4.1e-70 236.0 0.1 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFX98722.1 - 7.1e-59 198.3 0.1 1.4e-58 197.4 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KFX98722.1 - 0.0025 18.5 0.0 0.063 14.0 0.0 2.3 2 0 0 2 2 2 1 HIT domain Filament PF00038.21 KFX98722.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF4921 PF16268.5 KFX98722.1 - 0.16 10.8 0.5 0.68 8.7 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4921) Sld5 PF05916.11 KFX98724.1 - 3e-10 40.5 0.2 5.4e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Glyco_transf_90 PF05686.12 KFX98724.1 - 1.4e-06 27.5 0.0 5.3e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 S-methyl_trans PF02574.16 KFX98725.1 - 9.6e-35 120.7 0.0 1.1e-34 120.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peripla_BP_4 PF13407.6 KFX98725.1 - 0.003 17.2 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peptidase_M24 PF00557.24 KFX98726.1 - 2.3e-33 115.7 0.3 3.4e-33 115.1 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KFX98726.1 - 0.019 15.0 0.6 0.019 15.0 0.6 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 GST_C PF00043.25 KFX98727.1 - 9e-09 35.4 0.0 2.1e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX98727.1 - 2.5e-07 30.8 0.1 7.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX98727.1 - 0.027 14.8 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX98727.1 - 0.043 13.9 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 KFX98728.1 - 9.9e-50 169.4 35.2 9.9e-50 169.4 35.2 3.2 4 0 0 4 4 4 1 Major Facilitator Superfamily Ferric_reduct PF01794.19 KFX98728.1 - 1.4e-18 67.2 12.3 1.4e-18 67.2 12.3 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Sugar_tr PF00083.24 KFX98728.1 - 4e-14 52.3 17.2 4e-14 52.3 17.2 2.9 4 0 0 4 4 4 1 Sugar (and other) transporter FAD_binding_8 PF08022.12 KFX98728.1 - 1.4e-10 41.3 0.0 4.1e-05 23.6 0.0 2.6 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.12 KFX98728.1 - 0.0008 19.6 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Octopine_DH PF02317.17 KFX98729.1 - 8.2e-39 133.1 0.0 1.3e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KFX98729.1 - 1.5e-07 31.6 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KFX98729.1 - 2.5e-05 24.8 0.0 5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KFX98729.1 - 0.0017 17.7 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX98729.1 - 0.0029 16.8 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFX98729.1 - 0.0051 17.0 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFX98729.1 - 0.0053 16.1 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX98729.1 - 0.0073 15.0 0.0 0.015 14.0 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 KFX98729.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFX98729.1 - 0.023 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX98729.1 - 0.061 12.4 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFX98729.1 - 0.11 11.9 0.0 1.1 8.6 0.0 2.2 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KFX98729.1 - 0.13 12.1 0.2 0.79 9.6 0.2 2.1 1 1 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 KFX98729.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.12 KFX98730.1 - 2.4e-23 82.6 0.0 4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98730.1 - 3.5e-22 78.9 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98730.1 - 5.6e-22 78.2 0.0 7.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX98730.1 - 3e-16 59.5 0.0 1.2e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX98730.1 - 5.2e-14 52.8 0.0 8.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX98730.1 - 2.8e-13 50.0 0.0 5e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX98730.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFX98730.1 - 9.5e-08 32.0 0.0 2.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KFX98730.1 - 2.1e-06 27.5 0.0 5.4e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KFX98730.1 - 2.6e-06 26.9 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KFX98730.1 - 8.3e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KFX98730.1 - 0.00015 22.7 0.0 0.00033 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 KFX98730.1 - 0.00053 19.2 0.0 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_29 PF03141.16 KFX98730.1 - 0.0019 16.9 0.0 0.0025 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KFX98730.1 - 0.0055 16.2 0.0 0.06 12.8 0.0 2.5 1 1 1 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KFX98730.1 - 0.0068 15.8 0.2 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 KFX98730.1 - 0.0089 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit ADH_zinc_N PF00107.26 KFX98730.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 KFX98730.1 - 0.022 14.9 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KFX98730.1 - 0.033 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KFX98730.1 - 0.039 13.9 0.0 0.08 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 KFX98730.1 - 0.063 12.8 0.0 1.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 KFX98730.1 - 0.079 12.8 0.1 0.31 10.8 0.1 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 KFX98730.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.22 KFX98731.1 - 3.5e-77 260.1 0.0 4.3e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 fn3_6 PF17766.1 KFX98731.1 - 0.052 13.7 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type-III domain TAXi_C PF14541.6 KFX98731.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Cupin_1 PF00190.22 KFX98733.1 - 1.8e-38 131.5 0.0 5e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KFX98733.1 - 4e-23 80.9 1.1 1.6e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFX98733.1 - 1.8e-07 30.7 0.1 0.022 14.4 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFX98733.1 - 1.8e-05 24.7 0.3 0.049 13.5 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KFX98733.1 - 5.7e-05 22.9 0.1 0.69 9.6 0.0 2.9 2 1 1 3 3 3 2 Cupin 3-HAO PF06052.12 KFX98733.1 - 0.0024 17.5 0.0 1.5 8.4 0.0 2.6 3 0 0 3 3 3 2 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KFX98733.1 - 0.017 15.1 0.2 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 ChrR Cupin-like domain SBP56 PF05694.11 KFX98734.1 - 1.9e-07 30.3 0.0 9e-06 24.8 0.0 2.8 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFX98734.1 - 0.027 13.7 0.0 4 6.6 0.1 2.7 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KFX98734.1 - 0.075 12.6 0.0 4 6.9 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KFX98734.1 - 0.09 12.9 0.2 6.9 6.9 0.0 2.9 3 0 0 3 3 3 0 NHL repeat MR_MLE_C PF13378.6 KFX98735.1 - 1.2e-59 201.6 0.2 1.7e-59 201.1 0.2 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFX98735.1 - 7.7e-20 71.3 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Esterase_phd PF10503.9 KFX98736.1 - 1.4e-21 77.0 1.0 1.7e-21 76.7 1.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX98736.1 - 2.1e-12 47.0 0.5 3.9e-12 46.1 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFX98736.1 - 4.8e-05 23.3 0.3 0.028 14.2 0.2 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 KFX98736.1 - 0.00069 19.3 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFX98736.1 - 0.0026 18.4 1.4 0.0059 17.2 1.4 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFX98736.1 - 0.0028 17.5 0.2 0.0037 17.1 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFX98736.1 - 0.0032 17.1 0.6 0.0095 15.6 0.6 1.8 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KFX98736.1 - 0.0069 15.7 0.4 0.53 9.5 0.1 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KFX98736.1 - 0.064 12.4 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 KFX98736.1 - 0.12 11.9 2.3 0.73 9.4 0.9 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KFX98736.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RNase_H PF00075.24 KFX98737.1 - 4.6e-27 95.0 0.0 7.3e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFX98737.1 - 0.00028 20.7 0.0 0.077 12.8 0.0 2.8 2 1 0 2 2 2 2 Reverse transcriptase-like Glyco_transf_8 PF01501.20 KFX98738.1 - 1.5e-05 24.7 0.4 3.5e-05 23.5 0.2 1.7 2 1 0 2 2 2 1 Glycosyl transferase family 8 Melibiase_2 PF16499.5 KFX98739.1 - 6.2e-65 219.2 0.5 9.3e-65 218.6 0.5 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 KFX98739.1 - 2.2e-18 66.7 0.4 3.5e-18 66.1 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 KFX98739.1 - 3.5e-15 55.8 0.8 6.7e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX98739.1 - 7.2e-06 25.2 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Melibiase RicinB_lectin_2 PF14200.6 KFX98739.1 - 0.00061 20.5 3.1 0.005 17.5 0.5 3.4 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KFX98739.1 - 0.02 14.5 1.9 3.4 7.2 0.2 2.8 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Aldo_ket_red PF00248.21 KFX98746.1 - 3.8e-40 137.9 0.0 5e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KFX98747.1 - 2.8e-33 113.4 24.9 1.5e-07 31.6 0.4 6.7 2 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX98747.1 - 2.4e-21 75.2 26.6 1.9e-05 24.3 3.4 5.6 3 2 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KFX98747.1 - 3.7e-16 59.1 24.5 4.2e-07 29.6 2.1 3.5 1 1 3 4 4 4 4 Leucine-rich repeat KDZ PF18758.1 KFX98747.1 - 0.027 14.1 0.1 5.5 6.5 0.0 2.3 1 1 1 2 2 2 0 Kyakuja-Dileera-Zisupton transposase LRR_6 PF13516.6 KFX98747.1 - 0.1 12.7 0.5 0.1 12.7 0.5 7.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 KFX98747.1 - 0.12 13.1 18.0 15 6.6 0.1 7.7 9 1 0 9 9 9 0 Leucine Rich Repeat BTB PF00651.31 KFX98748.1 - 4.6e-08 33.3 0.0 1.7e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KFX98748.1 - 0.051 13.8 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PCI PF01399.27 KFX98749.1 - 5.4e-10 39.7 0.0 2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.6 KFX98749.1 - 0.12 12.9 0.0 12 6.5 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1376 PF07120.11 KFX98749.1 - 0.14 12.5 0.0 0.58 10.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) OTCace_N PF02729.21 KFX98749.1 - 0.2 11.7 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ribosomal_L18A PF01775.17 KFX98750.1 - 2.2e-54 182.7 0.6 2.9e-54 182.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A SAD_SRA PF02182.17 KFX98751.1 - 1.5e-28 99.5 0.1 2.3e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain AMP-binding PF00501.28 KFX98753.1 - 2.2e-75 253.9 0.0 6.1e-75 252.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KFX98753.1 - 4.8e-74 249.1 0.0 8.3e-74 248.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KFX98753.1 - 1.6e-67 228.2 0.0 3.9e-67 226.9 0.0 1.7 2 0 0 2 2 2 1 Condensation domain PS-DH PF14765.6 KFX98753.1 - 2.5e-54 184.5 0.0 4.4e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFX98753.1 - 3.1e-54 183.6 0.4 1.4e-52 178.2 0.1 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KFX98753.1 - 1.2e-46 159.7 0.0 2.1e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain MFS_1 PF07690.16 KFX98753.1 - 2.7e-41 141.7 48.3 2.7e-41 141.7 48.3 1.8 2 0 0 2 2 1 1 Major Facilitator Superfamily NAD_binding_4 PF07993.12 KFX98753.1 - 6.7e-40 136.9 0.0 3.2e-39 134.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KFX98753.1 - 5.9e-30 103.7 0.0 2.2e-29 101.8 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFX98753.1 - 4.4e-21 75.5 0.0 1.7e-20 73.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KFX98753.1 - 8.6e-21 74.5 0.0 3.1e-16 59.6 0.0 3.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX98753.1 - 1.8e-17 63.4 0.9 1.1e-10 41.7 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFX98753.1 - 1e-16 61.4 0.1 5.6e-16 59.0 0.0 2.4 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFX98753.1 - 4.2e-16 59.4 0.0 1.5e-15 57.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX98753.1 - 3.5e-15 56.4 0.0 1.1e-14 54.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98753.1 - 4.4e-15 55.8 0.1 1.7e-14 53.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX98753.1 - 4.5e-15 55.9 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFX98753.1 - 4.2e-13 49.2 1.7 1.4e-12 47.5 0.1 2.7 3 0 0 3 3 3 1 short chain dehydrogenase Sugar_tr PF00083.24 KFX98753.1 - 9.7e-13 47.8 10.8 2.7e-12 46.3 10.8 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter 3Beta_HSD PF01073.19 KFX98753.1 - 4.2e-12 45.6 0.0 5e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KFX98753.1 - 7.9e-10 38.5 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GDP_Man_Dehyd PF16363.5 KFX98753.1 - 5.9e-06 25.9 0.0 0.021 14.2 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 KFX98753.1 - 4e-05 23.4 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KFX98753.1 - 4.6e-05 22.9 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_3 PF05977.13 KFX98753.1 - 0.0065 14.9 9.7 0.011 14.2 9.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector NAD_binding_10 PF13460.6 KFX98753.1 - 0.0079 16.1 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Methyltransf_33 PF10017.9 KFX98753.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_8 PF05148.15 KFX98753.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Semialdhyde_dh PF01118.24 KFX98753.1 - 0.053 14.0 0.1 1.1 9.7 0.0 3.0 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain RrnaAD PF00398.20 KFX98753.1 - 0.18 10.9 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Zn_clus PF00172.18 KFX98754.1 - 4e-05 23.6 9.1 7.5e-05 22.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KFX98755.1 - 2.7e-62 211.1 0.0 3.4e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NPR1_like_C PF12313.8 KFX98755.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal FMO-like PF00743.19 KFX98756.1 - 2.7e-41 141.6 0.0 4.5e-21 74.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX98756.1 - 3.8e-17 62.5 0.1 2.2e-13 50.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX98756.1 - 7.7e-14 51.6 0.1 8.5e-13 48.2 0.1 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX98756.1 - 2.3e-08 34.5 0.3 0.00035 21.1 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX98756.1 - 3.6e-08 33.4 1.8 0.053 13.1 1.5 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFX98756.1 - 8.9e-08 31.8 0.1 0.0013 18.1 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFX98756.1 - 2.2e-07 31.0 1.7 1.3e-05 25.2 1.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX98756.1 - 2.2e-06 27.8 0.0 9.3e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX98756.1 - 2.7e-05 23.5 1.4 0.00012 21.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFX98756.1 - 0.0005 19.4 0.6 0.001 18.3 0.6 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFX98756.1 - 0.0031 16.9 1.4 0.25 10.6 1.1 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFX98756.1 - 0.0049 15.6 1.0 0.0093 14.7 1.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 KFX98756.1 - 0.0051 16.9 0.3 2.2 8.3 0.3 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 KFX98756.1 - 0.012 15.0 0.1 0.089 12.1 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX98756.1 - 0.014 14.7 0.8 0.037 13.3 0.8 1.6 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFX98756.1 - 0.12 11.7 0.1 18 4.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFX98756.1 - 0.18 12.0 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFX98756.1 - 0.22 11.4 0.5 0.46 10.3 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFX98756.1 - 0.29 10.2 1.1 0.58 9.2 1.1 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KFX98756.1 - 0.49 10.0 2.3 18 5.0 0.7 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.13 KFX98757.1 - 1.3e-47 162.4 0.0 1.9e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX98757.1 - 6.7e-05 21.9 0.1 0.00018 20.5 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family PsbU PF06514.11 KFX98757.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.7 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF2808 PF10989.8 KFX98757.1 - 0.19 11.7 0.2 0.3 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) MFS_1 PF07690.16 KFX98758.1 - 2.3e-31 109.0 24.7 7e-25 87.7 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFX98758.1 - 0.0028 17.0 2.9 0.0028 17.0 2.9 2.5 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB VIT1 PF01988.19 KFX98758.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.4 2 1 1 3 3 3 0 VIT family ADH_zinc_N PF00107.26 KFX98760.1 - 2.9e-12 46.7 0.0 5.2e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98760.1 - 0.00039 20.3 0.0 0.017 15.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX98760.1 - 0.00065 20.8 0.0 0.0017 19.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF1100 PF06500.11 KFX98761.1 - 4.3e-10 39.0 0.0 1.3e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KFX98761.1 - 1.3e-07 32.5 1.9 1.2e-06 29.3 0.2 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFX98761.1 - 1.6e-06 27.8 0.1 6.8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KFX98761.1 - 0.00029 20.6 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KFX98761.1 - 0.041 13.1 0.2 0.33 10.2 0.1 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX98761.1 - 0.051 13.2 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KFX98761.1 - 0.078 11.5 0.0 0.26 9.7 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Zn_clus PF00172.18 KFX98762.1 - 1.3e-06 28.4 5.5 2.4e-06 27.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX98763.1 - 2.5e-19 69.5 0.8 1.9e-16 60.1 1.8 3.0 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98763.1 - 1e-10 41.6 0.3 1.6e-09 37.7 0.2 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX98763.1 - 0.00033 20.6 0.3 0.0011 18.9 0.4 1.8 2 0 0 2 2 2 1 KR domain SnoaL_3 PF13474.6 KFX98763.1 - 0.16 12.3 0.0 0.51 10.6 0.0 1.9 1 0 0 1 1 1 0 SnoaL-like domain DUF1656 PF07869.12 KFX98764.1 - 0.16 12.0 1.8 0.35 10.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) 2OG-FeII_Oxy PF03171.20 KFX98765.1 - 0.019 15.5 0.0 0.07 13.6 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 KFX98766.1 - 9.5e-50 169.0 0.1 1.4e-49 168.4 0.1 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KFX98766.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.7 2 0 0 2 2 2 0 Fascin domain DUF3395 PF11875.8 KFX98767.1 - 2.1e-28 99.2 1.2 1.3e-27 96.6 1.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFX98767.1 - 2.6e-14 53.1 0.4 6.9e-14 51.7 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KFX98768.1 - 2.3e-10 40.0 0.0 3.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98768.1 - 1.5e-09 37.8 11.1 2.5e-09 37.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_1 PF00175.21 KFX98769.1 - 2.5e-29 102.1 0.0 4.4e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFX98769.1 - 1.6e-22 79.7 0.0 2.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFX98769.1 - 1.6e-09 38.1 0.0 7.2e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KFX98769.1 - 0.021 15.0 0.0 0.071 13.3 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TEA PF01285.18 KFX98770.1 - 5.5e-22 77.6 0.0 1.4e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Codanin-1_C PF15296.6 KFX98770.1 - 0.078 13.1 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Codanin-1 C-terminus RRM_1 PF00076.22 KFX98771.1 - 8.9e-75 246.5 1.1 1.3e-17 63.3 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX98771.1 - 3.2e-11 42.9 0.0 0.0089 15.9 0.0 5.0 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_5 PF13893.6 KFX98771.1 - 8.2e-07 28.7 0.0 0.026 14.1 0.0 4.1 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX98771.1 - 4.5e-06 26.6 0.2 2.3 8.3 0.0 3.9 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KFX98771.1 - 1.3e-05 25.2 0.7 0.1 12.7 0.0 5.2 7 1 0 7 7 7 1 Limkain b1 RRM_3 PF08777.11 KFX98771.1 - 2.6e-05 24.2 2.2 1.7 8.7 0.0 3.9 3 0 0 3 3 3 3 RNA binding motif RRM_7 PF16367.5 KFX98771.1 - 4.6e-05 23.5 0.0 4.6 7.4 0.0 4.6 5 0 0 5 5 5 2 RNA recognition motif Smg4_UPF3 PF03467.15 KFX98771.1 - 0.018 15.1 0.9 0.17 11.9 0.5 2.9 3 1 0 3 3 3 0 Smg-4/UPF3 family RRM_Rrp7 PF17799.1 KFX98771.1 - 0.068 13.0 0.0 36 4.1 0.0 3.7 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Dynein_light PF01221.18 KFX98772.1 - 1.6e-40 137.3 1.1 1.9e-40 137.1 1.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 KFX98772.1 - 0.043 13.6 0.1 0.071 12.9 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 48 alpha-hel2 PF14456.6 KFX98774.1 - 0.072 12.4 0.0 0.079 12.3 0.0 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 AT_hook PF02178.19 KFX98777.1 - 0.48 10.5 4.0 1 9.4 4.0 1.6 1 0 0 1 1 1 0 AT hook motif TraV PF09676.10 KFX98777.1 - 2.3 9.2 7.7 1.9 9.4 3.0 2.0 1 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Stm1_N PF09598.10 KFX98799.1 - 5.9e-14 52.7 5.5 5.9e-14 52.7 5.5 4.2 3 2 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KFX98799.1 - 9.1e-06 26.5 4.1 9.1e-06 26.5 4.1 2.8 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Ribosomal_L6e PF01159.19 KFX98799.1 - 0.22 12.1 3.1 0.36 11.4 3.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e bZIP_1 PF00170.21 KFX98800.1 - 1.7e-06 28.0 5.6 1.7e-06 28.0 5.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor DUF5595 PF18077.1 KFX98800.1 - 0.14 12.2 0.3 0.68 10.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 KFX98800.1 - 0.18 11.7 2.8 0.41 10.5 2.8 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3890 PF13029.6 KFX98800.1 - 0.22 12.0 0.3 0.4 11.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) bZIP_2 PF07716.15 KFX98800.1 - 1.7 8.8 11.5 0.67 10.1 7.6 2.3 2 1 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 KFX98800.1 - 2.8 7.2 5.8 3.6 6.9 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 KFX98800.1 - 6 6.2 11.7 2.3 7.5 7.3 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Aldo_ket_red PF00248.21 KFX98806.1 - 1.6e-50 172.0 0.0 1.9e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.6 KFX98807.1 - 4.6e-52 176.8 0.0 6.7e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFX98807.1 - 3.5e-05 23.1 0.0 5.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 KFX98807.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 KFX98808.1 - 1e-27 96.9 1.5 1.9e-27 96.0 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98808.1 - 2.1e-06 27.7 6.4 4.5e-06 26.7 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFX98809.1 - 7.2e-113 377.8 26.9 8.9e-113 377.5 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98809.1 - 8.2e-23 80.9 39.3 2.9e-19 69.2 8.5 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX98809.1 - 0.00058 18.4 0.9 0.00058 18.4 0.9 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Popeye PF04831.13 KFX98809.1 - 7.6 6.7 6.3 23 5.1 5.9 2.0 1 1 0 1 1 1 0 Popeye protein conserved region PTS_2-RNA PF01885.16 KFX98824.1 - 2.1e-36 125.6 0.0 2.4e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CDT1 PF08839.11 KFX98824.1 - 0.033 14.5 0.0 0.047 14.0 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like PDCD2_C PF04194.13 KFX98827.1 - 3e-09 37.2 0.4 5.2e-09 36.4 0.4 1.3 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain F-box PF00646.33 KFX98829.1 - 0.016 15.1 0.4 0.047 13.6 0.4 1.8 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.19 KFX98830.1 - 1.1e-10 41.4 0.2 0.0016 17.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Bul1_N PF04425.12 KFX98830.1 - 5.4e-06 25.4 0.3 0.011 14.6 0.5 2.2 1 1 1 2 2 2 2 Bul1 N terminus NAD_binding_8 PF13450.6 KFX98830.1 - 0.00033 20.8 0.1 0.00099 19.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX98830.1 - 0.0012 18.5 0.3 0.0023 17.6 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Bul1_C PF04426.12 KFX98830.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Pyr_redox_2 PF07992.14 KFX98830.1 - 0.0017 17.7 0.0 0.004 16.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX98830.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 2OG-FeII_Oxy_3 PF13640.6 KFX98831.1 - 2.9e-09 37.7 0.0 6.9e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KFX98835.1 - 1.2e-21 76.9 0.0 2.2e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98835.1 - 0.00025 21.1 8.6 0.00054 20.0 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrophobin_2 PF06766.11 KFX98836.1 - 0.055 13.4 5.9 0.12 12.4 5.9 1.6 1 0 0 1 1 1 0 Fungal hydrophobin Glutenin_hmw PF03157.13 KFX98836.1 - 0.22 9.9 38.1 0.32 9.4 38.1 1.2 1 0 0 1 1 1 0 High molecular weight glutenin subunit KilA-N PF04383.13 KFX98837.1 - 0.0042 16.9 0.0 0.023 14.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Hamartin PF04388.12 KFX98837.1 - 1.1 7.8 9.9 1.4 7.5 9.9 1.1 1 0 0 1 1 1 0 Hamartin protein CytochromB561_N PF09786.9 KFX98837.1 - 2.9 6.8 11.0 3.9 6.3 11.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal APH PF01636.23 KFX98840.1 - 6.2e-15 55.8 0.0 1.2e-14 54.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX98840.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase FAD_binding_4 PF01565.23 KFX98841.1 - 1.1e-20 73.7 2.8 2.4e-20 72.7 2.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX98841.1 - 7.9e-06 25.9 0.0 3.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like DUF2020 PF09449.10 KFX98841.1 - 0.84 9.5 2.8 19 5.0 1.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2020) GGACT PF06094.12 KFX98843.1 - 2.3e-13 50.8 0.1 3.1e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Kp4 PF09044.10 KFX98844.1 - 1.5e-64 215.7 13.5 4.3e-36 123.7 5.6 2.0 2 0 0 2 2 2 2 Kp4 MU117 PF15474.6 KFX98844.1 - 0.00048 20.9 10.2 0.086 13.7 3.1 2.5 2 1 0 2 2 2 2 Meiotically up-regulated gene family zf-ribbon_3 PF13248.6 KFX98844.1 - 0.13 11.7 5.8 0.45 10.0 0.6 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Beta-TrCP_D PF12125.8 KFX98844.1 - 0.14 12.1 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP Peptidase_M28 PF04389.17 KFX98845.1 - 5.1e-39 134.0 0.0 9.1e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX98845.1 - 2.2e-10 40.4 0.1 4.6e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFX98845.1 - 0.0046 16.7 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 TFIIE_alpha PF02002.17 KFX98852.1 - 6.2e-18 64.6 0.1 1.1e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-CCHC_2 PF13696.6 KFX98852.1 - 1.8 8.5 3.6 0.92 9.4 0.4 2.1 2 0 0 2 2 2 0 Zinc knuckle PseudoU_synth_1 PF01416.20 KFX98853.1 - 1.3e-10 41.6 0.0 2.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KFX98853.1 - 0.047 13.5 0.6 1.1 9.1 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) Pkinase PF00069.25 KFX98854.1 - 1.9e-61 207.8 0.0 3.5e-59 200.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98854.1 - 3.1e-28 98.8 0.0 2.7e-20 72.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX98854.1 - 2.3e-07 30.4 0.1 7e-07 28.8 0.1 1.8 1 1 1 2 2 2 1 Kinase-like Med22 PF06179.12 KFX98855.1 - 4.4e-19 68.6 0.1 6.5e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF5428 PF17493.2 KFX98855.1 - 0.034 14.6 0.1 0.077 13.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5428) Cofilin_ADF PF00241.20 KFX98856.1 - 8.2e-39 132.2 0.0 1.2e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 KFX98857.1 - 2.2e-65 216.6 3.0 4.9e-21 74.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHFR_1 PF00186.19 KFX98858.1 - 6.3e-30 104.0 0.0 5.1e-23 81.5 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase RibD_C PF01872.17 KFX98858.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 RibD C-terminal domain Rotamase PF00639.21 KFX98859.1 - 3.5e-22 79.2 0.0 5.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFX98859.1 - 9.9e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KFX98859.1 - 8.2e-08 32.2 1.6 1e-07 31.9 0.4 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KFX98859.1 - 0.0012 19.6 0.0 0.0019 19.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 KFX98859.1 - 0.028 14.1 0.7 0.072 12.8 0.7 1.7 1 1 0 1 1 1 0 WW domain RNA_POL_M_15KD PF02150.16 KFX98860.1 - 2.1e-14 53.1 3.0 2.1e-14 53.1 3.0 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KFX98860.1 - 6.5e-12 45.1 0.9 6.5e-12 45.1 0.9 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) GFA PF04828.14 KFX98860.1 - 0.0087 16.4 5.7 0.93 9.9 0.2 2.2 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KFX98860.1 - 0.0095 15.9 5.1 0.3 11.1 2.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KFX98860.1 - 0.035 14.1 4.0 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.19 KFX98860.1 - 0.38 10.8 4.7 1.3 9.1 4.7 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-IS66 PF13005.7 KFX98860.1 - 0.65 10.5 4.2 6.7 7.2 0.3 2.9 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF3716 PF12511.8 KFX98860.1 - 0.75 9.9 8.6 0.53 10.4 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) Nudix_N_2 PF14803.6 KFX98860.1 - 1.8 8.5 7.6 0.66 9.9 2.8 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf_C2H2_10 PF18414.1 KFX98860.1 - 3.5 7.2 5.7 6.3 6.4 1.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-B_box PF00643.24 KFX98860.1 - 3.6 7.8 8.6 36 4.6 0.1 3.1 2 1 1 3 3 3 0 B-box zinc finger Ribosomal_L14 PF00238.19 KFX98861.1 - 1.8e-47 160.4 1.1 2e-47 160.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_Mu_Gp45 PF06890.12 KFX98861.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein SET PF00856.28 KFX98862.1 - 3.4e-09 37.3 0.8 4.4e-07 30.4 0.0 3.0 2 2 1 3 3 3 2 SET domain PPV_E2_N PF00508.17 KFX98862.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal BTB PF00651.31 KFX98863.1 - 5.5e-05 23.4 0.0 0.00027 21.2 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Anillin PF08174.11 KFX98864.1 - 1.1e-15 58.3 0.0 3.6e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFX98864.1 - 3.2e-08 34.0 0.0 1.3e-07 32.0 0.0 2.1 1 0 0 1 1 1 1 PH domain AP-5_subunit_s1 PF15001.6 KFX98864.1 - 1.1 9.2 2.7 0.98 9.4 0.9 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 RNase_P_pop3 PF08228.11 KFX98865.1 - 2.9e-06 27.4 0.0 5.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 GATase PF00117.28 KFX98866.1 - 8.4e-38 130.0 0.0 2.1e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KFX98866.1 - 1.9e-37 127.2 0.0 3.6e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KFX98866.1 - 6e-12 45.2 0.0 3.5e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFX98866.1 - 9.2e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 KFX98866.1 - 0.0028 17.3 0.3 0.0073 15.9 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KFX98866.1 - 0.0064 15.3 0.1 0.017 13.9 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KFX98866.1 - 0.014 14.9 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KFX98866.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 KFX98866.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family DUF3517 PF12030.8 KFX98867.1 - 2.8e-101 338.8 0.5 6.3e-100 334.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 KFX98867.1 - 2.5e-38 132.0 0.4 5e-38 131.1 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX98867.1 - 2.9e-19 69.8 1.0 5.6e-19 68.9 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 KFX98867.1 - 0.16 12.0 2.9 0.15 12.1 0.2 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein Clathrin PF00637.20 KFX98868.1 - 0.02 14.8 0.3 0.085 12.7 0.0 2.3 3 0 0 3 3 3 0 Region in Clathrin and VPS COX7a PF02238.15 KFX98869.1 - 4.4e-23 81.4 3.7 5.2e-23 81.2 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Clathrin_lg_ch PF01086.17 KFX98870.1 - 2.9e-75 253.3 8.1 3.3e-75 253.1 8.1 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.13 KFX98871.1 - 2.5e-18 66.7 0.1 5e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KFX98871.1 - 0.0066 16.5 0.3 0.013 15.5 0.3 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3277 PF11681.8 KFX98871.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) LepA_C PF06421.12 KFX98871.1 - 0.047 13.8 0.7 2.9 8.1 0.1 2.4 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus CREPT PF16566.5 KFX98871.1 - 0.54 10.4 3.8 0.22 11.7 0.8 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CDC37_N PF03234.14 KFX98872.1 - 4.3e-47 160.2 1.6 4.3e-47 160.2 1.6 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KFX98872.1 - 5.9e-42 142.3 0.3 2.9e-41 140.1 0.0 2.3 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KFX98872.1 - 1.3e-29 102.3 2.9 1.3e-29 102.3 2.9 2.8 2 1 0 2 2 2 1 Cdc37 C terminal domain Seryl_tRNA_N PF02403.22 KFX98872.1 - 1.5 9.1 9.0 0.19 12.0 0.7 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LUC7 PF03194.15 KFX98872.1 - 1.7 8.2 11.9 0.015 15.0 1.8 2.4 3 0 0 3 3 3 0 LUC7 N_terminus ABC_membrane PF00664.23 KFX98873.1 - 1.3e-51 175.9 10.3 1.9e-51 175.3 10.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFX98873.1 - 1.7e-32 112.8 0.0 4.1e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Glyco_hydro_16 PF00722.21 KFX98873.1 - 7.1e-08 32.1 0.1 2.4e-07 30.4 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 SMC_N PF02463.19 KFX98873.1 - 0.0015 18.0 0.0 0.0069 15.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX98873.1 - 0.037 13.8 0.4 0.088 12.6 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX98873.1 - 0.082 13.3 0.2 0.38 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFX98873.1 - 0.097 12.9 0.2 0.7 10.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain Nitroreductase PF00881.24 KFX98874.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PsbY PF06298.11 KFX98874.1 - 0.014 15.3 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Cmyb_C PF09316.10 KFX98874.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 C-myb, C-terminal UBA_4 PF14555.6 KFX98876.1 - 2.9e-13 49.4 1.8 3.9e-13 49.0 1.8 1.2 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 KFX98876.1 - 5.8e-05 22.6 0.0 7.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 TAP C-terminal domain TOM13 PF08219.11 KFX98877.1 - 1.1e-36 124.7 0.0 1.4e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF3449 PF11931.8 KFX98878.1 - 2.6e-74 249.0 0.0 2.9e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Kinesin PF00225.23 KFX98882.1 - 6.2e-14 51.7 0.0 8.3e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX98882.1 - 6.1e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Ish1 PF10281.9 KFX98883.1 - 1.4e-88 290.8 29.0 7.4e-15 55.0 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KFX98883.1 - 8.8e-13 47.7 0.9 0.0029 17.3 0.0 6.3 7 0 0 7 7 7 3 HeH/LEM domain SAP PF02037.27 KFX98883.1 - 5.7e-10 38.7 0.0 0.54 10.1 0.0 6.8 6 1 0 6 6 6 2 SAP domain Slx4 PF09494.10 KFX98883.1 - 1e-05 25.4 1.1 12 5.9 0.0 6.5 7 0 0 7 7 7 2 Slx4 endonuclease Endonuc-dimeris PF09124.10 KFX98883.1 - 0.00057 20.0 0.0 2 8.6 0.0 4.2 4 0 0 4 4 4 1 T4 recombination endonuclease VII, dimerisation SAM_2 PF07647.17 KFX98883.1 - 0.0072 16.4 2.4 7 6.8 0.0 4.0 4 0 0 4 4 4 2 SAM domain (Sterile alpha motif) SAP30_Sin3_bdg PF13867.6 KFX98883.1 - 0.013 15.9 0.3 19 5.7 0.0 5.2 7 0 0 7 7 7 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Virulence_fact PF13769.6 KFX98883.1 - 0.19 12.0 1.2 5.7 7.2 0.2 3.2 2 0 0 2 2 2 0 Virulence factor Polyoma_agno PF01736.16 KFX98883.1 - 0.23 11.2 1.0 0.76 9.5 1.0 1.9 1 0 0 1 1 1 0 Polyomavirus agnoprotein DUF4518 PF15008.6 KFX98883.1 - 0.34 10.0 6.0 1.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4518) Apolipoprotein PF01442.18 KFX98883.1 - 0.7 9.7 10.5 0.98 9.3 0.0 4.0 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain CoA_transf_3 PF02515.17 KFX98884.1 - 6.9e-106 354.5 0.0 9.7e-106 354.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.22 KFX98884.1 - 2.4e-51 175.0 0.0 3.7e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFX98893.1 - 5.5e-58 196.8 0.0 7.4e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 KFX98905.1 - 7.6e-12 45.0 9.9 2.9e-06 27.4 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX98905.1 - 4.7e-08 33.1 2.0 4.7e-08 33.1 2.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX98905.1 - 3.3e-05 24.3 16.0 0.0035 18.0 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX98905.1 - 0.00079 19.4 5.4 0.0033 17.4 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX98905.1 - 0.0058 16.9 0.1 0.45 10.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFX98905.1 - 0.016 15.4 2.1 0.037 14.3 2.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KFX98905.1 - 0.04 14.3 0.7 0.53 10.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CENP-Q PF13094.6 KFX98905.1 - 0.11 12.7 0.4 0.17 12.1 0.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Choline_kinase PF01633.20 KFX98927.1 - 2.9e-60 203.5 0.0 8.2e-60 202.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KFX98927.1 - 5.3e-22 77.3 0.1 1.3e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 KFX98927.1 - 7e-07 29.4 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Mem_trans PF03547.18 KFX98928.1 - 1.2e-50 172.1 2.1 3.5e-50 170.5 2.1 1.7 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 KFX98929.1 - 1.4e-52 178.6 0.0 2.4e-49 168.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98929.1 - 1.6e-31 109.5 0.0 3.7e-30 105.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX98929.1 - 0.00031 19.8 0.0 0.00045 19.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX98929.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFX98929.1 - 0.0046 16.1 0.1 0.0075 15.4 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 DNA_methylase PF00145.17 KFX98930.1 - 1.4e-16 60.8 0.1 3.3e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KFX98930.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Hpt PF01627.23 KFX98931.1 - 3.5e-14 52.8 0.1 4.2e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Hpt domain Leptin PF02024.15 KFX98931.1 - 0.028 14.2 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Leptin ISG65-75 PF11727.8 KFX98931.1 - 0.13 11.4 1.2 0.26 10.5 0.3 1.7 1 1 0 2 2 2 0 Invariant surface glycoprotein DUF2838 PF10998.8 KFX98933.1 - 6e-46 155.3 7.5 6e-46 155.3 7.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1319 PF07028.11 KFX98933.1 - 0.048 13.9 0.3 0.09 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF1640 PF07798.11 KFX98933.1 - 0.074 13.1 1.7 0.11 12.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4618 PF15397.6 KFX98933.1 - 0.17 11.3 0.7 16 4.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) SMC_N PF02463.19 KFX98934.1 - 3.4e-60 203.2 0.2 1.7e-58 197.6 0.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX98934.1 - 2.4e-25 89.1 0.0 1.3e-24 86.7 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFX98934.1 - 4.8e-10 39.7 15.5 3.2e-05 23.9 0.1 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX98934.1 - 2.4e-08 34.7 22.6 2.4e-08 34.7 22.6 6.3 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.6 KFX98934.1 - 5.9e-08 32.8 10.9 5.9e-08 32.8 10.9 4.2 2 2 2 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 KFX98934.1 - 6.9e-08 32.1 0.1 1.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain HMMR_N PF15905.5 KFX98934.1 - 4.1e-05 23.2 27.1 4.1e-05 23.2 27.1 4.8 4 1 1 5 5 5 2 Hyaluronan mediated motility receptor N-terminal FPP PF05911.11 KFX98934.1 - 0.00027 19.3 16.2 0.00027 19.3 16.2 3.6 4 0 0 4 4 4 2 Filament-like plant protein, long coiled-coil SbcCD_C PF13558.6 KFX98934.1 - 0.008 16.4 0.0 0.053 13.8 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KFX98934.1 - 0.76 10.0 4.6 30 4.9 0.0 4.4 4 0 0 4 4 4 0 AAA domain Sugarporin_N PF11471.8 KFX98934.1 - 4.2 7.4 13.4 1.7 8.7 3.0 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension WD40 PF00400.32 KFX98935.1 - 1.6e-19 69.9 12.2 0.00089 20.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98935.1 - 6.6e-13 48.8 5.1 0.0002 21.6 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX98935.1 - 8.9e-07 29.0 0.1 0.004 17.1 0.1 3.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Arf PF00025.21 KFX98936.1 - 5.8e-64 214.7 0.0 9.8e-64 214.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3336 PF11815.8 KFX98936.1 - 2.4e-48 163.3 2.9 4.2e-48 162.6 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFX98936.1 - 5.3e-17 62.7 0.2 2.2e-16 60.6 0.2 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase G-alpha PF00503.20 KFX98936.1 - 2.3e-10 40.2 0.0 1.3e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFX98936.1 - 9.6e-08 31.7 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFX98936.1 - 1.4e-06 28.5 0.0 3.5e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFX98936.1 - 1.9e-06 28.0 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KFX98936.1 - 8.8e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFX98936.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2347 PF09804.9 KFX98937.1 - 6.8e-99 331.0 0.0 8.9e-99 330.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KFX98937.1 - 8.9e-53 179.5 1.6 2.3e-50 171.6 1.6 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KFX98937.1 - 0.0015 17.3 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 KFX98937.1 - 0.014 15.4 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 Stabilization of polarity axis Forkhead PF00250.18 KFX98944.1 - 4.7e-25 87.7 0.1 2.9e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 KFX98944.1 - 2.1e-10 40.8 0.1 7.1e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 KFX98944.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain Beta-lactamase PF00144.24 KFX98944.1 - 3.2 6.9 7.8 2 7.5 0.1 2.6 3 0 0 3 3 3 0 Beta-lactamase CENP-H PF05837.12 KFX98959.1 - 1.8e-35 121.8 8.9 9.5e-34 116.2 3.5 2.0 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DUF4482 PF14818.6 KFX98959.1 - 0.0087 16.9 1.0 4.2 8.2 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4482) TMCO5 PF14992.6 KFX98959.1 - 0.011 15.4 0.7 0.011 15.4 0.7 1.9 1 1 0 2 2 2 0 TMCO5 family SET PF00856.28 KFX98960.1 - 5e-18 66.1 1.5 1e-17 65.0 0.0 2.3 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.16 KFX98960.1 - 2.4e-15 57.1 6.2 2.4e-15 57.1 6.2 2.2 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 KFX98960.1 - 0.0063 16.5 1.8 0.0063 16.5 1.8 2.1 2 0 0 2 2 2 1 AWS domain Nop52 PF05997.12 KFX98961.1 - 9.8e-63 211.8 0.0 1.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMU163 PF17119.5 KFX98961.1 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DAGK_cat PF00781.24 KFX98962.1 - 2.4e-21 75.7 0.0 3.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.20 KFX98963.1 - 1.3e-96 324.3 11.2 2.2e-96 323.5 11.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFX98963.1 - 2.4e-60 202.5 1.2 5.4e-60 201.3 1.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFX98963.1 - 9.9e-57 190.4 0.0 2.9e-56 188.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFX98963.1 - 1.2e-11 44.9 8.6 9.8e-10 38.7 0.1 3.3 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX98963.1 - 3.1e-06 27.5 0.6 0.003 17.9 0.1 5.3 3 1 3 6 6 5 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KFX98963.1 - 0.00021 21.4 0.0 0.00078 19.6 0.0 2.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KFX98963.1 - 0.0092 16.2 3.3 3.3 8.2 0.0 4.4 4 0 0 4 4 3 1 HEAT repeat DUF5578 PF17741.1 KFX98963.1 - 0.018 14.5 4.3 1.8 7.9 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 KFX98963.1 - 0.046 14.1 0.4 0.16 12.3 0.4 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Phage_TAC_4 PF08748.11 KFX98963.1 - 2.1 8.7 5.8 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone HEAT_EZ PF13513.6 KFX98963.1 - 2.4 8.8 3.8 16 6.1 0.0 4.1 5 1 1 6 6 5 0 HEAT-like repeat Mago_nashi PF02792.14 KFX98964.1 - 4.6e-72 240.8 0.1 5.2e-72 240.6 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Ion_trans PF00520.31 KFX98965.1 - 7.8e-118 392.1 89.0 6.3e-40 136.9 9.0 5.0 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 KFX98965.1 - 3.1e-05 23.2 0.0 8.7e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX98965.1 - 0.00053 19.7 0.0 0.002 17.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFX98965.1 - 0.0031 17.9 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair GPHH PF16905.5 KFX98965.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated ADH_zinc_N_2 PF13602.6 KFX98966.1 - 1.8e-24 87.3 0.0 3.6e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX98966.1 - 2.5e-12 46.9 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.11 KFX98967.1 - 6.9e-10 38.5 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX98967.1 - 0.011 15.4 0.1 0.017 14.7 0.1 1.4 1 1 0 1 1 1 0 Cupin CDO_I PF05995.12 KFX98967.1 - 0.021 14.1 0.0 0.25 10.6 0.0 2.1 1 1 0 1 1 1 0 Cysteine dioxygenase type I RNA_ligase PF09414.10 KFX98968.1 - 2.9e-26 92.7 0.2 5.6e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 KFX98968.1 - 2.4e-12 47.2 0.0 2.7e-05 24.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain Y_phosphatase PF00102.27 KFX98968.1 - 7.7e-06 25.6 0.0 6.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFX98968.1 - 4.2e-05 23.6 0.0 7.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_22 PF13401.6 KFX98968.1 - 0.0031 17.8 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Y_phosphatase2 PF03162.13 KFX98968.1 - 0.0076 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_28 PF13521.6 KFX98968.1 - 0.028 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 KFX98968.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.29 KFX98968.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TauD PF02668.16 KFX98969.1 - 3.3e-58 197.6 1.1 4e-58 197.3 1.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4471 PF14740.6 KFX98969.1 - 0.13 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Acetyltransf_1 PF00583.25 KFX98970.1 - 7.4e-07 29.4 0.0 9e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX98970.1 - 0.00035 20.9 0.0 0.00052 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX98970.1 - 0.00058 19.8 0.0 0.00094 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX98970.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Fungal_trans PF04082.18 KFX98971.1 - 8.7e-11 41.3 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98971.1 - 1.3e-09 38.0 6.9 2.6e-09 37.1 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX98972.1 - 5.3e-41 140.2 0.4 6.3e-41 140.0 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98972.1 - 2.7e-32 112.2 1.1 4.1e-32 111.6 1.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX98972.1 - 8.9e-17 61.6 0.1 1.1e-16 61.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX98972.1 - 3.4e-06 26.7 0.8 3.1e-05 23.6 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX98972.1 - 1.5e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KFX98972.1 - 0.0026 17.8 0.2 0.0041 17.2 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFX98972.1 - 0.0033 16.9 0.3 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KFX98972.1 - 0.0061 16.8 0.3 0.0099 16.1 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PA PF02225.22 KFX98972.1 - 0.097 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 PA domain HEAT_2 PF13646.6 KFX98973.1 - 0.16 12.4 3.8 16 6.0 0.1 4.4 5 1 0 5 5 5 0 HEAT repeats NAD_binding_10 PF13460.6 KFX98976.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KFX98976.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_35 PF01301.19 KFX98977.1 - 7.8e-90 301.7 0.2 9.7e-90 301.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFX98977.1 - 3e-11 43.3 0.2 1.1e-10 41.4 0.2 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFX98977.1 - 3.5e-05 24.3 0.0 0.01 16.4 0.0 3.2 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain MIP PF00230.20 KFX98979.1 - 8.6e-25 87.8 11.5 1.7e-24 86.8 11.5 1.5 1 1 0 1 1 1 1 Major intrinsic protein Lactonase PF10282.9 KFX98980.1 - 1.1e-84 284.7 0.0 1.3e-84 284.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_76 PF03663.14 KFX98982.1 - 3.3e-34 119.0 17.3 4.3e-34 118.6 17.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX98982.1 - 7e-05 22.1 0.2 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 KFX98983.1 - 2.1e-09 36.8 0.0 3.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98983.1 - 9.9e-08 32.0 9.4 1.6e-07 31.3 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1116 PF06545.11 KFX98983.1 - 0.1 12.1 0.4 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) FAD_binding_3 PF01494.19 KFX98984.1 - 2.7e-10 40.0 0.2 4.2e-10 39.4 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX98984.1 - 3.8e-05 23.1 0.1 0.00024 20.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX98984.1 - 6.6e-05 22.6 0.0 6.6e-05 22.6 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX98984.1 - 0.00017 22.0 0.0 0.0016 18.9 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX98984.1 - 0.0005 20.2 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CoA_transf_3 PF02515.17 KFX98984.1 - 0.0021 17.2 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III ApbA PF02558.16 KFX98984.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KFX98984.1 - 0.055 12.7 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid6H PF17389.2 KFX98985.1 - 1.6e-10 40.8 0.1 8.4e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFX98985.1 - 5.6e-07 29.3 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KFX98985.1 - 2.8e-05 23.5 0.8 4.3e-05 22.9 0.8 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KFX98985.1 - 0.00023 20.2 0.1 0.00032 19.7 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KFX98985.1 - 0.058 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KFX98985.1 - 0.075 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain ChAPs PF09295.10 KFX98986.1 - 6.1e-152 506.2 0.0 7.5e-152 505.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KFX98986.1 - 6.6e-05 23.4 1.3 4.4 8.4 0.0 5.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX98986.1 - 0.00031 21.2 0.0 1.8 9.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98986.1 - 0.00058 19.8 0.5 4.7 7.6 1.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX98986.1 - 0.0024 18.0 1.9 0.049 13.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98986.1 - 0.046 13.8 0.6 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ORC6 PF05460.13 KFX98987.1 - 9.5 5.4 8.1 14 4.8 8.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_3 PF07859.13 KFX98988.1 - 2.5e-42 145.2 0.0 2.7e-41 141.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX98988.1 - 0.0028 16.6 0.1 0.022 13.6 0.1 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Transferase PF02458.15 KFX98989.1 - 6.4e-28 97.6 0.0 2e-26 92.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family RHH_1 PF01402.21 KFX98989.1 - 0.12 12.4 0.5 7 6.7 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Dsh_C PF12316.8 KFX98989.1 - 0.13 12.6 0.1 0.19 12.1 0.1 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Cellulase PF00150.18 KFX98991.1 - 4.5e-41 141.1 6.8 4.5e-40 137.8 4.4 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KFX98991.1 - 1e-22 80.0 6.3 6.5e-20 71.0 3.0 3.4 2 1 0 2 2 2 2 Carbohydrate binding domain X2 TPR_11 PF13414.6 KFX98992.1 - 4.2e-06 26.3 2.4 0.022 14.5 2.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KFX98992.1 - 9.3e-06 26.1 3.1 0.68 10.5 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98992.1 - 0.00031 20.9 0.2 0.066 13.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98992.1 - 0.00048 20.7 14.0 8.2 7.5 0.1 6.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98992.1 - 0.026 15.2 8.9 3 8.5 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Mak10 PF04112.13 KFX98992.1 - 0.049 13.1 0.3 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Nucleo_P87 PF07267.11 KFX98992.1 - 0.21 10.4 13.0 0.0077 15.1 4.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 TPR_1 PF00515.28 KFX98992.1 - 1.5 8.8 11.2 7.5 6.6 0.7 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat BTB PF00651.31 KFX99007.1 - 5.7e-11 42.6 0.0 1.8e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_92 PF07971.12 KFX99007.1 - 0.036 13.0 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 Phage_tail_L PF05100.12 KFX99007.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein L T2SSK PF03934.13 KFX99007.1 - 0.12 11.7 0.1 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Vps51 PF08700.11 KFX99008.1 - 4.1e-10 39.6 0.0 2e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 TetR_C_11 PF16859.5 KFX99008.1 - 0.01 16.1 4.2 0.054 13.8 4.2 2.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Nexin_C PF08628.12 KFX99008.1 - 0.17 12.5 0.6 0.65 10.6 0.6 2.0 1 0 0 1 1 1 0 Sorting nexin C terminal Bacillus_HBL PF05791.11 KFX99008.1 - 0.18 11.6 1.4 0.59 9.9 1.4 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PKcGMP_CC PF16808.5 KFX99008.1 - 0.32 10.9 3.3 9 6.2 0.3 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase G-alpha PF00503.20 KFX99016.1 - 7.6e-111 370.7 0.5 9.8e-111 370.3 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFX99016.1 - 6.9e-14 51.7 1.0 3.9e-09 36.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX99016.1 - 6.6e-05 22.4 2.5 0.0039 16.6 0.1 3.0 2 2 1 3 3 3 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFX99016.1 - 0.0041 16.5 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Roc PF08477.13 KFX99016.1 - 0.033 14.4 0.1 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFX99016.1 - 0.11 12.3 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain PALP PF00291.25 KFX99019.1 - 1.5e-19 70.5 0.4 1.7e-19 70.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rep_fac-A_C PF08646.10 KFX99020.1 - 6.2e-59 197.9 5.7 2.3e-56 189.6 0.8 3.1 2 1 1 3 3 3 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFX99020.1 - 2.2e-37 126.9 2.7 6.9e-37 125.3 0.3 2.7 3 1 1 4 4 4 1 Replication protein A OB domain Rep-A_N PF04057.12 KFX99020.1 - 8.4e-22 77.1 0.0 1.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFX99020.1 - 1.7e-19 69.5 1.2 2.3e-07 30.7 0.0 5.3 5 1 1 6 6 6 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KFX99020.1 - 0.0012 18.6 0.2 0.18 11.5 0.0 3.3 3 1 1 4 4 4 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KFX99020.1 - 0.0056 16.9 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 DUF4539 PF15072.6 KFX99020.1 - 0.056 13.5 0.0 31 4.7 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4539) Gloverin PF10793.9 KFX99020.1 - 0.072 13.0 0.2 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Gloverin-like protein VD10_N PF08476.10 KFX99020.1 - 0.12 12.1 0.0 29 4.5 0.0 2.7 2 0 0 2 2 2 0 Viral D10 N-terminal PCI PF01399.27 KFX99021.1 - 0.00028 21.3 0.0 0.0013 19.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KFX99021.1 - 0.0071 16.3 0.0 0.66 10.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Aldedh PF00171.22 KFX99022.1 - 1.1e-08 34.0 9.8 5.8e-06 25.1 6.2 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KFX99022.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) DUF3535 PF12054.8 KFX99024.1 - 6.1e-126 421.2 4.6 1.7e-124 416.4 2.8 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFX99024.1 - 4.8e-64 216.3 0.0 1.2e-63 215.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX99024.1 - 2.9e-19 69.4 0.0 7.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KFX99024.1 - 2.6e-17 61.4 15.1 0.052 13.8 0.0 10.1 10 0 0 10 10 9 6 HEAT repeat Vac14_Fab1_bd PF12755.7 KFX99024.1 - 6.4e-08 33.1 0.2 0.36 11.4 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFX99024.1 - 9.8e-06 25.9 16.0 0.0022 18.3 0.1 7.4 8 1 0 8 8 8 1 HEAT repeats CLASP_N PF12348.8 KFX99024.1 - 8.8e-05 22.2 0.0 0.13 11.8 0.0 3.2 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 KFX99024.1 - 0.01 14.9 3.9 0.19 10.8 0.2 4.0 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 KFX99024.1 - 0.016 14.9 0.8 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) TAF6_C PF07571.13 KFX99024.1 - 0.11 12.8 0.0 23 5.4 0.0 4.3 4 1 1 5 5 5 0 TAF6 C-terminal HEAT repeat domain ERCC3_RAD25_C PF16203.5 KFX99024.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Nop10p PF04135.12 KFX99031.1 - 1.1e-19 70.1 0.3 1.7e-19 69.6 0.3 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Mito_carr PF00153.27 KFX99032.1 - 2.6e-14 52.9 2.6 0.00014 21.7 0.1 4.8 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 KFX99032.1 - 0.29 11.8 0.5 0.73 10.5 0.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Fer2 PF00111.27 KFX99033.1 - 4.6e-13 48.9 1.1 6.8e-13 48.4 1.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RelB_N PF18506.1 KFX99033.1 - 0.25 11.2 4.4 0.14 11.9 1.9 1.8 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain Rrp15p PF07890.12 KFX99034.1 - 3.2e-38 131.1 12.7 3.2e-38 131.1 12.7 1.8 2 0 0 2 2 2 1 Rrp15p DUF1131 PF06572.12 KFX99034.1 - 0.077 12.7 1.6 0.12 12.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) FliL PF03748.14 KFX99034.1 - 3.7 8.2 8.5 50 4.5 5.1 2.7 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL SRP54 PF00448.22 KFX99035.1 - 5.1e-76 254.7 1.9 6.9e-76 254.3 1.2 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFX99035.1 - 9.9e-31 106.3 3.9 9.9e-31 106.3 3.9 4.2 3 2 2 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFX99035.1 - 1.8e-20 72.9 1.1 5.4e-20 71.4 1.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFX99035.1 - 1.7e-06 27.8 0.8 1.1e-05 25.1 0.9 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFX99035.1 - 3.9e-06 27.3 0.1 1.6e-05 25.3 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX99035.1 - 4e-06 27.0 0.0 8.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX99035.1 - 2e-05 24.0 0.0 2e-05 24.0 0.0 2.0 2 0 0 2 2 1 1 Zeta toxin AAA_16 PF13191.6 KFX99035.1 - 7.6e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KFX99035.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 KFX99035.1 - 0.002 17.9 0.0 0.0065 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFX99035.1 - 0.004 17.2 0.4 0.011 15.7 0.4 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 KFX99035.1 - 0.0042 16.8 0.4 0.016 14.9 0.0 2.2 3 0 0 3 3 2 1 Thymidylate kinase SRPRB PF09439.10 KFX99035.1 - 0.0049 16.3 1.4 2.7 7.4 1.7 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KFX99035.1 - 0.005 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KFX99035.1 - 0.0053 16.8 0.0 0.016 15.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KFX99035.1 - 0.0058 16.7 0.6 0.023 14.8 0.2 2.2 2 1 0 2 2 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFX99035.1 - 0.0068 16.2 0.7 0.033 14.0 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFX99035.1 - 0.012 15.8 0.2 0.034 14.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX99035.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFX99035.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.18 KFX99035.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 KFX99035.1 - 0.036 14.5 0.2 0.1 13.0 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFX99035.1 - 0.037 14.4 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KFX99035.1 - 0.037 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_31 PF13614.6 KFX99035.1 - 0.092 12.7 0.1 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain SKA2 PF16740.5 KFX99035.1 - 0.51 10.1 2.4 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 GET2 PF08690.10 KFX99035.1 - 2.5 7.7 7.1 1.1 8.8 4.3 2.0 1 1 0 1 1 1 0 GET complex subunit GET2 Glyco_hydro_45 PF02015.16 KFX99036.1 - 8.9e-44 149.9 6.2 1.1e-43 149.6 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Noc2 PF03715.13 KFX99038.1 - 8.3e-76 255.1 0.9 1.4e-75 254.3 0.0 1.9 3 0 0 3 3 3 1 Noc2p family EST1_DNA_bind PF10373.9 KFX99038.1 - 0.0019 17.8 1.1 0.32 10.4 0.0 2.7 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain Calsarcin PF05556.11 KFX99038.1 - 0.0068 16.0 2.4 0.015 14.8 2.4 1.5 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) Hid1 PF12722.7 KFX99038.1 - 0.68 8.0 5.3 0.91 7.6 5.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VPS28 PF03997.12 KFX99039.1 - 1e-70 237.3 0.2 1.2e-70 237.0 0.2 1.1 1 0 0 1 1 1 1 VPS28 protein MMM1 PF10296.9 KFX99040.1 - 2e-06 27.1 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Zip PF02535.22 KFX99065.1 - 2e-51 175.2 2.4 2.4e-51 174.9 2.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Iron_permease PF04120.12 KFX99066.1 - 5e-43 145.9 14.4 4.1e-19 68.6 0.1 4.2 4 0 0 4 4 4 4 Low affinity iron permease Ank_2 PF12796.7 KFX99067.1 - 3.4e-60 200.6 7.5 1.5e-12 47.9 0.1 6.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFX99067.1 - 5e-50 165.8 17.8 3.7e-07 30.3 0.0 10.9 10 0 0 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 KFX99067.1 - 6.5e-50 161.3 10.3 0.00014 22.0 0.0 12.2 13 1 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.6 KFX99067.1 - 1.4e-49 165.8 10.5 2.5e-13 50.2 0.0 9.1 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX99067.1 - 2.5e-41 139.2 17.1 9.5e-13 48.1 0.4 8.6 1 1 9 10 10 10 10 Ankyrin repeats (many copies) 3HCDH_RFF PF18321.1 KFX99067.1 - 0.47 10.9 10.2 40 4.7 1.8 5.0 4 2 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Cation_efflux PF01545.21 KFX99070.1 - 4.6e-51 173.4 4.8 6.6e-51 172.9 4.8 1.2 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KFX99070.1 - 0.017 14.3 0.8 0.017 14.3 0.8 2.1 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component TM140 PF14985.6 KFX99070.1 - 0.074 12.6 0.5 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 TM140 protein family Nramp PF01566.18 KFX99071.1 - 7e-57 193.0 10.3 2.4e-39 135.3 4.8 3.4 3 1 1 4 4 4 2 Natural resistance-associated macrophage protein Cation_efflux PF01545.21 KFX99071.1 - 7.3e-48 162.9 2.5 7.3e-48 162.9 2.5 2.9 3 0 0 3 3 3 1 Cation efflux family Usp PF00582.26 KFX99072.1 - 1.6e-06 28.7 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family E1-E2_ATPase PF00122.20 KFX99073.1 - 1e-41 142.5 4.3 1e-41 142.5 4.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFX99073.1 - 5.2e-24 85.7 0.0 8.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFX99073.1 - 2.8e-05 24.5 0.0 7.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFX99073.1 - 0.00091 19.0 0.3 0.09 12.5 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX99073.1 - 0.039 14.3 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFX99073.1 - 0.075 13.1 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase MTABC_N PF16185.5 KFX99073.1 - 3 7.3 8.6 0.11 12.0 0.6 2.2 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region His_biosynth PF00977.21 KFX99077.1 - 4.9e-32 111.2 0.0 5.9e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.11 KFX99077.1 - 0.16 12.2 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Ribosomal_S11 PF00411.19 KFX99077.1 - 0.16 12.4 0.0 0.59 10.6 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S11 TPR_14 PF13428.6 KFX99078.1 - 2.2e-06 28.0 15.1 7.6 7.7 0.4 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX99078.1 - 6.1e-06 26.0 8.9 7.4 7.0 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX99078.1 - 8.3e-06 25.8 0.3 4.3 7.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX99078.1 - 0.00023 21.1 9.3 3.1 8.2 0.1 5.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX99078.1 - 0.00088 19.7 10.5 1.4 9.5 0.0 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX99078.1 - 0.0016 18.2 0.9 62 3.6 0.2 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX99078.1 - 2.3 9.0 18.2 15 6.3 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat RIX1 PF08167.12 KFX99079.1 - 8e-61 205.1 0.4 2.6e-60 203.4 0.4 2.0 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Pullulanase_Ins PF18494.1 KFX99079.1 - 0.18 12.3 0.5 49 4.5 0.0 3.3 3 0 0 3 3 3 0 Pullulanase Ins domain MgtE_N PF03448.17 KFX99080.1 - 0.13 12.8 13.6 2.9e+03 -1.1 13.6 3.3 1 1 0 1 1 1 0 MgtE intracellular N domain IAT_beta PF11924.8 KFX99080.1 - 2 7.8 23.8 1.8e+04 -12.3 23.8 4.1 1 1 0 1 1 1 0 Inverse autotransporter, beta-domain YpjP PF14005.6 KFX99080.1 - 6.1 6.9 39.5 1.8e+04 -25.8 39.5 6.0 1 1 0 1 1 1 0 YpjP-like protein CH PF00307.31 KFX99081.1 - 2.2e-46 156.5 0.2 2.7e-22 79.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFX99081.1 - 2.5e-22 78.7 0.3 7.5e-22 77.2 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KFX99081.1 - 2.5e-12 46.4 0.1 5.5e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KFX99081.1 - 0.00025 20.7 0.2 0.0023 17.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.21 KFX99081.1 - 0.00073 20.0 3.7 0.21 12.1 0.0 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.32 KFX99081.1 - 0.014 14.9 0.1 0.2 11.3 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KFX99081.1 - 0.015 15.8 1.4 0.015 15.8 1.4 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.6 KFX99081.1 - 0.023 14.6 0.7 0.23 11.4 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain pair EIAV_Rev PF11129.8 KFX99081.1 - 0.18 12.0 1.5 0.41 10.8 1.5 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF4508 PF14969.6 KFX99081.1 - 0.23 11.8 1.5 8.4 6.7 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) Polysacc_deac_1 PF01522.21 KFX99082.1 - 4e-32 110.7 0.0 6.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KFX99082.1 - 4.9e-05 23.7 11.9 0.00015 22.2 11.9 1.9 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 KFX99082.1 - 0.00061 19.1 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 KFX99082.1 - 0.15 11.7 0.3 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) COX6B PF02297.17 KFX99085.1 - 1.2e-25 89.5 5.1 1.6e-25 89.2 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KFX99085.1 - 0.063 13.6 2.6 0.61 10.4 2.7 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 KFX99086.1 - 4.9e-51 172.7 12.2 5.6e-51 172.5 12.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF2070 PF09843.9 KFX99086.1 - 0.63 8.3 10.5 0.77 8.0 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3792 PF12670.7 KFX99086.1 - 5.8 7.1 13.6 1.9 8.7 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) MutS_V PF00488.21 KFX99088.1 - 7.9e-83 277.1 0.1 1.5e-82 276.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX99088.1 - 1.4e-35 123.3 1.2 4e-35 121.8 1.2 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KFX99088.1 - 2.4e-20 73.2 0.0 7.2e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 KFX99088.1 - 6.3e-19 68.3 0.6 2.8e-18 66.2 0.0 2.4 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.18 KFX99088.1 - 3.8e-17 62.4 2.0 1.4e-16 60.6 2.0 2.1 1 0 0 1 1 1 1 MutS family domain IV Peptidase_M16 PF00675.20 KFX99088.1 - 0.077 13.0 0.2 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) TetR_C_7 PF14246.6 KFX99088.1 - 0.08 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain AAA PF00004.29 KFX99089.1 - 4.7e-52 175.9 0.0 3.3e-43 147.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KFX99089.1 - 1.5e-28 99.0 0.1 4.1e-28 97.6 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KFX99089.1 - 1.2e-15 57.0 0.0 4.5e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KFX99089.1 - 7.8e-10 39.4 5.6 0.00024 21.6 0.4 4.1 2 2 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KFX99089.1 - 3.8e-07 30.2 0.6 0.002 18.1 0.0 3.2 3 0 0 3 3 3 2 NACHT domain RuvB_N PF05496.12 KFX99089.1 - 8.3e-06 25.6 0.0 0.009 15.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFX99089.1 - 1.3e-05 25.2 0.1 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFX99089.1 - 6.6e-05 22.9 0.2 0.59 10.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KFX99089.1 - 8e-05 22.2 0.0 0.0086 15.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KFX99089.1 - 8.9e-05 23.0 0.0 0.72 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFX99089.1 - 0.00015 22.1 1.4 1.7 9.0 0.1 4.0 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFX99089.1 - 0.00026 20.8 0.2 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KFX99089.1 - 0.00045 19.6 0.2 0.31 10.3 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.6 KFX99089.1 - 0.00051 20.2 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KFX99089.1 - 0.0026 17.4 1.0 0.45 10.0 0.1 3.3 2 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFX99089.1 - 0.0028 18.0 0.0 4.1 7.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 KFX99089.1 - 0.0034 17.5 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFX99089.1 - 0.0036 17.5 0.0 0.073 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KFX99089.1 - 0.0066 16.5 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFX99089.1 - 0.0067 16.7 1.1 7.6 6.8 0.0 3.7 5 0 0 5 5 3 0 AAA domain ABC_tran PF00005.27 KFX99089.1 - 0.007 16.9 0.1 3.6 8.1 0.1 2.9 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.21 KFX99089.1 - 0.0095 15.3 0.3 0.15 11.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KFX99089.1 - 0.01 15.0 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX99089.1 - 0.015 15.0 0.0 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 KFX99089.1 - 0.022 13.9 0.0 0.82 8.8 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_17 PF13207.6 KFX99089.1 - 0.028 14.8 0.2 1.4 9.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 KFX99089.1 - 0.052 13.7 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase APS_kinase PF01583.20 KFX99089.1 - 0.075 12.9 0.1 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KFX99089.1 - 0.086 12.1 0.3 0.55 9.4 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 KFX99089.1 - 0.12 12.2 0.1 2 8.2 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KFX99089.1 - 0.12 12.1 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KFX99089.1 - 0.19 11.8 0.0 9.9 6.3 0.0 3.2 4 0 0 4 4 3 0 Torsin MCM PF00493.23 KFX99090.1 - 1.3e-103 344.9 0.0 2.4e-103 344.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFX99090.1 - 2.2e-30 105.1 0.2 4.7e-30 104.0 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFX99090.1 - 3.9e-20 72.4 2.8 1e-19 71.1 2.8 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KFX99090.1 - 2.3e-19 69.6 1.1 6.4e-19 68.2 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFX99090.1 - 9.2e-08 31.7 0.0 9e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFX99090.1 - 3.5e-06 27.1 0.0 1e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2040 PF09745.9 KFX99090.1 - 0.037 14.1 1.0 0.14 12.2 1.0 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) RecX PF02631.16 KFX99090.1 - 0.086 13.3 1.5 0.47 10.9 0.2 2.3 2 0 0 2 2 2 0 RecX family Mg_chelatase_C PF13335.6 KFX99090.1 - 0.095 13.3 2.7 0.2 12.3 1.0 2.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KFX99090.1 - 0.11 12.3 0.0 0.39 10.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRS1 PF04939.12 KFX99091.1 - 4.7e-58 195.6 2.0 5.5e-58 195.4 2.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PH PF00169.29 KFX99092.1 - 7.9e-09 36.0 0.1 1.3e-08 35.3 0.1 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 KFX99092.1 - 0.013 15.9 1.4 0.063 13.7 1.4 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_S55 PF05580.12 KFX99092.1 - 0.029 14.3 0.1 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 PH_9 PF15410.6 KFX99092.1 - 0.041 14.2 0.3 0.074 13.4 0.3 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 KFX99095.1 - 0.0068 17.2 0.2 4.4 8.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Bim_N PF06773.11 KFX99095.1 - 1.7 8.4 6.5 18 5.1 0.1 3.1 3 0 0 3 3 3 0 Bim protein N-terminus HRXXH PF13933.6 KFX99104.1 - 5e-95 317.7 0.0 6.1e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KFX99104.1 - 1.4e-05 25.7 0.0 2.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 KFX99105.1 - 3.6e-40 138.2 11.9 3.6e-40 138.2 11.9 2.5 2 1 0 2 2 2 1 ZIP Zinc transporter Arf PF00025.21 KFX99118.1 - 3.1e-76 254.7 0.1 4.3e-76 254.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFX99118.1 - 6.2e-14 52.2 0.0 9.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX99118.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFX99118.1 - 1.7e-12 47.3 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFX99118.1 - 4.1e-12 45.9 0.9 3.5e-09 36.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFX99118.1 - 4.8e-10 39.2 0.0 7.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX99118.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFX99118.1 - 0.03 13.6 0.2 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 KFX99119.1 - 3e-36 125.1 0.0 3.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ACT_3 PF10000.9 KFX99119.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF1627 PF07789.12 KFX99119.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Ost5 PF05251.12 KFX99120.1 - 4.6 7.6 8.3 0.62 10.4 1.8 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Fe_hyd_lg_C PF02906.14 KFX99121.1 - 1.6e-56 191.7 0.0 3.2e-56 190.7 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 KFX99122.1 - 1.3e-06 29.1 1.6 1.3e-06 29.1 1.6 3.5 3 1 0 3 3 3 1 SUZ domain 2-Hacid_dh_C PF02826.19 KFX99124.1 - 5.4e-54 182.2 0.0 2.4e-53 180.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX99124.1 - 6.2e-17 61.5 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain zf-H2C2_2 PF13465.6 KFX99124.1 - 1.5e-05 25.2 0.5 1.5e-05 25.2 0.5 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFX99124.1 - 4.4e-05 23.7 8.7 9e-05 22.7 0.2 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KFX99124.1 - 0.00017 22.2 3.9 0.6 10.8 2.0 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFX99124.1 - 0.00026 20.9 0.2 0.44 10.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger NAD_binding_2 PF03446.15 KFX99124.1 - 0.0011 19.2 0.3 0.0019 18.4 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2_4 PF13894.6 KFX99124.1 - 0.0051 17.5 6.8 0.083 13.8 0.2 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFX99124.1 - 0.009 15.8 0.3 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFX99124.1 - 0.14 12.9 0.8 6.5 7.4 0.4 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Aldo_ket_red PF00248.21 KFX99125.1 - 1.2e-56 192.1 0.0 1.3e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KFX99126.1 - 5.5e-23 80.8 7.2 6.9e-07 29.9 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99126.1 - 8.8e-16 58.0 0.1 0.099 13.0 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX99126.1 - 0.00014 20.6 0.1 0.017 13.8 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFX99126.1 - 0.0071 14.9 0.0 1.5 7.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.6 KFX99126.1 - 0.0074 15.9 0.1 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain JmjC PF02373.22 KFX99134.1 - 1.8e-09 38.0 0.2 5.6e-09 36.4 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KFX99134.1 - 1.6e-07 31.4 9.7 1.6e-07 31.4 9.7 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KFX99134.1 - 0.017 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 KFX99135.1 - 3.5e-43 147.7 22.0 3.5e-43 147.7 22.0 1.4 2 0 0 2 2 2 1 UbiA prenyltransferase family UPF0061 PF02696.14 KFX99137.1 - 1.9e-126 422.6 0.0 1e-125 420.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized ACR, YdiU/UPF0061 family SesA PF17107.5 KFX99137.1 - 1.4e-32 112.4 0.6 3.8e-32 111.0 0.6 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 KFX99137.1 - 1.5e-19 70.4 0.0 1.5e-08 35.1 0.1 4.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX99137.1 - 2.9e-16 57.9 0.6 0.0061 17.0 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 KFX99137.1 - 1.8e-14 53.9 0.0 6e-07 29.9 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFX99137.1 - 2.7e-13 49.7 2.2 0.14 12.7 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KFX99137.1 - 1.5e-11 44.3 0.6 7.9e-05 22.9 0.1 4.6 3 1 0 4 4 4 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 KFX99137.1 - 0.025 14.8 0.0 0.16 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain MARVEL PF01284.23 KFX99137.1 - 0.029 14.4 0.9 0.066 13.2 0.9 1.6 1 0 0 1 1 1 0 Membrane-associating domain Ploopntkinase3 PF18751.1 KFX99137.1 - 0.033 14.1 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 KFX99137.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldo_ket_red PF00248.21 KFX99138.1 - 7.3e-46 156.7 0.0 1.2e-44 152.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.19 KFX99138.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Striatin PF08232.12 KFX99142.1 - 9.8e-42 143.2 0.6 9.8e-42 143.2 0.6 2.7 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 KFX99142.1 - 4.6e-26 90.5 17.3 7.9e-05 23.4 0.1 7.5 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99142.1 - 5.5e-06 26.6 0.0 1.3 9.3 0.0 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF5320 PF17253.2 KFX99142.1 - 0.11 13.6 5.4 0.24 12.5 3.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) ABC2_membrane PF01061.24 KFX99143.1 - 4.4e-86 287.6 60.1 4.9e-45 153.5 18.1 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFX99143.1 - 1.7e-39 135.4 0.0 8.6e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX99143.1 - 4.6e-35 119.4 10.3 1.7e-30 104.8 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX99143.1 - 8.1e-17 61.6 0.0 3.6e-16 59.5 0.0 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KFX99143.1 - 3.6e-06 27.2 0.3 0.0085 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX99143.1 - 1.2e-05 25.2 0.6 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFX99143.1 - 2e-05 25.0 0.4 0.023 15.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX99143.1 - 5.2e-05 22.9 0.5 0.0015 18.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFX99143.1 - 0.0011 18.7 1.4 0.064 13.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFX99143.1 - 0.002 17.6 0.0 0.083 12.3 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX99143.1 - 0.0021 17.9 0.4 2.8 7.6 0.1 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFX99143.1 - 0.0074 16.8 0.1 0.4 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX99143.1 - 0.008 16.2 0.0 6.8 6.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KFX99143.1 - 0.011 15.3 2.6 0.45 10.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFX99143.1 - 0.026 14.9 0.1 1.2 9.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX99143.1 - 0.062 13.0 0.3 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFX99143.1 - 0.1 12.9 3.6 4.4 7.6 0.5 3.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX99143.1 - 0.14 12.1 3.2 9.8 6.1 0.6 2.7 2 0 0 2 2 2 0 NACHT domain DUF1772 PF08592.11 KFX99143.1 - 8.4 6.7 7.0 2.1e+02 2.2 0.0 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) WSC PF01822.19 KFX99144.1 - 1.6e-40 137.1 18.9 5.6e-20 71.3 9.6 2.7 2 0 0 2 2 2 2 WSC domain Amidase PF01425.21 KFX99144.1 - 6.7 5.6 8.5 11 4.8 8.5 1.3 1 0 0 1 1 1 0 Amidase PIG-P PF08510.12 KFX99145.1 - 1.8e-51 173.1 0.3 1.8e-51 173.1 0.3 2.1 2 0 0 2 2 2 1 PIG-P MFS_1 PF07690.16 KFX99145.1 - 9.9e-37 126.7 55.4 9.9e-37 126.7 55.4 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily Pex14_N PF04695.13 KFX99145.1 - 0.013 16.1 1.0 0.095 13.3 0.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Acetyltransf_1 PF00583.25 KFX99146.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX99146.1 - 0.017 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF664 PF04978.12 KFX99146.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF664) DUF3328 PF11807.8 KFX99147.1 - 4.1e-23 82.3 0.1 1.1e-22 80.9 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GMC_oxred_N PF00732.19 KFX99148.1 - 6.1e-63 213.0 0.0 7.5e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX99148.1 - 1.1e-37 129.7 0.0 1.9e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFX99148.1 - 5.4e-05 22.4 0.2 0.00014 21.0 0.0 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX99148.1 - 0.00042 19.5 0.1 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFX99148.1 - 0.00049 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFX99148.1 - 0.0019 17.5 0.1 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX99148.1 - 0.0023 17.6 0.0 0.0095 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX99148.1 - 0.0045 17.2 0.0 0.0045 17.2 0.0 2.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX99148.1 - 0.0098 15.2 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX99148.1 - 0.017 13.9 0.2 0.32 9.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 KFX99148.1 - 0.1 12.9 0.1 0.4 11.0 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF3328 PF11807.8 KFX99150.1 - 1.8e-52 178.3 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.25 KFX99151.1 - 1.3e-08 34.5 0.0 2.8e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFX99151.1 - 0.0026 17.7 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Arb2 PF09757.9 KFX99152.1 - 2.7e-92 308.6 0.0 3.5e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KFX99152.1 - 7.1e-83 278.6 0.0 1.2e-82 277.8 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_61 PF03443.14 KFX99153.1 - 1.7e-54 184.9 0.2 2.4e-54 184.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFX99153.1 - 6.1e-06 26.1 6.6 2e-05 24.5 6.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 KFX99154.1 - 1.2e-66 224.6 0.1 1.4e-66 224.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT_N PF17100.5 KFX99155.1 - 1.8e-23 83.6 1.3 4.5e-23 82.3 1.3 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 KFX99155.1 - 4.2e-20 72.1 0.1 2.2e-08 34.5 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99155.1 - 1.7e-16 60.4 2.5 1.4e-08 35.1 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX99155.1 - 6.4e-16 58.2 0.8 4e-09 36.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX99155.1 - 8.5e-12 44.2 0.2 6.4e-05 23.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFX99155.1 - 4.8e-09 36.3 0.4 0.00015 22.1 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat TPR_12 PF13424.6 KFX99155.1 - 1.2e-06 28.7 6.5 0.059 13.7 0.1 4.4 3 1 0 4 4 4 3 Tetratricopeptide repeat NACHT PF05729.12 KFX99155.1 - 5e-06 26.5 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFX99155.1 - 1.8e-05 25.0 0.0 0.00029 21.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX99155.1 - 0.0024 18.3 0.0 0.0078 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFX99155.1 - 0.032 14.7 0.0 0.15 12.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_2 PF07719.17 KFX99155.1 - 0.051 13.7 0.0 1.5e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CDC45 PF02724.14 KFX99155.1 - 6.2 5.0 10.3 13 3.9 10.3 1.4 1 0 0 1 1 1 0 CDC45-like protein TPR_10 PF13374.6 KFX99155.1 - 6.8 6.7 9.3 28 4.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1325 PF07039.11 KFX99156.1 - 3.3e-34 117.8 0.0 4.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 KFX99156.1 - 0.045 13.8 0.2 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) PIF1 PF05970.14 KFX99163.1 - 3e-58 197.7 0.3 4.1e-45 154.5 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KFX99163.1 - 1.1e-23 83.9 0.0 2.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX99163.1 - 5.5e-12 46.3 0.0 1.1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFX99163.1 - 2.6e-05 24.5 0.0 6.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KFX99163.1 - 9.7e-05 20.5 0.1 0.00079 17.5 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 KFX99163.