# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Retrotran_gag_2 PF14223.6 KII82604.1 - 0.00019 21.1 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII82604.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KII82604.1 - 0.055 13.2 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Chromo PF00385.24 KII82607.1 - 6.7e-11 41.9 0.0 7.2e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF629 PF04780.12 KII82612.1 - 0.0099 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF629) Rpr2 PF04032.16 KII82612.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3788 PF12663.7 KII82612.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) DDE_1 PF03184.19 KII82614.1 - 3.1e-19 69.3 0.0 6.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KII82614.1 - 1.3e-05 25.2 1.0 1.3e-05 25.2 1.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KII82614.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease RAP1 PF07218.11 KII82614.1 - 1.4 7.1 4.1 1.9 6.7 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CENP-B_dimeris PF09026.10 KII82615.1 - 6 7.3 15.0 17 5.9 15.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KII82615.1 - 7.9 4.5 10.2 12 3.8 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Retrotran_gag_2 PF14223.6 KII82618.1 - 2e-08 34.0 0.0 2.3e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HSP70 PF00012.20 KII82621.1 - 3.8e-29 101.4 0.0 4.5e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein adh_short PF00106.25 KII82622.1 - 3.2e-22 79.0 0.1 3.7e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII82622.1 - 2.4e-18 66.5 0.2 2.8e-18 66.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII82622.1 - 0.00023 21.1 0.0 0.00025 21.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII82622.1 - 0.09 12.7 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KII82623.1 - 1.7e-08 34.2 0.0 2.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII82623.1 - 4.8e-06 26.3 0.0 5.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amidase PF01425.21 KII82627.1 - 2.2e-61 208.2 0.1 3e-61 207.8 0.1 1.2 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 KII82629.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Spc7 PF08317.11 KII82631.1 - 0.015 14.2 9.2 0.023 13.6 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KII82631.1 - 2.6 8.7 7.2 1 9.9 3.9 1.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SAP PF02037.27 KII82632.1 - 3.3e-06 26.7 0.0 9.8e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 SAP domain CxC2 PF18803.1 KII82634.1 - 2.8e-43 146.5 0.1 3.9e-43 146.0 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII82634.1 - 0.0036 17.4 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KII82634.1 - 0.0042 17.2 4.5 0.0042 17.2 4.5 1.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) CxC3 PF18804.1 KII82634.1 - 0.0045 16.8 0.0 0.0045 16.8 0.0 2.0 1 1 1 2 2 2 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KII82634.1 - 0.021 15.0 8.6 0.048 13.8 8.6 1.6 1 0 0 1 1 1 0 B-box zinc finger DUF2457 PF10446.9 KII82636.1 - 5.1 6.1 8.9 5.2 6.1 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Herpes_UL56 PF04534.12 KII82638.1 - 0.23 10.9 0.6 0.3 10.6 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein Helicase_C PF00271.31 KII82643.1 - 9e-16 58.2 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII82643.1 - 6.5e-12 45.6 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII82643.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KII82643.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF1264 PF06884.11 KII82643.1 - 0.16 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) DUF1353 PF07087.11 KII82644.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Herpes_ORF11 PF04797.13 KII82645.1 - 0.031 13.1 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus dUTPase protein gag-asp_proteas PF13975.6 KII82645.1 - 0.16 12.6 0.0 0.44 11.1 0.0 1.7 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease adh_short PF00106.25 KII82646.1 - 4.7e-23 81.7 0.1 5.6e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII82646.1 - 4.4e-19 69.0 0.2 5.1e-19 68.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII82646.1 - 0.00019 21.4 0.0 0.0002 21.3 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII82646.1 - 0.023 14.6 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KII82647.1 - 3e-14 52.9 0.2 4.2e-14 52.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII82647.1 - 2.2e-12 47.1 0.0 2.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KDZ PF18758.1 KII82649.1 - 2.5e-61 207.1 0.0 3.6e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82649.1 - 8.7e-07 29.1 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82649.1 - 4.8e-05 23.5 0.0 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases SR-25 PF10500.9 KII82650.1 - 0.0058 16.3 17.3 0.0058 16.3 17.3 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KII82650.1 - 0.079 11.3 22.3 0.066 11.5 19.8 1.8 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 KII82650.1 - 0.42 10.7 26.4 0.022 14.9 20.8 1.6 2 0 0 2 2 2 0 YL1 nuclear protein RR_TM4-6 PF06459.12 KII82650.1 - 2.7 7.7 12.0 4.9 6.9 12.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 KII82650.1 - 5.2 7.5 9.6 10 6.5 9.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Dsh_C PF12316.8 KII82650.1 - 5.7 7.3 9.9 0.2 12.1 4.0 1.6 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Sec62 PF03839.16 KII82650.1 - 5.9 6.3 9.2 14 5.1 9.2 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Atrophin-1 PF03154.15 KII82650.1 - 6.7 4.9 11.5 9.5 4.4 11.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peroxidase_2 PF01328.17 KII82653.1 - 0.039 14.5 0.0 0.046 14.3 0.0 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 PhnA_Zn_Ribbon PF08274.12 KII82654.1 - 0.067 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon gag-asp_proteas PF13975.6 KII82658.1 - 0.047 14.2 0.0 0.15 12.7 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.13 KII82658.1 - 0.065 12.0 0.0 0.11 11.2 0.0 1.3 2 0 0 2 2 2 0 Herpesvirus dUTPase protein RNA_pol PF00940.19 KII82659.1 - 8.1e-16 57.9 0.0 8.5e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Ectatomin PF06457.11 KII82663.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Ectatomin Retrotran_gag_2 PF14223.6 KII82665.1 - 6.2e-09 35.6 0.1 8.9e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type OCC1 PF15506.6 KII82668.1 - 0.91 9.7 4.0 4 7.6 0.0 2.8 3 0 0 3 3 3 0 OCC1 family NOA36 PF06524.12 KII82670.1 - 1.4 8.2 4.6 1.9 7.7 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF3704 PF12488.8 KII82671.1 - 0.053 13.2 4.6 0.57 9.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3704) TniB PF05621.11 KII82674.1 - 0.23 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein PT PF04886.12 KII82677.1 - 0.15 11.6 10.7 0.87 9.2 2.7 2.8 1 1 2 3 3 3 0 PT repeat zf-C2HC5 PF06221.13 KII82678.1 - 4.1 7.5 8.5 0.2 11.7 0.8 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type ESR1_C PF12743.7 KII82680.1 - 0.29 10.9 2.8 0.65 9.8 2.8 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal zf-CCHC_5 PF14787.6 KII82684.1 - 0.83 9.4 3.0 3.6 7.4 3.0 2.1 1 1 0 1 1 1 0 GAG-polyprotein viral zinc-finger MtrH PF02007.18 KII82685.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit zf-CCHC PF00098.23 KII82692.1 - 0.27 11.4 2.2 0.51 10.5 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1943 PF09172.11 KII82695.1 - 0.008 15.4 0.3 1.4 8.1 0.0 2.5 1 1 0 2 2 2 2 Domain of unknown function (DUF1943) MspA PF09203.11 KII82695.1 - 8.9 6.1 19.2 39 4.1 0.4 3.5 1 1 1 2 2 2 0 MspA DEAD PF00270.29 KII82699.1 - 0.00065 19.5 0.0 0.0008 19.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII82699.1 - 0.063 13.3 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KRAB PF01352.27 KII82700.1 - 0.18 11.5 0.0 20 4.9 0.0 2.3 2 0 0 2 2 2 0 KRAB box CSTF_C PF14304.6 KII82701.1 - 0.0014 18.2 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal FlgM PF04316.13 KII82701.1 - 0.02 15.3 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF3526 PF12040.8 KII82701.1 - 0.093 13.2 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) DUF1248 PF06852.12 KII82703.1 - 0.13 11.7 0.6 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) cwf21 PF08312.12 KII82703.1 - 0.18 12.0 0.4 7.7 6.8 0.1 2.5 2 0 0 2 2 2 0 cwf21 domain Extensin_2 PF04554.13 KII82706.1 - 0.5 10.5 31.6 1.8e+04 -8.1 32.5 3.0 1 1 0 1 1 1 0 Extensin-like region zf-CCHC PF00098.23 KII82707.1 - 0.29 11.3 2.3 0.66 10.1 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle NDC10_II PF16787.5 KII82712.1 - 1.9e-09 37.1 0.0 2.5e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Glyco_transf_20 PF00982.21 KII82713.1 - 4.1e-11 42.2 0.0 5.2e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Retrotran_gag_2 PF14223.6 KII82715.1 - 4.4e-08 32.9 0.1 6.4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII82715.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KII82715.1 - 0.11 12.2 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Hydin_ADK PF17213.3 KII82717.1 - 2.5 8.4 10.3 0.053 13.8 1.5 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain BHD_1 PF10403.9 KII82718.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.7 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 1 Spermine_synth PF01564.17 KII82719.1 - 1.1e-68 230.4 0.0 2.1e-68 229.5 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KII82719.1 - 6.4e-24 83.6 0.1 1.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KII82719.1 - 1.5e-05 25.6 0.0 2.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII82719.1 - 0.0011 19.6 0.0 0.0034 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KII82719.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KII82719.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 KII82719.1 - 0.046 13.3 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KII82719.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 KII82719.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain ABC_tran PF00005.27 KII82723.1 - 0.0033 18.0 0.0 0.0038 17.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII82723.1 - 0.059 13.2 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KII82723.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Pilus_CpaD PF09476.10 KII82723.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) KDZ PF18758.1 KII82726.1 - 1.4e-33 116.4 0.0 1.6e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KII82727.1 - 4.5e-12 46.1 0.1 5.2e-12 45.9 0.1 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82728.1 - 3.4e-10 40.0 0.1 5.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82728.1 - 7.3e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII82729.1 - 1e-37 129.9 0.0 1.5e-35 122.9 0.0 2.3 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Abhydrolase_1 PF00561.20 KII82730.1 - 1.5e-23 83.8 0.0 3.2e-21 76.1 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KII82730.1 - 7.1e-19 67.8 0.1 2e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KII82730.1 - 0.029 13.6 0.0 6 6.1 0.0 3.1 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PT PF04886.12 KII82734.1 - 0.83 9.3 5.1 5.1 6.7 5.1 2.2 1 1 0 1 1 1 0 PT repeat NUP50 PF08911.11 KII82734.1 - 7.2 7.4 7.2 0.39 11.4 0.9 2.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) GST_C_2 PF13410.6 KII82737.1 - 1.2e-05 25.2 0.5 4.1e-05 23.5 0.5 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII82737.1 - 0.0015 18.7 0.2 0.0065 16.7 0.2 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.10 KII82737.1 - 0.015 15.6 0.6 0.13 12.5 0.2 2.2 2 0 0 2 2 2 0 YopE, N terminal GST_C_3 PF14497.6 KII82737.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Retrotran_gag_2 PF14223.6 KII82738.1 - 1.5e-18 66.8 0.1 1.6e-18 66.7 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RCC1 PF00415.18 KII82740.1 - 3.6e-55 184.4 17.2 2.9e-09 37.4 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII82740.1 - 2.3e-41 138.8 47.2 1.7e-07 30.8 0.3 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 KII82740.1 - 0.021 14.6 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Hox9_act PF04617.13 KII82741.1 - 0.25 12.1 4.6 0.43 11.3 4.6 1.5 1 0 0 1 1 1 0 Hox9 activation region Interferon PF00143.19 KII82744.1 - 0.23 11.6 0.0 0.28 11.3 0.0 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain Retrotran_gag_3 PF14244.6 KII82746.1 - 0.0066 16.2 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KII82746.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Amidase02_C PF12123.8 KII82747.1 - 0.07 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Nop52 PF05997.12 KII82747.1 - 0.18 11.5 0.1 0.22 11.3 0.1 1.1 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Peptidase_C48 PF02902.19 KII82748.1 - 0.0031 17.4 0.1 0.0054 16.6 0.1 1.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF5586 PF17824.1 KII82749.1 - 0.094 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF1175 PF06672.11 KII82751.1 - 0.075 12.7 0.1 0.13 11.9 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Acid_PPase PF12689.7 KII82751.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase DUF4611 PF15387.6 KII82754.1 - 0.0019 18.4 9.0 0.0019 18.4 9.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KII82754.1 - 0.0067 16.8 4.3 0.0067 16.8 4.3 2.0 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 KII82754.1 - 0.023 14.4 3.0 0.023 14.4 3.0 1.6 2 0 0 2 2 2 0 FAM176 family DUF5423 PF17461.2 KII82754.1 - 0.11 11.4 0.7 0.15 10.9 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Myc_N PF01056.18 KII82754.1 - 0.51 10.2 10.0 0.69 9.7 10.0 1.3 1 1 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 KII82754.1 - 0.88 8.8 10.3 1.3 8.3 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein CPSF100_C PF13299.6 KII82754.1 - 2.8 8.1 7.8 1.3 9.2 0.7 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 KII82754.1 - 3.2 6.9 4.8 5.1 6.2 4.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 KII82754.1 - 3.3 5.7 10.6 4.5 5.3 10.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi MRNIP PF15749.5 KII82754.1 - 7.2 7.4 9.0 0.7 10.6 3.1 1.9 2 0 0 2 2 2 0 MRN-interacting protein WW_1 PF18507.1 KII82758.1 - 0.068 12.9 0.6 0.17 11.6 0.6 1.6 1 0 0 1 1 1 0 WW domain Pkinase_Tyr PF07714.17 KII82764.1 - 0.00019 20.8 0.0 0.0002 20.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII82764.1 - 0.012 15.0 0.0 0.013 14.9 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain HTH_32 PF13565.6 KII82766.1 - 0.0029 18.2 0.1 0.0064 17.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KII82766.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KII82766.1 - 0.008 15.8 0.1 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 KII82766.1 - 0.033 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase HTH_29 PF13551.6 KII82766.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KII82766.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DEC-1_N PF04625.13 KII82767.1 - 3.1 6.7 8.2 3.9 6.4 8.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Chromo PF00385.24 KII82770.1 - 1.9e-10 40.5 0.0 2.1e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DLIC PF05783.11 KII82771.1 - 0.18 10.6 0.8 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) COX1 PF00115.20 KII82777.1 - 3.4e-07 29.5 0.5 3.6e-07 29.4 0.5 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 KII82778.1 - 1.4e-21 76.9 5.3 1.5e-21 76.8 5.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Transp_cyt_pur PF02133.15 KII82781.1 - 4.3e-10 39.0 0.5 6.4e-07 28.5 0.2 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2970 PF11174.8 KII82781.1 - 0.018 14.8 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) FAM167 PF11652.8 KII82782.1 - 0.059 13.9 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 FAM167 Dimer_Tnp_hAT PF05699.14 KII82784.1 - 6e-09 35.6 0.1 7.7e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3692 PF12469.8 KII82788.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 CRISPR-associated protein RVP PF00077.20 KII82795.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.10 KII82795.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 KII82795.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease NADH_dh_m_C1 PF15088.6 KII82802.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial KDZ PF18758.1 KII82805.1 - 6e-63 212.4 0.0 9.8e-63 211.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82805.1 - 2e-07 31.1 0.1 5.2e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82805.1 - 9.8e-05 22.5 0.1 0.00026 21.1 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1690 PF07956.11 KII82805.1 - 3.4 8.1 9.3 3 8.3 2.9 2.5 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Adenylsucc_synt PF00709.21 KII82807.1 - 0.076 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase REF PF05755.12 KII82807.1 - 0.093 12.5 0.0 0.32 10.8 0.0 1.7 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) GrpE PF01025.19 KII82810.1 - 0.13 11.9 0.1 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 GrpE Alpha_GJ PF03229.13 KII82811.1 - 0.024 15.2 4.0 0.047 14.2 0.2 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J Proton_antipo_M PF00361.20 KII82812.1 - 4.8e-35 121.2 9.0 5.1e-35 121.1 9.0 1.0 1 0 0 1 1 1 1 Proton-conducting membrane transporter His_Phos_1 PF00300.22 KII82814.1 - 0.0076 16.0 2.4 0.042 13.5 0.4 2.1 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Astro_capsid_p PF12226.8 KII82814.1 - 0.2 10.8 4.8 0.31 10.2 4.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KII82814.1 - 9.4 5.5 7.9 6.9 5.9 6.0 1.6 2 0 0 2 2 2 0 NOA36 protein Biotin_carb_N PF00289.22 KII82816.1 - 3.6e-14 53.2 0.0 9.8e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KII82817.1 - 3.7e-17 62.4 0.0 2.8e-16 59.5 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ACC_central PF08326.12 KII82817.1 - 2.7e-09 35.8 0.0 3.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region zf-RVT PF13966.6 KII82821.1 - 0.0045 17.7 0.9 0.0045 17.7 0.9 2.3 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KII82822.1 - 7.8e-05 22.3 0.0 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.6 KII82824.1 - 2.9e-18 66.0 0.0 4.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KII82824.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain ATP-synt_C PF00137.21 KII82825.1 - 1.7e-13 50.7 13.9 2.4e-13 50.2 13.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit C DDE_1 PF03184.19 KII82826.1 - 4.5e-05 23.2 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FlgI PF02119.16 KII82827.1 - 0.15 10.9 1.6 0.49 9.3 0.4 1.9 1 1 1 2 2 2 0 Flagellar P-ring protein Helicase_C PF00271.31 KII82828.1 - 3.6e-12 46.6 0.0 2.8e-11 43.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII82828.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bep_C_terminal PF17841.1 KII82828.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) CDV3 PF15359.6 KII82830.1 - 0.057 13.9 0.9 0.16 12.4 0.9 1.7 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 rve_3 PF13683.6 KII82830.1 - 0.1 12.4 0.2 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Integrase core domain Chromo PF00385.24 KII82831.1 - 3.8e-14 52.3 0.0 4.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3710 PF12502.8 KII82833.1 - 0.18 11.4 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) Ish1 PF10281.9 KII82834.1 - 0.00036 20.8 5.9 0.0084 16.4 1.3 2.7 3 0 0 3 3 3 2 Putative stress-responsive nuclear envelope protein Extensin_2 PF04554.13 KII82836.1 - 0.5 10.5 31.6 1.8e+04 -8.1 32.5 3.0 1 1 0 1 1 1 0 Extensin-like region Helicase_C PF00271.31 KII82837.1 - 9.3e-12 45.3 0.0 5.9e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII82837.1 - 3.2e-06 27.0 0.0 6.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KII82837.1 - 0.0089 16.7 0.6 0.023 15.4 0.6 1.6 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KII82837.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KII82837.1 - 0.064 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T4SS-DNA_transf PF02534.14 KII82837.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Grg1 PF11034.8 KII82837.1 - 0.12 12.7 2.9 0.21 11.8 2.9 1.4 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 MMR_HSR1 PF01926.23 KII82840.1 - 4e-06 26.9 0.0 8.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KII82840.1 - 0.00033 20.5 1.1 0.052 13.3 0.0 2.4 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Arf PF00025.21 KII82840.1 - 0.0015 18.1 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 KII82840.1 - 0.0036 16.5 0.0 0.43 9.7 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit TniB PF05621.11 KII82840.1 - 0.0042 16.5 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein ABC_tran PF00005.27 KII82840.1 - 0.0044 17.5 0.0 0.009 16.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KII82840.1 - 0.0074 16.6 0.1 0.092 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KII82840.1 - 0.0083 16.6 0.1 0.18 12.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SART-1 PF03343.13 KII82840.1 - 0.0094 14.6 2.3 0.012 14.2 2.3 1.1 1 0 0 1 1 1 1 SART-1 family PduV-EutP PF10662.9 KII82840.1 - 0.012 15.4 0.0 0.046 13.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 KII82840.1 - 0.016 14.7 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 KII82840.1 - 0.018 15.4 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 RNA helicase Roc PF08477.13 KII82840.1 - 0.021 15.1 0.0 0.12 12.6 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2326 PF10088.9 KII82840.1 - 0.029 14.1 0.1 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) ATPase_2 PF01637.18 KII82840.1 - 0.052 13.4 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KII82840.1 - 0.061 13.0 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KII82840.1 - 0.061 13.8 0.5 2.4 8.6 0.5 2.3 1 1 0 1 1 1 0 AAA domain DUF3093 PF11292.8 KII82840.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) FeoB_N PF02421.18 KII82840.1 - 0.23 11.0 1.2 0.49 9.9 0.0 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Herpes_BLLF1 PF05109.13 KII82842.1 - 0.036 12.1 4.6 0.047 11.7 4.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) MoeA_N PF03453.17 KII82842.1 - 0.47 10.2 5.8 1.4 8.6 5.8 1.8 1 1 0 1 1 1 0 MoeA N-terminal region (domain I and II) Retrotran_gag_2 PF14223.6 KII82844.1 - 2.8e-16 59.4 0.0 4.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII82844.1 - 0.0077 16.3 4.8 0.013 15.5 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KII82844.1 - 0.28 11.0 3.9 0.49 10.3 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Hemocyanin_C PF03723.14 KII82851.1 - 0.14 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Hemocyanin, ig-like domain CxC4 PF18717.1 KII82852.1 - 3.5e-43 146.6 0.9 3.5e-43 146.6 0.9 2.5 3 0 0 3 3 3 1 CxC4 like cysteine cluster associated with KDZ transposases Exo5 PF09810.9 KII82852.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DUF498 PF04430.14 KII82853.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Flot PF15975.5 KII82853.1 - 0.29 11.3 12.6 0.28 11.4 0.6 2.8 2 1 0 2 2 2 0 Flotillin DUF4140 PF13600.6 KII82853.1 - 0.47 10.9 3.8 0.99 9.9 3.8 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DDE_3 PF13358.6 KII82854.1 - 9.7e-08 31.9 0.1 0.022 14.5 0.0 3.3 3 0 0 3 3 3 3 DDE superfamily endonuclease RVT_1 PF00078.27 KII82858.1 - 5.1e-07 29.4 0.1 5.9e-07 29.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.29 KII82860.1 - 2.2e-11 43.9 0.0 3.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII82860.1 - 0.00097 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII82860.1 - 0.0068 16.7 0.0 0.023 15.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII82860.1 - 0.25 12.1 1.3 0.56 11.0 1.3 1.6 1 0 0 1 1 1 0 RecQ zinc-binding OrsD PF12013.8 KII82861.1 - 6.5e-13 49.1 6.4 2.4e-12 47.3 1.8 2.5 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3903 PF13043.6 KII82864.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) DNA_primase_S PF01896.19 KII82865.1 - 7.4e-32 110.8 0.0 1.1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit zf-RING_UBOX PF13445.6 KII82866.1 - 2.2e-07 30.7 7.3 4.6e-07 29.8 7.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII82866.1 - 8.2e-07 28.8 5.3 8.2e-07 28.8 5.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII82866.1 - 1.9e-06 27.7 7.3 4e-06 26.6 7.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII82866.1 - 2.6e-06 27.5 4.7 5.3e-06 26.5 4.7 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII82866.1 - 2.9e-06 27.5 9.8 4.4e-06 26.9 9.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII82866.1 - 0.00012 21.8 6.8 0.00037 20.3 6.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII82866.1 - 0.0004 20.2 5.9 0.00089 19.1 5.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KII82866.1 - 0.00081 19.3 8.6 0.0016 18.4 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 KII82866.1 - 0.17 12.1 6.6 0.5 10.6 6.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain LRR_6 PF13516.6 KII82867.1 - 0.004 17.1 0.4 5.1 7.4 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich repeat zf-CCHC PF00098.23 KII82870.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle His_Phos_1 PF00300.22 KII82871.1 - 0.067 12.9 1.4 0.34 10.6 0.3 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) NOA36 PF06524.12 KII82871.1 - 1.3 8.3 5.5 2.8 7.2 5.5 1.5 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 KII82871.1 - 5.5 6.0 8.8 9.9 5.2 8.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HMG_box PF00505.19 KII82872.1 - 0.12 12.8 9.4 0.2 12.1 5.1 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box NADH_dh_m_C1 PF15088.6 KII82874.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial FOXP-CC PF16159.5 KII82877.1 - 0.25 12.0 9.0 1.7 9.4 0.5 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KII82877.1 - 0.53 11.3 12.0 2 9.5 0.7 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KII82877.1 - 0.78 10.1 4.8 0.26 11.6 1.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon Plavaka PF18759.1 KII82881.1 - 4.3e-23 82.0 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KII82882.1 - 1e-69 235.3 0.2 1.1e-69 235.1 0.2 1.0 1 0 0 1 1 1 1 Plavaka transposase DUF4197 PF13852.6 KII82882.1 - 0.094 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) CCDC24 PF15669.5 KII82883.1 - 7.5 6.4 8.1 18 5.1 7.6 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family GRP PF07172.11 KII82885.1 - 0.063 14.0 0.6 0.063 14.0 0.6 2.4 2 1 0 2 2 2 0 Glycine rich protein family Replicase PF03090.17 KII82887.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Replicase family FYVE_2 PF02318.16 KII82889.1 - 0.03 14.5 3.3 0.064 13.5 3.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3900 PF13039.6 KII82889.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) DUF4257 PF14074.6 KII82891.1 - 0.056 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) Tet_JBP PF12851.7 KII82893.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Retrotran_gag_2 PF14223.6 KII82896.1 - 8.8e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type GIT1_C PF12205.8 KII82896.1 - 0.099 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term zf-MYND PF01753.18 KII82899.1 - 3.8e-08 33.3 10.6 6.1e-08 32.6 10.6 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KII82899.1 - 0.34 10.8 7.9 0.62 10.0 7.9 1.5 1 0 0 1 1 1 0 HIT zinc finger Zn_clus PF00172.18 KII82901.1 - 0.066 13.3 12.8 0.22 11.7 1.8 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.28 KII82902.1 - 6.7e-10 39.6 0.1 3.1e-07 31.0 0.0 2.5 2 1 0 2 2 2 2 SET domain DUF3060 PF11259.8 KII82902.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) Macoilin PF09726.9 KII82903.1 - 0.0064 15.1 4.9 0.0082 14.8 4.9 1.1 1 0 0 1 1 1 1 Macoilin family DivIC PF04977.15 KII82903.1 - 0.0083 15.9 3.2 0.031 14.0 3.2 1.9 1 1 0 1 1 1 1 Septum formation initiator ZapB PF06005.12 KII82903.1 - 0.011 16.2 1.0 0.027 14.9 1.0 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Fez1 PF06818.15 KII82903.1 - 0.015 15.8 0.3 0.015 15.8 0.3 1.5 2 0 0 2 2 1 0 Fez1 Taxilin PF09728.9 KII82903.1 - 0.02 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein GIT_CC PF16559.5 KII82903.1 - 0.025 14.5 2.6 0.027 14.3 1.0 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 KII82903.1 - 0.03 13.2 0.9 0.045 12.6 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2205 PF10224.9 KII82903.1 - 0.03 14.3 0.5 0.072 13.1 0.5 1.7 1 0 0 1 1 1 0 Short coiled-coil protein Filament PF00038.21 KII82903.1 - 0.035 13.7 2.3 0.068 12.7 2.0 1.5 1 1 1 2 2 2 0 Intermediate filament protein SHE3 PF17078.5 KII82903.1 - 0.038 13.7 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4140 PF13600.6 KII82903.1 - 0.042 14.3 1.2 0.62 10.5 0.3 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 KII82903.1 - 0.055 14.0 0.3 0.092 13.3 0.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5082 PF16888.5 KII82903.1 - 0.055 13.8 0.3 0.1 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 KII82903.1 - 0.075 13.4 0.3 0.2 12.0 0.3 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KII82903.1 - 0.079 13.1 0.9 1.1 9.4 0.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 KII82903.1 - 0.086 13.3 0.2 0.4 11.1 0.3 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 KII82903.1 - 0.1 12.9 1.1 1.8 8.9 0.5 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 KII82903.1 - 0.11 11.8 1.9 0.19 11.1 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 KII82903.1 - 0.14 11.5 0.4 0.23 10.8 0.4 1.3 1 1 0 1 1 1 0 FAM76 protein Ribosomal_L29 PF00831.23 KII82903.1 - 0.19 11.7 1.1 0.5 10.4 0.8 1.9 1 1 0 1 1 1 0 Ribosomal L29 protein ATG16 PF08614.11 KII82903.1 - 2.7 8.1 14.7 17 5.6 14.4 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PV-1 PF06637.11 KII82904.1 - 0.28 9.9 19.7 0.12 11.2 16.0 2.0 1 1 1 2 2 2 0 PV-1 protein (PLVAP) HCMV_UL139 PF12507.8 KII82904.1 - 0.39 11.1 7.8 0.55 10.6 0.7 2.6 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Med9 PF07544.13 KII82904.1 - 1.7 8.8 10.2 3 8.0 0.2 3.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Golgin_A5 PF09787.9 KII82904.1 - 4.3 6.7 29.2 0.47 9.9 21.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Nre_C PF04895.12 KII82904.1 - 6.1 6.8 6.5 41 4.1 0.0 3.3 2 1 1 3 3 3 0 Archaeal Nre, C-terminal SCP1201-deam PF14428.6 KII82905.1 - 0.11 12.3 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 SCP1.201-like deaminase Glutaredoxin PF00462.24 KII82907.1 - 0.21 11.8 1.5 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Glutaredoxin PIF1 PF05970.14 KII82908.1 - 0.0016 17.7 2.6 0.23 10.6 0.7 2.9 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KII82908.1 - 0.043 13.5 0.1 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rap1a PF18602.1 KII82913.1 - 0.22 11.8 1.3 8.1 6.8 0.1 2.8 2 0 0 2 2 2 0 Rap1a immunity proteins OGFr_III PF04680.13 KII82914.1 - 0.064 13.9 3.0 0.064 13.9 3.0 2.2 2 0 0 2 2 2 0 Opioid growth factor receptor repeat Peptidase_C48 PF02902.19 KII82916.1 - 1.1e-05 25.4 1.5 0.00018 21.4 1.5 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF659 PF04937.15 KII82917.1 - 2.1e-13 50.4 0.0 3.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Cauli_VI PF01693.16 KII82919.1 - 6.5e-08 32.7 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin KDZ PF18758.1 KII82921.1 - 5.3e-51 173.4 0.0 8.2e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII82921.1 - 3.5e-38 130.1 0.0 7.6e-38 129.0 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII82921.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Retrotran_gag_2 PF14223.6 KII82930.1 - 6.9e-08 32.2 0.1 9.8e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Astro_capsid_p PF12226.8 KII82933.1 - 0.063 12.4 2.3 0.095 11.8 2.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein KDZ PF18758.1 KII82934.1 - 1.1e-63 214.8 0.0 2e-63 214.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82934.1 - 1.1e-08 35.2 0.1 2.4e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82934.1 - 2.4e-07 30.9 0.1 7.3e-07 29.3 0.1 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Phe_tRNA-synt_N PF02912.18 KII82934.1 - 0.072 13.0 1.6 9.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF2959 PF11172.8 KII82934.1 - 2.6 8.1 5.4 17 5.5 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Herpes_ORF11 PF04797.13 KII82938.1 - 0.0039 16.1 0.0 0.0084 15.0 0.0 1.4 2 0 0 2 2 2 1 Herpesvirus dUTPase protein gag-asp_proteas PF13975.6 KII82938.1 - 0.021 15.4 0.0 0.056 14.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Chromo PF00385.24 KII82940.1 - 1.5e-10 40.8 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.23 KII82945.1 - 3e-50 170.9 0.0 5.4e-50 170.1 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII82945.1 - 4e-08 33.6 0.0 1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII82945.1 - 6.2e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KII82945.1 - 3.3e-05 23.7 3.2 8.6e-05 22.4 3.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII82945.1 - 7.1e-05 22.6 5.7 0.00044 20.1 5.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII82945.1 - 0.00035 20.5 1.5 0.00075 19.5 1.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII82945.1 - 0.00035 20.3 2.4 0.00035 20.3 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SWI2_SNF2 PF18766.1 KII82945.1 - 0.0054 16.4 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-RING_2 PF13639.6 KII82945.1 - 0.0081 16.5 5.3 0.0081 16.5 5.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KII82945.1 - 0.016 15.4 4.7 0.016 15.4 4.7 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KII82945.1 - 0.042 13.7 8.1 0.025 14.4 3.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KII82945.1 - 0.11 12.7 2.2 0.23 11.6 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger RLAN PF14401.6 KII82945.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain DZR PF12773.7 KII82945.1 - 0.45 10.6 2.7 53 3.9 0.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 KII82945.1 - 3.6 7.9 5.2 2 8.7 2.0 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Retrotran_gag_2 PF14223.6 KII82946.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Nop14 PF04147.12 KII82947.1 - 0.014 13.7 30.3 0.024 12.9 30.3 1.5 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KII82947.1 - 0.28 9.5 26.7 0.66 8.2 26.7 1.7 1 0 0 1 1 1 0 CDC45-like protein TolA_bind_tri PF16331.5 KII82947.1 - 0.89 9.7 16.0 0.14 12.3 5.3 3.9 3 1 1 4 4 4 0 TolA binding protein trimerisation Zip PF02535.22 KII82947.1 - 2 7.5 4.8 3.4 6.8 4.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 KII82948.1 - 1.5 6.8 13.4 2.3 6.2 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fib_alpha PF08702.10 KII82948.1 - 1.7 8.8 4.0 4.1 7.6 4.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 KII82948.1 - 3.1 8.0 34.8 2.8 8.1 8.4 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 KII82948.1 - 6.1 5.8 11.4 0.47 9.5 6.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KII82948.1 - 8.5 6.8 25.0 0.024 15.1 10.8 2.9 2 1 1 3 3 3 0 Fez1 AAA_11 PF13086.6 KII82950.1 - 1.6 8.4 5.9 2.5 7.8 5.9 1.2 1 0 0 1 1 1 0 AAA domain XRN_M PF17846.1 KII82950.1 - 9.7 5.0 7.3 13 4.6 7.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Ribosomal_L27e PF01777.18 KII82951.1 - 0.012 16.0 1.1 0.018 15.4 1.1 1.2 1 0 0 1 1 1 0 Ribosomal L27e protein family TPR_10 PF13374.6 KII82951.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SNF2_N PF00176.23 KII82952.1 - 2.7e-12 46.1 0.0 4.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII82952.1 - 2.9e-11 43.7 0.0 6.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KII82952.1 - 0.0011 18.3 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_L27e PF01777.18 KII82955.1 - 1.3e-14 54.3 0.0 1.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family DUF659 PF04937.15 KII82956.1 - 0.011 15.6 0.0 0.012 15.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KII82957.1 - 5.5e-09 35.7 0.2 5.8e-09 35.6 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Plavaka PF18759.1 KII82959.1 - 1.7e-112 375.8 0.1 2.3e-112 375.4 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase OrsD PF12013.8 KII82961.1 - 0.019 15.4 5.1 9.1 6.8 5.1 2.8 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Dimer_Tnp_hAT PF05699.14 KII82962.1 - 1.4e-10 40.9 0.1 1.8e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-BglII PF09195.11 KII82963.1 - 0.11 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BglII Retrotran_gag_2 PF14223.6 KII82968.1 - 8.3e-13 48.2 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KII82970.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HepII_C PF18675.1 KII82970.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Heparinase II C-terminal domain Retrotran_gag_3 PF14244.6 KII82970.1 - 0.21 11.4 1.6 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Cytochrom_C PF00034.21 KII82975.1 - 0.34 12.1 2.8 0.99 10.6 0.0 2.9 2 1 0 2 2 2 0 Cytochrome c KDZ PF18758.1 KII82977.1 - 6.6e-64 215.6 0.0 1.1e-63 214.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82977.1 - 1.5e-07 31.5 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82977.1 - 9.4e-05 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1639 PF07797.14 KII82979.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) UBA2_C PF16195.5 KII82980.1 - 0.069 13.9 6.8 0.099 13.3 6.2 1.5 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Ecl1 PF12855.7 KII82980.1 - 0.42 11.8 8.6 0.92 10.6 8.6 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins KDZ PF18758.1 KII82981.1 - 5.6e-63 212.5 0.2 1.3e-62 211.3 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82981.1 - 3.2e-09 36.9 0.1 6.8e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82981.1 - 5.2e-05 23.4 0.2 0.00011 22.4 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RVT_1 PF00078.27 KII82983.1 - 6.1e-08 32.4 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PGC7_Stella PF15549.6 KII82984.1 - 6.3 6.8 7.0 5 7.1 5.3 1.6 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain zf-RVT PF13966.6 KII82985.1 - 3.5e-08 34.0 0.4 3.5e-08 34.0 0.4 2.2 2 1 1 3 3 3 1 zinc-binding in reverse transcriptase AT_hook PF02178.19 KII82986.1 - 0.54 10.3 6.0 2 8.5 6.0 2.0 1 0 0 1 1 1 0 AT hook motif Plavaka PF18759.1 KII82987.1 - 3e-28 99.0 2.1 5.1e-18 65.4 0.0 3.4 3 1 1 4 4 4 2 Plavaka transposase CSN7a_helixI PF18392.1 KII82987.1 - 2 8.4 3.7 15 5.6 0.2 2.7 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain BORG_CEP PF14957.6 KII82988.1 - 1.9 9.7 5.5 2.8 9.1 5.5 1.2 1 0 0 1 1 1 0 Cdc42 effector RR_TM4-6 PF06459.12 KII82988.1 - 2.2 8.1 10.3 2.5 7.8 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KII82988.1 - 2.9 6.6 6.3 3.2 6.4 6.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 KII82988.1 - 5.5 7.1 13.3 7.7 6.7 13.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF2639 PF11121.8 KII82990.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) CDC45 PF02724.14 KII82990.1 - 0.21 9.8 2.8 0.26 9.6 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KII82990.1 - 3.7 5.6 10.9 4.7 5.3 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KII82990.1 - 4.9 6.4 12.7 6.8 5.9 12.7 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KII82990.1 - 6.8 4.6 14.5 8.9 4.3 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 KII82992.1 - 0.083 13.1 0.9 0.32 11.2 0.1 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain Pkinase PF00069.25 KII82993.1 - 6.9e-21 74.8 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII82993.1 - 0.12 11.6 0.0 0.39 9.9 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase KDZ PF18758.1 KII82995.1 - 1.7e-62 211.0 0.0 2.8e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII82995.1 - 4.1e-08 33.3 0.2 9e-08 32.2 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII82995.1 - 5.3e-05 23.3 0.4 0.00013 22.1 0.4 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Bud13 PF09736.9 KII82996.1 - 0.13 12.7 3.2 0.1 13.0 1.4 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.12 KII82997.1 - 5.7 6.7 9.2 6.7 6.5 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MGTL PF17059.5 KII82997.1 - 6.2 6.8 7.4 2.1 8.3 0.3 2.7 2 0 0 2 2 2 0 MgtA leader peptide KDZ PF18758.1 KII83000.1 - 1.8e-64 217.4 0.0 2.8e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83000.1 - 7.8e-09 35.6 0.1 1.8e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII83000.1 - 2.7e-06 27.5 0.2 5.8e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PIF1 PF05970.14 KII83001.1 - 0.00028 20.2 0.1 0.0029 16.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 KII83001.1 - 0.0051 16.6 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent RecD-like DNA helicase SH3 domain SMODS PF18144.1 KII83001.1 - 0.081 13.1 0.1 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain PIF1 PF05970.14 KII83002.1 - 1.6e-05 24.2 0.6 1.7e-05 24.2 0.6 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KII83002.1 - 0.0015 18.9 0.2 0.0019 18.5 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII83002.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KII83002.1 - 0.0063 16.3 0.1 0.0063 16.3 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KII83002.1 - 0.06 13.6 0.1 0.06 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain F-box PF00646.33 KII83005.1 - 0.017 15.0 2.3 0.34 10.9 0.1 3.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KII83005.1 - 0.16 11.9 2.5 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII83007.1 - 0.11 12.3 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 F-box-like ELYS PF13934.6 KII83009.1 - 0.022 14.7 0.1 0.024 14.6 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore complex assembly Tocopherol_cycl PF14249.6 KII83010.1 - 0.038 13.1 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Tocopherol cyclase PHD PF00628.29 KII83013.1 - 3.1 7.8 6.6 7.4 6.5 6.6 1.6 1 1 0 1 1 1 0 PHD-finger BRF1 PF07741.13 KII83015.1 - 0.021 15.2 0.4 0.092 13.1 0.4 2.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain OrsD PF12013.8 KII83016.1 - 2.3e-08 34.5 2.4 9e-08 32.6 2.4 2.1 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D DEAD PF00270.29 KII83016.1 - 2.6e-08 33.8 0.1 1.1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII83016.1 - 4.7e-06 26.9 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII83016.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C2H2_12 PF18658.1 KII83016.1 - 5.5 6.6 6.2 1.8 8.2 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger C2H2-type Plavaka PF18759.1 KII83018.1 - 2.4e-132 441.1 0.1 3.7e-132 440.4 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase Glyco_hydro_15 PF00723.21 KII83020.1 - 7.1e-89 298.6 0.1 8.5e-89 298.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KII83020.1 - 3.6e-28 97.3 0.2 8.5e-28 96.1 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain Torus PF16131.5 KII83021.1 - 1.6e-16 60.9 2.6 5.5e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 KII83021.1 - 1.9e-12 46.8 21.8 7.8e-06 25.8 3.1 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 KII83021.1 - 2.4e-11 43.2 18.6 0.0002 21.2 0.3 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII83021.1 - 1.5e-09 37.4 31.1 2.3e-07 30.4 3.8 3.8 4 0 0 4 4 4 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KII83021.1 - 1.3e-06 28.7 22.3 0.0094 16.4 1.8 3.4 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KII83021.1 - 7e-05 23.0 10.1 0.018 15.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger containing family CLIP PF12032.8 KII83021.1 - 0.098 13.0 0.0 7.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Regulatory CLIP domain of proteinases MATH PF00917.26 KII83022.1 - 5.4e-06 26.5 0.1 9.7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KII83022.1 - 0.00015 22.0 0.0 2 8.7 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain FAD_binding_2 PF00890.24 KII83023.1 - 1.7e-42 146.0 4.4 2.7e-37 128.8 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KII83023.1 - 1.9e-06 27.5 1.2 2.4e-05 23.9 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII83023.1 - 4.7e-06 26.0 0.1 0.0075 15.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII83023.1 - 0.00083 18.5 0.4 0.00083 18.5 0.4 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KII83023.1 - 0.0023 16.7 1.1 0.3 9.7 0.1 2.7 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 KII83023.1 - 0.0038 16.8 5.7 0.0038 16.8 5.7 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII83023.1 - 0.011 15.9 0.5 0.041 14.1 0.5 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p450 PF00067.22 KII83024.1 - 2.4e-70 237.6 0.0 3e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KII83025.1 - 1.2e-38 133.0 0.6 4.6e-37 127.8 0.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII83025.1 - 1.1e-34 119.6 0.1 1.9e-34 118.8 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII83025.1 - 2.5e-06 27.5 0.2 5.4e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 KR domain F-box-like PF12937.7 KII83026.1 - 9.9e-13 47.8 0.8 3.7e-12 45.9 0.8 2.1 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.22 KII83027.1 - 5e-49 164.0 0.5 2.9e-17 62.2 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII83027.1 - 6.6e-09 35.5 0.0 0.034 14.0 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KII83027.1 - 6.8e-05 22.9 0.1 2.2 8.4 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif Suf PF05843.14 KII83027.1 - 0.0011 19.0 1.8 0.01 15.8 2.3 2.3 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) Nup35_RRM_2 PF14605.6 KII83027.1 - 0.0017 18.3 0.0 6.3 6.9 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KII83027.1 - 0.0047 17.2 6.2 1.8 8.7 0.0 4.1 5 0 0 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KII83027.1 - 0.0088 16.1 0.1 1.9 8.6 0.1 3.9 4 0 0 4 4 4 1 RNA binding motif UBA2_C PF16195.5 KII83027.1 - 0.02 15.5 1.8 0.068 13.9 1.8 2.0 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus TPR_14 PF13428.6 KII83027.1 - 3.9 8.5 6.3 20 6.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TENA_THI-4 PF03070.16 KII83028.1 - 1.2e-44 152.7 0.1 1.5e-44 152.3 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family p450 PF00067.22 KII83030.1 - 2.1e-67 227.9 0.0 2.6e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MRP-L47 PF06984.13 KII83031.1 - 2.4e-22 78.8 0.0 5.7e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KII83031.1 - 0.0032 17.4 3.8 0.0067 16.4 0.3 3.3 2 1 0 2 2 2 1 Ribosomal L29 protein Complex1_LYR PF05347.15 KII83032.1 - 2.1e-07 30.9 0.2 4e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KII83032.1 - 0.038 14.7 0.1 0.053 14.3 0.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like DUF2254 PF10011.9 KII83035.1 - 0.6 8.9 3.9 1 8.1 3.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Asp PF00026.23 KII83036.1 - 2.4e-07 30.5 0.0 0.022 14.2 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Salt_tol_Pase PF09506.10 KII83036.1 - 0.0004 19.3 0.0 0.49 9.1 0.0 2.1 2 0 0 2 2 2 2 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Asp PF00026.23 KII83037.1 - 5.3e-17 62.2 3.3 6.9e-17 61.8 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KII83037.1 - 0.00055 20.5 0.3 0.0013 19.3 0.3 1.6 1 1 0 1 1 1 1 Aspartyl protease TAXi_N PF14543.6 KII83037.1 - 0.00093 19.5 2.4 0.012 15.8 2.4 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Cu2_monooxygen PF01082.20 KII83038.1 - 0.016 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Tyrosinase PF00264.20 KII83039.1 - 4e-42 145.0 1.5 5.8e-42 144.5 1.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SPOC PF07744.13 KII83048.1 - 0.044 13.7 0.6 0.28 11.1 0.2 1.9 1 1 1 2 2 2 0 SPOC domain Tymo_coat PF00983.18 KII83048.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Tymovirus coat protein CxC2 PF18803.1 KII83049.1 - 3.4e-39 133.3 0.0 5.8e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII83049.1 - 1.9e-14 53.8 0.0 2.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83049.1 - 1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KII83049.1 - 0.02 14.7 0.7 0.072 12.9 0.0 2.1 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KII83051.1 - 5.4e-17 61.8 1.5 1.6e-13 50.7 0.4 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin YL1 PF05764.13 KII83052.1 - 0.6 10.2 14.0 0.28 11.3 1.6 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF1899 PF08953.11 KII83058.1 - 1.2e-26 92.3 0.1 3.3e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KII83058.1 - 3.1e-17 62.2 0.2 7.2e-17 61.0 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KII83058.1 - 1.3e-15 57.5 2.2 0.00036 21.3 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII83058.1 - 7.3e-05 23.0 0.0 0.19 12.1 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 KII83058.1 - 0.0051 17.1 0.3 0.0078 16.5 0.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 KII83058.1 - 0.17 12.3 2.7 0.31 11.5 2.7 1.3 1 0 0 1 1 1 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 KII83058.1 - 0.26 11.3 3.7 0.45 10.6 3.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rib_recp_KP_reg PF05104.12 KII83058.1 - 2 9.4 11.4 3.7 8.6 11.4 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region GcrA PF07750.11 KII83059.1 - 0.035 14.5 1.2 0.035 14.5 1.2 2.8 2 1 1 3 3 3 0 GcrA cell cycle regulator Nop14 PF04147.12 KII83059.1 - 4.3 5.4 14.2 7 4.7 14.2 1.3 1 0 0 1 1 1 0 Nop14-like family Peptidase_M28 PF04389.17 KII83063.1 - 4.3e-35 121.2 0.1 8.3e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Orexin_rec2 PF03827.13 KII83063.1 - 0.089 12.8 0.3 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Orexin receptor type 2 Peptidase_M20 PF01546.28 KII83063.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Cu-oxidase PF00394.22 KII83064.1 - 1.5e-48 164.9 0.0 9.2e-47 159.1 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII83064.1 - 7.1e-40 135.7 2.4 1.1e-38 131.8 0.3 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII83064.1 - 5.7e-34 116.8 5.5 4.1e-32 110.8 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase RRM_1 PF00076.22 KII83065.1 - 0.0003 20.5 0.0 0.00084 19.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RCC1 PF00415.18 KII83066.1 - 8.3e-18 64.7 0.4 0.0011 19.5 0.2 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KII83066.1 - 1.6e-13 50.8 0.0 2.3e-05 24.6 0.0 3.0 2 2 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KII83066.1 - 3.2e-09 37.1 0.6 8.1e-06 26.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII83066.1 - 5.8e-08 33.2 0.9 1.4e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KII83066.1 - 6.6e-08 32.2 11.3 8.4e-08 31.8 0.1 5.5 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 KII83066.1 - 4e-05 23.7 0.1 0.2 12.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KII83066.1 - 7.7e-05 22.9 0.5 0.15 12.4 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KII83066.1 - 0.00013 22.2 0.6 0.68 10.5 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat EKLF_TAD1 PF16832.5 KII83066.1 - 0.015 15.1 1.7 0.036 13.9 1.7 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Auxin_inducible PF02519.14 KII83067.1 - 0.0095 16.1 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Auxin responsive protein ADH_zinc_N PF00107.26 KII83068.1 - 1.2e-11 44.7 0.3 2.1e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII83068.1 - 3.2e-07 30.2 0.4 1.3e-06 28.2 0.3 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII83068.1 - 0.066 14.3 0.0 0.14 13.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-MYND PF01753.18 KII83069.1 - 2.1e-08 34.1 9.8 4.1e-08 33.2 9.8 1.4 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.18 KII83070.1 - 1.1e-20 73.8 0.0 2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII83070.1 - 8.9e-05 22.5 11.4 0.00015 21.8 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3094 PF11293.8 KII83070.1 - 0.067 12.9 0.1 0.23 11.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3094) HypA PF01155.19 KII83070.1 - 3.9 7.5 5.2 8 6.5 5.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fungal_trans PF04082.18 KII83074.1 - 5.8e-18 64.9 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII83074.1 - 7.9e-06 25.9 12.4 1.3e-05 25.2 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_4 PF07993.12 KII83075.1 - 7.6e-30 103.9 0.0 1.3e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII83075.1 - 6.4e-25 87.6 0.1 5.7e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII83075.1 - 6e-07 29.2 0.0 1.6e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KII83075.1 - 0.00077 19.8 0.2 0.0044 17.3 0.2 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site U62_UL91 PF17442.2 KII83075.1 - 0.076 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins NAD_binding_10 PF13460.6 KII83075.1 - 0.14 12.0 1.9 0.98 9.3 0.0 2.7 2 1 0 2 2 2 0 NAD(P)H-binding DUF3861 PF12977.7 KII83075.1 - 0.16 12.2 0.0 7.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) GDP_Man_Dehyd PF16363.5 KII83075.1 - 0.17 11.3 0.0 6.7 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fez1 PF06818.15 KII83077.1 - 0.021 15.3 12.5 0.13 12.7 10.6 2.3 1 1 1 2 2 2 0 Fez1 HalX PF08663.10 KII83077.1 - 0.041 14.2 0.0 0.041 14.2 0.0 6.4 5 2 1 6 6 6 0 HalX domain HMMR_N PF15905.5 KII83077.1 - 0.13 11.7 4.1 0.33 10.4 4.1 1.6 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HOOK PF05622.12 KII83077.1 - 0.14 10.3 9.4 0.15 10.2 2.6 2.2 2 0 0 2 2 2 0 HOOK protein Filament PF00038.21 KII83077.1 - 0.25 10.9 16.2 0.65 9.5 3.2 3.0 2 1 0 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 KII83077.1 - 0.26 10.1 16.5 0.52 9.1 2.3 3.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 KII83077.1 - 0.37 10.2 11.7 2.2 7.7 0.5 2.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 ATG16 PF08614.11 KII83077.1 - 0.59 10.3 24.2 12 6.0 11.3 3.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 KII83077.1 - 0.67 10.9 15.3 2.1 9.3 2.6 4.3 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain Lebercilin PF15619.6 KII83077.1 - 0.77 9.4 16.8 0.021 14.5 8.3 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RmuC PF02646.16 KII83077.1 - 1.3 8.1 5.5 4.3 6.4 1.3 2.8 3 0 0 3 3 3 0 RmuC family Apt1 PF10351.9 KII83077.1 - 1.3 7.8 3.5 2.1 7.1 3.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mto2_bdg PF12808.7 KII83077.1 - 1.5 9.2 19.0 0.41 11.0 1.4 4.2 4 0 0 4 4 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Cluap1 PF10234.9 KII83077.1 - 3.5 6.9 9.3 0.039 13.4 1.2 1.8 3 0 0 3 3 3 0 Clusterin-associated protein-1 GAS PF13851.6 KII83077.1 - 3.8 6.8 13.8 1.7 8.0 5.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.11 KII83078.1 - 0.0034 16.8 3.2 0.0034 16.8 3.2 2.2 1 1 0 2 2 2 1 Rabaptin-like protein Atg14 PF10186.9 KII83078.1 - 0.0072 15.5 7.7 0.017 14.2 7.7 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 KII83078.1 - 0.0076 14.9 4.9 0.0069 15.0 4.2 1.3 1 1 0 1 1 1 1 Macoilin family Leu_zip PF15294.6 KII83078.1 - 0.07 12.6 6.7 0.15 11.6 6.7 1.6 1 0 0 1 1 1 0 Leucine zipper Lebercilin PF15619.6 KII83078.1 - 0.66 9.6 14.0 1.2 8.8 1.0 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SPATA1_C PF15743.5 KII83078.1 - 2.6 8.1 10.4 73 3.4 8.5 2.9 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Fez1 PF06818.15 KII83078.1 - 4.1 7.8 12.1 1.5e+02 2.7 12.1 2.2 1 1 0 1 1 1 0 Fez1 DivIC PF04977.15 KII83078.1 - 6.8 6.5 13.0 1.9 8.3 0.3 4.0 3 1 1 4 4 4 0 Septum formation initiator YabA PF06156.13 KII83078.1 - 7.5 7.3 5.3 29 5.4 1.2 2.8 1 1 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KII83078.1 - 9.3 6.3 14.3 5.7 7.0 1.0 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_integrase PF00589.22 KII83079.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family zf-H2C2_5 PF13909.6 KII83081.1 - 0.00055 19.6 0.2 0.0016 18.2 0.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KII83081.1 - 0.048 14.5 0.6 0.15 13.0 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Tet_JBP PF12851.7 KII83082.1 - 1.3e-06 28.1 0.0 2.3e-06 27.2 0.0 1.4 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily GP46 PF07409.12 KII83084.1 - 0.29 10.9 3.3 0.55 10.0 0.1 2.7 3 0 0 3 3 3 0 Phage protein GP46 RVP_2 PF08284.11 KII83085.1 - 1.4e-07 31.4 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KII83085.1 - 0.00016 22.3 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KII83085.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KII83085.1 - 0.092 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease BAALC_N PF06989.12 KII83085.1 - 0.13 12.5 0.3 50 4.3 0.0 3.0 3 0 0 3 3 3 0 BAALC N-terminus Zn_clus PF00172.18 KII83088.1 - 3.6 7.8 10.7 4 7.7 3.7 2.0 1 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain KDZ PF18758.1 KII83090.1 - 4.1e-41 141.0 0.0 7.6e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83090.1 - 1.4e-25 89.6 0.1 3.2e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII83090.1 - 0.00052 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 KII83092.1 - 7.2e-06 25.6 0.0 1.5e-05 24.5 0.0 1.5 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Myb_DNA-binding PF00249.31 KII83094.1 - 0.049 13.8 2.6 5.1 7.4 0.0 2.9 3 1 0 3 3 3 0 Myb-like DNA-binding domain Herpes_capsid PF06112.11 KII83094.1 - 0.05 13.7 1.2 0.087 12.9 1.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RinB PF06116.12 KII83094.1 - 0.15 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional activator RinB zf-C2H2_12 PF18658.1 KII83096.1 - 0.67 9.6 3.5 1.7 8.3 3.1 1.9 1 1 0 1 1 1 0 Zinc-finger C2H2-type SR-25 PF10500.9 KII83100.1 - 0.0017 18.0 17.8 0.0034 17.0 17.8 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dsh_C PF12316.8 KII83100.1 - 0.06 13.8 3.6 0.082 13.3 3.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 KII83100.1 - 0.18 10.1 24.2 0.043 12.1 20.9 1.5 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.13 KII83100.1 - 0.26 11.4 26.7 0.022 14.9 22.1 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Dehydrin PF00257.19 KII83100.1 - 0.71 10.4 13.1 1.1 9.8 13.1 1.3 1 0 0 1 1 1 0 Dehydrin RR_TM4-6 PF06459.12 KII83100.1 - 1.4 8.7 12.8 2.3 8.0 12.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 KII83100.1 - 1.6 5.8 6.5 1.9 5.5 6.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GrpE PF01025.19 KII83100.1 - 1.9 8.2 11.6 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 GrpE RNA_pol_Rpc4 PF05132.14 KII83100.1 - 3.1 8.2 10.1 5.8 7.3 10.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 KII83100.1 - 3.7 7.0 10.1 7.9 5.9 10.1 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 KII83100.1 - 5.4 5.0 27.4 2.5 6.1 23.5 1.9 2 0 0 2 2 2 0 DNA polymerase phi TFIIE-A_C PF11521.8 KII83100.1 - 5.7 7.3 14.3 2.4 8.5 10.8 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Atrophin-1 PF03154.15 KII83100.1 - 8.7 4.5 12.0 11 4.1 12.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family EOS1 PF12326.8 KII83102.1 - 0.016 15.1 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 N-glycosylation protein PBP1_TM PF14812.6 KII83102.1 - 0.02 15.2 3.7 0.035 14.5 3.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RPN2_C PF18004.1 KII83102.1 - 0.12 12.2 6.2 0.15 11.9 6.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 KII83102.1 - 0.15 11.5 8.0 0.16 11.4 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Connexin PF00029.19 KII83102.1 - 0.19 11.5 1.3 0.22 11.3 1.3 1.1 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 KII83102.1 - 0.22 10.4 0.4 0.26 10.2 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DNA_pol_phi PF04931.13 KII83102.1 - 0.3 9.2 9.8 0.33 9.0 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KII83102.1 - 0.35 10.5 8.0 0.47 10.1 8.0 1.2 1 0 0 1 1 1 0 FAM176 family FancD2 PF14631.6 KII83102.1 - 0.46 7.8 2.1 0.5 7.7 2.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 KII83102.1 - 0.53 10.1 8.9 0.58 9.9 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KII83102.1 - 0.57 9.1 1.8 0.58 9.1 1.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nucleo_P87 PF07267.11 KII83102.1 - 0.76 8.6 7.2 0.83 8.4 7.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KII83102.1 - 0.95 7.7 10.2 0.98 7.6 10.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KII83102.1 - 0.97 7.6 13.3 0.99 7.5 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 KII83102.1 - 1.3 8.3 5.7 1.5 8.1 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pox_Ag35 PF03286.14 KII83102.1 - 1.5 8.5 10.0 1.7 8.4 10.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GEN1_C PF18380.1 KII83102.1 - 1.6 9.7 10.2 2.9 8.8 10.2 1.5 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain TRAP_alpha PF03896.16 KII83102.1 - 1.7 7.8 5.5 1.9 7.6 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.8 KII83102.1 - 2 8.6 14.2 2.2 8.5 14.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIF_alpha PF05793.12 KII83102.1 - 2.2 6.8 16.8 2.3 6.7 16.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MCM_bind PF09739.9 KII83102.1 - 2.3 6.6 4.6 2.6 6.4 4.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 KII83102.1 - 2.6 6.7 6.6 2.9 6.6 6.6 1.1 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 KII83102.1 - 3.3 7.2 8.8 3.9 7.0 8.8 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Myc_N PF01056.18 KII83102.1 - 3.3 7.5 9.0 3.6 7.4 9.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NPR3 PF03666.13 KII83102.1 - 3.8 6.2 7.0 3.9 6.2 7.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 KII83102.1 - 7.5 4.3 5.4 7.9 4.2 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 KII83102.1 - 9 5.4 6.0 9.3 5.4 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MAP17 PF15807.5 KII83102.1 - 9.6 6.5 9.0 12 6.1 9.0 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 His_Phos_1 PF00300.22 KII83103.1 - 0.07 12.8 2.1 0.47 10.1 0.2 2.6 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DEC-1_N PF04625.13 KII83104.1 - 0.14 11.1 4.4 0.13 11.2 4.4 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4413 PF14372.6 KII83106.1 - 0.00019 21.8 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KII83107.1 - 3.4e-14 52.4 0.1 4.1e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region US30 PF17624.2 KII83108.1 - 0.0086 15.2 0.9 0.019 14.0 0.9 1.6 1 0 0 1 1 1 1 Family of unknown function Tudor-knot PF11717.8 KII83116.1 - 0.0056 16.6 1.2 0.012 15.5 1.2 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KII83116.1 - 0.19 11.7 6.0 0.37 10.7 6.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Dynamin_N PF00350.23 KII83118.1 - 0.00084 19.4 0.0 0.0025 17.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family FlaC_arch PF05377.11 KII83120.1 - 0.028 14.8 0.9 0.048 14.1 0.9 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KII83120.1 - 0.037 14.0 1.2 0.037 14.0 1.2 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SSFA2_C PF14723.6 KII83120.1 - 0.04 13.8 0.3 0.055 13.4 0.3 1.2 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF2570 PF10828.8 KII83120.1 - 0.057 13.2 0.4 0.092 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DivIC PF04977.15 KII83120.1 - 0.13 12.1 0.9 0.24 11.2 0.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Csm1_N PF18504.1 KII83120.1 - 0.13 12.6 2.3 0.33 11.3 2.3 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Prominin PF05478.11 KII83120.1 - 0.13 10.2 0.1 0.16 9.9 0.1 1.0 1 0 0 1 1 1 0 Prominin F-box PF00646.33 KII83121.1 - 3e-06 27.0 0.0 8.6e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII83121.1 - 0.096 12.6 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like Interferon PF00143.19 KII83122.1 - 0.23 11.6 0.0 0.28 11.3 0.0 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain NUP50 PF08911.11 KII83125.1 - 0.0028 18.3 0.1 0.0068 17.0 0.1 1.7 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Dimer_Tnp_hAT PF05699.14 KII83130.1 - 8.4e-10 38.3 0.2 9.1e-10 38.2 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rsc14 PF08586.10 KII83132.1 - 0.02 15.7 0.0 0.041 14.7 0.0 1.5 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit JmjC PF02373.22 KII83135.1 - 6e-11 42.8 0.0 6e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KII83135.1 - 0.044 13.5 0.1 0.12 12.0 0.1 1.9 1 1 0 1 1 1 0 Cupin-like domain Cupin_2 PF07883.11 KII83135.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Cupin domain CBFD_NFYB_HMF PF00808.23 KII83137.1 - 3.3e-08 33.7 0.4 7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII83137.1 - 3.2e-05 24.3 0.2 0.00017 22.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KII83137.1 - 0.018 15.2 0.1 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TAFII28 PF04719.14 KII83137.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Bromo_TP PF07524.13 KII83137.1 - 0.048 13.7 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated ANAPC_CDC26 PF10471.9 KII83137.1 - 0.057 14.2 2.8 0.17 12.8 2.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Zn_clus PF00172.18 KII83141.1 - 4.9e-05 23.4 8.9 0.00012 22.2 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.31 KII83142.1 - 0.00011 22.5 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII83144.1 - 1.2e-07 31.7 0.0 1.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KII83144.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 KII83144.1 - 0.069 13.1 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M28 PF04389.17 KII83145.1 - 0.066 12.9 0.1 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M28 YL1 PF05764.13 KII83146.1 - 0.01 16.0 16.5 0.017 15.3 16.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Tub_N PF16322.5 KII83146.1 - 0.019 15.4 9.0 0.026 14.9 9.0 1.2 1 0 0 1 1 1 0 Tubby N-terminal CDC45 PF02724.14 KII83146.1 - 0.088 11.1 17.4 0.11 10.7 17.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BSMAP PF12280.8 KII83146.1 - 2.8 8.1 5.0 4.8 7.3 5.0 1.4 1 1 0 1 1 1 0 Brain specific membrane anchored protein DNA_pol_phi PF04931.13 KII83146.1 - 6.5 4.7 20.1 10 4.1 20.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4484 PF14831.6 KII83146.1 - 9 6.3 10.9 15 5.5 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RVP PF00077.20 KII83147.1 - 0.031 14.6 0.0 0.068 13.5 0.0 1.5 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.10 KII83147.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 KII83147.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Dimer_Tnp_hAT PF05699.14 KII83154.1 - 1.1e-06 28.4 0.2 1.4e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Tet_JBP PF12851.7 KII83157.1 - 3.6e-07 29.8 0.0 8.5e-06 25.3 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily KDZ PF18758.1 KII83158.1 - 3.5e-38 131.4 0.4 6.3e-38 130.6 0.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83158.1 - 2.8e-24 85.3 4.8 1.1e-23 83.4 1.4 2.6 2 1 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII83158.1 - 0.0017 18.5 0.1 0.0046 17.1 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases MbeD_MobD PF04899.12 KII83158.1 - 0.13 12.4 0.5 0.8 9.9 0.4 2.3 2 0 0 2 2 2 0 MbeD/MobD like CheZ PF04344.13 KII83158.1 - 0.92 9.4 5.0 0.28 11.1 1.5 1.9 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ Retrotran_gag_2 PF14223.6 KII83159.1 - 5e-07 29.5 0.0 7.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII83159.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KII83159.1 - 0.1 12.3 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DEAD PF00270.29 KII83164.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII83164.1 - 1.8e-10 41.1 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KII83164.1 - 0.13 11.4 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GHMP_kinases_N PF00288.26 KII83165.1 - 7.8e-10 38.9 1.6 7.8e-10 38.9 1.6 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KII83165.1 - 0.00035 20.9 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Ferrochelatase PF00762.19 KII83166.1 - 3.7e-32 111.7 0.1 8.3e-14 51.4 0.0 3.9 2 2 2 4 4 4 4 Ferrochelatase VHS PF00790.19 KII83166.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 VHS domain Helicase_C PF00271.31 KII83167.1 - 6.2e-10 39.4 0.0 3.7e-09 36.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII83167.1 - 2.4e-06 27.4 0.0 5.8e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KII83167.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Tet_JBP PF12851.7 KII83173.1 - 3.6e-06 26.6 0.0 1.5e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Plavaka PF18759.1 KII83174.1 - 1.2e-50 172.6 0.0 2e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Kelch_4 PF13418.6 KII83176.1 - 9.9e-10 38.3 4.4 6.3e-06 26.1 0.2 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KII83176.1 - 3.6e-08 33.5 5.4 0.00043 20.5 0.8 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KII83176.1 - 2.6e-07 30.1 2.3 0.00015 21.3 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KII83176.1 - 5.1e-07 29.8 0.6 0.0023 18.2 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KII83176.1 - 1.1e-06 28.5 0.3 0.18 11.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KII83176.1 - 9.7e-05 22.2 1.4 2 8.5 0.0 3.8 4 0 0 4 4 4 2 Kelch motif DUF4926 PF16277.5 KII83179.1 - 0.025 13.9 0.2 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4926) Plavaka PF18759.1 KII83180.1 - 3.8e-18 65.8 1.6 3.8e-18 65.8 1.6 1.6 2 0 0 2 2 2 1 Plavaka transposase Plavaka PF18759.1 KII83181.1 - 4.2e-33 115.0 0.1 5e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 KII83184.1 - 0.00038 20.0 29.0 0.00048 19.7 29.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KII83184.1 - 0.0014 16.9 30.5 0.0019 16.6 30.5 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KII83184.1 - 0.019 13.3 24.5 0.022 13.1 24.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 KII83184.1 - 3 6.9 17.0 3.7 6.5 17.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Merozoite_SPAM PF07133.11 KII83184.1 - 4.3 7.3 32.7 7.3 6.5 32.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Astro_capsid_p PF12226.8 KII83184.1 - 10 5.2 28.4 15 4.6 28.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Acetyltransf_3 PF13302.7 KII83185.1 - 0.0034 18.1 0.1 0.0037 17.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SnoaL_2 PF12680.7 KII83185.1 - 0.012 16.2 0.2 0.015 15.9 0.2 1.2 1 0 0 1 1 1 0 SnoaL-like domain Acetyltransf_1 PF00583.25 KII83186.1 - 7.2e-08 32.7 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KII83186.1 - 3.9e-05 24.4 0.0 0.00014 22.5 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII83186.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p47_phox_C PF08944.11 KII83188.1 - 0.055 12.9 0.1 0.16 11.4 0.1 1.8 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Acetyltransf_3 PF13302.7 KII83190.1 - 0.0033 18.1 0.0 0.0094 16.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain YL1 PF05764.13 KII83191.1 - 0.027 14.6 0.1 0.027 14.6 0.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF4611 PF15387.6 KII83191.1 - 1.8 8.8 12.5 1.5 9.1 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 KII83191.1 - 6.8 6.4 11.4 4.6 7.0 3.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRM_1 PF00076.22 KII83192.1 - 2.6e-15 56.0 0.2 4.3e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KII83193.1 - 9e-21 73.8 0.3 1.7e-20 72.9 0.3 1.4 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Integrase_H2C2 PF17921.1 KII83194.1 - 0.00062 19.8 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 KII83196.1 - 0.026 15.1 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII83196.1 - 0.08 13.6 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 KII83197.1 - 2.4e-05 24.2 1.9 7.9e-05 22.6 1.9 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KII83197.1 - 0.0057 16.3 2.8 0.016 14.9 2.8 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KII83197.1 - 0.031 14.1 1.1 0.059 13.2 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 KII83197.1 - 0.052 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1631 PF07793.11 KII83197.1 - 0.26 9.7 2.2 2.3 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Retrotran_gag_3 PF14244.6 KII83198.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NACHT_N PF17100.5 KII83198.1 - 0.065 13.1 0.1 0.078 12.8 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase gag_pre-integrs PF13976.6 KII83199.1 - 2.7e-07 30.4 0.1 4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain LEA_6 PF10714.9 KII83201.1 - 0.16 12.0 3.5 1.1 9.4 0.4 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Peptidase_C48 PF02902.19 KII83205.1 - 6.8e-09 35.9 0.3 6.9e-09 35.9 0.3 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KDZ PF18758.1 KII83206.1 - 1.2e-49 168.9 0.0 2.5e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83206.1 - 4.4e-07 30.0 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII83206.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Zn_clus PF00172.18 KII83207.1 - 0.0001 22.3 8.9 0.0001 22.3 8.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gyro_capsid PF04162.12 KII83208.1 - 0.0078 14.8 0.3 0.012 14.1 0.3 1.2 1 0 0 1 1 1 1 Gyrovirus capsid protein (VP1) Ecl1 PF12855.7 KII83208.1 - 0.17 13.0 32.4 0.072 14.2 14.3 4.2 2 1 1 3 3 3 0 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KII83211.1 - 6.2e-10 39.0 10.1 2.9e-09 36.9 10.5 1.8 1 1 1 2 2 2 1 MYND finger adh_short PF00106.25 KII83213.1 - 3.8e-12 46.1 0.4 3.9e-12 46.0 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII83213.1 - 3.6e-08 33.3 0.6 3.7e-08 33.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII83213.1 - 1.9e-05 24.7 0.2 2.1e-05 24.5 0.2 1.0 1 0 0 1 1 1 1 KR domain DUF2149 PF09919.9 KII83214.1 - 2 8.7 3.5 1.5 9.2 0.7 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Fer4_6 PF12837.7 KII83219.1 - 0.12 12.4 0.7 0.31 11.2 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain KDZ PF18758.1 KII83222.1 - 1.2e-44 152.6 0.0 2.2e-22 79.8 0.0 2.2 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83222.1 - 5.5e-39 132.6 0.0 9.3e-39 131.9 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII83222.1 - 9.5e-08 32.1 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KII83222.1 - 0.11 12.3 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases IBR PF01485.21 KII83222.1 - 3.1 8.1 7.4 8.7 6.7 7.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 KII83222.1 - 6.9 6.9 7.9 17 5.6 7.9 1.7 1 0 0 1 1 1 0 B-box zinc finger 2OG-FeII_Oxy_3 PF13640.6 KII83223.1 - 0.12 13.3 0.0 0.2 12.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Toxin_7 PF05980.12 KII83224.1 - 0.0081 16.4 3.7 0.019 15.2 3.7 1.6 1 0 0 1 1 1 1 Toxin 7 Toxin_35 PF10530.9 KII83224.1 - 0.038 14.0 1.0 0.062 13.3 1.0 1.3 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold UPF0506 PF11703.8 KII83224.1 - 0.15 12.5 3.8 0.25 11.8 3.8 1.4 1 0 0 1 1 1 0 UPF0506 Toxin_12 PF07740.12 KII83224.1 - 0.22 12.2 3.6 0.44 11.3 3.6 1.6 1 0 0 1 1 1 0 Ion channel inhibitory toxin Sigma70_r1_1 PF03979.14 KII83225.1 - 0.46 10.6 5.9 0.91 9.6 5.9 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Aldedh PF00171.22 KII83226.1 - 1.6e-84 284.1 0.0 2e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MukB_hinge PF16330.5 KII83226.1 - 0.0074 16.0 0.3 0.069 12.9 0.3 2.1 2 0 0 2 2 2 1 MukB hinge domain LuxC PF05893.14 KII83226.1 - 0.034 13.2 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) ICMT PF04140.14 KII83227.1 - 7.6e-14 51.9 1.1 1e-13 51.5 0.1 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII83227.1 - 6.9e-12 45.7 3.3 2.1e-11 44.1 0.9 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII83227.1 - 0.022 13.6 0.2 0.034 12.9 0.2 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DAHP_synth_2 PF01474.16 KII83228.1 - 1e-197 657.0 0.0 1.2e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HECT PF00632.25 KII83229.1 - 8.4e-95 317.8 0.0 1.3e-94 317.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KII83229.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Mito_carr PF00153.27 KII83230.1 - 8e-27 93.0 4.5 5e-14 52.0 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.21 KII83231.1 - 2.6e-27 95.3 0.2 3.3e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BRK PF07533.16 KII83235.1 - 0.17 11.6 0.3 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 BRK domain MFS_1 PF07690.16 KII83239.1 - 1.3e-21 76.9 37.2 7.3e-21 74.5 36.4 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_92 PF07971.12 KII83240.1 - 5.9e-118 394.7 0.0 6.9e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KII83240.1 - 1.8e-35 123.0 0.5 3e-35 122.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain G-patch_2 PF12656.7 KII83241.1 - 2.1e-22 79.0 0.0 5.7e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 G-patch domain Fe-S_biosyn PF01521.20 KII83242.1 - 6.7e-07 29.5 0.0 1e-06 28.9 0.0 1.4 1 1 1 2 2 2 1 Iron-sulphur cluster biosynthesis PTPS PF01242.19 KII83242.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Acetyltransf_1 PF00583.25 KII83243.1 - 0.00045 20.4 0.1 0.00084 19.6 0.0 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII83243.1 - 0.0072 16.7 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KII83243.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Peptidase_S10 PF00450.22 KII83244.1 - 4.5e-112 375.5 0.0 5.5e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Dicty_CTDC PF00526.18 KII83245.1 - 0.33 10.9 1.2 0.56 10.2 1.2 1.3 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat DUF3682 PF12446.8 KII83249.1 - 0.019 15.4 6.6 0.026 15.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) NOA36 PF06524.12 KII83249.1 - 4 6.7 11.7 4.3 6.6 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KII83249.1 - 9.3 4.4 11.0 9.4 4.4 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein HTH_23 PF13384.6 KII83250.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KII83250.1 - 0.0075 16.9 0.1 0.014 16.0 0.1 1.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KII83250.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KII83250.1 - 0.027 14.6 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Cauli_VI PF01693.16 KII83253.1 - 1.1e-19 70.4 0.2 2e-08 34.4 0.0 3.2 3 0 0 3 3 3 3 Caulimovirus viroplasmin PRCC PF10253.9 KII83253.1 - 0.16 12.7 4.3 0.24 12.2 4.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting KDZ PF18758.1 KII83256.1 - 3e-51 174.2 0.0 4.3e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83256.1 - 1.9e-38 130.9 0.0 3.6e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII83256.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KII83256.1 - 0.087 12.7 0.0 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases ArfGap PF01412.18 KII83256.1 - 1.3 9.2 5.8 3.4 7.8 5.8 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-B_box PF00643.24 KII83256.1 - 3.3 7.9 6.8 7.9 6.7 6.8 1.6 1 0 0 1 1 1 0 B-box zinc finger TPR_10 PF13374.6 KII83258.1 - 7.5e-58 191.0 2.3 1.8e-07 30.8 0.0 9.2 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 KII83258.1 - 6.2e-54 180.2 4.8 8.2e-13 48.4 0.1 7.7 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KII83258.1 - 9.3e-23 78.5 5.2 0.058 13.4 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 KII83258.1 - 4.1e-17 61.2 19.5 0.17 11.7 0.1 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 KII83258.1 - 5.3e-14 51.1 16.3 1.1 9.5 0.0 8.3 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_4 PF07721.14 KII83258.1 - 1.5e-13 49.9 0.0 1.5 9.7 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII83258.1 - 8.6e-12 44.3 20.5 0.57 10.5 0.7 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KII83258.1 - 3.8e-11 42.6 13.4 1.8 9.2 0.0 8.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII83258.1 - 7e-11 42.5 11.3 0.62 10.6 0.2 7.2 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII83258.1 - 1.1e-10 42.0 0.6 2.4 8.9 0.0 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KII83258.1 - 9e-10 38.4 14.8 0.0012 18.3 0.5 3.7 1 1 1 3 3 3 3 MalT-like TPR region ANAPC3 PF12895.7 KII83258.1 - 1.3e-08 34.9 9.0 0.42 10.9 0.1 5.8 2 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KII83258.1 - 2.4e-08 34.1 6.8 3.1 8.9 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 KII83258.1 - 1.4e-05 25.3 8.7 2.4 8.5 0.2 5.2 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.12 KII83258.1 - 1.6e-05 24.8 12.2 0.53 10.3 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 KII83258.1 - 0.0013 18.9 10.2 20 5.7 0.1 7.5 9 0 0 9 9 8 0 PPR repeat HHH_3 PF12836.7 KII83258.1 - 0.047 14.0 2.1 12 6.2 0.0 4.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif DUF4404 PF14357.6 KII83258.1 - 0.077 13.6 5.7 11 6.7 0.1 4.8 2 2 3 5 5 5 0 Domain of unknown function (DUF4404) TPR_9 PF13371.6 KII83258.1 - 0.082 13.1 0.1 8.9 6.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Octopine_DH PF02317.17 KII83258.1 - 0.13 12.3 0.0 9.8 6.2 0.0 3.1 2 1 1 4 4 4 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain BOFC_N PF08977.10 KII83258.1 - 0.14 12.2 0.1 4.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Bypass of Forespore C, N terminal Alkyl_sulf_dimr PF14863.6 KII83258.1 - 0.17 12.4 4.3 7.3 7.1 0.0 3.5 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 KII83258.1 - 0.52 11.1 9.6 83 4.2 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII83258.1 - 1.4 8.6 9.3 60 3.4 0.0 6.1 7 1 1 8 8 8 0 TPR repeat DUF4477 PF14780.6 KII83258.1 - 2.8 7.5 7.4 2.2 7.9 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4477) Patatin PF01734.22 KII83259.1 - 1.9e-17 64.2 0.0 1.1e-15 58.3 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Oxidored_FMN PF00724.20 KII83260.1 - 1.5e-102 343.3 0.0 1.8e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII83261.1 - 1.6e-14 54.0 0.0 1.8e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII83262.1 - 1.1e-47 162.9 0.0 1.3e-47 162.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII83263.1 - 7.5e-95 318.1 0.0 8.6e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.7 KII83264.1 - 7.1e-10 38.6 2.0 7.1e-10 38.6 2.0 1.8 2 0 0 2 2 2 1 F-box-like Apolipoprotein PF01442.18 KII83264.1 - 0.089 12.7 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TMF_TATA_bd PF12325.8 KII83264.1 - 0.1 12.8 0.1 0.14 12.4 0.1 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box PF00646.33 KII83264.1 - 0.12 12.3 3.9 1.6 8.7 0.5 2.6 2 0 0 2 2 2 0 F-box domain Oxidored_FMN PF00724.20 KII83265.1 - 2.9e-99 332.6 0.0 3.3e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII83266.1 - 1.2e-98 330.6 0.0 1.4e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII83267.1 - 5.1e-101 338.4 0.0 5.8e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Insulin_TMD PF17870.1 KII83268.1 - 0.11 12.6 0.8 0.11 12.6 0.8 3.1 4 0 0 4 4 4 0 Insulin receptor trans-membrane segment NTP_transferase PF00483.23 KII83271.1 - 2.2e-42 145.4 0.0 5.5e-42 144.1 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KII83271.1 - 1e-06 29.2 0.3 2.3e-06 28.1 0.3 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 KII83271.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CCDC92 PF14916.6 KII83271.1 - 0.081 12.7 0.2 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ADH_zinc_N PF00107.26 KII83272.1 - 5.9e-17 61.9 0.0 9.7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII83272.1 - 5.6e-16 59.8 0.0 1e-15 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII83272.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DTHCT PF08070.11 KII83273.1 - 1.1 10.0 14.5 1.1 10.1 13.4 1.5 1 1 0 1 1 1 0 DTHCT (NUC029) region S_4TM PF18159.1 KII83274.1 - 0.025 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Nucleoporin_FG2 PF15967.5 KII83275.1 - 1.1 7.7 9.3 1.2 7.5 9.3 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region Baculo_F PF12259.8 KII83277.1 - 0.016 13.8 0.0 0.018 13.6 0.0 1.0 1 0 0 1 1 1 0 Baculovirus F protein DUF3668 PF12416.8 KII83277.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Cep120 protein Apolipoprotein PF01442.18 KII83278.1 - 0.0081 16.1 20.4 0.02 14.8 20.4 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 KII83278.1 - 1.9 8.2 12.5 2.6 7.8 12.5 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B F-box PF00646.33 KII83284.1 - 0.00043 20.1 0.2 0.0014 18.4 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII83284.1 - 0.054 13.4 1.1 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 F-box-like ATPase-cat_bd PF12156.8 KII83284.1 - 0.08 13.7 2.3 0.24 12.1 2.3 1.8 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase UBA2_C PF16195.5 KII83284.1 - 6.9 7.4 6.9 2.3 9.0 3.2 2.1 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Beta-lactamase PF00144.24 KII83285.1 - 1.2e-41 143.1 1.1 7.4e-41 140.5 1.1 1.8 1 1 0 1 1 1 1 Beta-lactamase tRNA_int_end_N2 PF12928.7 KII83286.1 - 2.7e-22 78.7 0.0 4.6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KII83286.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain HMG_box PF00505.19 KII83287.1 - 1e-13 51.5 1.1 1.3e-13 51.1 1.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII83287.1 - 1.8e-08 34.8 0.3 2.2e-08 34.5 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain GIT_SHD PF08518.11 KII83288.1 - 0.00011 21.7 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 Spa2 homology domain (SHD) of GIT FAD_binding_2 PF00890.24 KII83289.1 - 9.5e-85 285.2 2.2 1.1e-84 285.0 2.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII83289.1 - 6.1e-17 62.2 0.3 9.5e-17 61.6 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII83289.1 - 2.4e-10 40.2 0.6 1.4e-08 34.4 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII83289.1 - 6.4e-10 39.1 3.2 1.2e-09 38.3 0.3 3.0 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KII83289.1 - 5.1e-09 36.0 0.3 9.4e-09 35.1 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII83289.1 - 3.5e-07 29.8 0.1 5.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KII83289.1 - 9.3e-06 24.6 4.8 0.00029 19.7 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KII83289.1 - 7.2e-05 22.0 4.3 0.00082 18.6 0.8 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 KII83289.1 - 0.00017 20.9 2.7 0.086 12.1 0.8 2.6 2 0 0 2 2 2 2 Thi4 family Amino_oxidase PF01593.24 KII83289.1 - 0.00029 20.2 2.0 0.0019 17.6 0.3 2.5 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KII83289.1 - 0.00092 18.6 0.7 0.28 10.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KII83289.1 - 0.0023 17.2 0.6 0.005 16.2 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KII83289.1 - 0.0081 16.7 0.8 0.12 12.9 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII83289.1 - 0.0095 15.9 0.5 1.3 8.9 0.3 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KII83289.1 - 0.012 14.6 0.2 0.027 13.6 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KII83289.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PilJ PF13675.6 KII83293.1 - 0.025 14.6 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nnf1 PF03980.14 KII83293.1 - 0.071 13.5 1.4 0.15 12.4 1.4 1.5 1 0 0 1 1 1 0 Nnf1 FAD_binding_2 PF00890.24 KII83294.1 - 2.6e-86 290.3 1.0 3.3e-86 290.0 1.0 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KII83294.1 - 1.3e-22 79.7 0.0 3.7e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KII83294.1 - 2.8e-16 60.0 0.1 4.1e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII83294.1 - 5.4e-11 42.3 1.7 8.4e-09 35.1 0.2 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII83294.1 - 1.6e-10 41.0 0.8 9.8e-10 38.5 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KII83294.1 - 8.1e-10 38.6 0.3 1.3e-09 37.9 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII83294.1 - 2.3e-07 30.4 0.1 3.7e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KII83294.1 - 2.1e-06 27.1 2.6 8.4e-05 21.8 0.8 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 KII83294.1 - 4.6e-06 25.6 4.4 0.00012 20.9 0.6 3.0 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KII83294.1 - 7.3e-05 22.2 2.4 0.00085 18.7 0.4 2.8 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KII83294.1 - 7.8e-05 22.0 1.2 0.016 14.4 0.3 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KII83294.1 - 0.00019 20.8 1.1 0.23 10.7 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KII83294.1 - 0.00031 20.1 0.6 0.00063 19.1 0.6 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KII83294.1 - 0.0037 17.8 1.1 0.066 13.8 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII83294.1 - 0.0076 16.2 0.7 1.9 8.5 0.4 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KII83294.1 - 0.023 13.8 0.4 0.044 12.8 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KII83294.1 - 0.032 14.6 0.0 0.058 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_M19 PF01244.21 KII83295.1 - 6.6e-106 354.1 0.0 8e-106 353.8 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF883 PF05957.13 KII83296.1 - 0.91 10.2 6.1 4.4 8.0 1.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) XG_FTase PF03254.13 KII83298.1 - 0.08 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase DUF883 PF05957.13 KII83298.1 - 2 9.1 6.7 3.3 8.4 1.8 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ArAE_2 PF10334.9 KII83301.1 - 1.2e-16 61.3 0.1 1.4e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 Beta-lactamase PF00144.24 KII83304.1 - 1.6e-45 155.8 0.2 2.9e-45 154.9 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase AAA_18 PF13238.6 KII83305.1 - 8.9e-05 23.0 0.0 0.0026 18.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII83305.1 - 0.002 18.3 0.1 0.006 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KII83305.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KII83305.1 - 0.048 14.0 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KII83305.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KII83305.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DDE_1 PF03184.19 KII83307.1 - 2.9e-05 23.8 0.0 4.2e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-SNAP50_C PF12251.8 KII83311.1 - 0.045 13.4 0.1 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal F-box-like PF12937.7 KII83315.1 - 0.0032 17.3 1.5 0.0059 16.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII83316.1 - 1.5e-05 24.8 0.0 3.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII83316.1 - 0.00079 19.2 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF4449 PF14613.6 KII83317.1 - 1.3e-36 126.1 0.3 1.3e-36 126.1 0.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) SF3A3 PF16837.5 KII83317.1 - 0.057 13.9 0.3 0.12 12.9 0.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Ank_4 PF13637.6 KII83319.1 - 7.7e-19 67.8 0.2 1.2e-09 38.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII83319.1 - 1.7e-14 54.2 0.0 2e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KII83319.1 - 7e-14 51.6 3.2 2.7e-05 24.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KII83319.1 - 3e-13 48.7 0.1 0.00069 19.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KII83319.1 - 2.4e-11 43.7 0.2 0.00017 21.8 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Sod_Fe_C PF02777.18 KII83320.1 - 1.8e-33 114.8 0.0 3.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KII83320.1 - 8.9e-33 112.6 3.4 1.9e-32 111.6 2.6 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GRP PF07172.11 KII83321.1 - 0.097 13.4 21.9 0.16 12.7 5.1 2.9 3 0 0 3 3 3 0 Glycine rich protein family IFT57 PF10498.9 KII83321.1 - 0.21 10.6 5.3 0.3 10.0 5.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MscS_porin PF12795.7 KII83321.1 - 0.27 10.7 17.0 1.3 8.5 17.0 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Exonuc_VII_L PF02601.15 KII83321.1 - 1.4 8.4 9.1 2.3 7.7 9.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3602 PF12223.8 KII83323.1 - 5e-13 49.5 20.3 1.4e-09 38.4 3.0 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) GATA PF00320.27 KII83324.1 - 1 9.1 3.4 5.7 6.6 0.3 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-RRN7 PF11781.8 KII83324.1 - 1.2 8.9 3.7 0.84 9.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-MYND PF01753.18 KII83325.1 - 4.2e-09 36.4 9.4 8.6e-09 35.3 9.4 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII83325.1 - 0.024 14.9 5.0 0.05 13.9 5.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding eIF3g PF12353.8 KII83327.1 - 0.022 15.1 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 KII83327.1 - 0.057 13.1 2.6 0.12 12.1 2.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SH3_9 PF14604.6 KII83328.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII83328.1 - 0.002 17.7 0.0 0.0048 16.5 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KII83328.1 - 0.034 13.8 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Neisseria_TspB PF05616.13 KII83328.1 - 2.5 6.5 11.8 3.8 5.9 11.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2568 PF10823.8 KII83331.1 - 0.055 13.7 1.7 0.16 12.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) DUF4835 PF16119.5 KII83332.1 - 0.062 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) F-box PF00646.33 KII83333.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII83333.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like MASE3 PF17159.4 KII83334.1 - 0.0092 15.6 0.3 0.021 14.5 0.3 1.5 1 0 0 1 1 1 1 Membrane-associated sensor domain Tweety PF04906.13 KII83334.1 - 0.057 12.1 0.7 0.082 11.6 0.7 1.1 1 0 0 1 1 1 0 Tweety DUF4229 PF14012.6 KII83334.1 - 2.9 8.1 7.9 0.23 11.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Acetyltransf_1 PF00583.25 KII83338.1 - 7.9e-11 42.2 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII83338.1 - 9.1e-11 42.0 0.1 2.7e-10 40.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII83338.1 - 3.9e-10 39.7 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII83338.1 - 0.027 14.5 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF5052 PF16475.5 KII83340.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) ATG16 PF08614.11 KII83341.1 - 0.0024 18.1 19.9 0.0024 18.1 19.9 3.2 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) SlyX PF04102.12 KII83341.1 - 0.021 15.4 3.8 0.021 15.4 3.8 5.6 4 2 2 6 6 6 0 SlyX DUF5082 PF16888.5 KII83341.1 - 1.3 9.3 28.6 2.7 8.3 0.6 4.9 2 2 0 3 3 3 0 Domain of unknown function (DUF5082) DASH_Dad4 PF08650.10 KII83341.1 - 1.7 8.6 6.5 18 5.4 0.1 4.0 3 1 0 3 3 3 0 DASH complex subunit Dad4 FliJ PF02050.16 KII83341.1 - 3.1 8.0 41.4 0.54 10.5 12.3 3.8 1 1 3 4 4 4 0 Flagellar FliJ protein HAP1_N PF04849.13 KII83341.1 - 4.7 6.3 44.3 0.39 9.9 11.6 4.4 1 1 3 4 4 4 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 KII83341.1 - 5.6 7.0 26.6 5.2 7.1 1.3 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KII83341.1 - 7.7 5.3 55.4 0.38 9.6 11.3 3.7 1 1 2 4 4 4 0 Spc7 kinetochore protein AAA_13 PF13166.6 KII83341.1 - 9.1 4.8 41.0 0.33 9.6 15.4 2.4 1 1 0 2 2 2 0 AAA domain Acetyltransf_10 PF13673.7 KII83343.1 - 1.3e-12 47.7 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII83343.1 - 2.5e-11 43.8 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII83343.1 - 9.6e-09 35.5 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII83343.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KII83343.1 - 7.1e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF5596 PF18082.1 KII83343.1 - 0.018 14.9 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) Acetyltransf_CG PF14542.6 KII83343.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MU117 PF15474.6 KII83344.1 - 2.7e-12 47.4 9.5 3.3e-12 47.1 9.5 1.1 1 0 0 1 1 1 1 Meiotically up-regulated gene family MAD PF05557.13 KII83345.1 - 4.8e-05 22.0 21.9 4.8e-05 22.0 21.9 2.2 2 0 0 2 2 2 1 Mitotic checkpoint protein Spc7 PF08317.11 KII83345.1 - 6.4e-05 22.0 35.2 0.0022 17.0 3.4 3.3 2 1 1 3 3 3 3 Spc7 kinetochore protein ATG16 PF08614.11 KII83345.1 - 0.00014 22.2 50.3 0.025 14.8 7.0 3.8 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 KII83345.1 - 0.0017 17.9 33.9 0.22 11.1 17.8 3.4 2 1 1 3 3 3 2 Mechanosensitive ion channel porin domain HrpB7 PF09486.10 KII83345.1 - 0.0028 18.1 37.5 0.011 16.1 5.6 4.5 2 2 2 4 4 4 2 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 KII83345.1 - 0.0035 17.4 20.9 0.26 11.3 1.3 4.0 2 1 3 5 5 5 2 Protein of unknown function (DUF1664) CENP-H PF05837.12 KII83345.1 - 0.01 16.3 2.1 0.01 16.3 2.1 4.8 2 2 2 4 4 4 1 Centromere protein H (CENP-H) DUF4201 PF13870.6 KII83345.1 - 0.018 14.8 1.4 0.018 14.8 1.4 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 KII83345.1 - 0.021 14.9 36.1 0.96 9.5 13.0 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CC2-LZ PF16516.5 KII83345.1 - 0.028 14.8 27.8 0.29 11.5 2.0 5.1 3 2 1 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF749 PF05370.11 KII83345.1 - 0.075 13.1 1.7 4 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF749) BLOC1S3 PF15753.5 KII83345.1 - 0.11 12.7 18.5 0.21 11.7 3.5 3.4 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4559 PF15112.6 KII83345.1 - 0.16 11.6 14.5 0.96 9.1 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) EzrA PF06160.12 KII83345.1 - 0.26 9.4 27.0 0.28 9.3 14.5 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA YkyA PF10368.9 KII83345.1 - 0.35 10.5 31.4 0.025 14.2 14.0 3.4 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein Sec8_exocyst PF04048.14 KII83345.1 - 0.39 10.6 17.6 0.22 11.4 0.6 4.1 2 2 0 4 4 4 0 Sec8 exocyst complex component specific domain DUF745 PF05335.13 KII83345.1 - 0.47 10.1 31.3 0.31 10.8 15.2 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF745) DUF16 PF01519.16 KII83345.1 - 0.61 10.6 22.2 3 8.4 7.7 3.8 3 1 0 3 3 3 0 Protein of unknown function DUF16 DHR10 PF18595.1 KII83345.1 - 1.2 9.2 45.4 0.55 10.3 3.6 5.2 2 2 3 5 5 5 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 KII83345.1 - 1.2 9.1 27.4 0.42 10.6 1.8 3.9 2 1 2 4 4 4 0 Laminin Domain II Fez1 PF06818.15 KII83345.1 - 1.3 9.4 33.7 0.81 10.1 20.2 2.6 2 1 0 2 2 2 0 Fez1 GAS PF13851.6 KII83345.1 - 1.4 8.2 34.7 4.2 6.7 3.2 3.8 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 KII83345.1 - 1.6 8.2 30.5 3.5 7.1 5.0 2.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 KII83345.1 - 1.8 8.8 37.6 0.42 10.9 4.4 4.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.20 KII83345.1 - 1.9 7.8 43.8 3.3 7.0 19.1 4.4 2 1 1 3 3 3 0 Tropomyosin Atg14 PF10186.9 KII83345.1 - 2 7.4 26.5 2.2 7.3 4.1 2.4 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 KII83345.1 - 3.2 8.7 38.0 0.37 11.7 7.4 3.9 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 KII83345.1 - 3.3 7.5 35.5 0.073 12.9 7.2 2.9 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF5631 PF18645.1 KII83345.1 - 3.3 8.1 7.3 2.6 8.5 0.2 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5631) Filament PF00038.21 KII83345.1 - 3.4 7.2 35.9 4.9 6.6 8.2 3.5 2 2 1 3 3 3 0 Intermediate filament protein UPF0242 PF06785.11 KII83345.1 - 3.8 7.6 30.7 2.4 8.2 4.0 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus YscO PF07321.12 KII83345.1 - 4.3 7.3 38.3 2 8.4 5.5 3.7 2 1 1 3 3 3 0 Type III secretion protein YscO DUF4407 PF14362.6 KII83345.1 - 5 6.4 31.7 0.8 9.0 3.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 KII83345.1 - 5.3 6.8 30.8 2.8 7.7 5.7 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF724) Rab5-bind PF09311.11 KII83345.1 - 6.7 6.0 33.4 2.8 7.3 7.9 3.1 2 1 1 3 3 3 0 Rabaptin-like protein DUF3450 PF11932.8 KII83345.1 - 7 5.9 34.8 0.036 13.4 5.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) HOOK PF05622.12 KII83345.1 - 7.5 4.6 32.7 2.5 6.1 3.4 2.8 2 1 0 2 2 2 0 HOOK protein Jnk-SapK_ap_N PF09744.9 KII83345.1 - 9.2 6.5 40.9 0.65 10.2 1.0 4.5 2 2 2 4 4 4 0 JNK_SAPK-associated protein-1 zf-C2H2 PF00096.26 KII83346.1 - 8.5e-07 29.1 4.6 0.0032 17.9 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII83346.1 - 0.0015 19.2 6.9 0.41 11.6 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII83346.1 - 0.043 13.8 4.2 0.12 12.4 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-MYST PF17772.1 KII83346.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KII83346.1 - 0.086 13.3 3.7 1.2 9.7 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain KASH_CCD PF14662.6 KII83347.1 - 0.006 16.4 0.9 0.015 15.2 0.9 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Cep57_CLD_2 PF14197.6 KII83347.1 - 0.0096 16.0 8.3 0.0096 16.0 8.3 2.3 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 YabA PF06156.13 KII83347.1 - 0.22 12.2 1.6 1.3 9.7 1.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KII83347.1 - 0.31 10.8 3.8 0.19 11.5 0.9 2.1 2 0 0 2 2 2 0 Septum formation initiator Filament PF00038.21 KII83347.1 - 0.83 9.2 15.0 0.19 11.2 9.5 2.3 2 1 0 2 2 2 0 Intermediate filament protein ZapB PF06005.12 KII83347.1 - 4.1 7.9 15.1 0.49 10.9 3.8 3.5 3 0 0 3 3 3 0 Cell division protein ZapB SIKE PF05769.11 KII83348.1 - 0.0057 16.6 0.7 0.01 15.8 0.7 1.4 1 0 0 1 1 1 1 SIKE family EIF4E-T PF10477.9 KII83349.1 - 0.27 10.0 9.2 0.38 9.5 9.2 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SMC_N PF02463.19 KII83350.1 - 3.2e-26 92.1 0.0 7.4e-26 90.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII83350.1 - 2.4e-13 51.1 15.5 2.4e-13 51.1 15.5 4.6 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 KII83350.1 - 9.7e-11 42.0 0.0 3.7e-09 36.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KII83350.1 - 3.5e-06 27.1 1.4 0.0018 18.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII83350.1 - 0.00061 19.5 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PLATZ PF04640.14 KII83350.1 - 0.058 14.0 0.3 0.58 10.8 0.1 2.8 2 0 0 2 2 2 0 PLATZ transcription factor HSBP1 PF06825.12 KII83350.1 - 0.59 10.0 8.7 8.4 6.3 0.1 4.6 4 1 1 5 5 5 0 Heat shock factor binding protein 1 ABC_tran PF00005.27 KII83350.1 - 0.6 10.6 15.4 0.18 12.3 0.3 4.5 3 2 0 4 4 4 0 ABC transporter AAA_13 PF13166.6 KII83350.1 - 0.73 8.4 54.7 0.47 9.0 10.5 4.5 3 1 1 4 4 4 0 AAA domain Fez1 PF06818.15 KII83350.1 - 3.5 8.0 77.1 0.36 11.2 10.1 5.1 2 2 3 5 5 5 0 Fez1 APG6_N PF17675.1 KII83352.1 - 0.011 16.3 10.1 0.011 16.3 10.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 KII83352.1 - 7.2 5.8 18.9 0.38 10.0 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 KII83353.1 - 0.0038 17.8 4.8 0.0038 17.8 4.8 2.0 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Kelch_4 PF13418.6 KII83353.1 - 0.068 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain DUF3450 PF11932.8 KII83353.1 - 0.18 11.1 6.2 0.4 10.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 KII83353.1 - 1.6 9.3 12.6 0.11 13.0 7.4 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region APG6_N PF17675.1 KII83356.1 - 0.025 15.1 10.1 0.025 15.1 10.1 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 KII83356.1 - 1.7 8.4 12.3 0.096 12.5 6.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ERM PF00769.19 KII83356.1 - 6.6 6.5 25.1 0.31 10.8 18.3 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 KII83356.1 - 7 5.9 10.3 14 5.0 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IU_nuc_hydro PF01156.19 KII83357.1 - 3.4e-14 53.1 0.0 5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase IU_nuc_hydro PF01156.19 KII83358.1 - 5.3e-16 59.1 0.0 7.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATG16 PF08614.11 KII83359.1 - 0.007 16.6 8.9 0.007 16.6 8.9 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KII83359.1 - 0.015 15.0 6.7 0.015 15.0 6.7 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mer2 PF09074.10 KII83359.1 - 0.05 13.4 6.3 0.088 12.6 6.3 1.3 1 1 0 1 1 1 0 Mer2 Golgin_A5 PF09787.9 KII83359.1 - 0.51 9.7 24.8 2.1 7.8 12.6 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 bZIP_1 PF00170.21 KII83359.1 - 1 9.5 17.7 0.35 11.0 1.6 3.8 2 1 1 3 3 3 0 bZIP transcription factor Exonuc_VII_L PF02601.15 KII83359.1 - 1.1 8.7 6.2 1.5 8.3 6.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 KII83359.1 - 1.4 9.5 18.3 0.13 12.9 8.4 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 KII83359.1 - 2 9.1 16.7 4.8 7.9 0.7 3.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 KII83359.1 - 4.1 7.5 5.1 16 5.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KII83359.1 - 4.5 7.3 31.7 1.6 8.8 16.4 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 KII83359.1 - 6.8 6.6 7.7 11 6.0 1.5 2.8 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 KII83359.1 - 9.1 6.6 16.5 5.2 7.4 0.5 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper IMPDH PF00478.25 KII83361.1 - 4.1e-128 427.2 5.6 5.8e-128 426.7 5.6 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KII83361.1 - 4.7e-14 52.6 0.7 7.6e-07 29.5 0.0 3.1 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 KII83361.1 - 2e-09 36.9 0.7 5.7e-09 35.5 0.6 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KII83361.1 - 4.3e-05 23.1 3.7 0.0005 19.6 0.6 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KII83361.1 - 5.1e-05 22.8 7.4 0.00094 18.7 4.8 2.4 2 1 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 KII83361.1 - 0.0016 17.8 0.6 0.0033 16.8 0.6 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 KII83361.1 - 0.16 11.0 1.1 2.6 7.0 0.1 2.2 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 KII83361.1 - 0.28 10.6 1.5 1.6 8.1 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Homeodomain PF00046.29 KII83362.1 - 1.2e-16 60.3 0.5 1.8e-16 59.7 0.5 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII83362.1 - 1.3e-05 25.0 0.5 3.2e-05 23.7 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF1942 PF09167.11 KII83364.1 - 0.2 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) LGT PF01790.18 KII83366.1 - 0.042 13.1 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Glyco_hydro_85 PF03644.13 KII83369.1 - 2e-84 283.6 0.0 2.6e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 RRM_1 PF00076.22 KII83371.1 - 1.5e-31 108.0 0.4 4.1e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII83371.1 - 1.4e-11 44.4 0.2 1.6e-05 25.0 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KII83371.1 - 0.0012 18.8 0.2 1.1 9.3 0.0 2.8 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 KII83371.1 - 0.0072 16.2 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 1 RL domain RRM_3 PF08777.11 KII83371.1 - 0.012 15.7 0.0 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF4651 PF15513.6 KII83371.1 - 0.039 13.8 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) EF-hand_12 PF17901.1 KII83371.1 - 0.04 14.4 0.0 0.093 13.2 0.0 1.6 2 0 0 2 2 2 0 EF-hand fold domain Nop14 PF04147.12 KII83373.1 - 0.0098 14.2 2.9 0.013 13.8 2.9 1.2 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 KII83373.1 - 0.012 15.8 1.5 0.022 14.9 1.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KII83373.1 - 0.11 10.8 2.9 0.14 10.4 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein p31comet PF06581.12 KII83373.1 - 0.52 9.4 0.0 0.52 9.4 0.0 2.0 2 1 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding SPX PF03105.19 KII83373.1 - 1.7 8.5 11.5 3.2 7.6 11.5 1.4 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KII83373.1 - 2.2 7.0 5.6 2.9 6.6 5.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SDA1 PF05285.12 KII83373.1 - 2.9 7.2 11.1 0.068 12.6 4.7 1.5 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.13 KII83374.1 - 0.065 13.2 15.6 0.11 12.5 15.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KII83374.1 - 0.47 10.1 27.6 0.7 9.6 2.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KII83374.1 - 0.98 7.6 24.1 1.6 6.8 24.1 1.3 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 KII83374.1 - 1.8 8.4 13.4 3.5 7.4 13.4 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNA_pol_Rpc4 PF05132.14 KII83374.1 - 5.9 7.3 11.0 2.7 8.4 0.7 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Peptidase_S10 PF00450.22 KII83375.1 - 1e-76 259.1 0.5 2.8e-76 257.6 0.5 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase His_binding PF02098.16 KII83375.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Tick histamine binding protein SNO PF01174.19 KII83376.1 - 9.5e-50 169.1 0.0 2e-48 164.7 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KII83376.1 - 9.5e-07 28.6 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KII83376.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Suf PF05843.14 KII83377.1 - 1.5e-72 245.1 3.1 2.2e-70 238.0 0.0 4.3 3 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KII83377.1 - 1.5e-06 28.5 3.4 0.7 10.9 0.0 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII83377.1 - 0.00037 20.9 1.3 0.84 10.2 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII83377.1 - 0.00039 20.9 1.8 0.22 12.2 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA PF00004.29 KII83379.1 - 4.7e-47 159.7 0.0 4e-41 140.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII83379.1 - 2.3e-09 36.9 0.0 7e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KII83379.1 - 3e-06 27.7 0.0 7.1e-05 23.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KII83379.1 - 5.8e-06 26.1 0.0 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KII83379.1 - 2.9e-05 24.3 0.0 6.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KII83379.1 - 0.00057 19.5 0.0 0.51 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KII83379.1 - 0.00079 19.4 0.0 0.0049 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII83379.1 - 0.0025 18.1 2.2 0.18 12.1 0.0 4.1 4 1 0 5 5 4 1 AAA domain AAA_33 PF13671.6 KII83379.1 - 0.0098 16.1 0.4 0.035 14.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KII83379.1 - 0.017 15.7 0.0 0.058 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KII83379.1 - 0.041 14.0 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 KII83379.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KII83379.1 - 0.063 12.7 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KII83379.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KII83379.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KII83379.1 - 0.089 12.5 0.0 1.4 8.6 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KII83379.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KII83379.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 KII83379.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Bromodomain PF00439.25 KII83379.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain Parvo_NS1 PF01057.17 KII83379.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3394 PF11874.8 KII83379.1 - 0.21 11.2 0.0 0.46 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) DAO PF01266.24 KII83380.1 - 6.5e-37 127.9 2.6 7.7e-37 127.7 2.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII83380.1 - 9.1e-05 22.6 0.1 0.00022 21.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII83380.1 - 0.00028 20.2 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KII83380.1 - 0.0033 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII83380.1 - 0.0068 15.5 0.1 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KII83380.1 - 0.0071 16.3 0.1 0.028 14.4 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 KII83380.1 - 0.021 13.6 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 MCRA family FAD_oxidored PF12831.7 KII83380.1 - 0.05 13.0 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KII83380.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pkinase PF00069.25 KII83381.1 - 1.4e-07 31.1 0.0 3.5e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII83381.1 - 1.9e-06 28.0 0.1 0.0005 20.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII83381.1 - 0.0047 16.3 0.1 0.014 14.7 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII83381.1 - 0.011 15.2 0.0 0.13 11.6 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII83382.1 - 0.00012 21.5 0.0 0.0003 20.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII83382.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KII83382.1 - 0.0072 15.6 0.1 0.15 11.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII83382.1 - 0.023 14.7 0.1 3.3 7.6 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII83383.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_1 PF07690.16 KII83384.1 - 3e-38 131.7 47.1 5.3e-38 130.8 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII83384.1 - 5.5e-07 28.4 0.4 5.5e-07 28.4 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex2_Pex12 PF04757.14 KII83384.1 - 0.28 10.7 1.1 0.45 10.1 0.3 1.6 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region AAA PF00004.29 KII83387.1 - 3.3e-93 309.0 0.0 3.5e-47 160.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII83387.1 - 6.5e-23 80.3 1.6 1.3e-10 40.9 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KII83387.1 - 1.1e-14 54.4 0.0 3.2e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KII83387.1 - 1.4e-12 48.3 1.2 0.0018 18.7 0.2 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KII83387.1 - 2.9e-12 47.0 0.5 0.025 14.8 0.0 5.1 2 2 2 5 5 5 2 AAA domain AAA_33 PF13671.6 KII83387.1 - 3.1e-10 40.4 0.0 9.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KII83387.1 - 3.3e-10 40.1 0.7 0.0014 18.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KII83387.1 - 6.7e-10 39.3 0.0 0.001 19.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KII83387.1 - 1.1e-08 34.7 0.0 0.00021 20.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 KII83387.1 - 7.1e-08 32.8 0.0 0.021 15.2 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KII83387.1 - 2.3e-07 30.9 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KII83387.1 - 3.4e-07 29.9 0.4 0.024 14.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KII83387.1 - 4.3e-07 29.8 0.0 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KII83387.1 - 1.4e-06 28.6 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KII83387.1 - 6.7e-06 26.0 0.0 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KII83387.1 - 7.8e-06 26.4 0.0 0.18 12.3 0.0 2.8 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 KII83387.1 - 1.2e-05 25.3 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KII83387.1 - 2e-05 24.1 0.0 0.39 10.0 0.0 3.2 3 0 0 3 3 3 2 KaiC NACHT PF05729.12 KII83387.1 - 2.6e-05 24.2 0.5 0.44 10.4 0.0 3.4 3 1 1 4 4 3 2 NACHT domain Cytidylate_kin2 PF13189.6 KII83387.1 - 3.4e-05 24.1 0.0 0.021 15.0 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Rad17 PF03215.15 KII83387.1 - 5.8e-05 23.1 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain Sigma54_activat PF00158.26 KII83387.1 - 6.1e-05 22.8 0.0 0.44 10.2 0.0 3.6 5 0 0 5 5 4 2 Sigma-54 interaction domain AAA_18 PF13238.6 KII83387.1 - 6.2e-05 23.5 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KII83387.1 - 6.5e-05 22.6 0.9 1.7 8.2 0.1 4.0 3 1 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 KII83387.1 - 9.7e-05 21.7 0.2 0.61 9.3 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_17 PF13207.6 KII83387.1 - 0.00011 22.6 0.0 0.17 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII83387.1 - 0.00015 21.3 0.0 0.78 9.2 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KII83387.1 - 0.00026 20.2 0.0 0.011 14.9 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KII83387.1 - 0.00066 19.8 0.0 2.4 8.3 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 KII83387.1 - 0.00084 19.1 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KII83387.1 - 0.0012 18.1 0.0 0.87 8.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PhoH PF02562.16 KII83387.1 - 0.0013 18.3 0.2 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 KII83387.1 - 0.0014 18.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KII83387.1 - 0.0018 18.0 0.0 0.98 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 KII83387.1 - 0.0024 18.0 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Parvo_NS1 PF01057.17 KII83387.1 - 0.0047 16.1 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 KII83387.1 - 0.0047 16.9 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 KII83387.1 - 0.0056 16.6 0.0 2.1 8.2 0.0 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KII83387.1 - 0.03 13.2 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 KII83387.1 - 0.036 13.3 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.10 KII83387.1 - 0.048 13.1 0.0 10 5.5 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 KII83387.1 - 0.079 12.9 0.0 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KII83387.1 - 0.083 12.6 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KII83387.1 - 0.091 13.1 1.0 22 5.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 KII83387.1 - 0.12 12.6 2.4 4.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Bac_DnaA PF00308.18 KII83387.1 - 0.12 12.1 0.0 5.1 6.9 0.0 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.16 KII83387.1 - 0.22 10.9 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase LRR_4 PF12799.7 KII83388.1 - 0.16 12.4 0.6 2.2 8.8 0.1 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Zn_clus PF00172.18 KII83390.1 - 0.48 10.6 12.1 0.94 9.7 12.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1 PF00415.18 KII83393.1 - 5.1e-42 142.3 15.4 3.5e-14 53.1 0.3 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII83393.1 - 3.1e-16 58.7 30.1 9.4e-07 28.5 1.6 6.2 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KII83393.1 - 1.1e-11 44.5 5.4 1.1e-11 44.5 5.4 2.5 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 KII83393.1 - 0.0048 16.8 0.3 0.018 14.9 0.3 2.0 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.7 KII83393.1 - 0.026 14.8 4.0 0.026 14.8 4.0 2.5 3 0 0 3 3 3 0 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KII83393.1 - 0.75 9.8 9.9 0.07 13.1 4.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KII83393.1 - 1.3 8.7 6.2 1.7 8.2 0.6 3.0 3 0 0 3 3 3 0 PHD-finger DZR PF12773.7 KII83393.1 - 2.3 8.3 11.1 6.7 6.8 7.0 2.9 2 1 0 2 2 2 0 Double zinc ribbon ATG7_N PF16420.5 KII83394.1 - 4.1e-92 309.0 0.0 5.2e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KII83394.1 - 2.9e-47 161.1 0.0 6.4e-47 160.0 0.0 1.5 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.20 KII83394.1 - 0.072 13.2 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 KII83394.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 KII83394.1 - 0.18 11.1 0.0 1 8.7 0.0 2.2 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 KII83397.1 - 1.6e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII83397.1 - 5e-05 23.3 0.1 0.0058 16.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KII83397.1 - 0.00083 18.8 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KII83397.1 - 0.0013 18.0 0.0 0.0045 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Cyt_c_ox_IV PF12270.8 KII83399.1 - 3 8.0 5.8 2.8 8.1 1.3 2.3 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV F-box-like PF12937.7 KII83402.1 - 0.012 15.4 0.5 0.033 14.1 0.5 1.7 1 0 0 1 1 1 0 F-box-like DUF4040 PF13244.6 KII83403.1 - 0.081 13.1 0.5 0.21 11.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) F-box-like PF12937.7 KII83403.1 - 0.14 12.1 0.6 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 F-box-like DUF948 PF06103.11 KII83405.1 - 0.041 14.1 0.1 0.064 13.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SIP PF04954.13 KII83407.1 - 0.04 14.4 2.1 0.054 14.0 2.1 1.3 1 1 0 1 1 1 0 Siderophore-interacting protein DUF389 PF04087.14 KII83407.1 - 2.2 8.3 8.3 2.6 8.1 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF389) Abhydrolase_6 PF12697.7 KII83408.1 - 5.3e-17 63.1 1.9 5.3e-17 63.1 1.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII83408.1 - 1.2e-14 54.5 0.0 5.8e-13 49.1 0.0 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Phasin_2 PF09361.10 KII83408.1 - 0.0067 16.7 8.6 0.0067 16.7 8.6 3.9 1 1 2 3 3 3 3 Phasin protein F-box-like PF12937.7 KII83409.1 - 0.024 14.5 0.4 0.024 14.5 0.4 2.0 2 0 0 2 2 2 0 F-box-like Cupin_2 PF07883.11 KII83409.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin domain F-box-like PF12937.7 KII83410.1 - 7.2e-07 29.0 0.4 1.4e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII83411.1 - 0.016 15.1 0.6 0.016 15.1 0.6 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII83412.1 - 5.7e-08 32.5 0.3 1.3e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII83412.1 - 4 7.4 6.0 19 5.3 2.7 3.2 2 1 0 2 2 2 0 F-box domain DUF4763 PF15960.5 KII83412.1 - 4.9 6.4 6.4 2.2 7.5 4.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) F-box-like PF12937.7 KII83414.1 - 0.028 14.3 1.6 0.061 13.2 0.5 2.1 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII83415.1 - 0.067 13.1 1.7 0.17 11.8 1.7 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KII83416.1 - 0.083 12.8 1.0 0.18 11.7 1.0 1.6 1 0 0 1 1 1 0 F-box-like RFC1 PF08519.12 KII83418.1 - 1.6e-57 194.0 0.0 8e-56 188.5 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KII83418.1 - 5e-14 52.4 0.0 1.7e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KII83418.1 - 1.6e-08 35.1 0.0 4.5e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KII83418.1 - 2.3e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain NTPase_1 PF03266.15 KII83418.1 - 0.018 14.9 0.2 0.12 12.2 0.2 2.1 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 KII83418.1 - 0.027 14.7 0.0 0.092 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KII83418.1 - 0.031 14.0 1.7 0.07 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 KII83418.1 - 0.041 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 KII83418.1 - 0.059 13.5 0.0 0.23 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KII83418.1 - 0.073 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KII83418.1 - 0.077 13.5 1.0 0.27 11.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 KII83418.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KII83418.1 - 0.22 11.9 1.0 0.37 11.2 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain Not1 PF04054.15 KII83419.1 - 0.1 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 KDZ PF18758.1 KII83424.1 - 3.2e-53 180.6 0.3 5.3e-53 179.9 0.3 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83424.1 - 3.4e-42 143.0 0.7 6.2e-42 142.1 0.7 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII83424.1 - 0.1 12.7 0.7 0.26 11.5 0.4 1.8 1 1 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KII83427.1 - 5.1e-07 29.9 0.6 3.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin DinB_2 PF12867.7 KII83428.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.1 1 1 0 2 2 2 0 DinB superfamily Fez1 PF06818.15 KII83429.1 - 0.06 13.8 13.0 0.19 12.1 12.8 1.8 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KII83429.1 - 0.14 12.1 7.2 0.42 10.6 7.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 KII83429.1 - 0.21 10.6 11.7 0.3 10.1 11.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 KII83429.1 - 0.24 11.7 1.4 2.3 8.5 0.1 3.2 4 0 0 4 4 3 0 Homeobox associated leucine zipper SOGA PF11365.8 KII83429.1 - 0.25 12.5 4.6 0.15 13.2 1.5 2.0 2 0 0 2 2 2 0 Protein SOGA EURL PF06937.11 KII83429.1 - 0.3 10.5 3.6 0.52 9.7 3.6 1.3 1 0 0 1 1 1 0 EURL protein MscS_porin PF12795.7 KII83429.1 - 0.51 9.8 31.7 1.7 8.1 31.7 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KII83429.1 - 0.54 10.5 23.1 1.2 9.4 22.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 KII83429.1 - 1.5 7.3 7.3 0.32 9.6 2.8 1.7 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.13 KII83429.1 - 2.2 7.8 8.4 4.2 6.9 3.3 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF4763 PF15960.5 KII83429.1 - 2.8 7.2 9.0 0.66 9.2 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) TMF_DNA_bd PF12329.8 KII83429.1 - 5 7.2 6.6 0.98 9.5 1.4 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding JIP_LZII PF16471.5 KII83429.1 - 5.2 7.3 6.5 17 5.6 0.5 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Herpes_ORF11 PF04797.13 KII83431.1 - 0.01 14.7 0.0 0.038 12.8 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus dUTPase protein gag-asp_proteas PF13975.6 KII83431.1 - 0.035 14.7 0.0 0.11 13.1 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Prot_ATP_ID_OB PF16450.5 KII83433.1 - 0.099 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Chromo PF00385.24 KII83434.1 - 6.1e-11 42.1 0.0 6.7e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VWA_2 PF13519.6 KII83436.1 - 0.15 12.7 0.0 0.15 12.7 0.0 1.0 1 0 0 1 1 1 0 von Willebrand factor type A domain HipA_C PF07804.12 KII83437.1 - 0.072 12.8 0.0 0.075 12.7 0.0 1.0 1 0 0 1 1 1 0 HipA-like C-terminal domain Dimer_Tnp_hAT PF05699.14 KII83438.1 - 9.8e-07 28.5 0.0 1.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region Plavaka PF18759.1 KII83440.1 - 5e-25 88.4 0.0 8.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase BUD22 PF09073.10 KII83443.1 - 1.4 8.2 11.4 1.5 8.0 11.4 1.0 1 0 0 1 1 1 0 BUD22 RhoGAP PF00620.27 KII83448.1 - 0.0011 18.8 0.0 0.0042 16.9 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain KDZ PF18758.1 KII83451.1 - 1.8e-58 197.8 0.0 2.3e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII83451.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases DUF4510 PF14971.6 KII83452.1 - 0.0078 16.6 0.1 0.054 13.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4510) Plavaka PF18759.1 KII83453.1 - 3e-23 82.6 0.0 3.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KII83454.1 - 7.4e-20 71.4 1.8 1.3e-19 70.7 1.8 1.4 1 0 0 1 1 1 1 Plavaka transposase Dimer_Tnp_hAT PF05699.14 KII83456.1 - 0.00076 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Roughex PF06020.11 KII83456.1 - 1.4 8.0 9.1 1.7 7.7 9.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein KDZ PF18758.1 KII83460.1 - 3.8e-60 203.3 0.0 6e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83460.1 - 8.1e-07 29.2 0.1 1.7e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII83460.1 - 3.3e-05 24.0 0.1 7.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases GAS PF13851.6 KII83461.1 - 0.013 14.8 0.7 0.015 14.6 0.7 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF5555 PF17710.1 KII83461.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5555) DUF4186 PF13811.6 KII83461.1 - 0.13 12.3 0.3 0.19 11.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) Apis_Csd PF11671.8 KII83461.1 - 0.14 12.2 4.1 0.18 11.8 4.1 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein 2OG-FeII_Oxy_3 PF13640.6 KII83463.1 - 0.023 15.6 0.0 0.034 15.0 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ALGX PF16822.5 KII83464.1 - 0.34 10.5 3.1 0.64 9.6 3.1 1.3 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Pkinase PF00069.25 KII83466.1 - 2.1e-06 27.3 0.0 3.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83466.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KII83467.1 - 5.5e-32 111.2 0.0 9.1e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83467.1 - 3.1e-05 23.4 0.0 5.9e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII83467.1 - 0.028 13.8 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII83467.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KII83467.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribonuc_red_sm PF00268.21 KII83468.1 - 9.1e-62 209.0 0.0 1e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.6 KII83475.1 - 6.3e-13 48.9 0.0 9.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII83475.1 - 9.2e-11 42.3 0.0 1.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII83475.1 - 2.5e-09 37.1 0.0 1.7e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII83475.1 - 3.6e-07 30.8 0.0 6.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KII83475.1 - 4.1e-06 26.3 0.0 6.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KII83475.1 - 3.1e-05 24.6 0.0 0.00011 22.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII83475.1 - 0.0023 17.3 0.0 0.034 13.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KII83475.1 - 0.0051 16.7 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KII83475.1 - 0.0088 14.6 0.0 0.097 11.2 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KII83475.1 - 0.011 15.2 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KII83475.1 - 0.013 15.0 0.0 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KII83475.1 - 0.016 14.5 0.0 0.066 12.5 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KII83475.1 - 0.062 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF1388 PF07142.12 KII83483.1 - 9.6 6.3 11.0 4.9 7.2 0.1 3.4 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) DUF4707 PF15806.5 KII83490.1 - 1.1 8.1 4.7 0.17 10.8 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4707) UPF0242 PF06785.11 KII83491.1 - 3.1e-05 24.2 3.4 3.1e-05 24.2 3.4 2.4 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Rab5-bind PF09311.11 KII83491.1 - 0.003 17.0 5.1 0.003 17.0 5.1 2.9 2 1 1 3 3 3 1 Rabaptin-like protein HMMR_C PF15908.5 KII83491.1 - 0.01 16.1 7.5 0.16 12.2 0.3 3.1 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal WXG100 PF06013.12 KII83491.1 - 0.24 11.7 15.1 0.12 12.7 8.0 3.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG YabA PF06156.13 KII83491.1 - 0.37 11.5 9.4 0.34 11.6 1.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KII83491.1 - 0.48 10.4 17.1 0.76 9.8 8.2 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.9 KII83491.1 - 0.56 9.5 14.3 0.32 10.3 10.7 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HALZ PF02183.18 KII83491.1 - 1.3 9.3 13.2 0.76 10.0 0.3 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper DUF1515 PF07439.11 KII83491.1 - 1.7 8.7 14.6 0.96 9.5 2.5 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) Rootletin PF15035.6 KII83491.1 - 2.5 8.1 26.2 0.02 14.9 4.4 3.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.19 KII83491.1 - 8.9 4.1 6.2 17 3.2 2.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mto2_bdg PF12808.7 KII83493.1 - 0.022 15.1 5.0 0.053 13.8 5.0 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mac PF12464.8 KII83493.1 - 1.3 9.4 7.0 3.5 7.9 1.9 3.1 2 1 0 2 2 2 0 Maltose acetyltransferase KDZ PF18758.1 KII83494.1 - 0.00032 20.4 1.0 0.00032 20.4 1.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 KII83495.1 - 1.1e-43 148.3 0.2 2.5e-43 147.1 0.2 1.7 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases MSA-2c PF12238.8 KII83496.1 - 0.28 11.2 3.9 0.46 10.5 3.9 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c UPF0242 PF06785.11 KII83505.1 - 5.4e-05 23.4 3.4 5.4e-05 23.4 3.4 2.3 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus Rab5-bind PF09311.11 KII83505.1 - 0.0069 15.8 4.8 0.0069 15.8 4.8 2.9 2 1 1 3 3 3 1 Rabaptin-like protein HMMR_C PF15908.5 KII83505.1 - 0.28 11.4 8.1 0.92 9.8 0.2 3.1 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal CENP-F_leu_zip PF10473.9 KII83505.1 - 0.4 10.7 14.0 1.1 9.2 7.1 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KII83505.1 - 0.55 10.9 8.7 0.37 11.5 0.5 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Rootletin PF15035.6 KII83505.1 - 1 9.3 22.3 0.034 14.2 4.6 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF1515 PF07439.11 KII83505.1 - 2.2 8.3 12.9 0.42 10.7 1.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) Fez1 PF06818.15 KII83505.1 - 2.4 8.5 17.5 1.6 9.1 10.9 2.6 2 1 0 2 2 2 0 Fez1 HALZ PF02183.18 KII83505.1 - 2.7 8.3 10.5 2.7 8.3 2.2 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper Macoilin PF09726.9 KII83508.1 - 0.0022 16.7 2.7 0.0026 16.4 2.7 1.1 1 0 0 1 1 1 1 Macoilin family UPF0242 PF06785.11 KII83508.1 - 0.011 15.9 1.5 0.019 15.1 1.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rab5-bind PF09311.11 KII83508.1 - 0.013 14.9 4.8 0.013 14.9 4.8 2.2 1 1 1 2 2 2 0 Rabaptin-like protein GAS PF13851.6 KII83508.1 - 0.034 13.5 12.2 0.24 10.7 2.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KII83508.1 - 0.13 10.4 7.7 0.18 9.9 7.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KII83508.1 - 0.47 9.3 14.7 0.13 11.1 11.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 KII83508.1 - 1.7 8.6 3.7 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF724 PF05266.14 KII83508.1 - 2.5 7.9 4.4 59 3.4 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 KII83508.1 - 4.5 7.7 17.4 0.27 11.7 5.7 2.2 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 KII83508.1 - 8.3 7.1 5.5 8.8 7.0 1.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Peptidase_C48 PF02902.19 KII83509.1 - 0.00022 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MrpF_PhaF PF04066.13 KII83509.1 - 0.14 12.6 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DEAD PF00270.29 KII83513.1 - 1.4e-12 47.7 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII83513.1 - 4.8e-11 43.0 0.0 1.5e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII83513.1 - 1.3e-06 28.5 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RVT_1 PF00078.27 KII83516.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KII83516.1 - 0.007 17.1 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase WW_1 PF18507.1 KII83518.1 - 0.1 12.3 0.6 0.25 11.1 0.6 1.6 1 0 0 1 1 1 0 WW domain Cyclin PF08613.11 KII83520.1 - 0.0016 18.8 0.3 0.0025 18.2 0.3 1.6 1 1 0 1 1 1 1 Cyclin Cupin_5 PF06172.11 KII83521.1 - 0.051 13.7 0.1 0.29 11.3 0.0 2.0 1 1 1 2 2 2 0 Cupin superfamily (DUF985) RCC1 PF00415.18 KII83524.1 - 2.1e-39 133.9 9.3 8.9e-10 39.0 0.0 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII83524.1 - 8e-26 89.2 20.6 1.7e-07 30.9 0.7 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KII83525.1 - 0.014 15.2 0.1 0.068 13.1 0.0 2.1 3 0 0 3 3 3 0 F-box-like Rubi_NSP_C PF12601.8 KII83527.1 - 0.023 14.8 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 Rubivirus non-structural protein CCDC24 PF15669.5 KII83527.1 - 0.54 10.1 4.7 1.5 8.7 4.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family PARM PF17061.5 KII83527.1 - 6.7 6.8 17.9 0.71 10.0 12.6 1.9 2 0 0 2 2 2 0 PARM Ndc1_Nup PF09531.10 KII83527.1 - 8.3 5.0 6.9 12 4.4 6.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spore_YpjB PF09577.10 KII83530.1 - 0.0034 17.2 1.8 0.0071 16.2 1.8 1.6 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) DDE_1 PF03184.19 KII83531.1 - 3.5e-19 69.1 0.0 7.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KII83531.1 - 1.4e-05 25.0 1.0 1.4e-05 25.0 1.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KII83531.1 - 0.0038 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease FlxA PF14282.6 KII83531.1 - 0.38 10.8 6.3 0.67 10.0 5.5 1.8 1 1 0 1 1 1 0 FlxA-like protein adh_short PF00106.25 KII83532.1 - 1.8e-23 83.0 0.4 2.5e-23 82.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII83532.1 - 8.3e-19 68.1 1.0 1e-18 67.7 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII83532.1 - 0.00079 19.4 0.1 0.00091 19.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII83532.1 - 0.0017 18.3 1.3 0.0023 17.9 1.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Kinesin PF00225.23 KII83533.1 - 2.8e-75 253.3 0.0 3.2e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII83533.1 - 1.3e-12 47.9 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding GHMP_kinases_C PF08544.13 KII83538.1 - 7.5e-05 23.0 0.0 0.00018 21.8 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases C terminal WXG100 PF06013.12 KII83538.1 - 0.086 13.1 0.6 0.18 12.1 0.3 1.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Fungal_trans PF04082.18 KII83542.1 - 4.9e-16 58.5 0.2 9.1e-16 57.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII83542.1 - 6.9e-06 26.1 11.1 1.2e-05 25.3 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecl1 PF12855.7 KII83543.1 - 0.007 17.6 10.3 0.007 17.6 10.3 5.4 2 1 2 5 5 5 2 ECL1/2/3 zinc binding proteins Csm4_C PF17953.1 KII83544.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Plavaka PF18759.1 KII83546.1 - 1.5e-128 428.6 0.0 1.8e-128 428.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Pinin_SDK_N PF04697.13 KII83548.1 - 0.014 16.0 3.4 2.6 8.7 0.2 2.7 2 0 0 2 2 2 0 pinin/SDK conserved region Glyco_hyd_65N_2 PF14498.6 KII83548.1 - 0.3 10.9 4.1 0.39 10.5 3.7 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sec20 PF03908.13 KII83548.1 - 0.58 10.1 11.9 0.26 11.2 0.5 2.9 3 0 0 3 3 3 0 Sec20 Spc7 PF08317.11 KII83548.1 - 2.9 6.7 26.7 0.17 10.7 10.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.15 KII83548.1 - 9.9 6.3 16.7 6.2 7.0 6.3 2.8 1 1 1 2 2 2 0 RasGAP C-terminus Dcc1 PF09724.9 KII83549.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 zf-MYND PF01753.18 KII83550.1 - 2.1e-06 27.7 10.0 4.5e-06 26.6 10.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII83550.1 - 0.14 12.5 10.2 0.35 11.2 10.2 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Retrotran_gag_2 PF14223.6 KII83559.1 - 3.4e-08 33.2 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII83559.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KII83559.1 - 0.11 12.2 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 KII83560.1 - 7.1e-11 41.9 0.0 9.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII83560.1 - 0.0054 16.7 3.3 0.0099 15.9 3.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KII83560.1 - 2.1 8.2 6.5 3.8 7.4 6.5 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KII83561.1 - 2.9e-15 56.2 0.0 3.1e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AT_hook PF02178.19 KII83567.1 - 1.7 8.8 9.2 0.14 12.1 2.4 2.9 2 0 0 2 2 2 0 AT hook motif HBM PF16591.5 KII83567.1 - 4.8 6.5 8.3 1.4 8.3 0.6 2.3 2 0 0 2 2 2 0 Helical bimodular sensor domain Plavaka PF18759.1 KII83568.1 - 1.2e-127 425.7 0.0 1.6e-127 425.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Deltaretro_Tax PF05599.11 KII83568.1 - 0.015 15.8 0.1 0.047 14.2 0.1 1.9 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Rod_cone_degen PF15201.6 KII83569.1 - 0.093 12.8 1.3 2.6 8.2 0.1 2.9 2 0 0 2 2 2 0 Progressive rod-cone degeneration Helicase_C PF00271.31 KII83572.1 - 1.1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alveol-reg_P311 PF11092.8 KII83572.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) STI1 PF17830.1 KII83575.1 - 0.083 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 STI1 domain gag-asp_proteas PF13975.6 KII83581.1 - 0.081 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Myb_DNA-bind_5 PF13873.6 KII83583.1 - 0.11 12.6 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain KDZ PF18758.1 KII83586.1 - 4.9e-63 212.7 0.0 7.7e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83586.1 - 3.9e-08 33.4 0.1 8.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII83586.1 - 2.8e-05 24.2 0.2 6e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PRIMA1 PF16101.5 KII83589.1 - 0.0023 18.0 6.1 0.0023 18.0 6.1 4.9 4 2 3 7 7 7 1 Proline-rich membrane anchor 1 Asp_protease_2 PF13650.6 KII83591.1 - 0.098 13.3 0.0 0.95 10.2 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease RVP_2 PF08284.11 KII83591.1 - 0.12 12.1 0.0 2.3 8.0 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease NACHT PF05729.12 KII83593.1 - 7.9e-09 35.6 0.0 2.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII83593.1 - 3.8e-07 30.6 0.0 1.4e-06 28.8 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KII83593.1 - 0.007 16.8 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII83593.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KII83593.1 - 0.038 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KII83593.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KII83593.1 - 0.048 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Patatin PF01734.22 KII83594.1 - 2e-13 51.0 0.0 3.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Ish1 PF10281.9 KII83599.1 - 1.4e-53 178.9 29.5 2.8e-11 43.5 1.5 7.7 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KII83599.1 - 5.8e-06 25.9 0.0 1.2 9.0 0.0 5.2 6 0 0 6 6 6 2 SAP domain HeH PF12949.7 KII83599.1 - 0.00041 20.0 2.4 2.2 8.1 0.1 4.3 5 0 0 5 5 5 2 HeH/LEM domain GYF PF02213.16 KII83599.1 - 0.016 14.9 2.2 10 5.9 0.0 3.5 3 0 0 3 3 3 0 GYF domain Anthrax_toxA PF03497.16 KII83599.1 - 0.064 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Anthrax toxin LF subunit Slx4 PF09494.10 KII83599.1 - 0.069 13.1 1.5 18 5.4 0.0 4.0 3 2 0 3 3 3 0 Slx4 endonuclease SLATT_4 PF18186.1 KII83599.1 - 0.071 12.8 3.6 6.8 6.3 0.0 4.0 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 4 Thymopoietin PF08198.11 KII83599.1 - 0.17 11.5 0.1 10 5.8 0.0 3.4 5 0 0 5 5 5 0 Thymopoietin protein SAM_2 PF07647.17 KII83599.1 - 0.37 10.9 12.3 3.1 8.0 0.1 4.9 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) BRK PF07533.16 KII83599.1 - 6.6 6.4 5.7 18 5.0 0.3 3.2 3 0 0 3 3 3 0 BRK domain DUF2443 PF10398.9 KII83601.1 - 0.029 14.4 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) NACHT PF05729.12 KII83602.1 - 1.2e-08 35.1 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII83602.1 - 1.2e-05 25.8 0.0 1.9e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KII83602.1 - 0.00038 19.7 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KII83602.1 - 0.0022 18.4 0.1 0.0027 18.1 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KII83602.1 - 0.0023 17.8 0.0 0.0024 17.8 0.0 1.3 1 1 0 1 1 1 1 NTPase APS_kinase PF01583.20 KII83602.1 - 0.0026 17.6 0.2 0.012 15.6 0.1 1.9 1 1 1 2 2 2 1 Adenylylsulphate kinase ATPase_2 PF01637.18 KII83602.1 - 0.0045 16.9 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KII83602.1 - 0.0088 16.6 0.1 0.0091 16.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KII83602.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII83602.1 - 0.019 15.1 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII83602.1 - 0.024 15.0 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KII83602.1 - 0.045 14.0 0.0 0.075 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KII83602.1 - 0.061 13.3 0.0 0.089 12.8 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 KII83602.1 - 0.072 12.8 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase IstB_IS21 PF01695.17 KII83602.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol3_delta2 PF13177.6 KII83602.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit WD40 PF00400.32 KII83603.1 - 1e-97 317.4 40.9 2.1e-11 44.2 0.3 9.8 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII83603.1 - 9.5e-33 112.4 1.9 0.031 14.6 0.0 9.1 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII83603.1 - 1.9e-20 73.1 14.2 0.083 11.8 0.0 9.0 1 1 8 9 9 9 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KII83603.1 - 1.6e-14 53.4 6.1 6.2 6.9 0.0 9.2 9 0 0 9 9 9 4 WD40-like Beta Propeller Repeat Frtz PF11768.8 KII83603.1 - 1.9e-12 46.3 0.0 0.021 13.1 0.0 6.6 1 1 5 7 7 7 6 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KII83603.1 - 1.3e-10 41.2 0.0 0.032 13.6 0.0 5.8 3 3 4 7 7 7 3 WD40-like domain potato_inhibit PF00280.18 KII83603.1 - 2.8e-07 31.1 0.2 10 6.9 0.0 7.2 3 2 6 9 9 9 1 Potato inhibitor I family DUF374 PF04028.13 KII83603.1 - 8.5e-05 22.0 8.8 6.1 6.5 0.1 6.7 4 2 2 6 6 6 1 Domain of unknown function (DUF374) Nup160 PF11715.8 KII83603.1 - 0.005 15.6 7.0 2.6 6.6 0.1 5.4 1 1 3 6 6 6 1 Nucleoporin Nup120/160 GspH PF12019.8 KII83603.1 - 0.048 14.1 17.7 28 5.2 0.2 6.7 1 1 4 5 5 5 0 Type II transport protein GspH WD40_3 PF15911.5 KII83603.1 - 2.4 8.2 9.0 66 3.6 0.0 6.3 9 0 0 9 9 9 0 WD domain, G-beta repeat NACHT PF05729.12 KII83607.1 - 2.4e-09 37.3 0.0 8.1e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KII83607.1 - 2.8e-09 37.6 0.0 8.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KII83607.1 - 0.0023 18.3 0.1 0.011 16.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII83607.1 - 0.028 14.7 0.0 0.2 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KII83607.1 - 0.034 13.9 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KII83607.1 - 0.059 13.3 0.1 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KII83607.1 - 0.088 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KII83607.1 - 0.16 12.5 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KII83608.1 - 8.2e-136 437.9 56.0 1.9e-10 41.1 0.2 13.3 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII83608.1 - 1.2e-46 157.0 11.6 0.0018 18.6 0.0 12.1 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII83608.1 - 6e-22 78.3 0.1 0.0098 15.2 0.0 9.7 3 2 8 11 11 11 9 WD40-like domain Ge1_WD40 PF16529.5 KII83608.1 - 7.1e-19 67.9 10.4 0.16 10.9 0.0 11.1 1 1 11 12 12 12 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KII83608.1 - 8.9e-16 57.3 0.0 0.47 8.7 0.0 8.6 4 3 5 9 9 9 6 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KII83608.1 - 8.7e-10 38.3 8.1 6.7 6.8 0.0 10.7 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat potato_inhibit PF00280.18 KII83608.1 - 7.3e-09 36.2 0.5 11 6.8 0.0 8.7 4 4 8 12 12 12 2 Potato inhibitor I family Nup160 PF11715.8 KII83608.1 - 3.3e-07 29.3 17.6 4.6 5.8 0.0 10.3 1 1 8 12 12 12 1 Nucleoporin Nup120/160 PQQ PF01011.21 KII83608.1 - 5.7e-07 29.2 0.2 14 5.8 0.0 8.0 8 0 0 8 8 8 0 PQQ enzyme repeat DUF1258 PF06869.12 KII83608.1 - 0.00048 19.7 0.3 7.9 5.9 0.0 5.1 2 2 2 6 6 6 1 Protein of unknown function (DUF1258) FrpC PF06901.12 KII83608.1 - 0.0008 19.1 0.7 12 5.4 0.0 4.6 5 3 0 5 5 5 0 RTX iron-regulated protein FrpC Peptidase_C9 PF01707.16 KII83608.1 - 0.039 13.5 0.2 44 3.6 0.0 5.3 5 2 3 8 8 8 0 Peptidase family C9 SoxZ PF08770.11 KII83608.1 - 0.068 12.9 0.4 15 5.4 0.0 4.3 5 0 0 5 5 5 0 Sulphur oxidation protein SoxZ LydB PF16084.5 KII83608.1 - 0.075 12.8 0.2 98 2.7 0.0 4.5 3 2 2 5 5 5 0 LydA-holin antagonist PepSY PF03413.19 KII83608.1 - 3.3 8.4 6.8 1.1e+02 3.5 0.0 5.4 8 0 0 8 8 7 0 Peptidase propeptide and YPEB domain Retrotran_gag_3 PF14244.6 KII83609.1 - 0.026 14.3 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DEC-1_N PF04625.13 KII83609.1 - 0.03 13.4 3.5 0.03 13.4 3.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retrotran_gag_2 PF14223.6 KII83609.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Trypan_PARP PF05887.11 KII83610.1 - 0.0046 16.9 3.4 0.0046 16.9 3.4 2.3 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) STIL_N PF15253.6 KII83610.1 - 0.18 10.7 4.0 0.26 10.2 4.0 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus p450 PF00067.22 KII83611.1 - 2.9e-68 230.7 0.0 1.2e-67 228.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PPR_2 PF13041.6 KII83612.1 - 3e-05 24.1 0.0 0.4 10.9 0.0 4.0 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KII83612.1 - 0.001 19.1 0.0 2.3 8.4 0.0 4.1 3 1 2 5 5 5 1 Pentatricopeptide repeat domain DUF1106 PF06523.11 KII83613.1 - 0.12 12.4 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Zn_clus PF00172.18 KII83614.1 - 5.8e-10 39.1 6.2 8.3e-10 38.6 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_2 PF13532.6 KII83615.1 - 5.6e-11 43.0 0.0 1e-09 38.9 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily dCMP_cyt_deam_1 PF00383.23 KII83616.1 - 2e-13 50.1 0.0 3.6e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII83616.1 - 0.004 16.9 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 MafB19-like deaminase PEMT PF04191.13 KII83617.1 - 7.2e-51 171.0 15.0 7.3e-29 100.3 2.2 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 KII83617.1 - 0.01 16.3 0.0 0.028 15.0 0.0 1.7 1 1 0 1 1 1 0 SKICH domain HECW_N PF16562.5 KII83617.1 - 0.056 13.3 0.1 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 PID PF00640.23 KII83617.1 - 0.068 13.2 0.0 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) DUF389 PF04087.14 KII83617.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF389) UbiA PF01040.18 KII83620.1 - 3.4e-23 82.3 7.9 4.1e-23 82.0 7.5 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KII83621.1 - 1.7e-69 234.8 0.0 2.1e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF_4G1 PF12152.8 KII83621.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Sacchrp_dh_NADP PF03435.18 KII83622.1 - 9.8e-18 64.7 0.4 1.6e-17 64.0 0.4 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KII83622.1 - 0.00014 22.2 0.1 0.00039 20.8 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KII83622.1 - 0.00021 21.2 0.4 0.00034 20.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KII83622.1 - 0.00028 20.8 0.3 0.00061 19.8 0.3 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KII83622.1 - 0.0013 18.3 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KII83622.1 - 0.028 13.9 0.2 0.055 12.9 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 KII83622.1 - 0.044 13.8 0.2 0.079 13.0 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KII83622.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII83622.1 - 0.13 11.2 0.1 0.25 10.3 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GMC_oxred_N PF00732.19 KII83623.1 - 7.2e-64 216.0 0.0 9.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII83623.1 - 2.2e-36 125.6 0.0 4.3e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII83623.1 - 7.6e-07 28.6 0.1 7.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KII83623.1 - 2.4e-05 24.5 0.1 7.9e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KII83623.1 - 0.00016 20.9 0.5 0.00028 20.1 0.5 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KII83623.1 - 0.00019 20.8 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII83623.1 - 0.00052 19.3 0.1 0.03 13.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII83623.1 - 0.0014 18.3 4.9 0.015 14.9 4.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII83623.1 - 0.073 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family p450 PF00067.22 KII83625.1 - 3e-73 247.1 0.0 3.7e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box_5 PF18511.1 KII83626.1 - 0.065 12.8 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box DUF3267 PF11667.8 KII83626.1 - 0.16 12.2 7.6 0.035 14.4 3.4 2.0 2 1 1 3 3 3 0 Putative zincin peptidase Pan3_PK PF18101.1 KII83627.1 - 1.5e-63 212.9 0.1 2.5e-63 212.1 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KII83627.1 - 2.2e-07 30.5 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83627.1 - 4.1e-05 23.0 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UbiA PF01040.18 KII83628.1 - 4.1e-24 85.3 6.6 5.7e-24 84.8 6.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Lon_C PF05362.13 KII83629.1 - 7.6e-66 221.5 0.5 1.3e-65 220.8 0.5 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KII83629.1 - 3.5e-22 79.2 0.0 8.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KII83629.1 - 9.8e-11 41.8 0.0 5.2e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 KII83629.1 - 1.8e-10 41.0 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KII83629.1 - 1.2e-06 28.3 0.0 4.3e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KII83629.1 - 3e-05 24.2 0.0 0.00011 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KII83629.1 - 0.00015 22.2 0.1 0.001 19.4 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KII83629.1 - 0.0041 16.9 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KII83629.1 - 0.0059 16.5 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII83629.1 - 0.014 15.7 0.5 1.2 9.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KII83629.1 - 0.02 15.4 0.1 0.17 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KII83629.1 - 0.029 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KII83629.1 - 0.077 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 KII83629.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KII83629.1 - 0.094 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KII83629.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII83629.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KII83629.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KII83629.1 - 0.17 11.8 0.1 2.1 8.2 0.0 2.6 2 1 1 3 3 2 0 NTPase AAA_11 PF13086.6 KII83629.1 - 0.24 11.2 1.4 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain GPR_Gpa2_C PF11970.8 KII83630.1 - 0.082 13.0 0.4 0.22 11.6 0.4 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term GMC_oxred_N PF00732.19 KII83632.1 - 1.3e-60 205.3 0.0 1.6e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII83632.1 - 5.6e-39 133.9 0.0 9.2e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII83632.1 - 3.2e-05 23.2 0.1 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KII83632.1 - 0.001 19.3 1.2 0.0019 18.4 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII83632.1 - 0.001 18.7 1.9 0.0044 16.7 1.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII83632.1 - 0.0018 17.6 0.1 0.78 8.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII83632.1 - 0.003 16.7 0.2 0.0047 16.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII83632.1 - 0.0042 16.3 0.9 0.02 14.1 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Gly_rich_SFCGS PF14272.6 KII83632.1 - 0.099 12.7 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Glycine-rich SFCGS Thi4 PF01946.17 KII83632.1 - 0.13 11.5 0.2 0.22 10.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.19 KII83633.1 - 1.8e-59 201.5 0.0 2.4e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII83633.1 - 1.4e-35 122.9 0.0 2.3e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII83633.1 - 0.00018 20.7 0.2 0.00027 20.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII83633.1 - 0.00061 20.0 1.7 0.0019 18.4 1.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII83633.1 - 0.0036 16.6 0.1 0.0075 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII83633.1 - 0.0077 15.9 1.8 0.0077 15.9 1.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII83633.1 - 0.01 15.1 0.1 0.01 15.1 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 KII83633.1 - 0.13 11.3 4.2 0.05 12.7 1.6 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KII83633.1 - 0.18 11.0 0.8 0.3 10.3 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2968 PF11180.8 KII83634.1 - 0.0035 17.0 11.0 0.0035 17.0 11.0 5.8 3 1 3 6 6 6 3 Protein of unknown function (DUF2968) Phage_GP20 PF06810.11 KII83634.1 - 0.25 11.1 40.4 0.47 10.2 4.9 5.5 2 1 3 5 5 5 0 Phage minor structural protein GP20 PatG_C PF18065.1 KII83634.1 - 0.34 10.9 2.4 1.3 9.0 0.5 2.3 1 1 1 2 2 2 0 PatG C-terminal Baculo_PEP_C PF04513.12 KII83634.1 - 5.8 7.0 15.3 3.1 7.8 3.8 3.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 KII83634.1 - 7.9 7.0 103.5 1.2 9.7 19.3 7.2 1 1 5 6 6 6 0 Apg6 coiled-coil region PAP_assoc PF03828.19 KII83640.1 - 7.7e-17 61.3 0.0 1.5e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KII83640.1 - 2.4e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KII83640.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase LSM PF01423.22 KII83642.1 - 4.8e-19 67.8 0.0 5.6e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KII83642.1 - 0.032 14.4 0.2 0.085 13.0 0.2 1.7 1 1 1 2 2 2 0 RimP C-terminal SH3 domain HEAT PF02985.22 KII83643.1 - 2.4e-16 58.4 11.1 0.0003 20.8 0.0 10.2 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 KII83643.1 - 2.4e-15 56.6 14.4 2.5e-10 40.6 0.0 7.9 7 2 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KII83643.1 - 1.4e-12 47.8 1.7 0.007 16.7 0.0 7.9 3 2 4 7 7 7 5 HEAT repeats IBN_N PF03810.19 KII83643.1 - 2.1e-09 37.2 1.2 9.4e-08 31.9 0.1 4.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 KII83643.1 - 6.6e-07 29.2 8.7 0.00086 19.3 0.1 5.4 6 0 0 6 6 4 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KII83643.1 - 1.1e-05 24.2 1.8 0.85 8.1 0.1 3.4 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 KII83643.1 - 1.6e-05 24.6 0.0 4.1 6.9 0.0 4.5 2 1 2 4 4 4 2 CLASP N terminal DUF3385 PF11865.8 KII83643.1 - 0.00012 22.1 0.9 1 9.3 0.1 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KII83643.1 - 0.00015 21.9 2.3 0.0021 18.1 0.1 3.6 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 KII83643.1 - 0.00031 19.2 1.5 0.75 8.0 0.1 4.0 3 1 1 4 4 4 2 Down-regulated in metastasis MMS19_C PF12460.8 KII83643.1 - 0.0017 17.6 1.3 3.1 6.8 0.0 3.4 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 KII83643.1 - 0.11 12.2 0.1 0.67 9.7 0.0 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Amino_oxidase PF01593.24 KII83644.1 - 5e-32 111.8 0.0 8e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII83644.1 - 2.1e-07 31.0 0.0 6.3e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII83644.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII83644.1 - 0.23 10.7 0.1 0.38 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain p450 PF00067.22 KII83645.1 - 1.6e-55 188.7 0.0 2.1e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MPP6 PF10175.9 KII83646.1 - 6.9e-06 26.6 0.0 6.9e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 M-phase phosphoprotein 6 Cullin_binding PF03556.15 KII83650.1 - 9.3e-35 119.7 0.3 1.6e-34 118.9 0.3 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 KII83650.1 - 8.8e-07 28.6 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DHHC PF01529.20 KII83651.1 - 2.7e-36 124.6 14.2 5.1e-36 123.7 8.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 KII83651.1 - 0.0013 19.2 0.5 0.0013 19.2 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Sensor PF13796.6 KII83651.1 - 0.0083 16.2 1.8 0.075 13.1 0.1 2.5 2 0 0 2 2 2 1 Putative sensor YSIRK_signal PF04650.17 KII83651.1 - 0.17 11.8 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 YSIRK type signal peptide Orf78 PF06024.12 KII83651.1 - 0.21 11.9 1.4 0.47 10.8 0.1 2.2 3 0 0 3 3 3 0 Orf78 (ac78) IL17_R_N PF15037.6 KII83652.1 - 0.0012 17.9 0.1 0.0014 17.7 0.1 1.0 1 0 0 1 1 1 1 Interleukin-17 receptor extracellular region YabA PF06156.13 KII83654.1 - 0.0032 18.1 0.2 0.0063 17.1 0.2 1.4 1 0 0 1 1 1 1 Initiation control protein YabA DUF4525 PF15027.6 KII83654.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Transposase_21 PF02992.14 KII83655.1 - 8e-06 25.3 0.0 3.3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 KII83655.1 - 0.0022 17.6 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Aminotran_3 PF00202.21 KII83657.1 - 3e-107 358.8 0.0 3.4e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KII83657.1 - 0.0084 15.4 0.0 0.026 13.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KII83657.1 - 0.0094 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II F-box-like PF12937.7 KII83658.1 - 1.6e-07 31.1 1.1 3.3e-07 30.1 1.1 1.6 1 1 0 1 1 1 1 F-box-like HHH_9 PF17674.1 KII83658.1 - 0.1 13.5 0.0 0.16 12.9 0.0 1.2 1 0 0 1 1 1 0 HHH domain DUF4150 PF13665.6 KII83659.1 - 0.0048 17.0 0.3 0.07 13.3 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4150) CTP_transf_like PF01467.26 KII83660.1 - 1e-24 87.4 0.0 1.8e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Amidohydro_3 PF07969.11 KII83661.1 - 3e-84 284.2 0.1 3.6e-84 283.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KII83661.1 - 3.4e-10 39.8 0.1 6.9e-05 22.3 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Histone PF00125.24 KII83662.1 - 5.2e-19 68.9 0.0 6.6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KII83662.1 - 4.9e-10 39.0 0.1 9.9e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KII83662.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 KII83663.1 - 6.4e-64 211.9 4.5 4.8e-21 74.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII83663.1 - 0.05 12.8 2.4 0.33 10.1 0.0 2.7 3 1 0 3 3 3 0 Gammaproteobacterial serine protease DUF4574 PF15141.6 KII83663.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Tmemb_14 PF03647.13 KII83663.1 - 0.21 12.3 2.6 9.2 7.1 0.1 3.1 2 2 0 2 2 2 0 Transmembrane proteins 14C GMC_oxred_N PF00732.19 KII83664.1 - 5.6e-64 216.3 0.0 8e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII83664.1 - 3.6e-34 118.4 0.0 6.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII83664.1 - 4.1e-06 26.1 0.1 6.1e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KII83664.1 - 0.0017 17.7 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KII83664.1 - 0.0058 15.8 1.3 0.03 13.4 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII83664.1 - 0.048 12.9 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII83664.1 - 0.19 10.4 0.6 0.28 9.9 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Transposase_21 PF02992.14 KII83669.1 - 3.4e-07 29.7 0.0 5.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KII83669.1 - 0.00026 20.6 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Auto_anti-p27 PF06677.12 KII83669.1 - 0.036 14.2 1.4 3.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cwf_Cwc_15 PF04889.12 KII83669.1 - 0.31 10.7 3.0 0.6 9.8 3.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_3 PF13920.6 KII83669.1 - 0.43 10.5 12.6 0.38 10.7 3.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KII83669.1 - 0.53 10.3 6.2 3.1 7.9 0.8 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 KII83669.1 - 2.4 8.2 8.3 1.1 9.3 0.5 2.5 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type HEM4 PF02602.15 KII83671.1 - 6.1e-38 130.5 0.0 7e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Zn_clus PF00172.18 KII83672.1 - 1.5e-05 25.0 8.2 3.8e-05 23.7 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII83672.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SKN1 PF03935.15 KII83673.1 - 4.9e-187 622.3 0.1 5.7e-187 622.1 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Lyase_1 PF00206.20 KII83674.1 - 3.6e-22 79.2 0.0 5.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KII83674.1 - 8.5e-19 67.9 0.0 2.8e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.25 KII83675.1 - 2.8e-71 240.0 0.0 4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83675.1 - 5.6e-39 134.0 0.0 8.9e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII83675.1 - 7.9e-07 28.7 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KII83675.1 - 4.7e-05 23.1 0.0 9.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KII83675.1 - 0.0038 16.2 0.4 0.0077 15.2 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KII83675.1 - 0.0057 16.3 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KII83675.1 - 0.1 12.5 1.9 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.11 KII83675.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 Phage T7 capsid assembly protein Integrase_H2C2 PF17921.1 KII83676.1 - 1.7e-07 31.2 1.0 3.3e-07 30.3 1.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KII83676.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 H2C2 zinc finger 3Beta_HSD PF01073.19 KII83677.1 - 5.3e-59 199.5 0.0 6.3e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII83677.1 - 2e-34 119.2 0.0 2.3e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII83677.1 - 2e-21 76.8 0.1 7.9e-18 64.9 0.1 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII83677.1 - 1e-12 48.3 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII83677.1 - 3e-11 43.0 2.1 1.7e-08 33.9 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KII83677.1 - 2.8e-09 36.5 0.0 3.8e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KII83677.1 - 5e-07 29.2 3.3 2.2e-06 27.0 3.3 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KII83677.1 - 0.00098 18.7 1.1 0.0017 18.0 1.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KII83677.1 - 0.012 15.5 7.7 1.9 8.3 7.7 2.8 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.18 KII83677.1 - 0.064 13.5 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Bee_toxin PF17454.2 KII83679.1 - 0.12 12.5 0.5 0.3 11.1 0.5 1.7 1 0 0 1 1 1 0 Honey bee toxin Adaptin_N PF01602.20 KII83680.1 - 3.8e-143 477.8 4.9 4.9e-143 477.5 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KII83680.1 - 1.4e-60 204.0 2.8 2.8e-59 199.8 0.3 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII83680.1 - 5.2e-18 65.2 3.7 2.7e-06 27.7 0.0 6.1 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.22 KII83680.1 - 7.3e-12 44.5 6.3 0.00022 21.2 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KII83680.1 - 1.8e-07 31.5 1.9 0.69 10.5 0.1 5.8 5 1 1 6 6 6 3 HEAT-like repeat CLASP_N PF12348.8 KII83680.1 - 0.00029 20.5 0.1 0.16 11.5 0.0 3.2 2 1 0 2 2 2 2 CLASP N terminal RTP1_C1 PF10363.9 KII83680.1 - 0.00029 21.0 0.9 0.4 10.9 0.0 4.1 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KII83680.1 - 0.014 15.4 6.0 3.5 7.8 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KII83680.1 - 0.025 14.5 0.7 0.16 11.8 0.1 2.4 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_hydro_30 PF02055.16 KII83681.1 - 3.6e-25 88.7 1.1 5.3e-25 88.1 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KII83681.1 - 8.4e-15 54.8 0.2 1.3e-14 54.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KII83681.1 - 0.0036 16.9 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 KII83682.1 - 3.2e-24 85.5 0.8 4.5e-24 85.1 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KII83682.1 - 1.9e-16 60.2 0.1 2.8e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 PUD1_2 PF18457.1 KII83682.1 - 0.021 14.8 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 Glyco_hydr_30_2 PF14587.6 KII83682.1 - 0.026 14.1 0.0 0.48 10.0 0.0 2.3 1 1 0 1 1 1 0 O-Glycosyl hydrolase family 30 RNA_pol PF00940.19 KII83683.1 - 3.2e-180 599.4 0.0 4.7e-180 598.8 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KII83683.1 - 3.5e-95 319.2 1.5 5.2e-95 318.7 1.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal ATP_sub_h PF10775.9 KII83684.1 - 1.4e-25 89.1 1.1 2.1e-25 88.5 1.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h IATP PF04568.12 KII83685.1 - 3.4e-06 27.4 4.6 3.8e-06 27.2 4.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP APG6_N PF17675.1 KII83685.1 - 0.068 13.7 8.0 0.077 13.5 8.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4012 PF13196.6 KII83686.1 - 0.17 12.3 1.2 0.32 11.4 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4012) DZR PF12773.7 KII83686.1 - 1.4 9.0 12.8 3.2 7.8 12.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon GCV_T_C PF08669.11 KII83687.1 - 0.025 14.5 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain F-box-like PF12937.7 KII83691.1 - 0.023 14.6 0.2 0.096 12.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like GBR_NSP5 PF17580.2 KII83692.1 - 0.023 14.5 2.1 0.041 13.7 2.1 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Aldo_ket_red PF00248.21 KII83693.1 - 8.2e-47 159.8 0.0 9.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PheRS_DBD1 PF18552.1 KII83693.1 - 0.0021 17.7 0.1 0.0072 16.1 0.0 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 1 HOOK PF05622.12 KII83696.1 - 0.0099 14.1 0.9 0.014 13.6 0.9 1.1 1 0 0 1 1 1 1 HOOK protein DUF3450 PF11932.8 KII83696.1 - 0.046 13.0 1.3 0.068 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 KII83696.1 - 0.14 12.1 0.4 0.32 10.9 0.4 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ATG16 PF08614.11 KII83696.1 - 0.22 11.7 5.1 0.52 10.5 4.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KII83696.1 - 0.24 12.1 2.2 0.79 10.4 2.2 2.0 1 0 0 1 1 1 0 SlyX CENP-F_N PF10481.9 KII83696.1 - 0.31 10.6 4.6 0.11 12.2 0.9 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain Seryl_tRNA_N PF02403.22 KII83696.1 - 0.31 11.3 1.3 0.54 10.5 1.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 KII83696.1 - 0.36 10.9 0.6 0.57 10.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MCC-bdg_PDZ PF10506.9 KII83696.1 - 0.46 10.5 1.4 0.98 9.5 1.4 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_DNA_bd PF12329.8 KII83696.1 - 0.57 10.2 5.1 5.7 7.0 0.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 KII83696.1 - 0.9 9.6 4.5 1.5 8.9 4.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3808 PF10300.9 KII83697.1 - 1.3e-81 274.8 0.0 1.9e-81 274.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KII83697.1 - 0.00022 21.8 0.7 1.5 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII83697.1 - 0.00047 20.4 0.6 0.02 15.2 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII83697.1 - 0.00048 20.7 0.2 3.2 8.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII83697.1 - 0.00069 19.5 8.6 0.0047 16.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII83697.1 - 0.0015 18.5 0.2 0.02 14.9 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII83697.1 - 0.0043 16.8 0.1 0.017 14.9 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII83697.1 - 0.0081 16.3 2.0 0.11 12.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII83697.1 - 0.023 15.3 0.2 4 8.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KII83697.1 - 0.083 13.6 7.0 0.18 12.5 0.5 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KII83697.1 - 0.096 13.2 0.1 3 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sensor PF13796.6 KII83698.1 - 0.00048 20.2 18.1 0.002 18.2 16.1 2.7 1 1 0 1 1 1 1 Putative sensor Aminotran_5 PF00266.19 KII83699.1 - 5.2e-40 137.5 0.0 7.6e-40 137.0 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class-V FHA PF00498.26 KII83700.1 - 2.8e-16 59.6 0.0 5.6e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KII83700.1 - 0.0038 17.5 0.0 0.0095 16.2 0.0 1.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain TRAF_BIRC3_bd PF16673.5 KII83701.1 - 0.076 12.8 0.1 0.076 12.8 0.1 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 KII83701.1 - 0.12 12.5 2.5 0.17 11.9 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3277 PF11681.8 KII83701.1 - 0.16 11.9 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Baculo_PEP_C PF04513.12 KII83701.1 - 0.42 10.7 3.0 2.1 8.4 2.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SMN PF06003.12 KII83701.1 - 0.64 9.2 3.2 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) NPV_P10 PF05531.12 KII83701.1 - 1.2 9.6 3.4 2.3 8.7 1.3 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 KII83701.1 - 3.9 7.8 8.1 7.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Cwf_Cwc_15 PF04889.12 KII83701.1 - 6.9 6.3 15.4 0.55 9.9 10.1 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 KII83701.1 - 7.2 5.0 5.2 14 4.1 5.2 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BTB PF00651.31 KII83702.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain NAD_binding_10 PF13460.6 KII83703.1 - 4.3e-31 108.2 0.4 5.2e-31 108.0 0.4 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KII83703.1 - 0.00047 20.3 0.9 0.066 13.3 0.1 2.2 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 KII83703.1 - 0.02 14.5 0.2 0.044 13.3 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family Semialdhyde_dh PF01118.24 KII83703.1 - 0.021 15.3 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KII83704.1 - 1.2e-20 73.9 0.0 7.1e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII83704.1 - 3.2e-13 49.8 0.0 1.3e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII83704.1 - 3.5e-05 23.8 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII83704.1 - 0.0031 17.2 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII83704.1 - 0.066 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KII83705.1 - 3.2e-38 131.6 50.0 2.1e-37 128.9 45.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII83705.1 - 4.7e-11 42.2 5.6 4.7e-11 42.2 5.6 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KII83705.1 - 1.1e-07 31.5 3.7 1.1e-07 31.5 3.7 2.2 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF1799 PF08809.11 KII83705.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) SET PF00856.28 KII83706.1 - 2.7e-09 37.7 0.0 4.3e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 SET domain DUF5315 PF17242.2 KII83708.1 - 0.085 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) TetR_C_13 PF16925.5 KII83711.1 - 0.054 13.4 0.7 0.16 11.9 0.0 2.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SKG6 PF08693.10 KII83713.1 - 0.00022 20.5 0.5 0.00049 19.5 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 KII83713.1 - 0.024 14.8 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Pkinase_Tyr PF07714.17 KII83716.1 - 0.095 12.0 0.0 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase ADH_zinc_N PF00107.26 KII83718.1 - 6.2e-13 48.9 0.7 1.2e-12 48.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII83718.1 - 2.4e-05 24.1 0.2 7.7e-05 22.5 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII83718.1 - 0.017 16.2 0.0 0.031 15.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII83719.1 - 6.3e-15 55.3 0.1 1.1e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII83719.1 - 4.5e-06 27.7 0.0 8.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII83719.1 - 7.1e-05 22.7 0.1 0.00018 21.3 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KII83719.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DivIC PF04977.15 KII83720.1 - 0.00077 19.2 2.5 0.69 9.7 1.0 2.1 2 0 0 2 2 2 2 Septum formation initiator ATG16 PF08614.11 KII83720.1 - 0.0027 18.0 2.1 0.0034 17.7 2.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 KII83720.1 - 0.0087 16.5 1.0 0.96 9.9 0.1 2.1 2 0 0 2 2 2 1 Cell division protein ZapB Rab_bind PF16704.5 KII83720.1 - 0.013 15.5 1.4 0.059 13.4 0.6 2.1 1 1 1 2 2 2 0 Rab binding domain DMPK_coil PF08826.10 KII83720.1 - 0.016 15.3 1.6 0.037 14.1 1.3 1.8 1 1 0 1 1 1 0 DMPK coiled coil domain like TSC22 PF01166.18 KII83720.1 - 0.025 14.9 1.2 0.14 12.5 0.2 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 KII83720.1 - 0.033 14.4 0.3 2 8.7 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper PikAIV_N PF18605.1 KII83720.1 - 0.04 13.5 4.6 2 8.0 0.3 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain KASH_CCD PF14662.6 KII83720.1 - 0.04 13.7 2.8 0.73 9.6 0.2 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PCRF PF03462.18 KII83720.1 - 0.07 13.0 0.7 0.078 12.8 0.7 1.0 1 0 0 1 1 1 0 PCRF domain SlyX PF04102.12 KII83720.1 - 0.08 13.6 3.2 0.11 13.1 0.9 1.9 1 1 1 2 2 2 0 SlyX BRCC36_C PF18110.1 KII83720.1 - 0.081 13.1 1.5 3.7 7.8 0.2 2.2 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain ADIP PF11559.8 KII83720.1 - 0.16 12.1 3.6 0.65 10.1 0.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KII83720.1 - 0.24 11.5 3.4 0.6 10.2 3.5 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 KII83720.1 - 0.47 10.6 3.7 0.49 10.6 0.4 2.0 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 TLD PF07534.16 KII83721.1 - 9e-30 103.7 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 TLD Ferric_reduct PF01794.19 KII83722.1 - 1.2e-20 73.9 8.3 2.4e-20 72.9 8.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KII83722.1 - 2.9e-11 43.8 0.0 8.3e-11 42.2 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII83722.1 - 1.9e-07 31.1 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain SdpI PF13630.6 KII83722.1 - 2.5 8.3 11.8 0.46 10.6 3.8 3.3 2 1 0 2 2 2 0 SdpI/YhfL protein family DUF805 PF05656.14 KII83722.1 - 2.6 8.5 6.3 26 5.3 1.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Ctr PF04145.15 KII83723.1 - 8.3e-28 97.9 0.1 1e-27 97.6 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DnaJ PF00226.31 KII83724.1 - 8.9e-16 57.8 0.1 1.5e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 KII83725.1 - 5.9e-13 48.7 0.5 5.9e-13 48.7 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain T2SSF PF00482.23 KII83725.1 - 3.6 7.6 5.6 11 5.9 5.6 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HSP70 PF00012.20 KII83725.1 - 6.7 4.8 12.1 12 4.0 12.1 1.3 1 0 0 1 1 1 0 Hsp70 protein Baculo_PEP_C PF04513.12 KII83726.1 - 0.064 13.3 7.6 0.055 13.5 5.6 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Xan_ur_permease PF00860.20 KII83727.1 - 1.1e-55 188.9 32.8 1.1e-55 188.9 32.8 2.2 2 1 0 2 2 2 1 Permease family TauD PF02668.16 KII83728.1 - 5.6e-33 114.9 0.1 9e-33 114.2 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.31 KII83729.1 - 1.3e-12 47.7 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain SANT_DAMP1_like PF16282.5 KII83729.1 - 0.026 14.7 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 O-FucT PF10250.9 KII83730.1 - 2e-10 40.9 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase YusW PF14039.6 KII83733.1 - 0.072 13.6 0.6 0.12 12.9 0.6 1.3 1 0 0 1 1 1 0 YusW-like protein DUF1765 PF08578.10 KII83733.1 - 0.079 13.4 0.0 0.089 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) CAF1A PF12253.8 KII83734.1 - 0.94 9.7 4.6 1.6 8.9 4.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A BTB PF00651.31 KII83735.1 - 0.0052 17.0 0.1 0.017 15.4 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.26 KII83737.1 - 2.3e-11 43.8 0.1 4.3e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII83737.1 - 5e-07 29.6 0.0 1.2e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII83737.1 - 0.0092 17.0 0.0 0.016 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SKG6 PF08693.10 KII83745.1 - 0.025 14.0 0.2 0.025 14.0 0.2 3.5 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KII83745.1 - 0.042 13.6 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KII83745.1 - 0.11 13.3 0.2 0.36 11.7 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mcm10 PF09332.11 KII83745.1 - 0.27 10.6 8.0 0.39 10.1 8.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor NPR3 PF03666.13 KII83745.1 - 0.34 9.7 9.0 0.46 9.2 9.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 KII83745.1 - 2.2 7.0 21.9 3.5 6.4 21.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5305 PF17231.2 KII83745.1 - 4.7 6.5 10.6 7.5 5.9 10.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) B56 PF01603.20 KII83746.1 - 7.1e-187 621.5 1.8 8.3e-187 621.2 1.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) zf-MYND PF01753.18 KII83747.1 - 4.5e-10 39.5 13.9 7.7e-10 38.7 13.9 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 KII83747.1 - 5.7e-09 36.3 2.1 0.023 15.3 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII83747.1 - 1.8e-05 25.3 0.1 4.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KII83747.1 - 8.5e-05 22.8 3.0 0.72 10.2 0.2 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KII83747.1 - 0.00061 20.1 6.2 0.1 13.1 1.5 3.8 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KII83747.1 - 0.0018 18.6 0.3 0.97 10.2 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat zf-C6H2 PF15801.5 KII83747.1 - 0.13 12.6 6.9 0.25 11.7 6.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FlhE PF06366.13 KII83748.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein FlhE Cep57_CLD_2 PF14197.6 KII83749.1 - 0.12 12.5 5.0 0.24 11.5 5.0 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 KII83749.1 - 2.4 6.6 8.7 5.2 5.5 8.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family KDZ PF18758.1 KII83750.1 - 2.1e-18 66.8 0.1 2.8e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII83750.1 - 1.2e-06 28.6 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII83750.1 - 5.7e-05 23.2 0.0 9.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII83751.1 - 1.8e-35 122.6 0.0 2.2e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF4747 PF15931.5 KII83752.1 - 0.27 10.9 0.0 0.39 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) Glyco_transf_20 PF00982.21 KII83753.1 - 2.4e-28 99.0 0.5 2.7e-28 98.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 SIP PF04954.13 KII83757.1 - 0.031 14.8 0.6 0.082 13.4 0.6 1.6 1 0 0 1 1 1 0 Siderophore-interacting protein F-box-like PF12937.7 KII83757.1 - 0.085 12.8 0.3 0.21 11.5 0.3 1.7 1 0 0 1 1 1 0 F-box-like DnaJ PF00226.31 KII83758.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain 4HBT_2 PF13279.6 KII83759.1 - 5.8e-07 30.0 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Phage_ASH PF10554.9 KII83759.1 - 0.085 13.2 2.6 0.13 12.6 0.7 2.2 2 0 0 2 2 2 0 Ash protein family ABC_tran PF00005.27 KII83760.1 - 1.5e-48 164.8 0.0 5.9e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII83760.1 - 5.5e-41 141.0 27.8 3.8e-21 76.0 10.5 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region T2SSE PF00437.20 KII83760.1 - 3.8e-07 29.5 0.1 0.0039 16.3 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 KII83760.1 - 3.8e-06 26.6 0.1 0.0014 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KII83760.1 - 6.2e-06 25.8 0.0 0.17 11.3 0.0 4.0 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KII83760.1 - 1.4e-05 25.1 2.6 0.85 9.4 0.1 4.2 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KII83760.1 - 8.3e-05 23.0 0.0 0.31 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KII83760.1 - 0.00018 22.1 0.1 0.026 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII83760.1 - 0.00021 21.0 0.3 0.55 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KII83760.1 - 0.0012 19.0 0.1 0.0025 17.9 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KII83760.1 - 0.032 14.5 0.6 19 5.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KII83760.1 - 0.083 12.9 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 KII83760.1 - 0.084 13.0 0.4 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KII83760.1 - 0.14 11.5 0.1 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KII83760.1 - 0.2 11.2 0.1 13 5.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MFS_1 PF07690.16 KII83762.1 - 1.4e-42 146.0 66.6 3.6e-32 111.7 31.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2976 PF11190.8 KII83762.1 - 0.025 14.3 0.4 0.025 14.3 0.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2976) O-FucT PF10250.9 KII83763.1 - 0.0038 17.0 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPR_16 PF13432.6 KII83764.1 - 2.5e-12 47.2 16.7 0.0035 17.9 0.0 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII83764.1 - 3.6e-11 43.4 14.9 0.006 17.1 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII83764.1 - 5.8e-11 41.6 21.6 0.14 12.4 0.1 10.1 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KII83764.1 - 3.6e-08 33.5 0.9 1.2 10.0 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII83764.1 - 9.8e-08 31.6 8.2 0.032 13.9 0.1 6.0 6 0 0 6 6 6 2 TPR repeat TPR_14 PF13428.6 KII83764.1 - 3.3e-07 30.6 29.9 0.038 14.8 0.2 10.3 8 3 4 12 12 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII83764.1 - 6.7e-07 28.9 6.7 0.086 12.9 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII83764.1 - 1.6e-06 28.1 2.6 1.5 9.4 0.1 5.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII83764.1 - 1.7e-06 28.2 30.3 0.00099 19.4 0.7 8.2 9 2 1 10 10 9 3 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KII83764.1 - 0.00022 21.7 0.3 0.8 10.1 0.0 3.4 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_8 PF13181.6 KII83764.1 - 0.00025 21.0 11.9 11 6.5 0.0 9.4 13 0 0 13 13 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 KII83764.1 - 0.00057 20.2 10.8 0.081 13.3 0.2 5.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KII83764.1 - 0.002 18.2 16.4 0.0069 16.5 0.3 5.1 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII83764.1 - 0.0026 17.5 14.6 0.19 11.6 0.0 7.0 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF2225 PF09986.9 KII83764.1 - 0.013 15.2 0.3 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC3 PF12895.7 KII83764.1 - 0.15 12.3 0.1 0.15 12.3 0.1 4.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KII83764.1 - 0.18 11.7 5.5 23 5.0 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KII83764.1 - 0.3 10.5 5.7 0.19 11.1 0.4 2.9 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP ANAPC5 PF12862.7 KII83764.1 - 0.55 10.3 3.8 15 5.7 0.0 4.2 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 NARP1 PF12569.8 KII83764.1 - 0.8 8.5 6.3 0.62 8.9 0.6 2.7 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 EndoU_bacteria PF14436.6 KII83767.1 - 0.0072 16.7 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial EndoU nuclease Chitin_bind_4 PF00379.23 KII83767.1 - 0.18 12.4 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 Insect cuticle protein Auxin_repressed PF05564.12 KII83767.