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KFX99163.1 - 0.00041 20.1 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFX99163.1 - 0.00069 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 KFX99163.1 - 0.006 15.7 0.1 0.0099 15.0 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KFX99163.1 - 0.0089 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX99163.1 - 0.01 16.3 0.1 0.033 14.6 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KFX99163.1 - 0.018 14.8 0.1 3.6 7.3 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFX99163.1 - 0.022 14.0 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 KFX99163.1 - 0.03 14.1 0.1 0.11 12.3 0.1 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RNA_helicase PF00910.22 KFX99163.1 - 0.04 14.3 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KFX99163.1 - 0.044 13.0 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KFX99163.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KFX99163.1 - 0.065 12.6 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.15 KFX99163.1 - 0.074 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KFX99163.1 - 0.086 12.3 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 KFX99163.1 - 0.1 12.0 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KFX99163.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KFX99163.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 KFX99163.1 - 0.13 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KFX99163.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF5605 PF18310.1 KFX99163.1 - 0.19 11.7 0.0 0.77 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) RRM_1 PF00076.22 KFX99164.1 - 3.3e-58 193.4 0.0 8.4e-20 70.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX99164.1 - 7e-10 38.6 0.0 0.0002 21.0 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX99164.1 - 5.5e-08 32.6 0.0 0.018 14.9 0.0 3.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFX99164.1 - 1.9e-06 27.8 0.3 0.13 12.3 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 KFX99164.1 - 0.00097 19.3 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_7 PF16367.5 KFX99164.1 - 0.0026 17.8 0.1 2.9 8.1 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KFX99164.1 - 0.02 14.9 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM PF05172.13 KFX99164.1 - 0.036 14.0 0.0 64 3.6 0.0 3.3 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KFX99164.1 - 0.1 12.7 0.1 33 4.6 0.1 3.3 3 1 0 3 3 3 0 Limkain b1 Med2 PF11214.8 KFX99165.1 - 0.003 17.7 0.5 0.024 14.8 0.1 2.5 2 0 0 2 2 2 1 Mediator complex subunit 2 UPF0121 PF03661.13 KFX99180.1 - 3.7e-09 36.3 0.0 4.4e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Synapsin_N PF10581.9 KFX99180.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Synapsin N-terminal Palm_thioest PF02089.15 KFX99181.1 - 1.9e-32 113.1 0.4 2.2e-32 112.9 0.4 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cyclin_N PF00134.23 KFX99182.1 - 1.5e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA-synt_2b PF00587.25 KFX99183.1 - 4e-12 46.5 0.0 5.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFX99183.1 - 7.2e-10 39.1 0.8 1.7e-09 37.9 0.8 1.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DIL PF01843.19 KFX99184.1 - 7.4e-33 112.9 0.6 1.5e-32 112.0 0.6 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KFX99184.1 - 2.4e-11 44.1 0.0 9.6e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99184.1 - 1.8e-10 41.2 0.0 3.8e-06 27.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX99184.1 - 3.6e-09 36.7 0.0 3.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX99184.1 - 5.3e-08 33.0 0.0 0.04 14.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFX99184.1 - 9.3e-06 25.6 0.0 0.64 10.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat DUF4962 PF16332.5 KFX99184.1 - 0.014 14.0 0.1 0.022 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Oxidored_FMN PF00724.20 KFX99185.1 - 5.6e-91 305.3 0.0 6.4e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HK_sensor PF16750.5 KFX99185.1 - 0.19 12.1 0.1 7.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase Vps5 PF09325.10 KFX99186.1 - 0.023 14.2 10.0 0.15 11.6 6.1 2.3 2 0 0 2 2 2 0 Vps5 C terminal like IFP_35_N PF07334.13 KFX99186.1 - 0.19 11.8 0.2 0.19 11.8 0.2 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4686 PF15742.5 KFX99186.1 - 0.38 9.8 14.1 1.6 7.8 6.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4686) PIN_2 PF10130.9 KFX99186.1 - 0.39 11.0 5.4 0.12 12.6 2.0 1.9 2 0 0 2 2 2 0 PIN domain PKcGMP_CC PF16808.5 KFX99186.1 - 0.39 10.6 6.0 19 5.2 0.0 3.9 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AbiH PF14253.6 KFX99186.1 - 0.65 9.8 2.8 1.4 8.7 2.7 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF4446 PF14584.6 KFX99186.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) LUC7 PF03194.15 KFX99186.1 - 3.2 7.4 10.9 2.5 7.7 6.4 2.2 2 0 0 2 2 2 0 LUC7 N_terminus SlyX PF04102.12 KFX99186.1 - 3.6 8.3 11.6 33 5.2 0.1 3.7 3 1 0 3 3 3 0 SlyX ADIP PF11559.8 KFX99186.1 - 5.6 7.0 18.2 0.78 9.8 0.4 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SOGA PF11365.8 KFX99186.1 - 8.4 7.6 9.0 4.2 8.6 1.1 3.4 2 1 1 3 3 3 0 Protein SOGA Cytochrom_B561 PF03188.16 KFX99187.1 - 2.2e-15 57.0 6.6 4.3e-15 56.0 6.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3425 PF11905.8 KFX99187.1 - 1.3e-06 28.4 0.7 2.5e-06 27.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFX99187.1 - 0.0038 17.3 5.5 0.0066 16.5 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF418 PF04235.12 KFX99187.1 - 0.28 11.1 9.5 0.059 13.3 4.6 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF418) Ni_hydr_CYTB PF01292.20 KFX99187.1 - 0.81 9.3 11.2 13 5.3 11.3 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 KFX99187.1 - 1.3 9.2 13.3 1.1 9.4 8.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF4267 PF14087.6 KFX99188.1 - 3.3e-05 23.9 4.5 5.9e-05 23.1 4.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) zf-RRPl_C4 PF17026.5 KFX99189.1 - 0.0014 18.7 2.6 0.095 12.8 0.1 2.6 1 1 1 2 2 2 2 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFX99189.1 - 0.057 14.2 5.6 4.2 8.2 0.9 2.5 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 KFX99189.1 - 0.22 11.6 7.3 2.6 8.2 1.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon IQCJ-SCHIP1 PF15157.6 KFX99189.1 - 1.5 8.7 5.2 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif FYVE PF01363.21 KFX99189.1 - 3.3 7.9 8.5 1e+02 3.1 8.5 2.7 1 1 0 1 1 1 0 FYVE zinc finger Dynamitin PF04912.14 KFX99192.1 - 1.5e-06 27.9 0.3 1.6e-06 27.7 0.3 1.0 1 0 0 1 1 1 1 Dynamitin SET PF00856.28 KFX99195.1 - 8.5e-06 26.3 0.0 3.3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFX99195.1 - 0.00081 19.4 7.4 0.00081 19.4 7.4 2.3 2 0 0 2 2 2 1 MYND finger C1_1 PF00130.22 KFX99195.1 - 1.5 8.7 6.9 0.36 10.7 1.7 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glucosamine_iso PF01182.20 KFX99196.1 - 5.5e-70 235.8 0.0 6.2e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PP2C PF00481.21 KFX99205.1 - 2e-83 280.0 0.0 3.4e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C ACT PF01842.25 KFX99229.1 - 5.3e-14 51.7 0.1 1.1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 KFX99229.1 - 5.4e-14 52.2 0.0 6.1e-13 48.8 0.0 2.5 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KFX99229.1 - 5.8e-08 32.5 0.0 9.9e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF3712 PF12505.8 KFX99230.1 - 9.6e-09 35.6 3.9 6.5e-07 29.7 0.1 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KFX99230.1 - 0.0084 16.6 3.0 26 5.4 0.0 4.8 5 0 0 5 5 5 1 Late embryogenesis abundant protein OTCace_N PF02729.21 KFX99231.1 - 9.2e-46 155.5 0.2 1.7e-45 154.6 0.2 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFX99231.1 - 6.7e-42 143.2 0.0 1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Mpp10 PF04006.12 KFX99232.1 - 7.9e-111 371.4 75.7 3.2e-110 369.4 75.7 1.7 1 1 0 1 1 1 1 Mpp10 protein Peptidase_S64 PF08192.11 KFX99232.1 - 0.96 7.9 3.1 2.5 6.5 3.1 1.6 1 0 0 1 1 1 0 Peptidase family S64 Oxidored_q6 PF01058.22 KFX99233.1 - 4.2e-22 78.4 0.0 6.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.18 KFX99234.1 - 4.3e-06 26.7 6.2 9e-06 25.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX99234.1 - 0.0023 17.0 0.0 0.005 15.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-HYPF PF07503.12 KFX99234.1 - 1.7 8.5 6.4 3.2 7.6 0.7 2.8 2 0 0 2 2 2 0 HypF finger SART-1 PF03343.13 KFX99236.1 - 4.6e-194 646.6 70.6 5.3e-194 646.4 70.6 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 KFX99237.1 - 7.1e-100 334.9 0.0 8.5e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KFX99237.1 - 1.5e-31 108.2 0.5 4.1e-31 106.8 0.5 1.8 1 0 0 1 1 1 1 Starch binding domain zinc_ribbon_6 PF14599.6 KFX99239.1 - 8e-26 89.8 0.6 1.2e-25 89.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon RNA_pol_3_Rpc31 PF11705.8 KFX99239.1 - 0.008 16.5 6.9 0.0095 16.2 6.9 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 KFX99239.1 - 0.032 12.5 1.3 0.028 12.7 1.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Stc1 PF12898.7 KFX99239.1 - 0.067 13.7 0.2 0.1 13.1 0.2 1.2 1 0 0 1 1 1 0 Stc1 domain NOA36 PF06524.12 KFX99239.1 - 0.17 11.2 16.7 0.86 8.9 12.7 2.0 2 0 0 2 2 2 0 NOA36 protein Rubredoxin_2 PF18073.1 KFX99239.1 - 0.23 11.2 0.6 0.66 9.7 0.6 1.7 1 1 0 1 1 1 0 Rubredoxin metal binding domain DUF4637 PF15470.6 KFX99239.1 - 2.9 7.6 6.4 4.9 6.9 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3984 PF13136.6 KFX99240.1 - 4.4e-56 190.7 26.2 7e-48 163.7 20.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3984) DENN PF02141.21 KFX99242.1 - 2.3e-57 194.0 0.0 4.2e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFX99242.1 - 3.2e-13 50.2 0.0 1.2e-12 48.4 0.0 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFX99242.1 - 4.6e-13 48.9 0.8 1.2e-12 47.6 0.1 2.2 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 KFX99242.1 - 3.7e-05 23.9 4.5 7e-05 23.1 4.5 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KFX99242.1 - 0.0044 16.9 4.1 0.0076 16.1 4.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KFX99242.1 - 0.054 13.4 2.5 0.11 12.4 2.5 1.5 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.11 KFX99242.1 - 6.4 6.8 5.3 16 5.5 5.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LPMO_10 PF03067.15 KFX99248.1 - 2.8e-08 34.6 1.0 3.4e-08 34.4 1.0 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Fungal_trans_2 PF11951.8 KFX99249.1 - 8.1e-07 28.2 0.7 1e-06 27.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99249.1 - 3.7e-06 27.0 9.8 7.1e-06 26.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 KFX99249.1 - 0.044 14.1 0.2 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF899 PF05988.12 KFX99249.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) RTA1 PF04479.13 KFX99250.1 - 1.1e-28 100.3 7.3 1.1e-28 100.3 7.3 2.4 2 1 1 3 3 3 1 RTA1 like protein CrtC PF07143.11 KFX99250.1 - 0.1 13.2 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain p450 PF00067.22 KFX99251.1 - 4.4e-53 180.7 0.0 5.6e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1471 PF07338.13 KFX99251.1 - 0.059 13.3 0.1 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) TRI12 PF06609.13 KFX99253.1 - 5.5e-26 91.1 26.0 6.6e-26 90.9 26.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX99253.1 - 4.3e-21 75.2 53.0 9.6e-21 74.1 48.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4141 PF13605.6 KFX99253.1 - 0.091 12.0 0.9 0.34 10.2 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Zn_clus PF00172.18 KFX99255.1 - 1.5e-08 34.6 10.9 2.9e-08 33.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX99255.1 - 1.8e-07 30.3 0.6 2.5e-07 29.9 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Secretin_N PF03958.17 KFX99256.1 - 0.22 12.0 3.4 9.1 6.8 0.0 3.8 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain IBR PF01485.21 KFX99261.1 - 5.1e-18 65.1 30.4 9.6e-12 45.0 1.6 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KFX99261.1 - 2.6e-17 63.1 0.0 5.2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KFX99261.1 - 0.00012 22.0 5.8 0.00012 22.0 5.8 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 KFX99261.1 - 0.00015 22.0 5.0 0.00015 22.0 5.0 4.3 4 1 1 5 5 5 2 Ring finger domain zf-C3HC4 PF00097.25 KFX99261.1 - 0.0049 16.7 4.9 0.0049 16.7 4.9 4.4 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX99261.1 - 0.0051 16.7 5.8 0.0051 16.7 5.8 4.0 3 1 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX99261.1 - 0.019 14.8 4.7 0.019 14.8 4.7 4.0 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 DUF1244 PF06844.11 KFX99261.1 - 0.34 11.1 2.9 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) FYVE PF01363.21 KFX99261.1 - 0.92 9.7 25.4 7 6.9 7.3 3.5 2 1 0 2 2 2 0 FYVE zinc finger NDT80_PhoG PF05224.12 KFX99262.1 - 1.1e-30 107.2 0.0 3.4e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.10 KFX99263.1 - 7.2e-22 77.4 0.0 2e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) tRNA-synt_1 PF00133.22 KFX99264.1 - 1.1e-55 189.0 0.0 1.5e-21 76.3 0.1 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFX99264.1 - 5.1e-42 143.5 0.0 8.5e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KFX99264.1 - 3.6e-27 95.1 0.0 1.7e-18 66.6 0.0 4.4 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFX99264.1 - 1.2e-11 44.8 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFX99264.1 - 0.0068 15.8 0.0 0.25 10.7 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 KFX99264.1 - 1.2 8.7 2.9 8.4 6.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain AA_permease_2 PF13520.6 KFX99265.1 - 5.9e-62 209.9 35.1 8e-62 209.4 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX99265.1 - 2.1e-26 92.6 26.2 2.1e-26 92.6 26.2 2.0 2 0 0 2 2 2 2 Amino acid permease YfzA PF14118.6 KFX99266.1 - 0.53 10.7 3.0 0.38 11.2 0.6 2.1 2 0 0 2 2 2 0 YfzA-like protein Peptidase_M48_N PF16491.5 KFX99266.1 - 1.3 8.9 12.0 0.029 14.3 2.5 2.3 2 1 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices TraL PF07178.11 KFX99266.1 - 5 7.7 8.1 20 5.7 0.3 3.0 2 1 1 3 3 3 0 TraL protein Glyco_hydro_43 PF04616.14 KFX99267.1 - 7.2e-13 48.5 0.3 1.5e-12 47.4 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C3HC4 PF00097.25 KFX99268.1 - 7.2e-09 35.4 3.9 7.2e-09 35.4 3.9 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX99268.1 - 9.6e-08 31.9 2.7 9.6e-08 31.9 2.7 3.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX99268.1 - 1.3e-06 28.2 3.7 1.3e-06 28.2 3.7 4.0 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX99268.1 - 5e-06 26.7 4.3 5e-06 26.7 4.3 3.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 KFX99268.1 - 2.2e-05 24.2 0.9 2.2e-05 24.2 0.9 3.2 3 1 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFX99268.1 - 3.7e-05 23.6 3.4 3.7e-05 23.6 3.4 4.8 4 1 0 4 4 4 1 zinc-RING finger domain GAGA PF09237.11 KFX99268.1 - 0.00042 20.1 1.6 0.0066 16.2 0.6 2.8 2 0 0 2 2 2 1 GAGA factor zf-C3HC4_4 PF15227.6 KFX99268.1 - 0.0066 16.6 5.3 0.0066 16.6 5.3 4.1 3 3 1 4 4 4 1 zinc finger of C3HC4-type, RING Tmpp129 PF10272.9 KFX99268.1 - 0.016 14.5 1.4 0.038 13.3 1.4 1.5 1 0 0 1 1 1 0 Putative transmembrane protein precursor FAD_binding_3 PF01494.19 KFX99270.1 - 3.1e-29 102.3 0.0 6e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KFX99270.1 - 5.6e-05 22.3 0.0 0.021 13.9 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 KFX99270.1 - 0.0024 17.5 0.1 0.72 9.4 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX99270.1 - 0.0027 16.8 0.0 0.4 9.7 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX99270.1 - 0.0079 15.5 0.1 1.1 8.4 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX99270.1 - 0.025 15.1 0.0 9.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 KFX99270.1 - 0.026 14.3 1.6 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain NAD_binding_8 PF13450.6 KFX99270.1 - 0.032 14.5 0.1 0.076 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.6 KFX99271.1 - 3.3e-34 118.4 0.0 3.8e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX99271.1 - 1.7e-08 34.3 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX99271.1 - 1.8e-07 30.9 0.1 2.5e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KFX99271.1 - 0.084 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KFX99271.1 - 0.1 12.9 0.2 0.6 10.4 0.0 2.4 3 1 0 3 3 3 0 TrkA-N domain RmlD_sub_bind PF04321.17 KFX99271.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans PF04082.18 KFX99272.1 - 9.6e-12 44.5 0.1 2.1e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99272.1 - 5.4e-06 26.4 11.0 1.1e-05 25.4 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_L_D2 PF02786.17 KFX99274.1 - 1.7e-58 197.6 0.0 2.4e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFX99274.1 - 8.1e-31 106.3 0.0 1.4e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFX99274.1 - 5.7e-27 94.4 0.0 1.1e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFX99274.1 - 2.1e-10 40.3 2.8 5.7e-10 38.9 2.8 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX99274.1 - 4.3e-07 29.7 0.0 8.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX99274.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFX99274.1 - 0.00032 20.8 0.0 0.00068 19.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 KFX99274.1 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 KFX99274.1 - 0.003 17.3 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 KFX99274.1 - 0.017 15.1 0.1 0.047 13.6 0.1 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Carboxyl_trans PF01039.22 KFX99275.1 - 8e-72 242.5 0.0 1e-71 242.1 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MFS_1 PF07690.16 KFX99276.1 - 2.4e-34 118.8 28.2 3.6e-34 118.2 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 KFX99276.1 - 2 8.5 5.6 1.8 8.7 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage P21 holin S Fungal_trans PF04082.18 KFX99277.1 - 1.7e-24 86.3 0.2 2.6e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 KFX99278.1 - 4.4e-47 160.6 0.0 6.7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX99278.1 - 2.6e-05 25.1 0.0 5.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain bZIP_2 PF07716.15 KFX99281.1 - 6.8e-05 22.9 25.0 0.00069 19.7 25.0 2.3 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFX99281.1 - 9.1e-05 22.5 18.1 0.00016 21.7 18.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFX99281.1 - 0.056 14.0 14.8 0.099 13.2 14.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor GrpE PF01025.19 KFX99281.1 - 0.17 11.5 0.1 0.17 11.5 0.1 2.6 2 1 0 2 2 2 0 GrpE Cytochrom_B558a PF05038.13 KFX99281.1 - 1 8.9 2.4 1.6 8.3 2.4 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit APG6_N PF17675.1 KFX99281.1 - 2.8 8.5 17.6 29 5.2 17.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region NAM-associated PF14303.6 KFX99281.1 - 9.8 6.9 18.7 0.44 11.3 12.0 2.0 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain DUF1761 PF08570.10 KFX99283.1 - 4.1e-28 98.2 4.2 4.6e-28 98.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.9 KFX99283.1 - 2.5 8.2 6.4 2 8.5 0.4 3.1 1 1 2 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CTP_transf_like PF01467.26 KFX99284.1 - 0.034 14.4 0.1 6 7.0 0.0 2.9 1 1 1 3 3 3 0 Cytidylyltransferase-like Oxysterol_BP PF01237.18 KFX99284.1 - 0.65 8.8 5.9 0.95 8.2 5.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Glyco_hydro_15 PF00723.21 KFX99286.1 - 2.1e-21 76.3 0.0 3.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 6PGD PF00393.19 KFX99300.1 - 1.3e-127 425.1 0.0 1.6e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFX99300.1 - 2.3e-34 118.9 0.0 3.6e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HPS3_Mid PF14762.6 KFX99300.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region ANT PF03374.14 KFX99300.1 - 0.17 12.2 0.2 9.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain NAD_binding_11 PF14833.6 KFX99300.1 - 0.19 12.0 0.0 0.65 10.2 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MFS_1 PF07690.16 KFX99301.1 - 1.3e-33 116.4 21.4 1.3e-33 116.4 21.4 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily NACHT PF05729.12 KFX99301.1 - 9.8e-06 25.6 0.1 1.8e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 KFX99301.1 - 0.00032 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KFX99301.1 - 0.0012 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFX99301.1 - 0.0059 17.2 0.0 0.029 15.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KFX99301.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ANAPC4_WD40 PF12894.7 KFX99301.1 - 0.061 13.6 0.0 5.1 7.5 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 KFX99301.1 - 0.09 12.4 0.1 0.61 9.7 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX99301.1 - 0.2 10.9 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Fructosamin_kin PF03881.14 KFX99302.1 - 1.3e-31 109.9 0.0 1.8e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFX99302.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.22 KFX99303.1 - 2.3e-50 171.7 0.0 3.4e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KFX99303.1 - 4.1e-41 141.1 0.0 9.2e-15 54.7 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99303.1 - 1.6e-10 40.7 0.0 0.0021 17.4 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX99303.1 - 0.058 12.2 0.0 0.21 10.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF4025 PF13217.6 KFX99304.1 - 0.0058 16.5 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4025) Atx10homo_assoc PF09759.9 KFX99306.1 - 1.9e-14 53.5 0.0 6.1e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.29 KFX99306.1 - 2.5e-13 49.6 1.7 1.1e-08 34.7 0.2 3.6 3 0 0 3 3 3 2 KH domain Glyoxalase PF00903.25 KFX99307.1 - 6e-35 120.2 0.0 2.5e-16 60.0 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX99307.1 - 5.5e-13 49.1 0.0 8.1e-05 22.9 0.0 3.6 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFX99307.1 - 9.2e-10 39.3 0.0 0.00077 20.2 0.0 2.8 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFX99307.1 - 8.6e-06 26.0 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFX99307.1 - 0.0041 17.0 0.5 51 3.8 0.0 4.2 4 0 0 4 4 4 0 Glyoxalase-like domain MoaF PF10703.9 KFX99307.1 - 0.039 13.9 0.1 0.95 9.4 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain DUF1338 PF07063.13 KFX99307.1 - 0.082 12.1 0.0 10 5.2 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1338) GFA PF04828.14 KFX99309.1 - 5.5e-26 90.8 0.1 7.9e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acetyltransf_2 PF00797.17 KFX99310.1 - 4.6e-42 144.5 0.0 6.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase DUF2434 PF10361.9 KFX99312.1 - 2.1e-122 407.8 0.6 2.5e-122 407.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF1876 PF08962.11 KFX99320.1 - 0.0047 16.9 1.3 0.0073 16.3 1.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1876) Pectate_lyase_3 PF12708.7 KFX99327.1 - 1e-94 316.4 19.0 6.7e-77 258.2 7.2 3.6 3 0 0 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX99327.1 - 2.4e-06 27.1 3.1 0.047 13.4 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PAN_3 PF08277.12 KFX99327.1 - 9.2e-06 25.4 24.8 0.18 11.7 0.8 5.0 4 0 0 4 4 4 4 PAN-like domain Amidase PF01425.21 KFX99340.1 - 4e-40 138.1 0.1 2e-39 135.8 0.1 2.0 1 1 0 1 1 1 1 Amidase ADH_N PF08240.12 KFX99341.1 - 5.1e-17 61.7 0.7 1e-16 60.8 0.7 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX99341.1 - 2.7e-08 33.8 0.0 2.1e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFX99341.1 - 0.0011 18.9 1.3 0.0024 17.7 1.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KFX99341.1 - 0.025 13.9 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S28 PF05577.12 KFX99342.1 - 2.8e-52 178.0 1.0 8.8e-39 133.5 0.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KFX99342.1 - 0.15 11.6 0.0 22 4.5 0.0 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family adh_short PF00106.25 KFX99343.1 - 1.5e-23 83.3 0.0 4e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99343.1 - 3.8e-14 52.8 0.0 1.9e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99343.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX99343.1 - 0.027 13.9 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX99343.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SWI-SNF_Ssr4 PF08549.10 KFX99343.1 - 0.28 9.8 0.9 0.63 8.6 0.1 1.7 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Aldo_ket_red PF00248.21 KFX99344.1 - 1.1e-64 218.4 0.0 1.6e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KFX99361.1 - 2.6e-09 37.5 5.1 7e-07 29.8 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 KFX99361.1 - 0.0067 15.1 0.3 0.11 11.1 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFX99361.1 - 0.012 15.8 0.0 3.6 7.9 0.0 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_A_exo1 PF01612.20 KFX99362.1 - 1e-12 48.1 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease RE_BstXI PF09552.10 KFX99362.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 BstXI restriction endonuclease LSM PF01423.22 KFX99363.1 - 4.3e-20 71.2 0.2 6.8e-20 70.5 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFX99363.1 - 0.039 14.1 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Swm2 PF17083.5 KFX99363.1 - 0.071 13.1 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 Nucleolar protein Swm2 RNA_pol_L_2 PF13656.6 KFX99364.1 - 2.5e-24 84.8 0.0 3.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFX99364.1 - 4.8e-09 35.5 0.1 6.8e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Amidase PF01425.21 KFX99369.1 - 6.1e-30 104.6 0.0 9.7e-30 103.9 0.0 1.3 1 1 0 1 1 1 1 Amidase RAC_head PF16717.5 KFX99370.1 - 1.8e-32 112.2 2.6 1.8e-32 112.2 2.6 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KFX99370.1 - 6.4e-19 67.9 1.1 2.6e-18 65.9 1.1 2.2 1 0 0 1 1 1 1 DnaJ domain PspB PF06667.12 KFX99370.1 - 0.094 12.8 1.0 0.28 11.2 1.0 1.8 1 0 0 1 1 1 0 Phage shock protein B V_ATPase_I PF01496.19 KFX99370.1 - 0.46 8.3 9.2 0.73 7.7 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Complex1_LYR PF05347.15 KFX99371.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ORC6 PF05460.13 KFX99378.1 - 6.5 5.9 8.4 7.5 5.7 8.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Lipase_GDSL_2 PF13472.6 KFX99379.1 - 4.7e-08 33.6 0.9 9.6e-08 32.6 0.9 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX99379.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Myb_DNA-bind_4 PF13837.6 KFX99380.1 - 0.011 16.1 0.5 0.03 14.7 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Methyltransf_34 PF11312.8 KFX99381.1 - 7.9e-51 173.1 0.0 9.4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase adh_short PF00106.25 KFX99382.1 - 2.1e-32 112.2 0.0 2.6e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99382.1 - 8.9e-18 64.7 0.0 1.1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFX99382.1 - 1.4e-07 31.5 0.0 2.4e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX99382.1 - 2.8e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFX99382.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Crystall_3 PF08964.10 KFX99383.1 - 4.2e-09 36.5 0.2 5.9e-09 36.0 0.2 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 KFX99383.1 - 0.11 12.4 5.6 0.26 11.3 3.3 2.4 1 1 2 3 3 3 0 Peptidase inhibitor family I36 Alpha_L_fucos PF01120.17 KFX99384.1 - 7.5e-29 101.3 0.0 1e-27 97.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-L-fucosidase Nop16 PF09420.10 KFX99385.1 - 2.4e-69 233.6 12.3 2.7e-69 233.4 12.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 NDUF_B4 PF07225.12 KFX99386.1 - 0.013 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) adh_short PF00106.25 KFX99393.1 - 9.4e-20 70.9 0.3 3.5e-18 65.8 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99393.1 - 4.5e-13 49.3 0.4 2.2e-12 47.0 0.2 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99393.1 - 3.4e-06 27.1 0.4 6.5e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KFX99394.1 - 0.038 13.0 0.1 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 KFX99397.1 - 2.9e-40 137.8 0.4 3.6e-40 137.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99397.1 - 1e-31 110.3 0.0 1.4e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99397.1 - 3.8e-08 33.4 0.2 6.1e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX99397.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX99397.1 - 3e-05 23.6 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFX99397.1 - 3.5e-05 23.3 0.0 0.00034 20.1 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KFX99397.1 - 0.0035 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFX99397.1 - 0.01 15.0 0.1 0.018 14.2 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain PAE PF03283.13 KFX99397.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase DFP PF04127.15 KFX99397.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 KFX99398.1 - 3.4e-24 85.5 24.1 3.4e-24 85.5 24.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX99398.1 - 7.8e-08 31.6 36.5 5.9e-06 25.4 36.5 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF5336 PF17270.2 KFX99398.1 - 0.8 9.3 7.4 7.4 6.2 0.1 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5336) zf-C2H2 PF00096.26 KFX99399.1 - 0.012 16.0 0.8 0.012 16.0 0.8 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX99399.1 - 0.053 14.4 0.5 0.053 14.4 0.5 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger DUF4776 PF16003.5 KFX99399.1 - 0.15 11.1 7.4 0.096 11.7 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) GAGA PF09237.11 KFX99399.1 - 0.16 11.8 0.8 0.64 9.9 0.8 2.0 1 0 0 1 1 1 0 GAGA factor zf-C2H2_aberr PF17017.5 KFX99399.1 - 0.2 11.8 7.8 0.22 11.7 0.5 3.1 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KFX99399.1 - 0.69 10.3 16.6 0.4 11.0 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_65N PF03636.15 KFX99408.1 - 2.3e-31 109.2 0.0 4.8e-31 108.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KFX99408.1 - 1.2e-27 96.8 7.7 1.9e-24 86.2 2.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 KFX99408.1 - 0.0033 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 KFX99408.1 - 0.1 12.7 2.2 0.33 11.1 0.1 3.0 3 0 0 3 3 3 0 F5/8 type C domain SpoU_methylase PF00588.19 KFX99409.1 - 4.5e-25 88.5 0.0 8.8e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KFX99409.1 - 1e-08 35.3 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 KFX99410.1 - 5e-70 234.5 7.1 1.1e-69 233.3 7.1 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KFX99410.1 - 6.4e-54 183.0 0.0 1.2e-53 182.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 KFX99410.1 - 6.2e-25 86.8 0.1 1.6e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 KFX99410.1 - 1.3e-17 64.2 0.0 3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX99410.1 - 5e-12 45.6 0.6 1.4e-11 44.1 0.6 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KFX99410.1 - 1.5e-06 28.0 2.1 0.0011 18.8 0.7 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFX99410.1 - 2.7e-06 27.5 0.0 5.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KFX99410.1 - 8.4e-06 25.6 3.0 8.4e-06 25.6 3.0 3.5 2 1 1 3 3 3 1 PHD-finger DEAD PF00270.29 KFX99410.1 - 0.00046 20.0 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1087 PF06465.13 KFX99410.1 - 0.0028 17.6 0.0 0.0076 16.3 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) SnAC PF14619.6 KFX99410.1 - 0.036 14.7 0.2 0.18 12.4 0.2 2.3 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex PHD_2 PF13831.6 KFX99410.1 - 0.16 11.5 11.2 0.013 15.0 4.9 2.5 2 1 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 KFX99410.1 - 0.26 11.4 4.8 14 5.9 0.0 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 KFX99410.1 - 1.4 9.1 6.6 0.48 10.6 2.4 2.6 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KFX99410.1 - 1.4 8.9 9.8 0.27 11.1 1.7 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ PF00226.31 KFX99416.1 - 6.9e-10 38.9 1.2 3e-09 36.9 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain PRA1 PF03208.19 KFX99418.1 - 3.4e-37 127.2 0.8 4.1e-37 127.0 0.8 1.1 1 0 0 1 1 1 1 PRA1 family protein IMUP PF15761.5 KFX99419.1 - 0.0065 17.2 9.5 0.0065 17.2 9.5 3.1 2 1 1 3 3 3 1 Immortalisation up-regulated protein BRE1 PF08647.11 KFX99419.1 - 0.29 11.2 6.2 0.44 10.7 6.2 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase SOBP PF15279.6 KFX99419.1 - 1.4 9.5 15.8 1.8 9.1 15.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GREB1 PF15782.5 KFX99419.1 - 4.4 4.3 8.2 5.1 4.1 8.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer adh_short PF00106.25 KFX99437.1 - 2.5e-20 72.7 0.0 5.8e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99437.1 - 2.2e-13 50.3 0.0 6.3e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99437.1 - 2.6e-07 30.7 0.0 5.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 KR domain But2 PF09792.9 KFX99438.1 - 4e-09 37.0 0.5 5.5e-09 36.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.25 KFX99439.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family adh_short PF00106.25 KFX99440.1 - 4.6e-39 133.9 0.0 6.2e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99440.1 - 3.1e-28 98.9 0.0 4.3e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFX99440.1 - 1.3e-05 24.7 0.0 8.3e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFX99440.1 - 0.0075 15.8 0.0 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX99440.1 - 0.0093 15.5 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 KFX99440.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PRAI PF00697.22 KFX99440.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Zn_clus PF00172.18 KFX99441.1 - 2.4e-05 24.3 3.1 6e-05 23.1 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX99441.1 - 0.0064 15.3 1.0 0.012 14.5 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SYCP2_ARLD PF18581.1 KFX99441.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain Abhydrolase_1 PF00561.20 KFX99442.1 - 1e-18 67.9 0.1 1.2e-18 67.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX99442.1 - 1.4e-10 42.2 1.1 1.8e-10 41.8 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX99442.1 - 2.8e-08 33.3 0.0 1.6e-07 30.8 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFX99442.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase EHN PF06441.12 KFX99442.1 - 0.3 11.5 1.1 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Tannase PF07519.11 KFX99443.1 - 6.5e-101 338.5 0.0 7.6e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KFX99443.1 - 6.6e-05 22.3 0.0 0.00089 18.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX99443.1 - 0.00084 18.9 0.0 0.01 15.3 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFX99443.1 - 0.052 13.2 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Tubulin PF00091.25 KFX99445.1 - 3.4e-62 210.2 0.0 4.5e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX99445.1 - 3e-33 114.6 0.0 4.8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.25 KFX99445.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Tubulin_2 PF13809.6 KFX99445.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DUF3591 PF12157.8 KFX99448.1 - 3.1e-184 612.8 1.5 3.9e-184 612.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KFX99448.1 - 0.012 15.7 0.9 0.02 14.9 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFX99448.1 - 0.02 14.7 2.4 0.048 13.5 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle WSC PF01822.19 KFX99452.1 - 3.6e-08 33.5 4.9 3.6e-08 33.5 4.9 1.6 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KFX99452.1 - 1.4e-07 30.7 1.6 2.7e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KFX99452.1 - 0.00026 20.8 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Alpha_GJ PF03229.13 KFX99452.1 - 0.018 15.6 3.4 0.029 14.9 3.4 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Podoplanin PF05808.11 KFX99452.1 - 0.02 15.0 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Podoplanin DUF2207 PF09972.9 KFX99452.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_2_4 PF16082.5 KFX99452.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2263 PF10021.9 KFX99465.1 - 7.5e-16 58.8 0.0 1.1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.18 KFX99466.1 - 3.4e-10 39.4 0.8 7.3e-10 38.3 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX99467.1 - 4.8e-22 78.4 50.9 8.1e-17 61.2 19.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX99467.1 - 0.00023 20.1 9.0 0.00023 20.1 9.0 2.5 1 1 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.24 KFX99467.1 - 0.18 10.7 31.7 0.61 8.9 6.4 3.5 1 1 1 3 3 3 0 Sugar (and other) transporter Trp_oprn_chp PF09534.10 KFX99467.1 - 0.47 10.2 4.4 29 4.4 0.0 3.4 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RAP1 PF07218.11 KFX99468.1 - 0.16 10.2 11.5 0.2 9.9 11.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sugar_tr PF00083.24 KFX99469.1 - 1.6e-56 192.1 26.3 1.9e-56 191.8 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99469.1 - 5.4e-22 78.2 26.7 7.6e-22 77.7 26.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 KFX99470.1 - 1e-62 212.1 0.0 1.4e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 KFX99471.1 - 1.3e-143 478.8 0.4 2.3e-143 477.9 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cupin_1 PF00190.22 KFX99471.1 - 3.4e-11 43.0 0.2 2.6e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 Cupin Cupin_2 PF07883.11 KFX99471.1 - 0.00033 20.3 0.1 0.00072 19.2 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Sulfatase PF00884.23 KFX99472.1 - 3.1e-15 56.4 0.1 7e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFX99472.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.18 KFX99472.1 - 0.0054 16.8 18.9 0.0088 16.1 18.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX99473.1 - 1.8e-13 50.2 0.2 4.3e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99473.1 - 6.3e-06 26.2 12.4 1.4e-05 25.1 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX99474.1 - 1e-15 57.5 30.8 1.1e-13 50.9 10.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily AidB_N PF18158.1 KFX99475.1 - 1.2e-17 64.2 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX99475.1 - 1.2e-16 61.3 0.0 3.3e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX99475.1 - 5.2e-11 42.6 0.0 1.6e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3750 PF12570.8 KFX99475.1 - 0.13 12.9 1.0 0.36 11.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) AMP-binding PF00501.28 KFX99476.1 - 2.1e-44 151.8 0.0 2.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX99476.1 - 0.00053 20.9 0.0 0.0012 19.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 KFX99477.1 - 5.8e-59 196.0 0.6 1.8e-19 69.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl-CoA_dh_N PF02771.16 KFX99478.1 - 2.1e-26 92.8 0.1 3.8e-26 92.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX99478.1 - 7.6e-25 87.9 0.1 1.2e-24 87.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX99478.1 - 4.4e-18 65.3 0.0 8.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX99478.1 - 2.4e-07 31.1 0.1 4.1e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MARVEL PF01284.23 KFX99479.1 - 1.5e-14 54.2 15.5 2.4e-14 53.6 15.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4094 PF13334.6 KFX99479.1 - 0.19 12.1 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) ABC2_membrane_5 PF13346.6 KFX99479.1 - 0.21 11.1 12.0 0.72 9.4 12.2 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein YMF19 PF02326.15 KFX99479.1 - 0.32 11.8 0.0 0.32 11.8 0.0 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 PI3Ka PF00613.20 KFX99495.1 - 4.4e-58 195.7 0.3 7e-58 195.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFX99495.1 - 4.5e-43 147.9 0.0 7.5e-28 98.0 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KFX99495.1 - 1.1e-32 112.9 0.0 2e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PAM2 PF07145.15 KFX99503.1 - 0.088 12.5 1.2 0.24 11.2 0.1 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Baculo_PEP_C PF04513.12 KFX99504.1 - 0.001 19.1 10.4 1.7 8.7 0.1 4.3 2 2 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF599 PF04654.12 KFX99504.1 - 0.0015 18.0 0.3 0.005 16.3 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF4199 PF13858.6 KFX99504.1 - 0.056 13.8 0.2 0.056 13.8 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) DUF4231 PF14015.6 KFX99504.1 - 1.5 9.4 6.1 49 4.5 0.1 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF4231) DUF1741 PF08427.10 KFX99505.1 - 1.7e-50 171.8 0.0 3.2e-50 171.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) Fungal_trans PF04082.18 KFX99508.1 - 3.6e-23 81.9 0.0 9.1e-23 80.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99508.1 - 0.008 16.3 4.6 0.013 15.6 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps5 PF09325.10 KFX99508.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like CCDC53 PF10152.9 KFX99508.1 - 0.069 13.6 0.3 0.12 12.8 0.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex VWA PF00092.28 KFX99525.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA PF00004.29 KFX99539.1 - 3.5e-17 63.1 0.0 7.2e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFX99539.1 - 2e-12 47.2 0.0 1.8e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KFX99539.1 - 3.4e-10 40.2 0.0 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KFX99539.1 - 1.5e-09 38.0 0.0 3e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KFX99539.1 - 2e-07 30.9 0.3 6.6e-07 29.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFX99539.1 - 2.1e-06 27.7 0.2 0.00014 21.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX99539.1 - 2.7e-06 27.9 0.0 2e-05 25.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KFX99539.1 - 2.8e-06 27.6 0.1 9e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_24 PF13479.6 KFX99539.1 - 3.8e-06 26.8 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFX99539.1 - 9.2e-06 26.0 0.0 3.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFX99539.1 - 1e-05 25.5 0.4 3.8e-05 23.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KFX99539.1 - 2.3e-05 24.2 0.1 5.6e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KFX99539.1 - 2.4e-05 23.7 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX99539.1 - 2.5e-05 24.1 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 KFX99539.1 - 4.6e-05 23.2 0.0 0.00018 21.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX99539.1 - 0.00033 20.5 0.1 0.0018 18.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KFX99539.1 - 0.00037 20.0 0.2 0.5 9.8 0.0 2.4 1 1 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 KFX99539.1 - 0.0006 19.9 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX99539.1 - 0.0011 19.4 2.3 0.0019 18.6 0.1 2.3 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFX99539.1 - 0.0014 18.0 0.1 0.012 15.0 0.1 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFX99539.1 - 0.008 16.2 0.0 0.12 12.3 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KFX99539.1 - 0.014 16.0 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX99539.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFX99539.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KFX99539.1 - 0.022 14.2 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 KFX99539.1 - 0.025 14.2 0.1 0.12 12.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KFX99539.1 - 0.026 14.3 0.1 0.21 11.3 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KFX99539.1 - 0.032 14.6 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KFX99539.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KFX99539.1 - 0.058 13.3 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KFX99539.1 - 0.1 12.3 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Flavi_DEAD PF07652.14 KFX99539.1 - 0.15 12.1 1.0 52 3.8 0.0 3.1 2 1 1 3 3 3 0 Flavivirus DEAD domain Metallopep PF12044.8 KFX99562.1 - 4.3e-166 552.8 0.0 5.5e-166 552.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KFX99562.1 - 0.027 14.4 0.0 0.32 10.9 0.0 2.5 2 1 0 2 2 2 0 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KFX99562.1 - 0.042 14.0 0.4 0.079 13.1 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Glyco_trans_2_3 PF13632.6 KFX99565.1 - 2.6e-52 177.6 1.3 2.6e-52 177.6 1.3 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFX99565.1 - 0.0022 17.8 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sec7 PF01369.20 KFX99566.1 - 2e-28 99.3 0.0 4.5e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFX99566.1 - 2.7e-20 72.9 0.0 5.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Herpes_LMP1 PF05297.11 KFX99566.1 - 3.6 6.7 5.2 8.6 5.4 5.2 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WH1 PF00568.23 KFX99573.1 - 8.5e-24 83.6 0.1 1.3e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 KFX99573.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family CorA PF01544.18 KFX99574.1 - 9.6e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 KFX99574.1 - 0.13 11.5 0.5 0.2 11.0 0.5 1.3 1 0 0 1 1 1 0 Apolipoprotein L DDE_Tnp_ISL3 PF01610.17 KFX99574.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Transposase ERCC4 PF02732.15 KFX99577.1 - 5.7e-19 68.8 0.0 1.2e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Dabb PF07876.12 KFX99578.1 - 1.1e-11 45.2 0.1 1.2e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4286 PF14114.6 KFX99578.1 - 0.033 14.7 0.2 5.1 7.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4286) Hydrolase_4 PF12146.8 KFX99580.1 - 0.076 12.3 0.0 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX99580.1 - 0.11 12.1 0.0 0.75 9.4 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold ArsA_ATPase PF02374.15 KFX99581.1 - 1.9e-113 378.7 0.0 2.2e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KFX99581.1 - 3.5e-13 49.9 0.1 6.1e-12 45.8 0.0 2.4 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KFX99581.1 - 2.3e-12 47.1 0.0 4.1e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KFX99581.1 - 2.3e-06 27.3 0.3 0.00029 20.4 0.0 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KFX99581.1 - 6e-06 25.9 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KFX99581.1 - 6.9e-05 22.6 0.2 0.0027 17.4 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KFX99581.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 KFX99581.1 - 0.0067 16.8 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFX99581.1 - 0.031 13.9 0.1 0.075 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX99581.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RecG_N PF17190.4 KFX99581.1 - 0.16 12.7 1.7 0.34 11.7 0.7 2.0 2 0 0 2 2 2 0 RecG N-terminal helical domain Transthyretin PF00576.21 KFX99582.1 - 1.6e-34 118.9 0.0 1.8e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family SIR2 PF02146.17 KFX99587.1 - 7.8e-29 100.8 0.0 2.6e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Sir2 family CNOT1_TTP_bind PF16417.5 KFX99587.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Med16 PF11635.8 KFX99588.1 - 7.6e-86 288.7 0.0 1e-85 288.3 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 KFX99588.1 - 0.018 15.3 0.0 0.34 11.2 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Anoctamin PF04547.12 KFX99589.1 - 0.18 10.6 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Defensin_like PF10868.8 KFX99595.1 - 3.6e-05 24.4 3.4 3.8 8.3 0.1 3.4 3 0 0 3 3 3 3 Cysteine-rich antifungal protein 2, defensin-like Macin PF14865.6 KFX99595.1 - 0.00032 21.2 0.8 4.1 8.0 0.0 3.1 3 0 0 3 3 3 2 Macin DnaT PF17948.1 KFX99595.1 - 0.011 15.4 0.4 26 4.6 0.0 3.1 3 0 0 3 3 3 0 DnaT DNA-binding domain Defensin_5 PF18251.1 KFX99595.1 - 0.072 13.2 6.6 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Fungal defensin Copsin zf-RAG1 PF10426.9 KFX99595.1 - 1.4 9.1 10.0 29 4.9 0.3 3.4 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain zf-UBP_var PF17807.1 KFX99595.1 - 9.9 6.0 6.8 74 3.2 0.2 3.1 3 0 0 3 3 3 0 Variant UBP zinc finger GFO_IDH_MocA PF01408.22 KFX99596.1 - 8.1e-25 88.0 0.0 1.5e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX99596.1 - 6.9e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX99596.1 - 0.00019 22.0 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KFX99596.1 - 0.0008 19.8 0.0 0.0021 18.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TB2_DP1_HVA22 PF03134.19 KFX99617.1 - 6.8e-20 70.8 8.9 9.7e-20 70.3 8.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family EAF PF09816.9 KFX99626.1 - 3.3e-17 62.7 0.0 4e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FAD_binding_7 PF03441.14 KFX99627.1 - 1e-38 132.9 0.0 1.6e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFX99627.1 - 8.4e-19 68.2 0.0 1.6e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase HTH_51 PF18558.1 KFX99638.1 - 1.7e-25 88.7 0.0 4.8e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 KFX99638.1 - 2.3e-24 85.5 3.9 1.4e-11 44.6 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KFX99638.1 - 2.4e-14 53.2 0.0 6.1e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Methyltransf_23 PF13489.6 KFX99638.1 - 1.9e-08 34.3 0.1 1.4e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX99638.1 - 1.3e-07 32.2 0.0 6.1e-07 30.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX99638.1 - 8.9e-07 29.6 0.1 7e-06 26.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99638.1 - 7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99638.1 - 1.5e-05 25.6 0.1 6.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.10 KFX99638.1 - 0.00045 20.2 0.1 0.0014 18.6 0.1 1.8 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX99638.1 - 0.0022 17.5 0.0 0.0058 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RrnaAD PF00398.20 KFX99638.1 - 0.0037 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase YjeF_N PF03853.15 KFX99638.1 - 0.0055 16.6 0.9 5.5 6.8 0.0 3.3 3 0 0 3 3 3 2 YjeF-related protein N-terminus AAA PF00004.29 KFX99639.1 - 1.8e-09 38.2 0.9 5.5e-08 33.3 0.9 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFX99639.1 - 1.9e-07 31.2 0.7 0.00037 20.5 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KFX99639.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX99639.1 - 0.005 17.1 0.0 0.016 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX99639.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFX99639.1 - 0.02 14.8 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 KFX99639.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFX99639.1 - 0.078 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX99639.1 - 0.099 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KFX99639.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX99639.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KFX99639.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFX99639.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFX99639.1 - 6.6 7.2 9.3 5.8 7.4 5.2 2.7 1 1 1 2 2 2 0 AAA domain Utp8 PF10395.9 KFX99640.1 - 5e-18 65.0 0.5 1.9e-13 49.9 0.1 3.4 2 1 0 2 2 2 2 Utp8 family Helo_like_N PF17111.5 KFX99641.1 - 1.7e-05 24.3 0.2 3.2e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KFX99641.1 - 0.011 16.0 0.0 0.037 14.2 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DNA_binding_1 PF01035.20 KFX99642.1 - 3.1e-25 88.1 0.0 3.7e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 KFX99643.1 - 1.4e-30 105.1 3.7 2.3e-30 104.4 3.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KFX99643.1 - 1.1e-07 31.8 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KFX99643.1 - 0.0006 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-synt_F PF01990.17 KFX99660.1 - 1.2e-33 115.3 0.1 1.4e-33 115.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit AMP-binding_C PF13193.6 KFX99660.1 - 0.14 13.2 0.3 0.4 11.7 0.3 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain E1_DerP2_DerF2 PF02221.15 KFX99661.1 - 9.1e-27 94.1 0.2 1.1e-26 93.9 0.2 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 KFX99661.1 - 0.0095 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) NPCBM_assoc PF10633.9 KFX99661.1 - 0.072 13.3 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Arf PF00025.21 KFX99666.1 - 3.3e-44 150.4 0.0 3.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFX99666.1 - 1.5e-18 67.0 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX99666.1 - 5.6e-16 58.9 0.0 7.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX99666.1 - 3.9e-08 32.9 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFX99666.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX99666.1 - 9.6e-06 25.1 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFX99666.1 - 0.0003 20.1 0.3 0.0016 17.7 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KFX99666.1 - 0.011 15.2 0.2 0.038 13.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX99666.1 - 0.065 13.3 0.0 0.37 10.8 0.1 1.9 1 1 1 2 2 2 0 Dynamin family NACHT PF05729.12 KFX99666.1 - 0.11 12.4 0.4 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KFX99666.1 - 0.14 11.9 0.1 2.1 8.1 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KFX99666.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RCR PF12273.8 KFX99667.1 - 3.2e-22 79.4 7.7 4.4e-22 79.0 7.7 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.18 KFX99667.1 - 0.3 9.5 0.8 0.39 9.1 0.8 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Corona_S2 PF01601.16 KFX99668.1 - 0.049 12.1 18.4 0.068 11.7 18.4 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Podoplanin PF05808.11 KFX99669.1 - 0.013 15.6 0.2 0.029 14.5 0.2 1.6 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 KFX99669.1 - 0.066 12.1 0.4 0.1 11.4 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glycophorin_A PF01102.18 KFX99669.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Glyco_hydro_43 PF04616.14 KFX99677.1 - 2.2e-10 40.3 1.4 3.6e-10 39.6 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RTC4 PF14474.6 KFX99678.1 - 2.1e-30 105.3 0.0 3.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain zf-Mss51 PF13824.6 KFX99678.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADIP PF11559.8 KFX99681.1 - 1.7e-33 115.8 0.6 1.9e-33 115.7 0.6 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 KFX99681.1 - 0.029 14.4 1.0 0.029 14.4 1.0 1.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ferric_reduct PF01794.19 KFX99683.1 - 2.8e-17 63.0 10.9 2.8e-17 63.0 10.9 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX99683.1 - 9.9e-15 54.6 0.0 2.6e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX99683.1 - 1.8e-06 28.2 3.5 5.3e-06 26.6 3.5 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain IGPD PF00475.18 KFX99692.1 - 1.5e-59 200.4 0.2 2.4e-59 199.8 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.11 KFX99694.1 - 1.8e-23 82.7 0.1 7.2e-23 80.8 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KFX99694.1 - 3.3e-12 46.5 0.0 2.9e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFX99694.1 - 2.5e-11 44.1 0.0 4.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFX99694.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX99694.1 - 9.6e-06 26.1 0.1 0.00094 19.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX99694.1 - 3.2e-05 24.2 0.1 0.079 13.2 0.0 2.7 2 1 1 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 KFX99694.1 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KFX99694.1 - 0.0004 20.2 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX99694.1 - 0.00049 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFX99694.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFX99694.1 - 0.0024 17.3 0.1 0.034 13.5 0.1 2.5 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFX99694.1 - 0.0048 16.3 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 KFX99694.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KFX99694.1 - 0.0094 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX99694.1 - 0.011 16.1 0.2 0.049 14.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KFX99694.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.29 KFX99694.1 - 0.025 14.4 0.1 0.68 9.7 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 KFX99694.1 - 0.026 14.4 0.1 0.12 12.2 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_30 PF13604.6 KFX99694.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KFX99694.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_24 PF13479.6 KFX99694.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFX99694.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFX99694.1 - 0.11 12.9 0.0 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFX99694.1 - 0.17 11.5 0.0 0.6 9.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Asp PF00026.23 KFX99695.1 - 8.5e-73 245.5 1.6 1e-72 245.2 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX99695.1 - 1.9e-14 54.3 1.1 1.1e-11 45.3 1.0 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX99695.1 - 0.0061 17.2 0.1 6.3 7.5 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KFX99695.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF834 PF05754.14 KFX99695.1 - 0.13 12.3 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF834) AAA PF00004.29 KFX99696.1 - 4.8e-19 69.1 0.0 1.1e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX99696.1 - 0.0016 18.7 0.4 0.029 14.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX99696.1 - 0.0026 18.2 0.7 0.0062 16.9 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KFX99696.1 - 0.0028 17.8 0.1 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFX99696.1 - 0.028 14.4 0.1 0.084 12.9 0.1 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFX99696.1 - 0.042 14.4 0.1 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KFX99696.1 - 0.2 11.0 0.2 0.61 9.4 0.1 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DAO PF01266.24 KFX99697.1 - 3.5e-28 99.2 0.0 4.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX99697.1 - 6.8e-05 23.0 0.1 0.0002 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX99697.1 - 0.0013 18.0 0.0 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX99697.1 - 0.0024 17.9 0.0 0.088 12.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFX99697.1 - 0.019 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KFX99697.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 KFX99697.1 - 0.04 13.0 0.1 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KFX99697.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family PPTA PF01239.22 KFX99697.1 - 0.11 12.3 2.1 0.25 11.1 1.3 2.1 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat FAD_binding_2 PF00890.24 KFX99697.1 - 0.17 10.9 0.1 0.41 9.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KFX99697.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KFX99698.1 - 7.4e-63 213.0 22.7 1.1e-62 212.4 22.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 KFX99698.1 - 3e-27 95.3 0.5 5.7e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX99698.1 - 2.8e-20 72.6 37.3 2.2e-18 66.3 19.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KFX99698.1 - 1.8e-09 37.5 7.5 3.8e-09 36.5 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 KFX99698.1 - 0.017 15.1 0.5 0.068 13.1 0.5 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension LysM PF01476.20 KFX99699.1 - 6e-11 42.2 0.2 0.00012 22.0 0.1 3.1 3 0 0 3 3 3 2 LysM domain Mfa_like_2 PF15415.6 KFX99699.1 - 0.013 14.4 0.2 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 Fimbrillin-like MafB PF06255.13 KFX99699.1 - 0.15 11.5 0.2 18 4.7 0.0 2.5 2 1 1 3 3 3 0 Neisseria toxin MafB Chitin_bind_1 PF00187.19 KFX99699.1 - 0.32 11.5 27.2 0.069 13.6 20.5 3.1 3 0 0 3 3 3 0 Chitin recognition protein SPDY PF03771.16 KFX99700.1 - 0.14 12.2 1.4 0.41 10.6 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Ifi-6-16 PF06140.13 KFX99702.1 - 2.8e-11 43.2 38.0 6.3e-08 32.4 17.9 2.7 2 1 0 2 2 2 2 Interferon-induced 6-16 family TcdA_TcdB_pore PF12920.7 KFX99702.1 - 0.13 10.5 2.6 0.22 9.7 2.6 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Phage_holin_3_1 PF05106.12 KFX99702.1 - 2.2 8.7 7.1 4.7 7.7 1.6 2.5 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) UQ_con PF00179.26 KFX99703.1 - 4.6e-37 126.8 0.0 9.8e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cut12 PF11500.8 KFX99703.1 - 3.9e-36 124.2 11.7 3.9e-36 124.2 11.7 3.7 2 2 1 3 3 3 1 Spindle pole body formation-associated protein CorA PF01544.18 KFX99703.1 - 3.9 6.7 12.9 0.15 11.3 2.5 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein TMF_TATA_bd PF12325.8 KFX99703.1 - 4.2 7.6 27.1 2 8.7 17.1 3.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cir_Bir_Yir PF06022.11 KFX99703.1 - 8.4 5.8 8.4 0.21 11.1 1.6 1.7 2 0 0 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir DUF1640 PF07798.11 KFX99703.1 - 8.8 6.3 21.7 49 3.9 21.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 KFX99703.1 - 10 6.4 23.8 2.4 8.4 3.3 4.2 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LRR_6 PF13516.6 KFX99704.1 - 0.011 15.7 0.0 43 4.5 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat Histone PF00125.24 KFX99705.1 - 6e-41 139.9 0.5 7.2e-41 139.6 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFX99705.1 - 1.5e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KFX99705.1 - 5.4e-05 23.3 0.0 8.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFX99705.1 - 0.0065 16.7 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DER1 PF04511.15 KFX99706.1 - 4.5e-54 183.3 6.1 5.2e-54 183.1 6.1 1.0 1 0 0 1 1 1 1 Der1-like family PNRC PF15365.6 KFX99707.1 - 1.2e-08 34.6 8.7 1.2e-08 34.6 8.7 5.6 6 0 0 6 6 6 2 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KFX99708.1 - 3.7e-25 88.0 13.1 4.9e-25 87.6 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFX99708.1 - 4.5e-17 61.9 10.0 6e-17 61.5 10.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFX99708.1 - 3.1e-06 27.4 14.6 0.0001 22.6 14.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX99708.1 - 8.2e-05 22.4 3.4 8.2e-05 22.4 3.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX99708.1 - 0.0018 18.1 11.8 0.029 14.3 11.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX99708.1 - 0.2 11.5 10.7 0.54 10.2 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX99708.1 - 0.53 10.1 16.2 40 4.1 16.2 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFX99708.1 - 0.56 10.3 7.7 1.9 8.6 7.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KFX99708.1 - 0.66 10.2 9.3 3.3 8.0 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFX99708.1 - 0.77 9.4 14.9 0.14 11.8 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type SPC12 PF06645.13 KFX99709.1 - 1.8e-29 101.6 0.5 2.2e-29 101.4 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KFX99709.1 - 0.026 14.8 3.9 0.041 14.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MerC PF03203.14 KFX99709.1 - 0.033 14.7 0.3 0.033 14.6 0.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3379 PF11859.8 KFX99709.1 - 0.17 11.1 0.3 0.22 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) MS_channel PF00924.18 KFX99709.1 - 0.7 9.4 4.6 1.2 8.6 4.6 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel CorA PF01544.18 KFX99710.1 - 1.4e-43 149.3 0.2 2.3e-43 148.6 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein T6_Ig_like PF18002.1 KFX99710.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 T6 antigen Ig like domain zf-Tim10_DDP PF02953.15 KFX99711.1 - 6.3e-24 83.4 1.5 8.4e-24 83.0 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF228 PF02989.14 KFX99711.1 - 0.074 12.9 0.4 0.089 12.6 0.4 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function YkuI_C PF10388.9 KFX99711.1 - 0.081 12.7 0.2 0.084 12.7 0.2 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Ribosomal_L23eN PF03939.13 KFX99712.1 - 5.1e-28 97.0 7.3 1.1e-27 96.0 7.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFX99712.1 - 2e-15 56.9 1.0 2e-15 56.9 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 Bmt2 PF11968.8 KFX99713.1 - 1.8e-87 292.8 0.0 2.2e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 EF-hand_8 PF13833.6 KFX99713.1 - 0.075 12.9 0.1 4 7.4 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain pair Methyltransf_23 PF13489.6 KFX99713.1 - 0.091 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aa_trans PF01490.18 KFX99714.1 - 2.5e-61 207.6 25.8 3e-61 207.3 25.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.15 KFX99715.1 - 4.2e-47 159.8 0.1 7.7e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFX99715.1 - 1.2e-39 135.2 0.9 2.5e-39 134.2 0.9 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFX99715.1 - 1.2e-21 77.0 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KFX99715.1 - 2e-10 41.0 0.0 4.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KFX99715.1 - 1.2e-08 35.3 0.1 1.9e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 KFX99715.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PDT PF00800.18 KFX99716.1 - 2.1e-59 200.4 0.0 6.5e-59 198.8 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydratase MaoC_dehydratas PF01575.19 KFX99716.1 - 3.1e-05 23.5 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain ACT PF01842.25 KFX99716.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain RNA_pol_3_Rpc31 PF11705.8 KFX99726.1 - 0.1 12.9 14.0 0.11 12.7 14.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF5401 PF17380.2 KFX99726.1 - 0.13 10.4 22.8 0.15 10.1 22.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AAA_11 PF13086.6 KFX99726.1 - 0.14 11.9 14.8 0.17 11.6 14.8 1.0 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KFX99726.1 - 0.34 10.2 8.8 0.36 10.1 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAP1 PF07218.11 KFX99726.1 - 0.44 8.8 11.9 0.49 8.6 11.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FapA PF03961.13 KFX99726.1 - 0.96 8.0 14.2 1.1 7.7 14.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF853 PF05872.12 KFX99726.1 - 1.7 7.2 5.7 1.8 7.1 5.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folate_carrier PF01770.18 KFX99726.1 - 2.8 6.6 5.1 2.8 6.6 5.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2207 PF09972.9 KFX99726.1 - 3.4 6.3 10.0 3.5 6.3 10.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec62 PF03839.16 KFX99726.1 - 4.8 6.6 15.4 5.2 6.5 15.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Borrelia_P83 PF05262.11 KFX99726.1 - 5.7 5.3 20.0 6.4 5.2 20.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.16 KFX99726.1 - 8.5 5.2 6.9 8.6 5.1 6.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 KFX99726.1 - 9.9 5.1 9.0 11 4.9 9.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Self-incomp_S1 PF05938.11 KFX99728.1 - 0.029 14.9 1.7 0.044 14.3 1.7 1.3 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 DUF3844 PF12955.7 KFX99728.1 - 0.32 11.1 3.1 0.57 10.4 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Ndc1_Nup PF09531.10 KFX99729.1 - 1.5 7.4 5.2 1.6 7.3 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 KFX99729.1 - 2.3 6.8 13.1 3.2 6.3 13.1 1.2 1 0 0 1 1 1 0 Hamartin protein DUF2207 PF09972.9 KFX99730.1 - 0.19 10.5 1.3 0.22 10.3 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sid-5 PF17204.3 KFX99730.1 - 0.52 10.5 3.0 0.78 9.9 1.7 1.9 3 0 0 3 3 3 0 Sid-5 family CDC45 PF02724.14 KFX99731.1 - 9.7 4.3 10.0 10 4.3 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cation_efflux PF01545.21 KFX99733.1 - 5.4e-06 26.3 2.7 5.4e-06 26.3 2.7 2.1 2 0 0 2 2 2 2 Cation efflux family Cation_efflux PF01545.21 KFX99734.1 - 8.3e-32 110.5 5.0 9.6e-32 110.3 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2776 PF10951.8 KFX99734.1 - 0.0089 15.3 0.2 0.0089 15.3 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2776) TM140 PF14985.6 KFX99734.1 - 0.012 15.1 0.3 0.02 14.4 0.3 1.5 1 0 0 1 1 1 0 TM140 protein family DUF3483 PF11982.8 KFX99734.1 - 0.017 14.8 1.1 0.023 14.3 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) Phage_holin_5_2 PF16079.5 KFX99734.1 - 0.038 14.3 0.6 0.91 9.9 0.0 2.6 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V RINGv PF12906.7 KFX99744.1 - 5.8e-09 35.9 3.7 1.2e-08 34.9 0.8 2.3 2 0 0 2 2 2 1 RING-variant domain Xan_ur_permease PF00860.20 KFX99744.1 - 0.11 11.2 0.2 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 Permease family zf-RING_2 PF13639.6 KFX99744.1 - 0.28 11.6 5.1 1.1 9.6 1.5 2.2 2 0 0 2 2 2 0 Ring finger domain Proteasome PF00227.26 KFX99745.1 - 3.6e-57 192.9 0.0 4.5e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFX99745.1 - 2e-10 40.1 0.4 5.1e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature 3HCDH_N PF02737.18 KFX99749.1 - 6e-31 107.7 0.0 8.6e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFX99749.1 - 3.6e-17 62.8 0.0 6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFX99749.1 - 0.0061 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KFX99749.1 - 0.02 14.6 0.0 0.1 12.2 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFX99749.1 - 0.056 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KFX99749.1 - 0.18 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 KFX99750.1 - 3.4e-31 108.1 0.0 6.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFX99750.1 - 1.5e-30 105.5 0.0 2.5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KFX99750.1 - 1.2e-21 76.6 0.0 2.3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFX99750.1 - 0.002 18.3 0.0 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain p450 PF00067.22 KFX99751.1 - 1.7e-58 198.5 0.0 2.1e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 KFX99752.1 - 9e-29 100.0 0.8 1.5e-28 99.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX99752.1 - 2.4e-10 40.4 0.0 5.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HK PF02110.15 KFX99753.1 - 5.6e-75 251.9 0.3 7.9e-75 251.4 0.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KFX99753.1 - 5.5e-56 188.8 1.1 9.2e-56 188.0 1.1 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KFX99753.1 - 9e-07 28.6 0.4 3.7e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KFX99753.1 - 0.0056 16.1 0.8 0.13 11.6 0.1 2.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.6 KFX99753.1 - 0.011 15.4 0.3 0.44 10.2 0.0 3.1 2 1 2 4 4 4 0 Periplasmic binding protein POC3_POC4 PF10448.9 KFX99753.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 LPP20 PF02169.16 KFX99760.1 - 0.034 14.5 0.4 0.041 14.2 0.4 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein Sad1_UNC PF07738.13 KFX99762.1 - 7e-10 39.0 0.0 7.2e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal MreB_Mbl PF06723.13 KFX99776.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein ETF PF01012.21 KFX99777.1 - 3.3e-43 147.7 0.1 3.9e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Trp_ring PF18669.1 KFX99777.1 - 0.047 13.9 0.6 0.12 12.5 0.6 1.6 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Cyclin_N PF00134.23 KFX99778.1 - 7.2e-06 25.8 0.2 0.0017 18.1 0.1 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KFX99778.1 - 0.00034 20.6 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Reprolysin_5 PF13688.6 KFX99779.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 FSH1 PF03959.13 KFX99780.1 - 8.1e-31 107.3 0.0 1.8e-30 106.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFX99780.1 - 0.033 14.8 0.0 0.038 14.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec63 PF02889.16 KFX99782.1 - 1.8e-130 433.6 0.0 7.7e-77 257.9 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFX99782.1 - 4.9e-50 169.7 0.2 1.1e-25 90.4 0.3 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KFX99782.1 - 1.7e-20 73.7 0.0 2.5e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX99782.1 - 1.1e-15 57.9 0.0 1e-06 29.1 0.0 4.0 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFX99782.1 - 1.6e-07 31.2 0.1 0.013 15.3 0.5 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFX99782.1 - 1.6e-07 31.6 0.6 0.014 15.7 0.0 4.1 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KFX99782.1 - 1.8e-05 25.1 0.4 0.0057 17.0 0.6 2.9 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KFX99782.1 - 7.3e-05 22.9 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 KFX99782.1 - 0.00029 21.3 0.1 1.9 8.9 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFX99782.1 - 0.026 14.2 0.1 7.4 6.3 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KFX99782.1 - 0.072 12.1 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KFX99782.1 - 0.15 11.4 0.6 19 4.6 0.1 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 KFX99783.1 - 1.6e-13 50.2 0.5 3.2e-13 49.3 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KFX99783.1 - 2.9e-10 40.0 0.0 6.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain FMN_dh PF01070.18 KFX99784.1 - 2e-121 405.3 0.1 2.5e-121 405.0 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFX99784.1 - 7.5e-23 80.5 0.0 1.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFX99784.1 - 4.6e-09 35.9 0.1 8e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFX99784.1 - 0.0002 20.5 0.6 0.00053 19.1 0.4 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFX99784.1 - 0.014 14.8 0.7 0.032 13.6 0.2 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 KFX99784.1 - 0.034 13.5 1.2 0.86 8.9 0.1 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFX99784.1 - 0.1 12.0 0.8 2.4 7.6 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein HMGL-like PF00682.19 KFX99785.1 - 8.5e-80 268.1 0.2 1.2e-79 267.6 0.2 1.2 1 0 0 1 1 1 1 HMGL-like BRX_N PF13713.6 KFX99785.1 - 0.024 14.4 0.4 0.093 12.5 0.4 2.0 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Glyco_hydro_61 PF03443.14 KFX99786.1 - 4.5e-50 170.4 0.0 5.2e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cadherin_pro PF08758.11 KFX99786.1 - 0.0096 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Cadherin prodomain like DUF1751 PF08551.10 KFX99788.1 - 1.1e-22 80.5 4.1 1.7e-22 79.9 4.1 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KFX99788.1 - 0.011 15.7 2.4 0.019 14.9 2.4 1.3 1 0 0 1 1 1 0 Rhomboid family WD40 PF00400.32 KFX99789.1 - 5.8e-13 49.1 5.8 0.012 16.5 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99789.1 - 1.4e-12 47.8 0.0 0.0025 18.1 0.0 4.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KFX99789.1 - 4.3e-08 32.8 0.0 8.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.12 KFX99789.1 - 0.0015 18.4 3.7 4.5 7.3 0.0 4.3 4 1 1 5 5 5 2 WD40-like Beta Propeller Repeat Peptidase_M24 PF00557.24 KFX99790.1 - 1e-41 143.0 0.0 1.3e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KFX99790.1 - 0.19 11.7 2.1 0.37 10.8 2.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 BUD22 PF09073.10 KFX99790.1 - 0.81 9.0 11.6 1 8.6 11.6 1.1 1 0 0 1 1 1 0 BUD22 Stc1 PF12898.7 KFX99801.1 - 6.1e-18 65.1 12.5 1.1e-17 64.3 12.5 1.4 1 0 0 1 1 1 1 Stc1 domain His_Me_b4a2 PF18275.1 KFX99801.1 - 0.51 10.5 7.9 0.65 10.1 3.1 2.5 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain zf-CHY PF05495.12 KFX99801.1 - 1.6 9.2 10.6 0.37 11.3 5.6 2.1 1 1 1 2 2 2 0 CHY zinc finger zf-CCHC_2 PF13696.6 KFX99801.1 - 3.4 7.6 5.9 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle NYD-SP28_assoc PF14775.6 KFX99807.1 - 0.062 13.4 1.0 0.14 12.3 0.2 2.0 1 1 0 2 2 2 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 KFX99807.1 - 0.18 11.9 4.3 0.27 11.4 3.6 1.6 1 1 0 1 1 1 0 bZIP transcription factor DUF2417 PF10329.9 KFX99808.1 - 4.7e-37 127.7 0.0 6.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) HMG_box PF00505.19 KFX99809.1 - 1.5e-11 44.5 0.4 5.2e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 KFX99809.1 - 1.1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KFX99809.1 - 6.2e-10 39.5 0.0 1.9e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 KFX99809.1 - 1.7e-08 34.5 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) T2SSC PF11356.8 KFX99818.1 - 0.025 14.5 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Type II secretion system protein C APH PF01636.23 KFX99820.1 - 4.3e-05 23.6 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family TM1506 PF08973.10 KFX99820.1 - 0.16 11.7 0.0 0.71 9.5 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1893) Tetraspanin PF00335.20 KFX99821.1 - 7.5e-06 25.8 0.3 1.9e-05 24.5 0.3 1.8 1 1 0 1 1 1 1 Tetraspanin family ARL6IP6 PF15062.6 KFX99821.1 - 0.12 12.5 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Baculo_p74_N PF08404.10 KFX99821.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Xan_ur_permease PF00860.20 KFX99822.1 - 2e-21 76.2 32.5 1e-20 73.8 32.5 2.2 1 1 0 1 1 1 1 Permease family QRPTase_C PF01729.19 KFX99823.1 - 1.3e-56 191.0 0.1 1.7e-56 190.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KFX99823.1 - 8.3e-17 61.0 0.0 4.4e-16 58.7 0.0 2.2 3 1 1 4 4 4 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.22 KFX99823.1 - 0.04 13.7 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase KDGP_aldolase PF07071.11 KFX99823.1 - 0.11 12.3 0.1 0.7 9.7 0.1 2.1 2 0 0 2 2 2 0 KDGP aldolase ADH_N PF08240.12 KFX99824.1 - 1.9e-09 37.3 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX99824.1 - 5.9e-06 26.3 0.8 5.9e-06 26.3 0.8 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3237 PF11578.8 KFX99825.1 - 3.3e-25 88.7 0.0 4.3e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4470 PF14737.6 KFX99826.1 - 1.1e-26 92.8 0.2 2.4e-26 91.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Ank_2 PF12796.7 KFX99832.1 - 9.5e-32 109.4 14.0 5.8e-11 42.8 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99832.1 - 3.9e-23 81.5 0.3 8.3e-06 26.2 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX99832.1 - 5.9e-20 71.1 4.4 2.2e-07 31.0 0.1 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX99832.1 - 1.5e-17 61.9 3.4 0.08 13.5 0.0 7.9 8 0 0 8 8 7 5 Ankyrin repeat Ank PF00023.30 KFX99832.1 - 9.5e-12 44.8 7.8 0.052 14.0 0.2 7.0 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 KFX99832.1 - 1e-07 32.0 0.0 1.1e-06 28.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KFX99832.1 - 1.5e-06 28.7 0.0 4.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KFX99832.1 - 0.00012 21.5 7.0 0.00046 19.6 4.5 2.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KFX99832.1 - 0.02 15.2 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFX99832.1 - 0.16 12.4 0.0 5.2 7.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SesA PF17107.5 KFX99832.1 - 3.6 7.8 7.0 0.52 10.5 0.7 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ANAPC8 PF04049.13 KFX99834.1 - 8.9e-37 126.3 0.0 3e-36 124.6 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KFX99834.1 - 1.2e-22 78.7 7.0 9.3e-05 22.1 0.1 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFX99834.1 - 9.7e-18 62.8 13.1 0.0069 16.4 0.2 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX99834.1 - 2.4e-17 61.6 7.5 4.4e-05 23.4 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX99834.1 - 6e-16 57.8 19.5 0.043 14.7 0.1 9.6 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFX99834.1 - 2.5e-10 39.9 2.5 0.0012 18.4 0.1 4.9 3 1 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 KFX99834.1 - 7.8e-09 35.3 2.0 3.4 8.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX99834.1 - 2.2e-08 34.5 12.0 0.0028 18.1 0.0 6.5 6 2 3 9 9 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX99834.1 - 1.1e-07 31.9 7.8 0.034 14.3 0.0 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX99834.1 - 8.5e-07 28.6 13.0 0.12 12.5 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX99834.1 - 4e-06 27.0 16.0 0.019 15.3 1.9 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX99834.1 - 3.6e-05 23.9 14.1 0.83 9.9 1.2 6.4 6 1 1 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFX99834.1 - 3.8e-05 24.2 13.2 4.4e-05 24.0 2.1 5.2 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX99834.1 - 0.0031 18.0 11.9 1.9 9.3 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX99834.1 - 0.0059 16.5 11.5 7.5 6.6 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 KFX99834.1 - 0.013 15.6 1.5 0.15 12.2 0.1 2.9 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_15 PF13429.6 KFX99834.1 - 0.021 14.0 0.3 0.25 10.5 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFX99834.1 - 2.5 8.2 6.0 36 4.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KFX99836.1 - 3.2e-42 144.7 0.0 5.7e-40 137.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99836.1 - 5.1e-25 88.2 0.0 1.6e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S4 PF00163.19 KFX99837.1 - 8.8e-05 23.4 0.1 0.00013 22.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain WH2 PF02205.20 KFX99843.1 - 8.2e-06 25.5 0.9 2.4e-05 24.0 0.9 1.8 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.19 KFX99844.1 - 2.1e-21 75.5 0.0 2.9e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-RVT PF13966.6 KFX99845.1 - 0.054 14.2 0.7 0.12 13.2 0.7 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase fn3_2 PF16893.5 KFX99846.1 - 2.1e-39 133.5 0.0 3.7e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KFX99846.1 - 4.6e-24 84.1 0.5 7.8e-24 83.4 0.5 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KFX99846.1 - 5.7e-12 45.4 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KFX99846.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KFX99846.1 - 0.00064 19.9 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KFX99846.1 - 0.0018 18.6 0.1 0.0075 16.6 0.1 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KFX99846.1 - 0.0027 18.1 0.0 0.0061 16.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SURF2 PF05477.11 KFX99846.1 - 0.19 11.4 3.4 0.29 10.8 3.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) adh_short PF00106.25 KFX99847.1 - 3.1e-07 30.1 0.0 4.3e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX99847.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain CBM_6 PF03422.15 KFX99847.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SEN1_N PF12726.7 KFX99848.1 - 4e-200 666.8 2.4 5.5e-200 666.4 2.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KFX99848.1 - 1.8e-69 234.4 0.6 1.8e-69 234.4 0.6 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KFX99848.1 - 5.3e-58 195.9 0.0 9.9e-58 195.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX99848.1 - 1.1e-07 31.8 0.0 0.00091 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFX99848.1 - 4.9e-07 30.2 0.0 1.8e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KFX99848.1 - 1.5e-06 28.0 0.0 0.00034 20.3 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KFX99848.1 - 2.8e-06 27.3 1.1 0.093 12.5 0.0 4.