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.3 3 2 0 3 3 3 0 Dormancy/auxin associated protein p450 PF00067.22 KII83768.1 - 8.2e-65 219.3 0.0 4.5e-52 177.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Gti1_Pac2 PF09729.9 KII83771.1 - 9.4e-30 104.0 0.3 7.1e-26 91.4 0.1 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family SPX PF03105.19 KII83771.1 - 0.066 13.1 1.3 0.11 12.5 1.3 1.3 1 1 0 1 1 1 0 SPX domain Pkinase_Tyr PF07714.17 KII83772.1 - 3e-50 170.9 0.0 5.4e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII83772.1 - 6.1e-40 137.3 0.0 2.1e-39 135.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KII83772.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII83772.1 - 0.0019 17.8 0.4 0.004 16.8 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KII83772.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family MtmB PF05369.12 KII83772.1 - 0.052 12.4 0.0 0.081 11.7 0.0 1.2 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Aldo_ket_red PF00248.21 KII83773.1 - 1e-47 162.8 0.0 1.7e-36 125.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Methyltransf_22 PF13383.6 KII83775.1 - 2.8e-23 82.8 0.0 3.5e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KII83775.1 - 3.9e-07 30.3 0.0 5.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 KII83776.1 - 6.9e-23 81.5 0.0 8.7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KII83776.1 - 1.7e-07 31.4 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain MARVEL PF01284.23 KII83777.1 - 0.0094 16.0 7.9 0.02 14.9 7.9 1.6 1 1 0 1 1 1 1 Membrane-associating domain F-box-like PF12937.7 KII83778.1 - 0.00053 19.8 2.0 0.0024 17.8 0.3 2.7 2 0 0 2 2 2 1 F-box-like Dynamitin PF04912.14 KII83778.1 - 0.39 10.0 0.6 3.6 6.8 0.2 2.1 2 0 0 2 2 2 0 Dynamitin AA_permease PF00324.21 KII83780.1 - 4.9e-125 417.8 36.5 6e-125 417.6 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII83780.1 - 4.6e-31 108.1 41.6 5.7e-31 107.8 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.7 KII83781.1 - 1e-15 59.0 1.9 1.3e-15 58.7 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII83781.1 - 0.026 14.2 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 KII83781.1 - 0.068 11.9 0.0 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 Ndr family DGF-1_C PF11040.8 KII83782.1 - 3.4e-05 23.8 0.3 6.9e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF4588 PF15251.6 KII83782.1 - 6.9e-05 22.7 0.1 0.00013 21.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CCDC53 PF10152.9 KII83782.1 - 0.12 12.8 0.9 0.21 12.0 0.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Stm1_N PF09598.10 KII83782.1 - 9.6 7.1 11.0 18 6.2 11.0 1.4 1 0 0 1 1 1 0 Stm1 ABC_tran PF00005.27 KII83783.1 - 4.2e-51 173.1 0.0 1.8e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII83783.1 - 1.5e-46 159.3 27.5 1.2e-21 77.6 10.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KII83783.1 - 3.2e-07 30.0 0.5 0.0048 16.4 0.1 3.9 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KII83783.1 - 3.5e-07 30.3 1.7 0.51 10.1 0.0 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KII83783.1 - 9.1e-07 28.2 0.2 0.0026 16.9 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KII83783.1 - 2.6e-05 23.9 0.3 0.2 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KII83783.1 - 0.00029 21.4 4.8 0.0047 17.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KII83783.1 - 0.00058 19.5 0.1 0.73 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KII83783.1 - 0.00091 19.6 0.2 1.5 9.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KII83783.1 - 0.0045 17.1 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KII83783.1 - 0.016 15.4 0.4 12 6.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KII83783.1 - 0.037 13.7 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KII83783.1 - 0.039 14.0 0.2 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KII83783.1 - 0.051 13.8 0.2 5.4 7.3 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RseC_MucC PF04246.12 KII83783.1 - 0.055 13.4 0.0 0.32 10.9 0.0 2.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AAA_33 PF13671.6 KII83783.1 - 0.079 13.1 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KII83783.1 - 0.15 11.9 0.1 20 5.0 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KII83783.1 - 0.15 11.2 0.1 0.72 9.0 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KII83783.1 - 0.2 11.1 0.1 18 4.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KII83783.1 - 0.54 10.2 1.8 6.7 6.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KII83783.1 - 0.54 10.3 1.9 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Metallophos PF00149.28 KII83786.1 - 7.3e-36 124.6 0.0 9.4e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KII83786.1 - 0.00013 21.7 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KII83786.1 - 0.032 14.7 0.1 0.083 13.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KII83786.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EMC1_C PF07774.13 KII83787.1 - 6.7e-77 258.0 0.3 1.2e-76 257.2 0.3 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KII83787.1 - 2.8e-14 53.3 3.5 4.5e-09 36.2 0.4 3.3 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KII83787.1 - 2.6e-11 42.9 0.2 0.0006 19.6 0.0 5.5 5 0 0 5 5 5 3 PQQ enzyme repeat ApoO PF09769.9 KII83788.1 - 6.1e-28 97.4 0.1 2.5e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 Apolipoprotein O Phasin PF05597.11 KII83788.1 - 0.0085 16.1 4.9 2.4 8.1 1.0 3.0 2 1 1 3 3 3 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Mitoc_L55 PF09776.9 KII83789.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L55 SNF2_N PF00176.23 KII83790.1 - 1.8e-54 184.8 0.1 3.2e-54 184.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII83790.1 - 7.1e-16 58.5 0.0 1.9e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 KII83790.1 - 1.3e-05 25.0 20.4 0.00024 20.9 3.7 3.3 3 0 0 3 3 3 2 PHD-finger DEAD PF00270.29 KII83790.1 - 2.5e-05 24.1 0.0 5.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase C1_1 PF00130.22 KII83790.1 - 0.015 15.2 1.9 0.015 15.2 1.9 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.12 KII83790.1 - 0.49 10.7 11.4 7.7 6.8 8.9 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain zf-PHD-like PF15446.6 KII83790.1 - 0.99 9.0 10.5 0.36 10.5 0.9 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain NOA36 PF06524.12 KII83790.1 - 2.5 7.4 15.6 3.3 6.9 12.1 2.3 1 1 1 2 2 2 0 NOA36 protein Peptidase_M36 PF02128.15 KII83791.1 - 3.4e-139 464.1 9.0 4.4e-139 463.8 9.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) PepSY PF03413.19 KII83791.1 - 0.00062 20.3 0.1 0.0014 19.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain FTP PF07504.13 KII83791.1 - 0.00062 19.5 3.0 0.0013 18.5 0.4 2.6 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KII83791.1 - 0.012 15.5 0.1 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain DUF1202 PF06717.11 KII83791.1 - 0.11 11.8 0.8 0.17 11.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Misat_Tub_SegII PF10644.9 KII83792.1 - 9e-34 116.3 0.0 2.9e-33 114.7 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KII83792.1 - 1.8e-33 115.8 0.2 3.7e-33 114.7 0.2 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 KII83792.1 - 0.00017 21.8 0.0 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain TMEM154 PF15102.6 KII83793.1 - 0.14 12.0 0.8 0.24 11.3 0.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family Glyco_transf_20 PF00982.21 KII83794.1 - 4.1e-142 474.2 0.0 5.6e-142 473.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KII83794.1 - 1.1e-25 90.1 0.0 1.4e-24 86.5 0.0 2.2 2 0 0 2 2 2 1 Trehalose-phosphatase SRP-alpha_N PF04086.13 KII83795.1 - 4.8 7.0 13.9 7 6.5 13.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.25 KII83796.1 - 0.2 11.0 0.1 0.34 10.2 0.1 1.4 1 1 0 1 1 1 0 Protein kinase domain Alpha-amyl_C2 PF07821.12 KII83797.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain AA_permease PF00324.21 KII83798.1 - 1.1e-126 423.3 33.0 1.3e-126 423.1 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII83798.1 - 2.9e-31 108.8 36.7 3.9e-31 108.3 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1180 PF06679.12 KII83799.1 - 0.047 14.1 0.9 0.047 14.1 0.9 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) EptA_B_N PF08019.12 KII83799.1 - 0.053 13.4 0.2 0.077 12.9 0.2 1.2 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF2207 PF09972.9 KII83799.1 - 0.07 11.9 0.0 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3810 PF12725.7 KII83799.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Ribosomal_S19 PF00203.21 KII83800.1 - 1.4e-24 85.8 0.0 1.7e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Pkinase PF00069.25 KII83801.1 - 1.4e-73 247.5 0.3 1.4e-73 247.5 0.3 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83801.1 - 3.6e-52 177.2 0.2 3.6e-52 177.2 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KII83801.1 - 4.5e-24 84.6 0.0 1.2e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Haspin_kinase PF12330.8 KII83801.1 - 4.7e-06 25.8 0.3 7.2e-06 25.2 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KII83801.1 - 6.7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII83801.1 - 1.6e-05 23.8 0.0 3.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PH PF00169.29 KII83801.1 - 2.7e-05 24.6 0.6 6.2e-05 23.5 0.1 1.8 2 0 0 2 2 1 1 PH domain APH PF01636.23 KII83801.1 - 0.0034 17.3 6.7 0.011 15.7 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PRP38_assoc PF12871.7 KII83801.1 - 0.0094 16.5 27.0 0.026 15.1 27.0 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 PF13054.6 KII83801.1 - 0.021 14.8 11.7 0.046 13.7 11.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Rrn6 PF10214.9 KII83801.1 - 0.46 8.9 7.9 0.8 8.1 7.9 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 KII83801.1 - 0.74 8.0 2.7 1.1 7.5 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 KII83801.1 - 1.4 8.0 9.1 2.2 7.3 9.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CNOT11 PF10155.9 KII83802.1 - 2.9e-14 53.3 0.0 4.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 GATase_6 PF13522.6 KII83803.1 - 1.2e-13 51.4 0.0 2.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KII83803.1 - 3.6e-08 32.6 0.1 1.9e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II DUF3172 PF11371.8 KII83803.1 - 0.013 15.2 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) ThuA PF06283.11 KII83803.1 - 0.022 15.0 0.0 0.2 11.9 0.0 2.3 2 1 0 2 2 2 0 Trehalose utilisation GATase_7 PF13537.6 KII83803.1 - 0.042 13.7 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Trypan_PARP PF05887.11 KII83806.1 - 4.4 7.3 15.4 0.83 9.6 7.9 2.6 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_3 PF07859.13 KII83807.1 - 6.8e-19 68.6 0.0 9.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII83807.1 - 1.9e-07 30.3 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3593 PF12159.8 KII83808.1 - 1.6 8.8 4.9 0.21 11.6 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) PGG PF13962.6 KII83809.1 - 0.015 15.1 0.9 0.034 14.0 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function STE3 PF02076.15 KII83813.1 - 6.5e-111 370.2 19.8 7.5e-111 370.0 19.8 1.0 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 KII83813.1 - 1.9 8.3 3.7 2.1 8.2 2.6 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Abhydrolase_9_N PF15420.6 KII83813.1 - 5.7 6.9 7.9 2.9 7.8 2.9 2.6 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus Pheromone PF08015.11 KII83814.1 - 1e-06 29.6 3.6 2e-06 28.7 3.6 1.5 1 1 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 KII83815.1 - 1.7e-113 378.7 23.9 1.9e-113 378.5 23.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.11 KII83817.1 - 0.0018 19.2 2.0 0.0018 19.2 2.0 2.3 2 1 0 2 2 2 1 Fungal mating-type pheromone Pheromone PF08015.11 KII83818.1 - 9.3e-05 23.4 3.3 0.00016 22.6 3.3 1.4 1 1 0 1 1 1 1 Fungal mating-type pheromone MMPL PF03176.15 KII83819.1 - 0.03 13.3 0.8 0.032 13.1 0.8 1.0 1 0 0 1 1 1 0 MMPL family STE3 PF02076.15 KII83820.1 - 6.8e-117 389.8 18.8 8.1e-117 389.5 18.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.11 KII83821.1 - 1.3e-08 35.8 0.7 1.5e-08 35.5 0.7 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 KII83822.1 - 1.7e-95 319.6 19.2 2e-95 319.4 19.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor FAM70 PF14967.6 KII83822.1 - 0.032 13.7 1.0 0.049 13.1 0.1 1.7 2 0 0 2 2 2 0 FAM70 protein DUF1129 PF06570.11 KII83825.1 - 8.4 5.8 9.2 3.5 7.1 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2628 PF10947.8 KII83826.1 - 7.3 7.0 10.7 0.49 10.8 3.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2628) TraP PF07296.11 KII83829.1 - 0.00077 18.7 1.4 0.0012 18.0 1.4 1.3 1 0 0 1 1 1 1 TraP protein Lenti_VIF_2 PF07401.12 KII83831.1 - 0.0031 16.9 2.4 0.082 12.2 1.0 2.6 1 1 1 2 2 2 1 Bovine Lentivirus VIF protein RT_RNaseH PF17917.1 KII83833.1 - 0.00069 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF668 PF05003.12 KII83834.1 - 0.022 15.2 0.1 0.049 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) MNSV_P7B PF06692.11 KII83835.1 - 0.068 13.2 0.2 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein BolA PF01722.18 KII83836.1 - 2.6e-17 62.9 0.0 4.9e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein C9orf72-like PF15019.6 KII83836.1 - 0.085 12.4 0.0 0.091 12.3 0.0 1.0 1 0 0 1 1 1 0 C9orf72-like protein family POR PF01558.18 KII83836.1 - 0.12 12.4 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF373 PF04123.13 KII83837.1 - 0.52 9.7 7.3 0.76 9.2 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SLATT_4 PF18186.1 KII83838.1 - 0.92 9.1 3.0 1.8 8.2 0.4 2.3 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Syndecan PF01034.20 KII83840.1 - 0.85 9.6 3.3 2.7 8.0 0.1 3.3 3 0 0 3 3 3 0 Syndecan domain DUF89 PF01937.19 KII83842.1 - 4.2e-72 243.0 0.0 5.3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 4HBT PF03061.22 KII83847.1 - 1.3e-07 31.9 0.0 0.00056 20.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Amino_oxidase PF01593.24 KII83849.1 - 4.7e-68 230.5 0.5 6.2e-66 223.5 0.5 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII83849.1 - 2.4e-11 43.7 0.1 6.2e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KII83849.1 - 0.00016 21.0 0.2 0.00025 20.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KII83849.1 - 0.0014 18.1 0.4 0.0018 17.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KII83849.1 - 0.0019 17.8 0.7 0.0051 16.4 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII83849.1 - 0.0025 17.1 0.0 0.015 14.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII83849.1 - 0.0031 16.6 0.4 0.0053 15.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KII83849.1 - 0.027 13.8 0.2 0.05 12.9 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KII83849.1 - 0.036 13.2 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A B12-binding PF02310.19 KII83849.1 - 0.1 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain HI0933_like PF03486.14 KII83849.1 - 0.12 11.0 0.3 0.18 10.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KII83849.1 - 0.21 10.8 0.3 0.52 9.5 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII83849.1 - 0.23 12.0 2.1 0.6 10.7 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Transp_cyt_pur PF02133.15 KII83850.1 - 2.7e-111 372.5 38.1 3.2e-111 372.2 38.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2374 PF09574.10 KII83850.1 - 0.016 15.0 2.7 7 6.6 2.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Pkinase PF00069.25 KII83851.1 - 1.6e-48 165.4 0.0 2.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83851.1 - 7e-47 159.9 0.0 9.4e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KII83851.1 - 4.1e-07 29.8 1.2 8.1e-07 28.8 1.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 KII83851.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII83851.1 - 0.0027 17.7 0.2 0.0085 16.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family PHD PF00628.29 KII83851.1 - 0.051 13.5 4.1 0.11 12.4 4.1 1.5 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KII83851.1 - 0.095 13.0 0.5 0.19 12.1 0.5 1.5 1 0 0 1 1 1 0 C1 domain Seadorna_VP7 PF07387.11 KII83851.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KII83851.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KII83851.1 - 0.28 10.1 0.0 0.56 9.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain GEN1_C PF18380.1 KII83853.1 - 6e-31 107.5 0.0 6e-31 107.5 0.0 3.0 3 0 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KII83853.1 - 5.1e-19 68.4 0.0 1.3e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KII83853.1 - 0.00024 21.5 0.0 0.00077 19.9 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain MbeB_N PF04837.12 KII83853.1 - 0.061 13.6 0.5 0.48 10.8 0.1 2.3 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Rap_GAP PF02145.15 KII83854.1 - 2.8e-41 141.1 0.0 4.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KII83854.1 - 2e-38 132.4 0.5 5e-35 121.2 0.1 2.5 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 KII83854.1 - 1.8e-08 33.8 0.2 2e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) VHS PF00790.19 KII83855.1 - 5.9e-13 48.9 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KII83855.1 - 4.6e-10 39.7 0.1 8.7e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 GAT domain Presenilin PF01080.17 KII83855.1 - 9.6 4.9 10.4 22 3.7 10.4 1.5 1 0 0 1 1 1 0 Presenilin Glyco_hydro_3 PF00933.21 KII83856.1 - 3.1e-81 273.2 0.0 5e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain RRM_1 PF00076.22 KII83858.1 - 1.9e-34 117.3 0.1 5.5e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII83858.1 - 1.5e-11 44.3 0.1 8.8e-07 29.0 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KII83858.1 - 0.0005 20.0 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KII83858.1 - 0.0046 16.6 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_3 PF08777.11 KII83858.1 - 0.031 14.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif COG7 PF10191.9 KII83859.1 - 3.4e-79 267.0 2.2 2.6e-45 155.0 3.3 3.1 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) SPA PF08616.10 KII83859.1 - 0.01 15.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Stabilization of polarity axis Mpv17_PMP22 PF04117.12 KII83865.1 - 5.3e-22 77.8 0.6 1.1e-21 76.8 0.6 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 KII83865.1 - 0.15 12.4 2.9 0.56 10.6 0.7 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain zinc_ribbon_10 PF10058.9 KII83866.1 - 5.1e-16 58.1 0.7 7.7e-16 57.6 0.7 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein RsdA_SigD_bd PF16751.5 KII83866.1 - 0.077 13.3 0.9 16 5.8 0.1 2.6 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region Zn_Tnp_IS1595 PF12760.7 KII83866.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Pox_F17 PF04767.12 KII83867.1 - 0.49 10.9 3.9 0.36 11.4 0.9 2.4 1 1 2 3 3 3 0 DNA-binding 11 kDa phosphoprotein LRR_4 PF12799.7 KII83868.1 - 0.036 14.5 0.3 61 4.2 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII83868.1 - 9.3 6.1 5.7 20 5.0 0.1 3.8 5 0 0 5 5 5 0 Leucine rich repeat Asp PF00026.23 KII83870.1 - 9e-07 28.6 0.3 2.9e-06 26.9 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease LRR_8 PF13855.6 KII83871.1 - 0.056 13.2 1.6 19 5.1 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat UCH PF00443.29 KII83872.1 - 1.5e-37 129.5 0.0 2.4e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KII83872.1 - 7.9e-25 87.0 11.1 4.3e-20 71.8 0.6 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KII83872.1 - 2.4e-24 84.8 2.8 1.9e-23 82.0 0.3 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KII83872.1 - 2.3e-21 75.3 0.2 6.4e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KII83872.1 - 2.1e-16 60.4 0.0 5.2e-14 52.6 0.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KII83872.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain zf-MYND PF01753.18 KII83873.1 - 5.5e-07 29.6 15.4 5.5e-07 29.6 15.4 4.4 4 0 0 4 4 4 1 MYND finger zf-C6H2 PF15801.5 KII83873.1 - 0.021 15.1 14.0 0.021 15.1 14.0 2.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding F-box PF00646.33 KII83875.1 - 0.003 17.4 0.6 0.03 14.2 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII83875.1 - 0.0039 17.0 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like UPF0016 PF01169.19 KII83877.1 - 6e-44 148.2 18.7 8.7e-23 80.5 6.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KII83877.1 - 0.00037 20.3 8.1 0.0027 17.5 0.1 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump TerC PF03741.16 KII83877.1 - 0.0064 16.2 4.2 0.017 14.8 0.0 2.5 2 1 0 2 2 2 1 Integral membrane protein TerC family LysE PF01810.18 KII83877.1 - 0.0079 15.7 9.9 0.14 11.6 1.5 2.9 2 1 1 3 3 3 2 LysE type translocator DUF3995 PF13160.6 KII83877.1 - 0.17 12.3 8.7 1.8 8.9 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Aldedh PF00171.22 KII83878.1 - 3.5e-185 615.9 0.0 4e-185 615.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KII83878.1 - 0.0016 17.6 0.1 0.008 15.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF5063 PF16702.5 KII83878.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) DUF1487 PF07368.11 KII83878.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Peptidase_C54 PF03416.19 KII83879.1 - 1.8e-103 345.7 0.0 2.5e-103 345.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Ras PF00071.22 KII83882.1 - 8.4e-39 132.8 0.0 7.4e-37 126.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KII83882.1 - 9.6e-30 103.3 0.0 1.6e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII83882.1 - 9e-07 28.5 0.0 2.1e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII83882.1 - 0.0041 16.7 0.0 0.052 13.1 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KII83882.1 - 0.0073 16.4 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Oxidoreduct_C PF16490.5 KII83882.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Gtr1_RagA PF04670.12 KII83882.1 - 0.041 13.2 0.0 0.09 12.1 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KII83882.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII83882.1 - 0.22 11.4 0.1 0.71 9.8 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase LSM PF01423.22 KII83883.1 - 7.5e-18 64.0 0.1 8.6e-18 63.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII83883.1 - 5.9e-05 23.1 0.1 7.2e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DEAD PF00270.29 KII83884.1 - 2.1e-18 66.7 0.0 6.9e-16 58.5 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII83884.1 - 4.7e-11 43.0 0.0 1.2e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII83884.1 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_1 PF00561.20 KII83885.1 - 6.7e-16 58.7 0.0 8.1e-14 51.9 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII83885.1 - 2.3e-15 57.8 0.3 2.8e-15 57.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII83885.1 - 4.6e-08 32.6 0.0 9.9e-08 31.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KII83885.1 - 1.9e-05 24.6 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase DUF915 PF06028.11 KII83885.1 - 0.013 14.8 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 KII83885.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) DUF2834 PF11196.8 KII83887.1 - 6.7e-08 32.8 19.4 0.00074 19.8 2.9 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF2834) F-box PF00646.33 KII83891.1 - 0.016 15.1 0.4 0.016 15.1 0.4 1.8 2 0 0 2 2 2 0 F-box domain Haem_bd PF14376.6 KII83892.1 - 6.3e-05 22.9 0.8 6.3e-05 22.9 0.8 1.9 2 0 0 2 2 2 1 Haem-binding domain F-box PF00646.33 KII83892.1 - 0.0024 17.7 0.2 0.005 16.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain Cytochrome_CBB3 PF13442.6 KII83892.1 - 0.15 12.4 1.1 0.45 10.9 1.1 1.9 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III TauD PF02668.16 KII83896.1 - 1.2e-57 195.7 1.5 1.5e-57 195.4 1.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3106 PF11304.8 KII83896.1 - 0.094 13.2 0.0 9.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) NAP PF00956.18 KII83897.1 - 1.7e-91 306.1 3.2 2.5e-91 305.6 3.2 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) HSP70 PF00012.20 KII83898.1 - 6.1e-64 216.3 5.4 9.3e-45 152.9 0.0 3.3 2 2 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 KII83898.1 - 1.9e-10 40.1 0.0 6.5e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 KII83898.1 - 0.042 12.5 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Actin zf-CCHC PF00098.23 KII83899.1 - 4.4e-05 23.4 1.9 4.4e-05 23.4 1.9 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KII83899.1 - 0.0089 15.7 2.8 0.0089 15.7 2.8 1.8 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KII83899.1 - 0.018 14.9 1.1 0.033 14.0 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 KII83899.1 - 0.042 13.8 0.3 0.086 12.8 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Protamine_P2 PF00841.19 KII83899.1 - 0.37 11.3 4.0 0.62 10.6 0.0 2.8 3 0 0 3 3 3 0 Sperm histone P2 Metal_resist PF13801.6 KII83900.1 - 0.57 10.4 4.6 1.8 8.8 4.5 1.7 1 1 0 1 1 1 0 Heavy-metal resistance DEAD PF00270.29 KII83903.1 - 3.8e-12 46.3 0.0 7e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII83903.1 - 4.3e-10 39.9 0.0 1.3e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII83903.1 - 3.1e-06 27.3 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Epimerase PF01370.21 KII83904.1 - 4.3e-20 72.2 0.0 6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII83904.1 - 1.9e-11 44.0 0.1 2.6e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KII83904.1 - 3e-11 42.9 0.0 4.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII83904.1 - 2.4e-10 40.6 0.8 3.5e-10 40.1 0.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII83904.1 - 2.9e-10 39.7 0.5 1.1e-08 34.6 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KII83904.1 - 5e-07 29.1 0.1 7.4e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KII83904.1 - 7.6e-07 28.9 0.2 3.4e-06 26.8 0.8 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KII83904.1 - 0.0005 20.0 1.3 0.0023 17.9 1.3 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KII83904.1 - 0.0077 15.7 0.1 0.019 14.5 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KII83904.1 - 0.024 13.7 0.3 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.21 KII83905.1 - 4e-14 52.7 3.1 8.4e-08 32.0 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII83905.1 - 1.3e-13 51.1 1.9 3.7e-07 29.9 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KII83905.1 - 4e-08 33.1 3.5 0.00018 21.1 0.3 2.4 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KII83905.1 - 1.7e-06 28.0 3.4 0.00076 19.4 0.1 2.9 2 1 0 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 KII83905.1 - 1.9e-05 23.8 1.0 0.021 13.8 0.3 2.7 2 1 1 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KII83905.1 - 5.3e-05 22.8 0.5 0.038 13.4 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KII83905.1 - 7.3e-05 22.0 0.2 0.061 12.5 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KII83905.1 - 0.00047 19.3 0.2 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.10 KII83905.1 - 0.00078 19.4 3.2 0.81 9.6 0.1 2.6 2 1 0 2 2 2 2 KR domain NAD_binding_4 PF07993.12 KII83905.1 - 0.0015 17.8 4.5 0.41 9.8 0.2 2.8 3 0 0 3 3 3 2 Male sterility protein Ldh_1_N PF00056.23 KII83905.1 - 0.0059 16.7 0.6 0.29 11.2 0.1 2.6 1 1 2 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain Phage_holin_3_3 PF16083.5 KII83905.1 - 0.0089 16.1 0.2 6.6 6.9 0.0 2.5 2 0 0 2 2 2 2 LydA holin phage, holin superfamily III DapB_N PF01113.20 KII83905.1 - 0.0098 16.0 0.1 5.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KII83905.1 - 0.014 14.8 0.3 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KII83905.1 - 0.036 14.3 1.7 39 4.5 0.0 3.1 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HcyBio PF01837.16 KII83905.1 - 0.037 12.9 0.4 0.46 9.3 0.0 2.0 2 0 0 2 2 2 0 Homocysteine biosynthesis enzyme, sulfur-incorporation NAD_binding_2 PF03446.15 KII83905.1 - 0.038 14.2 0.0 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KII83905.1 - 0.078 12.9 0.4 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Integrase_H2C2 PF17921.1 KII83907.1 - 0.17 12.0 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain zf-CCHC PF00098.23 KII83908.1 - 0.43 10.8 2.6 0.85 9.8 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.22 KII83909.1 - 3.4e-69 233.8 0.0 4.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 KII83910.1 - 6.7e-69 231.5 50.0 2e-38 131.9 20.0 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KII83910.1 - 9.5e-38 129.8 0.0 1.5e-18 67.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KII83910.1 - 3.5e-25 87.7 12.9 1.8e-21 75.8 0.1 3.7 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KII83910.1 - 7.3e-08 32.9 0.2 2.2e-07 31.4 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KII83910.1 - 1.9e-06 28.3 0.3 0.0054 17.1 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KII83910.1 - 3e-06 26.9 0.2 0.0021 17.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KII83910.1 - 6.7e-06 26.1 0.0 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KII83910.1 - 8e-05 22.9 0.1 0.087 13.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KII83910.1 - 0.00061 20.3 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII83910.1 - 0.0016 18.2 0.5 0.68 9.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII83910.1 - 0.002 18.2 0.1 0.46 10.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 KII83910.1 - 0.0021 18.0 0.1 0.23 11.4 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KII83910.1 - 0.0021 18.2 0.3 2.8 8.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KII83910.1 - 0.0056 16.4 1.3 2.6 7.7 0.6 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KII83910.1 - 0.0058 16.1 0.0 0.067 12.6 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 KII83910.1 - 0.0063 16.1 0.2 0.12 12.0 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KII83910.1 - 0.0085 15.9 0.1 3.9 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KII83910.1 - 0.01 14.9 0.0 0.86 8.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KII83910.1 - 0.021 14.2 0.1 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KII83910.1 - 0.029 14.9 0.2 0.062 13.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF4129 PF13559.6 KII83910.1 - 0.041 14.1 1.5 11 6.4 0.8 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) TsaE PF02367.17 KII83910.1 - 0.061 13.3 0.5 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 KII83910.1 - 0.074 12.9 0.0 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 KII83910.1 - 0.11 12.9 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KII83910.1 - 0.17 11.6 0.5 23 4.7 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 KII83910.1 - 0.18 12.2 0.1 6.4 7.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain p450 PF00067.22 KII83911.1 - 1e-75 255.3 0.0 1.2e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxysterol_BP PF01237.18 KII83915.1 - 2.4e-137 457.8 0.0 6e-137 456.4 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KII83915.1 - 4.4e-13 49.2 0.5 1.6e-06 28.3 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII83915.1 - 8.5e-11 42.3 0.1 7e-09 36.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PH PF00169.29 KII83915.1 - 2e-10 41.1 0.0 5.8e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 PH domain Ank_3 PF13606.6 KII83915.1 - 1.7e-09 37.1 0.4 0.035 14.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KII83915.1 - 2e-08 34.3 1.3 0.019 15.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KII83915.1 - 1.2e-06 29.0 0.9 0.0022 18.5 0.3 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH_8 PF15409.6 KII83915.1 - 4.1e-05 23.8 0.8 0.00013 22.2 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KII83915.1 - 0.0006 20.2 0.4 0.0021 18.4 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.22 KII83916.1 - 1e-60 205.8 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 KII83917.1 - 4.4e-19 68.6 0.0 5.9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Epimerase PF01370.21 KII83918.1 - 1.9e-18 66.8 0.0 3.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII83918.1 - 3.4e-11 43.1 0.2 8.4e-11 41.8 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII83918.1 - 5.7e-11 42.1 0.6 9.3e-10 38.1 0.6 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KII83918.1 - 1.9e-10 41.0 0.4 2.9e-10 40.3 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII83918.1 - 2.6e-10 39.8 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KII83918.1 - 4.1e-07 29.8 0.5 1.5e-06 27.9 1.3 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII83918.1 - 1.4e-06 27.7 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KII83918.1 - 8.6e-05 22.5 1.4 0.0004 20.3 1.3 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KII83918.1 - 0.0016 17.9 0.2 0.004 16.6 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KII83918.1 - 0.021 13.9 0.1 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain LSM PF01423.22 KII83919.1 - 2.7e-09 36.6 0.0 3.4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII83919.1 - 0.00021 21.4 0.0 0.00027 21.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain RCDG1 PF15725.5 KII83919.1 - 0.91 10.0 5.0 0.88 10.0 3.6 1.7 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein ArAE_2 PF10334.9 KII83920.1 - 4.3e-57 193.6 0.1 7.5e-57 192.8 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KII83920.1 - 8e-44 150.4 24.3 2.6e-37 129.0 16.9 4.0 3 1 0 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KII83920.1 - 1.7e-10 41.1 9.7 1.7e-10 41.1 9.7 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like UPF0139 PF03669.13 KII83920.1 - 0.71 9.8 4.6 1.1 9.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) ADH_zinc_N PF00107.26 KII83921.1 - 2.7e-28 98.5 0.2 4.8e-28 97.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII83921.1 - 1.5e-20 74.6 0.1 5.3e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII83921.1 - 6.8e-11 42.0 0.0 1.6e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KII83921.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ELFV_dehydrog PF00208.21 KII83921.1 - 0.02 14.6 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 KII83921.1 - 0.044 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldolase_II PF00596.21 KII83922.1 - 1.9e-44 151.8 0.2 2.5e-44 151.4 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PTCB-BRCT PF12738.7 KII83923.1 - 5.1e-27 93.6 9.3 8e-18 64.1 0.2 4.5 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 KII83923.1 - 6.3e-22 77.8 0.1 6.6e-07 29.6 0.0 5.8 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KII83923.1 - 8.5e-17 61.3 0.0 0.00016 22.0 0.0 4.9 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KII83923.1 - 8.7e-16 57.6 0.1 6.3e-14 51.7 0.0 2.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KII83923.1 - 2e-09 37.6 1.1 0.0092 16.3 0.0 5.4 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KII83923.1 - 0.0028 17.7 2.1 3 8.0 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RabGAP-TBC PF00566.18 KII83924.1 - 9.4e-31 107.1 0.0 1.4e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Baculo_Y142 PF04913.12 KII83924.1 - 0.13 11.0 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein SH3_2 PF07653.17 KII83925.1 - 5.1e-06 26.1 0.0 7.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII83925.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Epimerase PF01370.21 KII83927.1 - 1.3e-18 67.4 0.1 2e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII83927.1 - 2.6e-11 43.5 0.2 1.7e-10 40.9 0.2 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII83927.1 - 9.1e-10 38.1 3.9 1.8e-08 33.9 3.9 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KII83927.1 - 9e-08 32.2 1.8 1.4e-07 31.6 1.8 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII83927.1 - 2.3e-07 30.1 0.1 3.4e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KII83927.1 - 1.1e-05 25.2 0.6 3.3e-05 23.6 1.1 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII83927.1 - 5.6e-05 22.4 0.2 9.2e-05 21.7 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KII83927.1 - 0.019 14.4 1.9 0.052 13.0 0.1 2.3 2 1 1 3 3 3 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KII83927.1 - 0.038 13.1 0.2 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 KII83927.1 - 0.04 13.8 4.2 0.19 11.6 4.2 1.9 1 1 0 1 1 1 0 KR domain ECH_1 PF00378.20 KII83928.1 - 5.6e-36 124.1 0.0 7.8e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII83928.1 - 1.1e-19 71.2 0.0 9.6e-16 58.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 KII83929.1 - 2.5e-184 613.1 0.0 2.9e-184 612.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KII83929.1 - 0.0044 16.5 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Mem_trans PF03547.18 KII83930.1 - 4.5e-19 68.1 0.0 7.7e-19 67.3 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein EP400_N PF15790.5 KII83931.1 - 0.096 11.5 4.8 0.14 11.0 4.8 1.3 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal TAF PF02969.17 KII83931.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Putative_PNPOx PF01243.20 KII83932.1 - 1.4e-06 28.4 0.1 0.0037 17.4 0.0 3.1 3 1 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 KII83932.1 - 0.0056 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF485 PF04341.12 KII83933.1 - 7.3 6.6 8.5 7 6.7 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 GST_N_3 PF13417.6 KII83934.1 - 2.1e-08 34.5 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII83934.1 - 7.6e-08 32.3 0.1 1.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII83934.1 - 9.4e-07 29.0 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII83934.1 - 4.2e-06 26.9 0.0 9.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 KII83934.1 - 0.00029 20.7 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.6 KII83934.1 - 0.00055 20.2 0.0 0.0015 18.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII83934.1 - 0.0048 17.2 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KII83934.1 - 0.11 12.3 0.0 0.91 9.4 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3341 PF11821.8 KII83935.1 - 0.17 11.5 2.1 0.17 11.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Gpr1_Fun34_YaaH PF01184.19 KII83936.1 - 3.3e-73 245.7 13.9 3.8e-73 245.5 13.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PTR2 PF00854.21 KII83937.1 - 1e-56 192.5 3.4 2.6e-56 191.2 3.4 1.5 1 1 0 1 1 1 1 POT family Fasciclin PF02469.22 KII83938.1 - 3.5e-35 121.0 1.3 3.7e-22 78.9 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain NmrA PF05368.13 KII83940.1 - 4.9e-28 98.3 0.0 6.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII83940.1 - 6e-11 42.6 0.0 8.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII83940.1 - 0.0015 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KII83940.1 - 0.085 13.3 0.1 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.14 KII83942.1 - 8.7e-55 185.8 0.0 1.2e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.18 KII83943.1 - 7.7e-08 32.3 9.8 1.2e-07 31.7 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4592 PF15262.6 KII83945.1 - 0.022 15.5 0.7 0.028 15.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) GMC_oxred_N PF00732.19 KII83946.1 - 5.6e-47 160.5 0.1 7.4e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII83946.1 - 5.3e-32 111.3 0.0 8.7e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII83946.1 - 2.1e-05 23.8 0.2 4.3e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII83946.1 - 8.1e-05 22.0 0.0 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII83946.1 - 0.00018 21.7 0.1 0.00049 20.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII83946.1 - 0.0006 19.0 0.2 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KII83946.1 - 0.0041 16.8 4.1 0.0048 16.5 2.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Catalase_C PF18011.1 KII83946.1 - 0.038 13.6 0.3 0.084 12.5 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases NAD_binding_9 PF13454.6 KII83946.1 - 0.072 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KII83946.1 - 0.092 11.4 0.2 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KII83946.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 KII83946.1 - 0.16 12.3 0.2 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Hydrolase PF00702.26 KII83947.1 - 3.3e-10 40.6 0.0 1.6e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KII83947.1 - 4.2e-08 33.5 0.0 9.6e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII83947.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like p450 PF00067.22 KII83948.1 - 3.3e-54 184.4 0.0 4.8e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.21 KII83949.1 - 5.9e-60 203.2 5.8 1e-59 202.4 5.8 1.3 1 0 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 KII83949.1 - 0.012 15.7 0.2 0.012 15.7 0.2 4.2 4 1 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_hydro_31 PF01055.26 KII83953.1 - 9.7e-132 440.3 0.0 1.4e-118 396.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KII83953.1 - 2.3e-29 102.0 0.0 5.4e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KII83953.1 - 7.4e-07 29.4 0.0 2.1e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Plavaka PF18759.1 KII83957.1 - 3.2e-36 125.2 0.0 6.1e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KII83957.1 - 0.12 12.8 0.7 0.43 11.1 0.7 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type adh_short_C2 PF13561.6 KII83958.1 - 5.9e-47 160.2 3.6 7.3e-47 159.9 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII83958.1 - 6e-34 117.2 1.7 7.4e-34 116.9 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII83958.1 - 1.2e-08 35.1 0.3 1.8e-08 34.5 0.3 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 KII83958.1 - 0.0048 16.4 0.2 0.0082 15.6 0.2 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Sacchrp_dh_NADP PF03435.18 KII83958.1 - 0.023 14.9 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L5 PF00281.19 KII83958.1 - 0.064 13.6 0.6 0.22 11.9 0.2 2.0 1 1 1 2 2 2 0 Ribosomal protein L5 HMG_box PF00505.19 KII83959.1 - 1.1e-16 60.9 0.8 1.9e-16 60.2 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII83959.1 - 1.8e-13 50.9 0.3 3.4e-13 50.0 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain PNP_UDP_1 PF01048.20 KII83960.1 - 3.1e-26 92.1 0.0 4e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily F-box-like PF12937.7 KII83961.1 - 8.9e-06 25.5 1.6 2.2e-05 24.2 1.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KII83961.1 - 0.24 11.2 0.0 0.24 11.2 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat Epimerase PF01370.21 KII83962.1 - 1.2e-19 70.8 0.0 1.7e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII83962.1 - 1.4e-11 44.1 0.5 1.8e-09 37.2 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KII83962.1 - 2.5e-10 39.9 0.0 3.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII83962.1 - 2.6e-10 40.5 0.2 7e-10 39.1 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII83962.1 - 3.8e-10 39.7 0.1 1.3e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KII83962.1 - 4.8e-08 32.8 0.0 1.7e-06 27.8 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII83962.1 - 1.7e-05 24.1 0.0 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KII83962.1 - 0.0071 16.3 1.5 0.081 12.8 1.5 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KII83962.1 - 0.0096 15.0 0.2 0.099 11.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 KII83962.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 KII83962.1 - 0.047 14.3 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_31 PF01055.26 KII83963.1 - 3.8e-146 487.7 2.4 5e-146 487.3 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KII83963.1 - 3.6e-30 104.5 0.0 7.2e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KII83963.1 - 8.5e-06 26.0 0.0 2.9e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_transf_90 PF05686.12 KII83965.1 - 1.6e-18 66.8 0.9 4.9e-16 58.6 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 Glyco_hydro_28 PF00295.17 KII83966.1 - 7.8e-42 143.5 7.5 1e-41 143.1 7.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SusD-like_2 PF12771.7 KII83966.1 - 0.15 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane p450 PF00067.22 KII83967.1 - 1.2e-46 159.4 0.0 1.5e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 KII83968.1 - 2.4e-13 49.9 0.0 1.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain p450 PF00067.22 KII83969.1 - 7.7e-45 153.5 0.0 1e-44 153.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII83970.1 - 4.8e-49 167.3 0.0 6.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.19 KII83970.1 - 0.036 13.9 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain DUF3602 PF12223.8 KII83971.1 - 7.1e-14 52.2 14.5 0.00022 21.8 1.2 3.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) APG12 PF04110.13 KII83972.1 - 4.6e-31 107.1 0.1 6e-31 106.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KII83972.1 - 0.0042 17.3 0.0 0.005 17.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Phage_holin_3_6 PF07332.11 KII83973.1 - 1 9.4 7.8 0.48 10.5 0.8 2.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III TBPIP PF07106.13 KII83974.1 - 4.4e-16 58.6 0.1 7.1e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF2540 PF10802.8 KII83974.1 - 0.016 15.3 0.2 0.06 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Tyr-DNA_phospho PF06087.12 KII83975.1 - 1.2e-54 185.8 0.0 2.3e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KII83975.1 - 8.4e-05 22.2 3.2 8.4e-05 22.2 3.2 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif PLDc_2 PF13091.6 KII83975.1 - 0.022 14.7 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain DUF4611 PF15387.6 KII83975.1 - 2 8.7 8.4 2.3 8.5 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4551 PF15087.6 KII83975.1 - 3.5 6.3 5.5 5 5.8 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.12 KII83975.1 - 3.7 7.3 5.3 61 3.3 5.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SWIRM-assoc_2 PF16496.5 KII83975.1 - 5.8 5.7 8.7 82 1.9 8.9 2.0 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal FAM176 PF14851.6 KII83975.1 - 6.9 6.3 6.9 26 4.5 4.4 2.3 2 0 0 2 2 2 0 FAM176 family TrbC PF04956.13 KII83977.1 - 0.075 13.3 0.1 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family SSFA2_C PF14723.6 KII83977.1 - 0.088 12.7 0.3 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Bacteriocin_IIc PF10439.9 KII83977.1 - 1 9.5 4.6 2.3 8.4 4.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Phage_holin_3_6 PF07332.11 KII83978.1 - 0.045 13.8 5.7 0.083 12.9 0.0 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Phage_holin_8 PF16931.5 KII83981.1 - 2.1 8.3 8.7 1.2 9.1 2.9 2.7 1 1 2 3 3 3 0 Putative phage holin Pkinase PF00069.25 KII83984.1 - 6.6e-66 222.4 0.0 2.1e-64 217.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII83984.1 - 1.4e-32 113.0 0.0 1.1e-29 103.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KII83984.1 - 3.8e-06 26.4 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII83984.1 - 6.1e-05 22.0 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII83984.1 - 8.1e-05 22.7 0.1 0.00025 21.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII83984.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KII83984.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WRNPLPNID PF15017.6 KII83984.1 - 9.8 7.1 11.6 2.8 8.9 3.6 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box PBP1_TM PF14812.6 KII83984.1 - 10 6.6 9.3 1 9.8 4.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dabb PF07876.12 KII83985.1 - 2.9e-15 56.7 0.0 3.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.16 KII83985.1 - 0.025 14.7 0.0 0.1 12.7 0.0 2.0 1 1 1 2 2 2 0 Antibiotic biosynthesis monooxygenase AcylCoA_dehyd_C PF12186.8 KII83986.1 - 0.06 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal DUF4916 PF16262.5 KII83991.1 - 0.097 12.2 0.0 2.3 7.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4916) BTB PF00651.31 KII83993.1 - 6.2e-10 39.3 0.1 1.6e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain MIG-14_Wnt-bd PF06664.12 KII83994.1 - 0.017 14.3 6.1 0.022 14.0 6.1 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF5400 PF17379.2 KII83996.1 - 1.6 9.3 10.0 0.058 13.9 2.0 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5400) HGTP_anticodon PF03129.20 KII83997.1 - 2.5e-21 75.6 0.0 5.1e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KII83997.1 - 4.1e-09 36.6 0.0 1.5e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SasG_E PF17041.5 KII83997.1 - 0.043 13.8 0.2 0.24 11.4 0.0 2.3 3 0 0 3 3 3 0 E domain NCE101 PF11654.8 KII84002.1 - 0.034 13.8 6.8 0.27 11.0 0.1 3.5 4 0 0 4 4 4 0 Non-classical export protein 1 BTB PF00651.31 KII84003.1 - 1.1e-09 38.5 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RACo_linker PF17650.1 KII84003.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RACo linker region BsuBI_PstI_RE_N PF17728.1 KII84004.1 - 0.086 12.7 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain Collagen PF01391.18 KII84005.1 - 0.03 14.1 5.5 0.03 14.1 5.5 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) MPS2 PF17060.5 KII84006.1 - 0.0015 17.9 7.4 0.0053 16.1 7.4 1.8 1 1 0 1 1 1 1 Monopolar spindle protein 2 DUF16 PF01519.16 KII84006.1 - 0.0051 17.3 15.6 0.16 12.5 4.0 2.9 1 1 2 3 3 3 3 Protein of unknown function DUF16 Atg14 PF10186.9 KII84006.1 - 0.061 12.4 8.7 0.11 11.6 8.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KII84006.1 - 0.083 12.4 11.1 0.21 11.1 11.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit ZnuA PF01297.17 KII84006.1 - 0.13 11.7 8.7 0.087 12.2 2.5 2.1 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic ERM PF00769.19 KII84006.1 - 0.37 10.6 16.4 0.76 9.5 16.4 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMF_TATA_bd PF12325.8 KII84006.1 - 1.3 9.2 12.7 2.6 8.3 5.2 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KII84006.1 - 5.7 5.7 14.1 2.1 7.2 8.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Flagellin_C PF00700.21 KII84006.1 - 7 7.1 10.9 6.2 7.3 2.1 3.4 2 1 2 4 4 4 0 Bacterial flagellin C-terminal helical region Sec2p PF06428.11 KII84006.1 - 7 6.7 8.4 26 4.9 0.1 3.1 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p BTB PF00651.31 KII84008.1 - 4.8e-11 42.9 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII84009.1 - 5.5e-08 33.0 0.0 1.3e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KII84010.1 - 1.6e-10 41.2 0.0 3.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII84011.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Bestrophin PF01062.21 KII84012.1 - 8.2e-35 120.6 3.1 7.8e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF1129 PF06570.11 KII84012.1 - 0.22 11.0 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FMO-like PF00743.19 KII84013.1 - 1.3e-22 80.0 0.0 5.7e-12 44.8 0.0 4.0 4 0 0 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KII84013.1 - 1.8e-10 40.6 0.0 3.2e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII84013.1 - 4.7e-10 39.2 0.3 7.4e-05 22.1 0.0 2.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII84013.1 - 1.5e-07 31.5 0.4 3.5e-06 27.1 0.0 3.1 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII84013.1 - 7.5e-05 22.1 0.2 0.0053 16.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KII84013.1 - 0.00033 19.9 0.1 0.03 13.5 0.0 3.0 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KII84013.1 - 0.00038 19.8 0.2 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII84013.1 - 0.00098 17.9 0.3 0.0021 16.8 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KII84013.1 - 0.001 18.7 0.9 0.038 13.6 0.3 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII84013.1 - 0.0016 18.5 0.4 0.11 12.5 0.0 3.3 2 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KII84013.1 - 0.0017 18.4 0.1 0.4 10.7 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KII84013.1 - 0.0041 17.5 0.2 0.19 12.2 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 KII84013.1 - 0.006 15.9 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KII84013.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KII84013.1 - 0.015 14.6 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KII84013.1 - 0.023 14.1 0.1 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KII84013.1 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KII84013.1 - 0.037 14.6 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TraF PF13728.6 KII84013.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Glu_dehyd_C PF16912.5 KII84013.1 - 0.064 12.7 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 KII84013.1 - 0.066 13.1 0.2 0.66 9.8 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KII84013.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Rhodanese PF00581.20 KII84014.1 - 9e-19 68.0 0.0 2.1e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SSF PF00474.17 KII84015.1 - 2.1e-19 69.7 32.4 2.1e-19 69.7 32.4 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family zf-C2H2 PF00096.26 KII84016.1 - 0.047 14.2 3.6 0.11 13.1 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII84016.1 - 1.8 9.6 3.7 4.2 8.5 3.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger BTB PF00651.31 KII84017.1 - 5.5e-10 39.5 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain EBP PF05241.12 KII84018.1 - 8.6e-05 22.1 12.7 0.00038 20.0 12.7 1.9 1 1 0 1 1 1 1 Emopamil binding protein Pyr_redox_3 PF13738.6 KII84019.1 - 2.4e-19 69.7 0.0 1.7e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KII84019.1 - 3.6e-18 65.3 0.0 1.2e-17 63.6 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KII84019.1 - 4.5e-16 58.9 0.1 1.8e-05 24.1 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII84019.1 - 1.1e-11 44.5 0.1 8.6e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KII84019.1 - 6.3e-06 26.7 0.1 0.067 13.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KII84019.1 - 1.3e-05 25.3 0.1 0.0037 17.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KII84019.1 - 0.00029 20.9 0.4 1.1 9.2 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 KII84019.1 - 0.0018 18.5 0.0 0.082 13.2 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain SnoaL_4 PF13577.6 KII84019.1 - 0.005 17.0 0.1 0.068 13.3 0.1 2.7 2 1 0 2 2 2 1 SnoaL-like domain NAD_binding_7 PF13241.6 KII84019.1 - 0.0071 16.8 0.0 1.4 9.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 KII84019.1 - 0.013 15.1 2.5 0.52 9.8 0.3 3.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase SnoaL_2 PF12680.7 KII84019.1 - 0.02 15.5 0.6 0.069 13.8 0.3 2.1 2 0 0 2 2 2 0 SnoaL-like domain Lycopene_cycl PF05834.12 KII84019.1 - 0.034 13.2 0.0 5.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KII84019.1 - 0.047 13.0 0.1 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SnoaL_3 PF13474.6 KII84019.1 - 0.16 12.3 0.4 1 9.6 0.1 2.5 3 0 0 3 3 3 0 SnoaL-like domain SSF PF00474.17 KII84020.1 - 7.4e-18 64.6 35.3 7.4e-18 64.6 35.3 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF4713 PF15831.5 KII84020.1 - 1.4 9.4 4.7 1.5 9.3 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4713) BTB PF00651.31 KII84021.1 - 4.6e-07 30.1 0.1 8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain FMO-like PF00743.19 KII84022.1 - 4.4e-18 65.0 0.0 2.7e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII84022.1 - 6.8e-18 65.0 0.0 7e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII84022.1 - 1.6e-14 53.9 0.0 1.6e-06 27.6 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII84022.1 - 1.9e-11 43.7 0.0 2.4e-09 36.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KII84022.1 - 5.1e-06 26.9 0.0 0.033 14.7 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KII84022.1 - 2.2e-05 24.6 0.0 0.00036 20.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KII84022.1 - 8.2e-05 22.9 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_8 PF13450.6 KII84022.1 - 0.0012 19.0 0.0 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KII84022.1 - 0.049 13.0 0.0 0.64 9.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KII84022.1 - 0.08 11.6 0.0 0.24 10.1 0.0 1.8 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 KII84022.1 - 0.08 13.4 0.0 0.69 10.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HARP PF07443.13 KII84022.1 - 0.21 11.3 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) F-box PF00646.33 KII84026.1 - 1.7e-06 27.8 0.3 8e-06 25.6 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII84026.1 - 0.0018 18.1 0.3 0.011 15.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KII84026.1 - 0.076 12.9 0.4 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 F-box Zn_Tnp_IS91 PF14319.6 KII84026.1 - 3.2 7.8 8.1 6.2 6.9 0.9 3.1 3 0 0 3 3 3 0 Transposase zinc-binding domain ParBc PF02195.18 KII84027.1 - 0.12 12.7 0.1 0.35 11.2 0.0 1.9 3 0 0 3 3 3 0 ParB-like nuclease domain SUR7 PF06687.12 KII84029.1 - 6e-15 55.5 16.8 1.6e-14 54.0 15.6 2.1 1 1 1 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.6 KII84029.1 - 0.0023 17.7 2.4 0.0089 15.8 2.4 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.10 KII84029.1 - 0.012 15.4 0.2 0.017 14.9 0.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tad PF13400.6 KII84029.1 - 0.16 12.3 0.3 0.16 12.3 0.3 3.1 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like DuoxA PF10204.9 KII84029.1 - 0.43 9.5 4.4 0.72 8.8 4.4 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor RseC_MucC PF04246.12 KII84029.1 - 1.1 9.3 3.5 1.6 8.7 0.0 2.3 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF983 PF06170.12 KII84029.1 - 5.1 7.6 7.1 18 5.8 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) FhuF_C PF11575.8 KII84030.1 - 4.5 7.3 6.5 3.9 7.5 0.2 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Glyco_hydro_30 PF02055.16 KII84031.1 - 2.4e-24 85.9 0.1 3.2e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KII84031.1 - 8.1e-15 54.8 0.1 1.2e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KII84031.1 - 1.7e-05 24.6 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Asp PF00026.23 KII84032.1 - 5.4e-52 177.2 16.9 7.2e-52 176.8 16.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII84032.1 - 3.5e-08 33.9 14.2 2e-05 24.9 0.4 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII84032.1 - 1.1e-05 26.0 6.5 0.0019 18.8 1.8 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KII84032.1 - 0.0093 16.5 4.7 0.3 11.7 0.4 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KII84032.1 - 0.03 14.1 0.2 1.6 8.5 0.2 2.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Sugarporin_N PF11471.8 KII84033.1 - 0.02 14.8 1.8 0.039 13.9 1.8 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Uds1 PF15456.6 KII84034.1 - 0.12 12.6 2.5 0.17 12.0 2.5 1.4 1 1 0 1 1 1 0 Up-regulated During Septation PSK_trans_fac PF07704.11 KII84034.1 - 0.58 11.0 5.3 2.3 9.0 5.0 2.1 1 1 0 1 1 1 0 Rv0623-like transcription factor DUF1192 PF06698.11 KII84034.1 - 0.77 9.9 5.5 0.35 10.9 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 KII84036.1 - 8.2e-05 22.4 0.3 0.00024 20.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KII84036.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 F-box LRR_6 PF13516.6 KII84036.1 - 0.21 11.7 3.1 9.7 6.5 0.5 3.7 3 0 0 3 3 3 0 Leucine Rich repeat COX8 PF02285.15 KII84037.1 - 0.14 12.1 0.1 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DIE2_ALG10 PF04922.12 KII84038.1 - 0.12 11.6 4.3 0.15 11.3 4.3 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family SSF PF00474.17 KII84039.1 - 3.2e-17 62.5 21.9 3.2e-17 62.5 21.9 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family Amidase PF01425.21 KII84040.1 - 1.8e-93 314.0 0.0 2.2e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Amidase SSF PF00474.17 KII84041.1 - 9.1e-24 84.1 25.7 1.5e-23 83.4 25.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family ArAE_2_N PF10337.9 KII84041.1 - 0.028 13.5 0.8 0.088 11.8 0.8 1.8 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal SPX PF03105.19 KII84042.1 - 0.13 12.1 6.0 0.17 11.7 6.0 1.1 1 0 0 1 1 1 0 SPX domain RrnaAD PF00398.20 KII84043.1 - 8.2e-58 195.6 0.0 1.1e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KII84043.1 - 8.1e-07 29.7 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84043.1 - 5e-05 23.9 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII84043.1 - 0.00031 20.6 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII84043.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KII84043.1 - 0.00086 20.0 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KII84043.1 - 0.00086 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KII84043.1 - 0.0026 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KII84043.1 - 0.0039 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KII84043.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KII84043.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Met_10 PF02475.16 KII84043.1 - 0.032 14.0 0.1 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Met-10+ like-protein Ubie_methyltran PF01209.18 KII84043.1 - 0.043 13.1 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KII84043.1 - 0.056 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cons_hypoth95 PF03602.15 KII84043.1 - 0.12 12.0 0.1 0.77 9.4 0.0 2.3 2 1 1 3 3 3 0 Conserved hypothetical protein 95 NodS PF05401.11 KII84043.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) SUI1 PF01253.22 KII84045.1 - 3.3e-17 62.8 0.0 5.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KII84045.1 - 6.2e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KII84045.1 - 6.3e-07 29.3 0.1 1.7e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 KII84045.1 - 0.0098 15.8 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.9 KII84045.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein DUF3915 PF13054.6 KII84045.1 - 0.14 12.1 1.5 0.25 11.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Kelch_4 PF13418.6 KII84047.1 - 1.4e-40 137.0 24.3 6.6e-09 35.6 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KII84047.1 - 2.1e-35 120.0 14.9 2e-08 33.7 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KII84047.1 - 2.2e-33 113.9 31.7 7.1e-08 32.6 0.1 7.6 8 1 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KII84047.1 - 2.6e-31 107.1 10.5 3.5e-08 33.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KII84047.1 - 4.5e-29 99.8 15.0 0.0001 22.5 0.0 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_2 PF07646.15 KII84047.1 - 2.3e-21 74.9 14.9 7.9e-06 25.7 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Abhydrolase_6 PF12697.7 KII84049.1 - 0.00016 22.4 0.2 0.0018 19.0 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII84049.1 - 0.1 11.8 0.0 23 4.1 0.0 3.2 3 1 0 3 3 3 0 Serine aminopeptidase, S33 TMEM132D_N PF15705.5 KII84049.1 - 0.23 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Transp_Tc5_C PF04236.15 KII84050.1 - 0.12 12.8 1.5 0.15 12.4 0.5 1.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain RMMBL PF07521.12 KII84054.1 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain KDZ PF18758.1 KII84055.1 - 2.2e-56 191.0 0.0 3.6e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII84055.1 - 2.5e-42 143.4 0.0 8.5e-42 141.7 0.2 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII84055.1 - 5.2e-05 23.3 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KII84055.1 - 0.0018 18.4 1.6 0.0055 16.8 1.6 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) CxC3 PF18804.1 KII84055.1 - 0.0061 16.4 0.1 0.017 14.9 0.1 1.8 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KII84055.1 - 0.35 11.1 7.1 0.064 13.4 3.0 2.0 2 0 0 2 2 2 0 B-box zinc finger 2OG-FeII_Oxy_3 PF13640.6 KII84058.1 - 0.0012 19.7 0.0 0.0019 19.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FGGY_C PF02782.16 KII84058.1 - 0.025 14.3 0.1 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Cauli_VI PF01693.16 KII84060.1 - 9.4e-08 32.2 0.8 1.3e-06 28.6 0.1 2.6 3 0 0 3 3 3 1 Caulimovirus viroplasmin PSCyt2 PF07583.11 KII84061.1 - 0.19 11.6 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) SurE PF01975.17 KII84065.1 - 1.6e-37 129.2 0.2 2.7e-37 128.4 0.2 1.3 1 0 0 1 1 1 1 Survival protein SurE Amino_oxidase PF01593.24 KII84066.1 - 1.9e-38 133.0 0.0 2.4e-27 96.3 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII84066.1 - 1.3e-05 25.3 0.0 4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KII84067.1 - 3.7e-30 105.6 0.1 6.1e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 KII84068.1 - 1.9e-20 73.0 0.0 3.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84068.1 - 9.9e-10 38.4 5.6 1.7e-09 37.7 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.17 KII84069.1 - 3.5e-38 131.3 0.3 4.8e-38 130.9 0.3 1.1 1 0 0 1 1 1 1 Survival protein SurE Peripla_BP_4 PF13407.6 KII84069.1 - 0.036 13.6 0.1 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain HMG_box PF00505.19 KII84070.1 - 1.5e-23 83.0 0.6 2.6e-23 82.2 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII84070.1 - 1.1e-18 67.6 1.1 1.1e-18 67.6 1.1 1.6 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 KII84070.1 - 0.00041 20.3 0.0 0.00098 19.0 0.0 1.6 1 1 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 KII84070.1 - 0.0051 17.4 1.2 0.0056 17.3 0.5 1.4 1 1 1 2 2 2 1 YABBY protein HMG_box_5 PF14887.6 KII84070.1 - 0.011 15.7 2.4 0.011 15.7 2.4 1.9 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Sigma_reg_N PF13800.6 KII84071.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Vpu PF00558.19 KII84071.1 - 5.1 6.9 7.2 0.45 10.3 0.6 2.5 2 1 1 3 3 3 0 Vpu protein EAP30 PF04157.16 KII84072.1 - 8.9e-72 241.2 0.3 1e-71 241.0 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.6 KII84072.1 - 0.011 15.5 0.2 0.035 13.8 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4423) TetR_C_15 PF17918.1 KII84072.1 - 1.4 9.8 6.6 2 9.2 0.4 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AA_permease PF00324.21 KII84073.1 - 5.4e-127 424.3 34.4 6.1e-127 424.1 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII84073.1 - 3.2e-34 118.5 39.9 4.3e-34 118.1 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.19 KII84074.1 - 2.6e-23 82.9 0.0 6.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KII84074.1 - 4.7e-05 23.5 0.4 0.00011 22.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII84074.1 - 0.0049 16.1 0.1 0.017 14.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII84074.1 - 0.0075 15.9 0.7 0.01 15.4 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KII84074.1 - 0.019 13.6 0.3 0.19 10.4 0.6 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KII84074.1 - 0.034 13.3 0.2 0.062 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KII84074.1 - 0.04 13.2 0.1 0.072 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KII84074.1 - 0.11 11.4 0.7 0.43 9.4 0.2 2.2 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.10 KII84074.1 - 0.13 11.3 0.0 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase F-box PF00646.33 KII84075.1 - 0.00083 19.2 0.1 0.0028 17.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain CpXC PF14353.6 KII84075.1 - 4.9 7.2 8.1 10 6.2 0.2 2.9 3 0 0 3 3 3 0 CpXC protein DUF3494 PF11999.8 KII84076.1 - 3.1e-58 196.9 21.7 3.1e-58 196.9 21.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3494) DUF2844 PF11005.8 KII84076.1 - 0.02 14.9 1.2 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2844) DPBB_1 PF03330.18 KII84077.1 - 6.5e-09 35.9 0.1 1.3e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase DPBB_1 PF03330.18 KII84079.1 - 1.7e-06 28.2 0.1 3e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase YABBY PF04690.13 KII84079.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 YABBY protein SNF2_N PF00176.23 KII84081.1 - 7e-36 123.6 0.0 9.8e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII84081.1 - 6.8e-21 74.7 0.0 3.4e-18 66.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KII84081.1 - 4.1e-05 22.9 0.0 9.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase VIGSSK PF14773.6 KII84081.1 - 0.018 15.2 2.0 0.024 14.8 0.0 2.3 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal SEC-C PF02810.15 KII84081.1 - 4.2 7.4 10.4 0.25 11.3 5.0 1.8 2 0 0 2 2 2 0 SEC-C motif Peptidase_C65 PF10275.9 KII84082.1 - 2.2e-62 210.7 0.0 2.6e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KII84082.1 - 0.00071 20.1 0.0 0.037 14.5 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease PseudoU_synth_1 PF01416.20 KII84083.1 - 1.5e-27 96.2 0.0 4.3e-26 91.5 0.0 2.8 2 1 0 2 2 2 1 tRNA pseudouridine synthase Peptidase_M28 PF04389.17 KII84088.1 - 2.5e-28 99.1 0.0 4.2e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KII84088.1 - 1.8e-05 24.5 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 p450 PF00067.22 KII84091.1 - 8.6e-69 232.5 0.0 1.8e-68 231.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Oxysterol_BP PF01237.18 KII84092.1 - 8.7e-59 199.2 0.3 2.8e-56 191.0 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein p450 PF00067.22 KII84093.1 - 7.5e-59 199.7 0.0 1.7e-58 198.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII84094.1 - 1e-58 199.2 0.0 2.6e-58 197.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KII84095.1 - 1.7e-06 27.8 0.0 5.4e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like Mem_trans PF03547.18 KII84097.1 - 1.6e-06 26.8 6.3 4.5e-06 25.3 5.2 2.4 1 1 0 1 1 1 1 Membrane transport protein Aminotran_1_2 PF00155.21 KII84100.1 - 8.9e-24 84.3 0.0 1.3e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3262 PF11660.8 KII84101.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) DPBB_1 PF03330.18 KII84103.1 - 0.0031 17.8 0.1 0.0042 17.3 0.1 1.4 1 1 0 1 1 1 1 Lytic transglycolase UQ_con PF00179.26 KII84104.1 - 3.8e-46 156.2 0.0 4.4e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KII84104.1 - 0.0018 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RNA_pol_Rpb2_6 PF00562.28 KII84105.1 - 4.4e-123 411.2 0.3 6.2e-123 410.7 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KII84105.1 - 1.4e-56 191.2 0.0 2.3e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KII84105.1 - 2e-32 111.4 0.3 5.4e-32 110.1 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KII84105.1 - 1.5e-29 103.0 0.1 3.5e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KII84105.1 - 5.2e-25 87.5 2.7 1.3e-24 86.3 1.5 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KII84105.1 - 5e-20 71.4 0.0 1.4e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KII84105.1 - 6.5e-11 42.6 1.0 2.1e-10 41.0 1.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.26 KII84106.1 - 6.1e-45 152.3 0.0 7e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KII84106.1 - 0.037 13.7 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B ALO PF04030.14 KII84107.1 - 1e-78 264.8 0.0 2.2e-78 263.7 0.0 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KII84107.1 - 1e-28 99.8 0.2 1.6e-28 99.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HSP70 PF00012.20 KII84108.1 - 0.00058 18.2 0.0 0.00096 17.5 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein DUF735 PF05246.11 KII84110.1 - 0.21 11.5 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Noc2 PF03715.13 KII84111.1 - 3.9e-119 397.3 0.5 5.4e-118 393.6 0.1 2.2 2 0 0 2 2 2 1 Noc2p family DUF1570 PF07607.11 KII84111.1 - 0.11 12.8 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) SGT1 PF07093.11 KII84111.1 - 9.7 4.5 10.1 14 4.0 10.1 1.2 1 0 0 1 1 1 0 SGT1 protein MT-A70 PF05063.14 KII84112.1 - 9.4e-39 133.1 0.0 1.8e-38 132.2 0.0 1.4 1 1 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 KII84112.1 - 0.22 11.3 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Got1 PF04178.12 KII84113.1 - 1.4e-32 112.4 11.3 1.8e-32 112.1 11.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 KII84113.1 - 0.0022 16.4 4.1 0.0026 16.1 4.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) AgrB PF04647.15 KII84113.1 - 0.047 13.0 5.9 0.063 12.6 5.9 1.1 1 0 0 1 1 1 0 Accessory gene regulator B Acyl_transf_3 PF01757.22 KII84113.1 - 0.15 11.1 14.4 0.19 10.7 14.4 1.1 1 0 0 1 1 1 0 Acyltransferase family TM_helix PF05552.12 KII84113.1 - 0.34 10.9 2.9 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Conserved TM helix EcsB PF05975.12 KII84113.1 - 0.44 9.4 7.2 0.58 8.9 7.2 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB MNHE PF01899.16 KII84113.1 - 8.6 6.1 8.7 48 3.7 8.7 1.9 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit Nup192 PF11894.8 KII84114.1 - 6.1e-251 835.9 0.0 8.1e-251 835.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 STAS_2 PF13466.6 KII84114.1 - 0.22 11.9 1.8 1.2 9.5 1.8 2.3 1 0 0 1 1 1 0 STAS domain Hexapep PF00132.24 KII84115.1 - 6.3e-08 32.0 16.2 0.0031 17.2 0.2 4.1 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KII84115.1 - 0.38 10.5 14.5 0.083 12.7 5.6 2.9 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CMD PF02627.20 KII84116.1 - 0.023 14.7 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Metallophos PF00149.28 KII84117.1 - 3.7e-13 50.4 0.5 6.8e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII84117.1 - 1.8e-07 31.5 0.5 3.3e-06 27.4 0.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mem_trans PF03547.18 KII84118.1 - 6.8e-14 51.1 12.9 3.9e-07 28.8 8.4 2.3 2 0 0 2 2 2 2 Membrane transport protein Abhydrolase_1 PF00561.20 KII84119.1 - 1e-18 68.0 0.1 5.7e-18 65.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII84119.1 - 8.6e-12 46.1 1.4 1.1e-11 45.8 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII84119.1 - 1.3e-09 37.6 0.2 4e-09 36.1 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KII84119.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Topoisom_I_N PF02919.15 KII84119.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PGAP1 PF07819.13 KII84119.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Linocin_M18 PF04454.12 KII84120.1 - 0.096 12.0 0.4 0.15 11.4 0.4 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase GreA_GreB_N PF03449.15 KII84120.1 - 0.69 10.1 5.6 32 4.8 1.2 3.2 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal EI24 PF07264.11 KII84121.1 - 5e-14 52.9 5.4 7.1e-14 52.4 5.4 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3325 PF11804.8 KII84121.1 - 0.025 14.7 1.2 0.025 14.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) AAA_30 PF13604.6 KII84122.1 - 8.5e-14 51.7 0.0 2.8e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII84122.1 - 4.8e-13 49.5 0.0 1.4e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KII84122.1 - 2.5e-10 40.3 0.0 6.6e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII84122.1 - 3.7e-08 33.8 0.0 1.1e-07 32.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII84122.1 - 8.7e-05 23.0 0.0 0.00025 21.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KII84122.1 - 0.0011 19.4 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KII84122.1 - 0.0056 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 KII84122.1 - 0.01 15.7 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_33 PF13671.6 KII84122.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KII84122.1 - 0.047 14.0 0.1 0.27 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KII84122.1 - 0.048 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KII84122.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 KII84122.1 - 0.078 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase SRP54 PF00448.22 KII84122.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 KII84122.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_7 PF12775.7 KII84122.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region tRNA-synt_1 PF00133.22 KII84124.1 - 4.4e-32 111.1 0.3 1.5e-13 49.9 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KII84124.1 - 1e-15 57.4 0.0 1.2e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KII84124.1 - 4.5e-14 52.7 0.0 9.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KII84124.1 - 1.2e-07 31.4 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain BEN PF10523.9 KII84124.1 - 0.014 15.6 0.0 0.063 13.5 0.0 2.1 2 0 0 2 2 2 0 BEN domain Peptidase_M50 PF02163.22 KII84125.1 - 4.7e-10 39.2 0.0 3.6e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M50 PDZ PF00595.24 KII84125.1 - 0.039 14.3 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 KII84125.1 - 0.093 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain NUFIP2 PF15293.6 KII84125.1 - 0.55 9.1 0.7 0.74 8.6 0.7 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 PhaP_Bmeg PF09602.10 KII84127.1 - 0.021 14.8 0.5 0.047 13.6 0.1 1.6 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) YyzF PF14116.6 KII84127.1 - 0.64 10.1 4.0 41 4.3 0.2 3.9 3 0 0 3 3 3 0 YyzF-like protein MFS_1 PF07690.16 KII84128.1 - 1.9e-25 89.6 52.1 1.9e-25 89.6 52.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII84128.1 - 3.6e-11 42.2 18.5 7e-11 41.3 18.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KII84128.1 - 5.1e-06 25.6 30.4 1.4e-05 24.2 9.7 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.22 KII84130.1 - 4.9e-34 117.9 0.0 1.6e-33 116.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KII84131.1 - 1.4e-61 208.5 0.0 2e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII84131.1 - 1.6e-34 119.5 0.2 5.1e-34 117.8 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 KII84131.1 - 1.2e-06 28.3 0.0 3.6e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII84131.1 - 7.8e-05 22.8 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KII84131.1 - 0.00059 19.0 0.0 0.00086 18.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII84131.1 - 0.00077 18.8 0.0 0.0022 17.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII84131.1 - 0.0018 17.4 0.2 0.0063 15.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KII84131.1 - 0.14 12.7 0.2 0.31 11.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII84131.1 - 0.19 10.4 0.1 0.32 9.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 KII84133.1 - 5.1e-29 101.3 54.2 5.1e-29 101.3 54.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII84133.1 - 1.7e-12 46.6 19.2 2.7e-12 45.9 19.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) S1FA PF04689.13 KII84133.1 - 0.26 11.5 3.9 2.2 8.5 0.2 3.1 2 0 0 2 2 2 0 DNA binding protein S1FA Acetyltransf_1 PF00583.25 KII84134.1 - 5.4e-14 52.4 0.0 8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII84134.1 - 7.2e-09 35.7 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII84134.1 - 2.9e-08 34.0 0.0 4.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII84134.1 - 5e-07 29.6 0.1 8.1e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KII84134.1 - 0.00013 22.7 0.0 0.00016 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII84134.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII84134.1 - 0.0094 15.6 0.6 0.012 15.3 0.0 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KII84134.1 - 0.023 14.4 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ HSP70 PF00012.20 KII84135.1 - 2.5e-262 871.4 7.3 2.8e-262 871.3 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KII84135.1 - 4.2e-18 65.2 1.7 2.2e-17 62.9 0.5 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 KII84135.1 - 0.0005 19.1 0.8 0.034 13.1 0.3 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KII84135.1 - 0.043 13.1 0.2 0.13 11.4 0.2 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase AA_permease_2 PF13520.6 KII84137.1 - 3.7e-64 217.1 55.2 4.6e-64 216.8 55.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII84137.1 - 2.8e-14 52.6 51.7 6.8e-14 51.3 51.7 1.5 1 1 0 1 1 1 1 Amino acid permease COX7B PF05392.11 KII84137.1 - 0.029 14.1 0.1 0.075 12.7 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Mem_trans PF03547.18 KII84138.1 - 3.4e-22 78.4 14.2 2.9e-12 45.7 5.6 2.1 2 0 0 2 2 2 2 Membrane transport protein STE3 PF02076.15 KII84139.1 - 1.8e-64 217.8 22.2 2e-64 217.6 22.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Ead_Ea22 PF13935.6 KII84140.1 - 0.019 15.6 1.6 0.047 14.4 1.6 1.6 1 0 0 1 1 1 0 Ead/Ea22-like protein Methyltransf_2 PF00891.18 KII84142.1 - 2.5e-23 82.5 0.0 1e-21 77.2 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII84142.1 - 0.002 17.9 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII84142.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KII84142.1 - 0.02 15.6 0.0 0.067 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain STE3 PF02076.15 KII84143.1 - 1.6e-115 385.3 18.0 2e-115 385.0 18.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor SNF2_N PF00176.23 KII84144.1 - 6.2e-44 150.1 0.0 1.1e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 KII84144.1 - 2.7e-06 27.2 9.8 5e-06 26.3 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII84144.1 - 1.8e-05 24.5 12.3 3.1e-05 23.8 12.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII84144.1 - 6.3e-05 23.2 14.6 0.00012 22.3 14.6 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII84144.1 - 8e-05 22.4 8.5 0.00014 21.6 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.31 KII84144.1 - 0.00026 21.3 0.0 0.00088 19.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KII84144.1 - 0.00065 19.6 12.9 0.0013 18.7 12.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII84144.1 - 0.00099 18.9 13.8 0.0019 18.0 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KII84144.1 - 0.0029 17.8 7.5 0.0068 16.7 7.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII84144.1 - 0.38 10.8 6.3 1.2 9.3 6.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KII84144.1 - 1.1 9.5 10.4 2.3 8.5 10.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KII84144.1 - 1.5 8.5 10.9 3.2 7.4 10.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KII84144.1 - 1.6 8.8 9.2 4.1 7.5 9.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Myb_DNA-binding PF00249.31 KII84145.1 - 5.4e-19 68.1 0.2 1.7e-10 40.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII84145.1 - 6.9e-14 51.8 0.1 1.7e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KII84145.1 - 0.0017 18.4 0.2 0.32 11.0 0.1 2.3 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 KII84145.1 - 0.28 11.4 0.5 0.64 10.3 0.1 1.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 PCI PF01399.27 KII84146.1 - 7e-09 36.1 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain DUF3562 PF12085.8 KII84146.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Glyco_hydro_79C PF16862.5 KII84147.1 - 6.9e-20 71.9 0.1 2.4e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain zf-MYND PF01753.18 KII84148.1 - 0.0019 18.2 10.9 0.007 16.4 10.9 2.0 1 1 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KII84148.1 - 0.013 15.3 4.0 0.013 15.3 4.0 2.5 3 0 0 3 3 3 0 HIT zinc finger AA_permease_2 PF13520.6 KII84149.1 - 3.6e-46 157.9 47.2 2.8e-24 85.8 15.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KII84149.1 - 3.9e-17 62.0 40.7 1.3e-11 43.8 19.4 2.2 2 0 0 2 2 2 2 Amino acid permease DAD PF02109.16 KII84149.1 - 3.3 8.1 7.0 1.6 9.1 1.0 2.7 2 0 0 2 2 2 0 DAD family LPAM_2 PF13627.6 KII84151.1 - 1.7 8.6 5.3 7.1 6.6 5.3 2.2 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site SelP_N PF04592.14 KII84152.1 - 2.7 7.3 16.9 3.5 6.9 16.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 KII84153.1 - 7.1e-37 127.1 30.6 7.1e-37 127.1 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII84153.1 - 2.8e-09 36.4 17.7 1.2e-08 34.3 18.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KII84153.1 - 0.00075 18.0 8.0 0.0008 17.9 7.1 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector UbiA PF01040.18 KII84154.1 - 1.8e-18 66.8 4.4 2.1e-18 66.6 4.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PhoR PF11808.8 KII84154.1 - 0.059 13.8 0.5 0.059 13.8 0.5 2.3 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR zf-MYND PF01753.18 KII84155.1 - 4.3e-11 42.7 18.8 4.3e-11 42.7 18.8 2.6 3 0 0 3 3 3 1 MYND finger PolC_DP2 PF03833.13 KII84155.1 - 1.6 6.5 4.9 2.4 5.9 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Peptidase_S9 PF00326.21 KII84157.1 - 3.3e-31 108.4 0.0 4.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KII84157.1 - 0.00015 21.1 0.3 0.0068 15.7 0.2 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII84157.1 - 0.00027 20.7 0.2 0.0075 15.9 0.5 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KII84157.1 - 0.024 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KII84157.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DLH PF01738.18 KII84157.1 - 0.2 11.2 0.0 0.55 9.8 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family La PF05383.17 KII84158.1 - 3.8e-22 78.1 0.0 1.3e-21 76.4 0.0 1.8 2 0 0 2 2 2 1 La domain RRM_3 PF08777.11 KII84158.1 - 0.00014 21.9 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 KII84158.1 - 0.00038 20.2 0.3 0.00094 19.0 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3564 PF12087.8 KII84159.1 - 0.062 13.2 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) ATP_synt_H PF05493.13 KII84160.1 - 1.2 9.7 19.0 11 6.6 0.6 3.3 3 0 0 3 3 3 0 ATP synthase subunit H p450 PF00067.22 KII84162.1 - 9.8e-69 232.3 0.0 1.1e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 KII84163.1 - 6.4e-26 91.5 0.1 9.8e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII84163.1 - 4.6e-11 42.2 0.0 1.1e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase ADH_zinc_N PF00107.26 KII84164.1 - 2.4e-24 85.7 0.1 5.2e-24 84.7 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII84164.1 - 9.5e-13 49.4 0.0 2.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII84164.1 - 5.8e-10 39.0 0.1 3.2e-08 33.4 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Haem_degrading PF03928.14 KII84164.1 - 0.05 13.7 0.1 0.1 12.6 0.1 1.5 1 1 0 1 1 1 0 Haem-degrading HupF_HypC PF01455.18 KII84164.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 HupF/HypC family Glyco_hydro_61 PF03443.14 KII84165.1 - 5e-61 206.2 0.0 5.9e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KII84166.1 - 1.6e-44 152.3 21.6 2.9e-44 151.4 21.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII84166.1 - 1.3e-06 27.6 4.8 1.3e-06 27.6 4.8 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4564 PF15169.6 KII84166.1 - 0.24 11.1 0.2 0.42 10.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Oxidored_q2 PF00420.24 KII84166.1 - 0.47 10.1 4.5 0.54 9.9 0.9 2.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Gln-synt_C PF00120.24 KII84167.1 - 0.021 13.8 0.4 0.028 13.4 0.4 1.1 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain KASH_CCD PF14662.6 KII84167.1 - 0.13 12.1 2.3 0.17 11.7 2.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BCS1_N PF08740.11 KII84168.1 - 1.3e-21 77.4 7.5 6.7e-14 52.3 1.4 2.6 2 1 1 3 3 3 2 BCS1 N terminal AAA PF00004.29 KII84168.1 - 3e-19 69.8 0.0 1.8e-17 64.0 0.0 2.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KII84168.1 - 9.9e-05 22.2 0.1 0.00084 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII84168.1 - 0.002 18.6 0.0 0.0084 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KII84168.1 - 0.0053 16.5 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KII84168.1 - 0.026 14.0 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KII84168.1 - 0.043 14.1 0.9 0.19 12.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KII84168.1 - 0.046 14.0 1.3 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.13 KII84168.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KII84168.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KII84168.1 - 0.087 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII84168.1 - 0.11 13.1 0.4 0.98 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII84168.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KII84168.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_6 PF12774.7 KII84168.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_3 PF07726.11 KII84168.1 - 0.19 11.6 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 KII84169.1 - 7e-23 81.6 6.1 7e-23 81.6 6.1 2.5 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KII84169.1 - 1.3e-16 61.2 0.2 1.5e-14 54.5 0.2 3.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KII84169.1 - 9.5e-05 22.3 0.6 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII84169.1 - 0.0028 18.0 0.0 0.0068 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII84169.1 - 0.02 15.2 0.0 0.22 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KII84169.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KII84169.1 - 0.036 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KII84169.1 - 0.065 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 KII84169.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KII84169.1 - 0.09 13.3 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KII84169.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 KII84169.1 - 0.098 12.6 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 KII84169.1 - 0.19 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ras PF00071.22 KII84170.1 - 5.2e-50 169.2 0.0 6.2e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII84170.1 - 1.8e-23 83.0 0.0 2.6e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII84170.1 - 6.1e-07 29.1 0.0 8.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KII84170.1 - 0.02 14.3 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KII84170.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KII84170.1 - 0.19 11.1 0.0 0.65 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Peptidase_C12 PF01088.21 KII84171.1 - 6.6e-46 156.7 0.0 6.3e-36 124.1 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.25 KII84173.1 - 4.6e-05 22.9 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84173.1 - 0.056 12.7 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FHA PF00498.26 KII84176.1 - 9.8e-16 57.9 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.12 KII84176.1 - 0.00096 19.2 12.6 0.057 13.5 0.6 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KII84176.1 - 0.0074 16.3 6.4 0.69 10.0 3.7 3.1 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Yop-YscD_cpl PF16697.5 KII84176.1 - 0.0092 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SHE3 PF17078.5 KII84176.1 - 0.039 13.7 0.4 0.039 13.7 0.4 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3829 PF12889.7 KII84176.1 - 0.046 13.2 4.2 1.3 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) TRAF_BIRC3_bd PF16673.5 KII84176.1 - 0.057 13.2 0.1 0.057 13.2 0.1 4.3 5 1 0 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain TolA_bind_tri PF16331.5 KII84176.1 - 0.36 10.9 19.9 0.66 10.1 4.4 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation Lipoprotein_7 PF01540.16 KII84176.1 - 0.39 10.0 5.5 1.2 8.3 1.0 2.1 2 0 0 2 2 2 0 Adhesin lipoprotein Fib_alpha PF08702.10 KII84176.1 - 0.55 10.4 5.0 3.5 7.8 0.1 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YabA PF06156.13 KII84176.1 - 0.86 10.3 10.7 2.9 8.6 4.1 2.7 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 KII84176.1 - 0.97 9.8 9.5 1.8 9.0 1.4 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PPP4R2 PF09184.11 KII84176.1 - 2 8.0 16.4 0.028 14.0 7.4 2.2 2 1 0 2 2 2 0 PPP4R2 SKA1 PF07160.12 KII84176.1 - 2 8.2 16.4 0.12 12.3 4.2 3.0 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4795 PF16043.5 KII84176.1 - 3.3 7.3 15.2 7.1 6.2 3.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 KII84176.1 - 6.1 7.4 20.8 0.16 12.4 5.8 3.3 2 2 0 2 2 2 0 Spectrin repeat COG2 PF06148.11 KII84176.1 - 6.5 6.9 15.2 2.7 8.1 0.7 3.8 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 JIP_LZII PF16471.5 KII84176.1 - 8.6 6.6 20.3 0.85 9.8 3.7 4.0 4 0 0 4 4 3 0 JNK-interacting protein leucine zipper II Pkinase PF00069.25 KII84179.1 - 6e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84179.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KII84180.1 - 3.1e-07 30.2 2.5 7.1e-07 29.0 2.5 1.7 1 0 0 1 1 1 1 F-box-like ADH_zinc_N PF00107.26 KII84183.1 - 1.3e-10 41.4 0.1 2.4e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII84183.1 - 3.8e-07 30.0 0.0 1e-05 25.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII84183.1 - 0.0074 17.3 0.1 0.02 16.0 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII84184.1 - 1.2e-11 44.7 0.0 3e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII84184.1 - 1.9e-07 31.0 0.3 6.3e-06 26.0 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII84184.1 - 0.00063 20.8 0.0 0.0012 19.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII84185.1 - 3.3e-11 43.3 0.0 6.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII84185.1 - 1.9e-05 24.5 0.1 0.00036 20.4 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII84185.1 - 0.0025 18.9 0.1 0.0074 17.3 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fe_hyd_lg_C PF02906.14 KII84185.1 - 0.23 11.1 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain F-box-like PF12937.7 KII84186.1 - 1.5e-06 27.9 6.1 1.6e-06 27.9 3.6 2.5 2 0 0 2 2 2 1 F-box-like Meth_synt_2 PF01717.18 KII84187.1 - 9.8e-12 44.8 0.0 1.9e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain X PF00739.19 KII84188.1 - 0.4 10.8 6.3 6.4 6.9 0.1 2.4 1 1 0 2 2 2 0 Trans-activation protein X RIO1 PF01163.22 KII84189.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KII84189.1 - 0.05 13.0 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII84189.1 - 0.059 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain TACI-CRD2 PF09305.10 KII84189.1 - 0.11 12.5 0.8 0.25 11.4 0.5 1.6 2 0 0 2 2 2 0 TACI, cysteine-rich domain Pkinase PF00069.25 KII84190.1 - 0.00065 19.2 0.0 0.00089 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII84190.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.18 KII84192.1 - 5.3e-34 116.4 0.0 8.5e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KII84192.1 - 3.2e-28 98.0 0.4 3.2e-28 98.0 0.4 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain F-box PF00646.33 KII84193.1 - 0.0029 17.5 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain Abhydrolase_9 PF10081.9 KII84193.1 - 0.0055 15.8 5.8 0.09 11.8 1.2 2.8 1 1 1 2 2 2 2 Alpha/beta-hydrolase family F-box-like PF12937.7 KII84193.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like PQQ_3 PF13570.6 KII84193.1 - 0.32 11.6 1.5 43 4.8 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Lycopene_cycl PF05834.12 KII84194.1 - 0.045 12.8 2.6 0.062 12.3 2.6 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein KAR9 PF08580.10 KII84194.1 - 0.53 8.8 7.9 0.62 8.5 7.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 F-box PF00646.33 KII84195.1 - 0.00074 19.3 0.7 0.0016 18.3 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII84195.1 - 0.0062 16.4 0.9 0.013 15.4 0.9 1.5 1 0 0 1 1 1 1 F-box-like Lipase_GDSL_2 PF13472.6 KII84196.1 - 0.002 18.5 0.2 0.0028 18.1 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII84196.1 - 0.0046 17.0 0.0 0.0063 16.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Catalase PF00199.19 KII84196.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Catalase R2K_3 PF14243.6 KII84196.1 - 0.069 13.1 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 3 Aminotran_1_2 PF00155.21 KII84198.1 - 8.4e-28 97.6 0.0 9.9e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KII84198.1 - 0.077 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Dynamin_M PF01031.20 KII84199.1 - 7.1e-31 107.5 0.0 3.2e-30 105.3 0.0 2.0 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KII84199.1 - 2.5e-24 86.2 0.0 5.7e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KII84199.1 - 4.7e-09 36.3 0.4 2.9e-07 30.5 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII84199.1 - 0.0023 18.0 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fungal_trans PF04082.18 KII84200.1 - 4.3e-28 98.1 0.0 7.5e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84201.1 - 1.6e-09 37.7 7.6 2.2e-09 37.3 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.8 KII84202.1 - 6.3e-06 26.1 5.7 6.3e-06 26.1 5.7 2.3 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KII84202.1 - 0.021 14.9 0.1 0.099 12.7 0.1 2.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Ndc1_Nup PF09531.10 KII84202.1 - 0.022 13.5 3.8 0.045 12.5 3.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicty_CAR PF05462.11 KII84202.1 - 1.5 7.8 11.6 0.71 8.9 8.5 2.0 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor DUF3278 PF11683.8 KII84203.1 - 0.046 13.8 8.8 0.13 12.4 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3278) LAB_N PF07578.11 KII84203.1 - 0.14 12.3 4.8 6.8 6.9 0.2 2.8 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Dynamin_M PF01031.20 KII84204.1 - 1.2e-28 100.2 0.0 2.2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KII84204.1 - 4.3e-25 88.7 0.0 1.8e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KII84204.1 - 3e-10 40.1 0.1 9e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII84204.1 - 0.00086 19.4 0.0 0.003 17.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SET PF00856.28 KII84205.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 SET domain Fungal_trans PF04082.18 KII84206.1 - 1.1e-25 90.2 0.2 1.8e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84206.1 - 8.2e-10 38.6 6.6 1.6e-09 37.7 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KII84207.1 - 4.3e-37 128.1 0.0 1e-16 61.2 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 KII84207.1 - 4.8e-34 117.9 0.3 8e-34 117.2 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII84207.1 - 4.2e-06 26.1 0.8 3.5e-05 23.1 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KII84207.1 - 1.5e-05 24.7 2.1 0.0001 22.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII84207.1 - 3e-05 24.1 0.1 0.00011 22.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII84207.1 - 0.0001 21.6 0.1 0.00018 20.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII84207.1 - 0.00017 20.8 0.5 0.00088 18.4 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KII84207.1 - 0.038 13.2 0.1 0.073 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KII84207.1 - 0.075 12.3 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KII84207.1 - 0.14 11.4 2.2 1.1 8.4 0.7 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KII84208.1 - 2.8e-22 79.0 0.0 4.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84208.1 - 1e-06 28.7 7.1 2e-06 27.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OmpH PF03938.14 KII84211.1 - 0.84 10.0 9.8 0.38 11.1 6.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KII84211.1 - 2.9 8.6 9.3 8.9 7.0 0.0 4.2 2 1 2 4 4 4 0 SlyX Aconitase PF00330.20 KII84212.1 - 1.8e-153 511.9 0.0 2.6e-153 511.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KII84212.1 - 5.4e-43 146.5 0.0 9.3e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain STAT2_C PF12188.8 KII84213.1 - 0.037 14.0 0.1 8.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal DNA_RNApol_7kD PF03604.13 KII84218.1 - 1.7 8.4 6.2 4.3 7.1 6.2 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KII84220.1 - 0.08 13.0 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sulfate_transp PF00916.20 KII84221.1 - 2.1e-62 211.1 10.0 2.1e-62 211.1 10.0 1.5 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KII84221.1 - 0.00063 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Myc_target_1 PF15179.6 KII84221.1 - 0.21 11.5 0.3 0.47 10.3 0.2 1.6 2 0 0 2 2 2 0 Myc target protein 1 DUF5427 PF10310.9 KII84223.1 - 1.9 7.3 4.7 2.1 7.2 4.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Rib_hydrolayse PF02267.17 KII84226.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosyl cyclase Baculo_LEF5_C PF11792.8 KII84230.1 - 0.018 14.7 0.5 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain UBN_AB PF14075.6 KII84232.1 - 4.9e-43 147.3 0.0 8.1e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Ubinuclein conserved middle domain HUN PF08729.10 KII84232.1 - 4e-12 46.0 0.0 9.5e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF3097 PF11296.8 KII84232.1 - 0.05 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) GED PF02212.18 KII84233.1 - 0.0015 18.6 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain ADH_zinc_N PF00107.26 KII84236.1 - 1.1e-12 48.1 0.0 3.2e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII84236.1 - 2.4e-07 30.6 0.3 4.2e-06 26.6 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII84236.1 - 0.0077 17.3 0.0 0.085 13.9 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Abi_C PF14355.6 KII84236.1 - 0.15 12.2 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Abortive infection C-terminus Xpo1 PF08389.12 KII84238.1 - 3.5e-15 56.4 0.1 5.3e-12 46.0 0.1 3.9 4 0 0 4 4 4 2 Exportin 1-like protein Importin_rep PF18773.1 KII84238.1 - 3.1e-11 42.8 0.2 9.7e-11 41.2 0.2 1.9 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 KII84238.1 - 0.00049 20.1 0.0 0.002 18.1 0.0 2.2 1 1 0 1 1 1 1 Importin 13 repeat CRM1_C PF08767.11 KII84238.1 - 0.039 13.1 0.6 0.1 11.7 0.1 2.0 2 1 0 2 2 2 0 CRM1 C terminal F-box PF00646.33 KII84240.1 - 0.00025 20.8 0.0 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain TAN PF11640.8 KII84240.1 - 0.074 13.2 0.2 1 9.5 0.1 2.5 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair zf-CRD PF17979.1 KII84240.1 - 1.5 8.9 4.6 8.1 6.5 2.9 2.6 2 1 0 2 2 2 0 Cysteine rich domain with multizinc binding regions SPA PF08616.10 KII84243.1 - 4.2e-31 107.3 0.0 8.5e-31 106.3 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KII84243.1 - 2e-19 70.4 2.6 9.5e-16 58.5 0.1 2.7 3 0 0 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KII84243.1 - 7.2e-05 21.6 0.0 0.028 13.1 0.0 2.9 3 1 0 3 3 3 2 Transport protein Avl9 BAG PF02179.16 KII84244.1 - 0.044 14.2 2.0 0.11 13.0 0.3 2.0 1 1 1 2 2 2 0 BAG domain Cytochrom_B561 PF03188.16 KII84247.1 - 2e-12 47.4 8.5 2e-12 47.4 8.5 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Phage_holin_3_6 PF07332.11 KII84247.1 - 0.0018 18.3 3.2 0.0018 18.3 3.2 2.7 2 1 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4079 PF13301.6 KII84247.1 - 0.0084 16.3 11.3 0.61 10.2 6.3 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF4079) DUF2427 PF10348.9 KII84247.1 - 0.015 15.0 5.1 0.015 15.0 5.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) CBP_BcsF PF11120.8 KII84247.1 - 0.37 10.9 7.5 3.1 8.0 0.4 2.9 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF DUF4149 PF13664.6 KII84247.1 - 1.5 9.2 10.0 0.1 12.9 3.4 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Coatomer_WDAD PF04053.14 KII84248.1 - 1.1e-137 459.8 0.0 2.8e-137 458.4 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KII84248.1 - 5.1e-112 374.6 0.0 7.3e-112 374.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KII84248.1 - 4.6e-46 153.8 9.3 9.4e-08 32.6 0.2 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII84248.1 - 9.3e-11 41.9 0.1 0.037 14.3 0.0 6.3 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KII84248.1 - 0.018 15.8 6.8 5.6 8.1 0.4 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 KII84248.1 - 0.021 14.7 0.4 0.062 13.2 0.1 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 KII84248.1 - 0.11 11.1 0.4 3.5 6.2 0.2 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 KII84248.1 - 0.27 11.5 0.9 9.2 6.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TarH PF02203.15 KII84249.1 - 0.13 12.1 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue RNase_H PF00075.24 KII84250.1 - 1.7e-25 89.8 0.0 3.4e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KII84250.1 - 7.8e-05 23.3 3.8 8.5e-05 23.2 2.2 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KII84250.1 - 0.52 10.3 3.3 0.68 10.0 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RVT_1 PF00078.27 KII84251.1 - 6.8e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 KII84252.1 - 0.04 13.4 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family XPG_I PF00867.18 KII84254.1 - 5.2e-14 52.4 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KII84254.1 - 1.5e-05 25.4 0.0 3.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KII84254.1 - 0.00029 21.4 0.0 0.00094 19.7 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold zf-C2H2_jaz PF12171.8 KII84257.1 - 6.6e-06 26.3 4.6 0.0072 16.6 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KII84257.1 - 0.032 14.7 20.5 1 10.0 4.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 KII84257.1 - 0.046 14.1 7.9 1.7 9.1 2.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII84257.1 - 0.75 10.8 21.8 1.8 9.6 1.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KII84257.1 - 1.4 8.8 8.1 1.2 9.0 3.3 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type LSM PF01423.22 KII84259.1 - 1.9e-19 69.1 1.4 2.4e-19 68.8 1.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII84259.1 - 0.0026 17.9 0.1 0.0033 17.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 KII84259.1 - 0.019 14.9 0.2 0.038 13.9 0.2 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 KII84259.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) tRNA-synt_2 PF00152.20 KII84260.1 - 7.8e-84 281.4 0.0 9.2e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KII84260.1 - 8.2e-12 44.9 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KII84260.1 - 0.0056 16.9 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.10 KII84260.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain zf-MYND PF01753.18 KII84262.1 - 1.4e-07 31.5 12.7 3.9e-07 30.0 12.7 1.8 1 1 0 1 1 1 1 MYND finger Toxin_27 PF08099.11 KII84262.1 - 0.0035 17.4 1.6 0.0035 17.4 1.6 2.5 3 0 0 3 3 3 1 Scorpion calcine family Dysbindin PF04440.16 KII84262.1 - 0.094 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Methyltransf_23 PF13489.6 KII84263.1 - 1.6e-17 63.8 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII84263.1 - 2.9e-13 49.9 0.0 8.9e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84263.1 - 1.7e-10 41.4 0.0 2.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII84263.1 - 4.8e-10 40.0 0.0 8.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII84263.1 - 1.9e-09 38.2 0.0 3.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KII84263.1 - 3.2e-05 23.3 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KII84263.1 - 0.00018 21.1 0.0 0.0004 19.9 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase DUF938 PF06080.12 KII84263.1 - 0.00024 20.9 0.0 0.0092 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF938) MTS PF05175.14 KII84263.1 - 0.0013 18.3 0.0 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KII84263.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KII84263.1 - 0.0048 15.9 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GidB PF02527.15 KII84263.1 - 0.0052 16.1 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 KII84263.1 - 0.0059 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KII84263.1 - 0.006 16.3 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 KII84263.1 - 0.011 15.3 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain CMAS PF02353.20 KII84263.1 - 0.021 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 KII84263.1 - 0.061 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 KII84263.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PX PF00787.24 KII84264.1 - 7.9e-19 67.7 0.0 2.6e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 KII84264.1 - 5.4e-14 52.2 0.2 1.8e-13 50.5 0.6 1.6 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_9 PF14604.6 KII84264.1 - 1.9e-06 27.6 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII84264.1 - 2.9e-06 26.8 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF659 PF04937.15 KII84265.1 - 3.2e-07 30.3 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Adhesin_P1 PF03257.13 KII84265.1 - 5.9 7.5 8.7 8.8e+02 0.5 8.7 3.0 1 1 0 1 1 1 0 Mycoplasma adhesin P1 TFIIA PF03153.13 KII84265.1 - 8.1 6.3 9.4 0.92 9.4 3.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 KII84266.1 - 7.9e-14 51.2 5.2 7.9e-14 51.2 5.2 2.2 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KII84266.1 - 1e-06 28.5 0.2 3.1e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KII84266.1 - 0.052 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CCDC117 PF15810.5 KII84266.1 - 1.4 9.2 3.4 3.4 8.0 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 Rep_fac-A_3 PF08661.11 KII84267.1 - 3.8e-19 69.0 0.3 4e-19 68.9 0.3 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF333 PF03891.15 KII84267.1 - 0.18 12.1 0.1 0.5 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF333) Aldo_ket_red PF00248.21 KII84268.1 - 3.9e-42 144.5 0.0 2.5e-40 138.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KII84269.1 - 1.4e-35 122.5 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII84269.1 - 3.1e-26 92.4 0.0 4.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII84269.1 - 1.3e-08 35.0 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII84269.1 - 2.5e-06 27.5 0.0 1.2e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding DUF3455 PF11937.8 KII84270.1 - 1e-25 90.9 0.6 1.4e-25 90.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Mlp PF03304.13 KII84271.1 - 0.0076 16.5 1.2 3.8 7.7 0.3 2.2 2 0 0 2 2 2 2 Mlp lipoprotein family DUF948 PF06103.11 KII84271.1 - 0.026 14.8 0.4 4.2 7.7 0.0 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 KII84271.1 - 0.1 13.0 1.7 0.16 12.4 0.7 1.8 1 1 0 2 2 2 0 PhoU domain STN1_2 PF09170.10 KII84271.1 - 0.24 11.6 1.9 0.6 10.3 1.9 1.6 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GldM_N PF12081.8 KII84271.1 - 0.46 10.5 8.1 7.3 6.6 7.9 2.1 1 1 0 1 1 1 0 GldM N-terminal domain PMC2NT PF08066.12 KII84271.1 - 0.61 10.8 5.1 13 6.6 0.2 2.8 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF2570 PF10828.8 KII84271.1 - 1.2 9.0 4.9 19 5.1 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) FUSC PF04632.12 KII84271.1 - 1.7 7.1 2.5 3 6.3 2.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family AD PF09793.9 KII84271.1 - 3.3 7.9 5.0 1.1 9.5 0.7 2.3 1 1 1 2 2 2 0 Anticodon-binding domain RRN3 PF05327.11 KII84271.1 - 4.6 5.7 6.7 2.2 6.7 4.6 1.4 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TBCA PF02970.16 KII84271.1 - 6.6 7.1 14.3 2.6 8.4 7.7 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A Neur_chan_memb PF02932.16 KII84271.1 - 7 6.6 5.1 1.8 8.5 1.0 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PIG-L PF02585.17 KII84272.1 - 7.2e-23 81.7 0.2 9.9e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.10 KII84273.1 - 2.7e-08 34.7 0.0 4.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ank_4 PF13637.6 KII84274.1 - 2.2e-15 56.8 0.0 1.3e-12 47.9 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DnaJ PF00226.31 KII84274.1 - 2.6e-14 53.1 0.0 2.1e-11 43.7 0.0 3.0 2 0 0 2 2 2 2 DnaJ domain Ank_5 PF13857.6 KII84274.1 - 5.8e-11 42.4 0.0 4.1e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII84274.1 - 8.8e-11 42.3 0.0 5.5e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII84274.1 - 1e-09 37.8 0.1 0.016 15.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KII84274.1 - 3.7e-09 36.6 0.3 0.24 11.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat zf_CCCH_4 PF18345.1 KII84274.1 - 4.9e-05 23.2 4.5 8.5e-05 22.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KII84274.1 - 0.00014 21.7 4.0 0.00026 20.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KII84274.1 - 0.0032 18.1 0.2 0.0032 18.1 0.2 3.9 3 1 2 5 5 5 1 Torus domain zf-CCCH_4 PF18044.1 KII84274.1 - 0.0052 16.6 2.4 0.0086 15.9 2.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KII84274.1 - 0.03 14.8 0.5 0.052 14.0 0.5 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 KII84275.1 - 5.2e-06 26.1 8.2 0.18 11.9 0.2 4.3 4 0 0 4 4 4 3 Leucine Rich repeat F-box PF00646.33 KII84275.1 - 0.074 12.9 0.4 0.15 11.9 0.4 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KII84275.1 - 0.1 12.5 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 F-box-like FERM_N PF09379.10 KII84275.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 FERM N-terminal domain ABC_tran PF00005.27 KII84276.1 - 1.7e-19 70.7 0.9 4e-09 37.1 0.2 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII84276.1 - 7.8e-07 28.7 1.2 0.0046 16.4 0.1 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KII84276.1 - 3.6e-06 27.0 0.0 0.044 13.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KII84276.1 - 0.00017 21.8 0.0 0.2 11.9 0.0 2.7 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KII84276.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII84276.1 - 0.011 16.2 0.1 0.08 13.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KII84276.1 - 0.012 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KII84276.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KII84276.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KII84276.1 - 0.05 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KII84276.1 - 0.063 12.6 0.1 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RsgA_GTPase PF03193.16 KII84276.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KII84276.1 - 0.07 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KII84276.1 - 0.077 13.0 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KII84276.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII84276.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KII84276.1 - 0.12 12.1 0.1 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KII84276.1 - 0.21 10.2 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KII84276.1 - 0.22 12.0 3.6 0.24 11.9 0.6 2.1 2 0 0 2 2 2 0 AAA domain Rotamase_3 PF13616.6 KII84277.1 - 1.3e-17 64.4 0.1 2.8e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KII84277.1 - 8.8e-14 52.2 0.5 2e-13 51.1 0.5 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KII84277.1 - 0.0056 17.5 2.8 0.037 14.9 2.8 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain Myb_DNA-binding PF00249.31 KII84278.1 - 2.4e-09 37.2 0.0 5.7e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII84278.1 - 1.9e-06 28.0 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KII84278.1 - 1.5e-05 24.8 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like HPHLAWLY PF14925.6 KII84278.1 - 0.0056 15.4 0.0 0.007 15.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF4588 PF15251.6 KII84280.1 - 0.15 11.8 0.9 0.26 11.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PIG-S PF10510.9 KII84281.1 - 2.8e-114 382.8 5.2 2.6e-113 379.6 5.2 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF4087 PF13316.6 KII84282.1 - 0.019 15.4 0.7 6.3 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4087) CBM49 PF09478.10 KII84282.1 - 0.063 13.6 0.9 1.2e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 Carbohydrate binding domain CBM49 Big_3_5 PF16640.5 KII84282.1 - 4.2 7.6 9.7 2.6 8.3 0.9 3.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Oxidored_q2 PF00420.24 KII84282.1 - 10 5.8 8.7 9 6.0 0.1 3.9 4 0 0 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CLTH PF10607.9 KII84283.1 - 1.7e-30 105.9 0.0 3.5e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Med28 PF11594.8 KII84283.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 HlyIII PF03006.20 KII84284.1 - 2e-55 188.0 17.0 2.7e-55 187.5 17.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related PhrC_PhrF PF11131.8 KII84284.1 - 0.27 10.9 9.9 0.68 9.6 2.1 3.2 3 0 0 3 3 3 0 Rap-phr extracellular signalling ABC2_membrane_5 PF13346.6 KII84284.1 - 2.9 7.4 13.6 0.15 11.6 6.8 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein TMEM18 PF14770.6 KII84284.1 - 4.7 7.2 6.7 11 6.0 2.6 2.4 2 1 0 2 2 2 0 Transmembrane protein 18 Oxidored_q2 PF00420.24 KII84284.1 - 5.7 6.6 8.0 4.8 6.9 1.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L p450 PF00067.22 KII84285.1 - 3.6e-32 111.7 0.0 6.3e-32 110.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.11 KII84286.1 - 2.5e-13 50.6 1.0 3.9e-13 49.9 1.0 1.3 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KII84286.1 - 2.7e-05 24.4 7.4 5.5e-05 23.4 7.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF737 PF05300.11 KII84286.1 - 0.016 15.6 2.6 0.023 15.1 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Put_DNA-bind_N PF06971.13 KII84286.1 - 0.087 12.9 0.0 9.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Cofilin_ADF PF00241.20 KII84287.1 - 2.6e-24 85.4 0.0 2.9e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.25 KII84288.1 - 4.1e-15 56.1 0.0 5.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII84288.1 - 6e-07 29.8 0.0 8.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII84288.1 - 7.5e-06 25.9 0.0 9.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII84288.1 - 0.0013 19.4 0.0 0.0017 19.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII84288.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein NAC PF01849.18 KII84289.1 - 2.7e-23 81.7 0.1 4.3e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 NAC domain Glyco_hydro_61 PF03443.14 KII84290.1 - 3e-51 174.3 0.0 3.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase_fungal PF17667.1 KII84291.1 - 1.8e-54 185.1 1.3 1.6e-26 93.0 0.0 2.4 2 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KII84291.1 - 0.017 14.5 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain MRP-L27 PF09809.9 KII84292.1 - 7.4e-06 25.8 0.3 0.0087 15.9 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L27 Ribo_biogen_C PF04034.13 KII84293.1 - 1.1e-33 115.7 0.0 1.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KII84293.1 - 5.2e-10 39.0 0.1 9.3e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PsbN PF02468.15 KII84294.1 - 0.62 10.0 2.8 0.95 9.4 2.8 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Pkinase_fungal PF17667.1 KII84295.1 - 1.2e-53 182.4 0.0 2.2e-53 181.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII84295.1 - 0.00053 19.4 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain LIM PF00412.22 KII84296.1 - 1.1e-29 102.4 22.6 5.5e-11 42.5 5.0 4.2 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 KII84296.1 - 0.052 13.2 11.1 0.25 11.0 0.8 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Ribosomal_L37e PF01907.19 KII84296.1 - 0.19 11.9 13.9 0.27 11.4 0.0 3.6 3 1 0 3 3 3 0 Ribosomal protein L37e zf_UBZ PF18439.1 KII84296.1 - 1.1 8.9 0.1 1.1 8.9 0.1 6.2 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_2 PF13923.6 KII84296.1 - 5 7.0 21.9 2.2 8.2 0.1 4.6 4 2 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Mut7-C PF01927.16 KII84296.1 - 6.7 6.8 14.2 0.23 11.5 1.6 2.6 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-C2H2 PF00096.26 KII84296.1 - 7.4 7.2 13.2 0.92 10.1 0.2 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3494 PF11999.8 KII84298.1 - 3.9e-57 193.3 22.2 3.9e-57 193.3 22.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3494) Kinesin PF00225.23 KII84299.1 - 5.5e-92 308.2 0.0 5.5e-92 308.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KII84299.1 - 8.3e-23 81.0 0.0 1.5e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 KII84299.1 - 0.0038 17.2 0.1 0.0071 16.4 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII84299.1 - 0.0062 16.5 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII84299.1 - 0.043 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII84299.1 - 0.051 14.4 0.3 0.051 14.4 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Serglycin PF04360.12 KII84299.1 - 0.2 11.6 10.0 0.44 10.5 9.3 1.9 2 0 0 2 2 2 0 Serglycin Presenilin PF01080.17 KII84299.1 - 1.8 7.2 19.1 3.3 6.4 19.1 1.4 1 0 0 1 1 1 0 Presenilin Sel1 PF08238.12 KII84301.1 - 2.3e-19 69.4 13.1 1.2e-06 29.0 0.1 6.6 6 0 0 6 6 6 4 Sel1 repeat TPR_2 PF07719.17 KII84301.1 - 0.0034 17.4 7.6 0.0036 17.3 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII84301.1 - 0.0048 16.7 0.2 0.097 12.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII84301.1 - 0.036 14.3 0.0 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII84301.1 - 0.13 13.1 6.3 5.1 8.2 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat Ribosomal_L16 PF00252.18 KII84302.1 - 6.9e-44 149.1 0.0 8.5e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAS_9 PF13426.7 KII84303.1 - 1.7e-27 95.7 0.0 1.8e-15 57.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KII84303.1 - 1.1e-17 64.0 0.0 0.0001 22.3 0.0 4.0 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 KII84303.1 - 2.8e-14 53.2 0.0 1.9e-05 24.8 0.0 4.4 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.10 KII84303.1 - 1.5e-11 44.5 0.0 0.00035 20.8 0.0 4.1 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.6 KII84303.1 - 0.00042 20.4 0.0 0.0014 18.7 0.0 1.9 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 KII84303.1 - 0.003 17.5 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_12 PF18095.1 KII84303.1 - 0.16 11.6 0.0 2.2 7.9 0.0 2.6 3 0 0 3 3 3 0 UPF0242 C-terminal PAS-like domain DUF676 PF05057.14 KII84304.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FGGY_C PF02782.16 KII84305.1 - 4.4e-48 163.6 0.1 6.8e-48 163.0 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KII84305.1 - 3e-20 72.8 0.0 1.4e-19 70.7 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KII84305.1 - 0.0048 16.4 0.1 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PSD4 PF07631.11 KII84305.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) AreA_N PF07573.11 KII84305.1 - 0.097 13.3 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus Aldo_ket_red PF00248.21 KII84306.1 - 7.9e-68 228.8 0.0 9e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BCDHK_Adom3 PF10436.9 KII84307.1 - 1.2e-65 220.3 0.0 1.7e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KII84307.1 - 4.5e-13 49.7 0.0 1.4e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KII84307.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3719 PF12516.8 KII84307.1 - 0.28 10.9 0.9 1 9.1 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3719) PEP-utilisers_N PF05524.13 KII84308.1 - 0.95 9.7 8.2 3.9 7.7 3.8 2.4 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal APG6_N PF17675.1 KII84308.1 - 3.6 8.1 8.0 12 6.5 8.0 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Plavaka PF18759.1 KII84310.1 - 8e-36 123.9 0.0 1.5e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Lipase_GDSL PF00657.22 KII84311.1 - 5.2e-08 33.1 0.0 7.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII84311.1 - 1.6e-05 25.4 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-C3HC4 PF00097.25 KII84312.1 - 9.6e-07 28.6 1.8 9.6e-07 28.6 1.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII84312.1 - 9.8e-07 28.8 2.2 9.8e-07 28.8 2.2 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KII84312.1 - 1.4e-06 28.0 2.8 1.4e-06 28.0 2.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII84312.1 - 5.1e-06 26.4 4.6 5.1e-06 26.4 4.6 2.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII84312.1 - 5.5e-06 26.6 2.3 5.5e-06 26.6 2.3 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII84312.1 - 0.0035 17.2 10.1 0.0069 16.2 1.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KII84312.1 - 0.016 14.8 0.8 0.016 14.8 0.8 2.3 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type HAP1_N PF04849.13 KII84312.1 - 0.026 13.7 2.3 0.037 13.2 2.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Prok-RING_4 PF14447.6 KII84312.1 - 0.03 14.2 10.6 0.16 11.8 1.5 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 KASH_CCD PF14662.6 KII84312.1 - 0.048 13.5 2.5 0.07 13.0 2.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Baculo_IE-1 PF05290.11 KII84312.1 - 0.055 13.4 0.2 0.055 13.4 0.2 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 KII84312.1 - 0.11 12.5 14.7 0.067 13.2 9.4 3.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 KII84312.1 - 0.22 11.4 3.0 0.23 11.3 0.6 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KII84312.1 - 0.33 10.7 3.0 0.84 9.4 3.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger ZapB PF06005.12 KII84312.1 - 0.36 11.3 6.0 1.5 9.3 6.0 1.9 1 1 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 KII84312.1 - 0.44 10.9 4.0 0.25 11.7 0.5 2.2 2 1 1 3 3 2 0 TSC-22/dip/bun family zf-ANAPC11 PF12861.7 KII84312.1 - 1.3 9.2 4.5 0.74 9.9 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Integrase_H2C2 PF17921.1 KII84312.1 - 3 8.0 7.5 5.1 7.3 0.2 3.3 4 0 0 4 4 3 0 Integrase zinc binding domain zf-rbx1 PF12678.7 KII84312.1 - 3.5 8.0 13.9 1.6 9.1 6.1 3.5 3 1 0 3 3 3 0 RING-H2 zinc finger domain FYVE PF01363.21 KII84312.1 - 6.8 6.9 6.6 2.3 8.4 2.7 2.3 2 1 0 2 2 1 0 FYVE zinc finger BTB PF00651.31 KII84313.1 - 3.7e-10 40.0 0.0 5.2e-09 36.3 0.0 2.7 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.25 KII84313.1 - 2.1e-07 30.9 3.4 1.9e-06 27.8 0.8 2.7 3 0 0 3 3 3 1 CAP-Gly domain Uricase PF01014.18 KII84316.1 - 1e-73 245.8 0.5 5.2e-38 130.3 0.2 2.0 2 0 0 2 2 2 2 Uricase Pkinase PF00069.25 KII84317.1 - 1.4e-66 224.5 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84317.1 - 2e-32 112.5 0.0 5.4e-32 111.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII84317.1 - 9.5e-05 21.8 0.2 0.00016 21.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII84317.1 - 0.00022 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KII84317.1 - 0.00098 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII84317.1 - 0.099 12.5 0.9 2.9 7.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 KII84317.1 - 0.16 11.6 0.1 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CCCH_4 PF18044.1 KII84318.1 - 5e-09 35.7 7.2 6.8e-05 22.6 0.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KII84318.1 - 2e-08 34.9 5.9 0.00031 21.4 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KII84318.1 - 2.9e-06 27.1 12.7 3.2e-05 23.8 1.7 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KII84318.1 - 7.2e-06 25.8 6.8 0.00017 21.4 1.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KII84318.1 - 0.00024 21.3 0.6 0.00046 20.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KII84318.1 - 5.7 7.6 11.8 0.21 12.1 2.3 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger EIF_2_alpha PF07541.12 KII84319.1 - 1.3e-35 122.0 0.0 2.2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KII84319.1 - 2.7e-13 50.1 1.0 5.4e-13 49.1 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S49_N PF08496.10 KII84319.1 - 0.11 12.5 0.8 0.63 10.1 0.0 2.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal CBF PF03914.17 KII84320.1 - 1.2e-31 110.1 5.6 6.9e-29 101.1 2.8 3.2 3 0 0 3 3 3 3 CBF/Mak21 family DUF3376 PF11856.8 KII84320.1 - 0.061 12.3 4.4 0.51 9.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3376) zf-MYND PF01753.18 KII84321.1 - 9.1e-09 35.3 10.8 1.7e-08 34.4 10.8 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII84321.1 - 0.011 16.0 3.7 0.011 16.0 3.7 2.8 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Stanniocalcin PF03298.13 KII84321.1 - 0.18 11.1 3.3 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Stanniocalcin family DIOX_N PF14226.6 KII84323.1 - 5e-16 59.5 0.0 1.1e-15 58.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII84323.1 - 5.7e-15 55.6 0.0 1.6e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ATP-synt_G PF04718.15 KII84325.1 - 3.5e-17 63.1 0.1 1e-16 61.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit HisKA_3 PF07730.13 KII84325.1 - 0.35 11.4 1.6 0.47 11.0 0.1 2.0 3 0 0 3 3 3 0 Histidine kinase Pho88 PF10032.9 KII84326.1 - 1.2e-74 249.5 0.0 1.4e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TMEMspv1-c74-12 PF11044.8 KII84326.1 - 0.022 14.8 1.5 0.052 13.5 0.6 2.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PH PF00169.29 KII84327.1 - 1.3e-06 28.9 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF5098 PF17023.5 KII84327.1 - 0.019 14.0 0.2 4 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) Nnf1 PF03980.14 KII84327.1 - 0.057 13.8 0.6 3.2 8.2 0.2 2.7 2 0 0 2 2 2 0 Nnf1 HTH_18 PF12833.7 KII84327.1 - 0.13 12.6 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_60s PF00428.19 KII84327.1 - 0.14 12.7 3.2 0.31 11.7 3.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Orthopox_A5L PF06193.11 KII84327.1 - 0.98 8.8 3.6 1.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like CENP-B_dimeris PF09026.10 KII84327.1 - 9.7 6.7 9.7 22 5.5 9.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pro_CA PF00484.19 KII84329.1 - 2.4e-34 118.9 0.0 3.9e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ricin_B_lectin PF00652.22 KII84331.1 - 4.3e-15 56.1 0.0 3e-06 27.5 0.0 4.2 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KII84331.1 - 5.2e-08 33.5 2.4 0.11 13.3 0.0 4.8 4 1 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 KII84331.1 - 0.012 15.6 0.0 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 FIST C domain zf-H2C2_2 PF13465.6 KII84332.1 - 2.4e-08 34.1 8.6 8.8e-07 29.1 1.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII84332.1 - 0.00054 20.6 14.0 0.0021 18.7 2.7 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KII84332.1 - 0.00055 20.2 0.3 0.0013 19.0 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KII84332.1 - 0.00062 20.1 3.3 0.00062 20.1 3.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KII84332.1 - 0.035 14.4 1.8 0.65 10.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 KII84332.1 - 0.29 11.0 1.6 0.72 9.7 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KII84332.1 - 0.39 10.5 7.0 0.52 10.1 2.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type BAT2_N PF07001.11 KII84332.1 - 0.58 10.6 17.0 0.042 14.3 9.6 2.5 3 0 0 3 3 3 0 BAT2 N-terminus zf-C2H2_2 PF12756.7 KII84332.1 - 0.94 9.8 6.8 0.83 10.0 0.4 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KII84332.1 - 3 7.9 8.9 0.56 10.3 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_79C PF16862.5 KII84333.1 - 1e-07 32.8 0.0 2.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RPN2_C PF18004.1 KII84334.1 - 0.022 14.7 2.4 0.023 14.6 1.9 1.3 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 KII84334.1 - 0.2 10.8 2.7 0.29 10.3 2.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 KII84334.1 - 1.2 7.3 11.2 1.4 7.0 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.13 KII84334.1 - 2.3 8.0 7.6 0.46 10.3 3.5 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Pes-10 PF07149.11 KII84334.1 - 4.1 6.4 6.6 5.3 6.0 6.6 1.2 1 0 0 1 1 1 0 Pes-10 CENP-B_dimeris PF09026.10 KII84334.1 - 5.5 7.4 16.2 41 4.6 12.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3652 PF12372.8 KII84336.1 - 0.041 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Huntingtin protein region M-factor PF03855.13 KII84336.1 - 0.13 12.4 1.2 3.8 7.8 1.2 2.6 2 0 0 2 2 2 0 M-factor Cpn10 PF00166.21 KII84338.1 - 6.6e-27 93.4 0.0 7.6e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.18 KII84339.1 - 2e-07 31.0 13.9 3.5e-07 30.2 13.9 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KII84340.1 - 2.2e-06 27.4 2.6 6.6e-06 25.9 1.4 2.3 2 0 0 2 2 2 1 F-box-like Pro_CA PF00484.19 KII84341.1 - 7.8e-39 133.5 0.0 1.3e-38 132.7 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase SulA PF03846.14 KII84341.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA Trypan_PARP PF05887.11 KII84344.1 - 1.9 8.4 9.8 3.5 7.6 9.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 KII84344.1 - 5.3 5.0 10.1 7.3 4.6 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Glutaredoxin PF00462.24 KII84345.1 - 8.8e-15 54.7 0.0 2e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KII84345.1 - 5.8e-13 48.7 0.0 1.9e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 KII84345.1 - 8.6e-05 22.5 0.0 0.0025 17.8 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KII84345.1 - 0.086 13.2 0.0 3.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 KII84345.1 - 0.13 12.7 0.0 1.6 9.2 0.0 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain F-box-like PF12937.7 KII84347.1 - 5.4e-07 29.4 1.5 5.4e-07 29.4 1.5 2.2 2 0 0 2 2 2 1 F-box-like DUF5082 PF16888.5 KII84347.1 - 0.0046 17.2 0.1 0.0071 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) LRR_8 PF13855.6 KII84347.1 - 0.13 12.0 0.3 8.7 6.2 0.0 3.6 4 1 0 4 4 4 0 Leucine rich repeat PTPA PF03095.15 KII84348.1 - 1e-88 297.7 0.0 1.3e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PhrC_PhrF PF11131.8 KII84348.1 - 0.2 11.2 0.8 0.39 10.3 0.8 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling DDE_3 PF13358.6 KII84350.1 - 1.6e-07 31.2 0.1 0.00012 21.8 0.1 2.6 2 0 0 2 2 2 2 DDE superfamily endonuclease Orn_Arg_deC_N PF02784.16 KII84351.1 - 7.2e-78 261.4 0.0 9.9e-78 260.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KII84351.1 - 3.3e-16 59.3 0.0 4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 KII84351.1 - 0.14 12.2 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain KilA-N PF04383.13 KII84353.1 - 0.099 12.5 0.1 0.86 9.5 0.1 2.1 1 1 0 1 1 1 0 KilA-N domain FAM199X PF15814.5 KII84353.1 - 0.41 9.7 4.9 0.77 8.7 4.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X Na_sulph_symp PF00939.19 KII84354.1 - 3.1e-32 112.2 30.6 4e-32 111.9 30.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 KII84354.1 - 5.4e-28 99.0 8.2 3.4e-20 73.3 2.4 2.3 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 KII84354.1 - 5.3e-24 84.9 38.3 4.8e-19 68.7 15.9 2.4 1 1 1 2 2 2 2 Citrate transporter PBP1_TM PF14812.6 KII84354.1 - 0.16 12.3 2.7 0.47 10.8 2.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 KII84354.1 - 0.84 9.9 5.7 0.3 11.3 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-MYND PF01753.18 KII84356.1 - 2.4e-07 30.7 11.2 2.4e-07 30.7 11.2 2.4 2 0 0 2 2 2 1 MYND finger zf-C3HC4_3 PF13920.6 KII84357.1 - 3.2e-09 36.5 3.2 1e-08 34.9 3.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII84357.1 - 8.4e-08 32.1 2.1 1.4e-07 31.3 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII84357.1 - 3.3e-07 30.1 0.1 6.4e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII84357.1 - 4.5e-07 29.8 1.6 6.3e-07 29.3 0.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII84357.1 - 7e-06 26.3 1.4 1.3e-05 25.4 1.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII84357.1 - 0.00012 21.8 2.0 0.00012 21.8 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII84357.1 - 0.0014 18.4 9.0 0.023 14.5 9.1 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KII84357.1 - 0.14 11.9 1.0 0.36 10.7 1.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KII84357.1 - 0.43 10.8 6.1 2.8 8.2 6.4 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 KII84357.1 - 0.59 10.2 5.9 1.8 8.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Isochorismatase PF00857.20 KII84358.1 - 0.0016 18.6 0.0 0.0019 18.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family CDH-cyt PF16010.5 KII84359.1 - 1.3e-14 54.3 7.9 1.7e-13 50.7 7.9 2.1 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KII84359.1 - 6.6e-14 52.2 2.3 1.3e-13 51.3 1.1 2.0 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KII84359.1 - 1.1e-09 38.6 0.3 2.1e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KII84359.1 - 3.8e-05 23.4 2.7 0.00013 21.7 2.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KII84359.1 - 0.00018 21.7 7.9 4.2 7.5 0.0 3.6 2 1 1 3 3 3 3 Protein of unknown function (DUF4079) DUF3382 PF11862.8 KII84359.1 - 0.062 13.6 0.2 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Ni_hydr_CYTB PF01292.20 KII84359.1 - 0.24 11.0 7.6 1.5 8.4 8.1 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Phage_holin_3_6 PF07332.11 KII84359.1 - 1.3 9.1 12.0 0.29 11.2 2.2 3.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF998 PF06197.13 KII84359.1 - 6.2 6.4 18.0 1.4 8.5 8.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Hus1 PF04005.12 KII84360.1 - 1.8e-74 250.5 0.0 2.1e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.16 KII84360.1 - 0.025 13.7 0.2 0.039 13.0 0.1 1.4 2 0 0 2 2 2 0 Repair protein Rad1/Rec1/Rad17 Maf PF02545.14 KII84362.1 - 6.6e-44 149.7 0.0 7.7e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein COPIIcoated_ERV PF07970.12 KII84363.1 - 3.1e-37 128.6 0.6 4.5e-37 128.0 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KII84363.1 - 1.8e-22 79.5 0.0 2.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sdh_cyt PF01127.22 KII84364.1 - 1.7e-25 89.4 1.4 2.1e-25 89.1 1.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pheromone PF08015.11 KII84365.1 - 2.6e-05 25.2 4.0 3.9e-05 24.6 4.0 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone MINDY_DUB PF04424.13 KII84366.1 - 9.1e-28 96.6 0.0 1.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase PRCC PF10253.9 KII84366.1 - 2.9 8.6 10.3 1.5 9.6 0.1 2.5 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pheromone PF08015.11 KII84367.1 - 3e-06 28.2 2.0 0.048 14.7 0.2 2.5 2 1 0 2 2 2 2 Fungal mating-type pheromone Helicase_C PF00271.31 KII84369.1 - 4.2e-13 49.6 0.0 1.5e-12 47.8 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII84369.1 - 1.1e-11 44.8 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Asp_Glu_race PF01177.22 KII84370.1 - 1.1e-06 28.7 0.0 6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 KII84370.1 - 0.0071 15.8 0.2 0.017 14.5 0.1 1.6 2 0 0 2 2 2 1 AroM protein Amdase PF17645.1 KII84370.1 - 0.065 12.9 0.3 0.17 11.5 0.1 1.7 1 1 1 2 2 2 0 Arylmalonate decarboxylase LRR_4 PF12799.7 KII84371.1 - 0.0029 18.0 1.6 0.021 15.3 0.1 2.8 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KII84371.1 - 0.24 11.6 2.5 83 3.6 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat RabGAP-TBC PF00566.18 KII84372.1 - 7.1e-50 169.6 0.0 1.1e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COX6B PF02297.17 KII84373.1 - 1e-20 73.7 3.4 1.3e-20 73.4 3.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KII84373.1 - 0.049 13.9 1.1 0.15 12.4 1.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF4451 PF14616.6 KII84375.1 - 0.032 14.4 0.5 25 5.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) TPR_2 PF07719.17 KII84376.1 - 3.2e-08 33.1 7.9 0.0029 17.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII84376.1 - 2.8e-07 31.0 3.4 0.00027 21.5 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII84376.1 - 4.2e-07 29.5 5.2 0.0054 16.5 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII84376.1 - 1.4e-05 24.7 2.6 0.0075 15.9 0.8 2.8 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KII84376.1 - 3.8e-05 24.1 2.3 0.00076 19.9 0.2 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII84376.1 - 0.0022 18.6 9.6 0.14 13.0 0.3 4.1 3 1 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII84376.1 - 0.0098 16.0 0.8 0.82 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII84376.1 - 0.015 15.3 5.7 0.52 10.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KII84376.1 - 0.017 15.2 0.5 4.8 7.3 0.1 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KII84376.1 - 0.064 13.6 0.8 0.064 13.6 0.8 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KII84376.1 - 0.065 13.7 2.1 1.7 9.0 2.0 2.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 KII84376.1 - 0.64 10.8 0.1 0.64 10.8 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat HemY_N PF07219.13 KII84376.1 - 6.1 7.1 6.3 14 6.0 0.6 2.8 1 1 1 2 2 2 0 HemY protein N-terminus DDE_3 PF13358.6 KII84378.1 - 7.9e-09 35.4 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KII84379.1 - 0.0024 18.1 0.0 0.0028 17.9 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.6 KII84379.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix CoaE PF01121.20 KII84379.1 - 0.11 12.2 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Dephospho-CoA kinase MFS_1 PF07690.16 KII84380.1 - 1.3e-18 67.1 32.8 1.7e-11 43.7 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII84380.1 - 5.2e-15 55.2 5.0 5.2e-15 55.2 5.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter FmdA_AmdA PF03069.15 KII84381.1 - 2.9e-153 510.1 0.0 3.5e-153 509.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.29 KII84382.1 - 0.00062 19.8 0.0 0.0098 16.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KII84382.1 - 0.023 15.2 0.1 0.69 10.4 0.0 2.9 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain KH_6 PF15985.5 KII84382.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 KH domain RNase_P_Rpp14 PF01900.19 KII84384.1 - 1.3e-27 96.0 0.0 1.7e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RVT_1 PF00078.27 KII84386.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BORCS8 PF10167.9 KII84386.1 - 0.089 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 RNase_H PF00075.24 KII84387.1 - 4.4e-13 49.6 0.0 8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KII84387.1 - 1.8e-05 25.3 5.0 2.3e-05 25.0 3.4 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Aminotran_1_2 PF00155.21 KII84388.1 - 3.7e-32 111.9 0.0 4.6e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII84388.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_cc PF11790.8 KII84389.1 - 8e-66 222.0 0.1 9.4e-66 221.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PTCB-BRCT PF12738.7 KII84392.1 - 3e-27 94.4 0.0 1.9e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KII84392.1 - 1.2e-19 70.5 0.0 1.4e-06 28.6 0.0 3.9 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KII84392.1 - 0.014 15.7 0.0 1.1 9.7 0.0 3.1 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain NepR PF18557.1 KII84392.1 - 0.3 10.8 1.6 0.33 10.6 0.3 1.8 2 0 0 2 2 2 0 Anti-sigma factor NepR CK_II_beta PF01214.18 KII84393.1 - 1.9e-79 265.7 0.0 2.2e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1833 PF08875.11 KII84393.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) MBOAT PF03062.19 KII84394.1 - 2.7e-48 165.1 20.6 3.6e-48 164.7 19.7 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Cas3_C PF18395.1 KII84394.1 - 0.15 12.5 0.1 0.31 11.6 0.1 1.4 1 0 0 1 1 1 0 Cas3 C-terminal domain FAD_binding_3 PF01494.19 KII84395.1 - 2.6e-21 76.2 0.1 7.1e-21 74.8 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII84395.1 - 7.6e-12 45.5 3.2 3.1e-07 30.3 1.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII84395.1 - 9.9e-10 38.1 1.0 1.4e-08 34.4 0.2 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KII84395.1 - 4.8e-08 32.7 0.1 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII84395.1 - 5.3e-07 29.8 0.5 1.6e-06 28.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII84395.1 - 1e-06 28.2 0.1 1.9e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII84395.1 - 6.5e-06 25.1 0.2 1.2e-05 24.2 0.2 1.4 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KII84395.1 - 3.8e-05 23.1 0.1 0.00051 19.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII84395.1 - 4.1e-05 24.1 2.7 0.00087 19.8 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII84395.1 - 0.00037 19.6 0.4 0.35 9.9 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KII84395.1 - 0.00073 18.5 0.0 0.058 12.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KII84395.1 - 0.0016 17.8 0.1 0.0032 16.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KII84395.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII84395.1 - 0.003 17.6 0.7 0.67 9.9 0.1 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 KII84395.1 - 0.006 15.7 1.5 0.015 14.4 1.5 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KII84395.1 - 0.023 13.9 0.2 0.085 12.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 KII84395.1 - 0.037 13.6 0.0 1 8.9 0.1 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Endonuc-EcoRV PF09233.11 KII84395.1 - 0.2 11.0 0.1 0.33 10.3 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRV zf-RVT PF13966.6 KII84396.1 - 6.7e-05 23.5 0.7 0.00014 22.5 0.7 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CdvA PF18822.1 KII84399.1 - 0.0017 18.2 1.0 0.0025 17.6 1.0 1.2 1 0 0 1 1 1 1 CdvA-like coiled-coil domain DUF4482 PF14818.6 KII84399.1 - 0.085 13.7 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Atg14 PF10186.9 KII84399.1 - 3.1 6.8 5.2 4.4 6.3 5.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4139 PF13598.6 KII84403.1 - 9.7e-22 77.7 0.0 2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KII84403.1 - 1.9e-19 69.9 1.0 3.2e-17 62.7 1.0 2.5 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 KII84403.1 - 7.1e-09 36.4 42.3 1.1e-07 32.6 23.7 3.1 3 1 1 4 4 4 2 Nucleoporin FG repeat region Ribosomal_L30 PF00327.20 KII84404.1 - 7e-11 41.8 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Abhydrolase_6 PF12697.7 KII84405.1 - 2.3e-27 97.0 0.5 2.3e-27 97.0 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII84405.1 - 3.2e-08 33.1 0.0 5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII84405.1 - 8.4e-08 32.2 0.0 7.8e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KII84405.1 - 1.4e-05 25.4 0.0 3.2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KII84405.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KII84405.1 - 0.069 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 KII84405.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF563 PF04577.14 KII84406.1 - 0.041 14.0 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Gag_p6 PF08705.11 KII84407.1 - 0.024 14.9 0.5 0.12 12.6 0.5 2.2 1 0 0 1 1 1 0 Gag protein p6 Mid2 PF04478.12 KII84407.1 - 0.099 12.5 0.0 0.099 12.5 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Pentapeptide_4 PF13599.6 KII84409.1 - 0.011 15.8 1.8 0.049 13.8 1.1 2.1 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Pox_A_type_inc PF04508.12 KII84411.1 - 0.059 13.2 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Big_4 PF07532.11 KII84411.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) DUF3220 PF11516.8 KII84413.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) ANAPC3 PF12895.7 KII84415.1 - 8e-25 86.9 4.2 6.3e-10 39.2 0.0 5.8 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KII84415.1 - 5.7e-23 79.1 1.1 2e-05 24.4 0.0 8.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KII84415.1 - 1.5e-22 78.4 0.4 1.5e-08 34.1 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII84415.1 - 5.9e-18 64.9 1.8 1.8e-10 41.0 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII84415.1 - 1.2e-14 53.2 0.0 3.8e-05 23.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII84415.1 - 5.1e-14 52.5 0.6 9.1e-05 22.9 0.2 5.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KII84415.1 - 2.5e-12 45.9 0.1 0.012 15.6 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII84415.1 - 1.1e-11 45.2 5.6 5.4e-05 23.8 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII84415.1 - 1e-08 34.9 0.2 4.6 7.9 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII84415.1 - 2.7e-08 33.9 13.6 0.00049 20.6 0.0 7.5 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KII84415.1 - 1.7e-07 30.9 1.2 0.018 14.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII84415.1 - 2.6e-07 30.2 2.2 0.041 13.6 0.0 5.3 6 1 1 7 7 7 2 TPR repeat TPR_14 PF13428.6 KII84415.1 - 2.3e-06 27.9 1.0 0.14 13.0 0.0 5.4 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KII84415.1 - 5e-05 22.8 0.2 0.019 14.3 0.1 2.8 2 0 0 2 2 2 2 MalT-like TPR region Fis1_TPR_C PF14853.6 KII84415.1 - 0.00042 20.3 0.1 0.027 14.5 0.1 3.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 KII84415.1 - 0.0012 19.2 0.5 6.3 7.7 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII84415.1 - 0.0017 18.5 1.1 0.26 11.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3887 PF13026.6 KII84415.1 - 0.082 13.7 0.2 0.23 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) eIF-1a PF01176.19 KII84416.1 - 2.6e-23 81.6 0.0 3.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RRM_1 PF00076.22 KII84418.1 - 9.9e-16 57.3 0.0 1.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KII84418.1 - 0.046 14.0 0.2 0.23 11.7 0.0 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 KII84418.1 - 0.046 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KII84418.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 KII84418.1 - 0.19 11.9 0.0 0.46 10.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Sugar_tr PF00083.24 KII84420.1 - 3.6e-52 177.7 20.0 4.4e-52 177.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII84420.1 - 1.1e-24 87.0 31.3 1.5e-23 83.3 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KII84421.1 - 1.1e-08 34.5 0.0 2.9e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84421.1 - 0.024 14.7 12.9 0.041 14.0 12.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Maf1 PF09174.10 KII84422.1 - 9.1e-41 139.9 0.0 8.2e-34 117.3 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator p450 PF00067.22 KII84423.1 - 5.6e-70 236.4 0.0 6.6e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_LYR PF05347.15 KII84424.1 - 1.7e-12 47.2 0.2 1.7e-12 47.2 0.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KII84424.1 - 0.00014 22.5 0.8 0.00018 22.2 0.8 1.2 1 1 0 1 1 1 1 Complex1_LYR-like SCP2 PF02036.17 KII84425.1 - 2.2e-24 85.8 1.2 2.8e-24 85.5 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KII84425.1 - 7.1e-06 26.3 0.6 9.1e-06 26.0 0.6 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KII84425.1 - 0.019 15.3 0.1 0.035 14.5 0.1 1.5 1 1 0 1 1 1 0 Sterol carrier protein domain Dynamin_N PF00350.23 KII84426.1 - 1.2e-41 142.5 0.0 2.4e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KII84426.1 - 6e-09 35.5 0.0 1.7e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KII84426.1 - 0.00014 21.9 0.0 0.00075 19.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DHDPS PF00701.22 KII84427.1 - 1.3e-43 148.8 0.0 1.6e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KII84427.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Med22 PF06179.12 KII84428.1 - 2.6e-18 66.2 1.6 3.2e-18 65.9 1.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex WD40 PF00400.32 KII84429.1 - 0.0041 17.9 0.3 0.37 11.7 0.1 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Acetyltransf_10 PF13673.7 KII84430.1 - 4.6e-11 42.8 0.0 1.3e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII84430.1 - 2.9e-10 40.4 0.0 1.8e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII84430.1 - 3.8e-10 40.0 0.0 5.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KII84430.1 - 0.0013 18.8 0.4 0.021 14.9 0.1 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII84430.1 - 0.059 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pkinase_fungal PF17667.1 KII84431.1 - 6.2e-58 196.5 1.1 1.8e-57 194.9 1.1 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII84431.1 - 8e-05 22.1 0.0 0.00022 20.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84431.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.7 KII84432.1 - 1.3e-09 37.8 0.6 1.3e-09 37.8 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII84432.1 - 0.074 12.9 4.0 5.5 7.0 2.1 3.3 3 0 0 3 3 3 0 F-box domain DUF1748 PF08520.10 KII84433.1 - 4e-23 81.1 0.0 4.5e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Serinc PF03348.15 KII84434.1 - 2.3e-164 547.4 6.6 2.6e-164 547.2 6.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CENP-B_dimeris PF09026.10 KII84434.1 - 0.048 14.1 0.5 0.099 13.0 0.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F-box-like PF12937.7 KII84436.1 - 6.5e-08 32.3 1.1 1.5e-07 31.2 1.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII84436.1 - 0.082 13.4 0.0 7.9 7.1 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_18 PF00704.28 KII84437.1 - 7.3e-22 78.5 1.3 1.5e-21 77.4 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 OB_Dis3 PF17849.1 KII84437.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Dis3-like cold-shock domain 2 (CSD2) Pes-10 PF07149.11 KII84437.1 - 0.35 9.9 0.2 0.6 9.1 0.2 1.3 1 0 0 1 1 1 0 Pes-10 Rad51 PF08423.11 KII84438.1 - 1.2e-16 60.8 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KII84438.1 - 4.9e-08 32.8 0.1 1e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KII84438.1 - 6e-07 29.0 0.0 4.9e-06 26.1 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 KII84438.1 - 2.8e-06 27.1 0.0 2.5e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KII84438.1 - 1.3e-05 24.7 0.0 2.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain CobU PF02283.16 KII84438.1 - 0.0051 16.4 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase_2 PF01637.18 KII84438.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KII84438.1 - 0.02 15.2 0.1 0.035 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain PAXNEB PF05625.11 KII84438.1 - 0.025 13.7 0.5 3 6.9 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein Disulph_isomer PF06491.11 KII84438.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Disulphide isomerase Ribosomal_S10 PF00338.22 KII84439.1 - 2.1e-28 98.4 0.4 2.5e-28 98.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF572 PF04502.13 KII84440.1 - 1.3e-66 225.5 1.5 1.5e-66 225.3 1.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Aminotran_1_2 PF00155.21 KII84441.1 - 2.9e-23 82.6 0.0 3.5e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KII84441.1 - 2.5e-10 39.8 0.0 3.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ISG65-75 PF11727.8 KII84441.1 - 0.0061 15.8 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein Polysacc_deac_2 PF04748.13 KII84441.1 - 0.17 11.0 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase F-box-like PF12937.7 KII84442.1 - 4.9e-10 39.1 3.6 1.4e-09 37.7 3.6 1.9 1 0 0 1 1 1 1 F-box-like ARID PF01388.21 KII84443.1 - 5.5e-13 49.4 3.0 6.3e-12 46.0 0.0 3.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 KII84443.1 - 3.1e-05 24.2 1.0 3.1e-05 24.2 1.0 4.6 3 1 0 4 4 4 2 Mediator complex subunit 15 Phage_TAC_6 PF09550.10 KII84443.1 - 0.078 13.4 0.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC F-box-like PF12937.7 KII84445.1 - 1.5e-07 31.2 0.0 3.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF1515 PF07439.11 KII84445.1 - 0.045 13.8 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) SNARE_assoc PF09335.11 KII84446.1 - 7.8e-12 45.7 5.3 7.8e-12 45.7 5.3 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein Fungal_trans PF04082.18 KII84447.1 - 5.5e-13 48.5 0.0 8.1e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.31 KII84448.1 - 5.1e-17 61.8 0.4 1.3e-16 60.5 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain cobW PF02492.19 KII84449.1 - 1.6e-40 138.5 0.0 2.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KII84449.1 - 0.0085 16.0 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF1574 PF07611.11 KII84449.1 - 0.051 12.9 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) CobW_C PF07683.14 KII84449.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KII84449.1 - 0.064 13.6 0.0 0.099 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 KII84449.1 - 0.18 11.2 0.1 0.4 10.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein DnaJ PF00226.31 KII84450.1 - 1.3e-24 86.1 1.2 2.8e-24 85.0 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KII84450.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII84450.1 - 8.8e-05 22.8 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Mei5_like PF17021.5 KII84450.1 - 0.037 14.1 1.4 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Putative double-strand recombination repair-like MBF1 PF08523.10 KII84450.1 - 0.044 14.2 0.6 0.044 14.2 0.6 2.3 2 0 0 2 2 2 0 Multiprotein bridging factor 1 Prp18 PF02840.15 KII84451.1 - 6.6e-62 207.8 0.2 6.6e-62 207.8 0.2 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KII84451.1 - 6.1e-11 41.7 4.6 1.5e-10 40.4 4.6 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Macoilin PF09726.9 KII84451.1 - 0.39 9.2 8.0 0.049 12.2 3.7 1.6 1 1 0 1 1 1 0 Macoilin family Pinin_SDK_memA PF04696.13 KII84451.1 - 2.9 8.0 17.7 0.25 11.4 6.3 3.0 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region COX6B PF02297.17 KII84452.1 - 3.7e-19 68.7 7.0 4.3e-19 68.5 7.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KII84452.1 - 0.0078 16.3 0.8 0.024 14.8 0.8 1.9 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 KII84452.1 - 0.042 13.9 1.7 0.069 13.2 1.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KII84452.1 - 3.1 8.1 8.7 7.9 6.8 1.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) zf-Tim10_DDP PF02953.15 KII84453.1 - 2.9e-22 78.1 1.1 3.8e-22 77.7 1.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.11 KII84453.1 - 0.091 12.8 0.6 0.11 12.5 0.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Beta-lactamase PF00144.24 KII84454.1 - 1.2e-39 136.5 0.0 3.3e-39 135.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KII84454.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Adaptin_N PF01602.20 KII84456.1 - 6.6e-115 384.6 1.0 9.5e-115 384.1 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KII84456.1 - 2.5e-12 47.1 1.4 1.4e-09 38.2 0.0 3.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII84456.1 - 1.6e-07 31.6 1.0 0.032 14.6 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KII84456.1 - 0.00048 20.2 2.7 1.6 9.2 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat SAPS PF04499.15 KII84456.1 - 0.4 9.4 4.9 0.77 8.5 4.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 KII84456.1 - 0.65 10.3 6.6 1.2 9.5 6.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BSP_II PF05432.11 KII84456.1 - 1 9.0 27.1 1.5 8.4 27.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.11 KII84456.1 - 4.6 5.2 12.1 7.3 4.5 12.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 KII84456.1 - 7.8 6.2 9.7 12 5.7 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 KII84456.1 - 7.9 5.8 12.8 14 4.9 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Homeodomain PF00046.29 KII84457.1 - 1.5e-18 66.4 1.3 2.7e-18 65.6 1.3 1.4 1 0 0 1 1 1 1 Homeodomain FlhE PF06366.13 KII84457.1 - 0.04 13.9 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlhE U1snRNP70_N PF12220.8 KII84458.1 - 1.9e-26 92.5 0.4 2.8e-26 92.0 0.4 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KII84458.1 - 7.3e-16 57.8 0.0 1.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4799 PF16056.5 KII84458.1 - 0.084 12.0 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) zf-C2H2_jaz PF12171.8 KII84459.1 - 0.0054 17.0 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KII84459.1 - 0.051 13.9 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KII84459.1 - 0.18 12.2 0.3 0.29 11.6 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type MRNIP PF15749.5 KII84459.1 - 0.19 12.4 0.1 0.19 12.4 0.1 2.1 2 0 0 2 2 2 0 MRN-interacting protein CTU2 PF10288.9 KII84459.1 - 0.64 10.3 3.9 0.37 11.1 0.6 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 SMN PF06003.12 KII84459.1 - 1.4 8.2 6.4 0.068 12.4 1.2 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Glyco_hydro_79C PF16862.5 KII84460.1 - 7.9e-16 58.8 2.3 1.5e-15 57.9 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain NAR PF16251.5 KII84460.1 - 0.067 13.9 0.0 0.21 12.3 0.0 1.8 2 0 0 2 2 2 0 Nucleic acid-binding domain (NAR) NAPRTase PF04095.16 KII84461.1 - 5.2e-65 219.4 0.0 7.7e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KII84461.1 - 2.2e-35 121.8 0.1 3.3e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNase_PH PF01138.21 KII84462.1 - 1.5e-34 119.3 0.3 3.5e-34 118.2 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KII84462.1 - 0.004 17.2 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.17 KII84463.1 - 5.5e-55 185.5 0.0 7.1e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KII84463.1 - 0.00025 21.7 0.0 0.00055 20.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84463.1 - 0.054 14.1 0.0 0.16 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KII84463.1 - 0.058 12.9 0.0 0.56 9.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KII84463.1 - 0.071 13.9 0.0 0.21 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Citrate_synt PF00285.21 KII84464.1 - 8.3e-99 331.1 0.0 9.8e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KII84464.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone gag_pre-integrs PF13976.6 KII84467.1 - 1.6e-06 27.8 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain VitD-bind_III PF09164.10 KII84468.1 - 8.2 6.5 7.4 10 6.2 1.2 2.5 1 1 1 2 2 2 0 Vitamin D binding protein, domain III Methyltransf_23 PF13489.6 KII84471.1 - 1.2e-14 54.5 0.0 1.8e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII84471.1 - 6.7e-14 52.4 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84471.1 - 1.5e-11 44.8 0.0 3.8e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII84471.1 - 8.1e-09 35.5 0.0 6.3e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII84471.1 - 3.8e-07 30.8 0.0 1.5e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII84471.1 - 7.5e-06 25.4 0.0 4.4e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KII84471.1 - 1.1e-05 24.9 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF938 PF06080.12 KII84471.1 - 4.2e-05 23.4 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_8 PF05148.15 KII84471.1 - 0.00021 21.2 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 KII84471.1 - 0.00094 17.8 0.0 0.0044 15.6 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KII84471.1 - 0.0015 18.1 0.0 0.0093 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KII84471.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KII84471.1 - 0.028 13.9 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 KII84471.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA-synt_His PF13393.6 KII84473.1 - 0.17 11.1 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Pkinase PF00069.25 KII84474.1 - 2.2e-11 43.6 0.0 2.4e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84474.1 - 4.5e-11 42.5 0.0 5.3e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII84474.1 - 0.012 15.0 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KII84474.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KII84474.1 - 0.2 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII84474.1 - 0.24 11.0 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Pirin PF02678.16 KII84475.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.7 2 0 0 2 2 2 0 Pirin Ribonuc_red_sm PF00268.21 KII84479.1 - 2.9e-78 263.2 0.4 3.5e-78 262.9 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain HWE_HK PF07536.14 KII84479.1 - 0.016 15.9 0.9 0.033 14.9 0.7 1.6 1 1 0 1 1 1 0 HWE histidine kinase Ribonuc_red_sm PF00268.21 KII84480.1 - 1.8e-91 306.5 0.1 6.7e-91 304.6 0.1 1.7 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain Fungal_trans PF04082.18 KII84482.1 - 3.1e-19 69.1 0.3 3.7e-19 68.8 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain BUD22 PF09073.10 KII84484.1 - 0.00042 19.8 11.0 0.00056 19.4 11.0 1.1 1 0 0 1 1 1 1 BUD22 YL1 PF05764.13 KII84484.1 - 0.00082 19.6 11.1 0.0012 19.1 11.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 KII84484.1 - 0.0044 16.5 18.1 0.006 16.1 18.1 1.1 1 0 0 1 1 1 1 SDA1 PDCD2_C PF04194.13 KII84484.1 - 0.0085 16.2 0.2 0.014 15.5 0.2 1.4 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Nop14 PF04147.12 KII84484.1 - 0.032 12.5 22.0 0.041 12.1 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 KII84484.1 - 0.035 12.2 29.2 0.042 12.0 29.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 KII84484.1 - 0.088 12.2 19.3 0.11 11.8 19.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 KII84484.1 - 0.24 9.8 18.5 0.3 9.5 18.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 KII84484.1 - 0.28 9.4 14.3 0.31 9.3 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 KII84484.1 - 0.71 9.7 9.6 1.2 8.9 9.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 KII84484.1 - 0.79 8.9 1.8 0.97 8.6 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DARPP-32 PF05395.12 KII84484.1 - 3.2 7.9 14.0 6.2 7.0 14.0 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF5523 PF17661.1 KII84484.1 - 9.5 5.8 15.4 12 5.5 15.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) VitD-bind_III PF09164.10 KII84486.1 - 0.034 14.1 0.1 0.061 13.3 0.0 1.5 2 0 0 2 2 2 0 Vitamin D binding protein, domain III KDZ PF18758.1 KII84489.1 - 8.8e-51 172.7 0.0 1.6e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KII84489.1 - 2.8e-11 43.7 0.0 5.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KII84489.1 - 0.00026 21.1 0.0 0.00065 19.8 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII84489.1 - 0.0053 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases F-box-like PF12937.7 KII84490.1 - 2.6e-10 40.0 0.5 4.8e-10 39.2 0.5 1.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII84490.1 - 0.002 18.0 1.3 0.087 12.7 0.1 2.3 2 0 0 2 2 2 2 F-box domain OrsD PF12013.8 KII84491.1 - 5.6e-08 33.2 5.4 7.4e-08 32.8 0.4 2.9 2 1 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D Cas_Cas6 PF01881.16 KII84491.1 - 0.071 13.7 0.0 0.21 12.2 0.0 1.7 2 0 0 2 2 2 0 CRISPR associated protein Cas6 ATP1G1_PLM_MAT8 PF02038.16 KII84491.1 - 0.16 11.4 0.2 0.32 10.4 0.2 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF3807 PF12720.7 KII84492.1 - 9.1 6.5 9.8 5.6 7.2 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) PrkA PF06798.12 KII84493.1 - 0.049 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Retrotrans_gag PF03732.17 KII84496.1 - 0.0028 17.9 0.2 0.0045 17.2 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Rota_NS6 PF04866.12 KII84496.1 - 0.051 13.8 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 Act-Frag_cataly PF09192.10 KII84496.1 - 0.096 12.1 0.1 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic DnaA_N PF11638.8 KII84496.1 - 0.1 12.4 0.1 9 6.1 0.0 2.5 2 0 0 2 2 2 0 DnaA N-terminal domain Alpha_kinase PF02816.18 KII84498.1 - 4.1e-22 79.2 0.0 8.4e-22 78.2 0.0 1.5 2 0 0 2 2 2 1 Alpha-kinase family DIX PF00778.17 KII84498.1 - 0.067 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 DIX domain CinA_KH PF18146.1 KII84502.1 - 0.1 12.8 0.0 45 4.3 0.0 3.1 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain Plavaka PF18759.1 KII84503.1 - 3.1e-83 279.7 0.0 4.5e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase RVT_1 PF00078.27 KII84505.1 - 2e-06 27.5 0.0 5.6e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KII84505.1 - 0.11 13.2 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Plavaka PF18759.1 KII84506.1 - 2e-128 428.2 0.0 2.7e-128 427.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KII84506.1 - 0.00096 19.5 0.7 0.0039 17.6 0.7 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII84506.1 - 1.1 10.3 5.8 0.17 12.8 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SWIRM-assoc_2 PF16496.5 KII84509.1 - 0.0052 15.7 0.4 0.0052 15.7 0.4 1.6 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal Fibrinogen_C PF00147.18 KII84509.1 - 1.2 8.9 3.2 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain Plavaka PF18759.1 KII84510.1 - 4.2e-128 427.1 0.0 8e-128 426.2 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase DUF4687 PF15747.5 KII84512.1 - 0.041 14.4 1.3 0.058 13.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) SH3_9 PF14604.6 KII84513.1 - 4.1e-08 32.9 0.0 8.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII84513.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII84513.1 - 0.00041 20.0 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ammonium_transp PF00909.21 KII84515.1 - 3.8e-116 388.1 28.2 4.3e-116 387.9 28.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family F-box-like PF12937.7 KII84517.1 - 0.016 15.1 1.4 0.027 14.3 0.2 2.0 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII84518.1 - 4.4e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII84519.1 - 0.059 13.3 0.4 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII84520.1 - 0.00068 19.5 0.5 0.002 18.0 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII84520.1 - 6.4 7.4 7.0 22 5.7 0.2 3.9 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) GST_N_4 PF17172.4 KII84521.1 - 0.085 13.6 0.1 0.16 12.7 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain LRR_8 PF13855.6 KII84522.1 - 0.1 12.4 2.4 0.41 10.4 0.1 2.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KII84522.1 - 0.18 12.3 5.9 51 4.5 0.5 4.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) NOA36 PF06524.12 KII84522.1 - 3.8 6.8 5.9 6 6.1 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein Metallophos PF00149.28 KII84523.1 - 3.3e-15 57.1 0.7 7e-15 56.1 0.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AA_permease_2 PF13520.6 KII84524.1 - 4.1e-54 184.0 55.7 4.9e-54 183.8 55.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII84524.1 - 9.1e-09 34.4 49.8 1.3e-08 33.9 49.8 1.1 1 0 0 1 1 1 1 Amino acid permease O-FucT PF10250.9 KII84525.1 - 8.7e-11 42.1 0.0 2.1e-06 27.7 0.0 3.0 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase eIF3g PF12353.8 KII84526.1 - 8.4e-43 145.7 1.4 1.2e-42 145.2 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KII84526.1 - 2.5e-18 65.6 0.0 3.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KII84526.1 - 0.04 14.1 1.1 2.7 8.2 0.1 2.9 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KII84526.1 - 0.057 13.5 0.2 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif CG-1 PF03859.16 KII84529.1 - 0.097 12.5 0.5 0.15 11.9 0.1 1.7 2 1 0 2 2 2 0 CG-1 domain Asp PF00026.23 KII84530.1 - 2.8e-74 250.4 1.2 3.4e-74 250.1 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII84530.1 - 1.1e-13 51.8 0.4 1.2e-06 28.9 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII84530.1 - 3.4e-07 30.8 3.5 0.22 12.2 0.1 4.4 3 1 0 3 3 3 2 Aspartyl protease MFS_1 PF07690.16 KII84532.1 - 1.4e-42 145.9 53.2 2.7e-42 145.0 53.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII84532.1 - 1.4e-12 47.2 13.0 1.4e-12 47.2 13.0 3.0 4 0 0 4 4 4 2 Sugar (and other) transporter PCI PF01399.27 KII84533.1 - 2.2e-05 24.9 0.0 5.5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_10 PF13374.6 KII84533.1 - 0.18 11.7 1.9 0.58 10.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FMN_red PF03358.15 KII84534.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KII84534.1 - 0.0044 16.8 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold F-box-like PF12937.7 KII84536.1 - 2.5e-06 27.3 1.4 2.5e-06 27.3 1.4 2.5 3 0 0 3 3 3 1 F-box-like Abhydrolase_9 PF10081.9 KII84537.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family MFS_1 PF07690.16 KII84538.1 - 5.9e-25 87.9 33.5 5.9e-25 87.9 33.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII84538.1 - 5.5e-05 22.6 8.0 5.5e-05 22.6 8.0 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB GHMP_kinases_C PF08544.13 KII84538.1 - 0.14 12.5 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal NAD_binding_4 PF07993.12 KII84539.1 - 9.4e-39 133.1 0.0 1.3e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII84539.1 - 1.3e-30 106.4 0.0 6.5e-30 104.1 0.0 2.0 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII84539.1 - 2.3e-12 46.9 0.0 3.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KII84539.1 - 3.1e-08 33.9 0.1 6.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KII84539.1 - 0.00068 18.8 0.0 0.62 9.1 0.0 2.4 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KII84539.1 - 0.00075 19.0 0.0 0.0093 15.4 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KII84539.1 - 0.0089 16.0 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII84539.1 - 0.021 14.7 0.2 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KII84539.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KII84540.1 - 2.8e-09 36.7 1.3 8.1e-09 35.3 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII84540.1 - 0.048 13.6 5.8 0.19 11.6 1.6 3.1 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KII84541.1 - 3.2e-09 36.5 0.8 3.2e-09 36.5 0.8 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII84541.1 - 0.00044 20.0 3.9 0.067 13.1 0.4 4.2 3 1 0 3 3 3 2 F-box domain LRR_4 PF12799.7 KII84541.1 - 0.016 15.7 0.1 13 6.4 0.0 3.7 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) PGI PF00342.19 KII84543.1 - 2.3e-232 771.9 0.3 2.6e-232 771.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ras PF00071.22 KII84544.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Ras family Tri3 PF07428.11 KII84546.1 - 8.7e-05 21.6 0.0 0.00011 21.3 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Aldose_epim PF01263.20 KII84547.1 - 3e-59 200.8 0.3 4.5e-59 200.2 0.3 1.2 1 1 0 1 1 1 1 Aldose 1-epimerase Gln-synt_C PF00120.24 KII84548.1 - 1.1e-68 231.8 0.0 1.8e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KII84548.1 - 0.0021 17.9 0.0 0.0089 15.8 0.0 2.1 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Sigma70_r1_1 PF03979.14 KII84548.1 - 0.098 12.7 0.0 2.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 Glu_cys_ligase PF04262.14 KII84548.1 - 0.2 10.3 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase adh_short PF00106.25 KII84549.1 - 2.6e-29 102.1 0.1 8.1e-25 87.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII84549.1 - 3.7e-17 62.7 0.1 1.5e-14 54.2 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII84549.1 - 3.1e-09 37.0 0.1 4.7e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII84549.1 - 0.00079 19.0 0.1 0.0013 18.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII84549.1 - 0.0097 15.3 0.0 0.02 14.3 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sec39 PF08314.11 KII84549.1 - 0.036 12.5 0.1 0.054 11.9 0.1 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Polysacc_synt_2 PF02719.15 KII84549.1 - 0.089 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KII84549.1 - 0.12 12.2 0.5 0.23 11.3 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding RRM_1 PF00076.22 KII84553.1 - 6e-20 70.8 0.0 7.3e-12 44.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII84553.1 - 0.15 12.2 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif NAD_binding_4 PF07993.12 KII84556.1 - 1.2e-31 109.8 0.0 1.9e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII84556.1 - 6.4e-22 77.7 0.0 4.9e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KII84556.1 - 4.3e-09 36.2 0.0 9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII84556.1 - 0.00058 19.8 0.0 0.0035 17.3 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KII84556.1 - 0.003 17.5 0.0 0.011 15.7 0.0 2.0 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 KII84556.1 - 0.0042 17.4 0.2 0.022 15.1 0.2 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site BTB PF00651.31 KII84559.1 - 6.9e-06 26.3 0.0 2.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain COesterase PF00135.28 KII84560.1 - 1.8e-77 261.4 0.0 2.3e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII84560.1 - 7.6e-06 25.9 1.5 3.3e-05 23.8 1.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Oxidored-like PF09791.9 KII84561.1 - 1.1e-19 69.9 0.4 2.1e-19 68.9 0.4 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal CSN5_C PF18323.1 KII84562.1 - 1.3e-31 109.3 5.1 2.6e-31 108.4 5.1 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 KII84562.1 - 2.6e-29 101.6 0.1 4.9e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KII84562.1 - 0.00034 20.4 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.6 KII84562.1 - 0.14 12.8 1.7 0.27 11.9 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) UPF0172 PF03665.13 KII84562.1 - 0.15 12.1 1.9 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Metallophos PF00149.28 KII84564.1 - 9.6e-13 49.1 2.2 1.4e-12 48.6 1.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase adh_short PF00106.25 KII84565.1 - 3.4e-24 85.4 0.4 4.6e-24 84.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII84565.1 - 1.3e-18 67.4 2.2 1.6e-18 67.1 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII84565.1 - 7.3e-05 22.8 0.1 9.8e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII84565.1 - 0.0027 17.6 2.1 0.0045 16.9 2.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding AA_permease_2 PF13520.6 KII84566.1 - 4.8e-73 246.4 36.7 6.3e-73 246.0 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII84566.1 - 4.6e-15 55.2 31.4 6.2e-15 54.7 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KII84567.1 - 3e-07 30.2 1.3 8.5e-07 28.8 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII84567.1 - 0.0055 16.6 0.1 0.023 14.6 0.1 2.1 1 0 0 1 1 1 1 F-box domain p450 PF00067.22 KII84568.1 - 3.4e-82 276.6 0.0 4.1e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KII84570.1 - 2.5e-10 40.1 0.1 5.2e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII84570.1 - 0.00014 21.6 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII84571.1 - 6.9e-10 38.7 0.1 1.3e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII84571.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Pro_isomerase PF00160.21 KII84573.1 - 4.1e-46 157.1 1.1 4.6e-46 157.0 1.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.22 KII84574.1 - 8.6e-77 258.8 0.0 9.6e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2560 PF10834.8 KII84574.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) Peptidase_C48 PF02902.19 KII84575.1 - 8.9e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Antimicrobial_6 PF08036.11 KII84575.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Diapausin family of antimicrobial peptide KDZ PF18758.1 KII84578.1 - 0.0005 19.8 0.8 0.0005 19.7 0.8 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 KII84579.1 - 3.1e-45 153.2 2.1 8.7e-45 151.8 2.1 1.7 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII84579.1 - 7.7e-05 22.4 1.0 0.00014 21.6 1.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase zf-RING_5 PF14634.6 KII84579.1 - 0.6 10.1 6.1 1.1 9.2 0.3 3.4 3 0 0 3 3 3 0 zinc-RING finger domain p450 PF00067.22 KII84582.1 - 2.4e-81 273.8 0.0 2.9e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Citrate_bind PF16114.5 KII84583.1 - 4.1e-89 296.8 0.0 8.7e-89 295.7 0.0 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KII84583.1 - 6.3e-20 71.6 0.1 2.7e-17 62.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KII84583.1 - 1.1e-14 54.5 0.1 5e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 KII84583.1 - 3.2e-12 47.0 0.0 7.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 KII84583.1 - 1.5e-05 24.8 0.0 8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 KII84583.1 - 2.4e-05 24.0 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ribonucleas_3_3 PF14622.6 KII84584.1 - 8.8e-18 64.7 0.0 6.6e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII84584.1 - 0.015 15.9 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain Rad60-SLD_2 PF13881.6 KII84586.1 - 7.1e-14 51.9 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KII84586.1 - 0.0012 18.6 0.0 0.0081 15.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family Ribosomal_L18A PF01775.17 KII84587.1 - 4.3e-55 185.0 0.3 5.2e-55 184.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Lactonase PF10282.9 KII84588.1 - 2.2e-44 152.2 0.0 2.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF2264 PF10022.9 KII84589.1 - 1.3e-140 468.6 0.2 1.5e-140 468.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) p450 PF00067.22 KII84590.1 - 5.7e-80 269.3 0.0 6.8e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SAPS PF04499.15 KII84590.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein p450 PF00067.22 KII84593.1 - 5.9e-83 279.2 0.0 7.2e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1275 PF06912.11 KII84596.1 - 2.9e-31 108.9 18.7 3.6e-31 108.6 18.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KII84596.1 - 3.2 6.6 28.4 2.1 7.2 15.7 2.6 2 1 0 2 2 2 0 Major Facilitator Superfamily p450 PF00067.22 KII84597.1 - 4e-66 223.7 0.0 5e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII84599.1 - 1e-68 232.2 0.0 1.4e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4632 PF15451.6 KII84599.1 - 0.21 11.7 0.2 0.54 10.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) p450 PF00067.22 KII84600.1 - 3.6e-26 91.9 0.0 4.2e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 pEK499_p136 PF18736.1 KII84600.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.4 1 1 0 1 1 1 0 HEPN pEK499 p136 TBSV_P22 PF03558.13 KII84600.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 TBSV core protein P21/P22 DUF2627 PF11118.8 KII84601.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) APH PF01636.23 KII84602.1 - 3.6e-13 50.0 0.0 4.3e-12 46.5 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KII84602.1 - 0.25 10.2 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Amidase PF01425.21 KII84603.1 - 2.3e-92 310.3 0.0 2.9e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Amidase HCV_NS1 PF01560.17 KII84606.1 - 0.011 14.5 0.1 0.011 14.5 0.1 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 PTS_EIIB PF00367.20 KII84606.1 - 0.044 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 phosphotransferase system, EIIB Amidase PF01425.21 KII84608.1 - 1.3e-61 208.9 0.1 1.6e-61 208.6 0.1 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 KII84612.1 - 2.6e-61 208.0 0.1 3e-61 207.8 0.1 1.0 1 0 0 1 1 1 1 Amidase HCV_NS5a_C PF12941.7 KII84613.1 - 0.024 14.5 3.2 0.054 13.3 3.2 1.6 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region SGS PF05002.15 KII84613.1 - 0.026 14.6 0.2 0.052 13.7 0.2 1.5 1 0 0 1 1 1 0 SGS domain RPA_interact_N PF14766.6 KII84613.1 - 0.55 9.9 10.8 0.16 11.6 4.1 2.4 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Mob1_phocein PF03637.17 KII84614.1 - 1.7e-25 90.0 0.0 2.7e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.25 KII84615.1 - 7.4e-40 137.0 0.0 4.4e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII84615.1 - 2.8e-23 82.5 0.0 3.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII84615.1 - 3.8e-07 29.2 0.0 5.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII84615.1 - 0.0082 16.1 1.4 0.028 14.3 1.4 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII84615.1 - 0.17 11.2 0.0 0.79 9.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRP-L20 PF12824.7 KII84615.1 - 7.3 6.7 6.2 2.2 8.4 3.0 1.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 TFIIA_gamma_N PF02268.16 KII84616.1 - 3.3e-25 87.8 0.1 5e-25 87.3 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KII84616.1 - 1.3e-21 76.4 0.1 2.1e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit F-box-like PF12937.7 KII84617.1 - 8.2e-05 22.4 0.8 8.2e-05 22.4 0.8 2.1 2 0 0 2 2 2 1 F-box-like DUF4164 PF13747.6 KII84617.1 - 0.0034 17.6 0.8 0.0063 16.8 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Filament PF00038.21 KII84617.1 - 0.0051 16.4 0.5 0.0075 15.9 0.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein Flagellin_N PF00669.20 KII84617.1 - 0.054 13.6 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Spc7 PF08317.11 KII84617.1 - 0.071 12.0 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Dad2 PF08654.10 KII84617.1 - 0.087 13.3 0.3 0.18 12.3 0.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF1664 PF07889.12 KII84617.