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KFX99848.1 - 0.025 14.3 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Syntaxin PF00804.25 KFX99848.1 - 0.33 10.6 5.1 0.95 9.1 0.2 3.1 2 0 0 2 2 2 0 Syntaxin Annexin PF00191.20 KFX99848.1 - 0.48 10.5 2.1 0.8 9.8 0.0 2.5 3 0 0 3 3 3 0 Annexin PhoLip_ATPase_C PF16212.5 KFX99849.1 - 1.2e-81 274.2 26.0 1.2e-81 274.2 26.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX99849.1 - 1.2e-19 69.8 0.4 1.2e-19 69.8 0.4 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFX99849.1 - 2.1e-12 47.8 3.8 1.4e-08 35.2 0.2 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX99849.1 - 1.1e-11 44.7 0.0 4.7e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFX99849.1 - 9.3e-05 22.0 0.0 0.0023 17.5 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX99849.1 - 0.02 14.6 0.2 0.062 13.0 0.2 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 KFX99849.1 - 0.55 10.3 8.1 2.1 8.5 8.1 2.1 1 0 0 1 1 1 0 C-terminus of AA_permease FAM178 PF14816.6 KFX99850.1 - 0.0017 17.4 0.3 0.0029 16.6 0.3 1.3 1 0 0 1 1 1 1 Family of unknown function, FAM178 vATP-synt_E PF01991.18 KFX99851.1 - 5.9e-63 211.9 10.5 6.8e-63 211.7 10.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 KFX99851.1 - 0.16 11.8 3.4 0.31 10.9 3.4 1.5 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2987 PF11205.8 KFX99851.1 - 0.44 10.5 5.1 0.24 11.3 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) NMD3 PF04981.13 KFX99851.1 - 1.4 8.3 5.2 4.8 6.6 2.5 2.1 2 0 0 2 2 2 0 NMD3 family YscO-like PF16789.5 KFX99851.1 - 2.1 8.3 17.7 4 7.5 2.0 2.2 1 1 1 2 2 2 0 YscO-like protein FCH PF00611.23 KFX99853.1 - 1.8e-10 41.0 0.4 5.5e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cys_Met_Meta_PP PF01053.20 KFX99853.1 - 0.13 10.7 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4407 PF14362.6 KFX99853.1 - 0.48 9.7 6.8 0.083 12.2 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ras PF00071.22 KFX99855.1 - 8e-54 181.6 0.0 9.1e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX99855.1 - 2.5e-21 76.1 0.0 3.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX99855.1 - 9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Mur_ligase_C PF02875.21 KFX99855.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RRM_1 PF00076.22 KFX99856.1 - 3.4e-10 39.6 0.0 7.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 KFX99857.1 - 2.1e-83 279.5 4.4 2.6e-83 279.3 4.4 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFX99857.1 - 2.4e-05 24.2 0.0 5.7e-05 23.0 0.0 1.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase DUF3464 PF11947.8 KFX99857.1 - 2.8 7.7 4.4 5.1 6.8 4.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CENP-T_C PF15511.6 KFX99858.1 - 1.5e-44 150.6 0.6 3.1e-44 149.5 0.0 1.9 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFX99858.1 - 6.4e-09 36.1 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFX99858.1 - 4.8e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX99858.1 - 7.8e-05 23.0 0.0 0.00025 21.4 0.0 2.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SURF1 PF02104.15 KFX99859.1 - 1.6e-45 155.5 0.0 2.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 KFX99860.1 - 5.7e-14 52.1 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain CDC27 PF09507.10 KFX99860.1 - 0.071 12.5 15.5 0.1 12.0 15.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VSG_B PF13206.6 KFX99860.1 - 0.2 10.8 10.5 0.29 10.3 10.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF3807 PF12720.7 KFX99860.1 - 2.1 8.6 14.0 3.7 7.8 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2076 PF09849.9 KFX99861.1 - 2e-07 31.3 11.2 2.3e-07 31.1 11.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KFX99861.1 - 0.00011 22.2 6.5 0.00015 21.8 6.5 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFX99861.1 - 0.019 15.0 3.6 0.029 14.4 3.6 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 KFX99861.1 - 0.039 14.2 3.1 0.059 13.6 3.1 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Hus1 PF04005.12 KFX99861.1 - 0.078 12.1 0.0 0.094 11.8 0.0 1.0 1 0 0 1 1 1 0 Hus1-like protein Sas10_Utp3 PF04000.15 KFX99862.1 - 2.1e-16 60.3 0.1 2.1e-16 60.3 0.1 2.7 2 1 0 2 2 2 1 Sas10/Utp3/C1D family SRP-alpha_N PF04086.13 KFX99862.1 - 0.22 11.4 23.5 0.27 11.1 23.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2868 PF11067.8 KFX99862.1 - 1 8.8 3.9 1.9 7.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4604 PF15377.6 KFX99862.1 - 1.7 9.0 28.9 2.6 8.4 28.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Hamartin PF04388.12 KFX99862.1 - 3.1 6.4 12.2 3.5 6.2 12.2 1.1 1 0 0 1 1 1 0 Hamartin protein dsDNA_bind PF01984.20 KFX99863.1 - 6.8e-40 135.8 7.6 1.4e-39 134.8 7.6 1.6 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA_C PF08546.11 KFX99863.1 - 1.2e-20 74.0 0.0 2.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFX99863.1 - 8.3e-17 61.2 0.0 2.1e-16 59.9 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA cwf18 PF08315.12 KFX99863.1 - 0.93 10.2 5.3 0.19 12.4 0.8 2.1 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor Coq4 PF05019.13 KFX99864.1 - 5.2e-98 326.8 0.0 6.2e-98 326.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 KFX99865.1 - 6.9e-13 49.3 0.0 9.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 SET domain DUF21 PF01595.20 KFX99866.1 - 1.1e-24 87.1 1.2 1.7e-24 86.4 1.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain RRM_1 PF00076.22 KFX99866.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 KFX99866.1 - 0.23 11.9 0.4 60 4.2 0.0 3.2 3 0 0 3 3 3 0 CBS domain DUF2304 PF10066.9 KFX99866.1 - 0.36 11.1 2.0 0.41 10.9 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) PTPRCAP PF15713.5 KFX99866.1 - 0.4 11.0 4.9 0.99 9.7 4.9 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SecE PF00584.20 KFX99867.1 - 1e-14 54.1 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 KFX99868.1 - 8.6e-17 61.2 16.6 0.0001 23.0 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99868.1 - 0.0018 18.6 0.0 0.22 11.8 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 KFX99869.1 - 7.5e-22 77.3 0.5 1.6e-10 41.0 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX99869.1 - 2.1e-14 53.5 0.1 3.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KFX99869.1 - 1.3e-07 31.7 0.2 0.0011 19.0 0.0 2.5 2 0 0 2 2 2 2 SLIDE Semialdhyde_dhC PF02774.18 KFX99870.1 - 2.1e-38 132.2 0.1 2.8e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFX99870.1 - 1.2e-29 103.2 0.0 9.3e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX99870.1 - 0.0084 16.4 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KFX99870.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 KFX99870.1 - 0.087 13.5 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SAICAR_synt PF01259.18 KFX99871.1 - 7.9e-99 330.3 0.0 9.4e-99 330.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Ribosomal_S4e PF00900.20 KFX99872.1 - 1e-36 124.7 0.1 2.4e-36 123.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFX99872.1 - 3.1e-24 84.3 0.1 5.3e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KFX99872.1 - 1.5e-18 66.6 6.9 2.8e-18 65.7 6.9 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KFX99872.1 - 2e-07 30.6 0.0 4.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFX99872.1 - 0.00091 19.1 0.7 0.00091 19.1 0.7 2.9 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.19 KFX99873.1 - 7.3e-63 212.5 0.1 1.1e-62 212.0 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFX99873.1 - 5e-33 113.8 0.0 9.4e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 KFX99873.1 - 0.0032 16.2 0.0 0.0059 15.3 0.0 1.4 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 KFX99873.1 - 0.047 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region BaffR-Tall_bind PF09256.10 KFX99873.1 - 0.24 11.2 0.4 0.43 10.4 0.4 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding RdRP PF05183.12 KFX99874.1 - 1.3e-192 641.6 0.0 1.8e-192 641.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KFX99874.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.19 KFX99891.1 - 3.7e-24 85.9 1.2 8.2e-24 84.8 1.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFX99891.1 - 7.5e-14 51.8 0.0 1.9e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif GET2 PF08690.10 KFX99892.1 - 6.3e-32 111.5 0.0 3e-31 109.3 0.0 1.8 1 1 0 1 1 1 1 GET complex subunit GET2 Abhydrolase_3 PF07859.13 KFX99893.1 - 2.6e-35 122.2 0.0 2.4e-24 86.4 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX99893.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase LIM_bind PF01803.16 KFX99894.1 - 3.5e-74 249.4 0.2 3.5e-74 249.4 0.2 5.5 3 1 3 6 6 6 1 LIM-domain binding protein Vps39_1 PF10366.9 KFX99895.1 - 1.7e-34 118.3 0.0 2.6e-33 114.5 0.0 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFX99895.1 - 1.5e-29 102.6 0.0 4.7e-29 101.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFX99895.1 - 9.3e-14 51.7 0.0 9.9e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFX99895.1 - 0.0003 20.7 0.2 0.0016 18.3 0.2 2.2 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_1 PF00515.28 KFX99895.1 - 0.0017 18.1 2.6 2.3 8.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX99895.1 - 0.042 14.4 0.7 13 6.4 0.2 4.0 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX99895.1 - 0.22 12.2 0.3 7.3 7.3 0.2 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX99895.1 - 0.49 10.7 2.3 50 4.3 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX99895.1 - 0.66 10.2 2.4 6.8 7.0 0.1 3.4 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Gon7 PF08738.10 KFX99896.1 - 2.6e-10 40.3 2.7 2.6e-10 40.3 2.7 1.8 1 1 1 2 2 2 1 Gon7 family HbrB PF08539.11 KFX99897.1 - 6.7e-49 166.1 0.0 1.8e-48 164.8 0.0 1.8 1 0 0 1 1 1 1 HbrB-like AIP3 PF03915.13 KFX99898.1 - 6.8e-159 529.3 2.1 6.8e-159 529.3 2.1 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 PPI_Ypi1 PF07491.11 KFX99898.1 - 1e-23 82.9 0.9 3.5e-23 81.2 0.9 2.0 1 0 0 1 1 1 1 Protein phosphatase inhibitor Lectin_N PF03954.14 KFX99898.1 - 0.59 9.9 3.5 0.4 10.4 0.2 2.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DivIC PF04977.15 KFX99898.1 - 5.7 6.8 5.7 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator LsmAD PF06741.13 KFX99900.1 - 9e-27 93.4 4.3 9e-27 93.4 4.3 2.4 2 0 0 2 2 2 1 LsmAD domain DUF3018 PF11455.8 KFX99900.1 - 0.95 9.4 4.0 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) Nipped-B_C PF12830.7 KFX99911.1 - 1.2e-30 106.9 2.6 3.4e-28 98.9 0.1 3.6 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFX99911.1 - 3.7e-07 30.3 0.4 3.7e-07 30.3 0.4 3.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 KFX99911.1 - 0.0012 17.6 3.0 0.29 9.6 1.7 3.3 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 KFX99911.1 - 0.0044 17.2 8.9 25 5.5 0.1 6.9 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KFX99911.1 - 0.0052 16.8 1.1 0.048 13.7 0.3 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 KFX99911.1 - 0.0068 15.0 3.8 3.9 5.9 0.0 4.5 5 0 0 5 5 5 2 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KFX99911.1 - 0.011 16.2 0.4 16 6.2 0.1 4.6 3 1 0 3 3 3 0 HEAT-like repeat DUF3788 PF12663.7 KFX99912.1 - 0.11 12.5 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) SEEEED PF14797.6 KFX99913.1 - 0.08 13.1 3.8 0.11 12.6 3.8 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex PspC PF04024.12 KFX99913.1 - 4.4 7.2 5.1 13 5.7 0.3 2.8 3 0 0 3 3 3 0 PspC domain Forkhead PF00250.18 KFX99914.1 - 3.5e-33 113.7 0.0 7.4e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain DDE_1 PF03184.19 KFX99915.1 - 1e-15 57.8 0.1 3e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Transcrip_act PF04949.13 KFX99915.1 - 0.06 13.2 2.7 0.1 12.5 2.7 1.2 1 0 0 1 1 1 0 Transcriptional activator SCHIP-1 PF10148.9 KFX99915.1 - 0.44 10.1 5.5 0.7 9.5 5.5 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 DUF3295 PF11702.8 KFX99917.1 - 6.8e-86 289.6 33.5 8.8e-57 193.6 15.6 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KFX99917.1 - 1.8e-09 37.2 3.4 1.8e-09 37.2 3.4 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Syntaxin PF00804.25 KFX99918.1 - 4.3e-18 65.7 11.1 9e-18 64.7 9.6 2.1 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KFX99918.1 - 8.9e-10 38.4 2.1 1.2e-09 38.0 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Allexi_40kDa PF05549.11 KFX99918.1 - 0.066 12.7 0.1 0.066 12.7 0.1 2.5 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF2207 PF09972.9 KFX99918.1 - 0.082 11.7 1.1 0.15 10.8 0.0 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SP_C-Propep PF08999.10 KFX99918.1 - 0.12 12.2 1.3 0.27 11.0 1.3 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF4448 PF14610.6 KFX99918.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) F-box-like PF12937.7 KFX99919.1 - 1e-06 28.5 0.0 3.5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX99919.1 - 2.6e-05 24.0 0.0 9.2e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 F-box domain Mod_r PF07200.13 KFX99920.1 - 0.81 9.8 9.9 0.71 10.0 4.7 2.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APH PF01636.23 KFX99921.1 - 5.1e-13 49.5 0.3 1.6e-11 44.6 0.0 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX99921.1 - 0.021 14.4 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase DdrB PF12747.7 KFX99921.1 - 0.028 14.2 0.3 0.05 13.4 0.3 1.3 1 0 0 1 1 1 0 DdrB-like protein DUF3432 PF11914.8 KFX99922.1 - 0.038 14.2 1.6 0.066 13.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) DUF2459 PF09601.10 KFX99922.1 - 0.039 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) Methyltransf_23 PF13489.6 KFX99923.1 - 1.2e-15 57.7 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX99923.1 - 1.9e-08 34.9 0.0 1.2e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99923.1 - 3.6e-08 33.4 0.0 2.4e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99923.1 - 4e-05 24.2 0.0 0.0002 22.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX99923.1 - 0.00091 18.8 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KFX99923.1 - 0.0012 18.2 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KFX99923.1 - 0.0038 17.9 0.0 0.013 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX99923.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Daxx PF03344.15 KFX99923.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain FtsJ PF01728.19 KFX99923.1 - 0.038 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KFX99923.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KFX99923.1 - 0.14 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SUR7 PF06687.12 KFX99924.1 - 5.3e-11 42.6 15.7 8.2e-11 41.9 15.7 1.3 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 KFX99924.1 - 6.5 6.6 19.0 0.12 12.2 10.3 2.4 2 2 0 2 2 2 0 Amastin surface glycoprotein Chromo PF00385.24 KFX99925.1 - 2.5e-10 40.1 0.4 4.5e-10 39.3 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Forkhead PF00250.18 KFX99926.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Forkhead domain BAH PF01426.18 KFX99928.1 - 6.5e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KFX99928.1 - 0.0054 16.6 4.2 0.0062 16.4 1.3 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.11 KFX99928.1 - 0.031 14.6 1.1 0.1 12.9 0.1 2.2 2 0 0 2 2 2 0 RING-like domain zf-MIZ PF02891.20 KFX99930.1 - 3.7e-11 42.6 0.1 7.3e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFX99930.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PINIT PF14324.6 KFX99930.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 PINIT domain DUF3295 PF11702.8 KFX99932.1 - 3.7e-75 254.2 45.2 4.5e-33 115.4 9.6 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KFX99932.1 - 9.1e-05 22.2 2.2 0.00017 21.3 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.31 KFX99934.1 - 6.3e-13 48.7 6.4 3.4e-10 40.0 0.1 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX99934.1 - 1.4e-05 25.2 2.4 0.0076 16.5 0.0 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain AGOG PF09171.10 KFX99934.1 - 0.069 12.5 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase p450 PF00067.22 KFX99946.1 - 3.1e-12 46.0 0.0 3.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Hsk3 PF08227.11 KFX99947.1 - 6.1e-21 74.5 0.6 8e-21 74.1 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 KFX99947.1 - 0.2 10.4 0.0 0.24 10.1 0.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF262 PF03235.14 KFX99949.1 - 1.1e-16 61.7 0.0 5.5e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF29 PF01724.16 KFX99949.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF29 Ipi1_N PF12333.8 KFX99950.1 - 3.5e-27 95.0 0.1 1.2e-26 93.3 0.0 2.0 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 KFX99951.1 - 1.3e-06 28.1 0.0 6.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain DUF3275 PF11679.8 KFX99951.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) BTB PF00651.31 KFX99975.1 - 0.001 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KFX99976.1 - 0.00015 22.1 3.1 0.0053 17.1 0.4 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX99976.1 - 0.0046 17.7 0.2 0.0085 16.9 0.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger AAA_13 PF13166.6 KFX99976.1 - 0.024 13.3 0.1 0.024 13.3 0.1 1.0 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.12 KFX99976.1 - 0.077 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 KFX99976.1 - 0.92 9.3 3.1 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KFX99976.1 - 1.2 9.7 5.2 10 6.8 5.2 2.1 1 1 0 1 1 1 0 Zinc finger, C2H2 type GTP_EFTU PF00009.27 KFX99979.1 - 3.7e-55 186.5 0.1 7.1e-55 185.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFX99979.1 - 3e-18 66.1 0.0 9.7e-18 64.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFX99979.1 - 6.3e-18 64.9 1.7 6.3e-18 64.9 1.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF3435 PF11917.8 KFX99979.1 - 2.8e-12 46.3 0.1 6.9e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MMR_HSR1 PF01926.23 KFX99979.1 - 8.5e-05 22.6 0.1 0.00022 21.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX99979.1 - 0.0071 16.3 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase FA PF08736.11 KFX99979.1 - 0.095 12.8 0.3 0.61 10.2 0.0 2.5 2 0 0 2 2 2 0 FERM adjacent (FA) DUF4598 PF15370.6 KFX99980.1 - 9.9e-19 67.9 8.3 9.9e-19 67.9 8.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) IF4E PF01652.18 KFX99981.1 - 1.5e-37 128.8 0.0 2e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Las1 PF04031.13 KFX99982.1 - 4.5e-55 186.0 0.0 6.8e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Las1-like Alb1 PF09135.11 KFX99983.1 - 8.8e-26 90.8 15.9 1.3e-25 90.3 15.9 1.2 1 0 0 1 1 1 1 Alb1 UCH PF00443.29 KFX99984.1 - 4.1e-40 137.9 0.1 8.7e-40 136.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX99984.1 - 1.1e-07 31.8 0.2 5.7e-07 29.4 0.2 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COMPASS-Shg1 PF05205.12 KFX99985.1 - 8e-24 84.3 0.2 8e-24 84.3 0.2 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRCH PF03967.13 KFX99985.1 - 0.23 11.7 2.1 0.26 11.5 0.2 2.1 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region IF-2B PF01008.17 KFX99987.1 - 3.8e-78 262.5 0.0 5.2e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lactamase_B PF00753.27 KFX99987.1 - 2.3e-14 53.9 2.9 6.7e-13 49.1 2.9 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KFX99987.1 - 1.8e-11 44.4 0.0 4.9e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KFX99987.1 - 0.054 13.0 0.6 0.77 9.2 0.6 2.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RRG8 PF17068.5 KFX99987.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial NAD_kinase PF01513.21 KFX99988.1 - 1.9e-69 234.1 0.0 4.8e-69 232.8 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFX99988.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cupin_3 PF05899.12 KFX99988.1 - 0.061 13.0 0.0 6.2 6.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PBP PF01161.20 KFX99995.1 - 6e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 KFX99996.1 - 4.4e-46 157.0 0.0 5.7e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family RhoGAP PF00620.27 KFX99997.1 - 3.1e-12 46.6 0.0 5.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.28 KFX99998.1 - 3.6e-21 75.4 10.0 3.1e-08 33.9 0.2 4.3 4 0 0 4 4 4 3 CBS domain Arm PF00514.23 KFX99999.1 - 1.5e-73 240.8 33.7 4.4e-13 48.8 0.1 11.3 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFX99999.1 - 1.3e-18 67.0 14.9 1.8e-06 28.3 0.3 7.7 6 1 2 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 KFX99999.1 - 5.7e-17 61.9 10.2 0.00027 21.3 0.1 7.0 3 1 4 7 7 7 5 HEAT repeats HEAT PF02985.22 KFX99999.1 - 1.5e-15 56.0 16.1 0.052 13.8 0.3 8.9 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 KFX99999.1 - 1.7e-12 46.7 9.2 2.6e-08 32.9 0.5 2.8 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KFX99999.1 - 1.7e-10 40.8 6.8 2e-05 24.2 3.4 2.7 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 KFX99999.1 - 7.2e-10 38.6 2.8 6.8e-05 22.3 0.5 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 KFX99999.1 - 1.8e-09 36.4 0.6 3.9e-09 35.3 0.3 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KFX99999.1 - 7.2e-06 26.1 9.0 0.019 15.0 0.8 4.9 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KFX99999.1 - 0.0001 22.3 8.9 1.2 9.1 0.0 4.4 2 1 3 5 5 5 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KFX99999.1 - 0.00012 22.2 3.1 2.3 8.4 0.2 5.1 2 1 4 6 6 6 1 V-ATPase subunit H DUF5578 PF17741.1 KFX99999.1 - 0.00015 21.3 6.9 0.86 9.0 0.0 4.8 1 1 3 5 5 5 2 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 KFX99999.1 - 0.00084 19.8 6.7 2.8 8.9 0.6 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat IFRD PF05004.13 KFX99999.1 - 0.0015 17.7 6.1 1.8 7.6 0.1 4.2 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KFX99999.1 - 0.0054 16.7 2.3 1.5 8.8 0.2 3.2 2 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KFX99999.1 - 0.044 14.4 0.2 1.2 9.8 0.1 3.3 2 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Vpu PF00558.19 KFX99999.1 - 0.062 13.1 2.0 0.095 12.5 0.4 2.1 2 0 0 2 2 2 0 Vpu protein RTP1_C1 PF10363.9 KFX99999.1 - 0.21 11.8 5.4 62 3.8 0.0 4.7 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KFX99999.1 - 0.48 10.5 10.4 2.7 8.1 0.2 4.4 3 2 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Peptidase_S24 PF00717.23 KFY00001.1 - 5.4e-10 39.1 0.4 9.7e-10 38.3 0.4 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFY00001.1 - 9.4e-05 22.2 0.0 0.0043 16.8 0.0 2.3 1 1 0 2 2 2 2 Signal peptidase, peptidase S26 KH_1 PF00013.29 KFY00003.1 - 2.8e-48 161.6 14.8 1.3e-16 60.1 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFY00003.1 - 2.1e-11 43.5 5.0 0.0088 15.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFY00003.1 - 4e-09 36.2 5.5 0.042 13.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFY00003.1 - 0.00033 20.7 4.2 1.2 9.3 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFY00003.1 - 0.12 12.4 0.0 8.6 6.4 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain PROL5-SMR PF15621.6 KFY00003.1 - 8.2 7.0 9.6 0.19 12.3 1.9 2.2 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family TIP49 PF06068.13 KFY00004.1 - 4.2e-167 555.7 0.1 5.4e-167 555.4 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFY00004.1 - 1.8e-23 82.4 0.1 4.4e-23 81.2 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFY00004.1 - 8.1e-11 42.5 0.3 1.4e-06 28.8 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY00004.1 - 4.4e-09 36.3 0.1 6.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFY00004.1 - 2e-05 24.9 0.2 0.26 11.5 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFY00004.1 - 5e-05 23.3 0.2 0.036 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFY00004.1 - 6e-05 23.5 0.1 0.00072 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFY00004.1 - 0.0002 21.7 0.1 0.00048 20.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFY00004.1 - 0.00027 21.3 1.6 0.06 13.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFY00004.1 - 0.00065 19.4 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KFY00004.1 - 0.00068 19.3 0.1 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFY00004.1 - 0.0075 15.6 0.1 0.024 13.9 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KFY00004.1 - 0.0087 15.5 0.1 0.5 9.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFY00004.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFY00004.1 - 0.025 15.1 0.1 0.073 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KFY00004.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KFY00004.1 - 0.027 13.8 0.2 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KFY00004.1 - 0.031 14.3 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFY00004.1 - 0.036 13.8 0.2 0.83 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFY00004.1 - 0.059 12.9 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DnaB_C PF03796.15 KFY00004.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFY00004.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 KFY00004.1 - 0.17 12.0 0.0 4 7.6 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 KFY00004.1 - 0.19 11.2 1.0 1 8.8 0.1 2.5 3 0 0 3 3 3 0 PhoH-like protein HMG_box PF00505.19 KFY00005.1 - 5.6e-21 74.7 1.2 1.1e-20 73.8 1.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFY00005.1 - 9.2e-07 29.4 0.3 1.6e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFY00005.1 - 0.005 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box CHDNT PF08073.12 KFY00005.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain Glyco_hydro_63 PF03200.16 KFY00006.1 - 4.8e-09 35.5 6.6 6.8e-07 28.4 0.0 3.9 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Host_attach PF10116.9 KFY00006.1 - 0.039 14.5 0.2 0.084 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells DNA_pol3_delta2 PF13177.6 KFY00007.1 - 3.6e-11 43.1 0.0 6.6e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFY00007.1 - 1.5e-06 28.7 0.0 3.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFY00007.1 - 3.9e-05 24.0 0.2 0.00018 21.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFY00007.1 - 0.00041 20.8 0.9 0.011 16.1 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KFY00007.1 - 0.0011 18.7 0.5 0.0034 17.1 0.5 1.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 KFY00007.1 - 0.0028 18.0 0.3 0.0097 16.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KFY00007.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 KFY00007.1 - 0.014 15.9 0.1 0.025 15.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KFY00007.1 - 0.052 12.3 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Shugoshin_N PF07558.11 KFY00008.1 - 2.7e-17 62.3 3.6 5.3e-17 61.4 3.6 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KFY00008.1 - 6.3e-12 45.1 4.6 6.3e-12 45.1 4.6 3.2 2 0 0 2 2 2 1 Shugoshin C terminus DASH_Dad2 PF08654.10 KFY00009.1 - 2.3e-34 117.8 0.3 3.6e-34 117.1 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 COesterase PF00135.28 KFY00011.1 - 5.5e-88 296.1 0.0 6.2e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY00011.1 - 0.00015 21.7 0.7 0.00084 19.3 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY00011.1 - 0.0019 17.7 0.0 0.0097 15.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family NFACT-R_1 PF05670.13 KFY00012.1 - 9e-09 36.0 0.3 2.2e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain GvpL_GvpF PF06386.11 KFY00012.1 - 0.2 11.5 3.6 0.26 11.2 3.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1764 PF08576.10 KFY00012.1 - 9.8 7.1 9.4 19 6.2 9.2 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L3 PF00297.22 KFY00013.1 - 8.6e-13 48.0 4.7 1.2e-09 37.7 1.8 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 KFY00014.1 - 1.1e-39 134.7 0.0 1.4e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Phage_GP20 PF06810.11 KFY00017.1 - 1.4e-06 28.2 5.7 1.4e-06 28.2 5.7 11.0 4 2 7 11 11 10 3 Phage minor structural protein GP20 GAS PF13851.6 KFY00017.1 - 2.5e-06 27.0 124.6 0.029 13.7 20.0 8.5 3 2 4 8 8 8 4 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFY00017.1 - 0.00011 22.3 146.5 0.0026 17.8 17.1 8.8 4 2 5 9 9 8 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KFY00017.1 - 0.0002 19.1 40.3 0.0002 19.1 40.3 4.3 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) Spc7 PF08317.11 KFY00017.1 - 0.0008 18.4 22.2 0.0008 18.4 22.2 7.6 2 2 4 7 7 7 4 Spc7 kinetochore protein TSC22 PF01166.18 KFY00017.1 - 0.00097 19.4 0.3 0.00097 19.4 0.3 9.2 6 2 2 8 8 8 3 TSC-22/dip/bun family DUF4407 PF14362.6 KFY00017.1 - 0.0028 17.1 17.9 0.0028 17.1 17.9 6.9 1 1 4 6 6 3 1 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 KFY00017.1 - 0.0033 16.4 41.6 0.0033 16.4 41.6 7.3 3 2 4 7 7 6 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4164 PF13747.6 KFY00017.1 - 0.0058 16.9 4.4 0.0058 16.9 4.4 11.3 5 2 7 12 12 10 1 Domain of unknown function (DUF4164) APG6_N PF17675.1 KFY00017.1 - 0.0084 16.6 17.3 0.0084 16.6 17.3 9.6 4 4 6 10 10 8 2 Apg6 coiled-coil region Bap31_Bap29_C PF18035.1 KFY00017.1 - 0.0092 16.0 1.1 0.0092 16.0 1.1 10.4 6 3 2 8 8 6 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1664 PF07889.12 KFY00017.1 - 0.017 15.2 1.1 0.017 15.2 1.1 9.1 3 2 6 11 11 10 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KFY00017.1 - 0.033 14.6 42.4 3.1 8.3 0.8 9.3 5 4 4 9 9 8 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 KFY00017.1 - 0.046 13.5 0.5 0.046 13.5 0.5 12.8 6 3 8 14 14 14 0 Septum formation initiator BLOC1_2 PF10046.9 KFY00017.1 - 0.053 13.8 80.4 0.15 12.4 7.4 10.8 4 2 5 10 10 10 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.7 KFY00017.1 - 0.057 13.0 116.8 0.36 10.3 9.0 8.3 4 2 3 7 7 7 0 Mechanosensitive ion channel porin domain KASH_CCD PF14662.6 KFY00017.1 - 0.062 13.1 121.4 0.064 13.1 21.3 6.7 2 2 3 6 6 6 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 KFY00017.1 - 0.083 13.1 67.4 0.03 14.5 8.5 8.5 2 2 5 8 8 8 0 Fibrinogen alpha/beta chain family Cep57_CLD PF14073.6 KFY00017.1 - 0.11 12.5 0.1 0.11 12.5 0.1 7.6 4 1 1 7 7 7 0 Centrosome localisation domain of Cep57 Shugoshin_N PF07558.11 KFY00017.1 - 0.12 12.3 15.2 0.31 11.0 0.0 6.4 5 1 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Surfac_D-trimer PF09006.11 KFY00017.1 - 0.74 9.8 3.2 4.6 7.2 0.0 4.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation HOOK PF05622.12 KFY00017.1 - 0.87 7.7 126.3 1.2 7.2 2.1 6.2 3 2 2 5 5 5 0 HOOK protein Leu_zip PF15294.6 KFY00017.1 - 1.1 8.8 106.2 0.027 14.0 6.3 6.6 2 2 3 6 6 6 0 Leucine zipper Fez1 PF06818.15 KFY00017.1 - 2.4 8.5 136.5 0.34 11.3 13.3 8.1 1 1 7 8 8 7 0 Fez1 HMMR_N PF15905.5 KFY00017.1 - 2.7 7.4 120.1 0.44 10.0 8.6 7.7 3 2 4 7 7 7 0 Hyaluronan mediated motility receptor N-terminal HSBP1 PF06825.12 KFY00017.1 - 4.6 7.2 9.4 37 4.3 0.2 5.1 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Pox_A_type_inc PF04508.12 KFY00017.1 - 4.6 7.3 23.9 2.6 8.0 0.1 7.6 7 0 0 7 7 6 0 Viral A-type inclusion protein repeat zinc_ribbon_10 PF10058.9 KFY00018.1 - 2.1e-19 69.0 0.1 3.6e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF2304 PF10066.9 KFY00018.1 - 0.046 13.9 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2207 PF09972.9 KFY00018.1 - 0.056 12.2 0.1 0.081 11.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ima1_N PF09779.9 KFY00018.1 - 2.2 9.2 6.4 1.1 10.1 0.1 3.0 2 1 1 3 3 3 0 Ima1 N-terminal domain YlaH PF14036.6 KFY00019.1 - 0.07 13.5 0.3 0.07 13.5 0.3 2.2 3 0 0 3 3 3 0 YlaH-like protein Kelch_1 PF01344.25 KFY00020.1 - 2.3e-39 132.7 6.9 9.8e-08 31.5 0.0 7.7 8 0 0 8 8 8 5 Kelch motif Kelch_6 PF13964.6 KFY00020.1 - 1e-31 108.1 14.9 3.9e-07 30.1 0.1 7.1 3 2 4 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KFY00020.1 - 1.4e-20 73.1 15.6 5.3e-06 26.6 0.1 6.5 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFY00020.1 - 3.8e-19 68.4 17.5 2.2e-06 27.6 0.0 7.7 7 2 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFY00020.1 - 8.1e-18 64.0 5.2 0.0034 17.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFY00020.1 - 1.5e-16 59.6 4.1 0.0013 18.7 0.0 6.3 7 1 0 7 7 7 5 Kelch motif DUF1668 PF07893.13 KFY00020.1 - 0.0001 21.8 0.1 0.4 10.0 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1668) SH3_9 PF14604.6 KFY00023.1 - 2.5e-08 33.7 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFY00023.1 - 5.4e-07 29.1 0.0 8.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFY00023.1 - 4.6e-06 26.2 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_DNAp_acc PF04929.12 KFY00023.1 - 7.2 5.5 11.7 17 4.3 11.7 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SKG6 PF08693.10 KFY00023.1 - 8.9 5.8 7.2 0.64 9.5 2.1 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Carb_kinase PF01256.17 KFY00025.1 - 0.0048 16.4 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase PARP PF00644.20 KFY00026.1 - 7.5e-11 42.0 0.4 5.2e-10 39.2 0.3 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KFY00026.1 - 4.8e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sds3 PF08598.11 KFY00027.1 - 2.8e-22 79.8 0.5 4.3e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 Sds3-like Nop PF01798.18 KFY00028.1 - 2.5e-79 266.0 0.1 2.5e-79 266.0 0.1 2.4 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFY00028.1 - 6.3e-21 74.5 2.2 6.3e-21 74.5 2.2 3.2 3 0 0 3 3 3 1 NOP5NT (NUC127) domain DUF3653 PF12375.8 KFY00028.1 - 0.084 13.0 0.2 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Phage protein vATP-synt_AC39 PF01992.16 KFY00029.1 - 9e-109 364.0 0.0 1e-108 363.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 KFY00030.1 - 1.1e-25 89.6 0.6 3.2e-25 88.1 0.6 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KFY00031.1 - 1.2e-26 93.3 0.6 1.5e-15 57.0 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KFY00031.1 - 5.3e-11 43.7 15.6 1.8e-10 42.0 15.6 1.9 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus KxDL PF10241.9 KFY00032.1 - 2.3e-28 98.3 2.4 3.5e-28 97.7 2.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein UPF0242 PF06785.11 KFY00032.1 - 0.027 14.6 1.2 0.034 14.3 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF883 PF05957.13 KFY00032.1 - 0.13 12.9 5.5 0.87 10.2 2.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_DE PF00401.20 KFY00032.1 - 2.1 8.7 10.5 2 8.7 7.0 2.2 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DEAD PF00270.29 KFY00034.1 - 3.1e-37 128.0 0.0 7.7e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00034.1 - 2.6e-21 76.0 0.0 8e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFY00034.1 - 5e-20 71.5 0.0 1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFY00034.1 - 0.0044 17.1 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFY00034.1 - 0.68 10.2 4.3 0.67 10.2 0.3 2.8 2 1 0 2 2 2 0 AAA domain DUF3492 PF11997.8 KFY00034.1 - 7 6.3 5.9 13 5.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) ubiquitin PF00240.23 KFY00035.1 - 0.00095 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KFY00035.1 - 0.0023 18.6 0.0 0.0042 17.7 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PseudoU_synth_1 PF01416.20 KFY00036.1 - 1.8e-35 121.6 0.0 9.6e-34 116.1 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.22 KFY00037.1 - 4.7e-16 58.8 0.0 6.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY00037.1 - 7.3e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFY00037.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 KFY00037.1 - 0.017 14.6 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RNA_helicase PF00910.22 KFY00037.1 - 0.027 14.9 0.0 0.057 13.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase G-alpha PF00503.20 KFY00037.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KFY00037.1 - 0.14 12.3 0.0 0.45 10.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KFY00037.1 - 0.16 12.5 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_pol_Rpb4 PF03874.16 KFY00038.1 - 4.4e-18 65.8 0.0 6.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pribosyl_synth PF14572.6 KFY00039.1 - 1.9e-41 142.1 2.2 6.1e-36 124.2 0.3 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFY00039.1 - 3.1e-31 107.7 0.0 7.2e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFY00039.1 - 3e-13 49.6 0.3 4.8e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SNRNP27 PF08648.12 KFY00040.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Ribosomal_L21p PF00829.21 KFY00042.1 - 2.2e-08 34.3 0.0 3.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SpoIIE PF07228.12 KFY00043.1 - 5e-09 36.3 0.2 2.9e-08 33.9 0.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFY00043.1 - 8e-08 32.2 0.9 1.5e-07 31.3 0.9 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFY00043.1 - 3.7e-06 26.8 0.1 0.044 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C DPPIV_N PF00930.21 KFY00044.1 - 1.6e-113 379.0 0.6 2.2e-113 378.7 0.6 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFY00044.1 - 4.4e-56 189.7 2.4 7.5e-56 188.9 2.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFY00044.1 - 3e-07 30.3 1.2 6.5e-06 25.9 0.4 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KFY00044.1 - 0.0023 17.2 0.9 0.19 10.9 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY00044.1 - 0.011 16.4 3.1 0.23 12.0 0.7 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KFY00044.1 - 0.022 13.5 0.0 0.34 9.5 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KFY00044.1 - 0.044 13.4 0.1 0.096 12.3 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KFY00044.1 - 0.066 12.8 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KFY00044.1 - 0.11 11.0 0.0 0.67 8.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II TauD PF02668.16 KFY00045.1 - 1.8e-44 152.6 0.0 2.4e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 KFY00045.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.7 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY Sof1 PF04158.14 KFY00046.1 - 7.9e-30 103.0 18.9 1.4e-29 102.2 18.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFY00046.1 - 9.9e-28 95.8 6.5 3.3e-05 24.6 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00046.1 - 9.8e-10 38.6 0.1 0.019 15.3 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFY00046.1 - 0.00024 21.1 0.3 3.6 7.7 0.0 4.7 2 2 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KFY00046.1 - 0.0019 17.2 0.0 0.062 12.2 0.0 2.8 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFY00046.1 - 0.0031 16.1 0.5 0.086 11.4 0.1 2.8 2 1 0 3 3 3 1 Cytochrome D1 heme domain DUF3288 PF11691.8 KFY00046.1 - 0.067 13.2 0.6 0.18 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) RPN6_N PF18055.1 KFY00047.1 - 8.1e-48 161.6 1.9 2.9e-47 159.8 1.9 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KFY00047.1 - 2.9e-20 72.7 0.3 9e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KFY00047.1 - 1.6e-09 37.3 0.1 3.5e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KFY00047.1 - 0.00058 19.3 2.9 0.00058 19.3 2.9 2.1 1 1 1 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 KFY00047.1 - 0.0055 16.3 0.2 0.011 15.4 0.2 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.6 KFY00047.1 - 0.012 15.6 1.1 3.2 8.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 KFY00047.1 - 0.088 12.8 0.2 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TPR_12 PF13424.6 KFY00047.1 - 0.44 10.9 14.4 10 6.5 1.7 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFY00047.1 - 3.7 8.6 10.2 23 6.1 0.0 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 KFY00053.1 - 1e-48 166.0 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00053.1 - 2.9e-27 95.6 0.3 4.4e-26 91.7 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY00053.1 - 0.074 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFY00053.1 - 0.28 10.4 0.3 0.55 9.5 0.1 1.5 2 0 0 2 2 2 0 Kinase-like SKG6 PF08693.10 KFY00059.1 - 0.14 11.6 3.0 0.24 10.8 3.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GT87 PF09594.10 KFY00059.1 - 0.77 9.4 4.3 0.96 9.1 4.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 ATG13 PF10033.9 KFY00068.1 - 3.8e-70 236.3 0.0 9.6e-70 235.0 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 MFS_1 PF07690.16 KFY00069.1 - 3e-27 95.5 30.3 1.7e-25 89.7 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY00069.1 - 0.0057 15.1 1.5 0.0057 15.1 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3054 PF11255.8 KFY00069.1 - 3.6 8.2 11.8 0.83 10.2 2.3 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3054) MFS_1 PF07690.16 KFY00071.1 - 4.3e-38 131.1 33.5 4.3e-38 131.1 33.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00071.1 - 2e-07 30.3 12.1 2e-07 30.3 12.1 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter Copper-fist PF00649.18 KFY00072.1 - 3.7e-19 67.9 1.9 3.7e-19 67.9 1.9 2.9 1 1 2 3 3 3 1 Copper fist DNA binding domain Fungal_TACC PF12709.7 KFY00077.1 - 1.1e-11 45.0 14.1 2.4e-10 40.7 0.6 3.9 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins FPP PF05911.11 KFY00077.1 - 0.00041 18.7 15.6 0.0068 14.7 2.5 2.8 3 0 0 3 3 3 2 Filament-like plant protein, long coiled-coil Macoilin PF09726.9 KFY00077.1 - 0.013 14.1 12.7 0.0037 15.9 8.9 1.8 1 1 1 2 2 2 0 Macoilin family Shugoshin_N PF07558.11 KFY00077.1 - 0.023 14.6 0.0 0.023 14.6 0.0 3.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 KFY00077.1 - 0.17 12.0 13.1 0.95 9.6 0.6 4.3 4 1 0 4 4 4 0 bZIP transcription factor Tropomyosin PF00261.20 KFY00077.1 - 0.22 10.8 34.9 0.95 8.8 32.3 2.8 2 1 0 2 2 2 0 Tropomyosin DUF4407 PF14362.6 KFY00077.1 - 0.27 10.5 17.5 0.031 13.6 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CAGE1 PF15066.6 KFY00077.1 - 0.37 9.4 5.6 0.3 9.7 0.9 2.3 1 1 0 2 2 2 0 Cancer-associated gene protein 1 family DUF5082 PF16888.5 KFY00077.1 - 0.39 11.0 5.1 0.29 11.4 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 KFY00077.1 - 1.1 9.3 6.7 0.36 10.9 1.3 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation YabA PF06156.13 KFY00077.1 - 9 7.0 15.5 10 6.8 0.6 4.4 2 2 2 4 4 4 0 Initiation control protein YabA Nuf2 PF03800.14 KFY00091.1 - 7.4e-42 142.8 0.0 2.5e-41 141.0 0.0 2.0 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KFY00091.1 - 4.2e-35 120.3 17.9 4.2e-35 120.3 17.9 4.2 3 1 1 4 4 4 2 Designed helical repeat protein 10 domain DUF3287 PF11690.8 KFY00091.1 - 1.7 8.3 14.0 4.5 7.0 4.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) Ndc1_Nup PF09531.10 KFY00091.1 - 4 6.0 7.7 7.2 5.2 7.7 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HWE_HK PF07536.14 KFY00091.1 - 5.9 7.7 12.7 1.7 9.4 0.8 3.9 3 2 1 4 4 4 0 HWE histidine kinase Spc7 PF08317.11 KFY00091.1 - 7.3 5.4 42.7 5.9 5.7 10.0 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DcrB PF08786.11 KFY00091.1 - 9.4 6.3 8.7 3.5 7.7 1.0 3.0 1 1 2 3 3 3 0 DcrB DUF1515 PF07439.11 KFY00092.1 - 0.26 11.3 2.2 0.64 10.1 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Thioredoxin PF00085.20 KFY00093.1 - 3.6e-27 94.4 0.1 4.3e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFY00093.1 - 3.5e-07 30.6 0.1 6e-07 29.9 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFY00093.1 - 1.7e-05 25.0 0.0 7.3e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFY00093.1 - 4.4e-05 23.0 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KFY00093.1 - 0.00027 20.7 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFY00093.1 - 0.0018 18.2 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.11 KFY00093.1 - 0.0091 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 KFY00093.1 - 0.014 15.6 0.2 0.11 12.7 0.0 2.0 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_7 PF13899.6 KFY00093.1 - 0.033 14.4 0.2 0.057 13.6 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KFY00093.1 - 0.06 13.0 0.0 0.099 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 KFY00093.1 - 0.072 12.8 0.1 0.34 10.6 0.1 1.8 1 1 1 2 2 2 0 Redoxin Phosducin PF02114.16 KFY00093.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin OTU PF02338.19 KFY00094.1 - 1.1e-09 38.9 0.0 3.7e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KFY00094.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KFY00094.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Peptidase_C65 PF10275.9 KFY00094.1 - 0.14 11.6 0.0 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain RNA_pol_Rpc4 PF05132.14 KFY00094.1 - 1.9 8.9 7.6 2.5 8.5 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase III RPC4 DAO PF01266.24 KFY00095.1 - 1.4e-35 123.5 4.8 2.2e-35 122.9 4.8 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFY00095.1 - 8.7e-05 21.9 0.7 0.00021 20.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFY00095.1 - 0.00013 22.1 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY00095.1 - 0.0025 17.0 0.0 0.008 15.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY00095.1 - 0.017 14.4 0.1 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFY00095.1 - 0.081 11.8 0.1 0.52 9.1 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 KFY00095.1 - 0.12 12.9 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 KFY00096.1 - 0.00012 22.0 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00096.1 - 0.0012 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFY00096.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFY00096.1 - 0.039 13.1 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein MFS_1 PF07690.16 KFY00098.1 - 5e-18 65.2 32.6 4e-12 45.7 9.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00098.1 - 4.1e-11 42.4 9.2 9.3e-10 37.9 1.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KFY00098.1 - 0.071 12.0 0.2 0.071 12.0 0.2 2.6 2 1 0 3 3 3 0 MFS_1 like family HAD_2 PF13419.6 KFY00099.1 - 6.7e-10 39.3 0.0 1e-09 38.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY00099.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFY00099.1 - 0.00015 22.1 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Fructosamin_kin PF03881.14 KFY00100.1 - 1.3e-32 113.2 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFY00100.1 - 5.9e-07 29.7 0.0 8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF676 PF05057.14 KFY00101.1 - 1.7e-06 27.7 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 KFY00101.1 - 5e-06 26.5 0.0 1.5e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 KFY00101.1 - 1.7e-05 24.7 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 KFY00101.1 - 0.00084 19.8 0.0 0.0032 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KFY00101.1 - 0.0013 19.4 0.7 0.0063 17.2 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family 6PF2K PF01591.18 KFY00101.1 - 0.014 14.7 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase ATPase_2 PF01637.18 KFY00101.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KFY00101.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KFY00101.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KFY00101.1 - 0.1 12.5 0.1 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.32 KFY00101.1 - 0.24 12.4 3.3 33 5.6 0.1 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Hira PF07569.11 KFY00101.1 - 0.48 10.1 2.3 20 4.8 0.0 3.5 4 0 0 4 4 4 0 TUP1-like enhancer of split COPI_assoc PF08507.10 KFY00102.1 - 4e-34 117.5 5.9 4.3e-34 117.4 5.9 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 KFY00102.1 - 0.069 13.5 4.6 0.11 12.9 4.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF2583 PF10762.9 KFY00102.1 - 0.34 11.4 3.1 7.9 7.0 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) TMEM72 PF16054.5 KFY00102.1 - 0.63 9.7 6.2 0.14 11.8 2.5 1.6 2 0 0 2 2 2 0 Transmembrane protein family 72 GATA PF00320.27 KFY00103.1 - 1.1e-29 101.7 15.8 1.2e-14 53.6 3.4 2.5 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 KFY00103.1 - 1.1e-05 25.5 2.0 0.064 13.4 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFY00103.1 - 1.2e-05 24.7 4.6 0.021 14.4 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 KFY00103.1 - 0.0016 18.3 5.4 0.1 12.6 0.4 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ArfGap PF01412.18 KFY00103.1 - 0.0018 18.4 8.0 0.2 11.8 0.2 2.7 3 0 0 3 3 2 2 Putative GTPase activating protein for Arf DZR PF12773.7 KFY00103.1 - 0.0031 17.5 6.1 1.4 9.0 0.2 3.1 2 1 0 2 2 2 2 Double zinc ribbon Auto_anti-p27 PF06677.12 KFY00103.1 - 0.018 15.2 8.8 0.2 11.8 0.6 2.6 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Sec23_Sec24 PF04810.15 KFY00103.1 - 0.027 14.5 7.7 0.036 14.1 0.6 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.17 KFY00103.1 - 0.047 13.6 4.8 1.6 8.6 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.13 KFY00103.1 - 0.21 11.1 1.3 7.4 6.0 0.1 2.3 2 0 0 2 2 2 0 NMD3 family zinc_ribbon_4 PF13717.6 KFY00103.1 - 0.4 10.6 1.5 4.3 7.3 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KFY00103.1 - 2.6 7.8 10.6 9.5 6.0 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain STAC2_u1 PF16664.5 KFY00104.1 - 0.015 15.8 1.6 0.14 12.7 0.0 3.0 1 1 0 3 3 3 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Methyltransf_33 PF10017.9 KFY00105.1 - 2.6e-78 263.3 0.3 1.3e-76 257.7 0.3 2.1 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KFY00105.1 - 3.9e-19 69.3 0.5 2.6e-18 66.5 0.5 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KFY00105.1 - 4e-05 24.1 0.1 0.00013 22.5 0.1 1.9 1 0 0 1 1 1 1 DinB superfamily PI31_Prot_N PF11566.8 KFY00108.1 - 5.9e-63 211.5 0.0 7.3e-63 211.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal adh_short PF00106.25 KFY00109.1 - 3e-53 180.2 0.1 4.1e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00109.1 - 5.6e-35 121.0 0.1 8.1e-35 120.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00109.1 - 3.9e-12 46.4 0.0 6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFY00109.1 - 0.063 13.5 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F-box_4 PF15966.5 KFY00121.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box F-box PF00646.33 KFY00121.1 - 0.039 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KFY00121.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 KFY00124.1 - 4.1e-16 59.1 0.5 4.9e-16 58.9 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00124.1 - 1.2e-08 34.6 0.4 1.4e-08 34.3 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SH2_2 PF14633.6 KFY00125.1 - 2.8e-87 291.7 0.1 6.7e-87 290.4 0.1 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KFY00125.1 - 1.9e-39 134.7 0.6 4.9e-39 133.3 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KFY00125.1 - 9.6e-30 103.0 0.0 4.9e-29 100.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 KFY00125.1 - 1.7e-27 96.1 0.0 6.6e-27 94.1 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KFY00125.1 - 9.8e-19 67.7 20.9 9.8e-19 67.7 20.9 5.7 4 1 3 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KFY00125.1 - 2.7e-05 25.0 2.5 0.00086 20.2 2.5 3.4 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KFY00125.1 - 8.3e-05 22.6 0.0 0.00025 21.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 KFY00125.1 - 0.027 15.0 0.0 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 Tex protein YqgF-like domain HHH_3 PF12836.7 KFY00125.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans PF04082.18 KFY00138.1 - 3.3e-26 91.9 0.0 5.2e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00138.1 - 1e-10 41.5 11.7 1.8e-10 40.8 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pput2613-deam PF14427.6 KFY00138.1 - 0.13 12.2 0.6 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Pput_2613-like deaminase Chitin_bind_1 PF00187.19 KFY00140.1 - 1.5e-05 25.3 19.4 1.5e-05 25.3 19.4 2.3 3 0 0 3 3 3 1 Chitin recognition protein Glyco_hydro_61 PF03443.14 KFY00140.1 - 0.0091 16.0 0.1 0.13 12.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 YuzL PF14115.6 KFY00141.1 - 0.081 13.4 1.3 0.081 13.4 1.3 1.6 2 0 0 2 2 2 0 YuzL-like protein Plasmodium_Vir PF05795.11 KFY00142.1 - 0.022 14.2 0.2 0.03 13.8 0.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TrbC PF04956.13 KFY00142.1 - 0.056 13.7 0.9 0.12 12.6 0.9 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family RNA_pol_Rpc4 PF05132.14 KFY00142.1 - 0.76 10.2 4.0 2 8.8 4.0 1.6 1 1 0 1 1 1 0 RNA polymerase III RPC4 DUF1180 PF06679.12 KFY00142.1 - 1.1 9.6 5.9 1.9 8.9 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1765 PF08578.10 KFY00160.1 - 8e-05 23.1 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Kelch_4 PF13418.6 KFY00185.1 - 2.2e-25 88.4 10.2 1.3e-08 34.6 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KFY00185.1 - 7e-23 80.2 1.6 1.1e-06 28.5 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KFY00185.1 - 2.9e-22 78.1 2.7 2.5e-05 24.4 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KFY00185.1 - 2.6e-19 68.5 1.5 6e-05 22.5 0.0 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KFY00185.1 - 1.6e-16 60.2 12.2 3e-06 27.4 0.2 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KFY00185.1 - 8.3e-15 54.1 2.3 0.0011 18.9 0.0 5.4 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 KFY00185.1 - 1.2e-10 41.6 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Bap31 PF05529.12 KFY00186.1 - 9e-48 161.6 10.4 1.2e-47 161.1 10.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFY00186.1 - 1.6e-14 53.7 2.0 1.6e-14 53.7 2.0 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain She9_MDM33 PF05546.11 KFY00186.1 - 0.0081 16.0 0.9 0.0081 16.0 0.9 1.6 2 0 0 2 2 2 1 She9 / Mdm33 family Filament PF00038.21 KFY00186.1 - 0.011 15.3 2.5 0.017 14.7 2.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KFY00186.1 - 0.012 15.4 5.1 0.02 14.7 0.5 2.8 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 KFY00186.1 - 0.054 13.5 5.3 0.047 13.7 3.8 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4349 PF14257.6 KFY00186.1 - 0.086 12.3 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 KFY00186.1 - 0.15 10.9 2.6 0.23 10.3 2.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KFY00186.1 - 0.16 12.5 3.6 0.31 11.6 3.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Csm1_N PF18504.1 KFY00186.1 - 0.42 11.0 4.6 0.15 12.4 1.2 1.9 1 1 1 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 KFY00186.1 - 0.44 10.6 4.7 0.081 13.0 0.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 KFY00186.1 - 0.92 9.3 8.2 0.27 11.0 2.3 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fungal_trans PF04082.18 KFY00188.1 - 8.2e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00188.1 - 2.4e-10 40.4 5.3 3.7e-10 39.7 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.11 KFY00189.1 - 0.008 16.2 7.0 0.01 15.9 7.0 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal NOA36 PF06524.12 KFY00189.1 - 0.08 12.3 12.9 0.084 12.2 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein Adeno_terminal PF02459.15 KFY00189.1 - 0.26 9.6 8.7 0.33 9.3 8.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDC45 PF02724.14 KFY00189.1 - 1.4 7.2 15.1 1.4 7.1 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KFY00189.1 - 1.6 6.8 19.3 1.5 6.9 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KFY00189.1 - 1.7 8.9 20.2 1.8 8.8 20.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFB6 PF17110.5 KFY00189.1 - 2.1 8.0 7.2 2.1 8.1 7.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 KFY00189.1 - 2.6 7.6 17.2 2.8 7.5 17.2 1.1 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.13 KFY00189.1 - 2.7 6.9 20.2 2.8 6.9 20.2 1.0 1 0 0 1 1 1 0 Paf1 PITH PF06201.13 KFY00199.1 - 2e-35 122.2 0.0 3.2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFY00199.1 - 3.5e-27 94.4 0.1 6.9e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFY00199.1 - 8.2e-08 31.9 0.2 4.6e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFY00199.1 - 2.1e-07 31.2 0.1 6.1e-05 23.3 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFY00199.1 - 1.6e-05 25.3 0.3 7.6e-05 23.1 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFY00199.1 - 0.0022 17.9 0.1 0.0044 16.9 0.1 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFY00199.1 - 0.0026 17.5 0.1 0.0068 16.1 0.1 1.7 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFY00199.1 - 0.0089 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KFY00199.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Suf PF05843.14 KFY00200.1 - 2.7e-06 27.6 3.4 0.012 15.6 0.0 3.0 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFY00200.1 - 1.7e-05 25.3 3.9 0.083 13.7 0.1 5.1 4 3 3 7 7 7 2 Tetratricopeptide repeat DUF202 PF02656.15 KFY00201.1 - 0.0019 18.6 5.2 0.0019 18.6 5.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Zn_clus PF00172.18 KFY00202.1 - 8.9e-08 32.1 6.5 1.4e-07 31.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nsp1_C PF05064.13 KFY00205.1 - 1.5e-38 131.2 2.0 1.5e-38 131.1 0.5 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region Mod_r PF07200.13 KFY00205.1 - 0.0081 16.3 3.8 0.013 15.6 0.1 2.3 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein MIP-T3_C PF17749.1 KFY00205.1 - 0.0099 15.9 2.4 5.6 6.9 0.0 3.3 2 1 1 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region DUF1664 PF07889.12 KFY00205.1 - 0.016 15.2 1.2 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFY00205.1 - 0.019 15.2 1.5 28 5.1 0.0 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein DUF812 PF05667.11 KFY00205.1 - 0.039 12.9 4.4 0.36 9.7 0.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) COG2 PF06148.11 KFY00205.1 - 0.062 13.4 2.4 0.52 10.4 0.4 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.12 KFY00205.1 - 0.07 13.1 4.6 5.4 7.0 0.7 3.0 1 1 2 3 3 3 0 Laminin Domain II RSS_P20 PF11757.8 KFY00205.1 - 0.08 13.4 0.1 0.43 11.1 0.1 2.0 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Baculo_PEP_C PF04513.12 KFY00205.1 - 0.08 13.0 0.6 0.95 9.5 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KFY00205.1 - 0.11 12.8 8.1 0.18 12.1 0.5 2.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 KFY00205.1 - 0.3 11.3 4.7 0.59 10.3 4.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 KFY00205.1 - 0.31 10.8 1.7 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 KFY00205.1 - 0.36 9.6 6.9 0.59 9.0 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 KFY00205.1 - 0.5 10.7 5.0 4.4 7.7 0.2 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HIP1_clath_bdg PF16515.5 KFY00205.1 - 1.1 9.9 6.1 7.7 7.2 1.4 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KFY00205.1 - 2.2 8.8 7.4 15 6.1 3.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 KFY00205.1 - 2.4 8.7 4.6 17 5.9 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 KFY00205.1 - 5.5 7.1 10.8 0.27 11.3 1.7 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPPII_N PF12583.8 KFY00205.1 - 9.1 6.9 11.5 5.8 7.5 7.9 2.3 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal IATP PF04568.12 KFY00206.1 - 3.7e-22 78.6 1.4 4.2e-22 78.4 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 14-3-3 PF00244.20 KFY00207.1 - 1.8e-107 357.9 6.6 2.2e-107 357.6 6.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KFY00207.1 - 0.083 11.3 4.3 0.14 10.5 4.3 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TPR_19 PF14559.6 KFY00207.1 - 0.26 11.8 3.4 0.73 10.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DSPn PF14671.6 KFY00208.1 - 1.8e-42 145.1 0.0 1.8e-40 138.6 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFY00208.1 - 2.9e-15 56.3 0.0 6.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFY00208.1 - 1.2e-05 25.0 0.4 2.2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pcc1 PF09341.10 KFY00209.1 - 4.1e-31 106.9 0.9 5e-31 106.7 0.9 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Thioredoxin PF00085.20 KFY00210.1 - 3.1e-63 210.2 1.3 6.1e-30 103.3 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFY00210.1 - 6.1e-45 153.4 1.4 4.6e-32 111.4 0.5 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 KFY00210.1 - 1.2e-08 34.4 1.5 1.2e-08 34.4 1.5 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 KFY00210.1 - 1.9e-08 34.7 0.4 0.004 17.6 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFY00210.1 - 3.3e-08 33.2 0.3 0.0053 16.2 0.0 3.0 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFY00210.1 - 3.5e-08 33.7 0.0 0.011 16.0 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KFY00210.1 - 1.3e-07 31.7 0.1 0.078 13.2 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFY00210.1 - 3.4e-06 27.0 0.6 0.016 15.1 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KFY00210.1 - 0.00037 20.2 2.2 0.53 10.0 0.0 3.2 3 0 0 3 3 3 2 Redoxin YtxH PF12732.7 KFY00210.1 - 0.0061 17.1 3.7 0.0061 17.1 3.7 2.9 3 0 0 3 3 2 1 YtxH-like protein Apolipoprotein PF01442.18 KFY00210.1 - 0.13 12.2 5.9 0.098 12.5 3.8 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KFY00210.1 - 3.9 8.2 11.1 0.089 13.4 3.9 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Rad4 PF03835.15 KFY00221.1 - 2.2e-14 53.4 1.1 4.5e-14 52.4 1.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KFY00221.1 - 8.1e-13 48.8 3.6 1.7e-12 47.8 3.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 KFY00221.1 - 0.071 12.8 1.1 1.5 8.6 0.4 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Totivirus_coat PF05518.11 KFY00221.1 - 0.3 9.1 1.1 0.46 8.5 1.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Memo PF01875.17 KFY00222.1 - 7e-68 228.7 0.0 1e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.32 KFY00222.1 - 2.9e-08 34.2 14.0 2.5 9.1 0.0 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00222.1 - 7.7e-07 29.3 0.4 0.13 12.6 0.0 6.0 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFY00222.1 - 0.073 13.0 0.1 0.93 9.5 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 KFY00222.1 - 0.11 12.0 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) C1_4 PF07975.12 KFY00223.1 - 0.12 12.6 5.6 9.9 6.5 0.0 2.6 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C3HC4_3 PF13920.6 KFY00223.1 - 0.98 9.3 10.7 0.18 11.7 6.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KFY00223.1 - 1.5 9.0 9.5 0.21 11.8 4.5 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 KFY00223.1 - 3.8 7.7 12.7 0.75 10.0 2.9 2.5 2 0 0 2 2 2 0 B-box zinc finger zf-piccolo PF05715.13 KFY00223.1 - 3.9 7.7 14.4 1.3 9.3 7.8 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger Syntaxin PF00804.25 KFY00224.1 - 2.4e-21 76.3 15.8 1.1e-20 74.2 15.8 1.9 1 1 0 1 1 1 1 Syntaxin Use1 PF09753.9 KFY00224.1 - 1.9e-07 31.1 9.8 2.9e-07 30.5 9.8 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KFY00224.1 - 4.9e-07 29.7 10.3 4.9e-07 29.7 10.3 3.0 2 1 0 2 2 2 1 SNARE domain Vac_Fusion PF02346.16 KFY00224.1 - 0.0004 20.0 0.4 0.055 13.1 0.0 2.8 2 0 0 2 2 2 1 Chordopoxvirus multifunctional envelope protein A27 ODV-E18 PF10717.9 KFY00224.1 - 0.0013 18.5 0.2 0.0031 17.3 0.2 1.6 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 SecG PF03840.14 KFY00224.1 - 0.0089 16.1 0.4 0.03 14.4 0.4 1.9 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF5385 PF17359.2 KFY00224.1 - 0.01 15.4 0.9 0.01 15.4 0.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) T2SSF PF00482.23 KFY00224.1 - 0.014 15.3 3.2 0.11 12.5 2.7 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F FUSC PF04632.12 KFY00224.1 - 0.018 13.6 3.3 0.038 12.6 3.3 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1676 PF07898.13 KFY00224.1 - 0.026 14.6 0.5 0.052 13.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2207 PF09972.9 KFY00224.1 - 0.064 12.0 2.7 0.19 10.5 2.6 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 KFY00224.1 - 0.08 13.2 0.3 0.22 11.8 0.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF1772 PF08592.11 KFY00224.1 - 0.085 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4330 PF14221.6 KFY00224.1 - 0.1 12.8 0.4 0.1 12.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) ECSCR PF15820.5 KFY00224.1 - 0.12 12.2 1.0 0.56 10.1 0.4 2.1 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SID-1_RNA_chan PF13965.6 KFY00224.1 - 0.13 10.7 0.6 0.16 10.4 0.1 1.3 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 SP_C-Propep PF08999.10 KFY00224.1 - 0.13 12.0 2.1 0.28 11.0 2.1 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.6 KFY00224.1 - 0.16 12.9 0.0 0.67 10.9 0.0 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PBP1_TM PF14812.6 KFY00224.1 - 0.26 11.7 2.3 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chordopox_A33R PF05966.12 KFY00224.1 - 0.55 9.5 2.8 0.56 9.5 0.5 1.9 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Spectrin PF00435.21 KFY00224.1 - 0.69 10.4 11.7 1.5 9.4 0.5 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF4094 PF13334.6 KFY00224.1 - 1 9.8 7.9 1.7 9.1 3.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.11 KFY00224.1 - 1.5 8.3 8.9 0.22 11.0 0.4 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF1319 PF07028.11 KFY00224.1 - 1.9 8.7 9.4 1.6 9.0 0.9 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1319) RIFIN PF02009.16 KFY00224.1 - 10 5.9 12.6 33 4.2 12.6 1.9 1 1 0 1 1 1 0 Rifin Homeodomain PF00046.29 KFY00225.1 - 9.7e-06 25.3 0.6 1.7e-05 24.5 0.6 1.4 1 0 0 1 1 1 1 Homeodomain AsmA_1 PF13109.6 KFY00225.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region Phosducin PF02114.16 KFY00226.1 - 4.7e-13 48.7 0.0 5.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Phosducin NUFIP1 PF10453.9 KFY00226.1 - 0.025 14.4 3.2 0.043 13.7 3.2 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Exo_endo_phos PF03372.23 KFY00227.1 - 0.0038 16.8 0.1 0.011 15.2 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asp4 PF16996.5 KFY00228.1 - 7.5 6.4 6.4 12 5.7 5.0 2.2 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 PTPLA PF04387.14 KFY00229.1 - 2.7e-55 186.6 11.1 2.7e-55 186.6 11.1 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Pardaxin PF07425.11 KFY00229.1 - 0.15 11.7 1.3 0.66 9.6 0.0 2.5 3 0 0 3 3 3 0 Pardaxin Adaptin_binding PF10199.9 KFY00230.1 - 2.2e-11 44.4 4.7 8e-11 42.6 3.1 2.5 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 FAD_binding_7 PF03441.14 KFY00231.1 - 3.9e-74 248.5 0.7 6.2e-74 247.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFY00231.1 - 1.3e-40 139.1 0.0 2.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Peptidase_S8 PF00082.22 KFY00242.1 - 2.4e-30 105.8 16.8 4.7e-30 104.9 16.8 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFY00242.1 - 1e-09 38.9 0.1 1.7e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 adh_short PF00106.25 KFY00243.1 - 9.6e-37 126.3 0.0 1.6e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00243.1 - 1.1e-20 74.2 0.0 2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFY00243.1 - 0.00017 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00243.1 - 0.0054 16.2 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFY00243.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 KFY00243.1 - 0.024 14.8 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT PF03061.22 KFY00243.1 - 0.072 13.5 0.2 0.37 11.2 0.1 2.2 2 0 0 2 2 2 0 Thioesterase superfamily DUF3520 PF12034.8 KFY00243.1 - 0.3 11.2 1.2 3.8 7.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) adh_short PF00106.25 KFY00270.1 - 0.0012 18.4 0.0 0.094 12.2 0.0 3.2 3 1 0 3 3 3 1 short chain dehydrogenase TMF_DNA_bd PF12329.8 KFY00270.1 - 0.014 15.4 0.2 0.026 14.5 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Imm_superinfect PF14373.6 KFY00270.1 - 0.016 15.1 0.4 0.039 13.9 0.4 1.7 1 0 0 1 1 1 0 Superinfection immunity protein Acetyltransf_8 PF13523.6 KFY00271.1 - 3.4e-48 163.0 0.1 5e-48 162.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFY00271.1 - 0.024 15.3 0.0 0.042 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.6 KFY00273.1 - 5.9e-07 29.6 0.0 7.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00273.1 - 9.5e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFY00273.1 - 0.00087 18.4 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KFY00273.1 - 0.0035 17.5 0.0 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFY00273.1 - 0.05 14.0 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KFY00273.1 - 0.061 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PsbX PF06596.11 KFY00278.1 - 0.038 14.0 1.9 0.11 12.6 1.9 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF4191 PF13829.6 KFY00278.1 - 0.17 11.2 1.1 0.2 11.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) LapA_dom PF06305.11 KFY00278.1 - 1.1 9.1 4.4 1.6 8.6 4.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FGFR3_TM PF18123.1 KFY00278.1 - 1.8 8.2 5.0 0.3 10.7 0.5 1.8 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain SPX PF03105.19 KFY00279.1 - 4.3 7.1 10.0 5.8 6.7 10.0 1.1 1 0 0 1 1 1 0 SPX domain Ctr PF04145.15 KFY00280.1 - 0.032 14.8 0.0 0.035 14.7 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family MFS_1 PF07690.16 KFY00283.1 - 5.2e-34 117.7 26.4 5.2e-34 117.7 26.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.13 KFY00283.1 - 0.067 13.8 0.5 23 5.7 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PXA PF02194.15 KFY00283.1 - 0.13 12.2 0.6 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 PXA domain DUF3827 PF12877.7 KFY00283.1 - 0.43 8.9 1.0 0.98 7.7 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Glyco_hydro_88 PF07470.13 KFY00284.1 - 1.1e-92 310.7 2.5 1.3e-92 310.5 2.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFY00284.1 - 0.062 11.8 0.3 0.26 9.7 0.3 1.8 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KFY00284.1 - 0.13 11.7 9.2 0.18 11.3 0.9 2.9 1 1 1 3 3 3 0 Glycosyl hydrolase family 76 CBM-like PF14683.6 KFY00285.1 - 4.8e-41 140.4 0.1 1.1e-40 139.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KFY00285.1 - 2.4e-10 40.1 0.1 7.8e-10 38.4 0.1 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KFY00285.1 - 5.4e-08 33.0 0.1 3.4e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFY00285.1 - 0.014 15.4 0.0 1.2 9.1 0.0 3.1 2 1 0 2 2 2 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 KFY00285.1 - 0.097 12.8 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) RhgB_N PF09284.10 KFY00285.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal fn3_3 PF14686.6 KFY00286.1 - 3.1e-27 94.2 0.5 7e-27 93.0 0.5 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KFY00286.1 - 1.2e-25 90.2 0.1 2.3e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III UCH_1 PF13423.6 KFY00291.1 - 9.5e-42 143.7 0.3 1.4e-41 143.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.27 KFY00292.1 - 2e-41 141.7 0.0 3.9e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFY00292.1 - 1.5e-28 99.3 0.0 5.8e-28 97.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFY00292.1 - 2.8e-06 27.6 0.4 6.4e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFY00292.1 - 0.00056 20.0 0.1 0.0033 17.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 KFY00292.1 - 3.5 6.4 11.6 5.5 5.7 11.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ran-binding PF05508.11 KFY00293.1 - 4.7e-114 380.6 0.0 6.2e-114 380.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein TRAUB PF08164.12 KFY00294.1 - 1.6e-28 99.0 0.0 1.6e-28 99.0 0.0 3.0 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KFY00294.1 - 2.2e-26 93.2 6.0 2.2e-26 93.2 6.0 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor DUF5051 PF16473.5 KFY00294.1 - 0.04 13.9 1.8 0.041 13.9 0.5 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like ParA PF10609.9 KFY00295.1 - 7.4e-94 313.8 0.0 8.7e-94 313.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFY00295.1 - 1.5e-12 47.7 0.0 6.4e-10 39.2 0.0 2.8 3 1 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFY00295.1 - 4.2e-09 36.6 0.2 2.2e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFY00295.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFY00295.1 - 0.0005 19.3 0.9 0.016 14.4 0.5 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KFY00295.1 - 0.001 18.7 0.2 0.0028 17.3 0.0 1.8 3 0 0 3 3 3 1 AAA domain Fer4_NifH PF00142.18 KFY00295.1 - 0.024 14.1 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KFY00295.1 - 0.034 13.9 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 KFY00295.1 - 0.2 11.1 0.2 1.1 8.6 0.1 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ PH_10 PF15411.6 KFY00310.1 - 4e-27 94.9 0.1 1.8e-26 92.8 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.6 KFY00310.1 - 0.00011 22.4 5.3 0.0002 21.6 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFY00310.1 - 0.00044 20.0 4.8 0.0008 19.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY00310.1 - 0.0015 18.5 5.6 0.0025 17.7 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFY00310.1 - 0.0026 17.3 3.1 0.005 16.4 3.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFY00310.1 - 0.0057 16.9 3.0 0.014 15.7 3.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFY00310.1 - 0.0072 16.2 2.0 0.015 15.2 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY00310.1 - 0.015 15.2 4.6 0.027 14.3 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 KFY00310.1 - 0.032 14.7 0.0 0.083 13.4 0.0 1.7 1 0 0 1 1 1 0 PH domain zf-RING_11 PF17123.5 KFY00310.1 - 0.086 12.6 2.8 0.18 11.6 2.8 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 KFY00310.1 - 0.17 12.2 4.8 0.33 11.3 4.8 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 KFY00310.1 - 0.73 9.7 3.3 1.4 8.8 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KFY00310.1 - 1.8 8.7 5.5 4.7 7.3 5.5 1.7 1 1 0 1 1 1 0 Zinc-finger O-FucT PF10250.9 KFY00316.1 - 5.5e-07 29.6 0.0 6.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ATP-synt_C PF00137.21 KFY00334.1 - 8e-12 45.3 16.5 2e-11 44.0 16.5 1.7 1 1 0 1 1 1 1 ATP synthase subunit C Fungal_trans PF04082.18 KFY00335.1 - 5e-07 29.0 4.1 7.6e-07 28.4 4.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AadA_C PF18280.1 KFY00335.1 - 0.021 15.0 0.1 0.73 10.0 0.0 2.3 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain Sugar_tr PF00083.24 KFY00336.1 - 1.3e-88 297.9 22.6 1.5e-88 297.6 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00336.1 - 4.6e-17 62.0 34.9 6e-12 45.2 18.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFY00336.1 - 0.003 16.5 4.2 0.003 16.5 4.2 1.8 2 0 0 2 2 2 1 MFS_1 like family Alpha-amylase PF00128.24 KFY00337.1 - 7.3e-112 374.3 0.0 1.3e-111 373.5 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFY00337.1 - 2.1e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFY00337.1 - 0.013 14.6 0.1 0.066 12.3 0.0 1.9 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_49N PF17433.2 KFY00338.1 - 9.8e-62 207.9 1.1 2.3e-61 206.7 1.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 KFY00338.1 - 3.6e-26 91.5 1.2 1e-25 90.0 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 IPU_b_solenoid PF18783.1 KFY00338.1 - 4.3e-23 81.0 1.5 1.2e-22 79.6 1.5 1.8 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 KFY00338.1 - 1.7e-15 57.0 1.3 9.5e-15 54.6 1.4 2.3 2 0 0 2 2 2 1 Beta solenoid repeat from Dextranase Glyco_hydro_28 PF00295.17 KFY00338.1 - 0.0008 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_35 PF01301.19 KFY00339.1 - 2.2e-83 280.5 1.3 3.4e-83 279.9 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFY00339.1 - 1.1e-60 203.1 4.0 3.6e-33 114.5 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KFY00339.1 - 9.5e-55 185.2 0.0 1.6e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KFY00339.1 - 3.1e-24 84.4 0.1 6e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KFY00339.1 - 0.0012 18.3 0.5 0.0031 17.0 0.4 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_31 PF01055.26 KFY00340.1 - 3.9e-157 524.0 0.2 4.8e-157 523.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFY00340.1 - 3e-40 137.0 0.1 5.5e-40 136.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFY00340.1 - 4.6e-14 52.5 5.1 9e-14 51.5 0.8 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 KFY00340.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) CUE PF02845.16 KFY00351.1 - 2.7e-11 42.9 0.0 5.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 KFY00351.1 - 0.00068 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF3697 PF12478.8 KFY00351.1 - 0.029 14.5 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 DUF1296 PF06972.11 KFY00351.1 - 0.055 13.6 0.1 0.25 11.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1296) UBA_4 PF14555.6 KFY00351.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Ras PF00071.22 KFY00362.1 - 1.3e-54 184.1 0.0 1.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY00362.1 - 3.8e-22 78.7 0.0 5.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY00362.1 - 4.5e-09 36.0 0.0 9e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFY00362.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFY00362.1 - 0.0012 18.1 0.0 0.0036 16.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 KFY00362.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFY00362.1 - 0.047 13.8 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KFY00362.1 - 0.19 12.3 0.0 0.29 11.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter CWC25 PF12542.8 KFY00363.1 - 1.9e-25 89.7 1.8 1.9e-25 89.7 1.8 3.5 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFY00363.1 - 2.2e-13 50.1 8.9 2.2e-13 50.1 8.9 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR SelP_N PF04592.14 KFY00363.1 - 6.9 6.0 10.7 18 4.7 10.7 1.8 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PCI PF01399.27 KFY00364.1 - 4e-19 69.1 2.1 7.9e-19 68.1 0.1 2.4 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KFY00364.1 - 0.0026 17.7 0.4 0.61 10.3 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFY00364.1 - 0.0042 16.7 0.6 0.015 15.0 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 KFY00364.1 - 0.0075 16.3 2.8 0.07 13.3 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFY00364.1 - 0.014 15.7 0.1 1.6 9.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFY00364.1 - 0.021 14.6 1.9 0.1 12.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KFY00364.1 - 0.042 13.9 1.1 0.13 12.4 0.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KFY00364.1 - 0.12 13.3 0.0 26 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00364.1 - 4.8 7.6 8.1 2.1 8.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PriX PF18689.1 KFY00364.1 - 6.1 7.2 6.8 14 6.1 0.3 3.6 2 1 0 3 3 3 0 Primase X 2OG-FeII_Oxy_3 PF13640.6 KFY00366.1 - 4.8e-06 27.4 0.0 1.1e-05 26.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ISK_Channel PF02060.15 KFY00367.1 - 0.12 12.1 0.0 1.2e+02 2.4 0.0 4.1 4 0 0 4 4 4 0 Slow voltage-gated potassium channel Ank_2 PF12796.7 KFY00368.1 - 1.8e-76 252.8 0.0 1.1e-13 51.5 0.0 7.6 3 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY00368.1 - 2.2e-51 171.6 0.0 5.8e-08 33.1 0.0 9.0 5 3 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY00368.1 - 1.5e-49 160.2 0.8 0.0049 17.3 0.0 13.6 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 KFY00368.1 - 9.6e-46 152.3 11.1 0.00027 21.2 0.1 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KFY00368.1 - 8.2e-40 134.3 7.1 2.1e-05 24.7 0.0 11.7 2 2 11 13 13 13 11 Ankyrin repeats (many copies) DUF676 PF05057.14 KFY00368.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFY00368.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 KFY00368.1 - 0.0075 16.1 0.0 0.29 11.0 0.0 3.0 3 0 0 3 3 3 1 Serine hydrolase Abhydrolase_6 PF12697.7 KFY00368.1 - 0.011 16.3 0.0 0.041 14.5 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFY00368.1 - 0.047 13.3 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 KFY00368.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FHA PF00498.26 KFY00369.1 - 1.1e-16 61.0 0.1 3.2e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFY00369.1 - 0.00044 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Uds1 PF15456.6 KFY00369.1 - 0.0033 17.6 5.6 0.0033 17.6 5.6 3.1 2 1 1 3 3 3 1 Up-regulated During Septation Med21 PF11221.8 KFY00369.1 - 0.0052 17.0 7.2 0.0052 17.0 7.2 3.8 4 1 0 4 4 4 1 Subunit 21 of Mediator complex YhfZ_C PF14503.6 KFY00369.1 - 0.09 12.3 0.0 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 YhfZ C-terminal domain TUDOR PF00567.24 KFY00369.1 - 0.17 11.9 0.6 4 7.5 0.0 2.7 2 0 0 2 2 2 0 Tudor domain Med9 PF07544.13 KFY00369.1 - 0.24 11.5 5.6 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 KFY00369.1 - 2 7.2 4.9 1.5 7.7 0.2 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein MCU PF04678.13 KFY00369.1 - 2.7 8.0 8.4 6.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter EMP24_GP25L PF01105.24 KFY00369.1 - 9.8 6.1 7.3 2.8 7.9 0.3 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SIR2 PF02146.17 KFY00370.1 - 9e-56 188.6 0.0 1.3e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KFY00370.1 - 0.19 11.5 0.0 0.49 10.1 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Complex1_LYR PF05347.15 KFY00374.1 - 1.1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UQ_con PF00179.26 KFY00375.1 - 3.8e-18 65.5 0.0 3.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFY00375.1 - 0.02 15.2 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain CENP-T_C PF15511.6 KFY00375.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DCB PF16213.5 KFY00376.1 - 3e-46 157.3 6.2 7.4e-44 149.5 3.5 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFY00376.1 - 1.3e-44 151.9 0.7 1.3e-44 151.9 0.7 2.6 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KFY00376.1 - 5.9e-27 94.2 5.3 1.8e-22 79.3 2.4 3.2 3 0 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KFY00376.1 - 0.0012 18.6 0.0 0.065 13.1 0.0 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) DRIM PF07539.12 KFY00376.1 - 0.02 13.2 0.1 0.02 13.2 0.1 3.0 5 0 0 5 5 5 0 Down-regulated in metastasis Band_7 PF01145.25 KFY00377.1 - 4.1e-31 108.4 0.4 7.9e-31 107.4 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFY00377.1 - 3.2e-24 84.7 2.4 8.6e-24 83.4 2.4 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 KFY00377.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pox_A11 PF05061.13 KFY00377.1 - 0.12 11.6 1.3 0.27 10.5 1.3 1.6 1 1 0 1 1 1 0 Poxvirus A11 Protein zf-U1 PF06220.12 KFY00378.1 - 0.00031 20.4 0.5 0.00063 19.5 0.5 1.5 1 0 0 1 1 1 1 U1 zinc finger MARVEL PF01284.23 KFY00379.1 - 2.7e-07 30.7 16.1 5.2e-06 26.6 10.9 2.1 1 1 0 2 2 2 2 Membrane-associating domain VIT1 PF01988.19 KFY00379.1 - 0.0089 15.9 1.8 0.012 15.5 1.5 1.3 1 1 0 1 1 1 1 VIT family ABC2_membrane_4 PF12730.7 KFY00379.1 - 0.074 13.0 6.7 0.029 14.4 2.1 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Tetraspanin PF00335.20 KFY00379.1 - 5.6 6.6 9.6 2.8 7.6 5.8 1.9 1 1 1 2 2 2 0 Tetraspanin family Amidoligase_2 PF12224.8 KFY00380.1 - 1.3e-23 84.0 0.0 2e-23 83.4 0.0 1.4 1 1 0 1 1 1 1 Putative amidoligase enzyme Gtr1_RagA PF04670.12 KFY00380.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3328 PF11807.8 KFY00383.1 - 9.5e-34 117.1 0.2 1.2e-33 116.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Gly_transf_sug PF04488.15 KFY00391.1 - 4e-13 49.8 0.1 7.2e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GN3L_Grn1 PF08701.11 KFY00392.1 - 7.9e-23 80.4 14.4 7.9e-23 80.4 14.4 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase Dynamin_N PF00350.23 KFY00392.1 - 0.0042 17.1 3.5 0.0094 16.0 3.5 1.7 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 KFY00392.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFY00392.1 - 0.0087 16.1 0.2 0.017 15.2 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY00392.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Nuc_deoxyri_tr2 PF15891.5 KFY00392.1 - 0.058 13.7 0.9 0.52 10.6 0.0 2.4 2 1 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Arf PF00025.21 KFY00392.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family BUD22 PF09073.10 KFY00392.1 - 0.98 8.7 22.4 1.4 8.2 22.4 1.1 1 0 0 1 1 1 0 BUD22 HAD_2 PF13419.6 KFY00393.1 - 4.3e-18 66.0 0.0 7.6e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY00393.1 - 4.3e-09 37.0 0.0 9.3e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY00393.1 - 1.6e-06 28.1 0.1 2.6e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.26 KFY00393.1 - 0.004 17.1 1.5 0.017 15.1 0.5 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HAD PF12710.7 KFY00393.1 - 0.013 16.0 0.0 0.025 15.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 KFY00394.1 - 7e-28 97.4 0.3 1e-27 96.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00394.1 - 5.4e-24 85.0 0.2 6.6e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00394.1 - 7.5e-08 32.5 0.4 9.7e-08 32.1 0.4 1.2 1 0 0 1 1 1 1 KR domain Aldedh PF00171.22 KFY00396.1 - 1.1e-106 357.1 0.1 1.4e-106 356.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeodomain PF00046.29 KFY00397.1 - 1.8e-13 50.1 1.5 4e-13 49.0 1.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFY00397.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain SUR7 PF06687.12 KFY00401.1 - 1e-15 58.0 7.7 1.8e-14 53.9 8.6 1.9 1 1 1 2 2 2 1 SUR7/PalI family COX2_TM PF02790.15 KFY00401.1 - 0.039 14.1 0.9 0.039 14.1 0.9 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF872 PF05915.12 KFY00401.1 - 0.25 11.5 2.1 0.93 9.7 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TMEM51 PF15345.6 KFY00401.1 - 0.25 11.1 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 RCR PF12273.8 KFY00401.1 - 0.49 11.1 0.1 0.49 11.1 0.1 2.0 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red MRAP PF15183.6 KFY00401.1 - 0.52 10.3 0.1 0.52 10.3 0.1 3.0 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF805 PF05656.14 KFY00401.1 - 0.72 10.3 4.7 0.38 11.2 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ERGIC_N PF13850.6 KFY00401.1 - 1.3 9.4 3.3 3.7 8.0 0.0 2.6 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2663 PF10864.8 KFY00401.1 - 2.6 8.5 4.4 0.49 10.8 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) zf-LITAF-like PF10601.9 KFY00401.1 - 4.1 7.7 0.0 4.1 7.7 0.0 3.0 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain TPR_10 PF13374.6 KFY00402.1 - 6.1e-113 366.1 19.8 3.8e-10 39.3 0.0 11.3 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFY00402.1 - 4.3e-86 283.2 15.9 1.1e-13 51.2 0.1 10.5 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY00402.1 - 2.5e-19 69.8 31.6 1.2e-06 28.2 7.8 6.0 1 1 4 5 5 5 5 MalT-like TPR region TPR_4 PF07721.14 KFY00402.1 - 4.7e-17 60.8 0.1 3.9 8.4 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFY00402.1 - 1.3e-13 50.1 2.0 4.9 7.1 0.1 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00402.1 - 1.3e-13 49.9 1.1 2 8.7 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFY00402.1 - 5.7e-12 45.1 2.9 0.35 11.4 0.0 10.1 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY00402.1 - 1.7e-08 33.9 11.6 0.82 9.8 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFY00402.1 - 6.2e-06 26.6 9.6 0.029 14.9 0.0 6.3 3 3 6 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00402.1 - 4.7e-05 23.9 0.3 45 4.8 0.0 6.7 6 2 0 7 7 7 0 Tetratricopeptide repeat DUF4713 PF15831.5 KFY00402.1 - 0.00014 22.3 0.5 31 5.1 0.0 5.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4713) Imm49 PF15575.6 KFY00402.1 - 0.00026 20.8 0.3 1.4 8.7 0.0 4.3 1 1 3 5 5 5 1 Immunity protein 49 TadF PF16964.5 KFY00402.1 - 0.00067 19.5 1.9 20 4.9 0.0 4.5 4 1 0 4 4 4 0 Putative tight adherence pilin protein F Enolase_C PF00113.22 KFY00402.1 - 0.0012 18.2 2.4 7.8 5.6 0.0 5.2 2 1 3 6 6 6 0 Enolase, C-terminal TIM barrel domain DUF3481 PF11980.8 KFY00402.1 - 0.0014 18.3 0.1 37 4.1 0.0 4.8 4 1 1 5 5 4 0 C-terminal domain of neuropilin glycoprotein Guanylate_cyc_2 PF09778.9 KFY00402.1 - 0.0039 16.6 5.1 3.9 6.8 0.2 5.0 3 1 3 6 6 6 1 Guanylylate cyclase Herpes_UL33 PF03581.13 KFY00402.1 - 0.0046 17.3 9.1 17 5.9 0.1 6.4 6 3 2 8 8 6 0 Herpesvirus UL33-like protein AviRa PF11599.8 KFY00402.1 - 0.0058 16.1 9.3 4.4 6.7 0.1 4.2 2 1 1 4 4 4 2 RRNA methyltransferase AviRa TPR_8 PF13181.6 KFY00402.1 - 0.019 15.1 9.6 30 5.2 0.0 7.6 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF3305 PF11749.8 KFY00402.1 - 0.034 14.3 0.0 0.67 10.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3305) MGDG_synth PF06925.11 KFY00402.1 - 0.093 12.8 0.1 5.4 7.1 0.0 2.9 1 1 1 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase TPR_15 PF13429.6 KFY00402.1 - 0.11 11.7 4.5 1.1 8.4 0.3 4.3 3 1 3 7 7 6 0 Tetratricopeptide repeat L27 PF02828.16 KFY00402.1 - 0.13 12.0 13.6 72 3.3 0.0 7.3 8 0 0 8 8 8 0 L27 domain PreAtp-grasp PF18604.1 KFY00402.1 - 0.14 11.8 3.5 32 4.2 0.0 5.3 2 2 2 6 6 6 0 Pre ATP-grasp domain Terminase_2 PF03592.16 KFY00402.1 - 0.16 12.4 7.8 15 6.0 0.1 4.5 1 1 3 4 4 4 0 Terminase small subunit DciA PF05258.12 KFY00402.1 - 0.25 11.8 4.3 2.1e+02 2.4 0.0 5.5 7 0 0 7 7 6 0 Dna[CI] antecedent, DciA DUF2526 PF10735.9 KFY00402.1 - 0.44 10.8 14.9 3.8 7.8 0.1 6.3 4 3 4 8 8 7 0 Protein of unknown function (DUF2526) TPR_20 PF14561.6 KFY00402.1 - 0.66 10.3 10.5 20 5.6 0.0 5.6 2 2 4 7 7 7 0 Tetratricopeptide repeat Corona_S2 PF01601.16 KFY00402.1 - 2.5 6.5 8.6 3.2 6.1 0.0 3.8 1 1 4 5 5 5 0 Coronavirus S2 glycoprotein F-box-like PF12937.7 KFY00403.1 - 0.0013 18.5 1.8 0.0098 15.8 0.0 3.1 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 KFY00403.1 - 0.023 14.6 0.1 6.3 6.8 0.0 2.9 2 0 0 2 2 2 0 F-box domain zf-CCCH PF00642.24 KFY00423.1 - 6.3e-21 73.8 25.3 2.5e-07 30.4 0.4 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFY00423.1 - 1.3e-10 41.0 26.6 2.6e-05 24.1 0.4 5.6 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KFY00423.1 - 6.9e-08 33.2 20.0 0.029 15.1 0.0 5.1 1 1 4 5 5 5 3 Torus domain zf-CCCH_4 PF18044.1 KFY00423.1 - 1.9e-06 27.5 1.7 0.002 17.9 0.8 5.0 5 1 0 5 5 5 3 CCCH-type zinc finger zf-C3H1 PF10650.9 KFY00423.1 - 0.00066 19.3 2.6 0.13 12.0 0.0 3.5 3 0 0 3 3 3 1 Putative zinc-finger domain zf-CCCH_3 PF15663.5 KFY00423.1 - 0.0038 17.4 1.6 0.0038 17.4 1.6 3.5 1 1 2 3 3 3 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFY00423.1 - 0.015 15.7 1.5 0.015 15.7 1.5 4.3 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger UPF0254 PF06787.11 KFY00425.1 - 0.11 12.2 0.5 0.15 11.8 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Sporozoite_P67 PF05642.11 KFY00425.1 - 7.3 4.5 8.1 7.7 4.5 8.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YbjQ_1 PF01906.17 KFY00427.1 - 6.7e-33 113.4 0.6 8e-33 113.2 0.6 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Mt_ATP-synt_B PF05405.14 KFY00428.1 - 4.6e-50 169.4 5.1 5.7e-50 169.1 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.25 KFY00428.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Adenyl_cycl_N PF12633.7 KFY00428.1 - 0.039 13.8 0.2 0.075 12.9 0.2 1.6 1 1 0 1 1 1 0 Adenylate cyclase NT domain CBF PF03914.17 KFY00429.1 - 3.8e-35 121.4 1.7 1.6e-34 119.4 0.1 2.9 4 0 0 4 4 4 1 CBF/Mak21 family DUF5558 PF17713.1 KFY00436.1 - 0.05 14.0 0.3 0.05 14.0 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5558) DUF2868 PF11067.8 KFY00436.1 - 0.66 9.4 3.5 0.93 8.9 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) RNase_T PF00929.24 KFY00437.1 - 3.5e-09 37.4 0.0 1.6e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFY00437.1 - 0.03 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease Yippee-Mis18 PF03226.14 KFY00438.1 - 0.00011 22.4 0.3 0.0002 21.5 0.3 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BLOC1_2 PF10046.9 KFY00438.1 - 0.21 11.9 2.3 1.7 9.0 0.4 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ofd1_CTDD PF10637.9 KFY00440.1 - 1.9e-42 145.4 0.0 2.6e-39 135.1 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFY00440.1 - 1.7e-25 89.5 0.0 3.8e-25 88.4 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFY00440.1 - 9.2e-14 52.1 0.0 1.6e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.14 KFY00441.1 - 2.9e-07 30.7 9.6 6.3e-05 23.2 0.3 3.3 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFY00441.1 - 0.00026 20.6 3.5 0.13 12.0 0.1 2.8 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.13 KFY00441.1 - 0.0051 16.5 5.7 1.5 8.6 0.1 3.4 3 0 0 3 3 3 2 CSL zinc finger zf_C2H2_13 PF18508.1 KFY00441.1 - 0.029 14.0 0.3 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Zinc finger domain PknG_rubred PF16919.5 KFY00441.1 - 0.034 14.3 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain MqsA_antitoxin PF15731.5 KFY00441.1 - 0.056 13.5 0.3 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF2321 PF10083.9 KFY00441.1 - 0.073 12.7 2.4 1.4 8.5 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 KFY00441.1 - 0.074 13.0 12.2 0.076 12.9 0.2 3.7 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KFY00441.1 - 3.2 7.6 10.0 1.4 8.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KFY00441.1 - 5.4 7.1 12.5 1.3 9.1 0.1 3.2 2 2 0 3 3 3 0 Double zinc ribbon DUF4472 PF14739.6 KFY00442.1 - 0.24 12.1 0.1 0.24 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Co_AT_N PF12557.8 KFY00442.1 - 0.56 10.2 2.8 1.5 8.8 2.8 1.8 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Pkinase PF00069.25 KFY00444.1 - 2.7e-59 200.7 0.0 6.7e-59 199.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00444.1 - 3.7e-29 101.8 0.0 8.5e-29 100.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFY00444.1 - 5.1e-10 39.5 0.1 8.3e-09 35.7 0.0 2.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFY00444.1 - 0.0031 17.8 0.0 0.0084 16.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KFY00444.1 - 0.0044 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltranf_PUA PF13636.6 KFY00444.1 - 0.064 13.3 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF Kinase-like PF14531.6 KFY00444.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like p450 PF00067.22 KFY00445.1 - 1e-49 169.6 0.0 1.6e-49 168.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Patatin PF01734.22 KFY00449.1 - 4.6e-20 72.7 0.1 1.9e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase CENP-F_leu_zip PF10473.9 KFY00449.1 - 0.21 11.6 5.0 0.58 10.2 5.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 KFY00450.1 - 0.16 12.3 4.2 0.32 11.3 4.3 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 HMMR_N PF15905.5 KFY00450.1 - 0.21 11.0 4.5 0.85 9.0 4.3 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Mt_ATP-synt_D PF05873.12 KFY00450.1 - 0.45 10.4 4.7 3.6 7.4 0.6 2.1 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Ntox1 PF15500.6 KFY00451.1 - 0.068 13.5 0.1 0.2 12.0 0.1 1.7 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Skp1_POZ PF03931.15 KFY00452.1 - 9.2e-07 29.0 0.1 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ank_2 PF12796.7 KFY00453.1 - 1.2e-07 32.2 0.0 9.2e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY00453.1 - 3e-06 27.7 0.0 0.97 10.1 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY00453.1 - 7.6e-06 26.1 0.1 0.9 10.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFY00453.1 - 0.00035 20.8 0.0 0.29 11.8 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KFY00453.1 - 0.007 16.7 0.0 5.7 7.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TPR_1 PF00515.28 KFY00454.1 - 3.9e-08 32.8 3.8 0.038 13.8 1.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00454.1 - 4.8e-06 26.3 8.3 0.24 11.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00454.1 - 0.018 15.2 4.0 0.43 10.9 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00454.1 - 0.042 14.5 10.3 1.6 9.5 4.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MatE PF01554.18 KFY00456.1 - 5.6e-08 32.6 1.2 7.1e-08 32.3 1.2 1.0 1 0 0 1 1 1 1 MatE SIR2 PF02146.17 KFY00457.1 - 3.5e-23 82.4 0.0 1.1e-22 80.9 0.0 1.9 1 1 0 1 1 1 1 Sir2 family SET PF00856.28 KFY00457.1 - 2.5e-08 34.5 0.1 1.1e-07 32.4 0.1 2.3 1 1 0 1 1 1 1 SET domain SIR2_2 PF13289.6 KFY00457.1 - 0.0032 17.6 0.1 0.042 14.0 0.0 2.7 3 0 0 3 3 3 1 SIR2-like domain zinc_ribbon_10 PF10058.9 KFY00457.1 - 0.03 14.0 0.0 0.14 11.9 0.0 2.2 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein F-box PF00646.33 KFY00458.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain Orn_Arg_deC_N PF02784.16 KFY00459.1 - 7.4e-67 225.3 0.0 9.2e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFY00459.1 - 4.2e-15 55.8 0.0 4.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cu_amine_oxid PF01179.20 KFY00460.1 - 3.6e-153 510.3 0.0 4.6e-153 510.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFY00460.1 - 5.1e-20 71.8 0.0 1.1e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFY00460.1 - 2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain BCA_ABC_TP_C PF12399.8 KFY00460.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Vps54_N PF10475.9 KFY00466.1 - 2.4e-06 27.1 1.7 6.6e-06 25.6 0.2 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex FliJ PF02050.16 KFY00466.1 - 0.041 14.1 0.6 0.041 14.1 0.6 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4055 PF13264.6 KFY00466.1 - 0.08 13.1 0.4 0.24 11.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) T3SS_needle_E PF08988.10 KFY00466.1 - 0.59 10.3 4.2 11 6.3 0.1 3.4 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle MCM PF00493.23 KFY00467.1 - 3.2e-105 350.2 0.3 1.2e-104 348.3 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFY00467.1 - 2.2e-34 118.0 0.4 4.5e-34 117.0 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFY00467.1 - 4.3e-31 107.2 0.8 9.9e-31 106.0 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFY00467.1 - 3.3e-15 56.5 0.2 7.5e-15 55.4 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFY00467.1 - 9.6e-08 31.7 0.1 6.2e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFY00467.1 - 8.8e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFY00467.1 - 0.00038 20.3 0.0 0.0015 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFY00467.1 - 0.0057 16.4 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 KFY00467.1 - 0.046 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFY00467.1 - 0.11 12.9 0.9 0.86 10.0 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF1048 PF06304.11 KFY00468.1 - 0.007 16.8 0.0 0.0081 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) DUF5100 PF17029.5 KFY00468.1 - 0.037 13.9 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) MFS_1 PF07690.16 KFY00474.1 - 4e-13 49.0 21.1 5.6e-13 48.5 21.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.19 KFY00475.1 - 1e-44 152.2 0.0 2.3e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TauD PF02668.16 KFY00475.1 - 1e-43 150.1 0.2 1.6e-43 149.5 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mo-co_dimer PF03404.16 KFY00475.1 - 2.4e-19 69.7 5.3 4.5e-19 68.8 4.1 2.1 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain WD40 PF00400.32 KFY00476.1 - 9.8e-25 86.4 19.4 9.8e-06 26.2 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KFY00476.1 - 2.1e-10 40.3 0.0 4.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KFY00476.1 - 1.9e-07 30.2 2.2 0.011 14.4 0.0 3.7 2 2 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 KFY00476.1 - 5.6e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KFY00476.1 - 8.8e-05 22.7 0.1 1.3 9.4 0.1 4.5 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KFY00476.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box Ge1_WD40 PF16529.5 KFY00476.1 - 0.17 10.8 0.0 10 4.9 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GPI-anchored PF10342.9 KFY00489.1 - 1.7e-07 31.9 0.0 2.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family adh_short PF00106.25 KFY00495.1 - 8.1e-18 64.6 0.4 3.3e-17 62.6 0.6 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFY00495.1 - 3.8e-10 40.0 0.1 6.9e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFY00495.1 - 1.3e-08 34.7 1.6 1.6e-08 34.4 0.3 1.7 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 KFY00496.1 - 4.1e-11 43.0 0.0 8.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY00496.1 - 8e-07 28.9 0.2 2.2e-06 27.5 0.2 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFY00496.1 - 0.0098 16.9 0.0 0.015 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HhH-GPD PF00730.25 KFY00497.1 - 4.2e-14 52.9 0.0 8.6e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CYYR1 PF10873.8 KFY00497.1 - 0.037 14.5 3.4 0.54 10.7 4.9 1.9 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TFIIF_alpha PF05793.12 KFY00497.1 - 6 5.3 6.5 8.7 4.8 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Anp1 PF03452.14 KFY00498.1 - 1.9e-104 348.8 0.0 2.3e-104 348.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 MFS_1 PF07690.16 KFY00500.1 - 2.8e-29 102.2 55.3 8.8e-29 100.5 53.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00500.1 - 1.9e-11 43.5 11.7 1.9e-11 43.5 11.7 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter PAN_3 PF08277.12 KFY00501.1 - 0.4 10.5 0.0 0.4 10.5 0.0 4.8 4 0 0 4 4 4 0 PAN-like domain Oxidored_FMN PF00724.20 KFY00502.1 - 4.6e-80 269.5 0.0 5.7e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KFY00502.1 - 0.0092 15.4 0.0 0.35 10.3 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel Fungal_trans_2 PF11951.8 KFY00503.1 - 8.4e-05 21.5 0.3 0.00027 19.9 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TMEM107 PF14995.6 KFY00503.1 - 1.4 9.4 3.7 6.9 7.1 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein MFS_1 PF07690.16 KFY00504.1 - 2e-14 53.3 22.1 2.5e-14 53.0 22.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00506.1 - 0.0033 16.4 1.3 0.0034 16.3 1.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.13 KFY00509.1 - 1.1e-20 74.4 0.0 1.4e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY00509.1 - 0.00013 22.7 2.8 0.00026 21.7 2.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY00509.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3336 PF11815.8 KFY00511.1 - 3.2e-33 114.4 0.1 9.6e-33 112.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFY00511.1 - 3.9e-23 82.7 0.1 1.6e-22 80.7 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase TAFH PF07531.14 KFY00511.1 - 0.1 12.7 1.0 1 9.5 0.1 2.9 3 0 0 3 3 3 0 NHR1 homology to TAF adh_short_C2 PF13561.6 KFY00534.1 - 2.2e-62 210.7 1.8 3.1e-62 210.2 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY00534.1 - 3.8e-50 170.1 1.2 5.4e-50 169.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY00534.1 - 6.5e-12 45.7 0.4 9.4e-12 45.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00534.1 - 1.2e-05 24.9 0.2 2.2e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 KFY00534.1 - 0.0043 17.0 0.3 0.02 14.9 0.2 2.1 2 1 0 2 2 2 1 PA domain Sacchrp_dh_NADP PF03435.18 KFY00534.1 - 0.049 13.9 0.2 0.27 11.5 0.1 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFY00534.1 - 0.05 12.7 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFY00534.1 - 0.18 11.1 0.2 0.6 9.5 0.2 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Lipase_GDSL_2 PF13472.6 KFY00538.1 - 1.8e-23 83.9 0.0 2.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY00538.1 - 8.8e-08 32.4 0.0 1.5e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFY00538.1 - 1.6e-07 31.7 0.0 9.2e-06 25.9 0.0 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Herpes_BTRF1 PF04682.12 KFY00538.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region 2-Hacid_dh_C PF02826.19 KFY00539.1 - 5.5e-36 123.6 0.0 2.6e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFY00539.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KFY00539.1 - 0.14 12.8 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFY00539.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ERG4_ERG24 PF01222.17 KFY00542.1 - 7.9e-146 486.2 20.3 1e-145 485.8 20.3 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MGC-24 PF05283.11 KFY00542.1 - 0.01 16.3 3.1 0.019 15.4 3.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_1 PF00232.18 KFY00543.1 - 1.4e-77 261.1 1.2 1.2e-75 254.7 1.2 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans_2 PF11951.8 KFY00543.1 - 7.5e-35 120.5 0.2 1.6e-34 119.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00543.1 - 5e-09 36.1 5.1 5e-09 36.1 5.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KFY00544.1 - 1.2e-46 159.5 0.0 1.8e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase GMC_oxred_N PF00732.19 KFY00545.1 - 7.4e-63 212.7 0.0 9.5e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY00545.1 - 1.1e-33 116.8 0.0 1.9e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFY00545.1 - 1.2e-05 24.6 1.3 0.022 13.9 1.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFY00545.1 - 4.4e-05 22.8 0.3 0.013 14.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 KFY00545.1 - 0.00062 18.9 0.7 0.0013 17.9 0.7 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFY00545.1 - 0.0028 17.9 0.5 0.0075 16.5 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY00545.1 - 0.072 12.3 0.5 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY00545.1 - 0.29 10.7 2.4 1.1 8.8 1.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY00545.1 - 0.68 8.6 2.3 0.44 9.2 0.7 1.4 2 0 0 2 2 2 0 HI0933-like protein TarH PF02203.15 KFY00546.1 - 0.19 11.7 4.7 0.14 12.1 0.7 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue B12D PF06522.11 KFY00546.1 - 0.59 10.0 2.1 3.3 7.6 0.9 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MIF PF01187.18 KFY00547.1 - 0.00036 20.8 0.0 0.00059 20.1 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) ELO PF01151.18 KFY00548.1 - 1.6e-79 267.0 8.7 1.9e-79 266.7 8.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_39 PF01229.17 KFY00548.1 - 0.068 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Gtr1_RagA PF04670.12 KFY00552.1 - 2.1e-68 230.2 0.1 2.4e-68 230.0 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KFY00552.1 - 0.0018 18.5 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY00552.1 - 0.0019 17.7 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 KFY00552.1 - 0.027 14.8 0.0 0.043 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KFY00552.1 - 0.039 14.1 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KFY00552.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.23 KFY00553.1 - 3.5e-72 242.9 2.4 4.9e-72 242.4 2.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY00553.1 - 2.1e-41 140.4 0.4 2.1e-41 140.4 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFY00553.1 - 1.7e-06 27.8 1.2 5e-06 26.3 1.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFY00553.1 - 0.023 14.6 0.9 0.37 10.7 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L50 PF10501.9 KFY00554.1 - 4.5e-15 55.7 0.0 7.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S ETRAMP PF09716.10 KFY00555.1 - 0.14 12.2 0.8 0.28 11.3 0.8 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DAHP_synth_1 PF00793.20 KFY00556.1 - 1.1e-96 323.0 0.2 4.8e-96 320.8 0.2 1.8 1 1 0 1 1 1 1 DAHP synthetase I family RNA_pol_Rpc4 PF05132.14 KFY00558.1 - 0.027 14.9 0.6 0.041 14.3 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pkinase PF00069.25 KFY00559.1 - 2e-60 204.4 0.0 2.8e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00559.1 - 1.1e-27 97.0 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY00559.1 - 0.00012 21.6 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFY00559.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF3621 PF12285.8 KFY00559.1 - 0.11 12.8 0.3 0.11 12.8 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) APH PF01636.23 KFY00559.1 - 0.15 11.9 6.3 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family eIF3_subunit PF08597.10 KFY00559.1 - 0.72 9.7 16.0 1 9.2 16.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4661 PF15576.6 KFY00559.1 - 2 8.3 4.9 3.4 7.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Methyltransf_28 PF02636.17 KFY00560.1 - 1.2e-81 274.2 0.0 1.6e-81 273.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase stn_TNFRSF12A PF12191.8 KFY00560.1 - 0.035 14.3 0.3 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain EHN PF06441.12 KFY00561.1 - 9.9e-36 122.4 1.1 8.6e-35 119.4 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFY00561.1 - 5.2e-12 46.0 0.0 9.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY00561.1 - 5.9e-06 27.0 3.3 1.7e-05 25.6 3.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.22 KFY00562.1 - 0.00086 19.1 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MoaC PF01967.21 KFY00564.1 - 2.1e-52 176.8 0.4 3.5e-52 176.1 0.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KFY00564.1 - 1.1e-35 122.4 0.0 3.8e-35 120.6 0.0 1.9 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFY00564.1 - 5.1e-27 95.3 0.0 1.2e-26 94.1 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFY00564.1 - 0.00072 19.8 0.1 0.0025 18.1 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Longin PF13774.6 KFY00564.1 - 0.16 12.1 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 Regulated-SNARE-like domain ANAPC4_WD40 PF12894.7 KFY00565.1 - 2.4e-08 34.2 0.0 0.26 11.6 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KFY00565.1 - 2.1e-06 26.1 0.0 3.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 IKI3 family WD40 PF00400.32 KFY00565.1 - 9.3e-05 23.1 4.8 3.3 8.7 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 KFY00565.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat EBP PF05241.12 KFY00566.1 - 2.7e-60 202.9 7.7 3.3e-60 202.6 7.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein Bac_surface_Ag PF01103.23 KFY00567.1 - 5e-47 161.0 0.8 6.3e-47 160.6 0.8 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 KFY00568.1 - 6.9e-20 71.1 0.1 9.6e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2 PF00096.26 KFY00570.1 - 0.0039 17.6 19.2 0.061 13.8 0.8 4.7 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-TRAF PF02176.18 KFY00570.1 - 0.053 14.2 0.7 0.18 12.5 0.7 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_4 PF13894.6 KFY00570.1 - 0.084 13.8 19.3 0.27 12.2 0.7 5.2 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KFY00570.1 - 0.095 12.6 2.9 0.21 11.5 2.9 1.5 1 0 0 1 1 1 0 Seven in absentia protein family zf-H2C2_2 PF13465.6 KFY00570.1 - 5.2 7.7 6.5 9 6.9 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain NmrA PF05368.13 KFY00571.1 - 1.1e-32 113.5 0.0 1.7e-32 112.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY00571.1 - 1.1e-07 32.0 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00571.1 - 0.0078 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFY00571.1 - 0.049 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_23 PF13489.6 KFY00572.1 - 4.1e-18 65.8 0.0 8.6e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00572.1 - 5.4e-08 33.4 0.0 1.4e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY00572.1 - 1.5e-05 24.8 0.0 0.0002 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY00572.1 - 0.0002 22.1 0.0 0.00071 20.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY00572.1 - 0.00034 21.2 0.0 0.00077 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFY00572.1 - 0.012 15.7 0.0 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFY00572.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KFY00572.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase HET PF06985.11 KFY00573.1 - 1.8e-35 122.5 0.8 4.9e-35 121.0 0.3 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KFY00573.1 - 0.03 13.5 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ketoacyl-synt PF00109.26 KFY00590.1 - 1.8e-80 270.2 0.0 4.3e-80 268.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFY00590.1 - 2.2e-36 124.5 0.0 5.7e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KFY00590.1 - 1.3e-32 113.6 2.0 1.9e-32 113.0 2.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KFY00590.1 - 4.9e-16 59.2 0.0 6.5e-15 55.6 0.0 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFY00590.1 - 3.4e-05 23.4 0.3 8e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 KFY00590.1 - 0.062 13.0 0.1 0.45 10.2 0.1 2.0 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Bunya_NS-S PF01104.17 KFY00590.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s DEAD PF00270.29 KFY00592.1 - 6.9e-48 162.7 0.0 1.3e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00592.1 - 3.7e-24 85.2 0.1 2.2e-23 82.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFY00592.1 - 2.3e-22 79.0 0.0 6e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFY00592.1 - 1e-06 28.9 0.0 2.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFY00593.1 - 4.6e-49 166.5 0.0 9.5e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00593.1 - 5.1e-24 84.8 0.0 2.2e-22 79.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFY00593.1 - 1.7e-22 79.4 3.6 5.4e-22 77.8 3.6 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KFY00593.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FAD_binding_4 PF01565.23 KFY00595.1 - 5.6e-20 71.5 0.9 1e-19 70.6 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY00595.1 - 2.9e-08 33.7 0.0 9e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like DUF3429 PF11911.8 KFY00641.1 - 9.9e-43 145.9 9.2 1.3e-42 145.5 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SET PF00856.28 KFY00656.1 - 0.035 14.5 0.0 0.08 13.3 0.0 1.7 1 0 0 1 1 1 0 SET domain SOG2 PF10428.9 KFY00657.1 - 0.5 9.5 7.7 0.57 9.3 7.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5427 PF10310.9 KFY00659.1 - 2.8e-148 494.8 0.0 3.4e-148 494.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KFY00659.1 - 0.008 16.4 0.3 0.032 14.4 0.2 2.0 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain Pkinase PF00069.25 KFY00660.1 - 2.5e-69 233.6 0.0 4.6e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00660.1 - 1.9e-31 109.3 0.0 2.9e-30 105.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFY00660.1 - 0.0062 16.5 0.1 0.12 12.3 0.0 2.7 1 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFY00660.1 - 0.0071 15.7 0.1 3.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KFY00660.1 - 0.046 13.3 0.2 0.11 12.0 0.2 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFY00660.1 - 0.065 12.0 2.4 0.28 9.9 2.4 1.9 1 1 0 1 1 1 0 Fungal protein kinase MFS_1 PF07690.16 KFY00662.1 - 1.1e-19 70.6 23.5 4.4e-13 48.9 0.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SYF2 PF08231.12 KFY00663.1 - 7.4e-55 185.7 14.5 7.4e-55 185.7 14.5 2.1 2 1 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 KFY00663.1 - 0.015 15.5 1.1 0.015 15.5 1.1 3.0 2 1 0 3 3 3 0 ARD/ARD' family POT1PC PF16686.5 KFY00663.1 - 0.17 11.8 2.3 1.4 8.8 0.4 2.4 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein Epimerase PF01370.21 KFY00664.1 - 4.9e-06 26.2 0.0 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY00664.1 - 1e-05 25.5 0.0 4.5e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFY00664.1 - 0.00039 19.5 0.0 0.00079 18.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFY00664.1 - 0.0069 15.6 0.0 0.051 12.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KFY00664.1 - 0.029 13.5 0.0 0.23 10.5 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFY00664.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFY00664.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF3667 PF12412.8 KFY00664.1 - 0.15 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) YEATS PF03366.16 KFY00665.1 - 4.8e-29 100.1 0.1 8.3e-29 99.4 0.1 1.4 1 0 0 1 1 1 1 YEATS family Med30 PF11315.8 KFY00665.1 - 0.05 13.8 0.1 0.081 13.1 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 TruB_C PF09142.11 KFY00665.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal DEAD PF00270.29 KFY00667.1 - 1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00667.1 - 1.2e-18 67.5 0.0 6.7e-17 61.8 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY00667.1 - 2.9e-05 24.2 0.0 7.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.6 KFY00668.1 - 4e-30 104.6 0.0 5.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00668.1 - 5.9e-25 87.8 0.2 1.6e-24 86.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY00668.1 - 1e-24 87.0 0.0 1.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY00668.1 - 2.4e-19 69.8 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY00668.1 - 4.5e-18 65.4 0.0 9.4e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY00668.1 - 6e-18 65.4 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFY00668.1 - 1.4e-08 34.5 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KFY00668.1 - 4.2e-07 29.7 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFY00668.1 - 1e-05 25.4 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KFY00668.1 - 5.8e-05 22.5 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KFY00668.1 - 0.00026 20.5 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KFY00668.1 - 0.00066 19.2 0.0 0.00091 18.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KFY00668.1 - 0.0017 17.0 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 KFY00668.1 - 0.0022 18.1 0.2 0.0037 17.4 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KFY00668.1 - 0.0035 16.3 0.0 0.0055 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 KFY00668.1 - 0.0063 16.2 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KFY00668.1 - 0.0074 15.6 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 KFY00668.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 KFY00668.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KFY00668.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 KFY00668.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit p450 PF00067.22 KFY00669.1 - 4e-58 197.3 0.0 4.9e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3851 PF12962.7 KFY00669.1 - 0.03 14.6 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Cpta_toxin PF07254.12 KFY00669.1 - 0.19 11.7 0.8 0.34 10.9 0.3 1.7 1 1 1 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system CBFD_NFYB_HMF PF00808.23 KFY00670.1 - 3.6e-13 49.6 1.4 6e-13 48.9 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFY00670.1 - 6.6e-05 23.3 0.5 6.6e-05 23.3 0.5 2.8 3 1 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 KFY00670.1 - 0.12 12.4 19.2 0.16 11.9 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF892 PF05974.12 KFY00672.1 - 0.0013 18.8 0.5 0.0013 18.8 0.5 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF892) WXG100 PF06013.12 KFY00672.1 - 0.004 17.4 0.7 1.5 9.1 0.0 3.4 2 1 0 2 2 2 1 Proteins of 100 residues with WXG TolA_bind_tri PF16331.5 KFY00672.1 - 0.0049 16.9 2.3 0.22 11.7 1.6 2.5 2 0 0 2 2 2 1 TolA binding protein trimerisation HALZ PF02183.18 KFY00672.1 - 0.011 16.0 0.8 0.03 14.6 0.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF948 PF06103.11 KFY00672.1 - 0.011 16.0 0.4 0.61 10.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 KFY00672.1 - 0.035 14.0 1.8 8.8 6.2 0.1 3.0 1 1 0 2 2 2 0 Sec34-like family EMP24_GP25L PF01105.24 KFY00672.1 - 0.05 13.5 0.5 0.05 13.5 0.5 2.2 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3450 PF11932.8 KFY00672.1 - 0.053 12.8 8.4 0.38 10.0 0.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 KFY00672.1 - 0.087 13.1 1.8 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KFY00672.1 - 0.089 12.9 9.8 0.46 10.6 1.7 2.7 2 1 0 2 2 2 0 bZIP transcription factor CK2S PF15011.6 KFY00672.1 - 0.093 12.6 4.9 3.9 7.3 0.2 2.7 2 1 0 2 2 2 0 Casein Kinase 2 substrate ANAPC4 PF12896.7 KFY00672.1 - 0.12 11.8 2.8 0.42 10.1 0.1 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 APG17 PF04108.12 KFY00672.1 - 0.15 11.1 10.2 0.85 8.7 7.6 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 Prominin PF05478.11 KFY00672.1 - 0.23 9.4 2.3 0.32 8.9 2.3 1.3 1 0 0 1 1 1 0 Prominin MscS_porin PF12795.7 KFY00672.1 - 0.23 11.0 3.7 4.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 KFY00672.1 - 0.23 11.5 5.8 6.2 6.9 0.2 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metal_resist PF13801.6 KFY00672.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.6 2 1 1 3 3 3 0 Heavy-metal resistance Fib_alpha PF08702.10 KFY00672.1 - 0.6 10.3 5.2 4.7 7.4 0.1 2.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KFY00672.1 - 0.7 10.0 11.2 2.7 8.1 0.2 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BCDHK_Adom3 PF10436.9 KFY00672.1 - 0.96 9.3 3.3 0.68 9.8 0.5 2.1 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CASP_C PF08172.12 KFY00672.1 - 0.97 8.7 7.5 0.51 9.6 5.7 1.4 2 0 0 2 2 2 0 CASP C terminal SpoVR PF04293.13 KFY00672.1 - 1.1 7.8 7.0 0.29 9.8 1.8 2.0 1 1 2 3 3 3 0 SpoVR like protein DUF4618 PF15397.6 KFY00672.1 - 1.2 8.5 10.7 1.2 8.5 2.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TACC_C PF05010.14 KFY00672.1 - 1.6 8.5 13.9 2.9 7.6 1.0 2.4 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Med9 PF07544.13 KFY00672.1 - 1.8 8.7 5.2 13 5.9 0.8 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 YabA PF06156.13 KFY00672.1 - 2 9.1 6.7 6.2 7.5 0.5 2.7 1 1 1 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 KFY00672.1 - 2.5 8.6 8.4 23 5.5 0.2 2.5 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Prefoldin PF02996.17 KFY00672.1 - 2.8 7.9 12.1 0.89 9.5 0.8 3.2 3 1 1 4 4 3 0 Prefoldin subunit FlaC_arch PF05377.11 KFY00672.1 - 7.4 7.0 7.8 11 6.5 0.2 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GrpE PF01025.19 KFY00672.1 - 9.9 5.8 16.6 30 4.2 1.2 4.2 2 1 3 5 5 5 0 GrpE CTP_synth_N PF06418.14 KFY00673.1 - 7.9e-125 415.5 0.2 1e-124 415.1 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFY00673.1 - 1.9e-55 187.6 0.0 3.6e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFY00673.1 - 1.1e-06 28.6 0.1 6.2e-06 26.1 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 Lyase_1 PF00206.20 KFY00674.1 - 1.2e-20 74.1 0.1 2.3e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFY00674.1 - 4.8e-14 52.7 0.0 1.9e-13 50.7 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF3328 PF11807.8 KFY00675.1 - 2e-26 93.2 0.5 2.6e-26 92.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TauD PF02668.16 KFY00691.1 - 1.9e-08 34.4 0.0 2.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_17 PF13207.6 KFY00692.1 - 0.0022 18.4 0.1 0.013 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFY00692.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KFY00692.1 - 0.028 13.7 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFY00692.1 - 0.029 14.9 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY00692.1 - 0.036 14.2 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFY00692.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFY00692.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 KFY00692.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aminotran_1_2 PF00155.21 KFY00693.1 - 1.7e-12 47.2 0.0 1.9e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CoA_transf_3 PF02515.17 KFY00693.1 - 0.034 13.3 0.0 0.037 13.2 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III Tmemb_170 PF10190.9 KFY00695.1 - 7.9e-21 74.4 11.8 9.2e-21 74.2 11.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep_2 PF14602.6 KFY00696.1 - 3.1e-12 46.0 9.0 8.7e-10 38.2 1.5 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KFY00696.1 - 6e-12 44.8 8.2 5.4e-09 35.4 2.4 3.4 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KFY00696.1 - 2.6e-11 43.6 0.0 4.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase SET PF00856.28 KFY00709.1 - 0.11 12.9 2.3 0.14 12.5 2.3 1.3 1 0 0 1 1 1 0 SET domain Mitofilin PF09731.9 KFY00709.1 - 0.13 11.1 16.9 0.15 10.9 16.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DDHD PF02862.17 KFY00709.1 - 0.23 11.6 1.8 0.29 11.3 1.8 1.3 1 0 0 1 1 1 0 DDHD domain AIF-MLS PF14962.6 KFY00709.1 - 0.28 11.1 16.3 0.42 10.6 16.3 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence SAGA-Tad1 PF12767.7 KFY00709.1 - 0.71 9.6 7.4 0.81 9.4 7.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DAG_kinase_N PF14513.6 KFY00709.1 - 1.2 9.3 5.3 1.9 8.7 5.3 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CDC45 PF02724.14 KFY00709.1 - 1.4 7.1 9.5 1.4 7.1 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 KFY00709.1 - 1.6 6.7 7.0 1.9 6.6 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMC3_TMCO1 PF01956.16 KFY00709.1 - 2 8.1 4.9 2.9 7.6 4.9 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Asp-B-Hydro_N PF05279.11 KFY00709.1 - 2.7 8.0 14.1 3.5 7.6 14.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 KFY00709.1 - 3.9 5.3 4.8 4.3 5.1 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 KFY00709.1 - 4.6 7.0 16.1 6.8 6.4 16.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3292 PF11696.8 KFY00709.1 - 5 5.4 11.1 7 4.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Presenilin PF01080.17 KFY00709.1 - 5.4 5.7 12.5 6 5.5 12.5 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 KFY00709.1 - 5.6 7.3 16.4 8.1 6.7 16.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.11 KFY00709.1 - 6.1 5.2 22.1 7.7 4.9 22.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 KFY00709.1 - 8.2 5.1 11.0 9.5 4.9 11.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDRGK PF09756.9 KFY00709.1 - 9.8 5.7 24.3 13 5.3 24.3 1.1 1 0 0 1 1 1 0 DDRGK domain Tyrosinase PF00264.20 KFY00717.1 - 7.3e-54 183.4 0.1 1e-53 182.9 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase XFP_N PF09364.10 KFY00718.1 - 3.3e-171 569.0 0.0 4.5e-171 568.6 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KFY00718.1 - 2.6e-84 281.7 0.0 3.7e-84 281.2 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KFY00718.1 - 1.1e-78 263.0 0.0 1.8e-78 262.3 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Fructosamin_kin PF03881.14 KFY00719.1 - 2.5e-28 99.1 0.0 3.1e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Sugar_tr PF00083.24 KFY00720.1 - 2.1e-114 382.9 25.2 2.9e-114 382.4 25.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00720.1 - 5.5e-15 55.2 38.1 1.1e-10 41.0 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PGAP1 PF07819.13 KFY00720.1 - 1.9e-05 24.5 2.1 9.5e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 PGAP1-like protein NACHT PF05729.12 KFY00720.1 - 2e-05 24.6 0.0 5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KFY00720.1 - 7.7e-05 22.3 0.9 0.00071 19.1 0.3 2.7 2 1 0 2 2 2 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 KFY00720.1 - 0.00029 21.2 0.0 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KFY00720.1 - 0.0082 16.8 0.9 0.049 14.2 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family GFA PF04828.14 KFY00720.1 - 0.035 14.4 0.3 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Lipase_2 PF01674.18 KFY00720.1 - 0.051 13.1 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) ATPase PF06745.13 KFY00720.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC Glyco_hydro_92 PF07971.12 KFY00721.1 - 2e-142 475.4 0.1 2.5e-142 475.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFY00721.1 - 3e-69 233.5 2.3 3.4e-69 233.3 1.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain AA_permease_2 PF13520.6 KFY00722.1 - 1.5e-83 281.0 44.0 1.5e-83 281.0 44.0 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1453 PF07301.11 KFY00722.1 - 0.026 14.5 0.5 0.026 14.5 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) MFS_1 PF07690.16 KFY00723.1 - 5.7e-18 64.9 28.6 5.7e-18 64.9 28.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00723.1 - 1.2e-10 40.9 17.4 4e-10 39.1 17.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Cytochrom_B558a PF05038.13 KFY00732.1 - 0.019 14.6 0.1 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit COX4_pro_2 PF07835.12 KFY00732.1 - 3.7 7.7 6.9 0.81 9.8 0.4 2.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Rieske PF00355.26 KFY00739.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KFY00739.1 - 6.5e-07 29.2 0.0 9.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain UvdE PF03851.14 KFY00741.1 - 9.5e-109 362.9 0.0 1.2e-108 362.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE F-box-like PF12937.7 KFY00742.1 - 2.5e-05 24.1 0.2 6.3e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY00742.1 - 0.077 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 F-box domain Methyltransf_2 PF00891.18 KFY00764.1 - 3.5e-18 65.7 0.0 5.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KFY00764.1 - 7e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KFY00764.1 - 0.00078 19.4 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 KFY00765.1 - 6e-20 71.7 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00765.1 - 1.6e-10 41.5 0.0 4.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY00765.1 - 1.8e-07 31.7 0.0 3.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY00765.1 - 7e-06 25.9 0.0 6.2e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY00765.1 - 3.5e-05 24.5 0.0 0.00013 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFY00765.1 - 0.0016 18.6 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.13 KFY00765.1 - 0.031 13.7 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFY00765.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KFY00765.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KFY00765.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ank_2 PF12796.7 KFY00766.1 - 2.4e-63 210.7 6.9 6.9e-15 55.4 0.5 7.9 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY00766.1 - 3.9e-41 138.9 2.0 3.9e-06 27.3 0.0 9.8 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY00766.1 - 1.3e-39 129.6 1.9 0.052 14.1 0.0 13.2 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 KFY00766.1 - 9.6e-36 120.7 3.9 0.0046 17.3 0.0 12.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KFY00766.1 - 5.3e-30 103.1 4.3 0.003 17.8 0.0 11.3 7 3 4 11 11 11 7 Ankyrin repeats (many copies) CorA PF01544.18 KFY00766.1 - 7.5e-07 28.7 0.2 2.1e-06 27.3 0.2 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fasciclin PF02469.22 KFY00767.1 - 7.4e-39 132.9 0.0 1.4e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Pyridoxal_deC PF00282.19 KFY00768.1 - 2e-60 204.5 0.0 2.8e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFY00768.1 - 1.7e-05 24.0 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Rhv PF00073.20 KFY00769.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 picornavirus capsid protein DUF4293 PF14126.6 KFY00769.1 - 0.17 12.1 5.5 0.055 13.7 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Glyco_hydro_45 PF02015.16 KFY00770.1 - 1.1e-54 185.6 15.5 1.3e-54 185.3 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Flavoprotein PF02441.19 KFY00771.1 - 9.2e-44 149.0 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Zn_clus PF00172.18 KFY00772.1 - 1.9e-08 34.3 5.1 1.9e-08 34.3 5.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY00772.1 - 0.022 13.6 1.2 0.034 13.0 1.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.13 KFY00773.1 - 5.5e-39 133.9 9.4 9.5e-39 133.1 9.4 1.3 1 0 0 1 1 1 1 RTA1 like protein CBM_1 PF00734.18 KFY00774.1 - 1.8e-08 34.2 11.6 4.2e-08 33.0 11.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_11 PF03425.13 KFY00774.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) PBP_like_2 PF12849.7 KFY00775.1 - 1.5e-08 34.7 0.2 2e-08 34.3 0.2 1.1 1 0 0 1 1 1 1 PBP superfamily domain adh_short_C2 PF13561.6 KFY00776.1 - 3e-52 177.5 0.0 4.2e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY00776.1 - 7.8e-49 165.8 0.2 9.7e-49 165.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY00776.1 - 4.8e-10 39.6 0.0 6.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00776.1 - 0.0022 17.5 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFY00776.1 - 0.0023 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KFY00776.1 - 0.0057 16.1 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 KFY00776.1 - 0.041 13.2 0.2 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFY00776.1 - 0.043 13.1 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KFY00776.1 - 0.045 12.9 0.2 0.054 12.6 0.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 KFY00776.1 - 0.056 13.2 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 KFY00776.1 - 0.058 13.8 0.3 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 KFY00776.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HET PF06985.11 KFY00777.1 - 8.9e-11 42.3 0.0 1.2e-09 38.7 0.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.14 KFY00777.1 - 1.7e-09 37.8 0.1 4.8e-09 36.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_24 PF13578.6 KFY00778.1 - 3.4e-12 47.3 0.0 6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KFY00778.1 - 4.4e-07 29.3 0.1 1.8e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase WD40 PF00400.32 KFY00779.1 - 1.1e-06 29.2 15.8 0.0028 18.4 0.1 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KFY00779.1 - 0.00026 20.5 11.1 0.00056 19.5 11.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KFY00779.1 - 0.43 11.0 5.6 0.97 9.8 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain DUF1275 PF06912.11 KFY00785.1 - 1.4e-48 165.4 10.0 1.8e-48 165.1 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Bax1-I PF01027.20 KFY00785.1 - 1.2 8.9 10.1 0.94 9.3 5.1 2.2 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.6 KFY00785.1 - 5.5 6.6 7.4 0.61 9.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ABC_tran PF00005.27 KFY00786.1 - 1.1e-47 162.0 0.1 2.3e-25 89.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFY00786.1 - 4.3e-14 53.0 8.3 0.0028 17.5 0.0 4.6 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFY00786.1 - 3.5e-12 46.2 0.7 0.0035 16.8 0.1 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFY00786.1 - 1.3e-09 38.9 0.1 0.00052 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFY00786.1 - 8.8e-08 31.8 1.1 0.0052 16.5 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFY00786.1 - 8.4e-07 29.1 0.0 0.045 13.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY00786.1 - 1.7e-06 28.0 0.2 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Chromo PF00385.24 KFY00786.1 - 2.4e-06 27.4 0.2 4.7e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 KFY00786.1 - 1.9e-05 24.6 0.6 0.075 12.7 0.3 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KFY00786.1 - 0.00027 21.2 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFY00786.1 - 0.0013 19.3 0.0 3.2 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KFY00786.1 - 0.0015 18.8 0.4 2.3 8.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KFY00786.1 - 0.0029 17.8 0.7 0.45 10.6 0.2 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_13 PF13166.6 KFY00786.1 - 0.0037 16.0 0.0 0.73 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KFY00786.1 - 0.011 15.9 0.1 4.7 7.5 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 KFY00786.1 - 0.018 14.9 0.2 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 KFY00786.1 - 0.019 14.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFY00786.1 - 0.019 14.7 0.5 8.8 6.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KFY00786.1 - 0.021 14.6 0.1 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KFY00786.1 - 0.034 13.1 0.3 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KFY00786.1 - 0.046 13.9 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFY00786.1 - 0.046 14.1 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 RNA helicase DUF3584 PF12128.8 KFY00786.1 - 0.057 10.9 2.4 2.2 5.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Dynamin_N PF00350.23 KFY00786.1 - 0.057 13.5 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Dynamin family ALF PF03752.13 KFY00786.1 - 0.062 13.3 2.5 0.69 9.9 1.5 2.6 2 0 0 2 2 2 0 Short repeats of unknown function DUF815 PF05673.13 KFY00786.1 - 0.07 12.3 0.1 9.3 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 KFY00786.1 - 0.088 12.7 0.4 7.7 6.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KFY00786.1 - 0.16 11.2 0.7 8 5.7 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin SR-25 PF10500.9 KFY00786.1 - 0.22 11.1 2.9 0.41 10.2 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 KFY00786.1 - 0.31 11.4 2.0 85 3.8 0.3 4.3 4 0 0 4 4 4 0 HEAT repeat AAA_24 PF13479.6 KFY00786.1 - 0.46 10.2 2.0 7.3 6.3 0.4 2.4 2 0 0 2 2 2 0 AAA domain HET PF06985.11 KFY00787.1 - 4.2e-23 82.3 0.0 7.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 KFY00788.1 - 5.4e-62 209.4 0.1 6.5e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY00788.1 - 6.4e-42 143.2 0.0 7.9e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY00788.1 - 2.2e-09 37.5 0.8 3.3e-09 36.9 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFY00788.1 - 0.0002 21.3 0.1 0.00034 20.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 KFY00788.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00788.1 - 0.0014 19.3 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KFY00788.1 - 0.0029 16.8 0.1 0.0042 16.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 KFY00788.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KFY00788.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 KFY00788.1 - 0.078 12.8 0.0 0.55 10.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MoaC PF01967.21 KFY00788.1 - 0.083 13.0 0.4 1 9.4 0.1 2.2 1 1 2 3 3 3 0 MoaC family ChuX_HutX PF06228.13 KFY00788.1 - 0.092 12.5 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX TPMT PF05724.11 KFY00788.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KFY00788.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 KFY00789.1 - 1.1e-84 284.4 0.0 1.3e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SKG6 PF08693.10 KFY00791.1 - 3.3e-10 39.2 0.1 5.9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glyco_transf_92 PF01697.27 KFY00794.1 - 1.5e-10 41.2 0.1 7.3e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFY00794.1 - 3.1e-10 40.4 1.1 5.6e-10 39.6 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Citrate_synt PF00285.21 KFY00795.1 - 1.9e-97 326.6 0.0 2.3e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 KFY00796.1 - 2.7e-198 659.8 0.1 3.1e-198 659.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFY00796.1 - 4.4e-10 39.4 0.1 2.3e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 KFY00796.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Glyco_hydro_61 PF03443.14 KFY00797.1 - 4e-62 209.8 0.4 4.9e-62 209.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydrophobin PF01185.18 KFY00798.1 - 1.1e-05 26.0 11.9 1.1e-05 26.0 11.9 1.9 2 1 0 2 2 2 1 Fungal hydrophobin MF_alpha_N PF05436.11 KFY00798.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Pkinase PF00069.25 KFY00805.1 - 2.6e-34 118.8 0.0 5.6e-17 62.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00805.1 - 2.3e-11 43.5 0.0 0.00056 19.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase FTA2 PF13095.6 KFY00805.1 - 0.0038 16.9 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFY00805.1 - 0.0094 15.9 0.0 0.04 13.8 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFY00805.1 - 0.081 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFY00805.1 - 0.18 11.1 0.0 11 5.3 0.0 2.8 3 1 0 3 3 3 0 Kinase-like PhoLip_ATPase_C PF16212.5 KFY00806.1 - 7.1e-77 258.5 22.1 7.1e-77 258.5 22.1 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFY00806.1 - 4.8e-18 64.6 0.5 4.8e-18 64.6 0.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFY00806.1 - 1.9e-12 47.1 0.0 1.2e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFY00806.1 - 2.3e-10 41.1 0.2 2.8e-06 27.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFY00806.1 - 0.0095 15.5 0.0 0.0095 15.5 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFY00806.1 - 0.012 15.4 0.4 0.032 14.0 0.4 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PX PF00787.24 KFY00807.1 - 2.2e-21 75.9 0.7 3.9e-21 75.2 0.2 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFY00807.1 - 2.4e-09 37.1 8.7 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Occludin_ELL PF07303.13 KFY00807.1 - 0.037 14.7 0.3 2.8 8.7 0.0 3.3 2 1 1 3 3 3 0 Occludin homology domain Dynactin_p22 PF07426.11 KFY00807.1 - 0.066 13.1 0.1 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 FlaC_arch PF05377.11 KFY00807.1 - 1.5 9.3 3.6 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) hGDE_N PF14699.6 KFY00808.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme SKG6 PF08693.10 KFY00809.1 - 0.00039 19.8 0.9 0.00039 19.8 0.9 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2207 PF09972.9 KFY00809.1 - 0.015 14.1 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 KFY00809.1 - 0.032 13.6 0.3 0.051 13.0 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SOG2 PF10428.9 KFY00809.1 - 0.46 9.6 14.0 0.56 9.4 14.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KFY00809.1 - 0.92 9.4 8.4 1.1 9.1 8.4 1.2 1 0 0 1 1 1 0 SPX domain LETM1 PF07766.13 KFY00810.1 - 1.9e-103 345.5 0.2 1.9e-103 345.5 0.2 1.6 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KFY00810.1 - 0.00028 20.6 0.0 0.0036 17.0 0.0 2.7 3 0 0 3 3 3 1 SAP domain YchF-GTPase_C PF06071.13 KFY00812.1 - 5.4e-37 125.9 0.1 1.4e-36 124.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFY00812.1 - 1.4e-05 25.1 0.1 4.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MMR_HSR1 PF01926.23 KFY00813.1 - 3.4e-12 46.5 0.0 4.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY00813.1 - 7.1e-08 32.1 0.0 8.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KFY00813.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase OPT PF03169.15 KFY00814.1 - 3.2e-89 300.2 44.6 3.8e-89 300.0 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.24 KFY00815.1 - 2.6e-97 326.5 26.4 3.2e-97 326.3 26.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00815.1 - 2.3e-34 118.9 46.5 1.5e-30 106.3 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 KFY00815.1 - 2.7e-05 24.5 0.0 6.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFY00815.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFY00815.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OATP PF03137.20 KFY00815.1 - 0.0079 14.5 0.8 0.0079 14.5 0.8 2.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family GST_C_2 PF13410.6 KFY00815.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Gmad1 PF10647.9 KFY00815.1 - 0.084 12.6 1.5 1.6 8.4 0.1 2.6 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain GST_C PF00043.25 KFY00815.1 - 0.089 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2615 PF11027.8 KFY00815.1 - 0.67 10.1 5.2 1.5 9.0 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) CE2_N PF17996.1 KFY00816.1 - 1.9e-20 72.8 0.0 3.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 KFY00816.1 - 1e-14 55.4 2.3 1.6e-14 54.7 2.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 KFY00816.1 - 1.4e-13 50.5 7.5 3.3e-13 49.3 7.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KFY00816.1 - 2e-06 27.9 0.2 3.1e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PTR2 PF00854.21 KFY00818.1 - 4.4e-79 266.1 8.0 6.5e-79 265.6 8.0 1.2 1 0 0 1 1 1 1 POT family FAD_binding_4 PF01565.23 KFY00819.1 - 2.9e-21 75.7 0.3 7.1e-21 74.4 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY00819.1 - 0.032 14.3 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro2_C5 PF18565.1 KFY00820.1 - 3.2e-30 104.0 0.3 6.5e-30 103.0 0.3 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KFY00820.1 - 5.8e-27 94.6 0.0 1.3e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KFY00820.1 - 3.3e-22 78.2 0.1 7.6e-22 77.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2 PF00703.21 KFY00820.1 - 5.7e-17 62.4 0.3 1.2e-16 61.3 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFY00820.1 - 9.1e-16 58.2 0.0 1e-14 54.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KFY00820.1 - 6.6e-05 23.4 0.0 0.002 18.7 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KFY00820.1 - 0.064 13.6 8.9 0.2 12.0 2.8 2.9 2 0 0 2 2 2 0 Invasin, domain 3 adh_short PF00106.25 KFY00821.1 - 2.4e-36 125.1 0.0 4.3e-36 124.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00821.1 - 7.9e-28 97.6 0.0 9.7e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KFY00821.1 - 0.00053 19.9 0.1 0.00082 19.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KFY00821.1 - 0.0042 17.0 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFY00821.1 - 0.099 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KFY00821.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFY00821.1 - 0.17 11.9 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DSBA PF01323.20 KFY00822.1 - 2.5e-16 60.0 0.0 2.9e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Lactococcin PF04369.13 KFY00822.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family NAD_binding_8 PF13450.6 KFY00825.1 - 3.3e-14 52.9 0.0 8.9e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY00825.1 - 5.2e-05 23.0 0.0 0.0019 17.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFY00825.1 - 0.0002 21.4 0.1 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KFY00825.1 - 0.00026 20.4 0.0 0.00067 19.0 0.0 1.7 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY00825.1 - 0.00026 20.3 0.0 0.0034 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY00825.1 - 0.0058 15.7 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KFY00825.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 KFY00825.1 - 0.043 12.5 0.1 0.34 9.6 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein K_oxygenase PF13434.6 KFY00825.1 - 0.047 12.8 0.9 0.4 9.8 0.1 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Spo0A_C PF08769.11 KFY00825.1 - 0.091 12.9 0.1 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Pyr_redox PF00070.27 KFY00825.1 - 0.15 12.6 0.3 1 9.9 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 KFY00826.1 - 5.8e-24 85.7 0.9 1.3e-23 84.5 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFY00826.1 - 8.7e-15 54.9 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 KFY00827.1 - 6.2e-79 266.0 22.2 7.6e-79 265.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00827.1 - 6.7e-31 107.5 38.9 1.3e-24 86.8 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5542 PF17696.1 KFY00827.1 - 0.096 12.8 1.7 0.19 11.9 1.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF5607 PF18355.1 KFY00834.1 - 0.18 12.3 4.2 0.97 9.9 4.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5607) PNP_UDP_1 PF01048.20 KFY00835.1 - 0.0013 18.1 0.0 0.017 14.4 0.0 2.3 2 1 0 2 2 2 1 Phosphorylase superfamily zf-RING_UBOX PF13445.6 KFY00836.1 - 1.3e-06 28.3 5.0 3.1e-06 27.1 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH PF00642.24 KFY00836.1 - 1.5e-06 27.9 2.3 1.5e-06 27.9 2.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KFY00836.1 - 3e-06 27.0 4.7 6.6e-06 25.9 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY00836.1 - 5.3e-06 26.2 6.3 1.3e-05 25.0 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY00836.1 - 1.1e-05 25.2 6.5 2.3e-05 24.2 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY00836.1 - 1.8e-05 24.6 7.3 3.9e-05 23.5 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 KFY00836.1 - 0.0002 21.4 3.3 0.00028 20.9 2.3 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 CorA PF01544.18 KFY00836.1 - 0.00032 20.1 4.1 0.00032 20.1 4.1 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein zf_CCCH_4 PF18345.1 KFY00836.1 - 0.00044 20.2 5.8 0.00044 20.2 5.8 1.9 2 0 0 2 2 2 1 Zinc finger domain zf-RING_2 PF13639.6 KFY00836.1 - 0.00058 20.1 5.8 0.0016 18.7 5.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KFY00836.1 - 0.0013 18.5 2.6 0.0013 18.5 2.6 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 KFY00836.1 - 0.013 15.7 6.5 0.031 14.5 6.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFY00836.1 - 0.014 15.2 5.8 0.031 14.1 5.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 E3_UbLigase_R4 PF13764.6 KFY00836.1 - 0.13 10.4 0.2 0.2 9.7 0.2 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 zf-CCCH_2 PF14608.6 KFY00836.1 - 1.4 9.5 5.5 0.93 10.1 3.2 2.0 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-PARP PF00645.18 KFY00851.1 - 5.4e-20 72.0 0.1 5.4e-20 72.0 0.1 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Amidase PF01425.21 KFY00852.1 - 5e-75 253.2 0.1 7.8e-73 246.0 0.1 2.1 1 1 0 1 1 1 1 Amidase HypD PF01924.16 KFY00873.1 - 0.00067 18.8 2.3 1.2 8.2 0.1 3.5 3 2 1 4 4 4 2 Hydrogenase formation hypA family zf-ZPR1 PF03367.13 KFY00873.1 - 0.002 18.0 4.7 10 5.9 0.1 4.7 1 1 4 5 5 5 3 ZPR1 zinc-finger domain YadA_stalk PF05662.14 KFY00873.1 - 0.063 13.6 11.6 21 5.6 0.4 5.1 4 0 0 4 4 4 0 Coiled stalk of trimeric autotransporter adhesin Plasmid_stab_B PF10784.9 KFY00873.1 - 7.2 6.5 12.5 29 4.6 0.1 4.5 4 0 0 4 4 4 0 Plasmid stability protein MAPEG PF01124.18 KFY00883.1 - 2e-22 79.5 1.4 2.3e-22 79.3 1.4 1.1 1 0 0 1 1 1 1 MAPEG family DUF2428 PF10350.9 KFY00884.1 - 2.4e-57 194.3 0.2 8.4e-57 192.5 0.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KFY00884.1 - 0.017 15.3 0.5 12 6.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat TEX15 PF15326.6 KFY00884.1 - 0.032 13.9 1.9 0.05 13.3 0.6 1.8 2 0 0 2 2 2 0 Testis expressed sequence 15 MOR2-PAG1_C PF14225.6 KFY00884.1 - 0.048 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Cell morphogenesis C-terminal NEMP PF10225.9 KFY00884.1 - 0.078 12.6 0.1 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 NEMP family MMS22L_C PF14911.6 KFY00884.1 - 0.13 11.4 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Tim17 PF02466.19 KFY00885.1 - 1.4e-25 89.8 3.6 2.1e-25 89.3 3.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.29 KFY00886.1 - 3.1e-68 230.0 0.0 5.9e-68 229.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFY00886.1 - 7.8e-10 38.8 0.0 0.0016 18.1 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFY00886.1 - 5.7e-08 33.3 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Zn_ribbon_SprT PF17283.2 KFY00886.1 - 5.1 7.1 4.6 1.2 9.0 0.7 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DDOST_48kD PF03345.14 KFY00903.1 - 4.8e-161 536.2 0.0 5.5e-161 536.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SRR1 PF07985.12 KFY00905.1 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 KFY00905.1 - 0.034 14.3 1.4 0.059 13.5 1.4 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain adh_short PF00106.25 KFY00906.1 - 5.1e-40 137.0 0.3 7.7e-40 136.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00906.1 - 6.1e-28 98.0 1.0 8.4e-28 97.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFY00906.1 - 1.6e-05 24.9 0.2 3.3e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KFY00906.1 - 0.0087 16.0 0.7 0.021 14.8 0.6 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Exo_endo_phos PF03372.23 KFY00907.1 - 0.0018 17.8 0.0 0.0074 15.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DHHC PF01529.20 KFY00912.1 - 1.2e-31 109.6 2.9 1.2e-31 109.6 2.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase YwiC PF14256.6 KFY00912.1 - 0.42 10.9 5.0 1.7 9.0 1.0 2.2 2 0 0 2 2 2 0 YwiC-like protein Jacalin PF01419.17 KFY00913.1 - 0.019 14.9 0.1 0.055 13.4 0.1 1.9 1 1 0 1 1 1 0 Jacalin-like lectin domain Acetyltransf_1 PF00583.25 KFY00914.1 - 1.2e-11 44.8 0.0 8e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY00914.1 - 2.1e-09 37.4 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY00914.1 - 5.1e-09 36.4 0.1 1.7e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY00914.1 - 0.00052 20.1 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFY00914.1 - 0.0063 16.6 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DHquinase_I PF01487.15 KFY00915.1 - 1.7e-23 84.1 0.0 2.7e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFY00915.1 - 8.7e-18 64.9 0.0 1.6e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 KFY00915.1 - 3.5e-13 49.6 0.1 7e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFY00915.1 - 1.8e-09 37.2 0.2 4.2e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFY00915.1 - 8.1e-08 32.4 0.2 2.3e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 KFY00916.1 - 6.6e-20 71.2 0.2 1.3e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00916.1 - 3.7e-08 33.3 11.4 6.3e-08 32.6 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFY00925.1 - 2.3e-121 405.8 22.6 2.6e-121 405.6 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00925.1 - 5.8e-20 71.5 29.1 5.8e-20 71.5 29.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Tropomyosin PF00261.20 KFY00926.1 - 0.00058 19.3 1.8 0.001 18.5 1.8 1.3 1 0 0 1 1 1 1 Tropomyosin DHR10 PF18595.1 KFY00926.1 - 0.025 14.6 2.7 0.025 14.6 2.7 1.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 KFY00926.1 - 0.03 14.8 0.4 5.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 KFY00926.1 - 0.19 12.4 7.4 2.6 8.7 0.3 3.0 2 1 1 3 3 3 0 SlyX Nse4_C PF08743.10 KFY00932.1 - 9.9e-35 118.7 0.0 1.5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Nse4 C-terminal DNApol_Exo PF18136.1 KFY00938.1 - 1.1e-104 349.5 0.0 1.9e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFY00938.1 - 5.6e-59 200.1 0.0 1e-58 199.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Ribosomal_L16 PF00252.18 KFY00939.1 - 3.4e-39 133.9 0.7 4.4e-39 133.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C3HC4_3 PF13920.6 KFY00940.1 - 2e-11 43.5 5.2 3.1e-11 43.0 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFY00940.1 - 9.9e-09 34.9 6.6 1.7e-08 34.2 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFY00940.1 - 1.5e-08 34.3 6.5 2.4e-08 33.7 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY00940.1 - 6.4e-08 32.3 8.6 1e-07 31.6 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFY00940.1 - 3.8e-07 30.3 7.5 5.9e-07 29.7 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFY00940.1 - 4.5e-07 29.7 7.3 7.3e-07 29.1 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFY00940.1 - 4.5e-05 23.4 2.6 4.5e-05 23.4 2.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFY00940.1 - 0.00072 19.3 4.4 0.0014 18.4 4.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFY00940.1 - 0.00093 19.4 4.8 0.0018 18.5 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFY00940.1 - 0.0026 17.8 3.1 0.0043 17.1 3.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFY00940.1 - 0.0049 16.7 1.6 0.0083 16.0 1.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFY00940.1 - 0.0098 16.0 6.4 0.02 15.1 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFY00940.1 - 0.06 13.3 0.2 0.085 12.8 0.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RR_TM4-6 PF06459.12 KFY00940.1 - 0.099 12.4 1.8 0.15 11.8 1.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0052 PF01933.18 KFY00941.1 - 3.7e-59 200.4 0.0 4.4e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.27 KFY00942.1 - 3.5e-54 184.3 0.0 1.2e-53 182.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KFY00942.1 - 1.5e-39 135.5 2.7 9.2e-39 133.0 0.3 3.3 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KFY00942.1 - 2.1e-11 43.4 0.2 2.2e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 FATC domain Nup192 PF11894.8 KFY00943.1 - 0 1383.0 12.6 0 1382.8 12.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 FANCI_S4 PF14678.6 KFY00943.1 - 0.078 12.1 0.1 0.19 10.8 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 4 Cullin PF00888.22 KFY00944.1 - 5.9e-168 560.3 5.5 7.4e-168 560.0 5.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFY00944.1 - 6.6e-25 86.9 0.6 2.4e-24 85.1 0.6 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Glyco_hydro_28 PF00295.17 KFY00945.1 - 2.7e-94 315.9 19.5 3.7e-94 315.4 19.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Catalase PF00199.19 KFY00946.1 - 2.7e-171 569.9 0.3 3.4e-171 569.6 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFY00946.1 - 5.1e-17 61.8 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KFY00946.1 - 3.7e-13 49.4 0.6 7.8e-13 48.3 0.6 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KFY00946.1 - 9e-13 48.4 0.1 1.6e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family LUC7 PF03194.15 KFY00947.1 - 2.7e-69 233.6 0.1 2.7e-69 233.6 0.1 2.3 2 0 0 2 2 2 1 LUC7 N_terminus HEPN_Apea PF18739.1 KFY00947.1 - 4.1 7.9 6.8 0.3 11.5 0.4 2.3 3 0 0 3 3 3 0 Apea-like HEPN Gpi16 PF04113.14 KFY00948.1 - 3.2e-240 798.4 0.0 4e-240 798.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DJ-1_PfpI PF01965.24 KFY00949.1 - 8.3e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFY00949.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Birna_VP5 PF03042.14 KFY00950.1 - 0.0045 17.0 1.2 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Birnavirus VP5 protein zf-HC5HC2H_2 PF13832.6 KFY00965.1 - 5.9e-32 110.1 8.3 5.9e-32 110.1 8.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KFY00965.1 - 5.9e-28 98.2 0.0 4.9e-27 95.3 0.0 2.6 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KFY00965.1 - 8.1e-26 90.1 17.0 1.3e-25 89.4 8.4 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KFY00965.1 - 1.1e-14 53.7 1.9 3.1e-14 52.2 1.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KFY00965.1 - 8.3e-09 35.2 24.6 1.2e-08 34.7 9.5 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KFY00965.1 - 0.016 14.8 1.6 0.016 14.8 1.6 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF3221 PF11518.8 KFY00965.1 - 0.035 14.5 0.4 0.093 13.1 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) PUFD PF16553.5 KFY00965.1 - 0.67 10.1 1.9 0.69 10.1 0.1 1.9 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain EMC1_C PF07774.13 KFY00972.1 - 2.5e-26 92.7 0.0 6.4e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KFY00972.1 - 1.4e-24 87.0 12.6 1.5e-20 73.8 9.7 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 KFY00972.1 - 0.00091 19.6 2.3 0.063 13.8 0.1 3.5 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.21 KFY00972.1 - 0.0019 18.0 8.2 0.88 9.6 0.0 5.1 5 0 0 5 5 5 2 PQQ enzyme repeat CNH PF00780.22 KFY00973.1 - 4e-71 239.9 0.0 5.7e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KFY00973.1 - 9.1e-28 97.7 0.6 1.8e-27 96.7 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KFY00973.1 - 3.8e-13 49.7 0.1 2.5e-12 47.1 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFY00973.1 - 0.00019 21.9 0.0 0.0023 18.4 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFY00973.1 - 0.0028 17.5 0.3 0.68 9.7 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_16 PF17838.1 KFY00973.1 - 0.021 14.7 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 PH domain CBFD_NFYB_HMF PF00808.23 KFY00988.1 - 5.3e-10 39.4 0.0 9.6e-10 38.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFY00988.1 - 4.6e-07 30.3 0.0 6.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFY00988.1 - 1.1e-05 25.5 0.0 1.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAFII28 PF04719.14 KFY00988.1 - 0.0079 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Bromo_TP PF07524.13 KFY00988.1 - 0.0098 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PPE PF00823.19 KFY00988.1 - 0.014 15.5 0.2 0.019 15.1 0.2 1.2 1 0 0 1 1 1 0 PPE family BBS2_N PF14781.6 KFY00988.1 - 0.11 12.5 0.1 0.45 10.4 0.0 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal SLD3 PF08639.10 KFY00989.1 - 1.8e-139 466.0 12.0 1.8e-139 466.0 12.0 2.0 2 1 0 2 2 2 1 DNA replication regulator SLD3 zf-H2C2_2 PF13465.6 KFY00992.1 - 1.7e-12 47.1 9.4 2.6e-07 30.7 0.4 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFY00992.1 - 3.4e-12 46.1 12.8 3.6e-06 27.1 2.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY00992.1 - 1.9e-08 34.4 11.3 0.0004 21.0 1.5 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFY00992.1 - 4.7e-08 32.8 6.5 0.00032 20.6 0.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFY00992.1 - 1.3e-06 28.5 2.0 0.088 13.1 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY00992.1 - 3.6e-05 24.0 1.7 0.013 15.8 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFY00992.1 - 0.048 14.0 2.6 0.087 13.1 1.9 1.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFY00992.1 - 0.57 10.0 8.3 0.41 10.4 0.7 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type LIM PF00412.22 KFY00992.1 - 5.7 7.2 8.2 18 5.7 0.1 3.1 2 1 1 3 3 3 0 LIM domain C5HCH PF17982.1 KFY00992.1 - 7 6.9 7.0 33 4.7 1.4 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain DNA_pol_E_B PF04042.16 KFY01008.1 - 1.3e-48 165.2 0.0 1.8e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3915 PF13054.6 KFY01009.1 - 0.67 9.9 5.4 2.6 8.1 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PRELI PF04707.14 KFY01010.1 - 3.6e-24 85.4 0.0 2.5e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.25 KFY01011.1 - 2.4e-18 66.5 0.0 6.3e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) UPF0515 PF15135.6 KFY01015.1 - 0.036 13.4 0.1 0.045 13.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 LytB_WW PF18342.1 KFY01016.1 - 0.0035 17.4 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 Endo-beta-N-acetylglucosaminidase LytB WW domain MRP-L20 PF12824.7 KFY01018.1 - 3.9e-58 196.2 3.0 4.4e-58 196.1 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Tyr_Deacylase PF02580.16 KFY01019.1 - 7.8e-51 172.4 0.2 8.8e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Aminotran_4 PF01063.19 KFY01020.1 - 8.1e-26 91.2 0.0 1.9e-24 86.8 0.0 2.1 1 1 0 1 1 1 1 Amino-transferase class IV CRM1_repeat_2 PF18784.1 KFY01020.1 - 0.035 13.7 0.2 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 HSP70 PF00012.20 KFY01039.1 - 1.8e-257 855.4 5.0 2.1e-257 855.2 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFY01039.1 - 5.7e-17 61.5 0.0 9.5e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFY01039.1 - 0.002 17.9 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFY01039.1 - 0.024 15.1 3.1 10 6.6 0.2 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 KFY01039.1 - 0.03 13.6 0.1 0.07 12.4 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KFY01039.1 - 0.044 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein E1-E2_ATPase PF00122.20 KFY01040.1 - 1.1e-36 126.1 0.4 1.1e-36 126.1 0.4 2.2 2 0 0 2 2 2 1 E1-E2 ATPase PP2C PF00481.21 KFY01040.1 - 1.2e-31 110.3 0.0 1.6e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Cation_ATPase_C PF00689.21 KFY01040.1 - 6.2e-29 101.0 6.1 6.2e-29 101.0 6.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFY01040.1 - 3.3e-20 73.3 0.2 5.4e-15 56.3 0.0 3.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY01040.1 - 1.5e-13 50.6 0.0 3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFY01040.1 - 3e-10 39.6 0.0 6.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFY01040.1 - 0.0011 18.8 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 KFY01040.1 - 0.003 17.4 0.0 0.003 17.4 0.0 3.5 3 0 0 3 3 3 1 Predicted membrane protein (DUF2157) DUF2231 PF09990.9 KFY01040.1 - 0.1 13.1 0.5 0.37 11.2 0.5 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF3844 PF12955.7 KFY01057.1 - 5.3e-33 113.3 2.3 5.3e-33 113.3 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) GNAT_acetyltr_2 PF13718.6 KFY01058.1 - 4.8e-96 320.6 0.0 9.7e-96 319.6 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFY01058.1 - 1.2e-89 300.1 0.0 2e-89 299.3 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFY01058.1 - 1.1e-64 217.5 0.0 4e-64 215.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFY01058.1 - 1.9e-34 117.5 0.0 4.7e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KFY01058.1 - 0.00028 20.7 0.1 0.027 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFY01058.1 - 0.00077 19.8 0.0 0.042 14.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 KFY01058.1 - 0.11 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_transf_90 PF05686.12 KFY01059.1 - 0.072 12.0 0.2 9.3 5.0 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 90 Tmpp129 PF10272.9 KFY01059.1 - 0.18 11.0 1.4 0.22 10.8 0.2 1.6 2 0 0 2 2 2 0 Putative transmembrane protein precursor Lipase_3 PF01764.25 KFY01060.1 - 1.6e-31 109.1 0.0 2.3e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFY01060.1 - 0.013 16.1 0.1 0.017 15.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01060.1 - 0.043 13.1 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFY01060.1 - 0.087 12.9 0.8 0.14 12.3 0.8 1.2 1 0 0 1 1 1 0 Thioesterase domain NmrA PF05368.13 KFY01061.1 - 8.5e-13 48.4 0.0 8.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KFY01061.1 - 0.00075 19.4 0.0 0.0036 17.2 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding Cellulase PF00150.18 KFY01062.1 - 2.6e-49 168.2 0.0 3.3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rib PF08428.10 KFY01062.1 - 0.033 14.2 0.1 0.97 9.5 0.1 2.8 3 0 0 3 3 3 0 Rib/alpha-like repeat XLF PF09302.11 KFY01063.1 - 2.3e-46 158.2 0.1 2.3e-46 158.2 0.1 2.4 3 0 0 3 3 3 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component SPESP1 PF15754.5 KFY01063.1 - 1.6 7.9 10.5 3.8 6.6 10.5 1.6 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF3807 PF12720.7 KFY01064.1 - 2.6e-36 125.6 6.0 3.7e-36 125.1 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Forkhead PF00250.18 KFY01065.1 - 1.2e-17 63.9 0.0 2.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 KFY01066.1 - 2.1e-66 223.4 8.9 3.6e-66 222.7 8.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KFY01066.1 - 5.5e-58 194.3 6.1 9.2e-58 193.6 6.