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 KII84617.1 - 0.13 12.5 2.4 0.49 10.7 2.4 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain CEP63 PF17045.5 KII84617.1 - 0.22 11.4 0.6 0.33 10.8 0.6 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa F-box PF00646.33 KII84617.1 - 0.38 10.7 1.5 7.5 6.6 0.3 2.7 2 0 0 2 2 2 0 F-box domain Kinetochor_Ybp2 PF08568.10 KII84620.1 - 6.1e-14 51.4 0.0 1.2e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin MMS19_C PF12460.8 KII84620.1 - 0.0019 17.4 0.1 0.016 14.4 0.1 2.2 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal ABM PF03992.16 KII84621.1 - 7.3e-07 29.2 0.0 0.0056 16.8 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KII84621.1 - 0.0009 19.4 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4937 Dus PF01207.17 KII84622.1 - 9.6e-54 182.6 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KII84622.1 - 0.04 12.9 0.1 0.065 12.2 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KII84622.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ABM PF03992.16 KII84623.1 - 2.5e-06 27.5 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DIOX_N PF14226.6 KII84624.1 - 4.7e-20 72.5 0.0 9.5e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII84624.1 - 2.7e-10 40.7 0.0 4.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KII84625.1 - 3.9e-33 114.8 35.9 1.9e-32 112.5 34.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KII84625.1 - 0.1 12.3 1.3 0.23 11.2 1.3 1.6 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain NAD4L PF06235.11 KII84628.1 - 8.2 6.5 13.9 1.2 9.2 5.5 2.4 2 0 0 2 2 2 0 NADH dehydrogenase subunit 4L (NAD4L) R3H PF01424.22 KII84629.1 - 6.4e-15 54.9 0.2 2.1e-14 53.2 0.3 1.8 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 KII84629.1 - 1.3e-05 25.2 14.3 1.3e-05 25.2 14.3 13.9 14 1 0 14 14 14 8 NF-X1 type zinc finger GST_N_3 PF13417.6 KII84631.1 - 1.7e-06 28.4 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII84631.1 - 0.00015 21.7 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KII84631.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII84631.1 - 0.066 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.21 KII84633.1 - 2.5e-91 306.9 0.0 3.2e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Spore_coat_CotO PF14153.6 KII84633.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SET PF00856.28 KII84634.1 - 1.8e-14 54.5 0.0 3.3e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KII84634.1 - 4.8e-10 39.4 10.2 4.8e-10 39.4 10.2 2.9 2 1 1 3 3 3 1 MYND finger Peroxin-13_N PF04088.13 KII84635.1 - 1.7e-42 145.2 0.0 2.7e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KII84635.1 - 1.9e-11 43.4 1.4 2.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KII84635.1 - 2.6e-11 43.0 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII84635.1 - 4.3e-07 29.7 0.5 9.8e-07 28.5 0.5 1.6 1 1 0 1 1 1 1 Variant SH3 domain Med26_M PF15694.5 KII84637.1 - 0.029 14.4 9.2 0.032 14.3 9.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain CotH PF08757.11 KII84637.1 - 0.071 12.6 0.0 0.072 12.6 0.0 1.0 1 0 0 1 1 1 0 CotH kinase protein Med3 PF11593.8 KII84637.1 - 0.12 11.6 10.7 0.14 11.3 10.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.9 KII84637.1 - 1.2 8.7 19.6 1.4 8.5 19.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 KII84637.1 - 1.8 8.2 7.4 2.1 8.0 7.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CH PF00307.31 KII84639.1 - 7.3e-76 251.4 0.0 3.4e-19 69.0 0.0 4.5 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KII84639.1 - 4.6e-07 29.6 0.0 3.8 7.4 0.0 4.5 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_7 PF13499.6 KII84639.1 - 0.0074 16.7 0.0 0.041 14.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair Pkinase PF00069.25 KII84640.1 - 1.4e-27 96.7 0.0 1.2e-25 90.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84640.1 - 2.9e-21 75.9 0.0 4.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 KII84640.1 - 4.9e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Plk4_PB2 PF18409.1 KII84640.1 - 8.7e-05 23.2 0.0 0.00032 21.4 0.0 2.0 2 0 0 2 2 2 1 Polo-like Kinase 4 Polo Box 2 Kinase-like PF14531.6 KII84640.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glft2_N PF17994.1 KII84640.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Galactofuranosyltransferase 2 N-terminal PDDEXK_3 PF13366.6 KII84640.1 - 0.18 12.2 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Tyrosinase PF00264.20 KII84641.1 - 2.7e-32 112.9 7.7 4.3e-32 112.2 7.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase NIR_SIR PF01077.22 KII84642.1 - 0.048 13.2 0.0 4.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain Phage_GPA PF05840.13 KII84642.1 - 0.085 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) IFRD PF05004.13 KII84643.1 - 0.049 12.7 1.1 0.05 12.7 1.1 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) GST_N_3 PF13417.6 KII84647.1 - 5.9e-06 26.6 0.1 1.2e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII84647.1 - 1.7e-05 25.0 0.1 3.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII84647.1 - 0.00032 20.7 0.2 0.00052 20.0 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KII84647.1 - 0.0035 17.7 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Bestrophin PF01062.21 KII84648.1 - 5.7e-38 131.0 2.0 1.5e-20 73.8 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel UBM PF14377.6 KII84651.1 - 0.017 14.5 5.5 1.8 8.1 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin binding region BBE PF08031.12 KII84651.1 - 0.21 11.7 4.1 20 5.4 0.4 3.2 3 0 0 3 3 3 0 Berberine and berberine like WW PF00397.26 KII84655.1 - 0.00061 19.8 0.5 0.021 14.9 0.1 2.6 2 0 0 2 2 2 1 WW domain Imm68 PF15583.6 KII84655.1 - 0.14 12.3 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 68 Pmp3 PF01679.17 KII84658.1 - 1.2e-19 70.2 4.0 2e-13 50.3 0.3 2.1 2 0 0 2 2 2 2 Proteolipid membrane potential modulator Phage_GPA PF05840.13 KII84661.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Tyrosinase PF00264.20 KII84662.1 - 2.6e-32 112.9 7.7 4.3e-32 112.2 7.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 KII84664.1 - 2.6e-32 112.1 41.6 2.6e-32 112.1 41.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KII84664.1 - 0.00065 18.1 5.7 0.0055 15.0 5.6 2.1 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DCP1 PF06058.13 KII84666.1 - 1.5e-24 86.1 0.0 4.8e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Dcp1-like decapping family PRP3 PF08572.10 KII84667.1 - 3.1e-72 242.9 2.2 5.8e-72 242.1 2.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KII84667.1 - 7.1e-45 152.7 1.3 1e-44 152.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.18 KII84668.1 - 2.6e-37 127.8 0.1 3.1e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pyridoxal_deC PF00282.19 KII84669.1 - 4.8e-61 206.5 0.0 6.9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Retrotran_gag_2 PF14223.6 KII84670.1 - 2.6e-15 56.3 0.0 3.3e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII84670.1 - 0.0076 16.3 3.6 0.013 15.5 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Pyridoxal_deC PF00282.19 KII84671.1 - 1.9e-54 184.8 0.0 2.7e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Bac_surface_Ag PF01103.23 KII84672.1 - 2.2e-38 132.5 0.6 2.8e-38 132.2 0.6 1.1 1 0 0 1 1 1 1 Surface antigen MatE PF01554.18 KII84673.1 - 1.2e-51 174.5 25.4 1.1e-26 93.4 7.8 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KII84673.1 - 1.5e-05 25.1 9.8 1.5e-05 25.1 9.8 3.9 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 KII84674.1 - 1.7e-26 93.0 34.4 2.5e-26 92.4 34.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KII84675.1 - 1.5e-25 89.9 33.7 2.2e-25 89.3 33.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S8 PF00410.19 KII84676.1 - 1.7e-08 34.5 0.0 7.2e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 Mucin15 PF15672.5 KII84677.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 ABC2_membrane_3 PF12698.7 KII84677.1 - 0.31 10.1 6.2 0.26 10.3 1.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Tri3 PF07428.11 KII84678.1 - 0.00067 18.7 0.0 0.002 17.1 0.0 1.7 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Alpha-L-AF_C PF06964.12 KII84680.1 - 1.5e-36 126.1 0.5 6.3e-36 124.0 0.1 2.0 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KII84680.1 - 0.00025 21.3 0.8 0.00071 19.9 0.8 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain CBM_6 PF03422.15 KII84680.1 - 0.14 12.4 4.1 0.47 10.7 3.3 2.3 1 1 0 1 1 1 0 Carbohydrate binding module (family 6) Hist_deacetyl PF00850.19 KII84681.1 - 1.1e-57 195.9 0.0 1.5e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain TAL_FSA PF00923.19 KII84682.1 - 8.3e-47 159.9 0.2 1e-46 159.6 0.2 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Flot PF15975.5 KII84682.1 - 0.032 14.4 0.5 0.088 13.0 0.5 1.7 1 0 0 1 1 1 0 Flotillin UPF0444 PF15475.6 KII84682.1 - 0.056 13.7 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 EspB_PE PF18625.1 KII84682.1 - 0.15 12.6 2.2 0.93 10.0 2.0 2.3 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain CRIM PF16978.5 KII84683.1 - 8e-44 149.2 0.0 2.1e-43 147.9 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KII84683.1 - 1.8e-31 108.7 1.4 2.7e-31 108.1 1.4 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 KII84683.1 - 1.4e-07 31.5 0.0 4.4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 KII84683.1 - 0.00057 20.1 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 TUG ubiquitin-like domain DDE_3 PF13358.6 KII84685.1 - 9.4e-05 22.2 0.3 0.0001 22.1 0.3 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Nucleoporin_FG2 PF15967.5 KII84687.1 - 0.45 9.0 1.9 0.51 8.8 1.9 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region RraB PF06877.11 KII84690.1 - 0.16 12.7 0.0 0.19 12.5 0.0 1.2 1 0 0 1 1 1 0 Regulator of ribonuclease activity B WXG100 PF06013.12 KII84691.1 - 0.0025 18.0 33.1 0.29 11.4 3.5 5.1 4 1 0 4 4 4 3 Proteins of 100 residues with WXG DUF4116 PF13475.6 KII84691.1 - 0.022 14.5 1.3 1.3e+02 2.4 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) TMF_TATA_bd PF12325.8 KII84691.1 - 0.052 13.8 34.7 0.94 9.7 6.7 4.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KII84691.1 - 1 9.4 39.0 2.9 7.9 3.0 3.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Chibby PF14645.6 KII84691.1 - 1.1 9.7 16.8 0.93 9.9 0.2 4.2 1 1 2 4 4 4 0 Chibby family SKA2 PF16740.5 KII84691.1 - 1.8 8.4 36.7 9 6.1 1.0 4.8 2 1 2 5 5 5 0 Spindle and kinetochore-associated protein 2 DUF4686 PF15742.5 KII84691.1 - 2.9 6.9 45.3 0.36 9.9 22.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Methyltransf_25 PF13649.6 KII84691.1 - 3.3 8.5 5.5 45 4.8 0.3 3.5 1 1 1 3 3 3 0 Methyltransferase domain ABC_tran_CTD PF16326.5 KII84691.1 - 3.6 7.9 37.9 7.3 6.9 3.4 5.6 2 1 4 6 6 6 0 ABC transporter C-terminal domain DUF1664 PF07889.12 KII84691.1 - 4.3 7.4 21.6 9.6 6.3 3.1 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FAM184 PF15665.5 KII84691.1 - 5.9 6.6 40.2 2.3 8.0 6.9 3.2 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B FapA PF03961.13 KII84691.1 - 8.1 4.9 30.8 2 7.0 11.1 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A SR-25 PF10500.9 KII84695.1 - 0.00096 18.8 1.7 0.0012 18.5 1.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Retrotran_gag_2 PF14223.6 KII84696.1 - 1.8e-09 37.4 0.0 2.2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KII84697.1 - 1.6e-16 60.3 0.1 3.2e-16 59.3 0.0 1.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Integrase_H2C2 PF17921.1 KII84698.1 - 2.5e-06 27.5 0.1 5.7e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain IPP-2 PF04979.14 KII84698.1 - 0.01 16.5 2.7 0.045 14.5 2.8 1.9 1 1 1 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) KDZ PF18758.1 KII84699.1 - 2.3e-63 213.8 0.0 3.7e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII84699.1 - 5.7e-10 39.3 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII84699.1 - 4.2e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CAC1F_C PF16885.5 KII84702.1 - 2.5 7.7 3.9 3.7 7.1 3.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Herpes_ORF11 PF04797.13 KII84705.1 - 0.0048 15.8 0.0 0.0067 15.3 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus dUTPase protein gag-asp_proteas PF13975.6 KII84705.1 - 0.0082 16.7 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KII84709.1 - 0.038 14.1 3.0 0.072 13.2 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KII84709.1 - 3.8 7.3 7.4 1.8 8.3 3.8 2.3 2 1 0 2 2 2 0 GAG-polyprotein viral zinc-finger SpoIIE PF07228.12 KII84710.1 - 0.00026 21.0 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KII84710.1 - 0.0048 16.6 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SPX PF03105.19 KII84710.1 - 0.037 13.9 0.2 0.037 13.9 0.2 2.7 1 1 1 3 3 3 0 SPX domain PP2C_2 PF13672.6 KII84710.1 - 0.074 12.7 0.3 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C Aldedh PF00171.22 KII84711.1 - 2.8e-119 398.7 0.0 3.1e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KII84711.1 - 9.2e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SWIRM-assoc_3 PF16498.5 KII84711.1 - 0.074 13.3 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal BAR_2 PF10455.9 KII84712.1 - 2.8e-48 164.5 0.2 7.6e-48 163.1 0.2 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KII84712.1 - 1.1e-15 57.9 0.6 9.1e-15 55.0 0.6 1.9 1 1 0 1 1 1 1 BAR domain Proteasome PF00227.26 KII84713.1 - 2.9e-48 163.9 0.1 3.5e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KII84713.1 - 4.9e-10 38.6 1.2 4.9e-10 38.6 1.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal EMP24_GP25L PF01105.24 KII84714.1 - 4.7e-42 144.0 0.0 5.4e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.11 KII84714.1 - 0.12 12.5 1.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Glyco_trans_1_2 PF13524.6 KII84714.1 - 0.13 12.7 0.1 6.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ribosomal_S10 PF00338.22 KII84715.1 - 2.8e-27 94.8 0.2 4.1e-27 94.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Phage_RpbA PF10789.9 KII84715.1 - 0.097 12.7 0.8 0.15 12.1 0.8 1.4 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA EnY2 PF10163.9 KII84716.1 - 6.4e-24 84.1 0.2 7.4e-24 83.9 0.2 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 RACo_linker PF17650.1 KII84716.1 - 0.13 12.1 1.8 5.6 6.9 0.2 2.1 1 1 0 2 2 2 0 RACo linker region Mago_nashi PF02792.14 KII84717.1 - 2e-72 241.9 0.2 2.2e-72 241.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Pkinase PF00069.25 KII84719.1 - 8.8e-23 81.0 0.0 1.1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84719.1 - 9e-11 41.5 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII84719.1 - 3.1e-08 32.8 0.4 4e-08 32.4 0.4 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII84719.1 - 0.054 13.4 0.1 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family MRG PF05712.13 KII84721.1 - 1.2e-50 171.6 0.0 1.6e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KII84721.1 - 2e-10 40.4 0.4 3.6e-10 39.6 0.4 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KII84721.1 - 0.042 13.8 1.4 0.082 12.8 1.4 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Redoxin PF08534.10 KII84722.1 - 5.9e-29 100.7 0.0 7.1e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KII84722.1 - 4.3e-11 42.8 0.0 5.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII84723.1 - 1.9e-29 102.3 0.0 2.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KII84723.1 - 3.2e-11 43.2 0.0 4.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TMEM154 PF15102.6 KII84724.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF2207 PF09972.9 KII84724.1 - 0.032 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Neurensin PF14927.6 KII84724.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Neurensin HA2 PF04408.23 KII84726.1 - 4.3e-24 84.9 0.0 8.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KII84726.1 - 2.5e-21 75.8 0.0 6.8e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KII84726.1 - 3.1e-10 40.4 0.0 2.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII84726.1 - 3.7e-08 33.3 0.3 1.3e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SRP54 PF00448.22 KII84726.1 - 9.6e-05 22.1 0.2 0.0003 20.5 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KII84726.1 - 0.00012 22.3 0.0 0.00047 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII84726.1 - 0.00019 21.8 0.3 0.00047 20.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII84726.1 - 0.004 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KII84726.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KII84726.1 - 0.013 15.4 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KII84726.1 - 0.019 15.0 0.1 5.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KII84726.1 - 0.083 12.3 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 KII84726.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KII84726.1 - 0.095 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 KII84726.1 - 0.099 12.0 0.9 0.57 9.5 0.1 2.4 3 1 0 3 3 3 0 KaiC AAA_7 PF12775.7 KII84726.1 - 0.12 11.9 0.1 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region HTH_IclR PF09339.10 KII84726.1 - 0.24 11.2 0.9 0.79 9.6 0.1 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain Proteasome PF00227.26 KII84727.1 - 3.7e-29 101.6 0.1 4.5e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.17 KII84727.1 - 0.0022 17.8 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family, helical bundle domain O-FucT PF10250.9 KII84728.1 - 1.5e-11 44.6 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DnaJ-X PF14308.6 KII84729.1 - 7.9e-53 179.0 0.4 7.9e-53 179.0 0.4 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KII84729.1 - 2.4e-25 88.4 0.9 2.4e-25 88.4 0.9 2.3 3 0 0 3 3 3 1 DnaJ domain Nup_retrotrp_bd PF10599.9 KII84729.1 - 0.012 16.3 0.3 0.021 15.4 0.3 1.4 1 0 0 1 1 1 0 Retro-transposon transporting motif zinc_ribbon_4 PF13717.6 KII84729.1 - 0.13 12.2 1.0 0.36 10.8 1.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain tRNA-synt_1b PF00579.25 KII84730.1 - 8e-57 192.8 0.0 4.7e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) FtsJ PF01728.19 KII84731.1 - 3.8e-41 141.1 0.0 8.5e-41 140.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase APH PF01636.23 KII84732.1 - 1.9e-16 60.7 0.3 2.7e-16 60.2 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII84732.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DinB_2 PF12867.7 KII84733.1 - 0.008 16.7 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 DinB superfamily APH PF01636.23 KII84734.1 - 1.9e-16 60.7 1.1 5.4e-16 59.2 1.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII84734.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KII84734.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KII84734.1 - 0.12 11.9 0.0 0.6 9.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DinB_2 PF12867.7 KII84735.1 - 0.0023 18.5 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 DinB superfamily APH PF01636.23 KII84736.1 - 7.5e-17 62.1 0.0 1.2e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII84736.1 - 0.00028 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PyocinActivator PF11112.8 KII84737.1 - 0.048 13.8 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Pyocin activator protein PrtN PhzC-PhzF PF02567.16 KII84738.1 - 2.2e-35 122.5 0.0 2.6e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KII84738.1 - 0.0072 15.4 0.0 0.062 12.3 0.0 1.9 2 0 0 2 2 2 1 Proline racemase Septin PF00735.18 KII84739.1 - 2.5e-111 371.5 0.2 3.6e-111 370.9 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KII84739.1 - 5e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII84739.1 - 4.1e-07 30.1 0.1 3.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KII84739.1 - 8.6e-06 25.4 1.7 0.00056 19.5 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KII84739.1 - 0.00027 21.2 0.9 0.0015 18.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII84739.1 - 0.00036 21.0 0.2 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KII84739.1 - 0.00041 20.5 0.1 0.00093 19.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KII84739.1 - 0.0011 18.4 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 KII84739.1 - 0.0016 18.2 0.2 0.11 12.2 0.2 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KII84739.1 - 0.0031 17.1 0.3 0.013 15.2 0.3 2.0 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.27 KII84739.1 - 0.0082 16.7 0.1 0.025 15.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KII84739.1 - 0.009 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KII84739.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KII84739.1 - 0.016 15.0 0.3 0.036 13.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KII84739.1 - 0.033 14.2 0.5 0.088 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KII84739.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Casc1_N PF15927.5 KII84739.1 - 0.057 13.1 7.7 0.18 11.5 7.7 1.8 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus GPW_gp25 PF04965.14 KII84739.1 - 0.074 12.8 1.6 2.2 8.1 0.3 2.5 2 0 0 2 2 2 0 Gene 25-like lysozyme FOXP-CC PF16159.5 KII84739.1 - 0.08 13.6 0.7 0.24 12.1 0.7 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain FeoB_N PF02421.18 KII84739.1 - 0.11 12.1 0.1 0.31 10.5 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Sigma54_activat PF00158.26 KII84739.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 KII84739.1 - 0.16 12.4 1.8 1.2 9.5 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KII84739.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KII84739.1 - 0.23 11.3 3.1 3.1 7.6 0.5 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 KII84739.1 - 0.24 11.8 0.4 0.91 9.9 0.0 2.2 2 1 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 KII84739.1 - 0.36 10.9 7.5 3.1 7.8 0.1 3.0 2 1 1 3 3 3 0 Dynamin family TFIIIC_sub6 PF10419.9 KII84740.1 - 4.1e-19 68.2 0.0 7.4e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain PAPA-1 PF04795.12 KII84740.1 - 0.021 15.6 3.6 0.033 15.0 3.4 1.5 1 1 0 1 1 1 0 PAPA-1-like conserved region Arginase PF00491.21 KII84740.1 - 0.033 13.7 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Arginase family SET PF00856.28 KII84741.1 - 5.3e-09 36.7 0.2 2.1e-07 31.5 0.2 2.4 1 1 0 1 1 1 1 SET domain Noelin-1 PF12308.8 KII84741.1 - 0.018 15.0 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein BNR_4 PF15892.5 KII84742.1 - 2.1e-66 224.1 3.6 2.8e-66 223.7 3.6 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member DUF3433 PF11915.8 KII84743.1 - 6.9e-21 74.5 2.5 6.9e-21 74.5 2.5 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3433) Hydrophobin PF01185.18 KII84744.1 - 8.2e-23 80.8 10.3 9.5e-23 80.6 10.3 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Tubulin PF00091.25 KII84745.1 - 9.7e-68 228.2 0.0 2.1e-67 227.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KII84745.1 - 6.3e-42 142.7 0.1 9.9e-42 142.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KII84745.1 - 2.3e-06 27.9 0.1 6.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KII84745.1 - 0.00097 18.4 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KII84745.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain SLD5_C PF16922.5 KII84746.1 - 3.4e-08 33.6 0.0 6.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KII84746.1 - 0.00018 21.9 0.2 0.0003 21.2 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3433 PF11915.8 KII84748.1 - 1.2e-20 73.7 3.5 1.2e-20 73.7 3.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) 7TM_GPCR_Srb PF02175.16 KII84748.1 - 0.086 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb CPSase_L_D2 PF02786.17 KII84749.1 - 3.1e-116 386.3 0.6 3.3e-84 281.6 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KII84749.1 - 7.4e-50 168.1 0.0 3.5e-49 165.9 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KII84749.1 - 5.2e-46 156.8 0.0 3.2e-44 151.0 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KII84749.1 - 7.4e-45 152.6 0.0 1.6e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KII84749.1 - 2.7e-42 144.0 0.3 8.8e-41 139.1 0.0 2.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KII84749.1 - 3.7e-32 111.6 0.0 8.9e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KII84749.1 - 1.3e-18 67.3 0.3 1.7e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KII84749.1 - 3.3e-18 65.6 0.0 1.6e-17 63.4 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KII84749.1 - 3.9e-17 62.4 0.2 7.3e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KII84749.1 - 8.5e-10 38.5 0.1 0.00038 20.2 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KII84749.1 - 5e-05 23.2 0.1 0.0046 16.7 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 KII84749.1 - 8.1e-05 22.7 0.1 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KII84749.1 - 8.2e-05 22.5 0.1 0.046 13.5 0.0 4.5 5 0 0 5 5 5 1 DJ-1/PfpI family RimK PF08443.11 KII84749.1 - 0.0056 16.3 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 KII84749.1 - 0.058 13.2 0.1 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KII84749.1 - 0.11 12.0 0.0 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 ATP-grasp domain SLATT_fungal PF18142.1 KII84750.1 - 3.5e-41 139.9 0.0 4.6e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Npa1 PF11707.8 KII84750.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DUF4231 PF14015.6 KII84750.1 - 0.05 14.1 0.4 0.078 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) CBFD_NFYB_HMF PF00808.23 KII84751.1 - 1.6e-16 60.3 1.3 2.9e-16 59.5 1.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII84751.1 - 4.6e-05 23.8 0.3 4.6e-05 23.8 0.3 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5427 PF10310.9 KII84751.1 - 0.019 14.0 2.2 0.025 13.6 2.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TAFII28 PF04719.14 KII84751.1 - 0.1 12.7 1.5 0.18 11.9 1.5 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Pox_Ag35 PF03286.14 KII84751.1 - 1.3 8.7 8.8 0.25 11.1 5.2 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAD_binding_4 PF01565.23 KII84753.1 - 1.2e-18 67.2 1.6 1.9e-18 66.5 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain TAFII28 PF04719.14 KII84754.1 - 7.6e-30 102.9 0.0 1.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KII84754.1 - 0.017 15.4 0.1 0.029 14.7 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2_2 PF13465.6 KII84755.1 - 1.9e-09 37.5 6.8 2.2e-08 34.2 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KII84755.1 - 5e-08 33.0 13.0 3e-06 27.4 0.6 4.2 3 1 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KII84755.1 - 3.5e-05 24.3 8.8 0.096 13.3 0.1 3.2 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KII84755.1 - 0.0053 17.0 0.7 0.015 15.6 0.7 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KII84755.1 - 0.0083 16.5 0.2 5 7.6 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII84755.1 - 0.026 15.3 0.5 0.026 15.3 0.5 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger DUF1644 PF07800.12 KII84755.1 - 0.026 14.6 0.5 0.077 13.1 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C2H2_6 PF13912.6 KII84755.1 - 0.076 13.0 0.2 0.076 13.0 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger OrsD PF12013.8 KII84755.1 - 0.09 13.2 1.5 13 6.3 0.0 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1382 PF07131.11 KII84756.1 - 0.19 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) DUF3433 PF11915.8 KII84757.1 - 5.6e-19 68.4 4.6 5.6e-19 68.4 4.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF2951 PF11166.8 KII84758.1 - 0.092 13.0 0.1 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) CD20 PF04103.15 KII84761.1 - 3 7.9 11.1 0.15 12.2 5.2 1.7 2 0 0 2 2 2 0 CD20-like family zf-C2H2_aberr PF17017.5 KII84762.1 - 0.0038 17.4 3.3 1.3 9.1 0.6 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KII84762.1 - 0.0052 17.2 8.3 0.036 14.5 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII84762.1 - 0.062 14.2 12.0 1.6 9.8 0.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger EamA PF00892.20 KII84765.1 - 1.8e-23 83.2 29.2 2.2e-12 47.3 8.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family TMEM72 PF16054.5 KII84765.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Transmembrane protein family 72 Gemini_AC4_5_2 PF08464.10 KII84765.1 - 0.011 15.7 0.9 1.4 8.9 0.1 3.0 3 0 0 3 3 3 0 Geminivirus AC4/5 conserved region DUF2637 PF10935.8 KII84765.1 - 0.028 14.3 4.8 0.54 10.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DUF2070 PF09843.9 KII84765.1 - 0.86 7.8 16.2 0.23 9.7 6.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) ATP19 PF11022.8 KII84765.1 - 6.6 7.2 5.8 8.9 6.8 0.1 3.2 3 0 0 3 3 3 0 ATP synthase subunit K DUF2353 PF09789.9 KII84767.1 - 0.063 12.6 0.7 0.082 12.3 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ATG22 PF11700.8 KII84768.1 - 5.3e-150 500.2 9.6 6e-150 500.0 9.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KII84768.1 - 2.2e-07 30.1 57.2 0.00027 20.0 14.3 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily Presenilin PF01080.17 KII84769.1 - 0.096 11.4 0.2 0.075 11.8 0.2 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KII84769.1 - 7 5.8 6.6 7.7 5.6 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 KII84769.1 - 7.4 6.3 13.2 9.7 5.9 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1192 PF06698.11 KII84770.1 - 0.18 11.9 0.4 0.62 10.2 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) 2OG-FeII_Oxy_3 PF13640.6 KII84771.1 - 1.3e-08 35.6 0.0 3.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EPL1 PF10513.9 KII84772.1 - 1.3e-22 80.9 0.6 2.4e-21 76.8 0.0 2.6 2 0 0 2 2 2 1 Enhancer of polycomb-like adh_short_C2 PF13561.6 KII84773.1 - 0.017 14.7 0.0 0.018 14.6 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII84774.1 - 1.5e-33 115.9 0.1 1.8e-33 115.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII84774.1 - 7.9e-29 100.9 0.1 9.9e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII84774.1 - 1.2e-05 25.4 0.1 1.6e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 KR domain HEM4 PF02602.15 KII84774.1 - 0.01 15.2 0.2 0.031 13.6 0.1 1.7 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Xan_ur_permease PF00860.20 KII84775.1 - 2.6e-24 85.7 34.0 8.1e-14 51.1 15.9 2.5 2 2 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 KII84775.1 - 0.00098 19.5 2.6 0.00098 19.5 2.6 2.7 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily FA_hydroxylase PF04116.13 KII84776.1 - 4.5e-24 85.3 19.5 4.5e-24 85.3 19.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DDE_Tnp_4 PF13359.6 KII84777.1 - 1.8e-15 57.0 0.0 2.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KII84777.1 - 0.00066 19.4 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Trp_oprn_chp PF09534.10 KII84779.1 - 1.8 8.3 6.6 11 5.8 1.1 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SNARE_assoc PF09335.11 KII84780.1 - 4.4e-16 59.5 7.4 9e-16 58.4 7.4 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Pkinase_Tyr PF07714.17 KII84781.1 - 3.6e-38 131.3 0.0 6e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII84781.1 - 1.8e-34 119.3 0.0 2.9e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF4238 PF14022.6 KII84781.1 - 3.3e-09 36.7 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.23 KII84781.1 - 4.5e-05 23.5 0.0 9.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KII84781.1 - 0.002 17.4 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Peptidase_S9 PF00326.21 KII84782.1 - 2.9e-38 131.5 0.0 3.9e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KII84782.1 - 9e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KII84782.1 - 1.6e-05 24.3 0.0 0.00039 19.8 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII84782.1 - 0.0019 17.9 0.2 0.2 11.2 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold PD40 PF07676.12 KII84782.1 - 0.0071 16.3 5.5 0.011 15.6 0.3 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KII84782.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KII84782.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein AXE1 PF05448.12 KII84782.1 - 0.22 10.1 0.5 2.4 6.7 0.1 2.4 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Cys_Met_Meta_PP PF01053.20 KII84783.1 - 7.2e-146 485.6 0.0 8.2e-146 485.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KII84783.1 - 1.5e-10 40.9 0.7 3e-10 40.0 0.7 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KII84783.1 - 1.8e-10 40.3 0.6 1.8e-10 40.3 0.6 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KII84783.1 - 1.6e-09 37.4 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KII84783.1 - 0.00024 19.8 0.1 0.00033 19.3 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KII84783.1 - 0.00032 20.1 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KII84783.1 - 0.00049 19.1 0.1 0.00078 18.4 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Asparaginase_C PF17763.1 KII84783.1 - 0.035 14.3 0.2 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain FAD_binding_3 PF01494.19 KII84784.1 - 1.2e-22 80.6 0.0 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KII84784.1 - 0.00012 21.5 0.0 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII84784.1 - 0.00012 21.8 0.1 0.17 11.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII84784.1 - 0.00091 19.4 0.1 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KII84784.1 - 0.01 14.9 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 KII84784.1 - 0.052 12.8 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII84784.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KII84784.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 KII84784.1 - 0.2 10.3 0.0 0.4 9.3 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein LRR_4 PF12799.7 KII84787.1 - 0.83 10.2 4.2 12 6.5 0.3 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) dsrm PF00035.26 KII84788.1 - 0.01 16.5 0.2 2.8 8.7 0.1 3.4 4 0 0 4 4 4 0 Double-stranded RNA binding motif Dicer_dimer PF03368.14 KII84788.1 - 0.3 11.3 5.1 6.9 6.9 0.0 3.7 4 0 0 4 4 4 0 Dicer dimerisation domain DUF908 PF06012.12 KII84788.1 - 5 6.4 5.2 9.2 5.6 5.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PhyH PF05721.13 KII84789.1 - 1.4e-12 48.3 0.1 2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SIR2 PF02146.17 KII84790.1 - 2.8e-32 112.0 0.0 6.2e-31 107.7 0.0 2.5 1 1 0 1 1 1 1 Sir2 family DUF812 PF05667.11 KII84792.1 - 0.013 14.5 9.8 0.018 14.0 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SWI-SNF_Ssr4 PF08549.10 KII84792.1 - 0.049 12.3 2.5 0.078 11.6 2.5 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FapA PF03961.13 KII84792.1 - 0.09 11.4 2.1 0.13 10.9 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Miga PF10265.9 KII84792.1 - 0.14 11.1 1.6 0.19 10.7 1.6 1.2 1 0 0 1 1 1 0 Mitoguardin FlxA PF14282.6 KII84792.1 - 0.21 11.6 2.2 0.32 11.0 0.9 1.9 2 0 0 2 2 2 0 FlxA-like protein HAUS-augmin3 PF14932.6 KII84792.1 - 0.25 10.9 4.4 0.31 10.6 3.3 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 FTA4 PF13093.6 KII84792.1 - 0.27 11.1 7.1 5.2 6.9 7.0 2.2 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Jnk-SapK_ap_N PF09744.9 KII84792.1 - 0.41 10.9 9.3 0.27 11.5 6.5 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DASH_Spc19 PF08287.11 KII84792.1 - 0.43 10.5 10.3 0.93 9.4 10.3 1.6 1 0 0 1 1 1 0 Spc19 DUF4559 PF15112.6 KII84792.1 - 0.58 9.8 3.1 0.98 9.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Exonuc_VII_L PF02601.15 KII84792.1 - 0.62 9.6 3.9 1.1 8.8 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 KII84792.1 - 1.3 7.5 7.1 0.096 11.2 2.3 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4200 PF13863.6 KII84792.1 - 3.4 8.1 9.8 8.8 6.8 9.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-H PF05837.12 KII84792.1 - 6.3 7.3 7.8 16 6.0 7.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PLU-1 PF08429.11 KII84794.1 - 0.00059 19.1 4.1 0.00091 18.5 4.1 1.2 1 0 0 1 1 1 1 PLU-1-like protein ERM PF00769.19 KII84794.1 - 0.003 17.4 10.0 0.0046 16.8 10.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4201 PF13870.6 KII84794.1 - 0.0042 16.8 2.2 0.0042 16.8 2.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Uds1 PF15456.6 KII84794.1 - 0.014 15.6 3.0 0.63 10.2 0.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation DUF4407 PF14362.6 KII84794.1 - 0.03 13.7 2.9 0.049 13.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 KII84794.1 - 0.035 14.3 7.6 0.12 12.6 1.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FmiP_Thoc5 PF09766.9 KII84794.1 - 0.066 12.5 2.9 0.17 11.2 0.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Fez1 PF06818.15 KII84794.1 - 0.083 13.3 6.9 0.15 12.5 6.9 1.4 1 0 0 1 1 1 0 Fez1 APG6_N PF17675.1 KII84794.1 - 0.092 13.3 13.4 0.2 12.2 13.4 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region POX PF07526.11 KII84794.1 - 0.18 12.4 3.8 51 4.4 5.3 2.5 1 1 0 2 2 2 0 Associated with HOX Seryl_tRNA_N PF02403.22 KII84794.1 - 0.53 10.5 11.2 0.43 10.8 4.7 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 KII84794.1 - 0.56 10.5 6.9 8.7 6.7 0.9 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain HALZ PF02183.18 KII84794.1 - 0.6 10.4 5.1 0.28 11.5 0.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper HAUS6_N PF14661.6 KII84794.1 - 0.61 9.6 11.7 0.042 13.4 3.8 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PRKG1_interact PF15898.5 KII84794.1 - 1.2 10.1 13.7 0.6 11.0 7.4 2.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Sec34 PF04136.15 KII84794.1 - 2.1 8.2 4.8 1.5 8.7 0.6 2.2 1 1 1 2 2 2 0 Sec34-like family bZIP_1 PF00170.21 KII84794.1 - 2.4 8.3 9.4 8.4 6.6 0.4 2.9 2 1 1 3 3 3 0 bZIP transcription factor HIP1_clath_bdg PF16515.5 KII84794.1 - 2.9 8.6 9.1 0.78 10.4 2.1 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SKA2 PF16740.5 KII84794.1 - 3.4 7.5 8.4 2.7 7.8 0.2 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 AKNA PF12443.8 KII84794.1 - 3.5 8.3 9.8 2.7 8.7 2.4 3.2 1 1 2 3 3 3 0 AT-hook-containing transcription factor GAS PF13851.6 KII84794.1 - 6.5 6.1 12.7 10 5.4 5.1 2.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KII84794.1 - 8.3 7.1 9.7 9.1 7.0 0.5 3.2 1 1 1 2 2 2 0 Initiation control protein YabA PAP2_3 PF14378.6 KII84796.1 - 2.6e-21 76.2 21.4 2.6e-21 76.2 21.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KII84796.1 - 3.9e-09 36.4 7.8 3.9e-09 36.4 7.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily GPCR_chapero_1 PF11904.8 KII84796.1 - 0.1 12.0 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 GPCR-chaperone Peptidase_M36 PF02128.15 KII84797.1 - 4.9e-161 536.0 2.3 6.5e-161 535.6 2.3 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KII84797.1 - 8.4e-12 44.7 1.4 1.8e-11 43.7 1.4 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KII84797.1 - 0.019 14.8 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_23 PF13489.6 KII84799.1 - 2.4e-07 30.8 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84799.1 - 5.7e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII84799.1 - 0.00061 20.4 0.0 0.0018 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII84799.1 - 0.00099 19.8 0.0 0.0035 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII84799.1 - 0.0049 16.7 0.0 0.073 12.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KII84801.1 - 3.8e-59 200.1 1.8 4.7e-59 199.8 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII84801.1 - 1.2e-42 145.6 3.1 1.6e-42 145.2 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII84801.1 - 3.9e-11 43.2 2.0 7.6e-11 42.2 2.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KII84801.1 - 0.00058 19.4 0.7 0.0025 17.3 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flavodoxin_5 PF12724.7 KII84801.1 - 0.0079 16.4 1.4 2.4 8.4 0.1 2.7 2 2 0 2 2 2 2 Flavodoxin domain Flavodoxin_1 PF00258.25 KII84801.1 - 0.015 15.5 0.1 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin THF_DHG_CYH_C PF02882.19 KII84801.1 - 0.043 13.1 1.4 0.089 12.1 1.2 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TLP1_add_C PF18313.1 KII84801.1 - 0.085 12.8 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain adh_short_C2 PF13561.6 KII84802.1 - 1.8e-52 178.2 4.6 2.1e-50 171.5 4.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII84802.1 - 3.6e-41 140.8 2.4 1.3e-39 135.7 2.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII84802.1 - 4.4e-08 33.3 1.9 1.2e-07 31.9 1.9 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII84802.1 - 0.018 14.4 0.0 0.078 12.3 0.0 1.8 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 KII84802.1 - 0.023 14.6 0.9 0.037 13.9 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 KII84802.1 - 0.15 11.9 7.9 4.2 7.2 0.7 3.0 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein Abhydrolase_3 PF07859.13 KII84803.1 - 7e-11 42.4 0.2 1e-09 38.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII84803.1 - 7.8e-05 21.7 0.7 0.00051 19.1 0.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KII84803.1 - 0.0011 18.3 0.0 0.0036 16.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII84803.1 - 0.0036 17.9 3.2 0.0064 17.1 2.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KII84803.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KII84803.1 - 0.064 12.7 0.0 0.6 9.5 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family RhoGEF PF00621.20 KII84804.1 - 2.5e-05 24.6 0.0 2.6e-05 24.6 0.0 1.0 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.20 KII84805.1 - 3.1e-54 184.2 18.6 3.1e-54 184.2 18.6 1.7 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 KII84805.1 - 1.1e-11 44.4 0.1 2.2e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 KII84805.1 - 4.7e-11 42.6 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MFS_MOT1 PF16983.5 KII84805.1 - 0.01 16.2 3.5 0.01 16.2 3.5 3.7 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily UCR_UQCRX_QCR9 PF05365.12 KII84805.1 - 0.11 12.5 0.1 2.3 8.2 0.0 3.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like NUDIX_2 PF13869.6 KII84807.1 - 1.6e-83 278.9 0.0 1.8e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Abhydrolase_3 PF07859.13 KII84808.1 - 4.7e-10 39.7 0.1 5.1e-09 36.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KII84808.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KII84808.1 - 0.0028 16.6 0.2 0.0046 15.9 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KII84808.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AstA PF04958.12 KII84808.1 - 0.049 12.2 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Abhydrolase_3 PF07859.13 KII84809.1 - 1e-12 48.4 0.2 2.3e-11 44.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII84809.1 - 0.00023 20.2 0.1 0.016 14.1 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 KII84809.1 - 0.00043 19.3 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KII84809.1 - 0.011 15.0 0.1 0.14 11.4 0.1 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII84809.1 - 0.053 13.0 0.0 0.31 10.5 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KII84809.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 KII84810.1 - 4.2e-14 52.9 0.4 1.9e-13 50.8 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII84810.1 - 0.00013 22.6 1.9 0.00018 22.2 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KII84810.1 - 0.00031 19.7 0.5 0.0029 16.6 0.5 2.0 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KII84810.1 - 0.00052 19.0 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KII84810.1 - 0.00055 19.3 0.2 0.0013 18.0 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII84810.1 - 0.0012 18.4 0.0 0.021 14.3 0.0 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Ras PF00071.22 KII84811.1 - 1e-54 184.5 0.0 1.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII84811.1 - 3.8e-33 114.3 0.0 5.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII84811.1 - 1.5e-13 50.6 0.0 2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII84811.1 - 2.1e-06 27.8 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII84811.1 - 3.3e-06 26.6 0.0 4.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII84811.1 - 0.00064 19.3 0.0 0.0016 18.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KII84811.1 - 0.0099 16.3 0.0 0.017 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KII84811.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KII84811.1 - 0.05 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 KII84811.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 KII84811.1 - 0.18 11.0 1.4 6.5 5.8 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KII84811.1 - 0.21 11.5 0.1 0.61 10.0 0.1 1.7 1 1 0 2 2 2 0 RsgA GTPase Methyltransf_9 PF08003.11 KII84812.1 - 0.021 13.7 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Polysacc_lyase PF14099.6 KII84814.1 - 0.00021 21.2 0.5 0.0018 18.2 0.5 2.0 1 1 0 1 1 1 1 Polysaccharide lyase Big_9 PF17963.1 KII84814.1 - 0.04 14.7 2.4 0.61 10.9 0.2 2.6 2 1 0 2 2 2 0 Bacterial Ig domain Hydrophobin PF01185.18 KII84815.1 - 4.8e-16 59.2 10.8 6.3e-16 58.8 10.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin PhoLip_ATPase_N PF16209.5 KII84815.1 - 0.07 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal PMP1_2 PF08114.11 KII84815.1 - 0.15 11.9 2.3 0.41 10.4 2.3 1.8 1 0 0 1 1 1 0 ATPase proteolipid family Pyr_redox_2 PF07992.14 KII84818.1 - 4.7e-14 52.3 0.0 2e-11 43.7 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KII84818.1 - 5.5e-11 41.6 0.0 2.1e-09 36.4 0.0 2.7 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KII84818.1 - 4.2e-09 36.0 0.1 2.9e-05 23.4 0.0 3.4 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KII84818.1 - 2.5e-08 34.1 1.9 4.2e-07 30.1 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII84818.1 - 6.4e-08 32.2 0.4 0.067 12.4 0.0 3.9 3 2 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII84818.1 - 2e-07 31.5 2.2 0.016 15.7 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII84818.1 - 1.3e-06 28.2 7.2 4.5e-06 26.5 1.6 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KII84818.1 - 7.6e-06 25.5 0.2 0.02 14.2 0.0 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KII84818.1 - 1e-05 24.9 5.5 0.0043 16.4 0.4 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KII84818.1 - 1e-05 25.1 4.9 0.00041 19.8 0.4 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII84818.1 - 2.8e-05 24.1 4.3 0.0087 16.1 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.22 KII84818.1 - 0.00018 20.8 6.1 0.022 13.9 1.3 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A Shikimate_DH PF01488.20 KII84818.1 - 0.00025 21.1 0.0 0.41 10.7 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KII84818.1 - 0.00037 19.7 10.0 0.0024 17.0 2.2 2.6 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 KII84818.1 - 0.0036 16.1 6.2 0.11 11.1 2.3 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KII84818.1 - 0.0049 16.1 1.9 0.15 11.3 0.5 2.8 3 0 0 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 KII84818.1 - 0.0081 16.1 1.5 0.0081 16.1 1.5 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KII84818.1 - 0.014 15.9 0.4 0.13 12.7 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KII84818.1 - 0.057 12.8 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KII84818.1 - 0.15 11.7 0.6 0.29 10.7 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KII84818.1 - 0.23 10.7 1.2 2 7.6 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.29 KII84820.1 - 3.3e-06 27.0 0.0 4.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase EOS1 PF12326.8 KII84821.1 - 1.6e-40 138.9 0.0 2.4e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 N-glycosylation protein Diphthamide_syn PF01866.17 KII84822.1 - 1.6e-93 313.5 0.0 2e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein TPR_2 PF07719.17 KII84823.1 - 2.4e-10 39.7 7.1 0.013 15.6 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII84823.1 - 2.8e-09 37.0 7.0 0.00019 22.0 0.0 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII84823.1 - 4.4e-06 26.5 1.7 0.12 12.6 0.3 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII84823.1 - 5.3e-06 26.9 2.0 12 6.5 0.1 5.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII84823.1 - 5.7e-06 25.9 0.1 0.064 13.0 0.0 4.6 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.28 KII84823.1 - 2.2e-05 24.1 0.7 1.7 8.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII84823.1 - 0.00022 21.8 9.3 0.052 14.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII84823.1 - 0.00043 20.5 4.8 12 6.6 0.0 6.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KII84823.1 - 0.0019 17.5 0.9 0.06 12.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KII84823.1 - 0.11 11.8 0.8 11 5.3 0.0 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_9 PF13371.6 KII84823.1 - 0.17 12.0 4.5 44 4.3 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII84823.1 - 0.24 11.7 10.6 3.3 8.1 0.0 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII84823.1 - 1.5 9.6 5.4 47 4.9 0.7 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KII84825.1 - 1.8e-36 121.3 11.2 1.3e-06 28.0 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 KII84825.1 - 2.1e-36 122.3 10.1 2.2e-07 30.4 0.0 10.6 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 KII84825.1 - 3.6e-22 76.7 6.4 6.9e-06 25.9 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII84825.1 - 3.5e-20 70.9 4.2 5.9e-05 23.2 0.0 7.9 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KII84825.1 - 2.3e-19 68.8 10.6 1.4e-08 34.3 0.0 7.5 6 2 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 KII84825.1 - 5.5e-19 68.5 5.0 2.3e-05 24.9 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII84825.1 - 3.1e-17 62.6 12.4 6.7e-06 26.3 0.0 7.5 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KII84825.1 - 3.1e-17 62.8 7.7 8.2e-06 26.2 0.0 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KII84825.1 - 5.3e-16 58.0 11.0 6.4e-07 29.7 0.0 8.3 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KII84825.1 - 8.8e-12 44.2 3.2 0.015 15.3 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KII84825.1 - 7.6e-10 38.8 8.4 0.0036 17.4 0.0 5.8 4 2 3 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KII84825.1 - 7.9e-09 35.6 1.8 0.0017 18.5 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KII84825.1 - 5.1e-07 29.4 0.7 0.0084 15.5 0.5 3.3 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 KII84825.1 - 2.1e-05 24.9 5.0 0.04 14.5 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 KII84825.1 - 0.0047 16.7 11.1 0.29 10.8 0.0 4.7 4 2 1 5 5 5 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 KII84825.1 - 0.0049 15.8 0.0 0.0049 15.8 0.0 2.2 2 1 1 3 3 2 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KII84825.1 - 0.01 15.7 13.4 1.4 8.8 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 KII84825.1 - 0.02 14.1 9.2 0.025 13.8 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KII84825.1 - 0.054 13.0 3.0 2.8 7.5 0.0 4.4 4 0 0 4 4 3 0 SHNi-TPR RPN7 PF10602.9 KII84825.1 - 0.072 12.8 4.6 1.6 8.4 0.0 3.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 DUF3856 PF12968.7 KII84825.1 - 0.094 12.8 1.6 16 5.5 0.0 4.2 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 KII84825.1 - 0.18 11.8 2.0 0.48 10.5 0.0 2.8 3 1 1 4 4 3 0 Protein of unknown function (DUF627) UCR_Fe-S_N PF10399.9 KII84825.1 - 0.92 8.9 3.6 2.3 7.7 3.6 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Piwi PF02171.17 KII84826.1 - 2.1e-60 204.5 0.0 4.6e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KII84826.1 - 3.2e-22 79.6 1.6 8.3e-22 78.3 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KII84826.1 - 2.4e-16 59.1 0.0 5.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KII84826.1 - 2.3e-12 46.9 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KII84826.1 - 4.5e-08 33.3 0.0 1.5e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KII84826.1 - 0.00012 22.3 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Zip PF02535.22 KII84827.1 - 3.9e-57 194.0 1.7 1.8e-35 122.7 2.4 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter APA3_viroporin PF11289.8 KII84827.1 - 0.19 11.3 0.5 0.38 10.3 0.5 1.4 1 0 0 1 1 1 0 Coronavirus accessory protein 3a Fungal_trans PF04082.18 KII84828.1 - 6.7e-21 74.5 0.9 9.9e-21 73.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84828.1 - 2.5e-07 30.7 6.7 4.4e-07 29.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NopRA1 PF16201.5 KII84828.1 - 0.0027 17.3 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Aminotran_1_2 PF00155.21 KII84829.1 - 2.6e-14 53.2 0.0 1.4e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II HpcH_HpaI PF03328.14 KII84830.1 - 1.5e-43 148.5 0.1 2e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family COesterase PF00135.28 KII84831.1 - 5.5e-68 230.1 0.0 6.8e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII84831.1 - 0.0014 18.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII84831.1 - 0.036 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family HNH_2 PF13391.6 KII84833.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF4332 PF14229.6 KII84834.1 - 0.21 11.8 0.7 0.37 11.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HNH_2 PF13391.6 KII84835.1 - 0.022 14.9 0.1 0.065 13.4 0.1 1.8 1 0 0 1 1 1 0 HNH endonuclease HNH_2 PF13391.6 KII84836.1 - 0.031 14.4 0.2 0.27 11.4 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease DUF4817 PF16087.5 KII84836.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) MFS_1 PF07690.16 KII84837.1 - 2.8e-26 92.3 32.6 3.7e-26 91.9 32.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 KII84838.1 - 6.7e-38 130.9 0.6 1.4e-37 129.8 0.6 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KII84838.1 - 9e-15 55.1 7.7 4.5e-13 49.5 1.8 2.2 1 1 1 2 2 2 2 Amidohydrolase family Peptidase_M48_N PF16491.5 KII84839.1 - 3.1e-59 199.9 3.1 3.1e-59 199.9 3.1 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KII84839.1 - 3.5e-36 124.8 0.0 6.8e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KII84839.1 - 0.022 14.0 0.2 0.035 13.3 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 KII84839.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 SprT-like family MgtE PF01769.16 KII84839.1 - 4.1 7.8 12.4 0.33 11.3 0.5 2.8 2 1 0 2 2 2 0 Divalent cation transporter EthD PF07110.11 KII84840.1 - 3.1e-10 41.0 0.0 4.2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KII84840.1 - 1.9e-05 25.1 0.0 2.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase SHOCT PF09851.9 KII84840.1 - 0.19 11.5 1.8 7.2 6.5 0.6 2.3 2 0 0 2 2 2 0 Short C-terminal domain EthD PF07110.11 KII84841.1 - 2e-11 44.9 0.0 2.4e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KII84841.1 - 0.00065 20.1 0.0 0.0011 19.4 0.0 1.4 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase WD40 PF00400.32 KII84842.1 - 4.4e-41 138.1 18.3 3.1e-07 31.0 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII84842.1 - 0.00073 19.8 0.5 1.2 9.4 0.1 4.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII84842.1 - 0.003 16.3 0.7 5.7 5.5 0.0 4.0 1 1 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KII84842.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 WD40-like domain TFIIS_M PF07500.14 KII84843.1 - 4.4e-33 114.1 0.3 4.4e-33 114.1 0.3 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KII84843.1 - 2.9e-15 55.8 11.2 5e-15 55.1 11.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KII84843.1 - 5.6e-10 39.1 1.0 5.6e-10 39.1 1.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF4592 PF15262.6 KII84844.1 - 2.9 8.6 8.6 2.2 9.0 0.0 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4592) Mito_carr PF00153.27 KII84846.1 - 2.8e-19 68.8 4.1 6.2e-08 32.4 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad60-SLD PF11976.8 KII84847.1 - 8e-13 48.0 0.0 9.6e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KII84847.1 - 1.5e-06 27.8 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 KII84847.1 - 0.00027 21.1 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 TUG ubiquitin-like domain Cobl PF09469.10 KII84847.1 - 0.054 13.7 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain zf-CSL PF05207.13 KII84848.1 - 1.3e-21 76.1 0.5 1.5e-21 75.8 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger Shisa PF13908.6 KII84849.1 - 0.49 10.6 2.9 0.52 10.5 2.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator GFO_IDH_MocA PF01408.22 KII84850.1 - 2.9e-16 60.4 0.0 5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GIDA PF01134.22 KII84851.1 - 5.3e-136 453.8 0.0 2.2e-134 448.5 0.0 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KII84851.1 - 6.4e-58 196.4 0.0 8.5e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 KII84851.1 - 0.00037 19.7 2.0 0.56 9.2 0.7 2.7 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KII84851.1 - 0.00065 19.0 1.5 0.017 14.3 1.5 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII84851.1 - 0.025 14.5 1.0 0.07 13.1 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KII84851.1 - 0.043 12.5 1.3 4.4 5.9 0.2 3.1 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.25 KII84852.1 - 2.2e-23 82.7 0.0 3.2e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII84852.1 - 7.3e-21 74.8 0.0 9.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KII84852.1 - 0.039 13.8 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBDS PF01172.18 KII84852.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein KCH PF16944.5 KII84855.1 - 0.00073 19.4 1.9 0.001 18.9 1.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel Pro_isomerase PF00160.21 KII84856.1 - 1e-48 165.6 0.1 1.1e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PIP5K PF01504.18 KII84857.1 - 1.9e-48 165.1 0.0 2.8e-38 131.7 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cys_rich_KTR PF14205.6 KII84857.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich KTR GMC_oxred_N PF00732.19 KII84858.1 - 5.3e-64 216.4 0.0 7.5e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII84858.1 - 1.1e-34 120.1 0.0 1.9e-34 119.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII84858.1 - 4.1e-06 26.1 0.1 6.1e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KII84858.1 - 0.00017 20.8 0.3 0.0026 16.9 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KII84858.1 - 0.0016 17.7 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KII84858.1 - 0.041 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII84858.1 - 0.19 10.4 0.6 0.28 9.9 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein DIM1 PF02966.16 KII84859.1 - 6.2e-68 226.7 0.0 7e-68 226.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KII84859.1 - 0.0002 21.3 0.1 0.00028 20.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KII84859.1 - 0.039 14.3 0.3 0.055 13.8 0.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.7 KII84860.1 - 8.2e-07 28.8 2.1 2.2e-06 27.5 2.1 1.8 1 0 0 1 1 1 1 F-box-like DUF2773 PF10971.8 KII84860.1 - 0.12 12.5 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) DUF2470 PF10615.9 KII84861.1 - 9.7e-19 67.8 0.0 2.3e-18 66.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KII84861.1 - 5e-10 39.6 4.7 8.8e-10 38.8 4.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) DUF2470 PF10615.9 KII84863.1 - 1.1e-17 64.4 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KII84863.1 - 4.2e-07 30.2 2.3 8.2e-07 29.3 2.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) Rad60-SLD PF11976.8 KII84867.1 - 2.1e-21 75.5 0.1 2.9e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KII84867.1 - 4.3e-12 45.6 0.0 5.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 KII84869.1 - 6.7e-09 35.5 0.0 2.5e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 KII84869.1 - 6.5e-06 25.7 0.0 1.5e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KII84869.1 - 7.6e-05 22.1 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KII84869.1 - 0.0011 19.0 0.0 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII84869.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KII84870.1 - 1.6e-07 31.0 0.0 1.2e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KII84870.1 - 6.9e-05 22.3 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII84870.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII84870.1 - 0.021 14.1 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Choline_kinase PF01633.20 KII84870.1 - 0.21 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KII84873.1 - 1.3e-09 37.8 0.0 2.4e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KII84873.1 - 8.9e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KII84873.1 - 0.0058 16.0 0.0 0.091 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KII84873.1 - 0.0059 16.6 0.2 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII84873.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase F-box-like PF12937.7 KII84874.1 - 7.3e-06 25.8 0.8 6.5e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII84874.1 - 0.0012 18.7 2.1 0.0041 17.0 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 KII84874.1 - 0.0073 16.7 2.4 12 6.5 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII84874.1 - 0.0095 15.7 0.1 0.56 10.0 0.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat 2OG-FeII_Oxy_2 PF13532.6 KII84875.1 - 8.8e-22 78.3 0.1 1.1e-21 77.9 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltrans PF00432.21 KII84876.1 - 5e-51 170.1 4.0 5.8e-10 38.7 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KII84876.1 - 0.0017 17.5 0.0 0.0053 15.9 0.0 1.7 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain F-box-like PF12937.7 KII84878.1 - 2.1e-06 27.5 0.4 1.9e-05 24.5 0.4 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII84878.1 - 0.04 13.8 0.1 6.8 6.7 0.1 2.6 2 0 0 2 2 2 0 F-box domain Rhodanese PF00581.20 KII84879.1 - 8.7e-08 32.6 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 KII84880.1 - 8.5e-62 208.9 0.0 1.9e-61 207.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84880.1 - 1.2e-35 123.0 0.0 3.7e-35 121.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII84880.1 - 7.1e-06 26.1 0.1 2.6e-05 24.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII84880.1 - 2.7e-05 23.6 0.0 6.2e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KII84880.1 - 4.6e-05 22.9 0.8 7.5e-05 22.2 0.8 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KII84880.1 - 0.00036 19.6 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KII84880.1 - 0.011 15.3 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KII84880.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KII84880.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KII84880.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family KAAG1 PF15354.6 KII84880.1 - 0.16 12.5 1.9 12 6.5 0.2 2.9 2 0 0 2 2 2 0 Kidney-associated antigen 1 AA_permease_2 PF13520.6 KII84881.1 - 1.3e-75 254.9 52.3 1.5e-75 254.7 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII84881.1 - 1.6e-17 63.2 43.7 2.2e-17 62.8 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease SNF2_N PF00176.23 KII84885.1 - 1.2e-56 192.0 1.0 1.7e-55 188.2 0.0 3.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII84885.1 - 3.6e-18 65.9 0.0 2.6e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII84885.1 - 5.5e-10 39.5 0.0 7.7e-07 29.3 0.0 3.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dicty_REP PF05086.12 KII84885.1 - 0.039 12.0 0.2 0.062 11.3 0.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HDA2-3 PF11496.8 KII84885.1 - 0.075 12.2 0.0 0.55 9.3 0.0 2.4 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Presenilin PF01080.17 KII84885.1 - 0.16 10.7 6.2 0.27 10.0 6.2 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KII84885.1 - 0.34 9.7 4.9 0.55 9.0 4.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SWIRM-assoc_2 PF16496.5 KII84885.1 - 4.2 6.1 16.7 9.9 4.9 16.7 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF3433 PF11915.8 KII84886.1 - 1.1e-16 61.0 5.4 1.1e-16 61.0 5.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF3821 PF12863.7 KII84886.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) DUF3433 PF11915.8 KII84887.1 - 2.7e-10 40.5 1.7 2.7e-10 40.5 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) CysG_dimeriser PF10414.9 KII84887.1 - 0.16 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region DUF455 PF04305.14 KII84888.1 - 4.6e-91 304.8 0.0 5.9e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KII84888.1 - 6.6e-07 29.2 0.2 1.4e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KII84888.1 - 0.00021 21.2 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain TauD PF02668.16 KII84889.1 - 4.7e-51 174.1 0.5 5.9e-51 173.8 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4527 PF15030.6 KII84889.1 - 0.044 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Birna_RdRp PF04197.12 KII84889.1 - 0.18 10.1 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Aa_trans PF01490.18 KII84890.1 - 3.2e-32 111.7 35.1 3.7e-32 111.5 35.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM70 PF06979.12 KII84890.1 - 8.5 6.8 7.4 0.6 10.5 0.2 2.8 3 0 0 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex SPC12 PF06645.13 KII84893.1 - 2.4e-23 82.0 0.6 2.8e-23 81.8 0.6 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) TMEM252 PF15664.5 KII84893.1 - 0.16 11.7 0.2 0.22 11.2 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 252 family Pkinase PF00069.25 KII84894.1 - 2.1e-65 220.7 0.1 2.2e-64 217.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84894.1 - 4.1e-37 127.9 0.1 1.5e-36 126.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KII84894.1 - 8.9e-18 63.8 0.1 1.5e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KII84894.1 - 3.8e-06 26.4 0.2 6.2e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII84894.1 - 7.5e-05 22.2 0.0 0.00017 21.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KII84894.1 - 9e-05 22.5 0.1 0.0036 17.3 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII84894.1 - 0.00022 20.3 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain WaaY PF06176.11 KII84894.1 - 0.0022 17.7 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KII84894.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.18 KII84896.1 - 2.6e-20 72.6 0.0 4.6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII84896.1 - 8.1e-08 32.3 10.0 1.5e-07 31.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KII84899.1 - 1.4e-05 25.1 13.1 2.3e-05 24.4 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII84900.1 - 2.8e-12 46.2 0.6 8.7e-12 44.6 0.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain E3_UbLigase_R4 PF13764.6 KII84900.1 - 0.18 9.9 0.1 0.25 9.4 0.1 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Fe_dep_repress PF01325.19 KII84900.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain ARS2 PF04959.13 KII84900.1 - 0.52 10.7 1.7 0.7 10.2 0.5 1.8 2 0 0 2 2 2 0 Arsenite-resistance protein 2 CBFD_NFYB_HMF PF00808.23 KII84901.1 - 9e-10 38.7 0.3 1.8e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KII84901.1 - 0.0035 17.4 0.2 0.0061 16.7 0.2 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Phosphodiest PF01663.22 KII84903.1 - 2.3e-12 47.2 0.3 2.3e-12 47.2 0.3 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KII84903.1 - 0.0038 16.7 0.0 0.022 14.1 0.0 1.9 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KII84903.1 - 0.0081 15.6 0.4 0.018 14.4 0.4 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily RicinB_lectin_2 PF14200.6 KII84904.1 - 3.5e-11 43.7 0.0 4.9e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KII84904.1 - 0.0086 16.3 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KII84906.1 - 1.4e-21 77.0 8.5 2.2e-11 44.3 0.9 2.8 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KII84906.1 - 0.00013 22.2 1.1 0.016 15.5 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_15 PF01793.16 KII84909.1 - 1e-123 412.7 9.6 1.2e-123 412.5 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.7 KII84909.1 - 0.53 10.5 2.1 0.98 9.7 2.1 1.5 1 0 0 1 1 1 0 EGF domain Acid_PPase PF12689.7 KII84910.1 - 4.1e-62 209.0 0.0 4.6e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hva1_TUDOR PF11160.8 KII84912.1 - 2.1e-13 50.2 1.5 2.6e-13 49.9 1.5 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain ProQ_C PF17516.2 KII84912.1 - 0.038 13.4 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 ProQ C-terminal domain IstB_IS21_ATP PF08483.11 KII84913.1 - 0.44 10.5 2.6 1.3 8.9 2.6 1.9 1 0 0 1 1 1 0 IstB-like ATP binding N-terminal DCB PF16213.5 KII84914.1 - 1.1e-52 178.3 1.6 3.6e-52 176.6 1.2 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KII84914.1 - 4.9e-43 146.8 2.3 9.6e-42 142.6 2.8 2.9 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KII84914.1 - 1.1e-42 146.2 2.1 1.7e-25 89.3 0.4 3.7 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KII84914.1 - 3.9e-06 26.6 0.0 0.0006 19.6 0.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Bromodomain PF00439.25 KII84915.1 - 3.7e-21 75.0 0.0 9e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Fe_bilin_red PF05996.12 KII84915.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Homeodomain PF00046.29 KII84916.1 - 8.3e-15 54.4 1.0 1.7e-14 53.4 1.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII84916.1 - 0.025 14.5 0.1 0.025 14.5 0.1 2.2 3 0 0 3 3 3 0 Homeobox KN domain zf-RING_2 PF13639.6 KII84918.1 - 3.7e-10 40.0 11.1 5.7e-10 39.4 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII84918.1 - 9.7e-09 35.0 9.2 1.5e-08 34.4 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII84918.1 - 1.2e-08 34.7 11.0 1.7e-08 34.1 11.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII84918.1 - 2.3e-07 30.6 6.1 3.2e-07 30.1 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KII84918.1 - 4.8e-07 30.0 7.2 8.6e-07 29.2 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KII84918.1 - 3.5e-06 26.9 8.6 5.1e-06 26.3 8.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII84918.1 - 3.8e-06 26.8 7.5 7.4e-06 25.9 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KII84918.1 - 0.00082 19.2 6.9 0.0014 18.5 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KII84918.1 - 0.016 14.9 7.8 0.031 14.0 7.8 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KII84918.1 - 0.022 14.9 10.1 0.038 14.1 10.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KII84918.1 - 0.038 14.0 4.8 0.089 12.8 4.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Siva PF05458.12 KII84918.1 - 0.052 13.2 1.4 0.082 12.6 1.4 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-P11 PF03854.14 KII84918.1 - 0.071 12.8 7.6 2.1 8.1 7.7 2.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KII84918.1 - 0.35 10.7 6.6 0.61 9.9 6.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KII84918.1 - 1.6 8.8 5.4 3 7.9 5.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KII84918.1 - 3.7 7.9 9.5 7.3 6.9 7.9 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain GETHR PF05671.11 KII84919.1 - 0.009 15.4 6.4 3.8 7.0 3.5 4.7 2 2 0 2 2 2 2 GETHR pentapeptide repeat (5 copies) Ank_5 PF13857.6 KII84920.1 - 1.4e-08 34.8 0.4 3.8e-08 33.4 0.5 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII84920.1 - 7.4e-08 32.9 0.0 0.00028 21.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII84920.1 - 1.7e-07 31.7 0.0 0.00054 20.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KII84920.1 - 2.3e-06 27.8 0.2 1.9e-05 24.9 0.2 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 KII84920.1 - 1.5e-05 25.0 0.0 0.0047 17.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Pyr_redox_2 PF07992.14 KII84921.1 - 3.1e-25 89.0 0.0 1.6e-23 83.4 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII84921.1 - 7.3e-12 45.7 0.5 3.6e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 KII84921.1 - 0.0026 17.5 0.3 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase K_oxygenase PF13434.6 KII84921.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KII84921.1 - 0.041 13.5 3.9 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KII84921.1 - 0.043 12.7 0.8 12 4.6 0.1 3.1 4 0 0 4 4 4 0 Tryptophan halogenase Thi4 PF01946.17 KII84921.1 - 0.068 12.4 0.1 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family DUF5541 PF17695.1 KII84921.1 - 0.09 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5541) NAD_binding_8 PF13450.6 KII84921.1 - 0.13 12.5 0.4 17 5.7 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MscS_porin PF12795.7 KII84923.1 - 6.4e-06 25.9 1.6 7.1e-06 25.7 1.6 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain T3SS_needle_E PF08988.10 KII84923.1 - 0.0065 16.6 3.1 0.47 10.6 0.4 2.2 1 1 1 2 2 2 2 Type III secretion system, cytoplasmic E component of needle Alanine_zipper PF11839.8 KII84923.1 - 0.007 16.7 1.6 0.01 16.2 1.6 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein OEP PF02321.18 KII84923.1 - 0.013 15.4 1.6 0.028 14.2 1.6 1.5 1 1 0 1 1 1 0 Outer membrane efflux protein KELK PF15796.5 KII84923.1 - 0.014 15.9 0.3 0.02 15.3 0.3 1.2 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase TolA_bind_tri PF16331.5 KII84923.1 - 0.016 15.3 3.2 0.02 15.0 3.2 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation BLOC1S3 PF15753.5 KII84923.1 - 0.018 15.2 1.7 0.023 14.8 1.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF2524 PF10732.9 KII84923.1 - 0.029 14.7 4.3 0.063 13.6 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DPM3 PF08285.11 KII84923.1 - 0.029 14.6 1.0 0.28 11.4 0.1 2.1 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) KxDL PF10241.9 KII84923.1 - 0.029 14.6 1.2 0.07 13.4 1.2 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein Spc7 PF08317.11 KII84923.1 - 0.029 13.2 0.3 0.031 13.2 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 KII84923.1 - 0.033 14.2 0.8 0.042 13.9 0.8 1.1 1 0 0 1 1 1 0 Laminin Domain II SKA2 PF16740.5 KII84923.1 - 0.036 13.8 6.0 1.2 9.0 0.6 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3584 PF12128.8 KII84923.1 - 0.044 11.3 5.3 0.046 11.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 KII84923.1 - 0.05 13.3 0.2 0.063 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 KII84923.1 - 0.069 13.2 2.0 0.082 13.0 2.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4715 PF15835.5 KII84923.1 - 0.081 13.0 0.5 0.099 12.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DUF948 PF06103.11 KII84923.1 - 0.096 13.0 0.8 0.13 12.6 0.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DHR10 PF18595.1 KII84923.1 - 0.1 12.6 2.1 0.3 11.2 2.2 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1640 PF07798.11 KII84923.1 - 0.12 12.4 0.5 0.12 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Syntaxin_2 PF14523.6 KII84923.1 - 0.15 12.5 1.3 0.18 12.2 1.3 1.2 1 0 0 1 1 1 0 Syntaxin-like protein TMP_2 PF06791.13 KII84923.1 - 0.24 11.0 0.3 0.31 10.7 0.3 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein XhlA PF10779.9 KII84923.1 - 1 9.6 3.9 1.4 9.1 3.4 1.6 1 1 1 2 2 2 0 Haemolysin XhlA DUF2564 PF10819.8 KII84923.1 - 1.1 9.7 8.1 2.1 8.8 8.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) T3SS_needle_F PF09392.10 KII84923.1 - 2.8 8.2 7.6 53 4.1 7.6 2.1 1 1 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DASH_Dam1 PF08653.10 KII84923.1 - 8.6 6.3 8.1 39 4.1 7.4 2.0 1 1 0 1 1 1 0 DASH complex subunit Dam1 TMEM169 PF15052.6 KII84926.1 - 7.1 6.8 13.5 2.6 8.2 0.1 3.1 1 1 2 3 3 3 0 TMEM169 protein family DUF4448 PF14610.6 KII84928.1 - 3.2e-05 23.8 0.1 5.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KII84928.1 - 7.2e-05 23.5 3.3 7.5e-05 23.4 1.2 2.0 1 1 1 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PARP PF00644.20 KII84929.1 - 1.9e-08 34.2 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KII84929.1 - 2.3e-06 27.3 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2 PF00096.26 KII84930.1 - 5.1e-08 32.9 8.0 1.9e-05 24.8 2.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII84930.1 - 1e-05 25.7 9.7 0.00016 21.9 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KII84930.1 - 2.3e-05 24.6 2.0 0.0025 18.2 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII84930.1 - 0.00038 21.1 4.9 0.034 15.0 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KII84930.1 - 0.0028 17.7 1.0 1.9 8.7 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain GAGA PF09237.11 KII84930.1 - 0.037 13.8 0.2 0.093 12.6 0.2 1.6 1 0 0 1 1 1 0 GAGA factor Zn_ribbon_SprT PF17283.2 KII84930.1 - 2.4 8.1 7.4 4.1 7.4 6.7 1.7 1 1 0 1 1 1 0 SprT-like zinc ribbon domain GFA PF04828.14 KII84934.1 - 1.1e-22 80.2 0.8 1.5e-22 79.7 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 KII84934.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.11 KII84934.1 - 0.79 9.4 0.1 0.79 9.4 0.1 2.7 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1726 PF08351.11 KII84935.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DNA_mis_repair PF01119.19 KII84936.1 - 5.1e-19 68.1 0.0 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KII84936.1 - 5.7e-14 52.1 0.1 1e-13 51.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KII84936.1 - 6.6e-09 36.3 0.3 2.4e-08 34.5 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KII84937.1 - 4.8e-22 78.3 0.1 1.4e-21 76.8 0.1 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain FmdA_AmdA PF03069.15 KII84938.1 - 4.2e-54 183.8 0.0 2.5e-28 99.0 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family LEA_2 PF03168.13 KII84938.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein G-alpha PF00503.20 KII84939.1 - 3e-103 345.7 0.0 3.5e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII84939.1 - 1.1e-12 47.8 0.1 4.4e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KII84939.1 - 0.0099 16.1 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KII84939.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KII84939.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 KII84939.1 - 0.026 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KII84939.1 - 0.034 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KII84939.1 - 0.062 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KII84939.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KII84939.1 - 0.18 12.1 0.0 0.72 10.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain SNARE_assoc PF09335.11 KII84940.1 - 3.9e-17 62.9 5.7 1e-16 61.5 5.7 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein DNA_binding_1 PF01035.20 KII84941.1 - 4.8e-27 93.9 0.1 5.7e-27 93.7 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Nup84_Nup100 PF04121.13 KII84942.1 - 3.2e-170 567.8 0.0 3.9e-170 567.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 EF-hand_5 PF13202.6 KII84942.1 - 0.15 11.6 0.1 0.4 10.3 0.1 1.7 1 0 0 1 1 1 0 EF hand DnaG_DnaB_bind PF08278.11 KII84942.1 - 0.42 11.2 4.3 15 6.2 0.1 3.6 4 0 0 4 4 4 0 DNA primase DnaG DnaB-binding Solute_trans_a PF03619.16 KII84943.1 - 6.5e-83 278.3 18.4 7.7e-83 278.1 18.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2101 PF09874.9 KII84943.1 - 0.33 10.6 11.6 0.069 12.8 0.8 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) SNARE_assoc PF09335.11 KII84944.1 - 8.8e-17 61.7 5.7 8.8e-17 61.7 5.7 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4153 PF13687.6 KII84944.1 - 0.037 13.7 4.7 0.63 9.6 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4153) DUF3671 PF12420.8 KII84944.1 - 0.071 13.2 6.9 0.72 9.9 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function SfLAP PF11139.8 KII84944.1 - 0.11 11.9 2.1 4 6.8 0.3 2.3 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein EI24 PF07264.11 KII84944.1 - 5.9 7.1 9.8 13 6.0 9.7 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SNARE_assoc PF09335.11 KII84945.1 - 2.1e-16 60.5 6.9 5.1e-16 59.2 6.9 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF3671 PF12420.8 KII84945.1 - 0.31 11.1 4.0 0.27 11.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function PLDc PF00614.22 KII84949.1 - 6.3e-17 61.0 2.6 3.2e-09 36.6 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KII84949.1 - 1.3e-14 54.2 0.5 3.5e-07 30.2 0.1 3.4 3 0 0 3 3 3 3 PLD-like domain Abhydrolase_6 PF12697.7 KII84950.1 - 2.2e-16 61.2 0.9 2.7e-16 60.9 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Plavaka PF18759.1 KII84952.1 - 8.2e-29 100.9 0.1 1.4e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KII84952.1 - 0.0042 17.5 0.4 0.019 15.4 0.4 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type Rhabdo_M1 PF03342.13 KII84952.1 - 0.11 11.8 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Ten1 PF12658.7 KII84952.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Telomere capping, CST complex subunit CMAS PF02353.20 KII84953.1 - 3.5e-64 216.7 0.0 8.3e-64 215.5 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII84953.1 - 3.3e-12 46.9 0.0 6.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII84953.1 - 4.6e-10 40.0 0.0 9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII84953.1 - 3.2e-09 36.8 0.0 5.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII84953.1 - 8.9e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII84953.1 - 6.6e-06 26.8 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KII84953.1 - 4e-05 23.4 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KII84953.1 - 0.00042 19.9 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KII84953.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KII84953.1 - 0.0032 17.2 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KII84953.1 - 0.004 17.1 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KII84953.1 - 0.026 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CHDNT PF08073.12 KII84953.1 - 0.031 14.2 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 CHDNT (NUC034) domain MetW PF07021.12 KII84953.1 - 0.033 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KII84953.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 KII84953.1 - 0.18 11.5 0.0 5.1 6.7 0.0 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Oxidored_q3 PF00499.20 KII84954.1 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PIG-Y PF15159.6 KII84954.1 - 0.056 14.4 0.1 0.12 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y EI24 PF07264.11 KII84954.1 - 0.063 13.5 0.5 0.089 13.0 0.5 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) HAMP PF00672.25 KII84955.1 - 7.7e-43 144.7 18.4 4.1e-08 33.5 0.1 8.8 7 1 0 7 7 7 7 HAMP domain HATPase_c PF02518.26 KII84955.1 - 2e-29 102.4 0.1 1.2e-28 99.8 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KII84955.1 - 3.3e-23 82.0 0.4 1.5e-22 79.9 0.4 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KII84955.1 - 4.6e-17 61.8 1.2 2.4e-16 59.5 1.2 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 KII84955.1 - 0.00015 21.4 1.0 0.06 12.9 0.0 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF4795) APG17 PF04108.12 KII84955.1 - 0.00092 18.4 0.2 0.0039 16.4 0.0 2.2 2 1 0 2 2 2 1 Autophagy protein Apg17 PA-IL PF07828.12 KII84955.1 - 0.3 11.1 4.1 2.4 8.2 0.0 3.7 3 1 1 4 4 4 0 PA-IL-like protein WXG100 PF06013.12 KII84955.1 - 0.45 10.8 13.3 0.26 11.6 0.2 6.0 8 1 1 9 9 9 0 Proteins of 100 residues with WXG T4SS PF07996.11 KII84955.1 - 1.6 9.1 10.0 4.5 7.6 0.6 3.4 2 1 0 3 3 3 0 Type IV secretion system proteins ParE_toxin PF05016.15 KII84956.1 - 0.16 12.6 0.0 0.24 12.0 0.0 1.3 1 1 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE ThrE PF06738.12 KII84961.1 - 5e-53 180.0 20.6 1.3e-52 178.6 6.1 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KII84961.1 - 7.6e-08 32.6 5.8 7.6e-08 32.6 5.8 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Hepatitis_core PF00906.20 KII84962.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Hepatitis_core PF00906.20 KII84963.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen EF-hand_6 PF13405.6 KII84964.1 - 0.0012 18.6 0.0 0.026 14.4 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 KII84964.1 - 0.0068 15.9 0.0 0.11 12.1 0.0 3.0 4 0 0 4 4 4 1 EF hand Prominin PF05478.11 KII84964.1 - 0.0087 14.1 2.0 0.016 13.2 2.0 1.3 1 0 0 1 1 1 1 Prominin EF-hand_5 PF13202.6 KII84964.1 - 0.021 14.3 0.0 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF550 PF04447.12 KII84964.1 - 0.032 14.3 0.2 0.089 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF550) DUF1902 PF08972.11 KII84964.1 - 0.044 13.8 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) EF-hand_7 PF13499.6 KII84964.1 - 0.062 13.7 0.4 0.46 11.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair DUF948 PF06103.11 KII84964.1 - 0.14 12.5 0.8 12 6.3 0.0 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) HeLo PF14479.6 KII84964.1 - 0.19 11.6 4.1 1.5 8.7 0.0 3.4 3 1 1 4 4 4 0 Prion-inhibition and propagation TFIIB PF00382.19 KII84965.1 - 1.4e-35 121.1 0.9 3.5e-18 65.4 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KII84965.1 - 3.6e-29 101.1 9.2 1.9e-27 95.6 1.1 2.4 2 0 0 2 2 2 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KII84965.1 - 3.6e-08 32.8 3.0 8e-08 31.7 3.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KII84965.1 - 0.00018 21.3 1.0 0.31 10.8 0.4 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 KII84965.1 - 0.012 15.6 0.3 0.023 14.7 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon AP3D1 PF06375.11 KII84965.1 - 0.016 15.4 0.4 0.016 15.4 0.4 2.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 zf-RRN7 PF11781.8 KII84965.1 - 0.59 9.9 3.2 1 9.1 3.2 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Rib_recp_KP_reg PF05104.12 KII84965.1 - 2.5 9.1 17.5 0.24 12.4 11.2 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region F-box-like PF12937.7 KII84966.1 - 0.00042 20.2 0.5 0.0011 18.9 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII84967.1 - 1.6e-08 34.3 1.8 3.6e-07 30.0 0.3 2.8 2 0 0 2 2 2 2 F-box-like Transp_cyt_pur PF02133.15 KII84969.1 - 3.8e-89 299.5 37.4 4.4e-89 299.3 37.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2970 PF11174.8 KII84969.1 - 1.1 9.2 6.1 0.21 11.5 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) zf-MYND PF01753.18 KII84970.1 - 1.3e-08 34.8 7.6 3.1e-08 33.6 7.6 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII84970.1 - 3.5 8.0 10.0 9.7 6.6 10.0 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII84971.1 - 6.1e-07 29.4 5.6 6.1e-07 29.4 5.6 2.3 3 0 0 3 3 3 1 MYND finger Prenyltrans PF00432.21 KII84972.1 - 3.8e-35 119.3 8.4 2.1e-06 27.3 0.0 6.2 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KII84972.1 - 0.013 14.6 0.0 3.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain F-box-like PF12937.7 KII84973.1 - 0.00023 21.0 0.1 0.00053 19.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like Pkinase_fungal PF17667.1 KII84976.1 - 3.7e-54 184.1 0.0 1.1e-31 110.0 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KII84976.1 - 0.0085 15.5 0.0 0.048 13.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII84976.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UAA PF08449.11 KII84977.1 - 1.4e-40 139.4 5.6 2.4e-40 138.6 5.6 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KII84977.1 - 6.8e-11 42.5 20.5 2.1e-08 34.4 4.2 4.1 3 1 1 4 4 4 3 EamA-like transporter family CRT-like PF08627.10 KII84977.1 - 0.00032 19.7 1.8 0.068 12.1 0.4 2.3 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KII84977.1 - 0.0046 16.2 1.3 0.27 10.4 0.3 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KII84977.1 - 0.025 13.9 1.9 3.2 7.0 0.4 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Sugar_tr PF00083.24 KII84980.1 - 7.7e-115 384.3 23.5 8.9e-115 384.1 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII84980.1 - 1e-20 74.0 34.3 1e-20 74.0 34.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DEAD PF00270.29 KII84981.1 - 2.3e-07 30.8 0.0 2.7e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII84981.1 - 0.041 13.9 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit BTB PF00651.31 KII84982.1 - 0.00021 21.5 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Copper-bind PF00127.20 KII84983.1 - 0.0017 18.7 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF4655 PF15548.6 KII84983.1 - 9.7 5.0 9.5 16 4.3 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) HMG_box PF00505.19 KII84985.1 - 5e-10 39.6 0.2 5.7e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII84985.1 - 0.0069 17.0 0.1 0.0075 16.8 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain Sacchrp_dh_C PF16653.5 KII84986.1 - 4.1e-86 289.4 0.0 8.1e-86 288.4 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KII84986.1 - 1.1e-67 227.1 0.0 2.6e-67 225.9 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 KII84986.1 - 2.8e-24 85.8 1.5 2e-23 83.1 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 KII84986.1 - 2.3e-23 81.8 0.7 5.3e-23 80.7 0.1 2.0 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 KII84986.1 - 2.8e-07 30.7 0.6 5.2e-06 26.6 0.2 2.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KII84986.1 - 4.3e-07 30.5 0.0 0.00017 22.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII84986.1 - 3.9e-05 24.3 0.1 0.021 15.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 KII84986.1 - 9.4e-05 22.4 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KII84986.1 - 0.03 15.2 0.2 0.1 13.4 0.1 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_18 PF12847.7 KII84986.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 KII84986.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase KR PF08659.10 KII84986.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KII84986.1 - 0.14 12.6 0.1 0.57 10.6 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Spermine_synth PF01564.17 KII84993.1 - 4.2e-66 222.0 0.0 1e-65 220.7 0.0 1.7 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_C PF16653.5 KII84993.1 - 6.5e-51 174.0 0.0 9.8e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KII84993.1 - 1.2e-24 87.0 1.3 1.6e-23 83.3 0.2 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 KII84993.1 - 2.3e-23 81.8 0.1 4.6e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 KII84993.1 - 2.9e-08 33.9 0.2 4.5e-06 26.8 0.2 2.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 KII84993.1 - 4.1e-06 27.4 0.0 0.00069 20.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 KII84993.1 - 7.9e-05 22.6 0.1 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_12 PF08242.12 KII84993.1 - 0.00015 22.4 0.1 0.086 13.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.22 KII84993.1 - 0.0013 19.5 0.1 0.085 13.7 0.1 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DREV PF05219.12 KII84993.1 - 0.08 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase KR PF08659.10 KII84993.1 - 0.099 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KII84993.1 - 0.11 12.9 0.0 0.48 10.9 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase_fungal PF17667.1 KII84994.1 - 1.3e-06 27.4 0.0 1.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Glyco_hydro_92 PF07971.12 KII84997.1 - 4.2e-29 101.8 0.0 4.6e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.12 KII84999.1 - 2.6e-150 501.4 2.2 3.2e-150 501.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KII84999.1 - 2.4e-63 214.2 3.7 3.8e-63 213.6 3.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Lactococcin PF04369.13 KII84999.1 - 0.011 15.8 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 0 Lactococcin-like family TRAM1 PF08390.11 KII84999.1 - 0.22 11.2 0.6 0.46 10.2 0.6 1.5 1 0 0 1 1 1 0 TRAM1-like protein PCNA_N PF00705.18 KII85000.1 - 2.1e-54 182.6 3.9 2.1e-54 182.6 3.9 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KII85000.1 - 2.7e-39 134.3 0.0 3.4e-18 66.1 0.0 3.1 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KII85000.1 - 7.4e-05 22.3 0.0 0.00051 19.6 0.0 2.1 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 KII85000.1 - 0.00024 20.2 0.1 0.003 16.7 0.1 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KII85000.1 - 0.023 13.8 3.7 2 7.5 0.0 2.7 3 0 0 3 3 3 0 Hus1-like protein Nop14 PF04147.12 KII85000.1 - 0.17 10.1 18.1 0.24 9.6 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 KII85000.1 - 1.9 8.1 16.9 3 7.5 16.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_polI_A34 PF08208.11 KII85000.1 - 2.5 8.1 21.6 5.1 7.1 21.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KII85000.1 - 9.4 4.4 14.6 13 3.9 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KII85000.1 - 9.4 4.9 6.1 13 4.4 6.1 1.2 1 0 0 1 1 1 0 Presenilin AAA PF00004.29 KII85002.1 - 8.1e-56 188.1 0.0 5.2e-43 146.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KII85002.1 - 8.2e-22 77.4 0.0 1.7e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KII85002.1 - 4.5e-16 58.4 5.0 5.9e-10 38.8 0.0 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KII85002.1 - 2.3e-10 41.1 9.6 0.00023 21.6 1.0 5.9 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 KII85002.1 - 3e-07 30.8 0.6 0.088 13.1 0.0 4.5 3 2 1 4 4 3 2 AAA domain Viral_helicase1 PF01443.18 KII85002.1 - 4.4e-06 26.6 0.0 0.097 12.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KII85002.1 - 2.4e-05 24.3 0.0 0.31 11.0 0.0 2.8 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KII85002.1 - 4.2e-05 23.3 0.0 0.0029 17.4 0.0 2.7 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KII85002.1 - 4.6e-05 23.4 0.1 0.043 13.7 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 KII85002.1 - 0.00014 21.9 0.0 0.48 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KII85002.1 - 0.00033 20.7 0.1 1 9.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KII85002.1 - 0.00034 19.9 0.2 0.16 11.2 0.0 2.6 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 KII85002.1 - 0.00046 20.4 0.0 0.052 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KII85002.1 - 0.00057 20.4 0.0 0.4 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KII85002.1 - 0.00066 18.9 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.9 KII85002.1 - 0.00082 18.7 0.0 0.26 10.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KII85002.1 - 0.0017 18.3 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain IstB_IS21 PF01695.17 KII85002.1 - 0.0018 18.1 0.1 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KII85002.1 - 0.002 17.5 0.1 0.86 8.9 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KII85002.1 - 0.0024 18.3 0.0 1.9 8.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KII85002.1 - 0.0025 17.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KII85002.1 - 0.0053 17.2 0.2 0.47 10.9 0.1 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KII85002.1 - 0.0061 15.9 0.0 4 6.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 KII85002.1 - 0.0064 16.2 1.9 0.036 13.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 KII85002.1 - 0.0068 16.3 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 NTPase Molydop_binding PF01568.21 KII85002.1 - 0.0073 16.3 0.0 0.087 12.9 0.0 2.3 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain AAA_7 PF12775.7 KII85002.1 - 0.0075 15.8 0.0 0.69 9.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 KII85002.1 - 0.012 13.6 0.0 0.018 13.0 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_24 PF13479.6 KII85002.1 - 0.013 15.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KII85002.1 - 0.014 15.3 0.0 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_3 PF07726.11 KII85002.1 - 0.014 15.3 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KII85002.1 - 0.017 14.7 2.5 8.2 6.0 0.2 4.4 4 1 0 5 5 5 0 AAA domain ABC_tran PF00005.27 KII85002.1 - 0.033 14.7 0.0 12 6.5 0.0 3.2 2 1 0 3 3 3 0 ABC transporter Cytidylate_kin2 PF13189.6 KII85002.1 - 0.045 13.9 0.0 0.59 10.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activat PF00158.26 KII85002.1 - 0.052 13.3 0.0 6.1 6.5 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 KII85002.1 - 0.067 12.9 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 KII85002.1 - 0.09 13.1 1.0 1.4 9.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 KII85002.1 - 0.1 12.5 0.0 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase cobW PF02492.19 KII85002.1 - 0.18 11.3 0.2 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KII85002.1 - 0.19 11.6 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea zf-MYND PF01753.18 KII85003.1 - 1.5e-09 37.8 14.2 3.5e-09 36.6 14.2 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII85003.1 - 0.88 9.9 17.3 0.091 13.1 12.6 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Thioredoxin PF00085.20 KII85007.1 - 2e-54 181.9 0.0 7e-26 90.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KII85007.1 - 2.3e-22 79.7 0.2 4.7e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KII85007.1 - 3e-16 59.8 0.0 3.1e-08 34.0 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KII85007.1 - 4.2e-16 59.2 0.0 5.8e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KII85007.1 - 2.3e-07 30.8 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 KII85007.1 - 3e-07 30.5 0.0 0.026 14.7 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KII85007.1 - 6.8e-07 29.5 0.1 0.36 11.2 0.0 4.4 3 2 2 5 5 5 2 Thioredoxin-like TraF PF13728.6 KII85007.1 - 2.8e-06 27.3 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KII85007.1 - 0.0054 16.5 1.6 0.82 9.4 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin Glutaredoxin PF00462.24 KII85007.1 - 0.0088 16.2 1.8 0.3 11.3 0.1 3.0 2 2 0 2 2 2 1 Glutaredoxin Redoxin PF08534.10 KII85007.1 - 0.011 15.4 0.3 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Redoxin DDE_Tnp_1_2 PF13586.6 KII85007.1 - 0.085 13.2 0.0 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain Thioredoxin_4 PF13462.6 KII85007.1 - 0.1 12.8 1.6 13 6.0 0.1 3.2 3 1 1 4 4 4 0 Thioredoxin Exo_endo_phos PF03372.23 KII85008.1 - 1.1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha-amylase PF00128.24 KII85010.1 - 2.6e-19 70.0 0.0 7.4e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KII85010.1 - 0.0011 19.1 0.1 0.0032 17.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KII85010.1 - 0.25 9.5 0.1 1.5 6.9 0.0 2.2 3 0 0 3 3 3 0 Glycosyl hydrolase family 70 Sugar_tr PF00083.24 KII85011.1 - 2.1e-82 277.4 21.6 2.4e-82 277.2 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII85011.1 - 5.9e-27 94.5 45.1 3e-23 82.3 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII85011.1 - 0.0002 19.9 2.3 0.0002 19.9 2.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Myc_target_1 PF15179.6 KII85012.1 - 0.56 10.1 2.6 1.2 9.0 1.7 2.0 1 1 0 1 1 1 0 Myc target protein 1 NAD_binding_6 PF08030.12 KII85014.1 - 1.7e-20 73.7 0.0 2e-12 47.5 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KII85014.1 - 3.7e-17 62.6 14.7 3.7e-17 62.6 14.7 2.4 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KII85014.1 - 7.4e-13 48.5 0.0 1.8e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 KII85014.1 - 0.0067 17.0 14.9 0.11 13.0 2.3 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4405) DUF2839 PF10999.8 KII85014.1 - 0.13 12.7 0.9 0.37 11.2 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Acetyltransf_3 PF13302.7 KII85015.1 - 3.4e-08 34.2 0.0 4.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII85015.1 - 2.2e-06 27.9 0.0 3.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EF-hand_6 PF13405.6 KII85016.1 - 0.021 14.7 0.2 0.076 13.0 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain MbeD_MobD PF04899.12 KII85016.1 - 0.021 14.9 0.2 1.7 8.8 0.2 2.7 2 0 0 2 2 2 0 MbeD/MobD like TBCC_N PF16752.5 KII85016.1 - 0.079 13.4 0.5 3.8 8.0 0.0 3.2 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DUF1664 PF07889.12 KII85016.1 - 0.089 12.8 1.8 3.3 7.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) YqzE PF14038.6 KII85018.1 - 1.7 8.7 4.3 2.6 8.1 0.8 2.5 2 0 0 2 2 2 0 YqzE-like protein Rrn6 PF10214.9 KII85018.1 - 8.9 4.7 7.4 13 4.1 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MFS_1 PF07690.16 KII85019.1 - 8.5e-21 74.3 40.2 2e-18 66.4 20.1 2.6 2 1 0 3 3 3 2 Major Facilitator Superfamily Sad1_UNC PF07738.13 KII85020.1 - 3e-24 85.5 0.0 5e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1690 PF07956.11 KII85020.1 - 0.1 13.0 7.5 0.18 12.2 7.5 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Spc7 PF08317.11 KII85020.1 - 0.31 9.9 6.6 0.45 9.3 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Abhydrolase_1 PF00561.20 KII85021.1 - 3.5e-35 121.9 0.0 4.8e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII85021.1 - 3.3e-12 46.2 0.0 1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII85021.1 - 2.6e-08 34.7 0.0 3.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII85021.1 - 0.0011 18.5 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 KII85021.1 - 0.0048 15.6 0.0 0.0066 15.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 KII85021.1 - 0.087 11.6 0.0 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase S28 CRAL_TRIO PF00650.20 KII85022.1 - 5.7e-32 110.6 0.0 8.7e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII85022.1 - 3.9e-19 68.6 0.3 3.9e-19 68.6 0.3 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KII85022.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Cpn60_TCP1 PF00118.24 KII85023.1 - 1.7e-155 518.4 0.7 1.9e-155 518.2 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 KII85024.1 - 3.9e-36 125.5 0.6 5.4e-36 125.0 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KII85024.1 - 0.00089 19.7 0.1 0.0018 18.7 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KII85024.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-MYND PF01753.18 KII85025.1 - 1.1e-11 44.6 17.6 2.3e-11 43.6 17.6 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KII85025.1 - 0.32 10.9 12.0 0.7 9.8 12.0 1.6 1 0 0 1 1 1 0 HIT zinc finger F-box_4 PF15966.5 KII85026.1 - 0.15 11.9 1.4 9.8 6.1 0.5 2.3 1 1 1 2 2 2 0 F-box Atg14 PF10186.9 KII85029.1 - 0.24 10.4 5.7 0.43 9.6 5.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Striatin PF08232.12 KII85029.1 - 0.51 10.9 8.7 0.85 10.2 8.7 1.3 1 0 0 1 1 1 0 Striatin family Cep57_CLD PF14073.6 KII85029.1 - 1 9.4 13.1 0.048 13.7 4.7 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 SlyX PF04102.12 KII85029.1 - 1.1 9.9 3.9 1.7 9.3 0.5 2.8 2 0 0 2 2 2 0 SlyX MIF4G PF02854.19 KII85031.1 - 6.9e-25 87.9 0.3 1.5e-24 86.8 0.1 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KII85031.1 - 2.1e-20 72.8 0.0 2.4e-19 69.4 0.0 2.6 2 0 0 2 2 2 1 MA3 domain Methyltransf_31 PF13847.6 KII85032.1 - 2.8e-16 59.7 0.0 3.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII85032.1 - 1.1e-07 32.5 0.0 1.8e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII85032.1 - 1.3e-07 32.2 0.0 3e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85032.1 - 7.3e-05 23.3 0.0 0.0002 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII85032.1 - 0.00036 20.1 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KII85032.1 - 0.00065 19.6 0.0 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII85032.1 - 0.0018 18.1 0.0 0.0037 17.0 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.10 KII85032.1 - 0.0024 17.2 0.0 0.06 12.6 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 KII85032.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KII85032.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DnaJ PF00226.31 KII85033.1 - 0.00028 20.9 0.1 0.00044 20.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KII85033.1 - 0.0032 17.5 0.0 0.0032 17.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 AAA_12 PF13087.6 KII85034.1 - 6.9e-28 97.6 0.0 1.8e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII85034.1 - 7.2e-23 81.7 3.2 2.7e-12 47.1 0.0 2.9 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KII85034.1 - 7.3e-16 58.5 0.0 1.5e-14 54.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII85034.1 - 2.3e-12 47.5 0.1 1.2e-11 45.2 0.0 2.2 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KII85034.1 - 3.6e-06 26.9 0.1 0.069 12.9 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KII85034.1 - 0.00024 20.6 0.0 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 KII85034.1 - 0.00043 20.7 0.2 0.0023 18.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ResIII PF04851.15 KII85034.1 - 0.00072 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KII85034.1 - 0.0011 18.8 0.2 0.04 13.8 0.1 2.6 2 0 0 2 2 2 1 Helicase NB-ARC PF00931.22 KII85034.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KII85034.1 - 0.011 16.0 0.1 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KII85034.1 - 0.021 15.2 0.1 0.046 14.1 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KII85034.1 - 0.035 14.6 0.5 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KII85034.1 - 0.037 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KII85034.1 - 0.05 13.1 0.2 0.39 10.2 0.0 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KII85034.1 - 0.071 12.3 0.0 0.21 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KII85034.1 - 0.078 12.9 0.2 0.43 10.6 0.0 2.2 2 1 0 2 2 2 0 Flavivirus DEAD domain RAP1 PF07218.11 KII85035.1 - 2.2 6.4 12.6 2.5 6.3 12.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Citrate_synt PF00285.21 KII85036.1 - 3.8e-109 365.1 0.0 4.6e-109 364.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain AAA_12 PF13087.6 KII85037.1 - 3.5e-13 49.6 0.0 3.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII85038.1 - 1.6e-22 80.6 0.2 7.3e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KII85038.1 - 1.1e-16 61.2 0.0 4.2e-16 59.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII85038.1 - 3.5e-13 50.1 0.3 1.6e-12 48.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KII85038.1 - 8.4e-05 22.4 0.1 0.035 13.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KII85038.1 - 9.8e-05 22.7 0.0 0.00046 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KII85038.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KII85038.1 - 0.00043 19.5 0.0 0.00088 18.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 KII85038.1 - 0.00043 20.8 0.1 0.038 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 KII85038.1 - 0.0005 19.6 0.1 0.0053 16.2 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 KII85038.1 - 0.00051 20.5 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 KII85038.1 - 0.0009 19.1 0.1 0.005 16.7 0.1 2.1 1 1 0 1 1 1 1 Helicase AAA PF00004.29 KII85038.1 - 0.0042 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KII85038.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 KII85038.1 - 0.0098 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KII85038.1 - 0.013 15.7 0.1 0.055 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KII85038.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.12 KII85038.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KII85038.1 - 0.047 13.4 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KII85038.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KII85038.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 KII85038.1 - 0.099 13.2 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KII85038.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KII85038.1 - 0.12 12.6 0.0 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 KII85038.1 - 0.14 11.7 0.1 0.9 9.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF2713 PF10897.8 KII85038.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Pcc1 PF09341.10 KII85039.1 - 8.2e-23 80.3 1.1 9.2e-23 80.2 1.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_M24 PF00557.24 KII85040.1 - 4.8e-15 55.8 0.1 6.1e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_25 PF13649.6 KII85041.1 - 1.2e-15 58.0 0.0 2.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85041.1 - 1.1e-11 45.3 0.0 2.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII85041.1 - 1.7e-09 37.4 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KII85041.1 - 2.3e-08 34.0 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII85041.1 - 8.5e-08 32.8 0.0 2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII85041.1 - 4.4e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KII85041.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 KII85041.1 - 0.00023 21.4 0.0 0.001 19.2 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KII85041.1 - 0.0005 19.6 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KII85041.1 - 0.00063 19.1 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KII85041.1 - 0.0056 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KII85041.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KII85041.1 - 0.027 14.3 0.0 0.38 10.6 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase NDUF_B8 PF05821.11 KII85042.1 - 2.2e-06 27.7 0.1 3.5e-06 27.0 0.1 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) XPG_N PF00752.17 KII85043.1 - 4.2e-29 101.0 0.0 1.3e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KII85043.1 - 7.3e-27 93.6 0.0 2.3e-26 92.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KII85043.1 - 0.0096 15.4 0.0 0.021 14.3 0.0 1.5 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KII85043.1 - 0.013 16.1 0.0 0.29 11.7 0.0 2.9 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DUF5320 PF17253.2 KII85043.1 - 4.5 8.4 7.5 0.74 10.9 3.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PH PF00169.29 KII85044.1 - 6.7e-05 23.3 0.0 0.0013 19.2 0.0 2.6 3 0 0 3 3 3 1 PH domain CENP-B_dimeris PF09026.10 KII85044.1 - 0.35 11.3 7.2 0.82 10.1 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 KII85044.1 - 1.3 8.7 7.3 6.1 6.6 7.3 2.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KII85044.1 - 7.8 5.7 10.6 15 4.8 10.6 1.4 1 0 0 1 1 1 0 NOA36 protein CtaG_Cox11 PF04442.14 KII85045.1 - 1.3e-57 194.1 0.0 1.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.31 KII85046.1 - 4.6e-15 55.5 1.2 4.6e-15 55.5 1.2 1.8 2 0 0 2 2 2 1 DnaJ domain Sporozoite_P67 PF05642.11 KII85047.1 - 0.86 7.6 7.4 1 7.3 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RMI1_N PF08585.12 KII85048.1 - 1.9e-29 103.0 0.0 2.5e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Carn_acyltransf PF00755.20 KII85049.1 - 5.7e-169 563.5 0.0 6.5e-169 563.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_11 PF13086.6 KII85050.1 - 1.9e-25 90.1 0.2 5.6e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 KII85050.1 - 1.2e-18 67.5 0.0 1.9e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII85050.1 - 8e-15 55.1 0.0 1.7e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII85050.1 - 8.6e-13 48.9 0.0 2.7e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII85050.1 - 5.4e-08 33.4 0.0 1e-07 32.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KII85050.1 - 2.3e-06 27.7 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KII85050.1 - 2.2e-05 24.4 0.0 8.1e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KII85050.1 - 0.0013 18.3 0.0 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KII85050.1 - 0.0018 17.7 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KII85050.1 - 0.0019 18.5 0.0 0.0075 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KII85050.1 - 0.0022 17.8 0.1 0.0064 16.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 KII85050.1 - 0.0041 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.9 KII85050.1 - 0.0045 16.3 0.1 0.025 13.8 0.1 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 KII85050.1 - 0.0046 16.4 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein ATPase_2 PF01637.18 KII85050.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Herpes_ori_bp PF02399.15 KII85050.1 - 0.022 12.9 0.0 0.033 12.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Rad17 PF03215.15 KII85050.1 - 0.022 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KII85050.1 - 0.025 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KII85050.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KII85050.1 - 0.046 13.7 0.1 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KII85050.1 - 0.052 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KII85050.1 - 0.13 11.2 0.3 0.4 9.5 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KII85050.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KII85050.1 - 0.13 11.9 0.1 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KII85050.1 - 0.13 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_24 PF13479.6 KII85050.1 - 0.14 11.9 0.2 0.33 10.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KII85050.1 - 0.16 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Med26 PF08711.11 KII85051.1 - 1.7e-08 34.3 0.0 1.7e-08 34.3 0.0 2.5 4 0 0 4 4 4 1 TFIIS helical bundle-like domain Seadorna_VP6 PF07407.11 KII85051.1 - 0.063 12.2 0.2 0.085 11.8 0.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Phosphonate-bd PF12974.7 KII85053.1 - 5.4e-07 29.4 0.0 7.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 KII85053.1 - 0.00028 20.4 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KII85053.1 - 0.00068 19.6 0.0 0.00096 19.2 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 KII85053.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 KII85053.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Yip1 PF04893.17 KII85054.1 - 4.2e-13 49.4 18.6 6e-13 48.9 18.6 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KII85054.1 - 0.12 12.2 11.6 0.17 11.6 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AAA PF00004.29 KII85055.1 - 7.8e-42 142.8 0.0 1.3e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KII85055.1 - 9.3e-11 41.5 0.0 2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KII85055.1 - 6.8e-10 38.6 0.9 1.3e-09 37.6 0.9 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KII85055.1 - 5.2e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KII85055.1 - 4.1e-05 22.9 0.0 7.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KII85055.1 - 4.4e-05 23.8 0.2 0.029 14.6 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 KII85055.1 - 0.00022 21.2 0.2 0.0013 18.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII85055.1 - 0.00026 21.4 0.2 0.01 16.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KII85055.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 KII85055.1 - 0.0041 16.7 0.3 0.02 14.6 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KII85055.1 - 0.0051 16.2 0.1 0.18 11.1 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.6 KII85055.1 - 0.0065 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KII85055.1 - 0.0067 16.3 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KII85055.1 - 0.011 16.3 0.9 0.018 15.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KII85055.1 - 0.016 15.5 0.3 0.096 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KII85055.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KII85055.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KII85055.1 - 0.079 12.9 0.1 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 KII85055.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KII85055.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KII85055.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KII85055.1 - 0.1 12.2 0.5 2.9 7.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII85055.1 - 0.12 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KII85055.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KII85055.1 - 0.2 11.3 0.4 0.46 10.2 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KII85055.1 - 1.5 8.5 4.9 0.34 10.6 0.2 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KII85056.1 - 2.7e-08 33.9 0.0 2.7e-08 33.9 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KII85056.1 - 2e-06 27.3 0.1 2e-06 27.3 0.1 2.7 3 1 1 4 4 3 1 AIG1 family FeoB_N PF02421.18 KII85056.1 - 0.00033 20.2 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 KII85056.1 - 0.00034 20.0 0.0 0.00034 20.0 0.0 2.9 3 1 0 3 3 3 1 Septin AAA_24 PF13479.6 KII85056.1 - 0.0004 20.2 0.1 0.77 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII85056.1 - 0.0009 18.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KII85056.1 - 0.003 17.5 0.2 0.003 17.5 0.2 3.1 3 1 1 4 4 4 1 RsgA GTPase ABC_tran PF00005.27 KII85056.1 - 0.0032 18.0 17.8 0.0038 17.8 0.0 3.8 3 2 0 3 3 3 1 ABC transporter Dynamin_N PF00350.23 KII85056.1 - 0.0058 16.7 0.1 0.0058 16.7 0.1 4.7 3 2 1 4 4 3 2 Dynamin family T2SSE PF00437.20 KII85056.1 - 0.014 14.4 10.3 0.022 13.8 0.1 3.0 2 1 1 3 3 3 0 Type II/IV secretion system protein Pox_A32 PF04665.12 KII85056.1 - 0.029 13.9 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein IIGP PF05049.13 KII85056.1 - 0.037 13.1 9.1 0.038 13.1 0.0 3.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) Microtub_bd PF16796.5 KII85056.1 - 0.043 13.8 2.0 8 6.4 0.1 2.8 1 1 1 2 2 2 0 Microtubule binding G-alpha PF00503.20 KII85056.1 - 0.045 12.9 5.9 0.43 9.7 0.0 3.2 2 1 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.10 KII85056.1 - 0.048 13.1 0.0 0.048 13.1 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KII85056.1 - 0.052 13.8 7.3 0.89 9.8 0.0 3.6 3 1 0 3 3 2 0 AAA domain Peptidase_M14 PF00246.24 KII85056.1 - 0.067 13.0 0.5 0.11 12.2 0.5 1.3 1 0 0 1 1 1 0 Zinc carboxypeptidase FtsK_SpoIIIE PF01580.18 KII85056.1 - 0.078 12.3 15.9 0.079 12.3 0.2 3.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KII85056.1 - 0.09 12.5 0.8 5.8 6.7 0.2 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation V_ATPase_I PF01496.19 KII85056.1 - 0.19 9.6 16.0 0.26 9.1 16.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_7 PF12775.7 KII85056.1 - 0.8 9.2 2.7 13 5.2 0.2 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region BshC PF10079.9 KII85056.1 - 1.1 7.9 16.7 1.5 7.5 16.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Pox_A_type_inc PF04508.12 KII85056.1 - 1.2 9.2 7.6 8.6 6.4 0.0 3.4 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat AAA_18 PF13238.6 KII85056.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.9 3 1 0 3 3 2 0 AAA domain DUF4407 PF14362.6 KII85056.1 - 1.6 8.0 17.9 2.5 7.4 17.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_16 PF13191.6 KII85056.1 - 2.3 8.6 16.4 2.5 8.4 0.0 4.0 3 1 0 3 3 2 0 AAA ATPase domain DUF4776 PF16003.5 KII85056.1 - 2.8 6.9 13.8 3.8 6.4 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SAPS PF04499.15 KII85056.1 - 3.5 6.3 15.3 5.5 5.7 15.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ArlS_N PF18719.1 KII85056.1 - 6 7.1 10.2 7.7 6.7 2.6 3.4 3 1 1 4 4 3 0 ArlS sensor domain CSN5_C PF18323.1 KII85056.1 - 8.3 7.4 12.0 19 6.2 4.7 2.8 1 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Asp-B-Hydro_N PF05279.11 KII85056.1 - 9.5 6.2 22.3 14 5.6 22.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MMR_HSR1 PF01926.23 KII85057.1 - 1.3e-05 25.3 0.6 3e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KII85057.1 - 0.0022 17.3 0.0 0.0022 17.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KII85057.1 - 0.0084 16.0 0.7 0.028 14.3 0.7 1.9 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KII85057.1 - 0.015 14.6 0.1 0.081 12.2 0.1 2.2 1 1 0 1 1 1 0 Septin Dynamin_N PF00350.23 KII85057.1 - 0.026 14.6 0.0 0.026 14.6 0.0 3.5 2 2 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 KII85057.1 - 0.045 13.3 0.2 0.66 9.5 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B FapA PF03961.13 KII85057.1 - 0.12 11.0 5.0 0.15 10.6 5.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ING PF12998.7 KII85057.1 - 1.1 9.9 6.7 5.9 7.5 1.1 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Exonuc_VII_L PF02601.15 KII85057.1 - 4.8 6.7 14.2 7.1 6.1 14.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C2H2 PF00096.26 KII85061.1 - 4.4e-12 45.7 13.7 0.00039 20.7 0.7 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85061.1 - 3.3e-09 36.8 12.9 0.012 16.4 0.5 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII85061.1 - 4e-09 36.5 17.4 2.8e-05 24.3 0.3 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 KII85061.1 - 0.00045 20.1 7.3 0.024 14.7 0.1 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KII85061.1 - 0.0076 16.5 3.8 0.018 15.3 3.2 1.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 KII85061.1 - 0.0084 16.5 6.5 1.3 9.5 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KII85061.1 - 0.0086 16.7 9.6 0.23 12.1 2.6 2.9 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KII85061.1 - 0.072 13.2 3.8 3.9 7.6 0.4 2.8 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 KII85061.1 - 0.38 11.1 8.8 3.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KII85061.1 - 0.58 10.0 5.4 21 5.0 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-AN1 PF01428.16 KII85061.1 - 6.7 7.0 12.9 3.6 7.8 4.1 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger RAI1 PF08652.11 KII85063.1 - 2.7e-21 75.5 0.0 4.6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease TPR_12 PF13424.6 KII85066.1 - 2.3e-30 104.7 16.4 4.5e-09 36.5 0.3 5.2 3 2 3 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KII85066.1 - 4.1e-18 64.0 18.4 0.074 13.2 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat SNAP PF14938.6 KII85066.1 - 3.1e-16 59.6 13.0 5.7e-09 35.8 2.2 3.1 1 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP SHNi-TPR PF10516.9 KII85066.1 - 3e-11 42.6 3.0 0.0046 16.4 0.0 5.7 5 0 0 5 5 5 2 SHNi-TPR TPR_1 PF00515.28 KII85066.1 - 7.8e-10 38.1 17.5 0.0016 18.1 0.2 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII85066.1 - 1.1e-07 31.4 11.7 0.37 10.5 0.1 7.4 7 0 0 7 7 7 2 TPR repeat TPR_10 PF13374.6 KII85066.1 - 3.9e-07 29.7 3.9 0.39 10.7 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII85066.1 - 8.3e-07 29.6 0.5 7.6 7.3 0.0 5.8 3 1 3 6 6 6 0 Tetratricopeptide repeat HsbA PF12296.8 KII85066.1 - 1.6e-05 25.3 7.0 0.19 12.2 0.0 4.3 3 1 2 5 5 4 2 Hydrophobic surface binding protein A TPR_7 PF13176.6 KII85066.1 - 2.3e-05 24.1 1.4 0.43 10.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII85066.1 - 3.7e-05 23.6 13.6 0.085 13.1 0.3 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KII85066.1 - 5.4e-05 23.3 16.5 0.13 12.5 0.9 6.3 4 2 3 7 7 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Vps5 PF09325.10 KII85066.1 - 6.2e-05 22.7 4.7 0.029 13.9 2.2 3.7 2 2 0 2 2 2 1 Vps5 C terminal like TPR_19 PF14559.6 KII85066.1 - 8.6e-05 23.0 17.1 2.1 8.9 2.6 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KII85066.1 - 0.0013 18.2 6.6 0.0013 18.2 6.6 3.0 1 1 2 3 3 3 2 MalT-like TPR region DUF724 PF05266.14 KII85066.1 - 0.0047 16.8 3.7 2.6 7.8 0.1 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF724) TPR_3 PF07720.12 KII85066.1 - 0.013 15.5 1.1 0.11 12.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 KII85066.1 - 0.013 15.2 6.8 1.4 8.6 0.2 3.6 1 1 0 2 2 2 0 26S proteasome subunit RPN7 RIG-I_C-RD PF11648.8 KII85066.1 - 0.015 15.5 0.4 62 3.9 0.0 5.0 2 2 4 6 6 6 0 C-terminal domain of RIG-I rRNA_proc-arch PF13234.6 KII85066.1 - 0.047 13.6 1.7 10 5.9 0.2 2.8 2 0 0 2 2 2 0 rRNA-processing arch domain EF-hand_2 PF09068.11 KII85066.1 - 0.048 13.8 2.3 0.51 10.5 0.1 3.2 2 1 0 2 2 2 0 EF hand DUF3763 PF12592.8 KII85066.1 - 0.1 12.7 13.6 19 5.4 0.4 6.0 7 0 0 7 7 7 0 Protein of unknown function (DUF3763) TPR_17 PF13431.6 KII85066.1 - 1.5 9.4 8.6 70 4.1 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Cor1 PF04803.12 KII85066.1 - 1.6 8.9 11.3 1.1 9.5 1.6 3.7 2 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF148 PF02520.17 KII85066.1 - 2.5 8.3 5.9 13 6.0 0.2 3.4 4 0 0 4 4 2 0 Domain of unknown function DUF148 zf-AD PF07776.15 KII85066.1 - 3.1 8.1 5.2 27 5.1 0.0 4.4 5 1 0 5 5 4 0 Zinc-finger associated domain (zf-AD) CFEM PF05730.11 KII85067.1 - 3 8.0 12.5 31 4.8 9.2 2.8 2 1 0 2 2 2 0 CFEM domain Whi5 PF08528.11 KII85069.1 - 4.9e-05 22.8 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Apt1 PF10351.9 KII85069.1 - 5.7 5.7 6.2 8.3 5.1 6.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SpoIIIAH PF12685.7 KII85069.1 - 6.2 6.6 6.0 37 4.1 6.0 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein IGF2_C PF08365.11 KII85070.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Pkinase PF00069.25 KII85071.1 - 0.00027 20.4 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KII85071.1 - 0.011 14.6 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SUR7 PF06687.12 KII85072.1 - 1.4e-09 37.9 14.6 6.2e-05 22.7 0.2 2.1 1 1 1 2 2 2 2 SUR7/PalI family Sugar_tr PF00083.24 KII85074.1 - 9.5e-113 377.4 27.8 1.1e-112 377.2 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII85074.1 - 9.3e-24 84.0 35.4 9.3e-24 84.0 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 KII85075.1 - 9e-65 219.7 0.0 1.1e-64 219.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S28 PF05577.12 KII85075.1 - 0.067 12.0 0.1 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 Serine carboxypeptidase S28 ECH_1 PF00378.20 KII85076.1 - 4.5e-34 117.9 0.0 5.6e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII85076.1 - 1.5e-13 50.9 0.0 1.9e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TauD PF02668.16 KII85078.1 - 2e-52 178.6 1.2 2.7e-52 178.2 1.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MIT PF04212.18 KII85079.1 - 0.0039 17.2 0.7 0.0079 16.2 0.7 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 KII85079.1 - 0.03 14.0 0.5 0.053 13.2 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4164 PF13747.6 KII85079.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) TPR_2 PF07719.17 KII85079.1 - 0.14 12.3 0.7 0.32 11.2 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_79C PF16862.5 KII85080.1 - 9.2e-21 74.7 2.3 1.1e-20 74.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Herpes_UL4 PF03277.13 KII85080.1 - 0.08 12.6 0.6 0.23 11.1 0.6 1.7 1 0 0 1 1 1 0 Herpesvirus UL4 family GATA PF00320.27 KII85081.1 - 2.9e-15 55.6 3.8 6e-15 54.6 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PRiA4_ORF3 PF07929.11 KII85084.1 - 2e-27 96.0 0.0 3.4e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 KII85084.1 - 4.7e-12 45.8 8.9 8e-12 45.0 8.9 1.4 1 0 0 1 1 1 1 MYND finger Actin PF00022.19 KII85085.1 - 4.1e-39 134.4 0.0 4.7e-34 117.7 0.0 2.8 3 0 0 3 3 3 2 Actin IGF2_C PF08365.11 KII85085.1 - 0.088 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide DUF4165 PF13752.6 KII85086.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Exonuc_VII_L PF02601.15 KII85087.1 - 0.018 14.7 0.2 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mito_carr PF00153.27 KII85088.1 - 5.2e-59 196.2 0.2 9.2e-23 80.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_16 PF10294.9 KII85089.1 - 1.3e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KII85089.1 - 0.04 13.7 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Arrestin_N PF00339.29 KII85090.1 - 9.4e-10 38.7 0.3 2.9e-07 30.6 0.2 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.15 KII85090.1 - 0.26 10.3 0.0 0.42 9.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Helicase_C PF00271.31 KII85091.1 - 3.2e-18 66.1 0.0 4.7e-17 62.3 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII85091.1 - 1.3e-16 60.9 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII85091.1 - 1.5e-10 41.3 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII85091.1 - 0.0023 18.3 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arrestin_N PF00339.29 KII85093.1 - 7.8e-07 29.2 0.0 0.00026 21.0 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Nucleoporin_FG PF13634.6 KII85094.1 - 2.6e-23 82.7 96.0 1.2e-10 42.0 32.5 3.7 2 1 1 3 3 3 3 Nucleoporin FG repeat region DUF1944 PF09175.10 KII85094.1 - 0.0086 15.9 0.1 0.37 10.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1944) AceK PF06315.11 KII85094.1 - 0.03 12.8 1.1 0.041 12.4 1.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) V_ATPase_I PF01496.19 KII85094.1 - 0.091 10.7 2.4 0.081 10.8 1.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 KII85094.1 - 0.54 10.6 6.5 10 6.5 0.1 3.6 2 2 2 4 4 4 0 Uncharacterized conserved protein Nucleoporin_FG2 PF15967.5 KII85094.1 - 1.9 6.9 63.2 13 4.1 63.2 3.2 1 1 0 1 1 1 0 Nucleoporin FG repeated region USP8_interact PF08941.10 KII85095.1 - 0.0024 17.7 0.1 0.0062 16.4 0.0 1.6 2 0 0 2 2 2 1 USP8 interacting Val_tRNA-synt_C PF10458.9 KII85095.1 - 2.2 8.6 5.1 2.8 8.3 2.1 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Mitofilin PF09731.9 KII85096.1 - 8.2e-110 368.5 17.3 1.4e-108 364.5 17.3 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Peptidase_M49 PF03571.15 KII85096.1 - 0.017 13.5 0.6 0.025 12.9 0.6 1.1 1 0 0 1 1 1 0 Peptidase family M49 Rb_C PF08934.10 KII85096.1 - 0.34 10.7 1.9 0.91 9.3 1.9 1.7 1 0 0 1 1 1 0 Rb C-terminal domain DUF1664 PF07889.12 KII85096.1 - 6.9 6.7 8.1 3 7.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ATG22 PF11700.8 KII85097.1 - 1.7e-123 412.7 21.6 2e-123 412.5 21.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF350 PF03994.14 KII85097.1 - 0.088 13.0 5.3 0.25 11.5 0.1 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF350) DUF962 PF06127.11 KII85097.1 - 0.14 12.3 0.0 0.14 12.3 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) DUF2678 PF10856.8 KII85097.1 - 0.73 9.8 5.0 20 5.2 3.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Trehalase PF01204.18 KII85098.1 - 4e-169 563.7 0.0 4.9e-169 563.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KII85098.1 - 8e-15 54.3 0.1 1.4e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Lipase_3 PF01764.25 KII85099.1 - 1.2e-07 31.7 0.0 5.4e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 KII85099.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 KII85099.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ctf8 PF09696.10 KII85100.1 - 6.2e-16 59.0 0.1 1.4e-14 54.6 0.1 2.0 1 1 0 1 1 1 1 Ctf8 Stm1_N PF09598.10 KII85102.1 - 9.2 7.2 11.1 41 5.1 0.2 2.8 2 0 0 2 2 2 0 Stm1 F-box-like PF12937.7 KII85103.1 - 1.2e-10 41.1 1.2 2e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF4611 PF15387.6 KII85103.1 - 0.061 13.5 3.2 0.13 12.5 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GCIP PF13324.6 KII85103.1 - 0.69 9.5 2.1 1 8.9 2.1 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 KII85103.1 - 1.2 8.9 5.1 2 8.1 5.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 KII85103.1 - 1.5 9.0 7.0 11 6.2 5.9 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Methyltransf_28 PF02636.17 KII85108.1 - 1.4e-66 224.8 0.0 1.8e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.6 KII85108.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain eIF-6 PF01912.18 KII85109.1 - 7.9e-83 276.7 0.3 7.9e-83 276.7 0.3 1.6 2 0 0 2 2 2 1 eIF-6 family AhpC-TSA_2 PF13911.6 KII85110.1 - 3.4e-14 52.9 0.0 6.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KII85110.1 - 4.2e-09 36.4 0.0 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII85110.1 - 7.9e-07 28.9 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin F-box-like PF12937.7 KII85111.1 - 0.00024 20.9 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 KII85111.1 - 0.6 10.9 7.8 2.6 8.9 0.6 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat Kelch_4 PF13418.6 KII85112.1 - 7.9e-24 83.4 10.4 1.9e-07 31.0 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KII85112.1 - 2.4e-17 62.2 4.4 4e-06 26.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 KII85112.1 - 6.6e-17 61.1 6.8 6.2e-05 22.9 0.0 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 KII85112.1 - 3.3e-15 55.9 19.3 1.8e-05 24.9 0.1 6.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KII85112.1 - 4.2e-15 55.4 14.8 2.1e-06 27.8 0.2 5.5 3 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 KII85112.1 - 9.8e-11 41.2 9.4 0.00011 22.0 0.4 5.7 6 0 0 6 6 6 2 Kelch motif SKG6 PF08693.10 KII85112.1 - 0.067 12.6 0.0 0.067 12.6 0.0 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Bac_rhamnosid6H PF17389.2 KII85113.1 - 7.4e-16 58.3 0.1 1.2e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KII85113.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KII85113.1 - 0.00014 20.9 0.2 0.0002 20.3 0.2 1.2 1 0 0 1 1 1 1 Trehalase dsrm PF00035.26 KII85113.1 - 0.21 12.3 0.0 0.6 10.9 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Aa_trans PF01490.18 KII85114.1 - 2.2e-81 273.6 34.4 2.6e-81 273.4 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAM199X PF15814.5 KII85114.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X PTPlike_phytase PF14566.6 KII85117.1 - 2.7e-138 456.4 0.0 6.7e-47 159.5 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 KII85117.1 - 2.9e-06 27.0 0.0 0.017 14.7 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 KII85117.1 - 0.00015 21.6 0.0 0.68 9.8 0.0 4.3 5 0 0 5 5 5 1 Dual specificity phosphatase, catalytic domain AIP3 PF03915.13 KII85117.1 - 0.037 13.1 1.4 0.073 12.1 0.0 2.1 3 0 0 3 3 3 0 Actin interacting protein 3 TFIIE-A_C PF11521.8 KII85117.1 - 0.16 12.3 0.0 59 4.1 0.0 3.4 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha VSP PF03302.13 KII85118.1 - 0.00061 18.8 11.0 0.0009 18.2 11.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein CD99L2 PF12301.8 KII85118.1 - 0.068 13.5 10.2 0.22 11.8 10.3 2.1 1 1 0 1 1 1 0 CD99 antigen like protein 2 VTC PF09359.10 KII85119.1 - 5e-93 311.5 2.1 5.9e-93 311.3 0.0 2.1 3 0 0 3 3 3 1 VTC domain DUF202 PF02656.15 KII85119.1 - 1.2e-09 38.5 2.9 1.2e-09 38.5 2.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KII85119.1 - 8.1e-08 32.6 35.4 0.0005 20.1 0.1 4.5 2 2 2 4 4 4 3 SPX domain Clc-like PF07062.12 KII85119.1 - 0.088 12.3 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 Clc-like Gtr1_RagA PF04670.12 KII85120.1 - 7e-50 169.5 0.0 9.8e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KII85120.1 - 2.5e-05 23.8 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII85120.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KII85120.1 - 0.0045 16.4 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KII85120.1 - 0.0086 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KII85120.1 - 0.035 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KII85120.1 - 0.2 10.8 1.2 0.46 9.6 1.2 1.4 1 1 0 1 1 1 0 G-protein alpha subunit F-box-like PF12937.7 KII85121.1 - 1.7e-08 34.2 1.7 1.7e-08 34.2 1.7 2.1 2 0 0 2 2 2 1 F-box-like CTP_transf_like PF01467.26 KII85122.1 - 0.031 14.5 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase-like GMC_oxred_N PF00732.19 KII85123.1 - 1e-72 245.0 0.0 1.4e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII85123.1 - 3.9e-37 128.0 0.3 6.6e-37 127.2 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII85123.1 - 4.6e-06 26.0 0.7 0.0021 17.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KII85123.1 - 1.7e-05 24.0 0.5 5.7e-05 22.3 0.4 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII85123.1 - 0.00017 21.8 0.2 0.00062 19.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII85123.1 - 0.00082 18.7 0.1 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KII85123.1 - 0.0053 16.4 4.4 0.032 13.8 4.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII85123.1 - 0.051 12.8 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gly_kinase PF02595.15 KII85123.1 - 0.072 12.1 0.6 0.35 9.8 0.3 2.0 2 0 0 2 2 2 0 Glycerate kinase family HI0933_like PF03486.14 KII85123.1 - 0.18 10.5 0.2 0.28 9.8 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein RhoGAP PF00620.27 KII85124.1 - 2.5e-38 131.3 0.0 3.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 KII85124.1 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) ORC_WH_C PF18137.1 KII85124.1 - 0.57 10.3 5.1 1.5 8.9 0.0 2.7 2 1 1 3 3 3 0 Origin recognition complex winged helix C-terminal Glyco_hydro_17 PF00332.18 KII85125.1 - 5.9e-12 45.8 5.8 1.8e-09 37.7 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Drf_GBD PF06371.13 KII85126.1 - 8.7e-15 54.8 0.0 1.1e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF823 PF05689.11 KII85126.1 - 0.037 13.8 0.1 0.061 13.1 0.1 1.2 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Fungal_trans_2 PF11951.8 KII85127.1 - 1.8e-49 168.6 0.0 3.5e-49 167.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85127.1 - 2.5e-05 24.3 8.8 2.5e-05 24.3 8.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KII85128.1 - 9.7e-35 120.1 1.8 2.4e-34 118.8 1.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85128.1 - 0.00014 21.9 8.7 0.00028 20.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 KII85129.1 - 2.4e-32 111.6 0.8 1.8e-17 63.7 0.3 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 KII85129.1 - 6.7e-12 45.8 14.3 1.1e-05 25.7 6.0 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 KII85129.1 - 2.3e-09 37.3 0.1 0.00011 22.3 0.1 3.8 3 1 0 3 3 3 2 PH domain PH_8 PF15409.6 KII85129.1 - 3.6e-07 30.4 1.5 4.4e-05 23.7 0.3 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KII85129.1 - 0.00014 22.2 0.2 0.31 11.4 0.4 2.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 KII85129.1 - 0.00092 19.1 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 KII85129.1 - 0.0025 18.1 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_4 PF15404.6 KII85129.1 - 0.066 13.0 0.1 0.95 9.2 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain Mcp5_PH PF12814.7 KII85129.1 - 0.3 11.2 2.6 10 6.3 0.0 2.9 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology ACBP PF00887.19 KII85130.1 - 5.5e-29 100.2 0.9 5.5e-29 100.2 0.9 1.3 2 0 0 2 2 2 1 Acyl CoA binding protein FAD_binding_3 PF01494.19 KII85133.1 - 2.4e-07 30.4 0.0 4.2e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KII85133.1 - 4.3e-07 29.6 0.4 7.5e-05 22.2 0.1 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII85133.1 - 7.7e-07 29.3 0.5 1.9e-06 28.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII85133.1 - 1.9e-06 27.7 0.0 0.0004 20.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII85133.1 - 6.9e-05 22.1 0.1 0.00024 20.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KII85133.1 - 0.00017 20.9 0.1 0.0014 17.9 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII85133.1 - 0.0061 17.1 0.2 0.026 15.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII85133.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII85133.1 - 0.023 13.4 0.1 0.038 12.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KII85133.1 - 0.058 12.7 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TetR_C_13 PF16925.5 KII85133.1 - 0.17 11.8 0.1 0.46 10.4 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain mRNA_decap_C PF16741.5 KII85133.1 - 0.2 11.0 0.1 0.44 9.9 0.1 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus GIDA PF01134.22 KII85133.1 - 0.38 9.8 0.7 0.59 9.1 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1729 PF08354.10 KII85134.1 - 2.5e-149 497.0 0.0 4.2e-149 496.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 KII85134.1 - 2.5e-74 249.3 0.5 6.8e-74 247.9 0.1 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 KII85134.1 - 1.8e-73 247.8 0.1 1.5e-71 241.5 0.0 3.5 4 0 0 4 4 4 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 KII85134.1 - 2.9e-73 245.5 0.0 6e-73 244.5 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 KII85134.1 - 4.9e-45 152.9 0.0 1.1e-44 151.8 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 KII85134.1 - 2.9e-32 112.3 0.3 6.4e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KII85134.1 - 3.9e-27 95.4 0.2 7.8e-27 94.5 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 KII85134.1 - 5.8e-26 91.0 0.3 1.4e-25 89.8 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KII85134.1 - 1.9e-25 88.8 0.1 8e-25 86.8 0.0 2.1 2 0 0 2 2 2 1 MaoC like domain Ketoacyl-synt_C PF02801.22 KII85134.1 - 3.7e-15 56.0 0.0 1e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KII85134.1 - 1.3e-13 51.1 0.0 2.9e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily MaoC_dehydrat_N PF13452.6 KII85134.1 - 2.8e-12 46.9 0.1 2e-11 44.1 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 KII85134.1 - 1.7e-06 27.7 0.0 7.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 KII85134.1 - 0.049 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain F-box-like PF12937.7 KII85135.1 - 1.1e-08 34.8 0.6 1.1e-08 34.8 0.6 2.9 3 0 0 3 3 3 1 F-box-like TPR_1 PF00515.28 KII85136.1 - 2.7e-08 33.3 10.9 0.027 14.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII85136.1 - 4.1e-05 23.7 1.3 0.23 11.9 0.6 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII85136.1 - 0.00012 22.5 7.7 0.0054 17.2 4.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII85136.1 - 0.00018 21.4 16.0 0.2 11.9 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII85136.1 - 0.00072 19.2 11.4 0.0043 16.7 1.7 3.1 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 KII85136.1 - 0.0034 18.1 4.5 3.7 8.6 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII85136.1 - 0.0067 17.1 5.5 0.0067 17.1 5.5 3.2 2 2 1 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII85136.1 - 0.034 14.4 5.0 0.3 11.4 0.8 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII85136.1 - 0.38 10.9 5.0 0.27 11.4 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KII85136.1 - 0.62 10.3 4.8 0.27 11.5 1.7 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KII85136.1 - 0.95 9.8 12.1 20 5.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DnaJ_C PF01556.18 KII85137.1 - 2.6e-23 82.7 0.0 5.8e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KII85137.1 - 8.4e-18 64.3 1.7 2.3e-17 62.9 1.7 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KII85139.1 - 8.2e-38 129.8 0.1 1.1e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KII85139.1 - 9.8e-14 51.2 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF202 PF02656.15 KII85140.1 - 1.4e-13 51.0 2.6 7.9e-13 48.7 2.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Insulin_TMD PF17870.1 KII85140.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5084 PF16894.5 KII85140.1 - 0.06 13.8 0.6 0.095 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) Transcrip_reg PF01709.20 KII85141.1 - 2.2e-70 236.8 0.0 2.5e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Amidase PF01425.21 KII85142.1 - 4e-86 289.7 0.0 3e-85 286.9 0.0 2.2 2 1 0 2 2 2 1 Amidase zf-MYND PF01753.18 KII85143.1 - 1.9e-07 31.0 8.9 3.7e-07 30.1 8.9 1.5 1 0 0 1 1 1 1 MYND finger NYN PF01936.18 KII85144.1 - 3.6e-19 69.7 0.0 6.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 NYN domain zf-C2H2 PF00096.26 KII85145.1 - 1.8e-08 34.4 10.6 0.00052 20.3 5.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85145.1 - 0.00029 21.4 9.6 0.014 16.1 4.2 2.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf_ZIC PF18366.1 KII85145.1 - 0.0082 16.2 0.6 1.1 9.5 0.7 2.2 1 1 1 2 2 2 2 Zic proteins zinc finger domain zf-MYND PF01753.18 KII85146.1 - 1.6e-07 31.3 10.3 2.5e-07 30.7 10.3 1.3 1 0 0 1 1 1 1 MYND finger His_Phos_2 PF00328.22 KII85147.1 - 1.9e-37 129.5 0.0 2.4e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.28 KII85148.1 - 1.2e-11 44.8 0.5 1.6e-11 44.4 0.5 1.2 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.22 KII85149.1 - 4.5e-46 157.6 18.7 1.1e-43 149.7 18.7 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol3_delta2 PF13177.6 KII85150.1 - 1.3e-12 47.8 0.3 2.7e-12 46.8 0.3 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KII85150.1 - 2.5e-06 27.9 0.1 5.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 KII85150.1 - 0.0002 21.2 0.2 0.00031 20.6 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KII85150.1 - 0.00031 20.7 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 KII85150.1 - 0.0011 19.4 0.0 0.0071 16.7 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KII85150.1 - 0.0089 16.3 0.8 0.32 11.3 0.6 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII85150.1 - 0.009 16.4 0.2 0.039 14.3 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KII85150.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KII85150.1 - 0.11 12.9 0.1 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA C-terminal domain Mg_chelatase PF01078.21 KII85150.1 - 0.11 11.8 0.0 0.42 10.0 0.0 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI HD PF01966.22 KII85151.1 - 0.00019 21.6 0.2 0.002 18.3 0.2 2.2 1 1 0 1 1 1 1 HD domain Pex26 PF07163.12 KII85152.1 - 0.00018 20.9 0.1 0.0004 19.8 0.0 1.6 2 0 0 2 2 2 1 Pex26 protein WD40 PF00400.32 KII85153.1 - 3.6e-16 59.3 4.3 0.0034 18.2 0.4 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KII85153.1 - 0.048 12.3 0.1 0.13 10.9 0.1 1.7 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Glyco_hydro_10 PF00331.20 KII85154.1 - 4.1e-101 338.3 0.0 4.7e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KII85154.1 - 1.9e-12 46.9 12.7 1.9e-12 46.9 12.7 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.20 KII85155.1 - 4e-102 341.6 0.0 4.6e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PEX11 PF05648.14 KII85156.1 - 5.2e-12 45.7 0.0 2.9e-10 40.0 0.0 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GST_N PF02798.20 KII85157.1 - 2e-18 66.5 0.0 3.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KII85157.1 - 1.6e-15 57.2 0.0 2.7e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII85157.1 - 5.1e-13 49.1 0.0 9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII85157.1 - 2.9e-11 43.4 0.0 4.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII85157.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KII85157.1 - 0.12 13.2 0.0 0.44 11.3 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Fungal_trans_2 PF11951.8 KII85158.1 - 1.2e-27 96.8 1.4 1.4e-27 96.5 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85158.1 - 1.5e-05 25.0 10.1 4.1e-05 23.6 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KII85159.1 - 4e-24 85.2 39.8 2.1e-23 82.9 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 KII85160.1 - 6.6e-87 292.3 0.0 2.4e-86 290.5 0.0 1.8 1 1 0 1 1 1 1 Amidase GMC_oxred_N PF00732.19 KII85161.1 - 7.9e-63 212.6 0.0 1e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII85161.1 - 2.4e-38 131.9 0.0 4.4e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII85161.1 - 0.001 18.2 0.1 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII85161.1 - 0.031 14.5 0.1 0.094 13.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII85161.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family PrgI PF12666.7 KII85162.1 - 4.5 8.0 9.0 0.43 11.3 3.9 2.0 2 1 0 2 2 2 0 PrgI family protein eIF3_subunit PF08597.10 KII85163.1 - 1.4e-64 218.4 20.8 1.5e-64 218.2 20.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CBP_BcsG PF11658.8 KII85163.1 - 0.13 10.6 1.2 0.12 10.7 0.1 1.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG COQ9 PF08511.11 KII85164.1 - 1e-11 44.4 0.1 1.8e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 COQ9 IP_trans PF02121.18 KII85165.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein DEAD PF00270.29 KII85166.1 - 2e-35 122.2 0.1 3.4e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII85166.1 - 1.3e-26 93.1 0.3 4.3e-26 91.4 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KII85166.1 - 0.02 15.2 1.8 0.44 10.8 0.9 2.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KII85166.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPP_enzyme_C PF02775.21 KII85166.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F-box-like PF12937.7 KII85167.1 - 2.2e-10 40.2 0.6 6.4e-10 38.8 0.6 1.9 1 0 0 1 1 1 1 F-box-like DUF1860 PF08949.10 KII85167.1 - 0.23 11.2 0.1 0.38 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Plavaka PF18759.1 KII85168.1 - 1.9e-120 402.0 0.0 6.3e-120 400.3 0.0 1.8 2 0 0 2 2 2 1 Plavaka transposase FAM199X PF15814.5 KII85169.1 - 0.4 9.7 3.0 0.82 8.7 3.0 1.4 1 0 0 1 1 1 0 Protein family FAM199X BTV_NS2 PF04514.12 KII85170.1 - 0.18 10.6 5.1 0.28 10.0 5.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop14 PF04147.12 KII85170.1 - 8.5 4.4 9.9 12 4.0 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 KII85170.1 - 9.2 6.3 11.5 3.5 7.6 9.0 1.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Plavaka PF18759.1 KII85171.1 - 1.7e-25 89.9 0.0 2.9e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase TEA PF01285.18 KII85172.1 - 9e-19 67.3 0.1 1.8e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 TEA/ATTS domain HLH PF00010.26 KII85173.1 - 7.8e-08 32.2 0.0 1.8e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain CHDCT2 PF08074.11 KII85173.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain THUMP PF02926.17 KII85174.1 - 1.5e-08 34.8 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.12 KII85174.1 - 0.096 12.4 1.3 0.14 11.9 1.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CBP PF12192.8 KII85174.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Fungal calcium binding protein F_actin_cap_B PF01115.17 KII85176.1 - 1.6e-107 358.6 0.0 1.9e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pro_isomerase PF00160.21 KII85177.1 - 7e-48 162.9 0.0 8.1e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.20 KII85178.1 - 4.2e-122 407.7 0.0 5e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII85178.1 - 2.6e-14 53.1 0.5 8.7e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 KII85178.1 - 3.8e-05 23.3 0.1 0.0076 15.9 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KII85178.1 - 0.00014 22.1 0.0 0.7 10.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KII85178.1 - 0.0018 17.7 0.6 0.91 8.8 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KII85178.1 - 0.0031 17.4 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 KII85178.1 - 0.0097 15.3 0.3 0.02 14.3 0.1 1.6 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 KII85178.1 - 0.017 14.9 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KII85178.1 - 0.043 13.5 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Methyltransf_23 PF13489.6 KII85179.1 - 3.9e-06 26.8 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KII85179.1 - 0.024 14.2 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 KII85179.1 - 0.077 13.7 0.0 2.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KII85179.1 - 0.09 13.5 0.0 0.33 11.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KII85179.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP_synt_H PF05493.13 KII85180.1 - 1.8e-19 69.9 6.1 2.2e-19 69.6 6.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.6 KII85180.1 - 0.054 13.1 2.4 0.062 13.0 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Saf_2TM PF18303.1 KII85180.1 - 0.054 13.1 0.2 0.06 12.9 0.2 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Phage_holin_3_6 PF07332.11 KII85180.1 - 0.1 12.7 1.9 0.12 12.4 1.9 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1145 PF06611.12 KII85180.1 - 0.1 12.6 4.5 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1145) p450 PF00067.22 KII85181.1 - 8.6e-74 248.9 0.0 1e-73 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.19 KII85182.1 - 4.9e-50 170.7 0.0 1.2e-49 169.5 0.0 1.7 1 1 0 1 1 1 1 RNB domain TFIIF_alpha PF05793.12 KII85183.1 - 0.025 13.2 21.3 0.028 13.0 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KII85183.1 - 0.07 12.6 20.2 0.088 12.2 20.2 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KII85183.1 - 1.7 7.9 27.8 2.1 7.6 27.8 1.0 1 0 0 1 1 1 0 BUD22 FRG2 PF15315.6 KII85183.1 - 2.4 8.3 10.7 4.2 7.5 10.7 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Presenilin PF01080.17 KII85183.1 - 7.6 5.2 5.7 8.4 5.0 5.7 1.1 1 0 0 1 1 1 0 Presenilin P_proprotein PF01483.20 KII85184.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Proprotein convertase P-domain Asp PF00026.23 KII85185.1 - 6.3e-53 180.2 15.6 1.4e-52 179.1 15.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85185.1 - 2.2e-06 28.0 7.0 0.0016 18.7 0.2 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII85185.1 - 0.011 16.4 4.6 0.54 10.9 1.7 2.8 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KII85185.1 - 0.049 13.4 0.3 5.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF4688 PF15752.5 KII85187.1 - 0.018 14.3 0.1 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4688) ATE_N PF04376.13 KII85187.1 - 0.041 14.3 0.3 0.068 13.6 0.3 1.7 1 1 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Adeno_E4 PF05385.11 KII85188.1 - 0.11 12.6 0.4 6.6 6.9 0.1 2.3 1 1 1 2 2 2 0 Mastadenovirus early E4 13 kDa protein GSHPx PF00255.19 KII85189.1 - 2.8e-40 136.3 0.1 3.5e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KII85189.1 - 1.4e-05 25.0 0.0 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII85189.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.5 1 1 0 1 1 1 1 Redoxin Sacchrp_dh_NADP PF03435.18 KII85190.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FHA PF00498.26 KII85190.1 - 0.16 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 FHA domain F-box-like PF12937.7 KII85191.1 - 5.8e-08 32.5 0.4 5.8e-08 32.5 0.4 2.6 3 0 0 3 3 3 1 F-box-like Vps51 PF08700.11 KII85192.1 - 3.3e-25 88.0 0.4 4.8e-25 87.5 0.4 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 KII85192.1 - 0.0013 18.9 0.8 0.002 18.3 0.8 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 KII85192.1 - 0.0051 15.5 1.5 0.0064 15.2 1.5 1.1 1 0 0 1 1 1 1 Dor1-like family Spc7 PF08317.11 KII85192.1 - 0.064 12.1 1.1 0.081 11.8 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Surfac_D-trimer PF09006.11 KII85192.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Remorin_N PF03766.13 KII85193.1 - 0.13 12.4 0.4 0.28 11.3 0.4 1.6 1 0 0 1 1 1 0 Remorin, N-terminal region NTP_transf_9 PF04248.12 KII85194.1 - 1.1e-37 127.8 0.1 1.4e-29 101.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF1080 PF06439.11 KII85194.1 - 0.03 14.4 0.0 11 6.1 0.0 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1080) GTP_EFTU PF00009.27 KII85195.1 - 9.6e-69 230.8 0.1 1.4e-68 230.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KII85195.1 - 7.2e-34 116.2 0.0 1.9e-33 114.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KII85195.1 - 1e-21 76.8 0.0 2.1e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KII85195.1 - 8.3e-13 48.2 0.0 2.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KII85195.1 - 2e-07 31.3 0.0 6.9e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII85195.1 - 0.00027 21.0 0.2 0.0006 19.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII85195.1 - 0.072 13.0 0.1 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase BTB PF00651.31 KII85196.1 - 0.00061 20.0 0.2 0.0011 19.1 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain LemA PF04011.12 KII85198.1 - 0.0018 18.1 7.1 0.0025 17.7 7.1 1.2 1 0 0 1 1 1 1 LemA family DUF3818 PF12825.7 KII85198.1 - 0.025 13.6 2.2 0.028 13.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Ig_GlcNase PF18368.1 KII85198.1 - 0.42 10.8 3.3 0.23 11.7 1.2 1.6 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain p450 PF00067.22 KII85199.1 - 9.5e-72 242.2 0.0 1.2e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 KII85202.1 - 0.00023 21.4 0.1 0.0045 17.2 0.0 2.8 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.31 KII85204.1 - 3.7e-06 27.1 0.1 0.0023 18.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain F-box-like PF12937.7 KII85207.1 - 0.00066 19.5 0.1 0.0019 18.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 KII85209.1 - 1.3e-06 29.0 0.0 2.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KII85209.1 - 0.011 14.1 0.7 0.046 12.0 0.0 1.9 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Mersacidin PF16934.5 KII85209.1 - 0.04 13.7 1.2 6.7 6.6 0.2 2.4 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) eIF-5_eIF-2B PF01873.17 KII85210.1 - 1.9e-38 130.9 0.0 3.5e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KII85210.1 - 7.2e-22 77.3 0.2 4.8e-21 74.7 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Whi5 PF08528.11 KII85211.1 - 2.4e-07 30.2 2.0 5.7e-07 29.0 2.0 1.7 1 0 0 1 1 1 1 Whi5 like Pkinase PF00069.25 KII85212.1 - 1.4e-42 145.9 0.0 1.6e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII85212.1 - 5e-20 71.9 0.0 3.6e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KII85212.1 - 2.5e-07 30.3 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Ribosomal_60s PF00428.19 KII85212.1 - 0.00073 20.1 0.7 0.00073 20.1 0.7 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein APH PF01636.23 KII85212.1 - 0.0043 17.0 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family C1ORF64 PF15547.6 KII85212.1 - 0.19 12.2 0.7 0.45 11.0 0.7 1.6 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein BTB PF00651.31 KII85216.1 - 0.03 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Abhydrolase_1 PF00561.20 KII85217.1 - 2.2e-22 80.0 0.0 4.4e-21 75.7 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KII85217.1 - 1.4e-18 66.9 0.1 4.2e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 KII85217.1 - 0.022 14.0 0.0 8.7 5.5 0.0 3.1 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KII85218.1 - 3.4e-22 78.5 0.1 1e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KII85218.1 - 5.9e-20 72.0 0.1 2.6e-18 66.6 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII85218.1 - 0.027 13.7 0.0 4.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII85218.1 - 0.21 11.0 0.1 7 6.1 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family p450 PF00067.22 KII85219.1 - 6e-65 219.8 0.0 7.7e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_2 PF07719.17 KII85220.1 - 3.6e-11 42.3 8.2 0.00039 20.3 1.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII85220.1 - 1e-07 32.3 2.6 1e-07 32.3 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII85220.1 - 2.3e-07 31.1 0.3 0.019 15.8 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII85220.1 - 3.7e-06 27.5 3.6 0.0013 19.4 0.6 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII85220.1 - 2.4e-05 24.2 7.0 0.014 15.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII85220.1 - 0.0001 22.0 9.0 0.013 15.3 1.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII85220.1 - 0.00011 22.6 2.2 0.32 11.7 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KII85220.1 - 0.00026 21.2 0.9 0.00092 19.4 0.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KII85220.1 - 0.0061 16.5 0.6 2.5 8.3 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 KII85220.1 - 0.012 15.9 0.3 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 PPR repeat TPR_17 PF13431.6 KII85220.1 - 0.021 15.1 4.7 5.4 7.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII85220.1 - 0.023 15.0 3.7 0.049 13.9 1.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII85220.1 - 0.038 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FAT PF02259.23 KII85220.1 - 0.042 13.1 1.2 0.051 12.8 1.2 1.3 1 0 0 1 1 1 0 FAT domain Alkyl_sulf_dimr PF14863.6 KII85220.1 - 0.057 13.9 3.1 0.072 13.5 0.9 2.1 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 KII85220.1 - 0.066 13.3 4.4 0.3 11.2 0.8 2.7 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 KII85220.1 - 0.1 12.4 5.4 0.094 12.5 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) DUF2148 PF09918.9 KII85220.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) VWA_2 PF13519.6 KII85220.1 - 0.18 12.5 1.0 1.7 9.3 0.6 2.2 1 1 1 2 2 2 0 von Willebrand factor type A domain MIT PF04212.18 KII85220.1 - 0.23 11.6 5.5 1.2 9.3 1.0 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 KII85220.1 - 0.99 9.1 9.1 1.8 8.2 2.3 2.6 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_11 PF13414.6 KII85220.1 - 3.8 7.3 8.1 1.3 8.8 1.7 2.8 2 1 1 3 3 3 0 TPR repeat PAPA-1 PF04795.12 KII85221.1 - 0.16 12.8 2.7 0.23 12.3 2.7 1.2 1 0 0 1 1 1 0 PAPA-1-like conserved region Pkinase_fungal PF17667.1 KII85222.1 - 1.2e-47 162.7 0.0 2.9e-46 158.1 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII85222.1 - 0.0032 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII85222.1 - 0.016 15.2 0.2 0.13 12.1 0.2 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KII85222.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DFRP_C PF16543.5 KII85224.1 - 1.5e-31 108.7 3.9 1.5e-31 108.7 3.9 3.7 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KII85224.1 - 2.6e-08 33.6 7.0 1.5e-05 24.8 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KII85224.1 - 2.2e-06 28.4 19.3 1.3e-05 25.8 3.3 3.6 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 KII85224.1 - 2.7e-06 27.0 13.1 0.0069 16.2 3.3 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KII85224.1 - 2.9e-06 27.1 19.9 0.00087 19.3 7.9 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KII85224.1 - 0.0017 18.6 4.7 0.28 11.4 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KII85224.1 - 0.042 14.3 13.8 1.3 9.6 5.6 2.5 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger BTB PF00651.31 KII85225.1 - 0.032 14.5 0.0 4 7.7 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain SET PF00856.28 KII85226.1 - 7.9e-10 39.4 0.0 4e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 KII85226.1 - 0.00014 22.4 6.5 0.0042 17.7 0.2 3.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII85226.1 - 0.0034 17.4 5.1 0.43 10.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII85226.1 - 0.0037 17.7 0.3 0.39 11.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII85226.1 - 0.02 14.7 0.1 0.7 9.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII85226.1 - 0.063 14.1 4.2 0.73 10.8 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII85226.1 - 0.48 10.6 3.0 1.9 8.7 1.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 KII85227.1 - 0.26 11.5 0.3 1.8 8.8 0.1 2.4 2 1 1 3 3 3 0 PPR repeat family Ribosomal_L10 PF00466.20 KII85228.1 - 5.2e-25 87.5 1.3 1.2e-24 86.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KII85228.1 - 3.4e-22 78.8 11.3 4.8e-22 78.3 7.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 KII85228.1 - 2.4e-21 75.5 0.1 4.5e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Glyco_transf_20 PF00982.21 KII85229.1 - 8.9e-185 614.9 0.0 2.1e-184 613.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KII85229.1 - 0.0025 18.2 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PsbR PF04725.12 KII85229.1 - 0.16 12.4 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR S10_plectin PF03501.15 KII85230.1 - 2.6e-44 149.2 0.2 3.1e-44 149.0 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KII85230.1 - 0.0038 17.1 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 KII85230.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation Nop14 PF04147.12 KII85231.1 - 0.21 9.8 20.7 0.31 9.2 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KII85231.1 - 1.6 7.2 11.9 2.3 6.6 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.32 KII85233.1 - 2.7e-05 24.8 14.1 2.2 9.3 0.1 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII85233.1 - 0.00018 21.8 0.1 0.088 13.1 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KII85233.1 - 0.016 15.7 0.0 3.5 8.2 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Pkinase_fungal PF17667.1 KII85235.1 - 9.6e-43 146.5 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KII85235.1 - 0.0037 16.9 0.1 0.0067 16.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KII85235.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KII85235.1 - 0.11 12.4 0.1 0.4 10.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C3HC PF07967.13 KII85236.1 - 3.3e-25 88.7 0.0 1.5e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 KII85236.1 - 4.5e-13 49.2 0.2 1.8e-08 34.4 0.0 3.4 3 0 0 3 3 3 2 Rsm1-like DM PF00751.18 KII85236.1 - 3.2 7.7 6.9 7.1 6.6 0.1 2.6 3 0 0 3 3 3 0 DM DNA binding domain Pkinase_fungal PF17667.1 KII85237.1 - 5.1e-15 55.1 0.1 8e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF2370 PF10176.9 KII85239.1 - 2.3e-65 220.4 0.0 3.8e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) O-FucT PF10250.9 KII85240.1 - 8.8e-09 35.5 0.0 3.9e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-MYND PF01753.18 KII85242.1 - 1e-10 41.5 10.7 2.4e-10 40.3 10.7 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII85242.1 - 0.34 11.3 10.3 0.69 10.3 10.3 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf_C2H2_13 PF18508.1 KII85242.1 - 0.66 9.6 3.7 17 5.1 1.1 2.5 1 1 1 2 2 2 0 Zinc finger domain BAH PF01426.18 KII85243.1 - 3.5e-15 55.9 0.0 1e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 BAH domain AAA PF00004.29 KII85243.1 - 2.1e-14 54.1 0.0 3.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII85243.1 - 1.8e-09 38.2 0.0 7.3e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 KII85243.1 - 1.8e-07 31.2 0.1 4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KII85243.1 - 2.3e-06 27.9 0.0 5.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KII85243.1 - 0.00065 19.0 0.0 0.002 17.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KII85243.1 - 0.00085 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KII85243.1 - 0.0094 15.9 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KII85243.1 - 0.046 13.5 1.6 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KII85243.1 - 0.06 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KII85243.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KII85243.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PIF1 PF05970.14 KII85243.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Aldose_epim PF01263.20 KII85244.1 - 4.7e-26 91.8 0.0 1.2e-11 44.5 0.0 3.2 1 1 1 2 2 2 2 Aldose 1-epimerase Fungal_trans PF04082.18 KII85245.1 - 1.1e-29 103.3 0.0 2.2e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85245.1 - 0.00026 21.1 5.0 0.00049 20.2 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_C PF00034.21 KII85246.1 - 2.5e-09 38.2 0.1 3.8e-09 37.6 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KII85246.1 - 2.9e-07 30.7 3.0 3.3e-06 27.3 3.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KII85246.1 - 0.00015 21.5 0.9 0.00086 19.0 0.2 2.1 1 1 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KII85246.1 - 0.047 14.3 0.0 0.051 14.2 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase GFO_IDH_MocA PF01408.22 KII85247.1 - 2.6e-16 60.5 0.0 6.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII85247.1 - 0.00066 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KII85247.1 - 0.027 15.1 0.0 0.063 13.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DSPc PF00782.20 KII85249.1 - 8.3e-23 80.7 0.0 9.6e-20 70.8 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII85249.1 - 0.059 12.9 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ABC2_membrane PF01061.24 KII85250.1 - 2.9e-34 118.3 20.4 2.9e-34 118.3 20.4 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 KII85250.1 - 7.2e-28 97.8 0.0 1.1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII85250.1 - 4.3e-06 26.8 0.0 0.039 13.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII85250.1 - 0.0012 18.5 0.3 0.0025 17.5 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 KII85250.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain EGF_2 PF07974.13 KII85250.1 - 0.0029 17.9 33.4 0.0042 17.4 12.9 3.9 3 0 0 3 3 3 2 EGF-like domain Rad17 PF03215.15 KII85250.1 - 0.0053 16.7 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 KII85250.1 - 0.0063 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KII85250.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KII85250.1 - 0.078 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KII85250.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KII85250.1 - 0.11 12.9 0.4 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KII85250.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 KII85250.1 - 0.26 10.3 29.6 0.041 13.0 23.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein GalKase_gal_bdg PF10509.9 KII85252.1 - 2e-20 72.1 0.1 4.1e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KII85252.1 - 6.2e-13 48.8 2.0 1.7e-12 47.3 2.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KII85252.1 - 2.3e-11 43.9 0.4 6.2e-11 42.5 0.1 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal NmrA PF05368.13 KII85253.1 - 2.2e-50 171.4 0.0 2.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII85253.1 - 4.7e-17 62.5 0.0 8.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII85253.1 - 0.00023 20.7 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII85253.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KII85253.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Nitro_FeMo-Co PF02579.17 KII85253.1 - 0.044 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor zf-C2H2 PF00096.26 KII85256.1 - 0.0049 17.3 2.7 0.0076 16.7 0.9 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85256.1 - 0.038 14.8 0.6 0.038 14.8 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KII85256.1 - 0.18 12.0 0.2 0.18 12.0 0.2 1.5 2 0 0 2 2 2 0 Aberrant zinc-finger HSP20 PF00011.21 KII85257.1 - 1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Dickkopf_N PF04706.12 KII85258.1 - 0.00089 19.7 29.8 0.013 15.9 8.8 4.1 4 0 0 4 4 4 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KII85258.1 - 0.0025 18.1 26.0 0.096 13.0 10.3 4.6 1 1 3 4 4 4 2 EB module Aminotran_MocR PF12897.7 KII85258.1 - 0.042 12.6 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Ycf34 PF10718.9 KII85258.1 - 0.066 13.9 0.1 0.066 13.9 0.1 1.9 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 PPI_Ypi1 PF07491.11 KII85259.1 - 2.2e-25 88.2 0.7 5.7e-25 86.9 0.7 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.12 KII85259.1 - 0.22 10.1 7.5 0.23 10.0 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) STIL_N PF15253.6 KII85259.1 - 0.4 9.6 1.9 0.58 9.1 1.9 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus DUF1752 PF08550.10 KII85260.1 - 3.8e-11 42.6 2.8 7.7e-11 41.6 2.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 KII85260.1 - 2.1e-06 27.4 50.1 0.00026 20.5 42.2 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) BNIP2 PF12496.8 KII85260.1 - 3.1 8.2 9.0 0.14 12.6 2.4 2.2 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 IDO PF01231.18 KII85262.1 - 1.4e-135 452.5 0.0 1.6e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Herpes_pp85 PF04637.12 KII85262.1 - 0.41 9.0 2.0 0.63 8.4 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Epimerase PF01370.21 KII85263.1 - 0.03 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TFIIF_beta PF02270.15 KII85264.1 - 7.7e-26 90.0 0.1 1.2e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KII85264.1 - 3e-21 76.5 0.0 5.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus DDE_Tnp_IS66_C PF13817.6 KII85264.1 - 0.15 12.3 0.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 IS66 C-terminal element HAD_2 PF13419.6 KII85267.1 - 9e-11 42.2 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII85267.1 - 9e-08 32.7 0.0 1.9e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KII85267.1 - 1.1e-06 28.6 0.0 1.4e-05 25.1 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KII85267.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.7 KII85267.1 - 0.051 14.0 0.1 0.1 13.0 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DHHC PF01529.20 KII85268.1 - 4.4e-30 104.5 6.5 4.4e-30 104.5 6.5 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase MIS13 PF08202.11 KII85269.1 - 5.7e-28 98.1 0.9 5.7e-28 98.1 0.9 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family CLZ PF16526.5 KII85269.1 - 0.029 14.7 3.8 0.92 9.9 0.2 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RIO1 PF01163.22 KII85271.1 - 3.1e-05 23.7 0.2 8.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KII85271.1 - 0.00028 20.9 0.0 0.00038 20.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KII85271.1 - 0.0012 18.2 0.1 0.0053 16.2 0.0 2.1 1 1 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KII85271.1 - 0.0016 18.1 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KII85271.1 - 0.038 12.8 0.1 0.39 9.4 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KII85271.1 - 0.058 12.7 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII85272.1 - 4.9e-05 23.4 0.5 0.00012 22.0 0.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII85272.1 - 0.00082 19.0 1.7 0.0015 18.2 0.1 2.1 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.14 KII85272.1 - 0.0029 17.0 0.2 0.0049 16.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII85272.1 - 0.028 13.8 0.2 0.066 12.6 0.0 1.7 2 1 0 2 2 2 0 Protein kinase domain DUF4135 PF13575.6 KII85272.1 - 0.2 11.0 0.8 0.44 9.8 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4135) LRRFIP PF09738.9 KII85273.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 LRRFIP family DPBB_1 PF03330.18 KII85274.1 - 0.012 15.9 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 0 Lytic transglycolase DNA_pol_phi PF04931.13 KII85276.1 - 0.08 11.0 1.5 0.08 11.0 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi FlxA PF14282.6 KII85277.1 - 0.79 9.7 7.8 0.87 9.6 0.5 2.4 2 0 0 2 2 2 0 FlxA-like protein FUSC PF04632.12 KII85277.1 - 1.9 6.9 4.7 3.2 6.2 4.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIP-T3_C PF17749.1 KII85277.1 - 2.3 8.2 9.3 0.29 11.1 4.4 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4407 PF14362.6 KII85277.1 - 2.5 7.4 12.1 3.1 7.1 11.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mu-like_Pro PF10123.9 KII85277.1 - 4.9 6.6 12.4 0.87 9.1 1.1 2.1 1 1 1 2 2 2 0 Mu-like prophage I protein TMF_DNA_bd PF12329.8 KII85277.1 - 7.1 6.7 22.3 0.084 12.9 10.7 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 KII85278.1 - 0.048 13.7 26.1 0.38 10.8 14.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FIVAR PF07554.13 KII85278.1 - 0.13 13.0 7.2 0.38 11.6 7.2 1.9 1 0 0 1 1 1 0 FIVAR domain NYD-SP28_assoc PF14775.6 KII85278.1 - 0.23 11.6 6.0 0.46 10.6 0.1 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain HAD_SAK_2 PF18143.1 KII85278.1 - 0.24 11.7 2.1 0.27 11.5 1.0 1.8 1 1 1 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins ExsD PF16806.5 KII85278.1 - 0.28 11.1 6.5 0.27 11.1 0.4 2.2 1 1 1 2 2 2 0 Antiactivator protein ExsD DUF3584 PF12128.8 KII85278.1 - 0.63 7.5 20.7 0.73 7.3 20.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 KII85278.1 - 0.76 9.5 18.6 2.4 7.9 16.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) SNARE PF05739.19 KII85278.1 - 0.78 9.8 2.6 0.65 10.0 0.2 2.1 2 0 0 2 2 2 0 SNARE domain CcdA PF07362.12 KII85278.1 - 2 8.9 11.4 0.4 11.1 4.4 2.8 2 2 1 3 3 3 0 Post-segregation antitoxin CcdA THOC7 PF05615.13 KII85278.1 - 3.7 7.8 22.8 2.6 8.4 3.3 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 LMBR1 PF04791.16 KII85278.1 - 3.9 6.3 7.9 4.9 5.9 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.9 KII85278.1 - 6.6 7.5 14.8 11 6.8 1.9 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.8 KII85278.1 - 8.2 5.7 22.0 0.72 9.1 2.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) GST_N_3 PF13417.6 KII85279.1 - 7.3e-18 64.8 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII85279.1 - 2.9e-17 62.8 0.0 5.1e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII85279.1 - 1.8e-15 56.9 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KII85279.1 - 2.4e-09 37.3 0.0 4.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII85279.1 - 4.6e-07 29.8 0.2 2.9e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII85279.1 - 2.9e-06 27.4 0.0 4.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 KII85280.1 - 2e-06 27.6 0.1 3e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII85280.1 - 2.7e-06 27.4 0.9 3.7e-06 27.0 0.9 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII85280.1 - 3.8e-05 23.3 0.0 0.052 13.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII85280.1 - 0.002 17.3 0.2 0.0034 16.6 0.2 1.3 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KII85280.1 - 0.074 13.5 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII85280.1 - 0.075 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KII85280.1 - 0.21 10.7 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lon_C PF05362.13 KII85281.1 - 7.7e-68 228.1 0.2 1.4e-67 227.2 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KII85281.1 - 2.2e-36 125.7 0.1 6.8e-36 124.1 0.1 1.9 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KII85281.1 - 2.9e-22 79.5 0.0 9.5e-22 77.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KII85281.1 - 2.1e-08 34.2 0.0 4.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KII85281.1 - 6.6e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 KII85281.1 - 1.8e-05 23.8 0.0 3.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.14 KII85281.1 - 2.4e-05 24.5 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KII85281.1 - 0.00018 22.0 0.0 0.00059 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KII85281.1 - 0.00019 21.2 0.0 0.00085 19.1 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KII85281.1 - 0.00025 21.3 0.0 0.0032 17.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain SPX PF03105.19 KII85281.1 - 0.00075 19.5 0.7 0.38 10.6 0.0 2.4 2 0 0 2 2 2 2 SPX domain AAA_18 PF13238.6 KII85281.1 - 0.0013 19.2 0.5 0.0036 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KII85281.1 - 0.0047 17.0 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KII85281.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KII85281.1 - 0.034 14.5 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KII85281.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 KII85281.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.13 KII85281.1 - 0.058 12.6 0.7 0.21 10.8 0.1 2.1 3 0 0 3 3 2 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 KII85281.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 KII85281.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 KII85281.1 - 0.084 12.8 0.2 0.52 10.2 0.1 2.3 2 1 1 3 3 2 0 NTPase ATPase_2 PF01637.18 KII85281.1 - 0.086 12.7 1.3 10 5.9 0.0 3.1 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KII85281.1 - 0.096 12.4 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 KII85281.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KII85281.1 - 0.13 12.8 0.1 0.38 11.3 0.1 1.7 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KII85281.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KII85281.1 - 0.17 11.4 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PrpF PF04303.13 KII85286.1 - 4.6e-78 262.8 0.2 5.7e-78 262.5 0.2 1.0 1 0 0 1 1 1 1 PrpF protein XRN1_D1 PF18332.1 KII85287.1 - 8.2e-51 172.5 0.0 2.4e-50 171.0 0.0 1.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KII85287.1 - 3.5e-32 110.5 0.3 6.2e-32 109.7 0.3 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KII85288.1 - 2.5e-23 82.0 0.3 3.6e-23 81.4 0.3 1.3 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KII85288.1 - 1.9e-10 40.7 0.4 2.8e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 GFA PF04828.14 KII85289.1 - 5e-26 90.9 0.1 5e-26 90.9 0.1 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CDC27 PF09507.10 KII85292.1 - 5.5e-49 167.7 45.7 9.6e-49 166.9 45.7 1.4 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PS_Dcarbxylase PF02666.15 KII85293.1 - 2.5e-58 197.0 0.0 3.7e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KII85293.1 - 6e-37 126.1 0.0 3.4e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 KII85293.1 - 0.1 12.5 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain HTHP PF11534.8 KII85293.1 - 0.12 12.8 0.0 13 6.3 0.0 2.9 3 0 0 3 3 3 0 Hexameric tyrosine-coordinated heme protein (HTHP) GMP_synt_C PF00958.22 KII85294.1 - 8.9e-45 150.7 0.1 1.7e-44 149.8 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KII85294.1 - 1.8e-29 102.9 0.0 3.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KII85294.1 - 7.2e-10 38.4 0.3 3.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KII85294.1 - 1.3e-09 38.1 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KII85294.1 - 0.003 16.4 0.1 0.0051 15.6 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 KII85294.1 - 0.0072 15.9 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 KII85294.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 KII85294.1 - 0.071 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 KII85294.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family UPF0242 PF06785.11 KII85295.1 - 2.1e-05 24.7 3.0 3.5e-05 24.0 3.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF737 PF05300.11 KII85295.1 - 0.043 14.2 10.7 0.043 14.2 9.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF3037 PF11236.8 KII85295.1 - 0.045 14.2 4.4 0.095 13.1 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) MPS2 PF17060.5 KII85295.1 - 0.072 12.4 1.4 0.12 11.6 1.4 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Atg14 PF10186.9 KII85295.1 - 0.17 10.9 9.1 0.3 10.1 9.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SpecificRecomb PF10136.9 KII85295.1 - 0.22 9.8 7.6 0.29 9.4 7.6 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF4349 PF14257.6 KII85295.1 - 0.22 10.9 6.7 0.39 10.1 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF1043 PF06295.12 KII85295.1 - 0.25 11.4 4.2 0.49 10.4 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) SlyX PF04102.12 KII85295.1 - 0.8 10.4 7.5 2.8 8.6 7.5 1.9 1 0 0 1 1 1 0 SlyX Exonuc_VII_L PF02601.15 KII85295.1 - 0.83 9.2 7.1 1.2 8.7 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Caskin1-CID PF16600.5 KII85295.1 - 1.5 9.5 4.8 2.8 8.6 4.8 1.4 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain Adaptin_binding PF10199.9 KII85295.1 - 2.3 8.8 7.3 4.3 8.0 7.3 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 FapA PF03961.13 KII85295.1 - 2.8 6.4 4.5 4.2 5.9 4.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cut12 PF11500.8 KII85295.1 - 3.7 7.5 7.4 2.6 8.0 5.4 1.7 1 1 0 1 1 1 0 Spindle pole body formation-associated protein RhaT PF06379.12 KII85297.1 - 0.0012 18.2 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 L-rhamnose-proton symport protein (RhaT) Tad PF13400.6 KII85298.1 - 0.05 13.9 0.3 0.05 13.9 0.3 1.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like RhaT PF06379.12 KII85301.1 - 0.0011 18.3 0.9 0.0012 18.2 0.3 1.4 1 1 0 1 1 1 1 L-rhamnose-proton symport protein (RhaT) AtpR PF12966.7 KII85301.1 - 4.5 7.8 8.4 7.3 7.1 5.7 2.6 1 1 1 2 2 2 0 N-ATPase, AtpR subunit MFS_1 PF07690.16 KII85303.1 - 6.4e-17 61.5 38.5 8.1e-17 61.2 36.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 KII85304.1 - 1.8e-07 30.9 1.4 2.8e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII85304.1 - 0.069 13.1 0.1 0.27 11.2 0.2 2.0 2 0 0 2 2 2 0 F-box domain SF1-HH PF16275.5 KII85306.1 - 0.094 13.1 0.1 0.14 12.5 0.1 1.3 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain SecD_SecF PF02355.16 KII85308.1 - 0.068 12.6 6.0 0.11 11.9 6.0 1.3 1 0 0 1 1 1 0 Protein export membrane protein HisKA_4TM PF16926.5 KII85308.1 - 1.6 8.3 12.3 3.3 7.2 0.8 3.3 1 1 1 3 3 3 0 Archaeal 4TM region of histidine kinase Rota_NS26 PF01525.16 KII85311.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Rotavirus NS26 DUF4115 PF13464.6 KII85311.1 - 0.87 9.8 4.0 2.1 8.6 0.