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KFY01066.1 - 0.017 15.5 0.0 0.068 13.5 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) TPR_20 PF14561.6 KFY01066.1 - 0.024 15.0 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat YolD PF08863.10 KFY01066.1 - 0.071 13.2 1.2 0.55 10.3 0.1 2.4 2 0 0 2 2 2 0 YolD-like protein DUF1087 PF06465.13 KFY01066.1 - 0.2 11.7 2.6 0.47 10.5 0.5 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Mucin-like PF16058.5 KFY01066.1 - 0.3 11.2 5.9 0.11 12.6 1.2 2.1 2 0 0 2 2 2 0 Mucin-like Atg14 PF10186.9 KFY01067.1 - 1.7e-12 47.1 14.4 2.8e-11 43.1 9.6 2.9 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFY01067.1 - 4.2e-09 35.8 3.1 0.0033 16.4 0.8 3.7 3 1 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KFY01067.1 - 0.00023 21.2 0.0 0.00073 19.5 0.0 1.8 1 1 1 2 2 2 1 Apg6 BARA domain DUF3347 PF11827.8 KFY01067.1 - 1.3 9.1 5.2 2.1 8.5 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) LSM PF01423.22 KFY01071.1 - 2.2e-21 75.3 0.6 2.5e-21 75.1 0.6 1.0 1 0 0 1 1 1 1 LSM domain Thiolase_N PF00108.23 KFY01072.1 - 3.1e-95 318.4 1.9 3.1e-95 318.4 1.9 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY01072.1 - 1.4e-46 157.2 1.5 1.4e-46 157.2 1.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFY01072.1 - 9.8e-06 25.3 0.5 2.4e-05 24.0 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFY01072.1 - 0.15 11.9 2.0 1.1 9.2 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 KFY01073.1 - 5.2e-47 159.9 0.0 7.9e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFY01073.1 - 3.9e-37 127.5 9.7 7.3e-37 126.7 9.7 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFY01073.1 - 2.5e-21 75.7 0.0 6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFY01073.1 - 7.8e-18 64.3 0.0 2.4e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFY01073.1 - 2.9e-10 40.4 0.0 6.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFY01073.1 - 1.1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFY01073.1 - 4.3e-06 26.8 0.1 8.4e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFY01073.1 - 0.063 12.7 0.1 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_N PF08240.12 KFY01074.1 - 3e-27 94.7 2.4 3.7e-27 94.4 1.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KFY01074.1 - 1.5e-07 31.2 1.0 3.7e-07 29.9 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KFY01074.1 - 2.8e-06 27.3 0.0 0.00096 19.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase CPSase_sm_chain PF00988.22 KFY01082.1 - 3.6e-26 91.5 0.0 7.1e-26 90.5 0.0 1.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Leader_CPA1 PF08252.11 KFY01082.1 - 1.1e-13 50.3 0.1 1.9e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide ADH_N PF08240.12 KFY01083.1 - 1.6e-26 92.3 1.5 2.8e-26 91.5 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY01083.1 - 9.9e-16 57.9 2.0 9.1e-15 54.8 2.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFY01083.1 - 9.3e-09 35.1 2.0 3.9e-05 23.2 0.3 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFY01083.1 - 0.011 15.1 1.6 0.021 14.1 1.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFY01083.1 - 0.033 14.3 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFY01083.1 - 0.077 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KFY01083.1 - 0.12 12.7 0.3 0.48 10.7 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 KFY01089.1 - 7.6e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KFY01089.1 - 1.1e-11 44.7 0.1 1.3e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFY01089.1 - 5.1e-11 42.6 0.0 9.8e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01089.1 - 1.6e-08 35.1 0.0 4.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY01089.1 - 2.9e-07 30.5 0.0 5.6e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFY01089.1 - 4.1e-07 29.2 0.1 4.9e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KFY01089.1 - 8.7e-06 25.2 0.1 1e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFY01089.1 - 1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFY01089.1 - 1.8e-05 24.4 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFY01089.1 - 4.1e-05 24.3 0.0 7.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFY01089.1 - 0.00023 20.5 0.1 0.00034 20.0 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KFY01089.1 - 0.00053 19.8 0.1 0.00066 19.4 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KFY01089.1 - 0.00079 19.6 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 KFY01089.1 - 0.0038 17.0 0.1 0.0054 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KFY01089.1 - 0.0059 16.6 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFY01089.1 - 0.0084 15.7 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 TehB PF03848.14 KFY01089.1 - 0.014 14.8 0.2 0.02 14.3 0.2 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KFY01089.1 - 0.03 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PRMT5 PF05185.16 KFY01089.1 - 0.032 14.1 0.2 0.057 13.3 0.2 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KFY01089.1 - 0.045 14.8 0.0 0.069 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KFY01089.1 - 0.051 13.3 0.1 0.067 12.9 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 KFY01089.1 - 0.07 12.8 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 KFY01089.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Per1 PF04080.13 KFY01090.1 - 1.2e-103 346.4 7.9 1.4e-103 346.1 7.9 1.0 1 0 0 1 1 1 1 Per1-like family DEAD PF00270.29 KFY01091.1 - 5.6e-45 153.2 0.0 8.1e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY01091.1 - 1.9e-30 105.4 0.0 1.4e-29 102.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY01091.1 - 0.00037 20.5 0.0 0.00073 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 KFY01092.1 - 2e-51 174.8 0.0 2.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain MRNIP PF15749.5 KFY01092.1 - 0.17 12.6 8.6 0.5 11.1 8.6 1.8 1 0 0 1 1 1 0 MRN-interacting protein AP3D1 PF06375.11 KFY01092.1 - 2 8.6 15.6 0.86 9.8 12.4 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PBP_sp32 PF07222.12 KFY01092.1 - 3.2 7.1 7.5 17 4.8 7.5 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 PPL5 PF18168.1 KFY01092.1 - 3.9 6.7 6.5 8.7 5.5 6.5 1.5 1 0 0 1 1 1 0 Prim-pol family 5 CDC45 PF02724.14 KFY01099.1 - 3.3e-238 792.1 2.4 3.9e-237 788.6 2.4 3.0 1 1 0 1 1 1 1 CDC45-like protein Thioredoxin_12 PF18400.1 KFY01099.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain SAPS PF04499.15 KFY01099.1 - 0.54 9.0 4.9 0.21 10.3 0.7 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CSRNP_N PF16019.5 KFY01099.1 - 1.6 8.6 8.2 0.074 13.0 2.1 1.8 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus BUD22 PF09073.10 KFY01099.1 - 8.3 5.6 41.4 1.3 8.2 19.8 2.4 3 0 0 3 3 3 0 BUD22 MFS_1 PF07690.16 KFY01100.1 - 1.7e-19 70.0 29.6 4.5e-19 68.6 28.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KFY01100.1 - 0.058 13.7 0.3 0.058 13.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4231 PF14015.6 KFY01100.1 - 7.6 7.1 8.8 1e+02 3.4 2.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) adh_short PF00106.25 KFY01101.1 - 5e-31 107.7 0.0 6.7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY01101.1 - 4.4e-23 82.1 0.0 1.7e-22 80.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY01101.1 - 6.8e-08 32.6 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain RtcR PF06956.11 KFY01101.1 - 0.04 13.3 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase ATP-grasp_5 PF13549.6 KFY01101.1 - 0.059 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain Reprolysin_3 PF13582.6 KFY01102.1 - 0.0026 18.3 0.1 0.0055 17.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFY01102.1 - 0.0058 16.8 0.2 0.0082 16.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFY01102.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KFY01102.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 MAD PF05557.13 KFY01120.1 - 8.2e-58 196.3 54.1 1.8e-57 195.2 54.1 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Intimin_C PF07979.11 KFY01120.1 - 0.16 12.4 0.0 0.62 10.5 0.0 2.0 1 0 0 1 1 1 0 Intimin C-type lectin domain YqjK PF13997.6 KFY01120.1 - 0.65 10.3 3.9 2.9 8.2 0.0 3.4 3 0 0 3 3 3 0 YqjK-like protein DUF2316 PF10078.9 KFY01120.1 - 1.1 9.5 12.6 0.46 10.7 1.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) UQ_con PF00179.26 KFY01122.1 - 2.2e-09 37.1 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFY01122.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain Ccdc124 PF06244.12 KFY01123.1 - 1e-27 97.2 19.3 1e-27 97.2 19.3 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 SbsC_C PF18058.1 KFY01123.1 - 0.012 15.9 1.1 0.012 15.9 1.1 3.1 2 1 0 2 2 2 0 SbsC C-terminal domain Bud13 PF09736.9 KFY01123.1 - 0.59 10.5 24.9 1.1 9.6 12.2 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Tcp11 PF05794.13 KFY01132.1 - 1e-108 364.3 0.3 1e-108 364.3 0.3 2.3 2 0 0 2 2 2 1 T-complex protein 11 UPF0242 PF06785.11 KFY01132.1 - 3.5 7.7 5.2 8.9 6.4 5.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-B_dimeris PF09026.10 KFY01133.1 - 0.041 14.3 4.5 0.058 13.8 4.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Polyketide_cyc2 PF10604.9 KFY01134.1 - 2.4e-07 31.1 0.6 3.6e-07 30.5 0.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KFY01134.1 - 0.017 15.3 0.1 0.026 14.7 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport TcpQ PF10671.9 KFY01134.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Beta_helix PF13229.6 KFY01135.1 - 0.0028 17.5 7.3 0.024 14.5 5.0 2.2 1 1 2 3 3 3 2 Right handed beta helix region POR_N PF01855.19 KFY01135.1 - 0.73 9.5 4.4 1.1 8.9 4.4 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PAF-AH_p_II PF03403.13 KFY01136.1 - 4.7e-12 45.1 0.0 6.5e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFY01136.1 - 3.3e-08 32.8 0.0 5.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KFY01136.1 - 0.00012 22.8 1.1 0.00022 21.9 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01136.1 - 0.00036 19.9 0.1 0.0098 15.2 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KFY01136.1 - 0.00048 19.9 0.1 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KFY01136.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family PGAP1 PF07819.13 KFY01136.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 KFY01136.1 - 0.068 12.2 0.1 0.98 8.4 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Lipase_3 PF01764.25 KFY01136.1 - 0.093 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 KFY01136.1 - 0.14 11.6 0.5 1.1 8.7 0.2 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.11 KFY01137.1 - 3.9e-13 50.0 4.0 3.3e-10 40.5 0.6 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_71 PF03659.14 KFY01138.1 - 3.4e-79 266.4 0.1 4e-79 266.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 MFS_1 PF07690.16 KFY01139.1 - 4.1e-27 95.0 53.2 3.7e-15 55.7 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY01139.1 - 4e-09 35.9 21.4 5.4e-05 22.2 11.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3040 PF11239.8 KFY01141.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SET PF00856.28 KFY01142.1 - 1.3e-13 51.7 0.5 6.5e-13 49.4 0.1 2.5 3 1 0 3 3 3 1 SET domain TPR_2 PF07719.17 KFY01142.1 - 0.0009 19.2 2.3 0.16 12.2 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFY01142.1 - 0.0034 17.9 0.7 0.21 12.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY01142.1 - 0.0058 17.4 3.1 0.89 10.6 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_12 PF13087.6 KFY01143.1 - 2.4e-19 69.7 0.0 4.9e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY01143.1 - 1.5e-12 47.9 0.0 1.6e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFY01143.1 - 1e-07 31.9 0.0 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFY01143.1 - 0.0013 19.1 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFY01143.1 - 0.0061 16.3 0.2 12 5.5 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KFY01143.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zn_clus PF00172.18 KFY01144.1 - 3.6e-08 33.4 6.4 8.6e-08 32.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY01144.1 - 0.017 14.0 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Opy2 PF09463.10 KFY01144.1 - 3.2 8.1 8.7 0.25 11.7 3.7 1.8 2 0 0 2 2 2 0 Opy2 protein RGS PF00615.19 KFY01154.1 - 6.1e-12 45.9 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.19 KFY01155.1 - 2.2e-39 133.5 1.1 3.7e-39 132.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e NOG1_N PF17835.1 KFY01155.1 - 0.07 13.1 0.3 0.13 12.2 0.3 1.5 1 1 0 1 1 1 0 NOG1 N-terminal helical domain UQ_con PF00179.26 KFY01156.1 - 7.7e-48 161.7 0.0 8.9e-48 161.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFY01156.1 - 6.1e-05 22.7 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFY01156.1 - 0.00061 20.1 0.0 0.00072 19.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFY01156.1 - 0.0033 17.3 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 KFY01157.1 - 3.6e-59 200.3 0.0 5.1e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01157.1 - 1.1e-24 87.1 0.0 1.7e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KFY01157.1 - 7.1e-08 32.2 0.1 1.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like Kinase-like PF14531.6 KFY01157.1 - 6.8e-07 28.9 0.0 9.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like F-box PF00646.33 KFY01157.1 - 0.00077 19.3 1.0 0.0018 18.1 0.2 2.1 2 0 0 2 2 2 1 F-box domain APH PF01636.23 KFY01157.1 - 0.027 14.4 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KFY01157.1 - 0.04 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.9 KFY01158.1 - 2.4e-12 46.7 0.0 5.6e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 SprT-like family RRM_1 PF00076.22 KFY01159.1 - 1.1e-14 54.0 0.1 1.6e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFY01159.1 - 0.045 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Sacchrp_dh_NADP PF03435.18 KFY01160.1 - 4.1e-14 52.9 0.0 6.9e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain SCO1-SenC PF02630.14 KFY01160.1 - 0.054 13.4 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Shikimate_DH PF01488.20 KFY01160.1 - 0.072 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peroxin-13_N PF04088.13 KFY01165.1 - 6.2e-41 140.1 2.0 8e-41 139.7 2.0 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region GST_N PF02798.20 KFY01166.1 - 4.5e-10 39.7 0.0 8.4e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFY01166.1 - 1.3e-07 32.0 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFY01166.1 - 1.9e-07 31.3 0.0 4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY01166.1 - 3.8e-07 30.2 0.1 5.9e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFY01166.1 - 0.00011 22.3 0.3 0.0011 19.2 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin GST_C_2 PF13410.6 KFY01166.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFY01166.1 - 0.012 15.8 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3344 PF11824.8 KFY01166.1 - 0.025 14.2 0.1 0.031 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) COesterase PF00135.28 KFY01167.1 - 1.3e-86 291.5 0.0 1.7e-86 291.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY01167.1 - 0.022 14.6 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_3 PF13302.7 KFY01168.1 - 3.7e-32 111.9 0.0 4.3e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY01168.1 - 8.6e-06 26.0 0.0 1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KFY01168.1 - 9.5e-06 25.4 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY01168.1 - 0.0014 18.6 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein HMG-CoA_red PF00368.18 KFY01169.1 - 1.3e-140 468.7 4.5 1.7e-140 468.2 4.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KFY01169.1 - 2.4e-48 163.9 0.0 4.3e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KFY01169.1 - 7.5e-13 48.6 4.4 5e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFY01169.1 - 3.2e-07 28.9 0.9 5.2e-07 28.2 0.9 1.3 1 0 0 1 1 1 1 Patched family RNR_inhib PF08591.10 KFY01172.1 - 1.9e-30 106.3 0.4 3.2e-30 105.6 0.1 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Kelch_3 PF13415.6 KFY01173.1 - 2.3e-27 94.7 10.2 4.4e-07 30.0 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFY01173.1 - 2.3e-21 75.5 14.7 1.8e-12 47.0 0.1 7.5 6 2 1 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFY01173.1 - 6.6e-13 48.4 3.4 0.0024 18.1 0.1 5.7 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KFY01173.1 - 5.9e-09 35.4 6.1 0.68 9.6 0.0 6.9 7 2 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 KFY01173.1 - 1e-07 31.6 6.7 1.7 8.8 0.4 6.6 6 2 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KFY01173.1 - 1.9e-07 30.9 0.0 0.16 12.0 0.1 5.7 6 0 0 6 6 6 2 Kelch motif HSP70 PF00012.20 KFY01174.1 - 1.5e-80 271.1 2.6 1.5e-80 271.1 2.6 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFY01174.1 - 9.7e-11 41.0 1.3 9.9e-11 41.0 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein KH_6 PF15985.5 KFY01175.1 - 1.6e-18 66.7 0.1 3.1e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KFY01175.1 - 1.8e-18 66.2 0.8 5e-18 64.8 0.6 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Cyt-b5 PF00173.28 KFY01181.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1993 PF09351.10 KFY01182.1 - 7.3e-52 175.8 0.0 8.1e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) FliG_M PF14841.6 KFY01182.1 - 0.092 13.0 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 FliG middle domain RTA1 PF04479.13 KFY01183.1 - 5.1e-48 163.4 21.3 4.3e-31 108.1 4.5 2.9 1 1 2 3 3 3 2 RTA1 like protein MFS_1 PF07690.16 KFY01185.1 - 7e-48 163.3 54.2 7e-48 163.3 54.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY01185.1 - 2.4e-19 69.2 12.7 2.4e-19 69.2 12.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFY01185.1 - 3.4e-17 62.4 5.6 3.4e-17 62.4 5.6 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter ADH_zinc_N PF00107.26 KFY01186.1 - 3.2e-09 36.9 0.0 5.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01186.1 - 7.3e-06 27.1 0.0 1.3e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KFY01187.1 - 5.4e-07 29.6 5.6 9.6e-07 28.8 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.12 KFY01187.1 - 0.026 14.6 1.0 0.036 14.1 0.2 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ketoacyl-synt PF00109.26 KFY01188.1 - 5e-74 249.1 0.0 1.3e-73 247.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KFY01188.1 - 1.1e-69 235.1 0.1 3.1e-69 233.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KFY01188.1 - 2.9e-69 233.9 0.9 4.4e-69 233.3 0.9 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KFY01188.1 - 2.5e-53 180.7 0.9 1.4e-51 175.0 0.0 3.7 5 0 0 5 5 3 1 KR domain PS-DH PF14765.6 KFY01188.1 - 9.3e-48 163.0 0.0 2e-47 161.9 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFY01188.1 - 1.4e-44 153.0 0.2 2.7e-44 152.0 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY01188.1 - 8e-32 109.7 0.2 4.6e-31 107.3 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFY01188.1 - 1.4e-28 99.8 0.0 6.2e-22 78.0 0.0 2.6 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.25 KFY01188.1 - 6.7e-20 71.2 0.7 5.2e-10 39.5 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KFY01188.1 - 1.2e-19 70.8 0.0 5.7e-19 68.7 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KFY01188.1 - 4.1e-19 69.0 0.0 1.2e-13 51.1 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KFY01188.1 - 8.9e-14 51.6 0.0 2.3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY01188.1 - 3.8e-13 50.0 0.0 2.2e-12 47.5 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFY01188.1 - 6.4e-13 49.1 0.0 2.2e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KFY01188.1 - 6e-12 46.1 0.0 2.4e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFY01188.1 - 4.9e-10 39.2 0.1 2.6e-09 36.8 0.0 2.4 3 0 0 3 3 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KFY01188.1 - 1.7e-08 34.4 0.0 5.8e-08 32.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KFY01188.1 - 2.1e-08 33.5 0.0 3.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFY01188.1 - 2.9e-08 33.5 0.0 0.0011 18.5 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 KFY01188.1 - 2.3e-07 30.4 0.0 1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KFY01188.1 - 4e-05 23.1 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KFY01188.1 - 0.0001 22.0 0.0 0.00024 20.7 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFY01188.1 - 0.0036 17.2 0.0 0.6 10.0 0.0 2.9 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 KFY01188.1 - 0.026 15.1 0.0 3.3 8.4 0.0 3.6 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_16 PF10294.9 KFY01188.1 - 0.029 14.1 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Lysine methyltransferase DREV PF05219.12 KFY01188.1 - 0.068 12.3 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Ribosomal_60s PF00428.19 KFY01188.1 - 6.9 7.3 6.0 1 10.0 1.0 2.2 2 0 0 2 2 1 0 60s Acidic ribosomal protein CDP-OH_P_transf PF01066.21 KFY01191.1 - 4.9e-17 62.5 0.1 4.9e-17 62.5 0.1 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF5313 PF17240.2 KFY01191.1 - 0.3 11.5 1.3 5.8 7.4 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Adaptin_N PF01602.20 KFY01192.1 - 9.9e-110 367.5 0.3 1.3e-109 367.2 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFY01192.1 - 1e-58 197.8 1.5 2e-58 196.8 1.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFY01192.1 - 3.4e-35 120.7 0.1 8.5e-35 119.4 0.1 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFY01192.1 - 8.9e-19 67.7 0.4 2.2e-12 47.2 0.0 5.4 2 1 3 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KFY01192.1 - 2.3e-06 27.8 10.9 0.053 13.6 0.1 4.9 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFY01192.1 - 0.0024 18.4 0.2 4.5 8.2 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 KFY01192.1 - 0.0078 15.8 1.0 0.1 12.2 0.1 2.7 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 KFY01192.1 - 0.024 14.9 8.1 1.7 9.1 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat MRP-S35 PF10246.9 KFY01192.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 DUF5010 PF16402.5 KFY01192.1 - 0.077 11.8 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) Pkinase PF00069.25 KFY01193.1 - 3.2e-26 92.3 0.0 4.1e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01193.1 - 8.8e-14 51.4 0.0 1.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY01193.1 - 4.4e-09 35.6 0.0 7.5e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFY01193.1 - 0.00023 21.2 0.0 0.0016 18.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family APS_kinase PF01583.20 KFY01194.1 - 8.3e-57 191.5 0.1 1.1e-56 191.0 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 KFY01194.1 - 1.3e-23 83.6 0.0 2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase CPT PF07931.12 KFY01194.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein YjeF_N PF03853.15 KFY01194.1 - 0.14 12.1 0.1 21 5.0 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus AAA_18 PF13238.6 KFY01194.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 KFY01195.1 - 1.1e-28 99.8 0.1 1.7e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01195.1 - 4e-19 70.0 0.0 9.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY01195.1 - 0.00031 20.6 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KFY01195.1 - 0.013 15.0 0.8 0.021 14.3 0.8 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 KFY01195.1 - 0.015 15.0 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KFY01195.1 - 0.031 13.6 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIS_2 PF13580.6 KFY01195.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 SIS domain DAGK_cat PF00781.24 KFY01195.1 - 0.098 12.3 0.2 0.26 10.9 0.1 1.7 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain ADH_N_2 PF16884.5 KFY01195.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase tRNA-synt_2 PF00152.20 KFY01196.1 - 1.3e-58 198.6 0.0 1.8e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFY01196.1 - 0.0018 18.2 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_P83 PF05262.11 KFY01196.1 - 0.31 9.5 6.2 0.47 8.9 6.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_16 PF10294.9 KFY01201.1 - 8.7e-16 58.1 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFY01201.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KFY01201.1 - 0.00015 22.4 0.0 0.0006 20.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY01201.1 - 0.00039 20.3 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01201.1 - 0.00055 20.5 0.2 0.0033 18.0 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 KFY01201.1 - 0.0068 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 KFY01201.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 KFY01201.1 - 0.047 14.4 0.1 0.1 13.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFY01201.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ribonuc_L-PSP PF01042.21 KFY01202.1 - 4.3e-20 71.9 0.0 5.2e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.24 KFY01203.1 - 3e-11 43.5 0.1 3.9e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2427 PF10348.9 KFY01204.1 - 2.9e-05 23.8 4.4 0.02 14.6 0.8 3.5 3 1 0 3 3 3 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KFY01204.1 - 3.9e-05 23.8 8.8 0.0001 22.4 8.8 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PTPLA PF04387.14 KFY01204.1 - 0.068 12.9 0.9 0.17 11.6 0.4 2.0 1 1 1 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA DUF485 PF04341.12 KFY01204.1 - 5.6 7.0 8.0 6 6.9 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function, DUF485 Mito_carr PF00153.27 KFY01205.1 - 1.1e-24 86.2 6.0 2.6e-11 43.3 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein Copper-bind PF00127.20 KFY01205.1 - 0.013 16.0 0.1 0.08 13.4 0.1 2.2 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family E1-E2_ATPase PF00122.20 KFY01207.1 - 1e-47 162.0 4.1 1e-47 162.0 4.1 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFY01207.1 - 6.3e-18 65.8 0.0 1.7e-17 64.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFY01207.1 - 1.2e-11 44.1 0.0 2.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFY01207.1 - 0.0025 17.6 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY01207.1 - 0.009 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) SPATIAL PF15256.6 KFY01207.1 - 0.016 15.6 0.1 0.027 14.8 0.1 1.3 1 0 0 1 1 1 0 SPATIAL DUF2613 PF11021.8 KFY01207.1 - 7.5 6.7 8.7 7.5 6.7 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Dicty_CAR PF05462.11 KFY01217.1 - 3.8e-06 26.3 3.9 3.8e-06 26.3 3.9 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFY01217.1 - 0.012 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFY01217.1 - 0.025 14.3 5.5 0.043 13.6 4.5 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF5367 PF17329.2 KFY01217.1 - 4 7.6 9.3 1.4 9.1 0.1 3.4 2 1 2 4 4 4 0 Family of unknown function (DUF5367) ATP-synt_C PF00137.21 KFY01218.1 - 2e-55 185.0 69.7 6.2e-19 68.1 16.6 4.1 4 0 0 4 4 4 4 ATP synthase subunit C Fungal_trans_2 PF11951.8 KFY01219.1 - 9.4e-07 28.0 0.9 1.3e-06 27.5 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyoxalase_6 PF18029.1 KFY01220.1 - 0.00074 20.3 0.2 0.0011 19.7 0.2 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KFY01220.1 - 0.0016 18.6 0.1 0.0052 17.0 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Zn_clus PF00172.18 KFY01221.1 - 4.2e-05 23.6 12.9 6.5e-05 23.0 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFY01222.1 - 6.7e-23 81.2 25.1 6.7e-23 81.2 25.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GPR_Gpa2_C PF11970.8 KFY01222.1 - 1 9.5 4.6 3.3 7.8 4.6 1.9 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term PI3_PI4_kinase PF00454.27 KFY01226.1 - 4e-37 128.4 0.0 2.7e-36 125.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KFY01226.1 - 9.1e-19 67.2 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KFY01226.1 - 0.039 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase_Tyr PF07714.17 KFY01227.1 - 2.9e-19 69.4 0.0 1.3e-17 64.0 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFY01227.1 - 8e-17 61.5 0.0 2.1e-16 60.1 0.0 1.6 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KFY01227.1 - 8.3e-13 47.9 15.4 1.2e-06 28.2 1.1 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFY01227.1 - 1.2e-09 38.3 0.8 0.098 13.1 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Kdo PF06293.14 KFY01227.1 - 3.3e-07 29.9 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFY01227.1 - 0.0001 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFY01227.1 - 0.0016 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_5 PF13306.6 KFY01227.1 - 0.011 15.6 0.1 1.1 9.3 0.1 2.6 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) RIO1 PF01163.22 KFY01227.1 - 0.032 13.8 0.1 0.072 12.7 0.1 1.5 2 0 0 2 2 2 0 RIO1 family LRR_1 PF00560.33 KFY01227.1 - 0.095 13.3 10.2 0.45 11.3 0.5 4.5 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 KFY01227.1 - 0.24 10.9 0.2 24 4.4 0.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeat TMEM131_like PF12371.8 KFY01229.1 - 0.027 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 131-like UPF0242 PF06785.11 KFY01231.1 - 0.00037 20.7 6.0 0.13 12.3 3.9 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus GCSF PF16647.5 KFY01231.1 - 0.00047 20.0 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 Granulocyte colony-stimulating factor Phage_Mu_Gam PF07352.12 KFY01231.1 - 0.01 15.8 4.2 0.01 15.8 4.2 4.0 4 1 1 5 5 5 1 Bacteriophage Mu Gam like protein CysG_dimeriser PF10414.9 KFY01231.1 - 0.92 9.3 4.1 11 5.8 0.1 2.8 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Fib_alpha PF08702.10 KFY01231.1 - 1.3 9.2 7.5 3.1 8.0 2.2 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 KFY01231.1 - 2.4 8.8 9.2 8.6 7.0 5.3 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal V-ATPase_G PF03179.15 KFY01231.1 - 5.4 7.6 13.8 0.43 11.1 3.7 2.7 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF1640 PF07798.11 KFY01231.1 - 7.4 6.6 12.2 4.9 7.2 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) TPR_1 PF00515.28 KFY01232.1 - 1.2e-30 104.1 22.2 4.8e-07 29.3 0.1 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFY01232.1 - 2.9e-29 98.8 31.2 2.7e-05 23.9 0.2 9.5 11 0 0 11 11 9 8 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY01232.1 - 7.3e-29 99.8 21.3 1e-23 83.4 0.9 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFY01232.1 - 2.2e-20 71.1 16.5 5.8e-05 23.0 0.3 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KFY01232.1 - 3.6e-15 56.0 22.9 0.0037 17.5 0.6 8.6 6 3 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFY01232.1 - 4.7e-15 55.9 14.1 0.00019 21.9 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFY01232.1 - 8.1e-15 54.3 13.3 0.048 14.5 0.1 9.4 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFY01232.1 - 1.2e-13 50.4 17.0 0.0068 16.1 3.0 8.6 8 2 2 10 10 10 4 TPR repeat TPR_16 PF13432.6 KFY01232.1 - 2.3e-13 50.5 17.3 2.3e-06 28.2 0.6 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY01232.1 - 5.7e-13 47.9 9.7 0.0096 15.9 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFY01232.1 - 2.9e-10 39.8 11.9 3.2 8.3 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFY01232.1 - 1.1e-07 31.9 4.4 2.9 8.1 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFY01232.1 - 2e-06 28.1 19.5 7.2 7.5 0.1 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFY01232.1 - 0.0016 18.7 3.4 16 5.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFY01232.1 - 0.73 9.8 13.3 16 5.5 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 KFY01233.1 - 4.7e-51 172.9 0.0 5.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CENP-T_C PF15511.6 KFY01234.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFY01234.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFY01234.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KFY01234.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFY01234.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KFY01234.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFY01234.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFY01234.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KFY01234.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region CTK3 PF12243.8 KFY01235.1 - 1.9e-46 157.1 0.3 2.6e-46 156.6 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KFY01235.1 - 7.2e-20 70.9 5.0 7.2e-20 70.9 5.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus P5CR_dimer PF14748.6 KFY01236.1 - 1.6e-34 118.2 1.4 3.2e-34 117.3 1.0 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFY01236.1 - 6.2e-10 39.5 0.5 1e-08 35.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CAP160 PF07918.11 KFY01236.1 - 0.039 13.7 0.3 0.077 12.8 0.3 1.4 1 0 0 1 1 1 0 CAP160 repeat Hat1_N PF10394.9 KFY01237.1 - 1.1e-48 165.5 0.0 2e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Glyco_hydro_16 PF00722.21 KFY01260.1 - 2e-41 141.4 1.5 3.1e-41 140.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PP2C PF00481.21 KFY01261.1 - 2.2e-53 181.5 0.0 4e-53 180.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KFY01261.1 - 2.9e-41 139.1 46.2 2e-08 33.8 0.7 9.8 5 3 4 10 10 10 9 Leucine rich repeat Guanylate_cyc PF00211.20 KFY01261.1 - 5.7e-28 97.8 0.0 3.3e-27 95.3 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KFY01261.1 - 6.1e-28 96.4 60.7 0.0014 19.0 0.2 11.7 6 3 5 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFY01261.1 - 5.6e-08 32.3 45.6 4.2 8.3 0.0 15.4 17 0 0 17 17 17 3 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.11 KFY01261.1 - 4.5e-06 26.3 1.8 6.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 KFY01261.1 - 6.3e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 KFY01261.1 - 1.1e-05 25.0 19.3 0.00016 21.2 0.3 5.1 4 1 1 5 5 5 2 Leucine-rich repeat LRR_5 PF13306.6 KFY01261.1 - 0.0038 17.2 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Sugar_tr PF00083.24 KFY01274.1 - 7.2e-17 61.4 5.1 7.8e-17 61.3 5.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3328 PF11807.8 KFY01281.1 - 0.039 13.7 1.7 1 9.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DNA_pol_phi PF04931.13 KFY01281.1 - 0.25 9.4 6.7 0.31 9.1 6.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KFY01282.1 - 8e-43 146.7 47.3 2.2e-42 145.3 43.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY01282.1 - 1.2e-15 57.4 7.2 1.2e-15 57.4 7.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFY01282.1 - 1.2e-05 24.0 16.4 1.2e-05 24.0 16.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 KFY01282.1 - 9.2 6.6 7.7 3.3 8.0 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) GATase PF00117.28 KFY01283.1 - 5.1e-13 49.2 0.0 7.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFY01283.1 - 0.011 15.5 2.1 4.2 7.1 2.1 3.0 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.14 KFY01283.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Senescence PF06911.12 KFY01284.1 - 1.1e-55 188.8 8.0 1.6e-55 188.3 8.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Rho_GDI PF02115.17 KFY01285.1 - 6e-65 218.7 0.7 6.6e-65 218.5 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 KFY01286.1 - 1.2e-37 130.5 0.4 1.5e-37 130.1 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFY01286.1 - 0.02 15.3 0.3 0.054 13.9 0.3 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KFY01286.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 KFY01287.1 - 0.0017 18.3 2.8 0.0033 17.4 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Adaptin_N PF01602.20 KFY01288.1 - 1.7e-104 350.3 0.0 2e-104 350.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KFY01288.1 - 5.1e-14 52.4 0.6 2.5e-05 24.6 0.0 5.0 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KFY01288.1 - 1.5e-13 51.1 0.0 2.3e-12 47.3 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFY01288.1 - 6.8e-10 38.3 0.0 0.053 13.8 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KFY01288.1 - 0.0005 20.5 1.1 0.1 13.1 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat VHS PF00790.19 KFY01288.1 - 0.03 14.2 0.5 63 3.4 0.0 4.0 4 0 0 4 4 4 0 VHS domain Cohesin_HEAT PF12765.7 KFY01288.1 - 0.069 13.5 0.0 3.5 8.0 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CRISPR_Cse2 PF09485.10 KFY01288.1 - 0.1 13.1 0.8 1.9 9.0 0.4 3.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Cnd3 PF12719.7 KFY01288.1 - 0.12 11.6 0.2 0.66 9.1 0.1 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Na_Ca_ex_C PF16494.5 KFY01288.1 - 1.7 9.1 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Pes-10 PF07149.11 KFY01289.1 - 0.21 10.6 0.3 0.27 10.2 0.3 1.1 1 0 0 1 1 1 0 Pes-10 UCR_TM PF02921.14 KFY01290.1 - 1.4e-11 44.7 0.7 1.4e-11 44.7 0.7 1.9 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFY01290.1 - 2.7e-11 43.2 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pectinesterase PF01095.19 KFY01291.1 - 2.8e-31 108.3 0.3 4e-24 84.9 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase Alpha-amylase PF00128.24 KFY01292.1 - 2.8e-113 378.9 1.0 3.4e-113 378.6 0.2 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFY01292.1 - 0.00019 21.5 0.1 0.00066 19.7 0.0 2.0 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFY01292.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 KFY01292.1 - 0.045 13.5 0.2 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase C-terminal domain Cyc-maltodext_C PF10438.9 KFY01292.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Sugar_tr PF00083.24 KFY01293.1 - 4.1e-90 302.8 23.7 4.6e-90 302.6 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01293.1 - 3.4e-16 59.1 35.8 4.7e-16 58.7 29.0 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFY01293.1 - 1.9e-06 27.5 2.7 3.9e-06 26.4 2.7 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 KFY01294.1 - 4.7e-12 45.5 2.3 7.5e-12 44.8 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01294.1 - 2.7e-06 27.4 11.7 6.2e-06 26.2 11.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2653 PF10850.8 KFY01294.1 - 0.056 13.7 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) Glyco_hydro_28 PF00295.17 KFY01295.1 - 1.9e-48 165.2 8.3 2.7e-48 164.7 8.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFY01295.1 - 0.046 13.6 7.2 0.077 12.8 7.2 1.4 1 0 0 1 1 1 0 Right handed beta helix region Glyco_hydro_28 PF00295.17 KFY01296.1 - 7.3e-42 143.6 16.0 9.1e-42 143.2 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.8 KFY01296.1 - 0.00024 20.7 0.2 0.00076 19.1 0.0 2.0 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.19 KFY01297.1 - 1.6e-48 165.0 9.0 2e-48 164.6 9.0 1.0 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.24 KFY01298.1 - 4.9e-89 299.3 22.4 2.3e-83 280.6 14.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFY01298.1 - 5.4e-30 104.5 13.0 5.4e-30 104.5 13.0 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 KFY01298.1 - 0.27 10.2 11.3 0.029 13.4 6.0 2.0 2 0 0 2 2 2 0 PUCC protein Cpn60_TCP1 PF00118.24 KFY01299.1 - 2.7e-152 507.8 18.0 3.1e-152 507.6 18.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HGTP_anticodon PF03129.20 KFY01300.1 - 4.3e-19 68.5 0.0 1e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFY01300.1 - 3.1e-18 66.4 0.0 7.4e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 KFY01300.1 - 6.5e-17 61.5 1.3 1.8e-16 60.1 1.3 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal GTP-bdg_M PF16360.5 KFY01302.1 - 0.012 16.2 1.4 0.03 14.9 1.4 1.9 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Ribosomal_L20 PF00453.18 KFY01302.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2048 PF09752.9 KFY01302.1 - 0.026 13.6 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 ALG3 PF05208.13 KFY01303.1 - 9.1e-148 492.4 13.8 1e-147 492.3 13.8 1.0 1 0 0 1 1 1 1 ALG3 protein Adeno_E3_CR2 PF02439.15 KFY01303.1 - 0.065 13.0 2.4 0.17 11.7 0.3 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 eIF-1a PF01176.19 KFY01304.1 - 5.7e-20 70.9 0.1 1.5e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 BCIP PF13862.6 KFY01306.1 - 2.7e-71 239.6 0.3 3.3e-71 239.3 0.3 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PMT_4TMC PF16192.5 KFY01321.1 - 4.8e-33 114.4 2.5 5.6e-33 114.2 2.5 1.1 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase TauD PF02668.16 KFY01322.1 - 7e-49 167.0 0.3 1e-48 166.5 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFY01322.1 - 3.3e-05 24.5 0.0 8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFY01322.1 - 0.014 14.6 0.1 0.058 12.5 0.0 1.9 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.6 KFY01322.1 - 0.038 14.9 1.7 0.15 13.0 1.7 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 KFY01323.1 - 1.2e-63 211.0 3.5 1.7e-21 75.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFY01323.1 - 0.061 12.5 1.9 2 7.5 0.1 3.1 3 1 1 4 4 4 0 Gammaproteobacterial serine protease HicA_toxin PF07927.12 KFY01323.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, TFIID_30kDa PF03540.13 KFY01324.1 - 1.5e-25 88.8 0.2 2.2e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KFY01324.1 - 4.2 8.0 6.1 1.1 9.9 2.1 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF962 PF06127.11 KFY01326.1 - 2.7e-24 85.1 0.0 4.2e-24 84.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3270 PF11674.8 KFY01326.1 - 0.11 12.6 0.6 0.28 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) SHS2_Rpb7-N PF03876.17 KFY01327.1 - 1.4e-15 57.4 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFY01327.1 - 9.3e-10 38.7 0.0 2.1e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KFY01327.1 - 0.0029 17.8 0.1 0.0051 17.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 GEN1_C PF18380.1 KFY01328.1 - 1.8e-26 93.1 0.1 5.3e-26 91.5 0.1 1.9 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KFY01328.1 - 3e-22 78.8 0.0 5.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFY01328.1 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFY01328.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing DUF4692 PF15763.5 KFY01328.1 - 1.1 9.7 13.2 0.2 12.1 3.2 2.3 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Actin PF00022.19 KFY01329.1 - 1.4e-21 76.6 0.0 6.9e-20 71.0 0.0 3.0 2 1 0 2 2 2 2 Actin ATP-synt_ab PF00006.25 KFY01330.1 - 5.8e-73 245.1 0.0 8.8e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFY01330.1 - 1.5e-46 157.8 0.3 2.5e-46 157.1 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFY01330.1 - 3.7e-15 56.2 2.9 9.1e-15 54.9 2.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 KFY01330.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GAF PF01590.26 KFY01331.1 - 0.0056 17.3 0.0 0.027 15.1 0.0 2.1 2 0 0 2 2 2 1 GAF domain Prok-E2_B PF14461.6 KFY01331.1 - 0.043 13.5 0.9 25 4.6 0.0 3.2 2 1 1 3 3 3 0 Prokaryotic E2 family B MGC-24 PF05283.11 KFY01331.1 - 2.2 8.7 9.8 0.79 10.2 0.0 3.0 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_L27e PF01777.18 KFY01332.1 - 1.2e-37 128.2 3.4 1.5e-37 127.8 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFY01332.1 - 0.008 16.1 2.3 0.0092 15.9 0.5 2.1 2 0 0 2 2 2 1 KOW motif DUF826 PF05696.11 KFY01332.1 - 0.12 12.5 0.3 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF826) ECM11 PF15463.6 KFY01332.1 - 0.24 12.0 1.7 0.4 11.2 0.2 1.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 Apolipoprotein PF01442.18 KFY01333.1 - 0.00019 21.4 1.1 0.00019 21.4 1.1 8.0 4 2 4 8 8 8 1 Apolipoprotein A1/A4/E domain Scm3 PF10384.9 KFY01333.1 - 0.061 13.1 1.1 0.22 11.3 1.1 2.0 1 0 0 1 1 1 0 Centromere protein Scm3 Peroxin-13_N PF04088.13 KFY01333.1 - 0.35 11.1 4.4 7.6 6.8 0.1 3.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF3289 PF11692.8 KFY01333.1 - 0.99 8.9 5.1 0.63 9.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3289) DUF4854 PF16146.5 KFY01333.1 - 1.6 9.1 7.7 3.2 8.1 0.1 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4854) Tup_N PF08581.10 KFY01333.1 - 4.8 7.6 31.1 0.66 10.3 0.1 7.4 8 0 0 8 8 8 0 Tup N-terminal Gp-FAR-1 PF05823.12 KFY01333.1 - 5.2 7.4 15.1 0.52 10.7 1.0 5.2 5 2 1 6 6 6 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HALZ PF02183.18 KFY01333.1 - 5.7 7.3 9.8 0.24 11.7 0.6 3.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper Abhydrolase_6 PF12697.7 KFY01334.1 - 5.1e-19 69.8 0.1 6.7e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY01334.1 - 5.5e-11 42.6 0.0 1.4e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY01334.1 - 1.2e-09 37.8 0.0 1.2e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Allantoicase PF03561.15 KFY01335.1 - 4.3e-85 282.9 0.2 9e-46 155.4 0.1 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 KFY01335.1 - 0.013 15.6 0.0 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 F5/8 type C domain Arginosuc_synth PF00764.19 KFY01337.1 - 8e-152 506.0 0.0 9.2e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFY01337.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC F-box-like PF12937.7 KFY01338.1 - 3.5e-05 23.6 0.5 9.4e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY01338.1 - 0.00036 20.3 0.1 0.00036 20.3 0.1 2.3 3 0 0 3 3 3 1 F-box domain DUF4524 PF15025.6 KFY01338.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Cytochrome_C7 PF14522.6 KFY01338.1 - 0.55 10.3 4.0 2.2e+02 1.9 6.2 3.3 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 KFY01338.1 - 1.9 9.0 6.6 41 4.8 2.2 3.0 1 1 0 2 2 2 0 CHY zinc finger PHD_2 PF13831.6 KFY01338.1 - 9.6 5.9 9.0 47 3.7 0.0 3.6 4 0 0 4 4 4 0 PHD-finger F-box PF00646.33 KFY01339.1 - 2.6e-05 24.0 0.0 2.6e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFY01339.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.8 2 0 0 2 2 2 0 F-box-like Aldedh PF00171.22 KFY01340.1 - 6.6e-152 506.2 0.9 8.6e-152 505.8 0.9 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box PF00646.33 KFY01340.1 - 9.4e-08 31.8 0.7 4.5e-07 29.6 0.0 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFY01340.1 - 0.0023 17.8 0.2 0.0078 16.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like DUF1487 PF07368.11 KFY01340.1 - 0.047 13.1 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) OmdA PF13376.6 KFY01340.1 - 0.16 12.0 0.5 0.38 10.8 0.5 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated RTP1_C1 PF10363.9 KFY01341.1 - 1.3e-25 89.7 0.0 5.8e-25 87.7 0.0 2.2 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KFY01341.1 - 1.1e-06 28.2 0.2 3e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DASH_Dad3 PF08656.10 KFY01342.1 - 3.4e-31 107.2 0.5 4.3e-31 106.8 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 KFY01343.1 - 2.8e-21 74.7 0.0 5.9e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFY01343.1 - 2.2e-18 66.0 0.3 4.4e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 KFY01344.1 - 3.2e-11 42.8 0.0 1.7e-09 37.1 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KFY01344.1 - 3.3e-06 26.8 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KFY01344.1 - 0.00039 21.1 0.0 0.00095 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFY01344.1 - 0.003 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFY01344.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFY01344.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UNC45-central PF11701.8 KFY01345.1 - 9.6e-52 175.0 0.1 3e-48 163.6 0.0 4.1 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KFY01345.1 - 0.0012 18.9 20.6 0.31 11.2 0.0 8.1 8 1 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 KFY01345.1 - 0.4 11.1 18.2 1.7 9.1 2.6 5.3 4 3 3 7 7 7 0 HEAT repeats HEAT_EZ PF13513.6 KFY01345.1 - 8.7 7.0 12.9 32 5.2 0.1 6.1 7 0 0 7 7 7 0 HEAT-like repeat Tfb4 PF03850.14 KFY01346.1 - 4e-105 351.3 0.0 4.6e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 ADH_N PF08240.12 KFY01347.1 - 2.3e-28 98.3 1.1 3.8e-28 97.6 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY01347.1 - 1.6e-24 86.3 0.1 2.9e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY01347.1 - 0.0071 15.7 0.2 0.012 15.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFY01347.1 - 0.03 13.6 0.5 0.05 12.9 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KFY01347.1 - 0.098 12.1 0.6 0.19 11.2 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glucokinase PF02685.16 KFY01347.1 - 0.11 11.5 0.5 0.2 10.6 0.5 1.3 1 0 0 1 1 1 0 Glucokinase Actin PF00022.19 KFY01349.1 - 4.2e-87 292.4 0.0 9.9e-85 284.6 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFY01349.1 - 0.022 13.6 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 KFY01350.1 - 3.6e-44 151.0 0.5 2.7e-27 95.6 0.0 2.4 2 0 0 2 2 2 2 Asparaginase Mtc PF03820.17 KFY01364.1 - 2.9e-67 227.0 0.5 3.2e-67 226.8 0.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 KFY01365.1 - 1.2e-50 172.4 0.0 6.3e-50 170.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01365.1 - 5.4e-21 75.0 0.0 3.7e-20 72.3 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase DUF1206 PF06724.11 KFY01383.1 - 0.68 10.1 6.1 0.8 9.8 0.9 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RSN1_7TM PF02714.15 KFY01387.1 - 1.2e-25 90.4 2.8 1.8e-25 89.8 2.8 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KFY01387.1 - 5.6e-12 45.7 0.0 8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Mgr1 PF08602.10 KFY01387.1 - 0.22 10.3 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit FtsX PF02687.21 KFY01387.1 - 3.2 8.3 8.0 7.1 7.2 8.0 1.7 1 1 0 1 1 1 0 FtsX-like permease family EcoRI PF02963.16 KFY01388.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRI FMN_red PF03358.15 KFY01399.1 - 1.5e-23 83.3 0.0 2.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFY01399.1 - 4.8e-07 29.7 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Zn_clus PF00172.18 KFY01400.1 - 4.9e-07 29.8 11.5 1.2e-06 28.5 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Avl9 PF09794.9 KFY01401.1 - 3.8e-145 483.3 0.0 5.3e-145 482.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 End3 PF12761.7 KFY01401.1 - 2.8e-77 259.4 0.5 5.2e-77 258.5 0.5 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KFY01401.1 - 3.4e-51 171.5 0.0 3.2e-49 165.2 0.1 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFY01401.1 - 6.8e-07 28.4 0.3 6.8e-07 28.4 0.3 2.6 3 0 0 3 3 3 1 EF hand DUF2347 PF09804.9 KFY01401.1 - 7e-07 29.1 0.1 2.1e-05 24.3 0.1 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) EF-hand_7 PF13499.6 KFY01401.1 - 6e-06 26.6 0.1 4.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair SPA PF08616.10 KFY01401.1 - 8.8e-06 25.7 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis EF-hand_8 PF13833.6 KFY01401.1 - 0.00017 21.4 3.9 0.00019 21.2 0.1 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KFY01401.1 - 0.00049 19.8 0.6 0.0029 17.4 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFY01401.1 - 0.024 14.1 0.1 0.1 12.1 0.1 2.1 1 0 0 1 1 1 0 EF hand Spc7 PF08317.11 KFY01401.1 - 0.63 8.9 5.8 1.6 7.6 5.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DEADboxA PF12343.8 KFY01403.1 - 0.034 14.7 2.6 0.087 13.4 2.6 1.7 1 0 0 1 1 1 0 Cold shock protein DEAD box A Spc24 PF08286.11 KFY01404.1 - 5.2e-34 116.6 5.2 1.3e-32 112.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KFY01404.1 - 0.00031 20.7 4.5 0.17 11.9 0.2 2.3 2 0 0 2 2 2 2 Prefoldin subunit Lipoprotein_16 PF03923.13 KFY01404.1 - 0.002 17.8 1.7 0.0032 17.1 1.1 1.6 2 0 0 2 2 2 1 Uncharacterized lipoprotein FlaC_arch PF05377.11 KFY01404.1 - 0.018 15.5 4.9 1 9.8 0.4 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KFY01404.1 - 0.029 13.0 2.6 0.037 12.7 2.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 KFY01404.1 - 0.058 13.9 11.3 0.082 13.4 11.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1635 PF07795.11 KFY01404.1 - 0.09 12.6 4.8 0.11 12.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Med30 PF11315.8 KFY01404.1 - 0.093 12.9 3.6 0.14 12.4 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 Troponin PF00992.20 KFY01404.1 - 0.11 12.8 3.9 0.18 12.1 3.9 1.3 1 0 0 1 1 1 0 Troponin TPR_MLP1_2 PF07926.12 KFY01404.1 - 0.13 12.3 10.6 0.45 10.6 10.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 KFY01404.1 - 1.5 8.8 4.6 1.5 8.9 1.8 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein Nup54 PF13874.6 KFY01404.1 - 2.8 8.0 9.7 6.9 6.8 9.7 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.11 KFY01404.1 - 4.1 8.0 9.8 3.6 8.2 2.8 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Uso1_p115_C PF04871.13 KFY01404.1 - 4.5 7.7 11.3 20 5.6 11.2 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fis1_TPR_C PF14853.6 KFY01405.1 - 1.2e-23 82.9 0.5 2.6e-23 81.8 0.5 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFY01405.1 - 1.6e-16 59.6 0.1 3.3e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 KFY01405.1 - 2.4e-13 50.2 15.6 3.1e-13 49.8 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFY01405.1 - 1.5e-09 37.6 8.2 5.1e-08 32.7 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFY01405.1 - 2.1e-09 37.0 2.9 2.1e-09 37.0 2.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFY01405.1 - 8.3e-09 35.1 6.3 8.3e-09 35.1 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFY01405.1 - 3.8e-07 30.3 5.2 3.8e-07 30.3 5.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFY01405.1 - 2e-06 27.6 3.1 2e-06 27.6 3.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFY01405.1 - 5.9e-06 26.1 14.4 2.4e-05 24.1 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY01405.1 - 3.8e-05 23.6 1.9 3.8e-05 23.6 1.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger HypA PF01155.19 KFY01405.1 - 0.00015 21.8 3.7 0.00029 20.8 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 KFY01405.1 - 0.00015 21.5 3.7 0.00015 21.5 3.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFY01405.1 - 0.0059 16.6 1.6 0.0059 16.6 1.6 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 KFY01405.1 - 0.0081 16.4 3.6 0.0081 16.4 3.6 2.4 2 0 0 2 2 2 1 zinc-ribbon DUF1272 PF06906.11 KFY01405.1 - 0.0092 16.1 7.2 0.49 10.5 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1272) TPR_2 PF07719.17 KFY01405.1 - 0.013 15.5 0.6 0.031 14.4 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 KFY01405.1 - 0.044 13.4 12.7 0.023 14.3 6.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Baculo_RING PF05883.11 KFY01405.1 - 0.17 11.9 1.1 0.61 10.1 0.2 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF3915 PF13054.6 KFY01405.1 - 0.46 10.5 1.8 0.93 9.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) zf-C3HC4_4 PF15227.6 KFY01405.1 - 1.1 9.4 13.8 3.8 7.8 1.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 KFY01405.1 - 1.3 9.3 4.0 1.8 8.8 2.8 1.8 2 0 0 2 2 2 0 Zinc-ribbon like family zf-UDP PF14569.6 KFY01405.1 - 1.4 9.1 4.7 3 8.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 KFY01405.1 - 2.9 7.9 13.8 1.3 9.0 5.8 2.5 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KFY01405.1 - 5.3 7.1 9.3 2.1 8.4 0.8 2.5 2 1 1 3 3 3 0 zinc-ribbons RINGv PF12906.7 KFY01405.1 - 8.6 6.6 15.3 0.69 10.1 8.1 2.3 2 0 0 2 2 2 0 RING-variant domain Fungal_trans PF04082.18 KFY01406.1 - 6.1e-23 81.2 2.5 6.1e-23 81.2 2.5 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01406.1 - 3.4e-08 33.5 8.8 6.2e-08 32.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 KFY01407.1 - 7.8e-11 42.5 0.0 2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY01407.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFY01407.1 - 0.00031 20.8 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFY01407.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KFY01407.1 - 0.00047 20.4 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY01407.1 - 0.015 15.6 0.0 0.061 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KFY01407.1 - 0.02 14.9 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFY01407.1 - 0.059 13.5 0.1 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFY01407.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFY01407.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KFY01407.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Phosphorylase PF00343.20 KFY01409.1 - 0 1052.1 0.0 0 1051.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 KFY01410.1 - 6.5e-109 364.3 0.0 7.5e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFY01410.1 - 9.8e-15 54.4 0.6 8e-10 38.4 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFY01410.1 - 0.00015 21.2 0.4 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFY01410.1 - 0.011 15.9 0.1 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFY01410.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_1 PF00561.20 KFY01411.1 - 7.2e-19 68.4 0.0 8.8e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY01411.1 - 9e-15 55.9 1.1 2.8e-14 54.2 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01411.1 - 6.4e-14 51.8 0.0 2.5e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFY01411.1 - 9.6e-06 25.1 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KFY01411.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KFY01411.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KFY01411.1 - 0.032 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 KFY01411.1 - 0.036 13.9 0.0 1.1 9.1 0.0 2.8 3 1 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KFY01411.1 - 0.04 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 KFY01411.1 - 0.067 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFY01411.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 KFY01411.1 - 0.12 12.1 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Spo7 PF03907.13 KFY01412.1 - 9.2e-96 319.6 0.0 1.6e-95 318.8 0.0 1.4 1 0 0 1 1 1 1 Spo7-like protein GST_C_3 PF14497.6 KFY01413.1 - 1e-13 51.3 0.8 1.6e-13 50.6 0.3 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFY01413.1 - 5.8e-12 45.8 1.2 8.6e-12 45.2 0.1 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFY01413.1 - 7.8e-12 45.4 0.0 1.8e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY01413.1 - 7.4e-11 42.1 0.2 1.2e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY01413.1 - 1.7e-08 34.3 0.0 3.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFY01413.1 - 3.1e-08 33.8 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFY01413.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HET PF06985.11 KFY01424.1 - 5.8e-28 98.1 0.6 1e-27 97.3 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.6 KFY01426.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 KFY01428.1 - 2.1e-05 24.5 11.5 5e-05 23.3 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY01428.1 - 0.0024 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HalX PF08663.10 KFY01428.1 - 0.16 12.3 1.2 0.4 11.0 1.2 1.6 1 0 0 1 1 1 0 HalX domain RasGEF PF00617.19 KFY01431.1 - 0.0095 16.2 0.1 0.089 13.0 0.0 2.5 3 0 0 3 3 3 1 RasGEF domain APH PF01636.23 KFY01432.1 - 0.00088 19.3 0.0 0.0044 17.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family muHD PF10291.9 KFY01442.1 - 1.6e-58 198.2 0.0 2.9e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KFY01442.1 - 4.7e-08 33.2 0.0 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PTRF_SDPR PF15237.6 KFY01442.1 - 0.031 13.9 1.1 0.083 12.5 1.1 1.7 1 0 0 1 1 1 0 PTRF/SDPR family Muted PF14942.6 KFY01442.1 - 0.073 13.4 2.7 0.2 12.0 2.7 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Fis1_TPR_C PF14853.6 KFY01442.1 - 0.096 12.8 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 KFY01443.1 - 8.2e-37 127.0 0.0 1e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01443.1 - 4.8e-18 65.4 0.0 7.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY01443.1 - 0.00069 18.5 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFY01443.1 - 0.0013 18.7 0.1 0.013 15.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tam41_Mmp37 PF09139.11 KFY01444.1 - 4e-126 420.8 0.0 5.8e-126 420.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial RNA_pol_Rpc4 PF05132.14 KFY01444.1 - 0.88 10.0 6.4 6.5 7.2 1.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DAO PF01266.24 KFY01445.1 - 2.1e-59 201.9 2.1 2.4e-59 201.7 2.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY01445.1 - 6e-05 23.2 1.5 0.00013 22.1 1.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFY01445.1 - 0.00033 20.0 0.8 0.58 9.3 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFY01445.1 - 0.00045 19.5 0.4 0.12 11.6 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY01445.1 - 0.028 15.0 0.4 0.32 11.6 0.9 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFY01445.1 - 0.06 12.7 1.1 0.3 10.4 1.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KFY01445.1 - 0.11 12.7 0.2 0.24 11.7 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KFY01445.1 - 0.17 11.9 0.7 0.35 10.8 0.6 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shugoshin_N PF07558.11 KFY01446.1 - 0.13 12.2 1.7 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region CYSTM PF12734.7 KFY01447.1 - 0.25 11.7 80.8 2e+02 2.4 62.1 5.3 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance Peptidase_M43 PF05572.13 KFY01448.1 - 4.1e-16 59.2 0.5 7.1e-16 58.5 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KFY01448.1 - 3.1e-05 24.2 4.9 6.2e-05 23.2 4.7 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFY01448.1 - 3.2e-05 24.5 0.2 6.3e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFY01448.1 - 0.00098 19.0 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFY01448.1 - 0.0047 15.9 2.8 0.0082 15.1 2.7 1.5 1 1 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 KFY01448.1 - 0.0087 15.7 1.3 0.0088 15.7 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFY01448.1 - 0.015 15.2 1.7 0.026 14.4 1.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 KFY01448.1 - 0.061 12.9 3.7 0.11 12.0 3.5 1.7 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 KFY01448.1 - 0.061 12.5 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 Met-zincin FmdA_AmdA PF03069.15 KFY01448.1 - 0.084 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Acetamidase/Formamidase family Peptidase_M54 PF07998.11 KFY01448.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 tRNA-synt_2c PF01411.19 KFY01449.1 - 2.8e-07 29.4 0.0 3.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFY01449.1 - 0.00012 22.1 0.4 0.00026 21.0 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HET PF06985.11 KFY01450.1 - 2.4e-24 86.3 1.9 3.6e-21 76.0 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 KFY01451.1 - 7.6e-50 169.8 0.0 8.6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 KFY01468.1 - 5.1e-26 91.8 0.1 1.3e-25 90.4 0.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KFY01469.1 - 2.2e-05 23.6 0.2 6.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFY01470.1 - 0.028 14.9 11.3 0.06 13.8 0.6 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFY01470.1 - 0.029 14.8 0.8 0.029 14.8 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFY01470.1 - 0.055 14.3 8.7 0.13 13.2 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HhH-GPD PF00730.25 KFY01472.1 - 7.5e-16 58.5 0.0 1.1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFY01472.1 - 4.4e-09 35.8 0.3 1.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KFY01472.1 - 0.038 14.6 0.0 0.13 12.8 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3892 PF13031.6 KFY01472.1 - 0.8 10.4 4.7 12 6.6 3.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) Erf4 PF10256.9 KFY01473.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family 2TM PF13239.6 KFY01474.1 - 0.15 12.4 5.0 0.17 12.2 1.1 2.5 2 0 0 2 2 2 0 2TM domain Ion_trans PF00520.31 KFY01474.1 - 0.3 10.3 5.7 0.25 10.5 3.0 2.0 2 0 0 2 2 2 0 Ion transport protein DUF983 PF06170.12 KFY01474.1 - 5.3 7.5 9.0 1.3 9.4 2.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DUF2070 PF09843.9 KFY01474.1 - 6.3 5.0 13.9 0.082 11.2 6.8 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) ADH_N PF08240.12 KFY01475.1 - 7.9e-25 86.9 1.8 7.9e-25 86.9 1.8 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY01475.1 - 8.7e-20 71.0 0.3 1.8e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KFY01475.1 - 4.2e-06 26.8 13.2 4.2e-06 26.8 13.2 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlaDh_PNT_C PF01262.21 KFY01475.1 - 0.00066 19.0 0.7 0.0015 17.8 0.7 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KFY01475.1 - 0.0015 18.8 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KFY01475.1 - 0.034 14.7 1.5 0.29 11.8 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KFY01475.1 - 0.11 12.9 0.1 0.48 10.9 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFY01475.1 - 0.15 11.4 0.9 0.79 9.1 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Nup_retrotrp_bd PF10599.9 KFY01475.1 - 0.27 11.9 2.8 0.88 10.3 2.8 1.8 1 0 0 1 1 1 0 Retro-transposon transporting motif SGL PF08450.12 KFY01483.1 - 3e-64 217.0 0.1 4.1e-64 216.5 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFY01483.1 - 0.086 13.1 1.3 1.8 9.1 0.0 3.3 4 0 0 4 4 4 0 Two component regulator propeller CAP_GLY PF01302.25 KFY01510.1 - 4.2e-15 55.5 0.3 1e-14 54.3 0.3 1.7 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KFY01510.1 - 1.5e-05 24.8 10.1 0.004 17.0 1.2 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Med4 PF10018.9 KFY01510.1 - 0.0019 17.9 2.2 0.0019 17.9 2.2 3.5 3 1 0 3 3 2 2 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.6 KFY01510.1 - 0.0019 16.9 7.9 0.0019 16.9 7.9 2.9 2 1 0 3 3 3 1 AAA domain DivIC PF04977.15 KFY01510.1 - 0.017 14.8 2.0 0.017 14.8 2.0 4.5 4 1 1 5 5 5 0 Septum formation initiator NPV_P10 PF05531.12 KFY01510.1 - 0.025 15.0 4.0 5.8 7.5 0.4 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glutaredoxin2_C PF04399.13 KFY01510.1 - 0.14 12.0 3.3 7.4 6.4 0.3 2.8 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain zf_PR_Knuckle PF18445.1 KFY01510.1 - 0.16 11.8 1.4 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 PR zinc knuckle motif DUF1664 PF07889.12 KFY01510.1 - 0.17 12.0 14.5 1.5 8.9 3.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KFY01510.1 - 0.62 10.2 18.8 0.74 10.0 3.4 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Pkip-1 PF06878.11 KFY01510.1 - 2.3 8.3 8.4 2.8 8.0 1.1 2.3 1 1 1 2 2 2 0 Pkip-1 protein BLOC1_2 PF10046.9 KFY01510.1 - 4.4 7.7 16.9 1.8 8.9 2.3 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KFY01510.1 - 5.3 7.1 41.4 2.5 8.2 13.4 4.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KFY01510.1 - 5.9 7.3 22.2 1.3 9.4 1.5 4.4 3 2 1 4 4 4 0 Tup N-terminal Fez1 PF06818.15 KFY01510.1 - 7 7.1 42.8 0.33 11.4 13.4 3.3 1 1 2 3 3 3 0 Fez1 CHDCT2 PF08074.11 KFY01510.1 - 9.4 6.4 8.0 6.4 6.9 3.0 2.4 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain Nop14 PF04147.12 KFY01512.1 - 1e-292 973.6 17.2 1.3e-292 973.3 17.2 1.1 1 0 0 1 1 1 1 Nop14-like family Cylicin_N PF15241.6 KFY01512.1 - 2.6 8.2 6.4 0.25 11.5 1.0 2.1 2 0 0 2 2 2 0 Cylicin N-terminus DUF4187 PF13821.6 KFY01513.1 - 7.9e-24 83.2 2.5 2.1e-23 81.9 2.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFY01513.1 - 4.8e-10 39.2 1.4 9.1e-10 38.3 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFY01513.1 - 0.00029 20.9 0.9 0.0011 19.0 0.9 2.1 1 0 0 1 1 1 1 G-patch domain PPR_3 PF13812.6 KFY01514.1 - 2.7e-05 24.2 0.0 0.2 11.8 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain ORC3_N PF07034.11 KFY01515.1 - 9.4e-47 159.7 5.5 2.1e-45 155.3 5.5 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFY01515.1 - 1.5e-28 99.6 0.1 2.4e-16 60.1 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal SLAC1 PF03595.17 KFY01516.1 - 1.1e-58 199.0 42.3 1.3e-58 198.9 42.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4492 PF14899.6 KFY01516.1 - 0.041 13.8 3.5 0.1 12.5 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) NPL4 PF05021.15 KFY01517.1 - 5.6e-138 459.4 0.0 7.8e-138 459.0 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFY01517.1 - 4.1e-68 228.1 0.1 6.2e-68 227.5 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFY01517.1 - 0.00014 22.2 0.0 0.00044 20.7 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KFY01518.1 - 2e-80 268.6 0.1 2.4e-80 268.4 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KFY01518.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Tox-REase-5 PF15648.6 KFY01519.1 - 0.0061 17.0 0.6 0.0081 16.6 0.6 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 tRNA-synt_2d PF01409.20 KFY01520.1 - 3.4e-80 269.1 0.0 5e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KFY01520.1 - 7.7e-17 61.3 0.8 1.8e-16 60.2 0.8 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KFY01520.1 - 1e-05 25.1 0.0 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KFY01520.1 - 0.0004 19.6 0.1 0.0028 16.8 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KFY01520.1 - 0.047 13.7 1.1 0.047 13.7 1.1 3.0 3 0 0 3 3 3 0 PheRS DNA binding domain 2 ESP PF16590.5 KFY01520.1 - 0.15 12.3 0.4 0.61 10.4 0.1 2.1 2 0 0 2 2 2 0 Exocrine gland-secreting peptide CPSase_L_D2 PF02786.17 KFY01521.1 - 7.2e-110 365.5 0.2 1.8e-83 279.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFY01521.1 - 3.3e-41 140.4 0.0 1.1e-40 138.8 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KFY01521.1 - 4.3e-19 68.7 0.1 6.3e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFY01521.1 - 1.2e-18 67.4 1.0 8.4e-09 35.2 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFY01521.1 - 4e-12 46.0 0.0 2.7e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 KFY01521.1 - 4.5e-06 26.4 0.1 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 KFY01521.1 - 4.5e-05 23.3 0.3 0.016 15.0 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KFY01521.1 - 8e-05 22.7 0.2 0.28 11.2 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KFY01521.1 - 0.00055 19.5 0.1 0.16 11.4 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KFY01521.1 - 0.0092 15.6 0.2 0.052 13.1 0.1 2.3 2 0 0 2 2 2 1 ATP-grasp domain KR PF08659.10 KFY01521.1 - 0.056 13.3 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 KR domain MGS PF02142.22 KFY01521.1 - 0.11 12.7 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 MGS-like domain Tax PF02959.16 KFY01521.1 - 0.22 11.0 0.0 0.48 9.9 0.0 1.5 1 0 0 1 1 1 0 HTLV Tax DUF4315 PF14193.6 KFY01522.1 - 0.18 11.9 9.5 0.14 12.1 0.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Sec63 PF02889.16 KFY01523.1 - 3.2e-164 544.3 0.5 7.7e-92 307.1 0.0 2.5 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 KFY01523.1 - 7.2e-47 159.4 0.0 4.3e-27 95.0 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KFY01523.1 - 2.9e-34 117.6 2.4 2.9e-34 117.6 2.4 1.9 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 KFY01523.1 - 5.6e-23 81.8 0.0 6.6e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFY01523.1 - 1.2e-10 41.7 0.0 3.1e-08 33.9 0.0 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFY01523.1 - 1.5e-05 25.3 0.1 0.027 14.8 0.1 3.7 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 KFY01523.1 - 0.097 11.7 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein HTH_19 PF12844.7 KFY01523.1 - 0.26 11.4 1.1 27 4.9 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain PWWP PF00855.17 KFY01524.1 - 1.1e-14 54.6 0.0 1.1e-14 54.6 0.0 4.2 3 2 1 4 4 4 1 PWWP domain Methyltransf_2 PF00891.18 KFY01525.1 - 1.4e-13 50.6 0.0 2.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain UDPGT PF00201.18 KFY01525.1 - 0.00019 20.4 0.1 0.00064 18.6 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFY01525.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_61 PF03443.14 KFY01526.1 - 5.4e-65 219.2 0.2 6.3e-65 219.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BNR_2 PF13088.6 KFY01527.1 - 2.1e-05 24.0 0.0 4.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KFY01527.1 - 0.014 14.2 2.5 0.12 11.2 2.5 2.4 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, Big_3 PF07523.12 KFY01528.1 - 2.6e-10 40.5 0.7 5.2e-10 39.5 0.7 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) RicinB_lectin_2 PF14200.6 KFY01529.1 - 8.5e-35 119.4 7.7 1.8e-15 57.4 0.2 3.5 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like F5_F8_type_C PF00754.25 KFY01529.1 - 1.7e-09 37.8 0.2 1.7e-09 37.8 0.2 2.2 2 0 0 2 2 2 1 F5/8 type C domain Ricin_B_lectin PF00652.22 KFY01529.1 - 1.2e-05 25.6 0.1 2.7e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RTC_insert PF05189.13 KFY01530.1 - 6.6e-31 106.9 0.0 1.4e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KFY01530.1 - 6.2e-27 94.2 0.5 7.7e-27 93.9 0.5 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase MRP_L53 PF10780.9 KFY01531.1 - 2e-21 75.9 1.1 4.1e-21 74.9 1.1 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 KFY01532.1 - 9.8e-14 51.0 2.4 1.3e-13 50.6 0.0 2.4 3 1 0 3 3 3 1 Sec20 Abhydrolase_6 PF12697.7 KFY01533.1 - 2.3e-23 84.0 0.4 3.3e-23 83.4 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01533.1 - 2.6e-08 33.4 0.0 4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY01533.1 - 1.9e-06 27.7 0.0 5.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0261 PF06792.11 KFY01533.1 - 0.0015 17.5 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PGAP1 PF07819.13 KFY01533.1 - 0.054 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KFY01533.1 - 0.1 12.7 0.0 0.87 9.7 0.0 2.0 1 1 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 KFY01533.1 - 0.12 11.9 0.1 5 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KFY01533.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2417 PF10329.9 KFY01534.1 - 6e-88 294.2 0.6 8.4e-88 293.8 0.6 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) TMEM51 PF15345.6 KFY01534.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Rep_fac_C PF08542.11 KFY01535.1 - 5.9e-20 71.5 0.1 1.2e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFY01535.1 - 1.5e-13 51.3 0.0 9.1e-13 48.8 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFY01535.1 - 4.1e-11 42.9 0.0 4.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KFY01535.1 - 1.3e-07 31.8 0.0 5.5e-07 29.7 0.0 2.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KFY01535.1 - 4e-05 23.9 0.1 0.00013 22.3 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KFY01535.1 - 0.00024 21.0 0.0 0.00051 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY01535.1 - 0.00042 20.7 0.0 0.0084 16.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFY01535.1 - 0.00076 19.8 0.1 0.017 15.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFY01535.1 - 0.0008 19.2 0.0 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain HSM3_N PF18795.1 KFY01535.1 - 0.0011 18.4 0.4 0.0016 17.9 0.4 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain AAA_24 PF13479.6 KFY01535.1 - 0.003 17.3 0.0 0.0088 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFY01535.1 - 0.0051 16.2 0.0 0.43 9.9 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KFY01535.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KFY01535.1 - 0.012 15.9 0.1 0.27 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFY01535.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFY01535.1 - 0.045 13.5 0.0 0.24 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFY01535.1 - 0.056 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFY01535.1 - 0.057 13.4 0.1 0.83 9.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFY01535.1 - 0.13 12.8 0.0 0.4 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain F-box PF00646.33 KFY01538.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY01538.1 - 0.0039 17.1 0.1 0.0083 16.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like DZR PF12773.7 KFY01538.1 - 0.014 15.4 1.4 0.16 12.0 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 KFY01542.1 - 5.4e-35 121.0 0.0 6.4e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01542.1 - 2.8e-14 53.0 0.0 4.8e-13 49.0 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFY01542.1 - 0.00056 19.9 0.2 0.0015 18.5 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KFY01543.1 - 8.5e-12 45.5 0.0 0.00033 21.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY01543.1 - 1e-11 44.8 0.0 5.8e-05 23.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY01543.1 - 2.5e-06 27.6 0.3 13 6.4 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KFY01543.1 - 7.2e-05 23.3 0.1 1.7 9.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) SesA PF17107.5 KFY01544.1 - 5.3e-17 62.1 0.5 1.1e-16 61.2 0.1 1.6 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KFY01544.1 - 2e-05 24.1 0.4 3.3e-05 23.3 0.3 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Het-C PF07217.11 KFY01544.1 - 0.078 11.5 0.2 0.091 11.3 0.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AA_permease PF00324.21 KFY01545.1 - 2.5e-140 468.3 38.2 3.1e-140 468.0 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFY01545.1 - 1.7e-34 119.4 40.7 2.2e-34 119.0 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_10 PF13374.6 KFY01545.1 - 0.13 12.2 0.5 0.28 11.1 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_5 PF00266.19 KFY01551.1 - 2.2e-24 86.1 0.0 3.7e-24 85.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KFY01551.1 - 1.6e-19 69.9 0.0 3.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sod_Fe_C PF02777.18 KFY01552.1 - 1.9e-16 60.1 0.0 5.3e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sugar_tr PF00083.24 KFY01558.1 - 6.3e-92 308.8 18.3 8e-92 308.4 18.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01558.1 - 2.8e-12 46.2 40.1 2.7e-11 43.0 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal11_ABD1 PF18535.1 KFY01558.1 - 0.14 12.2 0.4 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) LVIVD PF08309.11 KFY01560.1 - 6.3e-10 38.2 2.6 0.23 10.8 0.0 5.4 5 0 0 5 5 5 4 LVIVD repeat Beta_propel PF09826.9 KFY01560.1 - 0.018 13.9 0.5 0.37 9.6 0.1 2.2 1 1 0 2 2 2 0 Beta propeller domain Abhydrolase_6 PF12697.7 KFY01562.1 - 1.4e-13 52.0 1.2 2.4e-13 51.2 1.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01562.1 - 4.1e-10 39.3 0.1 7.1e-10 38.6 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY01562.1 - 1.7e-05 24.6 0.2 2.5e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFY01562.1 - 0.00073 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFY01563.1 - 9e-37 127.0 0.0 1.2e-25 90.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KFY01563.1 - 6.2e-07 29.1 0.0 5.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 KFY01563.1 - 2.6e-05 24.0 0.0 0.00023 20.9 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KFY01563.1 - 9.3e-05 21.8 0.0 0.002 17.4 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY01563.1 - 0.0012 19.5 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KFY01563.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KFY01563.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFY01563.1 - 0.041 13.5 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KFY01563.1 - 0.11 12.3 0.1 0.67 9.8 0.0 2.0 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal F-box-like PF12937.7 KFY01564.1 - 0.00019 21.3 0.1 0.00085 19.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY01564.1 - 0.034 14.1 0.8 0.21 11.5 0.1 2.4 2 0 0 2 2 2 0 F-box domain gag-asp_proteas PF13975.6 KFY01565.1 - 6.9e-11 42.6 0.0 5.8e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFY01565.1 - 4.7e-07 30.3 0.0 0.0029 18.2 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.10 KFY01565.1 - 2.9e-05 23.9 0.3 0.014 15.2 0.0 3.1 2 1 1 3 3 3 2 Aspartyl protease zf-C2H2 PF00096.26 KFY01565.1 - 0.0036 17.7 13.4 0.038 14.4 1.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY01565.1 - 1.9 9.5 14.4 2.3 9.3 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Rad51 PF08423.11 KFY01572.1 - 5.7e-31 107.7 0.0 8.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFY01572.1 - 8.3e-08 32.0 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFY01572.1 - 2.5e-07 30.3 0.1 1.5e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 KaiC RecA PF00154.21 KFY01572.1 - 7e-07 29.0 0.0 3.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 KFY01572.1 - 0.00085 19.6 0.0 0.0031 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rnf-Nqr PF02508.14 KFY01572.1 - 0.067 13.2 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein ABC_tran PF00005.27 KFY01572.1 - 0.21 12.1 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter FAD_binding_4 PF01565.23 KFY01573.1 - 5e-21 74.9 4.4 1.1e-20 73.8 4.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY01573.1 - 0.0016 18.5 0.4 0.003 17.6 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Jiraiya PF15038.6 KFY01574.1 - 0.26 10.7 4.1 0.57 9.6 4.1 1.5 1 0 0 1 1 1 0 Jiraiya Intg_mem_TP0381 PF09529.10 KFY01574.1 - 2.2 7.7 10.7 31 4.0 0.0 3.0 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) NicO PF03824.16 KFY01574.1 - 3.7 6.8 9.8 6.9 5.9 3.5 2.3 1 1 0 2 2 2 0 High-affinity nickel-transport protein MFS_1 PF07690.16 KFY01575.1 - 1.4e-39 136.0 10.9 1.4e-39 136.0 10.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFY01575.1 - 6.1e-05 22.5 6.7 0.0024 17.2 1.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2970 PF11174.8 KFY01575.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) O-antigen_lig PF13425.6 KFY01575.1 - 0.95 8.2 8.5 0.069 11.9 3.2 1.7 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Phage_holin_2_1 PF04971.12 KFY01575.1 - 3.2 7.8 4.8 27 4.9 0.0 3.2 3 0 0 3 3 3 0 Bacteriophage P21 holin S NicO PF03824.16 KFY01575.1 - 9.5 5.5 9.7 2.8 7.2 2.5 2.6 3 0 0 3 3 3 0 High-affinity nickel-transport protein NUDIX PF00293.28 KFY01576.1 - 3.3e-07 30.4 0.0 6.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KFY01576.1 - 0.00042 20.3 0.0 0.00069 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) Aldo_ket_red PF00248.21 KFY01577.1 - 4.1e-46 157.5 0.1 6.3e-45 153.6 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 KFY01577.1 - 3.2e-20 72.3 0.6 6.1e-20 71.3 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01577.1 - 1.2e-06 28.5 5.7 1.2e-06 28.5 5.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFY01577.1 - 2.2e-05 24.6 9.1 0.01 16.3 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY01577.1 - 0.0017 19.0 7.2 0.66 11.0 0.4 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFY01577.1 - 0.003 17.9 0.9 0.003 17.9 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFY01577.1 - 0.085 13.2 3.7 8.1 6.9 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ADD_DNMT3 PF17980.1 KFY01577.1 - 0.2 11.6 2.8 0.49 10.4 2.8 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 zf-C2H2_6 PF13912.6 KFY01577.1 - 0.89 9.6 4.5 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger MFS_1 PF07690.16 KFY01578.1 - 3.1e-32 111.9 31.1 4.1e-32 111.5 31.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KFY01578.1 - 1.1e-23 84.1 0.0 1.6e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFY01578.1 - 4.3e-06 26.2 0.0 0.0001 21.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY01578.1 - 5.9e-05 22.8 0.1 0.00038 20.1 0.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFY01578.1 - 7.6e-05 21.9 0.1 0.0011 18.1 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFY01578.1 - 0.00018 21.6 0.1 0.00073 19.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY01578.1 - 0.00022 20.6 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY01578.1 - 0.0016 17.2 0.0 0.013 14.3 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFY01578.1 - 0.026 15.1 0.3 0.1 13.1 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFY01578.1 - 0.083 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain MASE2 PF05230.11 KFY01578.1 - 4.7 7.3 9.5 0.66 10.1 2.5 3.0 3 0 0 3 3 3 0 MASE2 domain Zn_clus PF00172.18 KFY01579.1 - 1.8e-06 27.9 9.0 4.2e-06 26.8 9.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY01579.1 - 0.0024 16.7 0.0 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 KFY01580.1 - 1.5e-20 73.7 0.0 4.7e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 KFY01609.1 - 2.8e-10 39.7 0.0 4.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1529 PF07485.11 KFY01609.1 - 0.024 14.5 0.5 0.042 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) Isochorismatase PF00857.20 KFY01618.1 - 2.5e-17 63.6 0.1 3.5e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Voltage_CLC PF00654.20 KFY01620.1 - 3.5e-89 299.5 20.2 3.5e-89 299.5 20.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel WLM PF08325.10 KFY01634.1 - 4.5e-46 157.3 0.0 7.6e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KFY01634.1 - 5.1e-09 35.3 11.4 6.2e-08 31.8 0.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others HutP PF09021.11 KFY01634.1 - 0.017 15.5 0.5 0.028 14.7 0.5 1.3 1 0 0 1 1 1 0 HutP GARS_C PF02843.16 KFY01634.1 - 0.05 13.9 0.2 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DUF45 PF01863.17 KFY01634.1 - 0.2 11.7 0.3 0.34 10.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 CorA PF01544.18 KFY01635.1 - 5.6e-10 39.0 0.0 9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Na_Ca_ex PF01699.24 KFY01635.1 - 0.016 15.2 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF983 PF06170.12 KFY01635.1 - 0.39 11.2 2.5 0.49 10.8 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) TPR_12 PF13424.6 KFY01636.1 - 6.7e-14 51.9 14.2 1.8e-08 34.6 1.8 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY01636.1 - 5.1e-07 29.3 6.9 0.15 12.3 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF2225 PF09986.9 KFY01636.1 - 1.8e-05 24.6 1.8 5.1e-05 23.1 1.8 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) NB-ARC PF00931.22 KFY01636.1 - 0.00012 21.3 0.0 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KFY01636.1 - 0.00031 20.7 6.8 0.46 10.8 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFY01636.1 - 0.0075 16.7 0.0 0.025 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.28 KFY01636.1 - 0.009 15.8 6.1 0.99 9.3 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ATPase PF06745.13 KFY01636.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_16 PF13432.6 KFY01636.1 - 0.13 12.9 2.6 3.2 8.5 0.8 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY01636.1 - 1.1 9.5 4.4 3.3 8.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFY01636.1 - 1.6 9.6 4.1 42 5.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Amidase PF01425.21 KFY01639.1 - 6.6e-29 101.2 0.5 1.2e-28 100.3 0.5 1.4 1 0 0 1 1 1 1 Amidase Actin PF00022.19 KFY01651.1 - 1.6e-140 468.3 0.0 1.8e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFY01651.1 - 0.034 13.0 0.0 6 5.6 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein MBOAT PF03062.19 KFY01652.1 - 1.3e-46 159.6 18.3 2.2e-46 158.9 18.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pam16 PF03656.13 KFY01659.1 - 2.3e-36 124.6 0.7 2.7e-36 124.4 0.7 1.0 1 0 0 1 1 1 1 Pam16 DUF1682 PF07946.14 KFY01659.1 - 0.01 15.1 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5429 PF17494.2 KFY01659.1 - 0.04 13.9 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5429) RCC1 PF00415.18 KFY01660.1 - 4.4e-60 200.1 7.2 5.3e-09 36.6 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFY01660.1 - 2.9e-35 119.4 30.5 7.6e-09 35.1 0.0 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Plasmodium_Vir PF05795.11 KFY01660.1 - 0.12 11.8 3.0 0.19 11.1 3.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HEAT_EZ PF13513.6 KFY01661.1 - 4.6e-33 113.2 13.5 5.5e-17 61.9 0.0 10.5 10 2 2 12 12 11 5 HEAT-like repeat HEAT PF02985.22 KFY01661.1 - 2.6e-26 89.4 9.4 2.9e-06 27.1 0.0 9.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 KFY01661.1 - 1e-18 67.5 0.6 4.5e-06 27.0 0.0 7.6 5 3 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KFY01661.1 - 1.1e-12 48.3 0.0 0.055 13.5 0.0 5.4 5 0 0 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFY01661.1 - 1.8e-07 31.6 0.0 0.84 10.3 0.0 6.1 4 3 4 8 8 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFY01661.1 - 6.2e-07 29.2 0.0 0.21 11.1 0.0 6.7 8 1 1 9 9 9 1 CLASP N terminal MMS19_C PF12460.8 KFY01661.1 - 8.4e-07 28.4 5.1 0.041 13.0 0.0 5.2 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 KFY01661.1 - 1.8e-06 27.8 1.9 4.1e-05 23.4 0.1 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain DRIM PF07539.12 KFY01661.1 - 4.7e-05 21.9 0.0 0.4 8.9 0.0 4.7 3 1 2 5 5 5 1 Down-regulated in metastasis Telomere_reg-2 PF10193.9 KFY01661.1 - 5.2e-05 23.6 0.3 0.0077 16.7 0.0 3.6 4 0 0 4 4 4 1 Telomere length regulation protein Adaptin_N PF01602.20 KFY01661.1 - 6.6e-05 21.7 0.0 1.8 7.0 0.1 4.0 2 2 1 3 3 3 2 Adaptin N terminal region Arm PF00514.23 KFY01661.1 - 7.2e-05 22.7 3.0 0.56 10.3 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KFY01661.1 - 0.0018 18.4 0.1 0.077 13.2 0.0 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KFY01661.1 - 0.1 13.0 0.0 28 5.1 0.0 3.5 3 0 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain RIX1 PF08167.12 KFY01661.1 - 0.18 11.5 0.9 16 5.2 0.0 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 KFY01661.1 - 0.45 11.3 3.6 12 6.9 0.0 5.0 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat PAC4 PF16093.5 KFY01662.1 - 1.1e-19 70.4 0.1 1.6e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 KFY01663.1 - 2.1e-98 328.8 0.0 2.6e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KFY01663.1 - 0.0079 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KFY01664.1 - 3e-43 148.1 2.0 5.9e-43 147.1 1.6 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY01664.1 - 9e-41 139.5 1.5 1e-40 139.3 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFY01664.1 - 2.4e-11 43.9 0.8 4.3e-11 43.0 0.8 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFY01665.1 - 5.7e-05 23.1 0.0 6.6e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFY01665.1 - 0.00058 19.1 0.1 0.055 12.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFY01665.1 - 0.021 14.0 0.0 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFY01665.1 - 0.092 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFY01665.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KFY01675.1 - 5.1e-11 42.4 0.1 6.6e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY01675.1 - 3.8e-07 29.9 0.0 4.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RR_TM4-6 PF06459.12 KFY01679.1 - 0.45 10.3 19.1 0.77 9.5 19.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIIP PF15734.5 KFY01679.1 - 0.58 9.6 7.4 0.87 9.0 7.4 1.2 1 0 0 1 1 1 0 Migration and invasion-inhibitory Red1 PF07964.11 KFY01679.1 - 0.89 7.7 15.9 1.3 7.2 15.9 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DUF966 PF06136.13 KFY01679.1 - 8.5 6.0 13.8 12 5.5 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 KFY01679.1 - 8.8 5.0 14.7 15 4.2 14.7 1.4 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 KFY01679.1 - 8.9 4.8 9.6 13 4.3 9.6 1.2 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 KFY01679.1 - 9.1 6.2 15.9 15 5.5 15.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.16 KFY01680.1 - 4.7 7.2 4.6 6.7 6.7 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mitofilin PF09731.9 KFY01680.1 - 8.3 5.1 30.8 12 4.6 30.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop14 PF04147.12 KFY01692.1 - 1.2e-05 23.8 5.4 1.4e-05 23.6 5.4 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KFY01692.1 - 0.22 9.8 6.4 0.22 9.8 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 KFY01692.1 - 0.37 9.5 3.1 0.38 9.5 3.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 KFY01692.1 - 2.6 7.8 3.0 3.1 7.5 3.0 1.1 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 KFY01692.1 - 4 5.4 10.1 4.5 5.2 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 KFY01693.1 - 3.7 6.0 14.9 4.6 5.7 14.9 1.0 1 0 0 1 1 1 0 Utp14 protein Gtr1_RagA PF04670.12 KFY01694.1 - 1.3e-91 306.1 0.0 2.1e-91 305.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1275 PF06912.11 KFY01694.1 - 4.2e-29 101.8 8.5 4.2e-29 101.8 8.5 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1275) 60KD_IMP PF02096.20 KFY01694.1 - 2.2e-16 60.2 0.3 4.4e-16 59.2 0.3 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Roc PF08477.13 KFY01694.1 - 2.3e-07 31.1 0.0 5.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFY01694.1 - 2.6e-06 27.5 0.0 8.9e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFY01694.1 - 4.5e-06 26.2 0.0 8.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFY01694.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFY01694.1 - 0.00095 19.1 0.1 0.69 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFY01694.1 - 0.022 13.9 2.2 2.1 7.4 0.8 2.3 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 KFY01694.1 - 0.029 14.1 0.4 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 KFY01694.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFY01694.1 - 0.046 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PEP_mutase PF13714.6 KFY01695.1 - 2e-41 142.0 0.2 2.5e-41 141.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFY01695.1 - 9e-23 80.5 0.2 1.4e-22 79.9 0.2 1.3 1 0 0 1 1 1 1 Isocitrate lyase family TGT PF01702.18 KFY01696.1 - 1.2e-60 205.5 0.0 1.5e-60 205.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.19 KFY01697.1 - 1.6e-21 76.2 0.2 2.6e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Wzy_C PF04932.15 KFY01697.1 - 5.4 6.6 8.0 0.26 10.9 0.1 2.7 2 1 0 2 2 2 0 O-Antigen ligase Ank_3 PF13606.6 KFY01713.1 - 6.1e-26 87.6 0.2 0.0004 20.6 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.7 KFY01713.1 - 9.6e-26 90.2 0.0 2.8e-14 53.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY01713.1 - 4.4e-23 81.4 0.0 4.7e-08 33.4 0.0 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY01713.1 - 1.8e-22 79.1 0.7 9e-09 35.4 0.0 6.7 3 1 4 7 7 7 5 Ankyrin repeats (many copies) HET PF06985.11 KFY01713.1 - 7e-22 78.3 0.1 2.4e-21 76.6 0.1 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.30 KFY01713.1 - 2e-14 53.3 0.1 0.0027 18.1 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ferlin_C PF16165.5 KFY01714.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Metallophos PF00149.28 KFY01715.1 - 5.4e-12 46.6 0.2 7.5e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.18 KFY01716.1 - 0.00034 20.7 7.5 0.00065 19.8 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosidase_ig PF17786.1 KFY01717.1 - 1.6e-10 41.5 0.0 4.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFY01717.1 - 3.3e-10 40.6 0.0 6.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFY01717.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 KFY01718.1 - 9.9e-76 255.4 18.3 1.1e-75 255.2 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01718.1 - 1.2e-35 123.1 40.3 4.6e-28 98.2 23.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_130 PF04041.13 KFY01719.1 - 4.6e-44 150.7 0.0 5.5e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KFY01719.1 - 1.7e-08 34.1 0.3 1.6e-05 24.4 0.2 3.7 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFY01719.1 - 2.4e-08 33.9 0.5 8.7e-06 25.5 0.0 2.8 2 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_130 PF04041.13 KFY01720.1 - 7.2e-46 156.6 0.0 1e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 KFY01720.1 - 1.6e-10 41.1 1.5 2.1e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KFY01720.1 - 2.9e-10 39.9 1.7 0.00016 21.1 0.0 3.9 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Zn_clus PF00172.18 KFY01721.1 - 5.3e-07 29.7 12.0 9.4e-07 28.9 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KFY01722.1 - 1.4e-33 116.4 0.1 3.4e-33 115.1 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY01722.1 - 3.1e-10 40.3 0.0 4.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KFY01722.1 - 0.0003 21.0 0.1 0.00051 20.3 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KFY01722.1 - 0.038 13.0 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ydhR PF08803.11 KFY01722.1 - 0.08 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR GFA PF04828.14 KFY01723.1 - 2.1e-21 76.0 0.0 2.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFY01723.1 - 0.031 13.9 0.4 0.031 13.9 0.4 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 KFY01723.1 - 0.061 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Isochorismatase PF00857.20 KFY01724.1 - 3.8e-40 137.9 0.0 4.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.11 KFY01724.1 - 0.036 14.1 0.0 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Ribonuclease_T2 PF00445.18 KFY01724.1 - 0.17 12.1 1.9 0.32 11.2 0.7 1.8 2 0 0 2 2 2 0 Ribonuclease T2 family DUF3533 PF12051.8 KFY01725.1 - 2.5e-91 306.4 11.3 3.1e-91 306.1 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ECH_1 PF00378.20 KFY01726.1 - 2.3e-25 89.4 0.0 2.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY01726.1 - 1e-09 38.4 0.0 1.3e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyco_hydro_20 PF00728.22 KFY01727.1 - 4.3e-74 250.0 0.0 6e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFY01727.1 - 1.1e-13 52.0 0.0 3.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFY01727.1 - 0.00018 22.3 0.0 0.00031 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Aminotran_3 PF00202.21 KFY01739.1 - 9.7e-111 370.3 0.0 1.3e-110 369.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_ab PF00006.25 KFY01740.1 - 3e-66 223.1 0.0 4.6e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HMGL-like PF00682.19 KFY01740.1 - 3.7e-46 157.8 0.0 5.2e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ATP-synt_ab_N PF02874.23 KFY01740.1 - 3.3e-13 50.0 0.9 3.3e-13 50.0 0.9 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KFY01740.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) HLH PF00010.26 KFY01748.1 - 1.8e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 KFY01748.1 - 0.0069 15.8 0.5 0.0087 15.4 0.5 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family ADH_N_2 PF16884.5 KFY01749.1 - 3e-22 78.6 0.0 5.4e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFY01749.1 - 5.9e-18 65.1 0.0 9.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01749.1 - 1e-05 26.6 0.0 1.9e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KFY01749.1 - 0.048 13.4 0.1 0.61 9.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2855) tRNA-synt_2b PF00587.25 KFY01750.1 - 8.2e-32 110.6 0.0 8.8e-28 97.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFY01750.1 - 0.00034 20.7 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain Helo_like_N PF17111.5 KFY01751.1 - 0.5 9.7 1.9 4.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins adh_short_C2 PF13561.6 KFY01752.1 - 4.2e-51 173.7 0.2 5.7e-51 173.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY01752.1 - 2.9e-44 150.9 1.2 4.2e-44 150.3 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY01752.1 - 6e-09 36.1 1.7 8.3e-09 35.6 1.7 1.1 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.6 KFY01753.1 - 1.2e-40 139.4 0.0 2.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFY01753.1 - 1.5e-09 38.1 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 KFY01754.1 - 7.3e-24 84.2 0.0 7.3e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01754.1 - 1e-07 31.9 13.7 1.9e-07 31.1 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KFY01777.1 - 4.9e-06 26.6 8.5 9.4e-06 25.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.10 KFY01778.1 - 1.3e-73 247.9 8.4 2.3e-73 247.1 2.8 2.7 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KFY01778.1 - 8.1e-08 32.7 0.0 3.1e-05 24.4 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY01778.1 - 0.00037 20.7 3.8 0.099 12.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat MerR_2 PF13591.6 KFY01778.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein TPR_2 PF07719.17 KFY01778.1 - 0.96 9.7 12.2 1.2 9.4 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY01778.1 - 2.2 8.7 7.7 24 5.4 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_4 PF13637.6 KFY01779.1 - 9.6e-32 109.0 1.7 1.9e-09 37.8 0.0 7.5 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY01779.1 - 4.5e-25 88.1 0.0 5.6e-08 33.3 0.1 5.2 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY01779.1 - 8.5e-25 86.5 1.1 1.1e-06 28.8 0.3 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01779.1 - 3.3e-21 73.1 1.8 9.9e-05 22.5 0.0 7.6 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KFY01779.1 - 3.3e-20 71.5 7.6 0.00078 19.8 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat CtaG_Cox11 PF04442.14 KFY01780.1 - 6.1e-60 201.6 0.0 1.1e-59 200.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 C2 PF00168.30 KFY01780.1 - 1.8e-29 102.0 0.0 1.6e-18 66.9 0.0 2.8 2 0 0 2 2 2 2 C2 domain Sec6 PF06046.13 KFY01781.1 - 3.5e-168 560.6 4.5 5.1e-168 560.0 4.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 CREPT PF16566.5 KFY01781.1 - 0.11 12.7 4.8 4.6 7.4 0.1 3.3 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Vps53_N PF04100.12 KFY01781.1 - 0.36 9.7 9.3 0.13 11.2 2.3 2.5 1 1 0 2 2 2 0 Vps53-like, N-terminal YgaB PF14182.6 KFY01781.1 - 0.9 10.0 4.8 0.46 10.9 0.8 2.6 2 0 0 2 2 2 0 YgaB-like protein Ribosomal_L30 PF00327.20 KFY01782.1 - 3.6e-13 49.2 0.5 5.9e-13 48.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NUC173 PF08161.12 KFY01783.1 - 4.4e-80 268.1 1.9 2.2e-76 256.1 0.0 3.5 4 0 0 4 4 4 2 NUC173 domain HEAT_2 PF13646.6 KFY01783.1 - 0.036 14.4 2.3 0.71 10.3 0.1 4.1 3 1 1 4 4 4 0 HEAT repeats TFCD_C PF12612.8 KFY01783.1 - 0.046 13.6 7.4 1.8 8.4 0.0 5.0 4 2 1 5 5 5 0 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 KFY01783.1 - 0.18 12.4 2.0 6.4 7.5 0.1 3.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region XRN_M PF17846.1 KFY01783.1 - 3.2 6.6 6.1 0.5 9.3 0.1 2.2 2 0 0 2 2 2 0 Xrn1 helical domain ORC5_C PF14630.6 KFY01783.1 - 4.3 6.8 6.1 0.58 9.6 0.9 2.2 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Iron_permease PF04120.12 KFY01820.1 - 0.82 9.4 10.4 1.9 8.3 10.4 1.5 1 0 0 1 1 1 0 Low affinity iron permease Aa_trans PF01490.18 KFY01822.1 - 3.6e-52 177.5 39.2 4.4e-52 177.2 39.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.10 KFY01822.1 - 0.23 11.3 0.6 0.4 10.5 0.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Dynactin PF12455.8 KFY01823.1 - 6.2e-111 370.2 8.6 6.2e-111 370.2 8.6 3.3 2 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 KFY01823.1 - 6.2e-23 80.6 0.3 1.1e-22 79.8 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain F_actin_bind PF08919.10 KFY01823.1 - 0.42 10.7 4.8 4.6 7.4 0.3 4.0 3 0 0 3 3 3 0 F-actin binding DUF2443 PF10398.9 KFY01823.1 - 3.7 7.7 7.0 12 6.1 0.2 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2443) NPV_P10 PF05531.12 KFY01823.1 - 7.1 7.2 25.2 28 5.3 0.2 6.9 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein CLN3 PF02487.17 KFY01824.1 - 1.2e-162 541.6 4.5 1.4e-162 541.4 4.5 1.0 1 0 0 1 1 1 1 CLN3 protein Rxt3 PF08642.10 KFY01825.1 - 2e-42 145.0 1.1 5e-42 143.7 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KFY01825.1 - 4.2e-05 23.6 0.0 0.00086 19.4 0.0 2.3 2 0 0 2 2 2 1 LCCL domain HET PF06985.11 KFY01826.1 - 4.2e-12 46.7 8.0 1.5e-09 38.4 0.6 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ribonuclease_T2 PF00445.18 KFY01827.1 - 9e-42 143.4 0.2 1.6e-41 142.5 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family Pec_lyase_C PF00544.19 KFY01828.1 - 8.6e-37 126.8 10.5 1.2e-36 126.3 10.5 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFY01828.1 - 0.0019 18.1 13.9 0.035 13.9 14.0 2.4 1 1 0 1 1 1 1 Right handed beta helix region FAD_binding_4 PF01565.23 KFY01829.1 - 8.2e-20 71.0 3.4 2.3e-19 69.5 3.4 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY01829.1 - 0.001 19.1 0.1 0.0024 17.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 KFY01830.1 - 1.7e-71 240.8 0.0 7.2e-71 238.7 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFY01830.1 - 2.1e-50 171.7 0.3 1.7e-49 168.7 0.0 2.6 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFY01830.1 - 4.7e-43 147.9 0.0 9.3e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY01830.1 - 1.7e-33 115.1 0.8 5.1e-33 113.6 0.8 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KFY01830.1 - 5.4e-09 36.3 1.3 1.4e-08 35.0 1.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KFY01830.1 - 6.7e-09 35.4 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFY01830.1 - 7.2e-09 36.1 0.1 6.8e-08 33.0 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFY01830.1 - 1.7e-06 27.6 0.1 4.3e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.27 KFY01831.1 - 1.6e-16 60.9 2.0 1.8e-15 57.5 1.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFY01831.1 - 7e-05 22.4 0.1 0.00015 21.3 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KFY01831.1 - 0.0015 18.5 0.1 0.0059 16.6 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 KFY01831.1 - 0.044 13.7 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AflR PF08493.10 KFY01833.1 - 8.8e-18 64.8 5.7 1.8e-17 63.8 5.7 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KFY01833.1 - 5.5e-06 26.4 12.5 1e-05 25.6 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.8 KFY01834.1 - 4.5e-18 65.4 0.1 1.3e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) adh_short PF00106.25 KFY01835.1 - 2.6e-23 82.5 0.0 1e-20 74.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY01835.1 - 1.3e-13 51.1 0.0 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY01835.1 - 1.6e-09 38.0 0.0 2.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFY01835.1 - 0.00034 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFY01835.1 - 0.0053 16.2 0.1 0.0088 15.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ald_Xan_dh_C2 PF02738.18 KFY01836.1 - 4.2e-206 685.7 2.4 6e-206 685.2 2.4 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFY01836.1 - 3.5e-46 157.1 0.0 7.6e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KFY01836.1 - 1.2e-33 115.3 0.1 4.2e-33 113.6 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KFY01836.1 - 2e-29 102.2 0.0 5.8e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KFY01836.1 - 5.3e-29 100.1 0.1 1.2e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFY01836.1 - 3.8e-08 33.2 0.2 2.1e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fic PF02661.18 KFY01837.1 - 4.2e-14 53.2 0.0 2e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 Fic/DOC family DUF2382 PF09557.10 KFY01837.1 - 0.027 14.7 0.2 0.089 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) 6PF2K PF01591.18 KFY01856.1 - 2.7e-82 275.4 0.1 3.4e-82 275.1 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFY01856.1 - 3.3e-33 115.0 0.0 6.2e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KFY01856.1 - 2.8e-05 23.7 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFY01856.1 - 6.9e-05 23.0 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Atracotoxin PF05353.11 KFY01856.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Delta Atracotoxin WSC PF01822.19 KFY01857.1 - 1.9e-68 226.7 67.5 5.3e-19 68.2 10.4 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KFY01857.1 - 1.4e-30 106.3 0.0 1e-29 103.5 0.0 2.2 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KFY01857.1 - 7.4e-24 83.9 0.6 1.1e-22 80.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) DUF5576 PF17739.1 KFY01857.1 - 0.074 13.2 0.3 0.22 11.6 0.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5576) Kelch_2 PF07646.15 KFY01857.1 - 0.34 11.0 1.9 2.5 8.2 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.6 KFY01857.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 Kelch motif PS_Dcarbxylase PF02666.15 KFY01859.1 - 6.2e-47 159.7 0.0 7.2e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTPLA PF04387.14 KFY01860.1 - 4.4e-47 159.9 5.2 5.9e-47 159.4 5.2 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA GMC_oxred_N PF00732.19 KFY01862.1 - 1.3e-50 172.5 0.2 2e-50 171.9 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Ank_2 PF12796.7 KFY01862.1 - 7e-50 167.6 11.7 4.7e-15 55.9 0.1 7.0 3 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY01862.1 - 8.3e-39 131.5 14.3 2.4e-11 43.9 0.1 9.9 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY01862.1 - 7.7e-30 102.6 10.1 1.7e-09 37.7 0.2 10.8 9 2 2 11 11 11 6 Ankyrin repeats (many copies) HATPase_c PF02518.26 KFY01862.1 - 5.2e-26 91.3 0.0 1.2e-25 90.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank PF00023.30 KFY01862.1 - 2.2e-23 81.6 26.1 3.7e-06 27.1 0.2 12.9 11 2 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 KFY01862.1 - 7e-23 78.2 15.0 0.0018 18.6 0.0 13.6 13 1 1 14 14 13 4 Ankyrin repeat HisKA PF00512.25 KFY01862.1 - 2.2e-16 59.6 0.2 4.7e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KFY01862.1 - 1.7e-15 57.1 0.3 4.1e-15 55.9 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 KFY01862.1 - 2.7e-14 53.3 0.0 3.3e-10 40.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KFY01862.1 - 5e-13 49.0 0.0 5.8e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KFY01862.1 - 4.7e-11 42.9 0.0 0.00071 19.8 0.0 3.1 3 0 0 3 3 3 2 PAS fold FAD_binding_2 PF00890.24 KFY01862.1 - 9.3e-06 25.0 3.7 0.00034 19.8 0.5 3.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY01862.1 - 0.00018 20.9 0.4 0.00068 19.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY01862.1 - 0.0013 18.4 1.5 0.24 11.0 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY01862.1 - 0.0029 16.9 0.1 0.005 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY01862.1 - 0.0049 17.1 0.9 0.017 15.3 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 KFY01864.1 - 1.6e-14 53.6 0.6 2.9e-14 52.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 KFY01865.1 - 1.3e-57 195.0 0.0 1.7e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 KFY01866.1 - 1.3e-32 113.1 26.5 1.3e-32 113.1 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 KFY01867.1 - 2e-70 237.7 0.2 3.5e-70 236.8 0.2 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KFY01867.1 - 4.5e-08 32.4 16.3 1.2e-07 31.0 16.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY01867.1 - 0.4 9.5 18.2 3.8 6.3 2.4 3.3 2 2 0 2 2 2 0 Sugar (and other) transporter Methyltransf_2 PF00891.18 KFY01868.1 - 1.6e-18 66.8 0.0 3.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFY01868.1 - 0.00022 21.1 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 KFY01868.1 - 0.0075 16.3 1.2 0.021 14.8 0.1 2.3 2 0 0 2 2 2 1 Dimerisation domain HTH_IclR PF09339.10 KFY01868.1 - 0.04 13.7 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain GPI-anchored PF10342.9 KFY01869.1 - 8.4e-11 42.5 1.4 9.5e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 KFY01869.1 - 1.1e-05 24.8 0.2 1.1e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 KFY01869.1 - 0.00035 20.6 0.0 0.00078 19.5 0.0 1.5 2 0 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Patatin PF01734.22 KFY01870.1 - 4.5e-15 56.4 0.0 7.6e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3337 PF11816.8 KFY01873.1 - 3.8e-52 176.6 0.0 6.9e-52 175.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) DDHD PF02862.17 KFY01873.1 - 7.6e-26 91.6 4.0 1.2e-16 61.6 0.0 3.3 3 1 0 4 4 4 2 DDHD domain WD40 PF00400.32 KFY01873.1 - 7.2e-19 67.8 9.9 0.00079 20.2 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY01873.1 - 0.0047 17.2 0.1 0.022 15.1 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY01873.1 - 0.0076 14.9 0.5 0.083 11.5 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFY01873.1 - 0.25 10.3 0.1 1.5 7.7 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_3 PF01494.19 KFY01875.1 - 7.3e-74 249.1 0.0 9.6e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFY01875.1 - 8.4e-40 136.5 0.0 1.3e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KFY01875.1 - 0.00046 19.5 0.0 0.0093 15.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY01875.1 - 0.0087 16.6 0.0 0.073 13.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01875.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY01875.1 - 0.024 14.2 0.1 0.31 10.6 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFY01875.1 - 0.028 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFY01875.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFY01875.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 KFY01875.1 - 0.095 13.2 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Peptidase_C48 PF02902.19 KFY01876.1 - 9.7e-26 90.9 0.0 2.1e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DSPc PF00782.20 KFY01877.1 - 1.5e-27 96.1 0.0 1.1e-18 67.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFY01877.1 - 0.0017 17.9 0.1 0.0085 15.7 0.1 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Endonuclease_NS PF01223.23 KFY01894.1 - 2.7e-55 187.7 0.0 3.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ferric_reduct PF01794.19 KFY01900.1 - 6.2e-05 23.1 2.1 6.2e-05 23.1 2.1 1.8 1 1 1 2 2 2 2 Ferric reductase like transmembrane component YxiJ PF14176.6 KFY01901.1 - 0.055 13.9 0.9 15 6.1 0.1 3.4 2 1 1 3 3 3 0 YxiJ-like protein DUF3723 PF12520.8 KFY01904.1 - 2.7e-118 395.9 0.0 1.2e-107 360.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.25 KFY01905.1 - 6.1e-09 35.6 0.0 5.4e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01905.1 - 4.2e-08 32.8 0.0 1.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase IMS_HHH PF11798.8 KFY01905.1 - 0.16 12.4 0.0 0.56 10.7 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif mRNA_cap_enzyme PF01331.19 KFY01926.1 - 4e-48 163.8 0.0 5.8e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFY01926.1 - 1.6e-36 125.3 0.3 2.3e-36 124.7 0.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KFY01926.1 - 3.1e-05 23.7 0.0 0.02 14.5 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain uDENN PF03456.18 KFY01926.1 - 0.0085 16.8 0.1 0.17 12.7 0.0 2.7 2 1 0 2 2 2 1 uDENN domain HEAT PF02985.22 KFY01928.1 - 4.7e-09 35.7 1.7 0.12 12.7 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 KFY01928.1 - 2.7e-05 24.5 1.5 0.0063 16.9 0.1 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KFY01928.1 - 0.87 10.2 3.1 11 6.6 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat WAC_Acf1_DNA_bd PF10537.9 KFY01944.1 - 1.8e-38 131.1 2.0 2.3e-38 130.8 0.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KFY01944.1 - 2.2e-17 63.3 3.3 1.1e-16 61.2 0.0 3.1 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KFY01944.1 - 2.4e-17 63.0 1.3 4.3e-17 62.2 1.3 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KFY01944.1 - 2e-08 33.5 0.0 7.4e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 GCN5L1 PF06320.13 KFY01944.1 - 0.036 14.2 1.7 0.19 11.9 1.7 2.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) AD PF09793.9 KFY01944.1 - 0.54 10.4 2.6 2.4 8.4 2.6 2.1 1 0 0 1 1 1 0 Anticodon-binding domain Holin_BhlA PF10960.8 KFY01944.1 - 3.2 7.8 4.6 7.9 6.5 3.7 2.1 2 0 0 2 2 2 0 BhlA holin family Ribosomal_L30_N PF08079.12 KFY01949.1 - 1.3e-26 92.7 18.5 1.3e-26 92.7 18.5 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFY01949.1 - 3.2e-18 65.3 2.5 7.6e-18 64.2 2.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e PIR PF00399.19 KFY01964.1 - 4.1 7.1 11.2 2.1 8.0 2.4 2.6 2 0 0 2 2 2 0 Yeast PIR protein repeat Mito_carr PF00153.27 KFY01965.1 - 1.5e-53 178.7 1.4 2.1e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr5 PF14420.6 KFY01966.1 - 2e-18 66.3 3.8 3.7e-18 65.5 3.8 1.4 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_3_C PF01915.22 KFY01967.1 - 2.7e-41 141.8 0.0 4.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY01967.1 - 1.4e-34 120.0 0.0 2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFY01967.1 - 6.9e-08 32.5 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TraE PF05309.11 KFY01968.1 - 0.0097 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 TraE protein FAD_binding_4 PF01565.23 KFY01969.1 - 5.2e-22 78.1 4.2 9.9e-22 77.2 4.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY01969.1 - 0.00011 22.3 0.1 0.00023 21.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KFY01970.1 - 1.6e-29 102.9 19.8 1.6e-29 102.9 19.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFY01970.1 - 0.02 13.8 0.3 0.02 13.8 0.3 2.2 2 0 0 2 2 2 0 MFS_1 like family TauD PF02668.16 KFY01971.1 - 3e-61 207.6 0.2 3.6e-61 207.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.8 KFY01972.1 - 6.6e-53 179.9 0.1 1.2e-52 179.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01972.1 - 2.5e-07 30.7 21.4 5.7e-05 23.1 8.8 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFY01972.1 - 4.8e-07 29.9 12.0 0.0058 17.0 4.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFY01972.1 - 0.00037 20.8 3.0 0.00037 20.8 3.0 4.3 4 1 0 4 4 4 1 Zinc-finger double domain BolA PF01722.18 KFY01972.1 - 0.0077 16.5 0.7 0.29 11.4 0.4 2.5 1 1 1 2 2 2 1 BolA-like protein zf-C2H2_4 PF13894.6 KFY01972.1 - 0.014 16.2 9.8 0.033 15.0 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFY01972.1 - 0.022 14.8 1.0 0.022 14.8 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFY01972.1 - 0.027 14.8 3.1 6.6 7.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY01972.1 - 0.076 13.4 3.9 5.4 7.5 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_hydro_3_C PF01915.22 KFY01973.1 - 3e-42 144.9 0.0 4.4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY01973.1 - 1.9e-38 132.6 0.0 2.7e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 KFY01973.1 - 1.6e-15 57.1 9.0 3.5e-15 55.9 9.0 1.6 1 0 0 1 1 1 1 WSC domain Toxin_3 PF00537.18 KFY01973.1 - 2.1 8.6 5.3 0.25 11.6 0.4 2.0 2 0 0 2 2 2 0 Scorpion toxin-like domain Amidohydro_1 PF01979.20 KFY01974.1 - 1.4e-72 244.9 0.1 1.7e-72 244.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFY01974.1 - 8.5e-20 71.7 0.2 1.7e-15 57.5 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KFY01974.1 - 0.00068 19.1 0.0 0.0019 17.6 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 KFY01975.1 - 8.1e-61 205.8 31.1 1.4e-58 198.5 31.1 3.0 1 1 0 1 1 1 1 Permease family DUF716 PF04819.12 KFY01975.1 - 0.07 12.8 3.1 1 9.0 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF716) ABC2_membrane PF01061.24 KFY01976.1 - 8.3e-30 103.8 29.2 1.2e-29 103.3 29.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFY01976.1 - 1.7e-25 90.2 0.0 2.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFY01976.1 - 3.2e-06 27.2 0.4 2.7e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFY01976.1 - 1.5e-05 24.7 0.1 3.1e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY01976.1 - 8.7e-05 23.0 0.1 0.00015 22.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFY01976.1 - 0.00084 19.2 0.0 0.47 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFY01976.1 - 0.002 18.1 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFY01976.1 - 0.0065 16.7 0.1 0.017 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFY01976.1 - 0.0092 15.7 0.1 0.023 14.4 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 KFY01976.1 - 0.012 16.0 0.1 0.053 14.0 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KFY01976.1 - 0.017 14.6 0.0 0.091 12.2 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFY01976.1 - 0.017 14.9 0.2 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFY01976.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KFY01976.1 - 0.036 14.3 0.2 0.066 13.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFY01976.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KFY01976.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFY01976.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KFY01976.1 - 0.097 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KFY01976.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KFY01976.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFY01976.1 - 0.2 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFY01976.1 - 0.23 12.0 0.1 0.5 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KFY01976.1 - 0.41 9.2 0.4 0.87 8.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KFY01977.1 - 5.1e-05 22.4 0.0 7.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01977.1 - 0.005 16.9 1.4 0.0091 16.1 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFY01978.1 - 3.6e-27 95.1 0.0 4.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY01978.1 - 1.3e-12 47.8 0.0 2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFY01978.1 - 2.1e-06 27.4 0.2 2.4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFY01978.1 - 0.071 13.0 0.1 0.18 11.7 0.1 1.8 1 1 0 1 1 1 0 KR domain GST_N_2 PF13409.6 KFY01979.1 - 6.8e-08 32.7 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFY01979.1 - 2.1e-06 28.0 0.0 5.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFY01979.1 - 0.0001 22.5 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY01979.1 - 0.0062 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KFY01980.1 - 1.1e-78 265.0 0.0 1.3e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFY01982.1 - 1.2e-18 67.2 63.3 9.1e-16 57.7 35.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFY01982.1 - 0.0001 21.8 13.5 0.00016 21.1 13.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB AgrD PF05931.11 KFY01982.1 - 0.037 14.1 0.2 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Staphylococcal AgrD protein Zip PF02535.22 KFY01998.1 - 4.3e-05 22.9 0.0 4.5e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UPF0060 PF02694.15 KFY02003.1 - 0.00042 20.5 1.7 0.00068 19.8 1.7 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family TcpE PF12648.7 KFY02003.1 - 0.15 12.6 2.2 0.27 11.8 2.2 1.4 1 0 0 1 1 1 0 TcpE family Arteri_Gl PF00951.18 KFY02003.1 - 0.74 9.6 6.0 1.1 9.1 6.0 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF5014 PF16406.5 KFY02004.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5014) Pkinase PF00069.25 KFY02005.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain GP11 PF08677.10 KFY02005.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein Filament PF00038.21 KFY02007.1 - 0.00034 20.3 7.3 0.0064 16.1 0.7 3.0 3 0 0 3 3 3 1 Intermediate filament protein CLZ PF16526.5 KFY02007.1 - 0.0024 18.2 1.8 0.31 11.4 0.0 4.2 4 1 1 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 KFY02007.1 - 0.0026 17.7 1.3 2.9 7.8 0.0 3.0 3 1 0 3 3 3 2 Sec34-like family Sporozoite_P67 PF05642.11 KFY02007.1 - 0.0058 14.8 0.0 0.012 13.8 0.0 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen ZapB PF06005.12 KFY02007.1 - 0.0066 16.9 5.0 6.3 7.3 0.3 3.6 3 0 0 3 3 3 0 Cell division protein ZapB DUF4515 PF14988.6 KFY02007.1 - 0.016 15.1 0.4 0.016 15.1 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) PKcGMP_CC PF16808.5 KFY02007.1 - 0.022 14.6 0.6 0.022 14.6 0.6 3.1 4 0 0 4 4 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 KFY02007.1 - 0.024 14.9 0.5 13 6.1 0.0 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family WXG100 PF06013.12 KFY02007.1 - 0.028 14.7 0.0 1e+02 3.2 0.0 4.2 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 KFY02007.1 - 0.029 14.4 2.0 4 7.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KFY02007.1 - 0.044 14.1 0.2 0.044 14.1 0.2 2.9 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Tup_N PF08581.10 KFY02007.1 - 0.053 13.8 0.5 2 8.8 0.0 3.0 2 1 0 2 2 2 0 Tup N-terminal TMF_TATA_bd PF12325.8 KFY02007.1 - 0.066 13.4 13.1 0.1 12.8 0.7 4.1 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF148 PF02520.17 KFY02007.1 - 0.077 13.1 0.1 30 4.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function DUF148 SHE3 PF17078.5 KFY02007.1 - 0.089 12.5 3.7 2.4 7.8 0.0 3.0 2 2 0 2 2 2 0 SWI5-dependent HO expression protein 3 ApoO PF09769.9 KFY02007.1 - 0.094 12.7 0.3 1 9.3 0.0 2.8 3 1 0 3 3 3 0 Apolipoprotein O Retrotran_gag_2 PF14223.6 KFY02007.1 - 0.12 12.0 0.2 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Fzo_mitofusin PF04799.13 KFY02007.1 - 0.13 11.8 2.2 2.1 7.8 0.1 3.0 3 0 0 3 3 3 0 fzo-like conserved region Cortex-I_coil PF09304.10 KFY02007.1 - 0.2 11.9 3.6 12 6.1 0.0 3.1 3 0 0 3 3 3 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.22 KFY02007.1 - 0.34 11.2 3.9 12 6.2 0.1 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KFY02007.1 - 0.35 12.0 0.1 0.35 12.0 0.1 2.8 3 1 0 3 3 2 0 Protein SOGA SNARE PF05739.19 KFY02007.1 - 0.43 10.6 1.5 14 5.7 0.0 2.6 2 0 0 2 2 2 0 SNARE domain FlaC_arch PF05377.11 KFY02007.1 - 0.63 10.5 2.6 14 6.2 0.0 3.9 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) PhoU PF01895.19 KFY02007.1 - 0.8 10.2 3.1 4.4 7.8 0.1 3.0 3 0 0 3 3 3 0 PhoU domain DUF5082 PF16888.5 KFY02007.1 - 0.84 9.9 6.8 3.8 7.8 0.4 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 KFY02007.1 - 1.3 8.5 9.9 0.12 11.8 1.4 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 5 Csm1_N PF18504.1 KFY02007.1 - 2 8.8 5.0 10 6.5 0.6 3.9 3 2 2 5 5 5 0 Csm1 N-terminal domain APG6_N PF17675.1 KFY02007.1 - 2.3 8.8 11.5 0.23 12.0 0.5 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 KFY02007.1 - 4.4 6.9 12.2 0.066 12.9 1.2 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease WD40 PF00400.32 KFY02009.1 - 4.4e-107 347.0 41.7 2.4e-10 40.8 0.3 11.2 11 0 0 11 11 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY02009.1 - 6.5e-31 106.5 27.5 0.00086 19.6 0.1 10.5 3 1 9 12 12 11 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY02009.1 - 1.7e-19 69.9 40.5 0.043 12.5 0.5 10.2 1 1 9 10 10 10 10 Nucleoporin Nup120/160 NACHT PF05729.12 KFY02009.1 - 3.3e-09 36.9 0.0 8.9e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KFY02009.1 - 1e-08 34.5 22.1 0.97 8.3 0.2 8.7 1 1 9 10 10 10 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KFY02009.1 - 2.1e-07 30.6 25.6 0.55 9.5 0.3 9.2 2 1 6 10 10 10 2 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 KFY02009.1 - 4.8e-07 30.3 0.1 1.9e-06 28.4 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KFY02009.1 - 1.8e-05 24.2 0.4 4.7e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins KAP_NTPase PF07693.14 KFY02009.1 - 0.0051 16.1 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 KAP family P-loop domain WXG100 PF06013.12 KFY02009.1 - 0.0066 16.6 14.5 85 3.5 0.0 9.0 9 2 1 10 10 10 0 Proteins of 100 residues with WXG DUF4042 PF13251.6 KFY02009.1 - 0.0073 16.0 4.2 13 5.5 0.0 5.7 1 1 6 8 8 8 0 Domain of unknown function (DUF4042) WD40_like PF17005.5 KFY02009.1 - 0.0082 15.5 10.9 17 4.6 0.8 5.6 2 1 1 6 6 6 0 WD40-like domain AAA PF00004.29 KFY02009.1 - 0.018 15.4 0.1 0.7 10.3 0.0 3.3 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Jnk-SapK_ap_N PF09744.9 KFY02009.1 - 0.04 14.1 0.2 0.092 13.0 0.2 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 AAA_22 PF13401.6 KFY02009.1 - 0.054 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rx_N PF18052.1 KFY02009.1 - 0.088 13.1 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Rx N-terminal domain ATPase_2 PF01637.18 KFY02009.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 KFY02009.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase NYD-SP28_assoc PF14775.6 KFY02009.1 - 0.11 12.6 23.4 74 3.6 0.0 9.7 11 0 0 11 11 10 0 Sperm tail C-terminal domain Phytochelatin PF05023.14 KFY02009.1 - 0.12 11.6 8.2 10 5.3 0.3 5.4 2 1 5 7 7 7 0 Phytochelatin synthase TPR_MLP1_2 PF07926.12 KFY02009.1 - 0.12 12.4 0.6 0.38 10.8 0.6 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_18 PF13238.6 KFY02009.1 - 0.13 12.8 0.0 0.68 10.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain CFEM PF05730.11 KFY02014.1 - 5.3e-14 52.1 13.7 8.5e-14 51.4 13.7 1.3 1 0 0 1 1 1 1 CFEM domain RPN2_C PF18004.1 KFY02015.1 - 8.9e-59 198.0 2.0 1.6e-58 197.2 2.0 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFY02015.1 - 1.9e-40 135.3 20.5 1.3e-08 34.8 0.0 8.2 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFY02015.1 - 2.7e-22 79.0 0.1 5.5e-16 58.7 0.0 5.7 3 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KFY02015.1 - 2.1e-07 31.3 1.0 0.00026 21.4 0.1 5.2 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFY02015.1 - 9.2e-06 25.5 2.8 1.4 9.4 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KFY02015.1 - 0.011 15.8 0.4 0.66 10.0 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 mRNA_triPase PF02940.15 KFY02016.1 - 1.9e-59 201.1 0.1 2.7e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_20 PF00728.22 KFY02017.1 - 2.4e-104 349.5 0.4 6.3e-103 344.9 0.5 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Pkinase PF00069.25 KFY02017.1 - 2.5e-42 145.1 0.0 1.2e-41 142.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02017.1 - 9.7e-31 107.0 0.0 1.4e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glycohydro_20b2 PF14845.6 KFY02017.1 - 1.1e-25 90.9 0.0 2.9e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFY02017.1 - 0.0033 18.2 0.0 0.0074 17.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kinase-like PF14531.6 KFY02017.1 - 0.038 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFY02017.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFY02017.1 - 0.073 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PP1_bind PF15276.6 KFY02017.1 - 1.4 9.3 3.8 0.73 10.2 0.8 2.1 2 0 0 2 2 2 0 Protein phosphatase 1 binding Acyl_transf_3 PF01757.22 KFY02018.1 - 7.6e-29 100.8 27.6 1e-27 97.2 27.6 2.0 1 1 0 1 1 1 1 Acyltransferase family Cation_ATPase_C PF00689.21 KFY02018.1 - 2.6 7.7 7.1 11 5.7 0.2 3.1 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus FMN_dh PF01070.18 KFY02019.1 - 0.16 10.9 0.0 0.19 10.8 0.0 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SET PF00856.28 KFY02020.1 - 7.7e-11 42.7 0.8 2.4e-10 41.0 0.8 2.0 1 1 0 1 1 1 1 SET domain Meleagrin PF08189.11 KFY02020.1 - 0.002 17.7 0.7 0.006 16.3 0.7 1.8 1 0 0 1 1 1 1 Meleagrin/Cygnin family TPR_17 PF13431.6 KFY02020.1 - 0.17 12.3 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.13 KFY02021.1 - 5.2e-30 103.7 0.1 5.2e-30 103.7 0.1 5.6 6 0 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KFY02021.1 - 7.9e-09 35.5 7.7 7.9e-09 35.5 7.7 3.7 3 1 1 4 4 4 1 Centrosome localisation domain of PPC89 NmrA PF05368.13 KFY02021.1 - 1.8e-08 34.2 0.1 5.1e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KFY02021.1 - 2.6e-05 24.2 0.0 8.6e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)H-binding TSC22 PF01166.18 KFY02021.1 - 0.42 10.9 3.2 17 5.8 0.2 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 KFY02021.1 - 0.43 10.8 10.5 0.12 12.6 1.2 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KFY02021.1 - 2.1 8.5 12.5 1.8 8.7 0.9 3.7 3 0 0 3 3 3 0 bZIP transcription factor NRBF2 PF08961.10 KFY02021.1 - 4.7 6.8 16.9 0.095 12.3 1.6 3.3 3 0 0 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator FtsL PF04999.13 KFY02021.1 - 5.5 7.1 8.4 1.8 8.6 1.6 2.8 2 0 0 2 2 2 0 Cell division protein FtsL SKG6 PF08693.10 KFY02022.1 - 1.4e-05 24.4 0.3 1.4e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF1180 PF06679.12 KFY02022.1 - 0.1 13.0 1.9 0.17 12.3 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gly-zipper_Omp PF13488.6 KFY02022.1 - 2.8 8.0 14.6 1.2 9.2 10.7 2.2 2 0 0 2 2 2 0 Glycine zipper HET PF06985.11 KFY02025.1 - 4.1e-06 27.2 0.3 2.9e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 KFY02026.1 - 6.2e-07 29.3 0.2 7.2e-06 25.8 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY02026.1 - 3.5e-06 27.0 0.2 9.5e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KFY02028.1 - 2.2e-48 165.0 0.1 2.8e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFY02028.1 - 1.7e-20 73.3 0.0 6.3e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFY02028.1 - 1.4e-19 70.4 3.2 2.6e-16 59.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY02028.1 - 3.4e-10 39.7 0.0 6.3e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFY02028.1 - 2.1e-08 33.8 2.8 0.0038 16.6 1.4 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFY02028.1 - 5.2e-08 32.4 12.1 0.00065 18.9 3.7 3.8 3 1 0 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFY02028.1 - 8e-07 28.7 7.7 0.00056 19.4 2.6 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFY02028.1 - 0.0013 17.9 0.2 0.078 12.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KFY02028.1 - 0.0022 18.4 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding XdhC_C PF13478.6 KFY02028.1 - 0.021 15.3 0.5 0.61 10.6 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain 3HCDH_N PF02737.18 KFY02028.1 - 0.052 13.4 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFY02028.1 - 0.13 12.5 6.9 8.8 6.6 0.2 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY02028.1 - 0.17 10.9 14.6 0.5 9.4 4.3 4.2 3 1 2 5 5 5 0 FAD binding domain HI0933_like PF03486.14 KFY02028.1 - 0.63 8.7 6.8 4.4 5.9 2.9 3.1 3 1 1 4 4 4 0 HI0933-like protein Trp_halogenase PF04820.14 KFY02028.1 - 1.6 7.5 4.2 1.3 7.8 1.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Gpr1_Fun34_YaaH PF01184.19 KFY02029.1 - 5.7e-33 114.3 23.0 7.4e-33 113.9 23.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ada_Zn_binding PF02805.16 KFY02030.1 - 2.7e-26 91.4 8.5 4.4e-26 90.7 8.5 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KFY02030.1 - 4.5e-08 33.0 0.0 9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KFY02030.1 - 2.6e-06 27.6 0.1 6.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain RIP PF00161.19 KFY02031.1 - 0.011 15.4 0.3 0.017 14.7 0.3 1.3 1 0 0 1 1 1 0 Ribosome inactivating protein MPP6 PF10175.9 KFY02031.1 - 1 9.9 21.1 2.4 8.7 21.0 1.7 1 1 0 1 1 1 0 M-phase phosphoprotein 6 Cu-oxidase_2 PF07731.14 KFY02039.1 - 1.1e-36 125.6 0.4 3.2e-36 124.1 0.4 1.8 1 1 0 1 1 1 1 Multicopper oxidase Cation_efflux PF01545.21 KFY02040.1 - 3.2e-50 170.6 0.0 5e-50 170.0 0.0 1.3 1 1 0 1 1 1 1 Cation efflux family MFS_1 PF07690.16 KFY02042.1 - 4.5e-29 101.5 34.2 4.5e-29 101.5 34.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily PsbT PF01405.17 KFY02043.1 - 0.048 13.5 2.6 0.063 13.1 2.1 1.5 1 1 0 1 1 1 0 Photosystem II reaction centre T protein UCR_Fe-S_N PF10399.9 KFY02043.1 - 2.9 7.3 7.6 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Acyl-CoA_dh_M PF02770.19 KFY02044.1 - 5.3e-06 26.5 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFY02044.1 - 0.038 14.2 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HTH_23 PF13384.6 KFY02045.1 - 8.2e-05 22.3 0.3 0.0002 21.0 0.2 1.9 1 1 1 2 2 2 1 Homeodomain-like domain UPF0122 PF04297.14 KFY02045.1 - 0.0031 17.7 0.0 0.0035 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_38 PF13936.6 KFY02045.1 - 0.0059 16.3 1.9 0.042 13.6 0.1 2.4 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_40 PF14493.6 KFY02045.1 - 0.0077 16.7 0.1 0.0094 16.4 0.1 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 KFY02045.1 - 0.008 16.0 0.1 0.15 11.9 0.0 2.1 1 1 1 2 2 2 1 HTH DNA binding domain Sigma70_r4_2 PF08281.12 KFY02045.1 - 0.0099 15.5 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KFY02045.1 - 0.011 15.2 0.2 0.021 14.4 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_IclR PF09339.10 KFY02045.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.6 KFY02045.1 - 0.053 13.6 0.1 0.12 12.5 0.0 1.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 KFY02045.1 - 0.058 13.5 0.4 0.058 13.5 0.4 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase DUF3562 PF12085.8 KFY02045.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) HTH_3 PF01381.22 KFY02045.1 - 0.075 13.1 0.7 0.35 10.9 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix CENP-B_N PF04218.13 KFY02045.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SpoIIID PF12116.8 KFY02045.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein D TrmB PF01978.19 KFY02045.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TetR_N PF00440.23 KFY02045.1 - 0.11 12.3 0.2 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_29 PF13551.6 KFY02045.1 - 0.13 12.2 0.1 0.37 10.8 0.0 1.8 1 1 1 2 2 2 0 Winged helix-turn helix bZIP_1 PF00170.21 KFY02046.1 - 0.0016 18.5 7.3 0.0029 17.7 7.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFY02046.1 - 0.0051 16.9 6.3 0.01 15.9 6.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper F-box-like PF12937.7 KFY02047.1 - 5e-07 29.5 0.1 1.4e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY02047.1 - 0.00046 20.0 0.1 0.0014 18.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain DDE_3 PF13358.6 KFY02048.1 - 3.7e-12 46.2 0.1 1.3e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFY02048.1 - 5.6e-08 32.9 0.0 2.2e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 Transposase Sigma70_r4_2 PF08281.12 KFY02048.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 KFY02048.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFY02048.1 - 0.0081 15.9 0.2 0.05 13.4 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_40 PF14493.6 KFY02048.1 - 0.0089 16.5 0.1 0.028 14.9 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 KFY02048.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KFY02048.1 - 0.024 14.1 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_antitermQ PF06530.12 KFY02048.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Phage antitermination protein Q zf-RING_UBOX PF13445.6 KFY02048.1 - 0.074 13.1 0.2 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger HTH_7 PF02796.15 KFY02048.1 - 0.12 12.4 0.4 0.71 10.0 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase zf-C3HC4 PF00097.25 KFY02048.1 - 0.13 12.1 0.7 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TetR_N PF00440.23 KFY02048.1 - 0.18 11.6 0.1 0.76 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family MerR PF00376.23 KFY02048.1 - 2 8.3 5.2 1.9 8.3 0.1 2.9 3 0 0 3 3 3 0 MerR family regulatory protein TniQ PF06527.11 KFY02048.1 - 2.2 9.0 5.3 59 4.4 4.1 2.6 2 1 0 2 2 2 0 TniQ Ras PF00071.22 KFY02049.1 - 1.7e-46 157.8 0.0 2.2e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY02049.1 - 4.2e-18 65.7 0.0 6.2e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY02049.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pyr_redox_3 PF13738.6 KFY02050.1 - 3.5e-13 49.5 0.0 2.7e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY02050.1 - 7.1e-12 45.1 0.0 6.9e-09 35.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFY02050.1 - 2e-09 36.5 0.0 2.3e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY02050.1 - 4e-09 36.1 0.1 3.3e-07 29.8 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY02050.1 - 0.00023 20.5 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFY02050.1 - 0.00074 19.7 0.4 0.0022 18.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFY02050.1 - 0.048 14.2 0.0 8.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02050.1 - 0.073 11.8 0.7 3.2 6.4 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KFY02050.1 - 0.096 11.7 0.2 0.22 10.5 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFY02050.1 - 0.11 12.5 0.4 5.3 7.0 0.4 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KFY02050.1 - 0.63 9.6 3.5 1.1 8.8 0.3 2.6 4 0 0 4 4 4 0 FAD dependent oxidoreductase AAA PF00004.29 KFY02063.1 - 9.2e-18 64.9 0.0 1.8e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFY02063.1 - 0.00011 22.6 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFY02063.1 - 0.00023 21.5 0.1 0.0019 18.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFY02063.1 - 0.00028 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFY02063.1 - 0.0054 17.3 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFY02063.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KFY02063.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFY02063.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KFY02063.1 - 0.035 14.3 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KFY02063.1 - 0.04 13.3 0.6 0.075 12.4 0.2 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI HET-s_218-289 PF11558.8 KFY02063.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Het-s 218-289 RNA_helicase PF00910.22 KFY02063.1 - 0.088 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KFY02063.1 - 0.13 12.2 0.1 0.63 9.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zot PF05707.12 KFY02063.1 - 0.15 11.7 0.0 1 9.0 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) DUF4710 PF15828.5 KFY02075.1 - 0.14 12.3 1.3 0.24 11.5 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Chitin_synth_1N PF08407.11 KFY02076.1 - 0.075 13.0 1.1 0.64 10.0 0.0 2.8 3 0 0 3 3 3 0 Chitin synthase N-terminal YabA PF06156.13 KFY02077.1 - 0.03 15.0 0.1 0.039 14.6 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA CENP-H PF05837.12 KFY02077.1 - 0.05 14.0 0.2 0.074 13.5 0.2 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PikAIV_N PF18605.1 KFY02077.1 - 0.21 11.2 7.7 0.51 10.0 7.7 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PHO4 PF01384.20 KFY02079.1 - 2.7e-112 375.1 12.2 3.2e-112 374.9 12.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 KFY02079.1 - 0.019 15.3 0.6 0.13 12.6 0.6 2.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family TMEM43 PF07787.12 KFY02079.1 - 2.3 7.5 4.8 0.52 9.7 0.6 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 EspB PF05802.11 KFY02080.1 - 0.004 17.2 1.9 0.018 15.0 0.8 2.3 2 0 0 2 2 2 1 Enterobacterial EspB protein SKA2 PF16740.5 KFY02080.1 - 0.18 11.6 0.9 33 4.3 0.2 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 YlbD_coat PF14071.6 KFY02080.1 - 0.74 10.1 2.6 1.3 9.3 0.4 2.4 2 1 1 3 3 3 0 Putative coat protein FMO-like PF00743.19 KFY02082.1 - 2.2e-17 62.7 0.4 5.9e-17 61.3 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFY02082.1 - 4.3e-11 42.9 0.0 1.2e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY02082.1 - 2.4e-10 40.1 0.0 9.3e-08 31.6 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY02082.1 - 3.7e-07 30.1 2.4 1.3e-05 25.0 0.4 3.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFY02082.1 - 6.6e-07 28.9 1.7 3.7e-06 26.4 1.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY02082.1 - 2.3e-05 23.7 0.0 0.00017 20.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFY02082.1 - 0.0021 17.4 0.9 0.0033 16.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFY02082.1 - 0.0059 16.6 0.1 0.24 11.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KFY02082.1 - 0.13 11.6 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Mqo PF06039.15 KFY02082.1 - 0.27 9.7 0.4 1.5 7.3 0.1 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.16 KFY02083.1 - 6e-23 81.3 23.6 1.1e-22 80.5 23.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 KFY02084.1 - 6.9e-31 107.4 26.6 6.9e-31 107.4 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.20 KFY02085.1 - 2.1e-60 204.8 0.0 2.8e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ABC_membrane PF00664.23 KFY02086.1 - 2.6e-42 145.4 11.3 3.2e-42 145.1 11.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFY02086.1 - 6.3e-35 120.7 0.0 1.1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KFY02086.1 - 3.3e-06 26.7 0.0 0.0012 18.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFY02086.1 - 5.9e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFY02086.1 - 0.00031 20.7 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFY02086.1 - 0.00065 20.0 0.1 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFY02086.1 - 0.0011 19.1 0.0 0.078 13.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY02086.1 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 KFY02086.1 - 0.0044 17.0 0.0 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFY02086.1 - 0.0075 16.7 0.0 0.045 14.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFY02086.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFY02086.1 - 0.015 15.0 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFY02086.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain GPAT_N PF14829.6 KFY02086.1 - 0.023 14.7 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_25 PF13481.6 KFY02086.1 - 0.03 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFY02086.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 KFY02086.1 - 0.033 13.1 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 KFY02086.1 - 0.035 13.6 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFY02086.1 - 0.042 14.1 0.1 0.12 12.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY02086.1 - 0.084 13.4 0.0 0.41 11.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 KFY02086.1 - 0.09 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MBOAT_2 PF13813.6 KFY02086.1 - 0.12 12.6 0.2 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family AAA_30 PF13604.6 KFY02086.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFY02086.1 - 0.17 11.8 0.3 0.67 9.9 0.0 2.2 3 0 0 3 3 1 0 NACHT domain SbcCD_C PF13558.6 KFY02086.1 - 0.2 11.9 0.4 2.3 8.5 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Metallophos PF00149.28 KFY02087.1 - 1.6e-14 54.9 2.3 2.7e-14 54.2 2.3 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFY02087.1 - 4.6e-08 33.4 0.0 3e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.9 KFY02088.1 - 0.0092 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) AAA PF00004.29 KFY02090.1 - 3e-27 95.6 0.0 5.7e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY02090.1 - 3e-06 27.1 0.0 9.9e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KFY02090.1 - 7e-06 25.9 0.1 0.00025 20.8 0.1 2.2 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KFY02090.1 - 0.00041 19.7 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFY02090.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFY02090.1 - 0.0005 20.5 1.5 0.0025 18.2 1.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFY02090.1 - 0.0017 18.7 0.0 0.0045 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 KFY02090.1 - 0.0031 17.6 0.0 0.03 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KFY02090.1 - 0.0049 16.5 0.5 0.015 14.9 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY02090.1 - 0.0093 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFY02090.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFY02090.1 - 0.011 16.0 1.6 0.064 13.5 1.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KFY02090.1 - 0.017 15.1 0.3 0.042 13.8 0.3 1.7 1 1 0 1 1 1 0 NACHT domain ATPase PF06745.13 KFY02090.1 - 0.017 14.5 0.5 2.1 7.6 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.6 KFY02090.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY02090.1 - 0.019 15.5 0.0 0.043 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain CdiI_2 PF18593.1 KFY02090.1 - 0.025 15.2 0.0 0.31 11.7 0.0 2.5 2 0 0 2 2 2 0 CdiI immunity protein IstB_IS21 PF01695.17 KFY02090.1 - 0.033 13.9 0.1 0.19 11.5 0.0 2.0 1 1 0 2 2 2 0 IstB-like ATP binding protein ArsA_ATPase PF02374.15 KFY02090.1 - 0.062 12.5 0.3 0.2 10.8 0.2 1.8 1 1 1 2 2 2 0 Anion-transporting ATPase TsaE PF02367.17 KFY02090.1 - 0.075 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFY02090.1 - 0.081 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KFY02090.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Cytokin_check_N PF10407.9 KFY02091.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Velvet PF11754.8 KFY02092.1 - 9e-87 291.1 2.5 9e-87 291.1 2.5 2.4 2 1 0 2 2 2 2 Velvet factor Fer2_3 PF13085.6 KFY02093.1 - 1.9e-30 105.1 0.0 3.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFY02093.1 - 4.3e-09 36.8 6.3 4.3e-09 36.8 6.3 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFY02093.1 - 1.1e-07 32.2 8.6 1.1e-07 32.2 8.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFY02093.1 - 5.8e-07 29.5 3.4 5.8e-07 29.5 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KFY02093.1 - 0.0055 17.3 6.5 0.0055 17.3 6.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KFY02093.1 - 0.0092 15.9 0.4 0.0092 15.9 0.4 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KFY02093.1 - 0.87 9.8 12.5 1.2 9.3 9.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFY02093.1 - 1.5 9.1 7.8 0.58 10.4 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Evr1_Alr PF04777.13 KFY02094.1 - 3.9e-27 94.6 0.1 5.4e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KFY02094.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 R3H PF01424.22 KFY02095.1 - 4.7e-17 61.7 0.1 8.4e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-RING_2 PF13639.6 KFY02095.1 - 0.00013 22.2 5.7 0.00013 22.2 5.7 7.3 4 2 2 6 6 6 1 Ring finger domain zf-NF-X1 PF01422.17 KFY02095.1 - 0.00077 19.5 12.7 0.00077 19.5 12.7 8.5 9 1 1 10 10 10 4 NF-X1 type zinc finger Zn_clus PF00172.18 KFY02096.1 - 1.7e-06 28.0 10.2 3.4e-06 27.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_9 PF13371.6 KFY02096.1 - 0.00024 21.2 1.2 0.22 11.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFY02096.1 - 0.0043 17.8 0.9 0.093 13.6 0.1 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFY02096.1 - 0.025 14.4 1.2 2.2 8.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KFY02096.1 - 0.026 13.4 0.2 0.05 12.4 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_11 PF13414.6 KFY02096.1 - 0.049 13.3 0.3 3 7.6 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 KFY02096.1 - 0.11 13.0 4.3 9.1 6.9 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02096.1 - 0.27 11.5 5.3 1.9 8.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 KFY02098.1 - 7.7e-25 88.3 0.0 1.3e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY02098.1 - 2.1e-19 70.3 0.0 2.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_61 PF03443.14 KFY02099.1 - 1.5e-57 194.8 0.9 2.3e-57 194.3 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_4 PF01063.19 KFY02099.1 - 9.5e-23 81.2 0.0 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TPR_12 PF13424.6 KFY02114.1 - 1.6e-13 50.7 9.6 5.4e-07 29.8 0.1 6.0 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFY02114.1 - 8.4e-09 35.0 6.6 0.00057 19.7 0.2 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KFY02114.1 - 2.2e-07 30.3 0.0 0.0064 15.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain CorA PF01544.18 KFY02114.1 - 1.9e-05 24.2 0.1 4.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.7 KFY02114.1 - 0.00026 21.7 0.0 0.0012 19.5 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KFY02114.1 - 0.0048 17.3 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 KFY02114.1 - 0.0069 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein TPR_16 PF13432.6 KFY02114.1 - 0.013 16.1 1.1 9.9 6.9 0.0 4.2 4 1 1 5 5 3 0 Tetratricopeptide repeat DUF676 PF05057.14 KFY02114.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_22 PF13401.6 KFY02114.1 - 0.042 14.1 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_20 PF14561.6 KFY02114.1 - 0.059 13.7 0.5 18 5.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFY02114.1 - 0.11 12.3 1.3 71 3.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY02114.1 - 0.77 10.1 3.8 60 4.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02114.1 - 0.81 10.0 10.5 58 4.2 0.5 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat HAD_2 PF13419.6 KFY02115.1 - 5.6e-15 55.9 0.0 1.1e-14 55.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY02115.1 - 2.4e-05 24.3 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFY02115.1 - 0.0019 18.5 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CN_hydrolase PF00795.22 KFY02117.1 - 1.5e-12 47.4 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_18 PF00704.28 KFY02118.1 - 1.7e-45 156.1 1.0 3.7e-45 155.0 1.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFY02118.1 - 1.3e-05 25.2 0.1 0.011 15.7 0.2 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KFY02118.1 - 0.00029 21.3 7.8 0.00029 21.3 7.8 3.3 2 0 0 2 2 2 1 Chitin recognition protein DUF3015 PF11220.8 KFY02119.1 - 0.41 10.5 2.1 1.8 8.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3015) WSC PF01822.19 KFY02120.1 - 4.5e-45 151.7 38.3 1.9e-16 60.0 7.4 3.6 3 0 0 3 3 3 3 WSC domain LysM PF01476.20 KFY02120.1 - 0.0011 19.0 1.2 0.0024 17.9 0.5 1.9 2 0 0 2 2 2 1 LysM domain Chromo PF00385.24 KFY02122.1 - 1e-17 63.7 3.9 2.1e-08 33.9 1.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_6 PF13921.6 KFY02122.1 - 0.00012 22.3 0.6 0.00031 20.9 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFY02122.1 - 0.002 18.3 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mtf2_C PF14061.6 KFY02122.1 - 1.1 9.5 2.9 3.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Telomerase_RBD PF12009.8 KFY02124.1 - 6e-50 168.8 0.1 1.3e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KFY02124.1 - 2.6e-14 53.3 0.0 1.6e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.20 KFY02125.1 - 2.3e-33 116.0 0.4 9.1e-33 114.0 0.0 2.2 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KFY02125.1 - 4.5e-07 29.8 1.7 4.5e-07 29.8 1.7 2.0 2 0 0 2 2 2 1 BAR domain Hydrolase_4 PF12146.8 KFY02126.1 - 6.3e-20 71.5 0.0 9.4e-14 51.3 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY02126.1 - 1.1e-12 48.2 0.0 3e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KFY02126.1 - 5.1e-08 32.0 0.1 0.0051 15.5 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KFY02126.1 - 3.1e-06 26.8 0.0 1.6e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 KFY02126.1 - 5.8e-06 26.1 0.0 2e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KFY02126.1 - 0.00016 21.3 0.0 0.05 13.2 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family BAAT_C PF08840.11 KFY02126.1 - 0.00018 21.5 0.0 0.0077 16.2 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.12 KFY02126.1 - 0.00022 20.3 0.1 0.00031 19.8 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 KFY02126.1 - 0.00023 21.0 0.5 0.082 12.7 0.2 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFY02126.1 - 0.00033 21.3 0.0 0.00062 20.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFY02126.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFY02126.1 - 0.002 17.7 0.0 0.75 9.3 0.0 2.6 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KFY02126.1 - 0.0073 16.0 0.4 0.11 12.2 0.1 2.3 2 1 1 3 3 3 1 PGAP1-like protein Abhydrolase_5 PF12695.7 KFY02126.1 - 0.017 14.9 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KFY02126.1 - 0.059 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.12 KFY02126.1 - 0.07 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 LIDHydrolase PF10230.9 KFY02126.1 - 0.09 12.3 0.0 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase zf-LYAR PF08790.11 KFY02127.1 - 5.4e-15 55.0 1.4 5.4e-15 55.0 1.4 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-ACC PF17848.1 KFY02127.1 - 0.19 11.8 0.4 0.37 10.9 0.4 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-TRAF PF02176.18 KFY02127.1 - 1.3 9.8 5.0 0.16 12.7 0.8 1.7 2 0 0 2 2 2 0 TRAF-type zinc finger DUF1117 PF06547.12 KFY02127.1 - 5.4 7.6 10.1 0.13 12.8 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Pex2_Pex12 PF04757.14 KFY02128.1 - 7.7e-43 146.7 5.7 9.9e-43 146.3 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KFY02128.1 - 2.6e-11 43.1 8.3 4.3e-11 42.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFY02128.1 - 6.5e-11 42.4 9.0 1.1e-10 41.6 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFY02128.1 - 9.3e-10 38.2 6.4 1.5e-09 37.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFY02128.1 - 1.3e-08 34.5 8.8 2e-08 33.9 8.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY02128.1 - 5.5e-07 29.5 7.9 1.2e-06 28.5 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFY02128.1 - 6.4e-07 29.2 5.2 1.1e-06 28.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFY02128.1 - 2.2e-06 27.7 7.5 3.9e-06 26.9 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFY02128.1 - 4.9e-06 26.7 8.9 8.6e-06 25.9 8.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFY02128.1 - 5e-05 23.1 9.5 8.2e-05 22.4 9.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFY02128.1 - 0.0026 17.9 8.2 0.0043 17.1 8.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KFY02128.1 - 0.012 15.5 1.1 0.023 14.5 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFY02128.1 - 0.017 15.0 4.8 0.036 13.9 4.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFY02128.1 - 0.093 12.5 6.5 0.21 11.4 6.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFY02128.1 - 0.77 9.6 3.3 1.9 8.3 3.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger Imm17 PF15562.6 KFY02128.1 - 0.94 9.4 3.0 0.45 10.4 0.2 1.9 2 0 0 2 2 2 0 Immunity protein 17 EXS PF03124.14 KFY02129.1 - 2.8e-109 365.4 11.2 3.2e-109 365.2 11.2 1.0 1 0 0 1 1 1 1 EXS family FUSC_2 PF13515.6 KFY02130.1 - 3.1e-13 50.0 19.2 5.8e-13 49.1 19.2 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFY02130.1 - 4.6e-10 39.7 0.3 1.6e-08 34.7 0.2 2.8 2 1 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KFY02130.1 - 4.8e-08 32.5 0.0 1.9e-05 23.9 0.0 2.8 2 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal EST1_DNA_bind PF10373.9 KFY02133.1 - 5.7e-07 29.3 1.2 5.7e-07 29.3 1.2 3.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Tudor_RapA PF18337.1 KFY02133.1 - 0.098 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain Peptidase_C14 PF00656.22 KFY02134.1 - 2.7e-31 109.4 0.0 4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.26 KFY02134.1 - 6.7e-07 29.4 3.7 0.0087 16.5 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY02134.1 - 0.00027 21.5 2.0 0.37 11.8 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Peptidase_C13 PF01650.18 KFY02134.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.7 1 1 0 1 1 1 0 Peptidase C13 family zf-BED PF02892.15 KFY02134.1 - 0.11 12.5 0.3 0.51 10.4 0.2 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_12 PF18658.1 KFY02134.1 - 0.12 11.9 0.2 0.37 10.4 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type Glyco_hydro_18 PF00704.28 KFY02144.1 - 5e-47 161.1 3.1 8.8e-47 160.3 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFY02144.1 - 1.3e-05 25.2 0.1 0.012 15.7 0.2 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KFY02144.1 - 0.0003 21.2 8.0 0.0003 21.2 8.0 3.1 2 0 0 2 2 2 1 Chitin recognition protein WD40 PF00400.32 KFY02146.1 - 1.4e-50 168.2 18.6 1.9e-08 34.8 0.4 9.2 8 0 0 8 8 8 6 WD domain, G-beta repeat WSC PF01822.19 KFY02146.1 - 1.3e-44 150.3 39.7 4.7e-17 61.9 8.7 3.6 3 0 0 3 3 3 3 WSC domain ANAPC4_WD40 PF12894.7 KFY02146.1 - 1.3e-12 47.8 0.1 0.00071 19.8 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY02146.1 - 4.3e-07 29.0 1.8 0.0013 17.5 0.5 3.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFY02146.1 - 0.00019 20.3 0.0 0.061 12.1 0.0 2.7 3 0 0 3 3 3 2 Nup133 N terminal like LysM PF01476.20 KFY02146.1 - 0.00038 20.4 0.3 0.0059 16.6 0.5 2.5 2 0 0 2 2 2 1 LysM domain PspB PF06667.12 KFY02147.1 - 0.092 12.8 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B PMP1_2 PF08114.11 KFY02147.1 - 0.29 10.9 4.4 0.49 10.2 4.4 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Fungal_trans PF04082.18 KFY02148.1 - 1e-12 47.7 0.7 1.5e-12 47.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFY02148.1 - 0.00022 21.5 1.7 0.00054 20.3 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY02148.1 - 0.0017 19.0 1.0 0.0051 17.5 1.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger K-box PF01486.17 KFY02148.1 - 0.0037 17.4 0.3 0.99 9.6 0.0 2.7 2 0 0 2 2 2 2 K-box region zf-C2H2_jaz PF12171.8 KFY02148.1 - 0.16 12.3 0.4 0.54 10.6 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sugar_tr PF00083.24 KFY02149.1 - 1.5e-84 284.5 33.2 1.8e-84 284.2 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02149.1 - 2.3e-32 112.3 32.7 2.3e-32 112.3 32.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY02149.1 - 9.2e-05 21.0 2.9 9.2e-05 21.0 2.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TM_GPCR_Srw PF10324.9 KFY02149.1 - 0.014 14.7 1.8 0.014 14.7 1.8 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF3413 PF11893.8 KFY02149.1 - 0.025 13.7 0.2 0.025 13.7 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) Mannosidase_ig PF17786.1 KFY02150.1 - 3e-09 37.4 0.0 3.2e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFY02150.1 - 1.7e-07 31.9 0.1 5.3e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFY02150.1 - 0.0027 16.9 0.2 0.009 15.2 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFY02150.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Lipase_GDSL_2 PF13472.6 KFY02151.1 - 7.3e-10 39.5 3.0 1e-09 39.0 3.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY02151.1 - 2.9e-06 27.4 1.0 4.1e-06 26.9 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GMC_oxred_N PF00732.19 KFY02154.1 - 1.1e-64 218.7 0.0 1.4e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY02154.1 - 8.8e-30 104.1 0.0 1.6e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFY02154.1 - 1.8e-05 24.0 0.3 3.4e-05 23.1 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFY02154.1 - 7.6e-05 22.0 0.5 0.12 11.5 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFY02154.1 - 0.0081 15.4 0.2 0.021 14.1 0.2 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFY02154.1 - 0.043 13.0 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFY02154.1 - 0.047 12.5 0.1 0.069 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KFY02154.1 - 0.072 13.3 0.2 0.2 11.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY02154.1 - 0.092 12.3 2.1 0.76 9.3 2.2 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Vint PF14623.6 KFY02155.1 - 1.2e-55 187.9 0.0 2.4e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KFY02155.1 - 1e-19 70.4 0.0 2.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KFY02155.1 - 3.2e-18 66.6 0.0 6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFY02155.1 - 2.8e-14 53.7 0.1 8.7e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFY02155.1 - 3.7e-11 43.2 0.0 2.9e-09 37.1 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFY02155.1 - 0.019 14.3 0.0 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein FA_desaturase PF00487.24 KFY02156.1 - 1.4e-13 51.3 17.3 2.9e-13 50.2 16.8 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Pro_CA PF00484.19 KFY02159.1 - 4.3e-50 170.0 0.1 5.5e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 KFY02159.1 - 0.0062 15.8 0.0 0.0081 15.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily TauD PF02668.16 KFY02160.1 - 1e-52 179.6 0.9 1.3e-52 179.3 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NTP_transf_9 PF04248.12 KFY02161.1 - 7.9e-30 102.6 1.9 8.2e-26 89.7 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) HTH_17 PF12728.7 KFY02161.1 - 0.016 15.4 0.0 0.065 13.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TRP PF06011.12 KFY02162.1 - 1.1e-161 538.3 25.0 2.1e-161 537.4 25.0 1.5 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFY02162.1 - 5.8e-39 133.6 0.6 1.1e-38 132.7 0.6 1.5 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.16 KFY02162.1 - 5.4e-21 74.9 37.7 3.7e-19 68.8 27.5 4.8 3 2 1 4 4 4 2 Major Facilitator Superfamily Ac76 PF05814.11 KFY02162.1 - 0.13 12.3 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) MitoNEET_N PF10660.9 KFY02162.1 - 5 7.2 5.4 3 7.9 0.1 3.0 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus SMI1_KNR4 PF09346.10 KFY02163.1 - 4.8e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 KFY02163.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall SUKH_6 PF14568.6 KFY02163.1 - 0.061 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Nucleoside_tran PF01733.18 KFY02165.1 - 6.6e-25 88.1 4.2 7.8e-25 87.9 4.2 1.0 1 0 0 1 1 1 1 Nucleoside transporter cobW PF02492.19 KFY02166.1 - 1.5e-45 155.0 2.7 3.1e-34 118.1 0.1 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain A_deaminase PF00962.22 KFY02166.1 - 6.9e-39 134.1 0.0 1.3e-38 133.2 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase CobW_C PF07683.14 KFY02166.1 - 1.8e-20 72.7 0.1 6.1e-15 54.9 0.0 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KFY02166.1 - 0.0022 17.9 0.1 0.0072 16.2 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 KFY02166.1 - 0.16 11.7 0.0 0.51 10.0 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KFY02166.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain GLEYA PF10528.9 KFY02167.1 - 4.5e-27 94.3 0.4 4.5e-27 94.3 0.4 1.7 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 KFY02167.1 - 4.7e-08 33.0 0.0 7.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Stig1 PF04885.13 KFY02167.1 - 0.0069 16.9 23.6 0.011 16.3 23.6 1.2 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 GMC_oxred_N PF00732.19 KFY02168.1 - 6.6e-29 101.2 0.0 2e-25 89.8 0.0 2.7 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY02168.1 - 1.6e-27 96.8 0.0 3e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 KFY02168.1 - 7e-08 31.8 65.8 3.5e-07 29.5 41.6 3.7 2 2 1 3 3 3 2 Major Facilitator Superfamily NAD_binding_8 PF13450.6 KFY02168.1 - 3.3e-05 24.0 1.1 9.4e-05 22.6 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KFY02168.1 - 0.0061 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KFY02168.1 - 0.0071 15.5 1.9 0.012 14.8 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY02168.1 - 0.0083 15.4 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02168.1 - 0.037 12.7 0.4 0.055 12.2 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KFY02168.1 - 0.061 12.4 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PhoPQ_related PF10142.9 KFY02168.1 - 0.2 10.3 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Pyr_redox_3 PF13738.6 KFY02168.1 - 1.1 8.5 3.2 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase APH PF01636.23 KFY02169.1 - 6.8e-12 45.8 0.0 4e-11 43.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFY02169.1 - 0.004 16.1 0.0 0.33 9.