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4115) GATA PF00320.27 KII85313.1 - 0.32 10.6 5.4 2.3 7.9 0.5 2.4 2 0 0 2 2 2 0 GATA zinc finger YABBY PF04690.13 KII85316.1 - 4.1e-08 33.9 3.7 4.1e-08 33.9 3.7 1.6 1 1 1 2 2 2 1 YABBY protein HMG_box PF00505.19 KII85316.1 - 4.9e-07 30.1 0.7 4.9e-07 30.1 0.7 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII85316.1 - 0.00012 22.6 0.4 0.00012 22.6 0.4 2.3 2 1 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 KII85316.1 - 0.00041 20.9 2.4 0.00041 20.9 2.4 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF4449 PF14613.6 KII85317.1 - 1.2e-11 45.1 0.7 2e-10 41.0 0.0 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) CENP-B_dimeris PF09026.10 KII85318.1 - 0.02 15.3 1.2 0.038 14.4 1.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3357 PF11837.8 KII85318.1 - 0.052 14.0 0.0 0.18 12.3 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.6 KII85318.1 - 1.8 9.0 6.9 0.24 11.8 0.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dimer_Tnp_hAT PF05699.14 KII85324.1 - 4.9e-06 26.3 0.1 9.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region S4 PF01479.25 KII85325.1 - 2.7e-09 36.6 0.0 4.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KII85325.1 - 0.0007 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 S4 domain SPT_ssu-like PF11779.8 KII85326.1 - 1.2e-17 63.3 5.9 1.7e-17 62.8 5.9 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ferric_reduct PF01794.19 KII85327.1 - 3e-18 66.1 9.7 6.8e-18 65.0 9.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KII85327.1 - 3.6e-14 52.8 0.0 9.4e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KII85327.1 - 2.2e-08 34.4 0.0 1.9e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain CUE PF02845.16 KII85328.1 - 5.7e-12 45.1 0.0 8.4e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KII85328.1 - 0.012 15.3 3.6 0.02 14.5 3.6 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) MRP-S25 PF13741.6 KII85328.1 - 0.021 14.4 0.5 0.033 13.7 0.5 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S25 SNARE PF05739.19 KII85330.1 - 6.3e-08 32.5 0.2 6.3e-08 32.5 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Fusion_gly PF00523.18 KII85330.1 - 0.046 12.0 0.2 0.065 11.5 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF2576 PF10845.8 KII85330.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) EzrA PF06160.12 KII85330.1 - 0.097 10.8 0.4 1 7.4 0.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Flp1_like PF16982.5 KII85330.1 - 0.45 10.0 4.5 0.76 9.2 4.5 1.3 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain EPSP_synthase PF00275.20 KII85332.1 - 3.4e-116 388.4 0.0 5.4e-116 387.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KII85332.1 - 9.5e-100 333.1 0.1 2.4e-99 331.8 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KII85332.1 - 7.4e-54 183.4 0.0 1.2e-53 182.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KII85332.1 - 8.3e-32 110.5 0.0 1.4e-30 106.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KII85332.1 - 9e-25 86.7 0.0 2.3e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KII85332.1 - 2.1e-07 30.9 0.1 5.2e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KII85332.1 - 3.9e-07 29.7 0.6 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KII85332.1 - 2.1e-06 27.9 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KII85332.1 - 0.0045 17.3 0.0 1.1 9.6 0.0 3.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 KII85332.1 - 0.051 14.0 0.1 0.54 10.6 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Pyr_redox_2 PF07992.14 KII85333.1 - 2.5e-55 187.8 0.1 3.2e-55 187.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII85333.1 - 1.2e-11 44.9 0.1 5.5e-10 39.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KII85333.1 - 0.00095 19.6 0.0 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KII85333.1 - 0.002 17.5 0.1 0.66 9.2 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase BPS1 PF05633.11 KII85333.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related MTS PF05175.14 KII85333.1 - 0.13 11.8 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Rib_5-P_isom_A PF06026.14 KII85335.1 - 1.3e-60 204.0 0.0 1.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Hydrolase_4 PF12146.8 KII85336.1 - 8.8e-13 48.1 0.0 7.6e-10 38.5 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII85336.1 - 9.8e-12 45.0 0.1 2.4e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KII85336.1 - 4.4e-06 26.8 0.0 7.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KII85336.1 - 6.9e-06 26.8 0.1 1e-05 26.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KII85336.1 - 9.1e-06 25.6 0.0 0.073 12.9 0.0 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 KII85336.1 - 0.00045 19.0 0.2 0.023 13.4 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KII85336.1 - 0.0025 17.3 0.0 0.013 15.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KII85336.1 - 0.0026 17.4 0.0 0.041 13.4 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KII85336.1 - 0.0095 15.8 0.2 0.088 12.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.12 KII85336.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 KII85336.1 - 0.021 14.5 0.0 0.49 10.1 0.0 2.2 1 1 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 KII85336.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1057 PF06342.12 KII85336.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S15 PF02129.18 KII85336.1 - 0.12 12.0 0.0 0.97 9.0 0.0 2.1 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KII85336.1 - 0.15 12.2 0.0 2.3 8.4 0.0 2.7 2 1 1 3 3 3 0 TAP-like protein Nab6_mRNP_bdg PF10567.9 KII85337.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 RNA-recognition motif GCP_N_terminal PF17681.1 KII85338.1 - 4.2e-62 210.5 0.0 8e-62 209.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KII85338.1 - 4.6e-58 197.1 5.2 4.6e-58 197.1 5.2 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Snapin_Pallidin PF14712.6 KII85338.1 - 0.11 12.9 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Tfb5 PF06331.12 KII85344.1 - 4.9e-24 84.1 0.7 5.4e-24 84.0 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Herpes_U44 PF04533.13 KII85344.1 - 0.068 12.8 0.2 0.072 12.7 0.2 1.0 1 0 0 1 1 1 0 Herpes virus U44 protein CBM_20 PF00686.19 KII85346.1 - 2.7e-53 177.8 5.8 3.9e-27 94.0 0.2 2.8 2 0 0 2 2 2 2 Starch binding domain Alpha-amylase_C PF02806.18 KII85346.1 - 2.4e-10 40.8 0.2 6.3e-09 36.2 0.1 3.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KII85346.1 - 2.6e-10 40.4 0.0 3.7e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain F-box-like PF12937.7 KII85351.1 - 4.4e-08 32.9 1.3 8e-08 32.1 1.3 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KII85352.1 - 1.5e-83 272.5 52.5 1.6e-10 41.4 0.6 10.0 9 2 1 10 10 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII85352.1 - 4.9e-29 100.5 2.0 0.032 14.5 0.0 8.5 1 1 8 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KII85352.1 - 2.2e-23 81.6 8.3 1 9.4 0.0 10.4 10 0 0 10 10 10 9 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KII85352.1 - 4.4e-19 68.6 17.3 0.051 12.5 0.1 8.9 1 1 8 9 9 9 8 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KII85352.1 - 1.9e-16 60.2 1.9 0.0003 20.2 0.0 5.2 3 2 1 5 5 5 5 WD40-like domain Frtz PF11768.8 KII85352.1 - 1.3e-11 43.6 0.0 0.016 13.6 0.0 4.9 2 1 1 5 5 5 5 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 KII85352.1 - 1.6e-06 27.1 9.0 0.87 8.2 0.1 5.6 2 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF1652 PF07865.11 KII85352.1 - 7.5e-05 22.5 0.0 21 5.0 0.0 6.3 2 1 5 7 7 7 0 Protein of unknown function (DUF1652) Cytochrom_D1 PF02239.16 KII85352.1 - 0.00052 18.6 6.2 0.18 10.3 0.3 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.6 KII85352.1 - 0.00054 19.4 6.2 4.4 6.6 0.0 5.6 1 1 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Paramyx_P_V_C PF03210.13 KII85352.1 - 0.0031 17.3 1.5 76 3.0 0.0 6.0 8 0 0 8 8 8 0 Paramyxovirus P/V phosphoprotein C-terminal SurE PF01975.17 KII85352.1 - 0.0087 15.9 23.9 0.48 10.2 0.6 6.2 1 1 6 7 7 7 2 Survival protein SurE GspH PF12019.8 KII85352.1 - 0.027 14.9 17.3 10 6.6 0.9 6.3 1 1 1 2 2 2 0 Type II transport protein GspH DUF5319 PF17252.2 KII85352.1 - 0.045 14.0 0.0 12 6.1 0.0 4.0 3 2 2 6 6 5 0 Family of unknown function (DUF5319) DUF1513 PF07433.11 KII85352.1 - 0.052 12.6 14.7 8 5.4 0.2 5.8 1 1 6 7 7 7 0 Protein of unknown function (DUF1513) NACHT PF05729.12 KII85353.1 - 1.3e-10 41.5 0.0 2.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII85353.1 - 7.2e-08 33.0 0.3 4.2e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KII85353.1 - 5.2e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 KII85353.1 - 0.00017 21.6 0.0 0.00056 19.9 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KII85353.1 - 0.0011 18.2 0.0 0.0027 16.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KII85353.1 - 0.0015 18.9 0.1 0.005 17.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII85353.1 - 0.0052 17.1 0.0 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KII85353.1 - 0.014 15.4 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KII85353.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KII85353.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII85353.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1722 PF08349.11 KII85353.1 - 0.11 12.8 0.1 0.35 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) WD40 PF00400.32 KII85358.1 - 9.5e-72 235.1 29.5 2.5e-12 47.1 0.7 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII85358.1 - 2.3e-26 91.9 1.0 0.0089 16.3 0.1 7.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII85358.1 - 1.6e-20 73.4 4.7 0.0028 16.6 0.0 7.2 1 1 6 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KII85358.1 - 3e-18 65.3 4.2 2.3 8.3 0.0 8.5 8 0 0 8 8 8 7 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KII85358.1 - 2.3e-13 50.1 0.0 0.0017 17.8 0.0 5.2 2 2 3 5 5 5 4 WD40-like domain Frtz PF11768.8 KII85358.1 - 2.8e-13 49.1 0.0 0.0046 15.3 0.0 4.6 2 2 2 4 4 4 3 WD repeat-containing and planar cell polarity effector protein Fritz potato_inhibit PF00280.18 KII85358.1 - 4.3e-05 24.1 0.0 22 5.8 0.0 6.0 4 2 3 7 7 7 0 Potato inhibitor I family Cytochrom_D1 PF02239.16 KII85358.1 - 5.1e-05 22.0 3.3 0.1 11.1 0.1 3.5 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 KII85358.1 - 0.001 17.8 9.0 4.9 5.7 0.2 5.4 1 1 4 6 6 6 2 Nucleoporin Nup120/160 Glyco_hydro_30C PF17189.4 KII85358.1 - 0.016 15.4 12.4 33 4.8 0.0 7.2 4 2 4 8 8 8 0 Glycosyl hydrolase family 30 beta sandwich domain TnpW PF14202.6 KII85358.1 - 0.016 15.0 0.0 1.6 8.7 0.0 3.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpW Nbas_N PF15492.6 KII85358.1 - 0.024 14.0 6.1 6.7 6.0 0.1 5.2 1 1 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 KII85358.1 - 0.067 13.2 0.3 1.6e+02 2.4 0.0 4.9 4 2 2 6 6 6 0 WD domain, G-beta repeat DUF3261 PF11659.8 KII85358.1 - 0.16 11.8 0.0 43 4.0 0.0 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3261) NACHT PF05729.12 KII85359.1 - 6.9e-11 42.3 0.0 1.7e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII85359.1 - 6.9e-08 33.1 0.4 3.2e-07 30.9 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 KII85359.1 - 8.8e-05 22.5 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 KII85359.1 - 0.00035 20.6 0.1 0.00082 19.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KII85359.1 - 0.0011 18.2 0.0 0.0031 16.7 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KII85359.1 - 0.0013 19.0 0.0 0.0048 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KII85359.1 - 0.0016 18.8 0.1 0.0052 17.2 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF1722 PF08349.11 KII85359.1 - 0.0065 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) AAA_14 PF13173.6 KII85359.1 - 0.012 15.7 0.1 0.088 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KII85359.1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KII85359.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KII85359.1 - 0.16 11.7 0.3 0.55 9.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KII85359.1 - 0.16 12.0 0.0 2.1 8.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KII85359.1 - 0.16 12.3 0.1 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KII85362.1 - 5e-12 46.1 0.0 6.4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII85362.1 - 3.7e-08 33.7 0.0 5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII85362.1 - 1e-07 31.9 0.0 1.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1744 PF08490.12 KII85363.1 - 2.5e-136 454.4 0.0 3.5e-136 454.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KII85363.1 - 1e-73 248.4 0.0 1.5e-73 247.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KII85363.1 - 3.4e-10 39.2 1.6 1.4e-05 24.0 0.0 4.1 5 0 0 5 5 5 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KII85363.1 - 7.6e-09 35.6 0.1 2.4e-08 33.9 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KII85363.1 - 0.00026 21.0 0.0 0.00081 19.4 0.0 1.8 1 0 0 1 1 1 1 RNase_H superfamily zf-C4pol PF14260.6 KII85363.1 - 0.32 11.5 7.1 1.1 9.8 7.1 1.9 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Fasciclin PF02469.22 KII85364.1 - 5.8e-08 33.0 0.0 0.0024 18.1 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain Ferric_reduct PF01794.19 KII85365.1 - 8.5e-20 71.1 8.0 1e-19 70.9 2.3 3.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KII85365.1 - 2.5e-12 47.2 0.0 3.9e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII85365.1 - 2.5e-06 27.5 0.0 0.084 13.0 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain DUF1860 PF08949.10 KII85365.1 - 0.15 11.8 4.3 0.13 12.0 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) FAD_binding_3 PF01494.19 KII85366.1 - 3.3e-13 49.6 0.0 1.8e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KII85366.1 - 1.2e-05 24.7 2.7 0.0012 18.1 0.6 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KII85366.1 - 1.3e-05 24.7 3.7 0.00049 19.5 0.6 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KII85366.1 - 6.1e-05 22.3 0.1 0.00015 21.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KII85366.1 - 8.4e-05 22.7 1.3 0.0003 20.9 1.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KII85366.1 - 0.0024 18.4 0.5 0.067 13.8 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII85366.1 - 0.0063 15.9 4.3 0.0063 15.9 4.3 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KII85366.1 - 0.007 16.0 4.9 0.02 14.5 1.8 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII85366.1 - 0.025 13.8 0.0 0.92 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII85366.1 - 0.033 12.9 0.5 0.22 10.2 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KII85366.1 - 0.043 13.1 0.1 0.075 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Potex_coat PF06184.11 KII85366.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein GIDA PF01134.22 KII85366.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Mo25 PF08569.11 KII85367.1 - 3.5e-134 447.3 5.1 4e-134 447.1 5.1 1.0 1 0 0 1 1 1 1 Mo25-like HflK_N PF12221.8 KII85367.1 - 0.23 11.5 0.6 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial membrane protein N terminal GST_N PF02798.20 KII85369.1 - 3.4e-14 52.9 0.0 6.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII85369.1 - 3.4e-13 49.6 0.0 7.1e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII85369.1 - 2.3e-11 43.9 0.0 4.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII85369.1 - 2.9e-10 40.3 0.0 6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII85369.1 - 1.7e-08 34.3 0.8 3.2e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII85369.1 - 1.7e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KII85369.1 - 0.09 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein E1-E2_ATPase PF00122.20 KII85370.1 - 3.6e-42 143.9 4.7 8e-42 142.8 4.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KII85370.1 - 3.8e-30 105.8 1.3 3.8e-30 105.8 1.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KII85370.1 - 6e-07 29.8 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KII85370.1 - 0.00039 20.3 0.5 0.0015 18.3 0.5 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KII85370.1 - 0.0011 19.4 0.3 0.0046 17.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 KII85370.1 - 0.096 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 ACT domain NACHT PF05729.12 KII85374.1 - 2.7e-11 43.6 0.0 4.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII85374.1 - 3.7e-06 27.4 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII85374.1 - 0.00038 20.7 0.0 0.0019 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KII85374.1 - 0.00057 19.8 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA PF00004.29 KII85374.1 - 0.0029 18.0 0.1 0.0078 16.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII85374.1 - 0.0059 15.8 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 KII85374.1 - 0.011 15.7 0.1 0.02 14.8 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KII85374.1 - 0.013 14.9 0.1 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 KII85374.1 - 0.063 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 KII85374.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KII85374.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII85374.1 - 0.22 12.1 0.4 0.9 10.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 KII85375.1 - 8.9e-152 488.4 68.5 1.1e-11 45.1 0.4 14.7 15 0 0 15 15 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII85375.1 - 1.5e-57 191.8 11.6 0.0041 17.4 0.0 14.9 2 1 13 15 15 15 14 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII85375.1 - 1.3e-33 116.4 25.0 0.035 13.1 0.1 14.3 1 1 14 15 15 15 13 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KII85375.1 - 7.5e-29 101.0 3.2 0.021 14.2 0.0 12.2 2 2 12 14 14 14 13 WD40-like domain Frtz PF11768.8 KII85375.1 - 7.6e-28 97.1 0.1 0.0014 17.1 0.0 8.7 1 1 4 9 9 9 8 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KII85375.1 - 7.3e-24 83.1 16.7 6.1 6.9 0.0 14.4 14 0 0 14 14 14 10 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KII85375.1 - 4.4e-07 28.8 22.2 0.039 12.5 0.6 6.6 1 1 7 8 8 8 8 Cytochrome D1 heme domain DUF4072 PF13284.6 KII85375.1 - 2.1e-05 24.9 12.7 18 5.8 0.0 9.7 10 1 1 11 11 11 0 Domain of unknown function (DUF4072) SpoIIE PF07228.12 KII85375.1 - 3.1e-05 24.0 0.0 64 3.4 0.0 7.3 3 3 6 9 9 9 0 Stage II sporulation protein E (SpoIIE) DUF5643 PF18705.1 KII85375.1 - 0.00011 22.2 0.6 44 4.1 0.0 6.7 8 1 1 9 9 9 0 Family of unknown function (DUF5643) CDRT4 PF15213.6 KII85375.1 - 0.00017 22.2 3.9 7.5 7.2 0.2 7.1 2 2 3 8 8 8 1 CMT1A duplicated region transcript 4 protein PQQ PF01011.21 KII85375.1 - 0.00048 19.9 25.6 6.4 6.9 0.1 11.6 13 0 0 13 13 13 1 PQQ enzyme repeat WD40_3 PF15911.5 KII85375.1 - 0.0017 18.3 6.2 2.3e+02 1.9 0.0 9.5 12 2 1 13 13 13 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KII85375.1 - 0.35 11.4 24.1 74 4.0 0.1 10.5 13 0 0 13 13 13 0 PQQ-like domain VID27 PF08553.10 KII85375.1 - 0.77 8.7 12.6 17 4.3 0.1 5.0 2 1 3 6 6 6 0 VID27 C-terminal WD40-like domain MAP65_ASE1 PF03999.12 KII85376.1 - 1.1e-67 229.1 3.7 4.6e-62 210.6 0.0 3.6 2 1 1 4 4 4 2 Microtubule associated protein (MAP65/ASE1 family) Synaptobrevin PF00957.21 KII85377.1 - 7.2e-34 115.5 2.7 8.2e-34 115.3 2.7 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF515 PF04415.12 KII85377.1 - 1.8 6.8 6.2 2.1 6.6 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) NAD_binding_4 PF07993.12 KII85378.1 - 2.2e-23 82.7 0.0 3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KII85378.1 - 9.1e-12 44.9 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII85378.1 - 0.0033 16.5 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KII85378.1 - 0.014 15.3 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 KII85378.1 - 0.098 12.5 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding DDT PF02791.17 KII85378.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 DDT domain GDP_Man_Dehyd PF16363.5 KII85378.1 - 0.21 11.0 0.0 0.42 9.9 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII85379.1 - 2.2e-24 86.0 0.0 3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KII85379.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII85379.1 - 9e-05 21.6 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KII85379.1 - 0.0055 16.6 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KII85379.1 - 0.034 13.5 0.2 0.13 11.7 0.2 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KII85379.1 - 0.049 14.1 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KII85380.1 - 8.4e-22 77.6 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KII85380.1 - 6.9e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII85380.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KII85380.1 - 0.05 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 KII85380.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 KII85381.1 - 5.8e-75 252.1 0.0 8.1e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII85381.1 - 3.3e-42 144.6 0.0 4.6e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII85381.1 - 2.5e-12 46.7 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII85381.1 - 0.00098 18.5 1.2 0.0018 17.7 0.3 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KII85381.1 - 0.041 12.8 0.1 0.089 11.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PRTase_2 PF15609.6 KII85381.1 - 0.11 12.0 0.4 0.2 11.1 0.4 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase zf-C2H2_11 PF16622.5 KII85383.1 - 0.061 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-Di19 PF05605.12 KII85383.1 - 0.097 13.0 1.4 0.81 10.0 0.4 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KII85383.1 - 0.88 10.6 8.0 1.6 9.8 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4223 PF13978.6 KII85384.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4223) Ribosomal_L24e PF01246.20 KII85385.1 - 3.7e-30 104.0 0.3 3.7e-30 104.0 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Ets PF00178.22 KII85385.1 - 0.06 13.8 0.5 0.11 13.0 0.5 1.4 1 0 0 1 1 1 0 Ets-domain Acetyltransf_3 PF13302.7 KII85386.1 - 2.1e-11 44.6 0.0 2.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII85386.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 KII85386.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.3 1 1 0 1 1 1 1 GNAT acetyltransferase Transposase_21 PF02992.14 KII85388.1 - 2.1e-10 40.2 0.0 4.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Plavaka PF18759.1 KII85388.1 - 0.0005 19.4 0.1 0.0009 18.6 0.1 1.4 1 0 0 1 1 1 1 Plavaka transposase PUL PF08324.11 KII85388.1 - 0.033 13.4 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 PUL domain ALMS_repeat PF18727.1 KII85389.1 - 0.064 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat FTA2 PF13095.6 KII85389.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PBSX_XtrA PF17356.2 KII85390.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA Glyco_hyd_65N_2 PF14498.6 KII85391.1 - 0.062 13.1 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PBSX_XtrA PF17356.2 KII85391.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA FTA2 PF13095.6 KII85392.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-UBR PF02207.20 KII85393.1 - 2.1e-09 37.4 8.5 2.1e-09 37.4 8.5 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 KII85393.1 - 7.7e-07 28.9 0.6 7.7e-07 28.9 0.6 4.0 4 1 1 5 5 5 1 PHD-finger EF-hand_1 PF00036.32 KII85394.1 - 3.6e-38 126.3 8.9 1.1e-09 37.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KII85394.1 - 1e-32 112.4 1.6 3.4e-15 56.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KII85394.1 - 1.5e-28 96.2 5.3 3.2e-09 36.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KII85394.1 - 2.9e-28 97.5 8.7 8.2e-13 48.0 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KII85394.1 - 1.3e-24 84.5 6.2 3.8e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KII85394.1 - 1.5e-13 50.8 0.1 7.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KII85394.1 - 9.5e-07 28.7 0.7 0.04 13.9 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KII85394.1 - 2.5e-06 27.8 0.1 0.099 13.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KII85394.1 - 8.3e-05 22.5 0.0 0.11 12.6 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KII85394.1 - 0.0003 20.8 0.2 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KII85394.1 - 0.00055 20.8 0.0 0.14 13.0 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 KII85394.1 - 0.002 17.8 1.9 0.0027 17.4 1.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.6 KII85394.1 - 0.0042 17.5 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) Dockerin_1 PF00404.18 KII85394.1 - 0.0051 17.0 6.1 0.14 12.4 1.1 2.9 1 1 2 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 KII85394.1 - 0.0062 16.5 0.4 0.91 9.4 0.2 3.2 1 1 1 2 2 2 1 Caleosin related protein Poly_export PF02563.16 KII85394.1 - 0.011 15.9 0.1 2.1 8.7 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 KII85394.1 - 0.035 14.2 0.0 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 KII85394.1 - 0.039 14.3 0.3 11 6.3 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF3349 PF11829.8 KII85394.1 - 0.044 14.6 0.2 7 7.5 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_14 PF17959.1 KII85394.1 - 0.11 12.9 0.1 20 5.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 KII85394.1 - 0.14 11.8 0.1 0.31 10.7 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain WH1 PF00568.23 KII85395.1 - 3.3e-22 78.5 0.0 4.5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KII85395.1 - 3.8e-05 24.0 0.1 7.7e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 KII85395.1 - 0.002 17.9 0.1 0.0052 16.6 0.1 1.7 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 KII85395.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family RVT_1 PF00078.27 KII85400.1 - 9.7e-05 22.0 0.0 0.0001 21.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KII85402.1 - 7.5e-05 22.9 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RGS PF00615.19 KII85405.1 - 8.7e-10 38.9 1.0 4.6e-05 23.7 0.1 2.5 3 0 0 3 3 3 2 Regulator of G protein signaling domain DUF4199 PF13858.6 KII85405.1 - 1.1 9.6 6.6 2.3 8.6 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) L51_S25_CI-B8 PF05047.16 KII85406.1 - 1.3e-13 50.6 0.0 4.9e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 KII85406.1 - 0.05 12.9 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Polyketide_cyc2 PF10604.9 KII85407.1 - 4.1e-07 30.4 0.3 3.3e-06 27.4 0.2 2.0 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KII85407.1 - 0.0011 19.1 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1218 PF06749.12 KII85408.1 - 0.41 11.2 10.0 0.98 10.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) SGL PF08450.12 KII85409.1 - 2.2e-25 89.7 0.1 3.9e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KII85409.1 - 0.0013 18.9 0.0 0.0055 16.9 0.0 2.1 1 0 0 1 1 1 1 Arylesterase Dynamin_N PF00350.23 KII85410.1 - 1.1e-13 51.6 0.1 3.6e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KII85410.1 - 1.2e-05 25.3 0.0 0.00087 19.4 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII85410.1 - 0.0002 21.3 0.1 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KII85410.1 - 0.00039 20.9 0.0 0.0019 18.7 0.0 2.3 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.16 KII85410.1 - 0.015 14.7 0.8 4.2 6.6 0.2 2.6 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 KII85410.1 - 0.026 14.8 0.3 0.29 11.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 KII85410.1 - 0.045 12.8 0.0 2.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 KII85410.1 - 0.064 13.6 0.1 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KII85410.1 - 0.091 13.3 3.4 0.23 11.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain CelTOS PF18659.1 KII85410.1 - 0.18 12.3 0.7 0.59 10.6 0.7 1.9 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites SGL PF08450.12 KII85411.1 - 8.2e-28 97.6 0.0 1.2e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KII85411.1 - 0.0024 18.0 0.2 0.0099 16.1 0.0 2.1 2 1 0 2 2 2 1 Arylesterase Str_synth PF03088.16 KII85411.1 - 0.015 15.4 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase DDE_1 PF03184.19 KII85412.1 - 1e-13 51.3 0.1 3.7e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KII85412.1 - 0.014 15.4 0.1 0.038 14.0 0.1 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain REJ PF02010.15 KII85413.1 - 0.026 13.3 0.0 0.031 13.1 0.0 1.0 1 0 0 1 1 1 0 REJ domain FA_desaturase PF00487.24 KII85414.1 - 4.6e-17 62.7 19.8 4.6e-17 62.7 19.8 1.8 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII85414.1 - 5e-12 45.8 0.0 9.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NSs PF11073.8 KII85414.1 - 0.0041 16.6 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Rift valley fever virus non structural protein (NSs) like DUF4685 PF15737.5 KII85415.1 - 0.17 12.3 5.4 0.32 11.5 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) ORC6 PF05460.13 KII85415.1 - 4.8 6.3 13.8 0.55 9.4 9.7 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) APH PF01636.23 KII85420.1 - 1.8e-13 51.0 0.6 1.8e-13 51.0 0.6 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII85420.1 - 0.00052 19.7 0.0 0.00067 19.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KII85420.1 - 0.0097 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family zf-Di19 PF05605.12 KII85422.1 - 0.0067 16.7 2.0 0.0067 16.7 2.0 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KII85422.1 - 0.028 14.9 10.9 0.24 11.9 3.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85422.1 - 0.043 14.7 2.7 0.043 14.7 2.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KII85422.1 - 0.046 13.6 0.6 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 KII85422.1 - 0.93 9.6 7.2 0.8 9.8 4.5 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_12 PF18658.1 KII85422.1 - 2.9 7.5 4.7 2.6 7.7 0.1 2.5 2 1 1 3 3 3 0 Zinc-finger C2H2-type FOXP-CC PF16159.5 KII85422.1 - 4.8 7.9 5.8 2.7 8.7 1.9 2.4 2 1 0 2 2 2 0 FOXP coiled-coil domain APH PF01636.23 KII85423.1 - 0.077 12.9 0.0 0.096 12.6 0.0 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family RPN13_C PF16550.5 KII85424.1 - 7.2e-05 22.9 2.9 58 3.9 0.0 5.8 5 1 1 6 6 6 2 UCH-binding domain SOG2 PF10428.9 KII85424.1 - 7.7 5.6 6.5 16 4.5 6.5 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4503 PF14951.6 KII85427.1 - 0.032 12.7 0.1 0.034 12.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) LPG_synthase_TM PF03706.13 KII85428.1 - 0.19 11.3 1.0 0.23 10.9 1.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region HIRAN PF08797.11 KII85429.1 - 8.4e-05 22.4 0.1 3.1 7.8 0.5 4.6 2 2 0 2 2 2 2 HIRAN domain Antimicrobial_7 PF08102.11 KII85429.1 - 0.00095 19.4 4.8 13 6.1 0.0 7.1 6 1 1 7 7 7 1 Scorpion antimicrobial peptide Beta_helix PF13229.6 KII85429.1 - 0.009 15.9 44.8 0.13 12.1 14.4 3.7 1 1 2 3 3 3 2 Right handed beta helix region HD PF01966.22 KII85429.1 - 0.012 15.9 13.1 37 4.6 0.0 7.1 3 3 3 6 6 6 0 HD domain Hydrophobin_2 PF06766.11 KII85429.1 - 0.12 12.4 0.5 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Fungal hydrophobin DUF3408 PF11888.8 KII85429.1 - 2.4 8.3 3.9 7.8 6.6 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3408) Bacteriocin_IIi PF11758.8 KII85430.1 - 0.013 15.3 5.7 17 5.3 0.1 4.7 1 1 4 5 5 5 0 Aureocin-like type II bacteriocin Tht1 PF04163.12 KII85430.1 - 0.14 10.9 0.5 0.18 10.5 0.5 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein NosD PF05048.13 KII85430.1 - 4 6.6 16.7 9.8 5.4 16.7 1.6 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Oxidored_FMN PF00724.20 KII85431.1 - 1.5e-66 225.0 0.0 1.9e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAT PF04768.13 KII85432.1 - 3.4e-45 153.7 0.0 5.2e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KII85432.1 - 8.4e-29 100.5 0.0 1.8e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KII85432.1 - 1.1e-24 87.4 0.2 2.5e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family Metallophos PF00149.28 KII85433.1 - 2.3e-36 126.2 0.1 3.8e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.26 KII85434.1 - 6.8e-47 158.6 0.0 8.4e-47 158.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KII85434.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KII85434.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KII85434.1 - 0.04 14.2 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Skp1_POZ PF03931.15 KII85435.1 - 0.00052 20.1 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Glyco_hydro_92 PF07971.12 KII85438.1 - 4.9e-118 395.0 0.0 5.9e-118 394.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KII85438.1 - 1e-46 159.8 3.0 1.7e-46 159.0 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain zf-RING_2 PF13639.6 KII85440.1 - 1.5e-13 50.9 6.1 2.1e-13 50.4 6.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII85440.1 - 1.5e-09 37.8 3.6 2.7e-09 36.9 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII85440.1 - 7.7e-08 32.0 6.5 1.3e-07 31.4 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85440.1 - 1.6e-07 31.1 4.5 2.2e-07 30.6 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII85440.1 - 8.8e-07 28.7 3.8 1.5e-06 28.0 3.8 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85440.1 - 1.3e-06 28.2 3.1 1.9e-06 27.7 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KII85440.1 - 8.7e-06 25.4 0.7 8.7e-06 25.4 0.7 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KII85440.1 - 1.9e-05 24.9 11.9 8.1e-05 22.8 11.1 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KII85440.1 - 0.00038 20.3 10.4 0.00063 19.5 4.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 KII85440.1 - 0.00049 20.2 6.9 0.00088 19.4 6.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 KII85440.1 - 0.00076 19.5 6.1 0.0035 17.3 6.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KII85440.1 - 0.0022 17.8 3.7 0.0056 16.4 3.6 1.7 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain PHD PF00628.29 KII85440.1 - 0.017 15.0 5.7 0.052 13.4 5.2 1.9 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 KII85440.1 - 0.073 13.0 3.7 0.75 9.8 0.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Tmpp129 PF10272.9 KII85440.1 - 0.38 10.0 2.7 0.16 11.2 0.5 1.4 2 0 0 2 2 2 0 Putative transmembrane protein precursor FANCL_C PF11793.8 KII85440.1 - 0.53 10.5 11.3 31 4.9 11.3 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KII85440.1 - 0.58 10.5 7.1 0.19 12.1 3.4 1.9 2 0 0 2 2 2 0 RING-like domain zf-P11 PF03854.14 KII85440.1 - 1.2 8.9 8.0 0.3 10.8 1.9 2.1 1 1 0 2 2 2 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KII85440.1 - 4.8 6.9 12.3 6 6.6 11.0 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Hydantoinase_B PF02538.14 KII85442.1 - 5.1e-209 695.0 0.3 5.8e-209 694.8 0.3 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Glyco_hydro_71 PF03659.14 KII85444.1 - 4.4e-121 404.2 8.3 5e-121 404.1 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 zf-H2C2_2 PF13465.6 KII85446.1 - 5.7e-10 39.2 10.5 1.6e-07 31.5 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 KII85446.1 - 2.1e-08 33.8 14.0 0.0003 20.5 0.1 4.2 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KII85446.1 - 4.6e-08 33.1 16.3 0.0032 17.8 0.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85446.1 - 0.0032 18.2 13.5 2.4 9.2 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger Zap1_zf2 PF18217.1 KII85446.1 - 1.1 9.3 3.6 1.2 9.1 0.0 2.8 4 0 0 4 4 4 0 Zap1 zinc finger 2 OrsD PF12013.8 KII85446.1 - 1.2 9.6 8.3 2.5e+02 2.1 8.3 2.9 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Glyco_hydro_71 PF03659.14 KII85447.1 - 1.4e-130 435.5 2.8 1.6e-130 435.3 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 VirB7 PF17413.2 KII85447.1 - 0.032 13.6 0.0 0.077 12.3 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 VHS PF00790.19 KII85448.1 - 8.3e-38 129.4 0.0 3.4e-37 127.4 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KII85448.1 - 4.4e-20 71.8 0.5 3e-19 69.1 0.1 2.6 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KII85448.1 - 0.0038 16.8 0.1 0.01 15.4 0.1 1.7 1 0 0 1 1 1 1 GGA N-GAT domain HMG_box PF00505.19 KII85450.1 - 1.1e-14 54.5 7.4 1.5e-06 28.6 0.5 3.2 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KII85450.1 - 5.5e-09 36.5 4.5 6.3e-06 26.7 0.4 2.8 2 0 0 2 2 2 2 HMG-box domain MlaC PF05494.12 KII85450.1 - 5.2 6.8 8.6 4.4 7.0 0.3 2.7 3 0 0 3 3 3 0 MlaC protein DUF3106 PF11304.8 KII85450.1 - 9.5 6.8 15.2 2.2 8.8 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) zf-H2C2_5 PF13909.6 KII85451.1 - 9.4e-10 38.1 7.0 0.00025 20.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KII85451.1 - 3e-07 30.5 17.3 0.016 15.7 3.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85451.1 - 1.4e-06 28.6 14.0 0.1 13.5 1.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII85451.1 - 1.7e-05 25.0 0.7 1.7e-05 25.0 0.7 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KII85451.1 - 0.0076 16.0 3.9 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-RRPl_C4 PF17026.5 KII85451.1 - 0.053 13.6 0.6 0.08 13.1 0.6 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Di19 PF05605.12 KII85451.1 - 0.37 11.1 9.2 0.18 12.1 3.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 KII85451.1 - 7.4 7.0 7.4 0.74 10.2 0.8 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_71 PF03659.14 KII85452.1 - 3.9e-129 430.7 1.9 4.8e-129 430.4 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 ThiF PF00899.21 KII85453.1 - 1.7e-71 240.4 0.1 2.4e-71 240.0 0.1 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KII85453.1 - 1.2e-15 58.1 0.1 7.4e-14 52.3 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KII85453.1 - 1.1e-06 29.1 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KII85453.1 - 0.00049 20.5 0.0 0.0049 17.3 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 KII85453.1 - 0.068 13.6 0.1 5.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA_13 PF13166.6 KII85453.1 - 0.24 10.0 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KII85455.1 - 3.7e-23 82.4 0.0 6.2e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KII85455.1 - 3.1e-06 27.7 0.0 8e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KII85455.1 - 0.017 15.5 0.1 0.042 14.3 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 KII85455.1 - 0.039 14.3 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA_30 PF13604.6 KII85455.1 - 0.051 13.3 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KII85455.1 - 0.062 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KII85455.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DnaJ_C PF01556.18 KII85456.1 - 2.7e-26 92.4 0.0 3.4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KII85456.1 - 0.00018 21.8 6.6 0.00063 20.1 0.8 2.3 2 0 0 2 2 2 2 DnaJ central domain zf_CopZ PF18423.1 KII85456.1 - 0.38 10.7 2.1 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc binding domain DnaJ_C PF01556.18 KII85458.1 - 1.5e-19 70.6 0.0 1.8e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KII85458.1 - 3.6e-07 30.4 12.9 6.4e-07 29.6 12.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KII85458.1 - 0.005 16.8 16.8 0.0081 16.1 1.4 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein A2L_zn_ribbon PF08792.10 KII85458.1 - 0.0067 16.1 1.8 0.0067 16.1 1.8 2.6 2 1 1 3 3 3 1 A2L zinc ribbon domain HypA PF01155.19 KII85458.1 - 1 9.4 7.9 4.7 7.3 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 KII85458.1 - 2.2 8.5 9.8 0.82 9.8 0.6 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) 3-HAO PF06052.12 KII85459.1 - 1.8e-59 199.7 0.0 2e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KII85459.1 - 1.7e-06 27.6 0.2 3.2e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KII85459.1 - 0.00059 19.8 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain F-box-like PF12937.7 KII85460.1 - 7.9e-06 25.7 1.6 6.3e-05 22.8 1.6 2.4 1 1 0 1 1 1 1 F-box-like YL1_C PF08265.11 KII85461.1 - 1.5e-15 56.6 0.4 2.7e-15 55.8 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BING4CT PF08149.11 KII85462.1 - 7.6e-38 128.2 0.2 1.7e-36 123.8 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KII85462.1 - 7.3e-06 26.6 0.1 0.00077 20.2 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.6 KII85462.1 - 0.012 15.2 0.0 0.051 13.1 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KII85462.1 - 0.031 14.6 0.0 2.5 8.4 0.0 3.4 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KII85462.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 KII85462.1 - 0.17 10.4 0.0 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Glyoxal_oxid_N PF07250.11 KII85463.1 - 8.7e-35 120.0 0.2 8.2e-17 61.2 0.0 4.9 4 1 1 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KII85463.1 - 3.8e-24 84.8 0.3 8e-24 83.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KII85463.1 - 0.029 14.4 9.2 0.14 12.1 0.2 4.2 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF2561 PF10812.8 KII85463.1 - 0.035 14.1 0.2 0.059 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) AlaDh_PNT_C PF01262.21 KII85463.1 - 0.17 11.2 5.1 0.39 10.0 3.2 2.3 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SKG6 PF08693.10 KII85463.1 - 0.17 11.3 3.0 0.34 10.4 3.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_6 PF13964.6 KII85463.1 - 0.97 9.8 7.4 17 5.8 0.1 4.3 4 0 0 4 4 4 0 Kelch motif Hyd_WA PF06462.12 KII85464.1 - 0.082 12.9 0.1 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Propeller Pkinase PF00069.25 KII85465.1 - 1.9e-05 24.2 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII85465.1 - 0.00094 19.2 0.8 0.0077 16.2 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII85465.1 - 0.0089 15.4 0.0 0.089 12.1 0.0 2.0 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII85465.1 - 0.09 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CPL PF08144.11 KII85467.1 - 6.8e-35 120.5 0.0 3e-31 108.7 0.0 3.7 3 0 0 3 3 3 2 CPL (NUC119) domain Utp13 PF08625.11 KII85467.1 - 0.0029 17.5 0.1 0.0099 15.8 0.1 2.0 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain DUF1749 PF08538.10 KII85467.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) YqcI_YcgG PF08892.11 KII85467.1 - 0.12 12.2 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 YqcI/YcgG family zf-MYND PF01753.18 KII85468.1 - 3e-09 36.8 10.8 5.9e-09 35.9 10.8 1.5 1 0 0 1 1 1 1 MYND finger Mrr_cat_2 PF13156.6 KII85468.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease zf-C6H2 PF15801.5 KII85468.1 - 1.6 9.1 9.5 3.7 7.9 9.5 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Dna2 PF08696.11 KII85469.1 - 8.1e-57 192.3 0.0 1.8e-56 191.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KII85469.1 - 2.4e-50 171.0 0.0 4.1e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII85469.1 - 2.2e-15 57.1 0.0 3.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII85469.1 - 5.4e-09 36.0 0.0 1.5e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII85469.1 - 7e-07 29.7 0.0 2e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 KII85469.1 - 0.001 19.1 0.1 0.29 11.0 0.0 2.6 3 0 0 3 3 3 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 KII85469.1 - 0.0024 18.0 0.7 0.11 12.6 0.7 2.6 1 1 0 1 1 1 1 Domain of unknown function DUF83 UvrD-helicase PF00580.21 KII85469.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KII85469.1 - 0.013 15.3 0.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Whib PF02467.16 KII85469.1 - 0.017 15.7 1.1 8.7 7.0 0.1 2.7 2 0 0 2 2 2 0 Transcription factor WhiB AAA_16 PF13191.6 KII85469.1 - 0.022 15.2 0.4 0.081 13.3 0.0 2.2 2 0 0 2 2 1 0 AAA ATPase domain AAA PF00004.29 KII85469.1 - 0.025 15.0 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KII85469.1 - 0.025 14.6 0.1 0.058 13.5 0.1 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KII85469.1 - 0.028 14.0 0.4 0.058 13.0 0.2 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KII85469.1 - 0.042 14.0 0.0 0.22 11.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KII85469.1 - 0.043 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KII85469.1 - 0.062 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.14 KII85469.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_18 PF13238.6 KII85469.1 - 0.075 13.6 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KII85469.1 - 0.17 11.4 0.1 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Flavin_Reduct PF01613.18 KII85470.1 - 1.9e-18 67.0 0.0 2.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain CHZ PF09649.10 KII85471.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ Myosin_head PF00063.21 KII85472.1 - 9.8e-257 853.6 0.0 3.3e-256 851.8 0.0 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Ribosomal_L38e PF01781.18 KII85472.1 - 4.2e-32 110.1 0.4 4.2e-32 110.1 0.4 2.3 2 0 0 2 2 2 1 Ribosomal L38e protein family Myosin_tail_1 PF01576.19 KII85472.1 - 3.4e-29 101.4 293.0 2.7e-13 48.7 141.0 6.0 1 1 4 6 6 6 6 Myosin tail Myosin_N PF02736.19 KII85472.1 - 1.2e-08 34.6 2.8 3.6e-08 33.1 2.8 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KII85472.1 - 0.054 13.8 0.0 0.054 13.8 0.0 4.9 4 0 0 4 4 4 0 AAA domain IQ PF00612.27 KII85472.1 - 4.7 7.3 5.7 0.97 9.4 0.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF2569 PF10754.9 KII85476.1 - 2.4 8.6 10.0 0.48 10.9 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Gaa1 PF04114.14 KII85477.1 - 0.055 12.5 2.2 0.064 12.3 2.2 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component SUa-2TM PF18179.1 KII85477.1 - 0.06 12.6 0.2 0.085 12.1 0.2 1.1 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain SUR7 PF06687.12 KII85477.1 - 0.073 12.7 7.7 4.3 6.9 8.1 2.6 2 1 0 2 2 2 0 SUR7/PalI family DUF4199 PF13858.6 KII85477.1 - 0.15 12.5 2.7 0.18 12.2 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2463 PF09591.10 KII85477.1 - 0.69 9.8 8.3 0.37 10.6 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) DUF4064 PF13273.6 KII85477.1 - 9 6.6 9.8 10 6.5 2.6 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF4064) DUF3483 PF11982.8 KII85478.1 - 0.041 13.5 3.0 0.096 12.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) Ubie_methyltran PF01209.18 KII85479.1 - 1.7e-05 24.3 0.0 0.00084 18.7 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KII85479.1 - 3.2e-05 24.6 0.0 0.00044 20.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85479.1 - 0.002 18.7 0.0 0.011 16.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII85479.1 - 0.016 15.0 0.0 0.13 12.1 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 KII85479.1 - 0.21 11.3 0.0 2.6 7.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KII85480.1 - 7.7e-05 22.6 0.0 0.00039 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII85480.1 - 0.00016 22.3 0.0 0.0003 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85480.1 - 0.00027 21.5 0.0 0.0005 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII85480.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KII85480.1 - 0.053 13.3 0.0 0.067 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KII85480.1 - 0.059 14.1 0.0 0.094 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KII85481.1 - 2.9e-10 40.7 0.0 6.8e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII85481.1 - 4.9e-08 33.0 0.0 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85481.1 - 8.7e-06 26.3 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII85481.1 - 9.6e-06 25.1 0.0 3.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KII85481.1 - 4.7e-05 23.2 0.0 0.0003 20.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII85481.1 - 0.00093 19.9 0.0 0.002 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain ORC5_C PF14630.6 KII85482.1 - 6.3e-65 219.5 0.0 8.7e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus ArnB_C PF18677.1 KII85482.1 - 0.27 11.4 0.1 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain BTB PF00651.31 KII85483.1 - 4.7e-05 23.6 0.0 8.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SOG2 PF10428.9 KII85483.1 - 0.073 12.3 9.1 0.095 11.9 9.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KII85483.1 - 0.21 10.3 3.0 0.23 10.1 3.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pyr_redox_2 PF07992.14 KII85484.1 - 2e-64 217.7 6.2 2.8e-64 217.2 6.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KII85484.1 - 1.1e-42 144.8 2.9 3.6e-41 139.8 0.1 2.9 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KII85484.1 - 7.2e-21 74.5 9.3 1.6e-18 67.0 1.5 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII85484.1 - 3.8e-11 42.7 0.7 3.8e-11 42.7 0.7 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KII85484.1 - 1.1e-10 41.5 14.1 3.2e-10 40.0 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII85484.1 - 7.9e-10 38.8 2.5 6.1e-05 23.2 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII85484.1 - 8.9e-10 38.3 5.9 1.5e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII85484.1 - 3.8e-07 29.6 0.5 0.015 14.5 0.1 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KII85484.1 - 9.4e-07 28.2 2.3 9.4e-07 28.2 2.3 3.6 2 1 1 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 KII85484.1 - 2.8e-06 26.8 4.2 0.007 15.7 0.6 3.5 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KII85484.1 - 3.1e-06 26.2 15.0 0.00038 19.3 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KII85484.1 - 0.00044 19.6 4.0 0.0023 17.2 0.2 2.5 3 0 0 3 3 3 1 Thi4 family THF_DHG_CYH_C PF02882.19 KII85484.1 - 0.0016 17.8 1.7 0.024 13.9 0.1 2.8 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 KII85484.1 - 0.0021 17.4 10.9 0.096 11.9 0.6 3.5 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 KII85484.1 - 0.0022 17.7 15.7 0.64 9.5 0.2 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KII85484.1 - 0.68 10.4 2.2 1.8 9.0 0.2 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KII85484.1 - 0.71 8.9 5.7 1.1 8.3 0.1 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KII85484.1 - 1.6 8.6 7.2 0.081 12.8 1.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 KII85486.1 - 4.6e-44 150.8 0.0 1.5e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII85486.1 - 3.6e-25 88.7 0.0 2.8e-21 76.0 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KII85486.1 - 3.2e-06 27.3 0.1 0.021 14.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII85486.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII85486.1 - 0.0014 18.0 0.1 0.48 9.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.32 KII85487.1 - 2.6e-08 34.4 0.1 0.061 14.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 KII85487.1 - 2.2e-06 27.4 2.4 2.5e-05 24.1 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII85487.1 - 4.7e-05 23.2 0.8 0.00036 20.3 0.1 2.4 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KII85487.1 - 0.074 13.4 0.1 4.7 7.6 0.0 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KII85490.1 - 2.8e-64 217.6 0.0 6.9e-64 216.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KII85491.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII85491.1 - 0.00093 19.2 1.0 0.026 14.5 0.4 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII85491.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase GPI-anchored PF10342.9 KII85492.1 - 6.9e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Beach PF02138.18 KII85493.1 - 1.6e-106 355.7 0.0 2.6e-106 355.0 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KII85493.1 - 5.9e-08 32.7 0.0 1.5e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KII85493.1 - 2.2e-06 27.9 0.6 9.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 KII85493.1 - 4.8e-05 22.7 0.3 4.8e-05 22.7 0.3 3.8 5 1 0 5 5 5 1 Domain of unknown function (DUF4704) WD40 PF00400.32 KII85493.1 - 0.0006 20.6 1.4 2.6 9.1 0.0 4.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4800 PF16057.5 KII85493.1 - 0.0099 15.2 3.2 0.022 14.1 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) DUF3517 PF12030.8 KII85493.1 - 0.046 12.6 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Cas3_C PF18395.1 KII85493.1 - 0.073 13.6 0.4 9.3 6.8 0.0 3.2 2 0 0 2 2 2 0 Cas3 C-terminal domain Pkinase PF00069.25 KII85494.1 - 5.3e-37 127.6 0.0 2e-36 125.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII85494.1 - 1.4e-12 47.5 0.0 3.1e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII85494.1 - 0.00021 21.3 1.2 0.00079 19.4 0.3 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII85494.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII85494.1 - 0.013 14.9 0.0 0.93 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Aldo_ket_red PF00248.21 KII85495.1 - 6.9e-48 163.3 0.0 4.1e-39 134.5 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family adh_short PF00106.25 KII85496.1 - 6.8e-27 94.2 0.0 1.9e-26 92.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII85496.1 - 5.5e-15 55.6 0.0 8.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KII85496.1 - 0.00058 19.3 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TT_ORF2 PF02957.15 KII85497.1 - 0.075 14.0 0.1 0.15 13.0 0.1 1.4 1 0 0 1 1 1 0 TT viral ORF2 Suc_Fer-like PF06999.12 KII85498.1 - 1.1e-25 90.7 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like KLRAQ PF10205.9 KII85500.1 - 0.0081 16.4 0.2 0.0081 16.4 0.2 3.5 4 0 0 4 4 4 2 Predicted coiled-coil domain-containing protein Fib_alpha PF08702.10 KII85500.1 - 1.2 9.3 3.8 1.5 9.0 1.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tup_N PF08581.10 KII85500.1 - 1.5 9.2 6.9 2.1 8.7 0.2 3.1 3 0 0 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 KII85500.1 - 3.5 7.7 6.8 15 5.6 0.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 KII85500.1 - 3.8 7.8 14.3 4 7.7 1.6 3.0 2 0 0 2 2 2 0 Tho complex subunit 7 YabA PF06156.13 KII85500.1 - 5 7.8 12.8 1.6 9.4 0.1 3.8 3 1 1 4 4 4 0 Initiation control protein YabA Hemerythrin PF01814.23 KII85501.1 - 1.8e-11 44.8 0.3 4.2e-11 43.6 0.3 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain YCII PF03795.14 KII85502.1 - 2.9e-11 43.6 0.0 3.4e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF3098 PF11297.8 KII85502.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3098) Hepatitis_core PF00906.20 KII85503.1 - 1.2 8.6 8.3 2.4 7.7 8.3 1.4 1 0 0 1 1 1 0 Hepatitis core antigen THRAP3_BCLAF1 PF15440.6 KII85503.1 - 7 5.5 9.8 9.4 5.1 9.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Profilin PF00235.19 KII85504.1 - 1.7e-44 151.1 0.4 1.9e-44 151.0 0.4 1.0 1 0 0 1 1 1 1 Profilin DUF2020 PF09449.10 KII85504.1 - 0.22 11.4 1.1 0.4 10.5 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2020) DUF373 PF04123.13 KII85506.1 - 7.1 6.0 8.1 9.4 5.6 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TIM PF00121.18 KII85507.1 - 9.7e-88 293.6 0.0 1.1e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ABC_membrane PF00664.23 KII85509.1 - 2.3e-63 214.4 32.1 8.2e-37 127.3 12.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII85509.1 - 3.1e-53 179.9 0.0 2.6e-29 102.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII85509.1 - 9.1e-10 38.3 2.6 0.007 15.8 0.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KII85509.1 - 2e-09 37.5 0.6 0.0035 17.4 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KII85509.1 - 1.6e-07 31.9 0.2 0.019 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KII85509.1 - 2.6e-07 30.8 0.1 0.041 13.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII85509.1 - 9.6e-07 28.5 0.0 0.051 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KII85509.1 - 2.5e-06 27.5 0.6 0.042 13.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 KII85509.1 - 8.1e-06 26.5 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KII85509.1 - 3.3e-05 24.0 4.3 0.029 14.4 0.3 3.4 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.6 KII85509.1 - 3.7e-05 24.0 0.7 0.37 11.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KII85509.1 - 0.00011 21.6 0.7 0.45 9.7 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 KII85509.1 - 0.00018 21.7 0.1 0.97 9.5 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain DUF815 PF05673.13 KII85509.1 - 0.00024 20.3 0.4 0.08 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KII85509.1 - 0.00034 20.0 0.1 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Roc PF08477.13 KII85509.1 - 0.0022 18.2 0.1 4.3 7.6 0.1 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KII85509.1 - 0.003 17.5 0.3 0.74 9.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.14 KII85509.1 - 0.0043 17.0 0.2 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 KII85509.1 - 0.0044 16.0 0.2 0.5 9.2 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 KII85509.1 - 0.0048 16.7 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.19 KII85509.1 - 0.0055 16.3 0.7 0.71 9.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KII85509.1 - 0.0067 15.6 0.7 2.3 7.3 0.0 3.1 4 0 0 4 4 4 1 NB-ARC domain AAA_25 PF13481.6 KII85509.1 - 0.0094 15.5 0.2 0.39 10.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KII85509.1 - 0.02 14.5 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 KII85509.1 - 0.03 13.3 0.6 5.2 6.0 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KII85509.1 - 0.035 13.6 0.1 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KII85509.1 - 0.044 13.5 0.2 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 KII85509.1 - 0.052 12.8 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KII85509.1 - 0.052 14.1 0.0 11 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 KII85509.1 - 0.063 13.5 0.0 7.1 6.9 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KII85509.1 - 0.072 13.5 0.1 24 5.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 KII85509.1 - 0.086 12.5 5.9 3.2 7.4 0.1 2.9 3 1 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KII85509.1 - 0.095 12.6 0.0 0.82 9.5 0.0 2.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KII85509.1 - 0.11 12.5 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 KII85509.1 - 0.14 11.6 0.2 6.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein zf-RING_2 PF13639.6 KII85511.1 - 3.8e-08 33.5 9.6 3.8e-08 33.5 9.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII85511.1 - 1.7e-07 31.0 6.3 3.7e-07 29.9 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85511.1 - 3.3e-07 30.2 8.0 5.9e-07 29.3 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII85511.1 - 1.2e-06 28.4 3.5 5.8e-06 26.2 3.8 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KII85511.1 - 5.2e-06 26.2 7.8 1.2e-05 25.0 7.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KII85511.1 - 0.00014 21.6 8.9 0.00033 20.4 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85511.1 - 0.00016 21.5 7.8 0.00035 20.4 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KII85511.1 - 0.00047 19.6 0.6 0.00047 19.6 0.6 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger APG17 PF04108.12 KII85511.1 - 0.00054 19.2 1.5 0.00082 18.6 1.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 zf-RING_4 PF14570.6 KII85511.1 - 0.00055 19.7 6.0 0.001 18.8 6.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KII85511.1 - 0.00066 19.8 7.1 0.0022 18.1 7.1 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-met PF12874.7 KII85511.1 - 0.0075 16.6 0.1 0.0075 16.6 0.1 2.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-rbx1 PF12678.7 KII85511.1 - 0.026 14.8 5.8 0.026 14.8 5.8 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain Mvb12 PF09452.10 KII85511.1 - 0.11 12.9 5.1 4.9 7.6 0.1 3.1 1 1 2 3 3 3 0 ESCRT-I subunit Mvb12 Muted PF14942.6 KII85511.1 - 0.12 12.7 1.9 0.16 12.3 1.9 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ApoLp-III PF07464.11 KII85511.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1272 PF06906.11 KII85511.1 - 0.19 11.9 4.3 0.25 11.4 2.9 2.0 3 0 0 3 3 1 0 Protein of unknown function (DUF1272) Laminin_EGF PF00053.24 KII85511.1 - 0.22 11.7 4.4 4.1 7.6 0.9 2.6 1 1 1 2 2 2 0 Laminin EGF domain FYVE PF01363.21 KII85511.1 - 0.27 11.4 6.4 0.4 10.9 2.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger DUF4200 PF13863.6 KII85511.1 - 0.61 10.5 4.3 2.4 8.6 4.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) zf-RING_5 PF14634.6 KII85514.1 - 2e-09 37.3 7.6 3.8e-09 36.3 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII85514.1 - 6.3e-08 32.8 8.5 1.5e-07 31.6 8.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII85514.1 - 9.2e-08 32.0 6.4 3.1e-07 30.3 3.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII85514.1 - 2.8e-07 30.3 6.8 7.1e-07 29.0 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII85514.1 - 1.2e-06 28.3 8.3 3.6e-06 26.7 8.3 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KII85514.1 - 1.3e-05 24.9 8.7 2.9e-05 23.8 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85514.1 - 0.00016 21.5 9.0 0.00043 20.1 9.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII85514.1 - 0.00042 20.4 8.1 0.005 17.0 8.6 2.6 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Tropomyosin PF00261.20 KII85514.1 - 0.0012 18.3 3.7 0.0012 18.3 3.7 1.7 2 0 0 2 2 2 1 Tropomyosin FYVE PF01363.21 KII85514.1 - 0.0018 18.3 1.0 0.0018 18.3 1.0 2.5 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_4 PF14570.6 KII85514.1 - 0.0024 17.6 6.2 0.006 16.4 6.2 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF2239 PF09998.9 KII85514.1 - 0.0087 15.9 0.3 0.012 15.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2239) Baculo_IE-1 PF05290.11 KII85514.1 - 0.018 15.0 2.4 0.018 15.0 2.4 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 KII85514.1 - 0.021 14.2 5.8 0.044 13.2 5.8 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger DUF1272 PF06906.11 KII85514.1 - 0.022 14.8 7.1 0.49 10.5 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Rad50_zn_hook PF04423.14 KII85514.1 - 0.046 13.6 1.1 0.13 12.2 1.1 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF2256 PF10013.9 KII85514.1 - 0.076 13.1 2.2 8.4 6.6 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 KII85514.1 - 0.076 13.5 0.1 0.076 13.5 0.1 2.5 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain DUF3039 PF11238.8 KII85514.1 - 0.078 12.7 2.3 0.17 11.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-rbx1 PF12678.7 KII85514.1 - 0.092 13.1 10.3 0.11 12.8 8.5 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger domain PEP-utilisers_N PF05524.13 KII85514.1 - 0.12 12.6 1.3 0.22 11.7 1.3 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-RING_6 PF14835.6 KII85514.1 - 0.21 11.5 5.1 0.096 12.6 1.5 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KII85514.1 - 0.23 11.2 4.0 0.98 9.2 3.3 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KII85514.1 - 1.1 9.5 8.6 2.3 8.4 5.5 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Arm-DNA-bind_4 PF14657.6 KII85515.1 - 0.19 11.5 0.7 0.28 10.9 0.7 1.2 1 0 0 1 1 1 0 Arm DNA-binding domain Acyltransferase PF01553.21 KII85516.1 - 1.4e-12 47.4 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase LOH1CR12 PF10158.9 KII85516.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Pox_C4_C10 PF03336.13 KII85516.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Ribosomal_S11 PF00411.19 KII85517.1 - 6e-46 155.4 1.6 7.5e-46 155.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 RRM_1 PF00076.22 KII85518.1 - 1.4e-51 172.1 0.0 2.1e-14 53.1 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII85518.1 - 6.9e-07 29.3 0.0 0.24 11.5 0.0 4.1 5 0 0 5 5 5 2 RNA recognition motif RRM_Rrp7 PF17799.1 KII85518.1 - 0.013 15.3 0.0 9.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain ABC_membrane PF00664.23 KII85519.1 - 3.4e-64 217.2 32.4 1.7e-35 123.0 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII85519.1 - 1.5e-53 181.0 0.0 1.4e-30 106.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII85519.1 - 1.1e-09 38.1 2.4 0.0043 16.5 0.1 4.3 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KII85519.1 - 2.5e-09 37.2 0.2 0.004 17.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KII85519.1 - 2.2e-07 31.4 0.1 0.01 16.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KII85519.1 - 4.5e-07 30.0 0.0 0.032 14.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII85519.1 - 6.3e-07 29.0 0.2 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KII85519.1 - 3.1e-06 26.6 0.6 0.021 14.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KII85519.1 - 1.2e-05 25.3 0.2 0.047 13.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KII85519.1 - 1.2e-05 25.9 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII85519.1 - 7.1e-05 23.1 0.4 0.48 10.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KII85519.1 - 7.8e-05 22.1 0.1 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 KII85519.1 - 0.0001 22.4 4.0 0.028 14.5 0.2 2.8 3 0 0 3 3 2 2 Dynamin family DUF815 PF05673.13 KII85519.1 - 0.00064 19.0 0.5 0.19 10.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 KII85519.1 - 0.001 19.2 1.4 0.55 10.3 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 KII85519.1 - 0.0029 17.6 0.1 0.69 9.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KII85519.1 - 0.0036 17.5 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KII85519.1 - 0.0061 16.3 1.4 2.4 7.9 0.1 2.5 2 1 0 2 2 2 2 AAA domain MobB PF03205.14 KII85519.1 - 0.0096 15.8 1.0 2.7 7.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 KII85519.1 - 0.0098 15.6 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KII85519.1 - 0.011 15.4 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KII85519.1 - 0.013 15.1 0.6 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KII85519.1 - 0.013 14.4 0.6 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 KII85519.1 - 0.017 15.6 0.0 3 8.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII85519.1 - 0.019 14.2 1.0 2.8 7.1 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.9 KII85519.1 - 0.042 13.6 0.4 10 5.9 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KII85519.1 - 0.052 12.5 0.6 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KII85519.1 - 0.057 13.0 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KII85519.1 - 0.057 14.0 0.1 20 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KII85519.1 - 0.082 12.6 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 KII85519.1 - 0.099 12.4 0.2 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KII85519.1 - 0.13 12.7 0.0 35 4.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_7 PF12775.7 KII85519.1 - 0.14 11.7 0.2 14 5.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KII85519.1 - 0.18 11.0 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain TsaE PF02367.17 KII85519.1 - 0.18 11.8 0.2 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KII85519.1 - 0.18 11.5 0.5 31 4.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Sec61_beta PF03911.16 KII85520.1 - 8.3e-18 64.1 0.5 1.1e-17 63.7 0.5 1.2 1 0 0 1 1 1 1 Sec61beta family MGC-24 PF05283.11 KII85520.1 - 0.18 12.3 0.1 0.24 11.8 0.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Synaptobrevin PF00957.21 KII85521.1 - 3e-30 103.9 0.2 4.5e-30 103.3 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KII85521.1 - 5.6e-18 64.8 0.0 1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.9 KII85521.1 - 0.024 14.7 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SET PF00856.28 KII85522.1 - 8.6e-11 42.5 0.0 1.8e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 SET domain DNA_pol_A_exo1 PF01612.20 KII85523.1 - 3.3e-10 39.9 0.0 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 2 3'-5' exonuclease Glyco_hydro_71 PF03659.14 KII85524.1 - 1e-115 386.6 12.3 1.1e-115 386.4 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4118 PF13493.6 KII85525.1 - 0.024 14.4 1.4 0.53 10.1 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) HTH_3 PF01381.22 KII85526.1 - 9.4e-09 35.2 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KII85526.1 - 1.1e-07 32.1 0.0 1.2e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KII85526.1 - 0.0015 18.3 0.1 0.0025 17.5 0.0 1.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_19 PF12844.7 KII85526.1 - 0.0029 17.6 0.0 0.0039 17.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KII85526.1 - 0.015 15.7 0.0 0.019 15.4 0.0 1.1 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 KII85526.1 - 0.053 13.3 0.4 0.083 12.7 0.1 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KII85526.1 - 0.074 12.7 0.3 0.11 12.1 0.1 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 YdaS_antitoxin PF15943.5 KII85526.1 - 0.095 12.6 0.1 3.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2774 PF11242.8 KII85526.1 - 0.14 12.4 0.1 2.1 8.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2774) DUF4993 PF16384.5 KII85527.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function zf-RING_2 PF13639.6 KII85528.1 - 7.4e-05 23.0 16.2 0.00014 22.1 16.2 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII85528.1 - 0.0032 17.3 14.9 0.0063 16.4 14.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KII85528.1 - 0.005 16.7 16.0 0.0087 15.9 16.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85528.1 - 0.0061 16.5 14.7 0.011 15.7 14.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Troponin PF00992.20 KII85528.1 - 0.0077 16.5 6.7 0.03 14.6 0.2 2.8 3 0 0 3 3 3 1 Troponin zf-RING_UBOX PF13445.6 KII85528.1 - 0.018 15.0 15.1 0.02 14.9 11.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger PI3K_P85_iSH2 PF16454.5 KII85528.1 - 0.023 14.3 3.9 0.037 13.6 3.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain zf-RING_4 PF14570.6 KII85528.1 - 0.052 13.3 11.4 0.1 12.4 11.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps54_N PF10475.9 KII85528.1 - 0.066 12.5 0.7 0.1 11.9 0.7 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex THOC7 PF05615.13 KII85528.1 - 0.086 13.1 7.7 0.16 12.2 7.7 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Filament PF00038.21 KII85528.1 - 0.1 12.2 6.2 0.14 11.7 6.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Mto2_bdg PF12808.7 KII85528.1 - 0.13 12.6 3.6 0.4 11.0 1.6 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region LRRFIP PF09738.9 KII85528.1 - 0.13 11.7 7.9 0.25 10.8 7.9 1.4 1 0 0 1 1 1 0 LRRFIP family zf-RING_10 PF16685.5 KII85528.1 - 0.18 12.0 8.7 0.34 11.1 8.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KII85528.1 - 0.25 11.5 15.0 0.48 10.6 15.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UPF0242 PF06785.11 KII85528.1 - 0.43 10.7 4.1 0.68 10.0 4.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_IE-1 PF05290.11 KII85528.1 - 0.46 10.4 11.0 0.044 13.7 5.8 1.9 2 1 1 3 3 2 0 Baculovirus immediate-early protein (IE-0) DivIC PF04977.15 KII85528.1 - 0.58 10.0 3.0 1 9.2 1.5 2.1 2 1 0 2 2 2 0 Septum formation initiator DUF4618 PF15397.6 KII85528.1 - 0.61 9.5 7.9 1.5 8.2 7.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 KII85528.1 - 0.69 10.3 2.9 1.1 9.7 1.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KII85528.1 - 1.5 9.5 4.2 1.3 9.7 1.8 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KII85528.1 - 2.5 8.5 7.3 2.9 8.3 4.4 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C4H2 PF10146.9 KII85528.1 - 5.8 7.2 24.8 0.057 13.7 13.4 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein zf-C3HC4_2 PF13923.6 KII85528.1 - 6.5 6.7 15.6 14 5.6 15.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Striatin PF08232.12 KII85528.1 - 7.5 7.1 10.8 21 5.7 10.8 2.0 1 1 0 1 1 1 0 Striatin family bZIP_2 PF07716.15 KII85528.1 - 8.2 6.6 10.9 1.2 9.3 4.2 2.6 2 1 0 2 2 2 0 Basic region leucine zipper Costars PF14705.6 KII85529.1 - 8.1e-24 83.6 0.0 9.1e-24 83.4 0.0 1.0 1 0 0 1 1 1 1 Costars p450 PF00067.22 KII85530.1 - 6.3e-73 246.1 0.0 7.7e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GLE1 PF07817.13 KII85531.1 - 5.5e-51 173.2 0.0 1.5e-50 171.8 0.0 1.7 1 1 1 2 2 2 1 GLE1-like protein GAGA_bind PF06217.12 KII85531.1 - 2 8.7 19.5 3.3 7.9 19.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Lactonase PF10282.9 KII85533.1 - 8.4e-39 133.8 0.0 9.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Sirohm_synth_M PF14824.6 KII85533.1 - 0.21 11.0 0.3 0.55 9.7 0.3 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central adh_short_C2 PF13561.6 KII85534.1 - 1.3e-58 198.3 4.7 1.5e-58 198.1 4.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII85534.1 - 3e-52 176.9 1.7 3e-52 176.9 1.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KII85534.1 - 5.9e-11 42.6 0.8 9.6e-11 41.9 0.8 1.4 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.6 KII85534.1 - 0.067 13.8 0.5 0.24 12.1 0.3 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain NAD_binding_6 PF08030.12 KII85536.1 - 3.6e-20 72.7 0.0 2.7e-18 66.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KII85536.1 - 8.7e-20 71.1 8.8 2.7e-19 69.5 8.8 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KII85536.1 - 1.5e-14 54.0 0.0 1.1e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KII85536.1 - 0.12 13.0 0.0 31 5.3 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Stealth_CR4 PF17103.5 KII85536.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Ferric_reduct PF01794.19 KII85537.1 - 4.1e-21 75.4 8.6 1.1e-20 74.0 8.6 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KII85537.1 - 5.7e-20 72.0 0.0 9.3e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII85537.1 - 2.9e-12 46.6 0.1 5.6e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KII85537.1 - 0.00049 20.7 0.0 0.27 11.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF393 PF04134.12 KII85537.1 - 1.2 10.5 3.1 2 9.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF393 Oxidored_FMN PF00724.20 KII85538.1 - 9e-98 327.7 0.0 1e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CAP59_mtransfer PF11735.8 KII85539.1 - 3.5e-66 223.3 0.0 4.5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Haem_degrading PF03928.14 KII85541.1 - 2.4e-18 66.3 0.0 3.3e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading GTF2I PF02946.14 KII85542.1 - 0.086 12.9 0.1 15 5.8 0.0 2.9 3 0 0 3 3 3 0 GTF2I-like repeat Haem_degrading PF03928.14 KII85543.1 - 3.4e-19 69.1 0.0 4.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading UQ_con PF00179.26 KII85544.1 - 7.3e-41 139.1 0.0 9.7e-41 138.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DTHCT PF08070.11 KII85544.1 - 0.023 15.4 1.3 0.057 14.1 1.3 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region Adeno_E1A PF02703.14 KII85544.1 - 0.06 12.9 4.2 0.094 12.3 4.2 1.2 1 0 0 1 1 1 0 Early E1A protein UEV PF05743.13 KII85544.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain Herpes_UL24 PF01646.16 KII85545.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Herpes virus proteins UL24 and UL76 OPT PF03169.15 KII85546.1 - 3.6e-181 603.9 57.7 4.1e-181 603.8 57.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.11 KII85546.1 - 0.26 11.5 10.1 0.31 11.2 6.8 3.0 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA ThiF PF00899.21 KII85547.1 - 8.4e-12 45.0 0.0 5e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 ThiF family ParA PF10609.9 KII85548.1 - 2.5e-78 262.9 0.0 3.1e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KII85548.1 - 1.4e-15 57.5 0.0 4.1e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KII85548.1 - 7.1e-10 39.1 0.3 6.6e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KII85548.1 - 7.3e-08 32.0 0.1 1.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KII85548.1 - 1.3e-05 24.6 1.1 0.0002 20.6 0.4 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KII85548.1 - 0.00052 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KII85548.1 - 0.0014 17.7 0.3 0.0021 17.1 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 KII85548.1 - 0.0026 17.2 0.1 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KII85548.1 - 0.0045 16.8 0.8 0.47 10.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 KII85548.1 - 0.0047 16.7 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 KII85548.1 - 0.022 14.1 0.0 0.047 13.0 0.1 1.5 2 0 0 2 2 2 0 VirC1 protein APS_kinase PF01583.20 KII85548.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 KII85548.1 - 0.16 11.4 0.3 0.27 10.7 0.3 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ IFT57 PF10498.9 KII85550.1 - 0.11 11.5 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 L_biotic_typeA PF04604.13 KII85550.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Type-A lantibiotic SLD5_C PF16922.5 KII85551.1 - 0.0022 18.1 0.1 0.0043 17.2 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KII85551.1 - 0.0077 16.7 0.2 0.015 15.8 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein LysM PF01476.20 KII85553.1 - 3.2e-10 39.9 0.1 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 2 LysM domain UCR_Fe-S_N PF10399.9 KII85553.1 - 0.076 12.4 1.7 0.14 11.5 1.7 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ski_Sno PF02437.17 KII85553.1 - 0.084 12.6 0.1 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 SKI/SNO/DAC family zf-C2H2_4 PF13894.6 KII85557.1 - 0.0062 17.3 2.5 0.088 13.7 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KII85557.1 - 0.34 11.5 1.9 1.2 9.8 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KII85558.1 - 0.036 14.5 8.0 0.24 11.9 0.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85558.1 - 0.39 11.7 8.4 0.44 11.5 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L14 PF00238.19 KII85559.1 - 1.8e-35 121.7 0.0 2.1e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 KII85560.1 - 6.8e-17 61.1 0.0 9.7e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KII85560.1 - 0.0027 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KII85560.1 - 0.0081 15.7 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII85560.1 - 0.041 14.0 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RL PF17797.1 KII85560.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 RL domain Aldo_ket_red PF00248.21 KII85561.1 - 1.6e-39 135.9 0.2 2.4e-38 132.0 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HSP20 PF00011.21 KII85562.1 - 4.8e-15 55.5 0.1 2.7e-08 33.9 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII85562.1 - 2.6e-10 39.7 0.1 1.9e-09 36.9 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KII85562.1 - 0.067 13.3 0.3 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 GvpH FKBP26_C PF18046.1 KII85562.1 - 0.16 12.1 0.1 12 6.0 0.0 2.1 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 KII85563.1 - 1.4e-15 57.3 0.1 2.4e-15 56.5 0.1 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII85563.1 - 6.6e-09 35.2 0.0 2e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 KII85563.1 - 0.012 15.6 0.0 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal GvpH PF05455.11 KII85563.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 GvpH Catalase PF00199.19 KII85564.1 - 1.4e-183 610.3 0.1 1.8e-183 610.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KII85564.1 - 2.1e-16 59.9 0.0 5.2e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Nrap_D4 PF17405.2 KII85565.1 - 8.1e-65 218.2 0.1 6.4e-63 212.0 0.0 2.3 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KII85565.1 - 3e-42 144.4 0.0 5.2e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 KII85565.1 - 2e-39 134.8 0.0 1.5e-37 128.7 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 KII85565.1 - 7.9e-39 133.0 0.0 1.6e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KII85565.1 - 1.1e-37 129.4 0.0 1.6e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KII85565.1 - 2e-34 118.7 0.0 3.7e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Zn_ribbon_17 PF17120.5 KII85566.1 - 1.8e-08 33.9 17.9 1.8e-08 33.9 17.9 2.5 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KII85566.1 - 0.0034 18.2 0.1 0.0034 18.2 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat RWD PF05773.22 KII85566.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain CMAS PF02353.20 KII85568.1 - 2.8e-67 226.9 0.2 3.5e-67 226.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII85568.1 - 3.2e-12 47.0 0.0 2.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII85568.1 - 1.4e-11 44.9 0.0 1.2e-10 41.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII85568.1 - 2.4e-09 37.2 0.0 4.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII85568.1 - 6e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KII85568.1 - 5.9e-05 22.7 0.0 0.00018 21.1 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 KII85568.1 - 0.00037 20.1 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KII85568.1 - 0.00039 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII85568.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KII85568.1 - 0.048 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KII85568.1 - 0.058 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) YIF1 PF03878.15 KII85569.1 - 4.3e-93 311.3 0.4 5.2e-93 311.0 0.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 KII85569.1 - 4.3e-06 26.6 1.2 7.4e-06 25.8 1.2 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1658 PF07871.11 KII85570.1 - 0.47 10.5 6.0 0.2 11.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) tRNA-synt_2 PF00152.20 KII85571.1 - 0.15 11.1 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Cu_amine_oxid PF01179.20 KII85572.1 - 3.4e-50 171.1 0.1 1.1e-22 80.6 0.0 3.4 2 2 1 3 3 3 3 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KII85572.1 - 0.0067 16.6 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hyd_65N_2 PF14498.6 KII85573.1 - 3.8e-38 131.7 2.2 1.9e-37 129.4 2.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Epimerase PF01370.21 KII85574.1 - 3.4e-18 66.0 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII85574.1 - 6.7e-11 42.2 0.3 2.1e-10 40.5 0.3 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII85574.1 - 7e-10 38.5 0.3 2.3e-08 33.5 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KII85574.1 - 8.6e-09 34.8 0.0 1.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII85574.1 - 1.6e-08 34.7 0.8 2.3e-08 34.2 0.8 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII85574.1 - 3.6e-05 23.5 1.3 5.6e-05 22.8 1.3 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII85574.1 - 5.2e-05 22.5 0.1 7.9e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KII85574.1 - 0.0013 18.6 1.6 0.0057 16.6 1.6 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KII85574.1 - 0.0048 16.4 0.3 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KII85574.1 - 0.11 11.6 0.2 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Sulfate_transp PF00916.20 KII85575.1 - 0.016 14.0 3.6 0.019 13.7 3.6 1.2 1 0 0 1 1 1 0 Sulfate permease family Glyco_hydro_16 PF00722.21 KII85577.1 - 6.4e-18 64.8 0.5 1.2e-17 63.9 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KII85578.1 - 2e-56 191.0 1.5 6.7e-56 189.3 1.5 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KII85578.1 - 3.2e-05 24.0 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KII85578.1 - 0.00039 20.3 0.0 0.0055 16.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KII85578.1 - 0.039 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Helicase_C PF00271.31 KII85582.1 - 2.7e-17 63.1 0.0 9e-17 61.4 0.0 1.9 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII85582.1 - 1.3e-14 54.4 0.0 2.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII85582.1 - 1.6e-09 38.0 0.0 2.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KII85582.1 - 0.0012 18.6 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII85582.1 - 0.023 15.0 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NDUFB11 PF17250.2 KII85586.1 - 0.016 15.8 0.0 0.031 14.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit SPX PF03105.19 KII85587.1 - 6.9e-40 138.1 0.1 1.8e-38 133.5 0.1 2.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KII85587.1 - 3.6e-07 29.9 9.0 5.4e-07 29.4 9.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85587.1 - 2.2e-06 27.4 10.7 3.4e-06 26.8 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII85587.1 - 5.1e-05 23.3 11.4 8.3e-05 22.7 11.4 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII85587.1 - 0.0001 22.5 11.0 0.00016 21.9 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII85587.1 - 0.00069 19.4 9.7 0.0011 18.7 9.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KII85587.1 - 0.0013 18.6 12.2 0.002 17.9 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85587.1 - 0.0013 18.7 10.6 0.0023 17.8 10.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII85587.1 - 0.0057 16.7 9.0 0.011 15.8 9.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KII85587.1 - 0.015 15.1 6.9 0.03 14.1 6.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KII85587.1 - 0.13 12.6 7.0 0.24 11.7 7.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KII85587.1 - 0.37 10.7 5.0 0.68 9.8 5.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mss4 PF04421.13 KII85588.1 - 6.7e-14 51.8 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.25 KII85588.1 - 7.1e-13 48.8 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII85588.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII85588.1 - 6.1e-07 29.8 0.0 1.8e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII85588.1 - 0.00059 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII85588.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_13 PF13880.6 KII85588.1 - 0.0091 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KII85588.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase F-box-like PF12937.7 KII85589.1 - 9.4e-09 35.0 3.1 1.8e-08 34.1 3.1 1.6 1 0 0 1 1 1 1 F-box-like Asp PF00026.23 KII85590.1 - 5.2e-52 177.2 13.7 1.5e-51 175.8 13.7 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85590.1 - 8.4e-08 32.7 11.4 1.1e-05 25.7 0.6 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KII85590.1 - 2.1e-05 25.0 0.9 0.038 14.5 0.1 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII85590.1 - 5.7e-05 23.7 5.9 0.031 14.9 0.8 2.9 3 0 0 3 3 3 2 Aspartyl protease RVP PF00077.20 KII85590.1 - 0.13 12.6 0.3 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Pkinase PF00069.25 KII85591.1 - 5.4e-72 242.3 0.0 6.9e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII85591.1 - 1.7e-34 119.3 0.0 2.3e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KII85591.1 - 2.5e-12 47.3 1.9 2.5e-12 47.3 1.9 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KII85591.1 - 1.7e-05 24.0 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KII85591.1 - 0.0019 17.5 0.0 0.0049 16.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KII85591.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KII85591.1 - 0.14 11.8 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KII85591.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KII85593.1 - 9.1e-11 41.5 2.6 9.1e-11 41.5 2.6 1.9 2 0 0 2 2 2 1 F-box-like Yuri_gagarin PF15934.5 KII85593.1 - 0.0068 16.3 0.2 0.0091 15.9 0.2 1.1 1 0 0 1 1 1 1 Yuri gagarin F-box PF00646.33 KII85593.1 - 0.64 10.0 4.9 12 5.9 0.6 3.2 3 0 0 3 3 3 0 F-box domain rRNA_proc-arch PF13234.6 KII85594.1 - 1.6e-88 297.1 0.0 2.6e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KII85594.1 - 5.6e-52 175.7 0.3 1.1e-51 174.7 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KII85594.1 - 9.4e-18 64.6 0.0 2.6e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII85594.1 - 3.9e-08 33.6 0.1 3.1e-07 30.7 0.1 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII85594.1 - 0.00037 20.6 0.0 0.00099 19.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KII85594.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KII85594.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glyco_hydro_18 PF00704.28 KII85595.1 - 1.5e-68 231.8 10.9 2.1e-68 231.4 10.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KII85595.1 - 0.19 12.4 13.1 0.073 13.7 7.4 3.0 2 0 0 2 2 2 0 Carbohydrate binding domain Asp PF00026.23 KII85597.1 - 4.9e-24 85.3 0.0 7e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85597.1 - 0.0078 16.5 0.9 1.7 8.9 0.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Gp58 PF07902.11 KII85597.1 - 0.21 9.9 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein F-box-like PF12937.7 KII85598.1 - 1.2e-05 25.1 0.2 3.8e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII85598.1 - 1.6e-05 24.6 0.2 5.5e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KII85598.1 - 0.077 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 F-box Ras PF00071.22 KII85599.1 - 4.3e-34 117.5 0.3 5.1e-34 117.2 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII85599.1 - 1.7e-25 89.5 0.3 4e-25 88.4 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII85599.1 - 8.3e-08 31.9 0.1 1.1e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII85599.1 - 5.4e-07 29.2 0.2 6.9e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KII85599.1 - 0.0095 15.1 0.5 0.14 11.3 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit DLIC PF05783.11 KII85599.1 - 0.0099 14.7 0.3 1.4 7.7 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 KII85599.1 - 0.015 14.8 0.0 1.9 7.9 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KII85599.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase CDH-cyt PF16010.5 KII85600.1 - 8.2e-55 185.3 0.2 8.2e-55 185.3 0.2 1.9 1 1 1 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KII85600.1 - 3.6e-17 62.7 0.0 8.6e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII85600.1 - 3.4e-16 60.1 0.0 7.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII85600.1 - 3.6e-05 23.0 0.0 0.00041 19.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KII85600.1 - 0.00014 21.4 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KII85600.1 - 0.00024 19.9 0.1 0.00036 19.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KII85600.1 - 0.00025 21.2 0.2 0.00081 19.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII85600.1 - 0.00056 19.2 0.2 0.00094 18.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII85600.1 - 0.00091 18.6 0.2 0.0016 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KII85600.1 - 0.0011 18.2 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KII85600.1 - 0.016 14.5 2.1 0.024 13.9 1.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII85600.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A vATP-synt_E PF01991.18 KII85601.1 - 8.3e-57 191.8 9.6 9.6e-57 191.6 9.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF883 PF05957.13 KII85601.1 - 4 8.1 9.1 1.1 9.9 2.7 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2461 PF09365.10 KII85602.1 - 3.9e-73 245.8 0.0 6.4e-73 245.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC27 PF09507.10 KII85602.1 - 8.8 5.6 20.6 11 5.2 20.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HTH_38 PF13936.6 KII85603.1 - 0.12 12.2 0.7 0.57 10.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Paf67 PF10255.9 KII85604.1 - 2e-167 557.3 0.0 2.5e-167 557.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KII85604.1 - 0.014 15.5 0.0 0.083 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KII85604.1 - 0.089 12.6 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PCRF PF03462.18 KII85605.1 - 1.9e-49 168.1 0.1 1e-48 165.8 0.0 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KII85605.1 - 1.4e-34 118.4 3.4 2.3e-34 117.8 3.4 1.3 1 0 0 1 1 1 1 RF-1 domain RSN1_7TM PF02714.15 KII85606.1 - 3e-79 266.2 30.7 4.8e-79 265.5 22.6 2.2 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KII85606.1 - 1.2e-36 125.8 3.4 5.2e-36 123.8 3.4 2.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KII85606.1 - 3.1e-33 115.5 0.0 4.5e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter EF-hand_6 PF13405.6 KII85608.1 - 2.2e-11 42.7 0.2 0.00017 21.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KII85608.1 - 2.5e-11 43.9 0.0 2.8e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KII85608.1 - 3.5e-10 38.7 0.1 0.00044 19.6 0.0 3.3 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KII85608.1 - 2e-06 28.0 0.0 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KII85608.1 - 1.8e-05 24.5 0.1 0.0015 18.3 0.1 3.0 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KII85608.1 - 0.084 12.4 0.2 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_11 PF08976.11 KII85608.1 - 0.094 13.6 0.0 0.39 11.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain SapB_1 PF05184.15 KII85608.1 - 0.13 12.3 0.0 2.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 DDE_Tnp_IS66_C PF13817.6 KII85608.1 - 0.21 11.8 0.2 0.8 10.0 0.1 1.9 2 0 0 2 2 2 0 IS66 C-terminal element UBX PF00789.20 KII85609.1 - 2.5e-06 27.6 0.0 5.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KII85609.1 - 0.00021 21.0 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Inhibitor_Mig-6 PF11555.8 KII85609.1 - 0.61 10.2 3.5 2.8 8.1 3.6 2.0 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 DUF4800 PF16057.5 KII85609.1 - 1.4 8.2 4.9 2.1 7.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) U79_P34 PF03064.16 KII85609.1 - 5.6 6.3 8.7 9.2 5.5 8.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FhuF PF06276.12 KII85610.1 - 0.055 13.9 0.0 0.084 13.3 0.0 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter CBM_20 PF00686.19 KII85613.1 - 5.8e-53 176.8 2.0 1.9e-25 88.6 0.2 2.6 2 0 0 2 2 2 2 Starch binding domain Alpha-amylase PF00128.24 KII85613.1 - 7.6e-12 45.4 0.0 1.3e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain ABC2_membrane_2 PF12679.7 KII85614.1 - 0.27 10.5 6.2 0.46 9.7 6.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 KII85614.1 - 0.55 9.9 15.0 0.095 12.4 11.2 1.6 1 1 1 2 2 2 0 Tetraspanin family Flavin_Reduct PF01613.18 KII85616.1 - 3.1e-20 72.8 0.0 4.3e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Cupin_5 PF06172.11 KII85617.1 - 4.3e-41 140.4 0.0 5.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Synaptobrevin PF00957.21 KII85618.1 - 7.4e-15 54.5 1.0 1.2e-14 53.9 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KII85618.1 - 8.3e-13 48.2 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain An_peroxidase PF03098.15 KII85619.1 - 8.9e-32 110.3 0.0 1.9e-22 79.6 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase NAD_binding_6 PF08030.12 KII85621.1 - 1.5e-18 67.4 0.0 2.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII85621.1 - 4.1e-14 52.6 0.0 1e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KII85621.1 - 0.0056 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ferric_reduct PF01794.19 KII85621.1 - 0.015 15.4 0.5 0.028 14.5 0.5 1.5 1 0 0 1 1 1 0 Ferric reductase like transmembrane component Nup96 PF12110.8 KII85622.1 - 0.04 13.0 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 FHA PF00498.26 KII85624.1 - 4.2e-14 52.7 0.0 7.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KII85624.1 - 1.9e-11 43.5 8.6 3.2e-11 42.8 8.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KII85624.1 - 1.3e-08 35.0 10.7 2.4e-08 34.2 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII85624.1 - 7.1e-05 22.6 10.4 0.00011 21.9 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85624.1 - 0.00011 22.0 10.9 0.00018 21.2 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KII85624.1 - 0.00011 22.4 6.9 0.00021 21.5 6.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII85624.1 - 0.0005 20.1 2.2 0.0009 19.3 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KII85624.1 - 0.0034 17.3 9.0 0.0055 16.6 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.29 KII85624.1 - 0.035 14.0 5.2 0.061 13.2 5.2 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KII85624.1 - 0.065 13.1 6.8 0.11 12.3 6.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KII85624.1 - 0.25 11.0 5.4 0.41 10.3 5.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KII85624.1 - 0.7 10.0 12.1 0.26 11.3 9.6 1.6 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KII85624.1 - 1.3 9.0 8.4 2.6 8.0 8.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_P_p30 PF01876.16 KII85625.1 - 6.5e-35 120.6 0.0 7.6e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 E1-E2_ATPase PF00122.20 KII85628.1 - 1.9e-23 82.9 0.1 4.2e-23 81.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KII85628.1 - 6.1e-14 52.8 0.0 1.4e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KII85628.1 - 9.2e-06 25.7 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KII85628.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KII85628.1 - 0.057 12.9 0.1 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Glucos_trans_II PF14264.6 KII85628.1 - 0.12 11.8 6.8 0.2 11.0 0.2 2.8 3 0 0 3 3 3 0 Glucosyl transferase GtrII Cation_ATPase_N PF00690.26 KII85628.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus HTH_AsnC-type PF13404.6 KII85631.1 - 0.029 14.2 1.2 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ADC PF06314.11 KII85632.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) F-box-like PF12937.7 KII85633.1 - 6.8e-09 35.5 0.5 1.6e-08 34.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_L1 PF00687.21 KII85634.1 - 3.1e-46 157.7 2.3 3.6e-46 157.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PhoLip_ATPase_C PF16212.5 KII85635.1 - 2.4e-73 247.0 29.3 2.4e-73 247.0 29.3 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KII85635.1 - 1.6e-22 79.0 0.2 5e-22 77.4 0.2 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KII85635.1 - 2.9e-12 46.5 0.0 5.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KII85635.1 - 5.2e-12 46.5 0.1 2.7e-06 27.8 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KII85635.1 - 6e-06 25.9 0.0 6e-06 25.9 0.0 3.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KII85635.1 - 0.0049 16.6 0.1 0.046 13.4 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KII85637.1 - 1.7e-20 73.2 0.0 3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85637.1 - 2e-09 37.4 12.0 4.6e-09 36.2 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 KII85638.1 - 3.3e-38 129.3 0.0 1.5e-13 50.3 0.0 7.0 7 0 0 7 7 7 5 Ubiquitin family Rad60-SLD PF11976.8 KII85638.1 - 5.7e-10 38.9 0.0 0.0005 19.9 0.0 4.5 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KII85638.1 - 5.2e-08 33.5 0.1 0.1 13.3 0.0 5.1 4 1 0 4 4 4 2 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 KII85638.1 - 3.5e-05 24.2 1.3 3.7 8.1 0.0 6.2 5 2 0 5 5 5 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KII85638.1 - 0.00014 21.8 0.2 63 3.7 0.0 6.6 6 2 2 8 8 8 0 Ubiquitin-like domain DWNN PF08783.11 KII85638.1 - 0.0091 16.3 0.1 11 6.4 0.0 3.3 4 0 0 4 4 4 2 DWNN domain Solute_trans_a PF03619.16 KII85639.1 - 2.8e-91 305.7 10.4 3.4e-91 305.4 10.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.16 KII85640.1 - 4.9e-40 137.5 34.3 4.9e-40 137.5 34.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII85640.1 - 5.2e-16 58.6 6.9 5.2e-16 58.6 6.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KII85640.1 - 0.00048 19.5 5.2 0.00048 19.5 5.2 3.4 3 1 1 4 4 4 2 Uncharacterised MFS-type transporter YbfB Aldo_ket_red PF00248.21 KII85641.1 - 1.9e-63 214.4 0.0 2.2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family U6-snRNA_bdg PF10596.9 KII85641.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 CopB PF05275.11 KII85641.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Redoxin PF08534.10 KII85642.1 - 2.8e-35 121.2 0.0 3.2e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KII85642.1 - 3.1e-09 36.8 0.0 3.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glyco_hydro_76 PF03663.14 KII85643.1 - 7.1e-30 104.7 22.4 3e-27 96.1 6.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 YtfJ_HI0045 PF09695.10 KII85643.1 - 0.12 12.0 1.1 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) Ndc1_Nup PF09531.10 KII85644.1 - 9.2e-79 265.7 0.1 1.2e-78 265.4 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup TRAM_LAG1_CLN8 PF03798.16 KII85645.1 - 0.00072 19.3 21.1 0.0015 18.3 21.1 1.6 1 1 0 1 1 1 1 TLC domain OTT_1508_deam PF14441.6 KII85646.1 - 1.3e-05 25.1 1.0 2.7e-05 24.1 1.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase OTT_1508_deam PF14441.6 KII85647.1 - 1.6e-05 24.8 0.6 1.6e-05 24.8 0.6 2.0 2 0 0 2 2 2 1 OTT_1508-like deaminase Asp PF00026.23 KII85648.1 - 1.4e-35 123.2 0.0 7.3e-18 65.0 1.7 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KII85648.1 - 0.00051 20.6 2.3 0.13 12.9 0.3 3.6 3 1 0 3 3 3 1 Aspartyl protease TAXi_N PF14543.6 KII85648.1 - 0.0034 17.6 1.5 0.06 13.6 1.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KII85648.1 - 0.019 15.5 0.1 0.56 10.8 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Mito_carr PF00153.27 KII85649.1 - 7.8e-54 179.6 0.4 5.9e-17 61.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Pex19 PF04614.12 KII85650.1 - 1.1e-59 202.2 0.1 4.5e-59 200.2 0.0 1.8 2 0 0 2 2 2 1 Pex19 protein family GET2 PF08690.10 KII85650.1 - 0.85 9.2 7.0 0.69 9.5 0.1 2.3 2 1 0 2 2 2 0 GET complex subunit GET2 CAP_N PF01213.19 KII85650.1 - 3.9 6.9 11.2 0.58 9.6 3.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NAD_binding_4 PF07993.12 KII85651.1 - 5e-31 107.8 0.0 8.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII85651.1 - 1.4e-17 63.4 0.0 3.5e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII85651.1 - 3.5e-09 36.5 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII85651.1 - 0.00019 21.4 0.0 0.0012 18.7 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding PP-binding PF00550.25 KII85651.1 - 0.029 14.7 0.2 0.27 11.6 0.2 2.6 1 1 0 1 1 1 0 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KII85651.1 - 0.093 12.1 0.0 0.38 10.1 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase U62_UL91 PF17442.2 KII85651.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins Abhydrolase_6 PF12697.7 KII85654.1 - 1.9e-14 54.8 5.7 1.9e-14 54.8 5.7 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII85654.1 - 0.00072 18.9 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII85654.1 - 0.041 13.5 0.1 0.28 10.8 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Methyltransf_11 PF08241.12 KII85655.1 - 3.7e-19 69.2 0.0 5.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII85655.1 - 2.4e-18 66.6 0.1 5.1e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII85655.1 - 1.3e-12 48.3 0.0 2.1e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII85655.1 - 3.1e-10 40.0 0.0 5.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII85655.1 - 3.8e-06 26.8 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII85655.1 - 7.2e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KII85655.1 - 0.0046 16.5 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KII85655.1 - 0.12 12.1 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Fer2_3 PF13085.6 KII85656.1 - 7e-34 116.1 0.0 1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KII85656.1 - 5.7e-10 39.6 7.0 5.7e-10 39.6 7.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KII85656.1 - 3.7e-07 30.2 3.9 3.7e-07 30.2 3.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KII85656.1 - 7e-07 29.6 7.7 7e-07 29.6 7.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KII85656.1 - 0.0012 19.4 4.9 0.0012 19.4 4.9 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KII85656.1 - 0.0023 17.8 2.9 0.0027 17.6 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NMO PF03060.15 KII85657.1 - 1.8e-55 188.6 1.7 8.8e-55 186.4 1.7 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KII85657.1 - 7.8e-10 38.3 0.6 0.00046 19.3 0.4 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KII85657.1 - 0.045 12.8 0.6 0.1 11.6 0.6 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NanE PF04131.14 KII85657.1 - 0.05 12.8 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Epimerase PF01370.21 KII85658.1 - 1.9e-21 76.6 0.0 6.4e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII85658.1 - 1.7e-13 50.2 0.0 8.1e-13 48.0 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII85658.1 - 9.8e-12 45.1 0.8 1.4e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII85658.1 - 4.3e-10 39.5 0.2 9.8e-10 38.3 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII85658.1 - 4.7e-08 32.5 0.0 7.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KII85658.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KII85658.1 - 0.0042 16.7 0.1 0.011 15.3 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KII85658.1 - 0.018 14.5 0.5 0.11 11.9 0.1 2.3 1 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 KII85659.1 - 7.1e-22 78.0 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII85659.1 - 2.2e-12 46.6 0.0 5.6e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KII85659.1 - 2.3e-09 37.1 0.2 4.1e-09 36.3 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII85659.1 - 6.1e-09 36.0 0.2 1.8e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII85659.1 - 4.2e-07 29.4 0.0 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KII85659.1 - 0.0012 18.5 0.1 0.0041 16.7 0.2 1.8 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII85659.1 - 0.19 10.8 0.2 0.38 9.8 0.2 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KII85661.1 - 2.5e-09 36.9 0.1 3.6e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 F-box-like TetR PF13972.6 KII85661.1 - 0.14 11.9 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor Phytase-like PF13449.6 KII85662.1 - 1.8e-33 116.7 0.0 2.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 KII85662.1 - 0.059 12.6 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 SdiA-regulated Phytase-like PF13449.6 KII85663.1 - 8.9e-34 117.7 1.1 1.2e-33 117.3 1.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Abhydrolase_2 PF02230.16 KII85664.1 - 0.00045 20.1 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KII85664.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KII85664.1 - 0.0017 17.1 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KII85664.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII85664.1 - 0.028 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.12 KII85665.1 - 0.00037 19.3 0.0 0.063 11.9 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KII85665.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KII85665.1 - 0.00095 18.7 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KII85665.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KII85665.1 - 0.035 13.8 0.1 0.1 12.2 0.1 1.8 1 1 0 1 1 1 0 Putative esterase AMP-binding PF00501.28 KII85670.1 - 3.4e-51 174.2 0.0 4.9e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KII85670.1 - 2.5e-15 55.5 2.2 0.00022 20.8 0.0 7.5 7 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KII85670.1 - 1.3e-09 38.3 0.1 4.9e-09 36.4 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 KII85670.1 - 0.00014 21.6 6.4 4.8 7.0 0.2 5.3 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase zf-C3HC4 PF00097.25 KII85670.1 - 0.005 16.7 1.8 0.0089 15.9 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII85670.1 - 0.015 15.2 1.6 0.028 14.3 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85670.1 - 0.028 14.3 1.7 0.054 13.4 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMP-binding_C PF13193.6 KII85670.1 - 0.046 14.7 0.1 0.6 11.1 0.1 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain zf-RING_UBOX PF13445.6 KII85670.1 - 0.2 11.7 4.8 0.47 10.5 4.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KII85670.1 - 0.29 11.3 3.7 0.57 10.4 3.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KII85670.1 - 0.37 10.7 1.7 0.67 9.9 1.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KII85670.1 - 0.69 9.9 3.0 2.2 8.3 3.1 1.8 1 1 1 2 2 2 0 zinc-RING finger domain F-box-like PF12937.7 KII85672.1 - 9.4e-10 38.2 2.3 1.9e-09 37.2 2.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII85672.1 - 0.074 12.9 3.2 7.5 6.6 0.2 2.6 2 0 0 2 2 2 0 F-box domain Pil1 PF13805.6 KII85674.1 - 1.8e-18 67.0 0.4 2.6e-18 66.5 0.4 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3510 PF12022.8 KII85674.1 - 0.021 15.2 0.2 0.042 14.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DHR10 PF18595.1 KII85674.1 - 0.6 10.2 4.7 0.083 12.9 0.4 1.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain RNA_capsid PF03035.14 KII85675.1 - 8.9 6.2 10.6 20 5.1 10.6 1.6 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein GIT_SHD PF08518.11 KII85676.1 - 1.4e-15 56.6 0.9 4.6e-11 42.1 0.2 2.3 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Beta-lactamase PF00144.24 KII85679.1 - 3.8e-43 148.0 0.0 5.8e-43 147.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase FlgD_ig PF13860.6 KII85680.1 - 0.024 14.5 1.6 0.052 13.4 0.3 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain VIR_N PF15912.5 KII85680.1 - 0.15 11.7 2.2 0.31 10.6 2.2 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal adh_short_C2 PF13561.6 KII85681.1 - 6.2e-31 107.7 0.5 8.6e-31 107.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII85681.1 - 1.3e-20 73.7 0.3 1.6e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase AdoHcyase_NAD PF00670.21 KII85681.1 - 0.0033 17.5 0.9 0.027 14.6 0.9 2.1 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.19 KII85681.1 - 0.0045 16.3 0.1 0.0074 15.6 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 KII85681.1 - 0.024 14.5 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 KII85681.1 - 0.13 11.7 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KII85682.1 - 3.3e-31 108.6 0.0 4.1e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII85682.1 - 2.1e-23 82.8 0.0 2.7e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KII85682.1 - 0.0025 17.2 0.1 0.0042 16.4 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 KII85682.1 - 0.0064 16.4 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KII85682.1 - 0.037 14.1 0.6 0.077 13.1 0.5 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.19 KII85682.1 - 0.058 12.1 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.21 KII85682.1 - 0.13 11.7 0.2 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KII85682.1 - 0.21 11.4 1.1 0.38 10.5 0.9 1.6 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.6 KII85683.1 - 1.8e-32 112.8 0.0 2.4e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII85683.1 - 4.4e-17 62.2 0.0 5.7e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase PTR2 PF00854.21 KII85684.1 - 4.1e-79 266.3 6.5 5.3e-79 265.9 6.5 1.1 1 0 0 1 1 1 1 POT family eIF-1a PF01176.19 KII85684.1 - 0.088 12.6 0.0 18 5.2 0.0 3.4 4 0 0 4 4 4 0 Translation initiation factor 1A / IF-1 AhpC-TSA PF00578.21 KII85686.1 - 1.3e-27 96.1 0.0 1.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII85686.1 - 8.8e-20 70.9 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KII85686.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme HMG14_17 PF01101.18 KII85686.1 - 0.021 15.8 13.2 0.048 14.6 13.2 1.6 1 0 0 1 1 1 0 HMG14 and HMG17 LRR_6 PF13516.6 KII85687.1 - 7e-16 56.9 24.1 0.018 15.0 0.1 9.9 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.7 KII85687.1 - 4e-08 33.4 17.8 0.027 14.9 1.1 6.4 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII85687.1 - 6.2e-06 26.0 9.2 6.6 7.7 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 KII85687.1 - 0.00038 20.1 22.8 1.7 8.5 3.7 6.9 4 1 0 5 5 5 3 Leucine rich repeat GAT PF03127.14 KII85687.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 GAT domain GST_N_3 PF13417.6 KII85690.1 - 1e-10 41.9 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII85690.1 - 3.6e-06 27.2 0.2 6.4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII85690.1 - 0.0039 17.2 1.3 0.02 14.9 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII85690.1 - 0.0073 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII85690.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KII85691.1 - 1.2e-06 28.3 0.0 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII85691.1 - 0.0013 18.5 0.1 0.0047 16.8 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 KII85691.1 - 0.036 13.8 0.6 0.29 10.9 0.1 2.2 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 KII85691.1 - 0.071 13.6 0.3 0.95 10.0 0.3 2.4 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) TAL_FSA PF00923.19 KII85692.1 - 2.7e-94 315.8 0.0 3.1e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase adh_short_C2 PF13561.6 KII85693.1 - 3.2e-31 108.7 0.1 4.2e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII85693.1 - 2.5e-18 66.2 0.1 3.2e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KII85693.1 - 0.0067 15.8 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KII85693.1 - 0.039 14.0 1.0 0.16 12.0 1.0 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1761 PF08570.10 KII85694.1 - 7.9 6.8 12.1 0.5 10.6 0.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF2939 PF11159.8 KII85695.1 - 0.14 12.6 0.1 2.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Peptidase_M14 PF00246.24 KII85696.1 - 4e-64 217.2 0.0 5.4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ATG13 PF10033.9 KII85697.1 - 2.8e-51 174.5 0.0 3.9e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Asp PF00026.23 KII85699.1 - 5.7e-77 259.2 11.2 6.8e-77 259.0 11.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85699.1 - 2.6e-09 37.6 4.4 0.00023 21.5 0.2 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII85699.1 - 8.6e-07 28.9 0.0 3e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF1918 PF08940.11 KII85699.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Asp PF00026.23 KII85700.1 - 1.4e-44 152.8 3.7 1e-43 150.0 3.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85700.1 - 3.4e-05 24.1 4.5 0.036 14.3 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII85700.1 - 0.012 16.2 2.6 0.45 11.2 0.9 2.6 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KII85700.1 - 0.015 15.1 0.8 0.33 10.7 0.3 2.7 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Peptidase_M4_C PF02868.15 KII85700.1 - 0.04 13.8 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Asp PF00026.23 KII85701.1 - 3.8e-42 144.8 12.1 9.9e-42 143.5 12.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII85701.1 - 1.7e-08 34.9 5.8 9.9e-05 22.6 0.2 3.3 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII85701.1 - 0.0028 18.3 6.9 0.031 14.9 1.5 3.2 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KII85701.1 - 0.14 12.8 4.6 1.6 9.3 0.3 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease F-box-like PF12937.7 KII85703.1 - 0.021 14.7 0.8 0.055 13.4 0.5 1.8 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 KII85703.1 - 0.031 14.2 0.1 0.073 13.0 0.0 1.6 2 0 0 2 2 2 0 F-box Peptidase_S9 PF00326.21 KII85704.1 - 0.00088 18.8 0.3 0.0057 16.1 0.3 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KII85704.1 - 0.0011 18.5 0.1 0.0028 17.2 0.1 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KII85704.1 - 0.0013 18.6 0.5 0.0034 17.2 0.5 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF4995 PF16386.5 KII85704.1 - 0.021 14.8 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function AXE1 PF05448.12 KII85704.1 - 0.052 12.2 0.0 0.11 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KII85704.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 KII85704.1 - 0.26 10.1 1.4 2.8 6.7 0.1 2.5 3 1 1 4 4 4 0 Carboxylesterase family Glyco_hydro_79n PF03662.14 KII85705.1 - 0.22 10.4 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain JSRP PF15312.6 KII85705.1 - 3.5 7.6 14.6 18 5.3 0.1 5.1 2 2 3 5 5 5 0 Junctional sarcoplasmic reticulum protein Esterase_phd PF10503.9 KII85706.1 - 9e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KII85706.1 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KII85706.1 - 0.00027 20.5 0.0 0.015 14.7 0.1 2.3 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KII85706.1 - 0.001 17.8 0.1 0.5 9.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 KII85706.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family F-box_4 PF15966.5 KII85707.1 - 0.00028 20.7 0.1 0.00052 19.9 0.1 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KII85707.1 - 0.0033 17.3 0.1 0.0078 16.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KII85708.1 - 9e-29 100.5 22.6 3.4e-28 98.6 23.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4405 PF14358.6 KII85708.1 - 8.5 7.0 10.9 0.85 10.2 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) zf-C3HC4_3 PF13920.6 KII85713.1 - 3.1e-09 36.6 2.1 3.1e-09 36.6 2.1 3.7 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.12 KII85713.1 - 0.0041 17.2 3.8 0.84 9.7 1.7 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) Prok-RING_4 PF14447.6 KII85713.1 - 0.0059 16.5 4.4 0.0059 16.5 4.4 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C2H2 PF00096.26 KII85715.1 - 0.0011 19.3 0.2 0.0043 17.4 0.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII85715.1 - 0.0031 18.2 0.6 0.015 16.1 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger Ogr_Delta PF04606.12 KII85715.1 - 0.016 15.2 0.3 0.049 13.6 0.3 1.9 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-Di19 PF05605.12 KII85715.1 - 0.08 13.2 0.1 0.62 10.4 0.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KII85715.1 - 0.11 12.3 0.7 0.25 11.2 0.7 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-BED PF02892.15 KII85715.1 - 0.22 11.6 0.7 0.65 10.1 0.7 1.9 1 0 0 1 1 1 0 BED zinc finger FOXP-CC PF16159.5 KII85715.1 - 7.3 7.3 5.0 4.4 8.0 0.1 2.8 2 2 1 3 3 3 0 FOXP coiled-coil domain AMP-binding PF00501.28 KII85716.1 - 2e-52 178.2 0.0 2.9e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 KII85716.1 - 2.8e-13 49.0 6.7 0.0025 17.5 0.1 7.0 7 1 0 7 7 7 4 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 KII85716.1 - 1.7e-10 41.1 0.7 5.5e-10 39.5 0.7 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KII85716.1 - 0.0022 18.9 0.2 0.4 11.7 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 KII85716.1 - 0.0039 16.9 3.0 7.7 6.4 0.2 5.2 4 2 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Aldo_ket_red PF00248.21 KII85717.1 - 2.3e-48 164.9 0.0 2.7e-46 158.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peroxin-3 PF04882.12 KII85718.1 - 4.3e-132 441.5 0.0 5.1e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF5637 PF18687.1 KII85720.1 - 0.00075 19.4 7.6 0.0018 18.2 7.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5637) Toxin_35 PF10530.9 KII85720.1 - 0.011 15.7 1.8 0.011 15.7 1.8 1.7 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Toxin_30 PF08117.11 KII85720.1 - 0.013 15.7 3.1 0.013 15.7 3.1 2.1 2 0 0 2 2 2 0 Ptu family Kdo PF06293.14 KII85721.1 - 6.5e-06 25.7 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII85721.1 - 0.00015 21.7 2.7 0.00046 20.2 2.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII85721.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KII85721.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KII85721.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF3602 PF12223.8 KII85723.1 - 2.6e-15 56.8 23.7 5.8e-07 30.0 8.0 4.6 1 1 1 4 4 4 3 Protein of unknown function (DUF3602) RAP1 PF07218.11 KII85723.1 - 0.3 9.3 0.9 0.6 8.3 0.9 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDE_1 PF03184.19 KII85726.1 - 2.5e-25 89.1 0.0 4.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KII85726.1 - 0.00045 20.2 0.1 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KII85726.1 - 0.012 15.4 0.7 2.1 8.1 0.0 3.1 2 1 1 3 3 3 0 DDE superfamily endonuclease Glyco_hydro_125 PF06824.11 KII85727.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) ZapB PF06005.12 KII85729.1 - 0.031 14.7 6.1 0.081 13.4 6.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF5500 PF17604.2 KII85733.1 - 0.066 13.3 0.1 0.088 12.9 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5500) SIL1 PF16782.5 KII85734.1 - 0.18 11.0 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Epimerase PF01370.21 KII85735.1 - 3.1e-20 72.7 0.0 5.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII85735.1 - 4e-12 46.2 0.0 5.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII85735.1 - 1.1e-11 44.4 0.3 7.6e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KII85735.1 - 4.4e-11 42.3 0.1 7.2e-11 41.6 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII85735.1 - 1.4e-08 34.9 0.3 2.1e-08 34.3 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KII85735.1 - 6e-05 22.3 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KII85735.1 - 0.00045 19.7 0.4 0.00093 18.7 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KII85735.1 - 0.003 17.2 0.4 0.0043 16.7 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KII85735.1 - 0.0073 16.2 1.1 0.024 14.6 1.1 1.8 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KII85735.1 - 0.079 12.0 0.2 0.2 10.8 0.2 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 KII85735.1 - 0.079 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Reprolysin_4 PF13583.6 KII85735.1 - 0.092 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_S28 PF05577.12 KII85736.1 - 3.3e-52 177.8 0.7 1e-51 176.1 0.7 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 SKN1 PF03935.15 KII85737.1 - 7.6e-185 615.1 5.5 8.4e-185 614.9 5.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box PF00646.33 KII85738.1 - 0.00058 19.7 0.0 0.0018 18.1 0.0 1.9 1 0 0 1 1 1 1 F-box domain MRI PF15325.6 KII85738.1 - 0.47 11.6 0.0 0.47 11.6 0.0 2.7 3 0 0 3 3 3 0 Modulator of retrovirus infection RIC3 PF15361.6 KII85739.1 - 0.046 14.1 0.0 0.053 13.9 0.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 UAA PF08449.11 KII85740.1 - 9.8e-75 251.6 10.2 1.1e-74 251.4 10.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KII85740.1 - 5.8e-06 26.5 30.0 0.0044 17.2 12.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KII85740.1 - 9.3e-06 25.0 4.2 1.2e-05 24.6 4.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KII85740.1 - 1.4e-05 24.2 0.6 2.5e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 KII85740.1 - 0.00027 20.3 9.2 0.001 18.4 0.7 2.3 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport Nup35_RRM PF05172.13 KII85741.1 - 1.2e-06 28.4 0.0 1.1e-05 25.3 0.0 2.4 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KII85741.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-ZPR1 PF03367.13 KII85742.1 - 2.1e-109 362.5 0.1 1.3e-53 181.1 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KII85742.1 - 0.0029 17.6 0.7 2.7 8.0 0.2 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KII85742.1 - 0.023 14.7 7.1 0.092 12.8 0.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.19 KII85742.1 - 0.057 13.8 1.5 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 DnaJ central domain Zn-ribbon_8 PF09723.10 KII85742.1 - 0.096 12.8 4.2 3.3 7.9 0.0 3.6 3 1 0 3 3 3 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 KII85742.1 - 0.11 12.5 0.8 15 5.7 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons DUF2688 PF10892.8 KII85742.1 - 0.16 11.5 5.6 0.76 9.3 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) OrfB_Zn_ribbon PF07282.11 KII85742.1 - 0.66 9.9 2.7 24 4.9 0.0 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Peptidase_C12 PF01088.21 KII85743.1 - 4.2e-56 190.0 0.0 5.3e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PAAR_motif PF05488.13 KII85746.1 - 0.013 15.7 0.8 0.48 10.6 0.1 2.1 2 0 0 2 2 2 0 PAAR motif RTC4 PF14474.6 KII85748.1 - 1.2e-22 80.4 0.0 1.3e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain ABC_membrane PF00664.23 KII85750.1 - 1.5e-63 215.0 26.2 1e-31 110.6 7.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII85750.1 - 1.4e-54 184.3 0.1 1.3e-30 106.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 KII85750.1 - 2.7e-05 24.2 0.9 0.24 11.5 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KII85750.1 - 3.3e-05 23.8 1.6 4.5 7.0 0.0 4.0 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KII85750.1 - 0.00016 22.1 0.0 0.09 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KII85750.1 - 0.00023 21.1 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KII85750.1 - 0.0018 18.0 1.0 0.53 10.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KII85750.1 - 0.0047 17.4 0.7 2.3 8.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KII85750.1 - 0.0055 15.7 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 KII85750.1 - 0.008 15.6 0.1 5.2 6.4 0.2 3.5 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KII85750.1 - 0.019 14.1 0.1 0.24 10.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KII85750.1 - 0.024 13.9 0.1 2.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF4574 PF15141.6 KII85750.1 - 0.025 14.5 0.0 0.083 12.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Dynamin_N PF00350.23 KII85750.1 - 0.029 14.4 1.9 5.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 KII85750.1 - 0.046 12.9 0.8 0.66 9.1 0.2 2.8 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KII85750.1 - 0.089 12.4 1.4 0.97 9.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KII85750.1 - 0.1 12.3 2.2 1.4 8.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KII85750.1 - 0.11 12.8 0.7 15 5.8 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 KII85750.1 - 0.62 10.1 4.6 5.1 7.1 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain SAD_SRA PF02182.17 KII85751.1 - 1.5e-49 167.7 0.7 1.9e-49 167.4 0.7 1.0 1 0 0 1 1 1 1 SAD/SRA domain DUF4839 PF16127.5 KII85751.1 - 0.17 12.0 0.1 0.31 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) SAE2 PF08573.10 KII85752.1 - 1.1e-22 81.3 1.1 1.1e-22 81.3 1.1 3.1 3 1 0 3 3 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Fungal_TACC PF12709.7 KII85752.1 - 0.0076 16.7 0.7 6.8 7.2 0.0 2.8 2 0 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins SOGA PF11365.8 KII85752.1 - 0.037 15.1 3.0 0.28 12.3 3.0 2.5 1 1 0 1 1 1 0 Protein SOGA DUF4372 PF14294.6 KII85752.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) FlaC_arch PF05377.11 KII85752.1 - 0.29 11.5 1.2 6.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KII85752.1 - 1.1 9.4 9.4 12 6.1 0.0 4.0 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 KII85752.1 - 2.4 8.4 11.4 1.6 9.0 0.9 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fez1 PF06818.15 KII85752.1 - 2.4 8.6 14.3 0.07 13.6 7.1 2.1 3 0 0 3 3 3 0 Fez1 KASH_CCD PF14662.6 KII85752.1 - 4.7 7.0 10.0 5.5 6.8 2.7 2.8 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH HAP1_N PF04849.13 KII85752.1 - 8.5 5.5 13.8 5.8 6.0 0.7 3.0 2 1 0 2 2 2 0 HAP1 N-terminal conserved region GAS PF13851.6 KII85752.1 - 9.6 5.5 11.9 0.41 10.0 1.2 3.2 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MS_channel PF00924.18 KII85753.1 - 2.1e-15 56.8 0.8 3.3e-15 56.2 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KII85753.1 - 5.4e-06 25.6 0.6 1.2e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KII85753.1 - 5.5e-05 22.8 0.0 0.00019 21.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KII85753.1 - 0.00047 20.5 0.6 0.0014 19.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KII85753.1 - 0.00076 18.9 0.1 0.0025 17.2 0.1 1.9 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.6 KII85753.1 - 0.0028 18.0 1.0 0.0028 18.0 1.0 2.7 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2207 PF09972.9 KII85753.1 - 0.01 14.7 0.0 0.072 11.8 0.1 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) MMPL PF03176.15 KII85753.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 MMPL family MutS_III PF05192.18 KII85753.1 - 0.11 12.7 0.5 0.86 9.8 1.8 1.7 1 1 0 1 1 1 0 MutS domain III DNA_ligase_A_M PF01068.21 KII85754.1 - 3.4e-23 82.4 0.0 6.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KII85754.1 - 3.5e-18 66.5 0.0 6.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KII85754.1 - 0.00035 20.9 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Rcd1 PF04078.13 KII85755.1 - 1.6e-124 414.4 2.7 1.9e-124 414.1 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.13 KII85756.1 - 5.8e-54 183.1 1.0 3.9e-33 114.8 0.5 2.2 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like HNH_2 PF13391.6 KII85756.1 - 0.012 15.7 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease FA_hydroxylase PF04116.13 KII85759.1 - 2.7e-22 79.6 7.0 2.7e-22 79.6 7.0 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily BUD22 PF09073.10 KII85760.1 - 0.018 14.4 12.5 0.022 14.1 12.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 KII85760.1 - 0.043 13.2 11.8 0.053 12.9 11.8 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 KII85760.1 - 0.056 12.0 8.5 0.073 11.7 8.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KII85760.1 - 0.2 9.9 8.1 0.24 9.6 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KII85760.1 - 0.28 9.4 10.0 0.32 9.1 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase_fungal PF17667.1 KII85762.1 - 1.3e-31 109.8 0.1 1.4e-31 109.7 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII85762.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KII85762.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_L28e PF01778.17 KII85764.1 - 1.9e-39 134.9 2.6 1.9e-39 134.9 2.6 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KII85764.1 - 3.4e-24 85.3 3.3 7.1e-24 84.3 3.3 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.15 KII85764.1 - 0.031 13.8 2.8 0.042 13.4 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1640 PF07798.11 KII85765.1 - 4.2e-61 206.0 11.1 4.9e-61 205.8 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) KIAA1430 PF13879.6 KII85765.1 - 0.055 14.2 5.3 0.1 13.4 5.3 1.4 1 0 0 1 1 1 0 KIAA1430 homologue Erp_C PF06780.11 KII85765.1 - 0.056 13.5 0.4 0.097 12.7 0.4 1.4 1 0 0 1 1 1 0 Erp protein C-terminus DotU PF09850.9 KII85765.1 - 0.078 12.7 3.7 1.8 8.3 0.0 2.6 2 1 0 2 2 2 0 Type VI secretion system protein DotU Phage_GP20 PF06810.11 KII85765.1 - 0.13 12.0 6.9 0.19 11.6 6.9 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KII85765.1 - 0.7 10.3 5.6 0.29 11.6 0.8 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 KII85765.1 - 0.71 10.2 10.8 1.3 9.4 8.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Guanylate_kin PF00625.21 KII85766.1 - 1.6e-65 220.2 0.0 2.2e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KII85766.1 - 2.2e-09 37.9 0.0 5.6e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KII85766.1 - 1.8e-05 24.9 0.0 0.00011 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KII85766.1 - 0.00029 21.1 0.0 0.00096 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KII85766.1 - 0.00065 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KII85766.1 - 0.00077 19.5 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KII85766.1 - 0.0038 17.6 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 KII85766.1 - 0.0044 17.6 0.0 0.019 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KII85766.1 - 0.0063 16.5 0.0 0.074 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KII85766.1 - 0.0097 16.4 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 KII85766.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KII85766.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KII85766.1 - 0.021 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KII85766.1 - 0.026 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KII85766.1 - 0.035 14.3 0.1 0.092 13.0 0.0 1.8 3 0 0 3 3 1 0 AAA domain Rad17 PF03215.15 KII85766.1 - 0.057 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 KII85766.1 - 0.06 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KII85766.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KII85766.1 - 0.069 12.9 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII85766.1 - 0.072 13.0 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PS-DH PF14765.6 KII85766.1 - 0.075 12.2 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase KAP_NTPase PF07693.14 KII85766.1 - 0.13 11.5 0.1 0.85 8.8 0.1 1.9 1 1 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 KII85766.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KII85766.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Pkinase PF00069.25 KII85767.1 - 2.1e-62 210.9 0.0 4.4e-62 209.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII85767.1 - 7.1e-35 120.5 0.0 9.6e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII85767.1 - 2.7e-08 33.5 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII85767.1 - 0.0004 19.3 0.1 0.00084 18.2 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII85767.1 - 0.0025 17.2 2.1 0.0034 16.8 0.1 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII85767.1 - 0.0047 16.9 0.2 0.0098 15.8 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII85767.1 - 0.039 12.9 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Mus7 PF09462.10 KII85768.1 - 2.1e-61 208.6 0.0 5.5e-61 207.2 0.0 1.7 2 0 0 2 2 2 1 Mus7/MMS22 family DUF1295 PF06966.12 KII85769.1 - 3.9e-51 173.8 3.3 5.5e-51 173.3 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KII85769.1 - 0.00016 22.1 2.9 0.00016 22.0 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KII85769.1 - 0.00052 20.0 2.6 0.0088 16.0 0.0 2.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KII85769.1 - 0.014 15.8 0.8 0.041 14.3 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PepX_N PF09168.10 KII85769.1 - 0.076 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Cofilin_ADF PF00241.20 KII85770.1 - 7.4e-06 25.8 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.29 KII85770.1 - 0.01 16.3 0.1 0.029 14.9 0.1 1.8 1 1 0 1 1 1 0 PH domain PH_11 PF15413.6 KII85770.1 - 0.048 14.1 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.13 KII85770.1 - 0.79 9.7 16.9 1.2 9.0 16.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cation_efflux PF01545.21 KII85771.1 - 2.7e-46 157.8 5.3 3.2e-34 118.4 0.4 3.5 3 1 0 3 3 3 2 Cation efflux family Fungal_trans PF04082.18 KII85772.1 - 2.3e-19 69.5 0.1 4.3e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85772.1 - 1.9e-05 24.7 12.1 3.3e-05 23.9 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ETS_PEA3_N PF04621.13 KII85772.1 - 0.33 10.8 9.3 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 PEA3 subfamily ETS-domain transcription factor N terminal domain PDCD2_C PF04194.13 KII85773.1 - 2e-41 141.9 0.0 7.4e-41 140.1 0.0 2.0 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF2486 PF10667.9 KII85773.1 - 0.0014 19.0 8.7 0.0028 17.9 8.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2486) TFIIA PF03153.13 KII85773.1 - 0.015 15.4 1.5 0.023 14.7 1.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TP_methylase PF00590.20 KII85774.1 - 3.1e-42 144.9 2.7 4.9e-42 144.3 2.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KII85774.1 - 1.1e-15 57.9 0.0 5e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KII85774.1 - 1.8e-10 40.3 0.2 4e-08 32.8 0.1 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KII85774.1 - 1.1e-09 37.5 0.0 2.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Fungal_trans PF04082.18 KII85775.1 - 6.8e-17 61.4 0.1 1.3e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII85775.1 - 0.00026 21.1 11.5 0.00046 20.3 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1648 PF07853.11 KII85775.1 - 0.18 11.5 0.3 0.61 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) ECH_1 PF00378.20 KII85778.1 - 9e-57 192.3 0.0 1.1e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII85778.1 - 5.1e-31 108.4 0.1 6.6e-28 98.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ATG16 PF08614.11 KII85779.1 - 8.8e-08 32.6 13.0 1.2e-05 25.7 10.4 2.4 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) HrpB7 PF09486.10 KII85779.1 - 8e-05 23.1 15.2 0.0036 17.7 5.9 2.2 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 KII85779.1 - 9.6e-05 21.4 9.9 0.022 13.7 6.9 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Fez1 PF06818.15 KII85779.1 - 0.0013 19.3 0.8 0.014 15.8 0.2 2.0 2 0 0 2 2 2 1 Fez1 DUF2408 PF10303.9 KII85779.1 - 0.0038 17.8 2.2 0.045 14.3 1.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2408) FH2 PF02181.23 KII85779.1 - 0.0044 16.2 6.4 0.61 9.1 3.8 2.1 2 0 0 2 2 2 2 Formin Homology 2 Domain DUF3618 PF12277.8 KII85779.1 - 0.013 15.8 4.5 0.04 14.2 4.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) APG6_N PF17675.1 KII85779.1 - 0.013 16.0 13.9 0.039 14.5 6.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region SKA1 PF07160.12 KII85779.1 - 0.013 15.3 0.3 0.048 13.5 0.3 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Atg14 PF10186.9 KII85779.1 - 0.047 12.8 5.8 0.051 12.6 2.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 KII85779.1 - 0.091 12.6 1.2 5.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Prefoldin PF02996.17 KII85779.1 - 0.16 11.9 6.3 0.26 11.2 2.6 2.5 2 1 0 2 2 2 0 Prefoldin subunit Tropomyosin PF00261.20 KII85779.1 - 0.2 11.0 14.0 0.15 11.4 6.1 2.2 2 0 0 2 2 2 0 Tropomyosin PRKG1_interact PF15898.5 KII85779.1 - 0.22 12.5 11.8 2.3 9.2 0.1 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 KII85779.1 - 0.3 9.7 3.2 0.13 10.8 0.6 1.6 2 0 0 2 2 2 0 AAA domain HIP1_clath_bdg PF16515.5 KII85779.1 - 0.33 11.6 0.1 0.33 11.6 0.1 2.9 2 1 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAT PF03127.14 KII85779.1 - 0.34 11.2 2.7 0.3 11.4 0.8 2.0 2 0 0 2 2 1 0 GAT domain MIP-T3_C PF17749.1 KII85779.1 - 0.35 10.8 5.8 6 6.8 1.4 3.0 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Acetyltransf_11 PF13720.6 KII85779.1 - 0.36 11.3 1.4 2.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_MLP1_2 PF07926.12 KII85779.1 - 0.36 10.9 14.0 2.5 8.2 0.8 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 KII85779.1 - 0.38 9.9 7.7 0.11 11.7 3.0 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region OmpH PF03938.14 KII85779.1 - 0.4 11.0 6.5 1.7 9.0 2.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 KII85779.1 - 0.41 10.7 6.7 13 5.9 4.2 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CC2-LZ PF16516.5 KII85779.1 - 0.43 11.0 4.8 13 6.2 2.4 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YscO-like PF16789.5 KII85779.1 - 0.55 10.2 6.4 9.4 6.2 0.0 2.3 2 1 0 2 2 2 0 YscO-like protein MscS_porin PF12795.7 KII85779.1 - 0.58 9.7 10.0 5.4 6.5 6.0 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HisKA_3 PF07730.13 KII85779.1 - 0.63 10.6 8.3 1.9 9.0 1.6 2.7 2 0 0 2 2 2 0 Histidine kinase Fib_alpha PF08702.10 KII85779.1 - 0.64 10.2 5.6 0.59 10.3 3.5 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rx_N PF18052.1 KII85779.1 - 0.7 10.2 3.9 24 5.3 2.3 2.4 2 0 0 2 2 2 0 Rx N-terminal domain CALCOCO1 PF07888.11 KII85779.1 - 0.75 8.6 12.2 0.82 8.5 7.7 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mod_r PF07200.13 KII85779.1 - 0.84 9.7 6.8 2.1 8.5 4.4 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CHASE3 PF05227.13 KII85779.1 - 1.1 9.1 11.1 0.78 9.6 7.7 2.0 2 0 0 2 2 2 0 CHASE3 domain ADIP PF11559.8 KII85779.1 - 1.3 9.1 10.6 0.21 11.6 4.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 KII85779.1 - 2 8.5 6.2 0.21 11.7 1.6 1.7 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Swi5 PF07061.11 KII85779.1 - 2.2 8.5 5.5 12 6.1 0.1 2.7 2 1 0 2 2 2 0 Swi5 betaPIX_CC PF16523.5 KII85779.1 - 2.4 8.1 6.2 14 5.5 0.0 3.3 2 1 0 3 3 3 0 betaPIX coiled coil Use1 PF09753.9 KII85779.1 - 2.6 7.7 10.1 0.16 11.7 5.0 1.5 2 0 0 2 2 1 0 Membrane fusion protein Use1 DUF2203 PF09969.9 KII85779.1 - 2.6 8.8 5.5 16 6.2 2.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FliJ PF02050.16 KII85779.1 - 3.2 8.0 11.6 5.8 7.2 4.6 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Tropomyosin_1 PF12718.7 KII85779.1 - 3.4 7.8 13.3 6.3 6.9 5.5 2.2 2 0 0 2 2 2 0 Tropomyosin like Metal_resist PF13801.6 KII85779.1 - 3.5 7.8 13.5 9.1 6.5 1.9 2.6 2 0 0 2 2 2 0 Heavy-metal resistance DUF4201 PF13870.6 KII85779.1 - 3.7 7.3 11.7 37 4.0 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF745 PF05335.13 KII85779.1 - 5 6.8 11.1 4.6 6.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Jnk-SapK_ap_N PF09744.9 KII85779.1 - 5.1 7.3 9.5 0.61 10.3 4.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 KII85779.1 - 6.1 4.2 10.3 0.36 8.3 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 KII85779.1 - 6.6 5.9 10.0 1.2 8.3 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) THOC7 PF05615.13 KII85779.1 - 9.3 6.5 11.2 23 5.2 3.6 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1771 PF08590.10 KII85780.1 - 7.1e-14 51.9 8.5 1.8e-13 50.7 8.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KII85780.1 - 2.8e-08 33.5 8.1 3.1e-06 27.1 1.2 2.8 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KII85780.1 - 1.1e-06 29.3 3.9 2.2e-05 25.1 0.1 2.4 1 1 1 2 2 2 1 Torus domain Smr PF01713.21 KII85780.1 - 6e-06 26.5 0.1 1.3e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KII85780.1 - 1.1e-05 25.2 6.5 0.0011 18.8 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.9 KII85780.1 - 0.0034 17.1 3.2 0.085 12.6 0.4 2.4 2 0 0 2 2 2 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 KII85780.1 - 0.0041 16.9 12.5 0.17 11.7 0.8 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KII85780.1 - 0.0053 17.2 5.9 0.14 12.7 0.8 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KII85780.1 - 0.011 16.0 3.3 0.12 12.5 3.3 2.1 1 1 0 1 1 1 0 Zinc-finger containing family Tom5 PF10642.9 KII85780.1 - 0.11 12.5 2.3 0.28 11.2 2.3 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Ras PF00071.22 KII85782.1 - 1e-51 174.7 0.0 1.3e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII85782.1 - 1.2e-20 73.9 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII85782.1 - 3.3e-07 29.9 0.0 4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KII85782.1 - 0.00044 19.7 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Skp1_POZ PF03931.15 KII85782.1 - 0.014 15.6 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain MMR_HSR1 PF01926.23 KII85782.1 - 0.022 14.8 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII85782.1 - 0.024 14.5 0.0 7.5 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KII85782.1 - 0.045 13.1 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DLIC PF05783.11 KII85782.1 - 0.066 12.0 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KII85782.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Clathrin PF00637.20 KII85783.1 - 7.5e-204 667.8 32.8 2.7e-33 114.8 0.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KII85783.1 - 2.8e-35 118.9 0.5 5.4e-07 29.6 0.1 6.9 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KII85783.1 - 1.7e-30 104.7 0.1 8.4e-30 102.5 0.1 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KII85783.1 - 1.3e-12 46.8 1.1 9.6e-12 44.1 0.0 2.8 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KII85783.1 - 0.0018 17.4 8.7 0.59 9.1 0.2 4.2 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 KII85783.1 - 0.0075 16.2 11.9 3.5 7.9 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.20 KII85783.1 - 0.022 15.0 0.7 68 4.0 0.0 5.5 6 0 0 6 6 5 0 PPR repeat TPR_1 PF00515.28 KII85783.1 - 0.024 14.5 8.8 15 5.6 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Acetyltransf_15 PF17013.5 KII85783.1 - 0.076 12.5 0.0 0.32 10.4 0.0 2.0 1 0 0 1 1 1 0 Putative acetyl-transferase TPR_8 PF13181.6 KII85783.1 - 0.16 12.3 12.5 7.8 7.0 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KII85783.1 - 0.27 11.4 15.4 42 4.6 0.4 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII85783.1 - 0.35 11.8 20.7 7.4 7.7 0.0 9.4 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII85783.1 - 6.3 7.2 11.6 68 3.9 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PQ-loop PF04193.14 KII85784.1 - 3e-14 52.5 1.3 3e-14 52.5 1.3 1.7 2 0 0 2 2 2 1 PQ loop repeat ER_lumen_recept PF00810.18 KII85784.1 - 0.028 15.3 0.5 0.034 15.0 0.5 1.2 1 0 0 1 1 1 0 ER lumen protein retaining receptor SDH_alpha PF03313.15 KII85785.1 - 1.7e-100 336.0 3.6 2.3e-100 335.6 3.6 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KII85785.1 - 2.3e-58 197.0 0.0 7.4e-58 195.3 0.0 1.9 2 0 0 2 2 2 1 Serine dehydratase beta chain TRI5 PF06330.11 KII85786.1 - 4.2e-23 81.8 0.0 5.8e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SET PF00856.28 KII85787.1 - 0.02 15.3 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 SET domain NMO PF03060.15 KII85788.1 - 9.8e-38 130.4 3.3 8e-36 124.1 3.3 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KII85788.1 - 4.7e-08 32.4 0.0 1.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KII85788.1 - 8.1e-05 21.8 0.4 0.00016 20.8 0.4 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase LSM PF01423.22 KII85789.1 - 2.5e-16 59.1 0.0 3.6e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain LAL_C2 PF18603.1 KII85789.1 - 0.0046 17.1 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 zf-C6H2 PF15801.5 KII85791.1 - 0.023 15.0 2.5 0.052 13.8 2.5 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ARL6IP6 PF15062.6 KII85793.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix SPATA6 PF14909.6 KII85794.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-assoc protein 6 Trimer_CC PF08954.11 KII85794.1 - 0.48 10.0 7.0 0.077 12.6 2.6 1.9 2 0 0 2 2 2 0 Trimerisation motif Striatin PF08232.12 KII85795.1 - 1.1 9.9 4.3 0.42 11.2 0.1 2.0 2 0 0 2 2 2 0 Striatin family Hexokinase_2 PF03727.16 KII85796.1 - 0.051 13.0 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Hexokinase THOC7 PF05615.13 KII85796.1 - 0.75 10.1 5.2 0.89 9.8 0.2 2.7 2 1 0 2 2 2 0 Tho complex subunit 7 RhoGAP PF00620.27 KII85799.1 - 2.7e-40 137.7 0.0 4.9e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KII85799.1 - 2.3e-16 60.2 0.0 5.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PX PF00787.24 KII85799.1 - 2.2e-08 34.0 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KII85799.1 - 0.0085 16.4 0.0 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain TERB2 PF15101.6 KII85799.1 - 4.3 7.3 7.3 10 6.1 7.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SHR3_chaperone PF08229.11 KII85800.1 - 1.5e-49 167.5 0.2 1.7e-49 167.4 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 TRI5 PF06330.11 KII85801.1 - 2.3e-21 76.1 0.0 2.9e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF4219 PF13961.6 KII85801.1 - 0.23 11.1 0.5 1.8 8.3 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) TRI5 PF06330.11 KII85802.1 - 2.6e-19 69.3 0.0 3.5e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) TRI5 PF06330.11 KII85803.1 - 1.3e-19 70.4 0.0 1.6e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) CPSase_L_D2 PF02786.17 KII85804.1 - 9.1e-80 267.1 0.1 2.7e-79 265.6 0.2 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KII85804.1 - 4.8e-67 225.6 0.0 8.1e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KII85804.1 - 3.8e-40 136.9 0.1 8.1e-40 135.8 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KII85804.1 - 4e-29 100.9 0.0 1.5e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KII85804.1 - 4.4e-29 101.9 0.0 1.1e-28 100.6 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KII85804.1 - 8.6e-18 63.9 6.2 2.5e-17 62.5 3.8 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KII85804.1 - 6.4e-12 45.1 6.5 2.3e-05 24.1 0.3 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KII85804.1 - 4.1e-10 39.5 0.0 8.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KII85804.1 - 4.6e-08 32.8 0.1 9.4e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KII85804.1 - 2.2e-06 28.3 0.9 0.06 14.1 0.1 2.9 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KII85804.1 - 1.3e-05 25.3 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KII85804.1 - 1.3e-05 24.5 0.6 0.0061 15.8 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 KII85804.1 - 1.7e-05 24.5 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KII85804.1 - 0.00082 19.3 3.5 0.0025 17.7 0.5 3.1 3 1 1 4 4 4 1 Glycine cleavage H-protein RnfC_N PF13375.6 KII85804.1 - 0.0075 16.2 1.0 0.036 14.0 1.1 2.1 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 KII85804.1 - 0.0075 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 KII85804.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KII85804.1 - 0.038 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KII85804.1 - 0.063 13.2 0.5 1 9.3 0.3 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.22 KII85804.1 - 0.064 13.5 1.4 0.81 9.9 0.5 3.3 2 1 0 2 2 2 0 Peptidase family M23 EamA PF00892.20 KII85805.1 - 0.00021 21.5 9.6 0.00021 21.5 9.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family MFS_1 PF07690.16 KII85806.1 - 2e-38 132.2 32.4 2e-38 132.2 32.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII85806.1 - 2.9e-13 49.5 8.3 2.9e-13 49.5 8.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KII85807.1 - 4.9e-39 134.2 27.4 4.9e-39 134.2 27.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII85807.1 - 6.8e-16 58.2 4.8 6.8e-16 58.2 4.8 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter Adeno_PIX PF03955.14 KII85807.1 - 0.23 11.7 3.8 4.1 7.6 0.1 3.2 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) OATP PF03137.20 KII85807.1 - 4.4 5.5 5.8 0.46 8.7 0.0 2.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SelP_N PF04592.14 KII85808.1 - 5.1 6.4 10.9 13 5.1 10.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TRAUB PF08164.12 KII85809.1 - 1e-30 106.0 0.1 2.6e-30 104.7 0.1 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KII85809.1 - 1e-26 94.3 3.0 2.4e-26 93.1 0.2 2.6 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ORC_WH_C PF18137.1 KII85810.1 - 4.9e-43 146.6 0.0 7.7e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KII85810.1 - 3.1e-31 108.7 0.0 5.6e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Velvet PF11754.8 KII85811.1 - 2.6e-27 96.4 0.3 4e-14 53.2 0.0 2.6 2 1 1 3 3 3 2 Velvet factor Tim17 PF02466.19 KII85812.1 - 1.6e-25 89.7 7.0 2.2e-25 89.2 7.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TPR_11 PF13414.6 KII85813.1 - 3.6e-17 61.8 3.6 5e-07 29.3 0.1 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.28 KII85813.1 - 7.1e-17 60.4 0.1 3.1e-07 29.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII85813.1 - 1.9e-16 58.7 1.5 6.6e-07 29.0 0.0 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII85813.1 - 7e-13 49.0 2.4 4.8e-05 23.9 0.6 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII85813.1 - 1.8e-11 43.6 0.1 0.026 14.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII85813.1 - 3.5e-11 43.2 4.0 0.00054 20.2 0.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII85813.1 - 1e-10 40.9 1.3 0.0029 17.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII85813.1 - 2.3e-10 40.8 1.2 0.00032 21.1 0.2 2.9 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII85813.1 - 6.7e-10 39.0 4.3 0.0016 19.1 0.0 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KII85813.1 - 1.9e-07 30.7 5.2 0.028 14.3 0.0 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 KII85813.1 - 1.1e-05 24.8 0.5 1.6e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII85813.1 - 1.8e-05 24.4 4.5 0.76 10.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII85813.1 - 6.4e-05 23.3 0.1 0.19 12.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII85813.1 - 0.00023 21.3 0.3 0.047 13.9 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KII85813.1 - 0.00067 20.0 1.9 0.19 12.4 0.1 4.3 4 1 0 4 4 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KII85813.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KII85813.1 - 0.002 18.4 1.6 0.036 14.4 0.2 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII85813.1 - 0.0089 16.2 0.2 1.2 9.3 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 KII85813.1 - 0.011 15.8 1.4 2.7 8.2 0.1 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 KII85813.1 - 0.03 14.4 0.5 3.5 7.7 0.5 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) AAA_33 PF13671.6 KII85814.1 - 1.1e-18 67.8 1.4 5.1e-10 39.7 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 KII85814.1 - 1.6e-05 25.4 0.0 0.0034 17.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 KII85814.1 - 0.00046 20.1 0.0 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 KII85814.1 - 0.016 14.5 0.0 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin tRNA_lig_kinase PF08303.11 KII85814.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_25 PF13481.6 KII85814.1 - 0.024 14.2 0.0 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KII85814.1 - 0.026 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KII85814.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 KII85814.1 - 0.039 13.8 0.1 0.073 13.0 0.1 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KII85814.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KII85814.1 - 0.067 13.6 0.1 0.54 10.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 KII85814.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_PrkA PF08298.11 KII85814.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_22 PF13401.6 KII85814.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KII85814.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ATP_bind_1 PF03029.17 KII85814.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CPT PF07931.12 KII85814.1 - 0.17 11.7 0.5 17 5.2 0.0 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein PX PF00787.24 KII85815.1 - 5.1e-22 78.0 0.0 1.4e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KII85815.1 - 2.1e-06 27.5 6.9 0.00086 18.9 1.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KII85815.1 - 0.033 13.8 0.6 0.033 13.8 0.6 1.9 2 0 0 2 2 2 0 BAR domain DUF4391 PF14335.6 KII85815.1 - 0.036 13.8 0.6 0.07 12.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) FliD_N PF02465.18 KII85815.1 - 0.047 14.4 0.0 0.55 11.0 0.0 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF5339 PF17274.2 KII85815.1 - 2.7 8.9 5.4 1.7 9.6 0.9 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5339) PX PF00787.24 KII85816.1 - 5.1e-19 68.3 0.1 9.9e-19 67.4 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KII85816.1 - 0.28 10.7 6.7 0.36 10.4 1.5 2.1 2 0 0 2 2 2 0 Vps5 C terminal like CYSTM PF12734.7 KII85817.1 - 0.0023 18.2 32.5 0.0023 18.2 32.5 4.1 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 KII85817.1 - 1.1 9.3 18.4 1.5 8.8 18.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 KII85817.1 - 2.5 8.7 6.3 2.9 8.5 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cytochrom_C1 PF02167.15 KII85818.1 - 3.4e-99 331.0 0.0 4.2e-99 330.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KII85818.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KII85818.1 - 0.013 16.6 0.1 0.036 15.2 0.1 2.0 1 1 0 1 1 1 0 Cytochrome c AAA PF00004.29 KII85819.1 - 3.3e-39 134.3 0.1 1.3e-13 51.6 0.0 5.4 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KII85819.1 - 6.5e-39 133.6 0.0 1.8e-38 132.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII85819.1 - 8.3e-27 94.6 23.3 4.8e-22 79.0 0.0 6.8 6 0 0 6 6 6 2 AAA domain AAA_lid_6 PF17866.1 KII85819.1 - 1.1e-18 67.2 2.7 2.1e-07 31.0 2.6 3.9 3 0 0 3 3 3 2 AAA lid domain AAA_19 PF13245.6 KII85819.1 - 1.3e-17 64.5 0.4 6.4e-08 33.0 0.0 5.7 5 2 1 6 6 5 3 AAA domain AAA_30 PF13604.6 KII85819.1 - 2.4e-16 60.0 14.7 9.8e-05 22.2 0.0 6.7 6 1 0 6 6 5 4 AAA domain AAA_5 PF07728.14 KII85819.1 - 5.9e-12 45.8 1.4 0.08 12.9 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KII85819.1 - 1.8e-11 43.8 0.1 0.11 11.9 0.0 4.8 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KII85819.1 - 1.9e-11 44.4 6.3 0.11 12.8 0.3 7.5 7 2 0 7 7 6 3 AAA domain Viral_helicase1 PF01443.18 KII85819.1 - 6.4e-10 39.2 0.2 0.75 9.5 0.0 6.1 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KII85819.1 - 6.4e-09 35.8 4.0 0.79 9.4 0.0 5.5 5 0 0 5 5 5 3 AAA domain AAA_18 PF13238.6 KII85819.1 - 8.7e-08 32.8 6.9 0.21 12.2 0.0 6.0 5 0 0 5 5 4 2 AAA domain RuvB_N PF05496.12 KII85819.1 - 1.9e-07 31.0 0.1 0.086 12.6 0.0 4.8 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KII85819.1 - 4.2e-07 30.3 0.1 4.5 7.7 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_33 PF13671.6 KII85819.1 - 1.7e-06 28.2 12.2 0.29 11.3 0.0 5.7 5 0 0 5 5 4 2 AAA domain IstB_IS21 PF01695.17 KII85819.1 - 2.2e-06 27.5 0.3 3.6 7.3 0.0 4.9 4 0 0 4 4 4 1 IstB-like ATP binding protein ResIII PF04851.15 KII85819.1 - 3.7e-06 27.0 0.5 0.023 14.7 0.0 4.7 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KII85819.1 - 0.00022 20.8 2.7 2.7 7.5 0.1 4.5 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_25 PF13481.6 KII85819.1 - 0.00023 20.8 5.5 1.4 8.4 0.0 5.7 4 1 1 5 5 5 1 AAA domain AAA_16 PF13191.6 KII85819.1 - 0.00092 19.6 22.8 1.9 8.8 0.1 6.6 6 0 0 6 6 5 2 AAA ATPase domain ATPase PF06745.13 KII85819.1 - 0.0059 16.0 3.8 4.2 6.7 0.0 4.4 4 0 0 4 4 4 1 KaiC MCM PF00493.23 KII85819.1 - 0.0064 15.6 0.1 0.11 11.6 0.0 2.6 3 0 0 3 3 3 1 MCM P-loop domain VirE PF05272.11 KII85819.1 - 0.01 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E AAA_28 PF13521.6 KII85819.1 - 0.012 15.8 17.8 0.67 10.2 0.0 6.3 6 0 0 6 6 5 0 AAA domain DUF2075 PF09848.9 KII85819.1 - 0.013 14.7 0.0 0.013 14.7 0.0 6.5 6 2 1 7 7 6 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 KII85819.1 - 0.014 14.2 0.0 0.035 12.9 0.0 1.6 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 KII85819.1 - 0.019 14.9 2.5 28 4.6 0.1 4.4 4 0 0 4 4 4 0 NTPase TsaE PF02367.17 KII85819.1 - 0.019 14.9 2.0 11 6.0 0.0 4.1 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KII85819.1 - 0.024 15.1 5.3 30 5.1 0.0 5.2 5 0 0 5 5 4 0 ABC transporter Torsin PF06309.11 KII85819.1 - 0.032 14.3 0.3 39 4.3 0.0 3.9 4 0 0 4 4 3 0 Torsin CbiA PF01656.23 KII85819.1 - 0.055 13.5 3.9 78 3.3 0.0 4.7 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 KII85819.1 - 0.19 11.3 4.3 4.2 7.0 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KII85819.1 - 0.87 10.0 14.0 7.1 7.1 0.0 5.7 5 0 0 5 5 4 0 AAA domain ADK PF00406.22 KII85819.1 - 2.2 8.4 4.5 84 3.2 0.1 4.0 4 0 0 4 4 4 0 Adenylate kinase Aminotran_5 PF00266.19 KII85820.1 - 4.8e-34 117.9 0.0 6.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KII85820.1 - 3.4e-05 23.9 0.7 0.00067 19.7 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain Cro PF09048.10 KII85820.1 - 0.018 15.1 0.1 0.056 13.5 0.1 1.8 1 0 0 1 1 1 0 Cro SAC3_GANP PF03399.16 KII85821.1 - 2.7e-21 76.2 4.8 1.9e-19 70.2 4.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KII85821.1 - 5.5e-07 29.7 0.1 1.6e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family tRNA_int_endo PF01974.17 KII85822.1 - 1.2e-17 63.8 0.2 3.1e-17 62.4 0.2 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KII85822.1 - 0.025 14.2 0.1 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Nop25 PF09805.9 KII85822.1 - 0.11 12.9 1.3 0.16 12.4 1.3 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) WD40 PF00400.32 KII85823.1 - 4.3e-10 40.0 14.6 0.76 10.8 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat HAND PF09110.11 KII85823.1 - 0.016 15.9 7.2 0.03 15.1 7.2 1.4 1 0 0 1 1 1 0 HAND ANAPC4_WD40 PF12894.7 KII85823.1 - 0.024 14.9 0.0 0.85 10.0 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Dynein_IC2 PF11540.8 KII85823.1 - 0.15 12.0 0.2 0.44 10.5 0.2 1.8 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 NIR_SIR PF01077.22 KII85824.1 - 1e-52 177.9 0.0 5.9e-48 162.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KII85824.1 - 4.8e-33 112.8 0.0 7.9e-16 57.7 0.0 3.0 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KII85824.1 - 2.8e-30 105.4 0.0 5.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KII85824.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Peripla_BP_6 PF13458.6 KII85824.1 - 0.022 14.5 0.8 0.51 9.9 0.1 2.6 2 0 0 2 2 2 0 Periplasmic binding protein POR_N PF01855.19 KII85824.1 - 0.03 14.1 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SQHop_cyclase_N PF13249.6 KII85825.1 - 7.8e-52 176.2 0.2 3.3e-41 141.3 0.0 3.7 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KII85825.1 - 1.7e-47 162.1 1.2 9.3e-44 149.8 1.6 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KII85825.1 - 4.2e-39 132.0 5.6 3.4e-10 39.5 0.4 6.7 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KII85825.1 - 0.00033 20.1 1.0 6.6 6.0 0.0 4.7 3 2 2 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 KII85825.1 - 0.00084 18.5 0.2 0.24 10.4 0.0 3.6 2 1 2 4 4 4 1 A-macroglobulin TED domain Actin PF00022.19 KII85826.1 - 1.1e-40 139.5 0.0 1.3e-39 136.0 0.0 1.9 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.26 KII85827.1 - 1.6e-15 56.6 0.0 1.7e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SET PF00856.28 KII85828.1 - 4.1e-05 24.0 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 SET domain bVLRF1 PF18826.1 KII85831.1 - 3.3e-66 221.7 0.0 5.1e-66 221.1 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor PMM PF03332.13 KII85832.1 - 1.3e-106 355.3 0.5 1.6e-106 355.1 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KII85832.1 - 0.00038 20.3 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 KII85832.1 - 0.066 13.3 0.2 0.35 10.9 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function, DUF600 S6PP PF05116.13 KII85832.1 - 0.21 11.1 0.0 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DNA_pol_B PF00136.21 KII85833.1 - 4.4e-148 493.8 0.1 6.2e-148 493.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KII85833.1 - 6.9e-85 285.1 0.0 1.1e-84 284.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KII85833.1 - 7.4e-18 64.8 7.6 1.5e-17 63.8 7.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KII85833.1 - 0.00032 19.7 0.5 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral C1_1 PF00130.22 KII85833.1 - 3.5 7.6 6.7 2.9 7.9 3.2 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cu PF17563.2 KII85834.1 - 0.28 11.4 0.9 0.81 10.0 1.2 1.6 2 0 0 2 2 2 0 Cupiennin Leo1 PF04004.13 KII85836.1 - 2.1e-47 161.0 0.2 2.1e-47 161.0 0.2 1.9 2 0 0 2 2 2 1 Leo1-like protein Atx10homo_assoc PF09759.9 KII85837.1 - 7.8e-24 83.6 0.0 2.8e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KII85837.1 - 0.16 12.1 3.9 2.2 8.4 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TPR_16 PF13432.6 KII85837.1 - 9.8 6.9 6.3 4 8.2 1.7 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Vma12 PF11712.8 KII85838.1 - 2.4e-13 50.4 0.0 3.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase NUDIX PF00293.28 KII85839.1 - 2.4e-12 47.0 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain BRAP2 PF07576.12 KII85840.1 - 7.9e-30 103.0 0.0 1.5e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KII85840.1 - 4.7e-19 68.5 3.2 1e-18 67.4 3.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KII85840.1 - 2.4e-08 34.2 9.5 2.4e-08 34.2 9.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII85840.1 - 2.8e-06 27.1 9.4 6.1e-06 26.0 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85840.1 - 1.5e-05 24.8 7.7 3.4e-05 23.6 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KII85840.1 - 1.8e-05 24.4 4.9 5e-05 22.9 4.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KII85840.1 - 2.1e-05 24.7 5.8 5.5e-05 23.4 5.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KII85840.1 - 6.2e-05 22.9 5.6 0.00024 21.1 5.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII85840.1 - 0.00086 19.1 6.7 0.00086 19.1 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85840.1 - 0.0038 17.2 6.7 0.0038 17.2 6.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KII85840.1 - 0.0099 15.9 3.8 0.02 15.0 3.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.22 KII85840.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UBP_var PF17807.1 KII85840.1 - 0.023 14.4 0.3 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger zf-RING_4 PF14570.6 KII85840.1 - 0.047 13.5 6.2 0.12 12.2 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rootletin PF15035.6 KII85840.1 - 0.079 13.0 14.7 0.13 12.3 14.7 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Zwint PF15556.6 KII85840.1 - 0.25 10.8 10.7 0.51 9.8 10.7 1.4 1 0 0 1 1 1 0 ZW10 interactor CSN5_C PF18323.1 KII85840.1 - 0.25 12.3 8.2 1.2 10.1 8.2 2.3 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF4407 PF14362.6 KII85840.1 - 0.47 9.8 10.6 0.79 9.0 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RasGAP_C PF03836.15 KII85840.1 - 0.55 10.4 6.3 1.9 8.6 0.8 2.3 1 1 1 2 2 2 0 RasGAP C-terminus Laminin_II PF06009.12 KII85840.1 - 0.68 9.9 9.5 1.2 9.1 9.5 1.4 1 0 0 1 1 1 0 Laminin Domain II TerY_C PF15616.6 KII85840.1 - 0.98 9.5 8.0 0.4 10.8 1.5 2.3 2 0 0 2 2 2 0 TerY-C metal binding domain Adenylsucc_synt PF00709.21 KII85840.1 - 1.9 7.3 4.4 19 4.0 4.4 2.0 1 1 0 1 1 1 0 Adenylosuccinate synthetase Tho2 PF11262.8 KII85840.1 - 2.8 7.1 7.0 4.5 6.4 7.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CREPT PF16566.5 KII85840.1 - 3.9 7.6 11.0 1.1 9.4 6.5 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 KII85840.1 - 4.4 7.4 8.2 1.4 9.0 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prok-RING_4 PF14447.6 KII85840.1 - 4.4 7.2 21.2 1.3 9.0 11.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Striatin PF08232.12 KII85840.1 - 5.8 7.5 14.5 20 5.8 14.4 1.8 1 1 0 1 1 1 0 Striatin family FUSC PF04632.12 KII85840.1 - 8.5 4.8 5.5 15 4.0 5.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cnd2 PF05786.14 KII85841.1 - 9e-182 606.6 10.4 7.1e-181 603.7 9.3 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KII85841.1 - 0.059 13.6 0.0 0.22 11.7 0.0 2.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DNA_pol_B PF00136.21 KII85843.1 - 2.6e-115 385.8 0.0 3.6e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KII85843.1 - 1.6e-61 207.3 0.0 2.7e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KII85843.1 - 6.6e-32 111.0 0.0 3.3e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KII85843.1 - 4e-20 71.6 4.6 1.6e-19 69.8 4.6 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KII85843.1 - 0.004 16.1 0.0 0.024 13.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Sporozoite_P67 PF05642.11 KII85843.1 - 0.11 10.6 2.2 0.16 10.0 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KII85843.1 - 0.61 9.9 3.0 2.5 7.9 1.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Flavin_Reduct PF01613.18 KII85844.1 - 1.4e-34 119.4 0.2 1.6e-34 119.2 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.25 KII85845.1 - 1.4e-35 122.6 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII85845.1 - 5.9e-24 84.9 0.0 7.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KII85845.1 - 9.2e-08 32.2 0.2 7e-07 29.3 0.3 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KII85845.1 - 0.0095 15.4 0.0 0.028 13.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family BTB PF00651.31 KII85846.1 - 2e-07 31.2 0.0 3.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SH3_1 PF00018.28 KII85848.1 - 1.2e-17 63.2 1.9 1.9e-07 30.6 0.2 3.2 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KII85848.1 - 1.6e-12 47.1 2.6 3.1e-05 23.7 0.2 2.9 2 1 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.30 KII85848.1 - 6.4e-11 42.5 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KII85848.1 - 6.4e-11 42.2 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KII85848.1 - 5e-07 30.3 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.17 KII85848.1 - 7.1e-07 28.8 0.4 0.0021 17.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KII85848.1 - 0.0024 18.1 5.0 0.12 12.7 0.5 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain TSC22 PF01166.18 KII85848.1 - 0.069 13.5 1.6 0.17 12.2 1.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF641 PF04859.12 KII85848.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) SAM_3 PF18016.1 KII85848.1 - 0.18 11.6 0.0 0.56 10.1 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF2947 PF11163.8 KII85849.1 - 0.25 11.2 1.1 0.53 10.1 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) AAA PF00004.29 KII85850.1 - 5e-42 143.5 0.0 9e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KII85850.1 - 2.9e-11 43.2 0.7 1.6e-10 40.8 0.0 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KII85850.1 - 1.3e-10 40.9 0.1 2.7e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KII85850.1 - 2.4e-07 30.8 0.1 3.2e-06 27.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII85850.1 - 3e-07 31.0 0.1 0.0002 21.8 0.1 2.9 3 1 1 4 4 2 1 AAA ATPase domain AAA_2 PF07724.14 KII85850.1 - 7.4e-06 26.2 0.0 4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KII85850.1 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KII85850.1 - 0.00013 22.3 0.1 0.0046 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 KII85850.1 - 0.00084 18.9 0.1 0.0034 17.0 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KII85850.1 - 0.0015 17.7 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KII85850.1 - 0.0027 17.1 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KII85850.1 - 0.0042 16.6 0.0 0.0083 15.7 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KII85850.1 - 0.0043 17.6 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KII85850.1 - 0.0044 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KII85850.1 - 0.0052 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TsaE PF02367.17 KII85850.1 - 0.0053 16.8 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KII85850.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KII85850.1 - 0.0066 16.6 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KII85850.1 - 0.012 15.6 0.0 0.043 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KII85850.1 - 0.016 14.7 0.4 0.036 13.5 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 KII85850.1 - 0.017 14.8 0.0 0.053 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KII85850.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 KII85850.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KII85850.1 - 0.022 14.5 0.1 0.057 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KII85850.1 - 0.029 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KII85850.1 - 0.043 13.2 0.7 0.17 11.2 0.0 2.2 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KII85850.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KII85850.1 - 0.05 13.2 0.4 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KII85850.1 - 0.062 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HBM PF16591.5 KII85850.1 - 0.063 12.7 0.2 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain AAA_11 PF13086.6 KII85850.1 - 0.078 12.8 0.7 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KII85850.1 - 0.079 12.2 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KII85850.1 - 0.1 13.1 0.3 14 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KII85850.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 KII85850.1 - 0.15 12.4 0.3 0.15 12.4 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sugar_tr PF00083.24 KII85851.1 - 1.3e-128 429.7 24.9 1.4e-128 429.6 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII85851.1 - 4.3e-22 78.5 37.6 2.9e-16 59.3 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyto_heme_lyase PF01265.17 KII85852.1 - 3.3e-85 286.2 7.0 8.8e-84 281.5 7.0 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Nucleo_P87 PF07267.11 KII85852.1 - 1.2 8.0 3.0 1.5 7.6 3.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_M16_M PF16187.5 KII85853.1 - 5.9e-86 288.2 1.1 6.6e-86 288.1 0.1 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KII85853.1 - 1.5e-34 119.1 0.3 1.8e-33 115.6 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KII85853.1 - 5.7e-33 114.5 0.0 7.8e-20 71.7 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Protocadherin PF08374.11 KII85854.1 - 0.0072 16.3 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Protocadherin DUF3377 PF11857.8 KII85854.1 - 0.012 15.5 0.5 0.021 14.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) CcmD PF04995.14 KII85854.1 - 0.42 10.7 2.5 1.3 9.2 2.5 1.9 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Glutaredoxin PF00462.24 KII85855.1 - 2.2e-17 63.0 0.0 3.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin MTHFR PF02219.17 KII85856.1 - 3.9e-106 354.6 0.0 5.5e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Carn_acyltransf PF00755.20 KII85857.1 - 3.7e-178 593.8 0.0 4.2e-178 593.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CNH PF00780.22 KII85858.1 - 3.5e-76 256.4 0.0 5.4e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KII85858.1 - 1.5e-42 144.9 0.0 3.6e-42 143.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KII85858.1 - 9e-34 117.3 0.0 1.4e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KII85858.1 - 9.9e-14 51.2 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Polysacc_deac_1 PF01522.21 KII85859.1 - 1.7e-29 102.3 0.0 3.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KII85859.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SOG2 PF10428.9 KII85859.1 - 1.9 7.6 12.4 2.8 7.1 12.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sec1 PF00995.23 KII85860.1 - 3.5e-132 442.6 0.0 4.1e-132 442.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Kelch_4 PF13418.6 KII85861.1 - 8.4e-10 38.5 1.0 0.0018 18.2 0.0 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KII85861.1 - 3.6e-06 27.1 3.8 1.7 9.1 0.1 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 KII85861.1 - 7.3e-06 26.1 1.9 0.42 11.0 0.0 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KII85861.1 - 4.9e-05 23.1 0.4 8.3 6.6 0.0 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KII85861.1 - 5.7e-05 22.6 0.2 1 9.0 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 KII85861.1 - 0.00037 20.4 7.2 3.7 7.7 0.0 6.3 7 0 0 7 7 7 1 Kelch motif zf-MYND PF01753.18 KII85861.1 - 0.0094 16.0 12.9 0.025 14.6 12.9 1.8 1 0 0 1 1 1 1 MYND finger DUF1579 PF07617.11 KII85861.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) zf-C6H2 PF15801.5 KII85861.1 - 0.093 13.1 14.3 0.23 11.8 14.3 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TPR_2 PF07719.17 KII85861.1 - 0.17 12.1 0.2 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PH_12 PF16457.5 KII85862.1 - 7.4e-35 120.4 0.0 1.4e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KII85862.1 - 2.7e-26 92.3 0.0 9.7e-26 90.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KII85862.1 - 1.5e-25 90.3 0.0 2.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family TUG-UBL1 PF11470.8 KII85862.1 - 0.075 13.3 0.1 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 TUG ubiquitin-like domain RA PF00788.23 KII85862.1 - 0.18 12.5 1.1 0.52 11.0 0.2 2.2 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF4327 PF14217.6 KII85862.1 - 0.78 9.9 2.9 30 4.9 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4327) Peptidase_S10 PF00450.22 KII85865.1 - 3.1e-64 217.9 0.3 4.7e-46 158.1 1.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase GCFC PF07842.12 KII85866.1 - 7.7e-82 275.0 7.5 7.7e-82 275.0 7.5 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KII85866.1 - 4.1e-07 29.8 0.4 9.2e-07 28.7 0.4 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KII85866.1 - 0.029 14.5 0.2 0.029 14.5 0.2 2.3 3 0 0 3 3 3 0 G-patch domain WD40 PF00400.32 KII85867.1 - 2e-05 25.2 0.0 0.091 13.7 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII85867.1 - 0.022 15.0 0.0 0.2 11.9 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII85867.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein vMSA PF00695.19 KII85868.1 - 0.066 12.3 2.1 0.097 11.8 2.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus WD40 PF00400.32 KII85868.1 - 0.078 13.9 2.7 2 9.4 0.8 3.2 2 1 0 2 2 2 0 WD domain, G-beta repeat DUF202 PF02656.15 KII85869.1 - 3.4e-06 27.4 0.1 8.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SLATT_5 PF18160.1 KII85869.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 Glyco_hydro_7 PF00840.20 KII85870.1 - 6.3e-210 697.4 16.6 7.1e-210 697.2 16.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 F-box-like PF12937.7 KII85871.1 - 3.6e-07 30.0 1.8 3.6e-07 30.0 1.8 2.4 2 0 0 2 2 2 1 F-box-like Actin PF00022.19 KII85873.1 - 1.8e-26 92.7 0.0 1.9e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 KII85873.1 - 2.8e-15 56.4 0.0 5.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KII85873.1 - 1.1e-06 27.8 0.2 1.5e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KII85873.1 - 0.036 14.5 0.7 0.18 12.3 0.3 2.3 3 0 0 3 3 3 0 Cell division protein FtsA DnaJ-X PF14308.6 KII85874.1 - 2.5e-64 216.6 0.8 4.1e-64 215.9 0.3 1.6 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KII85874.1 - 1.1e-23 83.2 1.7 2.9e-23 81.8 1.7 1.8 1 0 0 1 1 1 1 DnaJ domain M20_dimer PF07687.14 KII85875.1 - 2.1e-07 30.8 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KII85875.1 - 3.4e-07 30.2 1.2 6.7e-07 29.2 1.4 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 RCC1 PF00415.18 KII85876.1 - 1.3e-20 73.8 6.9 7.4e-08 32.9 0.1 6.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII85876.1 - 1.4e-08 34.3 28.2 0.028 14.2 0.6 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 KII85876.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII85877.1 - 5.4e-09 35.8 2.1 1.2e-08 34.6 2.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII85878.1 - 1.6e-08 34.3 3.1 4.4e-08 32.9 3.1 1.8 1 0 0 1 1 1 1 F-box-like FOXP-CC PF16159.5 KII85879.1 - 0.022 15.4 0.1 0.041 14.5 0.1 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF2110 PF09883.9 KII85879.1 - 0.062 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) zf-RING_UBOX PF13445.6 KII85880.1 - 3.2e-06 27.1 3.6 3.2e-06 27.1 3.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII85880.1 - 3.4e-06 27.3 9.1 6.8e-06 26.3 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII85880.1 - 5.6e-06 26.1 7.5 1.2e-05 25.1 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85880.1 - 6.2e-06 26.0 8.8 0.00012 21.9 9.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85880.1 - 0.00021 21.2 6.3 0.00049 20.0 5.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KII85880.1 - 0.00033 20.7 7.8 0.0024 18.0 8.1 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KII85880.1 - 0.0017 18.2 3.8 0.004 17.0 3.8 1.7 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KII85880.1 - 0.0027 17.5 6.7 0.012 15.4 6.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KII85880.1 - 0.0028 17.8 4.0 0.0062 16.6 4.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 DUF3552 PF12072.8 KII85880.1 - 0.011 15.2 7.1 0.022 14.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Tmpp129 PF10272.9 KII85880.1 - 0.016 14.6 5.8 0.023 14.0 5.8 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor UPF0242 PF06785.11 KII85880.1 - 0.035 14.2 1.4 0.06 13.4 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_IE-1 PF05290.11 KII85880.1 - 0.044 13.7 3.1 0.094 12.7 3.1 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KII85880.1 - 0.053 13.8 9.6 0.17 12.2 9.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Spc7 PF08317.11 KII85880.1 - 0.066 12.1 4.9 0.1 11.5 4.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4509 PF14970.6 KII85880.1 - 0.085 12.8 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) GAS PF13851.6 KII85880.1 - 0.088 12.2 5.5 0.15 11.4 5.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KII85880.1 - 0.097 10.8 0.8 0.13 10.4 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Prok-RING_4 PF14447.6 KII85880.1 - 0.11 12.4 10.0 3.3 7.6 10.0 2.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KII85880.1 - 0.14 12.0 2.1 0.25 11.2 2.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KII85880.1 - 0.55 10.3 4.5 1.6 8.8 4.5 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KII85880.1 - 0.69 9.6 6.5 0.62 9.7 5.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type F-box-like PF12937.7 KII85881.1 - 6.6e-09 35.5 3.4 2e-08 34.0 3.4 1.9 1 0 0 1 1 1 1 F-box-like FAT PF02259.23 KII85882.1 - 5.1e-121 404.1 4.0 1.2e-120 402.9 4.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KII85882.1 - 4.1e-69 233.2 0.0 1.4e-68 231.4 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KII85882.1 - 6.5e-59 198.4 4.4 8e-55 185.1 0.2 5.3 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KII85882.1 - 3.3e-40 136.5 4.9 5.6e-40 135.7 0.1 3.9 4 0 0 4 4 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 KII85882.1 - 2.1e-15 56.2 0.8 6e-15 54.8 0.8 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KII85882.1 - 3e-15 56.4 13.2 2.7e-05 24.5 0.0 9.2 8 1 2 11 11 9 6 HEAT repeats HEAT PF02985.22 KII85882.1 - 9.6e-10 37.9 19.8 0.12 12.7 0.1 10.4 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 KII85882.1 - 8.3e-08 32.6 23.1 0.00028 21.3 0.3 10.0 11 1 1 12 12 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KII85882.1 - 5.2e-07 30.2 0.0 9.8 6.9 0.0 7.1 6 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KII85882.1 - 3.3e-06 27.3 0.8 0.05 13.6 0.1 4.5 3 1 0 4 4 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KII85882.1 - 4.8e-06 25.4 5.4 0.29 9.6 0.0 4.0 3 1 1 4 4 4 3 Adaptin N terminal region TPR_19 PF14559.6 KII85882.1 - 0.0013 19.2 0.3 0.16 12.5 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat CLASP_N PF12348.8 KII85882.1 - 0.0023 17.5 4.0 13 5.2 0.0 5.7 6 0 0 6 6 6 0 CLASP N terminal UME PF08064.13 KII85882.1 - 0.0023 17.8 6.6 6.4 6.8 0.0 5.5 5 1 0 5 5 5 1 UME (NUC010) domain DUF3384 PF11864.8 KII85882.1 - 0.0058 15.6 0.3 0.26 10.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) MOR2-PAG1_C PF14225.6 KII85882.1 - 0.016 15.1 1.4 0.099 12.5 0.0 2.9 3 0 0 3 3 3 0 Cell morphogenesis C-terminal RTP1_C1 PF10363.9 KII85882.1 - 0.019 15.1 0.3 27 5.0 0.0 5.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 KII85882.1 - 0.037 13.1 0.7 0.63 9.1 0.0 3.5 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) IBR PF01485.21 KII85884.1 - 1.1e-14 54.4 32.1 2.3e-08 34.2 4.8 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RRM_1 PF00076.22 KII85884.1 - 7.4e-12 44.9 0.0 7.8e-07 28.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 KII85884.1 - 1.1e-06 28.6 9.4 1.1e-06 28.6 9.4 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KII85884.1 - 2.6e-05 24.3 6.4 2.6e-05 24.3 6.4 4.4 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KII85884.1 - 6.3e-05 22.8 8.2 6.3e-05 22.8 8.2 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII85884.1 - 0.00061 20.1 6.1 0.00061 20.1 6.1 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII85884.1 - 0.00061 19.6 6.8 0.00061 19.6 6.8 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85884.1 - 0.0033 17.2 6.5 0.0033 17.2 6.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85884.1 - 0.014 15.4 7.4 0.014 15.4 7.4 3.4 3 0 0 3 3 3 0 zinc-RING finger domain FAD_binding_3 PF01494.19 KII85885.1 - 3.6e-21 75.8 2.1 2.7e-11 43.3 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KII85885.1 - 7.7e-09 35.1 0.4 4.6e-06 25.9 0.1 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.17 KII85885.1 - 3.6e-05 23.1 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KII85885.1 - 5e-05 23.3 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KII85885.1 - 0.00017 20.6 0.5 0.0023 16.8 0.2 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KII85885.1 - 0.0002 20.7 0.0 0.00051 19.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KII85885.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KII85885.1 - 0.00063 19.4 2.3 0.0024 17.5 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII85885.1 - 0.0026 18.3 0.1 0.012 16.