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KFY02169.1 - 0.14 11.3 0.0 2.1 7.5 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase MapZ_EC1 PF18041.1 KFY02170.1 - 0.019 15.2 1.7 0.12 12.6 1.0 2.0 1 1 1 2 2 2 0 MapZ extracellular domain 1 aGPT-Pplase2 PF18724.1 KFY02170.1 - 0.084 12.6 0.1 0.09 12.5 0.1 1.1 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 Lectin_leg-like PF03388.13 KFY02171.1 - 2.4e-66 223.4 0.0 3.5e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFY02171.1 - 4.9e-07 30.0 0.1 7.4e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KFY02171.1 - 1.5e-05 24.7 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 KFY02171.1 - 0.043 13.7 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 KFY02172.1 - 4.9e-24 83.8 2.2 6.1e-24 83.4 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3361 PF11841.8 KFY02172.1 - 0.043 13.8 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Abhydrolase_4 PF08386.10 KFY02172.1 - 0.099 12.8 0.0 1.4 9.1 0.0 2.1 1 1 0 1 1 1 0 TAP-like protein DDE_1 PF03184.19 KFY02175.1 - 1.6e-29 102.8 0.0 3.1e-29 101.9 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.6 KFY02175.1 - 6.7e-07 29.2 0.0 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFY02175.1 - 0.0028 17.7 0.0 0.0092 16.0 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 KFY02175.1 - 0.0082 15.9 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Catalase-rel PF06628.12 KFY02176.1 - 1.7e-12 47.4 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KFY02176.1 - 1.9e-10 40.6 0.0 3.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KFY02176.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family VWA_CoxE PF05762.14 KFY02176.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF3435 PF11917.8 KFY02177.1 - 1.9e-14 53.4 0.0 3.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.24 KFY02177.1 - 1.6e-10 40.7 4.4 5.9e-07 29.3 1.2 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ADIP PF11559.8 KFY02177.1 - 0.072 13.2 2.9 0.25 11.4 2.9 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TT_ORF2 PF02957.15 KFY02177.1 - 0.093 13.6 0.5 0.25 12.3 0.5 1.7 1 0 0 1 1 1 0 TT viral ORF2 Phage_integrase PF00589.22 KFY02177.1 - 0.11 12.3 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Phage integrase family DUF3435 PF11917.8 KFY02188.1 - 7e-28 97.7 1.3 9.3e-28 97.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-met PF12874.7 KFY02188.1 - 0.054 13.9 0.4 0.17 12.3 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KFY02188.1 - 0.71 10.4 6.9 20 5.9 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY02188.1 - 10 7.3 6.6 91 4.3 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Filament PF00038.21 KFY02189.1 - 4.9 6.6 30.8 0.012 15.2 14.0 3.0 2 1 1 3 3 3 0 Intermediate filament protein APH PF01636.23 KFY02190.1 - 5.9e-11 42.7 0.0 2.3e-10 40.8 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4607 PF15380.6 KFY02190.1 - 0.063 12.8 0.5 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) SAM_1 PF00536.30 KFY02192.1 - 1.6e-09 38.0 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFY02192.1 - 0.00093 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box PF00505.19 KFY02193.1 - 6.6e-11 42.5 0.1 1.2e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 KFY02193.1 - 8.6e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KFY02193.1 - 1.1e-08 35.5 0.2 2.4e-08 34.5 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 KFY02193.1 - 5.9e-08 32.7 0.0 1.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ub-Mut7C PF14451.6 KFY02199.1 - 0.21 11.4 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Mut7-C ubiquitin DAO PF01266.24 KFY02200.1 - 0.041 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFY02200.1 - 0.18 11.8 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Chromate_transp PF02417.15 KFY02201.1 - 5.3e-10 39.6 5.3 7.1e-10 39.2 5.3 1.1 1 0 0 1 1 1 1 Chromate transporter His_Phos_1 PF00300.22 KFY02202.1 - 1.9e-14 53.8 0.0 8.9e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) FMO-like PF00743.19 KFY02212.1 - 1.2e-08 33.8 0.1 2.9e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFY02212.1 - 4.2e-08 32.7 0.1 3.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFY02212.1 - 1.3e-07 31.7 0.0 3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFY02212.1 - 3.4e-06 26.5 0.0 8.9e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY02212.1 - 3.6e-05 23.1 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 KFY02212.1 - 0.00059 19.9 5.5 0.0017 18.4 5.4 1.8 1 1 0 1 1 1 1 bZIP transcription factor NAD_binding_9 PF13454.6 KFY02212.1 - 0.00085 19.3 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFY02212.1 - 0.0051 16.4 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFY02212.1 - 0.0066 15.7 0.0 0.051 12.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KFY02212.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain bZIP_2 PF07716.15 KFY02212.1 - 3.3 7.9 11.1 9.9 6.3 1.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper FMN_red PF03358.15 KFY02223.1 - 5.5e-07 29.4 0.1 1e-06 28.6 0.0 1.4 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Peptidase_M43 PF05572.13 KFY02283.1 - 1.1e-15 57.8 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 KFY02283.1 - 0.00073 19.4 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 KFY02283.1 - 0.00089 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFY02283.1 - 0.016 15.3 1.8 0.03 14.5 1.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 Sugar_tr PF00083.24 KFY02285.1 - 2.5e-83 280.5 22.2 2.9e-83 280.3 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02285.1 - 1.7e-20 73.3 29.0 1.7e-20 73.3 29.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily IBV_3C PF03620.13 KFY02285.1 - 4.4 7.9 6.5 6.5 7.3 0.0 3.2 3 0 0 3 3 3 0 IBV 3C protein Sulfatase PF00884.23 KFY02286.1 - 2e-67 227.8 0.1 2.7e-67 227.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFY02286.1 - 9.4e-21 74.0 5.4 5.1e-20 71.7 5.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFY02286.1 - 2.7e-10 40.4 1.1 0.00046 19.9 0.0 2.6 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFY02286.1 - 0.025 13.2 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RepL PF05732.11 KFY02286.1 - 0.088 12.2 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Romo1 PF10247.9 KFY02302.1 - 1e-27 96.3 15.7 1.4e-27 95.8 15.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFY02302.1 - 0.0054 17.1 5.5 0.0073 16.7 5.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3435 PF11917.8 KFY02309.1 - 1.3e-05 24.3 0.8 4.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) TPR_10 PF13374.6 KFY02338.1 - 2.6e-110 357.7 19.4 4.6e-10 39.0 0.1 12.5 11 1 1 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.6 KFY02338.1 - 5.2e-86 283.0 40.3 2.8e-13 49.9 0.6 10.3 2 2 8 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02338.1 - 1.4e-25 87.4 29.9 0.07 13.2 0.1 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 KFY02338.1 - 2e-25 87.3 20.0 0.61 10.6 0.0 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.28 KFY02338.1 - 3.2e-17 61.5 23.5 0.02 14.7 0.2 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02338.1 - 4.3e-15 54.5 21.1 0.64 10.3 0.1 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_4 PF07721.14 KFY02338.1 - 2.5e-14 52.3 13.4 0.51 11.1 0.0 10.7 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFY02338.1 - 3.3e-13 48.7 20.5 0.2 12.0 0.2 11.4 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY02338.1 - 7.7e-12 45.5 22.9 0.27 11.7 0.0 9.7 3 2 7 10 10 10 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KFY02338.1 - 7.8e-08 31.9 0.2 1.7e-07 30.8 0.2 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_16 PF13432.6 KFY02338.1 - 2.3e-07 31.4 0.5 33 5.2 0.0 8.1 9 1 0 9 9 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFY02338.1 - 3.4e-06 26.9 15.2 1.3 9.1 0.2 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 KFY02338.1 - 0.00025 20.3 0.0 0.00054 19.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain LRR_1 PF00560.33 KFY02338.1 - 0.00062 20.0 0.0 2.7e+02 2.8 0.0 7.9 11 0 0 11 11 7 0 Leucine Rich Repeat LRR_8 PF13855.6 KFY02338.1 - 0.002 17.9 6.1 74 3.2 0.0 7.6 10 0 0 10 10 9 0 Leucine rich repeat Urocanase_N PF17391.2 KFY02338.1 - 0.009 15.7 0.0 77 3.0 0.0 5.8 7 0 0 7 7 7 0 Urocanase N-terminal domain TPR_20 PF14561.6 KFY02338.1 - 0.066 13.5 19.7 29 5.1 0.7 8.3 1 1 3 6 6 6 0 Tetratricopeptide repeat FBA PF04300.13 KFY02338.1 - 0.083 12.6 6.9 2.5 7.8 0.4 3.8 1 1 1 3 3 3 0 F-box associated region UBA_e1_thiolCys PF10585.9 KFY02338.1 - 0.23 11.4 1.6 15 5.4 0.5 3.2 2 1 2 4 4 3 0 Ubiquitin-activating enzyme active site DUF4363 PF14276.6 KFY02338.1 - 6.3 7.0 9.2 69 3.6 0.1 5.1 2 1 4 6 6 6 0 Domain of unknown function (DUF4363) CorA PF01544.18 KFY02339.1 - 1.9e-13 50.4 0.3 2.3e-13 50.1 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 KFY02339.1 - 0.0048 15.7 0.1 0.0055 15.5 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) AA_permease_N PF08403.10 KFY02339.1 - 0.039 13.5 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal Phage_holin_3_6 PF07332.11 KFY02339.1 - 0.04 14.0 0.2 0.074 13.1 0.1 1.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III V-SNARE_C PF12352.8 KFY02339.1 - 0.1 12.9 3.4 0.14 12.5 0.4 2.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus YadA_stalk PF05662.14 KFY02344.1 - 6.4e-07 29.6 9.8 2.1 8.8 0.1 5.3 5 0 0 5 5 5 4 Coiled stalk of trimeric autotransporter adhesin KIP1 PF07765.12 KFY02344.1 - 0.00064 19.8 0.0 26 5.0 0.0 4.1 4 0 0 4 4 4 0 KIP1-like protein Cornifin PF02389.15 KFY02344.1 - 0.0013 19.0 2.8 0.43 10.8 2.8 2.5 1 1 0 1 1 1 1 Cornifin (SPRR) family U1snRNP70_N PF12220.8 KFY02344.1 - 0.0067 17.0 0.7 7.7 7.2 0.3 3.5 1 1 3 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Fez1 PF06818.15 KFY02344.1 - 0.01 16.3 3.5 74 3.7 0.0 4.1 4 1 0 4 4 4 0 Fez1 Syntaxin PF00804.25 KFY02344.1 - 0.014 15.1 1.4 2 8.0 0.4 2.6 1 1 2 3 3 3 0 Syntaxin NOG1_N PF17835.1 KFY02344.1 - 0.032 14.2 0.3 6.6 6.7 0.1 3.6 4 0 0 4 4 4 0 NOG1 N-terminal helical domain DUF2277 PF10041.9 KFY02344.1 - 0.037 14.3 18.3 2.7 8.4 0.3 4.7 2 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2277) DUF2862 PF11061.8 KFY02344.1 - 0.056 13.3 0.3 11 5.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2862) Chisel PF15355.6 KFY02344.1 - 0.059 13.6 12.0 0.21 11.9 2.2 2.9 1 1 2 3 3 3 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF3418 PF11898.8 KFY02344.1 - 0.066 11.9 1.5 0.15 10.7 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3418) DUF1917 PF08939.10 KFY02344.1 - 1.7 8.5 5.0 3.3 7.5 0.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1917) CLPTM1 PF05602.12 KFY02345.1 - 7e-152 506.4 0.0 8.3e-152 506.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.14 KFY02346.1 - 1.1e-29 103.2 0.0 1.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KFY02346.1 - 7.1e-05 22.4 0.5 0.0044 16.6 0.0 2.7 2 1 1 3 3 3 2 SLOG cluster4 family Vps55 PF04133.14 KFY02347.1 - 1.1e-45 154.4 7.2 1.2e-45 154.2 7.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 KFY02348.1 - 1.9e-46 158.0 0.1 2.3e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFY02348.1 - 7.1e-11 41.6 0.2 1.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chorismate_bind PF00425.18 KFY02349.1 - 3.4e-66 223.4 0.0 2.1e-37 129.1 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KFY02349.1 - 4.2e-22 78.9 0.0 3.8e-20 72.5 0.0 2.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KFY02349.1 - 3e-12 46.9 0.0 7.1e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KFY02349.1 - 0.0084 15.9 0.6 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 Peptidase C26 EamA PF00892.20 KFY02350.1 - 1.8e-05 24.9 30.7 0.00019 21.6 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family Thioredoxin PF00085.20 KFY02351.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFY02351.1 - 1.5e-05 24.1 0.1 1.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Mt_ATP-synt_B PF05405.14 KFY02351.1 - 0.086 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ARD PF03079.14 KFY02352.1 - 3.1e-43 147.7 0.1 3.1e-43 147.7 0.1 1.7 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.25 KFY02352.1 - 6.1e-29 100.9 0.0 9.3e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02352.1 - 2.9e-19 69.6 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cupin_2 PF07883.11 KFY02352.1 - 3.5e-08 33.1 0.0 8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain KR PF08659.10 KFY02352.1 - 3.7e-07 30.2 0.0 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 KR domain AraC_binding PF02311.19 KFY02352.1 - 2.4e-05 24.3 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Epimerase PF01370.21 KFY02352.1 - 4.7e-05 23.0 0.1 0.00012 21.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GIDA PF01134.22 KFY02353.1 - 7.2e-160 532.4 0.0 1e-159 531.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFY02353.1 - 7.2e-66 222.4 0.0 1.1e-65 221.8 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KFY02353.1 - 2.1e-06 27.4 0.1 3.7e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFY02353.1 - 1.4e-05 24.5 0.3 5.5e-05 22.5 0.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY02353.1 - 0.00077 18.6 1.7 0.0013 17.8 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFY02353.1 - 0.008 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFY02353.1 - 0.015 14.0 1.5 0.11 11.2 0.5 2.4 2 0 0 2 2 2 0 HI0933-like protein Pet127 PF08634.10 KFY02354.1 - 1.7e-116 388.4 0.1 2.6e-116 387.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 STAT1_TAZ2bind PF12162.8 KFY02355.1 - 1.1 8.9 3.5 2.1 8.0 3.5 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Glyco_hydro_7 PF00840.20 KFY02356.1 - 5.5e-208 691.0 19.6 6.8e-208 690.7 19.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KFY02356.1 - 1.6e-12 47.1 13.3 1.6e-12 47.1 13.3 4.3 4 1 0 4 4 4 1 Fungal cellulose binding domain SLT PF01464.20 KFY02357.1 - 2e-06 27.4 0.0 5.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Bac_rhamnosid6H PF17389.2 KFY02358.1 - 1.4e-11 44.3 0.3 2.3e-11 43.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFY02358.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KFY02358.1 - 0.033 13.1 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KFY02358.1 - 0.038 12.8 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Trehalase DUF608 PF04685.13 KFY02358.1 - 0.14 11.3 0.8 0.23 10.6 0.8 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region LtrA PF06772.11 KFY02359.1 - 1.1e-33 116.9 27.1 1.4e-33 116.6 27.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Vpu PF00558.19 KFY02359.1 - 0.36 10.6 2.6 5.2 6.9 0.9 2.9 2 0 0 2 2 2 0 Vpu protein DKCLD PF08068.12 KFY02361.1 - 3.7e-33 113.4 0.3 1e-31 108.8 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KFY02361.1 - 2.3e-23 83.2 0.2 2.8e-20 73.2 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFY02361.1 - 1.6e-22 79.4 1.2 3e-22 78.5 1.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KFY02361.1 - 9.8e-22 76.7 1.3 2e-21 75.7 1.3 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFY02361.1 - 0.0018 18.5 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain AP3D1 PF06375.11 KFY02361.1 - 0.45 10.7 18.4 0.76 10.0 18.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4407 PF14362.6 KFY02361.1 - 8.6 5.6 5.7 15 4.8 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_5 PF13546.6 KFY02363.1 - 0.061 12.6 0.6 0.13 11.6 0.6 1.5 1 1 0 1 1 1 0 DDE superfamily endonuclease RF-1 PF00472.20 KFY02364.1 - 0.042 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 RF-1 domain NDT80_PhoG PF05224.12 KFY02365.1 - 2.1e-42 145.5 0.0 2.9e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Myb_DNA-binding PF00249.31 KFY02365.1 - 0.049 13.8 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain TOH_N PF12549.8 KFY02376.1 - 0.35 10.8 5.9 7.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal Pkinase PF00069.25 KFY02382.1 - 1.1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02382.1 - 0.022 14.1 0.1 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3723 PF12520.8 KFY02388.1 - 4.3e-105 352.3 0.4 4.3e-105 352.3 0.4 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) BTB PF00651.31 KFY02388.1 - 5.6e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1640 PF07798.11 KFY02388.1 - 0.077 13.0 3.6 0.22 11.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Na_H_Exchanger PF00999.21 KFY02390.1 - 2.9e-26 92.2 41.6 2.6e-21 75.9 25.5 3.3 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family PetM PF08041.11 KFY02390.1 - 2 8.0 5.0 3 7.5 0.3 2.9 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 bZIP_1 PF00170.21 KFY02394.1 - 0.29 11.3 1.2 0.45 10.7 1.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor Dynamin_M PF01031.20 KFY02395.1 - 3.2e-47 161.1 0.1 6.4e-47 160.1 0.1 1.5 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFY02395.1 - 1.4e-26 93.6 0.0 3.5e-26 92.2 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFY02395.1 - 1.5e-05 25.1 0.2 0.00038 20.5 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY02395.1 - 0.011 15.3 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 KFY02395.1 - 0.058 13.6 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KFY02395.1 - 0.088 12.6 0.0 0.27 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GED PF02212.18 KFY02395.1 - 0.089 13.0 0.0 0.31 11.2 0.0 2.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain OTT_1508_deam PF14441.6 KFY02396.1 - 1.9e-14 53.4 0.1 9.5e-14 51.2 0.0 2.2 2 0 0 2 2 2 1 OTT_1508-like deaminase Phi29_Phage_SSB PF17427.2 KFY02396.1 - 0.088 13.0 0.5 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Phage Single-stranded DNA-binding protein Fungal_lectin_2 PF18647.1 KFY02397.1 - 6e-36 123.0 0.5 1e-35 122.2 0.5 1.4 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Ribonucleas_3_3 PF14622.6 KFY02397.1 - 4.9e-05 23.5 0.0 8.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFY02397.1 - 0.00028 21.5 0.0 0.00092 19.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Dynamin_N PF00350.23 KFY02398.1 - 5.4e-28 98.2 0.0 1.4e-27 96.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFY02398.1 - 5.2e-24 84.9 1.8 1.6e-23 83.4 0.7 2.2 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KFY02398.1 - 6.4e-05 23.0 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase UDPGT PF00201.18 KFY02398.1 - 0.061 12.1 2.2 0.089 11.6 2.2 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF4793 PF16041.5 KFY02398.1 - 0.093 12.9 0.6 0.2 11.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4793) TAF PF02969.17 KFY02398.1 - 0.095 12.9 0.6 7.6 6.8 0.2 2.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) DUF2398 PF09661.10 KFY02399.1 - 0.028 13.7 0.7 0.042 13.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) Tropomyosin PF00261.20 KFY02399.1 - 0.091 12.1 16.1 0.18 11.1 10.9 2.2 2 0 0 2 2 2 0 Tropomyosin DUF29 PF01724.16 KFY02399.1 - 2.9 8.1 11.0 0.47 10.7 3.9 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF29 DUF2175 PF09943.9 KFY02399.1 - 4.8 7.5 8.3 0.22 11.9 0.9 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) HSP70 PF00012.20 KFY02400.1 - 5e-08 31.6 0.0 1.1e-05 23.9 0.1 2.5 2 1 0 2 2 2 2 Hsp70 protein B9-C2 PF07162.11 KFY02400.1 - 0.087 13.0 0.1 0.33 11.1 0.0 1.9 2 0 0 2 2 2 0 Ciliary basal body-associated, B9 protein SesA PF17107.5 KFY02402.1 - 3.1e-05 24.1 0.4 0.00013 22.1 0.1 1.9 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KFY02402.1 - 4.3 7.6 15.7 7.8 6.7 8.1 2.4 1 1 1 2 2 2 0 Sigma domain on NACHT-NTPases PHM7_ext PF12621.8 KFY02403.1 - 7e-12 45.4 0.0 9.4e-12 45.0 0.0 1.3 1 1 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Ank_2 PF12796.7 KFY02415.1 - 1.2e-65 218.1 23.2 5.4e-11 42.9 0.4 10.5 4 2 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02415.1 - 1e-57 191.8 22.3 6.4e-07 29.8 0.1 16.8 4 4 14 19 19 19 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY02415.1 - 3.6e-39 128.3 24.1 0.0022 18.3 0.0 20.0 20 0 0 20 20 20 7 Ankyrin repeat Ank PF00023.30 KFY02415.1 - 2.2e-38 129.0 50.0 0.0068 16.8 0.1 20.0 20 0 0 20 20 20 13 Ankyrin repeat Ank_5 PF13857.6 KFY02415.1 - 2.8e-25 88.0 25.6 4.1e-05 23.8 0.1 12.0 9 2 3 13 13 13 7 Ankyrin repeats (many copies) NACHT PF05729.12 KFY02415.1 - 1.6e-11 44.4 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFY02415.1 - 9.2e-05 22.7 0.0 0.00026 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY02415.1 - 9.9e-05 22.8 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KFY02415.1 - 0.0017 17.6 1.5 1.4 8.0 0.0 3.2 2 1 1 3 3 3 1 KAP family P-loop domain Helo_like_N PF17111.5 KFY02415.1 - 0.0094 15.3 1.0 0.12 11.8 0.2 2.7 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins RNA_helicase PF00910.22 KFY02415.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KFY02415.1 - 0.027 13.7 0.0 0.065 12.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KFY02415.1 - 0.049 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFY02415.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HdeA PF06411.11 KFY02416.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Sugar_tr PF00083.24 KFY02417.1 - 2e-77 261.0 24.4 2.4e-77 260.7 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02417.1 - 1.1e-22 80.4 44.5 7.6e-20 71.1 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.15 KFY02417.1 - 0.023 15.5 1.3 1.1 10.1 0.0 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 MFS_2 PF13347.6 KFY02417.1 - 0.064 11.8 27.1 0.036 12.6 2.5 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein Pam17 PF08566.10 KFY02417.1 - 0.26 11.1 2.2 0.19 11.6 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF5542 PF17696.1 KFY02417.1 - 1.3 9.2 3.3 3 8.0 3.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Glyco_hydro_1 PF00232.18 KFY02418.1 - 2.8e-150 500.7 0.6 3.4e-150 500.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.18 KFY02419.1 - 6.8e-12 45.0 0.2 1.6e-11 43.8 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02419.1 - 3.4e-11 43.1 4.8 5.9e-11 42.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2656 PF10847.8 KFY02419.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) DLH PF01738.18 KFY02420.1 - 6.2e-28 97.8 0.0 1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 KFY02421.1 - 2.3e-07 30.1 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 KFY02422.1 - 5.1e-08 32.9 0.1 3.4e-06 26.9 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY02422.1 - 3.8e-07 29.6 0.0 7.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY02422.1 - 2.4e-06 28.3 0.1 3.9e-06 27.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY02423.1 - 6.6e-20 71.8 0.2 7.7e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02423.1 - 3e-10 41.1 2.0 3.9e-10 40.7 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY02423.1 - 0.00048 19.5 0.0 0.00081 18.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 HA2 PF04408.23 KFY02424.1 - 6.6 7.1 6.5 0.65 10.3 1.3 2.0 2 0 0 2 2 2 0 Helicase associated domain (HA2) Ank_2 PF12796.7 KFY02425.1 - 5.8e-135 440.2 35.6 7.5e-19 68.1 0.4 11.0 2 1 9 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02425.1 - 8.3e-102 332.4 20.1 1.1e-11 45.0 0.1 16.2 6 3 11 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 KFY02425.1 - 1.4e-89 291.0 14.8 2.5e-05 24.5 0.1 19.3 20 0 0 20 20 20 16 Ankyrin repeat Ank_3 PF13606.6 KFY02425.1 - 4.7e-81 257.0 9.5 3.5e-05 23.9 0.0 20.0 20 0 0 20 20 20 16 Ankyrin repeat Ank_5 PF13857.6 KFY02425.1 - 7.7e-66 217.3 27.8 6.5e-11 42.3 0.3 12.4 7 3 5 12 12 12 10 Ankyrin repeats (many copies) Goodbye PF17109.5 KFY02425.1 - 1.9e-14 54.2 0.0 1.4e-13 51.3 0.0 2.7 1 1 0 1 1 1 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KFY02425.1 - 0.0024 18.2 0.0 0.0074 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Integrase_H2C2 PF17921.1 KFY02426.1 - 5.7e-06 26.3 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Pkinase_fungal PF17667.1 KFY02428.1 - 6.8e-50 170.0 0.0 9.2e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFY02428.1 - 3e-10 39.9 0.0 3.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02428.1 - 7.3e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFY02428.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFY02428.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF4886 PF16227.5 KFY02437.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Zip PF02535.22 KFY02452.1 - 1.1e-17 64.3 0.0 1.3e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FAM70 PF14967.6 KFY02459.1 - 0.81 9.1 9.8 1.3 8.5 9.8 1.3 1 0 0 1 1 1 0 FAM70 protein OmpH PF03938.14 KFY02460.1 - 0.025 14.9 3.4 0.037 14.4 3.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 KFY02460.1 - 0.044 13.4 2.2 0.059 12.9 2.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 KFY02460.1 - 0.34 11.4 4.8 0.7 10.4 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 KxDL PF10241.9 KFY02460.1 - 0.36 11.1 3.7 0.48 10.7 2.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Pox_A_type_inc PF04508.12 KFY02460.1 - 7.8 6.5 12.3 2.6 8.0 1.1 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat F-box PF00646.33 KFY02461.1 - 0.11 12.4 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 F-box domain PH_18 PF18469.1 KFY02464.1 - 0.077 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SSURE PF11966.8 KFY02464.1 - 0.13 12.0 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 Fibronectin-binding repeat DDE_Tnp_4 PF13359.6 KFY02465.1 - 0.17 11.5 0.3 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease Syntaxin-6_N PF09177.11 KFY02465.1 - 0.93 10.1 20.0 1.7 9.3 3.9 4.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Lipoprotein_20 PF13942.6 KFY02465.1 - 2.8 7.9 10.4 0.25 11.2 3.6 2.6 3 0 0 3 3 3 0 YfhG lipoprotein CCDC-167 PF15188.6 KFY02465.1 - 6.7 7.1 14.0 0.097 13.0 1.8 3.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3798 PF12683.7 KFY02466.1 - 0.0051 16.3 3.1 0.25 10.7 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3798) SdpA PF17418.2 KFY02466.1 - 0.051 13.4 3.0 0.81 9.5 0.3 2.4 1 1 1 2 2 2 0 Sporulation delaying protein SdpA PPO1_KFDV PF12143.8 KFY02466.1 - 0.28 11.3 5.5 1.4 9.0 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF_B2219) TMF_TATA_bd PF12325.8 KFY02466.1 - 0.51 10.6 15.3 0.086 13.1 8.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF728 PF05304.12 KFY02466.1 - 0.6 10.0 2.7 2.6 7.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF728) Tap-RNA_bind PF09162.10 KFY02466.1 - 0.62 9.9 2.2 3.1 7.7 0.1 2.8 3 1 1 4 4 4 0 Tap, RNA-binding PIN_6 PF17146.4 KFY02466.1 - 0.66 10.5 3.2 2.3 8.8 0.6 2.3 2 0 0 2 2 2 0 PIN domain of ribonuclease DUF3723 PF12520.8 KFY02467.1 - 1.9e-95 320.5 0.2 4.5e-95 319.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) BRE1 PF08647.11 KFY02467.1 - 0.0015 18.6 9.4 0.0015 18.6 9.4 6.4 4 1 1 5 5 5 1 BRE1 E3 ubiquitin ligase L31 PF09784.9 KFY02467.1 - 1.7 9.1 5.5 2.8 8.4 1.1 3.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 DUF3723 PF12520.8 KFY02484.1 - 2.1e-73 247.8 1.2 5.4e-30 104.5 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) IKBKB_SDD PF18397.1 KFY02484.1 - 0.018 14.4 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Ank_2 PF12796.7 KFY02487.1 - 7.8e-33 112.9 0.1 5.3e-10 39.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02487.1 - 6.5e-24 84.0 1.0 6.8e-09 36.1 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY02487.1 - 6.3e-22 77.0 1.1 0.0011 19.3 0.0 6.1 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFY02487.1 - 9.4e-21 71.7 0.0 0.0056 17.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KFY02487.1 - 1.6e-20 72.9 1.5 1.6e-05 25.1 0.1 6.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 KFY02487.1 - 0.00077 19.8 6.6 0.0013 19.0 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFY02487.1 - 0.14 12.0 3.3 0.26 11.2 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY02487.1 - 0.26 11.1 5.8 0.46 10.4 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFY02487.1 - 0.52 10.1 2.4 0.99 9.2 2.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger MFS_1 PF07690.16 KFY02503.1 - 2.4e-18 66.2 43.9 6.8e-10 38.4 28.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Steroid_dh PF02544.16 KFY02503.1 - 0.0067 16.4 0.1 0.02 14.9 0.1 1.8 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_31 PF13847.6 KFY02504.1 - 2.8e-15 56.4 0.0 4.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02504.1 - 7.2e-14 52.2 0.0 1.6e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02504.1 - 3.5e-12 46.9 0.3 8.1e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02504.1 - 1.9e-07 30.7 0.0 3.9e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY02504.1 - 1.1e-05 26.1 0.0 2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFY02504.1 - 0.00073 19.5 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KFY02504.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFY02504.1 - 0.0021 17.4 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain ZapB PF06005.12 KFY02506.1 - 0.0015 18.9 0.5 0.0028 18.1 0.5 1.4 1 0 0 1 1 1 1 Cell division protein ZapB AKNA PF12443.8 KFY02506.1 - 0.017 15.8 1.3 0.041 14.5 1.3 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor CC2-LZ PF16516.5 KFY02506.1 - 0.019 15.3 1.4 0.034 14.5 1.4 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator bZIP_1 PF00170.21 KFY02506.1 - 0.02 15.0 8.2 0.035 14.2 8.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor PspA_IM30 PF04012.12 KFY02506.1 - 0.024 14.2 2.8 0.038 13.6 2.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family Csm1_N PF18504.1 KFY02506.1 - 0.043 14.1 4.9 0.087 13.2 4.9 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain Spc7 PF08317.11 KFY02506.1 - 0.044 12.7 3.4 0.056 12.3 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KFY02506.1 - 0.055 13.9 0.4 0.1 13.0 0.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 KFY02506.1 - 0.061 13.4 10.0 0.1 12.7 10.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Prefoldin_2 PF01920.20 KFY02506.1 - 0.063 13.2 1.5 0.1 12.6 1.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit SlyX PF04102.12 KFY02506.1 - 0.065 13.9 1.0 0.12 13.0 1.0 1.4 1 0 0 1 1 1 0 SlyX Jnk-SapK_ap_N PF09744.9 KFY02506.1 - 0.083 13.1 5.3 0.13 12.5 5.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HR1 PF02185.16 KFY02506.1 - 0.12 12.5 8.8 0.35 11.0 8.8 1.8 1 1 0 1 1 1 0 Hr1 repeat EzrA PF06160.12 KFY02506.1 - 0.18 9.9 1.9 0.24 9.5 1.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4140 PF13600.6 KFY02506.1 - 0.35 11.3 4.8 0.6 10.6 4.8 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 KFY02506.1 - 0.56 10.5 1.4 0.97 9.7 1.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Med7 PF05983.11 KFY02506.1 - 2.4 8.2 5.0 2.5 8.2 3.5 1.8 2 0 0 2 2 2 0 MED7 protein NAD_binding_6 PF08030.12 KFY02510.1 - 3e-17 63.2 0.0 5.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFY02510.1 - 7.4e-16 58.2 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KFY02510.1 - 1.7e-14 54.0 5.8 4.6e-14 52.6 5.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 KFY02510.1 - 0.0026 17.2 1.8 0.0056 16.1 1.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFY02510.1 - 0.021 15.2 0.5 0.048 14.1 0.5 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFY02510.1 - 0.034 14.1 0.5 0.14 12.2 0.8 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 KFY02510.1 - 0.041 13.4 0.6 0.09 12.3 0.6 1.5 1 0 0 1 1 1 0 EF hand zinc_ribbon_15 PF17032.5 KFY02511.1 - 0.034 14.9 5.2 0.045 14.5 5.2 1.4 1 1 0 1 1 1 0 zinc-ribbon family TMEM51 PF15345.6 KFY02511.1 - 0.072 12.9 0.5 0.08 12.8 0.5 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 DASH_Spc34 PF08657.10 KFY02511.1 - 0.34 10.7 6.1 0.41 10.4 6.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 zinc_ribbon_2 PF13240.6 KFY02511.1 - 2.2 8.1 12.8 9.8 6.0 12.8 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFY02511.1 - 4.5 6.8 10.7 9.9 5.7 10.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain MARVEL PF01284.23 KFY02512.1 - 1.1e-09 38.5 14.3 1.8e-09 37.8 14.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DZR PF12773.7 KFY02512.1 - 0.0015 18.5 0.9 0.0024 17.8 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFY02512.1 - 0.0066 16.1 3.2 0.013 15.2 3.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain ABC2_membrane_5 PF13346.6 KFY02512.1 - 0.012 15.1 3.6 0.012 15.1 3.6 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein zf-ribbon_3 PF13248.6 KFY02512.1 - 0.043 13.2 1.6 0.087 12.3 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFY02512.1 - 0.044 14.5 0.5 0.069 13.9 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon family Nudix_N_2 PF14803.6 KFY02512.1 - 3.9 7.5 5.2 8.8 6.3 0.5 2.3 2 0 0 2 2 2 0 Nudix N-terminal Glyco_hydro_31 PF01055.26 KFY02513.1 - 7.1e-105 351.7 0.0 9.5e-105 351.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFY02513.1 - 1.8e-15 57.0 0.1 5.4e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like TRAP_alpha PF03896.16 KFY02514.1 - 2.2e-08 33.7 0.5 1.5e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit F-box PF00646.33 KFY02515.1 - 0.28 11.1 4.1 0.16 11.9 0.6 2.5 3 0 0 3 3 3 0 F-box domain CCDC144C PF14915.6 KFY02516.1 - 0.003 16.7 0.7 0.0055 15.9 0.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF2570 PF10828.8 KFY02516.1 - 0.0037 17.1 3.9 0.0087 15.9 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) TMF_TATA_bd PF12325.8 KFY02516.1 - 0.0048 17.1 1.8 0.016 15.4 1.8 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Prefoldin_2 PF01920.20 KFY02516.1 - 0.0072 16.3 0.8 0.015 15.2 0.8 1.5 1 0 0 1 1 1 1 Prefoldin subunit DUF4164 PF13747.6 KFY02516.1 - 0.016 15.5 0.9 0.056 13.7 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Lipoprotein_20 PF13942.6 KFY02516.1 - 0.032 14.1 0.6 0.054 13.4 0.6 1.3 1 0 0 1 1 1 0 YfhG lipoprotein DUF5082 PF16888.5 KFY02516.1 - 0.032 14.5 1.5 0.032 14.5 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Transcrip_act PF04949.13 KFY02516.1 - 0.034 14.0 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator Tup_N PF08581.10 KFY02516.1 - 0.086 13.2 0.3 0.22 11.8 0.3 1.7 1 0 0 1 1 1 0 Tup N-terminal Prominin PF05478.11 KFY02516.1 - 0.087 10.8 0.4 0.15 10.0 0.4 1.3 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 KFY02516.1 - 0.2 11.0 2.7 0.38 10.1 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KFY02516.1 - 0.26 11.6 5.9 0.29 11.4 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2203 PF09969.9 KFY02516.1 - 0.46 11.2 1.6 1.8 9.3 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FeoC PF09012.10 KFY02517.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator ELO PF01151.18 KFY02527.1 - 2.6e-07 30.5 2.2 2.6e-07 30.5 2.2 1.9 1 1 1 2 2 2 1 GNS1/SUR4 family Ribosomal_S12 PF17487.2 KFY02527.1 - 0.028 15.2 1.3 0.47 11.2 1.1 2.7 2 1 0 2 2 2 0 Ribosomal protein S12 Methyltransf_25 PF13649.6 KFY02528.1 - 3.7e-11 43.6 0.0 7.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02528.1 - 1.6e-10 41.5 0.0 2.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02528.1 - 3.5e-09 36.3 0.0 6.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFY02528.1 - 3.2e-07 30.3 0.0 5.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY02528.1 - 0.00034 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY02528.1 - 0.0088 16.8 0.0 0.022 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF2169 PF09937.9 KFY02528.1 - 0.095 12.1 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) BLOC1S3 PF15753.5 KFY02544.1 - 0.01 16.0 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 UPF0182 PF03699.13 KFY02544.1 - 0.1 10.7 0.5 0.11 10.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Hph PF13694.6 KFY02545.1 - 0.0097 16.2 0.8 0.018 15.4 0.8 1.4 1 0 0 1 1 1 1 Sec63/Sec62 complex-interacting family Retrotrans_gag PF03732.17 KFY02545.1 - 0.011 16.0 2.4 0.017 15.4 0.1 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein bZIP_1 PF00170.21 KFY02545.1 - 0.1 12.7 11.7 0.1 12.7 9.9 1.9 2 0 0 2 2 2 0 bZIP transcription factor DP PF08781.10 KFY02545.1 - 0.21 11.5 8.5 0.086 12.7 4.4 2.1 2 0 0 2 2 2 0 Transcription factor DP DUF1003 PF06210.11 KFY02545.1 - 1.7 8.8 5.7 0.31 11.1 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Ank_2 PF12796.7 KFY02547.1 - 9.4e-15 55.0 0.0 1.8e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY02547.1 - 3.2e-12 45.5 0.0 0.0003 21.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFY02547.1 - 4.3e-10 39.6 0.0 0.0025 18.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFY02547.1 - 8.9e-07 29.1 0.0 0.0048 17.2 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFY02547.1 - 1.3e-06 28.8 0.0 0.0018 18.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) F-box PF00646.33 KFY02547.1 - 0.064 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 F-box domain Milton PF12448.8 KFY02547.1 - 2.6 8.1 7.0 9.2 6.3 1.9 2.2 2 0 0 2 2 2 0 Kinesin associated protein HC2 PF07382.11 KFY02548.1 - 4.3e-06 26.9 25.0 4.3e-06 26.9 25.0 2.2 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 Cu-oxidase_3 PF07732.15 KFY02549.1 - 3.2e-19 69.1 0.1 4.6e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 KFY02549.1 - 0.00079 19.6 0.0 0.0018 18.4 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY02549.1 - 0.081 12.7 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Multicopper oxidase PGA_cap PF09587.10 KFY02578.1 - 0.12 11.8 0.4 0.17 11.3 0.4 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap RTA1 PF04479.13 KFY02579.1 - 4.9e-42 143.9 2.6 1e-37 129.8 0.8 2.7 1 1 1 2 2 2 2 RTA1 like protein adh_short PF00106.25 KFY02579.1 - 6.7e-38 130.1 0.0 1.1e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02579.1 - 1.9e-22 79.9 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.8 KFY02579.1 - 9e-08 31.3 6.2 2.4e-07 29.9 0.2 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain KR PF08659.10 KFY02579.1 - 3.7e-06 27.0 0.0 9.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFY02579.1 - 0.00053 19.9 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFY02579.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFY02579.1 - 0.033 13.6 0.0 0.087 12.3 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HisKA_7TM PF16927.5 KFY02580.1 - 0.47 10.5 16.0 0.69 9.9 15.7 1.4 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase Rhomboid PF01694.22 KFY02580.1 - 0.54 10.2 11.0 0.088 12.8 6.2 2.1 1 1 1 2 2 2 0 Rhomboid family Cu-oxidase_2 PF07731.14 KFY02596.1 - 2.3e-40 137.5 1.5 3.2e-36 124.1 0.4 3.4 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFY02596.1 - 4.7e-19 68.6 0.1 2.9e-18 66.0 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFY02596.1 - 9.5e-18 64.8 0.0 6.1e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase PEP_mutase PF13714.6 KFY02597.1 - 5.8e-42 143.8 0.2 8.8e-42 143.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFY02597.1 - 1.6e-22 79.7 0.3 2.3e-22 79.2 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family HMA PF00403.26 KFY02598.1 - 1.6e-12 47.7 2.3 1.9e-12 47.4 2.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KFY02599.1 - 1.4e-43 148.5 0.1 1.4e-43 148.5 0.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFY02599.1 - 2.1e-41 142.5 0.1 4e-41 141.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFY02599.1 - 1.5e-31 108.6 1.0 4.1e-13 49.6 0.6 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFY02599.1 - 5.5e-05 23.0 0.4 0.0014 18.4 0.3 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFY02599.1 - 0.00092 19.7 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_3 PF08777.11 KFY02599.1 - 0.096 12.7 0.0 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif DUF4342 PF14242.6 KFY02599.1 - 0.12 12.4 0.3 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF2162 PF09930.9 KFY02599.1 - 4.3 6.7 8.4 0.24 10.8 1.6 2.3 2 0 0 2 2 2 0 Predicted transporter (DUF2162) Bul1_C PF04426.12 KFY02610.1 - 0.014 14.8 0.1 0.034 13.6 0.1 1.6 1 0 0 1 1 1 0 Bul1 C terminus Sugar_tr PF00083.24 KFY02611.1 - 3.1e-44 151.6 22.8 4.8e-44 151.0 22.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02611.1 - 1.9e-19 69.8 51.3 1.5e-18 66.9 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.26 KFY02612.1 - 5.5e-12 45.5 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DTHCT PF08070.11 KFY02612.1 - 1 10.2 6.4 2.9 8.7 6.4 1.8 1 1 0 1 1 1 0 DTHCT (NUC029) region Tropomyosin_1 PF12718.7 KFY02621.1 - 0.12 12.5 14.5 0.2 11.8 6.8 2.2 1 1 1 2 2 2 0 Tropomyosin like TFIIA PF03153.13 KFY02622.1 - 0.0064 16.5 0.8 0.0064 16.5 0.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ABC_tran_2 PF16949.5 KFY02622.1 - 0.038 12.8 0.1 0.048 12.5 0.1 1.0 1 0 0 1 1 1 0 Putative ATP-binding cassette Astro_capsid_p PF12226.8 KFY02622.1 - 0.85 8.7 8.9 1.1 8.3 8.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Phage_holin_2_3 PF16080.5 KFY02623.1 - 0.043 13.6 0.9 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Cyt_bd_oxida_II PF02322.15 KFY02623.1 - 0.062 12.7 6.4 0.085 12.2 6.4 1.3 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II F-box PF00646.33 KFY02624.1 - 0.15 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain Imm58 PF15581.6 KFY02624.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 58 Glyco_hydro_18 PF00704.28 KFY02625.1 - 1.1e-74 252.0 0.7 1.4e-74 251.6 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4860 PF16152.5 KFY02626.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4860) HlyIII PF03006.20 KFY02654.1 - 5e-13 49.3 0.4 6.3e-13 49.0 0.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Tropomyosin_1 PF12718.7 KFY02655.1 - 0.35 11.0 13.8 0.13 12.4 5.8 2.1 1 1 1 2 2 2 0 Tropomyosin like Hydrolase_4 PF12146.8 KFY02657.1 - 0.17 11.2 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Phage_holin_2_3 PF16080.5 KFY02658.1 - 0.048 13.4 0.7 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Glyco_hydro_18 PF00704.28 KFY02659.1 - 1.4e-76 258.3 1.3 1.8e-76 257.9 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MscS_TM PF12794.7 KFY02663.1 - 0.66 8.8 2.8 0.83 8.4 2.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3886 PF13025.6 KFY02663.1 - 0.9 9.8 8.4 1.4 9.1 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Aminotran_3 PF00202.21 KFY02664.1 - 1.3e-65 221.7 0.0 9.4e-65 218.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III TFIIA PF03153.13 KFY02666.1 - 1.3 8.9 15.1 0.11 12.5 8.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 KFY02667.1 - 2.9e-14 53.2 0.0 5.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02667.1 - 8.3e-08 32.8 0.0 3e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY02667.1 - 9.7e-08 31.9 0.0 5.5e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02667.1 - 6.3e-07 30.0 0.0 2.7e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY02667.1 - 0.00056 20.6 0.0 0.002 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02667.1 - 0.023 14.0 0.0 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DP PF08781.10 KFY02667.1 - 0.031 14.2 5.4 0.065 13.1 5.4 1.5 1 0 0 1 1 1 0 Transcription factor DP Methyltransf_8 PF05148.15 KFY02667.1 - 0.13 12.1 0.1 6.8 6.5 0.0 2.6 2 1 0 2 2 2 0 Hypothetical methyltransferase APC_u15 PF16636.5 KFY02689.1 - 0.26 11.7 5.9 0.67 10.4 5.9 1.7 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 DUF4407 PF14362.6 KFY02689.1 - 0.44 9.9 3.2 0.62 9.4 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Casc1_N PF15927.5 KFY02689.1 - 3.4 7.3 21.7 5.9 6.5 21.7 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CYYR1 PF10873.8 KFY02691.1 - 0.95 9.9 4.2 2.4 8.6 4.2 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Gly_transf_sug PF04488.15 KFY02714.1 - 2e-09 38.0 0.0 4.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KFY02714.1 - 6e-07 29.1 0.0 8.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein HNOBA PF07701.14 KFY02714.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated Gly_transf_sug PF04488.15 KFY02715.1 - 2.8e-10 40.7 0.0 9.3e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KFY02715.1 - 9e-08 31.8 0.1 1.3e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein ALO PF04030.14 KFY02716.1 - 4.2e-85 285.7 1.4 7.9e-85 284.8 1.4 1.5 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KFY02716.1 - 4.4e-27 94.5 0.0 7.9e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HC2 PF07382.11 KFY02716.1 - 7.7e-15 55.5 371.3 6.4e-06 26.4 90.3 6.2 2 1 5 7 7 7 6 Histone H1-like nucleoprotein HC2 Haem_degrading PF03928.14 KFY02717.1 - 2e-28 98.9 0.0 3e-28 98.2 0.0 1.3 1 1 0 1 1 1 1 Haem-degrading HEAT PF02985.22 KFY02718.1 - 2.1e-13 49.2 16.0 0.00055 20.0 0.2 9.0 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 KFY02718.1 - 1.1e-09 38.5 0.8 8.7e-07 29.3 0.0 6.9 6 2 2 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KFY02718.1 - 1.2e-07 32.0 13.3 0.0014 18.9 0.2 6.9 3 2 5 8 8 8 4 HEAT repeats DRIM PF07539.12 KFY02718.1 - 8.8e-07 27.6 4.6 0.36 9.1 0.0 5.7 4 3 2 6 6 6 3 Down-regulated in metastasis CLASP_N PF12348.8 KFY02718.1 - 1.5e-06 27.9 2.3 0.11 12.1 0.0 5.6 4 1 1 6 6 6 1 CLASP N terminal IBN_N PF03810.19 KFY02718.1 - 1.8e-06 27.8 1.7 0.00067 19.5 0.3 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KFY02718.1 - 0.0001 22.2 5.3 0.19 11.8 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KFY02718.1 - 0.0058 17.2 1.0 20 6.2 0.0 4.7 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat MMS19_N PF14500.6 KFY02718.1 - 0.0075 15.9 0.5 6.5 6.2 0.0 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.8 KFY02718.1 - 0.018 14.9 3.2 12 5.8 0.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) Sec7_N PF12783.7 KFY02718.1 - 0.14 12.0 0.2 32 4.4 0.0 3.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HMGL-like PF00682.19 KFY02719.1 - 4.2e-79 265.8 0.0 5.9e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KFY02719.1 - 1.9e-24 86.1 0.0 3.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Zn_clus PF00172.18 KFY02720.1 - 0.0086 16.2 9.0 0.017 15.2 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KFY02721.1 - 2e-19 69.0 0.2 2.5e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KFY02721.1 - 0.00067 20.2 14.1 0.00096 19.7 14.1 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 TYW3 PF02676.14 KFY02722.1 - 2e-73 246.3 0.0 2.5e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 ARPC4 PF05856.12 KFY02724.1 - 4.1e-61 205.4 2.6 4.8e-61 205.2 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KFY02725.1 - 3.8e-50 170.8 0.0 4.8e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFY02725.1 - 1.7e-13 50.9 1.8 6e-08 32.6 0.5 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFY02725.1 - 3.9e-11 42.5 0.0 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Coagulase PF08764.10 KFY02725.1 - 0.02 15.1 0.9 0.035 14.3 0.9 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Terminase_3C PF17288.2 KFY02725.1 - 0.084 13.3 0.2 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 Terminase RNAseH like domain GST_N_4 PF17172.4 KFY02728.1 - 0.12 13.1 0.0 0.55 11.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain DUF2514 PF10721.9 KFY02731.1 - 0.029 14.4 5.0 0.052 13.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Tae4 PF14113.6 KFY02731.1 - 0.14 12.4 0.5 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 U79_P34 PF03064.16 KFY02731.1 - 3.6 6.9 9.6 7.1 5.9 9.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Helicase_C PF00271.31 KFY02744.1 - 1.8e-13 50.8 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain bZIP_1 PF00170.21 KFY02759.1 - 0.025 14.7 0.3 0.049 13.7 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Ferric_reduct PF01794.19 KFY02760.1 - 1.8e-12 47.4 8.6 3.6e-12 46.5 7.2 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY02760.1 - 4.3e-06 26.8 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Cation_ATPase_C PF00689.21 KFY02780.1 - 8.7e-12 45.1 0.2 1.2e-11 44.7 0.2 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_efflux PF01545.21 KFY02782.1 - 4.5e-33 114.7 0.7 1.2e-30 106.7 0.7 2.1 1 1 0 1 1 1 1 Cation efflux family DUF3483 PF11982.8 KFY02782.1 - 0.026 14.2 0.2 1.9 8.0 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3483) Abhydrolase_3 PF07859.13 KFY02796.1 - 3.4e-41 141.4 0.0 4.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFY02796.1 - 1.5e-08 34.0 0.4 4.6e-08 32.4 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KFY02796.1 - 0.0028 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KFY02796.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFY02796.1 - 0.19 10.7 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase E1-E2_ATPase PF00122.20 KFY02797.1 - 5.7e-17 61.8 0.3 7.9e-17 61.4 0.3 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFY02797.1 - 3.4e-12 47.1 0.1 4.4e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY02798.1 - 0.00018 21.8 0.0 0.00027 21.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFY02798.1 - 0.00021 21.1 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2148 PF09918.9 KFY02798.1 - 0.015 15.3 0.8 0.031 14.3 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Caveolin PF01146.17 KFY02798.1 - 0.021 14.8 0.2 0.025 14.6 0.2 1.1 1 0 0 1 1 1 0 Caveolin Fis1_TPR_N PF14852.6 KFY02798.1 - 0.042 13.5 0.2 0.085 12.5 0.2 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Cu-oxidase_3 PF07732.15 KFY02799.1 - 2.4e-09 37.2 4.1 4e-09 36.5 0.3 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY02799.1 - 4.2e-07 29.8 3.7 0.00023 20.9 0.2 2.2 1 1 1 2 2 2 2 Multicopper oxidase Ctr PF04145.15 KFY02799.1 - 9.5e-06 26.3 0.4 1.4e-05 25.7 0.4 1.5 1 0 0 1 1 1 1 Ctr copper transporter family FSH1 PF03959.13 KFY02809.1 - 3.1e-27 95.6 0.0 3.1e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 KFY02809.1 - 0.016 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 KFY02809.1 - 0.14 12.7 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family BTB PF00651.31 KFY02810.1 - 0.00067 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1415 PF07209.12 KFY02810.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) APH PF01636.23 KFY02815.1 - 9.4e-14 51.9 0.1 2.8e-13 50.3 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY02815.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFY02815.1 - 0.0054 16.3 0.1 0.37 10.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KFY02815.1 - 0.025 13.9 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 KFY02815.1 - 0.25 10.1 0.0 0.81 8.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4567 PF15131.6 KFY02817.1 - 0.13 12.3 0.4 1.5 8.9 0.0 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4567) HrpB1_HrpK PF09613.10 KFY02818.1 - 0.017 14.8 0.1 0.044 13.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) E1-E2_ATPase PF00122.20 KFY02820.1 - 1.5e-17 63.7 0.1 3.4e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFY02820.1 - 2.8e-11 42.9 0.1 7e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF5123 PF17161.4 KFY02820.1 - 1.4 10.0 4.4 0.72 10.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) Methyltransf_31 PF13847.6 KFY02829.1 - 5.9e-13 48.9 0.0 8.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02829.1 - 2.7e-11 44.0 0.0 5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02829.1 - 4.1e-11 43.4 0.0 7.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02829.1 - 6.4e-07 28.9 0.0 9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY02829.1 - 0.0005 20.8 0.0 0.00084 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFY02829.1 - 0.0028 17.6 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 KFY02829.1 - 0.0028 17.5 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFY02829.1 - 0.015 14.6 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Cupin_1 PF00190.22 KFY02836.1 - 1.9e-19 69.8 0.3 3.7e-19 68.8 0.3 1.4 1 0 0 1 1 1 1 Cupin Ank_2 PF12796.7 KFY02836.1 - 6e-11 42.8 0.0 1.2e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY02836.1 - 1.5e-06 28.0 0.1 0.043 14.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFY02836.1 - 1.7e-05 25.2 0.0 0.00088 19.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY02836.1 - 2.8e-05 24.4 0.0 0.11 13.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFY02836.1 - 4.1e-05 23.8 0.0 0.0054 17.0 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Cupin_2 PF07883.11 KFY02836.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain YfhO PF09586.10 KFY02837.1 - 0.32 9.2 1.5 0.44 8.7 1.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2207 PF09972.9 KFY02837.1 - 6.8 5.3 4.6 13 4.4 4.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Terpene_synth_C PF03936.16 KFY02838.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain AMP-binding PF00501.28 KFY02868.1 - 2.1e-05 23.3 0.0 3.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY02868.1 - 0.0077 17.2 0.0 0.013 16.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LTXXQ PF07813.12 KFY02869.1 - 0.027 15.2 0.1 0.044 14.5 0.1 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein DUF2673 PF10880.8 KFY02869.1 - 0.038 14.1 0.7 0.27 11.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Ldi PF18566.1 KFY02871.1 - 1.3e-133 445.4 0.0 1.6e-133 445.1 0.0 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Adipogenin PF15202.6 KFY02871.1 - 0.0059 16.6 0.5 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Adipogenin PGP_phosphatase PF09419.10 KFY02872.1 - 7e-49 165.7 0.0 1.2e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KFY02872.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like F-box-like PF12937.7 KFY02872.1 - 0.0057 16.5 0.8 0.058 13.3 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KFY02872.1 - 0.02 14.8 0.3 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 F-box-like domain LSM PF01423.22 KFY02873.1 - 1.8e-15 56.3 0.2 2.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFY02873.1 - 0.095 12.9 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain PhoLip_ATPase_C PF16212.5 KFY02874.1 - 1.7e-69 234.3 20.0 1.7e-69 234.3 20.0 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFY02874.1 - 5.6e-25 86.8 1.4 3.9e-23 80.9 0.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFY02874.1 - 1.2e-16 61.7 0.5 3.8e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY02874.1 - 1e-10 41.5 0.0 6.9e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFY02874.1 - 3.4e-08 33.2 0.2 1e-07 31.7 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFY02874.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MAP17 PF15807.5 KFY02874.1 - 0.018 15.2 0.3 0.018 15.2 0.3 2.9 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Myb_DNA-bind_6 PF13921.6 KFY02875.1 - 4.4e-12 46.1 0.1 1.2e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFY02875.1 - 4.8e-10 39.5 0.2 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF5053 PF16476.5 KFY02875.1 - 0.16 11.7 0.1 0.42 10.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) PRP8_domainIV PF12134.8 KFY02877.1 - 5e-127 422.2 1.7 5e-127 422.2 1.7 1.8 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFY02877.1 - 1.2e-57 194.4 2.1 2.2e-57 193.4 0.1 2.5 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PROCT PF08084.11 KFY02877.1 - 3.4e-48 162.6 0.2 1.7e-47 160.4 0.0 2.3 2 0 0 2 2 2 1 PROCT (NUC072) domain OCD_Mu_crystall PF02423.15 KFY02877.1 - 0.12 11.2 0.7 0.2 10.6 0.7 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.18 KFY02878.1 - 3.7e-44 148.9 2.7 4.8e-44 148.6 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KFY02878.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 KFY02878.1 - 0.65 10.0 4.2 4.7 7.2 0.1 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Alk_phosphatase PF00245.20 KFY02879.1 - 2.1e-105 353.1 0.0 2.6e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFY02879.1 - 8.5e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.9 KFY02879.1 - 0.0073 16.6 0.0 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF498 PF04430.14 KFY02880.1 - 3.1e-32 110.9 0.0 4.3e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pkinase_fungal PF17667.1 KFY02893.1 - 7.6e-06 25.0 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFY02893.1 - 1.9e-05 24.2 0.1 3.4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFY02893.1 - 4.6e-05 23.5 0.0 0.011 15.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFY02893.1 - 0.00013 21.4 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFY02893.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KFY02906.1 - 3.7e-06 26.5 0.0 0.11 11.9 0.0 2.7 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02906.1 - 1.4e-05 24.6 0.0 0.0045 16.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase COesterase PF00135.28 KFY02916.1 - 7.6e-85 285.7 0.0 1.5e-83 281.4 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Sec1 PF00995.23 KFY02916.1 - 1.7e-20 73.8 0.0 2.4e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Abhydrolase_3 PF07859.13 KFY02916.1 - 2.7e-06 27.4 0.1 9e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY02916.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RTA1 PF04479.13 KFY02917.1 - 9.6e-37 126.6 1.5 1.1e-36 126.4 1.5 1.0 1 0 0 1 1 1 1 RTA1 like protein Amidohydro_1 PF01979.20 KFY02918.1 - 3.9e-14 52.7 0.4 1.8e-13 50.6 0.4 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFY02918.1 - 1.5e-10 41.2 0.5 0.00025 20.7 0.1 2.3 1 1 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KFY02918.1 - 9e-05 21.4 1.0 0.0003 19.7 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02918.1 - 0.0034 17.5 0.9 0.0068 16.5 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 KFY02925.1 - 2.9e-37 127.9 0.5 2.9e-37 127.9 0.5 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFY02925.1 - 7.3e-18 65.6 0.1 2.3e-17 64.0 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFY02925.1 - 1.5e-16 59.8 0.0 3.4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 KFY02925.1 - 1e-13 51.4 2.2 1e-13 51.4 2.2 2.7 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFY02925.1 - 1.1e-06 28.6 0.0 8.1e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_efflux PF01545.21 KFY02927.1 - 1.5e-48 165.2 1.6 1.9e-48 164.8 1.6 1.1 1 0 0 1 1 1 1 Cation efflux family TM140 PF14985.6 KFY02927.1 - 0.021 14.4 0.3 0.05 13.1 0.3 1.6 1 0 0 1 1 1 0 TM140 protein family BPD_transp_2 PF02653.16 KFY02927.1 - 0.03 13.5 0.6 0.03 13.5 0.6 1.9 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component YdjM PF04307.14 KFY02927.1 - 0.074 12.4 0.1 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Sugar_tr PF00083.24 KFY02930.1 - 3.3e-38 131.7 27.0 1.5e-36 126.3 27.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02930.1 - 1e-31 110.2 30.9 1.6e-26 93.1 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KFY02930.1 - 0.0017 17.3 10.1 0.0037 16.2 0.9 2.6 3 0 0 3 3 3 2 Sugar-tranasporters, 12 TM DDE_1 PF03184.19 KFY02931.1 - 2.2e-10 40.5 0.0 4.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFY02931.1 - 0.00038 20.4 0.3 0.00096 19.1 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF4230 PF14014.6 KFY02931.1 - 0.074 13.3 1.3 1.2 9.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) HTH_psq PF05225.16 KFY02931.1 - 0.16 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Sugar_tr PF00083.24 KFY02932.1 - 3.9e-17 62.3 1.8 4.7e-17 62.0 1.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02932.1 - 0.0038 16.2 0.6 0.0042 16.1 0.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 KFY02941.1 - 5.2e-56 190.2 0.0 3e-36 125.1 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Ank_2 PF12796.7 KFY02998.1 - 2.4e-32 111.4 16.5 9.3e-15 55.0 2.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02998.1 - 7.8e-24 83.7 2.2 1.6e-08 34.9 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFY02998.1 - 6.9e-18 64.2 13.0 0.0022 18.3 0.1 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KFY02998.1 - 1.1e-09 37.7 6.2 1.1 10.0 0.0 6.2 6 0 0 6 6 5 3 Ankyrin repeat Helo_like_N PF17111.5 KFY02998.1 - 1.2e-09 37.9 0.8 3.2e-09 36.5 0.7 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KFY02998.1 - 2e-06 27.8 0.2 3.9e-05 23.6 0.2 2.5 1 1 0 1 1 1 1 NACHT domain SesA PF17107.5 KFY02998.1 - 0.0011 19.1 2.0 0.0068 16.6 1.2 2.5 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 KFY02998.1 - 0.0014 18.9 3.7 0.27 11.6 0.3 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF4446 PF14584.6 KFY02998.1 - 0.027 14.5 1.2 0.078 13.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) TMF_TATA_bd PF12325.8 KFY02998.1 - 0.21 11.8 2.7 0.34 11.1 1.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KFY02998.1 - 0.57 10.2 5.2 0.56 10.2 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FtsJ PF01728.19 KFY03000.1 - 8.2e-15 55.3 0.0 1.2e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KFY03000.1 - 0.18 11.4 0.1 0.47 10.0 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Sulf_transp PF04143.14 KFY03003.1 - 7.7e-36 124.2 15.3 7.7e-36 124.2 15.3 1.6 1 1 1 2 2 2 1 Sulphur transport Lactamase_B PF00753.27 KFY03004.1 - 6.5e-17 62.2 0.2 2e-16 60.6 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily UPF0242 PF06785.11 KFY03004.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1275 PF06912.11 KFY03005.1 - 2.5e-48 164.6 11.5 2.9e-48 164.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.6 KFY03005.1 - 0.046 13.4 5.7 1 9.0 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SirB PF04247.12 KFY03005.1 - 0.24 11.5 4.6 2 8.5 2.7 2.8 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB ATPase_gene1 PF09527.10 KFY03005.1 - 0.29 11.3 5.2 6.8 6.9 2.8 3.3 2 1 1 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ABC2_membrane PF01061.24 KFY03006.1 - 1.8e-28 99.4 26.1 2.9e-28 98.7 26.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFY03006.1 - 4.8e-27 95.1 0.1 7.4e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFY03006.1 - 4.4e-06 26.7 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFY03006.1 - 5.3e-06 26.9 0.1 8.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KFY03006.1 - 9.3e-05 22.0 0.0 0.00053 19.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFY03006.1 - 0.00017 21.9 0.1 0.00037 20.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFY03006.1 - 0.00024 21.0 0.0 0.00093 19.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFY03006.1 - 0.00039 20.0 0.1 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFY03006.1 - 0.0013 19.0 0.1 0.0022 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFY03006.1 - 0.0018 18.0 0.5 0.01 15.5 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KFY03006.1 - 0.0023 17.7 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 KFY03006.1 - 0.0026 16.9 0.1 0.0042 16.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KFY03006.1 - 0.0041 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFY03006.1 - 0.0051 16.9 0.1 0.015 15.4 0.0 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase NACHT PF05729.12 KFY03006.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KFY03006.1 - 0.0079 16.7 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFY03006.1 - 0.011 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KFY03006.1 - 0.011 15.4 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KFY03006.1 - 0.016 14.3 23.8 0.027 13.6 23.8 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_13 PF13166.6 KFY03006.1 - 0.018 13.7 0.1 0.31 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFY03006.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFY03006.1 - 0.039 14.3 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_35 PF14516.6 KFY03006.1 - 0.04 12.8 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.6 KFY03006.1 - 0.062 13.8 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFY03006.1 - 0.081 12.5 0.3 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 KFY03006.1 - 0.096 12.1 0.2 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MobB PF03205.14 KFY03006.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KFY03006.1 - 0.11 13.0 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KFY03006.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_14 PF13173.6 KFY03006.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFY03006.1 - 0.14 12.0 0.2 0.4 10.6 0.1 1.8 2 0 0 2 2 1 0 NTPase Septin PF00735.18 KFY03006.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KFY03006.1 - 0.21 11.5 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFY03006.1 - 0.26 10.4 0.3 0.68 9.1 0.1 1.7 1 1 1 2 2 2 0 NB-ARC domain Fungal_trans PF04082.18 KFY03007.1 - 3e-06 26.5 0.0 9.8e-06 24.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KFY03008.1 - 5.1e-10 38.8 0.0 8.9e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03008.1 - 1.3e-09 38.0 12.3 2.4e-09 37.2 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mrr_cat_2 PF13156.6 KFY03008.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease YscJ_FliF PF01514.17 KFY03008.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family CDO_I PF05995.12 KFY03009.1 - 2.8e-37 127.6 0.0 3.6e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I RFC1 PF08519.12 KFY03009.1 - 0.0068 16.6 0.0 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain PCO_ADO PF07847.12 KFY03009.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO AOX PF01786.17 KFY03010.1 - 3.7e-90 301.2 0.1 5.4e-90 300.7 0.1 1.3 1 0 0 1 1 1 1 Alternative oxidase TFIIA PF03153.13 KFY03022.1 - 0.42 10.6 17.7 0.55 10.2 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-MYND PF01753.18 KFY03025.1 - 4.2e-09 36.3 15.2 4.2e-09 36.3 15.2 2.9 3 0 0 3 3 3 1 MYND finger RdRP PF05183.12 KFY03027.1 - 2.4e-179 597.8 0.0 3.8e-179 597.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DEAD PF00270.29 KFY03028.1 - 0.0027 17.5 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ssDNA_TraI_N PF18272.1 KFY03028.1 - 0.02 14.9 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain NDT80_PhoG PF05224.12 KFY03030.1 - 2.1e-41 142.2 0.0 3e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Myb_DNA-binding PF00249.31 KFY03030.1 - 0.048 13.9 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain AAA PF00004.29 KFY03031.1 - 9.6e-42 142.5 0.0 2.2e-12 47.5 0.0 5.6 5 1 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KFY03031.1 - 2e-39 135.3 0.0 5.3e-39 133.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY03031.1 - 1.9e-25 90.1 35.4 9.4e-24 84.6 0.0 6.8 5 1 1 6 6 5 2 AAA domain AAA_19 PF13245.6 KFY03031.1 - 3e-18 66.5 0.0 3.6e-07 30.6 0.0 6.0 6 1 0 6 6 4 2 AAA domain AAA_30 PF13604.6 KFY03031.1 - 8.5e-17 61.5 14.7 0.0021 17.8 0.0 6.8 7 0 0 7 7 6 5 AAA domain AAA_lid_6 PF17866.1 KFY03031.1 - 2.1e-15 56.6 4.9 3.3e-06 27.2 1.2 4.2 4 0 0 4 4 3 2 AAA lid domain AAA_5 PF07728.14 KFY03031.1 - 1e-12 48.2 0.2 0.0049 16.9 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KFY03031.1 - 2.3e-10 40.2 0.1 0.23 10.8 0.0 4.6 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 KFY03031.1 - 4.9e-09 36.3 0.1 0.91 9.2 0.0 5.7 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KFY03031.1 - 9.6e-08 32.4 12.3 0.11 12.8 0.0 7.2 6 2 0 6 6 5 2 AAA domain IstB_IS21 PF01695.17 KFY03031.1 - 2.6e-07 30.5 0.1 3.8 7.2 0.0 4.8 4 0 0 4 4 4 2 IstB-like ATP binding protein RuvB_N PF05496.12 KFY03031.1 - 6.4e-07 29.3 4.1 0.31 10.8 0.0 5.3 5 1 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KFY03031.1 - 2e-06 27.3 4.0 0.034 13.4 0.0 6.6 7 1 1 8 8 8 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KFY03031.1 - 2e-06 27.6 2.6 1.3 8.7 0.0 5.0 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 KFY03031.1 - 2.8e-06 27.7 0.1 5.2 7.5 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_7 PF12775.7 KFY03031.1 - 1.4e-05 24.7 0.4 7.4 6.0 0.1 4.5 4 0 0 4 4 4 0 P-loop containing dynein motor region ResIII PF04851.15 KFY03031.1 - 7.2e-05 22.9 7.4 0.036 14.1 0.0 5.5 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KFY03031.1 - 8.6e-05 22.3 0.3 2 8.1 0.1 5.1 4 1 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.6 KFY03031.1 - 0.00023 21.7 12.5 2.1 8.9 0.0 5.6 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 KFY03031.1 - 0.00032 21.1 21.0 0.12 12.7 0.1 5.9 6 0 0 6 6 4 2 AAA ATPase domain Torsin PF06309.11 KFY03031.1 - 0.00053 20.1 0.1 42 4.3 0.0 4.4 4 0 0 4 4 4 0 Torsin PhoH PF02562.16 KFY03031.1 - 0.0018 17.8 0.2 10 5.5 0.0 4.6 5 0 0 5 5 5 0 PhoH-like protein ATPase PF06745.13 KFY03031.1 - 0.0069 15.8 2.4 9 5.6 0.0 4.3 4 0 0 4 4 4 0 KaiC NACHT PF05729.12 KFY03031.1 - 0.013 15.4 1.5 12 5.7 0.0 4.3 4 0 0 4 4 4 0 NACHT domain AAA_33 PF13671.6 KFY03031.1 - 0.013 15.7 23.4 0.061 13.5 0.0 5.9 6 0 0 6 6 4 0 AAA domain TsaE PF02367.17 KFY03031.1 - 0.016 15.2 0.9 3 7.8 0.1 4.0 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KFY03031.1 - 0.027 14.4 3.1 6.8 6.6 0.1 4.3 4 0 0 4 4 4 0 NTPase MCM PF00493.23 KFY03031.1 - 0.035 13.2 0.5 0.72 8.9 0.1 2.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_6 PF12774.7 KFY03031.1 - 0.08 11.9 0.4 12 4.7 0.1 3.3 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region UvrD-helicase PF00580.21 KFY03031.1 - 0.11 11.9 0.0 0.11 11.9 0.0 5.6 5 2 0 6 6 4 0 UvrD/REP helicase N-terminal domain AAA_2 PF07724.14 KFY03031.1 - 0.14 12.2 2.6 17 5.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain (Cdc48 subfamily) KTI12 PF08433.10 KFY03031.1 - 5.3 6.4 6.9 9.9 5.5 0.0 3.6 5 0 0 5 5 3 0 Chromatin associated protein KTI12 Pet127 PF08634.10 KFY03032.1 - 0.00014 21.4 0.1 0.061 12.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial protein Pet127 Piwi PF02171.17 KFY03033.1 - 2.6e-67 227.2 0.0 4.4e-67 226.4 0.0 1.4 1 0 0 1 1 1 1 Piwi domain Ribonuclease_3 PF00636.26 KFY03033.1 - 6.6e-45 152.0 0.0 1.7e-22 80.0 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFY03033.1 - 2.5e-34 118.2 0.0 1.1e-15 57.9 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KFY03033.1 - 1.5e-22 79.5 0.0 4.7e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Cauli_VI PF01693.16 KFY03033.1 - 8.9e-20 70.7 5.4 1.4e-09 38.1 0.8 3.0 2 0 0 2 2 2 2 Caulimovirus viroplasmin DEAD PF00270.29 KFY03033.1 - 1.2e-18 67.5 0.0 2.6e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ArgoN PF16486.5 KFY03033.1 - 8.4e-18 65.3 0.8 2.4e-17 63.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of argonaute Helicase_C PF00271.31 KFY03033.1 - 5.3e-14 52.5 0.0 1.5e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY03033.1 - 1.9e-12 47.5 0.0 4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ArgoL1 PF08699.10 KFY03033.1 - 1.1e-11 44.2 1.0 4e-11 42.4 1.0 2.1 1 0 0 1 1 1 1 Argonaute linker 1 domain IBR PF01485.21 KFY03033.1 - 1.5e-10 41.2 36.8 1.3e-05 25.3 8.0 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ArgoL2 PF16488.5 KFY03033.1 - 7.6e-08 32.6 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain Flavi_DEAD PF07652.14 KFY03033.1 - 0.0033 17.4 0.1 0.012 15.6 0.1 1.9 1 1 0 1 1 1 1 Flavivirus DEAD domain ArgoMid PF16487.5 KFY03033.1 - 0.0049 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute RdRP PF05183.12 KFY03034.1 - 8.1e-107 358.3 0.0 1.2e-106 357.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 KFY03034.1 - 1.6e-50 171.5 0.1 2.7e-50 170.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY03034.1 - 3.2e-42 145.1 1.7 1.9e-20 73.8 0.3 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KFY03034.1 - 9.3e-14 51.6 0.9 4.2e-13 49.4 0.2 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFY03034.1 - 4.9e-13 49.6 0.4 2.1e-12 47.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFY03034.1 - 1.4e-07 31.7 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFY03034.1 - 1e-05 25.4 2.5 0.092 12.5 0.3 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KFY03034.1 - 3e-05 24.0 0.0 5.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KFY03034.1 - 0.00021 21.0 0.2 0.067 12.7 0.1 2.8 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KFY03034.1 - 0.00075 19.0 0.1 0.0034 16.9 0.1 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KFY03034.1 - 0.00082 19.8 0.0 0.0039 17.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFY03034.1 - 0.001 19.4 0.0 0.0038 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFY03034.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 KFY03034.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFY03034.1 - 0.15 12.2 0.1 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFY03034.1 - 0.15 11.3 0.7 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KFY03035.1 - 4.3e-28 98.6 0.0 4.8e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY03035.1 - 0.00011 22.6 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 KFY03035.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 KFY03035.1 - 0.0035 17.9 0.0 0.005 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KFY03035.1 - 0.0049 17.0 0.0 0.0077 16.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 KFY03035.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_15 PF13175.6 KFY03035.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFY03035.1 - 0.072 13.2 0.1 0.1 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFY03035.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KFY03035.1 - 0.088 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFY03035.1 - 0.098 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.20 KFY03035.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.13 KFY03035.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFY03035.1 - 0.18 12.1 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain muHD PF10291.9 KFY03037.1 - 0.086 12.3 0.1 0.098 12.1 0.1 1.1 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ADK PF00406.22 KFY03038.1 - 2.7e-16 60.0 0.1 7.5e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KFY03038.1 - 2.4e-12 47.4 0.0 5e-07 30.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 KFY03038.1 - 4e-06 27.0 0.0 0.023 14.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 KFY03038.1 - 0.00011 22.0 0.6 0.0049 16.6 0.4 2.2 1 1 1 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 KFY03038.1 - 0.0008 20.0 0.3 0.083 13.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KFY03038.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KFY03038.1 - 0.0054 17.0 0.0 0.01 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KFY03038.1 - 0.055 13.3 0.3 2.8 7.8 0.1 2.1 1 1 1 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 KFY03038.1 - 0.11 11.8 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin CYTH PF01928.21 KFY03039.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 CYTH domain UPRTase PF14681.6 KFY03040.1 - 1.9e-40 138.5 0.1 3.8e-40 137.6 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 KFY03040.1 - 9.4e-24 84.4 0.0 2.6e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 KFY03040.1 - 3.4e-23 83.0 0.5 1.4e-22 81.0 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 KFY03040.1 - 0.00012 22.5 1.4 0.00079 19.8 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 KFY03040.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PRTase_2 PF15609.6 KFY03040.1 - 0.00047 19.7 0.0 0.0057 16.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase AAA_18 PF13238.6 KFY03040.1 - 0.0008 20.0 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KFY03040.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Pribosyltran PF00156.27 KFY03040.1 - 0.0055 16.2 0.2 0.1 12.1 0.2 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain MeaB PF03308.16 KFY03040.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KFY03040.1 - 0.015 15.8 0.1 0.094 13.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydrolase PF00702.26 KFY03040.1 - 0.032 14.5 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NB-ARC PF00931.22 KFY03040.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KFY03040.1 - 0.045 13.5 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFY03040.1 - 0.067 13.5 0.1 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KFY03040.1 - 0.079 12.1 0.1 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KFY03040.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KFY03040.1 - 0.17 12.1 0.3 2.5 8.3 0.3 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_U4 PF03419.13 KFY03040.1 - 0.21 10.9 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA BTB PF00651.31 KFY03043.1 - 4.7e-06 26.8 0.1 9.8e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain HicA_toxin PF07927.12 KFY03045.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Glyco_hydro_76 PF03663.14 KFY03063.1 - 3.9e-94 316.2 6.6 4.4e-94 316.0 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 F-box-like PF12937.7 KFY03065.1 - 0.00063 19.6 0.5 0.00063 19.6 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KFY03065.1 - 0.00091 19.1 0.7 0.0026 17.6 0.1 2.0 2 0 0 2 2 2 1 F-box F-box PF00646.33 KFY03065.1 - 3.4 7.7 8.6 0.15 11.9 0.4 2.9 3 0 0 3 3 3 0 F-box domain Aldedh PF00171.22 KFY03066.1 - 1.9e-131 438.8 0.2 2.3e-131 438.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.8 KFY03067.1 - 5.4e-23 81.4 0.2 1.8e-22 79.7 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03067.1 - 2.5e-07 30.7 13.4 5.7e-07 29.6 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KFY03068.1 - 9.1e-24 83.9 0.6 1.6e-23 83.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY03068.1 - 1.1e-13 51.0 0.0 8.3e-11 41.7 0.0 2.8 2 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFY03068.1 - 2.6e-11 44.7 0.0 5.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KFY03068.1 - 0.018 14.7 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LEA_5 PF00477.17 KFY03068.1 - 0.043 14.3 0.2 0.11 13.0 0.2 1.6 1 1 0 1 1 1 0 Small hydrophilic plant seed protein ADH_N_2 PF16884.5 KFY03068.1 - 0.096 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ICL PF00463.21 KFY03069.1 - 5.9e-195 648.7 0.2 6.8e-195 648.5 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFY03069.1 - 5.1e-10 39.2 0.2 2.4e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF5333 PF17267.2 KFY03069.1 - 0.084 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Gp_dh_C PF02800.20 KFY03069.1 - 0.45 10.1 2.5 7.5 6.1 0.1 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GFO_IDH_MocA_C PF02894.17 KFY03070.1 - 1.7e-17 63.5 0.1 4.9e-17 62.0 0.2 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 KFY03070.1 - 7.6e-17 62.3 0.0 1.6e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.24 KFY03072.1 - 5.5e-68 229.9 16.1 6.3e-68 229.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03072.1 - 2.7e-19 69.3 25.4 8.2e-13 48.0 4.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 KFY03072.1 - 0.65 8.7 5.1 0.77 8.5 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4383 PF14325.6 KFY03072.1 - 0.66 10.3 11.7 0.64 10.3 9.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) Glyco_hydro_43 PF04616.14 KFY03073.1 - 9.6e-67 225.3 3.1 1.3e-66 224.9 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFY03073.1 - 1.3e-09 38.1 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF4896 PF16237.5 KFY03073.1 - 0.076 12.9 0.5 0.18 11.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) Reg_prop PF07494.11 KFY03073.1 - 0.25 11.7 1.9 30 5.3 0.1 3.7 3 0 0 3 3 3 0 Two component regulator propeller WD40 PF00400.32 KFY03079.1 - 2e-117 379.7 55.6 3.2e-10 40.4 0.1 13.9 13 0 0 13 13 13 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03079.1 - 3.3e-40 136.3 10.7 0.0041 17.4 0.0 13.5 1 1 11 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain SesA PF17107.5 KFY03079.1 - 2.2e-36 124.7 0.0 5.6e-36 123.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PD40 PF07676.12 KFY03079.1 - 2e-21 75.4 3.4 0.98 9.4 0.0 11.6 11 0 0 11 11 11 5 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFY03079.1 - 7.5e-15 54.7 13.6 0.71 8.8 0.1 11.1 1 1 11 12 12 12 6 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KFY03079.1 - 7.6e-11 42.2 0.2 1.8e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KFY03079.1 - 3.1e-08 33.3 0.0 7.9 5.7 0.0 7.3 3 2 4 8 8 8 1 WD40-like domain Proteasome_A_N PF10584.9 KFY03079.1 - 1.3e-06 28.0 2.4 13 5.6 0.0 8.8 11 0 0 11 11 11 1 Proteasome subunit A N-terminal signature Frtz PF11768.8 KFY03079.1 - 2.6e-05 22.8 0.0 0.13 10.6 0.0 4.4 3 2 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz NACHT_sigma PF17106.5 KFY03079.1 - 3.3e-05 23.9 19.7 0.0057 16.8 19.7 2.9 1 1 0 1 1 1 1 Sigma domain on NACHT-NTPases CobA_CobO_BtuR PF02572.15 KFY03079.1 - 0.0031 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ResIII PF04851.15 KFY03079.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_capsid PF06112.11 KFY03080.1 - 3 7.9 11.7 6 6.9 11.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DDE_Tnp_1_assoc PF13808.6 KFY03081.1 - 0.072 13.1 0.1 1.7 8.7 0.0 2.3 2 1 0 2 2 2 0 DDE_Tnp_1-associated Patatin PF01734.22 KFY03083.1 - 2.1e-09 37.9 0.0 6.8e-09 36.2 0.0 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Herpes_DNAp_acc PF04929.12 KFY03105.1 - 0.45 9.4 3.4 0.63 8.9 3.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF929 PF06053.11 KFY03107.1 - 0.058 12.7 0.1 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF929) APH PF01636.23 KFY03108.1 - 6.7e-15 55.7 0.0 1.7e-14 54.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFY03108.1 - 5.5e-07 28.8 0.0 9.5e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFY03108.1 - 0.00027 20.3 0.0 0.00076 18.9 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFY03108.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ofd1_CTDD PF10637.9 KFY03108.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Pkinase PF00069.25 KFY03108.1 - 0.099 12.0 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain RRM_1 PF00076.22 KFY03112.1 - 3.1e-07 30.1 0.0 5.9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY03112.1 - 3.6e-05 23.5 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFY03112.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Transket_pyr PF02779.24 KFY03113.1 - 1.2e-46 158.6 0.0 2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFY03113.1 - 4.6e-36 123.4 0.0 1.4e-35 121.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.10 KFY03113.1 - 7e-20 71.1 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KFY03113.1 - 8.3e-18 64.8 0.0 2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03113.1 - 3.9e-17 62.8 0.0 9.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03113.1 - 6.1e-16 58.6 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFY03113.1 - 3.8e-12 46.1 0.1 6.3e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFY03113.1 - 3.8e-10 39.8 0.0 7.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY03113.1 - 3.7e-09 37.2 0.0 1e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY03113.1 - 9.7e-09 34.9 0.0 4.9e-08 32.6 0.0 2.1 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFY03113.1 - 0.00015 21.6 0.1 0.00033 20.5 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KFY03113.1 - 0.00068 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFY03113.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KFY03113.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KFY03113.1 - 0.022 14.1 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_24 PF13578.6 KFY03113.1 - 0.067 14.2 0.0 0.27 12.3 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFY03113.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KFY03113.1 - 0.095 11.8 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KFY03113.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KFY03113.1 - 0.14 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW YabA PF06156.13 KFY03113.1 - 0.17 12.5 0.6 0.45 11.2 0.6 1.7 1 0 0 1 1 1 0 Initiation control protein YabA PQ-loop PF04193.14 KFY03117.1 - 9e-21 73.4 12.7 1.4e-13 50.4 2.7 2.6 3 0 0 3 3 3 2 PQ loop repeat DUF5516 PF17637.2 KFY03117.1 - 0.14 12.0 1.8 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5516) Med8 PF10232.9 KFY03118.1 - 7.7e-27 94.4 0.0 9.7e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Spt5_N PF11942.8 KFY03118.1 - 0.022 15.8 3.4 0.054 14.5 3.4 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Acetyltransf_1 PF00583.25 KFY03119.1 - 5.8e-09 36.2 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY03119.1 - 5.7e-06 26.3 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY03119.1 - 2.7e-05 24.1 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFY03119.1 - 0.0001 22.6 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFY03119.1 - 0.0029 17.8 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY03119.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Complex1_LYR PF05347.15 KFY03120.1 - 8.1e-17 61.0 0.2 1.3e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFY03120.1 - 0.013 16.2 0.0 0.019 15.7 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RecO_N PF11967.8 KFY03120.1 - 0.063 13.3 0.5 0.39 10.7 0.1 2.1 1 1 1 2 2 2 0 Recombination protein O N terminal PIG-S PF10510.9 KFY03121.1 - 9.6e-126 420.6 0.0 1.3e-125 420.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Ribosomal_L36 PF00444.18 KFY03121.1 - 3.3e-19 68.8 9.0 3.3e-19 68.8 9.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L36 Acetyltransf_1 PF00583.25 KFY03123.1 - 0.0039 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ycf1 PF05758.12 KFY03123.1 - 0.0085 14.0 0.1 0.011 13.6 0.1 1.1 1 0 0 1 1 1 1 Ycf1 Acetyltransf_10 PF13673.7 KFY03123.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY03123.1 - 0.088 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.6 KFY03124.1 - 1.4e-19 70.5 0.0 2.7e-19 69.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03124.1 - 1.9e-10 41.3 0.0 4.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY03124.1 - 2.9e-07 31.2 0.0 1e-06 29.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY03124.1 - 1.5e-06 28.8 0.0 2.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03124.1 - 4e-05 23.5 0.0 0.00067 19.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFY03124.1 - 0.00042 19.9 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFY03124.1 - 0.0014 18.1 0.0 0.0062 16.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFY03124.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KFY03124.1 - 0.0034 16.7 0.0 0.052 12.9 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 KFY03124.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 KFY03124.1 - 0.18 11.2 0.0 0.55 9.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase GidB PF02527.15 KFY03124.1 - 0.25 10.6 0.0 0.45 9.8 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PTS_EIIA_2 PF00359.22 KFY03125.1 - 0.096 12.6 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Pkinase_fungal PF17667.1 KFY03126.1 - 1.1e-131 439.4 0.0 1.4e-131 439.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Vac14_Fig4_bd PF11916.8 KFY03127.1 - 0.036 13.7 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding PHD PF00628.29 KFY03128.1 - 0.0023 17.8 11.7 0.0057 16.5 11.7 1.7 1 0 0 1 1 1 1 PHD-finger Peptidase_C48 PF02902.19 KFY03128.1 - 0.0039 17.0 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Atg14 PF10186.9 KFY03128.1 - 0.0059 15.7 3.1 0.012 14.7 3.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 KFY03128.1 - 0.03 14.3 0.6 0.093 12.7 0.6 1.9 1 0 0 1 1 1 0 WTAP/Mum2p family PHD_4 PF16866.5 KFY03128.1 - 0.084 13.0 9.3 0.28 11.3 9.3 1.9 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.19 KFY03128.1 - 0.14 12.2 4.4 0.57 10.2 4.4 2.2 1 0 0 1 1 1 0 AT hook motif AAA_16 PF13191.6 KFY03130.1 - 6.6e-06 26.6 0.1 2.6e-05 24.7 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFY03130.1 - 6.6e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cutinase PF01083.22 KFY03130.1 - 0.00018 21.5 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Cutinase AAA_22 PF13401.6 KFY03130.1 - 0.00018 21.8 0.0 0.0032 17.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.7 KFY03130.1 - 0.00047 20.8 0.0 0.0015 19.1 0.0 1.9 2 0 0 2 2 1 1 Alpha/beta hydrolase family RE_XamI PF09572.10 KFY03130.1 - 0.0019 18.0 1.1 9.5 5.8 0.0 3.7 3 0 0 3 3 3 0 XamI restriction endonuclease Arabinose_Iso_C PF11762.8 KFY03130.1 - 0.0038 17.0 3.0 5.6 6.8 0.0 4.5 5 0 0 5 5 5 1 L-arabinose isomerase C-terminal domain DUF726 PF05277.12 KFY03130.1 - 0.0078 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3089 PF11288.8 KFY03130.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 KFY03130.1 - 0.037 13.3 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KFY03130.1 - 0.038 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.22 KFY03130.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2974 PF11187.8 KFY03130.1 - 0.058 12.9 0.0 5.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) DUF900 PF05990.12 KFY03130.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KFY03130.1 - 0.076 12.7 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_1 PF00561.20 KFY03130.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4350 PF14258.6 KFY03130.1 - 0.1 13.1 1.2 70 4.0 0.0 6.3 7 1 1 8 8 8 0 Domain of unknown function (DUF4350) LIDHydrolase PF10230.9 KFY03130.1 - 0.16 11.5 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAA_assoc_C PF09821.9 KFY03130.1 - 0.69 10.5 13.8 11 6.6 0.1 7.4 5 2 1 9 9 7 0 C-terminal AAA-associated domain DUF2892 PF11127.8 KFY03130.1 - 6.8 6.8 6.9 20 5.3 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2892) Spc7_N PF15402.6 KFY03131.1 - 7.1e-226 752.7 77.3 2.3e-225 751.0 77.3 2.5 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KFY03131.1 - 1.3e-116 388.8 5.4 1.3e-116 388.8 5.4 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KFY03131.1 - 8.6e-18 64.2 0.6 1.8e-17 63.2 0.6 1.6 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17_N PF16205.5 KFY03132.1 - 2.6e-33 114.2 0.3 4.2e-33 113.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFY03132.1 - 7e-26 90.1 0.2 1.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 PfkB PF00294.24 KFY03133.1 - 9.4e-42 143.3 1.3 1.2e-41 143.0 1.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 KFY03134.1 - 1.1e-08 35.0 11.1 2.1e-08 34.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY03134.1 - 2.8e-06 26.4 2.0 0.00038 19.4 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain HypA PF01155.19 KFY03134.1 - 7.7 6.6 6.8 9.4 6.3 5.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 KFY03135.1 - 1.3e-109 367.1 30.8 2.3e-109 366.3 30.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03135.1 - 1.9e-21 76.4 60.7 1.6e-13 50.4 24.9 3.6 2 1 2 4 4 4 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KFY03135.1 - 1.1e-11 44.2 0.1 2.1e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_2 PF13347.6 KFY03135.1 - 0.0001 21.0 9.0 0.0001 21.0 9.0 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein Methyltransf_11 PF08241.12 KFY03136.1 - 2.8e-11 43.9 0.0 6.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03136.1 - 5.5e-10 39.8 0.0 1.3e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Fig1 PF12351.8 KFY03136.1 - 9.5e-10 38.7 4.9 9.5e-10 38.7 4.9 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Methyltransf_23 PF13489.6 KFY03136.1 - 1.2e-09 38.2 0.0 3.5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03136.1 - 1.5e-08 34.6 0.0 3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY03136.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY03136.1 - 1.5e-05 25.7 0.0 5.1e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KFY03136.1 - 0.0032 17.2 0.0 0.0081 15.8 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KFY03136.1 - 0.037 14.0 0.4 0.086 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KFY03136.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase E1-E2_ATPase PF00122.20 KFY03136.1 - 0.61 9.6 3.2 1.3 8.5 3.2 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Pkinase PF00069.25 KFY03138.1 - 0.001 18.5 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CzcE PF16986.5 KFY03138.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE AAA_16 PF13191.6 KFY03139.1 - 5.7e-08 33.3 0.1 3.1e-07 30.9 0.1 2.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFY03139.1 - 3.6e-07 30.3 0.0 1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain HTH_Tnp_Tc5 PF03221.16 KFY03139.1 - 1e-06 28.7 0.1 12 6.0 0.0 9.5 9 2 2 11 11 11 1 Tc5 transposase DNA-binding domain AAA_22 PF13401.6 KFY03139.1 - 5.6e-05 23.4 0.5 0.0034 17.7 0.0 4.2 4 1 0 4 4 4 1 AAA domain DUF3140 PF11338.8 KFY03139.1 - 0.0062 16.9 4.5 5 7.6 0.0 4.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3140) RNA_helicase PF00910.22 KFY03139.1 - 0.029 14.8 0.0 0.14 12.6 0.0 2.3 1 0 0 1 1 1 0 RNA helicase CTP_transf_3 PF02348.19 KFY03139.1 - 0.034 14.1 4.9 1.1 9.1 0.2 5.2 4 2 3 7 7 7 0 Cytidylyltransferase BTB PF00651.31 KFY03140.1 - 0.00024 21.3 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-3CxxC PF13695.6 KFY03141.1 - 2e-16 60.3 0.0 3.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding domain Ndc1_Nup PF09531.10 KFY03141.1 - 0.063 12.0 0.7 0.068 11.8 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KFY03141.1 - 10 5.6 10.3 13 5.2 10.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ank_3 PF13606.6 KFY03146.1 - 0.0027 18.1 0.0 0.77 10.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KFY03146.1 - 0.0049 17.4 0.0 0.25 12.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY03146.1 - 0.0094 16.5 0.0 0.032 14.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFY03146.1 - 0.094 13.2 0.0 2.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat E1-E2_ATPase PF00122.20 KFY03151.1 - 1.2e-32 112.9 3.4 1.2e-32 112.9 3.4 2.6 3 1 0 3 3 3 1 E1-E2 ATPase Big_6 PF17936.1 KFY03151.1 - 0.1 12.9 0.9 0.19 12.0 0.9 1.5 1 0 0 1 1 1 0 Bacterial Ig domain DUF5383 PF17355.2 KFY03151.1 - 0.13 12.6 0.1 0.65 10.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5383) adh_short PF00106.25 KFY03162.1 - 5.9e-27 94.4 0.4 9.5e-26 90.5 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY03162.1 - 4e-15 56.0 0.1 1.8e-14 53.9 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HsbA PF12296.8 KFY03162.1 - 2.4e-05 24.7 0.0 5.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Hydrophobic surface binding protein A KR PF08659.10 KFY03162.1 - 4.1e-05 23.6 0.1 0.00017 21.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Phage_capsid PF05065.13 KFY03162.1 - 0.097 12.0 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Phage capsid family Zn_clus PF00172.18 KFY03163.1 - 1.8e-07 31.2 9.0 3.5e-07 30.2 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG7 PF10191.9 KFY03163.1 - 0.017 13.4 0.3 0.024 12.9 0.3 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Zn_clus PF00172.18 KFY03164.1 - 6e-09 35.9 9.8 1.8e-08 34.4 9.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY03164.1 - 2.5e-07 29.8 0.1 4e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain YaaC PF14175.6 KFY03164.1 - 0.059 12.6 0.7 0.1 11.8 0.7 1.3 1 0 0 1 1 1 0 YaaC-like Protein adh_short PF00106.25 KFY03165.1 - 4.4e-32 111.1 0.0 3.5e-25 88.6 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY03165.1 - 3e-21 76.1 0.0 1.1e-14 54.6 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY03165.1 - 6e-09 36.1 0.0 9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain TIR PF01582.20 KFY03165.1 - 0.13 12.0 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 TIR domain DUF3176 PF11374.8 KFY03166.1 - 0.0091 16.2 2.3 0.0091 16.2 2.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) ADH_N PF08240.12 KFY03167.1 - 1.3e-21 76.5 5.7 2.4e-21 75.7 5.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY03167.1 - 1.1e-17 64.2 0.0 2.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY03167.1 - 0.00016 21.1 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFY03167.1 - 0.0028 17.0 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFY03167.1 - 0.021 14.2 0.3 0.037 13.4 0.3 1.3 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KFY03167.1 - 0.042 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhzC-PhzF PF02567.16 KFY03168.1 - 5.7e-39 134.3 0.1 8.9e-39 133.6 0.1 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Amidohydro_3 PF07969.11 KFY03169.1 - 3.3e-71 241.2 0.7 3.7e-71 241.0 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KFY03169.1 - 2.9e-10 40.0 0.3 6.7e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF4238 PF14022.6 KFY03170.1 - 1e-67 228.6 0.1 1.7e-67 227.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Ank_2 PF12796.7 KFY03187.1 - 1.7e-35 121.4 0.0 4.6e-14 52.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY03187.1 - 8.8e-35 118.3 0.0 6e-09 36.0 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFY03187.1 - 6.5e-24 83.3 0.1 0.0012 19.2 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KFY03187.1 - 1.1e-22 77.6 0.0 0.00095 19.5 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 KFY03187.1 - 1.9e-22 79.3 0.0 8.9e-06 26.2 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) S4_2 PF13275.6 KFY03187.1 - 0.037 13.8 2.8 14 5.6 0.0 4.5 5 0 0 5 5 5 0 S4 domain F-box PF00646.33 KFY03187.1 - 0.053 13.4 0.2 0.096 12.6 0.2 1.4 1 0 0 1 1 1 0 F-box domain DUF1604 PF07713.13 KFY03187.1 - 0.098 12.5 0.0 18 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1604) Pkinase PF00069.25 KFY03198.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.17 KFY03199.1 - 0.0029 17.6 2.4 0.4 10.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03199.1 - 0.029 15.2 0.0 21 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03199.1 - 0.036 14.3 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03199.1 - 0.066 13.3 0.7 74 3.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KFY03200.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFY03200.1 - 0.04 14.3 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFY03200.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFY03200.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase HalX PF08663.10 KFY03251.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 HalX domain SRF-TF PF00319.18 KFY03252.1 - 1.4e-06 27.6 0.3 2.1e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ferric_reduct PF01794.19 KFY03253.1 - 1.1e-05 25.5 0.6 1.1e-05 25.5 0.6 2.0 2 1 1 3 3 3 1 Ferric reductase like transmembrane component CKS PF01111.19 KFY03258.1 - 1.2e-34 118.3 1.1 1.6e-34 117.9 1.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 KFY03259.1 - 1.1e-29 102.3 0.8 3.8e-15 55.7 0.1 2.4 2 0 0 2 2 2 2 Bromodomain HSP70 PF00012.20 KFY03260.1 - 1.2e-212 707.4 4.5 1.5e-212 707.0 4.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFY03260.1 - 1e-14 54.1 0.2 8.8e-11 41.2 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KFY03260.1 - 6.4e-05 22.8 0.0 0.00017 21.4 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KFY03260.1 - 0.026 13.5 0.1 0.19 10.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KFY03260.1 - 0.057 13.9 3.2 9.8 6.7 0.1 3.7 3 1 0 3 3 3 0 Cell division protein FtsA ATP-synt_DE PF00401.20 KFY03260.1 - 0.27 11.5 4.5 0.76 10.1 1.7 2.7 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NAD-GH PF10712.9 KFY03261.1 - 1.4e-07 30.4 0.0 1.6e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase Pkinase PF00069.25 KFY03263.1 - 3.3e-07 30.0 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03263.1 - 0.0039 16.5 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Toxin_15 PF07906.13 KFY03263.1 - 0.089 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region AAA PF00004.29 KFY03265.1 - 3.4e-06 27.5 0.0 4.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GRAM PF02893.20 KFY03265.1 - 0.029 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.8 KFY03265.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Zot PF05707.12 KFY03265.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF547 PF04784.14 KFY03266.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Pkinase PF00069.25 KFY03268.1 - 1.4e-21 77.1 0.0 8.5e-16 58.1 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03268.1 - 7.3e-05 22.2 0.0 0.0042 16.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3435 PF11917.8 KFY03270.1 - 4.6e-67 226.8 0.0 4.8e-65 220.1 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Aida_N PF08910.10 KFY03270.1 - 0.15 12.5 0.5 26 5.3 0.1 3.1 3 0 0 3 3 3 0 Aida N-terminus FA_desaturase PF00487.24 KFY03272.1 - 5.6e-09 36.2 19.3 1.2e-08 35.1 19.3 1.5 1 0 0 1 1 1 1 Fatty acid desaturase SIR2 PF02146.17 KFY03273.1 - 1.6e-16 60.8 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family CCDC106 PF15794.5 KFY03273.1 - 0.88 9.2 3.7 21 4.8 0.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 Ferric_reduct PF01794.19 KFY03274.1 - 1.5e-12 47.8 7.0 1.5e-12 47.8 7.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY03274.1 - 2.4e-08 34.0 0.0 1.1e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFY03274.1 - 0.00019 21.6 0.0 0.00064 19.9 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Glyoxalase_2 PF12681.7 KFY03274.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain DUF4870 PF09685.10 KFY03274.1 - 2.8 8.1 12.0 0.64 10.1 4.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF3723 PF12520.8 KFY03276.1 - 1.6e-107 360.3 0.0 4.6e-107 358.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Retrotrans_gag PF03732.17 KFY03276.1 - 0.18 12.1 2.1 2.8 8.3 0.3 3.5 2 1 1 3 3 3 0 Retrotransposon gag protein DUF2951 PF11166.8 KFY03278.1 - 6.5 7.0 14.9 0.098 12.9 6.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3435 PF11917.8 KFY03279.1 - 5.9e-43 147.4 0.1 7.3e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF2960 PF11173.8 KFY03279.1 - 0.099 13.1 0.1 0.79 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) DUF3435 PF11917.8 KFY03298.1 - 1.2e-14 54.1 0.0 1.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TPR_14 PF13428.6 KFY03300.1 - 0.019 15.7 0.1 18 6.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY03300.1 - 0.1 12.8 0.7 16 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFY03302.1 - 1.1e-09 38.0 0.1 2.1e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03302.1 - 8.7e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Nramp PF01566.18 KFY03307.1 - 1.4e-88 297.3 16.3 3.2e-88 296.1 16.3 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Copper-fist PF00649.18 KFY03308.1 - 7.2e-09 35.0 7.7 1.5e-08 34.0 7.7 1.6 1 1 0 1 1 1 1 Copper fist DNA binding domain Abhydrolase_3 PF07859.13 KFY03309.1 - 1.6e-40 139.3 0.0 2.1e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFY03309.1 - 1e-07 31.2 0.1 2.2e-07 30.2 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 KFY03309.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cu-oxidase_2 PF07731.14 KFY03310.1 - 6.7e-42 142.5 0.8 9.5e-35 119.3 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFY03310.1 - 1.3e-35 122.0 2.1 3.8e-35 120.5 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KFY03310.1 - 2.4e-16 60.2 0.1 3.4e-11 43.5 0.1 2.8 2 0 0 2 2 2 2 Multicopper oxidase Ctr PF04145.15 KFY03310.1 - 1.6e-05 25.5 1.0 4.5e-05 24.1 1.0 1.7 1 0 0 1 1 1 1 Ctr copper transporter family Tim17 PF02466.19 KFY03310.1 - 0.82 10.1 7.6 0.03 14.7 1.4 1.8 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Cu-oxidase_3 PF07732.15 KFY03313.1 - 3.6e-18 65.7 0.5 2.1e-16 60.0 0.2 2.1 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KFY03313.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY03313.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase PAZ_siRNAbind PF12212.8 KFY03313.1 - 0.29 10.9 0.6 10 5.9 0.0 2.3 2 0 0 2 2 2 0 PAZ domain Ferric_reduct PF01794.19 KFY03341.1 - 6.1e-21 74.8 9.3 6.1e-21 74.8 9.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY03341.1 - 1.7e-12 47.4 0.0 7.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 KFY03341.1 - 0.04 14.1 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain HMA PF00403.26 KFY03343.1 - 2.6e-29 101.4 0.1 3.4e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain DUF4428 PF14471.6 KFY03343.1 - 0.075 13.0 0.9 22 5.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Fer2 PF00111.27 KFY03343.1 - 0.12 12.3 0.3 18 5.3 0.0 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain E1-E2_ATPase PF00122.20 KFY03349.1 - 1.1e-52 178.2 0.1 2.8e-52 176.9 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFY03349.1 - 1.2e-37 130.2 0.1 2.1e-37 129.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFY03349.1 - 5.2e-27 94.1 0.1 3.2e-11 43.5 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFY03349.1 - 0.00047 20.0 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KFY03349.1 - 0.022 14.8 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat DUF4428 PF14471.6 KFY03349.1 - 0.47 10.4 1.5 52 3.9 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) ADAM_spacer1 PF05986.14 KFY03359.1 - 1.7e-06 28.0 4.8 0.79 9.8 0.1 4.4 2 2 2 4 4 4 3 ADAM-TS Spacer 1 Bactofilin PF04519.13 KFY03359.1 - 0.018 15.3 17.0 46 4.4 17.0 2.9 1 1 0 1 1 1 0 Polymer-forming cytoskeletal AsmA_2 PF13502.6 KFY03359.1 - 0.097 12.2 7.0 0.89 9.0 0.4 2.8 1 1 1 2 2 2 0 AsmA-like C-terminal region Dockerin_1 PF00404.18 KFY03359.1 - 7.5 6.8 24.6 67 3.8 0.1 6.6 6 1 0 6 6 6 0 Dockerin type I domain VCBS PF13517.6 KFY03360.1 - 1.9e-29 102.0 52.2 7.5e-15 55.3 3.0 8.3 4 2 6 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFY03360.1 - 3.7e-14 53.5 1.5 3.7e-14 53.5 1.5 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY03360.1 - 2.6e-08 34.1 0.1 4.3e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KFY03360.1 - 1.5e-05 24.5 10.3 0.43 9.9 0.0 6.9 5 2 3 8 8 8 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.6 KFY03360.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KFY03360.1 - 0.00087 19.4 36.3 0.12 12.5 1.4 6.8 6 0 0 6 6 6 4 FG-GAP repeat PliI PF16743.5 KFY03360.1 - 0.1 12.4 0.3 11 5.8 0.0 4.0 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme RE_SinI PF09570.10 KFY03361.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 SinI restriction endonuclease ASFV_J13L PF05568.11 KFY03361.1 - 0.004 16.9 7.1 6.1e+02 0.0 7.1 5.1 1 1 0 1 1 1 0 African swine fever virus J13L protein RsmJ PF04378.13 KFY03362.1 - 0.16 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ zf-RING_2 PF13639.6 KFY03363.1 - 3.5e-05 24.0 10.2 6.8e-05 23.1 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KFY03363.1 - 0.00018 21.5 5.1 0.0005 20.1 5.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFY03363.1 - 0.00079 19.7 6.9 0.002 18.4 6.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KFY03363.1 - 0.0055 16.8 7.9 0.014 15.5 7.9 1.7 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 KFY03363.1 - 0.007 16.0 6.5 0.013 15.1 6.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type MatE PF01554.18 KFY03363.1 - 0.0084 15.8 0.9 0.0084 15.8 0.9 3.3 3 0 0 3 3 3 1 MatE FANCL_C PF11793.8 KFY03363.1 - 0.021 15.0 5.5 0.056 13.6 5.5 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 KFY03363.1 - 0.37 10.9 5.4 0.77 9.9 5.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 KFY03363.1 - 0.98 9.3 10.5 2 8.3 10.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFY03363.1 - 1.6 8.6 7.3 4.6 7.2 7.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KFY03363.1 - 2.2 8.3 7.0 7.7 6.5 3.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KFY03363.1 - 2.3 8.2 7.0 3.9 7.5 7.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KFY03363.1 - 4.1 7.8 9.5 9.2 6.7 9.5 1.6 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 KFY03363.1 - 5.8 6.9 6.7 2.9 7.8 4.4 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 KFY03365.1 - 2.4e-12 46.8 0.0 9.4e-12 44.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03365.1 - 5.8e-11 42.2 0.0 8.2e-10 38.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lyase_catalyt PF09093.11 KFY03366.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic DDE_5 PF13546.6 KFY03374.1 - 0.095 12.0 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Ank_2 PF12796.7 KFY03375.1 - 5.7e-29 100.5 6.6 8.3e-11 42.3 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY03375.1 - 2.7e-14 53.0 2.0 1.6e-05 25.1 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFY03375.1 - 3.4e-13 49.8 0.3 0.001 19.6 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY03375.1 - 4.9e-08 32.6 0.9 0.12 13.0 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KFY03375.1 - 5.1e-07 29.9 2.2 0.75 10.4 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Tropomyosin_1 PF12718.7 KFY03375.1 - 0.12 12.5 3.4 0.26 11.4 3.4 1.5 1 0 0 1 1 1 0 Tropomyosin like bZIP_2 PF07716.15 KFY03375.1 - 1.7 8.8 4.2 6.3 7.0 0.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.7 KFY03412.1 - 5.5e-06 26.2 0.6 1.3e-05 25.0 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY03412.1 - 6.1e-05 22.8 0.4 0.00013 21.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFY03412.1 - 0.0002 21.2 0.1 0.0003 20.7 0.1 1.2 1 0 0 1 1 1 1 F-box Glyco_hydro_cc PF11790.8 KFY03441.1 - 7.9e-13 48.5 0.5 7.9e-13 48.5 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Zip PF02535.22 KFY03442.1 - 1.6e-48 165.6 5.0 2.4e-48 165.1 5.0 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter GWT1 PF06423.12 KFY03446.1 - 0.021 15.0 0.2 0.039 14.1 0.2 1.5 1 0 0 1 1 1 0 GWT1 DUF5526 PF17664.1 KFY03446.1 - 0.15 11.6 0.4 0.21 11.1 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5526) DUF3810 PF12725.7 KFY03446.1 - 0.17 11.2 1.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Cu-oxidase_2 PF07731.14 KFY03448.1 - 1.2e-34 119.0 0.5 1.8e-34 118.4 0.5 1.3 1 0 0 1 1 1 1 Multicopper oxidase HNOBA PF07701.14 KFY03461.1 - 0.03 13.8 0.2 0.039 13.4 0.2 1.1 1 0 0 1 1 1 0 Heme NO binding associated Casc1_N PF15927.5 KFY03461.1 - 3.4 7.3 18.7 0.22 11.2 13.2 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Aminotran_3 PF00202.21 KFY03462.1 - 3.7e-75 253.1 0.0 7.4e-75 252.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III P21-Arc PF04062.14 KFY03462.1 - 0.064 13.3 1.3 0.12 12.4 1.3 1.4 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit HIP1_clath_bdg PF16515.5 KFY03462.1 - 3.2 8.4 17.2 11 6.7 0.1 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 KFY03462.1 - 9.2 5.4 6.8 24 4.1 6.8 1.7 1 1 0 1 1 1 0 TMPIT-like protein Nsp1_C PF05064.13 KFY03464.1 - 0.023 14.5 4.4 0.033 14.0 4.3 1.3 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF3989 PF13150.6 KFY03464.1 - 0.28 11.0 2.2 7.6 6.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Ank_2 PF12796.7 KFY03473.1 - 1.3e-266 862.1 0.0 1.5e-15 57.6 0.0 17.2 1 1 21 22 22 22 22 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY03473.1 - 6.7e-188 606.3 6.4 3.1e-09 36.9 0.1 29.8 3 2 30 33 33 33 33 Ankyrin repeats (many copies) Ank PF00023.30 KFY03473.1 - 8e-178 570.0 0.0 0.00079 19.8 0.0 35.0 35 0 0 35 35 35 34 Ankyrin repeat Ank_3 PF13606.6 KFY03473.1 - 2.6e-169 528.1 0.0 0.0021 18.4 0.0 35.0 35 0 0 35 35 35 33 Ankyrin repeat Ank_4 PF13637.6 KFY03473.1 - 8.4e-156 504.5 0.1 6.6e-08 33.0 0.0 26.3 2 2 29 32 32 32 32 Ankyrin repeats (many copies) DUF2384 PF09722.10 KFY03473.1 - 3.2e-07 30.3 17.0 1.8e+02 2.2 0.0 16.5 20 0 0 20 20 20 0 Protein of unknown function (DUF2384) DndE PF08870.11 KFY03473.1 - 7.4e-06 26.2 0.0 6.8 7.0 0.0 6.9 5 2 1 7 7 7 1 DNA sulphur modification protein DndE PALP PF00291.25 KFY03473.1 - 1.9e-05 24.3 0.0 1.8e+02 1.3 0.0 9.7 8 2 5 13 13 13 0 Pyridoxal-phosphate dependent enzyme Shigella_OspC PF06128.11 KFY03473.1 - 3.5e-05 23.7 0.0 1.2e+02 2.3 0.0 10.0 7 5 10 17 17 17 0 Shigella flexneri OspC protein WXG100 PF06013.12 KFY03475.1 - 0.13 12.5 2.1 0.28 11.4 2.1 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF2203 PF09969.9 KFY03475.1 - 2.2 9.0 5.0 5.7 7.7 5.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SRF-TF PF00319.18 KFY03477.1 - 1.6e-07 30.7 1.3 2.1e-07 30.3 0.1 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ferric_reduct PF01794.19 KFY03478.1 - 1e-11 45.0 10.0 1e-11 45.0 10.0 2.9 4 1 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY03478.1 - 4.3e-05 23.5 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4112 PF13430.6 KFY03478.1 - 0.064 13.5 2.1 5.1 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DUF745 PF05335.13 KFY03479.1 - 0.0075 16.0 1.3 3.2 7.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF745) bZIP_1 PF00170.21 KFY03479.1 - 0.027 14.6 0.3 0.11 12.6 0.3 2.0 1 0 0 1 1 1 0 bZIP transcription factor OEP PF02321.18 KFY03479.1 - 0.28 11.0 2.7 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein TMF_TATA_bd PF12325.8 KFY03479.1 - 1.9 8.7 7.8 3.8 7.7 2.0 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SF-assemblin PF06705.11 KFY03480.1 - 0.0047 16.3 0.3 0.008 15.6 0.2 1.4 2 0 0 2 2 2 1 SF-assemblin/beta giardin FAD-SLDH PF12318.8 KFY03480.1 - 0.0053 16.8 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase CENP-F_leu_zip PF10473.9 KFY03480.1 - 0.009 16.0 0.8 0.009 16.0 0.8 1.8 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 KFY03480.1 - 0.0096 15.8 1.4 0.038 13.9 0.1 2.2 2 1 0 2 2 2 1 Sec34-like family DUF4795 PF16043.5 KFY03480.1 - 0.023 14.3 0.4 0.034 13.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Tektin PF03148.14 KFY03480.1 - 0.027 13.3 0.1 0.038 12.7 0.1 1.3 1 0 0 1 1 1 0 Tektin family PTRF_SDPR PF15237.6 KFY03480.1 - 0.039 13.6 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 PTRF/SDPR family KAR9 PF08580.10 KFY03480.1 - 0.073 11.6 0.1 0.073 11.6 0.1 1.9 1 1 1 2 2 2 0 Yeast cortical protein KAR9 Peptidase_C48 PF02902.19 KFY03481.1 - 1.7e-05 24.7 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AT_hook PF02178.19 KFY03481.1 - 1 9.4 7.3 2.8 8.1 7.3 1.8 1 0 0 1 1 1 0 AT hook motif DUF3723 PF12520.8 KFY03482.1 - 1.5e-82 277.9 3.5 4.5e-58 197.2 1.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) BTB PF00651.31 KFY03482.1 - 5.5e-14 52.3 0.1 1.4e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 KFY03483.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03483.1 - 9.9e-05 21.7 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Herpes_UL87 PF03043.14 KFY03483.1 - 0.14 10.6 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Chorismate_synt PF01264.21 KFY03501.1 - 2.5e-31 108.6 0.1 3.2e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Chorismate synthase COX7C PF02935.16 KFY03502.1 - 2.9e-24 85.1 3.3 4.9e-24 84.4 3.3 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 KFY03503.1 - 8e-91 304.7 1.2 9.3e-91 304.5 0.0 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 KFY03503.1 - 2.4e-52 176.9 1.4 5.8e-52 175.7 0.7 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KFY03503.1 - 1.6e-18 67.1 0.0 4.3e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY03503.1 - 9.6e-06 25.9 0.0 5.7e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY03503.1 - 3.6e-05 23.8 0.0 0.00013 22.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KFY03503.1 - 0.0047 16.0 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KFY03503.1 - 0.05 13.9 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Prp19 PF08606.11 KFY03503.1 - 0.07 13.1 0.3 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like Pox_Ag35 PF03286.14 KFY03503.1 - 6.5 6.5 12.9 19 5.0 12.9 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CRAL_TRIO PF00650.20 KFY03504.1 - 6.3e-11 42.3 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFY03504.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DNA_binding_1 PF01035.20 KFY03505.1 - 8.4e-28 96.3 0.2 1.8e-27 95.3 0.2 1.7 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ALG11_N PF15924.5 KFY03506.1 - 1.6e-83 279.8 0.1 2.3e-83 279.4 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFY03506.1 - 8.5e-23 80.8 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFY03506.1 - 2.8e-12 47.2 0.0 1.1e-11 45.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFY03506.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Phage_P2_GpE PF06528.12 KFY03506.1 - 0.23 11.0 2.9 3.1 7.4 0.5 2.4 2 0 0 2 2 2 0 Phage P2 GpE DUF5379 PF17350.2 KFY03506.1 - 0.56 10.5 4.5 0.3 11.4 1.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5379) ATP-synt_Z PF16594.5 KFY03506.1 - 0.87 9.1 4.0 2.7 7.6 4.0 1.9 1 1 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated 60KD_IMP PF02096.20 KFY03507.1 - 5.2e-10 39.5 0.0 7.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Pkinase PF00069.25 KFY03508.1 - 3.3e-53 180.8 0.0 7.4e-35 120.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03508.1 - 1.7e-22 80.0 0.0 1.3e-20 73.8 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFY03508.1 - 0.00026 21.0 0.0 0.003 17.5 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFY03508.1 - 0.00078 18.8 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFY03508.1 - 0.0022 16.9 0.0 0.0066 15.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RhgB_N PF09284.10 KFY03509.1 - 4.6e-106 354.0 5.7 7.1e-106 353.3 5.7 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KFY03509.1 - 3.1e-44 150.8 0.1 9.2e-44 149.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KFY03509.1 - 1.7e-21 75.8 4.0 1.7e-21 75.8 4.0 3.0 3 1 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KFY03509.1 - 3.2e-05 24.1 1.9 3.2e-05 24.1 1.9 3.9 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KFY03509.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Questin_oxidase PF14027.6 KFY03510.1 - 1.4e-95 320.7 1.9 1.7e-95 320.5 1.9 1.1 1 0 0 1 1 1 1 Questin oxidase-like EST1 PF10374.9 KFY03510.1 - 0.16 12.6 0.1 0.29 11.8 0.1 1.5 1 1 0 1 1 1 0 Telomerase activating protein Est1 RSN1_7TM PF02714.15 KFY03511.1 - 7.4e-78 261.6 15.3 7.4e-78 261.6 15.3 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFY03511.1 - 7.1e-41 139.6 1.5 7.1e-41 139.6 1.5 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFY03511.1 - 2.9e-23 83.0 0.0 3.3e-22 79.5 0.0 2.1 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFY03511.1 - 1e-21 76.9 0.2 2.3e-21 75.8 0.2 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KFY03511.1 - 0.093 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC50_N PF15295.6 KFY03511.1 - 0.17 12.1 0.5 0.27 11.4 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Dioxygenase_C PF00775.21 KFY03512.1 - 5.5e-46 156.3 0.0 7.2e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KFY03512.1 - 9.8e-28 95.8 0.0 1.5e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KFY03512.1 - 0.00038 20.7 0.0 0.005 17.1 0.0 2.5 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KFY03512.1 - 0.0013 19.0 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 Prealbumin-like fold domain SdrD_B PF17210.3 KFY03512.1 - 0.09 13.0 0.1 0.63 10.3 0.0 2.1 1 1 1 2 2 2 0 SdrD B-like domain Chlorophyllase2 PF12740.7 KFY03513.1 - 3.2e-05 23.0 0.0 4.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFY03513.1 - 0.00027 20.1 0.1 0.00044 19.4 0.1 1.3 1 1 0 1 1 1 1 Chlorophyllase adh_short_C2 PF13561.6 KFY03514.1 - 8.1e-55 185.9 0.0 9.4e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY03514.1 - 3.8e-45 153.8 0.4 4.8e-45 153.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY03514.1 - 1.7e-12 47.6 0.2 2.4e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KFY03514.1 - 9.2e-05 22.4 0.1 0.00016 21.7 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KFY03514.1 - 0.047 13.6 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFY03514.1 - 0.16 12.1 0.9 0.22 11.6 0.9 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Zn_clus PF00172.18 KFY03515.1 - 8.2e-05 22.7 7.9 0.00019 21.5 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phospholip_B PF04916.13 KFY03515.1 - 0.05 12.2 0.1 0.08 11.5 0.1 1.2 1 0 0 1 1 1 0 Phospholipase B NCD3G PF07562.14 KFY03515.1 - 0.2 11.7 2.2 0.39 10.7 2.2 1.4 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR ketoacyl-synt PF00109.26 KFY03516.1 - 1.6e-73 247.4 0.0 1.4e-72 244.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KFY03516.1 - 5.3e-73 246.0 0.0 7.5e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFY03516.1 - 4.5e-59 200.3 0.1 7.5e-59 199.6 0.1 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KFY03516.1 - 7.8e-59 199.3 0.0 1.3e-58 198.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFY03516.1 - 7.8e-50 169.3 0.1 1.9e-49 168.0 0.1 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KFY03516.1 - 5.2e-45 154.3 0.0 9.9e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY03516.1 - 4.4e-29 100.9 0.0 9.7e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFY03516.1 - 7.1e-22 78.0 0.0 3e-21 76.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.12 KFY03516.1 - 1.1e-21 77.2 0.0 4.7e-20 71.9 0.0 3.0 2 1 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KFY03516.1 - 7.3e-16 58.3 1.4 5.3e-07 29.9 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFY03516.1 - 1.3e-14 54.6 0.0 3.6e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFY03516.1 - 1.7e-14 54.3 0.0 5.8e-14 52.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03516.1 - 1.6e-13 50.7 0.0 3.8e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY03516.1 - 2.3e-13 50.6 0.0 8.8e-13 48.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY03516.1 - 5.1e-13 49.2 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY03516.1 - 9.6e-07 28.4 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.25 KFY03516.1 - 7.6e-06 25.5 0.1 2.8e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.9 KFY03516.1 - 9.3e-06 25.5 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase adh_short_C2 PF13561.6 KFY03516.1 - 1e-05 25.2 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFY03516.1 - 0.00016 21.2 0.0 0.00072 19.1 0.0 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family DREV PF05219.12 KFY03516.1 - 0.00056 19.1 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Thiolase_N PF00108.23 KFY03516.1 - 0.00093 18.6 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.20 KFY03516.1 - 0.0011 18.1 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase AMP-binding_C PF13193.6 KFY03516.1 - 0.0073 17.3 0.0 0.025 15.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_33 PF10017.9 KFY03516.1 - 0.0096 15.1 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent 3Beta_HSD PF01073.19 KFY03516.1 - 0.025 13.6 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MTS PF05175.14 KFY03516.1 - 0.037 13.6 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain SAT PF16073.5 KFY03516.1 - 0.079 12.7 2.7 0.36 10.5 2.5 2.2 2 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_zinc_N PF00107.26 KFY03517.1 - 5.8e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY03517.1 - 0.00057 19.7 0.9 0.0023 17.8 0.1 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 KFY03518.1 - 2.2e-39 135.5 0.0 2.7e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.8 KFY03519.1 - 0.0022 18.2 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3919 PF13057.6 KFY03519.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Myb_DNA-bind_6 PF13921.6 KFY03527.1 - 3e-05 24.2 0.5 5.3e-05 23.4 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFY03527.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3388 PF11868.8 KFY03527.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Pkinase PF00069.25 KFY03528.1 - 4.5e-13 49.2 0.0 1.8e-11 43.9 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03528.1 - 0.00036 19.9 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Helicase_C PF00271.31 KFY03551.1 - 4e-10 40.0 0.0 8.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MoCF_biosynth PF00994.24 KFY03551.1 - 0.00023 20.8 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain RecQ_Zn_bind PF16124.5 KFY03551.1 - 0.045 14.5 0.1 0.13 13.0 0.1 1.8 1 0 0 1 1 1 0 RecQ zinc-binding F-box-like PF12937.7 KFY03552.1 - 0.00039 20.3 1.1 0.00066 19.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY03552.1 - 0.0031 17.3 0.1 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain DUF3663 PF12404.8 KFY03552.1 - 0.14 12.3 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Peptidase USP7_C2 PF14533.6 KFY03555.1 - 0.038 13.7 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF489 PF04356.12 KFY03555.1 - 0.11 12.6 0.4 0.25 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF489) MetOD1 PF18546.1 KFY03556.1 - 0.24 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Metanogen output domain 1 Pkinase PF00069.25 KFY03557.1 - 3.7e-35 121.6 0.0 5.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03557.1 - 6.4e-21 74.8 0.0 8.8e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFY03557.1 - 2.7e-07 30.1 0.1 4.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFY03557.1 - 3.3e-05 23.4 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 KFY03557.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-MYND PF01753.18 KFY03562.1 - 3.6e-09 36.5 9.9 6e-09 35.9 9.9 1.4 1 0 0 1 1 1 1 MYND finger Ald_Xan_dh_C PF01315.22 KFY03562.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain zf-HIT PF04438.16 KFY03562.1 - 0.29 11.0 7.9 0.53 10.2 7.9 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KFY03562.1 - 0.72 10.2 7.0 1.4 9.3 7.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pheromone PF08015.11 KFY03568.1 - 0.06 14.4 0.3 0.087 13.9 0.3 1.4 1 1 0 1 1 1 0 Fungal mating-type pheromone E1-E2_ATPase PF00122.20 KFY03576.1 - 1.5e-41 141.9 4.9 1.5e-41 141.9 4.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 KFY03576.1 - 2.2e-05 24.8 0.1 8.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF4519 PF15012.6 KFY03576.1 - 3.8 7.8 4.2 1 9.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Nramp PF01566.18 KFY03578.1 - 1.5e-87 293.9 17.1 1.5e-87 293.9 17.1 1.8 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein HMA PF00403.26 KFY03579.1 - 4.9e-24 84.6 0.2 5.3e-12 46.0 0.0 4.0 3 0 0 3 3 3 3 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 KFY03579.1 - 1.4e-20 73.6 0.2 6.5e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase PI3K_P85_iSH2 PF16454.5 KFY03580.1 - 0.016 14.8 2.6 0.024 14.2 1.3 1.8 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Presenilin PF01080.17 KFY03583.1 - 5.6 5.6 4.9 5.8 5.6 4.9 1.2 1 0 0 1 1 1 0 Presenilin IFT57 PF10498.9 KFY03584.1 - 0.028 13.4 1.8 0.032 13.2 1.8 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TACC_C PF05010.14 KFY03584.1 - 0.03 14.1 1.9 0.036 13.9 1.9 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NUDE_C PF04880.13 KFY03584.1 - 0.06 13.8 1.4 0.078 13.5 1.4 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF1664 PF07889.12 KFY03584.1 - 0.075 13.1 0.7 0.09 12.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Pox_Rap94 PF03294.14 KFY03584.1 - 0.11 10.6 0.0 0.1 10.7 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 APH PF01636.23 KFY03592.1 - 1e-11 45.2 0.0 1.6e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY03592.1 - 5.8e-06 26.0 0.1 1.6e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFY03592.1 - 0.016 14.6 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Fructosamin_kin PF03881.14 KFY03592.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Vac14_Fig4_bd PF11916.8 KFY03593.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding DUF3435 PF11917.8 KFY03611.1 - 4.3e-47 161.0 0.1 5.1e-47 160.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Lebercilin PF15619.6 KFY03611.1 - 0.47 10.1 4.1 1.6 8.3 0.9 2.4 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_C48 PF02902.19 KFY03625.1 - 3.6e-12 46.6 0.1 3.4e-11 43.4 0.1 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 KFY03628.1 - 8.6e-09 35.5 0.0 8.8e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pyr_redox_2 PF07992.14 KFY03634.1 - 3.3e-46 157.9 0.6 3.9e-46 157.6 0.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY03634.1 - 1.8e-17 63.6 1.5 3.5e-15 56.3 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY03634.1 - 1.6e-16 60.4 0.7 9.5e-15 54.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY03634.1 - 1.6e-05 25.0 0.3 0.013 15.7 0.1 2.9 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KFY03634.1 - 3e-05 24.4 0.1 0.0056 17.1 0.0 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KFY03634.1 - 0.00019 20.8 0.1 0.00079 18.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KFY03634.1 - 0.013 14.6 3.5 1.2 8.1 0.3 3.3 3 1 0 4 4 4 0 Glucose inhibited division protein A DAO PF01266.24 KFY03634.1 - 0.016 14.8 0.1 1.7 8.1 0.1 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFY03634.1 - 0.018 14.2 0.0 0.27 10.3 0.0 2.7 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFY03634.1 - 0.018 14.3 2.1 2.2 7.4 0.1 3.0 2 1 1 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 KFY03634.1 - 0.045 12.6 0.0 0.45 9.3 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 KFY03634.1 - 0.047 12.4 0.2 0.54 8.9 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KFY03634.1 - 0.05 12.7 4.9 0.14 11.3 0.2 2.9 2 1 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 KFY03634.1 - 0.073 12.4 0.4 0.32 10.3 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Attacin_N PF03768.15 KFY03634.1 - 0.085 13.0 0.6 0.4 10.8 0.1 2.3 1 1 1 2 2 2 0 Attacin, N-terminal region APH PF01636.23 KFY03638.1 - 2.2e-07 31.1 0.1 1e-06 28.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY03638.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ank_2 PF12796.7 KFY03638.1 - 0.012 16.2 0.0 0.044 14.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY03638.1 - 0.015 15.9 0.0 0.047 14.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Pkinase PF00069.25 KFY03638.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Amidase PF01425.21 KFY03639.1 - 6.1e-71 239.7 0.8 1.6e-65 221.8 0.1 2.1 2 0 0 2 2 2 2 Amidase SesA PF17107.5 KFY03640.1 - 1.1e-24 87.0 1.1 3e-24 85.5 1.1 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 KFY03640.1 - 8.5e-20 71.1 3.7 2.3e-09 37.7 0.1 3.4 3 1 0 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY03640.1 - 2.5e-17 63.0 1.2 2.4e-05 24.8 0.1 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFY03640.1 - 3.4e-14 52.6 8.5 0.001 19.4 0.2 6.1 6 0 0 6 6 5 4 Ankyrin repeat Ank_3 PF13606.6 KFY03640.1 - 5.1e-10 38.7 0.4 0.16 12.6 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.12 KFY03640.1 - 3.2e-09 36.9 0.1 5.2e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KFY03640.1 - 4.6e-08 33.2 0.6 0.00083 19.6 0.1 2.9 3 0 0 3 3 2 2 Ankyrin repeats (many copies) NB-ARC PF00931.22 KFY03640.1 - 0.0018 17.5 0.0 0.0079 15.4 0.0 1.9 1 1 1 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KFY03640.1 - 0.023 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFY03640.1 - 0.038 14.4 0.0 0.097 13.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFY03640.1 - 0.06 13.4 0.0 0.95 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFY03640.1 - 0.069 13.5 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFY03640.1 - 0.11 12.9 0.1 0.58 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain TbpB_B_D PF01298.18 KFY03640.1 - 0.39 11.1 7.1 17 5.8 0.5 3.6 1 1 2 3 3 3 0 C-lobe and N-lobe beta barrels of Tf-binding protein B NAD_binding_6 PF08030.12 KFY03642.1 - 5.7e-11 42.8 0.0 3.3e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFY03642.1 - 2.4e-07 30.9 7.4 2.4e-07 30.9 7.4 2.8 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY03642.1 - 4.7e-07 29.9 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain F-box PF00646.33 KFY03642.1 - 0.00039 20.2 0.2 0.0012 18.6 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY03642.1 - 0.016 15.1 1.9 0.028 14.3 0.1 2.5 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 KFY03642.1 - 0.02 14.8 0.0 0.061 13.2 0.0 1.9 1 0 0 1 1 1 0 F-box HECT PF00632.25 KFY03671.1 - 1.3e-93 313.9 0.0 1.8e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFY03671.1 - 2.8e-32 110.5 19.0 1.5e-10 40.9 0.9 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFY03671.1 - 2.7e-18 66.1 0.0 7.3e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Lipase_GDSL_2 PF13472.6 KFY03672.1 - 5.7e-16 59.4 0.1 9.5e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY03672.1 - 2.5e-10 40.7 0.0 4.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFY03672.1 - 0.046 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family APS-reductase_C PF12139.8 KFY03678.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Alpha-amylase PF00128.24 KFY03688.1 - 6.6e-20 71.9 3.5 2.2e-16 60.4 0.9 3.4 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KFY03688.1 - 2.2e-13 50.5 0.0 3.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFY03688.1 - 3e-05 23.6 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFY03688.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Corona_nucleoca PF00937.18 KFY03688.1 - 0.51 9.3 9.9 0.95 8.4 9.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FA_desaturase PF00487.24 KFY03688.1 - 5.9 6.6 21.4 0.75 9.6 1.0 3.0 2 0 0 2 2 2 0 Fatty acid desaturase Polysacc_deac_1 PF01522.21 KFY03689.1 - 3.3e-22 78.7 0.0 6.4e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase NmrA PF05368.13 KFY03689.1 - 6.1e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFY03689.1 - 6.7e-05 22.5 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFY03689.1 - 0.002 17.2 0.4 0.028 13.4 0.4 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFY03689.1 - 0.0072 16.8 0.8 0.019 15.4 0.0 2.1 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFY03689.1 - 0.017 14.3 0.1 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein AMP-binding PF00501.28 KFY03690.1 - 1.7e-92 310.2 0.0 2.2e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY03690.1 - 5.3e-12 46.5 0.6 3.8e-11 43.8 0.9 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PgaD PF13994.6 KFY03691.1 - 0.054 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein HAND PF09110.11 KFY03706.1 - 0.039 14.7 4.7 0.042 14.6 4.7 1.2 1 0 0 1 1 1 0 HAND MinE PF03776.14 KFY03706.1 - 0.076 13.0 0.2 0.096 12.7 0.2 1.2 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF3350 PF11830.8 KFY03716.1 - 0.039 14.3 3.1 1.7 9.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3350) Paramyxo_ncap PF00973.19 KFY03716.1 - 0.073 12.0 0.9 0.072 12.0 0.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Jak1_Phl PF17887.1 KFY03716.1 - 0.66 9.9 3.9 0.93 9.5 3.9 1.4 1 1 0 1 1 1 0 Jak1 pleckstrin homology-like domain Hydrolase PF00702.26 KFY03735.1 - 1.1e-14 55.2 0.0 1.5e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFY03735.1 - 0.00082 19.2 0.3 0.06 13.1 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFY03735.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFY03735.1 - 0.023 14.8 0.1 0.29 11.2 0.1 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IL1 PF00340.19 KFY03735.1 - 0.19 11.4 0.2 0.27 10.9 0.2 1.2 1 0 0 1 1 1 0 Interleukin-1 / 18 CENP-B_N PF04218.13 KFY03735.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain E1-E2_ATPase PF00122.20 KFY03755.1 - 3.1e-15 56.2 0.0 3.1e-15 56.2 0.0 1.9 2 1 1 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFY03755.1 - 2.9e-12 46.1 0.5 6.9e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF4731 PF15875.5 KFY03756.1 - 0.81 9.9 2.2 1 9.6 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) CDC45 PF02724.14 KFY03756.1 - 2.5 6.3 10.6 5.1 5.3 10.6 1.6 1 0 0 1 1 1 0 CDC45-like protein FeS PF04060.13 KFY03769.1 - 6.9e-07 28.8 30.1 41 4.0 0.0 11.6 11 1 0 11 11 11 10 Putative Fe-S cluster RSN1_7TM PF02714.15 KFY03784.1 - 3.9e-16 59.2 6.4 3.9e-16 59.2 6.4 1.4 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KFY03784.1 - 3e-14 53.0 0.0 4.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter FAD_binding_8 PF08022.12 KFY03785.1 - 6.2e-10 39.1 0.1 1.5e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFY03785.1 - 7.7e-08 32.6 0.0 2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain SesA PF17107.5 KFY03785.1 - 9.5e-08 32.3 0.3 2.3e-07 31.0 0.2 1.5 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KFY03785.1 - 0.00057 20.0 34.7 0.025 14.7 3.6 3.4 2 1 0 2 2 2 2 Sigma domain on NACHT-NTPases CorA PF01544.18 KFY03829.1 - 9.2e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VKOR PF07884.14 KFY03829.1 - 0.03 14.5 1.0 0.08 13.1 1.0 1.7 1 1 0 1 1 1 0 Vitamin K epoxide reductase family Ank_2 PF12796.7 KFY03830.1 - 7.1e-81 266.9 41.5 9.9e-14 51.7 0.3 9.2 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY03830.1 - 1e-66 220.5 10.0 6.4e-08 33.0 0.0 15.9 1 1 16 17 17 17 15 Ankyrin repeats (many copies) Ank PF00023.30 KFY03830.1 - 3.3e-61 201.2 27.0 0.00047 20.5 0.0 19.3 19 0 0 19 19 19 15 Ankyrin repeat Ank_3 PF13606.6 KFY03830.1 - 1e-48 157.6 9.6 0.011 16.1 0.0 18.8 18 0 0 18 18 18 11 Ankyrin repeat Ank_5 PF13857.6 KFY03830.1 - 2.6e-29 100.9 17.9 0.0011 19.2 0.0 12.6 7 4 5 13 13 13 7 Ankyrin repeats (many copies) NACHT_N PF17100.5 KFY03830.1 - 2.4e-25 89.7 0.3 5.2e-25 88.6 0.3 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KFY03830.1 - 4.4e-11 43.0 0.0 1.4e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFY03830.1 - 0.00016 22.1 0.0 0.0036 17.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KFY03830.1 - 0.0052 17.1 0.0 0.24 11.8 0.0 3.0 3 0 0 3 3 3 1 RNA helicase KAP_NTPase PF07693.14 KFY03830.1 - 0.024 13.9 0.0 0.15 11.3 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KFY03830.1 - 0.029 14.6 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFY03830.1 - 0.031 14.4 0.0 1.8 8.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFY03830.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFY03830.1 - 0.088 12.0 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Arg_repressor PF01316.21 KFY03830.1 - 5.1 6.9 12.7 23 4.8 0.0 6.4 8 0 0 8 8 6 0 Arginine repressor, DNA binding domain NPV_P10 PF05531.12 KFY03831.1 - 0.0046 17.4 0.0 0.0077 16.7 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KFY03831.1 - 0.01 16.2 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 KFY03831.1 - 0.011 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II HsbA PF12296.8 KFY03831.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Spc7 PF08317.11 KFY03831.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KFY03831.1 - 0.22 12.0 0.2 0.78 10.2 0.1 1.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2076 PF09849.9 KFY03832.1 - 9 6.3 6.8 9 6.3 6.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ABC_tran_CTD PF16326.5 KFY03838.1 - 0.0085 16.3 4.8 0.018 15.3 4.8 1.5 1 0 0 1 1 1 1 ABC transporter C-terminal domain ADIP PF11559.8 KFY03838.1 - 0.0086 16.2 0.9 0.013 15.6 0.9 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 KFY03838.1 - 0.016 15.6 3.0 0.026 14.9 3.0 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region GPS2_interact PF15784.5 KFY03838.1 - 0.059 13.8 1.3 0.12 12.8 1.3 1.5 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain STAG PF08514.11 KFY03838.1 - 0.062 13.2 1.0 0.12 12.3 0.6 1.6 2 0 0 2 2 2 0 STAG domain DUF1704 PF08014.11 KFY03838.1 - 0.09 11.8 1.5 0.87 8.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1704) DUF1515 PF07439.11 KFY03838.1 - 0.21 11.7 0.3 0.44 10.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DivIC PF04977.15 KFY03838.1 - 0.27 11.0 3.1 0.5 10.2 3.1 1.4 1 0 0 1 1 1 0 Septum formation initiator SDA1 PF05285.12 KFY03840.1 - 2.4 7.5 19.4 3.8 6.8 19.4 1.3 1 0 0 1 1 1 0 SDA1 RNase_H PF00075.24 KFY03842.1 - 2.1e-08 34.4 0.6 5.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 RNase H DUF935 PF06074.12 KFY03842.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DDE_3 PF13358.6 KFY03844.1 - 8.6e-13 48.3 0.5 1.7e-12 47.3 0.5 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFY03844.1 - 6e-07 29.6 0.1 3.4e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.10 KFY03844.1 - 0.00099 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 KFY03844.1 - 0.0016 18.1 0.2 0.0059 16.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 KFY03844.1 - 0.016 15.0 0.0 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 KFY03844.1 - 0.02 15.3 0.3 0.045 14.2 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_38 PF13936.6 KFY03844.1 - 0.028 14.2 0.2 0.37 10.6 0.3 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 KFY03844.1 - 0.066 12.8 0.0 0.22 11.1 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding zf-RING_UBOX PF13445.6 KFY03844.1 - 0.071 13.1 0.2 0.23 11.5 0.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFY03844.1 - 0.14 12.0 0.8 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sigma70_r4 PF04545.16 KFY03844.1 - 0.17 11.4 2.8 0.22 11.1 0.1 2.4 3 0 0 3 3 2 0 Sigma-70, region 4 zf-C3HC4_2 PF13923.6 KFY03844.1 - 0.21 11.4 0.6 0.62 10.0 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 KFY03844.1 - 0.41 10.7 2.4 0.61 10.1 0.4 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain MerR PF00376.23 KFY03844.1 - 0.62 9.9 6.1 1.1 9.1 0.1 3.8 5 0 0 5 5 5 0 MerR family regulatory protein 4HBT PF03061.22 KFY03866.1 - 8.6e-07 29.2 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily SUR7 PF06687.12 KFY03867.1 - 4.3e-28 98.4 16.0 5.4e-28 98.1 16.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2236 PF09995.9 KFY03869.1 - 5.1e-35 121.7 0.0 6.2e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) YscJ_FliF PF01514.17 KFY03869.1 - 0.056 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family DUF4715 PF15835.5 KFY03872.1 - 0.014 15.5 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) MFS_1 PF07690.16 KFY03873.1 - 8.3e-42 143.4 58.5 8.3e-31 107.2 33.8 3.4 2 2 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY03873.1 - 1.1e-13 50.5 25.9 2.3e-13 49.5 25.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFY03873.1 - 9.3e-12 44.5 22.9 1.5e-11 43.9 9.8 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter UPF0060 PF02694.15 KFY03893.1 - 0.00013 22.1 1.8 0.00021 21.5 1.8 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family TcpE PF12648.7 KFY03893.1 - 0.12 12.9 1.9 0.2 12.2 1.9 1.4 1 0 0 1 1 1 0 TcpE family Arteri_Gl PF00951.18 KFY03893.1 - 1 9.2 7.3 1.6 8.5 7.3 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein DUF5014 PF16406.5 KFY03894.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5014) Pkinase PF00069.25 KFY03895.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NPV_P10 PF05531.12 KFY03895.1 - 0.081 13.4 1.0 0.19 12.2 1.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein HTH_35 PF13693.6 KFY03895.1 - 0.098 12.7 0.4 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TFIIA PF03153.13 KFY03895.1 - 7.5 6.4 14.5 10 6.0 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Golgin_A5 PF09787.9 KFY03896.1 - 0.00034 20.2 1.8 0.00045 19.8 1.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Tektin PF03148.14 KFY03896.1 - 0.0026 16.6 1.1 0.0034 16.2 1.1 1.1 1 0 0 1 1 1 1 Tektin family Tup_N PF08581.10 KFY03896.1 - 0.0035 17.6 1.7 0.011 16.1 0.1 2.1 1 1 1 2 2 2 1 Tup N-terminal DUF641 PF04859.12 KFY03896.1 - 0.0077 16.6 2.4 0.012 15.9 2.0 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.9 KFY03896.1 - 0.0087 16.3 3.9 0.012 15.8 3.9 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 LRRFIP PF09738.9 KFY03896.1 - 0.0093 15.5 0.4 0.013 15.0 0.4 1.1 1 0 0 1 1 1 1 LRRFIP family TMCO5 PF14992.6 KFY03896.1 - 0.01 15.4 1.4 0.015 14.9 1.4 1.2 1 0 0 1 1 1 0 TMCO5 family ATG16 PF08614.11 KFY03896.1 - 0.011 16.0 2.6 0.019 15.2 2.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.21 KFY03896.1 - 0.017 14.7 3.0 0.024 14.2 3.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein MAD PF05557.13 KFY03896.1 - 0.017 13.5 1.7 0.022 13.2 1.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 KFY03896.1 - 0.018 14.0 1.1 0.028 13.3 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PhoU PF01895.19 KFY03896.1 - 0.022 15.2 0.1 0.038 14.5 0.1 1.4 1 0 0 1 1 1 0 PhoU domain Fzo_mitofusin PF04799.13 KFY03896.1 - 0.022 14.3 0.4 0.034 13.7 0.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region CortBP2 PF09727.9 KFY03896.1 - 0.026 14.5 1.5 0.035 14.0 1.5 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 PRKG1_interact PF15898.5 KFY03896.1 - 0.026 15.4 3.2 0.044 14.7 3.2 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SOGA PF11365.8 KFY03896.1 - 0.027 15.6 1.0 0.047 14.8 1.0 1.4 1 0 0 1 1 1 0 Protein SOGA DUF3584 PF12128.8 KFY03896.1 - 0.028 11.9 2.0 0.033 11.7 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CLZ PF16526.5 KFY03896.1 - 0.029 14.7 1.1 0.22 11.9 0.1 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4515 PF14988.6 KFY03896.1 - 0.03 14.2 2.0 0.042 13.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) FapA PF03961.13 KFY03896.1 - 0.033 12.8 0.6 0.043 12.4 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HMMR_N PF15905.5 KFY03896.1 - 0.041 13.4 2.0 0.055 12.9 2.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 KFY03896.1 - 0.041 14.2 0.7 0.079 13.3 0.7 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 KFY03896.1 - 0.053 13.6 1.5 0.13 12.4 0.3 2.0 2 0 0 2 2 2 0 bZIP transcription factor DUF3450 PF11932.8 KFY03896.1 - 0.068 12.5 2.4 0.12 11.7 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 KFY03896.1 - 0.07 13.8 4.3 1.5 9.5 0.6 3.0 1 1 2 3 3 3 0 SlyX DUF2383 PF09537.10 KFY03896.1 - 0.07 13.5 0.6 0.15 12.4 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) TMF_TATA_bd PF12325.8 KFY03896.1 - 0.075 13.3 4.8 0.13 12.5 3.6 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spectrin PF00435.21 KFY03896.1 - 0.086 13.3 1.8 4.7 7.7 0.9 2.2 1 1 1 2 2 2 0 Spectrin repeat MbeD_MobD PF04899.12 KFY03896.1 - 0.095 12.8 0.1 0.26 11.4 0.1 1.7 1 1 0 1 1 1 0 MbeD/MobD like SKA2 PF16740.5 KFY03896.1 - 0.13 12.1 1.1 0.2 11.4 1.1 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 KFY03896.1 - 0.16 11.8 5.8 0.1 12.4 3.4 1.9 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 KFY03896.1 - 0.19 12.3 5.4 1.1 9.8 5.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KFY03896.1 - 0.39 11.2 6.4 0.53 10.8 4.7 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 KFY03896.1 - 0.46 10.8 4.3 1.3 9.4 2.2 2.5 1 1 2 3 3 3 0 Csm1 N-terminal domain Prefoldin_2 PF01920.20 KFY03896.1 - 0.91 9.5 5.2 6.7 6.7 2.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit WXG100 PF06013.12 KFY03897.1 - 0.027 14.7 0.0 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ZapB PF06005.12 KFY03897.1 - 0.036 14.5 1.1 5.6 7.5 0.0 2.5 2 1 0 2 2 2 0 Cell division protein ZapB SNARE PF05739.19 KFY03897.1 - 0.047 13.7 0.6 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 SNARE domain Syntaxin PF00804.25 KFY03897.1 - 0.062 13.0 0.1 1.6 8.4 0.0 2.1 2 0 0 2 2 2 0 Syntaxin NOG1_N PF17835.1 KFY03897.1 - 0.08 12.9 0.9 0.12 12.4 0.9 1.2 1 0 0 1 1 1 0 NOG1 N-terminal helical domain PhaP_Bmeg PF09602.10 KFY03897.1 - 0.13 12.2 1.2 0.96 9.4 0.1 2.4 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) FlaC_arch PF05377.11 KFY03897.1 - 0.22 11.9 2.1 5.1 7.6 0.0 3.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Patatin PF01734.22 KFY03899.1 - 1e-19 71.5 0.2 2e-19 70.6 0.2 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.6 KFY03899.1 - 0.0018 18.2 9.4 0.0042 17.0 9.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFY03899.1 - 0.34 10.8 8.2 0.75 9.7 8.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFY03899.1 - 0.41 10.5 4.9 1.2 9.1 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFY03899.1 - 0.53 10.7 11.1 1.5 9.2 11.1 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KFY03899.1 - 1.1 9.2 9.2 2.8 7.9 9.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY03899.1 - 1.6 8.8 7.3 4.8 7.3 7.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 KFY03899.1 - 2.6 8.3 7.3 6.2 7.0 7.3 1.6 1 0 0 1 1 1 0 FYVE zinc finger RSN1_7TM PF02714.15 KFY03900.1 - 7.2e-77 258.4 25.5 7.2e-77 258.4 25.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFY03900.1 - 2.4e-43 147.6 1.1 2.4e-43 147.6 1.1 3.4 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFY03900.1 - 1e-26 94.3 3.4 4.7e-15 56.2 1.5 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFY03900.1 - 5.5e-12 45.7 0.0 2.3e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter TPR_10 PF13374.6 KFY03913.1 - 4.5e-15 55.0 0.1 1.2e-09 37.7 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03913.1 - 2.9e-09 37.1 0.0 3.2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03913.1 - 0.095 12.8 0.0 2.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 KFY03914.1 - 1.3e-56 189.2 15.6 7.6e-15 55.3 0.2 5.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY03914.1 - 4e-43 145.3 10.1 2.7e-08 34.2 0.1 6.6 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFY03914.1 - 2.8e-38 128.7 10.7 1.4e-06 28.4 0.1 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFY03914.1 - 6.6e-34 112.1 9.2 3e-06 27.1 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFY03914.1 - 1.3e-28 98.7 10.7 2.1e-07 31.1 0.3 7.1 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Transketolase_N PF00456.21 KFY03915.1 - 0.04 12.9 1.1 0.054 12.4 1.1 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DDHD PF02862.17 KFY03915.1 - 0.19 11.8 0.7 11 6.1 0.2 2.2 2 0 0 2 2 2 0 DDHD domain RSN1_7TM PF02714.15 KFY03916.1 - 2.4e-77 260.0 24.1 2.4e-77 260.0 24.1 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFY03916.1 - 7.5e-43 146.0 1.4 7.5e-43 146.0 1.4 3.7 5 1 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFY03916.1 - 3.4e-29 102.3 3.4 1.7e-17 64.2 0.6 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFY03916.1 - 7.4e-12 45.3 0.0 2.9e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF2180 PF09947.9 KFY03916.1 - 0.19 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Helicase_C PF00271.31 KFY03918.1 - 2.9e-06 27.6 0.0 2.6e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFY03918.1 - 0.0058 16.4 0.3 0.01 15.6 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Integrin_b_cyt PF08725.11 KFY03918.1 - 0.13 11.9 0.2 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Integrin beta cytoplasmic domain Rad50_zn_hook PF04423.14 KFY03918.1 - 0.22 11.4 1.1 28 4.7 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF2058 PF09831.9 KFY03918.1 - 0.48 10.6 1.9 1.3 9.1 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Vac14_Fig4_bd PF11916.8 KFY03923.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fig4_bd PF11916.8 KFY03928.1 - 0.053 13.2 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Pkinase_fungal PF17667.1 KFY03929.1 - 5.6e-21 74.8 0.0 7.3e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KFY03930.1 - 3.9e-30 105.0 0.2 5.8e-30 104.4 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Microcephalin PF12258.8 KFY03930.1 - 0.052 12.8 0.3 0.052 12.8 0.3 2.4 3 0 0 3 3 3 0 Microcephalin protein F-box PF00646.33 KFY03931.1 - 4.4e-06 26.4 0.4 9.8e-06 25.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFY03931.1 - 0.0025 17.7 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 KFY03931.1 - 0.0099 15.8 0.3 0.022 14.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like Kdo PF06293.14 KFY03932.1 - 3.6e-07 29.7 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY03932.1 - 1.4e-06 28.4 0.1 0.00011 22.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KFY03932.1 - 0.00029 20.3 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KFY03932.1 - 0.00058 19.5 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KFY03932.1 - 0.0065 16.1 0.0 0.53 9.8 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.11 KFY03932.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KFY03932.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_C48 PF02902.19 KFY03939.1 - 4.3e-06 26.7 0.0 5.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BTB PF00651.31 KFY03940.1 - 1.1e-17 64.3 0.1 2.5e-17 63.1 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF3723 PF12520.8 KFY03941.1 - 9.9e-82 275.2 0.2 2e-81 274.2 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) HTH_psq PF05225.16 KFY03972.1 - 0.0016 18.1 0.8 0.0028 17.4 0.8 1.4 1 1 0 1 1 1 1 helix-turn-helix, Psq domain HTH_8 PF02954.19 KFY03972.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 KFY03972.1 - 0.046 13.9 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 KFY03972.1 - 0.086 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Gly_transf_sug PF04488.15 KFY03973.1 - 1.3e-10 41.7 0.0 3.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PIG-L PF02585.17 KFY03973.1 - 2.1e-10 41.3 0.0 3.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase rve PF00665.26 KFY03974.1 - 7.9e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFY03974.1 - 6e-07 29.5 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Trypan_PARP PF05887.11 KFY03974.1 - 0.0037 17.2 7.2 0.36 10.8 2.0 2.3 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) AF-4 PF05110.13 KFY03974.1 - 0.046 11.8 5.5 0.063 11.4 5.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CopB PF05275.11 KFY03974.1 - 0.061 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) PAD_porph PF04371.15 KFY03975.1 - 3.4e-108 361.7 0.0 3.8e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Helo_like_N PF17111.5 KFY03976.1 - 5.5e-61 205.6 6.2 9.3e-60 201.6 1.7 2.7 2 1 1 3 3 3 3 Fungal N-terminal domain of STAND proteins QVR PF17064.5 KFY03976.1 - 0.059 13.6 1.8 11 6.3 0.0 3.2 3 0 0 3 3 3 0 Sleepless protein SesA PF17107.5 KFY03976.1 - 0.085 13.0 0.5 2 8.6 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Toxin_2 PF00451.19 KFY03976.1 - 0.1 12.9 1.0 7.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 OTT_1508_deam PF14441.6 KFY03977.1 - 1.8e-18 66.3 0.7 4.3e-18 65.1 0.7 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box-like PF12937.7 KFY03977.1 - 0.00012 21.9 0.5 0.00034 20.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFY03977.1 - 0.00022 21.1 0.5 0.00067 19.5 0.1 2.0 2 0 0 2 2 2 1 F-box F-box PF00646.33 KFY03977.1 - 0.00041 20.1 5.7 0.0023 17.8 0.2 3.0 3 0 0 3 3 3 1 F-box domain DUF3648 PF12364.8 KFY03977.1 - 0.7 10.1 3.0 3.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) Pkinase_fungal PF17667.1 KFY03989.1 - 1.4e-40 139.4 0.0 1.1e-25 90.4 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KFY03990.1 - 6.8e-07 29.4 0.2 0.002 18.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFY03990.1 - 2e-06 27.3 0.2 6.4e-06 25.7 0.1 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFY03990.1 - 3.4e-06 26.8 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KFY03990.1 - 0.00037 20.0 0.1 0.00058 19.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KFY03990.1 - 0.0012 18.5 0.4 0.003 17.2 0.1 1.7 1 1 1 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KFY03990.1 - 0.0033 16.3 0.4 0.0071 15.2 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Nuc_sug_transp PF04142.15 KFY04007.1 - 3.8e-74 249.7 8.7 4.9e-74 249.3 8.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFY04007.1 - 9.9e-06 25.8 8.8 9.9e-06 25.8 8.8 3.1 2 1 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 KFY04007.1 - 0.0021 17.3 3.1 0.0021 17.3 3.1 2.6 2 1 0 2 2 2 1 UAA transporter family Pkinase_fungal PF17667.1 KFY04008.1 - 2e-81 273.9 0.0 3.8e-81 273.0 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFY04010.1 - 6.3e-10 39.4 0.3 2.9e-09 37.2 0.3 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY04010.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFY04010.1 - 0.015 14.6 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain DUF772 PF05598.11 KFY04018.1 - 0.074 13.1 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Transposase domain (DUF772) Dysbindin PF04440.16 KFY04024.1 - 0.037 14.2 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Epimerase PF01370.21 KFY04028.1 - 1e-12 48.0 0.1 2.6e-11 43.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY04028.1 - 1.7e-11 44.3 0.1 2.8e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFY04028.1 - 4.8e-09 36.1 1.5 9.1e-09 35.2 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KFY04028.1 - 4.2e-06 26.4 0.0 0.0013 18.2 0.1 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFY04028.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KFY04028.1 - 0.0001 21.4 0.1 0.0024 16.9 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PglD_N PF17836.1 KFY04028.1 - 0.02 15.6 0.5 0.095 13.4 0.1 2.2 2 1 0 2 2 2 0 PglD N-terminal domain Semialdhyde_dh PF01118.24 KFY04028.1 - 0.028 14.8 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFY04028.1 - 0.068 12.3 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans_2 PF11951.8 KFY04029.1 - 2.1e-06 26.8 0.7 3.2e-05 22.9 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFY04030.1 - 7.3e-26 90.9 46.1 4.8e-21 75.1 30.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferritin_2 PF13668.6 KFY04032.1 - 7.8e-43 145.9 3.7 7.8e-43 145.9 3.7 1.5 2 0 0 2 2 2 1 Ferritin-like domain AdoMet_dc PF02675.15 KFY04033.1 - 0.2 12.0 0.2 0.26 11.6 0.2 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase TPR_12 PF13424.6 KFY04034.1 - 8.2e-50 167.0 6.5 4.8e-20 71.6 0.3 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFY04034.1 - 2.9e-46 154.1 1.8 1.3e-14 53.5 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFY04034.1 - 2.8e-17 61.7 1.1 9.6e-05 22.0 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY04034.1 - 4.3e-15 54.5 0.5 1.9e-05 24.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY04034.1 - 5.8e-15 54.2 1.2 0.00043 20.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY04034.1 - 7.3e-14 50.8 1.2 0.00025 21.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFY04034.1 - 2.9e-12 47.0 0.1 4.1e-07 30.5 0.0 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 KFY04034.1 - 1.8e-08 34.2 2.1 0.025 14.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY04034.1 - 3.2e-08 33.3 3.0 9.5e-08 31.8 3.1 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 KFY04034.1 - 1.9e-06 27.8 0.3 1.8 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY04034.1 - 3.9e-06 27.0 0.1 0.043 14.0 0.0 3.3 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFY04034.1 - 1.2e-05 25.7 0.7 2.4 9.0 0.0 4.6 5 1 0 5 5 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFY04034.1 - 1.2e-05 25.5 0.0 2.9 8.8 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY04034.1 - 5.2e-05 23.7 2.9 0.0036 17.8 0.7 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KFY04034.1 - 0.00014 21.8 2.0 0.71 10.0 0.0 3.1 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KFY04034.1 - 0.00017 22.1 0.2 7 7.8 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFY04034.1 - 0.00028 20.5 5.9 0.049 13.3 0.1 3.6 3 0 0 3 3 3 1 TPR repeat PPR PF01535.20 KFY04034.1 - 0.0034 17.5 0.0 3.3 8.2 0.0 3.0 3 0 0 3 3 3 1 PPR repeat Lge1 PF11488.8 KFY04034.1 - 0.0036 17.4 0.9 0.88 9.8 0.1 2.4 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 SHNi-TPR PF10516.9 KFY04034.1 - 0.0099 15.3 2.6 4.6 6.8 0.0 3.3 3 0 0 3 3 3 1 SHNi-TPR Get5_bdg PF16843.5 KFY04034.1 - 0.01 15.3 0.4 2.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Glu_syn_central PF04898.14 KFY04034.1 - 0.013 15.0 0.3 2.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Glutamate synthase central domain 4HB_MCP_1 PF12729.7 KFY04034.1 - 0.04 13.5 1.1 3.3 7.2 0.1 2.9 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction FACT-Spt16_Nlob PF14826.6 KFY04034.1 - 0.046 13.5 0.0 0.33 10.8 0.0 1.9 1 1 1 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain DHDPS PF00701.22 KFY04034.1 - 0.051 12.3 0.8 1.8 7.2 0.1 2.6 1 1 2 3 3 3 0 Dihydrodipicolinate synthetase family 14-3-3 PF00244.20 KFY04034.1 - 0.051 13.1 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 14-3-3 protein DUF1925 PF09094.11 KFY04034.1 - 0.063 13.6 0.1 15 6.0 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1925) PI3K_P85_iSH2 PF16454.5 KFY04034.1 - 0.076 12.6 2.0 3.1 7.4 0.2 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Type_III_YscG PF09477.10 KFY04034.1 - 0.18 11.9 0.6 53 3.9 0.0 3.0 2 1 0 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Peptidase_C65 PF10275.9 KFY04040.1 - 1e-58 198.7 0.0 1.4e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DUF2796 PF10986.8 KFY04041.1 - 0.024 14.6 2.1 0.036 14.0 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) XRCC4 PF06632.12 KFY04041.1 - 0.081 11.8 3.0 0.12 11.3 3.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 NAD_binding_6 PF08030.12 KFY04042.1 - 1.4e-15 57.8 0.0 3.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFY04042.1 - 1.4e-12 47.8 2.7 1.4e-12 47.8 2.7 2.8 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY04042.1 - 1.4e-09 38.0 0.0 0.0027 17.8 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KFY04042.1 - 6.5e-05 23.5 0.2 0.0019 18.8 0.2 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FTR1 PF03239.14 KFY04043.1 - 3.7e-88 295.6 8.8 4.3e-88 295.4 8.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family B12D PF06522.11 KFY04043.1 - 1.1 9.1 4.0 2.1 8.2 0.6 2.8 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cu-oxidase_2 PF07731.14 KFY04044.1 - 6.3e-44 149.0 7.5 9.5e-41 138.7 0.5 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFY04044.1 - 1.4e-39 134.7 3.9 6.3e-37 126.2 2.7 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFY04044.1 - 7.1e-35 120.5 0.7 3.4e-33 115.0 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase Ank_2 PF12796.7 KFY04044.1 - 4.3e-21 75.3 0.0 6.2e-17 62.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04044.1 - 1.2e-17 64.1 0.0 5.7e-09 36.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY04044.1 - 1.7e-13 50.3 0.0 0.0011 19.4 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 KFY04044.1 - 1.9e-12 46.2 0.0 0.00025 21.2 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KFY04044.1 - 2.7e-07 30.7 0.0 0.01 16.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Zn_clus PF00172.18 KFY04044.1 - 1e-06 28.7 9.5 2.2e-06 27.7 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY04044.1 - 1.3e-06 27.7 0.3 2.9e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupredoxin_1 PF13473.6 KFY04044.1 - 0.028 14.5 0.0 21 5.3 0.0 3.5 3 0 0 3 3 3 0 Cupredoxin-like domain Fungal_trans PF04082.18 KFY04053.1 - 5.6e-26 91.1 0.3 7.5e-26 90.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain C1_2 PF03107.16 KFY04053.1 - 0.15 12.4 1.7 14 6.0 0.0 2.5 2 0 0 2 2 2 0 C1 domain TF_Zn_Ribbon PF08271.12 KFY04053.1 - 0.72 9.4 3.1 1.3 8.6 0.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding adh_short PF00106.25 KFY04054.1 - 8.7e-37 126.5 1.1 1.2e-36 126.0 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04054.1 - 6.9e-34 117.4 0.5 1.2e-33 116.6 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY04054.1 - 3.7e-10 40.0 0.5 6.3e-10 39.2 0.5 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KFY04054.1 - 5e-05 23.3 0.1 9.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 KFY04054.1 - 0.00098 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 KFY04054.1 - 0.0014 19.1 0.1 0.0033 17.8 0.1 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 KFY04054.1 - 0.0069 15.5 0.1 0.0094 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFY04054.1 - 0.015 14.3 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sigma54_activ_2 PF14532.6 KFY04054.1 - 0.033 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain HTHP PF11534.8 KFY04054.1 - 0.17 12.3 0.2 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) DUF5421 PF17458.2 KFY04055.1 - 2.2 7.6 11.1 3.8 6.8 11.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF1996 PF09362.10 KFY04057.1 - 4.1e-72 243.0 2.5 5.8e-72 242.5 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 KFY04057.1 - 5e-06 26.4 6.3 5e-06 26.4 6.3 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Lys PF00062.20 KFY04057.1 - 0.046 14.0 0.1 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family Hemerythrin PF01814.23 KFY04058.1 - 1.9e-07 31.7 0.2 3.7e-07 30.8 0.1 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Peptidase_C65 PF10275.9 KFY04059.1 - 5e-60 203.0 0.0 7.2e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain SAM_1 PF00536.30 KFY04060.1 - 0.018 15.5 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HATPase_c PF02518.26 KFY04061.1 - 3.8e-25 88.6 0.1 1.1e-24 87.1 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFY04061.1 - 6.9e-25 87.4 0.7 2.9e-24 85.4 0.7 2.2 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 KFY04061.1 - 6.9e-19 67.9 0.0 1.4e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KFY04061.1 - 1.3e-16 60.7 0.0 1e-11 45.0 0.0 3.1 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 KFY04061.1 - 7.2e-14 51.6 0.8 1.6e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KFY04061.1 - 2.9e-12 46.8 0.0 3.2e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KFY04061.1 - 0.029 14.4 0.0 0.95 9.6 0.0 2.6 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.12 KFY04061.1 - 0.05 13.9 1.8 4.4 7.7 0.1 3.7 1 1 3 4 4 4 0 PAS fold HATPase_c_3 PF13589.6 KFY04061.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_11 PF08241.12 KFY04061.1 - 0.1 13.3 0.1 72 4.1 0.0 3.5 1 1 2 3 3 3 0 Methyltransferase domain PTSIIB_sorb PF03830.15 KFY04061.1 - 0.48 10.6 2.7 1.4 9.1 0.1 3.0 3 1 1 4 4 4 0 PTS system sorbose subfamily IIB component # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3557-DG3/GCA_000750665.1_DG3_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3557-DG3/GCA_000750665.1_DG3_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3557-DG3/GCA_000750665.1_DG3_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3557-DG3/GCA_000750665.1_DG3_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 04:08:08 2019 # [ok]