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII85885.1 - 0.0038 17.4 0.5 0.011 16.0 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII85885.1 - 0.0039 16.5 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII85885.1 - 0.034 12.9 0.2 0.063 12.0 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF3220 PF11516.8 KII85885.1 - 0.053 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Hpt PF01627.23 KII85885.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Hpt domain Sec6 PF06046.13 KII85886.1 - 2.3e-152 508.3 4.8 2.3e-152 508.3 4.8 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF885 PF05960.11 KII85886.1 - 0.0032 17.2 4.9 0.012 15.3 0.3 2.6 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF885) SKA2 PF16740.5 KII85886.1 - 0.0048 16.7 3.1 1.8 8.4 0.3 3.8 3 0 0 3 3 3 2 Spindle and kinetochore-associated protein 2 Vps53_N PF04100.12 KII85886.1 - 0.0055 15.7 6.3 0.48 9.3 0.8 2.4 2 0 0 2 2 2 2 Vps53-like, N-terminal HECT PF00632.25 KII85886.1 - 0.039 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF1759 PF03564.15 KII85886.1 - 4.1 7.3 6.3 6.7 6.6 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1759) CN_hydrolase PF00795.22 KII85887.1 - 3.8e-39 134.6 0.0 5.8e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KII85887.1 - 5.1e-22 78.2 0.0 1.7e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Pyridoxal_deC PF00282.19 KII85888.1 - 2.4e-103 345.7 0.0 2.9e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 KII85888.1 - 0.0018 17.1 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ACC_central PF08326.12 KII85890.1 - 3e-249 829.1 0.0 3.8e-249 828.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KII85890.1 - 4.2e-171 569.9 0.0 5.5e-171 569.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KII85890.1 - 3.6e-49 167.1 0.0 6.8e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KII85890.1 - 2e-28 99.1 0.1 4.5e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KII85890.1 - 2.2e-20 72.7 0.0 1.4e-19 70.2 0.0 2.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KII85890.1 - 4.2e-15 55.3 0.0 9.2e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KII85890.1 - 0.0051 16.9 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 KII85890.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KII85890.1 - 0.094 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DHO_dh PF01180.21 KII85891.1 - 8.1e-96 320.7 0.0 9.8e-96 320.4 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KII85891.1 - 0.094 11.7 0.1 0.4 9.7 0.3 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase TMF_DNA_bd PF12329.8 KII85891.1 - 0.17 11.9 2.7 0.69 10.0 2.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Lipase3_N PF03893.16 KII85892.1 - 0.07 13.2 0.3 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Lipase 3 N-terminal region Mistic PF11458.8 KII85892.1 - 0.18 11.8 0.1 0.32 11.0 0.1 1.3 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Dynein_light PF01221.18 KII85894.1 - 5.7e-37 125.9 0.4 6.2e-37 125.8 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 He_PIG PF05345.12 KII85895.1 - 7.2e-08 32.5 21.0 2.1e-05 24.6 3.7 5.9 6 0 0 6 6 6 3 Putative Ig domain HEAT PF02985.22 KII85896.1 - 1.4e-14 52.9 15.4 0.0055 16.9 0.0 9.8 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 KII85896.1 - 2.7e-14 53.3 6.7 0.0042 17.5 0.0 8.0 5 3 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 KII85896.1 - 2e-13 50.5 22.2 2e-05 25.0 0.1 11.3 11 1 1 12 12 12 3 HEAT-like repeat IBN_N PF03810.19 KII85896.1 - 3.2e-12 46.2 0.7 7.5e-10 38.6 0.2 3.8 3 1 1 4 4 4 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KII85896.1 - 5.7e-09 36.2 0.1 0.0016 18.5 0.0 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 KII85896.1 - 4.9e-06 25.9 3.9 0.22 10.6 0.3 4.4 3 2 0 3 3 3 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 KII85896.1 - 4.1e-05 24.1 0.1 3.1 8.4 0.0 5.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KII85896.1 - 0.0001 22.1 0.9 0.015 15.0 0.0 4.0 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis GRIP PF01465.20 KII85896.1 - 0.071 13.0 0.0 24 4.9 0.0 3.5 3 0 0 3 3 3 0 GRIP domain Importin_rep_4 PF18808.1 KII85896.1 - 0.13 12.5 0.5 13 6.2 0.2 3.4 3 0 0 3 3 3 0 Importin repeat Cohesin_HEAT PF12765.7 KII85896.1 - 0.13 12.5 0.0 0.77 10.1 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 KII85896.1 - 1.1 9.4 10.7 45 4.3 0.0 6.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF1631 PF07793.11 KII85898.1 - 1.4 7.3 7.7 1.1 7.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) DUF4900 PF16241.5 KII85899.1 - 0.13 12.6 5.3 38 4.7 0.1 4.3 1 1 5 6 6 6 0 Domain of unknown function (DUF4900) CPSF100_C PF13299.6 KII85900.1 - 0.078 13.2 1.4 13 5.9 2.1 2.4 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4770 PF15994.5 KII85900.1 - 1 9.6 7.3 2 8.6 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) GPI-anchored PF10342.9 KII85901.1 - 2.4e-05 25.0 0.3 5e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pro-kuma_activ PF09286.11 KII85902.1 - 2.3e-35 122.0 0.1 2.4e-33 115.4 0.0 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII85902.1 - 6.4e-09 35.5 1.2 1.1e-08 34.7 1.2 1.4 1 0 0 1 1 1 1 Subtilase family Acetyltransf_7 PF13508.7 KII85903.1 - 0.00043 20.7 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII85903.1 - 0.00048 20.1 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII85903.1 - 0.0034 17.6 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HAD_2 PF13419.6 KII85904.1 - 2.2e-09 37.7 0.0 6.1e-09 36.2 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII85904.1 - 3.4e-07 30.8 0.1 5.8e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII85904.1 - 1.2e-05 25.3 0.2 1.9e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Amidase PF01425.21 KII85905.1 - 9.2e-73 245.7 10.6 9.5e-72 242.4 10.6 2.0 1 1 0 1 1 1 1 Amidase ABM PF03992.16 KII85906.1 - 6.5e-07 29.4 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KII85906.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 ABM PF03992.16 KII85907.1 - 7.9e-08 32.3 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase NIPSNAP PF07978.13 KII85907.1 - 0.015 15.5 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 NIPSNAP DUF4937 PF16291.5 KII85907.1 - 0.077 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 LRR_8 PF13855.6 KII85908.1 - 1.4e-10 40.8 2.7 1.5e-09 37.4 1.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KII85908.1 - 2.9e-08 33.9 3.4 0.0022 18.4 0.7 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KII85908.1 - 0.0026 17.3 0.9 0.004 16.7 0.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Corona_nucleoca PF00937.18 KII85908.1 - 0.032 13.3 1.1 0.05 12.7 1.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Serglycin PF04360.12 KII85908.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Serglycin LRR_1 PF00560.33 KII85908.1 - 0.066 13.8 2.5 4.3 8.3 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 KII85909.1 - 2.3e-09 37.0 2.5 1e-06 28.5 0.6 2.5 2 0 0 2 2 2 2 F-box-like EAL PF00563.20 KII85909.1 - 0.13 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 EAL domain Metallophos PF00149.28 KII85910.1 - 9.2e-14 52.4 0.2 1.5e-13 51.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII85910.1 - 0.00039 20.7 0.1 0.0054 16.9 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.20 KII85911.1 - 9.9e-09 35.5 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 Glyco_hydro_16 PF00722.21 KII85912.1 - 1.1e-34 119.4 0.1 1.5e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AIP3 PF03915.13 KII85913.1 - 4e-151 503.8 3.5 7.2e-151 502.9 3.5 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Syntaxin-6_N PF09177.11 KII85913.1 - 0.0074 16.8 12.5 0.51 10.9 3.6 4.5 3 1 0 3 3 3 2 Syntaxin 6, N-terminal HBM PF16591.5 KII85913.1 - 0.038 13.4 3.9 0.035 13.5 1.6 2.1 2 0 0 2 2 2 0 Helical bimodular sensor domain Baculo_PEP_C PF04513.12 KII85913.1 - 0.039 14.0 10.0 1.5 8.8 1.3 4.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ISG65-75 PF11727.8 KII85913.1 - 0.098 11.9 0.9 0.23 10.6 0.8 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein Syntaxin PF00804.25 KII85913.1 - 0.11 12.2 10.9 3.8 7.1 0.3 4.2 2 1 1 3 3 3 0 Syntaxin DUF1664 PF07889.12 KII85913.1 - 0.12 12.4 9.9 0.12 12.4 3.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KII85913.1 - 0.12 12.7 9.0 0.99 9.7 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) OmpH PF03938.14 KII85913.1 - 0.28 11.5 13.5 0.56 10.5 0.3 3.9 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) LPP PF04728.13 KII85913.1 - 0.89 10.0 7.9 9.1 6.8 0.5 3.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF3245 PF11595.8 KII85913.1 - 1.2 9.6 8.8 0.39 11.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) APG6_N PF17675.1 KII85913.1 - 1.6 9.2 10.8 14 6.2 7.3 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region APG17 PF04108.12 KII85913.1 - 1.8 7.6 13.7 5.3 6.1 0.2 3.5 3 1 1 4 4 4 0 Autophagy protein Apg17 Lectin_N PF03954.14 KII85913.1 - 1.9 8.2 5.2 3 7.6 2.1 3.0 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain NPV_P10 PF05531.12 KII85913.1 - 2 8.9 13.4 4 8.0 4.0 4.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.24 KII85913.1 - 2.2 8.2 5.5 0.35 10.8 0.7 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FlgN PF05130.12 KII85913.1 - 4.3 7.8 6.0 3.9 8.0 0.0 3.6 3 1 1 4 4 4 0 FlgN protein CdvA PF18822.1 KII85913.1 - 5.4 6.9 9.4 8.4 6.3 0.1 3.8 3 1 0 3 3 3 0 CdvA-like coiled-coil domain BTB PF00651.31 KII85914.1 - 0.00039 20.6 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CorA PF01544.18 KII85915.1 - 2.3e-10 40.3 4.8 1.2e-09 38.0 4.8 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein STE2 PF02116.15 KII85915.1 - 0.037 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR ArsB PF02040.15 KII85916.1 - 5.4e-09 35.9 19.6 6.8e-05 22.4 8.0 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein FAD_binding_3 PF01494.19 KII85917.1 - 2.3e-86 290.2 0.0 4e-86 289.4 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.12 KII85917.1 - 8.1e-37 126.8 0.0 1.3e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KII85917.1 - 3.8e-07 29.5 2.0 9.4e-07 28.2 2.0 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KII85917.1 - 9.4e-07 27.9 0.8 1.4e-06 27.3 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KII85917.1 - 2.7e-06 27.5 1.2 4.3e-06 26.9 0.2 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII85917.1 - 1.5e-05 24.4 0.6 2.9e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII85917.1 - 2.8e-05 23.9 1.2 0.00017 21.3 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII85917.1 - 4.4e-05 22.8 0.6 7.3e-05 22.1 0.1 1.6 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KII85917.1 - 0.00011 21.5 0.1 0.00044 19.6 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KII85917.1 - 0.00026 20.2 1.1 0.00058 19.0 1.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 KII85917.1 - 0.00049 19.3 1.2 0.00089 18.4 1.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KII85917.1 - 0.0011 18.4 0.9 0.0019 17.6 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII85917.1 - 0.0012 18.1 0.5 0.0024 17.2 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII85917.1 - 0.003 18.1 0.2 0.006 17.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KII85917.1 - 0.0048 16.5 0.2 0.0085 15.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KII85917.1 - 0.0075 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KII85917.1 - 0.012 15.5 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KII85917.1 - 0.048 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 KII85917.1 - 0.06 13.8 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 KII85917.1 - 0.062 13.8 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain FeoB_associated PF12669.7 KII85917.1 - 0.076 13.4 5.3 0.14 12.5 5.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SE PF08491.10 KII85917.1 - 0.22 10.6 0.0 1.9 7.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Clr2_transil PF16761.5 KII85918.1 - 2.9e-25 88.9 0.8 5.3e-25 88.0 0.8 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KII85918.1 - 6.4e-08 33.5 0.2 9.8e-07 29.7 0.0 3.0 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 MBOAT PF03062.19 KII85919.1 - 3e-37 128.8 14.4 3e-37 128.8 14.4 2.5 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KII85919.1 - 3.3e-05 24.1 3.7 3.3e-05 24.1 3.7 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ARID PF01388.21 KII85919.1 - 0.02 15.6 0.1 0.34 11.6 0.0 2.4 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain TPR_19 PF14559.6 KII85920.1 - 2e-11 44.3 0.7 6.5e-06 26.6 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII85920.1 - 9.5e-07 29.1 5.6 5.7 8.0 0.1 6.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII85920.1 - 2.1e-06 28.3 1.9 0.00016 22.3 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII85920.1 - 9.2e-06 25.4 0.2 0.75 10.1 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII85920.1 - 8.7e-05 22.1 0.1 0.0025 17.5 0.0 2.6 1 1 1 2 2 2 1 TPR repeat TPR_21 PF09976.9 KII85920.1 - 0.00028 20.7 0.3 0.54 9.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 KII85920.1 - 0.0014 18.8 0.0 0.012 15.8 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KII85920.1 - 0.002 18.4 0.7 0.025 14.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII85920.1 - 0.0025 17.9 0.5 1.2 9.3 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII85920.1 - 0.0026 17.8 0.1 1.9 8.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII85920.1 - 0.0084 16.4 0.1 5.7 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HemY_N PF07219.13 KII85920.1 - 0.029 14.6 1.9 0.11 12.7 0.5 2.6 2 1 1 3 3 3 0 HemY protein N-terminus TPR_20 PF14561.6 KII85920.1 - 0.098 13.0 2.6 0.61 10.4 0.1 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KII85920.1 - 0.14 12.1 0.5 0.74 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 KII85920.1 - 0.4 10.5 2.5 0.41 10.4 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_6 PF13174.6 KII85920.1 - 1 10.2 5.1 2.5 8.9 0.0 4.0 6 0 0 6 6 4 0 Tetratricopeptide repeat KAR9 PF08580.10 KII85921.1 - 2.3e-24 86.0 37.8 2.3e-24 86.0 37.8 3.4 3 1 0 3 3 3 2 Yeast cortical protein KAR9 GAS2 PF02187.17 KII85921.1 - 0.036 14.2 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Helo_like_N PF17111.5 KII85921.1 - 0.84 9.0 4.7 0.97 8.8 2.2 2.2 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins BCS1_N PF08740.11 KII85922.1 - 5.9e-46 156.8 2.5 1e-45 156.1 2.5 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KII85922.1 - 5.4e-15 56.0 0.0 1.5e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII85922.1 - 0.0044 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KII85922.1 - 0.013 15.4 0.2 0.061 13.2 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KII85922.1 - 0.02 14.7 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KII85922.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KII85922.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KII85922.1 - 0.045 12.9 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KII85922.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KII85922.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KII85922.1 - 0.072 13.1 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KII85922.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PAP2 PF01569.21 KII85923.1 - 2e-13 50.2 9.6 2e-13 50.2 9.6 1.7 1 1 0 1 1 1 1 PAP2 superfamily Pantoate_ligase PF02569.15 KII85924.1 - 1.8e-90 302.8 0.0 2e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase MacB_PCD PF12704.7 KII85924.1 - 0.066 13.6 0.2 0.58 10.5 0.0 2.1 2 0 0 2 2 2 0 MacB-like periplasmic core domain Ribonuc_P_40 PF08584.11 KII85925.1 - 1.2e-32 113.4 0.0 1.5e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Rep-A_N PF04057.12 KII85927.1 - 3.9e-08 33.2 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.9 KII85927.1 - 0.0058 16.6 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD BRCA-2_OB1 PF09103.10 KII85927.1 - 0.047 13.6 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF5521 PF17659.1 KII85927.1 - 0.084 10.7 0.0 0.09 10.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Spermine_synth PF01564.17 KII85927.1 - 0.11 11.8 0.0 0.45 9.9 0.0 1.7 1 1 1 2 2 2 0 Spermine/spermidine synthase domain VPS9 PF02204.18 KII85928.1 - 1.3e-30 105.7 0.1 2e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KII85928.1 - 1.3e-17 63.9 0.8 2.3e-17 63.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 KII85928.1 - 3.5e-09 36.2 0.0 8.1e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 KII85928.1 - 0.00052 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif MFS_1 PF07690.16 KII85929.1 - 1.6e-32 112.9 35.7 2e-32 112.5 35.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.9 KII85929.1 - 2.8 8.2 5.7 2 8.7 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF998 PF06197.13 KII85929.1 - 4.8 6.8 26.4 3 7.4 10.4 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF998) HMG_CoA_synt_C PF08540.10 KII85933.1 - 5.4e-85 285.4 0.2 1.1e-84 284.4 0.2 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KII85933.1 - 2e-83 278.5 0.0 2.9e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal PS_Dcarbxylase PF02666.15 KII85933.1 - 0.046 13.3 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase ACP_syn_III PF08545.10 KII85933.1 - 0.19 11.6 0.7 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1752 PF08550.10 KII85934.1 - 1e-07 31.7 10.2 1.8e-07 30.8 10.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Spo7 PF03907.13 KII85936.1 - 0.018 14.6 1.5 2 7.9 0.2 2.5 2 0 0 2 2 2 0 Spo7-like protein Wzz PF02706.15 KII85936.1 - 2.2 8.6 5.2 4 7.8 0.2 2.6 2 0 0 2 2 2 0 Chain length determinant protein DUF373 PF04123.13 KII85936.1 - 2.7 7.3 11.0 3.9 6.8 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) MFS_1 PF07690.16 KII85937.1 - 5.3e-31 107.8 31.5 9e-31 107.1 31.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily BTB PF00651.31 KII85941.1 - 2.7e-06 27.6 0.0 5.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Peroxidase_2 PF01328.17 KII85942.1 - 0.007 16.9 0.0 0.01 16.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Dynamin_N PF00350.23 KII85944.1 - 1.1e-26 93.9 0.0 3e-26 92.5 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KII85944.1 - 1.4e-22 80.3 0.0 7.3e-22 77.9 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 KII85944.1 - 6.2e-08 32.7 0.2 1.9e-07 31.1 0.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII85944.1 - 1.9e-05 24.7 0.0 0.00013 22.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KII85944.1 - 0.049 14.2 0.1 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KII85944.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KII85944.1 - 0.12 12.6 4.7 0.28 11.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KII85944.1 - 2.3 8.5 7.1 0.62 10.4 0.1 3.3 2 2 0 2 2 2 0 AAA ATPase domain BTB PF00651.31 KII85945.1 - 8.3e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII85946.1 - 4.8e-09 36.4 0.0 8.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.21 KII85947.1 - 3e-15 56.7 1.4 3e-15 56.7 1.4 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PACT_coil_coil PF10495.9 KII85948.1 - 1.2e-18 67.5 1.0 1.1e-16 61.2 0.0 4.3 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein HMMR_N PF15905.5 KII85948.1 - 0.00019 21.1 13.0 0.00019 21.1 13.0 7.1 3 2 4 7 7 7 2 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 KII85948.1 - 0.003 17.6 4.2 0.003 17.6 4.2 10.0 7 1 1 10 10 10 4 Laminin Domain II AAA_13 PF13166.6 KII85948.1 - 0.016 13.9 0.0 0.016 13.9 0.0 6.2 1 1 3 6 6 6 0 AAA domain Ribonucleas_3_2 PF11469.8 KII85948.1 - 0.024 15.0 0.1 0.024 15.0 0.1 2.4 3 0 0 3 3 3 0 Ribonuclease III WD40_alt PF14077.6 KII85948.1 - 0.13 12.1 1.1 9.1 6.2 0.2 3.8 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4988 PF16378.5 KII85948.1 - 0.14 11.8 0.1 0.14 11.8 0.1 4.9 6 0 0 6 6 6 0 Domain of unknown function SNARE PF05739.19 KII85948.1 - 1.2 9.1 8.0 2.5 8.1 0.6 4.3 3 0 0 3 3 3 0 SNARE domain DEAD PF00270.29 KII85949.1 - 4e-07 30.0 0.0 4.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII85949.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII85950.1 - 2.3e-10 40.8 0.0 3.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TIR PF01582.20 KII85950.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 TIR domain ETC_C1_NDUFA5 PF04716.14 KII85951.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region 5_nucleotid_C PF02872.18 KII85951.1 - 0.15 12.3 0.1 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain NmrA PF05368.13 KII85952.1 - 1.9e-45 155.2 0.0 3.2e-45 154.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII85952.1 - 2.7e-20 73.0 0.0 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KII85952.1 - 0.097 13.1 0.5 0.16 12.4 0.5 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KII85952.1 - 0.15 12.2 0.2 0.24 11.5 0.2 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus BTB PF00651.31 KII85953.1 - 9.5e-08 32.3 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain ESCRT-II PF05871.12 KII85954.1 - 8.5e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Glyco_hydro_35 PF01301.19 KII85955.1 - 1.4e-74 251.5 1.6 2.1e-74 251.0 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KII85955.1 - 5.8e-49 165.4 1.4 5e-25 88.3 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KII85955.1 - 3.1e-45 154.2 4.6 5.8e-45 153.3 4.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KII85955.1 - 1.7e-18 65.9 0.2 2.6e-17 62.1 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KII85955.1 - 0.005 16.3 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2057 PF09829.9 KII85955.1 - 0.053 13.7 0.2 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF4470 PF14737.6 KII85956.1 - 3.2e-24 84.9 0.0 8.3e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KII85956.1 - 1.8e-11 43.9 13.7 4.5e-11 42.6 13.7 1.8 1 0 0 1 1 1 1 MYND finger DUF4123 PF13503.6 KII85956.1 - 0.051 14.0 0.6 0.22 12.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4123) zf-C6H2 PF15801.5 KII85956.1 - 1.5 9.2 10.2 3.5 8.0 10.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C3HC4_4 PF15227.6 KII85958.1 - 3.1e-09 36.8 3.4 5.9e-09 36.0 3.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KII85958.1 - 6.7e-09 35.5 3.3 6.7e-09 35.5 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII85958.1 - 1.2e-08 34.8 3.7 2.2e-08 34.0 3.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII85958.1 - 2.2e-07 30.6 3.4 4.2e-07 29.7 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII85958.1 - 1.3e-06 28.2 3.5 1.3e-06 28.2 3.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII85958.1 - 1.5e-06 28.4 3.6 1.5e-06 28.4 3.6 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KII85958.1 - 1e-05 25.4 2.5 2.2e-05 24.3 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Alanine_zipper PF11839.8 KII85958.1 - 0.00017 21.9 16.7 0.00024 21.4 16.7 1.2 1 0 0 1 1 1 1 Alanine-zipper, major outer membrane lipoprotein Prok-RING_4 PF14447.6 KII85958.1 - 0.00021 21.1 4.9 0.00035 20.4 4.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KII85958.1 - 0.0033 17.3 1.0 0.0056 16.5 1.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein KfrA_N PF11740.8 KII85958.1 - 0.0056 17.3 8.8 0.0065 17.1 8.8 1.1 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Peptidase_S66 PF02016.15 KII85958.1 - 0.029 14.5 0.2 0.044 13.9 0.2 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain zf-RING_11 PF17123.5 KII85958.1 - 0.029 14.1 4.7 0.074 12.8 4.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger Borrelia_P83 PF05262.11 KII85958.1 - 0.053 12.0 3.1 0.056 11.9 3.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein XhlA PF10779.9 KII85958.1 - 0.31 11.3 6.6 0.7 10.1 6.6 1.6 1 1 0 1 1 1 0 Haemolysin XhlA NARP1 PF12569.8 KII85958.1 - 0.81 8.5 7.0 0.96 8.3 7.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sugarporin_N PF11471.8 KII85958.1 - 1 9.4 19.4 1.8 8.6 6.6 2.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension PGBA_C PF15437.6 KII85958.1 - 1.1 9.7 15.4 6.1 7.3 15.4 1.9 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF1631 PF07793.11 KII85960.1 - 0.012 14.1 6.9 0.02 13.3 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-RING_UBOX PF13445.6 KII85961.1 - 2.5e-08 33.8 4.5 2.5e-08 33.8 4.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII85961.1 - 7.1e-08 32.7 8.1 1.3e-07 31.8 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII85961.1 - 8.3e-08 32.0 7.3 1.3e-07 31.3 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85961.1 - 3.1e-07 30.1 8.3 6.7e-07 29.0 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII85961.1 - 4.1e-07 30.0 9.2 7.7e-07 29.2 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KII85961.1 - 8.8e-07 28.7 7.7 1.7e-06 27.8 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85961.1 - 8.9e-06 25.6 6.8 1.7e-05 24.7 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII85961.1 - 0.00029 20.6 8.0 0.00059 19.6 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CCDC144C PF14915.6 KII85961.1 - 0.0011 18.2 5.2 0.0015 17.7 5.2 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region MscS_porin PF12795.7 KII85961.1 - 0.016 14.8 5.8 0.033 13.7 5.8 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain zf-rbx1 PF12678.7 KII85961.1 - 0.022 15.0 5.6 0.074 13.4 5.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain V_ATPase_I PF01496.19 KII85961.1 - 0.032 12.2 2.2 0.043 11.7 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_6 PF14835.6 KII85961.1 - 0.047 13.6 4.3 0.094 12.6 4.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HOOK PF05622.12 KII85961.1 - 0.056 11.6 8.2 0.075 11.2 8.2 1.1 1 0 0 1 1 1 0 HOOK protein COG2 PF06148.11 KII85961.1 - 0.065 13.3 1.4 0.38 10.9 0.3 2.1 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 KII85961.1 - 0.24 10.9 6.2 0.36 10.4 6.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Auto_anti-p27 PF06677.12 KII85961.1 - 0.27 11.4 1.5 0.31 11.2 0.0 1.9 2 1 0 2 2 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_4 PF14570.6 KII85961.1 - 0.27 11.1 4.9 0.74 9.7 4.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2730 PF10805.8 KII85961.1 - 0.29 11.3 1.9 0.7 10.0 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4472 PF14739.6 KII85961.1 - 0.29 11.9 10.5 5.1 7.9 5.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Tropomyosin_1 PF12718.7 KII85961.1 - 0.29 11.3 12.8 0.89 9.7 7.3 2.2 1 1 0 2 2 2 0 Tropomyosin like T3SSipB PF16535.5 KII85961.1 - 0.32 11.5 8.8 0.3 11.5 7.8 1.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB ERM PF00769.19 KII85961.1 - 0.49 10.2 15.7 1 9.1 15.7 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 KII85961.1 - 0.62 9.4 12.1 7 5.9 8.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 KII85961.1 - 0.64 10.5 10.7 0.72 10.3 7.2 2.4 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zinc_ribbon_4 PF13717.6 KII85961.1 - 0.67 9.9 2.6 21 5.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF3584 PF12128.8 KII85961.1 - 0.73 7.3 9.7 0.98 6.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NBP1 PF08537.10 KII85961.1 - 0.75 9.1 5.0 1 8.7 2.6 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 HALZ PF02183.18 KII85961.1 - 0.77 10.0 4.3 0.28 11.4 0.6 2.2 2 1 1 3 3 1 0 Homeobox associated leucine zipper zf-Nse PF11789.8 KII85961.1 - 0.84 9.5 5.2 4.3 7.2 5.4 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DHR10 PF18595.1 KII85961.1 - 0.92 9.6 15.8 2.6 8.2 11.7 2.2 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 KII85961.1 - 0.96 8.3 10.1 4.9 5.9 5.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 KII85961.1 - 1.2 8.4 7.7 0.69 9.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 KII85961.1 - 1.4 9.3 8.5 2.4 8.6 8.5 1.4 1 0 0 1 1 1 0 Fez1 SHE3 PF17078.5 KII85961.1 - 1.8 8.2 6.4 12 5.5 3.2 2.1 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 HMMR_N PF15905.5 KII85961.1 - 1.9 7.9 14.9 0.012 15.1 6.8 1.4 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal DivIC PF04977.15 KII85961.1 - 2.3 8.0 10.5 0.19 11.5 0.8 2.3 2 0 0 2 2 2 0 Septum formation initiator zf-RING_10 PF16685.5 KII85961.1 - 2.4 8.3 6.0 4.5 7.5 5.2 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 TelA PF05816.11 KII85961.1 - 3 6.8 7.2 16 4.5 5.7 2.0 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) XhlA PF10779.9 KII85961.1 - 3.3 8.0 3.9 7.9 6.8 3.9 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF4407 PF14362.6 KII85961.1 - 6.4 6.0 11.5 16 4.7 11.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_UBOX PF13445.6 KII85962.1 - 4.3e-08 33.0 2.1 4.3e-08 33.0 2.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII85962.1 - 2.4e-07 30.5 2.0 5.8e-07 29.3 2.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII85962.1 - 3.4e-07 30.3 3.4 3.4e-07 30.3 3.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KII85962.1 - 9e-07 28.6 1.6 9e-07 28.6 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85962.1 - 1e-06 28.6 2.2 1.9e-06 27.8 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HALZ PF02183.18 KII85962.1 - 1.3e-05 25.3 8.9 0.0054 16.9 0.1 4.1 3 1 1 4 4 4 2 Homeobox associated leucine zipper zf-RING_2 PF13639.6 KII85962.1 - 1.5e-05 25.2 8.7 8e-05 22.9 8.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII85962.1 - 3.9e-05 23.4 8.8 0.00053 19.8 8.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin PF00261.20 KII85962.1 - 0.00084 18.8 52.4 0.0013 18.1 35.4 2.5 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.6 KII85962.1 - 0.0021 17.4 6.6 0.0021 17.4 6.6 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Scaffolding_pro PF11418.8 KII85962.1 - 0.0068 16.9 0.4 0.0068 16.9 0.4 2.2 2 0 0 2 2 2 1 Phi29 scaffolding protein SHE3 PF17078.5 KII85962.1 - 0.016 14.9 5.6 0.016 14.9 5.6 2.5 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 zf-RING_6 PF14835.6 KII85962.1 - 0.032 14.1 1.8 0.032 14.1 1.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Alanine_zipper PF11839.8 KII85962.1 - 0.056 13.8 74.3 0.11 12.8 23.7 4.8 2 1 2 4 4 4 0 Alanine-zipper, major outer membrane lipoprotein zf-RING_11 PF17123.5 KII85962.1 - 0.17 11.6 3.6 2 8.2 4.1 2.3 1 1 1 2 2 2 0 RING-like zinc finger Prok-RING_4 PF14447.6 KII85962.1 - 0.29 11.0 9.2 0.11 12.4 4.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CLZ PF16526.5 KII85962.1 - 0.57 10.6 0.1 0.57 10.6 0.1 4.4 2 1 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tropomyosin_1 PF12718.7 KII85962.1 - 1.3 9.1 46.2 1.3 9.2 2.7 3.8 1 1 2 3 3 3 0 Tropomyosin like JSRP PF15312.6 KII85962.1 - 8.8 6.3 9.7 15 5.6 0.2 3.7 2 1 1 3 3 3 0 Junctional sarcoplasmic reticulum protein zf-C3HC4_3 PF13920.6 KII85963.1 - 5.2e-08 32.6 7.0 1.4e-07 31.3 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85963.1 - 2.1e-07 30.7 9.5 4.7e-07 29.6 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII85963.1 - 1.3e-05 25.4 10.1 1.3e-05 25.4 10.1 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 KII85963.1 - 2.1e-05 24.4 6.6 4.9e-05 23.2 6.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain HALZ PF02183.18 KII85963.1 - 4.4e-05 23.6 5.6 0.045 14.0 0.4 4.3 3 1 1 4 4 3 1 Homeobox associated leucine zipper DUF1664 PF07889.12 KII85963.1 - 7.9e-05 22.7 4.6 0.079 13.0 0.3 2.7 2 1 1 3 3 2 2 Protein of unknown function (DUF1664) zf-RING_UBOX PF13445.6 KII85963.1 - 0.00017 21.6 8.3 0.00017 21.6 8.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KII85963.1 - 0.00044 20.4 9.7 0.0011 19.1 9.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Nup54 PF13874.6 KII85963.1 - 0.00061 19.9 1.3 0.00061 19.9 1.3 3.2 1 1 1 2 2 1 1 Nucleoporin complex subunit 54 Sec34 PF04136.15 KII85963.1 - 0.0008 19.3 5.5 0.045 13.6 0.7 3.0 2 1 2 4 4 4 2 Sec34-like family Prok-RING_4 PF14447.6 KII85963.1 - 0.001 18.9 10.0 0.0022 17.8 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Laminin_II PF06009.12 KII85963.1 - 0.0015 18.6 1.6 0.0087 16.1 0.0 2.6 1 1 0 2 2 2 1 Laminin Domain II DUF16 PF01519.16 KII85963.1 - 0.0017 18.8 4.4 0.77 10.3 0.1 3.2 1 1 1 2 2 2 1 Protein of unknown function DUF16 DUF573 PF04504.14 KII85963.1 - 0.0018 18.9 4.9 2.2 9.0 0.3 3.6 1 1 2 3 3 3 1 Protein of unknown function, DUF573 T3SSipB PF16535.5 KII85963.1 - 0.0032 18.0 0.1 0.0032 18.0 0.1 2.7 1 1 2 3 3 2 1 Type III cell invasion protein SipB GAS PF13851.6 KII85963.1 - 0.0049 16.2 4.7 0.0049 16.2 4.7 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding zf-C3HC4_2 PF13923.6 KII85963.1 - 0.0092 15.8 10.0 0.022 14.6 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF812 PF05667.11 KII85963.1 - 0.014 14.3 20.6 0.04 12.8 20.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) RmuC PF02646.16 KII85963.1 - 0.015 14.4 9.3 0.016 14.4 0.3 2.9 1 1 1 3 3 3 0 RmuC family Dor1 PF04124.12 KII85963.1 - 0.016 13.9 0.3 0.036 12.8 0.3 1.6 1 0 0 1 1 1 0 Dor1-like family BLOC1_2 PF10046.9 KII85963.1 - 0.022 15.0 14.9 0.088 13.1 2.7 3.9 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 KII85963.1 - 0.054 13.2 17.7 4.8 6.8 13.8 3.1 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 EzrA PF06160.12 KII85963.1 - 0.06 11.5 11.4 0.046 11.9 7.0 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KII85963.1 - 0.14 11.1 21.4 0.16 10.8 11.4 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein Taxilin PF09728.9 KII85963.1 - 0.14 11.3 28.1 0.99 8.5 27.6 2.2 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF3450 PF11932.8 KII85963.1 - 0.14 11.4 12.3 0.036 13.4 0.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Lipocalin_2 PF08212.12 KII85963.1 - 0.15 11.9 2.4 0.12 12.3 0.6 1.7 2 0 0 2 2 1 0 Lipocalin-like domain DUF3782 PF12644.7 KII85963.1 - 0.16 12.1 0.1 0.16 12.1 0.1 4.1 2 1 1 3 3 2 0 Protein of unknown function (DUF3782) DUF948 PF06103.11 KII85963.1 - 0.18 12.0 0.1 0.99 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MapZ_EC1 PF18041.1 KII85963.1 - 0.2 11.9 1.2 79 3.5 0.1 3.2 1 1 1 3 3 3 0 MapZ extracellular domain 1 DUF5344 PF17279.2 KII85963.1 - 0.44 11.1 5.7 4.5 7.9 0.8 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5344) APG17 PF04108.12 KII85963.1 - 0.44 9.6 14.7 0.039 13.1 8.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 Atg14 PF10186.9 KII85963.1 - 0.59 9.2 10.4 1.5 7.8 1.1 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 KII85963.1 - 0.72 9.4 21.1 0.11 12.0 4.6 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.6 KII85963.1 - 0.77 8.3 13.0 1.6 7.3 11.4 1.8 1 1 0 1 1 1 0 AAA domain FapA PF03961.13 KII85963.1 - 0.78 8.3 9.9 0.39 9.2 1.5 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A CLZ PF16526.5 KII85963.1 - 0.89 10.0 23.4 3.9 7.9 1.7 4.6 3 2 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dynactin_p22 PF07426.11 KII85963.1 - 1.5 8.7 7.9 0.31 10.9 0.7 2.7 2 1 1 3 3 3 0 Dynactin subunit p22 DUF2959 PF11172.8 KII85963.1 - 1.5 8.9 16.6 0.75 9.9 2.5 3.1 1 1 0 3 3 3 0 Protein of unknown function (DUF2959) FliD_C PF07195.12 KII85963.1 - 1.8 7.9 3.2 4 6.8 1.3 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus YkyA PF10368.9 KII85963.1 - 2 8.0 24.9 0.037 13.7 14.2 2.4 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein AcylCoA_dehyd_C PF12186.8 KII85963.1 - 2.2 8.4 10.1 11 6.2 5.0 3.3 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Gp-FAR-1 PF05823.12 KII85963.1 - 2.4 8.5 4.7 63 3.9 0.6 3.2 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ZapB PF06005.12 KII85963.1 - 2.6 8.6 24.9 3.9 8.0 2.7 4.7 2 1 2 4 4 3 0 Cell division protein ZapB Cir_Bir_Yir PF06022.11 KII85963.1 - 2.7 7.4 6.8 0.56 9.7 1.9 1.9 1 1 1 2 2 2 0 Plasmodium variant antigen protein Cir/Yir/Bir Exonuc_VII_L PF02601.15 KII85963.1 - 2.9 7.4 17.2 4.8e+02 0.1 17.2 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit SLATT_5 PF18160.1 KII85963.1 - 3.4 6.9 7.9 30 3.8 4.5 2.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1910 PF08928.10 KII85963.1 - 3.9 7.5 7.4 6.6 6.8 1.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) SKA2 PF16740.5 KII85963.1 - 4.7 7.0 13.7 1.8 8.4 0.9 3.9 1 1 2 4 4 4 0 Spindle and kinetochore-associated protein 2 V_ATPase_I PF01496.19 KII85963.1 - 5.2 4.9 18.8 0.043 11.7 4.9 2.1 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 KII85963.1 - 5.6 7.8 21.7 1.4 9.7 9.9 3.4 2 2 1 3 3 3 0 Occludin homology domain Prefoldin_2 PF01920.20 KII85963.1 - 6 6.9 19.2 29 4.7 0.0 4.2 4 0 0 4 4 4 0 Prefoldin subunit Fmp27_WPPW PF10359.9 KII85963.1 - 6.2 5.6 17.6 0.016 14.1 2.6 2.3 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 KII85963.1 - 7.4 6.7 36.9 4.5 7.4 10.0 2.8 1 1 1 2 2 2 0 Tropomyosin like KxDL PF10241.9 KII85963.1 - 7.7 6.9 6.1 3.9 7.8 0.4 3.3 4 1 1 5 5 3 0 Uncharacterized conserved protein TMF_TATA_bd PF12325.8 KII85963.1 - 7.8 6.8 31.9 0.063 13.5 12.1 3.9 1 1 3 4 4 3 0 TATA element modulatory factor 1 TATA binding Sporozoite_P67 PF05642.11 KII85963.1 - 10 4.1 9.4 15 3.5 9.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C3HC4_3 PF13920.6 KII85964.1 - 9.9e-09 34.9 7.2 1.5e-08 34.3 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII85964.1 - 1.3e-08 34.5 7.9 2.5e-08 33.6 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII85964.1 - 4.6e-08 33.1 9.2 7.4e-08 32.4 9.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII85964.1 - 6.3e-08 32.8 8.5 1e-07 32.2 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII85964.1 - 1.7e-07 31.1 7.5 3.4e-07 30.2 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII85964.1 - 3.9e-07 29.8 8.4 6.2e-07 29.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85964.1 - 8.2e-06 25.7 7.6 1.3e-05 25.0 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII85964.1 - 1e-05 25.3 8.2 1.9e-05 24.4 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Filament PF00038.21 KII85964.1 - 0.018 14.6 1.4 0.018 14.6 1.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein zf-rbx1 PF12678.7 KII85964.1 - 0.039 14.3 6.0 0.11 12.8 6.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KII85964.1 - 0.056 13.3 6.0 0.12 12.3 6.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Tropomyosin PF00261.20 KII85964.1 - 0.14 11.5 12.2 0.41 10.0 12.3 1.6 1 1 0 1 1 1 0 Tropomyosin zf-RING_4 PF14570.6 KII85964.1 - 0.15 11.9 3.2 0.33 10.8 3.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.6 KII85964.1 - 0.22 11.3 2.1 1.2 9.0 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_10 PF16685.5 KII85964.1 - 0.45 10.7 4.8 0.88 9.8 4.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 SecD-TM1 PF13721.6 KII85964.1 - 0.52 10.8 3.1 2.4 8.7 2.1 2.1 1 1 1 2 2 2 0 SecD export protein N-terminal TM region TPR_MLP1_2 PF07926.12 KII85964.1 - 0.62 10.1 11.1 0.17 11.9 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CSN5_C PF18323.1 KII85964.1 - 0.84 10.6 6.5 5.4 8.0 6.5 2.3 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain HALZ PF02183.18 KII85964.1 - 1 9.6 8.7 3.4 7.9 0.1 3.0 3 1 1 4 4 2 0 Homeobox associated leucine zipper zinc_ribbon_4 PF13717.6 KII85964.1 - 1.4 8.9 3.8 19 5.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_11 PF17123.5 KII85964.1 - 2.9 7.7 8.9 3.9 7.3 7.9 1.8 2 0 0 2 2 1 0 RING-like zinc finger Tropomyosin_1 PF12718.7 KII85964.1 - 3.7 7.7 11.7 0.94 9.6 5.5 2.4 1 1 0 1 1 1 0 Tropomyosin like XhlA PF10779.9 KII85964.1 - 5.4 7.3 8.1 0.3 11.3 2.5 1.8 2 0 0 2 2 1 0 Haemolysin XhlA zf-RING_UBOX PF13445.6 KII85965.1 - 7.8e-06 25.8 12.3 1.6e-05 24.8 12.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII85965.1 - 1.4e-05 24.8 12.5 2.3e-05 24.2 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85965.1 - 5e-05 23.2 13.7 8.4e-05 22.4 13.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII85965.1 - 5.7e-05 22.9 14.7 0.00012 21.8 14.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII85965.1 - 0.00014 22.2 15.0 0.00022 21.5 15.0 1.4 1 0 0 1 1 1 1 Ring finger domain Exonuc_VII_L PF02601.15 KII85965.1 - 0.00024 20.8 3.4 0.0004 20.1 3.4 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit zf-C3HC4_4 PF15227.6 KII85965.1 - 0.00043 20.4 14.3 0.00077 19.6 14.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KII85965.1 - 0.0016 18.2 14.2 0.0031 17.4 14.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KII85965.1 - 0.0022 17.8 15.8 0.004 17.0 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.9 KII85965.1 - 0.033 13.3 10.7 0.077 12.1 10.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dor1 PF04124.12 KII85965.1 - 0.1 11.3 4.8 0.13 10.9 4.0 1.6 1 1 0 1 1 1 0 Dor1-like family MAD PF05557.13 KII85965.1 - 0.24 9.7 16.8 0.34 9.2 16.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein zf-RING_6 PF14835.6 KII85965.1 - 0.25 11.2 8.4 0.45 10.4 8.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Laminin_I PF06008.14 KII85965.1 - 0.38 10.4 15.7 0.09 12.5 7.7 2.1 1 1 0 2 2 2 0 Laminin Domain I Spectrin PF00435.21 KII85965.1 - 0.66 10.5 15.1 1 9.8 1.6 2.3 1 1 1 2 2 2 0 Spectrin repeat GAS PF13851.6 KII85965.1 - 0.69 9.2 17.0 1 8.6 17.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 KII85965.1 - 1.2 9.7 17.0 1 9.9 6.2 2.6 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4446 PF14584.6 KII85965.1 - 2.1 8.3 8.8 1.5 8.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.19 KII85965.1 - 5.3 4.8 13.5 18 3.1 13.5 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Nudix_N_2 PF14803.6 KII85965.1 - 5.9 6.9 8.9 2e+03 -1.2 8.8 3.0 1 1 0 1 1 1 0 Nudix N-terminal Spc7 PF08317.11 KII85965.1 - 8.8 5.1 18.8 6.9 5.5 3.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KII85965.1 - 9.3 6.3 17.0 1.3 9.1 9.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ARGLU PF15346.6 KII85965.1 - 9.5 6.1 25.3 0.42 10.5 9.4 2.4 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 DUF2333 PF10095.9 KII85965.1 - 10 5.1 8.2 17 4.3 5.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) GST_N_3 PF13417.6 KII85966.1 - 1.8e-11 44.3 0.3 4.2e-11 43.1 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII85966.1 - 5e-09 36.3 0.3 1.8e-08 34.6 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KII85966.1 - 0.0013 19.5 0.0 0.0024 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KII85966.1 - 0.029 14.4 0.3 0.052 13.6 0.3 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_88 PF07470.13 KII85967.1 - 3.5e-59 200.6 0.7 4.5e-59 200.3 0.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prominin PF05478.11 KII85969.1 - 0.28 9.1 11.4 0.17 9.8 3.0 2.3 1 1 1 2 2 2 0 Prominin NPV_P10 PF05531.12 KII85969.1 - 0.54 10.8 3.8 53 4.4 0.7 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4047 PF13256.6 KII85969.1 - 1.4 9.1 9.7 0.15 12.3 0.6 2.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4047) TACC_C PF05010.14 KII85969.1 - 1.7 8.4 26.9 0.017 15.0 14.4 2.7 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3584 PF12128.8 KII85969.1 - 3.2 5.2 22.3 4.7 4.6 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 KII85969.1 - 4.8 7.6 34.0 1.8 9.0 14.8 2.9 2 1 1 3 3 3 0 Fez1 HrpB7 PF09486.10 KII85969.1 - 6.3 7.2 33.4 1 9.7 13.9 4.0 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) ISG65-75 PF11727.8 KII85969.1 - 8.5 5.5 17.1 3.2 6.9 5.9 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein NMO PF03060.15 KII85970.1 - 6.8e-49 167.0 2.7 1e-48 166.4 2.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KII85970.1 - 2.6e-07 30.0 0.2 5.2e-06 25.7 0.2 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.15 KII85970.1 - 0.024 14.5 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FMN_dh PF01070.18 KII85970.1 - 0.034 13.2 3.0 0.051 12.6 3.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pantoate_transf PF02548.15 KII85970.1 - 0.64 9.4 2.8 6.3 6.1 0.2 2.6 3 0 0 3 3 3 0 Ketopantoate hydroxymethyltransferase Glyco_hydro_12 PF01670.16 KII85971.1 - 4.3e-38 131.4 10.8 5.1e-38 131.2 10.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 HAUS-augmin3 PF14932.6 KII85972.1 - 0.011 15.4 2.0 0.012 15.2 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 KII85972.1 - 0.014 14.5 5.2 0.016 14.3 5.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-Q PF13094.6 KII85972.1 - 0.023 14.9 8.2 0.03 14.5 8.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Leu_zip PF15294.6 KII85972.1 - 0.024 14.2 2.3 0.028 14.0 2.3 1.1 1 0 0 1 1 1 0 Leucine zipper Tho2 PF11262.8 KII85972.1 - 0.027 13.7 0.5 0.026 13.7 0.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 KII85972.1 - 0.06 11.9 4.0 0.063 11.8 4.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KII85972.1 - 0.067 13.6 7.4 0.067 13.6 7.4 2.0 1 1 0 1 1 1 0 Cell division protein ZapB BRO1 PF03097.18 KII85972.1 - 0.11 11.3 2.6 0.12 11.1 2.6 1.1 1 0 0 1 1 1 0 BRO1-like domain ADIP PF11559.8 KII85972.1 - 0.15 12.1 10.4 0.2 11.7 10.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KII85972.1 - 0.16 12.3 1.2 0.28 11.5 1.0 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family OmpH PF03938.14 KII85972.1 - 0.27 11.5 8.3 0.35 11.2 8.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 KII85972.1 - 0.42 11.3 8.6 0.62 10.7 8.6 1.2 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 KII85972.1 - 1 9.2 12.2 0.082 12.7 6.2 1.8 1 1 1 2 2 2 0 Septum formation initiator TMPIT PF07851.13 KII85972.1 - 1.5 8.0 3.3 1.9 7.7 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4337 PF14235.6 KII85972.1 - 2.7 8.1 6.8 3.7 7.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-RING_UBOX PF13445.6 KII85974.1 - 2.5e-10 40.2 14.6 1.2e-08 34.9 9.5 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII85974.1 - 6.7e-10 38.7 13.0 1.2e-09 37.9 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII85974.1 - 2.5e-08 33.6 14.7 4.3e-08 32.9 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII85974.1 - 6.8e-08 32.7 14.7 1.5e-07 31.6 14.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII85974.1 - 1.5e-07 31.2 13.8 6.1e-07 29.2 13.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII85974.1 - 8e-07 28.9 13.9 1.3e-06 28.3 13.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KII85974.1 - 9.5e-07 28.9 12.2 2.1e-06 27.8 12.3 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KII85974.1 - 3.8e-06 26.7 11.9 7.2e-06 25.8 11.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KII85974.1 - 0.004 16.9 9.5 0.01 15.6 9.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 KII85974.1 - 0.032 13.6 0.2 0.032 13.6 0.2 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger zf-ANAPC11 PF12861.7 KII85974.1 - 0.036 14.1 5.2 0.058 13.5 5.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sas6_CC PF18594.1 KII85974.1 - 0.069 12.9 1.2 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Baculo_IE-1 PF05290.11 KII85974.1 - 0.11 12.5 7.4 0.18 11.7 7.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KII85974.1 - 0.14 12.3 7.9 0.32 11.2 7.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 KII85974.1 - 0.48 10.8 11.7 1.4 9.2 11.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KII85974.1 - 0.78 9.5 13.7 0.71 9.7 10.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 KII85974.1 - 1.6 8.6 9.2 4.2 7.3 9.2 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein F-box PF00646.33 KII85975.1 - 0.043 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain BTB PF00651.31 KII85977.1 - 9.7e-05 22.6 0.0 0.00029 21.1 0.0 1.7 1 1 1 2 2 2 1 BTB/POZ domain Ribosomal_L5_C PF00673.21 KII85978.1 - 1.2e-20 73.5 0.0 1.8e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KII85978.1 - 4.9e-19 68.4 0.1 1.1e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 GPI-anchored PF10342.9 KII85980.1 - 2.6e-08 34.5 2.6 2.6e-08 34.5 2.6 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 KII85980.1 - 0.26 10.4 17.7 0.3 10.2 17.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Stanniocalcin PF03298.13 KII85981.1 - 6e-08 32.3 0.0 7e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Stanniocalcin family IBV_3C PF03620.13 KII85981.1 - 0.049 14.1 0.2 0.094 13.2 0.2 1.4 1 0 0 1 1 1 0 IBV 3C protein AA_permease_2 PF13520.6 KII85982.1 - 5.9e-56 190.1 47.9 6.9e-56 189.9 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII85982.1 - 4.7e-16 58.5 41.9 6.6e-16 58.0 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2754 PF10953.8 KII85982.1 - 0.17 12.2 0.3 0.17 12.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) COesterase PF00135.28 KII85983.1 - 8.3e-54 183.3 0.0 1.5e-53 182.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII85983.1 - 1.6e-07 31.4 0.3 9.2e-07 28.9 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold MatE PF01554.18 KII85984.1 - 1.7e-42 144.8 23.9 1.6e-26 92.9 8.0 2.7 3 0 0 3 3 3 2 MatE UPF0242 PF06785.11 KII85984.1 - 0.0035 17.5 0.0 0.0035 17.5 0.0 2.3 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus MatE PF01554.18 KII85985.1 - 6.8e-06 25.8 0.7 8.8e-06 25.5 0.7 1.1 1 0 0 1 1 1 1 MatE Arginase PF00491.21 KII85986.1 - 5.5e-85 285.3 0.0 8.4e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KII85986.1 - 0.069 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Sel_put PF04328.13 KII85986.1 - 0.76 9.9 1.8 2 8.5 1.6 1.7 2 0 0 2 2 2 0 Selenoprotein, putative AA_permease_2 PF13520.6 KII85987.1 - 5.6e-58 196.8 52.2 7.2e-58 196.4 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII85987.1 - 1e-16 60.7 49.2 7.9e-16 57.7 48.9 2.2 1 1 0 1 1 1 1 Amino acid permease Patatin PF01734.22 KII85987.1 - 0.092 12.9 0.8 0.16 12.1 0.8 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase Polysacc_deac_1 PF01522.21 KII85988.1 - 2.1e-11 43.8 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KII85988.1 - 2.7e-07 30.4 0.1 1.6e-06 28.0 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) La_HTH_kDCL PF18177.1 KII85988.1 - 0.11 12.9 0.0 0.47 10.8 0.0 2.0 1 1 0 1 1 1 0 La HTH in kinetoplastid DICER domain DUF2194 PF09960.9 KII85988.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) COesterase PF00135.28 KII85989.1 - 3.1e-48 164.9 0.0 3.8e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII85989.1 - 7.3e-07 29.3 0.3 1.7e-06 28.1 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold GDPD PF03009.17 KII85990.1 - 0.094 12.4 0.0 2.4 7.8 0.0 2.3 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family STT3 PF02516.14 KII85991.1 - 3.9e-148 494.4 35.0 6.3e-142 473.9 31.6 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ADIP PF11559.8 KII85992.1 - 4.1e-26 91.9 7.1 4.1e-26 91.9 7.1 3.7 3 1 0 3 3 3 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KII85992.1 - 0.00097 19.2 8.3 0.00097 19.2 8.3 3.9 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KII85992.1 - 0.18 11.1 17.9 0.56 9.5 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Goodbye PF17109.5 KII85992.1 - 0.26 11.8 3.9 5 7.6 0.0 3.5 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain PcfK PF14058.6 KII85992.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.9 3 0 0 3 3 3 0 PcfK-like protein Spc42p PF11544.8 KII85992.1 - 0.74 9.9 0.0 0.74 9.9 0.0 3.2 4 0 0 4 4 4 0 Spindle pole body component Spc42p Halogen_Hydrol PF10112.9 KII85992.1 - 0.86 9.6 6.3 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Cob_adeno_trans PF01923.18 KII85992.1 - 0.91 9.6 13.5 2.7 8.1 4.8 4.0 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Golgin_A5 PF09787.9 KII85992.1 - 1.9 7.9 22.5 0.013 14.9 6.2 3.2 3 1 1 4 4 4 0 Golgin subfamily A member 5 Filament PF00038.21 KII85992.1 - 4.5 6.8 22.4 0.27 10.8 9.9 2.9 2 2 0 2 2 2 0 Intermediate filament protein Atg14 PF10186.9 KII85992.1 - 5.4 6.0 16.7 3.6 6.6 7.3 2.6 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 KII85992.1 - 6.4 7.1 24.6 0.059 13.7 3.2 3.8 2 2 2 4 4 4 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 KII85992.1 - 8.7 6.9 31.1 0.32 11.5 6.1 4.0 3 1 1 4 4 4 0 Apg6 coiled-coil region UCH PF00443.29 KII85993.1 - 5.7e-64 216.1 0.0 1.1e-63 215.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII85993.1 - 1e-18 68.0 0.0 2.2e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 KII85993.1 - 0.0031 17.2 0.2 0.0068 16.1 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Syntaxin PF00804.25 KII85993.1 - 0.038 13.7 0.6 0.074 12.7 0.6 1.5 1 0 0 1 1 1 0 Syntaxin MIT PF04212.18 KII85993.1 - 0.16 12.1 0.6 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain zf-HC5HC2H_2 PF13832.6 KII85994.1 - 5.1e-19 68.5 23.5 1.8e-18 66.7 0.6 4.3 3 1 1 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KII85994.1 - 5.3e-15 55.4 0.0 1.9e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H PF13771.6 KII85994.1 - 6.2e-14 52.0 26.5 1.3e-13 51.0 1.1 4.7 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 KII85994.1 - 4.1e-12 45.8 55.3 1.4e-08 34.5 11.7 6.0 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 KII85994.1 - 2.2e-05 23.9 3.9 2.2e-05 23.9 3.9 5.9 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.31 KII85994.1 - 0.023 14.9 0.1 1.1 9.6 0.1 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain ELM2 PF01448.24 KII85994.1 - 0.038 14.8 0.0 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 ELM2 domain DUF1104 PF06518.11 KII85994.1 - 0.12 12.7 0.5 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) HATPase_c PF02518.26 KII85995.1 - 6.3e-21 75.0 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KII85995.1 - 6.5e-16 58.5 0.2 2e-14 53.7 0.1 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KII85995.1 - 2.2e-07 30.8 0.1 5.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ran_BP1 PF00638.18 KII85996.1 - 1.5e-16 60.7 0.1 2.4e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 RanBP1 domain Glycos_transf_2 PF00535.26 KII85997.1 - 9.5e-24 84.1 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KII85997.1 - 1.4e-13 51.3 0.0 2.1e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KII85997.1 - 0.0069 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Thi4 PF01946.17 KII85997.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Glyco_tranf_2_4 PF13704.6 KII85997.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Lipase_3 PF01764.25 KII85999.1 - 3.2e-21 75.7 0.0 4.3e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 KII85999.1 - 0.0055 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KII85999.1 - 0.016 15.9 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 KII85999.1 - 0.082 12.2 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Thioesterase PF00975.20 KII85999.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KII86000.1 - 8.3e-22 77.6 0.1 1.2e-21 77.1 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 KII86000.1 - 0.0059 16.2 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 KII86000.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 KII86000.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KII86000.1 - 0.03 14.9 0.2 0.051 14.2 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Herpes_UL35 PF04496.12 KII86000.1 - 0.096 13.0 0.5 0.29 11.4 0.5 1.8 1 0 0 1 1 1 0 Herpesvirus UL35 family DUF2974 PF11187.8 KII86000.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-MYND PF01753.18 KII86002.1 - 4.4e-08 33.1 11.2 4.4e-08 33.1 11.2 2.2 2 0 0 2 2 2 1 MYND finger SEC-C PF02810.15 KII86002.1 - 8e-07 28.9 9.2 0.01 15.8 4.0 2.6 2 0 0 2 2 2 2 SEC-C motif Ank PF00023.30 KII86002.1 - 9.4e-05 22.7 1.0 0.17 12.4 0.4 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KII86002.1 - 0.00022 21.7 0.2 0.0034 18.0 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII86002.1 - 0.00038 20.7 5.6 0.021 15.3 0.2 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KII86002.1 - 0.0066 16.7 1.1 1.9 8.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-C6H2 PF15801.5 KII86002.1 - 0.015 15.6 9.3 0.048 14.0 9.3 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ank_4 PF13637.6 KII86002.1 - 0.035 14.7 1.3 2.2 9.0 0.4 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ran_BP1 PF00638.18 KII86003.1 - 3.4e-05 24.1 0.0 5.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain DEC-1_N PF04625.13 KII86003.1 - 2.8 6.9 8.3 4.7 6.1 8.3 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Thioredoxin PF00085.20 KII86004.1 - 1e-19 70.4 0.0 3.9e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KII86004.1 - 0.0036 17.7 0.3 0.011 16.2 0.0 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KII86004.1 - 0.024 14.8 0.0 0.091 12.9 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KII86004.1 - 0.18 12.2 0.0 16 5.9 0.0 2.7 2 1 0 3 3 3 0 Thioredoxin-like zf-MYND PF01753.18 KII86005.1 - 1.1e-08 35.0 9.3 1.1e-08 35.0 9.3 2.1 2 0 0 2 2 2 1 MYND finger Ank PF00023.30 KII86005.1 - 1.1e-05 25.6 1.1 0.0042 17.5 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat SEC-C PF02810.15 KII86005.1 - 1.9e-05 24.4 11.2 0.00019 21.3 2.9 2.7 2 0 0 2 2 2 2 SEC-C motif Ank_2 PF12796.7 KII86005.1 - 3.3e-05 24.4 0.0 0.0002 21.9 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII86005.1 - 0.00032 20.9 2.6 0.077 13.6 0.1 4.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KII86005.1 - 0.00072 20.1 1.0 0.36 11.5 0.2 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 KII86006.1 - 4.8e-07 29.8 10.0 4.8e-07 29.8 10.0 2.0 2 0 0 2 2 2 1 MYND finger SEC-C PF02810.15 KII86006.1 - 1.1e-05 25.2 10.9 0.016 15.1 5.4 2.5 2 0 0 2 2 2 2 SEC-C motif Ank_3 PF13606.6 KII86006.1 - 0.00015 21.9 1.3 0.033 14.7 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 KII86006.1 - 0.012 16.1 0.2 0.14 12.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-C6H2 PF15801.5 KII86006.1 - 0.056 13.8 6.1 0.16 12.3 6.1 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ank_5 PF13857.6 KII86006.1 - 0.065 13.6 0.5 0.24 11.8 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 KII86006.1 - 0.16 12.6 0.9 5.2 7.8 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Med13_C PF06333.12 KII86007.1 - 3.1 7.0 10.0 3.8 6.7 10.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Phage_GPD PF05954.11 KII86007.1 - 7.2 5.8 6.0 11 5.2 6.0 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Rxt3 PF08642.10 KII86008.1 - 0.00036 21.3 0.2 0.0014 19.4 0.0 2.1 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Pkinase PF00069.25 KII86009.1 - 2.5e-62 210.7 0.0 5.7e-62 209.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86009.1 - 1.2e-37 129.6 0.0 2.9e-36 125.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase SYCE1 PF15233.6 KII86009.1 - 0.00063 19.8 11.1 0.0014 18.7 11.1 1.6 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Kinase-like PF14531.6 KII86009.1 - 0.00089 18.7 0.0 0.00089 18.7 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KII86009.1 - 0.0034 16.2 0.1 0.013 14.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KII86009.1 - 0.07 12.1 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Macoilin PF09726.9 KII86009.1 - 0.17 10.4 6.7 0.23 10.0 6.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF4778 PF16008.5 KII86009.1 - 0.24 11.4 6.3 0.46 10.5 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) APH PF01636.23 KII86009.1 - 0.32 10.9 13.7 0.037 14.0 1.0 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family YabA PF06156.13 KII86009.1 - 2.4 8.9 6.6 66 4.2 0.0 3.2 1 1 0 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 KII86009.1 - 3.2 6.7 11.5 6.9 5.7 11.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KII86009.1 - 9.1 4.7 15.3 14 4.0 15.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNase_H2_suC PF08615.11 KII86010.1 - 9.3e-18 64.8 0.0 1.3e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SPESP1 PF15754.5 KII86010.1 - 0.58 9.3 2.6 0.92 8.6 2.6 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 zf-MYND PF01753.18 KII86011.1 - 6.1e-09 35.8 9.9 1.7e-08 34.4 9.9 1.8 1 0 0 1 1 1 1 MYND finger Ank PF00023.30 KII86011.1 - 1.6e-07 31.5 0.4 0.00021 21.6 0.2 3.6 2 1 1 3 3 3 1 Ankyrin repeat SEC-C PF02810.15 KII86011.1 - 3.4e-07 30.1 11.9 0.0011 18.8 4.8 2.9 2 0 0 2 2 2 2 SEC-C motif Ank_2 PF12796.7 KII86011.1 - 1.2e-06 29.0 0.0 1.8e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII86011.1 - 8.4e-06 25.8 2.0 0.019 15.5 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KII86011.1 - 0.00032 21.2 0.3 0.0063 17.1 0.1 3.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII86011.1 - 0.00057 20.1 0.0 0.28 11.5 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) zf-C6H2 PF15801.5 KII86011.1 - 0.068 13.5 5.4 0.18 12.2 5.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII86013.1 - 2e-07 31.0 8.8 3.4e-07 30.2 8.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII86013.1 - 0.075 13.4 5.6 0.13 12.6 5.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SEC-C PF02810.15 KII86014.1 - 1.8e-09 37.3 5.6 1.1e-05 25.2 1.7 2.7 2 0 0 2 2 2 2 SEC-C motif zf-MYND PF01753.18 KII86014.1 - 4.3e-08 33.1 8.0 1.1e-07 31.9 8.0 1.7 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 KII86014.1 - 9.4e-05 22.9 0.0 0.0006 20.3 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KII86014.1 - 0.00033 20.9 0.1 0.032 14.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KII86014.1 - 0.0049 17.4 0.0 0.16 12.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) SH3_9 PF14604.6 KII86015.1 - 1.3e-28 98.6 2.0 9.1e-15 54.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KII86015.1 - 6.4e-26 89.7 2.3 3.1e-12 45.9 0.2 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KII86015.1 - 1e-22 80.2 0.0 1.7e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KII86015.1 - 5.2e-17 61.3 0.0 7.8e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Ytp1 PF10355.9 KII86016.1 - 5.5e-55 186.5 19.2 6e-54 183.1 15.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KII86016.1 - 3.8e-29 100.5 1.8 3.8e-29 100.5 1.8 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KII86016.1 - 0.0023 18.0 4.9 0.0023 18.0 4.9 3.6 3 2 1 4 4 4 1 Eukaryotic cytochrome b561 DUF4225 PF13988.6 KII86016.1 - 0.16 11.5 0.2 0.46 10.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) TMEM100 PF16311.5 KII86016.1 - 0.17 11.5 0.4 0.48 10.0 0.2 1.8 1 1 0 1 1 1 0 Transmembrane protein 100 zf-C2H2 PF00096.26 KII86017.1 - 0.23 12.0 8.6 1.9 9.1 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type KH_1 PF00013.29 KII86018.1 - 1.2e-05 25.1 0.2 3.8e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 KH domain Mito_fiss_reg PF05308.11 KII86018.1 - 0.036 14.2 5.6 0.059 13.4 5.6 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box PF00646.33 KII86019.1 - 4.7e-06 26.3 0.9 4.7e-06 26.3 0.9 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII86019.1 - 0.0015 18.4 0.5 0.0028 17.5 0.5 1.5 1 0 0 1 1 1 1 F-box-like UBX PF00789.20 KII86020.1 - 8.1e-12 45.2 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 KII86020.1 - 0.00024 20.9 0.0 0.00083 19.2 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Utp11 PF03998.13 KII86020.1 - 0.026 14.5 12.3 0.036 14.0 12.3 1.2 1 0 0 1 1 1 0 Utp11 protein zf-C2H2_2 PF12756.7 KII86020.1 - 0.047 14.0 0.3 0.12 12.7 0.2 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_10 PF10058.9 KII86020.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Atg14 PF10186.9 KII86020.1 - 1.6 7.7 9.8 2.3 7.2 9.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M55 PF04951.13 KII86020.1 - 3.9 6.8 8.0 8.9 5.6 7.8 1.6 2 0 0 2 2 2 0 D-aminopeptidase NAD_binding_10 PF13460.6 KII86021.1 - 1.2e-09 38.3 0.5 1.6e-09 37.9 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KII86021.1 - 0.00048 20.5 0.1 0.0012 19.3 0.1 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KII86021.1 - 0.0014 18.1 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KII86021.1 - 0.0024 17.5 1.7 0.015 14.9 1.7 2.0 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 KII86021.1 - 0.11 12.7 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SKG6 PF08693.10 KII86022.1 - 3.9e-05 23.0 0.1 0.00012 21.4 0.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 KII86022.1 - 0.0046 17.1 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Spc7 PF08317.11 KII86025.1 - 0.14 11.0 1.1 0.22 10.3 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein NAD_binding_10 PF13460.6 KII86026.1 - 6.3e-09 36.0 0.0 8.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII86026.1 - 3.4e-05 23.4 0.1 5.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KII86026.1 - 0.00084 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 KII86026.1 - 0.0049 17.3 0.2 0.013 15.9 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KII86026.1 - 0.17 11.4 0.7 0.32 10.5 0.2 1.7 2 0 0 2 2 2 0 NmrA-like family Mito_carr PF00153.27 KII86027.1 - 0.082 12.8 1.0 9.7 6.2 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial carrier protein Med15 PF09606.10 KII86027.1 - 0.24 10.0 1.4 0.29 9.8 1.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phos_pyr_kin PF08543.12 KII86029.1 - 2.3e-11 43.5 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KII86029.1 - 1.3e-06 27.9 0.0 6.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Actin PF00022.19 KII86030.1 - 1.5e-116 389.3 0.0 6.8e-116 387.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KII86030.1 - 0.00044 19.2 0.0 0.00067 18.6 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein START PF01852.19 KII86031.1 - 1.1e-15 57.7 0.0 2.2e-08 33.8 0.0 3.3 3 0 0 3 3 3 2 START domain LisH PF08513.11 KII86032.1 - 0.00042 20.2 0.1 0.00081 19.3 0.1 1.5 1 0 0 1 1 1 1 LisH FCP1_C PF09309.10 KII86032.1 - 0.52 10.2 15.0 1.3 8.9 15.0 1.6 1 0 0 1 1 1 0 FCP1, C-terminal AUX_IAA PF02309.16 KII86032.1 - 3.4 7.4 8.6 5.8 6.7 7.7 1.8 2 0 0 2 2 2 0 AUX/IAA family SKG6 PF08693.10 KII86033.1 - 0.0005 19.4 7.9 0.0005 19.4 7.9 2.3 2 1 0 2 2 2 1 Transmembrane alpha-helix domain PorA PF11271.8 KII86033.1 - 0.0037 16.6 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 Porin PorA GT87 PF09594.10 KII86033.1 - 0.0057 16.4 0.9 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 87 EphA2_TM PF14575.6 KII86033.1 - 0.07 14.0 0.0 0.17 12.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5337 PF17272.2 KII86033.1 - 0.17 11.7 0.7 0.39 10.6 0.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF3852 PF12963.7 KII86033.1 - 0.26 11.7 1.2 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) 3Beta_HSD PF01073.19 KII86034.1 - 1.6e-28 99.5 0.0 1.6e-27 96.2 0.0 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII86034.1 - 5.3e-16 58.8 0.0 1.4e-15 57.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII86034.1 - 5.7e-14 51.9 0.0 3.9e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KII86034.1 - 3.8e-07 29.8 0.0 1.7e-06 27.7 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KII86034.1 - 3.4e-05 23.8 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KII86034.1 - 0.0017 17.6 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KII86034.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KII86034.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HSF_DNA-bind PF00447.17 KII86035.1 - 7.3e-30 103.4 0.6 1e-29 103.0 0.6 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4606 PF15379.6 KII86035.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) KIAA1430 PF13879.6 KII86036.1 - 0.085 13.6 0.0 0.094 13.5 0.0 1.2 1 0 0 1 1 1 0 KIAA1430 homologue Spectrin PF00435.21 KII86036.1 - 0.091 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Spectrin repeat NdhO PF11910.8 KII86036.1 - 0.2 11.8 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Mt_ATP-synt_B PF05405.14 KII86037.1 - 4.9e-44 149.8 8.1 6e-44 149.5 8.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 KII86037.1 - 0.0079 16.3 1.0 1 9.4 0.3 2.6 1 1 1 3 3 3 2 Domain of Unknown Function (DUF1539) Peptidase_C10 PF01640.17 KII86037.1 - 0.098 13.0 0.1 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 Peptidase C10 family DUF5623 PF18536.1 KII86037.1 - 0.22 11.8 1.7 0.29 11.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) DUF4407 PF14362.6 KII86037.1 - 9.5 5.5 11.7 0.53 9.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Dynamin_M PF01031.20 KII86038.1 - 4.6e-109 364.0 0.0 1e-108 362.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KII86038.1 - 2e-55 187.4 0.0 4.3e-55 186.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KII86038.1 - 2.5e-29 101.3 0.7 6.7e-29 99.9 0.2 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII86038.1 - 0.00016 21.7 0.1 0.00071 19.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KII86038.1 - 0.055 12.8 0.1 7.5 5.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family TipAS PF07739.13 KII86038.1 - 0.15 12.6 0.3 0.9 10.1 0.0 2.4 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Condensin2nSMC PF12422.8 KII86038.1 - 0.15 12.3 0.0 0.69 10.1 0.0 2.1 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit BCS1_N PF08740.11 KII86040.1 - 4.7e-45 153.9 1.6 4.7e-45 153.9 1.6 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KII86040.1 - 2.7e-14 53.7 0.0 3e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KII86040.1 - 0.00087 19.5 0.4 0.0028 17.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII86040.1 - 0.0017 18.7 0.2 0.0017 18.7 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KII86040.1 - 0.0051 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase YlbE PF14003.6 KII86040.1 - 0.038 14.4 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 YlbE-like protein ATPase PF06745.13 KII86040.1 - 0.058 12.7 0.0 0.38 10.1 0.0 2.3 3 0 0 3 3 3 0 KaiC NACHT PF05729.12 KII86040.1 - 0.072 13.0 0.1 0.24 11.3 0.1 1.9 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 KII86040.1 - 0.074 12.2 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KII86040.1 - 0.095 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KII86040.1 - 0.12 12.1 2.7 3.8 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KII86040.1 - 0.15 12.1 0.1 0.39 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KII86040.1 - 0.15 12.6 2.0 0.19 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KII86040.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KII86040.1 - 0.38 11.2 5.9 18 5.8 5.3 2.3 2 0 0 2 2 2 0 AAA domain DUF1682 PF07946.14 KII86040.1 - 1.6 7.9 9.0 2.1 7.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAA_17 PF13207.6 KII86040.1 - 2.1 8.8 5.7 1.2 9.6 0.1 2.7 3 0 0 3 3 2 0 AAA domain SYS1 PF09801.9 KII86042.1 - 3.2e-25 88.9 1.7 1.3e-17 64.2 1.1 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.21 KII86043.1 - 2.7e-95 319.2 0.1 3.6e-95 318.7 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KII86043.1 - 2.6e-48 164.3 1.0 4.6e-48 163.5 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KII86043.1 - 5.2e-07 29.5 1.9 2.8e-06 27.1 1.9 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KII86043.1 - 0.00055 19.7 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KII86043.1 - 0.0063 15.2 0.1 0.12 11.0 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 KII86043.1 - 0.045 13.7 1.8 10 6.2 0.1 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CSD2 PF17876.1 KII86043.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Cold shock domain Nro1 PF12753.7 KII86044.1 - 0.0031 16.5 0.2 1.5 7.7 0.0 2.5 2 1 0 2 2 2 2 Nuclear pore complex subunit Nro1 Mito_carr PF00153.27 KII86045.1 - 5.9e-54 180.0 3.5 5.3e-18 64.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.18 KII86046.1 - 2.7e-10 40.1 0.0 2.6e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.28 KII86049.1 - 1.2e-27 96.6 0.0 2.7e-26 92.1 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme TPR_1 PF00515.28 KII86051.1 - 4.4e-28 95.9 0.0 8.5e-05 22.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KII86051.1 - 1.2e-27 93.7 0.5 6.5e-05 22.7 0.1 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.31 KII86051.1 - 5.3e-20 71.3 0.1 9.9e-20 70.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.6 KII86051.1 - 1.8e-18 65.9 2.3 3.1e-08 33.2 0.0 5.5 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.6 KII86051.1 - 9.5e-18 64.6 13.3 7.6e-05 23.3 1.4 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KII86051.1 - 5.7e-17 61.6 12.9 3.5e-07 30.3 0.1 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII86051.1 - 8.7e-16 58.0 11.3 1.7e-05 25.0 0.1 6.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII86051.1 - 8.5e-12 45.4 10.3 0.0017 18.8 0.2 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII86051.1 - 6.2e-10 39.1 17.2 0.18 12.7 0.2 7.3 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII86051.1 - 6e-06 26.3 0.6 1.9 9.1 0.0 5.4 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII86051.1 - 6.6e-06 26.3 0.5 1.5 9.1 0.0 5.0 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KII86051.1 - 2.2e-05 24.3 0.2 8 7.0 0.0 5.4 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII86051.1 - 2.9e-05 23.8 1.6 0.44 10.7 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KII86051.1 - 4.2e-05 22.9 2.9 0.0058 15.9 0.2 4.0 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII86051.1 - 8.6e-05 22.9 1.5 5.2 7.9 0.0 5.0 6 1 1 7 7 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KII86051.1 - 0.00013 21.4 0.1 3.6 7.1 0.0 4.5 5 0 0 5 5 5 1 SHNi-TPR Fis1_TPR_C PF14853.6 KII86051.1 - 0.00015 21.8 0.6 0.11 12.6 0.1 3.2 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KII86051.1 - 0.00021 21.3 1.2 4.1 7.6 0.0 4.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 KII86051.1 - 0.0053 16.2 0.2 0.54 9.6 0.0 3.0 4 0 0 4 4 4 1 Coatomer epsilon subunit ANAPC5 PF12862.7 KII86051.1 - 0.0057 16.7 0.1 1 9.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 KII86051.1 - 0.0091 16.5 3.6 19 6.2 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPM_phosphatase PF04536.14 KII86051.1 - 0.025 14.7 0.2 3.9 7.7 0.0 2.9 2 0 0 2 2 2 0 TPM domain Sec8_exocyst PF04048.14 KII86051.1 - 0.031 14.2 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TPR_21 PF09976.9 KII86051.1 - 0.04 13.6 9.2 0.88 9.2 0.0 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain GSK-3_bind PF05350.12 KII86051.1 - 0.086 12.1 3.8 0.13 11.6 3.1 1.6 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding HemY_N PF07219.13 KII86051.1 - 0.36 11.0 11.3 19 5.5 0.2 4.9 3 1 2 5 5 5 0 HemY protein N-terminus TPR_10 PF13374.6 KII86051.1 - 0.67 9.9 8.3 19 5.3 0.1 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat YfdX PF10938.8 KII86051.1 - 4.6 7.2 6.8 3 7.8 0.6 2.8 3 1 0 3 3 2 0 YfdX protein WD40 PF00400.32 KII86052.1 - 1.9e-32 110.8 25.7 1.6e-07 31.9 0.2 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII86052.1 - 1.2e-11 44.8 1.5 4.9e-05 23.5 0.0 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KII86052.1 - 3.1e-09 36.6 5.2 3.1e-09 36.6 5.2 2.1 2 0 0 2 2 2 1 F-box-like WD40_like PF17005.5 KII86052.1 - 4e-06 26.4 0.0 0.05 12.9 0.0 3.2 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 KII86052.1 - 2.2e-05 23.3 1.5 1.5 7.4 0.0 4.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DNA_pol_delta_4 PF04081.13 KII86053.1 - 1.2e-30 106.5 1.6 3.8e-30 104.9 1.6 1.9 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 WLM PF08325.10 KII86054.1 - 1.4e-31 110.1 0.0 2.9e-31 109.0 0.0 1.5 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 KII86054.1 - 2e-08 33.8 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KII86054.1 - 0.036 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KII86054.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain zf-HC5HC2H_2 PF13832.6 KII86055.1 - 9.8e-34 115.8 9.9 6.5e-33 113.2 5.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KII86055.1 - 3.9e-25 87.9 10.6 1.3e-24 86.3 3.2 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 KII86055.1 - 5.4e-23 82.1 0.4 1.8e-22 80.4 0.4 1.9 1 0 0 1 1 1 1 Enhancer of polycomb-like Bromodomain PF00439.25 KII86055.1 - 3.6e-18 65.4 0.2 8e-18 64.3 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KII86055.1 - 8.3e-15 54.1 3.0 8.3e-15 54.1 3.0 3.0 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.17 KII86055.1 - 1.3e-14 54.3 0.0 3.7e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 KII86055.1 - 1.2e-10 41.1 5.5 1.2e-10 41.1 5.5 2.7 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 KII86055.1 - 0.0035 17.0 0.7 0.0035 17.0 0.7 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KII86055.1 - 0.015 15.2 0.4 0.015 15.2 0.4 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KII86055.1 - 2.2 8.6 14.2 0.29 11.5 1.2 2.9 3 0 0 3 3 3 0 C1 domain CBM_1 PF00734.18 KII86056.1 - 2.5e-10 40.1 6.5 2.5e-10 40.1 6.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KII86056.1 - 2.4e-07 30.9 0.0 3.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII86056.1 - 6e-07 30.0 0.4 1e-06 29.3 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RNA_pol_Rbc25 PF08292.12 KII86057.1 - 5.7e-31 107.4 0.0 2.1e-30 105.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KII86057.1 - 3.1e-21 75.5 0.1 5e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Amidase PF01425.21 KII86058.1 - 9.8e-118 393.9 1.6 1.2e-117 393.7 1.6 1.0 1 0 0 1 1 1 1 Amidase Lipase_GDSL PF00657.22 KII86059.1 - 0.0016 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII86059.1 - 0.0037 17.7 7.9 0.0055 17.1 7.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Mito_carr PF00153.27 KII86060.1 - 2.7e-64 213.1 1.4 3e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KII86061.1 - 1.1e-18 67.3 0.4 3.8e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII86061.1 - 0.00052 20.3 0.0 0.025 14.9 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpc4 PF05132.14 KII86061.1 - 0.021 15.3 1.7 1 9.8 0.0 2.8 2 1 0 2 2 2 0 RNA polymerase III RPC4 WD40 PF00400.32 KII86062.1 - 0.00033 21.4 0.1 1.4 9.9 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Roughex PF06020.11 KII86062.1 - 0.027 13.6 10.3 0.031 13.4 10.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 KII86062.1 - 0.36 9.1 7.9 0.35 9.1 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KII86062.1 - 0.55 9.8 11.4 0.62 9.6 11.4 1.1 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KII86062.1 - 3.7 6.8 16.5 4.1 6.6 16.5 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 KII86062.1 - 5.1 6.4 9.7 6.1 6.2 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 KII86062.1 - 7.2 6.8 23.4 11 6.3 23.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1604 PF07713.13 KII86063.1 - 4.5e-38 129.0 1.1 4.5e-38 129.0 1.1 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KII86063.1 - 1.3e-05 25.0 0.6 1.3e-05 25.0 0.6 3.2 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KII86063.1 - 4.5 7.4 7.3 0.8 9.8 0.1 3.3 3 0 0 3 3 3 0 G-patch domain Aldose_epim PF01263.20 KII86064.1 - 2e-26 93.0 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase AA_permease PF00324.21 KII86065.1 - 1.8e-127 425.9 37.6 2e-127 425.7 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII86065.1 - 4.9e-35 121.2 41.0 6e-35 120.9 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease LpxI_N PF17930.1 KII86065.1 - 0.15 11.9 0.1 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 LpxI N-terminal domain Glyco_transf_21 PF13506.6 KII86065.1 - 0.16 11.5 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Methyltransf_23 PF13489.6 KII86066.1 - 1.5e-14 54.2 0.0 3.3e-14 53.1 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII86066.1 - 8.7e-12 45.6 0.0 3.7e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86066.1 - 1.9e-11 44.6 0.0 2.5e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII86066.1 - 2.2e-10 41.1 0.0 1.9e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KII86066.1 - 0.00065 19.5 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII86066.1 - 0.0051 16.4 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KII86066.1 - 0.0075 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NNMT_PNMT_TEMT PF01234.17 KII86066.1 - 0.02 14.1 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family CheR PF01739.18 KII86066.1 - 0.025 14.1 0.0 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_24 PF13578.6 KII86066.1 - 0.026 15.5 0.0 0.066 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 KII86068.1 - 8.4e-64 215.2 3.4 7.1e-33 114.4 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KII86068.1 - 1.8e-60 204.9 0.0 2.7e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KII86068.1 - 1.8e-15 57.2 0.0 3.6e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KII86068.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 KII86068.1 - 0.14 12.0 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 PH domain CNH PF00780.22 KII86069.1 - 2.6e-41 142.1 0.0 3.1e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 CNH domain 4HBT_2 PF13279.6 KII86070.1 - 3.2e-11 43.8 0.0 5.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KII86070.1 - 3.1e-06 27.5 0.0 5.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KII86070.1 - 0.0056 16.0 0.0 0.081 12.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-ACP thioesterase Cellulase PF00150.18 KII86072.1 - 2e-12 47.1 0.0 4.2e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DAGAT PF03982.13 KII86073.1 - 7.4e-103 343.5 0.0 9.3e-103 343.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3429 PF11911.8 KII86073.1 - 0.026 14.8 2.9 0.052 13.8 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) CAP_GLY PF01302.25 KII86074.1 - 5.7e-26 90.3 1.5 8.8e-26 89.7 1.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KII86074.1 - 6.7e-24 84.2 0.0 1.2e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KII86074.1 - 0.045 13.5 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family AAA PF00004.29 KII86075.1 - 4.2e-96 318.4 0.0 1.5e-46 158.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII86075.1 - 5.4e-24 83.7 7.4 2.4e-11 43.2 0.3 3.3 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KII86075.1 - 2.1e-18 66.3 0.3 1.2e-17 63.9 0.3 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KII86075.1 - 3.2e-14 53.0 0.0 1.6e-05 24.7 0.0 3.2 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KII86075.1 - 1.9e-13 50.9 0.0 1.6e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KII86075.1 - 4.9e-12 46.2 0.0 5.3e-06 26.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 KII86075.1 - 1.6e-11 43.8 0.0 3.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KII86075.1 - 2.5e-11 43.7 0.5 3.3e-05 23.9 0.1 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII86075.1 - 1.7e-10 41.6 0.1 0.0029 18.0 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 KII86075.1 - 1e-09 38.1 0.1 0.0015 17.8 0.0 2.5 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KII86075.1 - 2.8e-09 37.4 0.1 0.027 14.7 0.0 4.2 3 2 0 3 3 2 2 AAA domain Vps4_C PF09336.10 KII86075.1 - 3.1e-08 33.5 0.3 1.7e-06 27.9 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KII86075.1 - 9.2e-08 31.7 0.4 0.0058 16.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KII86075.1 - 2e-07 31.6 0.0 0.009 16.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KII86075.1 - 3.5e-07 30.1 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KII86075.1 - 1.5e-06 28.6 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 KII86075.1 - 1.5e-06 28.3 0.0 0.024 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KII86075.1 - 1.6e-06 27.8 0.4 0.21 11.2 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_7 PF12775.7 KII86075.1 - 2.1e-06 27.4 0.2 0.011 15.3 0.0 2.9 3 1 0 3 3 2 2 P-loop containing dynein motor region ATPase PF06745.13 KII86075.1 - 5.9e-06 25.8 0.2 0.98 8.7 0.0 3.5 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 KII86075.1 - 6.3e-06 25.5 0.2 0.006 15.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KII86075.1 - 9.2e-06 26.0 0.0 0.073 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KII86075.1 - 1.7e-05 24.6 0.0 0.28 10.9 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KII86075.1 - 2e-05 24.4 0.1 0.18 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 KII86075.1 - 2.1e-05 25.0 0.0 0.13 12.8 0.0 3.6 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 KII86075.1 - 7.1e-05 22.7 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_17 PF13207.6 KII86075.1 - 7.3e-05 23.2 0.2 0.91 9.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KII86075.1 - 8.2e-05 21.9 0.0 0.021 14.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KII86075.1 - 0.00016 21.5 0.7 0.67 9.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 KII86075.1 - 0.00017 21.1 0.3 0.68 9.3 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein TsaE PF02367.17 KII86075.1 - 0.00018 21.5 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KII86075.1 - 0.0002 21.2 0.0 0.56 10.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KII86075.1 - 0.00022 21.3 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KII86075.1 - 0.00045 20.0 0.0 0.15 11.8 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KII86075.1 - 0.0009 19.2 0.1 0.21 11.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 KII86075.1 - 0.00097 19.1 0.2 2.8 7.8 0.0 3.7 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KII86075.1 - 0.0015 18.2 0.5 1.3 8.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 KII86075.1 - 0.0022 17.3 0.0 2 7.6 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin DUF2075 PF09848.9 KII86075.1 - 0.0027 17.0 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KII86075.1 - 0.0037 17.6 1.8 2.5 8.4 0.0 3.6 3 1 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.6 KII86075.1 - 0.0037 17.4 0.0 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain UFD1 PF03152.14 KII86075.1 - 0.0042 16.6 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 T2SSE PF00437.20 KII86075.1 - 0.01 14.9 0.0 0.36 9.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin2 PF13189.6 KII86075.1 - 0.013 15.6 0.7 3.7 7.7 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase-like family NB-ARC PF00931.22 KII86075.1 - 0.015 14.5 0.0 0.85 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 KII86075.1 - 0.021 14.2 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KII86075.1 - 0.022 14.5 0.3 4.3 7.0 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase NTPase_1 PF03266.15 KII86075.1 - 0.023 14.6 0.4 4 7.3 0.0 3.4 3 0 0 3 3 3 0 NTPase KAP_NTPase PF07693.14 KII86075.1 - 0.034 13.4 0.0 0.58 9.3 0.0 2.5 2 1 1 3 3 3 0 KAP family P-loop domain AFG1_ATPase PF03969.16 KII86075.1 - 0.069 12.0 0.0 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_6 PF12774.7 KII86075.1 - 0.22 10.5 0.1 11 4.9 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Hydin_ADK PF17213.3 KII86075.1 - 1.2 9.4 5.4 21 5.3 0.0 4.1 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain SE PF08491.10 KII86078.1 - 2.2e-96 322.2 0.0 2.8e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KII86078.1 - 4.9e-13 49.0 0.9 1.3e-11 44.3 0.9 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII86078.1 - 5.9e-10 39.3 0.1 0.00069 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII86078.1 - 0.00012 21.4 3.6 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KII86078.1 - 0.00029 20.2 0.0 0.00063 19.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII86078.1 - 0.00078 18.6 1.3 0.044 12.8 1.3 2.8 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KII86078.1 - 0.00095 18.1 0.2 0.48 9.2 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KII86078.1 - 0.0015 18.5 0.4 0.098 12.6 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KII86078.1 - 0.0095 15.2 0.2 0.11 11.7 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KII86078.1 - 0.01 16.1 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KII86078.1 - 0.52 9.3 2.9 5.2 6.0 2.9 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A DnaJ PF00226.31 KII86079.1 - 5.6e-09 36.0 0.0 9.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain GMC_oxred_N PF00732.19 KII86080.1 - 1.6e-58 198.4 0.1 2.7e-58 197.7 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII86080.1 - 5.5e-32 111.3 0.0 1e-31 110.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KII86080.1 - 0.00019 21.6 0.1 0.00056 20.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII86080.1 - 0.0023 17.1 0.2 0.0091 15.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KII86080.1 - 0.0083 15.2 0.4 0.013 14.6 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KII86080.1 - 0.049 13.2 0.6 0.14 11.7 0.6 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1727 PF08353.10 KII86081.1 - 0.053 13.5 0.3 0.29 11.1 0.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Pox_A_type_inc PF04508.12 KII86081.1 - 0.1 12.5 0.1 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Takusan PF04822.13 KII86081.1 - 0.18 11.7 8.7 0.18 11.7 0.1 3.8 2 1 1 3 3 3 0 Takusan DUF4094 PF13334.6 KII86081.1 - 1.2 9.6 18.3 8.4 6.9 0.4 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) Cu-oxidase PF00394.22 KII86082.1 - 4.3e-45 153.7 0.1 1.4e-41 142.2 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII86082.1 - 4.1e-41 139.9 1.8 2.3e-38 131.0 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII86082.1 - 1.6e-36 124.9 0.9 3e-34 117.6 0.1 3.3 3 0 0 3 3 3 1 Multicopper oxidase FAD_binding_3 PF01494.19 KII86083.1 - 4.5e-20 72.2 0.2 6.1e-19 68.5 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KII86083.1 - 0.00035 20.7 0.1 0.0011 19.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII86083.1 - 0.00041 19.7 0.0 0.00086 18.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII86083.1 - 0.025 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KII86083.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KII86083.1 - 0.14 10.9 0.6 0.25 10.0 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KII86084.1 - 3.7e-20 72.5 0.0 8e-19 68.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KII86084.1 - 0.013 14.4 0.7 0.2 10.4 0.1 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KII86084.1 - 0.03 13.5 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII86084.1 - 0.1 12.8 0.3 0.29 11.4 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KII86084.1 - 0.21 11.6 1.5 9.9 6.1 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KII86085.1 - 1.2e-12 47.7 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KII86085.1 - 0.054 12.5 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 KII86086.1 - 8.9e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII86086.1 - 0.00013 21.7 0.1 0.00013 21.7 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII86086.1 - 0.00023 20.5 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII86086.1 - 0.00029 20.0 0.3 0.00037 19.7 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KII86086.1 - 0.0029 16.9 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KII86086.1 - 0.007 15.1 0.1 0.01 14.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KII86086.1 - 0.048 12.9 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KII86087.1 - 3.6e-18 65.9 0.0 2.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KII86087.1 - 0.05 12.8 0.0 6.7 5.9 0.0 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MazG_C PF18722.1 KII86088.1 - 0.054 13.0 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 MazG C-terminal domain Questin_oxidase PF14027.6 KII86089.1 - 1.9e-70 238.1 0.1 3.2e-69 234.1 0.1 2.0 1 1 0 1 1 1 1 Questin oxidase-like NADH5_C PF06455.11 KII86089.1 - 0.17 11.4 0.1 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus SRF-TF PF00319.18 KII86090.1 - 6.5e-22 76.8 0.1 1.1e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Methyltransf_15 PF09445.10 KII86092.1 - 4.6e-35 120.6 0.0 9.5e-27 93.6 0.0 2.3 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KII86092.1 - 4e-07 30.6 0.0 8.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII86092.1 - 6.3e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KII86092.1 - 9.2e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KII86092.1 - 0.00062 19.6 0.0 0.0019 18.0 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KII86092.1 - 0.001 19.7 0.0 0.0026 18.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 KII86092.1 - 0.022 14.4 0.0 0.28 10.8 0.0 2.5 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 KII86092.1 - 0.027 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KII86092.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KII86092.1 - 0.12 11.3 0.2 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase SAM_MT PF04445.13 KII86092.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase DUF5641 PF18701.1 KII86094.1 - 0.1 12.8 1.7 0.33 11.1 1.7 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5641) MULE PF10551.9 KII86095.1 - 3.7e-07 30.5 0.0 7.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain HEAT_2 PF13646.6 KII86096.1 - 0.0001 22.6 9.6 3 8.3 0.0 6.3 5 2 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 KII86096.1 - 0.00041 20.8 9.3 0.044 14.3 0.1 6.4 6 1 0 6 6 6 1 HEAT-like repeat Arm PF00514.23 KII86096.1 - 0.0037 17.2 0.0 0.026 14.6 0.0 2.6 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KII86096.1 - 0.017 15.3 0.3 23 5.2 0.0 4.3 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KII86096.1 - 0.49 10.8 16.7 7.2 7.2 0.0 7.7 10 0 0 10 10 10 0 HEAT repeat zf-MYND PF01753.18 KII86097.1 - 3.2e-12 46.3 14.6 5.6e-12 45.6 14.6 1.4 1 0 0 1 1 1 1 MYND finger CENP-M PF11111.8 KII86097.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) zf-C6H2 PF15801.5 KII86097.1 - 0.71 10.2 11.8 0.23 11.8 8.7 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KII86097.1 - 1.2 9.3 4.8 3 8.0 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 AAA_2 PF07724.14 KII86098.1 - 1.6e-45 155.3 0.0 2.2e-42 145.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KII86098.1 - 3e-34 117.1 0.4 3e-34 117.1 0.4 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KII86098.1 - 1e-21 76.8 1.5 1.8e-21 76.0 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KII86098.1 - 9.8e-19 68.1 0.1 5.1e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KII86098.1 - 1.8e-17 63.7 0.0 2e-10 40.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII86098.1 - 3.9e-10 40.1 0.1 0.00084 19.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KII86098.1 - 4.2e-10 40.3 2.1 6.3e-05 23.4 0.1 4.2 3 2 2 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KII86098.1 - 5.2e-08 32.8 0.0 2.4e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KII86098.1 - 2e-06 27.3 0.2 0.13 11.6 0.0 3.1 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KII86098.1 - 2.9e-06 26.9 0.0 0.033 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 KII86098.1 - 7.6e-06 26.0 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KII86098.1 - 8.1e-06 25.7 0.1 0.21 11.3 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KII86098.1 - 1.1e-05 26.0 0.0 0.18 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KII86098.1 - 9e-05 22.4 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 KII86098.1 - 9.1e-05 23.0 2.8 0.012 16.1 0.0 3.1 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 KII86098.1 - 0.00013 22.3 1.0 0.36 11.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain RuvB_N PF05496.12 KII86098.1 - 0.00022 21.0 2.6 0.99 9.1 0.0 3.6 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KII86098.1 - 0.00054 20.2 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KII86098.1 - 0.0007 20.0 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 KII86098.1 - 0.00081 19.4 7.3 0.077 12.9 0.1 4.0 3 2 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KII86098.1 - 0.0015 18.9 0.1 0.37 11.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 KII86098.1 - 0.0063 16.5 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KII86098.1 - 0.0073 16.0 0.1 5.3 6.9 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KII86098.1 - 0.0084 15.8 0.0 4.5 6.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KII86098.1 - 0.0084 16.0 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DNA_pol3_delta2 PF13177.6 KII86098.1 - 0.0093 15.8 0.0 0.053 13.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_21 PF13304.6 KII86098.1 - 0.015 15.1 0.1 3.8 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KII86098.1 - 0.016 14.8 0.0 0.6 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KII86098.1 - 0.018 15.2 0.0 4.5 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KII86098.1 - 0.029 13.4 0.6 0.38 9.8 0.2 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KII86098.1 - 0.047 13.6 1.7 3.3 7.6 0.0 3.5 4 1 0 4 4 2 0 NTPase SRP54 PF00448.22 KII86098.1 - 0.053 13.2 0.0 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5517 PF17639.2 KII86098.1 - 0.078 13.3 0.0 11 6.4 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5517) PduV-EutP PF10662.9 KII86098.1 - 0.083 12.6 0.0 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.11 KII86098.1 - 0.088 12.7 0.0 25 4.8 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KII86098.1 - 0.11 12.5 0.0 34 4.6 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase ResIII PF04851.15 KII86098.1 - 0.14 12.2 0.1 43 4.0 0.0 3.2 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KII86098.1 - 0.2 11.4 5.2 1.4 8.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KII86098.1 - 0.24 11.1 8.9 1.1 9.0 0.0 4.1 3 1 1 4 4 3 0 AAA domain AAA_23 PF13476.6 KII86098.1 - 0.49 10.9 20.0 0.77 10.2 0.0 3.8 3 1 1 4 4 3 0 AAA domain Seryl_tRNA_N PF02403.22 KII86098.1 - 5.1 7.4 10.3 14 6.0 10.3 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3808 PF10300.9 KII86100.1 - 4.4e-68 230.1 0.0 6.6e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 KII86100.1 - 0.0002 21.2 7.6 0.057 13.6 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII86100.1 - 0.0011 19.2 2.2 0.71 10.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII86100.1 - 0.0073 16.1 3.7 2 8.4 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII86100.1 - 0.064 13.3 0.1 28 5.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat K_trans PF02705.16 KII86101.1 - 1.3e-172 575.0 17.3 1.7e-172 574.7 17.3 1.1 1 0 0 1 1 1 1 K+ potassium transporter Glyco_hydro_15 PF00723.21 KII86105.1 - 2.7e-95 319.8 0.2 3.2e-95 319.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GCV_T PF01571.21 KII86106.1 - 4.9e-83 278.4 0.0 5.9e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KII86106.1 - 1.2e-20 73.2 0.1 2.2e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RCS1 PF07326.11 KII86107.1 - 0.0058 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 Regulator of chromosome segregation 1 Di19_C PF14571.6 KII86108.1 - 0.084 13.4 1.7 0.25 11.9 1.7 1.7 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal SHS2_Rpb7-N PF03876.17 KII86109.1 - 1.6e-13 50.8 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KII86109.1 - 2e-11 44.1 0.5 5e-11 42.8 0.5 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KII86109.1 - 0.014 15.7 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Sortilin-Vps10 PF15902.5 KII86110.1 - 9.3e-297 983.8 7.8 8.9e-156 519.1 0.1 2.5 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KII86110.1 - 1e-92 309.1 14.0 5.4e-52 176.6 4.0 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KII86110.1 - 1.2e-09 36.7 42.6 0.6 10.3 0.1 12.4 12 0 0 12 12 12 5 BNR/Asp-box repeat BNR_2 PF13088.6 KII86110.1 - 1.7e-07 30.8 1.9 0.31 10.3 0.1 5.6 5 2 0 5 5 5 2 BNR repeat-like domain CHB_HEX_C PF03174.13 KII86110.1 - 0.015 15.3 3.3 9.7 6.3 0.0 5.7 7 1 1 8 8 8 0 Chitobiase/beta-hexosaminidase C-terminal domain Fe_dep_repr_C PF02742.15 KII86110.1 - 0.044 13.9 0.0 0.29 11.2 0.0 2.4 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain BNR_6 PF15899.5 KII86110.1 - 0.2 11.8 2.3 3 8.2 0.1 4.2 3 0 0 3 3 3 0 BNR-Asp box repeat Mo-co_dimer PF03404.16 KII86110.1 - 1.2 9.2 3.9 18 5.3 0.1 4.8 6 2 0 6 6 6 0 Mo-co oxidoreductase dimerisation domain AAA_16 PF13191.6 KII86116.1 - 3.4e-07 30.8 0.0 0.0009 19.7 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KII86116.1 - 0.00022 21.2 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KII86116.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KII86116.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_P4 PF11602.8 KII86116.1 - 0.15 11.2 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Sigma54_activat PF00158.26 KII86116.1 - 0.22 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 KII86117.1 - 2.3e-08 34.6 0.1 4e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain NACHT PF05729.12 KII86117.1 - 0.00035 20.5 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KII86117.1 - 0.0098 15.1 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KII86117.1 - 0.025 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SAM_adeno_trans PF01887.16 KII86117.1 - 0.06 12.8 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Sigma54_activat PF00158.26 KII86117.1 - 0.15 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain BDHCT_assoc PF16204.5 KII86122.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein SDA1 PF05285.12 KII86125.1 - 1.6 8.1 17.8 2.4 7.5 17.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KII86125.1 - 8.6 4.4 18.8 11 4.1 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.6 KII86128.1 - 8e-10 39.4 0.0 2e-07 31.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KII86128.1 - 6.9e-05 22.8 0.0 9.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KII86128.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KII86128.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII86128.1 - 0.063 12.5 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 KII86128.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KII86128.1 - 0.23 11.2 0.1 0.52 10.0 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein WD40_4 PF16300.5 KII86129.1 - 3.2e-17 62.1 0.2 7.4e-17 61.0 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat DUF1899 PF08953.11 KII86129.1 - 2.3e-15 56.2 0.1 6.4e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KII86129.1 - 1.2e-14 54.4 2.2 0.00073 20.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII86129.1 - 3.7e-05 24.0 0.0 0.27 11.6 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4931 PF16285.5 KII86130.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) RBM39linker PF15519.6 KII86132.1 - 0.078 14.1 1.0 0.11 13.6 1.0 1.2 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF4218 PF13960.6 KII86134.1 - 0.0065 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plavaka PF18759.1 KII86134.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Plavaka transposase DM PF00751.18 KII86134.1 - 0.089 12.7 0.6 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 DM DNA binding domain zf-Dof PF02701.15 KII86135.1 - 0.086 13.0 0.4 0.24 11.6 0.4 1.7 1 0 0 1 1 1 0 Dof domain, zinc finger VGCC_beta4Aa_N PF12052.8 KII86135.1 - 0.11 12.6 1.4 6.5 6.9 0.1 2.8 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal zf-MYND PF01753.18 KII86136.1 - 3e-10 40.0 9.2 5.1e-10 39.3 9.2 1.4 1 0 0 1 1 1 1 MYND finger DUF2267 PF10025.9 KII86136.1 - 0.016 15.4 0.2 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) zf-C6H2 PF15801.5 KII86136.1 - 0.32 11.3 8.5 0.73 10.2 8.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KII86136.1 - 0.53 10.4 5.7 0.22 11.6 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KII86139.1 - 2e-10 40.6 4.9 4.9e-10 39.3 4.9 1.7 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KII86139.1 - 0.21 11.7 1.9 0.45 10.7 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KII86139.1 - 0.74 10.2 6.1 1.5 9.2 6.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII86140.1 - 7.6e-09 35.5 10.9 1.5e-08 34.5 10.9 1.5 1 0 0 1 1 1 1 MYND finger PapA_C PF16911.5 KII86140.1 - 0.0061 16.6 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus zf-Mss51 PF13824.6 KII86140.1 - 0.095 12.8 5.6 0.26 11.4 5.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KII86140.1 - 0.65 10.3 7.3 1.4 9.3 7.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding adh_short_C2 PF13561.6 KII86142.1 - 2.7e-30 105.7 1.2 3.6e-30 105.3 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII86142.1 - 3.7e-17 62.4 0.1 5.1e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Oxidored_nitro PF00148.19 KII86142.1 - 0.0033 16.2 0.0 0.0033 16.2 0.0 1.3 1 1 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.21 KII86142.1 - 0.017 15.2 0.2 0.036 14.2 0.2 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII86142.1 - 0.047 13.0 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.7 KII86143.1 - 1e-11 44.5 0.1 3.1e-11 43.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII86144.1 - 5.3e-10 39.0 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86144.1 - 0.0082 16.0 0.2 0.03 14.2 0.2 2.0 1 1 0 1 1 1 1 F-box domain F-box PF00646.33 KII86145.1 - 0.00029 20.7 0.0 0.0012 18.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain TAN PF11640.8 KII86145.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair F-box-like PF12937.7 KII86145.1 - 0.021 14.7 1.5 0.088 12.7 0.0 2.8 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.7 KII86147.1 - 2.7e-10 40.0 3.8 5.7e-10 38.9 3.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86147.1 - 0.0016 18.2 2.1 0.0016 18.2 2.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII86148.1 - 2.8e-11 43.1 1.2 5e-11 42.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF1635 PF07795.11 KII86148.1 - 0.14 12.0 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) F-box_5 PF18511.1 KII86148.1 - 0.62 9.7 2.2 0.81 9.3 0.1 2.0 2 0 0 2 2 2 0 F-box F-box PF00646.33 KII86148.1 - 2.7 8.0 5.2 3.8 7.5 0.1 3.2 3 1 0 3 3 3 0 F-box domain BTB PF00651.31 KII86149.1 - 3.1e-05 24.2 0.0 5.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RICTOR_V PF14668.6 KII86149.1 - 0.056 13.7 0.0 57 4.1 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 BTB PF00651.31 KII86150.1 - 8.3e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 KII86151.1 - 8.2e-08 32.0 2.2 8.2e-08 32.0 2.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII86151.1 - 0.0066 16.3 0.7 0.035 14.0 0.7 2.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII86152.1 - 6.3e-09 35.6 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KII86152.1 - 0.098 13.3 0.2 5.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat F-box PF00646.33 KII86152.1 - 0.1 12.5 0.5 0.54 10.2 0.5 2.3 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 KII86153.1 - 3.1e-09 36.6 0.0 1.1e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86153.1 - 0.0018 18.1 0.0 0.0065 16.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KII86153.1 - 0.0023 18.3 3.1 5.3 7.6 0.1 4.9 4 3 1 5 5 5 2 Leucine Rich repeats (2 copies) Lipase_GDSL_2 PF13472.6 KII86154.1 - 3.8e-07 30.7 0.3 5.7e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII86154.1 - 1.4e-06 28.4 0.0 3.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GLTP PF08718.11 KII86155.1 - 2.1e-36 125.4 0.0 2.5e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) F-box-like PF12937.7 KII86156.1 - 7.7e-09 35.3 0.1 2.8e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like Ribosomal_L7Ae PF01248.26 KII86157.1 - 9e-23 79.8 1.0 1.5e-22 79.1 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KII86157.1 - 0.011 14.8 0.7 0.014 14.5 0.7 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) FAD_binding_3 PF01494.19 KII86158.1 - 3.2e-64 217.4 0.0 4.5e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII86158.1 - 3.7e-09 36.2 0.8 1e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII86158.1 - 4.7e-06 25.9 0.7 8e-06 25.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII86158.1 - 5.6e-06 25.3 0.2 1.8e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KII86158.1 - 5.5e-05 23.3 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KII86158.1 - 9.9e-05 21.6 0.1 0.00014 21.1 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KII86158.1 - 0.00011 21.9 1.2 0.00072 19.2 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII86158.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII86158.1 - 0.0016 17.9 0.2 0.0027 17.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII86158.1 - 0.0016 18.9 0.3 0.42 11.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII86158.1 - 0.0034 16.7 0.3 0.0076 15.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family LEA_6 PF10714.9 KII86158.1 - 0.0058 16.7 0.2 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein 18 Glu_dehyd_C PF16912.5 KII86158.1 - 0.044 13.3 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KII86158.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KII86158.1 - 0.08 12.0 0.2 0.12 11.3 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 KII86158.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Plavaka PF18759.1 KII86160.1 - 7.4e-122 406.6 0.0 1.1e-121 406.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_6 PF13912.6 KII86160.1 - 0.0012 18.8 2.3 0.0027 17.6 2.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KII86160.1 - 2.8 8.6 9.7 0.088 13.3 2.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII86160.1 - 3 8.9 8.2 0.31 12.0 2.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SPT6_acidic PF14632.6 KII86161.1 - 3.3 8.4 7.1 3.6 8.2 1.6 2.8 2 1 1 3 3 3 0 Acidic N-terminal SPT6 ERCC4 PF02732.15 KII86162.1 - 2.9e-20 73.0 0.0 5.3e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Cir_N PF10197.9 KII86163.1 - 3.5e-07 30.3 0.7 3.5e-07 30.3 0.7 2.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Lipoprotein_20 PF13942.6 KII86163.1 - 0.21 11.5 2.9 9.8 6.1 0.1 2.4 2 0 0 2 2 2 0 YfhG lipoprotein DUF5112 PF17139.4 KII86163.1 - 0.45 10.0 1.2 0.69 9.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Lipase_3 PF01764.25 KII86164.1 - 1.2e-19 70.5 0.1 1.7e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) F-box-like PF12937.7 KII86165.1 - 1.9e-05 24.5 0.0 6.9e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF4051 PF13260.6 KII86165.1 - 0.18 11.6 1.2 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Snapin_Pallidin PF14712.6 KII86166.1 - 0.0087 16.5 0.9 0.0087 16.5 0.9 2.2 2 1 0 2 2 2 1 Snapin/Pallidin WXG100 PF06013.12 KII86166.1 - 0.03 14.5 3.4 0.03 14.5 3.4 2.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Fez1 PF06818.15 KII86166.1 - 0.068 13.6 8.2 0.11 12.9 8.2 1.4 1 0 0 1 1 1 0 Fez1 Syntaxin PF00804.25 KII86166.1 - 0.088 12.5 6.2 0.2 11.3 4.4 2.2 2 1 1 3 3 3 0 Syntaxin SPATA1_C PF15743.5 KII86166.1 - 0.22 11.6 6.0 0.93 9.6 6.0 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus ATG16 PF08614.11 KII86166.1 - 0.23 11.7 18.9 0.39 10.9 18.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KII86166.1 - 0.41 10.7 3.4 0.8 9.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KII86166.1 - 0.63 10.1 5.4 1.6 8.7 5.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EURL PF06937.11 KII86166.1 - 0.82 9.0 3.0 1.1 8.6 3.0 1.1 1 0 0 1 1 1 0 EURL protein CENP-O PF09496.10 KII86166.1 - 1.1 9.1 4.2 1.6 8.7 4.2 1.2 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Fzo_mitofusin PF04799.13 KII86166.1 - 1.5 8.4 7.7 2.6 7.5 2.4 2.3 1 1 1 2 2 2 0 fzo-like conserved region UPF0242 PF06785.11 KII86166.1 - 1.8 8.7 6.2 0.39 10.8 1.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KII86166.1 - 3.6 7.9 5.4 1.2 9.4 0.2 2.9 5 0 0 5 5 3 0 Homeobox associated leucine zipper Atg14 PF10186.9 KII86166.1 - 8.9 5.3 9.8 12 4.8 9.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Retrotran_gag_2 PF14223.6 KII86168.1 - 6.6e-15 55.0 0.0 7.1e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type F-box-like PF12937.7 KII86169.1 - 0.00016 21.5 0.2 0.00066 19.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like ketoacyl-synt PF00109.26 KII86169.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain F-box-like PF12937.7 KII86170.1 - 2.8e-05 23.9 0.2 0.00014 21.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like GST_N_2 PF13409.6 KII86171.1 - 2.5e-22 79.0 0.0 6.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII86171.1 - 2e-14 53.4 0.0 4.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII86171.1 - 3.8e-07 30.2 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII86171.1 - 6.1e-05 23.4 0.0 0.00078 19.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KII86171.1 - 0.00015 21.9 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_3 PF01764.25 KII86173.1 - 9.3e-20 70.9 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Sun2_CC2 PF18580.1 KII86173.1 - 0.12 12.7 0.5 0.22 11.8 0.5 1.3 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 Hydrolase_4 PF12146.8 KII86173.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 KII86174.1 - 1e-67 228.9 0.0 1.2e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KII86175.1 - 1.4e-21 76.5 0.2 6.8e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII86175.1 - 1.3e-15 57.1 0.0 2.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII86175.1 - 6.5e-09 35.9 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII86175.1 - 3.5e-05 23.9 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII86175.1 - 0.00016 22.0 0.0 0.0032 17.8 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1556 PF07590.11 KII86177.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) ATP-synt_I PF03899.15 KII86178.1 - 0.17 12.2 16.6 0.3 11.5 4.8 2.8 1 1 2 3 3 3 0 ATP synthase I chain F-box-like PF12937.7 KII86179.1 - 0.0008 19.3 1.2 0.0079 16.1 1.3 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII86181.1 - 1e-06 28.5 0.6 2.9e-06 27.1 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII86181.1 - 0.0025 18.2 0.0 0.084 13.3 0.0 3.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KII86181.1 - 0.087 12.7 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 F-box domain APG6_N PF17675.1 KII86181.1 - 0.11 13.1 3.2 0.18 12.3 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region LRR_8 PF13855.6 KII86181.1 - 0.13 12.0 0.2 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat DUF3450 PF11932.8 KII86181.1 - 0.16 11.2 0.8 0.25 10.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CREPT PF16566.5 KII86181.1 - 0.21 11.8 1.4 0.23 11.6 0.3 1.6 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 KII86181.1 - 0.65 10.5 7.5 1.3 9.6 7.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB F-box-like PF12937.7 KII86182.1 - 3.1e-07 30.2 1.7 7.8e-07 28.9 0.1 2.4 2 0 0 2 2 2 1 F-box-like BESS PF02944.20 KII86182.1 - 0.24 11.3 0.6 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 BESS motif F-box PF00646.33 KII86182.1 - 0.32 10.9 2.7 3 7.8 0.2 3.1 3 0 0 3 3 3 0 F-box domain EutQ PF06249.12 KII86183.1 - 1.5e-11 44.3 0.3 1.5e-11 44.2 0.3 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KII86183.1 - 0.00085 19.0 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Pox_RNA_pol PF03293.14 KII86183.1 - 0.014 15.1 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Cupin_2 PF07883.11 KII86183.1 - 0.022 14.5 0.1 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Cupin domain F-box-like PF12937.7 KII86185.1 - 9.6e-05 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII86186.1 - 4.1e-05 23.4 0.2 0.00048 20.0 0.2 2.5 2 0 0 2 2 2 1 F-box-like DUF43 PF01861.16 KII86186.1 - 0.13 11.5 0.0 6.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain DEAD PF00270.29 KII86188.1 - 1.3e-18 67.4 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII86188.1 - 2.1e-14 53.8 0.0 1.5e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII86188.1 - 3.5e-08 33.6 0.0 5.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2620 PF10941.8 KII86188.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 AAA_14 PF13173.6 KII86188.1 - 0.033 14.2 0.0 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SecA_DEAD PF07517.14 KII86188.1 - 0.17 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain zf-CCHC PF00098.23 KII86189.1 - 0.015 15.3 0.2 0.015 15.3 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle AAA_27 PF13514.6 KII86190.1 - 0.069 12.7 0.0 0.099 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain UBA_e1_thiolCys PF10585.9 KII86191.1 - 0.061 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site SURF2 PF05477.11 KII86191.1 - 0.16 11.6 1.9 0.32 10.6 1.9 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LMBR1 PF04791.16 KII86192.1 - 5 5.9 7.7 11 4.8 7.7 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein 4HBT PF03061.22 KII86193.1 - 2.5e-12 47.0 0.0 4.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KII86193.1 - 0.00067 20.0 0.2 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 Thioesterase-like superfamily F-box-like PF12937.7 KII86194.1 - 3.1e-06 27.0 0.2 9.7e-06 25.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII86195.1 - 1.6e-05 24.7 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Phosducin PF02114.16 KII86196.1 - 7.2e-16 57.9 0.1 6e-06 25.4 0.0 3.1 2 1 1 3 3 3 3 Phosducin Glyco_hydro_61 PF03443.14 KII86197.1 - 1.1e-57 195.3 0.3 1.2e-57 195.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LRR_4 PF12799.7 KII86198.1 - 2.6e-05 24.5 0.4 15 6.1 0.0 5.1 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII86198.1 - 0.071 13.0 5.1 0.18 11.7 0.9 3.1 3 0 0 3 3 3 0 F-box-like OTT_1508_deam PF14441.6 KII86200.1 - 4.8e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF659 PF04937.15 KII86202.1 - 1.6e-11 44.3 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) TPR_12 PF13424.6 KII86203.1 - 2.7e-36 123.7 33.0 4e-10 39.8 4.8 5.8 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KII86203.1 - 1e-29 100.2 32.0 0.0025 17.8 0.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat SNAP PF14938.6 KII86203.1 - 3.3e-17 62.8 30.6 1.6e-08 34.3 3.5 3.7 1 1 4 5 5 5 5 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 KII86203.1 - 2.1e-12 47.4 35.3 0.1 13.2 1.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KII86203.1 - 8.5e-11 41.2 27.2 0.56 10.1 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII86203.1 - 4.8e-10 39.9 18.2 0.18 12.5 0.1 7.5 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KII86203.1 - 3.4e-08 33.3 31.2 9.9e-05 21.9 11.5 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 KII86203.1 - 6.6e-07 29.6 20.4 4.7 8.3 0.3 8.7 5 1 3 8 8 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 KII86203.1 - 1.4e-06 28.1 24.9 0.061 13.0 1.4 5.1 1 1 1 4 4 4 4 Tetratricopeptide repeat-like domain AAA_16 PF13191.6 KII86203.1 - 2.1e-06 28.2 2.2 0.00088 19.7 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain ANAPC3 PF12895.7 KII86203.1 - 2.9e-06 27.4 19.9 0.29 11.4 1.2 6.3 2 2 5 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KII86203.1 - 1.2e-05 25.0 32.5 1.3 9.0 0.5 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat RPN7 PF10602.9 KII86203.1 - 2.4e-05 24.1 4.8 0.025 14.3 0.1 3.7 1 1 3 4 4 4 1 26S proteasome subunit RPN7 CSN5_C PF18323.1 KII86203.1 - 0.00015 22.7 13.5 26 5.8 0.1 7.5 7 1 0 8 8 8 0 Cop9 signalosome subunit 5 C-terminal domain TPR_17 PF13431.6 KII86203.1 - 0.00015 21.9 18.7 25 5.6 0.1 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII86203.1 - 0.00036 20.3 22.0 7.9 6.8 0.1 8.0 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 KII86203.1 - 0.00042 20.2 16.0 4.1 7.5 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII86203.1 - 0.00051 19.7 29.0 2.3 8.0 0.2 8.3 8 0 0 8 8 8 1 TPR repeat NACHT PF05729.12 KII86203.1 - 0.00052 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NRN1 PF15056.6 KII86203.1 - 0.00057 19.9 13.0 6.9 6.8 0.1 6.7 4 2 3 7 7 7 0 Neuritin protein family Foie-gras_1 PF11817.8 KII86203.1 - 0.00063 19.4 5.2 0.91 9.1 0.1 3.5 2 1 2 4 4 4 3 Foie gras liver health family 1 AAA_22 PF13401.6 KII86203.1 - 0.0057 16.9 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arg_decarb_HB PF17810.1 KII86203.1 - 0.0068 16.6 20.9 11 6.3 0.4 7.6 6 2 2 8 8 8 0 Arginine decarboxylase helical bundle domain SHNi-TPR PF10516.9 KII86203.1 - 0.0068 15.8 8.8 6.3 6.3 0.0 6.4 7 0 0 7 7 7 0 SHNi-TPR TPR_4 PF07721.14 KII86203.1 - 0.029 15.0 7.9 15 6.6 0.1 6.2 8 0 0 8 8 4 0 Tetratricopeptide repeat NB-ARC PF00931.22 KII86203.1 - 0.034 13.3 0.0 0.09 11.9 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 KII86203.1 - 0.044 13.5 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF724 PF05266.14 KII86203.1 - 0.11 12.3 3.6 31 4.3 0.1 4.5 2 2 1 3 3 3 0 Protein of unknown function (DUF724) Semialdhyde_dhC PF02774.18 KII86203.1 - 0.12 12.5 0.3 9.5 6.2 0.0 3.3 3 2 1 4 4 3 0 Semialdehyde dehydrogenase, dimerisation domain QWRF PF04484.12 KII86203.1 - 0.26 11.0 2.0 3.8 7.2 0.1 3.0 3 1 0 3 3 3 0 QWRF family Chorion_S16 PF05836.12 KII86203.1 - 0.72 10.1 3.6 44 4.3 0.4 4.5 4 1 0 4 4 4 0 Chorion protein S16 Peripla_BP_2 PF01497.18 KII86203.1 - 4.2 6.9 8.6 29 4.1 0.2 4.2 3 1 3 6 6 6 0 Periplasmic binding protein DASH_Spc19 PF08287.11 KII86205.1 - 0.023 14.6 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 Spc19 Prefoldin_3 PF13758.6 KII86205.1 - 0.089 12.9 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Prefoldin subunit TPR_12 PF13424.6 KII86211.1 - 1.4e-46 156.7 39.6 8.9e-10 38.7 2.3 6.2 4 1 2 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KII86211.1 - 6.1e-33 110.3 33.9 0.01 15.9 0.2 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat SNAP PF14938.6 KII86211.1 - 7.6e-22 78.1 20.0 1.2e-10 41.3 1.0 3.5 1 1 2 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KII86211.1 - 2.2e-14 52.5 30.4 0.42 10.5 0.1 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KII86211.1 - 5e-12 45.8 39.3 3.8e-06 26.5 10.7 3.3 2 1 1 3 3 3 3 MalT-like TPR region TPR_10 PF13374.6 KII86211.1 - 1.9e-09 37.1 45.1 0.31 11.0 0.3 10.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII86211.1 - 3.4e-09 37.2 23.6 0.0052 17.4 1.6 7.6 5 3 2 7 7 7 4 Tetratricopeptide repeat AAA_16 PF13191.6 KII86211.1 - 7.2e-09 36.2 4.7 0.00071 20.0 0.1 4.3 3 2 0 3 3 3 2 AAA ATPase domain TPR_7 PF13176.6 KII86211.1 - 3e-06 26.9 32.0 6.3 7.1 0.1 10.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII86211.1 - 3.6e-06 27.3 22.9 19 6.4 0.0 9.5 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 KII86211.1 - 8.6e-06 25.8 20.8 22 5.7 0.1 9.7 10 0 0 10 10 9 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KII86211.1 - 1e-05 25.6 26.3 0.11 12.8 1.1 7.3 1 1 6 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KII86211.1 - 2e-05 24.2 39.9 1 9.1 0.4 10.1 10 0 0 10 10 10 3 TPR repeat SMC_hinge PF06470.13 KII86211.1 - 0.00014 22.1 1.7 1.3 9.3 0.1 5.6 2 1 5 7 7 6 1 SMC proteins Flexible Hinge Domain RPN7 PF10602.9 KII86211.1 - 0.0012 18.6 10.4 0.19 11.4 0.5 4.3 1 1 2 3 3 3 2 26S proteasome subunit RPN7 Sigma54_activat PF00158.26 KII86211.1 - 0.0013 18.5 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF724 PF05266.14 KII86211.1 - 0.0013 18.6 4.8 7.3 6.4 0.1 4.8 2 1 0 4 4 4 0 Protein of unknown function (DUF724) TPR_19 PF14559.6 KII86211.1 - 0.0014 19.1 50.1 1.8 9.1 0.2 9.8 5 3 4 9 9 9 1 Tetratricopeptide repeat NACHT PF05729.12 KII86211.1 - 0.0016 18.4 0.9 0.0079 16.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TPR_21 PF09976.9 KII86211.1 - 0.002 17.8 29.3 0.71 9.5 1.1 6.4 1 1 6 7 7 7 3 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 KII86211.1 - 0.0024 17.3 19.7 4.8 6.7 0.1 8.3 9 0 0 9 9 9 0 SHNi-TPR NB-ARC PF00931.22 KII86211.1 - 0.0027 16.9 0.0 0.14 11.3 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain HsbA PF12296.8 KII86211.1 - 0.0041 17.6 9.6 0.39 11.1 0.3 4.7 1 1 3 4 4 4 1 Hydrophobic surface binding protein A TPR_3 PF07720.12 KII86211.1 - 0.0046 16.9 16.0 12 6.0 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Arg_decarb_HB PF17810.1 KII86211.1 - 0.0047 17.1 23.4 10 6.5 0.2 9.1 7 2 3 10 10 9 0 Arginine decarboxylase helical bundle domain AAA_22 PF13401.6 KII86211.1 - 0.0053 17.0 0.0 0.027 14.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KII86211.1 - 0.0099 15.6 0.2 1.6 8.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF2254 PF10011.9 KII86211.1 - 0.018 13.9 1.2 10 4.8 0.0 4.5 2 2 3 6 6 6 0 Predicted membrane protein (DUF2254) TPR_4 PF07721.14 KII86211.1 - 0.02 15.5 10.8 40 5.2 0.1 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat CSN5_C PF18323.1 KII86211.1 - 0.028 15.3 17.0 43 5.1 0.1 8.3 8 1 0 9 9 9 0 Cop9 signalosome subunit 5 C-terminal domain KAP_NTPase PF07693.14 KII86211.1 - 0.031 13.5 0.0 4.4 6.4 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Tho2 PF11262.8 KII86211.1 - 0.039 13.2 4.6 13 4.9 0.1 4.5 4 2 0 4 4 4 0 Transcription factor/nuclear export subunit protein 2 Ldh_1_N PF00056.23 KII86211.1 - 0.043 13.9 0.0 5.6 7.1 0.0 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain SOAR PF16533.5 KII86211.1 - 0.2 11.6 5.8 22 5.1 0.1 4.6 3 2 2 5 5 5 0 STIM1 Orai1-activating region CobW_C PF07683.14 KII86211.1 - 0.27 11.2 1.7 76 3.3 0.0 4.3 4 1 1 5 5 4 0 Cobalamin synthesis protein cobW C-terminal domain DUF4141 PF13605.6 KII86211.1 - 0.5 9.7 7.6 1.7e+02 1.5 0.0 6.9 8 0 0 8 8 8 0 Domain of unknown function (DUF4141) ABC_tran PF00005.27 KII86211.1 - 1.1 9.8 4.1 13 6.3 0.1 3.4 3 0 0 3 3 2 0 ABC transporter FUSC-like PF12805.7 KII86211.1 - 1.6 7.8 22.2 0.13 11.3 1.3 4.3 1 1 4 5 5 5 0 FUSC-like inner membrane protein yccS Vps5 PF09325.10 KII86211.1 - 1.9 8.0 10.4 0.8 9.2 0.6 3.4 1 1 1 3 3 3 0 Vps5 C terminal like PARP_reg PF02877.14 KII86211.1 - 5.3 7.1 6.2 99 3.0 0.5 5.2 2 1 3 5 5 4 0 Poly(ADP-ribose) polymerase, regulatory domain F-box-like PF12937.7 KII86213.1 - 0.022 14.6 2.1 0.027 14.3 0.1 2.2 3 0 0 3 3 3 0 F-box-like DUF4813 PF16072.5 KII86213.1 - 0.078 12.6 6.8 0.1 12.2 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) LRR_4 PF12799.7 KII86214.1 - 0.0038 17.6 6.6 24 5.5 0.1 5.9 6 2 1 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII86214.1 - 0.012 15.4 1.2 0.09 12.7 1.2 2.6 1 0 0 1 1 1 0 F-box-like Epimerase PF01370.21 KII86215.1 - 8.7e-21 74.5 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII86215.1 - 4.4e-15 55.4 0.0 7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII86215.1 - 2.4e-10 40.6 0.2 3.9e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII86215.1 - 6.8e-09 35.3 0.1 5.9e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KII86215.1 - 8.6e-09 35.2 0.1 2.9e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KII86215.1 - 1.4e-06 28.1 0.1 2e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KII86215.1 - 0.017 14.6 0.7 0.032 13.7 0.3 1.7 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.6 KII86215.1 - 0.036 13.6 0.3 0.082 12.4 0.2 1.6 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Gemini_AL1_M PF08283.11 KII86215.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Geminivirus rep protein central domain FtsX PF02687.21 KII86216.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 FtsX-like permease family Epimerase PF01370.21 KII86217.1 - 1.7e-19 70.2 0.0 3.1e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII86217.1 - 5.6e-12 45.4 0.1 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KII86217.1 - 1.2e-10 40.9 0.0 1.9e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII86217.1 - 5.5e-10 39.4 1.0 1.5e-09 38.0 0.7 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII86217.1 - 5.8e-10 39.1 0.1 4.7e-09 36.1 0.1 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KII86217.1 - 2.4e-06 27.3 0.4 3.4e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KII86217.1 - 6.1e-05 22.6 1.5 0.00021 20.8 0.8 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII86217.1 - 0.0088 16.0 0.3 0.24 11.3 0.3 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KII86217.1 - 0.063 12.4 0.1 0.85 8.7 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain APG17 PF04108.12 KII86219.1 - 0.017 14.3 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 F-box PF00646.33 KII86220.1 - 0.0001 22.0 1.9 0.00027 20.7 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII86220.1 - 0.16 11.9 2.2 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KII86222.1 - 0.00053 19.8 0.1 0.00053 19.8 0.1 3.2 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 KII86222.1 - 0.0017 18.2 0.1 0.0017 18.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII86223.1 - 5.6e-06 26.1 0.1 1.5e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like AMP-binding PF00501.28 KII86225.1 - 2.6e-87 293.2 0.0 3.2e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII86225.1 - 2.4e-13 50.8 1.2 5.6e-13 49.7 1.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 KII86226.1 - 3e-19 69.4 0.0 3e-18 66.2 0.0 2.1 1 1 1 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KII86226.1 - 6.1e-05 23.6 0.0 0.00024 21.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86226.1 - 0.003 18.3 0.0 0.01 16.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII86226.1 - 0.0091 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KII86226.1 - 0.017 14.9 0.0 0.068 13.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KII86226.1 - 0.13 12.9 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KII86226.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein F-box-like PF12937.7 KII86227.1 - 6e-05 22.9 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 KII86228.1 - 1.1e-36 126.5 28.0 1.1e-36 126.5 28.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII86228.1 - 6.4e-14 51.7 4.7 6.4e-14 51.7 4.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.11 KII86228.1 - 0.0079 16.3 0.7 0.037 14.2 0.7 2.2 1 0 0 1 1 1 1 Membrane bound YbgT-like protein OATP PF03137.20 KII86228.1 - 0.011 14.1 0.4 0.011 14.1 0.4 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family APH PF01636.23 KII86231.1 - 2.3e-14 53.9 0.1 3e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII86231.1 - 0.0014 18.1 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KII86231.1 - 0.0015 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KII86231.1 - 0.0043 16.3 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 KII86231.1 - 0.054 12.4 0.0 6.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 KII86233.1 - 1.5e-62 211.4 0.0 5.6e-32 111.1 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KII86233.1 - 2.8e-47 161.5 3.7 1e-46 159.6 0.0 2.9 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KII86233.1 - 3.6e-29 101.9 0.0 1.2e-13 51.0 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 KII86233.1 - 4.9e-16 59.1 1.1 9.3e-16 58.2 0.2 2.0 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 KII86233.1 - 1.3e-09 37.8 0.0 1.3e-09 37.8 0.0 2.5 2 1 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 KII86233.1 - 0.0001 22.3 1.9 0.00028 20.9 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KII86233.1 - 0.00025 20.5 0.0 0.89 8.9 0.0 3.2 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII86233.1 - 0.041 12.7 0.0 0.041 12.7 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 KII86233.1 - 0.078 12.3 0.0 0.23 10.7 0.0 1.8 1 0 0 1 1 1 0 Kinase-like F-box-like PF12937.7 KII86234.1 - 0.00063 19.6 0.1 0.002 18.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII86235.1 - 1.5e-06 28.0 1.6 8.3e-06 25.6 0.2 2.8 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KII86236.1 - 4.8e-61 206.4 0.0 6e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86236.1 - 2.8e-28 98.9 0.0 3.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII86236.1 - 3.1e-06 26.7 0.0 5.7e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KII86236.1 - 0.0086 16.0 0.1 0.035 14.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII86236.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KII86236.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KII86236.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KII86236.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4407 PF14362.6 KII86238.1 - 0.33 10.3 10.8 0.44 9.8 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.13 KII86238.1 - 0.71 8.9 12.2 1 8.4 12.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NOA36 PF06524.12 KII86238.1 - 4.4 6.5 17.2 6.3 6.0 17.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4551 PF15087.6 KII86238.1 - 5 5.8 9.7 5.8 5.6 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase_Tyr PF07714.17 KII86240.1 - 1.2e-22 80.4 0.0 1.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII86240.1 - 5.7e-13 48.8 0.0 1e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Tim54 PF11711.8 KII86242.1 - 1.2 7.8 10.3 0.11 11.3 0.2 2.7 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 PBP PF01161.20 KII86243.1 - 1.6e-17 64.1 0.0 2e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Alpha-amylase PF00128.24 KII86244.1 - 1.1e-15 58.1 0.0 1.9e-13 50.7 0.0 2.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KII86244.1 - 1.9e-12 47.5 0.1 6.1e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Cerato-platanin PF07249.12 KII86244.1 - 0.78 9.9 4.6 0.42 10.8 1.8 1.9 2 0 0 2 2 2 0 Cerato-platanin adh_short_C2 PF13561.6 KII86246.1 - 1.2e-52 178.8 6.1 2.3e-50 171.4 6.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII86246.1 - 8.6e-48 162.4 2.0 1e-47 162.1 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII86246.1 - 2.2e-16 60.3 0.5 3.4e-16 59.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KII86246.1 - 0.011 16.4 0.1 0.021 15.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KII86246.1 - 0.018 15.0 1.1 0.028 14.3 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Metallophos_2 PF12850.7 KII86246.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain AdoHcyase_NAD PF00670.21 KII86246.1 - 0.15 12.2 1.1 0.25 11.4 1.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain A_deaminase PF00962.22 KII86247.1 - 2e-17 63.5 0.0 3.3e-17 62.8 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF3752 PF12572.8 KII86248.1 - 1.3e-42 145.9 6.3 1.3e-42 145.9 6.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Cullin PF00888.22 KII86249.1 - 2e-140 469.3 0.5 2.8e-140 468.8 0.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KII86249.1 - 2e-23 82.2 3.4 3.4e-23 81.5 1.7 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain DUF515 PF04415.12 KII86249.1 - 0.018 13.5 0.3 0.031 12.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) G-alpha PF00503.20 KII86250.1 - 1.1e-102 343.9 0.2 1.3e-102 343.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII86250.1 - 3.4e-11 42.9 6.6 2.2e-08 33.8 0.5 3.2 2 2 1 3 3 3 2 ADP-ribosylation factor family SNF2_N PF00176.23 KII86250.1 - 0.0016 17.2 0.1 0.0025 16.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain MMR_HSR1 PF01926.23 KII86250.1 - 0.0035 17.4 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KII86250.1 - 0.0037 17.5 0.4 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Flavodoxin_1 PF00258.25 KII86250.1 - 0.062 13.5 0.0 0.22 11.8 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin RsgA_GTPase PF03193.16 KII86250.1 - 0.13 12.1 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KII86250.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KII86250.1 - 0.44 9.9 8.6 0.77 9.1 0.6 2.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region ANAPC4_WD40 PF12894.7 KII86251.1 - 9.9e-07 29.0 0.3 0.012 15.9 0.2 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KII86251.1 - 0.058 12.4 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region CDC45 PF02724.14 KII86251.1 - 3.2 5.9 6.5 4.4 5.5 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SPO22 PF08631.10 KII86252.1 - 4.6e-53 180.5 12.9 4.8e-51 173.9 2.8 3.9 4 0 0 4 4 4 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KII86252.1 - 0.0091 16.2 2.8 0.051 13.8 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KII86252.1 - 0.033 14.3 0.9 12 6.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyclin PF08613.11 KII86254.1 - 4e-14 53.3 0.7 6.4e-14 52.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KII86254.1 - 1.4e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_S10 PF00450.22 KII86255.1 - 1.4e-111 373.9 0.1 1.7e-111 373.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Chs7 PF12271.8 KII86256.1 - 7e-117 389.9 18.5 8e-117 389.7 18.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone RAMP4 PF06624.12 KII86256.1 - 0.59 10.2 1.8 2.3 8.4 0.2 2.4 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Methyltransf_22 PF13383.6 KII86257.1 - 4.7e-21 75.5 0.0 7e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KII86257.1 - 4.5e-10 39.8 0.0 6.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DHC_N1 PF08385.12 KII86258.1 - 5.5e-127 424.8 10.4 2.9e-126 422.4 2.7 2.5 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 Aminotran_4 PF01063.19 KII86259.1 - 9.8e-27 94.3 0.0 1.4e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV 2-oxoacid_dh PF00198.23 KII86261.1 - 5.6e-47 160.2 0.0 1.4e-46 158.9 0.0 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KII86261.1 - 2.1e-18 65.9 0.1 4.2e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KII86261.1 - 3.3e-15 56.1 0.5 7.4e-15 55.0 0.5 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KII86261.1 - 3e-05 23.7 0.2 7.2e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KII86261.1 - 0.046 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KII86261.1 - 0.14 12.9 0.0 0.7 10.6 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein adh_short PF00106.25 KII86262.1 - 8e-20 71.1 2.5 2.2e-19 69.7 2.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86262.1 - 2.2e-08 34.0 5.2 4.7e-07 29.6 5.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86262.1 - 0.00025 21.0 3.6 0.0017 18.3 0.9 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KII86262.1 - 0.0031 17.0 0.1 0.16 11.4 0.2 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KII86262.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 KII86262.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.6 KII86262.1 - 0.1 12.5 0.6 0.25 11.2 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KII86262.1 - 0.11 11.9 0.1 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 KII86262.1 - 0.26 11.1 1.0 1.4 8.7 0.2 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SR-25 PF10500.9 KII86263.1 - 0.18 11.4 49.2 0.28 10.8 49.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein p450 PF00067.22 KII86264.1 - 2.1e-59 201.5 0.0 2.6e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII86265.1 - 8.8e-71 239.0 0.0 9.8e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII86266.1 - 6.2e-70 236.2 0.0 7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDKN3 PF05706.12 KII86267.1 - 0.00011 21.9 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 KII86267.1 - 0.00077 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII86267.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KII86267.1 - 0.034 14.1 0.1 0.097 12.6 0.1 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family Alpha-amylase PF00128.24 KII86268.1 - 3e-112 375.5 0.1 2.1e-111 372.8 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KII86268.1 - 1.9e-08 34.3 0.0 4.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain PHY PF00360.20 KII86268.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region PS_Dcarbxylase PF02666.15 KII86269.1 - 1.1e-69 234.0 0.0 3.3e-55 186.8 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase Rtf2 PF04641.12 KII86270.1 - 2.8e-76 256.4 0.5 3.4e-76 256.1 0.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KII86270.1 - 0.00053 19.7 0.2 0.088 12.6 0.0 2.5 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KII86270.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Med21 PF11221.8 KII86271.1 - 1e-29 103.7 7.2 1.3e-29 103.3 7.2 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Synaptobrevin PF00957.21 KII86271.1 - 0.061 13.1 1.0 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Synaptobrevin COG2 PF06148.11 KII86271.1 - 0.063 13.4 1.7 8.2 6.5 0.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med11 PF10280.9 KII86271.1 - 0.066 13.7 3.3 0.48 10.9 3.3 1.9 1 1 0 1 1 1 0 Mediator complex protein Nrap_D3 PF17404.2 KII86271.1 - 0.067 13.3 0.4 0.13 12.3 0.1 1.5 1 1 1 2 2 2 0 Nrap protein domain 3 Cep57_MT_bd PF06657.13 KII86271.1 - 0.13 12.7 8.9 0.29 11.6 1.9 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 KII86271.1 - 0.19 12.2 4.2 5.3 7.6 0.7 2.4 2 1 0 2 2 2 0 Cell division protein ZapB ApeA_NTD1 PF18862.1 KII86271.1 - 0.21 11.1 0.1 0.26 10.8 0.1 1.1 1 0 0 1 1 1 0 ApeA N-terminal domain 1 DUF3391 PF11871.8 KII86271.1 - 0.91 10.1 6.7 3.2 8.3 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3135 PF11333.8 KII86271.1 - 1 9.7 4.4 3.5 8.0 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) SseC PF04888.12 KII86271.1 - 1.5 8.4 5.7 4.9 6.7 0.4 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family ChaC PF04752.12 KII86273.1 - 1.1e-50 172.1 0.0 1.3e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein DUF4038 PF13204.6 KII86273.1 - 0.006 16.3 0.0 0.0083 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) DUF21 PF01595.20 KII86274.1 - 1.4e-29 103.1 0.1 2.3e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KII86274.1 - 2.3e-07 31.1 0.2 0.047 14.1 0.0 3.2 3 0 0 3 3 3 2 CBS domain tRNA_U5-meth_tr PF05958.11 KII86275.1 - 6.1e-12 45.2 0.0 7e-11 41.7 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KII86275.1 - 5e-07 29.5 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KII86275.1 - 7.2e-06 25.9 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII86275.1 - 1.9e-05 25.3 0.0 3.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KII86275.1 - 0.00068 19.3 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KII86275.1 - 0.0011 19.6 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KII86275.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KII86275.1 - 0.036 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Abhydrolase_1 PF00561.20 KII86276.1 - 4.7e-40 137.8 0.0 6.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII86276.1 - 0.024 15.2 8.3 0.045 14.3 8.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 KII86276.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase F-box-like PF12937.7 KII86278.1 - 3.5e-07 30.0 0.8 3.5e-07 30.0 0.8 2.1 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.28 KII86279.1 - 1.2e-13 50.2 7.2 5.5e-05 22.8 1.3 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII86279.1 - 3.4e-11 42.4 6.9 0.00016 21.5 1.3 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII86279.1 - 2.8e-07 30.2 7.2 0.065 13.5 1.6 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII86279.1 - 4.3e-07 30.1 0.4 0.00078 19.7 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII86279.1 - 7.8e-06 26.3 2.9 0.00092 19.7 0.0 3.0 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII86279.1 - 2.1e-05 24.9 1.6 0.052 14.4 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII86279.1 - 3.4e-05 24.4 2.0 0.12 13.1 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII86279.1 - 7.4e-05 23.1 4.1 0.75 10.6 0.1 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat GlutR_N PF05201.15 KII86279.1 - 0.00022 21.0 0.2 0.00029 20.6 0.2 1.2 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain TPR_11 PF13414.6 KII86279.1 - 0.0013 18.3 0.2 0.0013 18.3 0.2 3.1 3 1 0 3 3 3 1 TPR repeat DUF5588 PF17826.1 KII86279.1 - 0.0032 16.4 3.2 0.23 10.3 0.1 2.1 1 1 0 2 2 2 2 Family of unknown function (DUF5588) TPR_17 PF13431.6 KII86279.1 - 0.007 16.7 0.1 2.8 8.5 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII86279.1 - 0.0082 16.3 2.7 0.044 14.0 1.8 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 EzrA PF06160.12 KII86279.1 - 0.0084 14.3 1.1 0.012 13.8 1.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TPR_7 PF13176.6 KII86279.1 - 0.012 15.6 1.1 8.4 6.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KII86279.1 - 0.03 14.3 0.2 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Peptidase_C14 PF00656.22 KII86280.1 - 4.4e-56 190.6 0.0 7e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain tRNA-synt_1c PF00749.21 KII86282.1 - 9e-83 277.7 0.0 1.4e-82 277.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Baculo_ODV-E27 PF05314.11 KII86282.1 - 0.059 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 Alpha-amylase PF00128.24 KII86283.1 - 1.9e-61 208.5 0.1 2.6e-61 208.0 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KII86283.1 - 4.9e-11 42.8 0.1 1.2e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Chlorovi_GP_rpt PF06598.11 KII86283.1 - 1.3 9.2 3.8 11 6.2 0.4 2.9 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Cys_Met_Meta_PP PF01053.20 KII86285.1 - 3.4e-125 417.5 0.0 2e-124 415.0 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KII86285.1 - 0.0061 15.8 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 KII86285.1 - 0.011 14.3 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase VWA_3_C PF18571.1 KII86285.1 - 0.047 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain zf-UBR PF02207.20 KII86286.1 - 1.7e-16 60.1 17.1 1.7e-16 60.1 17.1 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KII86286.1 - 1.3e-11 44.1 0.1 3.6e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 KII86286.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL CtnDOT_TraJ PF07863.11 KII86286.1 - 0.19 12.4 0.0 0.48 11.1 0.0 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon TRAPP PF04051.16 KII86287.1 - 5.2e-37 126.8 0.0 6.6e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CAP_N PF01213.19 KII86287.1 - 0.43 10.0 1.1 0.77 9.2 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Alpha-amylase PF00128.24 KII86288.1 - 1.1e-58 199.4 0.3 1.9e-58 198.7 0.3 1.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KII86288.1 - 1e-13 51.3 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 KII86288.1 - 0.16 11.0 0.1 0.22 10.6 0.1 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain SNF2_N PF00176.23 KII86289.1 - 2.3e-49 168.0 0.0 4.2e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII86289.1 - 2.4e-14 53.6 0.0 5.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII86289.1 - 5.2e-07 29.8 0.0 9.9e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KII86289.1 - 2.8e-05 24.0 0.0 0.00016 21.5 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Glycophorin_A PF01102.18 KII86292.1 - 0.041 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A PCI PF01399.27 KII86293.1 - 1.4e-05 25.5 1.6 3e-05 24.5 0.6 2.0 2 1 0 2 2 2 1 PCI domain CSN7a_helixI PF18392.1 KII86293.1 - 0.0045 16.9 0.4 0.0093 15.9 0.4 1.6 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Med31 PF05669.12 KII86293.1 - 0.018 15.1 0.8 0.042 13.8 0.7 1.7 1 1 0 1 1 1 0 SOH1 DUF5595 PF18077.1 KII86293.1 - 0.034 14.2 0.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Lectin_N PF03954.14 KII86293.1 - 0.043 13.5 1.6 0.11 12.2 1.6 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Sipho_Gp157 PF05565.11 KII86294.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 Glyco_transf_25 PF01755.17 KII86295.1 - 2.1e-08 34.3 0.0 1.2e-06 28.6 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) OPT PF03169.15 KII86297.1 - 8.4e-180 599.4 60.0 7.9e-178 592.9 60.0 2.1 1 1 0 1 1 1 1 OPT oligopeptide transporter protein PRK PF00485.18 KII86298.1 - 1.5e-05 24.9 0.0 0.00015 21.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KII86298.1 - 0.00051 20.6 0.2 0.0045 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII86298.1 - 0.0049 17.0 0.6 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KII86298.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 KII86298.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KII86298.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 KII86298.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MFS_1 PF07690.16 KII86299.1 - 3e-30 105.3 28.5 8.7e-29 100.5 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3640 PF12342.8 KII86302.1 - 0.11 12.2 0.6 1.5 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) OPT PF03169.15 KII86303.1 - 2e-191 637.9 54.6 2.3e-191 637.7 54.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mt_ATP-synt_D PF05873.12 KII86304.1 - 0.013 15.3 2.1 0.021 14.7 2.1 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) FapA PF03961.13 KII86304.1 - 0.068 11.8 1.2 0.079 11.6 1.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laps PF10169.9 KII86304.1 - 7.5 7.1 9.7 2.9 8.5 6.5 2.0 2 1 0 2 2 2 0 Learning-associated protein zf-ANAPC11 PF12861.7 KII86305.1 - 3.7e-39 132.7 11.2 4.3e-39 132.5 11.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KII86305.1 - 7.1e-21 74.2 11.9 1.1e-20 73.7 11.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KII86305.1 - 0.0017 18.6 19.0 0.0073 16.6 16.4 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KII86305.1 - 0.16 11.9 13.6 0.76 9.7 13.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII86305.1 - 0.16 12.0 10.3 0.37 10.9 10.3 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KII86305.1 - 0.32 11.0 15.3 9.8 6.2 16.3 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII86305.1 - 5.7 6.9 18.4 1.1 9.1 11.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rgp1 PF08737.10 KII86306.1 - 7.5e-52 176.9 0.0 1.3e-51 176.2 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KII86306.1 - 0.026 15.0 0.0 4.1 7.9 0.0 2.9 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain PSP1 PF04468.12 KII86307.1 - 6.1e-30 103.3 1.8 9.6e-30 102.7 1.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-C2H2 PF00096.26 KII86309.1 - 1.5e-06 28.4 12.0 0.0011 19.4 2.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII86309.1 - 0.00014 22.1 7.2 0.0016 18.8 0.5 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 KII86309.1 - 0.0073 16.0 1.3 0.22 11.3 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain PknG_rubred PF16919.5 KII86309.1 - 0.011 15.9 0.3 0.011 15.9 0.3 2.4 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain zf-C2H2_4 PF13894.6 KII86309.1 - 0.023 15.5 9.6 0.82 10.7 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger SWIRM-assoc_2 PF16496.5 KII86309.1 - 0.71 8.7 4.1 1.1 8.1 4.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-C2HC_2 PF13913.6 KII86309.1 - 7.4 6.6 8.7 2.8 7.9 3.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type F-box-like PF12937.7 KII86311.1 - 1.4e-05 24.8 0.1 4.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like Bromodomain PF00439.25 KII86314.1 - 1.1e-19 70.3 0.0 1.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KII86314.1 - 3.5e-08 33.3 0.0 6.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 BAH domain DUF1479 PF07350.12 KII86315.1 - 8.5e-132 439.8 0.0 9.7e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KII86315.1 - 0.0027 18.0 0.0 0.13 12.4 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Pro_dh PF01619.18 KII86316.1 - 4.5e-52 177.4 0.0 1.4e-50 172.5 0.0 2.2 1 1 0 1 1 1 1 Proline dehydrogenase p450 PF00067.22 KII86317.1 - 9.1e-55 186.2 0.0 2.1e-54 185.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 peroxidase PF00141.23 KII86318.1 - 1.7e-30 106.4 0.0 2.7e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KII86318.1 - 2.6e-26 91.4 0.9 5.3e-26 90.4 0.9 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region SprT-like PF10263.9 KII86319.1 - 3e-28 97.9 0.5 4.6e-28 97.3 0.5 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KII86319.1 - 0.013 15.4 2.0 0.023 14.6 2.0 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 KII86319.1 - 0.12 12.5 2.0 0.24 11.6 2.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PUF PF00806.19 KII86320.1 - 2e-56 184.6 12.7 1.5e-07 30.7 0.1 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Atg14 PF10186.9 KII86321.1 - 4.4e-12 45.7 0.0 9.5e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KII86321.1 - 0.00066 18.7 0.0 0.93 8.3 0.0 3.0 3 0 0 3 3 3 2 Vacuolar protein sorting 38 Ribosomal_S14 PF00253.21 KII86323.1 - 3.5e-14 52.3 3.5 3.8e-14 52.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Glyco_trans_1_4 PF13692.6 KII86324.1 - 3e-09 37.4 0.0 7.6e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KII86324.1 - 1.9e-07 30.8 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KII86324.1 - 0.00021 21.3 0.3 0.00041 20.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KII86324.1 - 0.00029 21.3 0.5 0.00084 19.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KII86324.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Copper-fist PF00649.18 KII86326.1 - 1.8e-21 75.3 1.1 1.8e-21 75.3 1.1 2.3 2 0 0 2 2 2 1 Copper fist DNA binding domain F-box-like PF12937.7 KII86327.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII86327.1 - 0.01 16.3 2.3 9.4 6.8 0.0 4.8 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) UQ_con PF00179.26 KII86328.1 - 1.9e-27 95.6 0.0 2.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KII86328.1 - 6.5e-05 22.6 0.0 0.007 16.1 0.1 2.1 1 1 1 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 KII86328.1 - 0.0037 17.1 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain Porphobil_deam PF01379.20 KII86329.1 - 3.4e-70 235.7 0.0 4.3e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KII86329.1 - 2.1e-17 63.3 1.4 3.9e-17 62.4 1.4 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CobN-Mg_chel PF02514.16 KII86329.1 - 0.0011 16.8 0.0 0.002 16.0 0.0 1.3 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Nfu_N PF08712.11 KII86330.1 - 1.2e-29 102.2 0.0 3.3e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KII86330.1 - 1.6e-27 95.4 0.2 3e-27 94.6 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain BAR PF03114.18 KII86333.1 - 6.5e-38 130.7 2.1 1.1e-37 130.0 2.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KII86333.1 - 2.4e-15 55.8 0.1 4.2e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KII86333.1 - 1.4e-14 53.7 0.1 2.2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KII86333.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-C4H2 PF10146.9 KII86333.1 - 0.65 10.3 2.8 0.74 10.1 0.8 2.1 2 1 0 2 2 2 0 Zinc finger-containing protein P_C PF06640.11 KII86333.1 - 5.8 7.0 9.0 13 5.8 9.0 1.6 1 0 0 1 1 1 0 P protein C-terminus SBDS_C PF09377.10 KII86334.1 - 4.8e-37 126.5 0.6 7.5e-37 125.9 0.2 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 KII86334.1 - 2.6e-34 117.1 1.7 5e-34 116.2 1.7 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein BTB PF00651.31 KII86335.1 - 6.3e-07 29.6 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1810 PF08837.11 KII86335.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) F-box-like PF12937.7 KII86337.1 - 0.051 13.5 0.2 0.051 13.5 0.2 2.1 2 0 0 2 2 2 0 F-box-like DUF3417 PF11897.8 KII86337.1 - 0.2 12.2 0.6 0.5 10.8 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) Fe-S_biosyn PF01521.20 KII86338.1 - 1.1e-21 77.1 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SPRY PF00622.28 KII86341.1 - 8.6e-21 74.3 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KII86341.1 - 4e-13 49.5 0.0 5.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KII86341.1 - 0.0064 16.4 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 LisH gag-asp_proteas PF13975.6 KII86341.1 - 0.046 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1702 PF08012.11 KII86341.1 - 0.086 11.7 0.3 0.13 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) adh_short PF00106.25 KII86342.1 - 2.2e-47 161.1 1.4 6.1e-47 159.6 1.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86342.1 - 1.1e-46 159.3 1.7 2.1e-46 158.4 1.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86342.1 - 3.7e-11 43.3 0.2 6.5e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 KR domain UMP1 PF05348.11 KII86343.1 - 1.1e-32 112.7 0.0 1.5e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cullin PF00888.22 KII86345.1 - 0.0011 17.7 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family F-box-like PF12937.7 KII86350.1 - 1.4e-11 44.1 1.6 3.4e-11 42.9 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86350.1 - 0.019 14.8 1.2 0.43 10.5 1.2 2.8 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KII86350.1 - 0.074 13.5 7.5 0.62 10.6 0.1 4.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) DHO_dh PF01180.21 KII86351.1 - 3e-15 56.2 0.0 3.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.16 KII86352.1 - 1.2e-40 138.5 0.0 1.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SET PF00856.28 KII86353.1 - 9e-06 26.2 0.0 2.9e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 SET domain HMG_box PF00505.19 KII86354.1 - 4e-14 52.8 0.0 7.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII86354.1 - 2.5e-05 24.8 0.0 6.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain PARP PF00644.20 KII86355.1 - 3.6e-54 183.3 0.0 3.6e-54 183.3 0.0 3.0 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KII86355.1 - 9.4e-38 129.4 0.0 1.5e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KII86355.1 - 1.5e-21 76.2 0.1 4.2e-21 74.8 0.1 1.8 1 0 0 1 1 1 1 WGR domain TFIIE-A_C PF11521.8 KII86355.1 - 1.5 9.2 12.5 8.3 6.8 5.8 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha CENP-B_dimeris PF09026.10 KII86355.1 - 9.2 6.7 8.4 17 5.9 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFAP1 PF06991.11 KII86356.1 - 1.4e-67 227.8 28.2 1.4e-67 227.8 28.2 2.1 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 KII86356.1 - 0.091 12.9 2.8 0.18 11.9 2.8 1.5 1 1 0 1 1 1 0 Zinc knuckle RdRP PF05183.12 KII86357.1 - 4.8e-63 213.7 0.0 5.3e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 KII86358.1 - 3.7e-83 280.2 0.0 4.8e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2722 PF10846.8 KII86358.1 - 0.12 11.2 0.9 0.18 10.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 KII86358.1 - 0.36 10.5 3.3 0.61 9.7 3.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF688 PF05097.12 KII86358.1 - 1.4 8.0 3.8 0.92 8.6 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF688) NAD_binding_8 PF13450.6 KII86359.1 - 7.2e-13 48.6 0.0 2.4e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII86359.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase PhoR PF11808.8 KII86359.1 - 0.029 14.8 0.6 0.063 13.7 0.6 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR NAD_binding_9 PF13454.6 KII86359.1 - 0.03 14.3 0.1 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding GREB1 PF15782.5 KII86359.1 - 0.042 11.0 0.0 0.055 10.6 0.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FAD_binding_3 PF01494.19 KII86359.1 - 0.093 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KII86359.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KII86359.1 - 0.14 11.4 0.1 0.37 10.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 KII86359.1 - 0.16 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DNase_NucA_NucB PF14040.6 KII86360.1 - 6.6e-17 61.9 1.5 1.1e-16 61.2 1.5 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB RseC_MucC PF04246.12 KII86361.1 - 0.075 13.0 0.2 0.075 13.0 0.2 3.0 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC UPF0242 PF06785.11 KII86361.1 - 0.23 11.6 0.7 0.43 10.7 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ComA PF02679.15 KII86362.1 - 1.6e-78 263.5 0.0 1.8e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) NmrA PF05368.13 KII86363.1 - 6.3e-16 58.6 0.1 8.6e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86363.1 - 8.9e-07 29.0 0.4 2.1e-06 27.8 0.5 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KII86363.1 - 1.8e-05 24.8 0.3 3.3e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KII86363.1 - 0.00016 21.2 0.5 0.00026 20.5 0.5 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KII86363.1 - 0.00026 21.3 0.2 0.00048 20.4 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 KII86363.1 - 0.011 15.4 0.2 0.058 13.0 0.2 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KII86363.1 - 0.025 14.6 0.2 0.05 13.6 0.2 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 KII86363.1 - 0.033 14.3 0.8 0.16 12.1 0.7 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 KII86363.1 - 0.07 13.8 0.7 0.11 13.2 0.7 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KII86363.1 - 0.083 13.7 0.4 0.13 13.1 0.4 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 KII86363.1 - 0.19 12.0 1.0 0.38 11.0 0.6 1.7 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.10 KII86363.1 - 0.39 10.6 2.0 0.93 9.4 2.0 1.5 1 1 0 1 1 1 0 KR domain SNF2_N PF00176.23 KII86364.1 - 1.5e-70 237.7 0.5 5.1e-70 235.9 0.5 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.13 KII86364.1 - 4e-20 71.9 10.8 4e-20 71.9 10.8 3.3 3 0 0 3 3 3 1 HSA Bromodomain PF00439.25 KII86364.1 - 1.9e-19 69.5 0.2 5e-19 68.2 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KII86364.1 - 8.4e-19 68.0 0.1 3.8e-17 62.6 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain QLQ PF08880.11 KII86364.1 - 3.2e-14 52.4 0.2 9.3e-14 50.9 0.2 1.9 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 KII86364.1 - 2.8e-11 43.9 0.3 2.8e-11 43.9 0.3 4.3 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KII86364.1 - 7.2e-09 35.9 0.2 3.9e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NADPH_Ox PF08414.10 KII86364.1 - 0.071 13.5 1.2 0.2 12.0 1.2 1.8 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Ku PF02735.16 KII86366.1 - 4.6e-29 101.6 0.0 2e-28 99.5 0.1 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KII86366.1 - 8.4e-24 84.0 0.0 1.6e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 KII86366.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KII86366.1 - 0.00021 21.6 0.0 0.00053 20.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KII86366.1 - 0.0027 18.3 0.0 0.013 16.1 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 KII86366.1 - 0.86 10.3 0.0 0.86 10.3 0.0 3.2 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm DNase_NucA_NucB PF14040.6 KII86367.1 - 3.7e-15 56.3 2.4 5.8e-15 55.7 2.4 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Dala_Dala_lig_N PF01820.21 KII86368.1 - 0.082 13.4 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus NmrA PF05368.13 KII86369.1 - 7.2e-15 55.2 0.0 9.4e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86369.1 - 1.9e-05 24.6 0.4 5.5e-05 23.1 0.4 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KII86369.1 - 0.00015 22.0 0.0 0.00022 21.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KII86369.1 - 0.00045 19.8 0.1 0.00064 19.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KII86369.1 - 0.00048 20.2 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KII86369.1 - 0.02 14.4 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DapB_N PF01113.20 KII86369.1 - 0.025 14.7 0.1 0.049 13.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 KII86369.1 - 0.028 14.7 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KII86369.1 - 0.047 13.6 0.2 0.078 12.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KII86369.1 - 0.15 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_Gly3P_dh_N PF01210.23 KII86369.1 - 0.18 11.8 0.2 4.9 7.1 0.3 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.13 KII86370.1 - 7.9e-17 61.6 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86370.1 - 3.2e-06 27.2 0.0 1.6e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KII86370.1 - 3.6e-05 23.8 0.0 8.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KII86370.1 - 0.00016 21.2 0.1 0.00026 20.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KII86370.1 - 0.00043 20.5 0.8 0.087 13.1 0.2 2.4 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KII86370.1 - 0.0016 18.7 0.1 0.003 17.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KII86370.1 - 0.017 15.0 0.5 0.033 14.1 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 KII86370.1 - 0.03 14.4 0.3 0.074 13.2 0.2 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 KII86370.1 - 0.033 15.0 0.1 0.055 14.3 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PglD_N PF17836.1 KII86370.1 - 0.093 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain Gp_dh_N PF00044.24 KII86370.1 - 0.1 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NmrA PF05368.13 KII86371.1 - 2.2e-20 73.2 0.2 3e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86371.1 - 1.1e-06 28.7 0.7 1.9e-06 27.9 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KII86371.1 - 1.1e-05 25.5 0.1 2.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KII86371.1 - 0.00032 20.9 0.3 0.00059 20.1 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KII86371.1 - 0.00035 20.1 0.2 0.00052 19.5 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KII86371.1 - 0.0029 17.7 1.2 0.016 15.3 1.2 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 KII86371.1 - 0.028 14.8 0.1 0.075 13.4 0.1 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KII86371.1 - 0.036 13.9 0.3 0.066 13.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglD_N PF17836.1 KII86371.1 - 0.086 13.5 0.1 0.2 12.3 0.1 1.7 1 0 0 1 1 1 0 PglD N-terminal domain Aldolase PF01081.19 KII86371.1 - 0.12 11.8 0.3 0.19 11.1 0.3 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase GFO_IDH_MocA PF01408.22 KII86371.1 - 0.13 13.1 0.3 0.24 12.3 0.3 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 KII86371.1 - 0.15 12.3 0.3 0.33 11.2 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain Y_phosphatase PF00102.27 KII86372.1 - 9.9e-54 182.4 0.0 2.8e-46 158.0 0.0 2.6 2 1 0 2 2 2 2 Protein-tyrosine phosphatase NmrA PF05368.13 KII86372.1 - 4.8e-19 68.8 0.0 8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Rhodanese PF00581.20 KII86372.1 - 1.8e-06 28.4 0.0 5.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 KII86372.1 - 1.3e-05 25.5 0.0 4.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KII86372.1 - 2.4e-05 24.3 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding DSPc PF00782.20 KII86372.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CbiJ PF02571.14 KII86372.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK DUF5022 PF16425.5 KII86372.1 - 0.038 13.5 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) Epimerase PF01370.21 KII86372.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Y_phosphatase3 PF13350.6 KII86372.1 - 0.053 13.5 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Shikimate_DH PF01488.20 KII86372.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KII86373.1 - 4.1e-19 69.1 0.1 9.9e-19 67.8 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KII86373.1 - 0.0065 16.7 2.2 0.17 12.1 0.2 2.4 1 1 1 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KII86373.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.6 1 1 1 2 2 2 0 NAD(P)H-binding DUF5022 PF16425.5 KII86373.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5022) NmrA PF05368.13 KII86374.1 - 2.6e-11 43.6 0.0 3.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86374.1 - 1.6e-06 28.1 0.0 7.4e-06 26.0 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KII86374.1 - 0.00024 21.3 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KII86374.1 - 0.00035 20.1 0.0 0.00079 19.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KII86375.1 - 1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII86375.1 - 5.7e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KII86375.1 - 0.036 14.3 0.1 0.097 12.9 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Asparaginase_C PF17763.1 KII86375.1 - 0.084 13.1 1.0 28 5.0 0.0 3.1 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain DUF883 PF05957.13 KII86376.1 - 0.16 12.6 5.7 0.13 12.9 3.8 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Peptidase_C27 PF05407.12 KII86376.1 - 0.26 11.4 7.0 0.38 10.8 7.0 1.3 1 0 0 1 1 1 0 Rubella virus endopeptidase YtxH PF12732.7 KII86376.1 - 2.1 9.0 11.5 74 4.0 11.5 2.2 1 1 0 1 1 1 0 YtxH-like protein UPF0182 PF03699.13 KII86377.1 - 1.3 7.0 3.4 2.1 6.4 3.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Las1 PF04031.13 KII86378.1 - 4.5e-48 163.2 0.5 1.4e-47 161.6 0.5 1.8 2 0 0 2 2 2 1 Las1-like DUF4982 PF16355.5 KII86379.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4982) Ysc84 PF04366.12 KII86380.1 - 3.2e-35 120.7 0.2 5.6e-35 119.9 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KII86380.1 - 6.1e-17 61.0 0.1 1.4e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII86380.1 - 9.4e-15 54.0 0.0 9.3e-14 50.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KII86380.1 - 2.5e-14 52.8 0.2 2.1e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain ABC_membrane PF00664.23 KII86381.1 - 1.7e-41 142.7 26.1 2.2e-23 83.3 10.0 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII86381.1 - 2.9e-38 131.5 0.0 2.9e-24 86.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KII86381.1 - 2e-08 34.8 0.4 0.0015 19.0 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KII86381.1 - 1.1e-05 25.1 0.1 0.11 12.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KII86381.1 - 2.2e-05 24.0 4.1 0.28 10.6 0.0 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII86381.1 - 4e-05 24.2 2.0 0.0062 17.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KII86381.1 - 4.8e-05 23.3 1.7 0.16 11.7 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII86381.1 - 0.00048 19.8 0.3 1 9.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 KII86381.1 - 0.0016 18.0 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KII86381.1 - 0.0024 17.9 0.3 0.37 10.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KII86381.1 - 0.0042 16.2 0.1 0.44 9.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KII86381.1 - 0.0052 17.1 0.8 1.7 8.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KII86381.1 - 0.0084 16.2 0.5 1.4 9.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.17 KII86381.1 - 0.012 15.4 0.0 2.4 7.9 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KII86381.1 - 0.027 14.4 0.4 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 KII86381.1 - 0.036 14.2 1.2 0.19 11.8 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain OB_RNB PF08206.11 KII86381.1 - 0.046 13.4 0.0 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain AAA_15 PF13175.6 KII86381.1 - 0.05 13.3 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KII86381.1 - 0.053 12.9 0.1 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 KII86381.1 - 0.054 13.5 1.2 8.2 6.4 0.0 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 KII86381.1 - 0.059 13.1 0.9 13 5.5 0.4 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 KII86381.1 - 0.12 12.8 1.6 0.43 11.0 0.1 2.7 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 KII86381.1 - 0.18 10.6 0.1 2.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 KII86381.1 - 0.21 12.0 0.0 17 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DLH PF01738.18 KII86382.1 - 3.5e-12 46.4 0.1 4.8e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Prenylcys_lyase PF07156.14 KII86384.1 - 6.2e-72 242.7 0.0 8.3e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 KII86384.1 - 3.6e-12 46.3 0.1 1.2e-11 44.6 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII86384.1 - 1.5e-10 41.1 0.1 4e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII86384.1 - 9.4e-08 32.0 0.6 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII86384.1 - 0.0096 15.2 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII86384.1 - 0.045 13.7 0.1 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KII86384.1 - 0.23 10.1 0.4 9.6 4.8 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Ammonium_transp PF00909.21 KII86385.1 - 2.6e-110 368.8 26.5 3.1e-110 368.6 26.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family NAD_binding_10 PF13460.6 KII86386.1 - 6.5e-31 107.6 2.0 7.2e-31 107.5 2.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII86386.1 - 1.4e-11 44.4 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KII86386.1 - 4e-08 33.0 0.2 6.4e-08 32.4 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KII86386.1 - 6.1e-06 26.5 0.0 9.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KII86386.1 - 0.0015 18.0 0.2 0.0025 17.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 KII86386.1 - 0.0016 19.0 0.3 0.0052 17.3 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KII86386.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 KII86386.1 - 0.026 13.5 0.0 0.045 12.7 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KII86386.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP11 PF06644.11 KII86387.1 - 2.9e-81 273.2 0.0 3.4e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein DUF5333 PF17267.2 KII86387.1 - 0.19 12.0 0.6 0.33 11.2 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5333) SKG6 PF08693.10 KII86388.1 - 0.00045 19.6 3.5 0.00045 19.6 3.5 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KII86388.1 - 0.017 14.9 1.0 0.017 14.9 1.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 KII86388.1 - 0.1 12.4 0.5 0.19 11.5 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 KII86388.1 - 0.12 11.1 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E BPL_LplA_LipB PF03099.19 KII86389.1 - 7.3e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.23 KII86390.1 - 1.5e-46 159.3 11.3 5.6e-46 157.4 11.3 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII86390.1 - 0.00077 19.7 1.0 0.0063 16.8 0.1 2.4 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII86390.1 - 0.012 15.4 0.5 0.053 13.3 0.0 2.3 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KII86390.1 - 0.042 14.5 1.0 4.8 7.9 0.1 2.9 2 0 0 2 2 2 0 Aspartyl protease DUF5016 PF16408.5 KII86391.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5016) p450 PF00067.22 KII86392.1 - 1.9e-53 181.9 0.0 2.2e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 KII86393.1 - 3.2e-29 102.1 0.4 3.6e-29 101.9 0.4 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII86393.1 - 3.9e-12 46.2 0.1 5.1e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KII86393.1 - 1e-07 31.7 0.2 2.9e-07 30.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII86393.1 - 0.00028 20.0 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KII86393.1 - 0.00036 20.0 0.1 0.0006 19.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KII86393.1 - 0.00039 20.7 0.3 0.0007 19.9 0.3 1.5 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain LpxI_N PF17930.1 KII86393.1 - 0.0045 16.9 0.5 0.87 9.5 0.2 2.3 2 0 0 2 2 2 1 LpxI N-terminal domain NAD_binding_2 PF03446.15 KII86393.1 - 0.0092 16.2 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII86393.1 - 0.0094 16.5 0.6 0.046 14.3 0.6 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KII86393.1 - 0.031 14.2 0.2 0.38 10.7 0.2 2.1 2 0 0 2 2 2 0 KR domain ADH_zinc_N PF00107.26 KII86393.1 - 0.065 13.2 0.8 0.13 12.2 0.4 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 KII86393.1 - 0.11 11.6 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KII86393.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TauD PF02668.16 KII86394.1 - 9e-44 150.3 0.0 1.3e-43 149.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 1-cysPrx_C PF10417.9 KII86394.1 - 0.14 12.0 0.2 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.32 KII86395.1 - 1.7e-28 98.2 7.6 3e-05 24.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 KII86395.1 - 2e-07 30.1 0.0 0.0015 17.2 0.0 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 HEPN_LA2681 PF18733.1 KII86395.1 - 0.032 13.5 1.8 0.048 13.0 1.8 1.2 1 0 0 1 1 1 0 LA2681-like HEPN HAP1_N PF04849.13 KII86395.1 - 0.098 11.8 8.4 0.15 11.2 8.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region EzrA PF06160.12 KII86395.1 - 0.29 9.3 5.8 0.41 8.8 5.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DivIC PF04977.15 KII86395.1 - 0.56 10.0 2.4 1.8 8.4 1.9 2.1 2 0 0 2 2 2 0 Septum formation initiator HNH_2 PF13391.6 KII86397.1 - 0.032 14.4 0.4 0.11 12.6 0.4 1.9 1 0 0 1 1 1 0 HNH endonuclease BC10 PF06726.12 KII86400.1 - 1.8e-08 34.5 14.0 1.8e-08 34.5 14.0 1.8 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 CS PF04969.16 KII86401.1 - 1.1e-06 29.5 0.0 2.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KII86401.1 - 1.4 9.5 14.3 2.2 8.9 14.3 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region F-box-like PF12937.7 KII86403.1 - 1.7e-09 37.4 1.7 5.8e-09 35.7 0.1 2.5 2 1 0 2 2 2 1 F-box-like MAD PF05557.13 KII86403.1 - 0.19 10.0 0.8 0.26 9.6 0.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein F-box PF00646.33 KII86403.1 - 7.3 6.6 7.8 12 5.9 2.7 3.5 2 1 1 3 3 3 0 F-box domain HAD_2 PF13419.6 KII86404.1 - 4e-17 62.9 0.0 5e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII86404.1 - 7e-10 38.8 0.1 5.4e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KII86404.1 - 5.1e-05 23.7 0.0 0.00011 22.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HNH_2 PF13391.6 KII86407.1 - 0.039 14.1 2.3 0.074 13.2 0.2 2.5 2 1 0 2 2 2 0 HNH endonuclease ABC_membrane PF00664.23 KII86412.1 - 1.6e-45 155.9 26.9 2.6e-22 79.8 1.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KII86412.1 - 9.3e-35 120.1 0.0 4.3e-18 66.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KII86412.1 - 1.2e-06 28.6 0.7 0.088 12.6 0.1 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII86412.1 - 3.6e-06 26.6 0.5 0.46 9.9 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII86412.1 - 4e-06 27.3 0.0 0.067 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KII86412.1 - 4.9e-06 27.2 0.3 0.0016 19.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII86412.1 - 2.5e-05 24.0 0.0 0.043 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII86412.1 - 0.00016 21.3 0.3 0.63 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KII86412.1 - 0.00026 20.2 0.0 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KII86412.1 - 0.00058 19.9 0.3 0.52 10.4 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII86412.1 - 0.0014 18.5 0.1 0.68 9.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KII86412.1 - 0.0038 17.5 0.0 0.94 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KII86412.1 - 0.011 15.8 0.5 0.13 12.3 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 KII86412.1 - 0.012 14.5 0.1 0.42 9.4 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 KII86412.1 - 0.018 14.6 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KII86412.1 - 0.02 14.6 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KII86412.1 - 0.022 14.8 0.5 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 KII86412.1 - 0.024 14.5 0.1 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KII86412.1 - 0.026 13.9 0.1 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 KII86412.1 - 0.039 13.7 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KII86412.1 - 0.043 13.8 0.1 6 6.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KII86412.1 - 0.044 14.2 0.1 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KII86412.1 - 0.055 13.2 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain L51_S25_CI-B8 PF05047.16 KII86414.1 - 8.1e-08 32.1 0.5 1.3e-07 31.4 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Romo1 PF10247.9 KII86416.1 - 1.5e-24 86.1 9.4 2.1e-24 85.7 9.4 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.14 KII86417.1 - 4.4e-27 95.1 3.6 9.4e-27 94.1 3.6 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KII86417.1 - 1.3e-09 37.8 6.7 1.8e-09 37.3 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII86417.1 - 6.5e-08 32.3 9.0 9.7e-08 31.8 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII86417.1 - 1.6e-07 31.6 11.6 2.4e-07 30.9 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII86417.1 - 3.7e-07 29.9 7.8 5.9e-07 29.2 7.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KII86417.1 - 4.5e-07 29.6 9.5 7.1e-07 29.0 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII86417.1 - 5.6e-06 26.2 9.3 8.6e-06 25.6 9.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII86417.1 - 6.2e-06 26.1 5.0 1.7e-05 24.8 5.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KII86417.1 - 4.1e-05 23.8 7.3 8.2e-05 22.8 7.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KII86417.1 - 0.0084 16.2 9.9 0.016 15.3 9.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KII86417.1 - 0.01 15.8 1.7 0.019 15.0 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 KII86417.1 - 0.14 12.3 2.8 0.22 11.6 2.8 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 KII86417.1 - 0.58 10.3 6.5 1.1 9.5 6.5 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KII86417.1 - 0.8 9.6 5.1 1.4 8.9 5.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KII86417.1 - 0.93 9.3 8.6 1.6 8.6 8.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KII86417.1 - 2.2 8.6 7.6 4.7 7.5 7.6 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 KII86417.1 - 5.3 6.9 6.9 13 5.6 6.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger LSM PF01423.22 KII86418.1 - 7.3e-14 51.2 0.3 9.9e-14 50.8 0.2 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KII86418.1 - 0.0063 16.1 0.2 0.011 15.4 0.2 1.4 1 0 0 1 1 1 1 Hfq protein AAA_6 PF12774.7 KII86419.1 - 3.8e-125 417.2 0.0 2.2e-123 411.4 0.0 3.4 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KII86419.1 - 7e-116 387.6 9.7 7e-116 387.6 9.7 2.7 3 1 1 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KII86419.1 - 5.6e-73 244.7 0.5 5.6e-73 244.7 0.5 4.5 4 1 1 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 KII86419.1 - 8e-68 228.6 0.0 2.1e-67 227.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KII86419.1 - 5.7e-43 146.5 0.0 5.8e-36 123.7 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 KII86419.1 - 1.8e-38 132.5 3.9 2.8e-38 131.8 3.9 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 KII86419.1 - 1.4e-35 122.5 0.0 6.2e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KII86419.1 - 1.8e-30 105.5 0.0 2.1e-29 102.0 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 KII86419.1 - 3.6e-29 101.5 0.1 1.5e-12 47.7 0.0 6.7 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KII86419.1 - 1.3e-18 67.3 0.5 4.8e-17 62.3 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KII86419.1 - 3.2e-13 50.3 0.0 0.00097 19.6 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII86419.1 - 1.5e-12 48.0 0.5 0.0057 16.9 0.0 5.8 4 1 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KII86419.1 - 9.8e-09 35.5 7.5 0.27 11.4 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 KII86419.1 - 1e-08 35.7 0.0 0.6 10.5 0.0 6.2 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 KII86419.1 - 2.3e-07 31.4 1.4 0.1 13.1 0.0 5.4 5 0 0 5 5 4 2 AAA domain FtsK_SpoIIIE PF01580.18 KII86419.1 - 9.7e-06 25.1 0.0 0.33 10.3 0.0 3.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family T2SSE PF00437.20 KII86419.1 - 3.4e-05 23.1 0.0 0.013 14.6 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 KII86419.1 - 0.00013 22.1 2.3 0.00039 20.6 0.0 3.0 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 KII86419.1 - 0.00013 22.3 3.6 0.28 11.5 0.0 5.2 5 0 0 5 5 5 1 AAA domain AAA_30 PF13604.6 KII86419.1 - 0.00019 21.2 0.9 23 4.6 0.0 4.7 5 0 0 5 5 4 0 AAA domain Mg_chelatase PF01078.21 KII86419.1 - 0.00033 20.1 3.9 0.6 9.4 0.0 3.7 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KII86419.1 - 0.0008 19.2 1.4 0.71 9.6 0.0 4.5 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 KII86419.1 - 0.0013 18.4 0.1 0.79 9.5 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 KII86419.1 - 0.0013 17.7 0.1 3.1 6.6 0.0 3.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KII86419.1 - 0.0035 17.1 0.6 21 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 KII86419.1 - 0.0091 16.4 0.0 43 4.5 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.6 KII86419.1 - 0.0094 15.5 0.1 0.58 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KII86419.1 - 0.0097 16.4 2.6 10 6.6 0.0 4.8 5 0 0 5 5 4 0 ABC transporter TsaE PF02367.17 KII86419.1 - 0.019 14.9 0.4 15 5.6 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 KII86419.1 - 0.057 13.3 0.1 23 4.8 0.0 4.3 6 0 0 6 6 4 0 Rad17 P-loop domain PduV-EutP PF10662.9 KII86419.1 - 0.1 12.4 0.4 11 5.8 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 KII86419.1 - 0.1 12.3 0.2 3.2 7.5 0.0 3.1 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KII86419.1 - 0.11 12.5 0.1 32 4.5 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KII86419.1 - 0.22 11.1 2.2 39 3.8 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KII86419.1 - 0.38 10.7 4.5 37 4.2 0.1 4.6 5 0 0 5 5 3 0 NACHT domain AAA_11 PF13086.6 KII86419.1 - 2.3 7.9 14.2 1.2 8.8 0.0 4.2 5 0 0 5 5 4 0 AAA domain Spc7 PF08317.11 KII86419.1 - 3.1 6.6 32.6 0.011 14.6 12.4 3.6 3 0 0 3 3 3 0 Spc7 kinetochore protein Dynein_C PF18199.1 KII86420.1 - 2.8e-33 115.5 0.0 3.1e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain GHMP_kinases_N PF00288.26 KII86422.1 - 5e-09 36.3 0.1 1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KII86422.1 - 0.0039 17.5 0.1 0.012 15.9 0.1 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal DUF707 PF05212.12 KII86424.1 - 0.12 11.6 0.2 0.14 11.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF707) Metallothio_Cad PF07846.11 KII86425.1 - 0.038 14.1 1.7 9.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Metallothionein family LRR_4 PF12799.7 KII86426.1 - 0.031 14.7 3.8 41 4.8 0.2 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) HNH_2 PF13391.6 KII86427.1 - 0.031 14.4 0.3 0.092 12.9 0.3 1.7 1 0 0 1 1 1 0 HNH endonuclease Beta-lactamase PF00144.24 KII86430.1 - 1.1e-44 153.0 4.3 2.6e-44 151.8 1.9 2.2 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 KII86430.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Glutaminase PF04960.15 KII86430.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 Glutaminase Mg_trans_NIPA PF05653.14 KII86431.1 - 6.2e-22 78.1 11.0 6.3e-11 41.9 2.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KII86431.1 - 0.018 15.2 5.4 0.018 15.2 5.4 2.9 3 0 0 3 3 3 0 EamA-like transporter family PUNUT PF16913.5 KII86431.1 - 0.57 9.4 6.4 0.063 12.5 1.6 1.9 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport DENN PF02141.21 KII86432.1 - 2.2e-19 70.1 0.0 4.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain ADIP PF11559.8 KII86432.1 - 0.0042 17.2 7.9 0.0091 16.1 7.9 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KII86432.1 - 0.032 14.5 12.6 0.066 13.4 12.6 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SLATT_1 PF18181.1 KII86432.1 - 0.039 13.9 2.4 0.08 12.9 2.4 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 APG6_N PF17675.1 KII86432.1 - 0.091 13.3 9.1 0.19 12.2 9.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region MalF_P2 PF14785.6 KII86432.1 - 0.11 12.5 2.6 0.2 11.7 2.6 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Lum_binding PF00677.17 KII86432.1 - 0.16 12.0 0.1 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Lumazine binding domain FAM184 PF15665.5 KII86432.1 - 0.16 11.7 12.5 0.28 10.9 12.5 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Tup_N PF08581.10 KII86432.1 - 0.45 10.9 10.0 0.19 12.1 6.1 2.2 2 0 0 2 2 2 0 Tup N-terminal FapA PF03961.13 KII86432.1 - 0.68 8.5 4.1 1.1 7.8 4.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF948 PF06103.11 KII86432.1 - 0.69 10.2 3.3 1.6 9.1 2.8 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 KII86432.1 - 0.96 9.0 15.1 0.81 9.2 12.9 1.7 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 KII86432.1 - 1.2 8.4 9.2 2.5 7.4 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOGA PF11365.8 KII86432.1 - 1.6 9.9 8.3 3.7 8.7 7.1 2.1 1 1 1 2 2 2 0 Protein SOGA OmpH PF03938.14 KII86432.1 - 1.9 8.8 19.1 2.1 8.7 17.9 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 KII86432.1 - 4.6 7.5 7.0 3.4 8.0 3.2 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 KII86432.1 - 4.7 6.2 9.3 8.1 5.4 9.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 KII86432.1 - 7.8 7.2 10.4 2.1e+02 2.6 5.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 KII86432.1 - 8 6.5 7.4 43 4.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HyaE PF07449.11 KII86433.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Caskin-Pro-rich PF16907.5 KII86433.1 - 0.39 11.3 9.2 0.52 10.9 1.2 3.2 3 0 0 3 3 3 0 Proline rich region of Caskin proteins DUF4366 PF14283.6 KII86434.1 - 0.19 11.8 2.4 7.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) CCDC24 PF15669.5 KII86434.1 - 0.19 11.5 10.3 2.8 7.8 1.4 3.1 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family VPS13_mid_rpt PF16910.5 KII86435.1 - 1.2e-100 335.8 12.3 3.6e-97 324.4 2.2 4.6 3 1 1 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KII86435.1 - 9.7e-84 280.8 0.8 9.2e-80 267.8 0.0 3.6 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KII86435.1 - 5.8e-69 231.4 9.6 3.1e-66 222.6 0.1 3.4 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KII86435.1 - 1.1e-60 205.3 0.0 4e-58 196.9 0.0 3.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KII86435.1 - 2.7e-29 101.7 0.1 9e-29 100.0 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KII86435.1 - 5.8e-09 36.2 0.0 1.8e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 KII86435.1 - 0.0015 17.5 5.2 0.043 12.7 0.0 3.0 4 0 0 4 4 4 2 Golgi-body localisation protein domain ELO PF01151.18 KII86437.1 - 6e-59 199.6 13.5 7.2e-59 199.3 13.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DHHC PF01529.20 KII86437.1 - 0.65 10.1 0.0 0.65 10.1 0.0 3.2 3 1 0 3 3 3 0 DHHC palmitoyltransferase SNARE_assoc PF09335.11 KII86437.1 - 7.7 7.0 12.3 0.54 10.8 1.3 3.5 3 1 1 4 4 4 0 SNARE associated Golgi protein RasGAP PF00616.19 KII86438.1 - 4.9e-27 95.0 0.0 2.8e-19 69.7 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KII86438.1 - 4.2e-12 46.3 0.0 7.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain CBP_BcsS PF17036.5 KII86438.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS O-FucT PF10250.9 KII86439.1 - 4.4e-11 43.1 0.0 1.7e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TT1725 PF18324.1 KII86440.1 - 0.0081 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein TT1725 MPC PF03650.13 KII86441.1 - 1.3e-34 118.7 0.1 1.6e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DNA_ligase_A_M PF01068.21 KII86442.1 - 3.7e-64 216.1 0.1 5.8e-64 215.5 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KII86442.1 - 4.2e-43 147.7 1.4 5.3e-43 147.3 0.2 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KII86442.1 - 1e-25 90.2 0.1 2.9e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 KII86442.1 - 0.024 14.7 0.2 8.4 6.5 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Aa_trans PF01490.18 KII86443.1 - 4.3e-27 94.8 29.2 5.6e-27 94.5 29.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein OppC_N PF12911.7 KII86444.1 - 0.003 17.5 1.1 0.0075 16.2 1.1 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C ResB PF05140.14 KII86444.1 - 0.0031 16.3 1.0 0.0041 15.9 1.0 1.3 1 0 0 1 1 1 1 ResB-like family PMP1_2 PF08114.11 KII86444.1 - 0.14 11.9 1.3 0.25 11.1 1.3 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Erf4 PF10256.9 KII86445.1 - 2.9e-27 95.1 0.0 4e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.28 KII86446.1 - 9.1e-49 161.4 24.5 2.9e-07 30.0 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KII86446.1 - 4.1e-46 151.4 19.0 2.2e-05 24.2 0.5 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KII86446.1 - 1.2e-35 118.7 11.0 0.00053 20.0 1.6 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KII86446.1 - 4e-28 97.8 10.8 1.2e-06 29.0 0.0 7.7 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 KII86446.1 - 3.5e-24 83.4 12.1 0.002 18.8 0.1 9.4 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 KII86446.1 - 1.9e-22 79.3 15.1 0.00018 21.8 1.0 7.8 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KII86446.1 - 1.2e-21 77.0 15.9 0.00051 20.5 0.4 7.5 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KII86446.1 - 2.7e-21 74.0 9.5 0.28 11.3 0.2 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.6 KII86446.1 - 9.3e-21 73.0 10.4 0.085 13.5 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 KII86446.1 - 1.1e-19 69.3 22.6 0.00089 19.5 0.3 9.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KII86446.1 - 2e-19 69.0 33.6 3.8e-06 26.5 0.4 10.0 7 3 4 11 11 11 6 TPR repeat TPR_9 PF13371.6 KII86446.1 - 1.6e-12 47.3 15.6 0.018 15.2 0.7 6.8 2 2 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KII86446.1 - 7.9e-09 35.6 9.0 5.3e-05 23.4 0.9 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KII86446.1 - 5.3e-07 29.1 7.0 0.019 14.2 0.6 4.9 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KII86446.1 - 0.00052 19.5 2.7 0.015 14.7 0.3 2.6 2 1 1 3 3 3 1 MalT-like TPR region ChAPs PF09295.10 KII86446.1 - 0.0035 16.4 0.7 2.2 7.2 0.1 2.5 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 KII86446.1 - 0.0037 16.7 8.5 0.18 11.2 0.3 4.0 2 2 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 KII86446.1 - 0.004 16.9 8.0 0.059 13.1 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KII86446.1 - 0.0067 16.7 2.8 0.019 15.2 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 KII86446.1 - 0.0071 16.1 0.3 0.78 9.4 0.0 3.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF4919 PF16266.5 KII86446.1 - 0.025 14.5 0.2 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 KII86446.1 - 0.053 13.5 19.9 2.4 8.2 1.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 KII86446.1 - 2.2 8.7 9.2 6.2 7.3 0.5 3.9 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KII86446.1 - 2.4 8.2 13.0 56 3.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat 4F5 PF04419.14 KII86450.1 - 7.8e-05 23.5 31.5 0.02 15.7 31.5 2.6 1 1 0 1 1 1 1 4F5 protein family AP-5_subunit_s1 PF15001.6 KII86450.1 - 4.3 7.3 7.0 4.6 7.2 7.0 1.0 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 stn_TNFRSF12A PF12191.8 KII86451.1 - 0.35 11.1 1.6 0.35 11.1 0.4 1.7 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Brr6_like_C_C PF10104.9 KII86452.1 - 1.9e-45 153.9 1.8 2.4e-45 153.5 1.8 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Vps54 PF07928.12 KII86452.1 - 0.21 12.1 0.4 1.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Vps54-like protein Vpu PF00558.19 KII86452.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Vpu protein CLP_protease PF00574.23 KII86453.1 - 7.6e-71 237.8 0.0 9.4e-71 237.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease ECH_1 PF00378.20 KII86453.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Caprin-1_C PF12287.8 KII86455.1 - 2.1 8.4 9.0 0.47 10.6 4.9 1.6 1 1 1 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term CAV_VP3 PF04771.12 KII86455.1 - 9 6.5 10.7 1.6 8.9 2.9 2.3 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein BPA_C PF18040.1 KII86456.1 - 6.6 6.7 5.4 33 4.5 0.1 2.8 1 1 2 3 3 3 0 beta porphyranase A C-terminal Ribosomal_S17_N PF16205.5 KII86457.1 - 2.5e-31 107.9 1.0 4.4e-31 107.1 1.0 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KII86457.1 - 1.1e-27 95.9 0.8 4.7e-27 93.9 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 Metallophos PF00149.28 KII86458.1 - 4.8e-38 131.7 0.0 2e-37 129.7 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KII86458.1 - 2.1e-17 63.3 0.1 3.8e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EamA PF00892.20 KII86460.1 - 2.9 8.1 42.2 2.4 8.3 15.3 3.8 3 1 1 4 4 4 0 EamA-like transporter family DHFR_1 PF00186.19 KII86462.1 - 0.0068 16.1 0.0 0.028 14.1 0.0 1.9 1 1 1 2 2 2 1 Dihydrofolate reductase Ribosomal_L36 PF00444.18 KII86463.1 - 5e-19 68.2 11.0 5.8e-19 68.0 11.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Arc_trans_TRASH PF08394.10 KII86463.1 - 0.031 14.6 1.9 0.042 14.2 1.9 1.2 1 0 0 1 1 1 0 Archaeal TRASH domain N-glycanase_N PF09112.10 KII86463.1 - 0.064 13.1 0.0 0.068 13.0 0.0 1.0 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal RTA1 PF04479.13 KII86464.1 - 5.1e-60 202.6 7.6 5.1e-60 202.6 7.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Abhydrolase_9_N PF15420.6 KII86464.1 - 0.22 11.5 5.4 0.52 10.3 0.1 2.6 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus FMN_dh PF01070.18 KII86466.1 - 3.6e-81 272.9 0.1 1.4e-47 162.4 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KII86466.1 - 0.0006 18.9 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KII86466.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KII86466.1 - 0.23 10.8 3.2 1.1 8.6 3.2 2.0 1 1 0 1 1 1 0 Nitronate monooxygenase Galactosyl_T PF01762.21 KII86467.1 - 6.2e-08 32.7 0.0 0.0043 16.9 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase GST_N_3 PF13417.6 KII86468.1 - 1.2e-05 25.6 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII86468.1 - 1.7e-05 24.8 0.4 5.4e-05 23.1 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KII86468.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII86468.1 - 0.00071 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII86468.1 - 0.0033 17.6 0.1 0.011 15.9 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.10 KII86468.1 - 0.035 14.3 0.9 0.17 12.2 0.3 2.1 2 0 0 2 2 2 0 YopE, N terminal GST_C_3 PF14497.6 KII86468.1 - 0.081 13.1 0.1 0.29 11.3 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LIME1 PF15332.6 KII86470.1 - 0.073 12.7 0.3 0.51 9.9 0.1 2.1 1 1 0 2 2 2 0 Lck-interacting transmembrane adapter 1 GST_N_3 PF13417.6 KII86472.1 - 0.00089 19.6 0.0 0.00096 19.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII86472.1 - 0.18 12.2 0.0 0.21 11.9 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chitin_synth_2 PF03142.15 KII86474.1 - 0.098 11.2 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase BRF1 PF07741.13 KII86476.1 - 0.45 10.9 2.9 1.1 9.7 2.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GST_C_2 PF13410.6 KII86477.1 - 1.4e-05 25.0 0.7 4.6e-05 23.4 0.7 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII86477.1 - 2.2e-05 24.8 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII86477.1 - 0.00015 22.0 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII86477.1 - 0.00087 19.6 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII86477.1 - 0.0014 18.8 0.4 0.0072 16.5 0.4 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.10 KII86477.1 - 0.013 15.7 0.4 0.16 12.2 0.3 2.2 2 0 0 2 2 2 0 YopE, N terminal GST_C_3 PF14497.6 KII86477.1 - 0.017 15.3 0.1 0.061 13.5 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Rx_N PF18052.1 KII86477.1 - 0.12 12.7 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Glyco_transf_4 PF13439.6 KII86477.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 SGS PF05002.15 KII86478.1 - 3.7e-34 116.7 3.4 5.5e-34 116.1 3.4 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KII86478.1 - 2.3e-10 41.3 0.0 4.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 CS domain UPF0052 PF01933.18 KII86481.1 - 4.2e-47 160.8 0.0 7.4e-47 160.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Chorismate_synt PF01264.21 KII86482.1 - 3.3e-139 463.2 0.0 3.8e-139 463.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SAP30_Sin3_bdg PF13867.6 KII86483.1 - 0.0033 17.7 0.1 0.0077 16.5 0.0 1.6 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Reprolysin_5 PF13688.6 KII86485.1 - 1.1e-42 146.4 3.6 1.1e-42 146.4 3.6 2.6 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KII86485.1 - 1.5e-42 145.7 0.9 3.5e-42 144.5 0.9 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KII86485.1 - 1.9e-39 135.5 0.7 1.9e-39 135.5 0.7 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KII86485.1 - 4.8e-16 59.3 25.9 4.8e-16 59.3 25.9 4.7 3 2 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 KII86485.1 - 6.3e-13 49.3 0.3 1.9e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KII86485.1 - 4.5e-07 30.2 0.0 8.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 KII86485.1 - 3.9e-06 26.9 4.2 3.1e-05 24.0 4.2 2.4 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 KII86485.1 - 3.3e-05 24.3 14.5 3.3e-05 24.3 14.5 4.1 1 1 1 2 2 2 1 ADAM cysteine-rich domain DUF5525 PF17663.1 KII86486.1 - 0.33 9.0 7.5 0.39 8.7 7.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 KII86486.1 - 9.8 5.1 12.3 13 4.7 12.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.16 KII86487.1 - 6.1e-26 91.2 44.8 6.7e-26 91.0 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SUIM_assoc PF16619.5 KII86487.1 - 0.14 12.2 2.5 0.27 11.3 2.5 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CDC48_2 PF02933.17 KII86488.1 - 0.29 10.9 4.2 22 4.9 4.1 3.1 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Imm35 PF15567.6 KII86488.1 - 2 8.7 6.4 34 4.7 0.2 3.4 1 1 2 3 3 3 0 Immunity protein 35 FAS_N PF17828.1 KII86490.1 - 0.12 12.4 0.1 0.38 10.8 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta XPA_C PF05181.12 KII86493.1 - 0.0039 17.1 0.1 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 XPA protein C-terminus XPA_C PF05181.12 KII86494.1 - 0.028 14.4 0.2 0.12 12.4 0.2 2.0 1 1 0 1 1 1 0 XPA protein C-terminus FAM177 PF14774.6 KII86495.1 - 0.13 12.6 0.2 0.27 11.6 0.2 1.4 1 1 0 1 1 1 0 FAM177 family ABC_tran PF00005.27 KII86496.1 - 6.5e-47 159.5 0.0 5.8e-23 81.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KII86496.1 - 6.8e-22 77.3 5.7 6.8e-22 77.3 5.7 2.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KII86496.1 - 6.9e-17 62.2 16.5 0.00029 20.7 0.4 4.8 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII86496.1 - 4.2e-09 36.2 0.1 0.0069 15.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KII86496.1 - 9.2e-08 31.7 0.1 0.0058 16.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII86496.1 - 1.1e-07 31.9 0.0 0.0048 17.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII86496.1 - 6.2e-07 29.5 0.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KII86496.1 - 2.3e-06 28.2 1.6 0.4 11.2 0.0 4.6 5 0 0 5 5 4 2 AAA domain AAA_28 PF13521.6 KII86496.1 - 7.5e-06 26.3 0.2 0.089 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KII86496.1 - 9.2e-06 25.7 0.2 0.19 11.6 0.0 2.8 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.6 KII86496.1 - 0.00013 22.2 1.2 0.87 9.9 0.0 3.3 3 2 0 3 3 2 2 AAA domain MeaB PF03308.16 KII86496.1 - 0.00043 19.4 0.1 0.66 8.9 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KII86496.1 - 0.00045 20.6 3.1 0.66 10.3 0.6 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 KII86496.1 - 0.00073 20.1 14.6 0.014 15.9 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_15 PF13175.6 KII86496.1 - 0.00073 19.4 6.9 0.056 13.1 0.5 3.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 KII86496.1 - 0.0011 19.1 0.0 2.8 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KII86496.1 - 0.0012 18.6 0.0 2 8.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KII86496.1 - 0.0015 18.3 0.1 0.55 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KII86496.1 - 0.0038 17.6 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KII86496.1 - 0.0063 16.6 0.1 0.57 10.2 0.1 3.1 2 1 0 2 2 2 1 Dynamin family AAA PF00004.29 KII86496.1 - 0.0065 16.9 0.0 7.2 7.0 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KII86496.1 - 0.0075 15.8 0.1 3 7.3 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region Roc PF08477.13 KII86496.1 - 0.0085 16.3 0.0 4.6 7.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KII86496.1 - 0.017 14.3 0.1 1.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KII86496.1 - 0.018 14.2 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KII86496.1 - 0.02 15.0 7.0 0.04 14.0 0.0 3.5 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_14 PF13173.6 KII86496.1 - 0.03 14.4 0.0 11 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KII86496.1 - 0.033 14.1 0.1 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KII86496.1 - 0.035 13.7 0.1 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KII86496.1 - 0.038 13.6 0.8 19 4.8 0.0 3.8 5 0 0 5 5 5 0 AAA domain Ploopntkinase3 PF18751.1 KII86496.1 - 0.063 13.2 0.1 3.4 7.5 0.0 2.9 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KII86496.1 - 0.086 12.8 0.1 4.7 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) dNK PF01712.19 KII86496.1 - 0.1 12.4 1.4 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Deoxynucleoside kinase ATP-synt_ab PF00006.25 KII86496.1 - 0.1 12.2 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KII86496.1 - 0.7 10.2 2.6 9.3 6.6 0.1 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DNA_topoisoIV PF00521.20 KII86497.1 - 2.9e-127 425.1 0.2 5e-127 424.3 0.2 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KII86497.1 - 1.2e-52 177.6 0.6 4.2e-52 175.8 0.6 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KII86497.1 - 1.3e-28 99.6 3.4 3.1e-28 98.4 3.4 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KII86497.1 - 4.6e-11 43.2 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KII86497.1 - 3.7e-09 36.7 0.0 1.2e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Toprim domain DEAD PF00270.29 KII86498.1 - 1.4e-47 161.8 0.0 4e-47 160.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII86498.1 - 8.8e-32 109.7 0.0 2e-27 95.7 0.0 3.3 2 1 1 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KII86498.1 - 0.027 13.2 0.0 0.14 10.9 0.0 1.9 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AF-4 PF05110.13 KII86498.1 - 0.82 7.7 37.0 1.2 7.2 37.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Oxysterol_BP PF01237.18 KII86499.1 - 1.2e-86 290.9 0.1 1.6e-84 283.9 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Stimulus_sens_1 PF13756.6 KII86499.1 - 0.062 13.9 0.5 0.12 13.0 0.5 1.4 1 0 0 1 1 1 0 Stimulus-sensing domain PAM2 PF07145.15 KII86500.1 - 0.0097 15.5 10.7 0.95 9.3 0.1 4.1 4 0 0 4 4 4 2 Ataxin-2 C-terminal region Surfac_D-trimer PF09006.11 KII86500.1 - 0.13 12.2 0.3 0.45 10.5 0.3 2.0 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation TSC22 PF01166.18 KII86500.1 - 0.24 11.7 1.3 12 6.3 0.1 3.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4988 PF16378.5 KII86500.1 - 0.42 10.3 1.5 2.1 8.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function DOT1 PF08123.13 KII86502.1 - 2e-64 216.9 0.0 2.7e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KII86502.1 - 0.021 15.5 0.0 0.044 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.23 KII86503.1 - 3.9e-10 39.6 0.2 5.1e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DIOX_N PF14226.6 KII86504.1 - 3.7e-28 98.7 0.0 5.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII86504.1 - 1.1e-17 64.3 0.0 1.8e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Insulin_TMD PF17870.1 KII86505.1 - 0.64 10.1 8.1 6.5 6.9 2.5 2.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TMEM70 PF06979.12 KII86505.1 - 2.7 8.4 10.3 2 8.9 1.1 2.6 3 0 0 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex Nic96 PF04097.14 KII86506.1 - 1.9e-155 518.9 0.0 2.4e-155 518.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ST7 PF04184.12 KII86506.1 - 0.019 13.4 0.4 0.034 12.6 0.4 1.2 1 0 0 1 1 1 0 ST7 protein Spectrin PF00435.21 KII86506.1 - 0.039 14.4 0.1 0.77 10.3 0.0 3.1 3 1 1 4 4 4 0 Spectrin repeat SesA PF17107.5 KII86506.1 - 0.087 13.0 1.1 0.34 11.1 0.2 2.3 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases T2SSF PF00482.23 KII86506.1 - 0.22 11.5 1.1 0.7 9.8 0.1 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F ABC_tran PF00005.27 KII86507.1 - 1e-27 97.3 0.0 8.6e-27 94.3 0.0 2.6 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KII86507.1 - 2.2e-09 37.5 0.0 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII86507.1 - 3e-06 26.8 0.0 0.053 12.9 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KII86507.1 - 6.4e-05 22.8 0.0 0.00089 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KII86507.1 - 0.0034 17.1 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KII86507.1 - 0.011 16.3 0.1 0.021 15.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KII86507.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KII86507.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KII86507.1 - 0.018 15.3 0.0 0.075 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 KII86507.1 - 0.041 13.5 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region SbcCD_C PF13558.6 KII86507.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KII86507.1 - 0.046 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KII86507.1 - 0.048 14.1 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain LcrG PF07216.12 KII86507.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 LcrG protein UvrD-helicase PF00580.21 KII86508.1 - 1.5e-08 34.6 0.4 8e-07 28.9 0.4 2.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KII86508.1 - 5.5e-08 32.6 0.0 4.2e-06 26.4 0.0 3.0 3 1 0 4 4 4 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KII86508.1 - 8.5e-07 29.4 0.0 1e-05 25.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KII86508.1 - 7.2e-05 22.5 0.0 0.03 14.2 0.0 2.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KII86508.1 - 0.00059 20.1 1.2 0.017 15.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 KII86508.1 - 0.0022 17.6 0.0 0.023 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain DEAD PF00270.29 KII86508.1 - 0.0024 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KII86508.1 - 0.019 14.7 0.0 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 KII86508.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KII86508.1 - 0.088 13.2 1.4 0.33 11.3 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain TPR_2 PF07719.17 KII86508.1 - 0.92 9.8 11.3 0.21 11.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 KII86508.1 - 1.4 8.3 11.9 0.38 10.1 7.8 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Helicase_C PF00271.31 KII86510.1 - 2.6e-16 60.0 0.0 6.2e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII86510.1 - 3.5e-13 49.7 0.0 8.5e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KII86510.1 - 1.6e-05 25.0 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KII86510.1 - 0.051 12.4 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Ras PF00071.22 KII86511.1 - 4.2e-64 215.0 0.0 4.9e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII86511.1 - 6.9e-34 116.6 0.1 1.1e-33 116.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII86511.1 - 2.5e-14 53.1 0.1 3.2e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII86511.1 - 1.8e-05 24.4 0.1 4e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KII86511.1 - 6.3e-05 22.4 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII86511.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII86511.1 - 0.00014 21.8 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KII86511.1 - 0.016 14.8 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KII86511.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KII86511.1 - 0.037 13.8 0.0 0.15 11.8 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 KII86511.1 - 0.045 13.2 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KII86511.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KII86511.1 - 0.078 13.4 0.0 0.69 10.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 KII86511.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin MCM PF00493.23 KII86511.1 - 0.13 11.3 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 KII86511.1 - 0.14 12.4 0.0 0.62 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain Actin PF00022.19 KII86512.1 - 6.3e-48 163.4 0.0 5.5e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Actin RNA_pol_Rpc4 PF05132.14 KII86512.1 - 5 7.5 10.7 3 8.3 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 ADH_zinc_N PF00107.26 KII86514.1 - 2e-24 86.0 3.2 3.2e-24 85.4 2.7 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII86514.1 - 5.7e-19 69.5 0.8 1.1e-18 68.6 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII86514.1 - 2.1e-10 40.5 0.0 6.7e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KII86514.1 - 0.012 15.4 0.8 0.022 14.5 0.4 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Histone PF00125.24 KII86515.1 - 2.9e-22 79.4 1.9 4.3e-22 78.9 1.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KII86515.1 - 0.00012 22.3 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KII86515.1 - 0.006 17.1 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A ABM PF03992.16 KII86515.1 - 0.04 14.0 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF1018 PF06252.12 KII86515.1 - 0.12 13.3 0.8 0.32 12.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.24 KII86516.1 - 3e-17 63.2 0.0 3.7e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KII86516.1 - 5.9e-17 61.1 0.9 1.2e-16 60.1 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KII86516.1 - 1.9e-06 28.1 0.0 2.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ABM PF03992.16 KII86517.1 - 3.7e-08 33.4 0.0 7.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4937 PF16291.5 KII86517.1 - 0.12 12.7 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 PBP PF01161.20 KII86518.1 - 6.2e-16 58.9 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein COG7 PF10191.9 KII86518.1 - 0.097 10.9 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Thiolase_N PF00108.23 KII86519.1 - 1.6e-12 47.3 0.3 4.5e-11 42.6 0.3 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KII86519.1 - 9.9e-06 25.2 0.0 0.00014 21.5 0.0 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KII86519.1 - 0.026 14.1 3.4 1.2 8.7 0.4 2.7 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KII86519.1 - 0.041 13.7 2.1 0.61 10.0 0.2 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PHD PF00628.29 KII86520.1 - 1.4e-11 44.1 7.0 2.3e-11 43.4 7.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KII86520.1 - 6e-05 22.5 1.8 0.00011 21.7 1.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KII86520.1 - 0.0076 15.9 1.5 0.016 14.8 1.5 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-CW PF07496.15 KII86520.1 - 0.039 14.0 1.5 0.088 12.9 1.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Prok-RING_1 PF14446.6 KII86520.1 - 0.26 11.2 4.1 0.58 10.1 4.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE PF01363.21 KII86522.1 - 8.6e-19 67.5 7.6 8.6e-19 67.5 7.6 1.7 2 0 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 KII86522.1 - 0.64 9.9 8.1 0.82 9.6 3.6 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sel1 PF08238.12 KII86524.1 - 1.9e-17 63.3 6.5 1.2e-05 25.8 0.1 3.2 3 0 0 3 3 3 3 Sel1 repeat Enolase_like_N PF18374.1 KII86524.1 - 0.14 11.5 0.8 3.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Enolase N-terminal domain-like A1_Propeptide PF07966.12 KII86528.1 - 1.4 8.9 0.1 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 A1 Propeptide Cauli_VI PF01693.16 KII86529.1 - 8.9e-07 29.1 4.3 1e-06 28.9 0.3 2.7 3 0 0 3 3 3 1 Caulimovirus viroplasmin MRP-L46 PF11788.8 KII86530.1 - 1.8 9.4 4.6 0.27 12.0 0.3 1.8 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 CxC1 PF18802.1 KII86536.1 - 1.2e-05 25.4 0.1 1.5e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII86536.1 - 0.00022 21.3 0.1 0.00026 21.1 0.1 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII86537.1 - 5.4e-15 55.6 0.3 7.9e-15 55.1 0.3 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FTCD_C PF04961.12 KII86537.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase KDZ PF18758.1 KII86538.1 - 2.4e-36 125.5 0.0 2.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase His_Phos_1 PF00300.22 KII86540.1 - 1.1 8.9 6.4 0.45 10.2 0.4 3.1 3 1 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) KDZ PF18758.1 KII86544.1 - 4.4e-62 209.6 0.0 7.8e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII86544.1 - 3.2e-08 33.6 0.1 7.5e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII86544.1 - 0.00019 21.6 0.2 0.00078 19.6 0.1 2.1 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases SKA2 PF16740.5 KII86544.1 - 0.039 13.7 3.0 0.093 12.5 2.0 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Pkinase_fungal PF17667.1 KII86545.1 - 2.2e-46 158.4 0.0 5.2e-46 157.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII86545.1 - 4.7e-06 26.2 0.3 0.00023 20.6 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain DUF599 PF04654.12 KII86545.1 - 0.021 14.2 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Pkinase_Tyr PF07714.17 KII86545.1 - 0.2 10.9 0.8 0.34 10.1 0.0 1.7 3 0 0 3 3 3 0 Protein tyrosine kinase Exo_endo_phos PF03372.23 KII86547.1 - 3.8e-05 23.3 0.0 7.4e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KII86547.1 - 5.1e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KII86549.1 - 4.2e-06 26.4 0.0 6.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SH3_3 PF08239.11 KII86549.1 - 0.11 12.7 0.1 8.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain F-box-like PF12937.7 KII86550.1 - 0.0081 16.0 1.4 0.032 14.1 1.2 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII86551.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.5 2 1 1 3 3 3 0 F-box-like F-box-like PF12937.7 KII86553.1 - 0.021 14.7 0.4 0.021 14.7 0.4 2.5 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 KII86553.1 - 0.094 12.6 0.9 0.4 10.6 0.1 2.3 2 0 0 2 2 2 0 F-box domain Thaumatin PF00314.17 KII86556.1 - 0.00027 20.6 6.6 0.023 14.3 6.9 2.5 1 1 0 1 1 1 1 Thaumatin family Thaumatin PF00314.17 KII86557.1 - 1.7e-05 24.6 12.4 0.00031 20.5 5.9 3.4 1 1 0 2 2 2 1 Thaumatin family SR-25 PF10500.9 KII86557.1 - 1.3 8.5 13.2 2.2 7.8 13.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NUDE_C PF04880.13 KII86557.1 - 6.8 7.1 9.5 11 6.5 9.5 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region F-box-like PF12937.7 KII86559.1 - 0.078 12.9 0.5 0.54 10.2 0.0 2.4 2 0 0 2 2 2 0 F-box-like PQ-loop PF04193.14 KII86560.1 - 8.2e-22 76.7 8.3 1.4e-10 40.8 0.3 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KII86560.1 - 0.1 13.4 4.0 0.2 12.5 4.0 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor eIF3_N PF09440.10 KII86561.1 - 4.9e-47 159.7 2.2 4.9e-47 159.7 2.2 2.7 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KII86561.1 - 8e-09 36.0 0.1 3e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 PCI domain Aminotran_1_2 PF00155.21 KII86562.1 - 1.9e-38 132.6 0.0 2.2e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII86562.1 - 0.00014 20.5 0.0 0.00021 20.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KII86562.1 - 0.00029 20.3 1.2 0.00046 19.6 1.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KII86562.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 KII86562.1 - 0.034 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase WW PF00397.26 KII86563.1 - 2e-05 24.6 0.7 3.8e-05 23.7 0.7 1.5 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 KII86563.1 - 0.14 12.1 13.9 0.17 11.9 13.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KII86563.1 - 0.28 11.8 15.8 0.44 11.2 15.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM70 PF14967.6 KII86563.1 - 1.5 8.2 8.8 2.1 7.7 8.8 1.1 1 0 0 1 1 1 0 FAM70 protein Methyltransf_32 PF13679.6 KII86565.1 - 5.7e-28 97.9 0.0 8.5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII86565.1 - 0.00018 22.2 0.0 0.00042 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII86565.1 - 0.0055 17.3 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII86565.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KII86565.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KII86565.1 - 0.036 14.8 0.0 0.076 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.14 KII86565.1 - 0.046 13.2 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase TRM13 MetW PF07021.12 KII86565.1 - 0.061 12.9 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KII86565.1 - 0.17 11.7 0.1 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 KII86568.1 - 1.1e-59 202.5 0.0 2.4e-59 201.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Homeobox_KN PF05920.11 KII86569.1 - 7.3e-18 64.2 0.0 7.3e-18 64.2 0.0 2.3 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 KII86569.1 - 0.00018 21.2 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain LRR_4 PF12799.7 KII86570.1 - 3.1e-31 106.9 26.6 3.4e-05 24.1 0.1 8.5 6 1 1 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII86570.1 - 7.6e-25 86.5 36.5 7e-07 28.9 4.0 6.3 5 1 1 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KII86570.1 - 1.5e-13 50.6 12.1 0.00076 19.0 0.1 5.1 3 1 3 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 KII86570.1 - 0.25 12.0 32.3 6.1 7.8 0.3 10.0 7 4 1 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 KII86570.1 - 6.6 7.1 20.2 27 5.2 1.1 7.9 9 0 0 9 9 9 0 Leucine Rich repeat Pkinase PF00069.25 KII86576.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Kinase-like PF14531.6 KII86576.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Oxidored_FMN PF00724.20 KII86578.1 - 5.4e-43 147.6 0.0 6.8e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_3 PF07859.13 KII86579.1 - 9.3e-15 55.0 0.3 7.6e-14 52.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII86579.1 - 1.7e-08 33.9 0.0 6.3e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KII86579.1 - 2.6e-05 23.3 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme F-box-like PF12937.7 KII86581.1 - 0.00019 21.3 0.2 0.00043 20.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86581.1 - 0.00039 20.2 0.2 0.00073 19.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII86582.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like Iwr1 PF08574.10 KII86583.1 - 2.5e-12 47.6 6.1 2.5e-12 47.6 6.1 3.1 3 0 0 3 3 3 1 Transcription factor Iwr1 Caleosin PF05042.13 KII86584.1 - 3.7e-58 196.2 0.0 4.1e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Caleosin related protein Glyco_hydro_16 PF00722.21 KII86586.1 - 1.1e-06 28.2 0.0 7.7e-06 25.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 7tm_7 PF08395.12 KII86587.1 - 0.019 14.2 1.2 0.019 14.2 1.2 1.8 1 1 0 1 1 1 0 7tm Chemosensory receptor F-box-like PF12937.7 KII86589.1 - 0.0013 18.6 0.1 0.0033 17.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Mif2_N PF15624.6 KII86590.1 - 0.013 16.2 4.7 0.02 15.6 4.7 1.3 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Totivirus_coat PF05518.11 KII86590.1 - 3.9 5.4 6.4 3.8 5.4 6.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein ICMT PF04140.14 KII86592.1 - 8.3e-13 48.6 0.1 1.2e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII86592.1 - 5e-11 42.9 1.0 8.6e-09 35.7 0.1 2.9 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII86592.1 - 8.3e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family UPF0126 PF03458.13 KII86592.1 - 0.0032 17.3 0.1 0.0079 16.1 0.1 1.6 1 0 0 1 1 1 1 UPF0126 domain ICMT PF04140.14 KII86593.1 - 1.6e-13 50.9 0.2 4.8e-12 46.1 0.0 2.6 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII86593.1 - 6.8e-10 39.3 0.5 1.6e-08 34.9 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII86593.1 - 3e-06 26.3 0.0 4.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Pkinase PF00069.25 KII86594.1 - 5e-15 55.6 0.0 6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86594.1 - 4.2e-08 32.8 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII86594.1 - 4.7e-06 26.7 0.7 8.6e-06 25.8 0.6 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII86594.1 - 5.8e-05 22.5 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII86594.1 - 0.00041 20.0 0.1 0.00057 19.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KII86594.1 - 0.0026 17.1 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sulfatase PF00884.23 KII86595.1 - 8.4e-50 169.9 0.0 1.1e-49 169.5 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KII86595.1 - 0.029 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KII86595.1 - 0.076 13.3 0.9 0.16 12.3 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 KII86595.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) F-box-like PF12937.7 KII86597.1 - 2.8e-05 23.9 0.7 0.00013 21.7 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII86597.1 - 0.027 14.4 0.4 0.23 11.4 0.0 2.8 3 0 0 3 3 3 0 F-box domain HVSL PF09749.9 KII86598.1 - 4.5e-44 150.7 0.1 1.8e-43 148.7 0.1 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KII86598.1 - 5.4e-08 32.9 2.2 6.6e-08 32.6 0.9 1.6 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily MFS_1 PF07690.16 KII86599.1 - 3.2e-43 148.0 18.0 7.8e-43 146.7 18.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII86599.1 - 1.9e-10 40.2 18.4 6.1e-10 38.5 2.5 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 KII86599.1 - 9e-06 24.5 1.5 9e-06 24.5 1.5 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 KII86599.1 - 6.6e-05 21.5 8.2 0.00051 18.6 3.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 KII86599.1 - 0.00027 19.9 7.6 0.009 14.9 0.1 3.2 3 0 0 3 3 3 3 MFS_1 like family OATP PF03137.20 KII86599.1 - 0.015 13.6 0.4 0.035 12.4 0.3 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GST_C_6 PF17171.4 KII86599.1 - 0.021 14.6 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain cobW PF02492.19 KII86600.1 - 3.8e-32 111.3 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KII86600.1 - 0.0015 17.6 0.1 0.066 12.2 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KII86600.1 - 0.0041 17.2 0.0 0.0088 16.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KII86600.1 - 0.019 15.5 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KII86600.1 - 0.042 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 KII86600.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KII86600.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 KII86600.1 - 0.066 12.7 0.1 4.2 6.9 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KII86600.1 - 0.095 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KII86600.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SelP_N PF04592.14 KII86600.1 - 6.4 6.1 9.2 9.3 5.6 9.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Acetyltransf_7 PF13508.7 KII86601.1 - 0.0009 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KII86602.1 - 7.2e-36 123.8 40.5 7.2e-36 123.8 40.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII86602.1 - 1.1e-05 24.1 1.7 2.1e-05 23.2 1.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KII86603.1 - 0.00067 19.5 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86603.1 - 0.013 15.3 0.7 0.24 11.3 0.0 2.9 3 0 0 3 3 3 0 F-box domain PRRSV_Env PF02340.15 KII86603.1 - 0.023 14.1 0.2 0.097 12.0 0.1 1.9 2 0 0 2 2 2 0 PRRSV putative envelope protein LRR_4 PF12799.7 KII86603.1 - 0.31 11.5 4.9 3.2 8.3 0.8 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 KII86605.1 - 2.6e-46 157.6 0.0 3.4e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86605.1 - 2.3e-35 122.2 0.0 2.8e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86605.1 - 1.3e-08 35.0 0.2 4.1e-08 33.3 0.1 1.8 3 0 0 3 3 3 1 KR domain DUF1776 PF08643.10 KII86605.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KII86605.1 - 0.0006 19.3 0.1 0.0014 18.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HEM4 PF02602.15 KII86605.1 - 0.013 14.9 0.1 0.025 13.9 0.1 1.4 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Eno-Rase_NADH_b PF12242.8 KII86605.1 - 0.025 14.3 0.5 0.046 13.5 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KII86605.1 - 0.039 13.4 0.0 0.074 12.4 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KII86605.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NDC10_II PF16787.5 KII86607.1 - 7.5e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF4637 PF15470.6 KII86608.1 - 0.042 13.6 0.2 0.044 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1180 PF06679.12 KII86610.1 - 0.018 15.5 2.9 0.018 15.5 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) RAP1 PF07218.11 KII86610.1 - 6.4 4.9 4.6 8.9 4.5 4.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTB PF00651.31 KII86612.1 - 0.017 15.4 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain GST_N_3 PF13417.6 KII86613.1 - 5e-11 42.8 0.1 8.5e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII86613.1 - 1.3e-10 41.4 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII86613.1 - 7.4e-09 35.5 0.3 1.4e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KII86613.1 - 2.6e-06 27.7 0.1 5.4e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KII86613.1 - 0.0051 17.4 0.0 0.013 16.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII86613.1 - 0.035 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KII86613.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin adh_short PF00106.25 KII86615.1 - 1.2e-23 83.6 0.3 1.5e-23 83.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86615.1 - 5.4e-19 68.7 1.2 6.7e-19 68.4 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86615.1 - 5.2e-05 23.2 0.2 6.6e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII86615.1 - 0.0048 16.8 1.4 0.008 16.1 1.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII86615.1 - 0.084 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ferric_reduct PF01794.19 KII86617.1 - 1.3e-17 64.1 10.9 2.5e-17 63.1 10.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KII86617.1 - 1.3e-16 61.1 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII86617.1 - 3.1e-06 27.2 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ribosomal_L34 PF00468.17 KII86618.1 - 1.1e-19 70.2 10.8 1.6e-19 69.6 10.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 TAF1D PF15333.6 KII86618.1 - 0.073 12.8 0.9 0.078 12.7 0.9 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Peptidase_C97 PF05903.14 KII86619.1 - 3.5e-40 137.3 0.0 5e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 KII86619.1 - 2.2e-38 132.1 1.1 3.8e-38 131.3 0.1 1.7 2 0 0 2 2 2 1 PUL domain Thioredoxin PF00085.20 KII86619.1 - 1.9e-10 40.6 0.0 4.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KII86619.1 - 0.0001 22.7 0.0 0.0012 19.3 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HEAT_2 PF13646.6 KII86619.1 - 0.074 13.5 2.1 3.3 8.2 0.2 3.3 3 0 0 3 3 3 0 HEAT repeats CLASP_N PF12348.8 KII86620.1 - 7.9e-23 81.2 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KII86620.1 - 0.23 11.8 0.9 3.2 8.3 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat SET PF00856.28 KII86621.1 - 2.2e-10 41.2 0.0 1.9e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KII86621.1 - 0.16 12.6 0.3 10 6.9 0.1 2.3 2 0 0 2 2 2 0 SAF domain SET PF00856.28 KII86622.1 - 2.9e-10 40.8 0.0 1.5e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KII86622.1 - 0.00077 20.0 0.2 0.2 12.3 0.1 2.6 2 0 0 2 2 2 2 SAF domain TPR_8 PF13181.6 KII86622.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 KII86623.1 - 4.3e-05 23.3 0.3 4.3e-05 23.3 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII86623.1 - 0.0012 18.7 4.6 0.0014 18.5 0.1 2.9 3 0 0 3 3 3 1 F-box domain CMAS PF02353.20 KII86625.1 - 1.4e-53 181.9 0.0 9.9e-41 139.8 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII86625.1 - 1.1e-09 38.8 0.0 3.3e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII86625.1 - 4e-06 27.4 0.0 1.4e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KII86625.1 - 1.2e-05 24.9 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KII86625.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86625.1 - 0.00024 21.8 0.0 0.00054 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII86625.1 - 0.00044 20.1 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KII86625.1 - 0.0022 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KII86625.1 - 0.015 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KII86625.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GCD14 PF08704.10 KII86625.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit HetR_C PF18460.1 KII86625.1 - 0.29 11.1 1.2 0.62 10.0 0.1 2.1 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain RRM_1 PF00076.22 KII86626.1 - 5.9e-09 35.6 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KII86626.1 - 9e-05 22.5 0.1 0.00022 21.2 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KII86626.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KII86626.1 - 0.05 13.5 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif SET PF00856.28 KII86627.1 - 7.9e-12 45.9 0.6 2.4e-10 41.1 0.3 2.7 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KII86627.1 - 0.019 15.6 0.1 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 SAF domain DUF2808 PF10989.8 KII86627.1 - 0.21 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) SET PF00856.28 KII86628.1 - 1.3e-13 51.7 0.2 1.1e-11 45.4 0.2 3.0 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KII86628.1 - 0.004 17.8 0.1 0.84 10.3 0.0 2.4 2 0 0 2 2 2 2 SAF domain TPR_19 PF14559.6 KII86628.1 - 0.15 12.6 0.6 0.58 10.7 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 KII86629.1 - 2e-16 60.1 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII86629.1 - 9.5e-15 55.1 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII86629.1 - 1.6e-13 51.1 0.1 3.9e-13 49.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII86629.1 - 1.3e-12 47.9 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86629.1 - 1.9e-12 47.8 0.0 3.3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII86629.1 - 4.5e-10 39.3 0.0 9.5e-10 38.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KII86629.1 - 1.8e-09 37.7 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KII86629.1 - 1.4e-07 31.2 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KII86629.1 - 3.8e-05 22.8 0.0 5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KII86629.1 - 0.00013 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 KII86629.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 KII86629.1 - 0.005 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KII86629.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 KII86629.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DREV PF05219.12 KII86629.1 - 0.033 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 KII86629.1 - 0.036 14.1 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KII86629.1 - 0.059 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.18 KII86629.1 - 0.081 12.6 0.2 0.69 9.6 0.2 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 KII86629.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 KII86629.1 - 0.27 10.3 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Vma12 PF11712.8 KII86630.1 - 1.2 9.1 4.0 1.6 8.8 0.8 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3087 PF11286.8 KII86630.1 - 3.4 7.1 5.2 0.58 9.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Abhydrolase_6 PF12697.7 KII86631.1 - 1.1e-13 52.3 2.2 1.1e-13 52.3 2.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII86631.1 - 4.3e-13 49.1 0.1 3.7e-09 36.2 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII86631.1 - 3e-12 46.8 0.2 5.4e-09 36.1 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KII86631.1 - 3.5e-08 33.6 0.3 7.4e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII86631.1 - 2.2e-05 24.0 0.0 0.00013 21.5 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KII86631.1 - 0.0048 16.5 0.0 0.46 10.0 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Thioesterase PF00975.20 KII86631.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S15 PF02129.18 KII86631.1 - 0.011 15.3 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 KII86631.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 KII86631.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KII86631.1 - 0.032 13.8 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KII86631.1 - 0.049 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.8 KII86631.1 - 0.049 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF818 PF05677.12 KII86631.1 - 0.05 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Chlorophyllase2 PF12740.7 KII86631.1 - 0.12 11.2 0.0 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 KII86631.1 - 0.16 11.8 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase HCO3_cotransp PF00955.21 KII86632.1 - 1.8e-77 261.4 6.6 3e-35 122.0 3.3 3.0 2 1 1 3 3 3 3 HCO3- transporter family His_Phos_2 PF00328.22 KII86633.1 - 0.001 18.5 0.1 0.017 14.5 0.0 2.5 2 1 1 3 3 3 1 Histidine phosphatase superfamily (branch 2) Ost4 PF10215.9 KII86633.1 - 0.26 11.2 4.8 31 4.5 4.8 2.6 2 0 0 2 2 2 0 Oligosaccaryltransferase F-box-like PF12937.7 KII86634.1 - 7.6e-11 41.7 0.6 2.5e-10 40.1 0.6 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII86634.1 - 0.14 12.6 0.0 8.9 6.9 0.0 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Herpes_IE68 PF02479.16 KII86635.1 - 0.049 13.2 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus immediate early protein AMP-binding PF00501.28 KII86637.1 - 3.9e-88 295.9 0.0 5.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII86637.1 - 2.7e-17 63.5 0.2 1.9e-16 60.8 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SET PF00856.28 KII86638.1 - 8.3e-08 32.8 0.0 1.2e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 SET domain Amidohydro_2 PF04909.14 KII86639.1 - 1.3e-19 71.1 0.0 2.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KII86639.1 - 5.4e-05 22.7 0.0 0.00024 20.6 0.0 2.2 1 1 0 1 1 1 1 TatD related DNase BTB PF00651.31 KII86641.1 - 0.0078 16.4 0.1 0.025 14.8 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain SatRNA_48 PF17485.2 KII86641.1 - 0.013 14.6 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein Mito_carr PF00153.27 KII86642.1 - 8.4e-77 253.2 0.1 6.7e-28 96.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tyrosinase PF00264.20 KII86644.1 - 4.1e-30 105.7 5.1 5.5e-30 105.3 5.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 KII86645.1 - 7.7e-32 111.4 4.3 1e-31 111.0 4.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase GPI-anchored PF10342.9 KII86646.1 - 1.6e-08 35.2 0.1 2.3e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII86646.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KII86647.1 - 1.8e-06 28.6 0.0 2.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.7 KII86648.1 - 0.02 14.8 0.5 0.052 13.5 0.5 1.7 1 0 0 1 1 1 0 F-box-like EBP PF05241.12 KII86649.1 - 1.4e-66 223.4 7.1 1.6e-66 223.2 7.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein Glyco_hydro_16 PF00722.21 KII86650.1 - 0.0017 17.8 0.0 0.0092 15.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GPI-anchored PF10342.9 KII86651.1 - 3.6e-07 30.9 0.0 4.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KII86653.1 - 1.3e-07 32.3 0.0 2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3857 PF12969.7 KII86653.1 - 0.071 13.2 0.0 0.16 12.0 0.0 1.5 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) Amidohydro_2 PF04909.14 KII86655.1 - 2.4e-33 116.2 0.2 3e-33 115.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase TrkA_N PF02254.18 KII86655.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GPI-anchored PF10342.9 KII86656.1 - 4.4e-05 24.2 0.0 4.4e-05 24.2 0.0 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII86656.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1905 PF08922.11 KII86656.1 - 0.08 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) SOG2 PF10428.9 KII86656.1 - 0.3 10.2 13.1 0.34 10.0 13.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein CHRD PF07452.12 KII86656.1 - 0.47 11.4 6.0 2.1 9.3 6.0 2.2 1 1 0 1 1 1 0 CHRD domain SPX PF03105.19 KII86656.1 - 4.3 7.1 6.5 4.9 7.0 6.5 1.1 1 0 0 1 1 1 0 SPX domain DPBB_1 PF03330.18 KII86657.1 - 0.00079 19.7 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase DUF35_N PF12172.8 KII86657.1 - 0.14 12.1 0.4 0.31 10.9 0.4 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_9 PF14369.6 KII86657.1 - 0.26 11.6 1.4 1.2 9.5 0.9 2.2 2 1 0 2 2 2 0 zinc-ribbon Ubiq_cyt_C_chap PF03981.12 KII86659.1 - 8.3e-24 84.3 0.0 1.8e-12 47.5 0.0 2.9 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone CAP_N PF01213.19 KII86659.1 - 3.3 7.1 5.0 1.1 8.7 1.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SH3_9 PF14604.6 KII86660.1 - 5e-23 80.7 0.5 3.6e-13 49.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KII86660.1 - 7e-19 67.2 0.5 4.5e-08 32.6 0.0 2.7 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KII86660.1 - 1.9e-18 65.9 0.1 1.2e-09 37.7 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 KII86660.1 - 3.1e-15 56.2 1.3 1.5e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KII86660.1 - 1e-12 47.7 4.7 1.7e-12 47.0 4.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KII86660.1 - 0.00037 20.7 0.3 0.00037 20.7 0.3 2.4 3 0 0 3 3 3 1 Bacterial SH3 domain CAF1 PF04857.20 KII86661.1 - 2.7e-21 76.1 0.4 3.2e-12 46.3 0.0 2.8 1 1 1 2 2 2 2 CAF1 family ribonuclease Fungal_trans PF04082.18 KII86662.1 - 3.1e-17 62.5 1.3 7.3e-17 61.3 1.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII86662.1 - 0.00014 21.9 10.8 0.00026 21.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3446 PF11928.8 KII86662.1 - 1.8 8.9 10.1 4.9 7.5 2.3 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Fungal_trans PF04082.18 KII86663.1 - 8.6e-13 47.9 0.2 8.6e-13 47.9 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII86663.1 - 0.00073 19.6 13.4 0.0013 18.8 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.20 KII86664.1 - 1.5e-189 631.5 0.0 1.7e-189 631.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KII86665.1 - 8.7e-41 140.0 45.4 4.9e-39 134.2 47.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII86665.1 - 9.2e-12 44.2 15.8 1.5e-11 43.5 15.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KII86665.1 - 8.6e-11 41.3 7.4 8.6e-11 41.3 7.4 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter DUF3392 PF11872.8 KII86665.1 - 2.1 8.7 6.4 1.6 9.0 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3392) Tyrosinase PF00264.20 KII86666.1 - 1.1e-23 84.7 4.0 2.3e-23 83.7 4.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Aldo_ket_red PF00248.21 KII86667.1 - 8.3e-43 146.7 0.0 5.1e-41 140.8 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.31 KII86668.1 - 0.0064 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.23 KII86669.1 - 0.056 13.4 0.0 0.58 10.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad1 PF08649.10 KII86670.1 - 3.2e-22 78.5 0.3 4.2e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KII86670.1 - 0.095 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.25 KII86671.1 - 3.4e-62 210.2 0.0 8.5e-62 208.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86671.1 - 1.2e-35 123.1 0.0 1.9e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KII86671.1 - 7.2e-20 70.6 27.9 1.6e-11 43.9 10.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KII86671.1 - 6.5e-18 64.6 31.2 1.8e-12 47.2 3.0 2.9 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 KII86671.1 - 3.9e-11 43.5 0.3 5.9e-10 39.7 0.5 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KII86671.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 KII86671.1 - 0.012 14.6 0.1 0.023 13.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KII86671.1 - 0.14 10.9 0.5 0.69 8.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase C1_2 PF03107.16 KII86671.1 - 0.32 11.4 22.3 2.1 8.7 7.7 2.6 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 KII86671.1 - 7.1 6.8 17.3 6.7 6.9 6.0 3.2 3 0 0 3 3 3 0 Up-regulated During Septation DUF3871 PF12987.7 KII86672.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) Endosulfine PF04667.17 KII86673.1 - 4.5e-28 97.2 0.1 7e-28 96.6 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Aldo_ket_red PF00248.21 KII86674.1 - 3.1e-72 243.2 0.0 3.6e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII86675.1 - 1.2e-72 244.6 0.0 1.5e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_red_lgC PF02867.15 KII86676.1 - 1.4e-178 594.7 0.0 2e-178 594.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KII86676.1 - 4.3e-24 84.3 0.1 1.3e-23 82.8 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KII86676.1 - 1.8e-17 63.7 0.0 4.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Gal11_ABD1 PF18535.1 KII86676.1 - 0.024 14.7 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) GTP_EFTU PF00009.27 KII86678.1 - 5.6e-57 192.4 0.0 8.6e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KII86678.1 - 1.1e-15 57.4 0.0 4.1e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KII86678.1 - 3.1e-08 33.6 0.0 7.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KII86678.1 - 1.3e-07 31.9 0.0 3.6e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII86678.1 - 0.0001 22.3 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KII86678.1 - 0.097 12.1 0.0 0.8 9.1 0.1 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit EFG_IV PF03764.18 KII86678.1 - 0.13 12.0 0.0 4 7.2 0.0 2.7 1 1 1 2 2 2 0 Elongation factor G, domain IV NTP_transf_9 PF04248.12 KII86679.1 - 5.7e-32 109.5 0.4 6.4e-32 109.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) 4HBT_3 PF13622.6 KII86680.1 - 1.5e-27 97.4 0.7 2.1e-27 97.0 0.7 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DHHC PF01529.20 KII86681.1 - 5.5e-31 107.4 9.0 5.5e-31 107.4 9.0 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 KII86681.1 - 0.081 12.8 7.2 0.16 11.9 7.2 1.4 1 0 0 1 1 1 0 Ribosomal L40e family QueC PF06508.13 KII86681.1 - 0.33 10.4 1.1 0.53 9.7 1.1 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Na_sulph_symp PF00939.19 KII86681.1 - 8.4 5.3 8.8 1.9 7.4 0.5 2.0 2 0 0 2 2 2 0 Sodium:sulfate symporter transmembrane region Methyltransf_33 PF10017.9 KII86682.1 - 2.2e-75 253.7 0.0 1.4e-74 251.0 0.0 1.9 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KII86682.1 - 1.1e-23 84.2 1.8 5.3e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KII86682.1 - 0.0014 19.1 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 DinB superfamily Gelsolin PF00626.22 KII86683.1 - 1.8e-37 127.1 0.1 3.3e-17 62.1 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat CodY PF06018.14 KII86683.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 CodY GAF-like domain WD40 PF00400.32 KII86684.1 - 4.6e-07 30.4 10.7 1.4 9.9 0.2 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 KII86684.1 - 0.00042 19.7 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Frtz PF11768.8 KII86684.1 - 0.27 9.5 0.0 0.81 7.9 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Aldo_ket_red PF00248.21 KII86685.1 - 2.8e-69 233.6 0.0 3.1e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII86686.1 - 1.2e-68 231.5 0.0 1.4e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2 PF00096.26 KII86687.1 - 7e-11 42.0 10.6 1.1e-05 25.6 1.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII86687.1 - 3.2e-09 36.8 15.2 1.3e-06 28.6 3.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII86687.1 - 1.1e-06 28.9 8.6 0.0064 17.2 1.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KII86687.1 - 0.012 16.3 0.8 1.1 10.0 0.1 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KII86687.1 - 0.077 13.1 0.4 0.58 10.3 0.4 1.9 1 1 0 1 1 1 0 Aberrant zinc-finger Aldo_ket_red PF00248.21 KII86688.1 - 1.9e-70 237.4 0.0 2.3e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Arrestin_N PF00339.29 KII86689.1 - 0.19 11.8 0.1 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Asp PF00026.23 KII86690.1 - 4.4e-50 170.9 18.2 1.6e-49 169.0 18.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII86690.1 - 1.1e-07 32.3 8.9 6.6e-05 23.2 0.5 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII86690.1 - 0.0009 19.8 4.5 0.057 14.1 1.1 2.8 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KII86690.1 - 0.17 12.5 3.0 0.78 10.3 0.2 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 KII86691.1 - 8.6e-41 140.4 0.5 1.2e-40 139.9 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII86691.1 - 5.8e-05 23.4 7.5 0.0041 17.4 5.6 3.1 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII86691.1 - 0.00045 20.8 1.7 0.091 13.4 0.4 2.8 2 0 0 2 2 2 2 Aspartyl protease Atrophin-1 PF03154.15 KII86691.1 - 4 5.6 4.5 0.53 8.5 0.6 1.4 2 0 0 2 2 2 0 Atrophin-1 family PAPA-1 PF04795.12 KII86692.1 - 1.2e-20 74.1 3.1 2.2e-20 73.3 3.1 1.4 1 0 0 1 1 1 1 PAPA-1-like conserved region DUF5364 PF17322.2 KII86692.1 - 0.0074 16.6 3.2 0.0074 16.6 3.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5364) HemY_N PF07219.13 KII86692.1 - 0.47 10.7 1.9 0.73 10.1 1.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DotU PF09850.9 KII86693.1 - 0.056 13.2 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system protein DotU RRM_1 PF00076.22 KII86694.1 - 6.7e-11 41.8 0.7 0.00041 20.1 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 KII86695.1 - 6.9e-46 156.8 42.7 1.4e-32 113.0 15.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII86695.1 - 1.6e-09 37.1 9.4 1.6e-09 37.1 9.4 2.9 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 KII86695.1 - 0.00033 19.2 10.8 0.00033 19.2 10.8 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KII86695.1 - 3.6 5.7 20.6 0.19 10.0 0.6 4.1 4 1 1 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_FMN PF00724.20 KII86696.1 - 9e-45 153.4 0.0 1.2e-44 153.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMO-like PF00743.19 KII86697.1 - 2.5e-23 82.3 0.0 8.8e-12 44.2 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII86697.1 - 6.4e-16 58.5 0.1 3.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII86697.1 - 2.9e-10 39.9 0.0 1.2e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII86697.1 - 2.4e-08 34.1 0.0 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KII86697.1 - 5.2e-07 29.1 0.0 2.3e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KII86697.1 - 8.1e-05 22.4 0.1 0.00038 20.2 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII86697.1 - 0.0014 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KII86697.1 - 0.0014 18.0 0.0 0.014 14.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KII86697.1 - 0.0021 17.4 0.0 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 KII86697.1 - 0.0097 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 KII86697.1 - 0.013 15.5 0.0 0.074 13.0 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KII86697.1 - 0.015 14.0 0.0 0.076 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pectinesterase PF01095.19 KII86698.1 - 2e-35 122.0 4.2 2.5e-35 121.7 4.2 1.0 1 0 0 1 1 1 1 Pectinesterase XPG_N PF00752.17 KII86699.1 - 1.7e-33 115.1 0.0 3.4e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KII86699.1 - 5.2e-29 100.4 0.2 1.2e-28 99.3 0.0 1.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KII86699.1 - 6.2e-06 26.7 0.1 1.6e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.15 KII86699.1 - 0.025 14.7 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF3881 PF12997.7 KII86699.1 - 0.094 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF4305 PF14146.6 KII86701.1 - 2.6 8.3 7.2 0.64 10.3 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) Glyco_hydro_35 PF01301.19 KII86702.1 - 2.4e-72 244.2 0.2 1.9e-45 155.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KII86702.1 - 3.5e-55 185.5 7.2 1.4e-30 106.2 0.2 3.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KII86702.1 - 3.7e-37 127.9 6.2 5.9e-37 127.2 6.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KII86702.1 - 2.5e-20 71.8 1.1 2e-19 68.9 0.1 2.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 MFS_1 PF07690.16 KII86703.1 - 1.2e-13 50.7 53.9 3.8e-10 39.2 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PsaM PF07465.13 KII86703.1 - 3.1 7.6 6.4 35 4.2 2.1 3.0 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Amino_oxidase PF01593.24 KII86705.1 - 3.6e-21 76.0 0.0 2.4e-18 66.7 0.0 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII86705.1 - 6.8e-14 51.9 0.0 1.4e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII86705.1 - 9.4e-06 25.4 0.1 0.00052 19.7 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII86705.1 - 4e-05 23.7 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KII86705.1 - 0.0031 16.8 0.0 0.059 12.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII86705.1 - 0.086 11.5 0.0 1.8 7.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KII86705.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Na_H_Exchanger PF00999.21 KII86706.1 - 1.8e-64 217.9 22.8 2.1e-64 217.7 22.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4552 PF15089.6 KII86706.1 - 0.14 11.2 0.3 0.26 10.3 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4552) TRADD_N PF09034.10 KII86706.1 - 0.2 11.7 0.1 0.37 10.9 0.1 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain 60KD_IMP PF02096.20 KII86706.1 - 1.4 8.8 4.0 1.4 8.8 0.6 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein YrhC PF14143.6 KII86706.1 - 1.7 8.8 4.0 16 5.7 0.2 2.9 2 0 0 2 2 2 0 YrhC-like protein zf-RING_5 PF14634.6 KII86708.1 - 0.00077 19.4 3.0 0.0013 18.6 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 KII86708.1 - 2.6 8.3 6.9 20 5.4 6.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 KII86708.1 - 9.6 6.1 9.7 63 3.5 9.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 KII86711.1 - 5.4e-08 32.5 0.5 1.2e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII86711.1 - 3.9e-06 26.7 0.9 6.8e-06 25.9 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KII86711.1 - 0.2 11.5 1.2 0.21 11.5 0.1 1.6 2 0 0 2 2 2 0 F-box Pex24p PF06398.11 KII86713.1 - 3.7e-28 98.6 13.9 2.2e-27 96.0 13.9 1.9 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DSPc PF00782.20 KII86714.1 - 2.3e-24 85.7 0.0 2.8e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII86714.1 - 0.031 13.8 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KII86714.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1320 PF07030.12 KII86714.1 - 0.34 11.0 1.1 12 6.0 1.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1320) F-box-like PF12937.7 KII86715.1 - 2.6e-09 36.8 0.9 5.9e-09 35.7 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86715.1 - 0.033 14.1 0.0 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 F-box domain ketoacyl-synt PF00109.26 KII86717.1 - 1.2e-81 274.0 0.0 2.8e-81 272.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KII86717.1 - 1.4e-47 162.8 0.0 2.1e-44 152.4 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KII86717.1 - 7.8e-36 122.7 0.1 1.9e-35 121.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KII86717.1 - 2.2e-29 102.9 2.9 2.2e-29 102.9 2.9 3.0 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KII86717.1 - 2.2e-26 92.8 0.1 3.7e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KII86717.1 - 1.1e-23 83.3 3.4 6e-12 45.7 0.2 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 KII86717.1 - 1.9e-19 70.7 0.2 1.7e-18 67.6 0.0 2.6 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.7 KII86717.1 - 1.7e-07 32.1 8.1 1.5e-06 29.0 0.5 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KII86717.1 - 4.1e-05 24.0 0.0 0.00011 22.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KII86717.1 - 0.0004 19.8 0.3 0.0004 19.8 0.3 2.0 3 0 0 3 3 3 1 Thiolase, N-terminal domain Kinesin PF00225.23 KII86718.1 - 3.7e-90 302.2 0.0 7.7e-90 301.2 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII86718.1 - 1.4e-21 77.0 0.0 2.7e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding XkdW PF09636.10 KII86718.1 - 0.67 10.1 6.0 2.1 8.5 0.4 3.7 3 1 1 4 4 4 0 XkdW protein FMO-like PF00743.19 KII86719.1 - 3e-21 75.5 0.0 4e-09 35.4 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII86719.1 - 4.7e-14 52.4 0.0 1.4e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII86719.1 - 6.4e-11 42.0 0.0 3.7e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII86719.1 - 1.5e-07 31.5 0.0 5.5e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KII86719.1 - 5.4e-06 25.8 0.0 0.00034 19.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KII86719.1 - 6e-05 22.8 0.3 0.0025 17.5 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII86719.1 - 6.3e-05 23.0 0.0 0.0014 18.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KII86719.1 - 0.00023 20.6 0.0 0.0035 16.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KII86719.1 - 0.0048 17.4 0.0 4.5 7.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII86719.1 - 0.0073 15.6 0.0 0.0073 15.6 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KII86719.1 - 0.021 14.1 0.0 0.058 12.6 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KII86719.1 - 0.041 12.6 0.0 0.088 11.5 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Glu_dehyd_C PF16912.5 KII86719.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 KII86720.1 - 2.2e-17 63.0 29.5 2.2e-17 63.0 29.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.6 KII86720.1 - 2.6 7.3 6.0 5.4 6.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GFA PF04828.14 KII86722.1 - 1.7e-07 31.4 0.0 1.7e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme BcrAD_BadFG PF01869.20 KII86724.1 - 1.1e-11 44.8 0.0 2e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Ion_trans PF00520.31 KII86726.1 - 1.1e-22 80.4 21.8 1.4e-22 80.1 21.8 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KII86726.1 - 5.2e-11 42.4 6.7 5.2e-11 42.4 6.7 2.6 3 1 0 3 3 3 1 Ion channel Lig_chan PF00060.26 KII86726.1 - 0.0034 17.2 0.3 0.0034 17.2 0.3 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel Ribonuclease_3 PF00636.26 KII86727.1 - 4.6e-42 142.9 0.0 2e-19 70.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KII86727.1 - 2.6e-25 89.1 0.2 5.1e-12 46.1 0.0 4.2 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KII86727.1 - 1.3e-21 76.5 0.0 4.9e-21 74.7 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KII86727.1 - 4.9e-17 62.3 0.0 1.1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII86727.1 - 1.6e-13 50.8 0.0 3.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII86727.1 - 8.9e-12 45.3 0.0 1.9e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Asp PF00026.23 KII86728.1 - 1.1e-54 186.0 14.9 1.6e-54 185.5 14.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII86728.1 - 1e-08 35.6 16.1 1.2e-05 25.6 1.0 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII86728.1 - 2.1e-05 25.1 6.6 0.00078 20.0 1.4 3.0 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KII86728.1 - 0.0016 19.0 3.6 0.07 13.7 0.2 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease GTP_CH_N PF12471.8 KII86729.1 - 2.9e-89 298.0 0.0 4.2e-89 297.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KII86729.1 - 1.4e-14 54.0 0.0 2.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II GNAT_acetyltr_2 PF13718.6 KII86732.1 - 4.2e-90 301.1 0.0 8.1e-90 300.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KII86732.1 - 8.8e-89 297.2 1.0 1.5e-88 296.5 1.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KII86732.1 - 1.4e-65 220.4 0.0 5.6e-65 218.5 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KII86732.1 - 8.8e-33 112.1 0.0 2.5e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KII86732.1 - 0.0003 20.6 0.0 0.064 13.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.7 KII86732.1 - 0.099 13.1 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KII86733.1 - 4.3e-35 121.3 31.2 4.3e-35 121.3 31.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII86733.1 - 1.8e-33 116.1 23.7 3.1e-33 115.3 23.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.25 KII86735.1 - 1.5e-31 109.4 0.0 1.1e-26 93.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII86735.1 - 1.1e-18 67.6 0.0 7.9e-17 61.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86735.1 - 7e-08 32.6 0.1 1.1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII86735.1 - 0.00055 19.5 0.1 0.0018 17.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII86735.1 - 0.0062 16.4 0.8 0.054 13.4 0.6 2.2 1 1 1 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII86735.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Hydrolase_4 PF12146.8 KII86736.1 - 6.6e-05 22.3 0.1 0.0063 15.8 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KII86736.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII86736.1 - 0.00039 21.1 4.2 0.00044 20.9 0.6 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII86736.1 - 0.0038 16.9 0.0 0.02 14.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KII86736.1 - 0.0039 16.3 0.1 2.4 7.1 0.0 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF1749) PGAP1 PF07819.13 KII86736.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 KII86736.1 - 0.025 14.2 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Esterase PF00756.20 KII86736.1 - 0.054 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KII86736.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pro_CA PF00484.19 KII86736.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase PRP1_N PF06424.12 KII86740.1 - 4.1e-51 173.3 5.6 4.1e-51 173.3 5.6 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KII86740.1 - 4.2e-22 77.0 41.3 0.015 16.1 0.4 14.3 6 3 10 16 16 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 KII86740.1 - 2.5e-14 53.5 11.7 0.067 13.7 0.1 9.0 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KII86740.1 - 1.1e-12 48.3 10.3 0.0019 18.8 0.0 7.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII86740.1 - 3.7e-06 26.6 3.5 4.3 7.7 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII86740.1 - 8.2e-06 26.1 0.5 11 7.0 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat FAT PF02259.23 KII86740.1 - 5.5e-05 22.5 5.9 0.11 11.7 0.4 4.2 3 1 0 3 3 3 2 FAT domain TPR_12 PF13424.6 KII86740.1 - 0.00037 20.7 6.2 5 7.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII86740.1 - 0.0037 17.4 0.8 61 4.2 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII86740.1 - 0.0071 16.0 0.1 0.25 11.1 0.0 3.3 4 0 0 4 4 4 1 TPR repeat TPR_9 PF13371.6 KII86740.1 - 0.0087 16.2 9.7 9.5 6.5 0.0 5.7 4 1 1 6 6 6 1 Tetratricopeptide repeat F-box-like PF12937.7 KII86741.1 - 5.5e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII86741.1 - 8.9e-05 22.3 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain bZIP_2 PF07716.15 KII86742.1 - 6e-10 39.0 10.4 4e-09 36.4 10.2 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KII86742.1 - 0.0001 22.3 6.4 0.00024 21.2 6.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor CCDC85 PF10226.9 KII86742.1 - 0.023 14.4 1.8 0.034 13.8 1.8 1.2 1 0 0 1 1 1 0 CCDC85 family bZIP_Maf PF03131.17 KII86742.1 - 0.027 15.0 3.4 0.05 14.1 3.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Shugoshin_N PF07558.11 KII86742.1 - 0.034 14.0 0.2 0.066 13.1 0.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 KII86742.1 - 0.075 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 KII86742.1 - 0.1 12.9 1.5 0.17 12.2 1.5 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family Sugar_tr PF00083.24 KII86743.1 - 2.4e-17 63.0 20.3 8e-12 44.7 4.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KII86743.1 - 1.9e-14 53.4 47.6 5.7e-09 35.4 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily G-patch PF01585.23 KII86744.1 - 4e-05 23.4 0.3 7.4e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 G-patch domain F-box-like PF12937.7 KII86745.1 - 0.00053 19.8 0.2 0.00053 19.8 0.2 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KII86745.1 - 0.0017 18.7 10.0 4.6 7.8 0.6 5.1 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KII86745.1 - 0.016 15.2 0.2 10 6.5 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat DUF1203 PF06718.11 KII86745.1 - 0.17 12.1 0.1 0.31 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) PQ-loop PF04193.14 KII86746.1 - 1.6e-32 111.0 8.9 1.7e-19 69.3 3.1 2.8 4 0 0 4 4 4 2 PQ loop repeat PQ-loop PF04193.14 KII86747.1 - 2.9e-32 110.2 11.6 5.1e-19 67.8 2.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Band_7 PF01145.25 KII86748.1 - 5.6e-22 78.6 2.0 7.4e-22 78.2 2.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MutS_III PF05192.18 KII86749.1 - 4.4e-29 102.1 0.0 9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_V PF00488.21 KII86749.1 - 1.2e-25 90.6 0.5 1.2e-17 64.6 0.3 3.6 2 2 0 2 2 2 2 MutS domain V Mito_carr PF00153.27 KII86750.1 - 2.8e-41 139.4 6.7 4e-16 58.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KII86751.1 - 3.2e-71 239.8 0.0 4e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86751.1 - 4.1e-32 111.5 0.0 5.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KII86751.1 - 1.5e-11 44.8 0.8 4.4e-11 43.3 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KII86751.1 - 2.7e-07 29.9 0.2 4.2e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KII86751.1 - 1.4e-05 24.5 0.0 3.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KII86751.1 - 0.016 14.8 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KII86751.1 - 0.02 14.2 0.1 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII86751.1 - 0.043 13.7 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII86751.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC_membrane PF00664.23 KII86752.1 - 8.8e-108 360.1 25.6 1.6e-55 188.7 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII86752.1 - 5.1e-69 231.1 0.1 4.8e-33 114.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII86752.1 - 2.4e-14 53.3 2.9 4.8e-05 22.9 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KII86752.1 - 9.2e-09 34.6 0.4 0.0036 16.2 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KII86752.1 - 1.1e-08 35.3 0.1 0.00094 19.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII86752.1 - 2.5e-07 30.3 0.8 0.033 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KII86752.1 - 1.6e-06 28.4 1.0 0.024 14.9 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KII86752.1 - 5.5e-06 26.9 3.0 0.012 16.0 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KII86752.1 - 1.8e-05 24.1 0.0 0.044 13.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.6 KII86752.1 - 4.4e-05 23.4 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KII86752.1 - 6e-05 23.0 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KII86752.1 - 8.7e-05 22.2 0.3 0.22 11.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 KII86752.1 - 0.00011 22.0 0.6 1 9.1 0.1 3.7 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 KII86752.1 - 0.00041 19.6 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 KII86752.1 - 0.00082 19.9 0.0 0.66 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII86752.1 - 0.0019 18.4 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2628 PF10947.8 KII86752.1 - 0.0064 16.8 0.8 0.021 15.2 0.1 2.2 2 0 0 2 2 1 1 Protein of unknown function (DUF2628) PRK PF00485.18 KII86752.1 - 0.0071 16.1 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 KII86752.1 - 0.014 15.6 8.8 1.4 9.2 0.2 4.2 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KII86752.1 - 0.014 15.4 0.1 6 6.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KII86752.1 - 0.019 15.2 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KII86752.1 - 0.024 14.7 0.0 8.3 6.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KII86752.1 - 0.027 14.6 0.2 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII86752.1 - 0.027 13.8 0.1 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KII86752.1 - 0.029 14.9 1.3 11 6.5 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KII86752.1 - 0.032 14.7 0.3 21 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KII86752.1 - 0.035 13.6 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KII86752.1 - 0.041 13.6 0.1 11 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KII86752.1 - 0.041 13.8 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KII86752.1 - 0.069 12.3 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 KII86752.1 - 0.081 11.9 0.1 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF815 PF05673.13 KII86752.1 - 0.088 12.0 0.0 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DegV PF02645.16 KII86752.1 - 0.091 12.1 0.6 12 5.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 Motile_Sperm PF00635.26 KII86753.1 - 9.6e-27 93.0 0.2 9.5e-26 89.8 0.0 2.2 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KII86753.1 - 0.0019 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RICTOR_N PF14664.6 KII86754.1 - 8.2e-122 406.8 0.7 1.7e-120 402.5 0.1 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KII86754.1 - 3.1e-43 145.8 0.3 4.9e-39 132.3 0.0 4.4 2 1 2 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KII86754.1 - 6.7e-37 126.2 0.1 1.7e-34 118.5 0.0 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KII86754.1 - 4.5e-31 106.9 0.0 1.1e-27 96.1 0.0 4.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KII86754.1 - 5e-06 26.5 4.7 1.4e-05 25.1 4.7 1.8 1 0 0 1 1 1 1 Hr1 repeat Protoglobin PF11563.8 KII86754.1 - 0.013 15.4 0.4 0.17 11.7 0.2 2.6 2 1 0 2 2 2 0 Protoglobin HEAT PF02985.22 KII86754.1 - 0.018 15.2 0.0 43 4.8 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat F-box PF00646.33 KII86756.1 - 0.00065 19.5 0.2 0.002 18.0 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII86756.1 - 0.00065 19.5 0.3 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like Med18 PF09637.10 KII86756.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Med18 protein ETC_C1_NDUFA4 PF04800.12 KII86758.1 - 7.9e-31 106.2 0.1 1.2e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region RSN1_7TM PF02714.15 KII86759.1 - 2.6e-43 148.3 17.4 4.5e-43 147.5 17.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KII86759.1 - 6.3e-17 62.4 0.0 6.5e-14 52.6 0.0 3.5 4 1 0 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KII86759.1 - 1.5e-15 57.3 0.7 1.5e-15 57.3 0.7 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KII86759.1 - 0.0064 16.6 0.7 0.57 10.4 0.4 2.7 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter GH131_N PF18271.1 KII86760.1 - 1.2e-52 179.2 0.2 1.9e-52 178.5 0.2 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KII86760.1 - 4.2e-10 39.4 13.9 1.2e-09 37.9 13.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF3235 PF11574.8 KII86760.1 - 0.2 12.5 2.7 15 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Herpes_capsid PF06112.11 KII86760.1 - 1.9 8.5 14.1 3.8 7.5 14.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Lipase_GDSL_2 PF13472.6 KII86761.1 - 0.037 14.4 2.8 0.074 13.4 2.8 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family C2 PF00168.30 KII86762.1 - 8.2e-13 48.5 0.0 1.6e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 KII86762.1 - 3.1e-06 27.7 0.1 1.3e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KII86762.1 - 3.6e-05 23.7 0.0 9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KII86762.1 - 0.0021 17.3 0.0 0.0092 15.2 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KII86762.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea F-box-like PF12937.7 KII86763.1 - 2.1e-06 27.5 0.1 6.7e-06 25.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like NT5C PF06941.12 KII86763.1 - 0.18 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) adh_short PF00106.25 KII86764.1 - 1.9e-26 92.8 0.1 2.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86764.1 - 2.5e-22 79.6 0.1 3e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86764.1 - 3.6e-08 33.5 0.0 4.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII86764.1 - 0.0033 17.3 0.1 0.0042 17.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII86764.1 - 0.0059 16.0 0.0 0.0099 15.3 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KII86764.1 - 0.024 14.6 0.1 0.061 13.3 0.1 1.7 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Pneumo_NS1 PF03438.13 KII86765.1 - 0.018 15.2 0.4 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Pneumovirus NS1 protein F-box-like PF12937.7 KII86767.1 - 8.6e-07 28.8 0.2 5.4e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII86767.1 - 0.018 14.9 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 F-box domain CstA PF02554.14 KII86768.1 - 0.006 15.5 2.3 0.0068 15.4 2.3 1.2 1 0 0 1 1 1 1 Carbon starvation protein CstA Sec62 PF03839.16 KII86768.1 - 2.4 7.6 3.8 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 SLATT_3 PF18184.1 KII86768.1 - 3.9 7.6 5.8 0.72 10.0 0.9 2.2 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 DUF3087 PF11286.8 KII86768.1 - 4.2 6.8 5.1 7.1 6.1 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) DUF2069 PF09842.9 KII86768.1 - 6.2 7.1 12.9 0.28 11.4 6.1 2.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2069) Peptidase_M24 PF00557.24 KII86769.1 - 1.3e-49 168.7 0.0 1.7e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KII86769.1 - 1.5e-19 70.0 6.0 3e-19 69.0 6.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII86769.1 - 0.00063 19.8 3.5 0.0015 18.6 3.5 1.7 1 0 0 1 1 1 1 MYND finger Sod_Cu PF00080.20 KII86770.1 - 1.3e-43 148.6 0.7 1.7e-43 148.2 0.7 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 KII86770.1 - 0.049 14.6 1.5 2.1 9.3 0.2 2.3 1 1 0 2 2 2 0 CHRD domain Arginase PF00491.21 KII86771.1 - 1.7e-82 277.1 0.2 2.1e-82 276.8 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KII86771.1 - 0.001 19.4 0.1 0.0017 18.6 0.1 1.3 1 0 0 1 1 1 1 UPF0489 domain Ribosomal_L22 PF00237.19 KII86772.1 - 3.9e-34 117.0 0.1 6.1e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RE_Eco29kI PF09517.10 KII86772.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Eco29kI restriction endonuclease RasGEF PF00617.19 KII86773.1 - 1e-14 55.2 0.1 2.1e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII86773.1 - 6.8e-10 39.1 0.0 2.6e-09 37.2 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif HECT PF00632.25 KII86774.1 - 2.4e-95 319.6 0.0 3.1e-95 319.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KII86774.1 - 2.1e-33 114.0 12.8 1.6e-11 44.1 2.9 3.8 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KII86774.1 - 1.2e-18 67.3 0.0 2.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Sterol_MT_C PF08498.10 KII86775.1 - 1.3e-28 99.1 0.4 2.3e-28 98.3 0.4 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KII86775.1 - 1.1e-18 67.7 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII86775.1 - 3.4e-18 65.9 0.0 5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII86775.1 - 9.8e-17 61.5 0.0 2e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KII86775.1 - 3.6e-13 49.4 0.0 5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KII86775.1 - 3.3e-12 46.5 0.0 4.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86775.1 - 3.4e-12 47.0 0.0 8.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII86775.1 - 5.7e-09 35.7 0.0 1.3e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KII86775.1 - 3.4e-05 23.7 0.0 5.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KII86775.1 - 6.3e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KII86775.1 - 0.00059 19.5 0.1 0.00092 18.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KII86775.1 - 0.00082 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KII86775.1 - 0.0034 16.7 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 KII86775.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 KII86775.1 - 0.011 15.1 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KII86775.1 - 0.022 14.9 0.0 0.092 12.9 0.0 2.0 3 0 0 3 3 3 0 FtsJ-like methyltransferase PrmA PF06325.13 KII86775.1 - 0.032 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 KII86775.1 - 0.051 14.6 0.0 0.14 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KII86775.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 KII86775.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_32 PF13679.6 KII86775.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KII86777.1 - 4.8e-35 121.2 0.0 9.5e-35 120.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86777.1 - 4.8e-20 71.9 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII86777.1 - 0.021 14.7 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KII86777.1 - 0.038 13.3 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KII86777.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KII86777.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Eaf7 PF07904.13 KII86778.1 - 2.5e-13 50.3 0.0 6e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Carm_PH PF17888.1 KII86778.1 - 0.21 12.0 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Carmil pleckstrin homology domain Ufd2P_core PF10408.9 KII86779.1 - 2.4e-224 746.6 0.0 2.9e-224 746.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KII86779.1 - 2.8e-29 101.1 1.3 1.7e-28 98.6 0.8 2.6 2 0 0 2 2 2 1 U-box domain Ribosomal_L35p PF01632.19 KII86780.1 - 2.1e-16 60.1 3.2 2.6e-16 59.9 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 His_Phos_1 PF00300.22 KII86781.1 - 1e-36 126.4 0.1 7.6e-36 123.6 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-AN1 PF01428.16 KII86782.1 - 1e-20 73.6 30.1 2.3e-11 43.7 6.1 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KII86782.1 - 0.06 13.7 21.6 0.28 11.6 3.1 2.8 2 1 1 3 3 3 0 Tc5 transposase C-terminal domain DUF753 PF05444.12 KII86782.1 - 0.51 10.3 13.2 0.84 9.6 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF753) Arginase PF00491.21 KII86784.1 - 1e-81 274.5 0.1 1.3e-81 274.2 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KII86784.1 - 0.0015 18.8 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 UPF0489 domain DUF4436 PF14494.6 KII86785.1 - 4.5e-08 32.7 0.2 6.7e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Peptidase_S10 PF00450.22 KII86786.1 - 6.4e-74 249.8 1.5 1.1e-73 249.1 1.5 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase FAD_binding_3 PF01494.19 KII86787.1 - 8.7e-74 248.8 0.0 1.8e-73 247.8 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KII86787.1 - 2.7e-08 33.4 1.3 1.7e-05 24.3 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII86787.1 - 1.3e-06 27.8 0.2 1.9e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KII86787.1 - 0.00011 22.7 0.2 0.81 10.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII86787.1 - 0.00055 20.1 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KII86787.1 - 0.0012 17.6 0.2 0.0035 16.1 0.0 1.8 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 KII86787.1 - 0.003 17.0 0.2 0.0061 16.0 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KII86787.1 - 0.0053 15.9 0.1 0.0079 15.3 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KII86787.1 - 0.019 14.2 0.0 0.088 12.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII86787.1 - 0.02 14.5 0.7 0.31 10.6 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase F-box-like PF12937.7 KII86788.1 - 5.8e-13 48.5 2.4 1.4e-12 47.3 2.4 1.7 1 0 0 1 1 1 1 F-box-like LigT_PEase PF02834.16 KII86788.1 - 0.023 14.9 0.1 0.079 13.2 0.0 1.9 2 0 0 2 2 2 0 LigT like Phosphoesterase F-box PF00646.33 KII86788.1 - 0.41 10.6 2.6 3 7.8 2.6 2.4 1 1 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.19 KII86789.1 - 1.6e-66 224.9 0.0 2.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII86789.1 - 3.3e-08 33.1 1.4 9.5e-07 28.3 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII86789.1 - 4.8e-07 29.5 0.0 7.1e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII86789.1 - 2.4e-06 28.0 0.8 0.0065 17.0 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII86789.1 - 2.8e-06 26.7 1.2 2.8e-06 26.7 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KII86789.1 - 1.5e-05 24.3 0.8 2.3e-05 23.7 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KII86789.1 - 4e-05 22.5 0.7 7e-05 21.7 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KII86789.1 - 7.4e-05 22.9 0.9 0.00021 21.5 0.4 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII86789.1 - 0.00033 20.0 0.2 0.00075 18.8 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KII86789.1 - 0.0024 17.2 0.1 0.0037 16.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KII86789.1 - 0.015 15.4 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KII86789.1 - 0.026 14.1 3.2 0.033 13.8 1.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KII86789.1 - 0.044 12.6 0.7 0.066 12.0 0.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KII86789.1 - 0.072 12.4 0.6 0.16 11.2 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KII86789.1 - 0.073 12.1 0.6 0.13 11.3 0.6 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KII86789.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KII86789.1 - 0.12 12.0 1.0 0.27 10.9 1.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF5461 PF17545.2 KII86789.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5461) NicO PF03824.16 KII86790.1 - 1.7e-45 155.6 9.7 2e-44 152.0 2.2 2.5 2 1 0 2 2 2 2 High-affinity nickel-transport protein DER1 PF04511.15 KII86791.1 - 1.3e-46 159.0 5.6 1.5e-46 158.7 5.6 1.0 1 0 0 1 1 1 1 Der1-like family F-box-like PF12937.7 KII86792.1 - 1.6e-11 43.9 5.7 4.3e-11 42.5 5.7 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII86792.1 - 0.025 15.0 1.1 15 6.1 0.2 4.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) 4HBT PF03061.22 KII86793.1 - 1.6e-12 47.6 0.7 2.7e-12 46.9 0.7 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KII86793.1 - 0.00037 20.6 0.1 0.00052 20.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) RNase_H PF00075.24 KII86794.1 - 2.5e-05 24.5 0.0 2.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.27 KII86795.1 - 2.2e-07 30.6 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NDK PF00334.19 KII86797.1 - 4.7e-15 55.8 0.0 1.3e-14 54.4 0.0 1.7 1 1 0 1 1 1 1 Nucleoside diphosphate kinase AAA_lid_2 PF17863.1 KII86797.1 - 0.0062 16.4 0.7 0.022 14.6 0.7 2.0 1 0 0 1 1 1 1 AAA lid domain Tam41_Mmp37 PF09139.11 KII86798.1 - 4.3e-109 364.9 0.0 4.9e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial FA_desaturase PF00487.24 KII86799.1 - 2.6e-15 57.0 22.1 2.6e-15 57.0 22.1 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII86799.1 - 2.9e-13 49.8 0.0 5.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF413 PF04219.12 KII86800.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF UBN_AB PF14075.6 KII86801.1 - 0.29 10.8 4.4 0.77 9.4 0.4 2.3 2 1 0 2 2 2 0 Ubinuclein conserved middle domain ABC_membrane PF00664.23 KII86803.1 - 6.8e-115 383.4 26.0 7.2e-59 199.7 8.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII86803.1 - 1.9e-67 226.0 0.0 1.1e-32 113.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII86803.1 - 4.3e-13 49.2 6.6 7.9e-05 22.2 0.9 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KII86803.1 - 1.1e-07 31.1 1.7 0.0023 16.8 0.1 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 KII86803.1 - 8.9e-07 29.0 0.0 0.0084 16.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KII86803.1 - 1.4e-06 28.6 0.4 0.014 15.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KII86803.1 - 1.8e-06 27.6 1.7 0.05 13.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KII86803.1 - 7.3e-06 26.5 2.8 0.024 15.0 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KII86803.1 - 1.1e-05 24.8 0.0 0.068 12.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 KII86803.1 - 9.7e-05 22.2 0.7 0.56 9.9 0.3 3.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KII86803.1 - 0.00012 21.7 0.6 0.2 11.2 0.0 3.5 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 KII86803.1 - 0.00016 21.0 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KII86803.1 - 0.00022 21.2 0.0 0.77 9.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KII86803.1 - 0.00066 20.2 0.0 0.52 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KII86803.1 - 0.0011 19.2 3.1 2.4 8.4 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KII86803.1 - 0.0015 18.3 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KII86803.1 - 0.0021 18.2 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 KII86803.1 - 0.0039 16.9 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KII86803.1 - 0.0053 16.8 0.0 4.2 7.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KII86803.1 - 0.012 15.9 0.0 3 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KII86803.1 - 0.02 14.2 0.2 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 KII86803.1 - 0.024 14.7 0.5 13 5.8 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 KII86803.1 - 0.028 13.8 0.0 3.2 7.1 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 KII86803.1 - 0.032 14.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 KII86803.1 - 0.042 14.3 0.1 19 5.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KII86803.1 - 0.052 13.1 0.0 9.8 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KII86803.1 - 0.055 13.6 0.0 8.1 6.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KII86803.1 - 0.057 13.1 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KII86803.1 - 0.073 12.2 0.1 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 KII86803.1 - 0.082 13.4 0.1 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII86803.1 - 0.13 12.7 0.0 13 6.2 0.0 2.9 3 0 0 3 3 2 0 RNA helicase DUF3987 PF13148.6 KII86803.1 - 0.14 11.2 0.1 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FAD_binding_1 PF00667.20 KII86804.1 - 4e-56 190.1 0.0 2.5e-55 187.5 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KII86804.1 - 4.8e-30 104.6 0.4 9.1e-30 103.7 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KII86804.1 - 5.4e-21 75.3 0.0 1.7e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain She9_MDM33 PF05546.11 KII86805.1 - 1.2e-76 256.9 10.9 1.7e-76 256.5 10.9 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Peptidase_S46 PF10459.9 KII86805.1 - 0.078 11.6 5.5 0.083 11.5 5.5 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1414 PF07208.11 KII86805.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) PIN_12 PF16289.5 KII86805.1 - 0.18 12.3 1.1 0.29 11.6 1.1 1.3 1 0 0 1 1 1 0 PIN domain DUF445 PF04286.12 KII86805.1 - 0.53 10.0 6.7 0.86 9.3 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Uso1_p115_C PF04871.13 KII86805.1 - 6.4 7.2 10.5 0.85 10.0 4.8 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIT PF01230.23 KII86806.1 - 5.3e-16 59.1 0.2 8.5e-16 58.5 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KII86806.1 - 5.3e-10 39.8 0.0 7.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KII86806.1 - 0.0031 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Na_Ca_ex PF01699.24 KII86807.1 - 3.1e-18 66.2 42.6 3.8e-12 46.4 11.7 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 KII86807.1 - 2.7e-14 53.6 32.4 3.2e-13 50.2 12.6 4.3 3 0 0 3 3 3 2 Inner membrane component domain PPP4R2 PF09184.11 KII86807.1 - 1.3 8.5 4.4 2.1 7.8 4.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KII86807.1 - 6.7 4.8 6.2 9.4 4.3 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family ERG4_ERG24 PF01222.17 KII86809.1 - 1e-138 462.7 4.3 1.2e-138 462.5 4.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KII86809.1 - 5.2e-06 26.1 0.2 5.2e-06 26.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KII86809.1 - 7.3e-05 23.1 2.1 0.00014 22.2 0.0 2.6 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KII86809.1 - 0.0001 22.6 0.1 0.002 18.5 0.0 2.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FANCI_HD1 PF14679.6 KII86809.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 FANCI helical domain 1 Hydrolase_6 PF13344.6 KII86810.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII86810.1 - 2.2e-09 37.2 0.1 4.9e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KII86810.1 - 0.027 14.8 0.1 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.23 KII86811.1 - 2.3e-23 82.5 1.4 4.8e-23 81.4 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KII86811.1 - 0.00023 21.2 0.0 0.0007 19.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like PNRC PF15365.6 KII86812.1 - 1.5 8.7 10.9 2.4 8.1 1.0 3.3 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator motif Nop PF01798.18 KII86814.1 - 8.1e-85 283.9 0.0 8.1e-85 283.9 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KII86814.1 - 3.5e-21 75.4 1.0 3.5e-21 75.4 1.0 2.2 2 1 0 2 2 2 1 NOP5NT (NUC127) domain HTH_5 PF01022.20 KII86814.1 - 0.098 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Glyco_hydro_15 PF00723.21 KII86815.1 - 2.7e-96 323.1 1.0 3.2e-96 322.9 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KII86815.1 - 3.4e-30 103.8 0.8 6.8e-30 102.8 0.8 1.5 1 0 0 1 1 1 1 Starch binding domain peroxidase PF00141.23 KII86816.1 - 3.4e-33 115.3 0.0 4.7e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KII86816.1 - 2.9e-15 56.0 0.0 6.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region zf-MYND PF01753.18 KII86817.1 - 2.4e-07 30.7 8.0 1e-06 28.7 8.0 2.2 1 1 0 1 1 1 1 MYND finger YjeF_N PF03853.15 KII86818.1 - 2.2e-38 131.8 0.0 2.7e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 KII86818.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_hydro_16 PF00722.21 KII86819.1 - 0.0038 16.7 0.1 0.0065 16.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KII86820.1 - 0.00019 21.0 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HAD_2 PF13419.6 KII86822.1 - 9.3e-19 68.2 0.0 5.2e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII86822.1 - 1.4e-13 51.6 0.0 8.2e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII86822.1 - 1.9e-05 24.6 0.1 4.9e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like ABC_tran PF00005.27 KII86823.1 - 8.1e-43 146.2 0.0 3.8e-26 92.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII86823.1 - 1.2e-42 146.5 29.7 5.4e-22 78.7 9.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KII86823.1 - 3.5e-11 43.0 0.6 0.016 14.7 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KII86823.1 - 5.3e-06 26.1 0.2 0.035 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KII86823.1 - 7.7e-06 26.5 0.1 0.0025 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII86823.1 - 9.8e-06 26.0 0.5 0.014 15.7 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KII86823.1 - 8.8e-05 22.2 0.1 0.23 11.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 KII86823.1 - 0.00011 21.4 0.0 0.0038 16.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KII86823.1 - 0.0017 18.7 0.0 4.2 7.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KII86823.1 - 0.0024 18.0 0.2 0.063 13.4 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KII86823.1 - 0.0026 17.3 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KII86823.1 - 0.011 15.7 0.1 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KII86823.1 - 0.016 15.3 0.7 0.49 10.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KII86823.1 - 0.019 14.3 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 KII86823.1 - 0.021 13.6 0.3 0.28 9.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 KII86823.1 - 0.022 14.5 0.0 5 6.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KII86823.1 - 0.077 13.4 0.1 21 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.15 KII86823.1 - 0.099 12.6 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_ATPase PF09818.9 KII86823.1 - 0.12 11.2 0.9 10 4.8 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 KII86823.1 - 0.12 12.1 0.2 2.8 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KII86823.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Pox_A32 PF04665.12 KII86823.1 - 0.14 11.6 0.6 4.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 KII86823.1 - 0.14 11.1 1.2 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KII86823.1 - 0.26 11.2 3.6 5.7 6.8 0.1 3.0 3 0 0 3 3 3 0 NTPase AAA_21 PF13304.6 KII86823.1 - 0.31 10.8 6.5 57 3.4 0.1 4.2 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KII86823.1 - 0.36 10.8 1.1 40 4.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KII86823.1 - 0.37 10.3 2.0 3.2 7.3 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored_FMN PF00724.20 KII86825.1 - 2.2e-72 244.2 0.0 2.6e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KII86825.1 - 0.011 15.5 0.1 0.043 13.6 0.1 2.0 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) PRK PF00485.18 KII86825.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family F-box PF00646.33 KII86827.1 - 7e-05 22.6 1.2 0.00018 21.3 0.2 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KII86827.1 - 0.027 14.4 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KII86828.1 - 4.6e-05 23.2 0.1 0.00021 21.1 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII86829.1 - 8.9e-05 22.3 0.1 0.00024 20.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like BTB PF00651.31 KII86832.1 - 0.0066 16.7 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain SLT_L PF14718.6 KII86833.1 - 0.075 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain BTB PF00651.31 KII86834.1 - 2.7e-06 27.6 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain RR_TM4-6 PF06459.12 KII86834.1 - 0.16 11.8 6.8 0.2 11.4 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 KII86834.1 - 0.19 11.0 2.3 0.25 10.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NARP1 PF12569.8 KII86834.1 - 0.44 9.4 16.9 0.63 8.9 16.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 KII86834.1 - 0.77 10.2 7.6 2.3 8.6 8.0 1.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Silic_transp PF03842.13 KII86834.1 - 7.2 4.8 4.9 9.8 4.3 4.9 1.1 1 0 0 1 1 1 0 Silicon transporter BTB PF00651.31 KII86835.1 - 4.5e-06 26.9 0.0 7.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TAF PF02969.17 KII86836.1 - 7.3e-25 86.9 0.1 1.2e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KII86836.1 - 7.5e-15 55.0 0.2 2.7e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 KII86836.1 - 0.0016 18.8 0.1 0.0035 17.7 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KII86836.1 - 0.021 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KII86836.1 - 0.022 14.8 0.0 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBM_20 PF00686.19 KII86837.1 - 4.6e-25 87.3 0.4 4.6e-25 87.3 0.4 2.4 2 1 0 2 2 2 1 Starch binding domain Presenilin PF01080.17 KII86837.1 - 0.18 10.5 12.1 0.22 10.2 12.1 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 KII86837.1 - 0.52 10.3 6.4 0.58 10.1 6.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Utp14 PF04615.13 KII86837.1 - 3.1 6.3 18.4 3.4 6.1 18.4 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.6 KII86837.1 - 9.7 6.7 21.1 12 6.4 21.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Alpha-amylase_C PF02806.18 KII86838.1 - 7.6e-11 42.3 0.0 2.2e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KII86838.1 - 1.7e-09 37.7 0.1 8.2e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain PRIMA1 PF16101.5 KII86840.1 - 6.7 6.8 11.5 4.2 7.4 0.5 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Abhydrolase_6 PF12697.7 KII86842.1 - 4.7e-07 30.6 2.1 4.7e-07 30.6 2.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII86842.1 - 0.06 13.0 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Aldo_ket_red PF00248.21 KII86843.1 - 1.9e-73 247.2 0.0 2.2e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KII86844.1 - 0.0029 17.5 0.9 0.0059 16.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like HMG_box PF00505.19 KII86845.1 - 2.9e-15 56.4 0.1 4.8e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII86845.1 - 9.4e-14 51.8 0.0 1.9e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KII86845.1 - 0.078 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 QRPTase_N PF02749.16 KII86846.1 - 0.059 13.4 0.6 9.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain ANAPC1 PF12859.7 KII86847.1 - 4.6 7.8 16.0 14 6.3 16.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 NAD_binding_6 PF08030.12 KII86848.1 - 3.3e-20 72.8 0.0 1.8e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KII86848.1 - 1.1e-19 70.7 6.1 3.6e-19 69.1 6.1 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KII86848.1 - 1.3e-11 44.6 0.0 5.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain DUF3306 PF11748.8 KII86848.1 - 0.097 13.5 5.2 0.27 12.1 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Trypan_PARP PF05887.11 KII86848.1 - 4 7.4 20.5 0.1 12.6 13.6 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) F-box-like PF12937.7 KII86849.1 - 5.2e-09 35.9 0.9 1.7e-08 34.2 0.9 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII86849.1 - 0.061 13.8 7.1 6.1 7.4 0.6 4.9 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Gly_transf_sug PF04488.15 KII86850.1 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KII86850.1 - 0.2 11.0 0.2 0.32 10.4 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein zf-CCHC_3 PF13917.6 KII86851.1 - 1.2e-19 69.9 3.8 1.6e-19 69.5 3.8 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KII86851.1 - 0.22 11.7 1.6 0.35 11.0 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_jaz PF12171.8 KII86852.1 - 4.8e-05 23.5 8.7 0.091 13.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KII86852.1 - 0.00065 20.0 19.2 0.32 11.6 0.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 KII86852.1 - 0.0011 19.2 7.8 0.034 14.5 0.4 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII86852.1 - 0.002 18.8 13.2 1.6 9.7 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger ATP-synt_C PF00137.21 KII86854.1 - 1.1e-31 108.9 31.9 3.4e-19 68.9 10.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L6 PF00347.23 KII86855.1 - 5.5e-18 65.4 0.0 7.3e-11 42.6 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 tRNA_bind PF01588.20 KII86856.1 - 3.1e-28 97.7 0.0 5.2e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KII86856.1 - 0.0016 18.7 2.0 0.0018 18.4 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII86856.1 - 0.0047 16.9 0.1 0.031 14.3 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII86856.1 - 0.0047 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.21 KII86857.1 - 0.1 11.8 0.0 0.12 11.5 0.0 1.3 1 1 0 1 1 1 0 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII86858.1 - 4.1e-05 22.9 0.0 4.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HSP20 PF00011.21 KII86861.1 - 2.2e-13 50.2 0.0 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII86861.1 - 2.4e-08 33.4 0.0 1.3e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Aldo_ket_red PF00248.21 KII86862.1 - 1.8e-45 155.4 0.0 4.9e-43 147.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.6 KII86863.1 - 9.5e-26 90.9 0.0 1.5e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII86863.1 - 5e-13 49.4 0.0 1.2e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.14 KII86864.1 - 8.1e-22 77.4 1.2 1.3e-21 76.7 1.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 KII86864.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.3 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 KII86865.1 - 2.9e-21 75.6 0.3 4.9e-21 74.9 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KII86865.1 - 0.17 12.1 2.6 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CBFD_NFYB_HMF PF00808.23 KII86866.1 - 7.8e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII86866.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SAGA-Tad1 PF12767.7 KII86866.1 - 0.61 9.8 3.2 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SEN1_N PF12726.7 KII86867.1 - 3.5e-160 534.8 0.4 3.5e-160 534.8 0.4 1.6 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.6 KII86867.1 - 4.7e-70 236.4 2.3 4.7e-70 236.4 2.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KII86867.1 - 1.2e-57 194.8 0.0 2.6e-57 193.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII86867.1 - 5.4e-10 39.3 0.0 4.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KII86867.1 - 1.6e-09 38.2 0.2 1.9e-08 34.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KII86867.1 - 5.2e-06 26.2 0.2 1.5e-05 24.7 0.2 1.8 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KII86867.1 - 5.8e-05 22.9 0.0 1.2 8.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KII86867.1 - 0.00055 20.5 0.7 0.0014 19.2 0.7 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KII86867.1 - 0.0006 19.9 0.1 0.0018 18.3 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KII86867.1 - 0.00068 19.9 0.1 0.0079 16.5 0.0 2.8 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KII86867.1 - 0.013 15.3 0.1 2.6 7.9 0.0 2.5 1 1 1 2 2 2 0 Helicase HAP1_N PF04849.13 KII86867.1 - 0.057 12.6 6.7 0.11 11.7 6.7 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA PF00004.29 KII86867.1 - 0.12 12.8 2.8 0.68 10.4 2.8 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4612 PF15389.6 KII86867.1 - 1.6 9.8 3.9 14 6.8 3.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4612) PI3K_P85_iSH2 PF16454.5 KII86867.1 - 2.4 7.7 8.0 0.39 10.3 2.5 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Atg14 PF10186.9 KII86867.1 - 6 5.9 10.3 19 4.2 10.3 1.8 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HA2 PF04408.23 KII86868.1 - 2.3e-24 85.7 2.7 4.2e-24 84.9 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KII86868.1 - 8.1e-21 74.2 0.0 2.3e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KII86868.1 - 7.2e-11 42.4 0.1 4e-10 40.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII86868.1 - 2.2e-07 30.8 0.0 5.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII86868.1 - 2.7e-06 27.7 0.0 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII86868.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KII86868.1 - 0.018 15.3 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KII86868.1 - 0.053 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KII86868.1 - 0.077 13.5 8.0 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KII86868.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF1325 PF07039.11 KII86869.1 - 7.5e-39 132.8 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 KII86869.1 - 0.047 14.2 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 Agenet domain DUF5401 PF17380.2 KII86869.1 - 1.2 7.2 3.3 1.6 6.7 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) HSP20 PF00011.21 KII86870.1 - 2.1e-13 50.3 0.2 6.6e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII86870.1 - 1.9e-07 30.5 0.5 3.8e-07 29.6 0.5 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 KII86870.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 GvpH FKBP26_C PF18046.1 KII86870.1 - 0.097 12.8 0.2 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 FKBP26_C-terminal Translin PF01997.16 KII86871.1 - 5.5e-48 163.7 0.0 6.3e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Translin family Fcf2 PF08698.11 KII86872.1 - 2.3e-29 101.6 0.0 5.4e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing SEEEED PF14797.6 KII86872.1 - 0.024 14.8 14.9 0.071 13.3 14.9 1.7 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex AF-4 PF05110.13 KII86872.1 - 0.19 9.8 15.2 0.28 9.2 15.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 KII86872.1 - 5.7 7.7 16.5 0.48 11.1 11.2 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein YTH PF04146.15 KII86873.1 - 1.3e-60 204.2 0.0 3.1e-60 202.9 0.0 1.7 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KII86873.1 - 0.00011 21.9 0.0 0.064 13.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBCA PF02970.16 KII86873.1 - 0.057 13.8 0.5 0.13 12.6 0.3 1.6 2 0 0 2 2 2 0 Tubulin binding cofactor A SLY PF12485.8 KII86873.1 - 3.8 8.2 9.4 0.37 11.5 4.1 2.1 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Glyco_hydro_71 PF03659.14 KII86874.1 - 2.2e-130 434.8 7.7 2.6e-130 434.6 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 BshC PF10079.9 KII86875.1 - 0.25 10.0 0.5 0.45 9.2 0.5 1.3 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DASH_Spc19 PF08287.11 KII86875.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Spc19 HAT_KAT11 PF08214.11 KII86876.1 - 3.6e-43 148.2 0.0 4.8e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein SH3_9 PF14604.6 KII86877.1 - 5.2e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII86877.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Sugar_tr PF00083.24 KII86878.1 - 1.1e-85 288.3 20.4 1.2e-85 288.1 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII86878.1 - 1.6e-29 103.0 46.8 2.5e-24 85.8 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_US9 PF06072.11 KII86878.1 - 0.15 11.9 0.6 0.52 10.2 0.5 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ADH_zinc_N PF00107.26 KII86879.1 - 6.6e-11 42.3 1.1 1.3e-10 41.4 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII86879.1 - 1e-05 26.6 0.0 1.9e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII86879.1 - 6e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cullin PF00888.22 KII86882.1 - 9.3e-188 625.7 16.3 1.4e-187 625.1 16.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KII86882.1 - 4.3e-26 90.7 2.3 4.3e-26 90.7 2.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 KII86882.1 - 0.011 16.2 0.1 0.048 14.2 0.1 2.1 1 0 0 1 1 1 0 Bacteriophage replication protein O MarR_2 PF12802.7 KII86882.1 - 0.032 14.1 0.1 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 MarR family Rrf2 PF02082.20 KII86882.1 - 0.036 14.4 0.8 0.21 11.9 0.4 2.5 3 0 0 3 3 3 0 Transcriptional regulator Ubie_methyltran PF01209.18 KII86883.1 - 8.7e-78 260.8 0.0 1.9e-77 259.8 0.0 1.4 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KII86883.1 - 1.7e-14 54.3 0.0 4.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII86883.1 - 6.4e-12 46.0 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII86883.1 - 7.6e-12 45.3 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII86883.1 - 5.4e-09 36.1 0.0 8.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII86883.1 - 7.1e-09 36.3 0.0 1.3e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KII86883.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MRP-L20 PF12824.7 KII86884.1 - 2.1e-23 83.3 0.3 2.3e-23 83.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 KII86884.1 - 0.011 16.3 0.4 0.02 15.5 0.4 1.7 1 1 0 1 1 1 0 Homeodomain-like domain Neugrin PF06413.11 KII86884.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 1 0 1 1 1 0 Neugrin Malic_M PF03949.15 KII86885.1 - 3e-92 308.6 0.0 3.9e-92 308.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KII86885.1 - 6.5e-63 211.8 0.0 9.9e-63 211.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PH PF00169.29 KII86886.1 - 0.053 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 PH domain SIKE PF05769.11 KII86887.1 - 9.4e-05 22.4 7.5 0.0035 17.3 3.6 2.4 2 0 0 2 2 2 2 SIKE family Nsp1_C PF05064.13 KII86887.1 - 0.011 15.5 0.9 0.026 14.3 0.4 1.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF2959 PF11172.8 KII86887.1 - 0.029 14.5 5.3 0.043 13.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) OmpH PF03938.14 KII86887.1 - 0.69 10.2 5.3 1.1 9.6 5.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) bZIP_1 PF00170.21 KII86887.1 - 3.1 8.0 9.2 0.28 11.3 0.6 3.0 2 1 1 3 3 3 0 bZIP transcription factor Ank_5 PF13857.6 KII86890.1 - 0.00054 20.2 0.0 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KII86890.1 - 0.016 15.7 0.0 9.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 KII86890.1 - 0.025 15.2 0.0 7.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII86890.1 - 0.06 13.9 0.0 0.92 10.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII86890.1 - 0.078 13.6 0.0 31 5.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat PH PF00169.29 KII86891.1 - 0.00021 21.8 0.0 0.00054 20.4 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 KII86891.1 - 0.0083 16.4 0.1 0.039 14.2 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KII86891.1 - 0.051 14.0 0.3 0.17 12.3 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain C2 PF00168.30 KII86892.1 - 2.4e-21 76.0 0.0 7.7e-10 39.0 0.0 3.2 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 KII86892.1 - 0.019 14.4 0.0 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain PHD PF00628.29 KII86893.1 - 0.00042 20.1 6.6 0.0011 18.8 6.6 1.8 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KII86893.1 - 0.067 13.1 5.5 0.14 12.1 5.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KII86893.1 - 0.32 10.9 4.5 0.57 10.1 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 KII86893.1 - 0.38 10.7 3.3 1.4 8.9 3.3 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-PHD-like PF15446.6 KII86893.1 - 4.4 6.9 8.4 1.3 8.6 3.6 2.3 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain AA_permease_2 PF13520.6 KII86894.1 - 2.8e-44 151.6 52.2 3.6e-44 151.3 52.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII86894.1 - 1.6e-22 79.8 40.6 2e-22 79.4 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease F-actin_cap_A PF01267.17 KII86895.1 - 2.8e-104 348.2 0.0 3.2e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ICL PF00463.21 KII86897.1 - 8.1e-255 846.3 0.4 9.2e-255 846.1 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KII86897.1 - 1.5e-08 34.4 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 KII86897.1 - 0.029 14.2 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Glycos_transf_4 PF00953.21 KII86898.1 - 2.4e-31 108.9 7.3 2.4e-31 108.9 7.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 SET PF00856.28 KII86899.1 - 4.4e-14 53.2 0.1 1.1e-12 48.7 0.1 2.0 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 KII86900.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII86900.1 - 8.4e-05 22.3 0.0 0.00094 18.9 0.0 2.0 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 KII86900.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase ECH_1 PF00378.20 KII86905.1 - 6.7e-31 107.5 0.0 8.5e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII86905.1 - 1.3e-11 44.6 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF930 PF06059.12 KII86905.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) DUF2781 PF10914.8 KII86906.1 - 3.9e-41 140.9 9.5 4.6e-41 140.6 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Mersacidin PF16934.5 KII86906.1 - 1.8 8.4 4.5 3.5 7.5 4.5 1.4 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) PROCN PF08083.11 KII86907.1 - 3.2e-232 770.5 10.5 1e-231 768.8 9.1 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KII86907.1 - 1.2e-126 421.0 0.4 2.9e-126 419.7 0.4 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KII86907.1 - 1.2e-87 291.9 2.3 1.2e-87 291.9 2.3 2.4 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KII86907.1 - 2e-85 284.3 2.4 2e-85 284.3 2.4 2.8 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KII86907.1 - 3.5e-73 244.0 0.1 6.6e-73 243.1 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KII86907.1 - 3.8e-46 155.4 0.4 8.1e-46 154.3 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KII86907.1 - 7.7e-41 138.9 0.0 1.6e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KII86907.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SMC_N PF02463.19 KII86908.1 - 7.4e-27 94.2 0.0 1.3e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII86908.1 - 2.2e-17 64.2 12.7 2.2e-17 64.2 12.7 5.2 3 2 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KII86908.1 - 1.3e-11 44.8 8.4 1.3e-11 44.8 8.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KII86908.1 - 1.8e-07 31.3 2.2 0.00096 19.0 0.5 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII86908.1 - 0.00027 20.6 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KII86908.1 - 0.094 13.2 0.1 0.094 13.2 0.1 5.2 3 2 0 3 3 3 0 ABC transporter GST_N_3 PF13417.6 KII86910.1 - 9.8e-14 51.5 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII86910.1 - 5.1e-11 42.7 0.1 1.4e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII86910.1 - 5.8e-06 26.2 0.0 2e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII86910.1 - 0.0031 17.7 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII86910.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KII86910.1 - 0.051 13.9 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KII86910.1 - 0.17 12.6 0.0 1.1 10.1 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain SKN1 PF03935.15 KII86911.1 - 3.4e-203 675.6 8.2 4.1e-203 675.3 8.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GRASP55_65 PF04495.14 KII86912.1 - 4.9e-60 201.8 0.0 4.2e-43 147.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KII86912.1 - 0.00021 21.6 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 KII86912.1 - 0.00032 20.5 0.2 0.0038 17.0 0.0 2.6 3 0 0 3 3 3 1 PDZ domain Zip PF02535.22 KII86912.1 - 0.023 14.0 6.2 0.032 13.5 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter p450 PF00067.22 KII86913.1 - 1.4e-69 235.1 0.0 1.6e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThiF PF00899.21 KII86914.1 - 6.8e-33 114.0 0.0 8.8e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 KII86915.1 - 1.7e-20 73.1 0.0 3.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII86915.1 - 6.2e-07 29.4 10.5 1.3e-06 28.4 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.6 KII86916.1 - 0.00024 21.7 1.6 1.4 9.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_3 PF13812.6 KII86916.1 - 0.018 15.1 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_14 PF13428.6 KII86916.1 - 0.37 11.7 8.0 12 7.0 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 KII86917.1 - 1.2e-05 25.4 0.0 5.3e-05 23.3 0.0 2.0 2 1 0 2 2 2 1 Mur ligase middle domain Peptidase_C48 PF02902.19 KII86918.1 - 1.6e-35 123.0 0.1 9.7e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Dynactin_p62 PF05502.13 KII86919.1 - 1.3e-71 241.9 7.6 5.5e-44 150.7 4.8 2.1 1 1 0 2 2 2 2 Dynactin p62 family zf-4CXXC_R1 PF10497.9 KII86919.1 - 0.52 10.6 8.4 0.33 11.2 5.5 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pet127 PF08634.10 KII86920.1 - 1.4e-105 352.6 0.0 1.9e-105 352.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Arf PF00025.21 KII86921.1 - 1.1e-38 132.4 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KII86921.1 - 1.6e-18 66.8 0.0 2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII86921.1 - 3.4e-14 53.1 0.0 4.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KII86921.1 - 4.7e-08 32.7 0.0 5.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KII86921.1 - 1.5e-07 31.0 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII86921.1 - 4.5e-06 26.7 0.0 6.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KII86921.1 - 1.2e-05 24.7 1.4 6e-05 22.4 0.2 2.0 1 1 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 KII86921.1 - 0.015 15.4 0.3 0.76 9.8 0.9 2.2 1 1 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.27 KII86921.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RPN13_C PF16550.5 KII86922.1 - 1.6e-29 102.4 0.1 2.6e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KII86922.1 - 4.5e-22 78.4 0.0 7.9e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MNSV_P7B PF06692.11 KII86922.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF2205 PF10224.9 KII86923.1 - 8.9e-09 35.2 0.2 1e-08 35.0 0.2 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 KII86923.1 - 0.026 15.1 0.2 0.029 15.0 0.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Endotoxin_C2 PF18449.1 KII86923.1 - 0.033 14.5 1.6 0.27 11.6 0.4 2.1 2 0 0 2 2 2 0 Delta endotoxin XhlA PF10779.9 KII86923.1 - 0.07 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA CLZ PF16526.5 KII86923.1 - 0.099 13.0 1.1 0.11 12.8 1.1 1.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4267 PF14087.6 KII86924.1 - 2.4e-22 79.1 2.4 3e-22 78.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PGPGW PF09656.10 KII86924.1 - 7.3 6.2 9.4 0.62 9.6 0.1 3.2 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) AMP-binding PF00501.28 KII86925.1 - 3.7e-79 266.3 0.0 5.3e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme F-box-like PF12937.7 KII86926.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.3 3 0 0 3 3 3 0 F-box-like AAA_23 PF13476.6 KII86927.1 - 1e-32 114.2 0.0 1e-32 114.2 0.0 7.8 1 1 2 3 3 1 1 AAA domain AAA_15 PF13175.6 KII86927.1 - 6.6e-17 62.3 14.9 2.8e-09 37.1 0.0 4.6 1 1 2 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KII86927.1 - 7.9e-12 45.6 8.9 1.4e-05 25.1 0.1 4.4 3 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII86927.1 - 5.3e-10 39.1 0.0 5.3e-10 39.1 0.0 3.4 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KII86927.1 - 1.6e-06 28.3 0.0 8.1e-06 26.0 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KII86927.1 - 1.2e-05 24.3 109.2 0.0032 16.2 21.9 7.1 5 1 2 7 7 7 4 AAA domain DUF4164 PF13747.6 KII86927.1 - 0.00033 20.9 1.3 0.00033 20.9 1.3 9.6 6 2 2 9 9 6 1 Domain of unknown function (DUF4164) AAA_29 PF13555.6 KII86927.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KII86927.1 - 0.0044 17.5 0.0 0.0044 17.5 0.0 6.4 4 2 1 5 5 4 1 ABC transporter Roc PF08477.13 KII86927.1 - 0.065 13.5 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1131 PF06572.12 KII86927.1 - 0.088 12.5 0.1 0.37 10.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) AAA_16 PF13191.6 KII86927.1 - 0.19 12.1 0.0 0.19 12.1 0.0 5.4 3 2 1 4 4 3 0 AAA ATPase domain AAA_22 PF13401.6 KII86927.1 - 0.96 9.7 0.0 0.96 9.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain GTP_EFTU PF00009.27 KII86927.1 - 2.2 7.8 6.7 0.33 10.5 0.1 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DegQ PF08181.11 KII86927.1 - 3.9 7.7 8.1 3.3 7.9 0.2 3.9 3 0 0 3 3 3 0 DegQ (SacQ) family Fez1 PF06818.15 KII86927.1 - 7.5 6.9 118.8 0.57 10.6 13.0 7.8 2 2 4 6 6 6 0 Fez1 Putative_PNPOx PF01243.20 KII86929.1 - 8.6e-25 86.8 0.0 1.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KII86929.1 - 1e-19 70.3 2.0 1e-19 70.3 2.0 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KII86929.1 - 2.3e-05 24.9 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KII86929.1 - 0.011 15.4 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like Pyridox_ox_2 PF12900.7 KII86929.1 - 0.059 13.4 0.2 0.094 12.7 0.2 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Trimer_CC PF08954.11 KII86929.1 - 0.32 10.6 2.5 5.4 6.7 0.8 3.0 3 0 0 3 3 3 0 Trimerisation motif Kelch_6 PF13964.6 KII86931.1 - 4.6e-18 64.8 3.0 0.001 19.3 0.1 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 KII86931.1 - 4.2e-15 55.0 5.2 0.00033 20.5 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KII86931.1 - 5.2e-15 54.8 0.7 0.00099 18.6 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 KII86931.1 - 8.9e-15 54.3 0.3 0.0044 17.0 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KII86931.1 - 1e-10 41.5 9.6 0.0027 17.7 0.0 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KII86931.1 - 1.1e-07 32.0 8.4 1.1e-05 25.6 0.0 5.9 7 0 0 7 7 7 1 Galactose oxidase, central domain BTB PF00651.31 KII86931.1 - 0.0029 17.8 0.1 0.66 10.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain zf-CRD PF17979.1 KII86933.1 - 3.2e-10 40.3 4.8 6.4e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KII86933.1 - 4.7e-06 26.3 12.8 4.7e-06 26.3 12.8 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII86933.1 - 2.7e-05 24.4 13.4 2.7e-05 24.4 13.4 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII86933.1 - 0.00039 20.2 10.8 0.00039 20.2 10.8 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII86933.1 - 0.0037 17.1 12.0 0.0037 17.1 12.0 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 KII86933.1 - 0.0086 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 PBZ domain zf-Nse PF11789.8 KII86933.1 - 0.34 10.8 3.2 0.94 9.4 3.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KII86933.1 - 0.36 10.7 13.4 0.068 13.0 9.0 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KII86933.1 - 6.4 7.2 14.7 0.43 10.9 8.7 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Herpes_LMP1 PF05297.11 KII86935.1 - 5.4 6.1 5.4 1 8.5 0.7 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Pectinesterase PF01095.19 KII86936.1 - 7.3e-34 116.8 0.8 4.4e-29 101.2 0.8 2.1 1 1 0 2 2 2 2 Pectinesterase Syntaxin_2 PF14523.6 KII86937.1 - 2.2e-22 79.3 6.9 1.1e-21 77.1 3.6 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KII86937.1 - 6e-09 35.8 2.6 1.5e-08 34.5 0.4 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KII86937.1 - 1.8e-06 27.7 11.2 3.8e-06 26.7 11.2 1.6 1 1 0 1 1 1 1 Syntaxin TMPIT PF07851.13 KII86937.1 - 0.012 14.9 2.6 0.34 10.1 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF2730 PF10805.8 KII86937.1 - 0.11 12.6 2.4 5 7.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 KII86937.1 - 0.56 10.6 3.6 44 4.6 0.0 3.9 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 KII86937.1 - 2.6 8.2 8.3 7 6.8 0.7 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KII86937.1 - 3 8.2 8.2 18 5.6 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) F-box-like PF12937.7 KII86938.1 - 0.00016 21.5 0.2 0.0019 18.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 KII86939.1 - 4.9e-69 232.6 0.0 6.1e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86939.1 - 2.8e-42 144.8 0.0 3.6e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII86939.1 - 4.7e-06 26.1 0.0 1.4e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KII86939.1 - 0.0039 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII86939.1 - 0.0046 16.9 0.3 0.82 9.5 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KII86939.1 - 0.012 15.3 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CBF PF03914.17 KII86939.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.4 3 0 0 3 3 3 0 CBF/Mak21 family Seadorna_VP7 PF07387.11 KII86939.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_4 PF08386.10 KII86940.1 - 7.3e-16 58.2 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KII86940.1 - 3e-10 40.2 0.1 8.7e-08 32.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_M16 PF00675.20 KII86941.1 - 1.1e-54 184.5 0.3 5.2e-54 182.3 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KII86941.1 - 1.2e-39 136.3 0.0 3.6e-36 124.9 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Mit_ribos_Mrp51 PF11709.8 KII86941.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit M16C_assoc PF08367.11 KII86941.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M16C associated zf-Nse PF11789.8 KII86942.1 - 1.5e-16 60.0 0.0 2.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KII86942.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII86942.1 - 0.0079 16.2 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII86942.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.12 KII86942.1 - 2.1 8.1 25.3 1 9.1 18.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SIR2 PF02146.17 KII86943.1 - 6.1e-60 202.2 0.0 8.1e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KII86943.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Ebp2 PF05890.12 KII86944.1 - 1.6e-89 300.0 9.0 2e-89 299.7 9.0 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Red1 PF07964.11 KII86944.1 - 0.12 10.6 8.2 0.17 10.1 8.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Oxidored_molyb PF00174.19 KII86945.1 - 6.1e-49 165.9 0.0 1.1e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KII86945.1 - 1e-20 74.2 1.7 1.9e-20 73.3 1.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Velvet PF11754.8 KII86946.1 - 2e-39 136.1 0.0 2.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.8 KII86947.1 - 1.4e-40 139.8 0.0 1.8e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Velvet factor adh_short PF00106.25 KII86948.1 - 1.7e-10 40.7 0.0 3e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86948.1 - 8.2e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sas10 PF09368.10 KII86949.1 - 2e-25 89.0 5.0 2e-25 89.0 5.0 3.1 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KII86949.1 - 4.1e-06 27.3 1.1 1.8e-05 25.3 1.1 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family VIT1 PF01988.19 KII86949.1 - 1.3 8.9 6.8 8.2 6.2 0.3 3.0 3 0 0 3 3 3 0 VIT family INTAP PF16617.5 KII86949.1 - 2.7 8.4 7.9 2.6 8.4 0.2 2.7 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region Asp PF00026.23 KII86951.1 - 9.5e-49 166.5 15.4 2.4e-48 165.2 15.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII86951.1 - 2.4e-06 27.9 14.4 2.3e-05 24.7 0.4 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KII86951.1 - 0.0032 18.0 4.5 0.23 12.1 0.3 3.2 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII86951.1 - 0.028 15.1 9.4 0.16 12.6 1.7 3.1 3 0 0 3 3 3 0 Aspartyl protease adh_short PF00106.25 KII86954.1 - 4.4e-31 107.9 0.0 6.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86954.1 - 4.2e-27 95.2 0.0 5e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86954.1 - 2.6e-11 43.8 0.0 3.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII86954.1 - 0.00029 20.8 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KII86954.1 - 0.05 13.6 0.0 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_C80 PF11713.8 KII86954.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family TPP_enzyme_N PF02776.18 KII86955.1 - 6.7e-35 120.2 0.0 1.3e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KII86955.1 - 2.2e-14 53.5 0.0 7.5e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KII86955.1 - 4.3e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain FANC_SAP PF18081.1 KII86955.1 - 0.13 12.5 1.3 0.29 11.3 0.1 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain FA_desaturase PF00487.24 KII86956.1 - 1.7e-22 80.5 22.5 3.7e-22 79.4 22.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Pkinase PF00069.25 KII86957.1 - 1.2e-13 51.1 0.0 2.5e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII86957.1 - 3.2e-07 29.9 0.0 2.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII86957.1 - 0.00042 19.2 0.0 0.00072 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Lar_N PF09861.9 KII86957.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Oxidored_FMN PF00724.20 KII86958.1 - 1.1e-99 334.0 0.0 1.2e-99 333.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FA_desaturase PF00487.24 KII86959.1 - 1.3e-21 77.6 25.7 3.4e-21 76.3 25.8 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Exo_endo_phos PF03372.23 KII86960.1 - 8.7e-06 25.4 0.0 3.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KII86960.1 - 0.00084 19.2 6.3 0.035 14.0 1.5 3.2 3 1 0 3 3 3 2 Endonuclease-reverse transcriptase Fe-ADH_2 PF13685.6 KII86960.1 - 0.0079 15.9 0.8 0.016 14.9 0.8 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ABC_membrane PF00664.23 KII86961.1 - 6e-51 173.7 24.9 2.3e-25 89.8 5.8 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 KII86961.1 - 1.2e-43 149.0 0.0 8e-26 91.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII86961.1 - 5e-11 42.4 2.1 0.028 13.8 0.0 4.3 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII86961.1 - 2.4e-06 28.1 0.3 0.027 14.8 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KII86961.1 - 4.4e-06 26.3 0.9 0.008 15.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KII86961.1 - 6.6e-06 25.4 0.2 0.00057 19.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 KII86961.1 - 7.1e-06 26.7 0.3 0.00056 20.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII86961.1 - 0.00011 21.8 0.0 0.39 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KII86961.1 - 0.00022 21.1 4.3 0.34 10.7 0.1 4.2 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Adeno_IVa2 PF02456.15 KII86961.1 - 0.0004 19.3 0.1 0.0036 16.1 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_22 PF13401.6 KII86961.1 - 0.0011 19.2 0.3 0.63 10.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII86961.1 - 0.0018 17.8 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KII86961.1 - 0.0031 17.6 1.6 0.15 12.1 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII86961.1 - 0.0048 16.3 1.3 0.66 9.3 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KII86961.1 - 0.01 15.9 0.7 0.95 9.6 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KII86961.1 - 0.012 16.1 0.0 1.7 9.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 KII86961.1 - 0.017 14.8 0.1 4.7 6.9 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein DEAD PF00270.29 KII86961.1 - 0.034 13.9 0.3 11 5.7 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KII86961.1 - 0.036 13.8 0.1 0.64 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KII86961.1 - 0.043 13.8 0.2 13 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KII86961.1 - 0.047 13.6 0.8 12 5.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF2075 PF09848.9 KII86961.1 - 0.064 12.5 0.1 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 KII86961.1 - 0.082 12.7 0.4 12 5.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 KII86961.1 - 0.093 12.6 0.1 1.1 9.2 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 KII86961.1 - 0.12 11.8 1.1 11 5.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 KII86961.1 - 0.13 12.1 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 KII86961.1 - 0.18 11.8 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Dynamin_N PF00350.23 KII86961.1 - 0.19 11.8 0.9 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 KII86961.1 - 0.19 11.3 3.9 0.3 10.7 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KII86961.1 - 0.2 12.1 0.1 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABA_GPCR PF12430.8 KII86961.1 - 0.28 10.9 4.5 5.6 6.7 0.8 2.7 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor TrwB_AAD_bind PF10412.9 KII86961.1 - 0.38 9.6 1.8 4.6 6.0 0.5 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KII86961.1 - 0.45 10.4 2.8 2.7 7.9 0.1 2.7 3 0 0 3 3 2 0 NTPase NACHT PF05729.12 KII86961.1 - 0.99 9.3 3.6 6.6 6.6 0.2 2.9 3 0 0 3 3 3 0 NACHT domain COesterase PF00135.28 KII86963.1 - 9.9e-84 282.0 0.0 1.2e-83 281.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII86963.1 - 9e-06 25.7 1.1 1.5e-05 25.0 0.1 1.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII86963.1 - 0.0072 15.8 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KII86963.1 - 0.1 12.2 1.6 0.65 9.6 0.1 2.5 3 0 0 3 3 3 0 Putative esterase Macoilin PF09726.9 KII86964.1 - 0.29 9.7 6.4 0.35 9.4 6.4 1.1 1 0 0 1 1 1 0 Macoilin family CALCOCO1 PF07888.11 KII86966.1 - 0.0049 15.8 0.6 0.0068 15.3 0.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 KII86966.1 - 0.012 15.9 1.4 0.061 13.6 1.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 KII86966.1 - 0.022 13.6 0.8 0.031 13.2 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_HK97_TLTM PF06120.11 KII86966.1 - 0.035 13.3 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein APG6_N PF17675.1 KII86966.1 - 0.036 14.6 0.0 0.064 13.8 0.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region SbcD_C PF12320.8 KII86966.1 - 0.038 14.3 0.1 0.23 11.8 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain NPV_P10 PF05531.12 KII86966.1 - 0.19 12.2 1.4 0.61 10.6 0.6 2.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Trimer_CC PF08954.11 KII86966.1 - 0.25 10.9 3.6 5.7 6.6 0.1 2.6 1 1 0 2 2 2 0 Trimerisation motif POP1 PF06978.11 KII86967.1 - 4e-46 157.6 20.6 6.1e-26 91.7 1.5 2.7 2 1 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KII86967.1 - 6.6e-32 109.7 0.6 6.6e-32 109.7 0.6 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KII86967.1 - 0.03 13.7 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KII86967.1 - 0.033 14.1 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Iso_dh PF00180.20 KII86969.1 - 1.6e-87 293.9 0.0 1.9e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_transf_28 PF03033.20 KII86970.1 - 5e-25 88.1 0.0 1.6e-24 86.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KII86970.1 - 6.6e-07 28.5 0.0 1.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 KII86970.1 - 4.4e-06 27.2 0.1 0.00014 22.3 0.1 2.8 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 KII86970.1 - 4.3e-05 23.4 0.0 0.48 10.3 0.0 3.1 3 0 0 3 3 3 2 GRAM domain Oxidored_FMN PF00724.20 KII86971.1 - 2.7e-60 204.5 0.0 3.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_S19e PF01090.19 KII86972.1 - 1.3e-57 193.4 0.1 1.5e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e NOA36 PF06524.12 KII86972.1 - 0.071 12.4 6.0 0.081 12.2 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein Zn_clus PF00172.18 KII86974.1 - 8.6e-07 29.0 8.7 1.8e-06 27.9 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII86974.1 - 0.079 12.0 0.0 0.31 10.0 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain ELH PF02323.15 KII86974.1 - 0.099 12.0 0.9 0.18 11.1 0.9 1.3 1 0 0 1 1 1 0 Egg-laying hormone precursor Mito_carr PF00153.27 KII86976.1 - 5.1e-26 90.4 6.9 9.5e-14 51.1 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KII86977.1 - 2.3e-29 102.2 0.0 4.4e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII86977.1 - 9e-10 38.5 10.4 2.2e-09 37.3 10.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KII86978.1 - 3.9e-34 118.1 34.5 3.9e-34 118.1 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KII86980.1 - 5.1e-61 206.8 0.0 6.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KII86981.1 - 1.4e-06 28.1 1.0 3.1e-06 27.0 1.0 1.6 1 0 0 1 1 1 1 F-box-like GFO_IDH_MocA PF01408.22 KII86983.1 - 2.6e-16 60.5 0.0 4.7e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Acetyltransf_7 PF13508.7 KII86984.1 - 0.0029 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII86984.1 - 0.036 14.1 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 KII86985.1 - 1.7e-26 92.9 0.1 2.2e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86985.1 - 1.9e-18 66.9 0.1 2.3e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86985.1 - 4.6e-07 29.9 0.0 6.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII86985.1 - 0.00022 21.2 0.1 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII86985.1 - 0.00087 18.8 0.0 0.002 17.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII86985.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KII86986.1 - 1.9e-26 92.7 0.1 2.5e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86986.1 - 2.7e-20 72.9 0.0 3.4e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII86986.1 - 2.2e-07 31.0 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII86986.1 - 0.00056 19.8 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KII86986.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF4336 PF14234.6 KII86987.1 - 3.6e-15 56.0 0.1 3.9e-08 32.9 0.0 3.7 1 1 2 3 3 3 2 Domain of unknown function (DUF4336) Lactamase_B PF00753.27 KII86988.1 - 4.1e-13 49.8 5.2 5.8e-13 49.3 5.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KII86988.1 - 0.00033 20.2 0.1 0.00056 19.5 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.25 KII86990.1 - 2.7e-44 151.0 2.1 3.3e-44 150.7 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII86990.1 - 1e-30 107.0 0.3 1.3e-30 106.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KII86990.1 - 4.9e-05 22.9 0.4 8.8e-05 22.1 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KII86990.1 - 0.0023 17.9 0.6 0.0092 16.0 0.3 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KII86990.1 - 0.005 17.1 0.1 0.0089 16.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 KII86990.1 - 0.018 14.6 0.2 0.028 14.0 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KII86990.1 - 0.044 12.9 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KII86990.1 - 0.061 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAE PF03283.13 KII86990.1 - 0.19 10.8 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Acyl-CoA_dh_1 PF00441.24 KII86991.1 - 8.6e-41 139.6 3.7 1.6e-40 138.8 3.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KII86991.1 - 3.1e-27 95.5 0.0 6.3e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KII86991.1 - 6.5e-25 87.2 0.0 1.4e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KII86991.1 - 3e-15 56.7 0.9 5e-15 55.9 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 KII86993.1 - 7.6e-85 285.0 0.0 9.3e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII86993.1 - 3e-16 60.1 0.3 1.1e-15 58.3 0.3 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MAF_flag10 PF01973.18 KII86993.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 p450 PF00067.22 KII86994.1 - 7.6e-73 245.8 0.0 9.1e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2367 PF10164.9 KII86995.1 - 5.1e-06 26.9 9.3 7.8e-06 26.3 9.3 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.9 KII86995.1 - 0.061 13.6 5.5 0.076 13.3 5.5 1.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain ADH_zinc_N PF00107.26 KII86996.1 - 1.8e-12 47.4 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII86996.1 - 3.7e-06 28.0 0.0 7.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII86996.1 - 4.3e-06 26.6 1.6 0.00011 22.1 0.6 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain zf-RING_2 PF13639.6 KII86997.1 - 2.2e-13 50.3 4.3 3.4e-13 49.7 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KII86997.1 - 5.8e-09 35.5 1.0 1e-08 34.7 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KII86997.1 - 8.6e-09 35.6 4.3 1.6e-08 34.7 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KII86997.1 - 1.3e-08 34.5 3.4 2e-08 33.9 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII86997.1 - 2e-08 34.0 2.9 3.2e-08 33.3 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII86997.1 - 9.9e-08 31.8 2.5 1.5e-07 31.2 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KII86997.1 - 8.5e-06 25.5 2.2 1.4e-05 24.9 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII86997.1 - 7.3e-05 22.7 1.0 0.00014 21.8 1.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KII86997.1 - 7.6e-05 22.7 1.4 0.00013 21.9 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KII86997.1 - 0.0038 17.0 2.4 0.0066 16.3 2.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KII86997.1 - 0.0042 16.7 2.0 0.0075 15.9 2.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KII86997.1 - 0.063 13.1 4.9 0.12 12.2 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KII86997.1 - 0.096 13.0 2.6 0.17 12.2 2.6 1.3 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 KII86997.1 - 0.17 12.0 4.0 0.3 11.2 4.0 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_5 PF17121.5 KII86997.1 - 0.49 10.3 6.7 0.14 12.1 2.5 2.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KII86997.1 - 1.6 8.7 4.1 2.7 8.0 4.1 1.4 1 0 0 1 1 1 0 PHD-finger ETF PF01012.21 KII86998.1 - 5.3e-43 147.0 0.9 7e-43 146.6 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Glyco_hydro_18 PF00704.28 KII86999.1 - 1.7e-58 198.9 0.8 2.1e-58 198.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KII87001.1 - 2.3e-15 57.1 1.2 4.6e-15 56.1 1.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GMC_oxred_N PF00732.19 KII87002.1 - 2.8e-59 200.9 0.0 3.7e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII87002.1 - 1.9e-33 116.0 0.0 3.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KII87002.1 - 0.00025 20.3 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KII87002.1 - 0.00043 19.4 0.0 0.00067 18.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KII87002.1 - 0.00058 19.1 0.5 0.011 14.9 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KII87002.1 - 0.0026 17.4 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII87002.1 - 0.0027 17.0 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII87002.1 - 0.0057 16.9 0.1 0.016 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII87002.1 - 0.0094 15.2 1.2 0.63 9.2 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PHZA_PHZB PF03284.13 KII87002.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B HI0933_like PF03486.14 KII87002.1 - 0.14 10.8 0.7 0.24 10.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Ribosom_S12_S23 PF00164.25 KII87003.1 - 5.1e-32 109.9 4.1 6.8e-32 109.5 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 REPA_OB_2 PF16900.5 KII87003.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Replication protein A OB domain PH_4 PF15404.6 KII87004.1 - 3.6e-21 75.8 0.0 1.3e-16 61.0 0.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 KII87004.1 - 0.034 14.5 0.6 18 5.7 0.0 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain PRIMA1 PF16101.5 KII87004.1 - 3.2 7.8 4.6 7.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 AOX PF01786.17 KII87005.1 - 2.2e-97 324.8 0.7 3.7e-97 324.1 0.7 1.3 1 0 0 1 1 1 1 Alternative oxidase ICMT PF04140.14 KII87005.1 - 0.083 13.3 0.2 0.18 12.2 0.2 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family HTH_Tnp_Tc5 PF03221.16 KII87006.1 - 1.2e-11 44.5 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Secretin_N_2 PF07655.13 KII87007.1 - 0.052 14.1 2.8 1.7 9.2 0.0 2.5 2 1 0 2 2 2 0 Secretin N-terminal domain DUF4663 PF15668.5 KII87007.1 - 0.19 10.8 6.3 0.26 10.3 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) CDC27 PF09507.10 KII87007.1 - 2.2 7.6 11.2 2.8 7.2 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOG2 PF10428.9 KII87007.1 - 3.6 6.7 11.1 4.4 6.4 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SRP-alpha_N PF04086.13 KII87007.1 - 3.9 7.3 15.4 5.2 6.9 15.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1387 PF07139.11 KII87007.1 - 8.7 6.0 7.6 15 5.2 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF2462 PF09495.10 KII87008.1 - 6e-21 75.0 11.9 7.8e-21 74.6 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Cytomega_UL20A PF05984.12 KII87008.1 - 0.11 12.8 1.1 0.15 12.4 0.9 1.4 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein Ntox4 PF15541.6 KII87008.1 - 0.11 12.8 0.3 0.18 12.2 0.2 1.4 1 1 0 1 1 1 0 Bacterial toxin 4 NAD_binding_10 PF13460.6 KII87009.1 - 7e-14 52.1 0.0 1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII87009.1 - 9.1e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KII87009.1 - 7.8e-12 45.2 0.2 2.6e-11 43.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII87009.1 - 3.6e-11 42.6 0.0 7.2e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KII87009.1 - 8.4e-11 41.5 0.1 7e-09 35.2 0.0 2.5 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KII87009.1 - 1.2e-06 27.9 0.2 0.00049 19.3 0.0 2.4 1 1 2 3 3 3 3 Male sterility protein GDP_Man_Dehyd PF16363.5 KII87009.1 - 3e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 KII87009.1 - 0.00065 19.3 0.0 0.0045 16.6 0.0 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KII87009.1 - 0.00092 18.4 0.0 0.0024 17.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KII87009.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII87009.1 - 0.016 15.1 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.17 KII87009.1 - 0.14 12.7 0.0 0.59 10.8 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Tom22 PF04281.13 KII87010.1 - 5.1e-39 133.2 0.9 6.2e-39 132.9 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 SR-25 PF10500.9 KII87010.1 - 1.4 8.5 8.7 2.4 7.7 8.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.18 KII87011.1 - 6.4e-07 29.4 9.5 1.1e-06 28.7 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII87011.1 - 3.1e-05 23.2 0.0 4.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5510 PF17629.2 KII87012.1 - 0.29 11.1 3.0 0.61 10.1 3.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5510) FixS PF03597.15 KII87012.1 - 9.6 6.0 6.7 0.41 10.4 0.6 1.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type baeRF_family5 PF18846.1 KII87013.1 - 0.35 11.1 5.1 2.1 8.6 2.1 2.3 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 SQS_PSY PF00494.19 KII87014.1 - 1.4e-50 172.3 1.1 1.6e-50 172.0 1.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase zf-C2H2_2 PF12756.7 KII87016.1 - 0.092 13.1 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KII87016.1 - 0.36 11.8 5.3 4.4 8.4 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DndB PF14072.6 KII87017.1 - 0.05 12.8 0.0 0.19 10.9 0.0 1.9 2 1 0 2 2 2 0 DNA-sulfur modification-associated zf-MYND PF01753.18 KII87021.1 - 2.8e-10 40.1 4.6 4.9e-10 39.3 4.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87021.1 - 0.11 12.8 2.9 0.19 12.0 2.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding ArgJ PF01960.18 KII87022.1 - 4.2e-147 489.8 0.1 4.8e-147 489.6 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Ribosomal_L35Ae PF01247.18 KII87023.1 - 1.8e-44 149.8 0.4 2e-44 149.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KII87023.1 - 0.0036 17.5 0.1 3.1 8.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain RhoGAP PF00620.27 KII87024.1 - 1.4e-17 64.0 0.0 9.3e-17 61.3 0.0 2.3 1 1 0 1 1 1 1 RhoGAP domain DUF603 PF04645.12 KII87024.1 - 0.22 11.2 3.8 0.36 10.5 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 CtIP_N PF10482.9 KII87024.1 - 0.38 10.8 4.0 0.98 9.5 4.0 1.6 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain SlyX PF04102.12 KII87024.1 - 8.1 7.2 10.0 0.55 10.9 2.7 2.9 2 1 0 2 2 2 0 SlyX Bestrophin PF01062.21 KII87025.1 - 9.3e-37 127.0 0.3 5.3e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF515 PF04415.12 KII87025.1 - 5.1 5.4 6.4 9 4.6 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ADH_zinc_N PF00107.26 KII87026.1 - 2.2e-11 43.9 0.0 4.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII87026.1 - 1.2e-06 28.4 0.1 6.4e-05 22.8 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glycos_transf_1 PF00534.20 KII87026.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 Fe_hyd_lg_C PF02906.14 KII87026.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain zf-MYND PF01753.18 KII87027.1 - 1.6e-08 34.5 11.2 3.4e-08 33.5 11.2 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87027.1 - 6.2 7.2 12.8 2 8.8 8.8 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding adh_short PF00106.25 KII87030.1 - 9e-27 93.8 0.2 1.2e-26 93.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87030.1 - 4.2e-22 78.9 0.2 4.8e-22 78.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87030.1 - 1.8e-09 37.7 0.1 2.3e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII87030.1 - 0.0023 17.9 2.2 0.0036 17.2 2.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII87030.1 - 0.12 11.8 0.5 0.19 11.1 0.5 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 KII87031.1 - 6.2e-29 101.4 0.0 1.8e-23 83.5 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KII87031.1 - 6.3e-05 23.5 0.8 0.0044 17.6 0.1 2.9 2 2 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KII87031.1 - 0.002 17.9 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KII87031.1 - 0.11 13.1 0.1 3.3 8.3 0.0 2.9 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease Zn_clus PF00172.18 KII87032.1 - 9.2e-07 28.9 11.8 1.9e-06 27.9 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCDHK_Adom3 PF10436.9 KII87034.1 - 0.072 12.9 2.0 0.079 12.8 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase MetOD2 PF18548.1 KII87034.1 - 0.1 12.7 5.7 3.2 7.9 0.2 3.4 3 0 0 3 3 3 0 Metanogen output domain 2 YabA PF06156.13 KII87034.1 - 0.22 12.2 10.9 2.3 8.9 0.4 4.6 4 1 0 4 4 4 0 Initiation control protein YabA Flagellin_C PF00700.21 KII87034.1 - 0.25 11.7 6.6 5 7.6 0.2 3.9 3 1 1 4 4 4 0 Bacterial flagellin C-terminal helical region Jnk-SapK_ap_N PF09744.9 KII87034.1 - 0.44 10.8 28.8 0.077 13.2 2.1 3.9 3 2 2 5 5 5 0 JNK_SAPK-associated protein-1 DMPK_coil PF08826.10 KII87034.1 - 0.45 10.7 21.3 0.54 10.4 0.3 4.2 3 1 1 4 4 4 0 DMPK coiled coil domain like PhoU PF01895.19 KII87034.1 - 5.3 7.6 13.9 0.12 12.9 1.8 3.7 3 1 1 4 4 4 0 PhoU domain MPS2 PF17060.5 KII87034.1 - 5.5 6.2 6.9 1.4 8.1 1.8 2.5 3 1 0 3 3 3 0 Monopolar spindle protein 2 Fez1 PF06818.15 KII87034.1 - 7.6 6.9 28.9 0.036 14.5 2.9 4.1 3 1 0 3 3 3 0 Fez1 DUF1664 PF07889.12 KII87034.1 - 9.8 6.2 11.8 0.36 10.9 0.4 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) MAGI_u5 PF16666.5 KII87035.1 - 0.32 11.2 5.3 0.54 10.4 5.0 1.5 1 1 0 1 1 1 0 Unstructured region on MAGI zf-C2HC5 PF06221.13 KII87036.1 - 8.2e-16 57.7 4.7 1.2e-15 57.2 4.7 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type GATA PF00320.27 KII87039.1 - 2e-08 33.7 4.5 3.8e-08 32.8 4.5 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-MYND PF01753.18 KII87041.1 - 5.8e-09 35.9 13.0 1.2e-08 34.9 13.0 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87041.1 - 4.5 7.7 13.3 1.8 8.9 9.7 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-RanBP PF00641.18 KII87042.1 - 0.99 8.8 4.6 6.9 6.1 0.4 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AbrB PF05145.12 KII87045.1 - 0.27 10.1 0.0 0.4 9.6 0.0 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB VIT PF08487.10 KII87048.1 - 3.2e-32 111.0 0.3 7.9e-32 109.8 0.1 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KII87048.1 - 1.8e-20 73.4 0.0 3.5e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KII87048.1 - 3.1e-15 56.8 0.0 6.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KII87048.1 - 8.3e-10 38.4 0.0 2.6e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 KII87048.1 - 4.8e-09 36.8 0.0 1.3e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KII87048.1 - 1.2e-05 24.8 0.7 2.4e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KII87048.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus CobT_C PF11775.8 KII87048.1 - 0.046 13.4 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain zf-MYND PF01753.18 KII87049.1 - 2.7e-08 33.8 13.7 5.3e-08 32.8 13.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87049.1 - 0.68 10.3 10.3 1.3 9.4 10.3 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Mntp PF02659.15 KII87052.1 - 0.056 13.2 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative manganese efflux pump DUF3302 PF11742.8 KII87053.1 - 0.03 14.4 0.1 0.054 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) zf-CCHC_5 PF14787.6 KII87056.1 - 0.0012 18.5 0.6 0.0026 17.4 0.6 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KII87056.1 - 0.0014 18.6 1.0 0.0014 18.6 1.0 1.7 2 0 0 2 2 2 1 Zinc knuckle adh_short PF00106.25 KII87060.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase adh_short PF00106.25 KII87061.1 - 4.3e-23 81.8 0.0 5.7e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87061.1 - 5.2e-17 62.2 0.0 6.3e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87061.1 - 1.3e-07 31.8 0.0 1.6e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87061.1 - 8e-05 22.2 0.0 0.00017 21.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII87061.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII87061.1 - 0.034 13.3 0.0 0.051 12.7 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein zf-MYND PF01753.18 KII87065.1 - 3.5e-09 36.6 9.8 8.1e-09 35.4 9.8 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87065.1 - 0.39 11.1 8.0 0.67 10.3 8.0 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding adh_short PF00106.25 KII87066.1 - 6.9e-26 90.9 0.2 8.5e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87066.1 - 2.1e-20 73.3 1.2 2.6e-20 73.0 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87066.1 - 3.2e-08 33.7 0.3 4.2e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII87066.1 - 9.6e-07 28.9 0.7 1.2e-06 28.5 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII87066.1 - 0.00011 21.8 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII87066.1 - 0.00062 19.3 0.1 0.0016 17.9 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KII87066.1 - 0.0058 16.6 0.2 0.013 15.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family NmrA PF05368.13 KII87066.1 - 0.025 14.1 0.2 0.036 13.6 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Glyoxalase PF00903.25 KII87066.1 - 0.088 13.0 0.1 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Asp PF00026.23 KII87068.1 - 3.1e-33 115.5 0.0 1.7e-31 109.8 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KII87068.1 - 2.8e-05 24.7 0.3 0.00046 20.8 0.1 2.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KII87068.1 - 0.0036 17.1 0.2 0.051 13.3 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KII87068.1 - 0.024 15.2 0.1 0.17 12.4 0.0 2.3 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 KII87068.1 - 0.13 12.4 0.3 0.62 10.3 0.3 2.1 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Thiolase_N PF00108.23 KII87071.1 - 2.7e-80 269.5 3.0 2.7e-80 269.5 3.0 1.8 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KII87071.1 - 2.5e-44 149.9 0.6 5.6e-44 148.7 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KII87071.1 - 0.00051 19.7 2.4 0.0047 16.5 0.8 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KII87071.1 - 0.0042 16.9 1.1 2.1 8.2 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 KII87072.1 - 2.8e-28 98.7 0.4 3.4e-28 98.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87072.1 - 1.1e-22 80.7 0.2 1.4e-22 80.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87072.1 - 1.2e-10 41.6 0.1 1.5e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87072.1 - 1.3e-07 31.3 0.1 1.7e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII87072.1 - 2.1e-05 24.1 0.1 3.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII87072.1 - 0.016 15.1 1.7 0.026 14.4 1.7 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KII87072.1 - 0.031 14.2 0.0 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Met_10 PF02475.16 KII87072.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein NAD_binding_1 PF00175.21 KII87072.1 - 0.18 12.5 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DJ-1_PfpI PF01965.24 KII87073.1 - 1.1e-19 70.9 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 KII87074.1 - 3.6e-21 75.7 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KII87074.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 ThiJ/PfpI family-like DUF5521 PF17659.1 KII87074.1 - 0.29 8.9 0.2 0.4 8.5 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) PX PF00787.24 KII87076.1 - 2.2e-12 47.0 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF4646 PF15496.6 KII87077.1 - 0.0035 17.9 0.0 0.0069 17.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DnaJ_CXXCXGXG PF00684.19 KII87078.1 - 0.00019 21.7 5.6 0.21 12.0 1.3 2.4 2 0 0 2 2 2 2 DnaJ central domain OrfB_Zn_ribbon PF07282.11 KII87078.1 - 0.21 11.6 1.9 13 5.8 0.2 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KII87078.1 - 9.2 6.3 9.5 1.7 8.6 3.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Pkinase PF00069.25 KII87079.1 - 7.6e-05 22.2 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII87079.1 - 0.00011 22.2 0.0 0.024 14.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KII87079.1 - 0.00048 19.6 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII87079.1 - 0.046 12.5 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2587 PF10759.9 KII87084.1 - 0.032 13.7 0.3 0.036 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Antimicrobial18 PF08130.11 KII87084.1 - 0.11 12.6 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Type A lantibiotic family SLD3 PF08639.10 KII87085.1 - 2.1e-05 23.5 11.0 0.00041 19.2 3.2 3.5 1 1 2 3 3 3 3 DNA replication regulator SLD3 zf-C2H2_jaz PF12171.8 KII87086.1 - 3e-10 40.1 2.6 4.5e-10 39.6 2.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII87086.1 - 0.0037 17.6 1.5 0.006 16.9 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KII87086.1 - 0.025 14.9 0.9 0.025 14.9 0.9 1.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KII87086.1 - 0.053 14.4 0.4 0.13 13.2 0.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYND PF01753.18 KII87087.1 - 1.1e-09 38.2 13.9 1.1e-09 38.2 13.9 1.7 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KII87087.1 - 0.016 15.3 13.5 0.44 10.7 11.4 2.8 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_hydro_3_C PF01915.22 KII87088.1 - 2.7e-51 174.4 0.0 4.8e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII87088.1 - 7.4e-38 130.7 0.0 1.2e-37 130.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII87088.1 - 2.7e-22 78.7 0.0 5.2e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SPX PF03105.19 KII87088.1 - 0.54 10.1 7.0 0.81 9.5 7.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KII87088.1 - 0.68 8.7 7.4 0.91 8.3 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med3 PF11593.8 KII87088.1 - 3 6.9 19.9 4.8 6.3 19.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NTF2 PF02136.20 KII87089.1 - 0.15 12.6 0.3 0.54 10.8 0.1 2.0 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain UBA2_C PF16195.5 KII87089.1 - 0.34 11.6 8.9 0.57 10.9 1.9 3.1 2 1 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus RVT_1 PF00078.27 KII87090.1 - 1e-09 38.3 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_portal_2 PF05136.13 KII87090.1 - 0.05 12.8 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family zf-C2H2 PF00096.26 KII87091.1 - 3.3e-12 46.1 8.1 1.3e-05 25.4 1.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII87091.1 - 6.1e-08 32.9 7.5 0.00043 20.9 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII87091.1 - 6.9e-06 26.3 2.7 6.9e-06 26.3 2.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain CHORD PF04968.12 KII87091.1 - 0.017 15.8 2.4 0.61 10.8 0.2 2.1 2 0 0 2 2 2 0 CHORD FOXP-CC PF16159.5 KII87091.1 - 0.034 14.8 1.8 0.21 12.2 0.7 1.9 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KII87091.1 - 0.094 12.7 0.2 0.094 12.7 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KII87091.1 - 0.17 11.7 10.1 1.8 8.4 2.3 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KII87091.1 - 0.23 11.6 3.7 4.2 7.5 0.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KII87091.1 - 2.1 8.2 6.7 0.79 9.5 1.4 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF5107 PF17128.4 KII87093.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5107) Agglutinin_C PF18021.1 KII87094.1 - 4.6e-29 100.8 0.0 8e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Agglutinin C-terminal Lectin_C_term PF18022.1 KII87094.1 - 1.7e-24 86.2 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain RicinB_lectin_2 PF14200.6 KII87094.1 - 9e-16 58.4 7.7 2.9e-15 56.8 0.4 3.7 3 1 1 4 4 4 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KII87094.1 - 0.064 13.5 0.2 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain F-box-like PF12937.7 KII87095.1 - 0.002 18.0 0.3 0.0095 15.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like L27 PF02828.16 KII87095.1 - 0.0032 17.2 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 L27 domain F-box PF00646.33 KII87095.1 - 0.008 16.0 0.2 0.076 12.9 0.0 2.5 2 0 0 2 2 2 1 F-box domain Anoctamin PF04547.12 KII87096.1 - 1.9e-100 336.9 1.5 2.4e-100 336.5 1.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Organ_specific PF10950.8 KII87097.1 - 0.16 12.6 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Organ specific protein adh_short PF00106.25 KII87099.1 - 2.2e-22 79.5 0.0 2.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87099.1 - 1.4e-17 64.1 0.1 1.7e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87099.1 - 0.00057 19.9 0.1 0.00073 19.5 0.1 1.1 1 0 0 1 1 1 1 KR domain GATA PF00320.27 KII87100.1 - 5.9e-30 102.6 14.1 7.9e-16 57.4 3.4 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KII87100.1 - 0.00012 21.6 6.1 0.064 12.8 0.3 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KII87100.1 - 0.0035 17.4 0.8 0.41 10.7 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 KII87100.1 - 0.0081 16.3 4.1 1.7 8.8 0.3 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KII87100.1 - 0.015 15.4 1.3 3.9 7.7 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KII87100.1 - 0.2 11.6 3.8 7.9 6.4 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FAM60A PF15396.6 KII87100.1 - 9.7 6.1 10.3 39 4.1 7.6 2.5 2 1 0 2 2 2 0 Protein Family FAM60A Ribosomal_L37e PF01907.19 KII87101.1 - 4.3e-26 90.8 12.5 9.4e-26 89.7 12.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KII87101.1 - 0.011 15.8 1.7 0.022 14.8 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon SelR PF01641.18 KII87101.1 - 0.03 14.4 1.1 0.043 13.9 0.7 1.5 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 KII87101.1 - 0.11 12.6 0.8 0.17 11.9 0.8 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2427 PF10348.9 KII87102.1 - 2 8.3 7.0 0.13 12.0 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) VPS9 PF02204.18 KII87103.1 - 1.6e-15 57.2 0.0 3.7e-14 52.8 0.0 2.3 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KII87103.1 - 0.0016 18.7 0.0 0.0052 17.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5601) RXT2_N PF08595.11 KII87103.1 - 2.8 8.0 6.8 0.25 11.4 2.0 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 KII87103.1 - 5.7 6.6 5.1 17 5.1 2.9 2.2 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 KII87103.1 - 5.7 6.2 8.8 9.4 5.5 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein adh_short PF00106.25 KII87104.1 - 1.5e-23 83.3 0.0 2.5e-23 82.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87104.1 - 2.3e-19 69.9 0.0 3e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87104.1 - 0.00045 20.2 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Pox_TAA1 PF03295.14 KII87104.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal AIRC PF00731.20 KII87104.1 - 0.056 13.0 0.4 0.096 12.3 0.4 1.3 1 0 0 1 1 1 0 AIR carboxylase adh_short PF00106.25 KII87105.1 - 8.3e-27 93.9 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87105.1 - 4.6e-21 75.5 0.0 5.5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KII87105.1 - 1.7e-08 34.3 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII87105.1 - 1.3e-05 25.2 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KII87105.1 - 0.00026 20.5 0.0 0.00055 19.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII87105.1 - 0.0025 17.7 0.4 0.0036 17.2 0.5 1.3 1 1 0 1 1 1 1 NAD(P)H-binding AIRC PF00731.20 KII87105.1 - 0.2 11.2 1.2 0.57 9.8 0.9 1.8 1 1 1 2 2 2 0 AIR carboxylase Kinesin PF00225.23 KII87106.1 - 2e-75 253.8 0.0 4e-75 252.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII87106.1 - 1.3e-59 200.4 0.2 3.7e-59 199.0 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Ham1p_like PF01725.16 KII87106.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Ham1 family ATPase_2 PF01637.18 KII87106.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Filament PF00038.21 KII87106.1 - 0.27 10.8 18.7 0.75 9.3 18.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein YabA PF06156.13 KII87106.1 - 0.37 11.5 12.7 28 5.4 0.0 4.3 4 0 0 4 4 4 0 Initiation control protein YabA Spc29 PF17082.5 KII87106.1 - 0.45 10.3 6.5 4.8 7.0 0.1 2.6 1 1 1 2 2 2 0 Spindle Pole Component 29 BRE1 PF08647.11 KII87106.1 - 2.5 8.2 15.6 0.48 10.5 1.2 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 KII87106.1 - 2.6 6.5 13.2 4.7 5.6 13.2 1.4 1 0 0 1 1 1 0 Macoilin family DUF4472 PF14739.6 KII87106.1 - 4.6 8.0 16.7 1.5 9.5 2.4 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 KII87106.1 - 5.4 7.5 23.1 2.4 8.7 8.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 KII87106.1 - 6.7 6.5 28.7 0.068 13.0 12.4 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 KII87106.1 - 7.8 7.2 22.8 0.44 11.2 10.9 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KxDL PF10241.9 KII87106.1 - 9.4 6.6 11.6 2.3 8.5 0.4 3.5 1 1 1 2 2 2 0 Uncharacterized conserved protein Maf PF02545.14 KII87107.1 - 0.15 11.9 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Maf-like protein DUF5542 PF17696.1 KII87109.1 - 0.17 12.1 0.6 14 5.9 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5542) Carla_C4 PF01623.17 KII87109.1 - 1.2 9.2 8.8 0.061 13.3 2.7 2.0 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein Kinesin PF00225.23 KII87111.1 - 5.8e-67 226.0 0.3 5.8e-67 226.0 0.3 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KII87111.1 - 2.4e-54 183.3 0.0 1e-53 181.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Ham1p_like PF01725.16 KII87111.1 - 0.15 11.9 1.0 0.3 11.0 0.0 2.0 2 1 0 2 2 2 0 Ham1 family Filament PF00038.21 KII87111.1 - 0.32 10.6 22.8 1 8.9 22.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein ATG16 PF08614.11 KII87111.1 - 0.55 10.4 35.6 2.3 8.4 12.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 KII87111.1 - 0.73 8.6 28.0 1.1 8.0 28.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 KII87111.1 - 1.3 9.8 19.5 0.93 10.3 2.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Macoilin PF09726.9 KII87111.1 - 2.4 6.6 23.5 0.48 8.9 6.6 2.2 1 1 1 2 2 2 0 Macoilin family PRKG1_interact PF15898.5 KII87111.1 - 5.6 7.9 23.8 0.45 11.4 3.3 3.7 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 KII87111.1 - 7.9 5.0 12.1 15 4.1 12.1 1.4 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 KII87114.1 - 0.78 9.7 9.7 0.77 9.7 2.9 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Kinesin PF00225.23 KII87115.1 - 2.6e-101 338.9 0.0 4.7e-101 338.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII87115.1 - 5.7e-60 201.6 0.1 1.9e-59 199.9 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Filament PF00038.21 KII87115.1 - 0.047 13.3 19.2 0.12 11.9 19.2 1.6 1 1 0 1 1 1 0 Intermediate filament protein Ham1p_like PF01725.16 KII87115.1 - 0.069 13.1 0.6 0.19 11.6 0.0 2.0 2 1 0 2 2 2 0 Ham1 family WEMBL PF05701.11 KII87115.1 - 0.77 8.4 21.5 1.5 7.4 21.5 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF4472 PF14739.6 KII87115.1 - 0.97 10.2 17.9 0.14 12.9 2.5 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4472) Bap31_Bap29_C PF18035.1 KII87115.1 - 1.7 8.7 5.4 25 5.0 0.8 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Macoilin PF09726.9 KII87115.1 - 2.7 6.4 14.3 5.4 5.5 14.3 1.4 1 0 0 1 1 1 0 Macoilin family CALCOCO1 PF07888.11 KII87115.1 - 3 6.6 26.8 4.3 6.1 26.8 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HIP1_clath_bdg PF16515.5 KII87115.1 - 6.7 7.4 25.6 0.61 10.7 12.3 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 KII87115.1 - 8.5 6.5 17.7 2.8 8.1 2.4 2.8 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Sec8_exocyst PF04048.14 KII87115.1 - 9.9 6.0 9.5 0.45 10.4 0.8 3.0 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 KII87115.1 - 10 6.2 7.9 4.8 7.2 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) adh_short PF00106.25 KII87116.1 - 6.7e-22 77.9 0.3 8.7e-22 77.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87116.1 - 3.4e-18 66.0 0.1 4.2e-18 65.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87116.1 - 0.0066 16.4 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KII87118.1 - 5.9e-24 84.6 0.4 8e-24 84.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87118.1 - 5e-19 68.8 1.0 6.3e-19 68.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87118.1 - 0.00041 20.3 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII87118.1 - 0.0024 17.8 1.3 0.0032 17.4 1.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KII87119.1 - 5.9e-26 91.1 0.5 8e-26 90.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87119.1 - 7.7e-20 71.4 0.4 9.5e-20 71.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KII87119.1 - 1.5e-05 25.0 0.4 2e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KII87119.1 - 5.7e-05 23.1 0.1 7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87119.1 - 0.034 13.6 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_1 PF00175.21 KII87119.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain adh_short PF00106.25 KII87120.1 - 9.4e-27 93.7 0.3 1.3e-26 93.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87120.1 - 4.2e-20 72.3 1.3 5.1e-20 72.0 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87120.1 - 0.00014 21.8 0.1 0.00018 21.5 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII87120.1 - 0.012 15.5 3.4 0.017 15.0 3.4 1.5 1 1 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KII87121.1 - 5.6e-21 74.9 0.1 1.4e-09 37.7 0.0 3.2 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KII87121.1 - 3.4e-15 56.2 1.0 1.5e-08 34.5 0.1 3.0 1 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87121.1 - 0.051 13.5 0.4 0.28 11.1 0.4 2.0 1 1 0 1 1 1 0 KR domain Opi1 PF08618.10 KII87122.1 - 9.2e-75 252.5 30.4 4.6e-42 144.7 1.2 4.3 3 2 0 3 3 3 2 Transcription factor Opi1 adh_short PF00106.25 KII87123.1 - 1.6e-23 83.2 0.3 2.1e-23 82.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87123.1 - 1.4e-18 67.3 0.9 1.7e-18 67.0 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87123.1 - 1.6e-06 28.2 0.3 2.2e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87123.1 - 8e-05 22.2 0.1 0.00012 21.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII87123.1 - 0.0085 16.0 1.3 0.012 15.5 1.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII87123.1 - 0.014 14.8 0.2 0.055 12.9 0.2 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase F-box PF00646.33 KII87124.1 - 0.0003 20.6 0.1 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII87124.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like UQ_con PF00179.26 KII87125.1 - 1.7e-17 63.4 0.0 1.8e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII87125.1 - 0.036 14.4 0.0 0.037 14.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain VHS PF00790.19 KII87126.1 - 5.4e-30 104.1 0.1 9.7e-30 103.3 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KII87126.1 - 4.1e-14 51.9 0.0 7.3e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII87126.1 - 4.5e-14 51.9 0.1 7.8e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII87126.1 - 5.3e-14 51.8 0.1 1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KII87126.1 - 1.6e-11 44.3 1.6 4.1e-11 43.0 1.6 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KII87126.1 - 0.012 15.4 1.9 0.012 15.4 1.9 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF4254 PF14063.6 KII87126.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Hrs_helical PF12210.8 KII87126.1 - 0.23 12.0 1.0 0.56 10.8 1.0 1.6 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate F-box-like PF12937.7 KII87127.1 - 1e-07 31.7 4.0 1.7e-06 27.8 0.2 3.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII87127.1 - 0.047 13.6 0.9 0.15 12.0 0.0 2.3 2 1 0 2 2 2 0 F-box domain FKS1_dom1 PF14288.6 KII87127.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 UQ_con PF00179.26 KII87129.1 - 9.3e-18 64.2 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.17 KII87130.1 - 4.8e-41 140.5 0.0 5.5e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 KII87130.1 - 0.00071 19.1 0.0 0.0019 17.7 0.0 1.6 2 1 0 2 2 2 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 KII87130.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 KII87130.1 - 0.089 13.0 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pro_isomerase PF00160.21 KII87131.1 - 2.2e-40 138.5 0.0 5.1e-40 137.3 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KII87131.1 - 0.00039 20.9 0.1 0.00039 20.9 0.1 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) HAUS6_N PF14661.6 KII87132.1 - 2.4e-11 43.7 0.2 4.6e-10 39.5 0.2 2.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus FAD_binding_3 PF01494.19 KII87133.1 - 7.5e-21 74.8 0.1 1.7e-20 73.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KII87133.1 - 2.6e-05 23.5 0.3 3.6e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KII87133.1 - 7.1e-05 23.0 1.6 0.00019 21.6 1.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII87133.1 - 0.0027 17.0 1.8 0.0044 16.3 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KII87133.1 - 0.003 16.5 0.2 0.0059 15.5 0.2 1.5 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 KII87133.1 - 0.037 13.1 0.4 0.046 12.8 0.4 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KII87133.1 - 0.055 12.2 3.4 0.076 11.7 3.4 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KII87133.1 - 0.07 13.7 2.6 0.15 12.6 2.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII87133.1 - 0.087 12.2 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 KII87133.1 - 0.17 11.5 6.3 0.18 11.3 4.3 1.9 1 1 2 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII87134.1 - 8.4e-23 81.2 0.0 1.7e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KII87134.1 - 1.2e-06 27.7 0.1 2.8e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KII87134.1 - 2.6e-05 24.3 2.3 8e-05 22.8 2.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII87134.1 - 0.0035 16.6 2.1 0.0058 15.9 2.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII87134.1 - 0.006 15.7 3.2 0.0094 15.1 3.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KII87134.1 - 0.014 14.1 0.7 0.023 13.4 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KII87134.1 - 0.017 15.7 1.2 0.017 15.7 1.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII87134.1 - 0.28 10.2 1.7 0.4 9.7 1.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KII87134.1 - 0.64 9.3 2.1 0.73 9.1 1.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 KII87134.1 - 0.9 9.1 7.4 0.69 9.4 5.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Exo_endo_phos PF03372.23 KII87135.1 - 1.3e-12 47.7 0.2 3.4e-12 46.4 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KII87135.1 - 7.8e-07 29.1 3.6 1e-05 25.5 0.7 2.4 2 0 0 2 2 2 1 GRF zinc finger SWIRM-assoc_2 PF16496.5 KII87135.1 - 1.3 7.8 5.6 16 4.2 5.4 2.0 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Med3 PF11593.8 KII87135.1 - 6.2 5.9 14.8 8.6 5.4 14.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.12 KII87135.1 - 7.5 5.1 11.8 11 4.5 11.8 1.3 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 KII87135.1 - 7.9 5.0 7.6 10 4.7 7.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_Tyr PF07714.17 KII87137.1 - 7.9e-25 87.6 0.0 8.8e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII87137.1 - 2.1e-20 73.2 0.0 2.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KII87137.1 - 0.041 12.7 0.9 0.053 12.3 0.9 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KII87137.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Myb_DNA-binding PF00249.31 KII87139.1 - 0.00058 20.0 0.1 0.066 13.4 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Pkinase PF00069.25 KII87140.1 - 1.1e-12 47.9 0.0 8.5e-10 38.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII87140.1 - 2.5e-07 30.3 0.1 3.7e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KII87141.1 - 6.2e-31 107.6 0.0 6.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII87141.1 - 5e-23 81.8 0.0 6.6e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII87141.1 - 0.00025 20.5 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII87141.1 - 0.0073 16.3 0.1 0.019 14.9 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII87141.1 - 0.0089 14.8 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KII87141.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HSP20 PF00011.21 KII87142.1 - 8.5e-13 48.3 0.0 1e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII87142.1 - 8.3e-07 28.5 0.1 3.2e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA F-box-like PF12937.7 KII87147.1 - 0.00027 20.8 1.9 0.00048 20.0 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII87147.1 - 0.0015 18.4 0.1 0.0048 16.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ribonuc_red_sm PF00268.21 KII87149.1 - 7.4e-104 347.1 0.0 8.7e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Methyltransf_23 PF13489.6 KII87150.1 - 1.1e-18 67.7 0.0 1.6e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII87150.1 - 2.1e-13 50.8 0.0 6.1e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87150.1 - 7.9e-12 45.7 0.0 1.6e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII87150.1 - 1.6e-09 37.7 0.0 2.9e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII87150.1 - 1.6e-06 28.8 0.0 5.3e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KII87150.1 - 4e-05 22.4 0.0 0.0038 15.8 0.0 2.0 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KII87150.1 - 0.00013 21.3 0.0 0.00058 19.2 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 KII87150.1 - 0.00027 20.9 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KII87150.1 - 0.00075 18.9 0.0 0.006 15.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KII87150.1 - 0.0018 17.8 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KII87150.1 - 0.004 16.7 0.0 0.0094 15.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.12 KII87150.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KII87150.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KII87150.1 - 0.033 13.5 0.0 0.084 12.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase F-box PF00646.33 KII87153.1 - 0.062 13.2 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 F-box domain BHD_1 PF10403.9 KII87153.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Skp1 PF01466.19 KII87155.1 - 9.1e-22 76.9 0.1 1.6e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KII87155.1 - 2.9e-17 62.6 0.2 5.6e-17 61.7 0.2 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain O-FucT PF10250.9 KII87157.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase XPC-binding PF09280.11 KII87158.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain TetR_C_30 PF17939.1 KII87158.1 - 0.14 12.4 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RhoGEF PF00621.20 KII87159.1 - 2.5e-36 125.6 0.0 3.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 KII87159.1 - 2.5e-16 59.6 13.3 4.1e-16 58.9 13.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger Cas_Csy3 PF09615.10 KII87159.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) PH PF00169.29 KII87159.1 - 0.067 13.7 0.1 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 PH domain FYVE_2 PF02318.16 KII87159.1 - 3.1 8.0 8.6 6.1 7.1 8.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger F-box-like PF12937.7 KII87160.1 - 7e-08 32.2 0.3 8.5e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 KII87160.1 - 0.19 12.5 0.3 4.8 8.0 0.3 3.3 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 KII87161.1 - 3.2e-62 205.0 29.6 9.6e-10 38.9 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87161.1 - 9.4e-22 77.1 2.1 0.00019 21.6 0.0 5.8 2 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KII87161.1 - 1.5e-10 41.4 0.1 2.7e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KII87161.1 - 0.00012 21.0 7.0 0.47 9.0 0.2 4.5 3 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KII87161.1 - 0.00073 18.6 0.0 0.39 9.6 0.0 3.7 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KII87161.1 - 0.0059 15.4 0.4 3.7 6.2 0.0 3.3 4 0 0 4 4 4 2 Nup133 N terminal like PD40 PF07676.12 KII87161.1 - 0.068 13.1 0.2 4.3 7.4 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KII87161.1 - 0.12 10.6 0.0 2.8 6.2 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KII87161.1 - 0.17 11.1 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Pirin PF02678.16 KII87162.1 - 7.8e-27 93.4 0.7 1.4e-26 92.6 0.7 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KII87162.1 - 6.1e-10 38.7 0.9 7.4e-07 28.8 0.4 2.2 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KII87162.1 - 5.6e-06 26.4 0.0 9.4e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 KII87162.1 - 0.095 12.4 0.7 0.8 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF2263 PF10021.9 KII87163.1 - 2.9e-14 53.7 0.0 4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KII87163.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Macro domain SAICAR_synt PF01259.18 KII87164.1 - 1.6e-95 319.5 0.0 5.4e-95 317.8 0.0 1.7 1 1 0 1 1 1 1 SAICAR synthetase RNA_pol_Rpb2_3 PF04565.16 KII87170.1 - 0.25 11.6 3.4 0.18 12.0 1.1 2.0 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Tmemb_170 PF10190.9 KII87172.1 - 5.8e-10 39.5 7.1 9.9e-08 32.3 3.0 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 WD40 PF00400.32 KII87173.1 - 1.1e-57 190.6 26.2 1.3e-09 38.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87173.1 - 1.5e-21 76.4 4.5 0.00018 21.7 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII87173.1 - 5.1e-10 39.6 0.4 0.00017 21.6 0.0 3.4 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KII87173.1 - 5.5e-08 31.9 11.7 0.0053 15.5 0.1 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KII87173.1 - 6.2e-06 25.4 5.5 0.012 14.5 0.0 4.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KII87173.1 - 7.9e-06 25.4 0.2 0.0033 16.8 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain CDtoxinA PF03498.14 KII87173.1 - 0.0019 17.8 1.2 0.0042 16.7 0.5 1.9 2 1 0 2 2 2 1 Cytolethal distending toxin A/C domain Cytochrom_D1 PF02239.16 KII87173.1 - 0.0097 14.5 0.3 0.39 9.2 0.1 2.5 2 1 1 3 3 3 2 Cytochrome D1 heme domain Utp8 PF10395.9 KII87173.1 - 0.028 12.9 0.1 0.1 11.1 0.0 1.8 2 0 0 2 2 2 0 Utp8 family Pectate_lyase22 PF14583.6 KII87173.1 - 0.028 13.1 0.0 0.075 11.7 0.0 1.6 2 0 0 2 2 2 0 Oligogalacturonate lyase Arylsulfotran_2 PF14269.6 KII87173.1 - 0.039 13.3 0.2 0.076 12.4 0.2 1.4 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Kelch_6 PF13964.6 KII87173.1 - 0.086 13.2 1.5 3.6 8.0 0.1 3.4 4 0 0 4 4 4 0 Kelch motif IKI3 PF04762.12 KII87173.1 - 0.12 10.3 0.2 2.7 5.9 0.2 2.6 2 1 0 2 2 2 0 IKI3 family DUF2721 PF11026.8 KII87174.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) NADH-u_ox-rdase PF10785.9 KII87175.1 - 3.3e-31 107.8 0.1 6.5e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KII87175.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DIOX_N PF14226.6 KII87176.1 - 6.7e-16 59.1 0.0 1.1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII87176.1 - 2e-13 50.7 0.0 3.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.18 KII87177.1 - 1e-48 165.9 0.0 1.5e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 KII87177.1 - 6.8e-06 26.5 0.7 0.00058 20.3 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KII87177.1 - 0.00018 20.8 2.1 0.0012 18.2 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KII87177.1 - 0.00033 20.4 4.1 0.0016 18.2 0.7 2.8 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 KII87177.1 - 0.001 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_8 PF13833.6 KII87177.1 - 0.022 14.6 1.9 4.3 7.3 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KII87177.1 - 0.051 13.1 0.1 0.16 11.5 0.1 1.9 1 0 0 1 1 1 0 EF hand Pes-10 PF07149.11 KII87177.1 - 0.97 8.4 6.4 1.7 7.6 6.4 1.3 1 0 0 1 1 1 0 Pes-10 Na_H_Exchanger PF00999.21 KII87178.1 - 3.4e-30 105.1 30.5 3.2e-29 101.9 30.5 1.9 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Nucleos_tra2_N PF01773.20 KII87178.1 - 0.26 11.9 10.2 0.71 10.5 2.9 3.1 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Vps36-NZF-N PF16988.5 KII87179.1 - 0.00051 19.4 12.5 0.056 12.9 1.6 2.7 2 0 0 2 2 2 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 KII87179.1 - 0.00073 18.8 20.4 0.009 15.3 6.6 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 KII87179.1 - 0.0091 16.0 1.0 4.2 7.5 0.3 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Prok-RING_2 PF14445.6 KII87179.1 - 0.093 12.9 5.4 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Pkinase PF00069.25 KII87180.1 - 1.6e-72 244.1 0.0 1.9e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87180.1 - 6.9e-32 110.7 0.0 1.3e-31 109.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KII87180.1 - 0.012 15.6 0.1 0.032 14.2 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KII87180.1 - 0.017 14.5 0.1 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KII87180.1 - 0.019 13.9 0.1 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Abhydrolase_1 PF00561.20 KII87181.1 - 2.5e-19 69.9 0.0 3.3e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII87181.1 - 5.3e-13 50.1 0.2 6.5e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII87181.1 - 2.5e-09 36.8 0.0 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 KII87181.1 - 4.8e-05 23.6 0.0 7.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KII87182.1 - 3.6e-20 72.7 0.0 9e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII87182.1 - 2.7e-13 51.0 1.1 3.4e-13 50.7 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII87182.1 - 1e-12 47.8 0.1 5.4e-11 42.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KII87182.1 - 0.0074 16.4 0.1 0.018 15.1 0.0 1.7 2 1 0 2 2 2 1 Thioesterase domain DUF1658 PF07871.11 KII87182.1 - 0.042 13.8 0.2 0.097 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) DnaJ PF00226.31 KII87183.1 - 5.1e-16 58.5 0.3 8.9e-16 57.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain AIF-MLS PF14962.6 KII87183.1 - 0.024 14.6 1.1 0.042 13.8 1.1 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence MSP1b PF03429.13 KII87183.1 - 0.082 11.0 1.8 0.1 10.7 1.8 1.0 1 0 0 1 1 1 0 Major surface protein 1B DUF1664 PF07889.12 KII87183.1 - 0.097 12.7 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SusD_RagB PF07980.11 KII87183.1 - 0.38 10.3 4.7 0.47 10.0 4.7 1.2 1 0 0 1 1 1 0 SusD family Arg_decarbox_C PF17944.1 KII87183.1 - 0.46 11.1 0.1 0.46 11.1 0.1 2.3 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension FUSC PF04632.12 KII87183.1 - 1.1 7.8 12.1 1.2 7.6 12.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family OHCU_decarbox PF09349.10 KII87184.1 - 1.2e-32 113.6 0.0 1.4e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase GFO_IDH_MocA PF01408.22 KII87185.1 - 5e-20 72.5 0.1 7.6e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KII87185.1 - 0.096 13.3 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_deac_2 PF04748.13 KII87185.1 - 0.13 11.4 0.2 8.9 5.4 0.0 2.3 1 1 1 2 2 2 0 Divergent polysaccharide deacetylase DUF3328 PF11807.8 KII87186.1 - 1.2e-14 54.7 0.2 1.5e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KII87188.1 - 2.2e-16 60.3 7.4 1.4e-15 57.7 7.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3818 PF12825.7 KII87188.1 - 0.056 12.5 0.2 0.088 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF4937 PF16291.5 KII87188.1 - 0.11 12.7 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4937 zf-CCCH PF00642.24 KII87191.1 - 2.8e-10 39.9 27.6 6.8e-05 22.7 5.4 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII87191.1 - 6.1e-09 35.5 28.4 9.6e-05 22.1 6.0 3.7 3 0 0 3 3 3 3 CCCH-type zinc finger zf-C3HC4 PF00097.25 KII87191.1 - 1.2e-08 34.7 7.5 3.7e-08 33.1 7.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII87191.1 - 2.3e-08 33.8 6.3 7.1e-08 32.2 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 KII87191.1 - 3.8e-08 34.0 14.2 4.6e-07 30.5 2.5 3.3 2 1 1 3 3 3 2 Torus domain zf-RING_2 PF13639.6 KII87191.1 - 5.2e-08 33.1 7.9 5.2e-08 33.1 7.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf_CCCH_4 PF18345.1 KII87191.1 - 4.3e-06 26.6 9.7 4.3e-06 26.6 9.7 4.6 4 1 0 4 4 4 2 Zinc finger domain zf-rbx1 PF12678.7 KII87191.1 - 1.4e-05 25.3 3.1 5.7e-05 23.3 3.1 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KII87191.1 - 0.0001 22.2 5.7 0.00011 22.1 3.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII87191.1 - 0.00022 21.0 4.4 0.00022 21.0 4.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII87191.1 - 0.00042 20.2 7.0 0.0021 18.0 7.2 2.2 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII87191.1 - 0.0023 17.8 5.9 0.0023 17.8 5.9 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-CCCH_2 PF14608.6 KII87191.1 - 0.0047 17.3 30.8 0.16 12.5 3.2 3.7 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 KII87191.1 - 0.043 14.0 8.7 0.19 11.9 8.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KII87191.1 - 0.41 10.5 6.5 1.5 8.7 6.5 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KII87191.1 - 1.9 8.3 8.8 10 6.0 8.8 2.2 1 1 0 1 1 1 0 RING-like zinc finger SAGA-Tad1 PF12767.7 KII87194.1 - 6.7e-24 84.9 0.0 1.2e-23 84.1 0.0 1.4 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KII87194.1 - 0.058 13.1 0.1 0.075 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.13 KII87195.1 - 6.3e-26 90.1 0.0 9.4e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_60s PF00428.19 KII87195.1 - 0.0048 17.4 5.4 0.22 12.1 0.0 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Bromo_TP PF07524.13 KII87195.1 - 0.011 15.8 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated WD40 PF00400.32 KII87196.1 - 7.2e-10 39.3 4.0 0.21 12.5 0.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87196.1 - 4.7e-09 36.4 0.1 0.019 15.2 0.0 4.7 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF1192 PF06698.11 KII87196.1 - 0.0017 18.3 0.3 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Nucleoporin_N PF08801.11 KII87196.1 - 0.014 14.1 0.1 0.15 10.7 0.1 2.4 2 0 0 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 KII87196.1 - 0.11 11.8 0.0 2 7.7 0.0 2.2 2 1 0 2 2 2 0 WD40-like domain Utp8 PF10395.9 KII87196.1 - 0.12 10.8 0.0 0.33 9.4 0.0 1.7 1 1 0 1 1 1 0 Utp8 family DnaJ PF00226.31 KII87197.1 - 6.7e-20 71.0 0.1 1.4e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 KII87198.1 - 3.4e-13 49.2 1.0 1.8e-12 46.9 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII87198.1 - 4.3e-05 23.5 13.4 0.00011 22.2 13.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCA7 PF08313.12 KII87199.1 - 9.8e-28 95.9 0.3 9.8e-28 95.9 0.3 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf_UBZ PF18439.1 KII87199.1 - 0.012 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_3_C PF01915.22 KII87199.1 - 0.033 14.2 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain BAF1_ABF1 PF04684.13 KII87199.1 - 0.53 9.3 4.5 0.6 9.1 4.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3138 PF11336.8 KII87199.1 - 0.96 8.0 12.4 1.5 7.4 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) F-box-like PF12937.7 KII87201.1 - 2.6e-06 27.2 0.1 6.5e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like RNA_pol_Rpc4 PF05132.14 KII87202.1 - 4.8e-35 121.2 0.2 4.8e-35 121.2 0.2 3.0 3 1 0 3 3 3 1 RNA polymerase III RPC4 PAT1 PF09770.9 KII87204.1 - 5.2e-106 355.9 69.8 7.1e-104 348.8 69.8 2.9 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.27 KII87205.1 - 3.4e-66 219.2 1.8 3.1e-23 81.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Alg14 PF08660.11 KII87205.1 - 0.027 14.4 0.2 0.43 10.5 0.1 2.0 1 1 1 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like KduI PF04962.12 KII87205.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 KduI/IolB family Pribosyltran PF00156.27 KII87206.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DNA_Packaging_2 PF11123.8 KII87206.1 - 0.0021 18.2 0.0 0.89 9.8 0.0 2.3 2 0 0 2 2 2 2 DNA packaging protein hDGE_amylase PF14701.6 KII87207.1 - 9.1e-160 532.5 0.0 1.2e-159 532.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KII87207.1 - 1.4e-119 399.5 0.0 1.8e-119 399.1 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KII87207.1 - 4.2e-82 275.6 0.0 5.9e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KII87207.1 - 2e-21 75.9 0.0 4.5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Amidase PF01425.21 KII87208.1 - 3.6e-101 339.4 0.0 6e-101 338.6 0.0 1.3 1 1 0 1 1 1 1 Amidase RRM_1 PF00076.22 KII87209.1 - 6.3e-28 96.4 1.5 3.3e-12 46.0 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII87209.1 - 9.5e-06 25.6 0.0 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KII87209.1 - 0.008 16.0 0.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_9 PF18444.1 KII87209.1 - 0.024 14.5 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif Fis1_TPR_C PF14853.6 KII87210.1 - 8.3e-23 80.2 0.1 1.4e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KII87210.1 - 1e-15 57.1 0.0 1.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KII87210.1 - 0.00025 20.9 0.1 0.00058 19.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII87210.1 - 0.0093 16.5 0.1 0.02 15.4 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII87210.1 - 0.011 15.6 0.3 0.02 14.7 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII87210.1 - 0.032 14.9 0.0 0.12 13.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Histone PF00125.24 KII87211.1 - 1e-17 64.7 0.0 1.2e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KII87211.1 - 2e-17 62.6 1.7 4.2e-17 61.6 1.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KII87211.1 - 6.1e-06 26.4 0.0 8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M50B PF13398.6 KII87212.1 - 1.2e-45 155.7 16.3 1.4e-45 155.4 16.3 1.0 1 0 0 1 1 1 1 Peptidase M50B-like DUF1317 PF07026.11 KII87212.1 - 0.021 14.7 0.5 0.036 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) MFS_1 PF07690.16 KII87214.1 - 4.9e-19 68.5 28.1 4.9e-19 68.5 28.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_57 PF18679.1 KII87214.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 ThcOx helix turn helix domain F-box-like PF12937.7 KII87215.1 - 4.4e-05 23.3 0.9 0.00016 21.5 0.2 2.5 2 0 0 2 2 2 1 F-box-like KDZ PF18758.1 KII87217.1 - 2.5e-49 167.9 0.3 6.8e-49 166.5 0.0 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII87217.1 - 8.7e-43 144.9 0.1 2e-42 143.7 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII87217.1 - 0.00099 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 KII87219.1 - 9.3e-08 32.3 0.1 1.5e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Cuticle_3 PF11018.8 KII87219.1 - 0.45 10.7 20.5 0.74 10.0 20.5 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 adh_short_C2 PF13561.6 KII87221.1 - 9.9e-38 130.0 0.0 1.3e-37 129.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII87221.1 - 2.4e-26 92.4 0.0 2.9e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII87221.1 - 5.2e-05 23.2 0.0 8.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87221.1 - 0.031 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_nitro PF00148.19 KII87221.1 - 0.045 12.5 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 2-Hacid_dh_C PF02826.19 KII87221.1 - 0.065 12.6 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF5612 PF18462.1 KII87221.1 - 0.15 11.9 0.3 0.36 10.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) DEAD PF00270.29 KII87223.1 - 1.4e-46 158.5 0.0 2.3e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII87223.1 - 1.8e-29 102.3 0.0 7.5e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII87223.1 - 0.0089 16.0 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KII87223.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-Sec23_Sec24 PF04810.15 KII87224.1 - 0.064 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Arginosuc_synth PF00764.19 KII87225.1 - 1.5e-153 511.7 0.0 1.8e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KII87225.1 - 0.00057 19.4 0.0 0.00085 18.9 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KII87225.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase F-box PF00646.33 KII87227.1 - 0.00011 22.0 0.9 0.00021 21.1 0.9 1.5 1 0 0 1 1 1 1 F-box domain Hira PF07569.11 KII87227.1 - 0.19 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split F-box-like PF12937.7 KII87227.1 - 0.34 10.8 3.8 0.23 11.4 1.6 1.9 2 0 0 2 2 2 0 F-box-like zf-RING_2 PF13639.6 KII87228.1 - 2.3e-08 34.2 6.0 7.5e-08 32.6 2.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII87228.1 - 2.2e-06 27.4 2.7 2.2e-06 27.4 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KII87228.1 - 3.1e-06 27.4 8.7 1.3e-05 25.4 8.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KII87228.1 - 4.9e-06 26.3 1.7 1.5e-05 24.8 1.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KII87228.1 - 1.9e-05 24.3 4.2 0.0067 16.2 0.6 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 KII87228.1 - 0.0002 21.3 1.3 0.0003 20.7 0.4 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KII87228.1 - 0.00051 19.8 1.8 0.00051 19.8 1.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII87228.1 - 0.00064 19.5 1.9 0.0019 18.0 1.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KII87228.1 - 0.0014 18.7 1.0 0.0037 17.3 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KII87228.1 - 0.0048 16.9 3.2 0.036 14.1 3.2 2.3 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KII87228.1 - 0.013 15.1 1.2 0.032 13.8 1.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KII87228.1 - 0.029 14.2 0.4 0.068 13.0 0.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FAD_binding_7 PF03441.14 KII87228.1 - 0.11 12.0 0.1 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase zf-P11 PF03854.14 KII87228.1 - 0.15 11.7 3.2 0.34 10.6 3.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3H2C3 PF17122.5 KII87228.1 - 0.23 11.5 2.6 0.56 10.3 2.6 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 KII87228.1 - 3 8.1 8.0 0.17 12.1 2.2 1.8 2 0 0 2 2 2 0 RING-variant domain FAP PF07174.11 KII87228.1 - 5.9 6.2 25.9 11 5.4 25.9 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-C3HC4_2 PF13923.6 KII87229.1 - 6.8e-07 29.0 2.1 6.8e-07 29.0 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII87229.1 - 7.9e-07 29.0 3.1 7.9e-07 29.0 3.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII87229.1 - 1.3e-06 28.1 0.7 2.7e-06 27.2 0.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII87229.1 - 3.8e-06 27.1 7.1 2e-05 24.8 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII87229.1 - 5.7e-06 26.1 9.2 6.2e-05 22.8 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII87229.1 - 1.1e-05 25.3 4.7 1.8e-05 24.6 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KII87229.1 - 2.9e-05 24.1 2.4 2.9e-05 24.1 2.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KII87229.1 - 0.00049 19.9 7.6 0.01 15.7 7.6 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KII87229.1 - 0.0034 17.2 0.4 0.0069 16.2 0.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein AIP3 PF03915.13 KII87229.1 - 0.012 14.7 4.0 0.016 14.3 4.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 zf-RING_10 PF16685.5 KII87229.1 - 0.016 15.4 1.8 0.033 14.3 1.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Fib_alpha PF08702.10 KII87229.1 - 0.017 15.3 5.2 0.029 14.6 5.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 KII87229.1 - 0.024 14.7 8.0 0.037 14.1 8.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Zn_ribbon_17 PF17120.5 KII87229.1 - 0.029 14.0 0.3 0.029 14.0 0.3 1.6 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type DUF1732 PF08340.11 KII87229.1 - 0.048 13.6 4.7 0.079 13.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) FAM76 PF16046.5 KII87229.1 - 0.054 12.9 17.0 0.1 11.9 17.0 1.6 1 1 0 1 1 1 0 FAM76 protein AKNA PF12443.8 KII87229.1 - 0.083 13.5 3.4 0.2 12.3 3.4 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor Sec8_exocyst PF04048.14 KII87229.1 - 0.11 12.3 3.8 0.21 11.5 3.8 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Fez1 PF06818.15 KII87229.1 - 0.14 12.6 6.6 0.27 11.6 6.6 1.4 1 0 0 1 1 1 0 Fez1 ATG16 PF08614.11 KII87229.1 - 0.14 12.4 8.2 0.3 11.3 8.2 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-rbx1 PF12678.7 KII87229.1 - 0.16 12.3 6.1 0.73 10.2 6.1 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Cep57_CLD PF14073.6 KII87229.1 - 0.3 11.1 10.3 0.49 10.4 10.3 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TerY_C PF15616.6 KII87229.1 - 0.36 11.0 2.4 0.65 10.1 0.3 2.1 2 0 0 2 2 2 0 TerY-C metal binding domain DUF1664 PF07889.12 KII87229.1 - 0.78 9.8 4.7 1.4 9.0 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KII87229.1 - 1.4 8.1 7.6 2.4 7.3 7.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 KII87229.1 - 7.7 6.8 11.6 0.65 10.2 2.5 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Plavaka PF18759.1 KII87233.1 - 4.6e-51 174.0 0.2 6.7e-51 173.4 0.2 1.2 1 0 0 1 1 1 1 Plavaka transposase CDC45 PF02724.14 KII87233.1 - 0.7 8.1 8.3 0.98 7.6 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KII87234.1 - 0.076 12.3 5.4 0.12 11.7 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 KII87234.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KII87234.1 - 0.18 11.5 7.3 0.32 10.7 7.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cnd2 PF05786.14 KII87236.1 - 0.15 10.7 0.1 0.18 10.5 0.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Dicty_REP PF05086.12 KII87237.1 - 1.8 6.4 3.4 2.4 6.0 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_Phos_2 PF00328.22 KII87239.1 - 1.1e-30 107.3 0.0 1.2e-30 107.1 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RINGv PF12906.7 KII87240.1 - 1.4e-15 57.2 7.0 2.5e-15 56.3 7.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KII87240.1 - 0.023 15.0 8.9 0.039 14.3 8.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KII87240.1 - 2 8.3 8.3 3.6 7.5 8.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KII87240.1 - 3.6 7.5 6.4 6.6 6.7 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 KII87241.1 - 2.8e-29 100.9 7.3 7.1e-17 61.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DHBP_synthase PF00926.19 KII87242.1 - 9.1e-88 292.8 0.2 1.1e-87 292.6 0.2 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PS_Dcarbxylase PF02666.15 KII87243.1 - 2.7e-54 183.8 0.0 4.8e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Asp PF00026.23 KII87244.1 - 4.9e-35 121.5 0.6 2.3e-22 79.8 4.2 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KII87244.1 - 3.6e-06 27.5 2.1 0.001 19.7 0.5 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.6 KII87244.1 - 4.4e-06 27.1 5.3 0.001 19.4 4.6 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KII87244.1 - 0.15 12.6 0.4 1.6 9.3 0.1 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease PS_Dcarbxylase PF02666.15 KII87245.1 - 0.0035 16.9 4.1 0.06 12.9 2.1 2.3 1 1 0 2 2 2 2 Phosphatidylserine decarboxylase adh_short PF00106.25 KII87246.1 - 4.5e-46 156.8 2.0 5.6e-46 156.5 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87246.1 - 4e-33 114.9 0.8 5.1e-33 114.6 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KII87246.1 - 2.6e-06 27.5 0.8 3.4e-06 27.1 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII87246.1 - 3.3e-06 26.8 0.1 4.7e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII87246.1 - 2.8e-05 24.1 1.5 4.9e-05 23.3 1.5 1.4 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 KII87246.1 - 0.00047 20.4 0.1 0.00075 19.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 KII87246.1 - 0.00086 18.9 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 KII87246.1 - 0.0016 18.4 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KII87246.1 - 0.021 14.2 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gate PF07670.14 KII87246.1 - 0.035 14.4 0.1 0.084 13.1 0.1 1.7 1 1 0 1 1 1 0 Nucleoside recognition RmlD_sub_bind PF04321.17 KII87246.1 - 0.051 12.7 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.10 KII87246.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) PAE PF03283.13 KII87246.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase RTC4 PF14474.6 KII87247.1 - 6.5e-28 97.3 0.0 1.3e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain DUF3719 PF12516.8 KII87247.1 - 0.039 13.7 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) DUF4632 PF15451.6 KII87247.1 - 3.5 7.8 9.1 0.76 9.9 3.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) RCDG1 PF15725.5 KII87249.1 - 0.033 14.6 2.1 0.042 14.3 2.1 1.2 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Smac_DIABLO PF09057.10 KII87250.1 - 0.017 14.4 2.3 0.028 13.8 2.3 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Nnf1 PF03980.14 KII87251.1 - 1.2e-12 48.1 2.0 1.9e-12 47.5 2.0 1.3 1 0 0 1 1 1 1 Nnf1 CASP_C PF08172.12 KII87251.1 - 0.0032 16.8 0.5 0.0045 16.4 0.5 1.1 1 0 0 1 1 1 1 CASP C terminal TSC22 PF01166.18 KII87251.1 - 0.22 11.9 1.1 22 5.4 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Asp PF00026.23 KII87254.1 - 3.9e-66 223.6 5.7 5.9e-66 223.0 5.7 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII87254.1 - 2.6e-12 47.4 3.1 3.4e-07 30.7 0.2 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII87254.1 - 0.0096 16.5 0.6 0.17 12.6 0.1 3.0 2 1 0 2 2 2 1 Aspartyl protease Methyltransf_16 PF10294.9 KII87255.1 - 1.3e-27 96.7 0.0 1.8e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KII87255.1 - 0.0058 17.4 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KII87255.1 - 0.056 12.9 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 KII87255.1 - 0.071 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KII87255.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KII87255.1 - 0.2 12.4 0.0 0.47 11.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Rhomboid PF01694.22 KII87256.1 - 1.9e-19 70.1 12.8 1.4e-18 67.4 12.8 2.1 1 1 0 1 1 1 1 Rhomboid family Staph_opine_DH PF10100.9 KII87256.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase Histone PF00125.24 KII87257.1 - 1.4e-49 167.8 3.9 1.6e-49 167.6 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KII87257.1 - 2.4e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KII87257.1 - 9e-05 22.6 1.2 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KII87257.1 - 0.0013 19.3 2.1 0.0017 19.0 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KII87257.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KII87257.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KII87257.1 - 0.088 12.9 0.1 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KII87258.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KII87258.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KII87258.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KII87258.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII87258.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KII87258.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit adh_short PF00106.25 KII87259.1 - 5.5e-20 71.7 0.2 7.5e-20 71.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87259.1 - 2.3e-17 63.3 0.2 2.9e-17 63.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KII87259.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII87259.1 - 2.5e-06 27.1 0.1 5.5e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KII87259.1 - 0.00094 19.1 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KII87259.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.16 KII87260.1 - 1.9e-15 56.6 41.2 1.9e-15 56.6 41.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily RhoGAP PF00620.27 KII87261.1 - 2.2e-46 157.4 0.0 5e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KII87261.1 - 7.8e-15 54.9 0.7 7e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5344 PF17279.2 KII87261.1 - 0.0032 18.0 4.1 7.8 7.2 1.1 4.4 3 1 1 4 4 4 1 Family of unknown function (DUF5344) SOG2 PF10428.9 KII87261.1 - 0.0093 15.2 5.4 0.019 14.2 5.4 1.4 1 0 0 1 1 1 1 RAM signalling pathway protein Glucodextran_B PF09136.10 KII87261.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Glucodextranase, domain B DUF1664 PF07889.12 KII87261.1 - 0.11 12.5 3.7 5.8 7.0 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KII87261.1 - 0.13 11.8 1.9 0.29 10.6 1.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 KII87261.1 - 0.18 11.9 0.9 18 5.4 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF745 PF05335.13 KII87261.1 - 0.29 10.9 2.5 0.68 9.6 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 KII87261.1 - 0.5 10.6 6.7 0.87 9.8 4.7 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SKA2 PF16740.5 KII87261.1 - 0.58 10.0 6.6 0.99 9.2 4.2 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Syntaxin-6_N PF09177.11 KII87261.1 - 0.69 10.5 5.1 4 8.1 2.2 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 KII87261.1 - 0.81 9.8 8.9 0.65 10.1 4.4 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TMPIT PF07851.13 KII87261.1 - 1 8.6 4.7 2.6 7.2 4.7 1.6 2 0 0 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 KII87261.1 - 1.8 8.6 12.5 1 9.4 9.7 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 KII87261.1 - 2 8.7 3.9 2.3 8.5 1.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-RING_11 PF17123.5 KII87263.1 - 0.013 15.2 0.3 0.66 9.8 0.1 2.7 2 0 0 2 2 2 0 RING-like zinc finger Nucleopor_Nup85 PF07575.13 KII87265.1 - 7.4e-61 206.4 0.0 7.3e-39 133.8 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin TPR_2 PF07719.17 KII87266.1 - 3.6e-07 29.8 0.7 0.012 15.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII87266.1 - 6.7e-06 25.7 0.8 0.17 11.8 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII87266.1 - 0.00047 20.4 0.4 1.3 9.4 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII87266.1 - 0.0021 18.1 0.1 0.054 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII87266.1 - 0.011 16.3 0.3 0.79 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII87266.1 - 0.021 15.6 0.1 3.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KII87266.1 - 0.048 13.7 0.2 2.1 8.5 0.0 2.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KII87266.1 - 0.057 13.1 0.3 0.47 10.2 0.0 2.6 3 0 0 3 3 3 0 TPR repeat DUF3856 PF12968.7 KII87266.1 - 0.066 13.3 0.1 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) DUF2183 PF09949.9 KII87267.1 - 1.3e-26 92.8 0.0 2.8e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) PTS_2-RNA PF01885.16 KII87268.1 - 6.4e-69 231.6 0.4 7.2e-69 231.4 0.4 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Methyltransf_16 PF10294.9 KII87269.1 - 2.2e-21 76.4 0.0 3.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KII87269.1 - 5.3e-06 26.4 0.0 7.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII87269.1 - 0.00049 20.7 0.0 0.00098 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII87269.1 - 0.018 15.7 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KII87269.1 - 0.028 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) F-box-like PF12937.7 KII87270.1 - 0.01 15.7 0.5 0.042 13.7 0.1 2.2 2 0 0 2 2 2 0 F-box-like TauD PF02668.16 KII87271.1 - 1.6e-22 80.6 0.0 7.4e-22 78.4 0.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KII87271.1 - 0.056 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 CsiD Ntox10 PF15520.6 KII87271.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 10 MFS_1 PF07690.16 KII87272.1 - 1.8e-15 56.8 38.1 1.8e-15 56.8 38.1 1.9 2 1 1 3 3 3 2 Major Facilitator Superfamily CENP-T_C PF15511.6 KII87273.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KII87273.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KII87273.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KII87273.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII87273.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KII87273.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KII87274.1 - 1.4e-49 167.8 3.9 1.6e-49 167.6 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KII87274.1 - 2.4e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KII87274.1 - 9e-05 22.6 1.2 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KII87274.1 - 0.0013 19.3 2.1 0.0017 19.0 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KII87274.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KII87274.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KII87274.1 - 0.088 12.9 0.1 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit SIR2 PF02146.17 KII87275.1 - 2.6e-60 203.4 0.0 4.3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KII87275.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KII87275.1 - 0.038 13.7 0.1 9.7 5.9 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.6 KII87276.1 - 4e-30 105.1 0.0 6.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII87276.1 - 9.8e-21 74.1 0.0 1.4e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KII87276.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KII87276.1 - 0.059 13.4 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 KII87276.1 - 0.078 13.0 0.1 11 6.0 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 KII87276.1 - 0.13 12.1 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pox_Ag35 PF03286.14 KII87277.1 - 5.6e-05 23.0 7.5 9.2e-05 22.3 7.5 1.4 1 0 0 1 1 1 1 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 KII87277.1 - 0.00034 21.0 11.4 0.00049 20.4 11.4 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.14 KII87277.1 - 0.0069 16.8 18.1 0.011 16.2 18.1 1.3 1 0 0 1 1 1 1 Prothymosin/parathymosin family PPP4R2 PF09184.11 KII87277.1 - 0.007 16.0 8.7 0.0068 16.0 8.7 1.2 1 0 0 1 1 1 1 PPP4R2 Nop53 PF07767.11 KII87277.1 - 0.81 9.0 14.9 0.98 8.7 14.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TLP-20 PF06088.11 KII87277.1 - 0.81 9.6 4.7 1.1 9.1 4.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FYDLN_acid PF09538.10 KII87277.1 - 1.4 9.7 15.2 2.7 8.7 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4746 PF15928.5 KII87277.1 - 1.4 8.3 12.1 1.8 7.9 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 KII87277.1 - 1.5 8.0 17.2 1.9 7.7 17.2 1.1 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 KII87277.1 - 2 7.1 5.6 2.4 6.9 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sporozoite_P67 PF05642.11 KII87277.1 - 2.1 6.3 6.7 2.5 6.1 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 KII87277.1 - 8.1 5.1 6.3 8.8 5.0 6.3 1.1 1 0 0 1 1 1 0 Presenilin ECR1_N PF14382.6 KII87278.1 - 4.7e-16 58.3 0.5 1.3e-15 56.9 0.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KII87278.1 - 1.1e-14 54.5 0.1 2e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KII87278.1 - 0.038 14.6 0.2 8.9 7.0 0.0 2.5 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 TFIIIC_delta PF12657.7 KII87279.1 - 3.9e-21 75.8 0.2 7.6e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KII87279.1 - 8.4e-21 73.8 1.3 2e-20 72.6 1.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PhnA_Zn_Ribbon PF08274.12 KII87279.1 - 0.078 13.0 0.3 0.28 11.1 0.3 1.9 1 0 0 1 1 1 0 PhnA Zinc-Ribbon YopE PF03545.13 KII87279.1 - 0.15 12.2 0.0 0.46 10.7 0.0 1.8 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) DUF2024 PF09630.10 KII87281.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) zf-MYND PF01753.18 KII87282.1 - 7.8e-07 29.1 15.4 1.4e-06 28.3 15.4 1.4 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 KII87282.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) RRM_1 PF00076.22 KII87283.1 - 1.1e-15 57.2 0.0 1.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KII87283.1 - 0.0069 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 KII87283.1 - 0.056 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo_shadow PF01393.19 KII87284.1 - 4.6e-15 55.4 0.2 2.3e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 KII87284.1 - 1.9e-10 40.5 0.0 5.5e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RGS12_us1 PF16613.5 KII87284.1 - 0.13 12.6 13.0 0.24 11.7 12.4 1.8 1 1 0 1 1 1 0 Unstructured region of RGS12 SOBP PF15279.6 KII87284.1 - 0.15 12.7 4.4 0.2 12.2 4.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ASFV_J13L PF05568.11 KII87285.1 - 0.0099 15.6 7.3 0.0099 15.6 7.3 1.8 1 1 0 1 1 1 1 African swine fever virus J13L protein Isochorismatase PF00857.20 KII87286.1 - 2e-22 80.2 0.0 6.7e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Smr PF01713.21 KII87287.1 - 2.9e-10 40.4 0.0 8.6e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KII87287.1 - 0.0002 21.6 2.5 0.00051 20.4 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF2015 PF09435.10 KII87288.1 - 2.5e-35 120.7 0.0 3e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Glyco_hydro_127 PF07944.12 KII87289.1 - 2e-23 82.7 0.0 3.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 adh_short PF00106.25 KII87291.1 - 1.5e-24 86.6 0.2 1.8e-24 86.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87291.1 - 1.8e-21 76.8 0.6 2.2e-21 76.5 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KII87291.1 - 5.1e-07 29.4 0.1 7.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII87291.1 - 7.5e-05 22.7 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KII87291.1 - 0.00049 19.6 0.1 0.0012 18.3 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KII87291.1 - 0.031 14.2 0.2 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Dynamin_M PF01031.20 KII87295.1 - 0.098 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin central region DUF2560 PF10834.8 KII87295.1 - 0.12 12.6 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) WD40 PF00400.32 KII87296.1 - 6.1e-125 403.5 59.6 2e-10 41.1 0.5 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87296.1 - 1.4e-42 143.9 6.2 0.00038 20.7 0.1 11.4 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII87296.1 - 7.1e-26 90.9 15.8 0.11 11.5 0.0 11.9 1 1 11 12 12 12 11 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KII87296.1 - 1.1e-22 80.0 0.0 0.0035 15.7 0.0 8.6 1 1 7 9 9 9 8 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KII87296.1 - 4.3e-22 77.5 9.6 2.2 8.3 0.0 11.9 12 0 0 12 12 12 8 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KII87296.1 - 8.2e-17 61.5 5.0 0.0095 15.3 0.0 7.5 4 3 4 8 8 8 5 WD40-like domain NAGPA PF09992.9 KII87296.1 - 3.9e-08 33.7 5.3 2.2 8.5 0.0 6.1 2 2 3 6 6 6 2 Phosphodiester glycosidase UN_NPL4 PF11543.8 KII87296.1 - 9.1e-05 22.9 1.9 28 5.3 0.0 7.7 10 2 1 11 11 11 0 Nuclear pore localisation protein NPL4 VMR2 PF17055.5 KII87296.1 - 0.00042 20.1 0.1 0.92 9.2 0.0 4.8 1 1 4 7 7 7 1 Viral matrix protein M2 FLYWCH PF04500.16 KII87296.1 - 0.00081 19.5 0.0 0.33 11.1 0.0 4.2 4 0 0 4 4 3 1 FLYWCH zinc finger domain WD40_3 PF15911.5 KII87296.1 - 0.002 18.1 6.7 1.1e+02 3.0 0.0 7.3 8 0 0 8 8 8 0 WD domain, G-beta repeat DUF2244 PF10003.9 KII87296.1 - 0.0037 16.9 0.0 15 5.3 0.0 4.6 4 1 2 6 6 6 0 Integral membrane protein (DUF2244) 3A PF00803.18 KII87296.1 - 0.039 13.2 2.3 6.6 6.0 0.0 3.5 2 1 2 4 4 4 0 3A/RNA2 movement protein family DUF1258 PF06869.12 KII87296.1 - 0.049 13.1 0.1 2.8 7.3 0.0 3.3 2 2 3 5 5 5 0 Protein of unknown function (DUF1258) Proteasome_A_N PF10584.9 KII87296.1 - 0.1 12.3 28.3 24 4.7 0.0 10.2 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DUF463 PF04317.12 KII87297.1 - 0.0059 15.6 0.9 0.058 12.3 0.9 2.0 1 1 0 1 1 1 1 YcjX-like family, DUF463 DUF1368 PF07112.11 KII87297.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) DUF4413 PF14372.6 KII87298.1 - 4.5e-05 23.8 0.1 5.7e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) adh_short PF00106.25 KII87299.1 - 1.2e-18 67.3 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87299.1 - 1.2e-13 51.2 0.0 1.5e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2457 PF10446.9 KII87300.1 - 0.051 12.7 5.2 0.054 12.6 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cornifin PF02389.15 KII87304.1 - 6.7e-10 39.3 31.5 1.1e-09 38.6 31.4 1.5 1 1 0 1 1 1 1 Cornifin (SPRR) family DDE_1 PF03184.19 KII87308.1 - 1.6e-23 83.3 0.0 2.2e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KII87308.1 - 0.00063 19.5 0.0 0.0023 17.7 0.0 1.9 2 1 1 3 3 3 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KII87308.1 - 0.0019 18.2 0.2 0.011 15.8 0.0 2.3 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain Cucumo_2B PF03263.13 KII87310.1 - 0.056 13.9 2.0 0.11 13.0 2.0 1.6 1 1 0 1 1 1 0 Cucumovirus protein 2B NB-ARC PF00931.22 KII87311.1 - 3.9e-06 26.2 0.0 7.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KII87311.1 - 4.3e-06 26.7 0.0 1.7e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII87311.1 - 0.00023 21.6 0.0 0.00051 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KII87311.1 - 0.0032 18.0 0.0 0.0079 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KII87311.1 - 0.0059 17.0 0.2 0.064 13.7 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 KII87311.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 KII87311.1 - 0.01 15.7 0.1 0.02 14.8 0.1 1.5 1 1 0 1 1 1 0 NTPase APS_kinase PF01583.20 KII87311.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 KII87311.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KII87311.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KII87311.1 - 0.071 12.9 0.2 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KII87311.1 - 0.11 12.8 0.0 0.51 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KII87311.1 - 0.12 12.5 0.0 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 KII87311.1 - 0.15 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase ATPase_2 PF01637.18 KII87311.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PGM_PMM_I PF02878.16 KII87312.1 - 3.4e-37 127.2 0.2 5.9e-37 126.5 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KII87312.1 - 2.3e-26 92.2 0.0 4.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KII87312.1 - 2.3e-13 50.6 0.0 9.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KII87312.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MFS_1 PF07690.16 KII87313.1 - 6.9e-19 68.0 37.7 1e-18 67.4 37.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chordopox_A13L PF05961.11 KII87313.1 - 0.06 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Hydantoinase_B PF02538.14 KII87314.1 - 1e-191 637.9 5.0 3.6e-191 636.1 4.6 2.0 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KII87314.1 - 2.2e-99 332.4 0.5 2.2e-99 332.4 0.5 2.3 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KII87314.1 - 3.1e-63 212.7 2.2 3.5e-62 209.2 0.0 2.6 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region ERG4_ERG24 PF01222.17 KII87315.1 - 3.8e-128 427.9 24.4 4.4e-128 427.7 24.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KII87315.1 - 3.8e-05 23.3 2.8 8e-05 22.3 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KII87315.1 - 0.014 15.8 1.2 0.036 14.5 0.1 2.3 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4017 PF13209.6 KII87315.1 - 5.6 7.0 8.4 4.1 7.4 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4017) Carb_kinase PF01256.17 KII87316.1 - 2.3e-50 171.3 0.0 4.1e-49 167.2 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KII87316.1 - 0.077 12.4 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase Methyltransf_2 PF00891.18 KII87317.1 - 1.6e-25 89.6 0.1 3.2e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_23 PF13489.6 KII87317.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TFIID-18kDa PF02269.16 KII87317.1 - 0.12 12.5 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit MTS PF05175.14 KII87317.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Zw10 PF06248.13 KII87318.1 - 4.8e-23 81.5 0.0 1.2e-16 60.5 0.0 3.8 3 1 0 3 3 3 3 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KII87318.1 - 2.8e-08 33.7 0.1 9.4e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal VPS13_C PF16909.5 KII87318.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Baculo_PEP_C PF04513.12 KII87318.1 - 0.63 10.1 3.1 1.7 8.7 0.9 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 KII87319.1 - 1.6e-08 35.1 5.0 0.52 11.3 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat NCE101 PF11654.8 KII87320.1 - 0.019 14.7 0.6 0.025 14.3 0.5 1.4 1 1 0 1 1 1 0 Non-classical export protein 1 DnaJ PF00226.31 KII87321.1 - 7.8e-24 83.6 0.1 1.3e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KII87321.1 - 1e-21 77.1 0.0 2.1e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) F-box PF00646.33 KII87322.1 - 0.00011 22.0 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 KII87322.1 - 0.00012 21.8 0.3 0.00026 20.7 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII87322.1 - 0.00015 21.6 0.7 0.00039 20.3 0.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.7 KII87322.1 - 0.00025 20.9 0.0 0.00081 19.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 KII87322.1 - 0.00088 19.3 0.5 0.002 18.1 0.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KII87322.1 - 0.0045 17.5 0.5 0.27 12.0 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII87322.1 - 0.0084 16.9 1.3 0.034 14.9 1.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box_4 PF15966.5 KII87322.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box TPR_7 PF13176.6 KII87322.1 - 0.018 15.0 1.1 0.085 12.9 1.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 KII87322.1 - 0.029 14.2 0.6 0.086 12.7 0.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII87322.1 - 0.035 14.4 0.4 0.077 13.3 0.4 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SSFA2_C PF14723.6 KII87322.1 - 0.37 10.7 2.6 0.9 9.4 0.2 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus BCS1_N PF08740.11 KII87323.1 - 2.3e-39 135.3 0.8 3.8e-39 134.6 0.8 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KII87323.1 - 3.9e-15 56.4 0.0 2.7e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KII87323.1 - 0.0037 16.4 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KII87323.1 - 0.0049 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KII87323.1 - 0.023 14.6 0.2 0.068 13.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KII87323.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KII87323.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KII87323.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KII87323.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 KII87323.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 KII87323.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KII87323.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KII87323.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KII87323.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KII87323.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII87323.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Thymidylat_synt PF00303.19 KII87324.1 - 5e-103 343.9 0.0 5.8e-103 343.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase ubiquitin PF00240.23 KII87325.1 - 1.6e-34 117.5 0.5 3.4e-34 116.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 KII87325.1 - 2.2e-26 91.8 2.1 2.2e-26 91.8 2.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KII87325.1 - 3.8e-16 58.7 0.6 7.9e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KII87325.1 - 2.4e-05 24.7 0.4 0.00014 22.2 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KII87325.1 - 0.00028 20.9 0.6 0.00064 19.8 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KII87325.1 - 0.0065 16.8 1.0 0.012 15.9 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KII87325.1 - 0.0072 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KII87325.1 - 0.0073 16.9 0.8 0.01 16.4 0.8 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KII87325.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 KII87325.1 - 0.028 14.6 0.7 0.045 14.0 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Rep_fac_C PF08542.11 KII87326.1 - 4.3e-23 81.5 0.0 1.5e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KII87326.1 - 8.4e-18 65.1 0.0 1.6e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KII87326.1 - 1.9e-15 57.0 0.0 2.1e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KII87326.1 - 8.5e-09 35.6 0.0 4e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KII87326.1 - 4.9e-07 29.7 0.0 1.9e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KII87326.1 - 6.3e-06 26.3 0.3 2.3e-05 24.5 0.1 2.1 2 1 1 3 3 2 1 AAA domain AAA_assoc_2 PF16193.5 KII87326.1 - 8.4e-06 26.0 0.1 2.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 AAA C-terminal domain DUF815 PF05673.13 KII87326.1 - 1.2e-05 24.6 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KII87326.1 - 2.1e-05 24.5 0.1 5.1e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KII87326.1 - 5.3e-05 23.5 1.1 0.27 11.5 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.6 KII87326.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII87326.1 - 8.4e-05 22.9 0.3 0.013 15.8 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII87326.1 - 0.00011 22.6 0.0 0.00043 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 KII87326.1 - 0.00012 21.9 1.2 0.00039 20.2 0.5 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase RuvB_N PF05496.12 KII87326.1 - 0.00012 21.8 0.0 0.00033 20.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KII87326.1 - 0.00025 21.1 0.0 0.0068 16.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KII87326.1 - 0.00042 20.2 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KII87326.1 - 0.00079 19.4 0.1 0.0077 16.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KII87326.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 KII87326.1 - 0.0036 16.8 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KII87326.1 - 0.0043 16.5 0.1 0.22 10.9 0.0 2.5 2 1 1 3 3 3 1 Bacterial TniB protein Viral_helicase1 PF01443.18 KII87326.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KII87326.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KII87326.1 - 0.024 14.5 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KII87326.1 - 0.024 13.7 0.0 0.08 12.0 0.0 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein MCM PF00493.23 KII87326.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain SNF2_N PF00176.23 KII87326.1 - 0.031 13.0 0.0 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 KII87326.1 - 0.05 13.0 0.0 0.46 9.8 0.0 2.1 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 KII87326.1 - 0.05 12.8 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase Methyltransf_31 PF13847.6 KII87326.1 - 0.055 13.3 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain AAA_28 PF13521.6 KII87326.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain TPR_6 PF13174.6 KII87326.1 - 0.1 13.3 1.7 2.4 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fapy_DNA_glyco PF01149.24 KII87327.1 - 0.062 13.9 0.0 0.21 12.2 0.0 1.8 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain DUF1749 PF08538.10 KII87327.1 - 0.15 11.1 0.0 0.42 9.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) RED_N PF07808.13 KII87329.1 - 2.7e-16 59.9 12.8 7.1e-16 58.5 12.8 1.8 1 0 0 1 1 1 1 RED-like protein N-terminal region MMgT PF10270.9 KII87330.1 - 4.5e-10 39.8 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter F-box-like PF12937.7 KII87333.1 - 1.2e-05 25.0 0.7 3.6e-05 23.6 0.5 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII87333.1 - 0.00016 22.0 0.2 2.1 8.9 0.0 4.9 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) SIR2 PF02146.17 KII87334.1 - 7.6e-33 113.9 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family adh_short_C2 PF13561.6 KII87334.1 - 0.047 13.2 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 KII87335.1 - 4.4e-24 84.3 13.9 0.0012 19.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KII87335.1 - 0.0037 16.3 0.1 0.46 9.4 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PET117 PF15786.5 KII87336.1 - 7e-25 87.1 1.3 8e-25 86.9 1.3 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4500 PF14937.6 KII87336.1 - 0.00057 19.8 0.0 0.00098 19.1 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4500) MAS20 PF02064.15 KII87336.1 - 0.031 14.4 0.5 0.038 14.1 0.5 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor CbtB PF09489.10 KII87336.1 - 0.034 14.3 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) CTD_bind PF04818.13 KII87337.1 - 1.4e-06 29.1 0.2 2.2e-05 25.2 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase II-binding domain. PAP2 PF01569.21 KII87338.1 - 1.4e-25 89.7 3.3 7.5e-25 87.3 0.8 2.2 1 1 1 2 2 2 2 PAP2 superfamily UbiA PF01040.18 KII87339.1 - 9.5e-22 77.5 13.1 1.3e-21 77.0 13.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family TMEM223 PF14640.6 KII87339.1 - 0.12 12.5 0.2 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 223 SNF2_N PF00176.23 KII87340.1 - 2.1e-17 62.9 0.1 3e-13 49.2 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KII87340.1 - 6.7e-17 61.8 0.0 2e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KII87340.1 - 2.6e-06 27.8 0.1 1.9e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII87340.1 - 0.0021 18.1 0.2 0.047 13.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cript PF10235.9 KII87341.1 - 8.7e-29 99.9 4.9 8.7e-29 99.9 4.9 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KII87341.1 - 0.00091 19.2 9.9 0.0017 18.3 5.8 2.2 1 1 1 2 2 2 1 Double zinc ribbon DUF2039 PF10217.9 KII87341.1 - 0.0058 16.9 7.1 0.0058 16.9 7.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 KII87341.1 - 0.0083 15.8 14.8 3.9 7.3 0.0 3.3 3 0 0 3 3 3 3 zinc-ribbon domain Rhodanese_C PF12368.8 KII87341.1 - 0.02 15.3 6.4 0.047 14.1 2.0 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal Gin PF10764.9 KII87341.1 - 0.061 13.3 7.6 0.37 10.8 0.0 3.1 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin zf_UBZ PF18439.1 KII87341.1 - 0.093 12.3 9.2 1.9 8.1 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1272 PF06906.11 KII87341.1 - 0.18 11.9 5.9 0.5 10.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-dskA_traR PF01258.17 KII87341.1 - 0.78 9.7 8.8 15 5.7 0.0 4.0 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Sgf11 PF08209.11 KII87341.1 - 0.79 9.3 6.6 27 4.4 0.1 3.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.12 KII87341.1 - 0.99 9.4 14.0 13 5.9 14.0 2.1 1 1 0 1 1 1 0 zinc-ribbons NOB1_Zn_bind PF08772.11 KII87341.1 - 1.8 8.8 11.7 3.8 7.7 4.1 2.9 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PLATZ PF04640.14 KII87341.1 - 8 7.2 10.8 2.2 9.0 2.3 2.9 1 1 2 3 3 3 0 PLATZ transcription factor Methyltransf_16 PF10294.9 KII87342.1 - 8.1e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KII87342.1 - 0.048 13.2 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KII87342.1 - 0.053 14.2 0.0 0.097 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KII87342.1 - 0.074 13.8 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KII87342.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF2817 PF10994.8 KII87342.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) SnAC PF14619.6 KII87343.1 - 0.059 14.0 0.5 0.29 11.8 0.5 2.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex Cript PF10235.9 KII87343.1 - 0.83 10.3 8.5 0.33 11.6 0.9 3.1 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT Cu-oxidase PF00394.22 KII87344.1 - 4.3e-49 166.7 0.2 1.3e-44 152.1 0.0 2.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII87344.1 - 6.3e-37 126.4 2.2 7.5e-35 119.6 0.0 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII87344.1 - 6e-35 119.8 0.2 1.4e-33 115.5 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KII87346.1 - 3.5e-48 163.7 0.0 1.7e-44 151.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII87346.1 - 2.4e-39 134.2 1.5 4.3e-36 123.7 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII87346.1 - 1.1e-35 122.2 0.3 2.8e-34 117.7 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Zn_clus PF00172.18 KII87350.1 - 3.4e-24 84.7 78.1 3.7e-07 30.2 10.6 5.1 4 1 1 5 5 5 4 Fungal Zn(2)-Cys(6) binuclear cluster domain DWNN PF08783.11 KII87351.1 - 1e-30 105.8 0.3 2.5e-30 104.6 0.3 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KII87351.1 - 3.7e-10 39.4 5.7 8.7e-10 38.2 5.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KII87351.1 - 1.9e-06 27.7 1.6 4.3e-06 26.6 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KII87351.1 - 0.00016 21.5 1.0 0.00042 20.2 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KII87351.1 - 0.003 17.7 0.5 0.0091 16.2 0.0 2.1 2 0 0 2 2 1 1 U-box domain zf-C3HC4_3 PF13920.6 KII87351.1 - 0.0059 16.5 5.2 0.0059 16.5 5.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII87351.1 - 0.011 16.0 6.9 0.033 14.5 6.9 1.8 1 0 0 1 1 1 0 Ring finger domain Menin PF05053.13 KII87351.1 - 0.051 11.9 2.9 0.098 11.0 2.9 1.4 1 0 0 1 1 1 0 Menin zf-CCHC_5 PF14787.6 KII87351.1 - 0.056 13.2 0.5 0.056 13.2 0.5 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-RING_UBOX PF13445.6 KII87351.1 - 0.094 12.8 6.6 0.24 11.4 6.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Trm112p PF03966.16 KII87351.1 - 0.12 13.0 0.1 1.3 9.7 0.1 2.4 2 0 0 2 2 2 0 Trm112p-like protein zf-C3HC4_2 PF13923.6 KII87351.1 - 0.59 10.0 15.0 0.027 14.3 8.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII87351.1 - 1.1 9.5 8.6 3.3 7.9 8.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KII87351.1 - 1.1 9.1 8.3 2.7 7.9 8.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII87351.1 - 3.2 7.8 12.2 0.37 10.8 6.3 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf_UBZ PF18439.1 KII87351.1 - 3.8 7.2 6.8 3.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Vps5 PF09325.10 KII87352.1 - 4.7e-68 229.3 3.1 6.9e-68 228.7 3.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KII87352.1 - 2.3e-27 95.2 0.2 2.2e-26 92.1 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR PF03114.18 KII87352.1 - 2.3e-05 24.2 1.4 3.4e-05 23.6 1.4 1.1 1 0 0 1 1 1 1 BAR domain FAM92 PF06730.11 KII87352.1 - 7.5e-05 22.3 2.7 0.00014 21.4 2.7 1.3 1 0 0 1 1 1 1 FAM92 protein Arfaptin PF06456.13 KII87352.1 - 0.0016 18.0 1.2 0.019 14.5 1.4 2.0 1 1 0 1 1 1 1 Arfaptin-like domain BAR_3_WASP_bdg PF10456.9 KII87352.1 - 0.0053 16.2 1.3 0.13 11.7 1.3 2.2 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 KII87352.1 - 0.27 10.9 2.0 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 BAR domain of APPL family Ndc1_Nup PF09531.10 KII87352.1 - 2.7 6.6 4.9 4.3 5.9 4.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PMT PF02366.18 KII87353.1 - 1.5e-79 267.0 16.8 1.5e-79 267.0 16.8 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KII87353.1 - 1e-63 214.6 2.1 1e-63 214.6 2.1 3.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KII87353.1 - 7.4e-18 65.1 0.7 1.2e-17 64.4 0.7 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KII87353.1 - 2.7e-06 27.7 11.1 2.7e-06 27.7 11.1 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PX PF00787.24 KII87354.1 - 1.2e-15 57.4 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 PX domain Glyoxalase PF00903.25 KII87355.1 - 5.4e-05 23.4 0.1 0.00015 22.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_hydro_3_C PF01915.22 KII87356.1 - 1.6e-51 175.2 0.0 2.6e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII87356.1 - 7e-38 130.8 0.0 1.1e-37 130.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII87356.1 - 9.1e-23 80.2 0.3 2.1e-22 79.0 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Med3 PF11593.8 KII87356.1 - 2.5 7.2 12.6 4 6.5 12.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ADH_N PF08240.12 KII87357.1 - 1.1e-24 86.4 0.6 1.1e-24 86.4 0.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII87357.1 - 1.1e-15 57.8 0.0 1.5e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII87357.1 - 2.8e-05 23.7 0.0 0.0013 18.2 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII87357.1 - 0.14 13.2 0.0 0.29 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 KII87358.1 - 3e-58 197.3 0.0 2.8e-57 194.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87358.1 - 3.2e-24 85.6 0.1 7.9e-19 67.9 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KII87358.1 - 1.4e-05 24.2 0.1 2.6e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KII87358.1 - 0.00038 19.6 0.0 0.00079 18.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 KII87358.1 - 0.0015 17.9 1.1 0.03 13.6 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KII87358.1 - 0.0031 16.9 0.6 0.0076 15.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII87358.1 - 0.0055 16.6 0.5 0.17 11.7 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII87358.1 - 0.011 14.5 0.7 0.017 13.9 0.7 1.4 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KII87358.1 - 0.14 11.7 2.5 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 KII87359.1 - 1.5e-43 145.9 9.1 8e-08 32.8 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87359.1 - 1.5e-14 54.1 0.0 0.075 13.3 0.0 6.0 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KII87359.1 - 2.7e-13 49.2 1.0 6.6e-13 48.0 1.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 KII87359.1 - 7.5e-06 25.1 0.0 1.3 7.9 0.0 4.1 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KII87359.1 - 5.4e-05 22.7 0.0 0.071 12.4 0.0 3.2 4 0 0 4 4 4 2 WD40-like domain Nbas_N PF15492.6 KII87359.1 - 0.00047 19.6 0.0 2.5 7.4 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KII87359.1 - 0.12 11.0 4.6 3.1 6.3 0.1 3.9 3 1 2 5 5 5 0 Nucleoporin Nup120/160 Ank_2 PF12796.7 KII87360.1 - 3.5e-11 43.6 0.1 8.5e-05 23.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII87360.1 - 1.5e-09 38.2 0.1 8.3e-06 26.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII87360.1 - 2.4e-09 37.3 0.2 0.0041 17.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII87360.1 - 5.1e-09 35.6 0.4 0.03 14.9 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KII87360.1 - 6.2e-09 35.9 4.0 0.00052 20.4 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KII87360.1 - 0.00026 20.8 0.0 0.0091 15.8 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain DUF1664 PF07889.12 KII87360.1 - 0.036 14.1 1.3 0.23 11.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 KII87360.1 - 0.063 12.9 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF2605 PF10792.9 KII87360.1 - 0.066 13.1 0.1 0.6 10.1 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) DUF3562 PF12085.8 KII87360.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) PDH PF02153.17 KII87360.1 - 0.16 10.9 0.2 0.42 9.6 0.0 1.7 2 0 0 2 2 2 0 Prephenate dehydrogenase Ion_trans PF00520.31 KII87361.1 - 8.5e-06 25.2 20.3 1.6e-05 24.3 20.3 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KII87361.1 - 0.0074 15.0 16.2 0.025 13.3 0.5 2.3 2 0 0 2 2 2 2 Polycystin cation channel DUF2304 PF10066.9 KII87361.1 - 0.7 10.1 7.1 0.14 12.4 2.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) EHN PF06441.12 KII87362.1 - 1.3e-27 96.3 1.0 1.8e-27 95.9 0.1 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII87362.1 - 6.7e-12 45.6 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII87362.1 - 3.3e-08 34.4 1.4 5.4e-08 33.7 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.12 KII87364.1 - 2.6e-33 114.6 0.2 4.3e-33 113.9 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.7 KII87364.1 - 5.8e-10 40.1 2.9 8.5e-10 39.6 2.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII87364.1 - 2.3e-09 37.3 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TFIIS_M PF07500.14 KII87365.1 - 1.6e-18 67.2 0.0 3.3e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KII87365.1 - 6.9e-16 58.5 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 SPOC domain DUF3915 PF13054.6 KII87365.1 - 3.3 7.7 7.1 8 6.5 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PHD PF00628.29 KII87366.1 - 2.3e-08 33.8 3.7 4e-08 33.0 3.7 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KII87366.1 - 0.023 14.6 2.3 0.037 13.9 2.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4746 PF15928.5 KII87366.1 - 0.17 11.3 2.3 0.25 10.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase PF00069.25 KII87368.1 - 1.6e-69 234.2 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87368.1 - 2.6e-53 181.0 0.0 3.9e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 KII87368.1 - 2.9e-08 33.9 0.0 6.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 KII87368.1 - 1.8e-07 30.9 5.1 3.1e-07 30.2 5.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KII87368.1 - 4.6e-05 23.0 4.0 8.2e-05 22.1 4.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Kinase-like PF14531.6 KII87368.1 - 0.002 17.5 0.0 0.012 15.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KII87368.1 - 0.02 14.5 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 KII87368.1 - 0.025 14.1 0.2 0.045 13.3 0.2 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL C1_2 PF03107.16 KII87368.1 - 0.27 11.6 2.7 0.54 10.6 2.7 1.5 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 KII87368.1 - 0.82 9.6 5.4 1.6 8.7 5.4 1.4 1 0 0 1 1 1 0 PHD-finger EHN PF06441.12 KII87369.1 - 1.2e-31 109.2 0.2 2.2e-31 108.4 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII87369.1 - 2.1e-11 44.0 0.1 4.1e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_18 PF00704.28 KII87370.1 - 1.7e-17 64.1 1.1 2.2e-17 63.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF952 PF06108.12 KII87371.1 - 1.3e-19 70.0 0.0 1.7e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) LMBR1 PF04791.16 KII87374.1 - 0.0015 17.6 0.1 0.0019 17.2 0.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Rop-like PF05082.13 KII87374.1 - 0.052 13.4 0.8 0.58 10.0 0.1 2.4 1 1 2 3 3 3 0 Rop-like WXG100 PF06013.12 KII87374.1 - 0.077 13.2 0.0 9 6.6 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG RPW8 PF05659.11 KII87374.1 - 0.096 12.4 0.0 1.6 8.4 0.0 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Mce4_CUP1 PF11887.8 KII87374.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Methyltransf_23 PF13489.6 KII87375.1 - 2.4e-24 86.0 0.0 3.3e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87375.1 - 9.4e-23 80.7 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII87375.1 - 8.6e-19 68.0 0.1 2.4e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII87375.1 - 2.4e-17 63.5 0.0 3.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII87375.1 - 1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KII87375.1 - 4.8e-08 32.6 0.0 6.5e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KII87375.1 - 1.1e-06 27.9 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KII87375.1 - 5.1e-06 26.1 0.0 7.3e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KII87375.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KII87375.1 - 3.8e-05 23.1 0.0 5.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KII87375.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 KII87375.1 - 0.0027 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 KII87375.1 - 0.0073 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KII87375.1 - 0.0079 15.3 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 KII87375.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.11 KII87375.1 - 0.078 12.6 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) E1-E2_ATPase PF00122.20 KII87376.1 - 1.9e-47 161.1 4.5 1.9e-47 161.1 4.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KII87376.1 - 1.3e-32 113.8 2.0 2e-32 113.2 0.4 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KII87376.1 - 8.7e-26 90.2 0.0 1.7e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KII87376.1 - 0.00026 20.8 0.3 0.0075 16.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KII87376.1 - 2.2 8.3 9.2 3.3 7.8 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) EHN PF06441.12 KII87377.1 - 2e-33 115.0 0.1 3.4e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII87377.1 - 1e-10 41.7 0.1 2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII87377.1 - 3.3e-06 27.9 6.0 5.4e-06 27.2 6.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Dynactin_p22 PF07426.11 KII87378.1 - 8.7e-17 61.5 0.0 1.4e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 Lebercilin PF15619.6 KII87378.1 - 0.022 14.4 0.8 0.022 14.4 0.8 2.0 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T2SSF PF00482.23 KII87378.1 - 0.045 13.7 0.6 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF4744 PF15918.5 KII87379.1 - 0.029 15.2 1.3 0.13 13.2 1.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) ATG16 PF08614.11 KII87379.1 - 0.03 14.5 35.1 0.17 12.1 18.6 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) TFIIA PF03153.13 KII87379.1 - 1.3 8.9 16.6 2.4 8.1 16.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlaC_arch PF05377.11 KII87379.1 - 2.3 8.7 3.8 2.8 8.4 0.4 2.9 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF3552 PF12072.8 KII87379.1 - 2.4 7.5 25.6 2.6 7.4 21.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.8 KII87379.1 - 2.7 8.1 16.2 8.7 6.4 3.4 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 KII87379.1 - 4.6 6.5 13.7 0.55 9.5 8.6 1.8 2 0 0 2 2 2 0 FAM76 protein Filament PF00038.21 KII87379.1 - 5.2 6.5 20.8 2.6 7.6 10.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 KII87379.1 - 7.7 5.3 22.2 0.96 8.3 5.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF676 PF05057.14 KII87380.1 - 1.6e-29 103.0 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KII87380.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KII87380.1 - 0.03 14.1 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Coatomer_E PF04733.14 KII87381.1 - 3.4e-44 151.4 1.1 4e-44 151.2 1.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 KII87381.1 - 0.0013 18.7 0.6 7.5 6.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII87381.1 - 0.0043 17.2 0.1 4.4 7.8 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII87381.1 - 0.11 12.3 0.0 26 4.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII87381.1 - 0.2 12.4 4.4 78 4.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KII87381.1 - 0.44 11.1 12.8 5.4 7.6 1.5 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KII87381.1 - 2.8 8.8 9.5 7.5 7.5 1.9 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.15 KII87382.1 - 5.7e-37 127.5 0.0 1.5e-23 83.2 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KII87382.1 - 8.7e-07 28.0 0.0 0.00058 18.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 DUF1726 PF08351.11 KII87382.1 - 0.072 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) F-box-like PF12937.7 KII87383.1 - 8.8e-08 31.9 0.9 8.8e-08 31.9 0.9 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KII87383.1 - 0.06 13.2 1.2 2.6 8.0 0.0 3.6 2 1 0 2 2 2 0 F-box domain PH_10 PF15411.6 KII87384.1 - 3e-23 82.4 0.0 5.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KII87384.1 - 7.6e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KII87384.1 - 0.00012 22.1 0.0 0.00054 19.9 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KII87384.1 - 0.00016 21.9 2.6 0.00019 21.7 1.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KII87384.1 - 0.00017 21.5 2.7 0.00045 20.2 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KII87384.1 - 0.0095 15.9 0.8 0.032 14.2 1.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII87384.1 - 0.1 12.5 1.8 0.45 10.4 1.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII87384.1 - 0.14 12.0 0.7 0.31 10.9 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KII87384.1 - 8.4 6.2 10.5 0.17 11.7 2.8 2.3 3 0 0 3 3 3 0 RING-like zinc finger PALP PF00291.25 KII87385.1 - 2.3e-54 184.8 2.5 2.6e-54 184.6 2.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Polyketide_cyc2 PF10604.9 KII87385.1 - 0.077 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DOPA_dioxygen PF08883.11 KII87386.1 - 2.3e-45 153.2 0.5 2.8e-45 152.9 0.5 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family dCMP_cyt_deam_1 PF00383.23 KII87388.1 - 7.5e-19 67.5 0.1 1e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KII87388.1 - 5.2e-13 49.4 1.2 3.1e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KII87388.1 - 0.021 14.4 1.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases F-box-like PF12937.7 KII87389.1 - 1.3e-11 44.1 1.7 1.3e-11 44.1 1.7 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII87389.1 - 0.68 9.9 4.7 0.97 9.4 1.8 2.8 2 1 0 2 2 2 0 F-box domain PIF1 PF05970.14 KII87390.1 - 1.3e-08 34.5 0.1 1.6e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KII87390.1 - 6e-05 22.8 0.1 8.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KII87390.1 - 0.00028 20.5 0.1 0.00041 19.9 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KII87390.1 - 0.00059 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KII87390.1 - 0.00079 19.8 0.1 0.0012 19.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KII87390.1 - 0.0024 17.9 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KII87390.1 - 0.0027 17.2 0.1 0.004 16.6 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 KII87390.1 - 0.0037 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KII87390.1 - 0.013 15.4 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 KII87390.1 - 0.016 14.1 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KII87390.1 - 0.025 14.9 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KII87390.1 - 0.046 12.9 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KII87390.1 - 0.049 12.7 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KII87390.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KII87390.1 - 0.081 13.4 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.13 KII87390.1 - 0.085 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KII87390.1 - 0.095 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 KII87390.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 KII87390.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_32 PF13654.6 KII87390.1 - 0.25 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF5605 PF18310.1 KII87392.1 - 0.0055 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5605) UvrD_C_2 PF13538.6 KII87392.1 - 0.0071 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain F-box-like PF12937.7 KII87393.1 - 3.5e-11 42.8 1.3 9.9e-11 41.4 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII87393.1 - 0.0015 18.3 0.4 0.005 16.7 0.4 2.0 1 0 0 1 1 1 1 F-box domain PI3_PI4_kinase PF00454.27 KII87395.1 - 7.1e-53 180.0 0.0 1.3e-52 179.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KII87395.1 - 2.8e-35 121.7 1.0 2.1e-34 118.9 0.2 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KII87395.1 - 4e-11 42.5 0.0 1.2e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KII87395.1 - 2e-08 33.9 2.2 4.7e-08 32.6 2.2 1.6 1 0 0 1 1 1 1 FAT domain Pkinase PF00069.25 KII87396.1 - 1.5e-73 247.4 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87396.1 - 1.9e-48 165.0 0.0 3.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KII87396.1 - 3.2e-23 81.8 0.0 8.2e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KII87396.1 - 4e-06 25.9 0.5 7e-06 25.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KII87396.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII87396.1 - 0.019 14.3 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII87396.1 - 0.037 13.9 0.1 0.37 10.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 KII87396.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain F-box-like PF12937.7 KII87398.1 - 5.4e-12 45.4 1.9 1.6e-11 43.9 1.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII87398.1 - 0.15 12.0 6.8 0.97 9.4 4.3 3.1 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.7 KII87399.1 - 2.3e-10 40.2 1.4 5.7e-10 38.9 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII87399.1 - 2.2 8.2 8.1 3.7 7.5 4.4 3.1 2 1 0 2 2 2 0 F-box domain Plavaka PF18759.1 KII87401.1 - 2.3e-129 431.3 0.0 3.4e-129 430.7 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase COesterase PF00135.28 KII87402.1 - 1.1e-86 291.7 0.0 5.1e-86 289.6 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII87402.1 - 1.4e-09 38.2 0.5 1.7e-08 34.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.7 KII87403.1 - 1.6e-11 43.9 0.5 1.6e-11 43.9 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII87403.1 - 0.0013 18.6 0.5 0.0063 16.4 0.5 2.3 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KII87403.1 - 0.067 13.6 1.4 22 5.6 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF601 PF04642.12 KII87404.1 - 2.4 7.6 12.5 2.3 7.6 11.4 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF601 PseudoU_synth_1 PF01416.20 KII87405.1 - 4e-09 36.9 0.0 9.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KII87405.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) RNA_pol_Rpb4 PF03874.16 KII87406.1 - 2.4e-18 66.6 0.3 3.8e-18 66.0 0.3 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb4 Aa_trans PF01490.18 KII87407.1 - 1.1e-82 278.0 21.2 1.3e-82 277.7 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FGGY_N PF00370.21 KII87408.1 - 1.5e-23 83.6 0.0 2.7e-17 63.2 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KII87408.1 - 6.1e-15 55.5 0.0 1.5e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SUZ PF12752.7 KII87410.1 - 1.6e-16 60.8 4.6 4.6e-16 59.3 4.6 1.7 1 1 0 1 1 1 1 SUZ domain R3H PF01424.22 KII87410.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 R3H domain Pre-SET PF05033.16 KII87412.1 - 1e-15 58.3 5.2 1e-15 58.3 5.2 2.3 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 KII87412.1 - 3.4e-13 50.3 3.1 5.4e-13 49.7 0.0 2.4 2 1 0 2 2 2 1 SET domain Pheromone PF08015.11 KII87412.1 - 6 8.0 11.9 1.3e+04 -2.7 11.9 3.6 1 1 0 1 1 1 0 Fungal mating-type pheromone FMO-like PF00743.19 KII87413.1 - 9e-26 90.4 0.0 3.2e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII87413.1 - 3.6e-13 49.4 0.0 8.5e-11 41.7 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII87413.1 - 7.1e-09 35.3 0.1 2.5e-05 23.6 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KII87413.1 - 2.7e-08 33.4 0.0 0.0021 17.4 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII87413.1 - 3.8e-07 30.2 0.0 7.8e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KII87413.1 - 4.8e-06 26.4 2.6 0.0022 17.6 0.2 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII87413.1 - 1.3e-05 25.3 0.0 4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KII87413.1 - 2.8e-05 24.6 0.2 0.03 14.9 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KII87413.1 - 7.7e-05 22.2 0.5 0.91 8.7 0.0 3.6 3 1 1 4 4 4 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KII87413.1 - 0.034 12.9 0.0 0.38 9.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 KII87413.1 - 0.036 13.5 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KII87413.1 - 0.049 14.1 0.1 2.1 8.8 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding F-box-like PF12937.7 KII87415.1 - 1.3e-12 47.4 2.8 2.2e-12 46.7 0.9 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII87415.1 - 0.36 10.7 4.1 8.5 6.4 0.3 3.5 3 0 0 3 3 3 0 F-box domain Zds_C PF08632.10 KII87416.1 - 1.6e-28 98.2 0.3 2.8e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Rnk_N PF14760.6 KII87416.1 - 0.19 12.2 3.6 1.4 9.4 0.3 2.6 2 0 0 2 2 2 0 Rnk N-terminus Connexin PF00029.19 KII87416.1 - 0.59 9.9 7.3 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Connexin NARP1 PF12569.8 KII87416.1 - 3.3 6.5 17.0 0.16 10.9 1.5 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MOZART1 PF12554.8 KII87417.1 - 1.7e-24 85.3 0.4 2.2e-24 84.9 0.4 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Adaptin_N PF01602.20 KII87418.1 - 2.4e-145 485.1 8.0 2.8e-145 484.8 8.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KII87418.1 - 9e-24 83.9 0.2 9e-24 83.9 0.2 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 KII87418.1 - 6.1e-08 32.9 9.9 1.2e-06 28.7 0.3 3.6 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII87418.1 - 0.00056 20.3 3.7 0.84 10.1 0.1 4.6 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KII87418.1 - 0.0016 18.5 0.1 47 4.6 0.0 4.8 3 0 0 3 3 3 0 HEAT repeat Peptidase_M73 PF12389.8 KII87418.1 - 0.055 13.3 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase MMS19_N PF14500.6 KII87418.1 - 0.075 12.6 0.8 14 5.1 0.0 3.0 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_M PF14666.6 KII87418.1 - 0.085 12.6 0.8 1 9.2 0.1 3.0 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Nucleoporin_FG PF13634.6 KII87418.1 - 1.7 9.6 14.6 5.1 8.0 14.6 1.8 1 1 0 1 1 1 0 Nucleoporin FG repeat region Forkhead PF00250.18 KII87419.1 - 2.9e-25 88.3 0.0 5.5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain DNA_ligase_A_M PF01068.21 KII87420.1 - 1.9e-50 171.4 0.1 3.2e-50 170.6 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KII87420.1 - 2.2e-41 142.1 0.0 5.8e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 KII87420.1 - 6.9e-25 87.3 0.2 4e-11 43.2 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KII87420.1 - 6.2e-17 62.0 0.1 3.4e-16 59.7 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KII87420.1 - 2e-12 47.8 0.1 3.9e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 KII87420.1 - 6.9e-07 29.6 0.0 0.023 15.1 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KII87420.1 - 0.00064 20.0 0.1 0.061 13.6 0.0 2.8 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KII87420.1 - 0.026 14.4 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Solute_trans_a PF03619.16 KII87420.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter Ostalpha mRNA_cap_enzyme PF01331.19 KII87420.1 - 0.24 11.2 2.3 2.4 7.9 1.1 3.0 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain Pkinase PF00069.25 KII87421.1 - 3.5e-69 233.1 0.0 5.2e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87421.1 - 9.4e-37 126.7 0.0 1.5e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KII87421.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Haspin_kinase PF12330.8 KII87421.1 - 0.0017 17.4 0.1 0.0028 16.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KII87421.1 - 0.0081 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII87421.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Tma16 PF11176.8 KII87422.1 - 1.6e-43 148.1 1.8 2e-43 147.8 1.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 SF3b1 PF08920.10 KII87423.1 - 1.1e-25 90.4 1.0 1.1e-25 90.4 1.0 2.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KII87423.1 - 2e-09 37.7 10.7 0.012 16.0 0.1 8.0 4 2 4 8 8 8 2 HEAT repeats HEAT PF02985.22 KII87423.1 - 2.5e-07 30.4 12.4 0.21 12.0 0.1 9.9 12 0 0 12 12 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KII87423.1 - 6.6e-07 29.8 1.4 1.1 9.9 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KII87423.1 - 8.1e-07 29.4 9.9 0.013 16.0 0.0 7.5 9 1 1 10 10 9 2 HEAT-like repeat Adaptin_N PF01602.20 KII87423.1 - 1.4e-06 27.1 1.0 0.035 12.7 0.0 3.4 3 0 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KII87423.1 - 4.3e-05 23.3 0.7 1.7 8.3 0.0 4.9 4 1 1 5 5 5 2 NUC173 domain Cnd1 PF12717.7 KII87423.1 - 7.4e-05 22.8 9.5 1.5 8.8 0.0 6.8 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KII87423.1 - 0.0002 21.2 0.6 0.37 10.7 0.0 4.8 4 2 1 5 5 5 1 UME (NUC010) domain CLASP_N PF12348.8 KII87423.1 - 0.001 18.7 1.8 1.2 8.6 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 KII87423.1 - 0.0064 16.4 1.0 0.91 9.4 0.1 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) DUF3110 PF11360.8 KII87423.1 - 0.0085 16.3 0.1 0.028 14.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) Dopey_N PF04118.14 KII87423.1 - 0.067 12.3 1.5 3.7 6.6 0.0 3.4 4 0 0 4 4 4 0 Dopey, N-terminal CTP_transf_like PF01467.26 KII87425.1 - 2.3e-17 63.5 0.0 3.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like FNIP PF05725.12 KII87426.1 - 0.071 13.3 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 FNIP Repeat F-box-like PF12937.7 KII87427.1 - 0.0015 18.4 0.4 0.004 17.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII87427.1 - 0.061 13.2 0.3 0.22 11.4 0.3 1.9 1 1 0 1 1 1 0 F-box domain BTB PF00651.31 KII87428.1 - 1.9e-05 24.8 0.0 3.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 KII87429.1 - 7.5e-26 89.4 39.7 4.3e-08 33.2 0.2 7.5 8 0 0 8 8 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KII87429.1 - 2.7e-24 84.2 42.5 5.1e-06 26.6 2.5 8.9 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII87429.1 - 1.1e-11 44.5 58.5 0.00012 22.6 2.3 8.6 10 0 0 10 10 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII87429.1 - 4.1e-07 29.8 19.9 0.014 15.4 3.0 6.8 6 0 0 6 6 6 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KII87429.1 - 3e-06 27.4 18.2 0.048 14.0 1.1 4.4 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 KII87429.1 - 2e-05 24.2 20.2 0.00032 20.4 2.7 5.7 6 0 0 6 6 6 2 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KII87429.1 - 0.0031 18.1 0.0 0.0031 18.1 0.0 7.7 4 3 4 8 8 7 2 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 KII87429.1 - 0.014 15.8 1.5 0.014 15.8 1.5 4.6 4 2 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KII87429.1 - 0.018 14.8 24.9 2.8 7.8 0.3 7.0 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KII87429.1 - 0.024 14.5 5.9 13 5.8 0.2 5.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KII87429.1 - 0.025 14.8 1.6 0.025 14.8 1.6 5.1 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KII87429.1 - 0.031 14.3 1.5 0.031 14.3 1.5 4.3 4 0 0 4 4 4 0 BED zinc finger zf_ZIC PF18366.1 KII87429.1 - 0.065 13.4 0.1 0.065 13.4 0.1 7.3 6 3 0 6 6 6 0 Zic proteins zinc finger domain zf-C2H2_9 PF16293.5 KII87429.1 - 0.11 12.3 4.4 17 5.3 0.1 4.6 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_aberr PF17017.5 KII87429.1 - 2.1 8.5 14.7 7.7 6.6 0.1 4.4 3 1 2 5 5 5 0 Aberrant zinc-finger zf-met PF12874.7 KII87429.1 - 2.8 8.4 15.7 0.4 11.1 0.9 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type SUIM_assoc PF16619.5 KII87429.1 - 2.9 8.0 8.1 0.25 11.4 2.4 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C2HE PF16278.5 KII87429.1 - 3 8.3 23.0 0.19 12.2 1.3 4.1 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger BTB PF00651.31 KII87430.1 - 0.00015 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ADH_zinc_N PF00107.26 KII87431.1 - 1.1e-07 31.8 0.9 2.4e-07 30.8 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII87431.1 - 1.5e-06 28.0 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KII87431.1 - 0.14 11.8 0.5 0.31 10.7 0.2 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SLC35F PF06027.12 KII87432.1 - 2.5e-98 329.3 19.2 3e-98 329.0 19.2 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KII87432.1 - 1.3e-07 30.9 0.6 1.3e-07 30.9 0.6 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Peptidase_M20 PF01546.28 KII87433.1 - 8.9e-07 28.8 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 KII87434.1 - 1.7e-27 96.5 0.1 2.7e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KII87434.1 - 5.1e-10 39.2 0.0 9.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KII87435.1 - 6.8e-30 104.3 0.0 9.9e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KII87435.1 - 5.9e-11 42.3 0.1 1.4e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Symplekin_C PF12295.8 KII87436.1 - 9.4e-64 214.9 0.3 2.8e-63 213.4 0.3 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KII87436.1 - 2.6e-53 181.0 0.1 9.1e-53 179.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Ribosomal_60s PF00428.19 KII87436.1 - 6.7 7.4 16.2 12 6.5 1.0 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein V-ATPase_G PF03179.15 KII87437.1 - 2.5e-34 118.0 16.7 2.8e-34 117.8 16.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KII87437.1 - 0.21 11.7 19.2 0.071 13.2 15.7 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 KII87437.1 - 0.61 10.5 16.0 1.2 9.6 16.0 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Fungal_trans PF04082.18 KII87438.1 - 8.4e-21 74.2 0.2 1.3e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII87438.1 - 1.8e-09 37.6 10.1 2.9e-09 36.9 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 KII87439.1 - 2.6e-28 98.5 10.2 3e-28 98.3 10.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 KII87439.1 - 0.022 13.2 1.1 0.027 13.0 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein EF-hand_14 PF17959.1 KII87439.1 - 0.099 13.0 0.3 0.14 12.5 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain DUF3824 PF12868.7 KII87439.1 - 0.74 10.5 4.9 1.1 9.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_S19 PF00203.21 KII87440.1 - 8.6e-31 105.7 0.1 1.3e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KII87440.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH Methyltransf_25 PF13649.6 KII87441.1 - 9.4e-07 29.5 0.0 4.1e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII87441.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87441.1 - 0.012 16.3 0.0 0.026 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1515 PF07439.11 KII87442.1 - 0.091 12.8 0.2 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) betaPIX_CC PF16523.5 KII87443.1 - 0.012 15.5 1.0 0.016 15.0 1.0 1.2 1 0 0 1 1 1 0 betaPIX coiled coil Spc7 PF08317.11 KII87443.1 - 0.25 10.2 4.9 0.31 9.9 4.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Bap31_Bap29_C PF18035.1 KII87443.1 - 1.5 8.9 6.0 2.4 8.2 6.0 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain RhoGAP PF00620.27 KII87444.1 - 2.6e-34 118.2 0.0 5e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KII87444.1 - 8.9e-28 96.3 39.1 8.8e-11 41.9 7.9 4.6 5 0 0 5 5 5 4 LIM domain BTB PF00651.31 KII87445.1 - 0.0014 18.8 0.1 0.003 17.7 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain GATA PF00320.27 KII87447.1 - 1.1e-13 50.5 1.6 1.9e-13 49.7 1.6 1.4 1 0 0 1 1 1 1 GATA zinc finger RhoGAP PF00620.27 KII87448.1 - 1.1e-11 44.8 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KII87448.1 - 2.9e-06 27.2 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KII87448.1 - 1.8e-05 24.9 0.0 4.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain CHCH PF06747.13 KII87449.1 - 9.1e-05 22.5 3.2 0.00017 21.6 3.2 1.6 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KII87449.1 - 0.00069 19.8 1.2 0.00069 19.8 1.2 1.6 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KII87449.1 - 0.014 15.7 7.2 0.027 14.7 3.2 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Filament PF00038.21 KII87450.1 - 0.0022 17.6 4.0 0.19 11.3 2.4 2.3 1 1 0 2 2 2 2 Intermediate filament protein DUF4226 PF10774.9 KII87450.1 - 0.016 15.5 0.3 0.016 15.5 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) Ribosomal_S30AE PF02482.19 KII87450.1 - 0.045 14.5 0.1 0.16 12.8 0.1 2.0 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein HDV_ag PF01517.18 KII87450.1 - 1.8 8.3 9.0 0.41 10.4 0.6 2.4 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen ArAE_2_N PF10337.9 KII87451.1 - 2.4e-54 185.1 0.1 5.6e-54 183.9 0.1 1.5 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KII87451.1 - 3.1e-31 109.0 0.0 8.4e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KII87451.1 - 1.4e-10 41.3 13.0 1.4e-10 41.3 13.0 3.6 3 0 0 3 3 3 2 Fusaric acid resistance protein-like DLH PF01738.18 KII87452.1 - 8e-20 71.3 0.0 9.2e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KII87452.1 - 8.5e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Ribosomal_L37ae PF01780.19 KII87453.1 - 2.1e-41 139.9 10.8 2.3e-41 139.7 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KII87453.1 - 0.00042 20.4 2.3 0.00058 19.9 2.3 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KII87453.1 - 0.0021 18.0 1.3 0.0035 17.3 1.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.12 KII87453.1 - 0.013 15.4 0.7 0.019 14.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) zf-FCS PF06467.14 KII87453.1 - 0.066 13.2 2.4 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 KII87453.1 - 0.097 12.1 1.8 5.7 6.5 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 KII87453.1 - 0.23 11.5 5.2 4.4 7.4 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KII87453.1 - 0.26 11.6 2.4 0.65 10.4 2.4 1.6 1 1 0 1 1 1 0 C1 domain zf-H2C2_2 PF13465.6 KII87453.1 - 0.35 11.4 5.0 2.3 8.8 0.8 2.3 1 1 1 2 2 2 0 Zinc-finger double domain UCH PF00443.29 KII87454.1 - 1.1e-70 238.1 0.0 1.6e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KII87454.1 - 4.4e-14 52.9 0.0 1.4e-13 51.2 0.0 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 KII87454.1 - 5.6e-13 49.2 0.0 2.1e-05 24.3 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 KII87454.1 - 0.041 13.6 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal DUF1712 PF08217.11 KII87455.1 - 3e-18 65.7 0.0 4.2e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) zf-CCCH PF00642.24 KII87456.1 - 2.1e-11 43.4 20.0 4.2e-05 23.3 0.8 5.1 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII87456.1 - 0.013 15.5 25.4 3.3 7.9 1.6 5.8 5 1 0 5 5 5 0 Zinc finger domain zf-CCCH_3 PF15663.5 KII87456.1 - 0.059 13.6 11.4 0.99 9.6 3.9 3.3 1 1 0 2 2 2 0 Zinc-finger containing family Defensin_beta PF00711.19 KII87456.1 - 0.069 13.2 0.4 0.069 13.2 0.4 3.2 3 0 0 3 3 3 0 Beta defensin BTV_NS2 PF04514.12 KII87456.1 - 0.17 10.6 4.5 0.25 10.1 4.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SDA1 PF05285.12 KII87456.1 - 0.32 10.4 10.7 0.42 10.0 10.7 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KII87456.1 - 0.42 10.1 11.8 0.74 9.4 11.8 1.3 1 0 0 1 1 1 0 PPP4R2 MAM33 PF02330.16 KII87456.1 - 1.2 9.1 9.5 1.8 8.4 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial glycoprotein BUD22 PF09073.10 KII87456.1 - 3 7.1 14.6 4.5 6.5 14.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KII87456.1 - 5.8 5.0 16.5 7.6 4.6 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2796 PF10986.8 KII87456.1 - 7.4 6.5 10.4 12 5.8 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RXT2_N PF08595.11 KII87456.1 - 8.7 6.3 10.4 13 5.7 10.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal AICARFT_IMPCHas PF01808.18 KII87457.1 - 8.1e-86 288.1 0.0 1e-85 287.8 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KII87457.1 - 8.3e-24 83.6 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.6 KII87458.1 - 1.9e-39 135.3 0.5 2.3e-39 135.0 0.5 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KII87458.1 - 1.1e-09 38.3 1.5 1.9e-09 37.6 1.5 1.4 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KII87458.1 - 1.6e-07 31.6 0.3 3.1e-07 30.6 0.3 1.5 1 1 0 1 1 1 1 HD domain EF-hand_4 PF12763.7 KII87458.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF383 PF04063.14 KII87460.1 - 8.7e-58 195.1 0.0 2.2e-57 193.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KII87460.1 - 2.7e-19 68.7 0.1 5.9e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Spt20 PF12090.8 KII87461.1 - 2.6e-28 99.2 0.3 1.5e-14 54.2 0.0 6.0 3 2 2 5 5 5 3 Spt20 family dsrm PF00035.26 KII87462.1 - 1.4e-07 32.1 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KII87462.1 - 1.6e-06 28.3 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII87462.1 - 0.00072 20.1 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain Pkinase PF00069.25 KII87463.1 - 1.5e-63 214.7 0.0 2e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87463.1 - 3.1e-32 111.9 0.0 4.4e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII87463.1 - 0.0016 17.4 0.1 0.0023 16.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KII87463.1 - 0.0095 15.3 0.1 0.022 14.1 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII87463.1 - 0.053 13.4 2.1 0.4 10.6 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family ParA PF10609.9 KII87464.1 - 1.2e-95 319.7 0.0 1.4e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KII87464.1 - 4.4e-09 36.5 0.0 1.2e-08 35.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KII87464.1 - 7.7e-05 22.0 1.7 0.00097 18.4 0.3 2.6 1 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KII87464.1 - 0.0002 20.9 0.0 0.53 9.7 0.0 2.5 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KII87464.1 - 0.00049 20.1 0.1 0.0039 17.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KII87464.1 - 0.0052 16.4 0.0 0.0092 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KII87464.1 - 0.0056 16.2 0.1 0.014 14.9 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KII87464.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 KII87464.1 - 0.02 14.7 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KII87464.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KII87464.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MipZ PF09140.11 KII87464.1 - 0.19 11.0 0.1 0.56 9.4 0.1 1.8 1 1 0 1 1 1 0 ATPase MipZ NACHT PF05729.12 KII87464.1 - 0.25 11.2 0.2 0.42 10.5 0.2 1.3 1 0 0 1 1 1 0 NACHT domain DLH PF01738.18 KII87465.1 - 3.4e-21 75.8 0.0 3.9e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 KII87466.1 - 1.1e-18 67.7 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family GA-like PF17573.2 KII87466.1 - 0.095 12.6 1.3 10 6.1 0.1 2.3 2 0 0 2 2 2 0 GA-like domain DLH PF01738.18 KII87467.1 - 2.5e-20 73.0 0.0 2.8e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family PGA_cap PF09587.10 KII87467.1 - 0.0058 16.1 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Abhydrolase_1 PF00561.20 KII87467.1 - 0.044 13.4 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold GA-like PF17573.2 KII87467.1 - 0.13 12.3 0.8 16 5.5 0.1 2.4 2 0 0 2 2 2 0 GA-like domain DLH PF01738.18 KII87470.1 - 3.2e-21 75.9 0.0 3.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KII87470.1 - 0.0036 17.0 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Dak1 PF02733.17 KII87471.1 - 2.3e-108 361.8 0.1 3.2e-108 361.3 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KII87471.1 - 3.4e-39 134.5 4.2 6.4e-39 133.6 4.2 1.5 1 0 0 1 1 1 1 DAK2 domain Tim44 PF04280.15 KII87472.1 - 2.4e-35 121.8 0.1 3.1e-34 118.2 0.1 2.3 2 0 0 2 2 2 1 Tim44-like domain CENP-O PF09496.10 KII87472.1 - 0.038 14.0 1.0 0.078 12.9 0.3 1.8 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component GIT_CC PF16559.5 KII87472.1 - 0.18 11.7 1.7 0.46 10.4 1.7 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Collagen_mid PF15984.5 KII87472.1 - 0.2 11.4 0.0 4 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial collagen, middle region DivIC PF04977.15 KII87472.1 - 1 9.1 3.6 2.9 7.7 3.6 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF1778 PF08681.11 KII87472.1 - 8.5 6.4 9.2 12 5.9 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1778) WD40 PF00400.32 KII87473.1 - 3.9e-11 43.3 2.3 0.023 15.5 0.0 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CPSF_A PF03178.15 KII87473.1 - 0.012 14.9 0.0 0.039 13.3 0.0 1.7 1 1 1 2 2 2 0 CPSF A subunit region Nup160 PF11715.8 KII87473.1 - 0.017 13.8 0.0 0.067 11.8 0.0 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII87473.1 - 0.052 13.8 0.0 65 3.9 0.0 3.8 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Rubella_Capsid PF05750.11 KII87473.1 - 0.44 10.1 7.0 0.74 9.4 7.0 1.2 1 0 0 1 1 1 0 Rubella capsid protein GFO_IDH_MocA PF01408.22 KII87474.1 - 3.6e-19 69.7 0.0 7.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII87474.1 - 0.006 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_47 PF01532.20 KII87475.1 - 7.9e-134 447.0 0.0 9e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 KII87476.1 - 1.4e-28 99.3 0.4 2.7e-28 98.3 0.4 1.4 1 0 0 1 1 1 1 Erv1 / Alr family DAZAP2 PF11029.8 KII87476.1 - 0.23 12.4 6.5 0.26 12.2 6.0 1.5 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Zip PF02535.22 KII87477.1 - 6.8e-62 209.6 10.7 7.7e-62 209.4 10.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-HIT PF04438.16 KII87478.1 - 9.6e-09 35.0 11.1 2e-08 33.9 11.1 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KII87478.1 - 0.27 11.3 7.9 0.45 10.7 7.1 1.8 1 1 1 2 2 2 0 MYND finger DEAD PF00270.29 KII87479.1 - 2.3e-38 131.7 0.1 3.5e-38 131.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII87479.1 - 2e-28 98.9 0.0 1.1e-27 96.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII87479.1 - 0.00023 21.2 0.0 0.00072 19.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KII87479.1 - 0.055 12.8 0.8 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PRR20 PF15708.5 KII87479.1 - 2 8.2 6.1 1.2 9.0 0.4 2.2 2 0 0 2 2 2 0 Proline-rich protein family 20 FGGY_C PF02782.16 KII87480.1 - 4.5e-60 202.8 2.6 7e-60 202.2 2.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KII87480.1 - 2.8e-58 197.4 0.0 7e-57 192.8 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MCR_C PF04609.12 KII87480.1 - 0.12 11.4 0.0 0.96 8.5 0.0 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Glyco_hydro_47 PF01532.20 KII87481.1 - 9.2e-132 440.2 0.0 1.1e-131 439.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3168 PF11367.8 KII87481.1 - 0.042 14.0 0.0 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) ANTH PF07651.16 KII87482.1 - 1e-50 172.3 0.0 1.5e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KII87482.1 - 0.00044 20.3 0.0 0.00088 19.3 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KII87482.1 - 0.0052 17.2 30.1 0.0052 17.2 30.1 9.2 1 1 4 5 5 5 3 Domain of unknown function (DUF1720) SHNi-TPR PF10516.9 KII87483.1 - 1.6e-14 53.0 0.3 5.3e-13 48.2 0.0 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KII87483.1 - 2.1e-13 50.3 6.4 1.8e-06 28.1 0.7 3.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KII87483.1 - 7.5e-06 25.6 5.2 0.043 13.7 1.6 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII87483.1 - 7.9e-06 25.6 5.0 0.24 11.6 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII87483.1 - 1.7e-05 24.7 1.3 1.1 9.7 0.4 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KII87483.1 - 0.00071 19.4 0.3 0.48 10.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII87483.1 - 0.019 15.4 6.9 1.7 9.2 0.0 4.1 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII87483.1 - 0.021 14.8 2.1 4.1 7.7 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KII87483.1 - 0.022 14.8 2.4 0.12 12.5 0.8 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CreD PF06123.12 KII87483.1 - 0.18 10.6 0.5 9.6 4.9 0.0 2.1 2 0 0 2 2 2 0 Inner membrane protein CreD TPR_16 PF13432.6 KII87483.1 - 0.18 12.5 11.5 1.8 9.3 3.3 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII87483.1 - 1.6 8.5 9.7 6.8 6.5 0.1 3.7 4 1 0 4 4 4 0 TPR repeat TPR_3 PF07720.12 KII87483.1 - 2 8.5 6.3 0.71 9.9 1.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.22 KII87484.1 - 2.9e-11 42.6 5.0 7.3e-10 37.9 3.2 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KII87484.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Paf1 PF03985.13 KII87485.1 - 2e-72 244.6 0.0 2.3e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Paf1 Ribosomal_S4e PF00900.20 KII87486.1 - 7.9e-36 121.8 0.1 2.3e-35 120.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KII87486.1 - 5.6e-25 86.7 0.1 9.5e-25 86.0 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KII87486.1 - 1.7e-21 76.0 5.2 8.8e-21 73.7 5.8 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KII87486.1 - 1.2e-07 31.3 0.1 2.3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KII87486.1 - 2.2e-05 24.2 3.3 7e-05 22.6 3.3 2.0 1 0 0 1 1 1 1 KOW motif TPT PF03151.16 KII87487.1 - 7.4e-55 186.3 19.0 9e-55 186.1 19.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KII87487.1 - 3.3e-11 43.0 19.1 4.2e-11 42.6 19.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KII87487.1 - 1.9e-09 37.8 32.5 1.5e-06 28.4 12.6 3.0 2 1 0 2 2 2 2 EamA-like transporter family TrkH PF02386.16 KII87488.1 - 2.1e-97 326.7 10.0 1.7e-96 323.6 1.2 2.1 2 0 0 2 2 2 2 Cation transport protein DRMBL PF07522.14 KII87489.1 - 4.1e-29 101.0 0.0 7.8e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KII87489.1 - 7.5e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KII87489.1 - 0.017 15.1 0.5 0.2 11.7 0.1 2.5 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily HECT PF00632.25 KII87490.1 - 3.6e-74 250.0 0.0 5.2e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Aminotran_3 PF00202.21 KII87490.1 - 6.5e-70 235.8 0.0 9.9e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Arm PF00514.23 KII87490.1 - 0.00053 19.9 1.5 0.11 12.5 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat GM_CSF PF01109.17 KII87490.1 - 0.093 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DUF4551 PF15087.6 KII87490.1 - 0.67 8.7 13.6 1.4 7.6 13.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) UIM PF02809.20 KII87490.1 - 1 9.4 3.8 4.1 7.5 3.8 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif GST_N PF02798.20 KII87491.1 - 1.5e-15 57.2 0.0 3.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KII87491.1 - 3.6e-13 49.7 0.0 7.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII87491.1 - 5.1e-09 36.3 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KII87491.1 - 0.0075 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII87491.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KII87491.1 - 0.12 13.1 0.0 0.68 10.7 0.0 2.2 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain DNA_pol_alpha_N PF12254.8 KII87492.1 - 2.9e-06 27.2 3.2 7.8e-06 25.9 3.2 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CRAL_TRIO PF00650.20 KII87493.1 - 2e-23 82.9 0.0 2.7e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII87493.1 - 0.0011 19.1 0.3 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain HABP4_PAI-RBP1 PF04774.15 KII87493.1 - 3.6 8.5 12.4 8.4 7.3 12.4 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family ZZ PF00569.17 KII87495.1 - 4e-19 68.2 59.9 1.4e-07 31.2 10.3 6.3 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.24 KII87495.1 - 2e-05 24.4 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 KII87495.1 - 4.5e-05 23.7 48.9 0.17 12.2 8.4 6.2 6 0 0 6 6 6 4 C1 domain Yippee-Mis18 PF03226.14 KII87495.1 - 0.28 11.4 0.1 0.28 11.4 0.1 4.2 2 1 2 4 4 4 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.25 KII87498.1 - 5.3e-12 45.7 0.0 0.00013 21.4 0.0 3.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII87498.1 - 1.6e-06 27.6 0.5 0.038 13.3 0.1 2.7 2 2 0 2 2 2 2 Protein tyrosine kinase Tmemb_14 PF03647.13 KII87500.1 - 5.1e-18 65.6 6.9 6e-18 65.4 6.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KII87500.1 - 0.16 12.2 2.4 1.4 9.2 2.4 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 NAD_binding_4 PF07993.12 KII87501.1 - 2.7e-37 128.3 0.0 4.3e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII87501.1 - 3.5e-27 95.1 0.0 1.2e-26 93.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII87501.1 - 3.5e-07 29.9 0.0 6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII87501.1 - 0.0001 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KII87501.1 - 0.0019 18.5 0.3 0.01 16.2 0.3 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KII87501.1 - 0.034 14.1 0.0 0.23 11.4 0.0 2.2 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KII87501.1 - 0.042 14.3 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DSPc PF00782.20 KII87502.1 - 8.5e-28 96.8 0.0 1.1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KII87502.1 - 0.00053 19.7 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KII87502.1 - 0.00098 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KII87502.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Myotub-related PF06602.14 KII87502.1 - 0.2 10.6 0.1 0.3 10.0 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Med4 PF10018.9 KII87503.1 - 3.4e-18 66.0 0.0 5.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Seryl_tRNA_N PF02403.22 KII87503.1 - 0.1 12.9 1.6 0.24 11.7 1.6 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Voltage_CLC PF00654.20 KII87504.1 - 6.2e-83 279.0 26.0 6.2e-83 279.0 26.0 2.1 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KII87504.1 - 4.3e-08 33.5 0.7 0.011 16.1 0.1 2.9 2 0 0 2 2 2 2 CBS domain PvlArgDC PF01862.16 KII87505.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) FAM150 PF15129.6 KII87505.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM150 family MMS19_C PF12460.8 KII87506.1 - 1e-125 420.2 1.2 3.4e-125 418.5 0.3 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KII87506.1 - 4.4e-90 301.8 0.3 2.4e-86 289.5 0.0 3.6 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KII87506.1 - 1.9e-05 25.1 7.7 0.32 11.5 0.2 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 KII87506.1 - 0.0025 18.2 4.9 1.1 9.7 0.1 5.0 5 1 1 6 6 6 2 HEAT repeats DUF3385 PF11865.8 KII87506.1 - 0.0099 15.8 0.0 7.7 6.4 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) Baculo_gp41 PF04700.12 KII87506.1 - 0.047 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Adaptin_N PF01602.20 KII87506.1 - 0.11 11.0 0.0 2.6 6.5 0.0 2.5 1 1 1 2 2 2 0 Adaptin N terminal region Methyltransf_28 PF02636.17 KII87507.1 - 2e-38 132.5 0.0 2.7e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KII87507.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KII87507.1 - 0.023 15.4 0.0 0.12 13.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MBOAT_2 PF13813.6 KII87509.1 - 1.6e-22 79.5 2.0 5.7e-22 77.8 2.0 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_25 PF13649.6 KII87510.1 - 7.4e-12 45.8 0.1 1.9e-11 44.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87510.1 - 9.8e-12 45.4 0.1 2.3e-11 44.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII87510.1 - 1e-09 38.4 0.0 1.4e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII87510.1 - 3.9e-06 27.5 0.0 6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII87510.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KII87510.1 - 0.0037 16.9 0.0 0.0074 15.9 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 KII87510.1 - 0.032 13.6 0.2 0.4 10.0 0.2 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PQ-loop PF04193.14 KII87511.1 - 1.3e-32 111.4 7.0 1.3e-17 63.3 1.4 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KII87511.1 - 7.4e-05 23.6 0.6 0.088 13.6 0.0 2.6 2 1 1 3 3 3 2 ER lumen protein retaining receptor MtN3_slv PF03083.16 KII87511.1 - 0.00022 21.2 6.8 0.035 14.1 0.5 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 KII87511.1 - 0.18 11.9 9.7 2.2 8.4 0.5 2.5 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PQ-loop PF04193.14 KII87512.1 - 3.7e-29 100.3 8.7 4.5e-17 61.6 1.6 2.6 2 1 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KII87512.1 - 0.0058 17.5 3.6 0.097 13.5 0.4 2.5 2 1 0 2 2 2 1 ER lumen protein retaining receptor MtN3_slv PF03083.16 KII87512.1 - 0.069 13.2 7.6 0.38 10.8 0.9 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Peptidase_U4 PF03419.13 KII87512.1 - 0.35 10.1 10.7 3.2 7.0 10.7 2.0 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Kei1 PF08552.11 KII87513.1 - 7.1e-57 192.4 8.5 8.9e-57 192.1 8.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.18 KII87514.1 - 2.4e-53 180.2 0.3 2.9e-53 179.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelR PF01641.18 KII87515.1 - 2.5e-52 176.1 0.1 2.9e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 KII87515.1 - 0.0088 16.1 1.7 0.39 10.9 0.3 2.8 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_10 PF10058.9 KII87515.1 - 0.016 14.9 0.1 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein RIG-I_C-RD PF11648.8 KII87515.1 - 0.047 13.9 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 C-terminal domain of RIG-I zinc_ribbon_2 PF13240.6 KII87515.1 - 0.054 13.2 1.5 7.7 6.4 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.14 KII87515.1 - 0.055 13.8 0.4 0.99 9.8 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme MCM_OB PF17207.3 KII87515.1 - 0.079 12.8 0.1 0.13 12.1 0.0 1.4 2 0 0 2 2 2 0 MCM OB domain TackOD1 PF18551.1 KII87515.1 - 0.085 12.5 0.5 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Yippee-Mis18 PF03226.14 KII87515.1 - 0.088 13.0 0.5 0.29 11.4 0.5 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KII87515.1 - 0.098 12.7 3.3 0.5 10.4 2.2 2.2 1 1 2 3 3 3 0 Double zinc ribbon zf-ACC PF17848.1 KII87515.1 - 0.62 10.2 2.4 5.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KII87515.1 - 2 7.9 6.9 13 5.4 0.1 3.1 4 0 0 4 4 4 0 zinc-ribbon domain Tropomyosin_1 PF12718.7 KII87516.1 - 6.2e-49 165.8 31.5 7.2e-49 165.6 31.5 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KII87516.1 - 7.2e-12 45.2 30.4 7.7e-06 25.5 5.9 3.0 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.6 KII87516.1 - 0.0011 18.3 31.3 0.021 14.2 9.6 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KII87516.1 - 0.004 17.2 7.6 0.004 17.2 7.6 2.9 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 KII87516.1 - 0.0052 17.2 13.5 0.0052 17.2 13.5 2.2 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 KII87516.1 - 0.011 15.7 3.4 0.011 15.7 3.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Transketolase_N PF00456.21 KII87516.1 - 0.011 14.7 6.5 0.015 14.3 6.5 1.0 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Jnk-SapK_ap_N PF09744.9 KII87516.1 - 0.013 15.8 18.5 0.013 15.8 18.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KELK PF15796.5 KII87516.1 - 0.013 15.9 4.1 0.013 15.9 4.1 3.7 2 2 1 3 3 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DHR10 PF18595.1 KII87516.1 - 0.017 15.2 33.6 0.21 11.7 13.0 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KII87516.1 - 0.034 14.5 22.9 0.065 13.6 7.3 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Laminin_II PF06009.12 KII87516.1 - 0.035 14.1 16.0 0.69 9.9 9.2 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF724 PF05266.14 KII87516.1 - 0.038 13.8 27.3 0.64 9.8 11.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KII87516.1 - 0.041 14.3 32.7 0.47 10.9 12.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 KII87516.1 - 0.043 13.1 26.5 0.088 12.1 12.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 KII87516.1 - 0.055 13.6 27.8 0.45 10.6 7.6 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase T3SSipB PF16535.5 KII87516.1 - 0.07 13.6 22.7 7.4 7.0 22.7 2.3 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF4407 PF14362.6 KII87516.1 - 0.073 12.4 20.3 0.097 12.0 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 KII87516.1 - 0.099 12.9 30.2 0.12 12.5 12.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FliD_C PF07195.12 KII87516.1 - 0.11 11.9 14.5 0.28 10.6 4.7 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ADIP PF11559.8 KII87516.1 - 0.13 12.4 25.5 2.3 8.3 14.1 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 KII87516.1 - 0.14 12.6 25.0 0.74 10.2 24.7 1.9 1 1 0 1 1 1 0 Fez1 HMMR_N PF15905.5 KII87516.1 - 0.16 11.4 27.2 0.24 10.8 27.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 KII87516.1 - 0.2 11.7 33.5 2.5 8.2 16.4 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Gp58 PF07902.11 KII87516.1 - 0.21 9.9 6.6 0.5 8.6 6.6 1.6 1 1 0 1 1 1 0 gp58-like protein DUF5082 PF16888.5 KII87516.1 - 0.22 11.8 21.9 0.42 10.9 6.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) CLZ PF16526.5 KII87516.1 - 0.23 11.8 23.3 1.1 9.6 4.3 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BORCS7 PF16088.5 KII87516.1 - 0.23 11.7 7.0 1.3 9.3 0.3 3.2 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 7 ERM PF00769.19 KII87516.1 - 0.31 10.8 32.7 0.11 12.2 29.0 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 KII87516.1 - 0.34 8.4 27.4 0.44 8.0 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0242 PF06785.11 KII87516.1 - 0.35 11.0 29.5 0.12 12.5 12.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 KII87516.1 - 0.43 10.9 19.1 1.6 9.1 2.7 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein APG6_N PF17675.1 KII87516.1 - 0.44 11.1 37.6 0.26 11.8 22.4 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region EzrA PF06160.12 KII87516.1 - 0.56 8.3 26.7 0.033 12.4 8.5 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4201 PF13870.6 KII87516.1 - 0.64 9.7 26.0 0.65 9.7 8.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 KII87516.1 - 0.77 9.9 17.7 1.5 9.0 5.1 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4061 PF13270.6 KII87516.1 - 0.91 9.9 18.3 2.8 8.3 3.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4061) HGD-D PF06050.13 KII87516.1 - 1.1 9.0 7.3 0.12 12.1 2.5 1.7 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component KLRAQ PF10205.9 KII87516.1 - 1.3 9.3 18.5 0.041 14.1 3.1 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein ArAE_2_N PF10337.9 KII87516.1 - 1.8 7.5 6.6 1.9 7.4 6.6 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Spc7 PF08317.11 KII87516.1 - 1.9 7.3 31.3 0.21 10.4 18.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein SHE3 PF17078.5 KII87516.1 - 2.6 7.7 24.5 0.77 9.4 10.6 2.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Tup_N PF08581.10 KII87516.1 - 2.9 8.3 24.2 0.15 12.4 6.0 2.6 1 1 2 3 3 3 0 Tup N-terminal HHV-5_US34A PF17087.5 KII87516.1 - 3.3 7.9 8.9 0.3 11.2 1.6 2.6 2 1 1 3 3 2 0 Herpesvirus US34A protein family Fzo_mitofusin PF04799.13 KII87516.1 - 3.5 7.2 13.0 0.33 10.5 2.7 2.2 1 1 0 2 2 2 0 fzo-like conserved region TMF_TATA_bd PF12325.8 KII87516.1 - 4.5 7.5 25.9 1.3 9.3 11.7 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 KII87516.1 - 5.9 4.7 9.5 6.2 4.6 9.5 1.2 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.22 KII87516.1 - 6 7.1 27.3 1.1 9.5 16.8 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 KII87516.1 - 6.5 6.9 23.3 30 4.8 6.7 3.8 1 1 1 3 3 3 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 KII87516.1 - 6.9 6.7 34.8 0.88 9.6 16.8 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 KII87516.1 - 7 7.0 33.2 3 8.2 14.2 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 KII87516.1 - 7.2 5.0 7.3 7.3 5.0 7.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF812 PF05667.11 KII87516.1 - 7.4 5.3 27.4 10 4.9 27.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4164 PF13747.6 KII87516.1 - 8.1 6.8 26.4 6.4 7.1 10.8 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.13 KII87516.1 - 8.3 7.2 19.4 23 5.8 4.5 3.1 1 1 1 2 2 2 0 Occludin homology domain LMBR1 PF04791.16 KII87516.1 - 8.8 5.1 14.3 13 4.6 14.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2408 PF10303.9 KII87517.1 - 4.3e-62 208.6 5.0 3.1e-43 147.6 0.2 5.0 4 1 0 5 5 5 4 Protein of unknown function (DUF2408) FUSC PF04632.12 KII87517.1 - 0.03 12.9 1.4 0.043 12.3 1.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KII87517.1 - 0.095 12.7 3.1 2.1 8.4 0.1 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KII87517.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.8 1 1 0 1 1 1 0 Fez1 Snapin_Pallidin PF14712.6 KII87517.1 - 0.16 12.4 8.8 3.8 8.0 0.0 5.0 5 1 0 5 5 5 0 Snapin/Pallidin MscS_porin PF12795.7 KII87517.1 - 0.17 11.4 2.0 4.3 6.8 0.2 2.9 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain ZapA PF05164.13 KII87517.1 - 0.26 11.7 4.9 0.66 10.4 0.0 3.0 3 0 0 3 3 3 0 Cell division protein ZapA Med9 PF07544.13 KII87517.1 - 0.36 10.9 3.4 1.4 9.1 0.2 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.12 KII87517.1 - 0.81 9.7 2.7 30 4.6 0.3 3.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KII87517.1 - 3.3 7.9 6.4 9.8 6.3 2.3 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ATP-synt_ab PF00006.25 KII87518.1 - 8.6e-73 244.5 0.0 1.3e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KII87518.1 - 6e-42 142.9 0.0 9.6e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KII87518.1 - 1.8e-17 63.6 1.2 4.1e-17 62.5 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ribosomal_L21p PF00829.21 KII87519.1 - 7.8e-24 83.9 0.1 9.6e-24 83.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SPOR PF05036.13 KII87519.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Sporulation related domain FF PF01846.19 KII87520.1 - 1.7e-36 124.2 6.5 6.7e-13 48.6 0.0 6.0 5 1 1 6 6 6 5 FF domain WW PF00397.26 KII87520.1 - 5.7e-13 48.7 17.4 2.4e-06 27.5 4.9 2.7 2 0 0 2 2 2 2 WW domain SelB-wing_2 PF09106.11 KII87520.1 - 0.057 13.6 4.1 0.052 13.8 1.0 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Brix PF04427.18 KII87521.1 - 1.6e-24 87.1 0.0 2.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain EMP24_GP25L PF01105.24 KII87522.1 - 2.3e-49 167.8 0.1 2.6e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MCU PF04678.13 KII87522.1 - 0.046 13.8 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PAP_RNA-bind PF04926.15 KII87522.1 - 0.051 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain ADH_zinc_N PF00107.26 KII87523.1 - 6.8e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII87523.1 - 0.0019 18.0 0.0 0.0062 16.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII87523.1 - 0.0089 17.1 0.0 0.018 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KII87523.1 - 0.011 15.6 0.2 0.022 14.7 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 KII87523.1 - 0.035 13.5 0.2 0.076 12.5 0.1 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 KII87523.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DDE_3 PF13358.6 KII87524.1 - 1.1e-09 38.2 0.2 0.0022 17.8 0.0 3.6 3 0 0 3 3 3 3 DDE superfamily endonuclease KDZ PF18758.1 KII87525.1 - 3.4e-62 210.0 0.0 5.6e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII87525.1 - 4.5e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII87525.1 - 1.8e-06 28.1 0.1 4.8e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF1690 PF07956.11 KII87525.1 - 4.1 7.8 9.4 3.1 8.2 2.9 2.5 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) CDC45 PF02724.14 KII87528.1 - 2.5 6.3 13.0 2.8 6.1 13.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Vg_Tdu PF07545.14 KII87528.1 - 8 6.3 8.5 25 4.7 0.7 2.7 2 0 0 2 2 2 0 Vestigial/Tondu family Cauli_VI PF01693.16 KII87533.1 - 3.3e-05 24.1 2.5 8.3e-05 22.8 0.0 2.5 3 0 0 3 3 3 1 Caulimovirus viroplasmin Retinal PF15449.6 KII87533.1 - 0.00011 20.2 9.4 0.00011 20.2 9.4 1.0 1 0 0 1 1 1 1 Retinal protein NinF PF05810.12 KII87533.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NinF protein KDZ PF18758.1 KII87536.1 - 4.7e-55 186.6 0.0 7.6e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII87536.1 - 2.4e-41 140.2 0.1 5.8e-41 139.0 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII87536.1 - 0.00058 20.0 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-UBR PF02207.20 KII87536.1 - 0.021 15.0 5.9 0.065 13.4 5.9 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 KII87536.1 - 1.9 8.7 9.9 0.44 10.7 6.1 2.0 2 0 0 2 2 2 0 B-box zinc finger Tub_N PF16322.5 KII87537.1 - 0.01 16.3 0.1 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 Tubby N-terminal GPHH PF16905.5 KII87539.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated CxC2 PF18803.1 KII87541.1 - 8.4e-39 132.0 0.0 1.3e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII87541.1 - 8.2e-05 22.7 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII87542.1 - 1.9e-55 187.9 0.0 2.9e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase GST_C_2 PF13410.6 KII87542.1 - 0.011 15.7 0.1 0.065 13.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Retrotran_gag_2 PF14223.6 KII87544.1 - 1.6e-15 57.0 0.0 2.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII87544.1 - 0.0081 16.2 4.8 0.013 15.5 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KII87544.1 - 0.29 11.0 3.9 0.49 10.3 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 KII87545.1 - 3.9e-17 62.2 0.0 5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_29 PF13551.6 KII87547.1 - 1.3e-06 28.3 0.1 1.9e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.6 KII87547.1 - 1.3e-06 28.1 0.1 1.9e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 KII87547.1 - 1.4e-06 28.3 0.9 1.8e-06 27.9 0.9 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KII87547.1 - 5.6e-06 26.0 0.5 7.6e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 KII87547.1 - 7.5e-06 26.5 0.1 0.028 15.0 0.2 2.1 2 0 0 2 2 2 2 Homeodomain-like domain HTH_7 PF02796.15 KII87547.1 - 0.00094 19.2 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Sigma70_r4 PF04545.16 KII87547.1 - 0.0012 18.3 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 KII87547.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.19 KII87547.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB LacI PF00356.21 KII87547.1 - 0.044 13.6 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_11 PF08279.12 KII87547.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_22 PF13309.6 KII87547.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 KII87547.1 - 0.083 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Retrotran_gag_2 PF14223.6 KII87549.1 - 6.7e-16 58.2 0.0 8.2e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 KII87549.1 - 0.045 14.0 0.0 0.076 13.3 0.0 1.4 1 1 0 1 1 1 0 Retrotransposon gag protein PUD PF03714.14 KII87550.1 - 0.24 12.3 1.4 0.45 11.4 1.4 1.4 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Zn_clus PF00172.18 KII87551.1 - 0.086 13.0 8.2 0.72 10.0 3.1 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.14 KII87553.1 - 5.6e-13 48.5 0.0 5.8e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CxC2 PF18803.1 KII87556.1 - 8.8e-22 77.3 0.1 2.1e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 KII87556.1 - 2.3e-19 69.9 0.3 6e-16 58.7 0.1 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII87556.1 - 0.0029 17.7 0.2 0.0066 16.6 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases WW PF00397.26 KII87562.1 - 8.6e-06 25.7 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 WW domain Frag1 PF10277.9 KII87562.1 - 0.0078 15.8 4.9 0.024 14.2 4.8 1.8 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family RseC_MucC PF04246.12 KII87562.1 - 0.45 10.5 5.8 0.83 9.6 3.7 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC WW PF00397.26 KII87564.1 - 0.0004 20.4 0.6 0.0004 20.4 0.6 2.6 2 0 0 2 2 2 1 WW domain NDUFA12 PF05071.16 KII87565.1 - 3.4e-10 40.6 3.1 5.4e-10 40.0 3.1 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UPF0449 PF15136.6 KII87565.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Meth_synt_2 PF01717.18 KII87566.1 - 6.5e-08 32.2 0.1 0.00083 18.7 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Rpn3_C PF08375.11 KII87567.1 - 1.9e-21 76.2 0.2 7.6e-21 74.3 0.2 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KII87567.1 - 1e-20 74.2 0.0 4.3e-20 72.2 0.0 2.1 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KII87567.1 - 0.006 16.6 4.1 0.0061 16.6 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 KII87567.1 - 0.21 11.6 1.4 0.66 10.0 1.4 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 TPR_14 PF13428.6 KII87567.1 - 0.38 11.7 2.3 9.1 7.4 0.4 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII87567.1 - 0.45 11.2 9.8 1.7 9.3 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KII87568.1 - 6.2e-31 107.6 33.8 6.2e-31 107.6 33.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KII87568.1 - 9.3e-06 25.2 6.7 9.3e-06 25.2 6.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUP PF00674.18 KII87568.1 - 0.087 13.0 1.3 0.3 11.2 1.3 1.9 1 0 0 1 1 1 0 DUP family PHD PF00628.29 KII87569.1 - 9e-09 35.1 0.3 1.6e-08 34.3 0.3 1.4 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.24 KII87569.1 - 7.4e-08 32.2 0.1 1.4e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PhnA_Zn_Ribbon PF08274.12 KII87569.1 - 0.051 13.5 1.1 0.1 12.6 1.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon PHD_4 PF16866.5 KII87569.1 - 0.14 12.2 0.2 0.28 11.3 0.2 1.5 1 0 0 1 1 1 0 PHD-finger APC_r PF05923.12 KII87569.1 - 0.14 11.9 4.5 0.36 10.6 4.5 1.7 1 0 0 1 1 1 0 APC repeat WW PF00397.26 KII87570.1 - 0.00028 20.9 6.0 0.00028 20.9 0.2 2.4 2 0 0 2 2 2 1 WW domain Sec20 PF03908.13 KII87571.1 - 3.5e-18 65.3 0.9 3.5e-18 65.3 0.9 2.2 2 1 1 3 3 3 1 Sec20 Apq12 PF12716.7 KII87571.1 - 0.36 10.8 4.8 0.85 9.6 4.8 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Chromo PF00385.24 KII87572.1 - 3.7e-08 33.1 0.4 6e-08 32.5 0.4 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KII87572.1 - 5.6e-06 26.2 6.5 1.3e-05 25.0 6.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KII87572.1 - 0.46 10.1 5.6 0.87 9.2 5.6 1.4 1 0 0 1 1 1 0 PHD-finger Ribophorin_II PF05817.14 KII87573.1 - 8.9e-37 126.9 0.0 1e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.20 KII87574.1 - 5e-129 431.2 0.0 5.7e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KII87574.1 - 0.13 11.7 3.2 5.8 6.3 0.0 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 F-box-like PF12937.7 KII87575.1 - 0.021 14.7 0.0 0.072 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like AhpC-TSA PF00578.21 KII87575.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 1 0 0 1 1 1 0 AhpC/TSA family RNA_POL_M_15KD PF02150.16 KII87575.1 - 0.49 10.3 2.3 8.5 6.4 0.0 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Syntaxin-6_N PF09177.11 KII87576.1 - 1.6e-26 92.7 4.2 8.9e-26 90.3 0.4 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KII87576.1 - 2.3e-07 30.7 0.6 5.8e-07 29.4 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 KII87576.1 - 0.0023 17.7 0.0 0.0034 17.2 0.0 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 HMMR_N PF15905.5 KII87576.1 - 0.0029 17.1 3.8 0.015 14.8 0.2 2.1 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal FliJ PF02050.16 KII87576.1 - 0.0032 17.7 3.3 0.75 10.0 0.0 2.9 2 2 1 3 3 3 2 Flagellar FliJ protein DUF1640 PF07798.11 KII87576.1 - 0.0085 16.2 3.1 0.78 9.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) DUF3040 PF11239.8 KII87576.1 - 0.023 14.9 0.2 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Rx_N PF18052.1 KII87576.1 - 0.073 13.4 2.5 2 8.8 0.1 3.1 2 1 1 3 3 3 0 Rx N-terminal domain Spc7 PF08317.11 KII87576.1 - 0.086 11.7 6.2 0.28 10.0 0.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 KII87576.1 - 0.093 12.3 5.0 0.53 9.8 0.7 2.4 2 0 0 2 2 2 0 PspA/IM30 family Laminin_I PF06008.14 KII87576.1 - 0.1 12.3 3.0 1.1 8.9 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain I THOC7 PF05615.13 KII87576.1 - 0.12 12.6 1.6 0.62 10.3 0.4 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 Prominin PF05478.11 KII87576.1 - 0.15 10.0 0.2 2.6 5.9 0.0 2.0 2 0 0 2 2 2 0 Prominin HisKA_3 PF07730.13 KII87576.1 - 0.22 12.1 0.2 0.22 12.1 0.2 2.9 2 1 0 2 2 2 0 Histidine kinase SlyX PF04102.12 KII87576.1 - 0.25 12.0 8.2 16 6.2 1.3 4.0 2 2 2 4 4 4 0 SlyX XhlA PF10779.9 KII87576.1 - 0.33 11.2 3.9 9.1 6.6 0.9 2.8 2 1 1 3 3 3 0 Haemolysin XhlA Seryl_tRNA_N PF02403.22 KII87576.1 - 0.6 10.4 4.5 1.4 9.2 0.5 2.6 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 KII87576.1 - 0.85 10.0 5.6 5.7 7.4 0.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 KII87576.1 - 1 9.6 4.0 2.4 8.4 0.2 3.1 3 2 0 3 3 3 0 Centrosomin N-terminal motif 1 Lebercilin PF15619.6 KII87576.1 - 1.2 8.8 7.1 0.96 9.1 0.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease BRE1 PF08647.11 KII87576.1 - 1.8 8.7 5.9 2.3 8.4 0.1 2.9 3 2 0 3 3 3 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 KII87576.1 - 1.8 9.1 8.3 1.2 9.7 0.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 KII87576.1 - 3.2 8.0 7.8 0.28 11.4 1.0 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Sec23_trunk PF04811.15 KII87577.1 - 1.9e-71 240.5 0.0 3e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KII87577.1 - 7.2e-22 77.2 0.3 1.6e-21 76.0 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KII87577.1 - 7.3e-17 61.9 0.0 1.7e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KII87577.1 - 2.5e-15 56.3 6.3 4.6e-15 55.4 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KII87577.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KII87577.1 - 0.0028 17.0 0.8 0.0062 15.9 0.8 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain WW PF00397.26 KII87577.1 - 0.0069 16.5 0.9 0.0069 16.5 0.9 1.9 2 0 0 2 2 2 1 WW domain Sec23_trunk PF04811.15 KII87578.1 - 1.4e-68 231.1 0.0 2.6e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KII87578.1 - 2e-23 82.2 0.1 4.4e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KII87578.1 - 6.4e-18 65.3 0.1 1.7e-17 63.9 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KII87578.1 - 5.1e-16 58.4 7.1 1.1e-15 57.3 7.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KII87578.1 - 4.7e-09 36.0 0.0 9.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KII87578.1 - 0.017 14.5 0.6 0.034 13.5 0.6 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_S5 PF00333.20 KII87579.1 - 1.1e-20 73.4 0.1 4.5e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KII87579.1 - 1.6e-18 65.9 0.1 3e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Methyltransf_19 PF04672.12 KII87579.1 - 0.032 13.7 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase PITH PF06201.13 KII87580.1 - 2.2e-38 131.9 0.0 2.7e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain ELYS PF13934.6 KII87581.1 - 2e-39 135.9 0.1 2.4e-39 135.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly MFS_1 PF07690.16 KII87582.1 - 2.3e-17 63.0 47.9 4.7e-12 45.5 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 KII87583.1 - 2.7e-85 283.4 0.0 8.3e-42 142.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII87583.1 - 2.5e-21 75.2 0.2 1.2e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 KII87583.1 - 1.2e-13 51.2 0.0 1.4e-07 31.6 0.0 4.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KII87583.1 - 2.9e-13 49.9 0.0 0.00022 21.0 0.0 3.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KII87583.1 - 1.8e-12 48.0 3.2 5e-06 27.0 0.1 4.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 KII87583.1 - 3.6e-12 46.7 0.0 1.9e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KII87583.1 - 1.9e-08 34.5 0.0 0.00026 21.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII87583.1 - 6e-08 33.1 0.2 0.0034 17.6 0.0 4.3 2 2 1 4 4 4 1 AAA domain TIP49 PF06068.13 KII87583.1 - 8.1e-08 31.8 0.0 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KII87583.1 - 1.4e-07 31.4 0.0 0.0006 19.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KII87583.1 - 8.1e-06 25.9 0.0 0.049 13.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KII87583.1 - 1.6e-05 24.9 0.0 0.043 13.8 0.0 2.5 2 1 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KII87583.1 - 1.8e-05 24.4 3.3 1.6 8.2 0.1 4.3 2 2 2 4 4 4 2 AAA domain AAA_28 PF13521.6 KII87583.1 - 0.00011 22.5 0.0 0.035 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KII87583.1 - 0.00012 22.4 0.0 0.045 14.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KII87583.1 - 0.00023 20.6 0.3 0.23 10.8 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KII87583.1 - 0.00029 20.2 0.0 0.037 13.3 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_11 PF13086.6 KII87583.1 - 0.00077 19.3 0.0 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KII87583.1 - 0.00095 19.7 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII87583.1 - 0.0013 18.2 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KII87583.1 - 0.0014 18.6 0.1 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Rad17 PF03215.15 KII87583.1 - 0.003 17.5 0.3 1 9.2 0.0 3.3 2 2 1 3 3 3 1 Rad17 P-loop domain DAP3 PF10236.9 KII87583.1 - 0.0036 16.5 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 KII87583.1 - 0.0064 16.2 0.0 0.095 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KII87583.1 - 0.008 16.0 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KII87583.1 - 0.0092 15.7 0.0 1.1 9.0 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 KII87583.1 - 0.012 15.3 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KII87583.1 - 0.014 14.8 0.1 0.63 9.5 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.18 KII87583.1 - 0.026 14.3 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 KII87583.1 - 0.03 13.4 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 KII87583.1 - 0.054 12.8 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 KII87583.1 - 0.061 13.8 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF433 PF04255.14 KII87583.1 - 0.066 13.1 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF433) AAA_19 PF13245.6 KII87583.1 - 0.11 12.9 0.1 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KII87583.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 KII87583.1 - 0.14 11.3 0.0 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Hydin_ADK PF17213.3 KII87583.1 - 0.14 12.4 0.6 0.34 11.2 0.1 1.9 2 0 0 2 2 1 0 Hydin Adenylate kinase-like domain DUF815 PF05673.13 KII87583.1 - 0.19 10.9 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KII87583.1 - 0.19 11.6 0.0 32 4.3 0.0 3.0 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 KII87584.1 - 1.1e-48 165.9 0.0 1.4e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87584.1 - 3.7e-27 95.2 0.0 4.3e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII87584.1 - 0.0016 17.8 0.0 0.0056 16.0 0.0 1.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KII87584.1 - 0.0051 16.8 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII87584.1 - 0.02 14.2 0.0 0.048 13.0 0.0 1.5 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KII87584.1 - 0.025 14.2 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KII87584.1 - 0.085 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KII87584.1 - 0.2 10.6 0.1 0.2 10.6 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Transp_cyt_pur PF02133.15 KII87587.1 - 1.1e-142 475.9 43.0 1.4e-142 475.6 43.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 KII87587.1 - 0.2 11.6 3.2 0.42 10.6 0.4 3.1 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) 6PF2K PF01591.18 KII87588.1 - 7.6e-64 215.1 0.0 1.2e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KII87588.1 - 4.6e-24 85.2 0.0 7.1e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KII87588.1 - 6.1e-05 23.2 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KII87588.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Toprim_3 PF13362.6 KII87588.1 - 0.071 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Toprim domain IGR PF09597.10 KII87588.1 - 0.11 12.6 0.2 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 IGR protein motif tRNA_lig_kinase PF08303.11 KII87588.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 tRNA ligase kinase domain RRM_1 PF00076.22 KII87589.1 - 4.4e-15 55.2 0.4 7.6e-15 54.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KII87589.1 - 0.00064 20.2 0.1 0.0012 19.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF4316 PF14195.6 KII87589.1 - 0.63 9.8 2.1 2.6 7.9 2.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) MMR_HSR1 PF01926.23 KII87590.1 - 2.8e-11 43.5 0.0 7.9e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII87590.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KII87590.1 - 0.0079 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KII87590.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KII87590.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KII87590.1 - 0.028 13.5 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain IIGP PF05049.13 KII87590.1 - 0.029 13.4 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 KII87590.1 - 0.03 13.8 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 KII87590.1 - 0.068 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KII87590.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Dynamin family DUF5370 PF17340.2 KII87590.1 - 0.11 12.4 0.1 0.58 10.1 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5370) Herpes_UL47 PF03362.13 KII87590.1 - 0.27 10.0 0.2 0.38 9.5 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein MFS_1 PF07690.16 KII87593.1 - 1.1e-19 70.6 50.8 6e-15 55.0 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEN-2 PF10251.9 KII87593.1 - 2.4 8.6 6.2 0.71 10.3 0.4 2.8 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase RNA_pol_L_2 PF13656.6 KII87594.1 - 2.2e-25 88.2 0.0 3e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KII87594.1 - 2e-09 36.8 0.0 3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KII87594.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 2 0 0 2 2 2 0 Rio2, N-terminal Ribosomal_L27A PF00828.19 KII87595.1 - 1.2e-21 77.7 0.0 1.8e-21 77.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-C3HC4_3 PF13920.6 KII87596.1 - 2.2e-11 43.4 6.2 1.3e-09 37.7 1.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII87596.1 - 0.00059 19.7 2.7 0.0014 18.4 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII87596.1 - 0.002 18.4 6.2 0.0045 17.3 2.0 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KII87596.1 - 0.0021 17.9 5.2 0.0021 17.9 5.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KII87596.1 - 0.0049 16.8 3.0 0.036 14.0 0.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain PA PF02225.22 KII87596.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 PA domain zf-RING_UBOX PF13445.6 KII87596.1 - 1.3 9.1 6.5 15 5.7 0.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger HLH PF00010.26 KII87598.1 - 3.5e-09 36.5 0.0 1.5e-08 34.5 0.0 2.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PKcGMP_CC PF16808.5 KII87598.1 - 0.0079 16.0 0.7 0.016 15.1 0.7 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF922 PF06037.11 KII87598.1 - 0.18 11.6 0.2 0.35 10.7 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Pkinase PF00069.25 KII87599.1 - 1.2e-64 218.3 0.0 2.6e-64 217.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87599.1 - 2.1e-32 112.4 0.0 3.8e-32 111.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII87599.1 - 0.00012 22.1 0.0 0.00073 19.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KII87599.1 - 0.21 10.5 0.1 0.32 9.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPR PF01535.20 KII87600.1 - 4.7e-17 61.0 0.4 0.0015 18.7 0.0 5.7 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 KII87600.1 - 1.5e-12 46.9 0.0 0.021 14.5 0.0 3.7 3 0 0 3 3 3 3 PPR repeat PPR_2 PF13041.6 KII87600.1 - 6.5e-12 45.5 0.0 0.086 13.1 0.0 5.2 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KII87600.1 - 1e-09 38.3 0.0 0.0056 16.7 0.0 3.7 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KII87600.1 - 5.1e-05 22.7 0.0 0.1 11.9 0.0 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 KII87600.1 - 0.016 15.7 1.3 0.55 10.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SKG6 PF08693.10 KII87601.1 - 0.00044 19.6 2.7 0.00091 18.6 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KII87601.1 - 0.037 13.8 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KII87601.1 - 0.091 13.6 0.0 0.26 12.2 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TraT PF05818.12 KII87601.1 - 0.46 10.1 2.3 0.93 9.1 2.3 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein p450 PF00067.22 KII87602.1 - 5.5e-69 233.1 0.0 6.9e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWIRM PF04433.17 KII87603.1 - 3.4e-32 110.6 0.0 1.4e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KII87603.1 - 4.4e-22 77.8 7.7 8.4e-22 76.9 7.7 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KII87603.1 - 9.8e-11 41.7 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII87603.1 - 6.7e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KII87603.1 - 1.8e-08 34.1 3.5 2.9e-08 33.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Flot PF15975.5 KII87603.1 - 0.026 14.7 3.9 0.088 13.0 3.9 1.9 1 0 0 1 1 1 0 Flotillin ADH_N PF08240.12 KII87606.1 - 4.2e-29 100.6 1.6 7.1e-29 99.9 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII87606.1 - 2.6e-26 92.1 0.6 5.2e-26 91.1 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII87606.1 - 0.00022 22.3 0.2 0.00042 21.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KII87606.1 - 0.04 13.4 0.6 0.28 10.6 0.1 2.5 3 0 0 3 3 3 0 short chain dehydrogenase TOBE_2 PF08402.10 KII87606.1 - 0.087 13.0 0.1 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 TOBE domain CHAP PF05257.16 KII87606.1 - 0.13 12.8 1.2 0.83 10.3 0.1 2.5 3 0 0 3 3 3 0 CHAP domain FMO-like PF00743.19 KII87607.1 - 1.9e-24 86.0 0.0 1.9e-13 49.7 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII87607.1 - 3.9e-13 49.3 0.0 6.4e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII87607.1 - 3.4e-06 26.5 0.0 0.00016 21.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII87607.1 - 9.8e-05 21.6 0.0 0.00077 18.7 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KII87607.1 - 0.011 15.7 0.7 15 5.5 0.0 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.26 KII87609.1 - 2.8e-28 98.5 0.2 5.2e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII87609.1 - 8.7e-28 96.4 1.9 1.4e-27 95.7 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII87609.1 - 9.3e-06 26.7 0.2 1.7e-05 25.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FYVE PF01363.21 KII87610.1 - 1.1e-08 35.1 6.1 1.6e-08 34.6 6.1 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KII87610.1 - 0.0037 17.5 12.2 0.014 15.6 12.2 1.8 1 1 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 KII87610.1 - 0.021 14.7 7.9 0.036 14.0 3.4 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 KII87610.1 - 0.2 11.7 6.1 0.087 12.9 1.8 2.2 2 1 0 2 2 2 0 RING-type zinc-finger HypA PF01155.19 KII87610.1 - 1.4 8.9 8.6 3.1 7.9 8.6 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 KII87610.1 - 2 8.7 16.4 5.6 7.2 12.3 2.9 2 1 1 3 3 3 0 AN1-like Zinc finger IBR PF01485.21 KII87610.1 - 2.4 8.5 15.3 2.5 8.4 5.6 2.7 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 KII87611.1 - 8.1e-14 51.2 8.1 1.3e-13 50.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII87611.1 - 8.1e-09 35.2 7.5 1.3e-08 34.6 7.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KII87611.1 - 2.3e-07 31.0 7.4 3.6e-07 30.4 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII87611.1 - 2.9e-05 23.8 9.3 4.7e-05 23.2 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KII87611.1 - 0.0014 18.2 3.3 0.0024 17.5 3.3 1.3 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4_2 PF13923.6 KII87611.1 - 0.0024 17.7 9.0 0.0037 17.1 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII87611.1 - 0.023 14.7 6.4 0.044 13.7 6.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.6 KII87611.1 - 0.081 13.1 3.4 0.31 11.2 2.3 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KII87611.1 - 0.2 11.5 5.1 0.38 10.6 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec23_trunk PF04811.15 KII87612.1 - 7.8e-70 235.2 0.0 1.5e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KII87612.1 - 1.3e-21 76.3 0.1 3.3e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KII87612.1 - 1.1e-17 64.5 0.1 2.9e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KII87612.1 - 4.1e-16 58.7 6.6 7.8e-16 57.9 6.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KII87612.1 - 1.4e-08 34.6 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 KII87612.1 - 5.2e-06 26.4 2.8 5.2e-06 26.4 2.8 2.2 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 KII87612.1 - 0.00074 18.9 0.5 0.0015 17.9 0.5 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain RSN1_7TM PF02714.15 KII87613.1 - 1.5e-79 267.2 20.7 2.3e-79 266.6 20.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KII87613.1 - 6.8e-38 129.9 4.5 6.8e-38 129.9 4.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KII87613.1 - 5.2e-30 105.0 0.0 1.4e-21 77.5 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KII87613.1 - 5.1e-13 49.0 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter ATP-synt_10 PF05176.14 KII87614.1 - 7.8e-59 199.0 0.0 1e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF155 PF02582.14 KII87615.1 - 9e-45 152.9 0.0 1.6e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PRiA4_ORF3 PF07929.11 KII87616.1 - 3.8e-07 30.0 0.0 1e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein TPT PF03151.16 KII87617.1 - 1.1e-22 80.7 19.4 1.4e-22 80.4 19.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family LSM PF01423.22 KII87618.1 - 2.6e-16 59.1 0.2 3e-16 58.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF563 PF04577.14 KII87619.1 - 8.6e-07 29.3 0.0 1.4e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pkinase PF00069.25 KII87620.1 - 5.3e-64 216.1 0.0 6.3e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87620.1 - 1.7e-27 96.3 0.0 2.6e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII87620.1 - 3.9e-06 26.4 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII87620.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII87620.1 - 0.00094 18.8 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KII87620.1 - 0.0023 17.9 0.1 1.3 8.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII87620.1 - 0.008 15.2 0.4 0.016 14.2 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Phage_sheath_1C PF17482.2 KII87620.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain NTF2 PF02136.20 KII87621.1 - 2e-27 96.1 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KII87621.1 - 5.1e-06 26.2 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.11 KII87622.1 - 1.9e-219 729.9 0.0 2.4e-219 729.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C MIT PF04212.18 KII87624.1 - 0.0041 17.2 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain DEAD PF00270.29 KII87625.1 - 4.5e-39 134.0 0.0 2.8e-37 128.2 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII87625.1 - 7.1e-27 93.9 0.0 7.1e-26 90.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII87625.1 - 1.8e-05 24.8 0.0 4.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EXS PF03124.14 KII87627.1 - 3.4e-81 273.1 19.6 4.3e-81 272.8 19.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KII87627.1 - 8.7e-53 180.6 0.4 1.9e-52 179.5 0.1 1.7 2 1 0 2 2 2 1 SPX domain Big_9 PF17963.1 KII87629.1 - 0.073 13.8 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig domain RmlD_sub_bind PF04321.17 KII87630.1 - 6.7e-49 166.5 0.0 7.9e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KII87630.1 - 1.8e-21 76.7 0.0 2.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KII87630.1 - 1.3e-06 27.8 0.0 0.00022 20.5 0.0 2.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KII87630.1 - 7.9e-06 25.5 0.0 1.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII87630.1 - 0.00022 20.5 0.0 0.26 10.4 0.0 3.0 1 1 1 2 2 2 2 Male sterility protein Vps16_C PF04840.12 KII87631.1 - 2e-86 289.9 0.1 2.7e-86 289.5 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KII87631.1 - 2.1e-79 267.2 0.0 3e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region RIB43A PF05914.12 KII87631.1 - 0.015 14.1 1.7 0.023 13.4 1.7 1.2 1 0 0 1 1 1 0 RIB43A F-box-like PF12937.7 KII87632.1 - 4.6e-05 23.2 0.2 0.00012 21.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII87632.1 - 0.0069 16.2 0.0 0.041 13.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain Tim44 PF04280.15 KII87633.1 - 0.00064 19.8 0.3 0.0015 18.6 0.3 1.7 1 1 0 1 1 1 1 Tim44-like domain MRP-S32 PF10210.9 KII87633.1 - 0.015 15.9 0.5 0.052 14.1 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 CHCH PF06747.13 KII87634.1 - 0.002 18.2 3.3 0.0081 16.3 3.4 1.8 1 1 1 2 2 2 2 CHCH domain DUF2076 PF09849.9 KII87634.1 - 0.093 12.8 3.5 0.1 12.6 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sec62 PF03839.16 KII87635.1 - 7.3e-53 179.3 4.6 1.9e-52 177.9 4.6 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 TPR_12 PF13424.6 KII87636.1 - 1.8e-06 28.1 5.0 0.004 17.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII87636.1 - 0.022 14.9 1.4 52 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII87636.1 - 0.022 15.6 2.5 2.4 9.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KII87636.1 - 0.027 15.0 2.2 0.23 12.0 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KII87636.1 - 0.17 12.1 0.2 55 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KII87636.1 - 2.7 8.9 0.0 2.7 8.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Terpene_synth_C PF03936.16 KII87637.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KII87637.1 - 0.0005 20.1 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 Sporulation initiation phospho-transferase B, C-terminal UPF0113 PF03657.13 KII87637.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain MFS_1 PF07690.16 KII87638.1 - 6.7e-24 84.5 29.3 1.9e-19 69.8 7.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII87638.1 - 0.00033 19.7 9.5 0.00057 18.9 9.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KII87638.1 - 0.086 11.7 16.3 1.5 7.6 0.3 3.0 2 1 0 2 2 2 0 MFS_1 like family SR-25 PF10500.9 KII87639.1 - 0.48 10.0 8.6 0.11 12.1 5.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tox-HNH-HHH PF15637.6 KII87640.1 - 0.029 14.5 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif GGACT PF06094.12 KII87642.1 - 1.6e-15 57.8 0.0 2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like WD40 PF00400.32 KII87643.1 - 3.7e-46 154.1 23.3 4.8e-09 36.7 0.1 12.3 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87643.1 - 6.1e-28 97.0 0.0 0.0041 17.4 0.0 9.6 2 2 6 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KII87643.1 - 2.8e-26 91.9 0.1 4.4e-26 91.3 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KII87643.1 - 6.7e-11 41.7 2.8 0.11 11.5 0.0 6.9 3 2 4 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 KII87643.1 - 5.7e-06 26.3 0.1 0.015 15.1 0.0 4.5 3 3 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 KII87643.1 - 3e-05 23.5 0.0 0.34 10.2 0.0 4.0 3 2 1 4 4 4 2 WD40-like domain PD40 PF07676.12 KII87643.1 - 0.00018 21.3 3.1 3.4 7.7 0.0 7.0 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KII87643.1 - 0.0011 17.5 0.5 6.7 5.1 0.0 3.7 4 0 0 4 4 4 2 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 KII87643.1 - 0.0025 17.2 0.0 0.23 10.7 0.0 3.7 5 1 1 6 6 6 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KII87643.1 - 0.016 13.8 0.0 0.039 12.6 0.0 1.6 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin DUF1513 PF07433.11 KII87643.1 - 0.077 12.1 0.4 3.1 6.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) Utp8 PF10395.9 KII87643.1 - 0.15 10.5 0.0 9 4.7 0.0 2.8 2 1 0 3 3 3 0 Utp8 family Cnd1 PF12717.7 KII87644.1 - 4.6e-56 189.3 0.7 3.6e-51 173.4 0.2 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 KII87644.1 - 4e-54 182.9 0.0 4e-54 182.9 0.0 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 KII87644.1 - 1e-07 32.2 1.1 0.064 13.7 0.0 5.4 6 0 0 6 6 6 2 HEAT repeats Adaptin_N PF01602.20 KII87644.1 - 3.8e-06 25.8 2.9 0.0046 15.6 0.6 3.7 3 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 KII87644.1 - 0.0004 20.4 2.9 85 3.8 0.0 6.5 6 0 0 6 6 6 0 HEAT repeat RTP1_C1 PF10363.9 KII87644.1 - 0.0045 17.2 0.8 5.2 7.3 0.1 3.7 2 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 YtzH PF14165.6 KII87644.1 - 0.0081 16.5 1.0 0.062 13.7 0.1 3.1 3 1 1 4 4 4 1 YtzH-like protein Cnd3 PF12719.7 KII87644.1 - 0.015 14.5 0.8 0.31 10.2 0.4 2.7 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain PIP5K PF01504.18 KII87645.1 - 5.6e-102 340.6 0.0 9.6e-102 339.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SSP160 PF06933.11 KII87646.1 - 0.61 8.2 9.9 0.62 8.2 9.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_C50 PF03568.17 KII87647.1 - 2.1e-141 471.6 0.0 3.2e-141 471.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 KII87647.1 - 9.2e-07 29.1 16.0 0.022 15.1 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KII87647.1 - 0.00046 19.7 0.2 0.002 17.6 0.2 2.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 KII87647.1 - 0.00089 19.2 6.6 4.5 7.6 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII87647.1 - 0.0056 16.5 0.4 7.8 6.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII87647.1 - 0.14 12.4 0.0 47 4.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII87647.1 - 0.22 11.6 1.6 15 5.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1771 PF08590.10 KII87647.1 - 0.27 11.6 2.0 33 4.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) ANAPC3 PF12895.7 KII87647.1 - 1.3 9.4 3.2 1.6e+02 2.6 0.1 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KII87647.1 - 2.3 8.2 11.8 0.71 9.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KII87648.1 - 2.9e-41 141.6 0.0 1.4e-35 122.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IreB PF06135.12 KII87648.1 - 0.012 15.8 0.1 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 IreB regulatory phosphoprotein CNH PF00780.22 KII87649.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 CNH domain CBS PF00571.28 KII87650.1 - 2.3e-18 66.4 0.2 0.00014 22.2 0.1 4.5 4 0 0 4 4 4 4 CBS domain CIF PF16374.5 KII87650.1 - 0.0082 16.2 0.0 0.026 14.6 0.0 1.8 1 1 0 1 1 1 1 Cycle inhibiting factor (CIF) F-box PF00646.33 KII87651.1 - 0.00046 20.0 1.6 0.001 18.9 1.6 1.6 1 0 0 1 1 1 1 F-box domain Ion_trans_2 PF07885.16 KII87652.1 - 9.3e-21 73.6 32.6 2.6e-12 46.5 9.9 3.4 3 0 0 3 3 3 2 Ion channel Tetraspanin PF00335.20 KII87652.1 - 0.016 14.9 0.4 0.016 14.9 0.4 2.9 2 2 0 3 3 3 0 Tetraspanin family Lig_chan PF00060.26 KII87652.1 - 0.093 12.6 5.9 2.6 7.9 0.2 2.8 1 1 0 2 2 2 0 Ligand-gated ion channel DUF3267 PF11667.8 KII87652.1 - 0.16 12.2 10.1 4.5 7.6 1.2 3.6 3 1 0 3 3 3 0 Putative zincin peptidase Ion_trans PF00520.31 KII87652.1 - 1.2 8.3 12.1 1.1 8.4 0.8 2.7 2 1 0 2 2 2 0 Ion transport protein DUF4231 PF14015.6 KII87652.1 - 2 8.9 9.1 7.2 7.1 1.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Glyco_transf_24 PF18404.1 KII87653.1 - 1.8e-144 480.1 1.5 3e-144 479.3 1.5 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KII87653.1 - 4.2e-62 210.4 0.0 4.2e-61 207.1 0.1 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KII87653.1 - 1e-48 165.8 0.0 2.5e-48 164.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KII87653.1 - 5.5e-42 142.9 0.0 1.7e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KII87653.1 - 6.9e-40 135.6 0.0 1.7e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 KII87653.1 - 3.6e-39 134.9 0.0 3e-37 128.6 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KII87653.1 - 4.2e-05 23.2 0.0 7.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ldl_recept_a PF00057.18 KII87655.1 - 0.051 13.8 5.6 0.051 13.8 5.6 1.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Mu-conotoxin PF05374.12 KII87655.1 - 0.53 10.3 10.2 2.1 8.4 3.1 3.3 3 0 0 3 3 3 0 Mu-Conotoxin E1-E2_ATPase PF00122.20 KII87656.1 - 4.1e-48 163.3 0.0 4.1e-48 163.3 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KII87656.1 - 1.8e-18 67.6 2.6 6.3e-18 65.8 2.6 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KII87656.1 - 1.8e-11 43.5 0.0 4.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII87656.1 - 0.0002 21.2 0.3 0.0011 18.8 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KII87656.1 - 0.0047 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) adh_short PF00106.25 KII87657.1 - 8.3e-27 93.9 0.0 1e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87657.1 - 1.2e-21 77.3 0.0 1.5e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KII87657.1 - 0.0089 15.9 0.1 0.012 15.5 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KII87657.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC2_membrane PF01061.24 KII87658.1 - 4.7e-74 248.3 55.9 7.7e-40 136.6 18.8 4.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KII87658.1 - 1.2e-37 129.4 0.0 2.9e-17 63.5 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KII87658.1 - 1.6e-31 108.0 17.0 7.4e-29 99.5 0.8 3.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KII87658.1 - 7.2e-18 65.0 0.1 1.8e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KII87658.1 - 8e-09 36.1 0.1 0.00028 21.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KII87658.1 - 2e-06 28.1 0.3 0.085 13.1 0.2 3.5 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KII87658.1 - 2.6e-06 27.4 0.1 0.00015 21.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KII87658.1 - 5.4e-06 26.1 0.0 0.00085 18.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII87658.1 - 0.00015 21.9 0.1 0.41 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII87658.1 - 0.00026 20.7 0.2 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII87658.1 - 0.00054 20.0 0.1 0.7 10.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KII87658.1 - 0.00066 19.6 0.4 0.17 11.8 0.2 2.9 3 0 0 3 3 2 1 NACHT domain ABC2_membrane_3 PF12698.7 KII87658.1 - 0.00078 18.6 21.2 0.00078 18.6 21.2 3.6 2 1 0 3 3 3 1 ABC-2 family transporter protein dNK PF01712.19 KII87658.1 - 0.00098 19.0 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_18 PF13238.6 KII87658.1 - 0.0013 19.3 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KII87658.1 - 0.0016 18.3 0.2 0.85 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KII87658.1 - 0.0024 18.1 0.5 1.4 9.1 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KII87658.1 - 0.019 15.4 0.1 8.8 6.8 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KII87658.1 - 0.024 15.0 0.1 4.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KII87658.1 - 0.032 13.9 0.5 1.5 8.5 0.6 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KII87658.1 - 0.044 13.4 2.1 0.98 9.0 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KII87658.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KII87658.1 - 0.086 12.6 0.6 4.5 7.0 0.3 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KII87658.1 - 0.16 11.2 0.1 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KII87658.1 - 0.17 12.1 0.1 3.3 7.9 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KII87658.1 - 0.18 11.0 0.1 6.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 KII87658.1 - 0.18 12.2 0.0 7.3 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KII87658.1 - 0.2 11.6 0.0 29 4.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 KII87658.1 - 0.2 11.7 0.4 0.6 10.1 0.1 2.0 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KII87658.1 - 0.21 11.5 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2721 PF11026.8 KII87658.1 - 5.7 6.8 16.6 2.1 8.2 0.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RabGAP-TBC PF00566.18 KII87659.1 - 2.2e-17 63.4 0.0 3.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3040 PF11239.8 KII87659.1 - 0.17 12.2 1.5 0.36 11.1 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RNA_pol_N PF01194.17 KII87660.1 - 4e-32 110.3 0.4 4.8e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.9 KII87660.1 - 0.029 13.8 0.2 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com Amidase PF01425.21 KII87664.1 - 4.4e-109 365.4 0.0 5.1e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Amidase F-box-like PF12937.7 KII87665.1 - 1.2e-10 41.1 1.0 2.5e-10 40.1 1.0 1.5 1 1 0 1 1 1 1 F-box-like DUF5535 PF17687.1 KII87665.1 - 0.048 13.8 0.0 0.09 12.9 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5535) F-box PF00646.33 KII87665.1 - 0.44 10.5 5.2 4.2 7.4 1.2 2.6 2 1 0 2 2 2 0 F-box domain Pkinase PF00069.25 KII87666.1 - 2.2e-72 243.6 0.0 4.4e-72 242.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87666.1 - 1.5e-41 142.4 0.0 2.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KII87666.1 - 1.1e-36 124.9 1.6 1.2e-18 67.1 0.2 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KII87666.1 - 6.7e-08 32.2 0.0 5.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.6 KII87666.1 - 0.061 13.4 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Haspin_kinase PF12330.8 KII87666.1 - 0.066 12.1 0.7 0.1 11.5 0.0 1.7 2 1 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KII87666.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII87666.1 - 0.65 9.9 2.8 0.62 9.9 0.3 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cys_Met_Meta_PP PF01053.20 KII87669.1 - 1.9e-23 82.7 0.0 3.2e-23 81.9 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KII87669.1 - 0.00071 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II F-box PF00646.33 KII87670.1 - 0.0005 19.9 0.3 0.0013 18.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain DUF1451 PF07295.11 KII87671.1 - 0.008 16.2 0.3 0.027 14.5 0.2 1.9 2 0 0 2 2 2 1 Zinc-ribbon containing domain Apolipoprotein PF01442.18 KII87671.1 - 0.017 15.0 5.2 0.039 13.8 5.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 KII87671.1 - 0.037 14.1 3.8 0.95 9.5 1.4 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 KII87671.1 - 0.043 13.9 3.9 0.38 10.8 4.4 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 KII87671.1 - 0.15 10.0 0.7 0.2 9.6 0.7 1.1 1 0 0 1 1 1 0 Prominin F-box PF00646.33 KII87672.1 - 0.0022 17.8 0.1 0.0054 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain PPTA PF01239.22 KII87673.1 - 5.2e-39 130.9 14.8 9.7e-09 34.7 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RRM_1 PF00076.22 KII87674.1 - 3.8e-14 52.3 0.0 4.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII87674.1 - 0.0031 17.3 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RNA_pol_3_Rpc31 PF11705.8 KII87675.1 - 1.3e-26 94.3 4.2 2.2e-26 93.5 4.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Vps39_2 PF10367.9 KII87677.1 - 3.3e-10 40.4 0.1 1.3e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KII87677.1 - 4.3e-08 33.4 0.4 1.8e-06 28.2 0.1 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KII87677.1 - 3.1e-05 23.9 0.8 0.016 15.1 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS PreAtp-grasp PF18604.1 KII87677.1 - 0.083 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Pre ATP-grasp domain Glyco_transf_20 PF00982.21 KII87678.1 - 3.2e-152 507.5 0.0 4.9e-152 506.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KII87678.1 - 3.9e-71 238.9 0.0 7.7e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase RRM_1 PF00076.22 KII87679.1 - 2.5e-50 168.2 0.0 1.6e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KII87679.1 - 0.0027 17.7 0.0 0.52 10.4 0.0 3.4 3 2 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 KII87679.1 - 0.0033 17.0 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 KII87679.1 - 0.0063 15.9 0.0 0.054 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) gpW PF02831.15 KII87679.1 - 0.036 14.0 0.2 0.43 10.5 0.0 2.5 3 0 0 3 3 3 0 gpW MFS_5 PF05631.14 KII87680.1 - 1.3e-71 241.4 5.0 1.9e-71 240.9 5.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KII87680.1 - 3.7e-17 62.3 31.5 3.7e-17 62.3 31.5 2.1 1 1 2 3 3 3 2 Major Facilitator Superfamily FrhB_FdhB_N PF04422.13 KII87680.1 - 0.071 13.3 0.1 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PCMT PF01135.19 KII87681.1 - 2.6e-72 243.0 0.2 3e-72 242.8 0.2 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KII87681.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII87681.1 - 4.6e-08 33.7 0.0 1.7e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87681.1 - 1.1e-05 26.0 0.0 2.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII87681.1 - 3.8e-05 23.2 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KII87681.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KII87681.1 - 0.00019 21.0 0.0 0.00045 19.7 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KII87681.1 - 0.00043 20.2 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KII87681.1 - 0.0007 19.3 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 KII87681.1 - 0.0013 18.3 0.1 0.0035 16.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KII87681.1 - 0.0074 16.4 0.1 0.021 15.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 KII87681.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 KII87681.1 - 0.022 13.9 0.2 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 Fibrillarin Methyltransf_18 PF12847.7 KII87681.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mem_trans PF03547.18 KII87682.1 - 1.8e-33 115.5 11.4 6.7e-30 103.7 0.9 2.9 2 1 0 2 2 2 2 Membrane transport protein DUF3084 PF11283.8 KII87682.1 - 0.028 14.4 1.0 7.9 6.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) GAS2 PF02187.17 KII87682.1 - 0.2 11.8 0.1 0.4 10.8 0.1 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Ferritin_2 PF13668.6 KII87683.1 - 1.2e-40 138.9 0.3 1.7e-40 138.4 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain Aldedh PF00171.22 KII87684.1 - 1.3e-82 277.7 0.0 1.6e-82 277.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5560 PF17715.1 KII87684.1 - 0.019 14.4 0.3 0.041 13.3 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5560) FA_desaturase PF00487.24 KII87686.1 - 1.2e-27 97.4 24.7 2e-27 96.6 24.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KII87686.1 - 2.9e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF802 PF05650.11 KII87690.1 - 0.05 14.1 1.7 0.05 14.1 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) MAM33 PF02330.16 KII87691.1 - 4.1e-71 239.3 0.6 4.7e-71 239.1 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2011 PF09428.10 KII87692.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DBD_HTH PF18430.1 KII87692.1 - 0.2 11.4 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Putative DNA-binding domain APH PF01636.23 KII87695.1 - 5.2e-16 59.3 0.2 8e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII87695.1 - 0.00068 19.3 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KII87697.1 - 3.7e-17 63.1 0.1 5.8e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII87697.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KII87697.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII87697.1 - 0.18 11.4 0.0 0.62 9.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family zf-MYND PF01753.18 KII87698.1 - 2.3e-11 43.6 13.0 4.3e-11 42.7 13.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII87698.1 - 2.1 8.7 11.6 6 7.3 11.6 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-RING_2 PF13639.6 KII87699.1 - 1.3e-13 51.0 4.9 1.7e-13 50.7 4.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KII87699.1 - 3.4e-11 43.2 10.3 1.8e-09 37.8 10.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KII87699.1 - 8.6e-10 38.3 4.2 1.3e-09 37.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII87699.1 - 1.5e-08 34.4 2.7 2e-08 33.9 2.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII87699.1 - 3.5e-08 33.3 3.9 4.5e-08 32.9 3.9 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KII87699.1 - 6.7e-08 32.1 2.3 1.2e-07 31.4 2.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KII87699.1 - 2.2e-07 30.8 6.2 3.4e-06 27.0 6.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KII87699.1 - 4.9e-07 29.5 1.9 7.5e-07 28.9 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII87699.1 - 1.1e-06 28.6 1.4 1.7e-06 27.9 1.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KII87699.1 - 4.2e-05 23.6 7.5 0.00091 19.4 7.5 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-P11 PF03854.14 KII87699.1 - 8.9e-05 22.1 1.5 0.00039 20.0 0.3 2.0 2 0 0 2 2 2 1 P-11 zinc finger Prok-RING_4 PF14447.6 KII87699.1 - 0.00092 19.0 5.3 0.0026 17.6 5.4 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KII87699.1 - 0.0027 17.3 6.6 0.0051 16.4 6.6 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KII87699.1 - 0.01 16.1 3.4 0.01 16.1 3.4 1.5 2 0 0 2 2 1 0 RING-like domain Prok-RING_1 PF14446.6 KII87699.1 - 0.015 15.2 3.1 0.28 11.1 0.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.7 KII87699.1 - 0.02 15.0 5.2 0.045 13.9 5.2 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KII87699.1 - 0.025 14.4 1.6 0.039 13.7 1.6 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_16 PF17034.5 KII87699.1 - 0.026 14.7 3.4 0.042 14.1 3.3 1.3 1 1 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 KII87699.1 - 0.027 14.3 1.1 0.051 13.4 1.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tmpp129 PF10272.9 KII87699.1 - 0.11 11.8 1.4 0.15 11.3 1.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor PHD PF00628.29 KII87699.1 - 0.14 12.1 5.0 0.28 11.1 5.0 1.6 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 KII87699.1 - 0.17 12.0 3.6 0.18 11.8 1.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon Cnd3 PF12719.7 KII87700.1 - 1.4e-75 254.3 0.2 2.6e-74 250.1 0.0 2.9 2 2 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KII87700.1 - 3.6e-06 27.3 5.0 2.8e-05 24.4 0.3 3.8 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 KII87700.1 - 6.1e-06 26.0 2.9 1.1 9.7 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KII87700.1 - 0.034 14.7 3.0 11 6.7 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat RTP1_C1 PF10363.9 KII87700.1 - 0.035 14.3 0.5 0.41 10.8 0.0 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KII87700.1 - 0.037 14.1 2.1 2.2 8.3 0.0 4.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF4521 PF15021.6 KII87700.1 - 0.051 13.5 1.7 0.068 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) Homoserine_dh PF00742.19 KII87701.1 - 1.1e-45 155.6 0.0 1.5e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KII87701.1 - 7e-20 71.8 0.0 1.1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KII87701.1 - 0.004 17.6 0.0 0.015 15.8 0.0 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Aldedh PF00171.22 KII87702.1 - 1.1e-86 291.2 0.0 1.3e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PNRC PF15365.6 KII87705.1 - 0.032 14.1 2.0 0.032 14.1 2.0 3.8 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif COX8 PF02285.15 KII87706.1 - 2.3 8.1 6.1 0.17 11.8 0.9 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII HECT_2 PF09814.9 KII87707.1 - 2.9e-50 171.2 0.0 4e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF676 PF05057.14 KII87708.1 - 5.2e-39 134.0 0.0 7.9e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KII87708.1 - 3.2e-05 23.8 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 KII87708.1 - 0.0078 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KII87708.1 - 0.018 15.6 0.1 0.073 13.7 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KII87708.1 - 0.068 12.9 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein SPC25 PF06703.11 KII87709.1 - 1.4e-51 174.5 0.0 1.6e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) 4HBT PF03061.22 KII87709.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily MRP-S27 PF10037.9 KII87711.1 - 0.14 11.0 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 2-oxoacid_dh PF00198.23 KII87712.1 - 4.1e-81 271.8 0.1 5.6e-81 271.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KII87712.1 - 1.5e-18 66.4 0.4 2.9e-18 65.5 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KII87712.1 - 0.00014 21.6 0.0 0.031 14.1 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 KII87712.1 - 0.00042 21.0 0.1 0.55 11.0 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KII87712.1 - 0.0082 16.0 0.5 0.018 15.0 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF3614 PF12267.8 KII87712.1 - 0.53 10.8 6.7 4.2 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) F-box-like PF12937.7 KII87713.1 - 0.00028 20.7 0.5 0.00091 19.1 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII87713.1 - 0.064 13.2 0.2 0.2 11.5 0.2 1.8 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 KII87714.1 - 6.3e-13 49.0 6.8 0.00066 20.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87714.1 - 1.4e-07 31.7 0.0 0.18 12.1 0.0 4.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 KII87715.1 - 1.4e-12 48.6 0.2 2.4e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 KII87716.1 - 2.5e-13 51.0 0.1 3.5e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Gp5_C PF06715.12 KII87717.1 - 0.48 10.7 3.5 1.2 9.4 3.2 1.8 1 1 1 2 2 2 0 Gp5 C-terminal repeat (3 copies) Histone PF00125.24 KII87718.1 - 2.3e-17 63.6 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KII87718.1 - 2.6e-17 62.3 1.0 6.2e-17 61.0 1.0 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KII87718.1 - 2.2e-06 27.9 0.0 2.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII87719.1 - 1e-21 77.7 1.1 1.4e-21 77.2 1.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KII87719.1 - 0.00015 21.9 1.3 0.00019 21.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KII87719.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Phage_HK97_TLTM PF06120.11 KII87720.1 - 0.011 15.0 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein ERG2_Sigma1R PF04622.12 KII87721.1 - 2.1e-93 311.5 0.0 2.4e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein GRAB PF10375.9 KII87722.1 - 3.3e-06 26.7 0.3 7.9e-06 25.6 0.3 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain RasGAP_C PF03836.15 KII87722.1 - 0.31 11.2 9.4 0.089 12.9 5.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF1664 PF07889.12 KII87722.1 - 0.99 9.5 7.4 11 6.1 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KII87722.1 - 1.4 8.9 12.3 4.8 7.2 4.4 2.5 2 0 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 KII87722.1 - 3.2 8.2 35.4 0.3 11.5 16.7 3.1 1 1 2 3 3 3 0 Fez1 KLRAQ PF10205.9 KII87722.1 - 4.9 7.5 15.2 0.097 12.9 4.6 3.1 2 1 2 4 4 4 0 Predicted coiled-coil domain-containing protein RRM_1 PF00076.22 KII87723.1 - 1.6e-31 107.9 0.0 2.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3500 PF12006.8 KII87723.1 - 0.18 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Pkinase_fungal PF17667.1 KII87725.1 - 0.004 16.0 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cu-oxidase PF00394.22 KII87726.1 - 4.1e-45 153.7 0.2 3.6e-41 140.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII87726.1 - 4.8e-41 139.7 6.1 3.7e-39 133.6 0.2 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII87726.1 - 9.1e-37 125.7 0.4 1.3e-34 118.8 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase ADH_zinc_N_2 PF13602.6 KII87727.1 - 1.2e-21 78.2 0.0 2e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII87727.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KII87727.1 - 0.16 11.6 0.5 0.25 11.0 0.5 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Astacin PF01400.24 KII87730.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DmsC PF04976.12 KII87731.1 - 0.082 12.4 0.5 0.09 12.3 0.5 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) RelE PF06296.12 KII87738.1 - 1.5 9.0 5.3 0.39 10.8 0.2 2.5 3 0 0 3 3 3 0 RelE toxin of RelE / RelB toxin-antitoxin system Pkinase_fungal PF17667.1 KII87745.1 - 2e-20 73.0 0.0 2.2e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII87745.1 - 5.9e-05 22.6 0.0 6.4e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII87745.1 - 0.00035 20.6 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII87745.1 - 0.017 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KII87745.1 - 0.025 13.8 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Phage_integrase PF00589.22 KII87746.1 - 0.0088 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Phage integrase family RVT_thumb PF06817.14 KII87748.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase thumb domain Ish1 PF10281.9 KII87751.1 - 0.00039 20.7 1.4 0.06 13.7 0.0 2.5 2 0 0 2 2 2 2 Putative stress-responsive nuclear envelope protein Pkinase_fungal PF17667.1 KII87753.1 - 3.2e-20 72.3 0.0 4e-19 68.7 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase Gag_p19 PF02228.16 KII87755.1 - 1.1 9.8 4.9 21 5.6 0.3 2.9 2 1 1 3 3 3 0 Major core protein p19 LEA_6 PF10714.9 KII87758.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 zf-CCHC PF00098.23 KII87759.1 - 0.0044 17.0 3.6 0.0081 16.2 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Phostensin_N PF13916.6 KII87759.1 - 0.21 12.0 1.8 0.36 11.2 1.1 1.7 1 1 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal OPT PF03169.15 KII87761.1 - 1.5e-92 311.2 39.4 1.8e-92 311.0 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KII87761.1 - 4.5 7.5 6.4 0.59 10.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Amino_oxidase PF01593.24 KII87764.1 - 8e-35 121.0 0.0 1.1e-34 120.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII87764.1 - 2.6e-10 40.4 3.2 3.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII87764.1 - 5.7e-07 29.4 0.0 5.7e-07 29.4 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII87764.1 - 0.0016 17.7 1.1 0.05 12.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KII87764.1 - 0.0017 17.2 0.0 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 MCRA family Pyr_redox PF00070.27 KII87764.1 - 0.0041 17.7 4.3 0.98 10.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII87764.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KII87764.1 - 0.033 12.9 0.1 6.5 5.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 KII87764.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Glyco_hydro_61 PF03443.14 KII87765.1 - 1.3e-47 162.5 0.0 1.7e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PWI PF01480.17 KII87767.1 - 4.8e-29 100.5 0.1 7.6e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 PWI domain GRP PF07172.11 KII87767.1 - 0.1 13.3 8.0 0.16 12.7 8.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_S41 PF03572.18 KII87768.1 - 1.7e-06 27.7 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 p450 PF00067.22 KII87769.1 - 6.5e-74 249.3 0.0 1.3e-73 248.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF3149 PF11346.8 KII87769.1 - 0.24 11.1 1.2 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TMEM154 PF15102.6 KII87770.1 - 0.00085 19.2 1.6 0.0013 18.6 0.0 2.2 2 1 1 3 3 3 1 TMEM154 protein family TMEM119 PF15724.5 KII87770.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 1 1 TMEM119 family Herpes_gE PF02480.16 KII87770.1 - 0.0045 15.8 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E PRIMA1 PF16101.5 KII87770.1 - 0.0052 16.8 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 KII87770.1 - 0.0073 17.2 0.1 0.019 15.9 0.1 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 KII87770.1 - 0.008 16.1 0.1 0.008 16.1 0.1 1.8 2 0 0 2 2 2 1 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 KII87770.1 - 0.017 14.9 1.6 0.035 13.9 1.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 KII87770.1 - 0.02 15.2 0.1 0.02 15.2 0.1 2.0 3 0 0 3 3 2 0 Wnt and FGF inhibitory regulator CD34_antigen PF06365.12 KII87770.1 - 0.023 14.3 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 0 CD34/Podocalyxin family Plasmodium_Vir PF05795.11 KII87770.1 - 0.028 13.8 0.0 0.071 12.5 0.0 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Protocadherin PF08374.11 KII87770.1 - 0.036 14.0 0.0 0.036 14.0 0.0 1.7 2 0 0 2 2 1 0 Protocadherin Ly49 PF08391.10 KII87770.1 - 0.054 13.9 0.0 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2207 PF09972.9 KII87770.1 - 0.065 12.0 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 KII87770.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Amnionless WBP-1 PF11669.8 KII87770.1 - 0.16 12.6 0.1 0.36 11.5 0.1 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 LapA_dom PF06305.11 KII87770.1 - 0.17 11.7 0.2 0.34 10.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mid2 PF04478.12 KII87770.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.8 2 0 0 2 2 1 0 Mid2 like cell wall stress sensor FeoB_associated PF12669.7 KII87770.1 - 0.3 11.5 1.9 1.5 9.2 1.9 2.1 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1180 PF06679.12 KII87770.1 - 6.2 7.2 13.7 0.06 13.8 1.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) ABC_tran PF00005.27 KII87771.1 - 3.1e-42 144.3 0.0 1.1e-22 81.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII87771.1 - 8.7e-31 107.6 31.1 5.3e-17 62.4 3.6 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region AAA_25 PF13481.6 KII87771.1 - 1.8e-05 24.4 0.0 0.025 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII87771.1 - 0.0011 18.7 1.0 0.68 9.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KII87771.1 - 0.0011 18.5 0.0 0.68 9.3 0.0 3.6 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KII87771.1 - 0.0032 17.7 0.0 5.1 7.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KII87771.1 - 0.0038 17.7 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KII87771.1 - 0.016 14.6 0.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF87 PF01935.17 KII87771.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 KII87771.1 - 0.064 12.3 0.1 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 KII87771.1 - 0.093 13.1 0.2 5.2 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.19 KII87771.1 - 1.7 8.2 3.5 1.6 8.3 0.6 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DNA_primase_S PF01896.19 KII87772.1 - 5.4e-53 179.7 0.0 7.1e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit GST_N_2 PF13409.6 KII87773.1 - 4.8e-19 68.4 0.0 1.2e-18 67.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII87773.1 - 2.2e-15 56.4 0.0 3.8e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII87773.1 - 1.2e-08 35.0 0.0 2.8e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII87773.1 - 4.6e-05 23.8 0.1 0.001 19.4 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KII87773.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 KII87773.1 - 0.11 13.2 0.1 8.6 7.0 0.0 2.4 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 ADH_N PF08240.12 KII87774.1 - 4.2e-29 100.6 0.5 8.3e-29 99.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII87774.1 - 6.9e-22 77.8 0.1 1.1e-21 77.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII87774.1 - 7.5e-11 41.9 0.3 8.1e-06 25.5 0.0 2.6 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII87774.1 - 1e-06 29.9 0.0 1.9e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KII87774.1 - 0.00059 19.2 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KII87774.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KII87774.1 - 0.039 14.7 0.1 0.11 13.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KII87774.1 - 0.048 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrmA PF06325.13 KII87774.1 - 0.051 13.0 0.1 0.084 12.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short_C2 PF13561.6 KII87775.1 - 7e-45 153.4 0.0 7.7e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII87775.1 - 7.4e-36 123.4 0.0 1.3e-35 122.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KII87775.1 - 0.0087 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.11 KII87775.1 - 0.069 12.8 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain Malic_M PF03949.15 KII87777.1 - 7e-88 294.2 0.0 9.1e-88 293.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KII87777.1 - 2.3e-63 213.3 0.0 3.9e-63 212.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF5415 PF17436.2 KII87777.1 - 0.062 13.4 0.2 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5415) DUF1845 PF08900.11 KII87779.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) LPG_synthase_TM PF03706.13 KII87781.1 - 0.011 15.3 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Trp_oprn_chp PF09534.10 KII87781.1 - 0.099 12.4 1.8 0.14 11.9 1.8 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CcmD PF04995.14 KII87781.1 - 0.75 9.9 3.6 1.6 8.9 3.6 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PGF-CTERM PF18204.1 KII87781.1 - 5.3 7.2 6.1 9.6 6.3 6.1 1.3 1 0 0 1 1 1 0 PGF-CTERM motif EMP24_GP25L PF01105.24 KII87782.1 - 1.3e-37 129.6 0.0 1.4e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KII87782.1 - 0.037 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Trimerisation motif Late_protein_L1 PF00500.18 KII87782.1 - 0.11 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 L1 (late) protein MR_MLE_C PF13378.6 KII87783.1 - 3.5e-57 193.5 0.3 4.5e-57 193.1 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KII87783.1 - 2.9e-24 85.5 0.0 6.3e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Pkinase_fungal PF17667.1 KII87784.1 - 1.5e-50 172.2 0.0 2.2e-30 105.8 0.4 2.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KII87784.1 - 0.00041 19.8 0.1 0.00071 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII87784.1 - 0.00042 20.3 0.4 0.0014 18.6 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII87784.1 - 0.084 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UQ_con PF00179.26 KII87785.1 - 3.9e-53 178.9 0.0 4.4e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII87785.1 - 0.0052 17.0 0.0 0.006 16.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KII87785.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KII87785.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Ndufs5 PF10200.9 KII87787.1 - 0.00051 20.2 0.2 0.00067 19.9 0.2 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 KII87787.1 - 0.011 15.7 1.0 0.017 15.1 1.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PADR1 PF08063.12 KII87787.1 - 0.015 15.1 1.5 1.5 8.6 0.8 2.7 3 0 0 3 3 3 0 PADR1 (NUC008) domain CHCH PF06747.13 KII87787.1 - 0.018 15.2 3.5 0.08 13.1 3.7 1.9 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 KII87787.1 - 0.69 10.3 5.5 4.6 7.7 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) ubiquitin PF00240.23 KII87788.1 - 3.6e-16 58.7 0.0 5.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KII87788.1 - 2.3e-07 30.5 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 KII87788.1 - 3.7e-06 27.3 2.8 7.2e-06 26.4 2.8 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain DUF2407 PF10302.9 KII87788.1 - 0.09 13.3 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain G-patch PF01585.23 KII87789.1 - 1.3e-05 25.0 0.1 1.9e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 G-patch domain Pkinase_fungal PF17667.1 KII87790.1 - 2e-48 165.2 0.0 8.7e-29 100.5 0.2 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KII87790.1 - 0.00045 20.2 0.4 0.0014 18.6 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 KII87790.1 - 0.0025 17.2 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII87790.1 - 0.028 13.7 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Nup96 PF12110.8 KII87791.1 - 1.3e-92 310.1 0.0 1.9e-92 309.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Pes-10 PF07149.11 KII87791.1 - 0.15 11.1 13.7 0.25 10.3 13.7 1.3 1 0 0 1 1 1 0 Pes-10 Rhabdo_ncap PF00945.18 KII87791.1 - 0.29 10.0 10.4 0.45 9.3 10.4 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop14 PF04147.12 KII87791.1 - 0.78 7.9 23.7 1.2 7.3 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 KII87791.1 - 1.7 6.9 7.5 2.3 6.4 7.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CCSAP PF15748.5 KII87791.1 - 2.4 8.3 10.9 3.9 7.6 10.9 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 KII87791.1 - 2.6 6.2 19.0 3.9 5.6 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KII87791.1 - 3.7 6.3 8.0 6 5.6 8.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain IFT57 PF10498.9 KII87791.1 - 8.5 5.2 8.6 13 4.6 8.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 adh_short PF00106.25 KII87792.1 - 2.2e-29 102.3 0.0 4.2e-29 101.4 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87792.1 - 7.6e-23 81.3 0.0 2.9e-22 79.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87792.1 - 0.00029 20.8 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII87792.1 - 0.0034 16.8 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KII87793.1 - 7.9e-29 100.5 0.0 1.4e-28 99.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87793.1 - 3.2e-22 79.2 0.0 1.1e-21 77.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87793.1 - 0.006 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KII87793.1 - 0.074 12.9 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 KII87793.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Oxidored_FMN PF00724.20 KII87794.1 - 1e-28 100.6 0.0 1.7e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TFIIE_alpha PF02002.17 KII87796.1 - 8.1e-21 73.9 0.2 1.6e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 KII87796.1 - 2.3e-06 27.8 0.4 2.3e-06 27.8 0.4 2.2 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Zn_Tnp_IS1595 PF12760.7 KII87796.1 - 0.044 13.8 0.9 0.087 12.8 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.6 KII87796.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger C1_4 PF07975.12 KII87796.1 - 0.061 13.6 1.8 1.1 9.5 0.1 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KII87796.1 - 0.13 12.2 2.4 0.48 10.4 2.4 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.6 KII87796.1 - 0.14 12.0 2.4 0.84 9.5 0.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Evr1_Alr PF04777.13 KII87796.1 - 0.16 12.5 1.5 0.68 10.4 1.6 1.9 1 1 1 2 2 2 0 Erv1 / Alr family Melibiase_2 PF16499.5 KII87797.1 - 2.1e-51 174.8 3.2 3.1e-51 174.2 3.2 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KII87797.1 - 2.1e-14 53.3 0.1 4.9e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KII87797.1 - 1.9e-05 23.8 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Melibiase WD40 PF00400.32 KII87798.1 - 4.7e-53 176.0 20.0 1.1e-07 32.4 1.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KII87798.1 - 4.6e-27 94.1 3.5 7.1e-27 93.5 3.5 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KII87798.1 - 1.3e-19 70.2 1.2 0.00024 21.3 0.0 6.6 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII87798.1 - 3.3e-11 43.1 0.1 0.01 15.2 0.0 4.8 5 1 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 KII87798.1 - 7.4e-08 31.7 1.2 1 8.2 0.0 5.5 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KII87798.1 - 0.00038 20.4 0.0 4.4 7.1 0.0 3.5 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KII87798.1 - 0.00053 19.9 0.4 14 5.8 0.0 5.6 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 KII87798.1 - 0.0023 17.3 0.1 11 5.2 0.0 3.5 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Auts2 PF15336.6 KII87798.1 - 0.0033 17.6 8.2 0.0033 17.6 8.2 2.2 1 1 1 2 2 2 1 Autism susceptibility gene 2 protein Cytochrom_D1 PF02239.16 KII87798.1 - 0.0071 14.9 0.3 0.11 11.1 0.0 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain CENP-F_leu_zip PF10473.9 KII87798.1 - 0.029 14.4 0.9 0.048 13.7 0.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup160 PF11715.8 KII87798.1 - 0.036 12.7 0.2 1 7.9 0.1 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CEP63 PF17045.5 KII87798.1 - 0.088 12.7 1.3 0.15 12.0 1.3 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa ADIP PF11559.8 KII87798.1 - 0.11 12.6 1.2 0.23 11.6 1.2 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KII87798.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KII87798.1 - 0.16 11.2 0.3 0.22 10.7 0.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 KII87798.1 - 0.17 11.3 3.2 0.27 10.7 3.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KII87798.1 - 0.21 10.4 1.9 0.3 9.9 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.32 KII87799.1 - 4.2e-48 160.3 12.3 1.2e-09 38.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87799.1 - 8.3e-13 48.4 0.1 1.4e-05 25.3 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII87799.1 - 1.2e-07 31.1 0.6 0.18 10.8 0.2 5.0 2 2 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KII87799.1 - 5.1e-05 22.1 0.2 3.3 6.2 0.0 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KII87799.1 - 0.00015 20.5 0.9 0.077 11.5 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain DUF5122 PF17164.4 KII87799.1 - 0.00043 20.5 1.6 6.1 7.2 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF5122) beta-propeller WD40_like PF17005.5 KII87799.1 - 0.0091 15.4 0.0 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 WD40-like domain NHL PF01436.21 KII87799.1 - 0.012 15.6 0.2 0.65 10.1 0.0 3.0 3 0 0 3 3 3 0 NHL repeat VID27 PF08553.10 KII87799.1 - 0.013 14.6 0.4 2.9 6.9 0.0 2.8 2 1 0 3 3 3 0 VID27 C-terminal WD40-like domain Peptidase_C13 PF01650.18 KII87800.1 - 4.2e-44 151.0 0.6 5.3e-44 150.7 0.6 1.1 1 0 0 1 1 1 1 Peptidase C13 family HCNGP PF07818.13 KII87801.1 - 3.1e-33 114.3 0.3 4.7e-33 113.7 0.3 1.3 1 0 0 1 1 1 1 HCNGP-like protein DUF1373 PF07117.11 KII87801.1 - 0.018 15.0 1.8 0.026 14.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) MR_MLE_C PF13378.6 KII87803.1 - 7.5e-48 163.0 0.6 3e-46 157.7 0.2 2.8 2 1 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KII87803.1 - 3e-08 33.9 0.0 7.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KII87803.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DnaJ PF00226.31 KII87804.1 - 1.6e-20 72.9 0.7 5e-20 71.4 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 KII87804.1 - 0.1 12.5 0.1 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 A repeated domain in UCH-protein Spore_coat_CotO PF14153.6 KII87804.1 - 2.4 8.0 19.8 1.9 8.4 8.5 2.5 3 0 0 3 3 3 0 Spore coat protein CotO Borrelia_P83 PF05262.11 KII87804.1 - 3 6.3 12.1 4 5.8 12.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 KII87804.1 - 6.6 5.4 6.1 10 4.7 6.1 1.3 1 0 0 1 1 1 0 Presenilin LRIF1 PF15741.5 KII87804.1 - 7.3 5.0 7.1 11 4.3 7.1 1.3 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 ATG101 PF07855.12 KII87805.1 - 2.2e-41 141.4 0.1 2.6e-41 141.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 DSPc PF00782.20 KII87806.1 - 1.1e-27 96.4 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII87806.1 - 0.004 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TraH_2 PF06871.11 KII87807.1 - 0.039 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 TraH_2 DUF2855 PF11017.8 KII87808.1 - 3.2e-105 352.6 0.0 3.7e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Mcp5_PH PF12814.7 KII87810.1 - 7.4e-46 155.2 0.1 1.3e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KII87810.1 - 3.9e-06 27.3 0.0 1.3e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 PH domain ATG16 PF08614.11 KII87810.1 - 0.0003 21.1 13.3 0.0003 21.1 13.3 4.6 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) kleA_kleC PF17383.2 KII87810.1 - 0.97 9.8 13.5 0.51 10.7 0.9 3.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A MAD PF05557.13 KII87810.1 - 2.4 6.4 29.3 0.046 12.1 14.4 3.0 3 0 0 3 3 3 0 Mitotic checkpoint protein Fez1 PF06818.15 KII87810.1 - 5.7 7.3 32.1 0.13 12.7 19.3 3.2 2 1 1 3 3 3 0 Fez1 Lipoprotein_20 PF13942.6 KII87810.1 - 9.4 6.1 13.3 1.9 8.4 7.0 2.5 1 1 1 2 2 2 0 YfhG lipoprotein Sec23_trunk PF04811.15 KII87811.1 - 6.8e-53 179.7 0.0 1.2e-52 178.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KII87811.1 - 5e-25 87.3 0.3 9.4e-25 86.4 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KII87811.1 - 4.4e-19 69.0 0.2 9.3e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KII87811.1 - 1.4e-14 53.8 5.3 3.1e-14 52.7 5.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KII87811.1 - 0.0015 18.4 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Cnn_1N PF07989.11 KII87812.1 - 0.011 15.9 0.1 0.011 15.9 0.1 5.3 5 0 0 5 5 5 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 KII87812.1 - 0.012 15.6 5.8 0.012 15.6 5.8 6.5 4 2 3 7 7 7 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KII87812.1 - 0.12 12.3 53.7 0.87 9.6 9.8 5.2 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KII87812.1 - 0.76 10.3 65.9 0.15 12.6 15.3 5.2 2 1 3 5 5 5 0 Apg6 coiled-coil region Spc7 PF08317.11 KII87812.1 - 1.1 8.1 59.5 0.12 11.2 14.1 5.0 2 1 3 5 5 5 0 Spc7 kinetochore protein DDE_3 PF13358.6 KII87813.1 - 3.1e-05 23.8 0.0 0.0075 16.0 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_23 PF13384.6 KII87813.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain IGR PF09597.10 KII87815.1 - 4.1e-20 71.6 0.0 6.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase_fungal PF17667.1 KII87816.1 - 2e-10 40.0 0.1 2.2e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII87816.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII87817.1 - 0.0026 16.6 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KII87818.1 - 0.00019 20.4 0.0 0.00026 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF3400 PF11880.8 KII87818.1 - 0.029 13.9 0.3 0.056 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) GMC_oxred_N PF00732.19 KII87819.1 - 2.1e-73 247.3 0.0 2.7e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII87819.1 - 2e-37 128.9 0.0 3.3e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KII87819.1 - 5.2e-05 23.4 0.1 0.00023 21.3 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII87819.1 - 0.00039 19.6 0.2 0.053 12.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KII87819.1 - 0.00048 19.8 0.1 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII87819.1 - 0.0011 18.1 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII87819.1 - 0.0019 17.5 0.0 0.0054 16.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII87819.1 - 0.0068 16.9 0.4 0.04 14.5 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII87819.1 - 0.033 12.9 0.1 0.098 11.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 KII87819.1 - 0.065 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KII87819.1 - 0.072 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 KII87819.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PDEase_I PF00233.19 KII87820.1 - 1.5e-51 175.4 0.0 3.1e-51 174.4 0.0 1.5 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KII87820.1 - 0.03 14.5 0.1 0.066 13.4 0.1 1.6 1 0 0 1 1 1 0 HD domain Methyltransf_16 PF10294.9 KII87822.1 - 4.2e-09 36.4 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase vMSA PF00695.19 KII87824.1 - 1.7 7.6 7.8 3.6 6.6 7.8 1.4 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus TM231 PF10149.9 KII87825.1 - 0.015 14.6 0.4 0.017 14.5 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Cpta_toxin PF07254.12 KII87825.1 - 0.054 13.5 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system DUF273 PF03314.14 KII87826.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Asp_protease_2 PF13650.6 KII87828.1 - 4.4e-06 27.3 0.0 1.8e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KII87828.1 - 1.7e-05 25.3 0.0 5.4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4596 PF15363.6 KII87828.1 - 1.1 9.6 3.3 1.3 9.3 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Evr1_Alr PF04777.13 KII87828.1 - 1.1 9.8 4.3 28 5.3 1.4 2.3 2 0 0 2 2 2 0 Erv1 / Alr family DDE_1 PF03184.19 KII87829.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DpnII-MboI PF18742.1 KII87829.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 REase_DpnII-MboI BTB PF00651.31 KII87830.1 - 8.3e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HTH_30 PF13556.6 KII87831.1 - 0.0023 17.7 0.9 0.0035 17.1 0.9 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain zf-H2C2_5 PF13909.6 KII87831.1 - 1.8 8.4 4.9 1.8 8.4 2.9 1.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF1648 PF07853.11 KII87832.1 - 0.0055 16.3 0.0 3.3 7.4 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF1648) Cys_Met_Meta_PP PF01053.20 KII87833.1 - 2e-08 33.2 0.0 2.2e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Malate_synthase PF01274.22 KII87834.1 - 5.1e-76 256.0 0.0 6.4e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase_fungal PF17667.1 KII87841.1 - 1.7e-11 43.6 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KII87841.1 - 0.015 14.9 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 RIO1 family DUF5086 PF16985.5 KII87841.1 - 0.086 12.7 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5086) ROS_MUCR PF05443.11 KII87841.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Amidohydro_3 PF07969.11 KII87842.1 - 0.0015 18.1 0.2 0.29 10.5 0.1 2.4 1 1 1 2 2 2 2 Amidohydrolase family MutS_V PF00488.21 KII87843.1 - 3e-64 216.5 0.1 5.4e-64 215.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KII87843.1 - 3.1e-35 122.1 0.0 7.5e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KII87843.1 - 1.5e-33 115.4 0.1 3e-33 114.4 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KII87843.1 - 1.4e-09 38.4 0.1 5.7e-09 36.4 0.1 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KII87843.1 - 2.9e-05 24.3 0.0 7.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV Glyco_hydro_16 PF00722.21 KII87844.1 - 1.4e-40 138.7 4.0 2e-40 138.1 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KII87844.1 - 1.7 9.2 17.4 0.2 12.1 12.7 1.9 2 0 0 2 2 2 0 Chitin recognition protein DUF667 PF05018.13 KII87845.1 - 8.3e-20 71.3 0.0 2.2e-10 40.5 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) DUF5566 PF17721.1 KII87845.1 - 1.8 8.7 6.2 33 4.6 4.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5566) Dioxygenase_C PF00775.21 KII87846.1 - 1.2e-45 155.2 0.0 1.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KII87846.1 - 1.8e-28 98.2 0.0 5.1e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KII87846.1 - 0.12 12.6 0.0 0.89 9.9 0.0 2.3 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain XPG_N PF00752.17 KII87847.1 - 4.5e-26 91.3 0.0 8.9e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KII87847.1 - 3.7e-23 81.7 0.0 8.5e-23 80.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KII87847.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KII87847.1 - 1.4e-05 25.6 0.0 4.3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 KII87847.1 - 0.0017 18.3 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat HHH_5 PF14520.6 KII87847.1 - 0.0025 18.4 0.0 0.0083 16.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain TPR_1 PF00515.28 KII87847.1 - 0.0049 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII87847.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HHH PF00633.23 KII87847.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 KII87847.1 - 0.019 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_21 PF09976.9 KII87847.1 - 0.029 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 KII87847.1 - 0.25 12.3 1.5 0.39 11.7 0.2 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TMA7 PF09072.10 KII87848.1 - 0.07 14.0 0.2 0.55 11.1 0.0 2.5 2 0 0 2 2 2 0 Translation machinery associated TMA7 zf-C2H2_4 PF13894.6 KII87849.1 - 1.9e-06 28.2 16.1 6.6e-05 23.4 0.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KII87849.1 - 2.8e-06 27.5 9.5 0.00039 20.7 0.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII87849.1 - 8.1e-06 26.0 14.7 3.5e-05 24.0 0.3 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KII87849.1 - 0.00016 22.0 6.4 0.00035 20.9 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII87849.1 - 0.00024 21.3 3.0 0.0012 19.1 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KII87849.1 - 0.49 10.4 0.2 0.49 10.4 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger PIG-P PF08510.12 KII87850.1 - 6.6e-35 119.7 1.1 7.7e-35 119.4 1.1 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 KII87850.1 - 0.0034 17.7 6.3 0.0073 16.6 6.3 1.5 1 1 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) 5-FTHF_cyc-lig PF01812.20 KII87851.1 - 9.7e-39 133.1 0.0 1.1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rad51 PF08423.11 KII87852.1 - 1.4e-10 40.8 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KII87852.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 KaiC RecA PF00154.21 KII87852.1 - 0.0019 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KII87852.1 - 0.02 14.2 0.0 0.96 8.7 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KII87852.1 - 0.038 13.7 0.6 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein RRM_1 PF00076.22 KII87853.1 - 3e-21 75.0 0.0 4e-09 36.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII87853.1 - 0.0068 16.0 0.0 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 KII87854.1 - 1.8e-59 201.7 0.0 2.6e-58 197.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sec2p PF06428.11 KII87856.1 - 5e-13 48.8 10.7 5e-13 48.8 10.7 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Pheromone PF08015.11 KII87856.1 - 0.12 13.4 0.4 0.12 13.4 0.4 7.4 2 1 2 4 4 4 0 Fungal mating-type pheromone Herpes_UL6 PF01763.16 KII87856.1 - 1.2 7.5 6.0 0.6 8.6 3.7 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.15 KII87856.1 - 3.4 7.5 7.1 5.5 6.8 0.3 2.6 2 0 0 2 2 2 0 Septum formation initiator CC2-LZ PF16516.5 KII87856.1 - 6.1 7.3 17.9 2.2 8.7 5.2 3.5 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DFP PF04127.15 KII87857.1 - 2.6e-20 73.1 0.0 6.3e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein GATase PF00117.28 KII87858.1 - 1.3e-09 38.2 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Phosphorylase PF00343.20 KII87858.1 - 0.088 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase GATase_3 PF07685.14 KII87858.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SIS PF01380.22 KII87860.1 - 1.4e-61 206.1 0.1 3.6e-33 114.2 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KII87860.1 - 4.8e-15 56.0 0.0 1.8e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KII87860.1 - 1.5e-10 41.0 0.0 6.1e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KII87860.1 - 0.00046 19.2 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KII87860.1 - 0.14 12.2 0.0 0.54 10.3 0.0 2.0 1 1 1 2 2 2 0 SIS domain Egh16-like PF11327.8 KII87861.1 - 3.7e-07 30.8 3.1 5.2e-07 30.3 3.1 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor GidB PF02527.15 KII87863.1 - 0.055 12.8 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G p450 PF00067.22 KII87864.1 - 2.3e-62 211.3 0.0 1e-61 209.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF302 PF03625.14 KII87867.1 - 9.7e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 Formyl_trans_N PF00551.19 KII87868.1 - 8.2e-20 71.3 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KII87868.1 - 5.1e-09 36.3 0.0 8.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Stn1 PF10451.9 KII87869.1 - 1.7e-08 33.7 0.5 0.00024 20.2 0.1 2.5 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KII87869.1 - 4.2e-05 23.4 0.1 0.00011 22.1 0.1 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Unstab_antitox PF09720.10 KII87870.1 - 0.029 14.4 0.5 0.062 13.4 0.5 1.6 1 0 0 1 1 1 0 Putative addiction module component TENA_THI-4 PF03070.16 KII87872.1 - 9.6e-11 41.9 0.1 3.3e-10 40.1 0.1 1.7 1 1 0 1 1 1 1 TENA/THI-4/PQQC family RRM_1 PF00076.22 KII87873.1 - 4.8e-11 42.3 0.0 7.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KII87873.1 - 1.9e-09 37.9 0.6 4.6e-09 36.7 0.6 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 KII87874.1 - 1e-30 105.2 20.9 0.00011 22.9 0.5 10.4 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87874.1 - 3.6e-19 68.8 0.1 2.9e-07 30.7 0.0 5.9 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII87874.1 - 0.00015 20.9 0.6 0.23 10.4 0.0 4.2 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KII87874.1 - 0.00045 18.4 0.0 0.47 8.4 0.0 2.3 2 0 0 2 2 2 2 IKI3 family RAB3GAP2_N PF14655.6 KII87874.1 - 0.0013 18.1 0.1 0.045 13.0 0.0 2.9 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 KII87874.1 - 0.0026 17.1 0.5 5.2 6.3 0.0 3.3 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 KII87874.1 - 0.0097 16.4 4.2 9.3 6.9 0.0 5.7 6 0 0 6 6 6 1 PQQ-like domain PD40 PF07676.12 KII87874.1 - 0.011 15.6 2.5 4 7.5 0.7 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KII87874.1 - 0.011 14.4 2.4 0.28 9.8 1.3 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ PF01011.21 KII87874.1 - 0.12 12.4 1.1 21 5.2 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat Mad3_BUB1_I PF08311.12 KII87875.1 - 3.9e-36 123.8 0.2 5.7e-36 123.2 0.2 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 KII87875.1 - 0.038 14.1 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein ECH_1 PF00378.20 KII87875.1 - 0.056 12.7 0.1 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase MMS1_N PF10433.9 KII87876.1 - 1.4e-51 175.6 0.0 2.5e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KII87876.1 - 2.2e-47 161.9 0.0 5.1e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region Rad52_Rad22 PF04098.15 KII87877.1 - 3.5e-57 192.6 0.0 4.1e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MFS_1 PF07690.16 KII87878.1 - 1.7e-32 112.8 25.5 2.6e-32 112.1 25.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2838 PF10998.8 KII87878.1 - 0.055 13.7 0.4 0.19 12.0 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) DUF308 PF03729.13 KII87878.1 - 0.94 9.8 9.9 0.64 10.4 5.4 2.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Cupin_1 PF00190.22 KII87879.1 - 5e-42 143.1 0.2 1.1e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KII87879.1 - 5.3e-26 90.1 0.5 7.6e-12 44.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KII87879.1 - 6e-07 29.1 0.1 0.0063 16.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KII87879.1 - 0.00069 19.5 0.0 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KII87879.1 - 0.0032 17.4 0.3 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.12 KII87879.1 - 0.017 14.6 0.0 5.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein 3-HAO PF06052.12 KII87879.1 - 0.017 14.7 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.8 KII87879.1 - 0.053 13.7 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Mif2/CENP-C like RRM_1 PF00076.22 KII87881.1 - 9.6e-38 127.9 0.0 1.8e-19 69.3 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KII87881.1 - 9.1e-10 38.6 3.0 0.00021 21.4 0.1 3.3 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KII87881.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KII87881.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.10 KII87883.1 - 1.1e-27 96.1 0.6 1.8e-27 95.4 0.6 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KII87883.1 - 6.3e-20 71.5 0.0 9.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII87883.1 - 2.1e-18 66.8 0.0 4.5e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII87883.1 - 2.9e-17 63.1 0.1 7.8e-17 61.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KII87883.1 - 7.7e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KII87883.1 - 1e-11 45.4 0.1 2.9e-11 44.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII87883.1 - 4.1e-10 39.8 0.0 6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII87883.1 - 6.3e-08 32.2 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KII87883.1 - 4.5e-05 23.3 0.0 6.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KII87883.1 - 0.00038 20.0 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 KII87883.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KII87883.1 - 0.0047 17.9 0.0 0.066 14.2 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 KII87883.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 KII87883.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KII87883.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KII87883.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 KII87883.1 - 0.023 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.10 KII87883.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 KII87883.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Mitoc_mL59 PF18126.1 KII87884.1 - 2.6e-36 124.8 8.2 1.3e-35 122.5 8.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 WD40 PF00400.32 KII87886.1 - 1e-11 45.2 3.5 1.9e-06 28.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 KII87886.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF1699 PF08004.11 KII87888.1 - 0.079 12.6 0.2 0.93 9.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1699) F-box PF00646.33 KII87889.1 - 6.4e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII87889.1 - 0.0027 17.6 0.3 0.0081 16.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 KII87890.1 - 0.00018 22.2 0.0 6.3 7.9 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3248 PF11609.8 KII87890.1 - 0.02 14.8 0.1 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) ANAPC4_WD40 PF12894.7 KII87890.1 - 0.03 14.6 0.0 6.3 7.2 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Cas_CXXC_CXXC PF09706.10 KII87890.1 - 0.13 12.5 1.5 0.31 11.3 1.5 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Transposase_21 PF02992.14 KII87891.1 - 2.7e-06 26.8 0.0 5.4e-06 25.8 0.0 1.4 2 0 0 2 2 2 1 Transposase family tnp2 DUF1258 PF06869.12 KII87891.1 - 0.06 12.8 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF1593 PF07632.11 KII87892.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) FRP PF18032.1 KII87892.1 - 0.11 13.1 0.1 1.3 9.6 0.0 2.0 1 1 1 2 2 2 0 Photoprotection regulator fluorescence recovery protein Shugoshin_N PF07558.11 KII87893.1 - 0.87 9.5 7.2 7.7 6.5 0.3 4.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ATG11 PF10377.9 KII87895.1 - 4e-32 111.0 0.0 1.7e-31 108.9 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein 11 Sugar_tr PF00083.24 KII87896.1 - 2.4e-86 290.4 20.4 2.7e-86 290.2 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII87896.1 - 9.2e-26 90.6 57.0 6.3e-23 81.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PH_9 PF15410.6 KII87897.1 - 0.00019 21.8 0.0 0.00023 21.5 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KII87897.1 - 0.0022 18.5 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 PH domain Metallophos PF00149.28 KII87898.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KII87898.1 - 4.8e-22 78.1 0.2 1.1e-21 77.0 0.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain F-box PF00646.33 KII87899.1 - 0.011 15.6 0.4 0.038 13.9 0.4 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 KII87899.1 - 0.96 9.4 4.5 0.74 9.8 2.1 2.1 2 0 0 2 2 2 0 F-box-like DUF2156 PF09924.9 KII87900.1 - 6.6e-13 48.3 0.0 1.3e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Gly_transf_sug PF04488.15 KII87901.1 - 1.6e-06 28.7 0.0 2.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KII87901.1 - 0.035 13.5 0.3 0.051 12.9 0.3 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein F-box-like PF12937.7 KII87902.1 - 0.0012 18.7 0.3 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII87903.1 - 0.0035 17.2 0.1 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KII87903.1 - 0.0078 16.0 2.8 0.072 12.9 0.0 3.6 4 0 0 4 4 4 1 Leucine rich repeat F-box PF00646.33 KII87903.1 - 0.012 15.4 0.1 0.1 12.5 0.0 2.7 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 KII87903.1 - 0.22 12.2 5.1 9.6 7.2 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat DUF1769 PF08588.10 KII87904.1 - 2e-23 82.3 0.2 4.4e-23 81.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Autophagy_C PF10381.9 KII87904.1 - 0.034 13.7 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Apt1 PF10351.9 KII87904.1 - 0.23 10.3 3.3 0.27 10.1 3.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 KII87904.1 - 1.2 8.4 5.2 1.5 8.1 5.2 1.1 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 KII87906.1 - 0.0015 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KII87906.1 - 0.019 15.4 2.6 5.4 8.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KII87906.1 - 0.03 14.1 0.2 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat F-box PF00646.33 KII87906.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 KII87907.1 - 3.8e-45 154.5 0.0 5e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SMC_N PF02463.19 KII87909.1 - 1.4e-27 96.6 5.3 2.6e-27 95.7 5.3 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII87909.1 - 1.1e-12 48.9 29.1 2e-09 38.2 29.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KII87909.1 - 4.4e-10 39.8 5.6 6.7e-10 39.2 5.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KII87909.1 - 7e-08 32.1 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KII87909.1 - 8.9e-08 32.3 0.1 1.9e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 KII87909.1 - 0.0036 16.6 4.9 0.0053 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) ABC_tran PF00005.27 KII87909.1 - 0.074 13.6 7.3 2.2 8.8 7.3 2.6 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KII87909.1 - 0.71 9.8 3.4 4 7.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ZapD PF07072.11 KII87909.1 - 1.1 9.0 10.6 0.32 10.7 3.2 2.5 1 1 1 2 2 2 0 Cell division protein Spc7 PF08317.11 KII87909.1 - 1.7 7.4 23.2 2.3 7.0 21.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 KII87909.1 - 3.9 7.8 11.0 52 4.2 8.7 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1664 PF07889.12 KII87909.1 - 5.7 7.0 8.7 3.7 7.6 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 KII87910.1 - 9.4e-20 70.2 0.1 1.6e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF3042 PF11240.8 KII87910.1 - 0.057 13.4 0.8 0.15 12.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) ESP PF16590.5 KII87910.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Cnd3 PF12719.7 KII87912.1 - 2.5e-79 266.6 3.7 8.6e-79 264.8 3.7 2.0 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KII87912.1 - 1.3e-05 25.5 6.2 0.0088 16.4 0.3 5.3 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 KII87912.1 - 0.00017 21.5 5.2 0.083 13.2 0.2 5.4 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 KII87912.1 - 0.00094 18.4 2.4 0.015 14.5 0.0 3.4 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KII87912.1 - 0.023 14.9 0.1 0.27 11.4 0.0 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KII87912.1 - 0.063 13.3 2.8 2.6 8.0 0.0 3.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Sec23_trunk PF04811.15 KII87913.1 - 1.3e-73 247.5 0.0 2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KII87913.1 - 4.6e-30 104.2 0.3 9.6e-30 103.2 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KII87913.1 - 8.5e-26 89.8 0.1 2e-25 88.6 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KII87913.1 - 2e-15 56.5 7.0 3.8e-15 55.7 7.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KII87913.1 - 3.7e-14 52.4 0.0 2.2e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KII87913.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OPT PF03169.15 KII87915.1 - 2.3e-147 492.3 53.0 2.7e-147 492.1 53.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NMD3 PF04981.13 KII87916.1 - 5.3e-80 268.4 0.4 7e-80 268.0 0.4 1.2 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 KII87916.1 - 0.014 15.3 2.6 0.019 14.8 0.7 2.2 2 0 0 2 2 2 0 NinF protein DZR PF12773.7 KII87916.1 - 0.066 13.3 7.1 1.8 8.7 7.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon TT_ORF2 PF02957.15 KII87916.1 - 0.15 12.9 5.4 1.8 9.5 0.0 2.5 2 0 0 2 2 2 0 TT viral ORF2 HypA PF01155.19 KII87916.1 - 0.59 10.2 5.7 0.85 9.7 0.5 2.8 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rpr2 PF04032.16 KII87916.1 - 1.3 9.3 3.3 14 6.1 0.2 3.0 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Sdh5 PF03937.16 KII87920.1 - 4.1e-28 97.1 1.9 5.5e-28 96.7 1.9 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase adh_short_C2 PF13561.6 KII87921.1 - 2.2e-51 174.7 0.7 2.8e-51 174.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII87921.1 - 4.3e-40 137.3 0.1 5.9e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII87921.1 - 2.5e-14 53.6 0.6 3.1e-14 53.3 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII87921.1 - 0.0061 16.1 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII87921.1 - 0.093 11.7 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DEAD PF00270.29 KII87922.1 - 4.4e-43 147.1 0.1 6.6e-43 146.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII87922.1 - 3e-27 95.2 0.7 1.4e-26 93.0 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KII87922.1 - 0.03 13.7 0.2 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_3 PF13302.7 KII87923.1 - 7.5e-15 55.8 0.3 2.7e-13 50.8 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87923.1 - 1.8e-11 44.3 0.0 2.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII87923.1 - 4.1e-06 26.5 0.2 0.00027 20.6 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII87923.1 - 3.4e-05 24.0 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII87923.1 - 0.00027 21.3 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HAUS6_N PF14661.6 KII87924.1 - 0.023 14.3 1.2 0.034 13.7 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase_fungal PF17667.1 KII87926.1 - 0.084 11.6 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_fungal PF17667.1 KII87927.1 - 2.5e-05 23.3 0.1 2.6e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_3 PF13302.7 KII87928.1 - 1.6e-16 61.2 0.0 1.9e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87928.1 - 4.5e-13 49.5 0.0 5.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII87928.1 - 0.00057 19.6 0.1 0.0075 16.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII87928.1 - 0.0016 18.8 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII87928.1 - 0.0028 17.6 0.0 0.013 15.5 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KII87928.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII87929.1 - 3.5e-11 43.9 0.1 4.5e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87929.1 - 2.8e-10 40.5 0.1 3.6e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII87929.1 - 2.4e-06 27.4 0.1 3.2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KII87929.1 - 1.4e-05 24.8 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII87929.1 - 1.4e-05 25.4 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII87929.1 - 5.7e-05 23.0 0.0 6.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII87929.1 - 0.00073 19.7 0.0 0.00085 19.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII87930.1 - 4.3e-17 63.1 0.0 5.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87930.1 - 1.3e-10 41.6 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII87930.1 - 0.00058 19.6 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII87931.1 - 2e-08 35.0 0.0 2.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87931.1 - 1.8e-06 28.2 0.9 2.6e-06 27.6 0.9 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII87931.1 - 0.0028 17.3 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII87931.1 - 0.1 12.7 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain KH_4 PF13083.6 KII87931.1 - 0.15 12.0 0.2 0.21 11.5 0.2 1.2 1 0 0 1 1 1 0 KH domain USP8_interact PF08941.10 KII87932.1 - 0.055 13.3 2.5 0.26 11.1 0.0 2.1 1 1 1 2 2 2 0 USP8 interacting AAA_13 PF13166.6 KII87932.1 - 2.6 6.6 7.4 3.2 6.3 7.4 1.0 1 0 0 1 1 1 0 AAA domain DUF2797 PF10977.8 KII87932.1 - 4.7 7.0 7.9 6.1 6.7 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Acetyltransf_3 PF13302.7 KII87933.1 - 0.0094 16.6 0.0 0.014 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII87934.1 - 1.1e-17 65.0 0.0 1.4e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII87934.1 - 7.7e-11 42.3 0.0 1.5e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII87934.1 - 7.1e-08 32.3 0.6 8.1e-07 28.8 0.6 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII87934.1 - 0.0048 17.3 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII87934.1 - 0.078 13.1 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MAPEG PF01124.18 KII87936.1 - 1.4e-16 60.6 2.1 1.7e-16 60.3 2.1 1.1 1 0 0 1 1 1 1 MAPEG family Ion_trans PF00520.31 KII87936.1 - 0.0037 16.5 0.2 0.0053 16.0 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein Transket_pyr PF02779.24 KII87937.1 - 1e-57 194.7 0.0 1.6e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KII87937.1 - 4.3e-42 143.4 0.0 7.8e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KII87937.1 - 5.4e-36 124.1 0.0 9.8e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component HAD PF12710.7 KII87938.1 - 6.1e-21 75.7 0.0 8.5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII87938.1 - 2.2e-05 24.9 0.7 0.00078 19.8 0.7 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KII87938.1 - 3.4e-05 23.5 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 KII87938.1 - 0.0053 16.2 0.0 0.0098 15.3 0.0 1.4 2 0 0 2 2 2 1 Putative Phosphatase SpoU_sub_bind PF08032.12 KII87938.1 - 0.026 14.8 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DEAD PF00270.29 KII87939.1 - 9.5e-17 61.3 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII87939.1 - 1.7e-10 41.1 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII87939.1 - 2e-05 24.9 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldo_ket_red PF00248.21 KII87940.1 - 5e-46 157.2 0.1 4e-44 151.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Bac_DNA_binding PF00216.21 KII87940.1 - 0.18 12.0 0.2 15 5.8 0.1 2.8 3 0 0 3 3 3 0 Bacterial DNA-binding protein Ribosomal_S13_N PF08069.12 KII87942.1 - 1.1e-31 108.6 0.1 2.5e-31 107.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KII87942.1 - 5.7e-15 55.3 0.5 7.3e-15 55.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KII87942.1 - 0.021 14.7 0.1 0.031 14.2 0.1 1.6 1 1 0 1 1 1 0 'Paired box' domain HTH_32 PF13565.6 KII87942.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_S6e PF01092.19 KII87943.1 - 1.7e-57 192.8 0.5 2.7e-57 192.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e DUF4381 PF14316.6 KII87944.1 - 0.074 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MGC-24 PF05283.11 KII87945.1 - 0.016 15.6 0.3 0.016 15.6 0.3 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin GH115_C PF17829.1 KII87945.1 - 0.036 13.9 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain Herpes_gE PF02480.16 KII87945.1 - 0.054 12.2 0.1 0.078 11.7 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GLEYA PF10528.9 KII87945.1 - 0.46 10.9 2.2 5.8 7.4 0.4 2.6 2 0 0 2 2 2 0 GLEYA domain Vma12 PF11712.8 KII87946.1 - 2.2 8.3 10.1 0.15 12.1 1.4 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Herpes_LMP1 PF05297.11 KII87946.1 - 3.2 6.9 9.2 4.7 6.3 9.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) IBR PF01485.21 KII87947.1 - 1.9e-08 34.4 34.2 3.5e-06 27.1 7.5 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain MFS_1 PF07690.16 KII87948.1 - 1.7e-39 135.7 25.7 1.7e-39 135.7 25.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII87948.1 - 4.1e-12 45.7 6.3 4.1e-12 45.7 6.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.11 KII87948.1 - 2.6 8.2 6.4 1 9.6 0.8 2.9 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Aldo_ket_red PF00248.21 KII87949.1 - 4.2e-73 246.1 0.0 4.8e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII87950.1 - 6.3e-72 242.3 0.0 7.1e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMG_box PF00505.19 KII87953.1 - 2e-11 44.1 0.5 3.7e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII87953.1 - 0.00032 21.2 0.1 0.0018 18.9 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain YcbB PF08664.10 KII87954.1 - 8.8 6.4 7.1 3.7 7.6 2.3 2.2 2 0 0 2 2 2 0 YcbB domain adh_short PF00106.25 KII87958.1 - 8.7e-13 48.2 0.0 1.4e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87958.1 - 4.4e-10 39.5 0.0 6.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87958.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KII87958.1 - 0.00095 19.4 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Peptidase_C14 PF00656.22 KII87959.1 - 1.7e-23 83.9 0.0 2.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KII87959.1 - 0.023 14.7 0.0 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain DUF4599 PF15371.6 KII87959.1 - 0.033 14.7 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) WD40 PF00400.32 KII87960.1 - 2e-07 31.6 0.3 4.5e-05 24.1 0.4 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87960.1 - 0.0024 18.2 0.0 2.3 8.5 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C14 PF00656.22 KII87962.1 - 6.1e-24 85.3 0.0 9.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.32 KII87964.1 - 5.9e-20 71.2 10.8 2.1e-07 31.5 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII87964.1 - 7.1e-07 29.4 0.1 0.066 13.5 0.0 4.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1961 PF09224.11 KII87964.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) BBS2_N PF14781.6 KII87964.1 - 0.06 13.2 0.0 33 4.4 0.0 3.6 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Peptidase_C14 PF00656.22 KII87965.1 - 3.3e-30 105.8 0.0 1.1e-29 104.1 0.0 1.7 1 1 0 1 1 1 1 Caspase domain PaaB PF06243.11 KII87966.1 - 0.18 12.1 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Phenylacetic acid degradation B adh_short PF00106.25 KII87967.1 - 4.7e-11 42.5 0.0 1.3e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87967.1 - 9.9e-09 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87967.1 - 5.1e-06 26.5 0.0 8.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KII87967.1 - 0.0067 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KII87968.1 - 3.6e-10 39.6 0.0 9.1e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII87968.1 - 6.4e-08 32.4 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII87968.1 - 6.7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KII87968.1 - 0.00054 20.2 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain CASP_C PF08172.12 KII87969.1 - 0.18 11.1 4.1 0.31 10.3 4.1 1.3 1 0 0 1 1 1 0 CASP C terminal tRNA-synt_1d PF00750.19 KII87970.1 - 2.7e-100 335.7 2.3 3.5e-100 335.3 2.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KII87970.1 - 3.7e-19 69.1 0.0 8.1e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain bZIP_1 PF00170.21 KII87971.1 - 1.1e-08 35.1 16.6 2e-08 34.2 8.7 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KII87971.1 - 4.5e-08 33.1 13.0 4.5e-08 33.1 13.0 2.7 2 1 0 3 3 3 1 Basic region leucine zipper HAP1_N PF04849.13 KII87971.1 - 0.063 12.5 4.3 0.13 11.4 4.3 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF724 PF05266.14 KII87971.1 - 0.065 13.1 6.6 0.1 12.4 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 KII87971.1 - 0.088 13.1 2.2 0.78 10.1 0.1 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 KII87971.1 - 0.16 12.5 13.8 0.41 11.2 13.3 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.6 KII87971.1 - 0.19 11.1 4.3 0.92 8.8 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5384 PF17358.2 KII87971.1 - 0.35 10.9 17.3 0.61 10.1 17.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) ADIP PF11559.8 KII87971.1 - 2.7 8.1 11.3 4 7.5 10.5 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KII87971.1 - 9.8 6.0 7.7 12 5.7 1.3 2.5 2 1 0 2 2 2 0 Septum formation initiator Dimer_Tnp_hAT PF05699.14 KII87972.1 - 6.6e-08 32.2 0.2 8.5e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Metallophos PF00149.28 KII87973.1 - 6.9e-09 36.5 0.0 9.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII87973.1 - 8e-07 29.4 0.0 9.8e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MIOX PF05153.15 KII87974.1 - 1.7e-125 417.6 0.8 2.1e-125 417.3 0.8 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase Cytochrom_C_2 PF01322.20 KII87974.1 - 0.007 17.3 1.4 0.013 16.4 1.4 1.4 1 0 0 1 1 1 1 Cytochrome C' HD PF01966.22 KII87974.1 - 0.086 13.1 0.0 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 HD domain DUF349 PF03993.12 KII87974.1 - 0.17 12.2 3.3 0.12 12.7 1.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Aldo_ket_red PF00248.21 KII87975.1 - 8.1e-51 173.0 0.0 1.1e-48 165.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF478 PF04334.12 KII87976.1 - 0.034 14.2 0.2 0.041 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF478) DivIC PF04977.15 KII87977.1 - 0.23 11.3 6.9 0.21 11.4 2.4 2.4 2 1 1 3 3 3 0 Septum formation initiator UPF0220 PF05255.11 KII87978.1 - 3.9e-55 185.9 0.1 4.8e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Aldo_ket_red PF00248.21 KII87981.1 - 2.9e-75 253.2 0.0 3.4e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KII87983.1 - 2.4e-47 161.6 57.4 8.1e-45 153.3 56.5 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII87983.1 - 1.9e-08 33.6 15.4 1.9e-08 33.6 15.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3611 PF12263.8 KII87983.1 - 0.0088 16.0 3.6 0.0088 16.0 3.6 3.8 4 1 1 5 5 5 2 Protein of unknown function (DUF3611) SF3b1 PF08920.10 KII87984.1 - 3.3 8.2 6.6 1.2 9.6 0.2 2.4 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 HMG_box PF00505.19 KII87986.1 - 2e-09 37.7 0.3 5e-09 36.5 0.3 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII87986.1 - 0.017 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain DUF2083 PF09856.9 KII87989.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) HMG_box PF00505.19 KII87993.1 - 3.3e-09 37.0 6.1 1.7e-08 34.7 6.1 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII87993.1 - 6.4e-08 33.1 3.3 1.3e-07 32.1 3.3 1.4 1 0 0 1 1 1 1 HMG-box domain RCC1 PF00415.18 KII87996.1 - 2.6e-52 175.2 15.6 2.5e-09 37.6 0.0 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII87996.1 - 8.2e-31 105.2 43.3 1.5e-07 31.0 0.3 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.21 KII87997.1 - 2.8e-72 243.4 0.0 3.4e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII87998.1 - 3.5e-72 243.1 0.1 4.1e-72 242.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transposase_mut PF00872.18 KII87998.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family AA_permease_2 PF13520.6 KII87999.1 - 7.7e-81 272.1 30.3 9.8e-81 271.7 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 KII88000.1 - 1.5e-14 54.3 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII88000.1 - 3.1e-10 40.1 0.1 3.6e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII88000.1 - 1.9e-08 34.6 0.0 2.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII88000.1 - 3.7e-06 26.8 0.1 6.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KII88000.1 - 0.00017 21.1 0.1 0.00019 21.0 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KII88000.1 - 0.0093 16.0 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KII88000.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PAS_8 PF13188.7 KII88000.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 PAS domain PanZ PF12568.8 KII88000.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ SLIDE PF09111.10 KII88001.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 SLIDE FANCD2OS PF15124.6 KII88002.1 - 0.21 11.8 3.3 6.8 6.9 0.2 2.9 3 0 0 3 3 3 0 FANCD2 opposite strand protein Pro-kuma_activ PF09286.11 KII88003.1 - 6.4e-41 140.0 0.0 3.5e-40 137.6 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Cellulase PF00150.18 KII88004.1 - 8.4e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.18 KII88009.1 - 3.5e-16 59.1 0.2 6.4e-16 58.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII88009.1 - 7.9e-06 25.9 11.1 1.3e-05 25.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCAT PF02450.15 KII88010.1 - 9.1e-05 21.8 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase MIR PF02815.19 KII88012.1 - 1.8e-17 63.8 1.4 1.2e-15 57.9 0.4 2.6 1 1 1 2 2 2 2 MIR domain PGM_PMM_II PF02879.16 KII88012.1 - 1e-05 26.1 0.0 2.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II KLRAQ PF10205.9 KII88019.1 - 0.0036 17.5 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein CorC_HlyC PF03471.17 KII88019.1 - 0.024 14.7 0.2 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Transporter associated domain PBP-Tp47_a PF14889.6 KII88019.1 - 0.025 14.2 0.7 7.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a DUF3077 PF11275.8 KII88019.1 - 0.096 12.9 0.0 27 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) adh_short PF00106.25 KII88022.1 - 2e-13 50.2 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII88022.1 - 4e-09 36.4 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88022.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KII88022.1 - 0.0048 17.2 0.0 0.008 16.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KII88023.1 - 7.7e-31 107.1 0.1 4.3e-25 88.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII88023.1 - 9.9e-21 74.4 0.5 4.2e-19 69.0 0.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88023.1 - 9.6e-10 38.7 0.2 2e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII88023.1 - 9.9e-08 31.7 0.2 1.6e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII88023.1 - 0.0029 17.0 0.1 0.0034 16.8 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KII88023.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2807 PF10988.8 KII88023.1 - 0.046 13.5 0.3 0.08 12.7 0.3 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Shikimate_DH PF01488.20 KII88023.1 - 0.067 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KII88024.1 - 1.1e-30 106.6 0.0 6.3e-25 87.8 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII88024.1 - 2e-19 70.1 0.1 1.9e-16 60.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88024.1 - 4.7e-09 36.4 0.1 7.5e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII88024.1 - 7.2e-07 28.9 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII88024.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KII88024.1 - 0.0048 17.1 0.0 0.014 15.7 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 KII88024.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KII88024.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DDE_Tnp_4 PF13359.6 KII88027.1 - 2.9e-18 66.0 0.0 4.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 KII88027.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain UPF0242 PF06785.11 KII88028.1 - 0.35 10.9 3.0 0.18 11.9 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RRN3 PF05327.11 KII88028.1 - 0.5 8.9 2.6 0.71 8.3 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cauli_VI PF01693.16 KII88029.1 - 4.8e-22 78.0 2.2 2.3e-14 53.4 0.6 2.2 2 0 0 2 2 2 2 Caulimovirus viroplasmin KTSC PF13619.6 KII88029.1 - 0.0014 18.4 0.1 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 KTSC domain DUF4241 PF14025.6 KII88029.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) 2OG-FeII_Oxy_3 PF13640.6 KII88030.1 - 0.0063 17.4 0.0 0.01 16.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 KII88031.1 - 1.3e-59 201.5 0.0 2e-59 200.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII88031.1 - 8.8e-40 135.2 0.0 1.6e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII88031.1 - 4.7e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 KII88031.1 - 0.017 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KII88031.1 - 0.072 13.3 4.9 0.15 12.3 4.9 1.5 1 0 0 1 1 1 0 B-box zinc finger DUF4218 PF13960.6 KII88032.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) FAM176 PF14851.6 KII88032.1 - 0.12 12.0 0.1 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 FAM176 family ANAPC4_WD40 PF12894.7 KII88033.1 - 7.8e-07 29.3 0.0 0.016 15.5 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Tet_JBP PF12851.7 KII88037.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DivIC PF04977.15 KII88038.1 - 0.21 11.4 0.2 0.32 10.8 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Plavaka PF18759.1 KII88041.1 - 1.7e-132 441.6 0.0 2.3e-132 441.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase LRR_4 PF12799.7 KII88042.1 - 0.2 12.2 0.3 6.4 7.3 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 KII88044.1 - 4.5e-24 84.3 20.4 2.3e-06 28.2 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88044.1 - 3.3e-08 33.7 0.6 0.67 10.3 0.0 5.4 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KII88044.1 - 0.14 11.1 0.0 11 4.8 0.0 2.8 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain FixG_C PF11614.8 KII88044.1 - 0.18 12.0 0.1 1 9.6 0.0 2.0 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Chromo PF00385.24 KII88046.1 - 2.9e-07 30.3 0.1 5.9e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S8 PF00082.22 KII88053.1 - 0.05 12.8 2.6 0.077 12.2 2.0 1.4 1 1 0 1 1 1 0 Subtilase family Pro-kuma_activ PF09286.11 KII88055.1 - 1.6e-30 106.3 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain SAPS PF04499.15 KII88060.1 - 0.014 14.2 7.1 0.018 13.9 7.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KII88060.1 - 0.045 12.0 21.5 0.081 11.1 21.5 1.4 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 KII88060.1 - 0.57 9.7 11.5 1 8.8 11.5 1.5 1 1 0 1 1 1 0 DNA replication and checkpoint protein Zip PF02535.22 KII88060.1 - 2.7 7.1 7.2 1.2 8.2 5.2 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Pro-kuma_activ PF09286.11 KII88063.1 - 5.6e-39 133.7 0.0 6.6e-38 130.2 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII88063.1 - 4.8e-07 29.3 4.1 9.2e-07 28.4 4.1 1.4 1 0 0 1 1 1 1 Subtilase family PMSR PF01625.21 KII88066.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase MFS_1 PF07690.16 KII88067.1 - 2e-40 138.8 69.5 3e-33 115.2 41.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII88067.1 - 0.00012 21.1 8.8 0.00012 21.1 8.8 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KII88067.1 - 0.015 14.2 15.0 0.022 13.7 5.2 3.2 2 1 0 3 3 3 0 MFS_1 like family Ig_mannosidase PF17753.1 KII88068.1 - 6.1e-16 57.9 0.0 2.3e-15 56.1 0.0 2.0 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KII88068.1 - 2.2e-12 47.4 0.2 5.6e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KII88068.1 - 0.0014 19.3 0.1 0.0046 17.6 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MFS_1 PF07690.16 KII88069.1 - 5e-14 52.0 63.4 1.2e-13 50.7 58.1 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_5 PF07994.12 KII88069.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF3450 PF11932.8 KII88070.1 - 0.042 13.1 0.6 0.069 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FmiP_Thoc5 PF09766.9 KII88070.1 - 0.049 12.9 0.2 0.069 12.4 0.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 zf-C3HC4_2 PF13923.6 KII88071.1 - 0.0031 17.3 7.7 0.0031 17.3 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII88071.1 - 0.0051 16.7 7.7 0.0051 16.7 7.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII88071.1 - 0.012 15.9 9.0 0.012 15.9 9.0 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 KII88071.1 - 0.014 15.3 8.8 0.014 15.3 8.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII88071.1 - 0.037 14.1 10.8 0.088 12.8 10.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-NADH-PPase PF09297.11 KII88071.1 - 0.081 12.6 0.3 0.081 12.6 0.3 2.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-RING_11 PF17123.5 KII88071.1 - 0.38 10.5 3.5 0.91 9.3 3.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger Nudix_N_2 PF14803.6 KII88071.1 - 0.82 9.6 6.7 2.4 8.2 0.1 3.8 3 0 0 3 3 3 0 Nudix N-terminal zf-RING_10 PF16685.5 KII88071.1 - 1.9 8.7 9.8 0.26 11.5 5.3 1.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KII88071.1 - 3.3 7.7 17.4 0.13 12.2 8.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 KII88071.1 - 7.8 6.4 10.2 1.4 8.8 5.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KII88072.1 - 1.5e-12 47.5 43.3 1.4e-06 28.4 5.5 4.4 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KII88072.1 - 0.00022 21.2 5.5 0.00022 21.2 5.5 4.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII88072.1 - 0.00029 20.6 2.1 0.00029 20.6 2.1 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KII88072.1 - 0.0012 18.5 1.9 0.0071 16.1 1.9 2.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KII88072.1 - 0.0015 18.8 4.8 0.0015 18.8 4.8 4.8 4 0 0 4 4 4 1 Ring finger domain zf-UDP PF14569.6 KII88072.1 - 1.6 8.9 17.7 0.075 13.2 0.8 3.8 3 1 1 4 4 4 0 Zinc-binding RING-finger Myc_N PF01056.18 KII88073.1 - 0.036 14.0 0.0 0.037 13.9 0.0 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF4551 PF15087.6 KII88073.1 - 0.71 8.6 3.0 0.9 8.3 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DNApol_Exo PF18136.1 KII88075.1 - 1.1e-100 336.4 0.0 2e-100 335.6 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KII88075.1 - 3.6e-47 161.2 0.0 6e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A AA_permease PF00324.21 KII88077.1 - 4.4e-113 378.4 31.5 5e-113 378.2 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII88077.1 - 1e-18 67.4 37.8 1.4e-18 67.0 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KII88078.1 - 3.3e-09 36.5 0.2 3.3e-09 36.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like TolA_bind_tri PF16331.5 KII88078.1 - 0.089 12.9 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation F-box-like PF12937.7 KII88079.1 - 1.4e-11 44.0 0.3 3.6e-11 42.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88079.1 - 0.59 10.1 2.9 0.73 9.8 0.9 2.2 2 0 0 2 2 2 0 F-box domain SQS_PSY PF00494.19 KII88080.1 - 1.8e-10 40.8 0.6 4.1e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Squalene/phytoene synthase SQS_PSY PF00494.19 KII88081.1 - 3.1e-33 115.4 0.0 4.6e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Dus PF01207.17 KII88082.1 - 3.7e-65 220.1 0.0 4.6e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KII88082.1 - 9e-05 22.4 0.0 0.0099 15.7 0.1 2.3 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.15 KII88082.1 - 0.00054 19.5 0.0 0.0016 17.9 0.0 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KII88082.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 KII88082.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 KII88082.1 - 0.14 11.3 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase IMPDH PF00478.25 KII88082.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 KII88082.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Zn_clus PF00172.18 KII88086.1 - 5.4e-05 23.2 11.1 8.9e-05 22.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.21 KII88087.1 - 3.8e-78 262.8 0.1 4.5e-78 262.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family DASH_Dad3 PF08656.10 KII88089.1 - 1.2e-20 73.4 0.0 1.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.32 KII88090.1 - 2.1e-14 53.7 13.5 0.00023 21.9 0.1 7.4 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88090.1 - 2e-10 40.8 0.0 0.0015 18.8 0.0 4.1 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KII88090.1 - 0.0027 16.5 0.3 0.055 12.2 0.2 2.5 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 KII88090.1 - 0.0083 16.0 0.1 0.75 9.6 0.0 2.8 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BTB PF00651.31 KII88091.1 - 0.18 12.0 0.0 8.3 6.7 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.25 KII88092.1 - 2.2e-49 168.2 0.0 2.6e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88092.1 - 5.5e-27 94.7 0.0 7.2e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII88092.1 - 2.9e-05 23.5 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII88092.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII88092.1 - 0.0093 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII88092.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family REPA_OB_2 PF16900.5 KII88093.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein A OB domain Mito_carr PF00153.27 KII88095.1 - 3.5e-56 187.1 3.5 2.9e-22 78.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII88095.1 - 0.0003 20.0 0.0 0.069 12.3 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Formyl_trans_N PF00551.19 KII88096.1 - 6.1e-38 130.4 0.0 9.5e-37 126.5 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase Glyco_hydro_15 PF00723.21 KII88097.1 - 3.6e-49 167.8 0.0 1.8e-48 165.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.25 KII88098.1 - 8.3e-29 100.8 0.2 2.2e-28 99.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88098.1 - 2.1e-18 66.6 0.9 7.6e-18 64.7 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase AAA_13 PF13166.6 KII88098.1 - 0.34 9.5 17.0 0.47 9.0 17.0 1.1 1 0 0 1 1 1 0 AAA domain HNH_2 PF13391.6 KII88100.1 - 0.15 12.2 0.5 0.44 10.7 0.0 2.0 2 1 0 2 2 2 0 HNH endonuclease zf-RING_6 PF14835.6 KII88105.1 - 0.1 12.5 3.5 0.096 12.6 1.1 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ins_P5_2-kin PF06090.12 KII88112.1 - 5.8e-69 233.0 0.0 8.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.7 KII88112.1 - 7.2e-08 32.2 1.3 2.1e-07 30.7 1.3 1.9 1 0 0 1 1 1 1 F-box-like Ins_P5_2-kin PF06090.12 KII88113.1 - 5.4e-72 243.0 0.0 7.3e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.7 KII88113.1 - 1.5e-07 31.2 2.1 5.3e-07 29.4 2.1 2.0 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.21 KII88115.1 - 7e-27 94.5 0.0 9.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Ins_P5_2-kin PF06090.12 KII88117.1 - 3.3e-79 266.7 0.0 5.3e-79 266.1 0.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase F-box-like PF12937.7 KII88117.1 - 7.3e-07 29.0 0.5 1.9e-06 27.6 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88117.1 - 0.0075 16.1 0.4 0.023 14.5 0.4 2.0 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII88118.1 - 1.1e-07 31.6 0.1 5.3e-07 29.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like Tim54 PF11711.8 KII88120.1 - 1.2e-58 198.7 0.0 2.7e-58 197.6 0.0 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.16 KII88121.1 - 2.4e-28 99.0 0.0 3.5e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KII88121.1 - 1.5e-21 77.0 0.0 2.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII88121.1 - 9.2e-10 38.8 0.0 2.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII88121.1 - 4.7e-06 26.9 0.0 2.9e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain YL1 PF05764.13 KII88121.1 - 0.0048 17.0 2.7 0.0048 17.0 2.7 2.9 3 0 0 3 3 3 1 YL1 nuclear protein AAA_22 PF13401.6 KII88121.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII88121.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KII88121.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CKS PF01111.19 KII88122.1 - 1.5e-35 121.3 0.2 1.9e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16_M PF16187.5 KII88123.1 - 2.8e-92 309.0 0.0 5.2e-92 308.1 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KII88123.1 - 1e-39 135.9 0.1 4.4e-39 133.9 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KII88123.1 - 1.3e-19 70.9 0.0 1.1e-08 35.3 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain CwfJ_C_1 PF04677.15 KII88125.1 - 8.8e-29 99.9 0.0 1.5e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KII88125.1 - 7.8e-26 89.5 16.0 7.7e-11 41.6 2.7 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KII88125.1 - 1.5e-12 48.3 0.0 2.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KII88125.1 - 6.4e-09 35.5 9.6 0.0019 18.2 0.2 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 KII88125.1 - 0.17 11.9 4.9 14 5.7 0.2 3.4 2 1 1 3 3 3 0 Zinc knuckle zinc-ribbons_6 PF07191.12 KII88125.1 - 4.4 7.4 9.3 6.4 6.8 2.4 2.9 1 1 1 2 2 2 0 zinc-ribbons NIF PF03031.18 KII88126.1 - 2.1e-19 69.8 0.0 5.1e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 KII88126.1 - 5.6e-06 26.0 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Acid_phosphat_B PF03767.14 KII88126.1 - 0.082 12.5 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) COesterase PF00135.28 KII88127.1 - 2.1e-63 215.0 0.0 2.7e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII88127.1 - 5.8e-13 49.2 0.0 9.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KII88127.1 - 0.059 12.3 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme COesterase PF00135.28 KII88128.1 - 1.1e-90 305.0 0.0 1.7e-90 304.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII88128.1 - 1.2e-05 25.3 0.7 0.00029 20.8 0.2 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold CENP-C_C PF11699.8 KII88129.1 - 1.5e-26 92.4 0.1 2.7e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KII88129.1 - 7.5e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KII88129.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Aha1_N PF09229.11 KII88130.1 - 8.4e-32 110.2 0.0 1.3e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KII88130.1 - 2.7e-16 59.9 0.0 5.6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 KII88130.1 - 0.0032 17.8 1.9 0.0089 16.3 0.2 2.4 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Septin PF00735.18 KII88131.1 - 6.9e-115 383.1 1.4 8.2e-115 382.9 1.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KII88131.1 - 1.9e-08 34.4 0.1 4.6e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KII88131.1 - 7.1e-07 28.8 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KII88131.1 - 3.8e-06 26.6 0.4 0.0002 20.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII88131.1 - 4.1e-06 26.8 0.3 4.1e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KII88131.1 - 5.7e-05 23.2 0.5 0.13 12.3 0.2 2.4 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 KII88131.1 - 0.0006 19.1 0.1 0.0015 17.8 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KII88131.1 - 0.00099 19.6 0.4 0.0017 18.8 0.3 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KII88131.1 - 0.001 18.5 0.3 0.0083 15.5 0.3 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KII88131.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KII88131.1 - 0.003 18.0 0.0 0.005 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KII88131.1 - 0.0044 16.1 0.1 0.0078 15.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 KII88131.1 - 0.0091 15.5 0.3 0.089 12.3 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 KII88131.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KII88131.1 - 0.013 14.5 0.4 0.11 11.6 0.0 2.3 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.6 KII88131.1 - 0.029 14.4 0.3 0.2 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KII88131.1 - 0.035 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 KII88131.1 - 0.036 13.7 0.4 0.24 11.0 0.1 2.3 2 1 0 2 2 2 0 Ras family Roc PF08477.13 KII88131.1 - 0.053 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 KII88131.1 - 0.098 11.8 0.1 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HpcH_HpaI PF03328.14 KII88132.1 - 0.17 11.0 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family GST_N PF02798.20 KII88133.1 - 4.8e-16 58.9 0.0 8.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII88133.1 - 4.2e-13 49.3 0.0 9.5e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII88133.1 - 4.3e-10 39.9 0.0 7.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KII88133.1 - 1.1e-09 38.3 0.0 2.6e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KII88133.1 - 2e-09 37.6 0.0 3.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII88133.1 - 7.7e-07 29.0 0.5 1.7e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4771 PF15995.5 KII88133.1 - 0.18 12.0 0.0 1.2 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) CENP-C_C PF11699.8 KII88134.1 - 1.8e-27 95.4 0.0 2.6e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KII88134.1 - 4.2e-05 23.2 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KII88134.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain EutQ PF06249.12 KII88134.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF4551 PF15087.6 KII88134.1 - 0.23 10.3 0.2 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) COesterase PF00135.28 KII88136.1 - 1.4e-92 311.2 0.0 2e-92 310.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII88136.1 - 8.1e-07 29.1 1.1 1.6e-06 28.2 1.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII88136.1 - 4.1e-05 23.2 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.21 KII88136.1 - 0.086 13.6 1.4 0.35 11.6 1.4 1.9 1 1 0 1 1 1 0 Lectin C-type domain Esterase PF00756.20 KII88136.1 - 0.11 12.1 0.4 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 Putative esterase Aminotran_5 PF00266.19 KII88138.1 - 2.2e-86 290.2 0.0 1e-77 261.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KII88138.1 - 9.8e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KII88138.1 - 0.00046 19.6 0.3 0.0026 17.1 0.3 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KII88138.1 - 0.064 11.8 0.1 0.093 11.2 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_6 PF01341.17 KII88139.1 - 6.8e-105 351.2 3.6 8.4e-105 350.9 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KII88139.1 - 1.2e-12 47.5 10.5 2.9e-12 46.3 10.5 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1681 PF07933.14 KII88140.1 - 3.2e-53 179.4 0.0 3.7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 KII88140.1 - 0.17 10.2 0.0 0.18 10.0 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus CSN8_PSD8_EIF3K PF10075.9 KII88141.1 - 2.7e-10 40.4 0.0 4e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF1800 PF08811.11 KII88141.1 - 0.024 13.6 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Hepar_II_III_N PF16889.5 KII88141.1 - 0.089 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Heparinase II/III N-terminus DUF3835 PF12927.7 KII88142.1 - 0.0051 17.6 0.5 0.12 13.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3835) RRM_1 PF00076.22 KII88143.1 - 6.6e-27 93.1 0.0 1.6e-14 53.5 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KII88143.1 - 0.012 15.6 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KII88143.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 KII88143.1 - 0.094 12.8 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 CAP_GLY PF01302.25 KII88144.1 - 4.4e-20 71.5 0.5 7.1e-20 70.8 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KII88144.1 - 1.7e-08 34.6 1.9 0.19 12.2 0.0 5.6 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KII88144.1 - 3e-07 30.1 0.0 4e-06 26.5 0.0 2.6 1 1 3 4 4 4 1 Leucine-rich repeat LRR_8 PF13855.6 KII88144.1 - 2.8e-05 23.8 2.6 0.48 10.2 0.4 4.9 3 3 1 4 4 4 2 Leucine rich repeat CTV_P6 PF06706.11 KII88144.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein ECH_2 PF16113.5 KII88145.1 - 1.1e-111 373.5 0.0 2.2e-111 372.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KII88145.1 - 6.5e-27 94.4 0.0 5.3e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF2043 PF09740.9 KII88145.1 - 0.18 12.5 0.0 0.35 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2043) IDO PF01231.18 KII88146.1 - 6.2e-123 410.8 0.0 7.6e-123 410.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.10 KII88147.1 - 7e-54 181.6 2.8 1.2e-52 177.5 1.3 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KII88147.1 - 4.1e-34 116.4 1.9 2.6e-33 113.9 0.1 2.6 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KII88147.1 - 1.2e-19 70.2 0.6 2.7e-19 69.1 0.6 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KII88147.1 - 7.1e-14 51.5 0.0 2.8e-12 46.5 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF5521 PF17659.1 KII88147.1 - 0.0027 15.7 0.0 1.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5521) DUF4539 PF15072.6 KII88147.1 - 0.0029 17.6 0.1 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) HSDR_N PF04313.14 KII88147.1 - 0.03 14.3 1.0 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) PLATZ PF04640.14 KII88147.1 - 0.059 14.0 0.5 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 PLATZ transcription factor RuvC_1 PF18516.1 KII88147.1 - 0.11 11.7 0.7 1.9 7.6 0.1 2.3 2 0 0 2 2 2 0 RuvC nuclease domain NUDIX PF00293.28 KII88148.1 - 1.4e-12 47.8 0.0 1.2e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain DUF1989 PF09347.10 KII88150.1 - 2.3e-61 206.3 0.0 2.8e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) COesterase PF00135.28 KII88153.1 - 2e-90 304.1 0.0 2.9e-90 303.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII88153.1 - 6.5e-08 32.7 0.3 1.5e-07 31.5 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII88153.1 - 1.6e-07 31.0 0.1 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family SKIP_SNW PF02731.15 KII88154.1 - 7.7e-73 243.4 0.6 7.7e-73 243.4 0.6 2.2 2 0 0 2 2 2 1 SKIP/SNW domain COesterase PF00135.28 KII88155.1 - 1.3e-91 308.0 0.0 6e-91 305.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII88155.1 - 7.3e-09 35.8 1.5 1.4e-08 34.9 1.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII88155.1 - 2.9e-06 26.9 0.7 6.2e-06 25.8 0.2 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family UL45 PF05473.12 KII88155.1 - 0.5 10.0 2.4 0.28 10.8 0.3 1.6 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like SNF2_N PF00176.23 KII88156.1 - 1.6e-55 188.2 0.0 3.4e-43 147.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KII88156.1 - 2.4e-08 34.3 0.0 5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII88156.1 - 0.0056 16.5 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII88156.1 - 0.018 15.1 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit COMM_domain PF07258.14 KII88156.1 - 0.042 14.0 1.6 0.08 13.1 0.2 2.1 2 0 0 2 2 2 0 COMM domain Pam17 PF08566.10 KII88157.1 - 2.7e-64 216.0 0.0 3.3e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2833 PF11090.8 KII88157.1 - 0.13 12.6 0.1 1.8 9.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2833) SH3_9 PF14604.6 KII88158.1 - 2.5e-08 33.6 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII88158.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Herpes_gE PF02480.16 KII88158.1 - 0.027 13.2 0.8 0.042 12.6 0.8 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Stevor PF17410.2 KII88158.1 - 0.082 12.4 0.3 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2207 PF09972.9 KII88158.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AAA_5 PF07728.14 KII88159.1 - 2.7e-12 46.8 0.0 4.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KII88159.1 - 1.8e-09 37.9 0.0 2.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KII88159.1 - 3.8e-07 30.6 0.0 7.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII88159.1 - 3.4e-05 24.1 0.0 0.00014 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII88159.1 - 0.00012 22.5 0.0 0.0041 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 KII88159.1 - 0.0019 17.2 0.0 0.0086 15.0 0.0 1.7 1 1 0 2 2 2 1 PrkA AAA domain AAA_14 PF13173.6 KII88159.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KII88159.1 - 0.0055 16.2 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KII88159.1 - 0.0062 16.9 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KII88159.1 - 0.0076 16.4 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KII88159.1 - 0.025 14.0 0.0 0.083 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KII88159.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KII88159.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KII88159.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain zf-CCCH PF00642.24 KII88160.1 - 2e-05 24.4 0.6 3.1e-05 23.8 0.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII88160.1 - 0.00025 21.0 2.2 0.00047 20.1 2.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KII88160.1 - 0.0023 17.7 2.8 0.0034 17.1 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KII88160.1 - 0.075 13.7 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Torus domain DUF836 PF05768.14 KII88161.1 - 2.8e-12 46.9 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 KII88161.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain zf-CCHC PF00098.23 KII88161.1 - 0.042 14.0 0.6 0.066 13.3 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_3 PF07859.13 KII88162.1 - 2.2e-10 40.8 0.2 1.2e-09 38.4 0.3 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KII88162.1 - 3.5e-08 32.7 0.0 5.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.28 KII88162.1 - 5e-05 22.4 0.7 0.00031 19.8 0.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KII88162.1 - 0.00035 19.7 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 KII88162.1 - 0.0044 16.3 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII88162.1 - 0.026 15.1 2.2 0.034 14.7 1.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Beta-APP PF03494.13 KII88163.1 - 4.7 7.2 6.0 8.2 6.4 6.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Gly-zipper_Omp PF13488.6 KII88163.1 - 5.2 7.1 13.2 0.11 12.5 5.8 2.0 2 0 0 2 2 2 0 Glycine zipper DUF4616 PF15394.6 KII88163.1 - 7.6 5.4 6.5 9.9 5.0 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) SMN PF06003.12 KII88164.1 - 0.099 11.9 4.9 0.14 11.3 4.9 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Rdx PF10262.9 KII88165.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.6 3 0 0 3 3 3 0 Rdx family Methyltransf_30 PF05430.11 KII88166.1 - 0.023 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Radical_SAM_C PF16199.5 KII88167.1 - 3.6e-30 103.8 0.0 6.8e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KII88167.1 - 1.8e-17 64.2 0.1 7.5e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KII88167.1 - 1.1e-11 45.0 0.2 2.3e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII88167.1 - 1.7e-06 28.0 0.0 5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII88167.1 - 0.0016 18.9 0.1 0.0089 16.4 0.1 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII88167.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein MMM1 PF10296.9 KII88168.1 - 5.4e-12 45.4 0.0 5.1e-08 32.4 0.0 2.7 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 tRNA_Me_trans PF03054.16 KII88169.1 - 3.5e-117 391.2 0.0 4e-117 391.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KII88169.1 - 6.9e-07 28.6 0.0 8.4e-05 21.8 0.1 2.5 2 1 0 2 2 2 2 NAD synthase ATP_bind_3 PF01171.20 KII88169.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ThiI PF02568.14 KII88169.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Mit_ribos_Mrp51 PF11709.8 KII88170.1 - 2.9e-19 69.9 4.8 1.1e-16 61.4 4.8 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit SYF2 PF08231.12 KII88170.1 - 0.093 13.1 0.5 0.2 12.0 0.5 1.5 1 0 0 1 1 1 0 SYF2 splicing factor Nuc_sug_transp PF04142.15 KII88171.1 - 1.5e-93 313.4 11.9 2.8e-93 312.5 11.9 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KII88171.1 - 0.0025 18.0 7.2 0.0025 18.0 7.2 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 KII88171.1 - 0.0026 17.0 11.5 0.007 15.6 11.5 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KII88171.1 - 0.44 9.9 17.5 0.013 14.9 4.8 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family WD40 PF00400.32 KII88172.1 - 0.054 14.4 2.1 10 7.1 0.0 4.1 4 1 0 5 5 5 0 WD domain, G-beta repeat PRKG1_interact PF15898.5 KII88172.1 - 0.11 13.4 1.0 0.3 12.0 1.0 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain GDA1_CD39 PF01150.17 KII88173.1 - 7.2e-102 341.2 0.0 1.4e-93 313.9 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KII88173.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF2630 PF10944.8 KII88174.1 - 0.11 13.0 1.0 0.24 11.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Fungal_trans PF04082.18 KII88176.1 - 8.7e-17 61.0 0.2 1.8e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII88176.1 - 2.3e-05 24.4 7.3 4.3e-05 23.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KII88176.1 - 0.0024 17.9 2.9 0.0024 17.9 2.9 3.5 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 KII88179.1 - 1.6e-42 142.6 29.5 3.2e-06 27.8 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KII88179.1 - 5.4e-14 51.8 1.7 1.2e-13 50.7 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88179.1 - 4e-12 45.7 1.1 8.8e-12 44.6 1.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KII88179.1 - 3.3e-07 29.4 8.1 0.025 13.2 0.1 5.2 5 1 1 6 6 6 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII88179.1 - 6.6e-07 29.5 0.3 6.7 7.1 0.0 5.4 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KII88179.1 - 0.063 12.0 0.0 2 7.0 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like PALB2_WD40 PF16756.5 KII88179.1 - 0.56 9.1 9.4 0.4 9.6 0.9 3.3 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Nop14 PF04147.12 KII88179.1 - 4.5 5.4 4.8 6.2 4.9 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family Hira PF07569.11 KII88179.1 - 8.7 6.0 6.2 30 4.2 0.0 4.1 4 1 1 6 6 6 0 TUP1-like enhancer of split Pro_isomerase PF00160.21 KII88180.1 - 1.6e-53 181.2 0.0 1.8e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tyr_Deacylase PF02580.16 KII88181.1 - 1.8e-51 174.4 0.0 2.2e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PLDc_2 PF13091.6 KII88182.1 - 2e-14 53.6 0.0 3.3e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KII88182.1 - 5e-08 32.8 0.0 0.0091 16.1 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif WD40 PF00400.32 KII88183.1 - 4.9e-31 106.3 37.5 2.7e-05 24.8 0.1 8.7 7 2 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 KII88183.1 - 5e-11 41.9 5.0 0.013 14.2 0.2 5.2 3 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KII88183.1 - 0.0053 15.5 0.1 0.45 9.2 0.0 2.7 2 1 0 2 2 2 2 Nup133 N terminal like AsnC_trans_reg PF01037.21 KII88183.1 - 0.086 12.8 0.0 5.9 6.9 0.0 2.9 2 1 1 3 3 3 0 Lrp/AsnC ligand binding domain PQQ_3 PF13570.6 KII88183.1 - 0.31 11.6 10.7 3.1 8.4 0.1 5.0 7 0 0 7 7 7 0 PQQ-like domain adh_short_C2 PF13561.6 KII88184.1 - 4.9e-37 127.7 0.4 6.1e-37 127.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII88184.1 - 1.1e-24 87.0 0.1 1.3e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII88184.1 - 0.00021 21.3 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KII88184.1 - 0.012 15.6 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.19 KII88184.1 - 0.014 14.1 0.0 0.014 14.1 0.0 1.3 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.21 KII88184.1 - 0.021 14.3 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KII88184.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KII88184.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 KII88184.1 - 0.16 11.3 0.2 0.22 10.9 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KII88185.1 - 2e-36 125.7 5.4 2.3e-36 125.5 5.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII88185.1 - 5.9e-25 87.9 1.6 7.3e-25 87.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.8 KII88185.1 - 0.023 14.5 0.2 0.054 13.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 KII88185.1 - 0.033 14.1 2.3 0.033 14.1 1.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KII88185.1 - 0.033 13.5 0.2 0.056 12.8 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.19 KII88185.1 - 0.062 12.0 0.2 0.12 11.1 0.1 1.4 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase zf-C3HC4_3 PF13920.6 KII88186.1 - 2.7e-09 36.7 16.0 4.3e-09 36.1 16.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII88186.1 - 0.0095 15.8 14.9 0.019 14.8 14.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RVT PF13966.6 KII88186.1 - 0.3 11.8 3.3 12 6.7 2.0 2.8 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase BioY PF02632.14 KII88186.1 - 3 7.9 6.3 0.69 10.0 0.6 2.3 1 1 0 2 2 2 0 BioY family Cyclin_N PF00134.23 KII88189.1 - 3.7e-10 39.6 0.0 5.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KII88189.1 - 9.8e-09 35.8 1.6 2.4e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 Cyclin Virulence_RhuM PF13310.6 KII88189.1 - 0.018 14.3 0.0 0.037 13.2 0.0 1.5 1 1 0 1 1 1 0 Virulence protein RhuM family zf-C4H2 PF10146.9 KII88190.1 - 3.6e-08 34.0 0.4 3.6e-08 34.0 0.4 1.9 2 0 0 2 2 2 1 Zinc finger-containing protein Acetyltransf_1 PF00583.25 KII88191.1 - 2e-08 34.5 0.0 2.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII88191.1 - 1.8e-06 28.3 0.1 4.4e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII88191.1 - 3.7e-05 23.7 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII88191.1 - 0.00029 20.8 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KII88191.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII88191.1 - 0.077 13.1 0.3 0.16 12.1 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain IML1 PF12257.8 KII88192.1 - 5.7e-114 380.0 0.0 8.3e-114 379.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KII88192.1 - 1.8e-16 60.0 0.1 3.6e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_6 PF01341.17 KII88193.1 - 3e-106 355.6 1.1 3.7e-106 355.3 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 F-box-like PF12937.7 KII88197.1 - 4.6e-08 32.8 0.8 1.4e-07 31.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like ADIP PF11559.8 KII88197.1 - 0.035 14.2 4.2 0.054 13.6 4.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pox_A_type_inc PF04508.12 KII88197.1 - 0.079 12.8 0.3 0.27 11.1 0.3 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat SHE3 PF17078.5 KII88197.1 - 0.18 11.5 0.8 0.31 10.7 0.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 KII88197.1 - 0.56 10.3 3.8 1.2 9.3 3.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Fzo_mitofusin PF04799.13 KII88197.1 - 0.81 9.2 4.2 0.2 11.2 1.1 1.5 2 0 0 2 2 2 0 fzo-like conserved region F-box-like PF12937.7 KII88198.1 - 6e-09 35.7 0.1 1.5e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like VRR_NUC PF08774.11 KII88201.1 - 2.1e-25 88.9 0.0 7e-25 87.2 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain SAP PF02037.27 KII88201.1 - 0.0043 16.8 0.4 0.012 15.4 0.1 2.0 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 KII88201.1 - 0.0072 16.2 2.9 0.0095 15.9 0.5 2.3 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain AAA_11 PF13086.6 KII88202.1 - 3.1e-47 161.6 4.0 7.3e-26 91.5 1.1 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KII88202.1 - 2.6e-36 123.7 0.0 4.4e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) UPF1_Zn_bind PF09416.10 KII88202.1 - 3.3e-26 92.1 0.1 2.2e-25 89.4 0.0 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 KII88202.1 - 3.2e-12 46.6 0.1 2.7e-11 43.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KII88202.1 - 6.6e-11 42.7 0.2 2.3e-10 41.0 0.2 1.9 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 KII88202.1 - 1.5e-06 28.3 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KII88202.1 - 4e-05 23.5 0.1 9.8e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KII88202.1 - 0.0001 22.0 0.1 0.0004 20.0 0.1 1.9 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KII88202.1 - 0.00033 20.0 0.0 0.00093 18.5 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.7 KII88202.1 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.6 KII88202.1 - 0.0056 17.0 0.1 0.015 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KII88202.1 - 0.01 15.6 0.5 0.023 14.4 0.4 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 KII88202.1 - 0.033 13.6 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 KII88202.1 - 0.036 14.5 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KII88202.1 - 0.041 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KII88202.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KII88202.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 KII88202.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KII88202.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_12 PF13087.6 KII88203.1 - 2.4e-27 95.8 0.0 4.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RTA1 PF04479.13 KII88204.1 - 4.6e-71 238.7 11.7 4.6e-71 238.7 11.7 1.5 2 0 0 2 2 2 1 RTA1 like protein RTA1 PF04479.13 KII88205.1 - 2.1e-70 236.5 12.1 2.9e-70 236.1 12.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Flu_C_NS1 PF03506.13 KII88205.1 - 0.027 14.5 0.1 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) MtrF PF09472.10 KII88205.1 - 0.11 12.0 1.4 7.9 6.0 0.5 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) YfhO PF09586.10 KII88205.1 - 0.27 9.4 4.7 0.21 9.8 3.4 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO FAD_binding_3 PF01494.19 KII88206.1 - 5.1e-69 233.2 0.0 6.8e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII88206.1 - 0.00076 18.8 0.5 0.02 14.1 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII88206.1 - 0.00093 19.4 0.1 0.0039 17.4 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII88206.1 - 0.0042 16.4 0.1 0.0073 15.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KII88206.1 - 0.0047 15.7 0.1 0.019 13.7 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KII88206.1 - 0.0062 15.7 0.6 0.012 14.7 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KII88206.1 - 0.0068 16.9 0.1 3 8.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII88206.1 - 0.019 14.2 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII88206.1 - 0.04 13.5 3.2 0.046 13.3 0.5 2.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase HERV-K_REC PF15695.5 KII88206.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 FAD_oxidored PF12831.7 KII88206.1 - 0.095 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KII88206.1 - 0.13 11.3 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 KII88206.1 - 0.16 11.5 0.1 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 KII88207.1 - 3.2e-63 214.1 0.0 4.3e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII88207.1 - 0.00022 20.6 0.5 0.027 13.7 0.2 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII88207.1 - 0.00083 19.5 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KII88207.1 - 0.0028 16.4 0.1 0.011 14.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KII88207.1 - 0.0042 16.4 0.2 0.0065 15.8 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII88207.1 - 0.0044 16.2 0.9 0.0074 15.4 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KII88207.1 - 0.0054 17.3 0.1 8.9 7.0 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII88207.1 - 0.01 15.4 1.8 0.059 12.9 1.8 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KII88207.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 KII88207.1 - 0.062 12.8 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 KII88207.1 - 0.1 11.6 0.3 0.15 11.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PhoLip_ATPase_C PF16212.5 KII88208.1 - 1.6e-74 250.9 26.6 1.6e-74 250.9 26.6 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KII88208.1 - 1.4e-22 79.2 0.8 2.8e-22 78.2 0.8 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KII88208.1 - 8.5e-14 52.3 1.7 5.1e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KII88208.1 - 3.5e-10 39.8 0.0 1.7e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KII88208.1 - 7.3e-05 22.6 1.3 0.0045 16.7 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KII88208.1 - 0.088 12.3 0.9 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase HAD PF12710.7 KII88208.1 - 0.091 13.2 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ricin_B_lectin PF00652.22 KII88210.1 - 0.0013 19.0 0.0 0.0018 18.6 0.0 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain F-box-like PF12937.7 KII88212.1 - 0.5 10.3 0.2 0.5 10.3 0.2 2.5 2 0 0 2 2 2 0 F-box-like DUF2378 PF09536.10 KII88213.1 - 0.031 14.2 2.2 38 4.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2378) Tape_meas_lam_C PF09718.10 KII88213.1 - 1.6 8.9 18.6 9.8 6.4 0.4 5.9 5 1 1 6 6 6 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) GPI-anchored PF10342.9 KII88214.1 - 7.1e-06 26.7 0.0 9.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII88214.1 - 0.0033 17.2 0.1 0.004 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 KII88215.1 - 4.3e-05 24.2 0.0 5.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII88215.1 - 0.0034 17.2 0.1 0.0042 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3429 PF11911.8 KII88216.1 - 3.8e-39 134.3 16.5 5.3e-39 133.8 16.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2378 PF09536.10 KII88216.1 - 0.0098 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2378) GPI-anchored PF10342.9 KII88217.1 - 0.00037 21.2 0.0 0.00053 20.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII88217.1 - 0.0033 17.2 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Pkinase PF00069.25 KII88218.1 - 2.3e-08 33.7 0.0 2.6e-07 30.3 0.0 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88218.1 - 5.3e-05 22.6 0.0 9.7e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF948 PF06103.11 KII88219.1 - 0.12 12.6 0.0 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 KII88221.1 - 4.1e-09 36.2 0.0 2.1e-07 30.6 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII88221.1 - 0.00041 19.7 0.0 0.00079 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF948 PF06103.11 KII88222.1 - 0.12 12.7 0.1 26 5.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 KII88223.1 - 3e-07 30.1 0.0 1.1e-05 24.9 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII88223.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.6 KII88224.1 - 2.7e-09 36.7 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII88224.1 - 3.7e-07 29.6 0.0 6.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain EphA2_TM PF14575.6 KII88224.1 - 0.0075 17.1 0.0 0.016 16.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 KII88224.1 - 0.01 15.8 0.6 0.027 14.4 0.6 1.7 1 1 1 2 2 2 0 Rifin Cytomega_TRL10 PF06084.11 KII88224.1 - 0.046 13.7 0.2 0.046 13.7 0.2 1.7 2 0 0 2 2 1 0 Cytomegalovirus TRL10 protein FeoB_associated PF12669.7 KII88224.1 - 0.068 13.6 0.5 0.13 12.7 0.5 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Amnionless PF14828.6 KII88224.1 - 0.076 11.8 1.0 0.1 11.4 1.0 1.2 1 0 0 1 1 1 0 Amnionless hSH3 PF14603.6 KII88224.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF5305 PF17231.2 KII88224.1 - 0.11 11.9 0.8 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) FAM176 PF14851.6 KII88224.1 - 0.16 11.6 1.2 3.6 7.2 0.4 2.3 2 0 0 2 2 2 0 FAM176 family DUF2615 PF11027.8 KII88224.1 - 0.19 11.9 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) PBP1_TM PF14812.6 KII88224.1 - 0.3 11.5 3.9 0.97 9.8 3.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stevor PF17410.2 KII88224.1 - 0.39 10.2 5.6 0.068 12.7 1.8 1.6 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame GREB1 PF15782.5 KII88224.1 - 0.51 7.4 9.3 0.64 7.1 9.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM154 PF15102.6 KII88224.1 - 3.2 7.6 14.7 58 3.6 14.7 2.7 1 1 0 1 1 1 0 TMEM154 protein family SH3_9 PF14604.6 KII88225.1 - 4.4e-10 39.3 0.0 7.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII88225.1 - 6.2e-07 28.9 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII88225.1 - 3.3e-06 26.7 0.1 1.2e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 Variant SH3 domain DUF1180 PF06679.12 KII88225.1 - 0.011 16.2 11.5 0.011 16.2 11.5 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1180) hSH3 PF14603.6 KII88225.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain RIFIN PF02009.16 KII88225.1 - 0.016 15.1 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 KII88225.1 - 0.047 12.5 0.1 0.071 11.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless Vpu PF00558.19 KII88225.1 - 0.14 12.0 1.5 0.33 10.8 0.4 1.9 2 0 0 2 2 2 0 Vpu protein Orf78 PF06024.12 KII88225.1 - 0.22 11.8 0.0 0.45 10.8 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) WD40 PF00400.32 KII88226.1 - 2.6e-24 85.0 15.9 0.00019 22.1 0.1 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KII88226.1 - 4.1e-11 42.6 0.5 9.5e-11 41.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KII88226.1 - 4e-05 23.8 0.0 0.21 11.9 0.0 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KII88226.1 - 0.00011 22.0 0.3 0.00011 22.0 0.3 1.8 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 KII88226.1 - 0.00021 20.7 0.0 0.00075 18.9 0.0 1.9 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 KII88226.1 - 0.00062 18.5 0.1 3.5 6.1 0.0 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 HTH_33 PF13592.6 KII88226.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix PQQ_3 PF13570.6 KII88226.1 - 4.3 8.0 7.4 1.5e+02 3.1 0.1 5.3 4 2 1 5 5 5 0 PQQ-like domain RNA_pol_Rpc34 PF05158.12 KII88227.1 - 2.4e-75 254.0 3.1 2.8e-65 220.9 0.7 2.3 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 KII88227.1 - 0.027 14.6 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HxlR PF01638.17 KII88227.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix SRX PF09201.10 KII88227.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit UPAR_LY6 PF00021.21 KII88228.1 - 0.011 16.5 0.2 0.017 15.8 0.2 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Pkinase PF00069.25 KII88230.1 - 2.7e-09 36.8 0.0 5.8e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88230.1 - 0.00044 19.6 0.0 0.00082 18.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FAA_hydrolase PF01557.18 KII88232.1 - 2.5e-58 197.3 0.0 3.1e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KII88232.1 - 0.00082 19.1 0.5 0.0096 15.7 0.1 2.2 2 0 0 2 2 2 1 KH domain DsrH PF04077.12 KII88232.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 DsrH like protein SAPS PF04499.15 KII88233.1 - 1.9e-130 436.0 0.0 2.9e-130 435.4 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Adap_comp_sub PF00928.21 KII88234.1 - 5e-85 285.1 0.2 6.3e-85 284.7 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KII88234.1 - 2.4e-06 27.5 2.7 4.2e-06 26.8 2.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5618 PF18498.1 KII88234.1 - 0.018 15.3 0.6 0.056 13.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) GPI-anchored PF10342.9 KII88235.1 - 1.2e-09 38.8 0.2 1.6e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HMG_box PF00505.19 KII88236.1 - 7.1e-13 48.8 0.7 2.9e-12 46.8 0.7 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII88236.1 - 7.7e-10 39.2 0.0 2.6e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain Rrn6 PF10214.9 KII88236.1 - 0.22 10.0 9.0 0.29 9.6 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAD_binding_3 PF01494.19 KII88237.1 - 1.8e-51 175.4 0.0 2.6e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII88237.1 - 4.9e-07 29.3 2.0 0.012 14.8 0.5 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII88237.1 - 3.9e-06 26.7 5.4 0.00022 20.9 2.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII88237.1 - 4.8e-06 26.1 0.2 0.00052 19.4 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII88237.1 - 7.5e-06 24.9 0.8 0.024 13.3 0.8 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KII88237.1 - 0.00082 18.6 2.5 0.0016 17.6 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KII88237.1 - 0.004 16.3 4.7 0.19 10.7 1.9 3.0 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KII88237.1 - 0.0052 16.2 2.0 0.0069 15.8 2.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII88237.1 - 0.013 16.0 1.0 6.2 7.5 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII88237.1 - 0.018 15.1 0.6 1 9.3 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KII88237.1 - 0.023 14.9 0.7 0.054 13.7 0.7 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII88237.1 - 0.037 13.3 0.2 0.078 12.2 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KII88237.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KII88237.1 - 0.073 12.4 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KII88237.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KII88237.1 - 0.34 9.9 2.4 0.53 9.3 2.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PAP_assoc PF03828.19 KII88238.1 - 7.3e-18 64.5 0.1 2.1e-17 63.1 0.1 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KII88238.1 - 1.7e-09 37.8 0.0 3.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Methyltransf_25 PF13649.6 KII88239.1 - 5.5e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII88239.1 - 4.8e-11 43.1 0.0 1.9e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KII88239.1 - 1.7e-10 40.8 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KII88239.1 - 5e-09 36.2 0.0 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII88239.1 - 8e-09 35.5 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88239.1 - 5.7e-06 27.0 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII88239.1 - 5.4e-05 22.8 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KII88239.1 - 0.00044 19.3 0.0 0.00069 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KII88239.1 - 0.0013 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KII88239.1 - 0.0022 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KII88239.1 - 0.007 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KII88239.1 - 0.025 15.6 0.0 0.06 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KII88239.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 KII88239.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KII88239.1 - 0.1 12.3 0.1 0.38 10.5 0.1 1.8 2 0 0 2 2 2 0 Lysine methyltransferase CMAS PF02353.20 KII88239.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase F-box-like PF12937.7 KII88240.1 - 1.4e-09 37.7 0.4 2.2e-09 37.0 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88240.1 - 0.0001 22.1 0.1 0.00017 21.4 0.1 1.5 1 1 0 1 1 1 1 F-box domain Nbl1_Borealin_N PF10444.9 KII88241.1 - 4.6e-13 48.6 0.0 7.7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KII88241.1 - 0.014 15.4 20.8 0.53 10.3 8.2 3.3 2 2 0 2 2 2 0 Cell division cycle-associated protein 8 3Beta_HSD PF01073.19 KII88242.1 - 1.3e-64 218.0 0.0 5.5e-59 199.5 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII88242.1 - 1.6e-33 116.2 0.0 6.6e-33 114.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII88242.1 - 7e-19 68.4 0.5 2.2e-14 53.6 0.4 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII88242.1 - 1.1e-13 51.5 0.0 1.6e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KII88242.1 - 1.1e-10 41.1 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KII88242.1 - 1.9e-10 40.3 0.1 3.8e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KII88242.1 - 1e-05 24.9 0.0 4.2e-05 22.8 0.2 2.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KII88242.1 - 0.014 15.0 0.3 0.13 11.8 0.3 2.0 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 KII88242.1 - 0.045 13.7 0.9 0.76 9.7 0.2 2.5 1 1 1 2 2 2 0 KR domain TPP_enzyme_N PF02776.18 KII88244.1 - 1.4e-54 184.3 0.0 6e-54 182.2 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KII88244.1 - 1.4e-48 164.6 0.3 5.4e-47 159.4 0.3 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KII88244.1 - 3.1e-40 137.1 0.7 1e-39 135.4 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain VWA_N2 PF16164.5 KII88245.1 - 0.21 11.8 0.9 4.2 7.6 0.1 2.0 1 1 1 2 2 2 0 VWA N-terminal Hema_esterase PF03996.15 KII88246.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Hemagglutinin esterase DUF481 PF04338.12 KII88247.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF481 TGase_elicitor PF16683.5 KII88247.1 - 0.051 12.3 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase elicitor VP40 PF07447.12 KII88248.1 - 0.15 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 Matrix protein VP40 Plavaka PF18759.1 KII88252.1 - 8.1e-127 422.9 0.0 1.2e-126 422.4 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase F-box-like PF12937.7 KII88259.1 - 0.00036 20.4 0.1 0.0013 18.6 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII88259.1 - 0.014 15.8 0.0 0.91 10.0 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) SRPRB PF09439.10 KII88260.1 - 3.5e-21 75.4 0.0 6e-21 74.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KII88260.1 - 1e-10 41.3 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII88260.1 - 8.9e-09 35.4 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII88260.1 - 1.2e-07 31.3 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 KII88260.1 - 5.9e-05 23.2 0.0 0.39 10.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Roc PF08477.13 KII88260.1 - 0.00018 21.7 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 KII88260.1 - 0.0011 18.3 0.0 0.0015 17.8 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KII88260.1 - 0.0022 17.5 0.0 0.085 12.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 KII88260.1 - 0.0024 18.3 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KII88260.1 - 0.005 16.4 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_25 PF13481.6 KII88260.1 - 0.0083 15.7 0.0 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KII88260.1 - 0.013 15.0 0.0 4.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KII88260.1 - 0.014 14.5 0.0 0.14 11.3 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 KII88260.1 - 0.023 15.1 0.1 0.045 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Parvo_NS1 PF01057.17 KII88260.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ras PF00071.22 KII88260.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Ras family TniB PF05621.11 KII88260.1 - 0.18 11.2 0.0 0.72 9.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein E1_dh PF00676.20 KII88261.1 - 8.4e-113 376.3 0.0 1e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KII88261.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KII88261.1 - 0.0017 18.2 0.6 0.0036 17.1 0.6 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4598 PF15370.6 KII88262.1 - 1.9e-17 63.7 0.4 1.9e-17 63.7 0.4 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) Arm PF00514.23 KII88263.1 - 5.7e-14 51.6 20.2 1.5e-05 24.8 0.1 8.4 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KII88263.1 - 3.8e-11 42.2 30.6 0.00041 20.4 0.2 9.8 11 0 0 11 11 11 3 HEAT repeat Adaptin_N PF01602.20 KII88263.1 - 6.9e-09 34.8 6.0 0.0012 17.5 0.0 5.3 3 1 3 6 6 6 2 Adaptin N terminal region HEAT_2 PF13646.6 KII88263.1 - 9.3e-09 35.6 23.2 0.017 15.5 0.8 7.7 6 3 3 9 9 9 5 HEAT repeats Cnd1 PF12717.7 KII88263.1 - 2.2e-08 34.3 5.5 0.46 10.5 0.2 5.1 2 1 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KII88263.1 - 1.2e-05 25.3 2.2 0.056 13.4 0.0 4.2 3 1 2 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KII88263.1 - 0.00014 22.0 1.8 9.1 6.4 0.0 5.3 4 1 3 7 7 7 1 V-ATPase subunit H HEAT_EZ PF13513.6 KII88263.1 - 0.00097 19.6 0.1 0.00097 19.6 0.1 6.6 7 2 0 7 7 5 2 HEAT-like repeat Arm_2 PF04826.13 KII88263.1 - 0.057 12.9 0.2 0.9 8.9 0.1 2.3 1 1 1 2 2 2 0 Armadillo-like DUF908 PF06012.12 KII88263.1 - 3.2 7.1 6.9 12 5.1 0.3 2.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF908) RTP1_C1 PF10363.9 KII88263.1 - 4.6 7.5 8.4 1.8 8.8 0.3 3.8 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3808 PF10300.9 KII88264.1 - 1.1e-75 255.2 0.0 1.5e-75 254.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KII88264.1 - 5.4e-05 23.6 0.8 0.075 13.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII88264.1 - 0.031 14.4 0.6 24 5.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII88264.1 - 0.11 13.4 3.4 16 6.7 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII88264.1 - 0.22 12.2 4.5 11 6.8 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat CoaE PF01121.20 KII88266.1 - 1e-62 211.0 0.0 1.3e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KII88266.1 - 3e-06 27.8 0.0 1.3e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KII88266.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KII88266.1 - 0.11 12.9 0.1 0.62 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain RAMA PF18755.1 KII88266.1 - 0.13 12.7 0.4 0.45 10.9 0.0 2.1 2 1 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated HSF_DNA-bind PF00447.17 KII88267.1 - 3.7e-32 110.8 1.1 6.4e-32 110.0 1.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KII88267.1 - 0.0074 16.7 0.1 0.018 15.5 0.1 1.6 1 0 0 1 1 1 1 Ets-domain Glyphos_transf PF04464.14 KII88268.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Arrestin_C PF02752.22 KII88269.1 - 2.6e-08 34.4 0.0 7e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KII88269.1 - 0.0036 17.4 0.0 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KII88269.1 - 0.0082 15.9 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Myc-LZ PF02344.15 KII88269.1 - 1.7 8.8 6.5 0.23 11.6 0.5 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain DUF382 PF04037.13 KII88270.1 - 1e-59 200.2 0.7 1e-59 200.2 0.7 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KII88270.1 - 1e-16 60.5 4.5 2.1e-16 59.5 4.5 1.5 1 0 0 1 1 1 1 PSP MitMem_reg PF13012.6 KII88271.1 - 1.3e-35 122.2 1.0 2.1e-35 121.5 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KII88271.1 - 5.2e-30 103.8 0.0 9.3e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-CCHC PF00098.23 KII88272.1 - 1.9e-51 170.0 58.2 3.3e-08 33.2 2.3 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KII88272.1 - 2.3e-12 46.4 46.1 0.009 15.7 1.0 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KII88272.1 - 3.1e-09 36.6 36.8 0.071 13.1 0.5 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.6 KII88272.1 - 0.00016 21.4 52.7 0.16 11.8 1.1 7.4 5 2 2 7 7 7 6 Zinc knuckle TRAF6_Z2 PF18048.1 KII88272.1 - 0.0074 16.4 14.9 0.69 10.1 0.1 5.4 5 1 1 6 6 6 2 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC_5 PF14787.6 KII88272.1 - 0.12 12.1 0.7 0.12 12.1 0.7 6.5 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger COX4 PF02936.14 KII88273.1 - 6.8e-38 129.8 0.0 8.7e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1138 PF06592.13 KII88273.1 - 0.002 18.1 0.1 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1138) Ric8 PF10165.9 KII88273.1 - 0.12 11.3 0.2 0.22 10.5 0.0 1.4 2 0 0 2 2 2 0 Guanine nucleotide exchange factor synembryn DUF1289 PF06945.13 KII88273.1 - 7.1 6.5 5.9 2.8 7.8 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) ATP-synt_Eps PF04627.13 KII88274.1 - 1.2e-19 70.0 2.6 1.8e-19 69.5 2.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 KII88275.1 - 7e-52 175.3 0.0 8.2e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII88275.1 - 1.6e-29 102.5 0.0 2.3e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII88275.1 - 1e-11 44.6 0.0 1.2e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII88275.1 - 6.6e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII88275.1 - 0.0001 21.9 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DSPc PF00782.20 KII88276.1 - 4.3e-26 91.3 0.0 4.8e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KII88276.1 - 0.0024 18.2 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KII88276.1 - 0.0024 17.5 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DEAD PF00270.29 KII88277.1 - 6.2e-45 153.1 0.8 6.2e-45 153.1 0.8 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII88277.1 - 4.4e-32 110.7 0.4 8.3e-31 106.6 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII88277.1 - 6.5e-06 26.2 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII88277.1 - 6.4e-05 23.3 0.2 0.0019 18.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII88277.1 - 0.00052 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KII88277.1 - 0.033 14.2 0.1 0.18 11.7 0.1 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 KII88277.1 - 0.051 12.9 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KII88277.1 - 0.081 13.2 0.7 0.42 10.9 0.2 2.4 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KII88277.1 - 0.093 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MFS_1 PF07690.16 KII88279.1 - 9.9e-28 97.1 76.9 2.9e-20 72.5 39.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbC PF04956.13 KII88279.1 - 0.0053 16.9 2.0 0.0053 16.9 2.0 3.2 3 2 0 3 3 3 1 TrbC/VIRB2 family TMEM251 PF15190.6 KII88279.1 - 0.22 11.4 1.7 0.6 10.1 1.7 1.8 1 0 0 1 1 1 0 Transmembrane protein 251 Fibrillarin PF01269.17 KII88280.1 - 1.6e-101 338.1 0.0 1.8e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KII88280.1 - 6.8e-06 25.9 0.0 9.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KII88280.1 - 0.00063 19.6 0.1 0.0022 17.8 0.0 1.7 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KII88280.1 - 0.034 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KII88280.1 - 0.046 13.8 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KII88280.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PMT PF02366.18 KII88281.1 - 2e-81 273.2 19.3 3.7e-81 272.3 19.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KII88281.1 - 8.2e-61 205.1 10.5 8.2e-61 205.1 10.5 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KII88281.1 - 2e-26 93.0 0.1 3.1e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 MIR domain UCH PF00443.29 KII88282.1 - 1.5e-43 149.1 0.0 2.1e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII88282.1 - 2.6e-07 30.6 0.0 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MIEAP PF16026.5 KII88283.1 - 0.34 11.1 6.4 13 6.0 3.2 2.6 2 0 0 2 2 2 0 Mitochondria-eating protein Prominin PF05478.11 KII88283.1 - 0.53 8.2 4.1 0.52 8.2 0.1 2.3 2 0 0 2 2 2 0 Prominin NPV_P10 PF05531.12 KII88283.1 - 0.76 10.3 9.9 10 6.7 0.0 4.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 KII88283.1 - 1.1 9.5 13.6 16 5.6 1.7 5.2 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 KII88283.1 - 1.8 8.3 12.7 1.6 8.4 0.1 3.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 KII88283.1 - 5.4 7.1 14.6 22 5.1 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KII88283.1 - 8.2 6.6 6.8 20 5.3 0.0 3.9 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 KII88283.1 - 9.6 6.1 19.3 6.5 6.6 0.2 5.5 5 0 0 5 5 5 0 Septum formation initiator zf-C3HC4_3 PF13920.6 KII88284.1 - 4.2e-06 26.5 7.8 4.2e-06 26.5 7.8 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF971 PF06155.12 KII88284.1 - 0.058 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) CTK3 PF12243.8 KII88284.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 ADH_zinc_N PF00107.26 KII88285.1 - 4.6e-20 71.9 0.3 8.9e-20 71.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII88285.1 - 4.1e-11 44.1 0.0 7.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII88285.1 - 0.00011 22.0 0.0 0.0012 18.6 0.0 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KII88285.1 - 0.00022 21.1 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Choline_transpo PF04515.12 KII88286.1 - 4.8e-48 164.0 8.5 4.8e-48 164.0 8.5 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Ribosomal_L37 PF08561.10 KII88287.1 - 6e-17 62.3 10.1 1.5e-14 54.6 0.1 2.6 2 1 0 3 3 3 2 Mitochondrial ribosomal protein L37 CBM_19 PF03427.13 KII88290.1 - 0.014 15.3 0.6 0.014 15.3 0.6 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) Utp21 PF04192.12 KII88291.1 - 4.4e-64 216.2 0.6 7.2e-64 215.5 0.6 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KII88291.1 - 9e-19 67.6 0.0 0.00024 21.4 0.0 7.1 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII88291.1 - 2.6e-15 56.5 13.7 0.0063 17.3 0.0 9.2 9 0 0 9 9 9 3 WD domain, G-beta repeat PQQ_3 PF13570.6 KII88291.1 - 0.0094 16.4 0.5 0.28 11.7 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.11 KII88291.1 - 0.011 14.5 0.2 5.6 5.6 0.1 4.0 3 1 2 5 5 5 0 Nup133 N terminal like Hira PF07569.11 KII88291.1 - 0.014 15.1 0.4 0.53 10.0 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split Nup160 PF11715.8 KII88291.1 - 0.016 13.9 0.2 0.31 9.6 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4477 PF14780.6 KII88291.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) eIF2A PF08662.11 KII88291.1 - 0.11 12.4 0.0 8.1 6.3 0.0 3.4 3 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KII88293.1 - 9.3e-06 26.0 0.3 3.8 8.1 0.0 3.8 3 0 0 3 3 3 3 PQQ-like domain BBS2_Mid PF14783.6 KII88293.1 - 0.0022 18.0 0.2 1.6 8.8 0.0 3.1 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 KII88293.1 - 0.02 15.8 0.1 2.5 9.1 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88293.1 - 0.045 14.1 0.0 11 6.3 0.0 3.5 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII88293.1 - 0.1 11.9 1.7 3.2 7.0 0.1 3.1 4 0 0 4 4 4 0 WD40-like domain Lipase_3 PF01764.25 KII88294.1 - 9.7e-08 32.0 0.0 3.2e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII88294.1 - 0.0011 19.6 0.3 0.0025 18.5 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KII88294.1 - 0.006 16.5 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 KII88294.1 - 0.05 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KII88294.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII88294.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 KII88295.1 - 2.8e-69 234.1 0.0 3.4e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KII88295.1 - 9.4e-13 48.4 0.0 5.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KII88295.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase TauD PF02668.16 KII88296.1 - 3.8e-30 105.6 0.0 5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M20 PF01546.28 KII88297.1 - 1.6e-07 31.3 0.0 3.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KII88297.1 - 2.4e-07 30.6 0.2 4.9e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1905 PF08922.11 KII88297.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Fungal_trans PF04082.18 KII88298.1 - 7.1e-21 74.4 0.0 1.9e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII88298.1 - 3.3e-11 43.1 4.6 7e-11 42.1 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 KII88300.1 - 6.8e-34 116.9 5.5 6.8e-34 116.9 5.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF35_N PF12172.8 KII88300.1 - 0.092 12.7 4.8 0.25 11.3 4.8 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-tcix PF14952.6 KII88300.1 - 0.13 11.9 3.3 0.31 10.7 3.3 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding CTP_transf_like PF01467.26 KII88301.1 - 1.5e-06 28.4 0.1 2.9e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like BTB PF00651.31 KII88301.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Gln-synt_C PF00120.24 KII88302.1 - 3.3e-75 253.3 0.0 9.3e-75 251.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain MARVEL PF01284.23 KII88303.1 - 1.5e-05 25.1 8.0 0.035 14.1 4.6 2.2 2 0 0 2 2 2 2 Membrane-associating domain DUF2721 PF11026.8 KII88303.1 - 0.031 14.1 0.1 7 6.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF3074 PF11274.8 KII88304.1 - 6.7e-44 150.1 0.1 8.7e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Ribosomal_L27 PF01016.19 KII88305.1 - 5.6e-34 116.0 2.3 8e-34 115.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Skp1 PF01466.19 KII88306.1 - 2.9e-29 100.9 0.5 4.7e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KII88306.1 - 1.1e-24 86.4 1.4 1.7e-24 85.8 0.1 2.0 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KII88306.1 - 0.00053 20.2 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.14 KII88306.1 - 0.11 12.5 0.1 0.21 11.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) mRNA_cap_enzyme PF01331.19 KII88307.1 - 1.2e-52 178.6 0.0 1.6e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KII88307.1 - 9.1e-31 106.7 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KII88307.1 - 2.5e-11 43.6 0.0 1.8e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KII88307.1 - 0.0023 18.2 0.0 0.0056 17.0 0.0 1.7 2 0 0 2 2 2 1 RNA ligase Protocadherin PF08374.11 KII88310.1 - 0.043 13.8 0.2 0.063 13.3 0.2 1.2 1 0 0 1 1 1 0 Protocadherin RecC_C PF17946.1 KII88310.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain HSF_DNA-bind PF00447.17 KII88312.1 - 7.6e-32 109.8 2.6 7.6e-32 109.8 2.6 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 KII88312.1 - 1.1e-24 86.7 0.1 3.3e-24 85.2 0.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain OATP PF03137.20 KII88312.1 - 2.7 6.2 5.2 0.31 9.3 0.1 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9_N PF02897.15 KII88314.1 - 0.058 12.2 0.0 0.059 12.2 0.0 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_U4 PF03419.13 KII88315.1 - 0.19 11.0 7.8 0.24 10.7 7.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF5090 PF17009.5 KII88315.1 - 6.3 6.7 7.3 8.9 6.2 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Exo_endo_phos PF03372.23 KII88317.1 - 0.00024 20.7 0.0 0.00028 20.5 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 KII88319.1 - 1e-09 38.3 0.0 6.8e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.20 KII88320.1 - 4.8e-17 61.9 0.0 5.2e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.16 KII88321.1 - 8.7e-19 67.6 32.2 2.1e-14 53.3 20.2 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII88321.1 - 7.3e-06 25.1 1.5 7.3e-06 25.1 1.5 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Phage_connector PF05352.12 KII88321.1 - 0.27 10.6 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 Phage Connector (GP10) Arf PF00025.21 KII88322.1 - 7.8e-68 227.3 0.0 8.7e-68 227.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KII88322.1 - 1.7e-11 43.9 0.0 4.4e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KII88322.1 - 2.5e-10 40.1 0.0 3.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KII88322.1 - 4.6e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KII88322.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KII88322.1 - 3e-06 26.9 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KII88322.1 - 0.00011 21.6 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CENP-M PF11111.8 KII88322.1 - 0.017 14.3 0.0 0.071 12.3 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.9 KII88322.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Coa1 PF08695.10 KII88324.1 - 3e-34 117.2 0.0 4.6e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 LSM14 PF12701.7 KII88325.1 - 7.4e-26 90.1 0.0 1.4e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KII88325.1 - 6.7e-09 36.6 5.0 6.7e-09 36.6 5.0 2.1 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 KII88325.1 - 9.3e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF4407 PF14362.6 KII88326.1 - 4 6.7 11.1 1.3 8.3 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Adenylsucc_synt PF00709.21 KII88327.1 - 9.5e-172 571.6 0.0 1.1e-171 571.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.6 KII88328.1 - 1.8e-30 105.3 0.1 2.2e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Clathrin PF00637.20 KII88329.1 - 1.1e-13 51.3 1.1 4.3e-09 36.4 2.2 3.3 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 KII88329.1 - 1.1e-11 44.8 0.1 1.9e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KII88329.1 - 1.7e-07 31.1 9.2 3e-07 30.3 9.2 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KII88329.1 - 0.0058 16.4 8.4 0.01 15.7 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII88329.1 - 0.14 12.5 9.0 0.25 11.7 9.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KII88329.1 - 0.6 10.1 8.4 1 9.4 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII88329.1 - 4 7.6 7.6 8.3 6.5 7.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KII88329.1 - 9.5 6.6 7.8 18 5.7 7.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain ATP-synt_J PF04911.12 KII88330.1 - 7.5e-25 86.3 0.6 8.4e-25 86.1 0.6 1.0 1 0 0 1 1 1 1 ATP synthase j chain zf-RING_2 PF13639.6 KII88331.1 - 1.6e-06 28.3 8.0 1.6e-06 28.3 8.0 2.1 2 1 0 2 2 1 1 Ring finger domain SWIM PF04434.17 KII88331.1 - 1.8e-06 27.5 0.3 3.8e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 KII88331.1 - 0.0056 16.6 5.4 0.007 16.3 4.1 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 KII88331.1 - 0.0074 16.4 4.7 0.0074 16.4 4.7 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 KII88331.1 - 0.024 14.5 4.8 0.024 14.5 4.8 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KII88331.1 - 0.032 14.1 6.8 0.071 13.0 6.8 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 KII88331.1 - 0.038 14.1 7.1 0.038 14.1 7.1 1.8 2 0 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 KII88331.1 - 0.046 14.0 4.4 0.046 14.0 4.4 2.6 3 0 0 3 3 3 0 RING-like domain zf-RING_UBOX PF13445.6 KII88331.1 - 0.074 13.1 5.4 0.25 11.4 5.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger NOB1_Zn_bind PF08772.11 KII88331.1 - 1.1 9.5 5.7 3.9 7.7 4.2 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ANAPC11 PF12861.7 KII88331.1 - 1.2 9.2 10.7 0.13 12.3 5.3 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KII88331.1 - 2.2 7.9 10.7 0.61 9.7 6.5 2.3 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 KII88331.1 - 7.6 6.5 11.2 0.12 12.3 2.4 2.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prenyltransf PF01255.19 KII88332.1 - 1.6e-75 253.5 0.0 1.9e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Prenyltransf PF01255.19 KII88333.1 - 1.9e-76 256.5 0.0 2.1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.6 KII88333.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) PspC PF04024.12 KII88335.1 - 0.2 11.5 4.6 4.1 7.3 4.0 2.3 2 0 0 2 2 2 0 PspC domain MFS_1 PF07690.16 KII88336.1 - 5.5e-21 74.9 29.4 8.4e-16 57.8 18.6 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Ribosomal_L3 PF00297.22 KII88337.1 - 1.8e-20 73.3 2.9 2.3e-19 69.7 1.7 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Mito_carr PF00153.27 KII88338.1 - 2.1e-43 146.1 0.1 3.5e-14 52.5 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.9 KII88338.1 - 2.1e-16 59.7 7.1 3e-06 26.1 1.1 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor ArsP_1 PF03773.13 KII88338.1 - 0.044 12.9 0.2 0.39 9.8 0.1 2.0 2 0 0 2 2 2 0 Predicted permease DIOX_N PF14226.6 KII88339.1 - 8.2e-25 87.9 0.0 1.3e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII88339.1 - 5.8e-18 65.3 0.0 9.5e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UFD1 PF03152.14 KII88340.1 - 2.3e-70 235.6 0.0 3.1e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Cpn60_TCP1 PF00118.24 KII88341.1 - 2.6e-149 498.0 13.0 3e-149 497.8 13.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSL_N PF06350.12 KII88341.1 - 0.035 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Vps52 PF04129.12 KII88341.1 - 0.043 12.5 0.3 0.074 11.8 0.3 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF3599 PF12206.8 KII88341.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) Fungal_trans PF04082.18 KII88342.1 - 7.9e-31 107.1 0.2 1.1e-30 106.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KII88342.1 - 1.9e-07 31.1 9.6 0.00099 19.4 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII88342.1 - 0.0087 16.8 11.6 0.16 12.9 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KII88342.1 - 0.18 11.7 5.0 0.083 12.8 1.0 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KII88342.1 - 0.39 11.1 1.2 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KII88342.1 - 0.8 9.8 3.1 0.69 10.0 0.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger NMT_C PF02799.15 KII88343.1 - 1.6e-82 276.1 0.0 4.1e-82 274.8 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KII88343.1 - 3.6e-76 254.4 0.0 5.7e-76 253.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KII88343.1 - 1.3e-06 28.5 0.1 6.7e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII88343.1 - 4.8e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII88343.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NTP_transf_9 PF04248.12 KII88343.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Sigma70_ner PF04546.13 KII88343.1 - 1.1 9.1 9.2 2.2 8.1 9.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region ThiF PF00899.21 KII88344.1 - 5.1e-64 215.9 0.0 7e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KII88344.1 - 1.3e-30 105.3 0.1 2.2e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KII88344.1 - 0.0085 16.2 0.2 0.023 14.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KII88344.1 - 0.042 13.4 0.1 0.094 12.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KII88344.1 - 0.074 13.6 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 KII88344.1 - 0.16 12.1 2.8 0.34 11.1 2.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein ApbA PF02558.16 KII88344.1 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 KII88344.1 - 0.17 12.6 0.1 0.41 11.3 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain RTC PF01137.21 KII88345.1 - 1.3e-57 194.6 0.0 1.5e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KII88345.1 - 3.5e-36 123.8 0.0 5.6e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NPR2 PF06218.11 KII88346.1 - 1.1e-93 314.4 6.5 2.1e-78 264.1 5.9 3.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 OGG_N PF07934.12 KII88347.1 - 6.8e-31 106.9 0.0 1.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KII88347.1 - 3.7e-15 56.3 0.0 7.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KII88347.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Torus PF16131.5 KII88348.1 - 2.2e-08 34.7 0.1 3.5e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KII88348.1 - 2.5e-06 27.3 1.9 8.8e-06 25.6 1.9 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KII88348.1 - 0.00013 21.8 2.3 0.00035 20.4 2.3 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII88348.1 - 0.00063 19.5 1.3 0.0018 18.0 1.3 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KII88348.1 - 0.00076 19.7 0.2 0.0022 18.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KII88348.1 - 0.0018 18.6 1.1 0.0047 17.4 1.1 1.7 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 KII88348.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cript PF10235.9 KII88348.1 - 0.96 10.1 5.0 3.5 8.2 0.7 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Sulf_transp PF04143.14 KII88349.1 - 2e-09 37.5 25.1 6.8e-07 29.1 12.9 3.0 1 1 2 3 3 3 3 Sulphur transport DUF726 PF05277.12 KII88350.1 - 6.5e-88 294.9 7.7 8.9e-88 294.5 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_8 PF06259.12 KII88350.1 - 0.008 15.8 0.5 0.02 14.5 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 KII88350.1 - 0.074 12.7 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII88350.1 - 3 8.4 9.4 0.13 12.9 1.5 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family Pkinase_Tyr PF07714.17 KII88351.1 - 1.8e-40 138.8 0.0 2.1e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII88351.1 - 1.8e-33 116.0 0.0 2.2e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KII88351.1 - 0.00015 20.6 0.1 0.00022 20.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII88351.1 - 0.00036 19.9 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII88351.1 - 0.00069 19.0 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII88351.1 - 0.017 15.0 2.1 0.027 14.4 0.3 2.2 1 1 2 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KII88351.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family GMC_oxred_N PF00732.19 KII88352.1 - 1.2e-60 205.4 0.0 1.8e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII88352.1 - 2.1e-34 119.1 0.0 3.8e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KII88352.1 - 1.8e-05 24.0 0.3 0.022 13.8 0.0 3.2 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KII88352.1 - 0.0009 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII88352.1 - 0.0054 16.9 0.1 0.019 15.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII88352.1 - 0.0094 15.6 0.1 0.068 12.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII88352.1 - 0.067 12.4 0.0 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII88352.1 - 0.074 12.3 0.1 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1843 PF08898.10 KII88352.1 - 0.088 13.3 0.3 0.18 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) LEA_2 PF03168.13 KII88353.1 - 8.2e-07 29.5 0.1 1.4e-06 28.8 0.1 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KII88353.1 - 6.1e-05 22.4 0.1 9.2e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Vac7 PF12751.7 KII88353.1 - 0.016 14.6 0.0 0.028 13.9 0.0 1.3 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Cyc-maltodext_N PF09087.11 KII88353.1 - 0.28 11.5 0.4 1.3 9.3 0.4 2.0 1 1 0 1 1 1 0 Cyclomaltodextrinase, N-terminal JmjC PF02373.22 KII88355.1 - 4.9e-13 49.5 0.0 1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase C1_2 PF03107.16 KII88355.1 - 0.019 15.3 0.3 0.019 15.3 0.3 2.2 2 0 0 2 2 2 0 C1 domain zf-C5HC2 PF02928.16 KII88355.1 - 7.3 7.1 12.3 0.25 11.7 0.7 2.9 2 1 0 2 2 2 0 C5HC2 zinc finger Pkinase PF00069.25 KII88356.1 - 8.1e-27 94.2 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88356.1 - 6.1e-13 48.7 0.0 8.8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII88356.1 - 2e-06 26.9 0.0 2.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII88356.1 - 0.014 15.3 0.0 5.7 6.8 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 KII88357.1 - 2.8e-50 170.1 0.0 3.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII88357.1 - 1.7e-30 105.7 0.0 2.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII88357.1 - 3.7e-10 39.5 0.0 4.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII88357.1 - 0.00019 20.9 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII88357.1 - 0.00051 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KII88357.1 - 0.0071 15.6 2.3 1.3 8.1 0.5 2.7 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.22 KII88357.1 - 0.017 15.5 0.1 0.14 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 KII88357.1 - 0.024 14.1 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 KII88357.1 - 0.031 13.8 0.1 0.046 13.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5118 PF17162.4 KII88357.1 - 0.036 13.9 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 KII88357.1 - 0.045 13.5 0.2 0.065 12.9 0.3 1.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII88357.1 - 0.06 13.2 0.0 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KII88357.1 - 0.064 13.6 0.2 0.072 13.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KII88357.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KII88357.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 KII88357.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain Septin PF00735.18 KII88357.1 - 0.15 11.3 0.1 0.24 10.6 0.1 1.4 1 0 0 1 1 1 0 Septin MFS_1 PF07690.16 KII88358.1 - 8.7e-49 166.3 38.4 8.7e-49 166.3 38.4 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII88358.1 - 1.6e-19 69.8 17.0 2.3e-19 69.3 17.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KII88358.1 - 5.2e-12 45.4 10.5 5.2e-12 45.4 10.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Borrelia_P13 PF05628.12 KII88358.1 - 0.011 15.7 0.4 0.08 12.9 0.0 2.4 2 0 0 2 2 2 0 Borrelia membrane protein P13 HlyIII PF03006.20 KII88358.1 - 0.89 9.2 9.1 0.54 9.9 5.4 2.6 1 1 1 2 2 2 0 Haemolysin-III related Vac_ImportDeg PF09783.9 KII88359.1 - 5.2e-54 182.4 0.2 4.2e-53 179.5 0.2 1.9 1 1 0 1 1 1 1 Vacuolar import and degradation protein Pyr_redox_3 PF13738.6 KII88360.1 - 7.9e-13 48.3 0.0 4.6e-11 42.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KII88360.1 - 2.2e-11 42.9 0.1 1.1e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KII88360.1 - 5.7e-10 38.9 0.0 6.7e-08 32.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KII88360.1 - 1.6e-08 34.1 0.0 3.2e-06 26.6 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII88360.1 - 2.3e-08 34.1 0.0 5.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII88360.1 - 8.4e-05 22.3 0.1 0.0019 17.9 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII88360.1 - 0.0046 16.9 0.0 0.072 13.1 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KII88360.1 - 0.078 12.3 0.0 7.8 5.6 0.0 3.1 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KII88360.1 - 0.079 12.0 0.1 26 3.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A He_PIG PF05345.12 KII88362.1 - 0.0047 17.1 0.2 0.052 13.7 0.0 2.7 2 0 0 2 2 2 1 Putative Ig domain LUC7 PF03194.15 KII88365.1 - 5.9e-70 235.8 2.7 7.7e-70 235.4 2.7 1.1 1 0 0 1 1 1 1 LUC7 N_terminus DUF3367 PF11847.8 KII88365.1 - 0.041 11.8 0.1 0.046 11.6 0.1 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase ATP-synt_D PF01813.17 KII88366.1 - 1.7e-71 240.1 2.5 1.7e-71 240.1 2.5 1.3 2 0 0 2 2 2 1 ATP synthase subunit D HtrL_YibB PF09612.10 KII88366.1 - 0.053 13.0 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) PriCT_1 PF08708.11 KII88366.1 - 0.067 12.9 0.2 0.17 11.6 0.1 1.7 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) DUF4795 PF16043.5 KII88366.1 - 0.72 9.4 4.0 1.5 8.3 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Ribosomal_L26 PF16906.5 KII88367.1 - 8.7e-36 122.3 4.1 1.2e-35 121.8 4.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KII88367.1 - 5.8e-09 35.6 4.2 5.8e-09 35.6 4.2 2.1 2 0 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.14 KII88367.1 - 0.17 11.2 0.1 0.21 10.9 0.1 1.1 1 0 0 1 1 1 0 RNA methyltransferase FRG1 PF06229.12 KII88368.1 - 2.8e-25 89.2 0.1 4.7e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KII88368.1 - 0.0033 17.6 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 Fascin domain DUF1754 PF08555.10 KII88368.1 - 0.065 14.0 14.0 0.63 10.9 1.9 2.5 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) UCH PF00443.29 KII88369.1 - 6.2e-35 120.9 0.4 9.3e-35 120.3 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII88369.1 - 5.7e-16 59.0 2.1 3.1e-15 56.6 2.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KII88369.1 - 7.4e-05 22.4 0.1 0.00017 21.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KII88369.1 - 0.025 15.2 0.0 9.4 6.9 0.0 3.0 2 0 0 2 2 2 0 DUSP domain zf-RanBP PF00641.18 KII88369.1 - 0.1 11.9 8.8 0.025 13.9 3.0 3.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Gaa1 PF04114.14 KII88370.1 - 3.4e-109 366.1 0.2 6.4e-108 361.9 0.2 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component TAFII55_N PF04658.13 KII88371.1 - 1.2e-58 197.4 0.8 1.2e-58 197.4 0.8 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region BUD22 PF09073.10 KII88371.1 - 0.0011 18.4 17.6 0.0011 18.4 17.6 2.2 1 1 1 2 2 2 1 BUD22 DUF4032 PF13224.6 KII88371.1 - 0.058 13.3 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) FlxA PF14282.6 KII88371.1 - 0.39 10.7 5.5 0.96 9.5 1.0 2.7 2 0 0 2 2 2 0 FlxA-like protein Ank_2 PF12796.7 KII88372.1 - 1.9e-17 63.6 0.0 1.3e-08 35.3 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) DnaJ PF00226.31 KII88372.1 - 6.8e-16 58.2 0.1 1.7e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Ank_4 PF13637.6 KII88372.1 - 4.8e-09 36.6 0.0 1.7e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII88372.1 - 6.7e-08 32.2 0.0 0.041 14.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KII88372.1 - 1.8e-06 28.1 0.0 0.0093 16.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KII88372.1 - 8.4e-06 26.0 0.0 0.084 13.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Borrelia_P83 PF05262.11 KII88372.1 - 0.94 7.9 12.3 1.3 7.4 12.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 KII88372.1 - 2.7 7.3 7.8 4.8 6.4 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BCS1_N PF08740.11 KII88373.1 - 4.8e-50 170.2 2.1 6.4e-50 169.7 2.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KII88373.1 - 2e-17 63.8 0.0 3.6e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII88373.1 - 0.00015 22.2 0.1 0.0005 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KII88373.1 - 0.0011 18.6 0.0 0.0058 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII88373.1 - 0.0037 17.4 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII88373.1 - 0.0056 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 KII88373.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KII88373.1 - 0.019 15.5 0.0 0.066 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII88373.1 - 0.029 14.8 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KII88373.1 - 0.054 14.0 0.0 0.099 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KII88373.1 - 0.056 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KII88373.1 - 0.068 13.4 0.0 0.31 11.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KII88373.1 - 0.071 12.8 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KII88373.1 - 0.098 13.1 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KII88373.1 - 0.1 12.5 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KII88373.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KII88373.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KII88373.1 - 0.13 12.1 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KII88373.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain WBS_methylT PF12589.8 KII88374.1 - 9.2e-22 77.6 7.4 9.2e-22 77.6 7.4 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KII88374.1 - 4.1e-09 37.0 0.0 8.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII88374.1 - 2.2e-07 31.5 0.0 4.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88374.1 - 6.6e-05 23.6 0.1 0.00031 21.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII88374.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII88374.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 KII88374.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TRAPP PF04051.16 KII88375.1 - 1.6e-34 118.7 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEC-1_N PF04625.13 KII88375.1 - 0.14 11.2 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF111 PF01969.17 KII88375.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Exo_endo_phos PF03372.23 KII88376.1 - 2.2e-13 50.3 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 KII88376.1 - 0.42 10.4 0.0 0.42 10.4 0.0 1.5 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein DUF5123 PF17161.4 KII88379.1 - 3.1 8.9 7.0 27 5.9 4.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF5123) Tom37 PF10568.9 KII88380.1 - 2.3e-30 105.5 0.0 3.6e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 KII88380.1 - 7.4e-11 41.7 0.0 2e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KII88380.1 - 2.9e-10 40.8 0.0 6.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 KII88380.1 - 5.3e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII88380.1 - 0.0019 18.4 0.0 0.036 14.2 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII88380.1 - 0.076 13.2 0.0 0.32 11.2 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain XAP5 PF04921.14 KII88381.1 - 7.1e-87 291.4 5.1 7.1e-87 291.4 5.1 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF2333 PF10095.9 KII88381.1 - 0.13 11.2 3.5 0.2 10.6 3.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Ribosomal_S13 PF00416.22 KII88382.1 - 1.7e-22 80.2 0.0 2.2e-11 44.3 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 KII88382.1 - 5.6e-05 22.1 0.0 9.2e-05 21.4 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 KII88382.1 - 0.011 16.0 0.0 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 IMS family HHH motif DNA_pol_lambd_f PF10391.9 KII88382.1 - 0.15 11.9 0.1 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda OTU PF02338.19 KII88383.1 - 1.5e-06 28.7 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease SecY PF00344.20 KII88383.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 SecY translocase Acyl-CoA_dh_1 PF00441.24 KII88384.1 - 1.1e-29 103.6 0.5 1.9e-29 102.8 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII88384.1 - 4.2e-17 62.1 0.4 8.3e-17 61.2 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KII88384.1 - 1.9e-15 56.8 0.0 5.5e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KII88384.1 - 2.1e-13 50.9 0.0 8e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KII88384.1 - 9.5e-07 29.2 0.2 2.3e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KII88385.1 - 3.7e-30 105.1 0.4 6.4e-30 104.3 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII88385.1 - 7.7e-17 61.3 0.3 1.4e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KII88385.1 - 4.9e-15 55.4 0.0 1.4e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KII88385.1 - 2.8e-14 53.7 0.0 2.5e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KII88385.1 - 8.1e-07 29.4 0.2 1.9e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KII88386.1 - 3.3e-60 204.2 0.0 4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDUF_C2 PF06374.11 KII88386.1 - 0.17 12.0 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) p450 PF00067.22 KII88387.1 - 0.08 11.7 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 UCR_hinge PF02320.16 KII88388.1 - 3.1e-18 65.7 14.4 4.5e-11 42.8 9.1 2.4 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein DUF3391 PF11871.8 KII88388.1 - 0.064 13.8 3.2 0.079 13.5 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Clusterin PF01093.17 KII88388.1 - 0.069 12.2 4.9 0.077 12.0 4.9 1.0 1 0 0 1 1 1 0 Clusterin DUF3408 PF11888.8 KII88388.1 - 0.19 11.8 5.0 0.26 11.4 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EB PF01683.18 KII88388.1 - 0.78 10.1 7.5 4.7 7.6 7.5 2.0 1 1 0 1 1 1 0 EB module p450 PF00067.22 KII88389.1 - 3.4e-54 184.3 0.0 4.5e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 KII88390.1 - 1e-55 188.9 0.0 1.6e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KII88390.1 - 1.3e-45 155.8 6.3 2.5e-45 154.9 6.3 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KII88390.1 - 2.2e-16 60.2 0.0 6.3e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII88390.1 - 5.8e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KII88390.1 - 0.00059 19.1 0.7 0.0025 17.0 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 U1snRNP70_N PF12220.8 KII88390.1 - 1.3 9.7 7.5 0.2 12.3 1.9 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FAM176 PF14851.6 KII88390.1 - 1.5 8.4 4.1 12 5.5 0.5 2.5 2 0 0 2 2 2 0 FAM176 family Pkinase PF00069.25 KII88391.1 - 1.6e-56 191.6 0.0 1.9e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88391.1 - 1e-40 139.7 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII88391.1 - 0.00089 18.7 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PQ-loop PF04193.14 KII88392.1 - 2.1e-37 126.7 7.9 2.4e-18 65.6 2.7 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KII88392.1 - 0.0065 16.5 1.0 0.015 15.3 0.4 1.9 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange GYF PF02213.16 KII88393.1 - 5.4e-06 26.0 1.1 1.2e-05 24.9 1.1 1.6 1 0 0 1 1 1 1 GYF domain Epimerase PF01370.21 KII88394.1 - 3.4e-08 33.3 0.1 2.2e-05 24.1 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII88394.1 - 3.2e-05 23.9 0.2 8.4e-05 22.5 0.0 1.8 3 0 0 3 3 3 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII88394.1 - 0.0026 16.8 0.0 0.099 11.6 0.0 2.7 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KII88394.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KII88394.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADK PF00406.22 KII88395.1 - 1.7e-44 151.6 0.0 2.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KII88395.1 - 5.5e-20 72.2 0.0 1e-19 71.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KII88395.1 - 9.9e-14 51.0 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KII88395.1 - 2.1e-06 28.3 0.1 4.9e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII88395.1 - 1.2e-05 25.5 0.0 0.00024 21.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KII88395.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 KII88395.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Methyltransf_PK PF05891.12 KII88396.1 - 7.6e-53 179.3 0.0 1.8e-32 112.7 0.0 2.3 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KII88396.1 - 6.6e-06 26.7 0.0 0.054 14.2 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 KII88396.1 - 0.0003 21.4 0.1 0.16 12.6 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88396.1 - 0.00052 20.7 0.0 0.012 16.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII88396.1 - 0.00085 19.2 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RPA_C PF08784.11 KII88398.1 - 1.2e-15 58.0 0.4 3.6e-15 56.5 0.2 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KII88398.1 - 2.6e-06 27.3 1.0 4.5e-06 26.6 1.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_27 PF13463.6 KII88398.1 - 0.00044 20.7 0.0 0.0012 19.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KII88398.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 MarR family GntR PF00392.21 KII88398.1 - 0.0079 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family CMD PF02627.20 KII88398.1 - 0.026 14.6 0.1 0.071 13.2 0.1 1.7 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family RMI2 PF16100.5 KII88398.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Fe_dep_repress PF01325.19 KII88398.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KII88398.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 KII88398.1 - 0.1 12.5 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 MarR family NTF2 PF02136.20 KII88398.1 - 0.13 12.8 0.1 2.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Pinin_SDK_N PF04697.13 KII88398.1 - 0.14 12.8 0.4 1.1 9.9 0.0 2.4 3 0 0 3 3 3 0 pinin/SDK conserved region NatB_MDM20 PF09797.9 KII88399.1 - 8.2e-76 255.4 2.5 1.6e-75 254.4 2.5 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 KII88399.1 - 1.8e-07 31.4 0.0 0.0024 18.6 0.0 4.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII88399.1 - 0.00014 22.3 0.0 9.8 6.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KII88399.1 - 0.0016 18.9 0.3 0.0082 16.6 0.0 2.4 2 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 KII88399.1 - 0.0086 15.3 1.7 0.12 11.5 0.1 2.6 2 1 0 3 3 3 1 Tetratricopeptide repeat NCE101 PF11654.8 KII88400.1 - 3.5e-20 71.4 0.2 5.5e-20 70.8 0.2 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 HAD_2 PF13419.6 KII88401.1 - 6.4e-15 55.7 0.0 5.9e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII88401.1 - 5.7e-13 49.6 0.0 1.1e-12 48.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII88401.1 - 0.00073 19.6 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KII88401.1 - 0.035 14.5 0.1 0.2 12.0 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 KII88401.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TyeA PF09059.10 KII88401.1 - 0.11 12.6 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 TyeA PAC3 PF10178.9 KII88402.1 - 0.0072 16.5 1.3 0.024 14.8 1.3 1.9 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 Med16 PF11635.8 KII88403.1 - 1.5e-05 23.2 0.0 0.0036 15.3 0.1 2.1 2 0 0 2 2 2 2 Mediator complex subunit 16 Condensation PF00668.20 KII88404.1 - 0.015 14.0 0.0 0.4 9.3 0.0 2.3 2 0 0 2 2 2 0 Condensation domain SHOCT PF09851.9 KII88404.1 - 0.021 14.6 0.3 0.043 13.6 0.3 1.6 1 0 0 1 1 1 0 Short C-terminal domain PNTB PF02233.16 KII88405.1 - 5.3e-174 579.5 23.2 5.3e-174 579.5 23.2 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KII88405.1 - 8.4e-74 247.5 1.5 3.1e-73 245.6 0.3 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KII88405.1 - 3.4e-44 150.4 0.1 8.8e-44 149.1 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KII88405.1 - 3.3e-31 107.6 3.5 3.3e-31 107.6 3.5 5.0 4 2 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KII88405.1 - 0.0069 15.8 2.7 5.8 6.2 0.0 4.2 3 1 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KII88405.1 - 0.022 14.0 1.6 0.023 13.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 KII88405.1 - 0.064 13.0 0.1 0.3 10.8 0.1 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DHDPS PF00701.22 KII88406.1 - 7.2e-27 93.8 0.0 3.2e-26 91.7 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-AN1 PF01428.16 KII88407.1 - 0.15 12.2 1.3 0.15 12.2 1.3 1.5 2 0 0 2 2 2 0 AN1-like Zinc finger TruB_N PF01509.18 KII88408.1 - 2.4e-45 154.6 0.0 7.4e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KII88408.1 - 0.00041 20.4 0.2 0.0021 18.2 0.1 2.2 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Chromo_2 PF18704.1 KII88408.1 - 0.2 12.0 0.5 0.36 11.1 0.5 1.4 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 Cu_bind_like PF02298.17 KII88409.1 - 1.1e-07 31.7 3.7 0.011 15.7 0.2 3.8 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.20 KII88409.1 - 0.00034 21.0 0.9 1.4 9.4 0.1 3.1 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 KII88409.1 - 0.00095 19.3 0.0 0.091 12.9 0.0 2.7 2 0 0 2 2 2 1 Cupredoxin-like domain MFS_1 PF07690.16 KII88410.1 - 2.2e-25 89.4 36.0 6e-14 51.7 25.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF5392 PF17370.2 KII88410.1 - 0.011 15.8 1.5 4.7 7.3 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5392) PlyB_C PF18684.1 KII88410.1 - 0.047 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Pleurotolysin B C-terminal domain FixQ PF05545.11 KII88410.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Nuc_sug_transp PF04142.15 KII88411.1 - 1.8e-97 326.3 18.6 2.8e-97 325.7 18.6 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 KII88411.1 - 1.1e-05 24.5 7.6 2.9e-05 23.2 3.5 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KII88411.1 - 0.00012 22.3 5.8 0.00012 22.3 5.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KII88411.1 - 0.00032 20.0 17.2 0.00053 19.3 17.2 1.4 1 1 0 1 1 1 1 UAA transporter family DUF5460 PF17544.2 KII88412.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5460) Tudor_3 PF18115.1 KII88413.1 - 8.3e-15 54.4 0.0 1.7e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 KII88413.1 - 3.6e-06 27.2 0.5 7.7e-05 23.0 0.1 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.6 KII88413.1 - 1.7e-05 24.8 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT_2 PF16589.5 KII88413.1 - 2.6e-05 24.6 0.0 0.22 12.0 0.0 3.1 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain 53-BP1_Tudor PF09038.10 KII88413.1 - 0.00016 21.6 0.0 0.00038 20.4 0.0 1.6 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor Rad9_Rad53_bind PF08605.10 KII88413.1 - 0.00022 21.4 0.0 0.0038 17.4 0.0 2.1 1 1 1 2 2 2 1 Fungal Rad9-like Rad53-binding BRCT_3 PF18428.1 KII88413.1 - 0.0017 18.4 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain TUDOR_5 PF18359.1 KII88413.1 - 0.0044 16.7 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 DUF1325 PF07039.11 KII88413.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 SGF29 tudor-like domain PTCB-BRCT PF12738.7 KII88413.1 - 0.025 14.5 0.0 7.5 6.6 0.0 3.2 3 0 0 3 3 3 0 twin BRCT domain Tudor_2 PF18104.1 KII88413.1 - 0.032 13.9 0.1 0.075 12.7 0.1 1.7 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain DUF2367 PF10164.9 KII88414.1 - 2.6e-06 27.8 6.0 2.6e-06 27.8 6.0 1.5 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2367) zf-LITAF-like PF10601.9 KII88414.1 - 0.0039 17.4 1.3 0.0053 17.0 1.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Chromo PF00385.24 KII88415.1 - 1.1e-09 38.0 2.6 1.9e-09 37.3 2.6 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ATP-synt_Z PF16594.5 KII88415.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Snf7 PF03357.21 KII88416.1 - 2.8e-17 62.8 6.8 4.3e-17 62.2 6.8 1.2 1 0 0 1 1 1 1 Snf7 DUF1378 PF07125.11 KII88416.1 - 0.1 12.8 0.0 0.41 10.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Syntaxin-6_N PF09177.11 KII88416.1 - 0.97 10.0 5.2 15 6.2 0.5 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal FeoB_Cyto PF17910.1 KII88416.1 - 1.4 9.5 7.4 20 5.8 4.7 3.2 2 1 1 3 3 3 0 FeoB cytosolic helical domain Aldo_ket_red PF00248.21 KII88417.1 - 2.1e-35 122.3 0.1 3.7e-34 118.3 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Podoplanin PF05808.11 KII88418.1 - 0.0014 18.8 0.6 0.0022 18.1 0.6 1.3 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KII88418.1 - 0.0021 17.4 4.1 0.0021 17.4 4.1 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain GRA6 PF05084.13 KII88418.1 - 0.0054 16.7 0.3 0.011 15.7 0.3 1.5 1 0 0 1 1 1 1 Granule antigen protein (GRA6) PTP_tm PF18861.1 KII88418.1 - 0.012 15.6 0.0 0.038 14.0 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 KII88418.1 - 0.049 14.2 2.6 0.14 12.7 2.6 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage MGC-24 PF05283.11 KII88418.1 - 0.22 11.9 12.0 0.32 11.4 10.8 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Beta-APP PF03494.13 KII88418.1 - 0.27 11.1 3.6 0.46 10.4 3.6 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) TraT PF05818.12 KII88418.1 - 2.7 7.6 4.4 4.6 6.9 4.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_L30_N PF08079.12 KII88419.1 - 1.7e-28 98.6 16.5 1.7e-28 98.6 16.5 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KII88419.1 - 3.9e-18 65.1 1.2 3.9e-18 65.1 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Tipalpha PF16753.5 KII88419.1 - 0.083 12.7 1.7 1.6 8.5 0.0 2.4 1 1 1 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter CLTH PF10607.9 KII88421.1 - 3e-17 62.9 0.0 4.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KII88421.1 - 2e-06 27.5 0.1 5.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 LisH DAO PF01266.24 KII88422.1 - 9e-37 127.5 0.4 1.1e-36 127.2 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII88422.1 - 8.1e-05 22.0 0.0 0.36 10.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII88422.1 - 0.0029 16.7 0.1 0.81 8.7 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KII88422.1 - 0.0083 15.2 0.4 0.24 10.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain F420_oxidored PF03807.17 KII88422.1 - 0.009 16.6 0.1 5.5 7.7 0.1 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 KII88422.1 - 0.056 13.4 0.3 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KII88422.1 - 0.059 13.6 0.6 0.14 12.4 0.6 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ldh_1_N PF00056.23 KII88422.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 KII88422.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KII88422.1 - 0.24 11.3 0.1 0.41 10.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KII88422.1 - 0.3 11.1 0.8 0.83 9.7 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SRP54 PF00448.22 KII88423.1 - 4.9e-73 245.0 0.6 1e-72 243.9 0.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KII88423.1 - 1.3e-30 105.9 0.5 1.3e-30 105.9 0.5 3.6 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 KII88423.1 - 4.8e-18 65.1 6.2 1.1e-17 64.0 6.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KII88423.1 - 5.5e-05 22.8 0.2 0.00018 21.1 0.2 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KII88423.1 - 0.00016 21.8 0.4 0.00031 20.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KII88423.1 - 0.00083 18.4 0.7 0.0034 16.4 0.1 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KII88423.1 - 0.00084 19.8 1.3 0.0029 18.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KII88423.1 - 0.00092 18.5 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 KII88423.1 - 0.0086 15.8 2.7 0.036 13.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 KII88423.1 - 0.011 15.8 0.0 0.037 14.1 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fe-ADH PF00465.19 KII88423.1 - 0.021 13.7 0.0 0.053 12.3 0.0 1.7 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ResIII PF04851.15 KII88423.1 - 0.094 12.7 0.5 3.9 7.5 0.1 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit MipZ PF09140.11 KII88423.1 - 0.1 11.9 0.2 3.1 7.0 0.2 2.3 1 1 0 1 1 1 0 ATPase MipZ AAA_31 PF13614.6 KII88423.1 - 0.11 12.4 0.3 0.85 9.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 KII88423.1 - 0.14 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Repressor_Mnt PF11423.8 KII88423.1 - 1.1 9.1 8.3 1.1 9.1 0.3 3.2 3 0 0 3 3 3 0 Regulatory protein Mnt WD40 PF00400.32 KII88424.1 - 4.5e-13 49.5 18.8 0.013 16.3 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Methyltransf_23 PF13489.6 KII88425.1 - 4.7e-16 59.1 0.0 6.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII88425.1 - 1.7e-13 51.0 0.0 3.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII88425.1 - 1.1e-11 44.8 0.0 9.1e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII88425.1 - 1.5e-10 41.6 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88425.1 - 2.9e-06 27.9 0.0 7.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KII88425.1 - 3.1e-06 26.0 0.0 8e-06 24.7 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 KII88425.1 - 4.6e-06 26.6 0.0 9.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KII88425.1 - 7.4e-05 22.1 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain MTS PF05175.14 KII88425.1 - 0.00019 21.1 0.0 0.00037 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KII88425.1 - 0.00024 20.5 0.0 0.004 16.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KII88425.1 - 0.00049 19.6 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.15 KII88425.1 - 0.0045 16.9 0.0 0.0099 15.8 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KII88425.1 - 0.0098 15.2 0.0 0.089 12.1 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KII88425.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 KII88425.1 - 0.13 11.6 0.0 0.8 9.0 0.0 1.9 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RRM_1 PF00076.22 KII88426.1 - 2.2e-84 277.3 2.4 2.2e-21 75.4 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KII88426.1 - 6e-26 90.4 0.5 2.2e-25 88.6 0.7 1.9 2 0 0 2 2 1 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KII88426.1 - 4.9e-05 23.4 0.3 9.8 6.4 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KII88426.1 - 5.5e-05 23.1 4.7 0.013 15.5 0.7 3.6 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 KII88426.1 - 0.00022 21.0 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KII88426.1 - 0.0011 19.0 0.4 4.9 7.2 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KII88426.1 - 0.0016 18.1 0.9 7 6.4 0.1 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain XS PF03468.14 KII88426.1 - 0.009 16.3 1.2 0.42 10.9 0.6 3.2 4 0 0 4 4 4 1 XS domain DUF4407 PF14362.6 KII88426.1 - 0.0091 15.4 0.4 0.014 14.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) YflT PF11181.8 KII88426.1 - 0.01 16.3 3.3 0.61 10.6 0.8 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT Limkain-b1 PF11608.8 KII88426.1 - 0.018 15.1 1.6 1 9.5 0.2 3.1 3 0 0 3 3 3 0 Limkain b1 Erf4 PF10256.9 KII88426.1 - 0.21 11.7 0.2 16 5.6 0.0 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Nefa_Nip30_N PF10187.9 KII88426.1 - 0.42 11.0 5.6 0.29 11.5 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SCAMP PF04144.13 KII88427.1 - 1.1e-53 182.2 7.8 1.4e-53 181.8 7.8 1.0 1 0 0 1 1 1 1 SCAMP family Ycf9 PF01737.17 KII88427.1 - 0.18 11.7 2.8 11 5.9 0.0 2.8 3 0 0 3 3 3 0 YCF9 DPBB_1 PF03330.18 KII88428.1 - 3.3e-10 40.1 1.3 7.1e-10 39.0 0.2 2.1 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KII88428.1 - 1.4e-05 24.9 0.3 3.1e-05 23.8 0.3 1.7 1 0 0 1 1 1 1 Barwin family Hamartin PF04388.12 KII88428.1 - 0.033 12.9 9.3 0.04 12.6 9.3 1.2 1 0 0 1 1 1 0 Hamartin protein DEC-1_N PF04625.13 KII88428.1 - 0.054 12.5 5.7 0.067 12.2 5.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Plasmodium_Vir PF05795.11 KII88428.1 - 0.58 9.5 4.8 0.81 9.0 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1387 PF07139.11 KII88428.1 - 1.1 8.9 5.2 1.7 8.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SWI-SNF_Ssr4 PF08549.10 KII88428.1 - 1.3 7.6 6.9 1.8 7.1 6.9 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF4551 PF15087.6 KII88428.1 - 3.6 6.3 7.8 4.7 5.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 KII88428.1 - 6.2 5.4 8.1 7.5 5.1 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3948 PF13134.6 KII88430.1 - 0.038 13.7 3.5 0.29 10.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Doppel PF11466.8 KII88430.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.9 3 0 0 3 3 3 0 Prion-like protein Doppel SH2_2 PF14633.6 KII88431.1 - 2.6e-79 265.6 0.3 2.6e-79 265.6 0.3 2.4 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 KII88431.1 - 4.2e-30 104.2 0.0 8.6e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KII88431.1 - 2.2e-28 98.9 1.9 7.7e-17 61.5 0.0 3.1 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 KII88431.1 - 6.2e-27 94.3 0.0 1.5e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KII88431.1 - 1.1e-19 70.8 29.6 1.1e-19 70.8 29.6 6.0 6 1 1 7 7 7 2 Acidic N-terminal SPT6 SH2 PF00017.24 KII88431.1 - 5.6e-07 29.6 0.0 5.5e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 SH2 domain S1 PF00575.23 KII88431.1 - 8.1e-06 26.1 1.5 2.2e-05 24.7 1.5 1.8 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 KII88431.1 - 3e-05 24.8 3.0 0.00022 22.1 3.0 2.5 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 KII88431.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Tex_N PF09371.10 KII88431.1 - 0.046 13.4 3.4 0.089 12.5 0.0 2.9 3 0 0 3 3 3 0 Tex-like protein N-terminal domain Inv-AAD PF18785.1 KII88432.1 - 3.2e-26 91.7 0.0 5.8e-26 90.9 0.0 1.4 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KII88432.1 - 2.5e-13 49.7 0.0 5.1e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII88432.1 - 0.00063 19.5 1.7 0.011 15.5 1.7 2.2 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 KII88432.1 - 0.19 11.6 0.0 3 7.7 0.0 2.1 1 1 1 2 2 2 0 APOBEC-like N-terminal domain Ribosomal_L24e PF01246.20 KII88435.1 - 1.5e-32 111.6 6.1 3e-32 110.6 6.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e HAGH_C PF16123.5 KII88435.1 - 0.055 14.0 0.4 0.092 13.3 0.4 1.5 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Cytochrom_C550 PF14495.6 KII88435.1 - 0.084 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c-550 domain zf-FCS PF06467.14 KII88435.1 - 0.15 12.0 4.3 0.29 11.1 4.3 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATG_C PF09333.11 KII88436.1 - 1.6e-37 127.7 0.1 3.7e-37 126.6 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KII88436.1 - 1.6e-11 44.3 0.0 4.3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 KII88436.1 - 2.7e-07 30.4 0.0 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 KII88436.1 - 0.00035 20.4 0.0 0.00096 19.0 0.0 1.7 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Lipase_GDSL_2 PF13472.6 KII88437.1 - 2.8e-05 24.6 0.4 5.2e-05 23.7 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII88437.1 - 0.0014 18.6 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Swi3 PF07962.12 KII88438.1 - 1.9e-29 101.4 0.1 3e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DPBB_1 PF03330.18 KII88439.1 - 9e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase HTH_17 PF12728.7 KII88440.1 - 0.0071 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 KII88440.1 - 0.19 11.6 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family WD40 PF00400.32 KII88441.1 - 1.4e-05 25.7 13.8 0.01 16.6 0.7 4.7 4 1 1 5 5 5 3 WD domain, G-beta repeat DUF3915 PF13054.6 KII88441.1 - 0.79 9.7 3.7 0.27 11.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Casc1_N PF15927.5 KII88441.1 - 1.4 8.5 11.4 3.5 7.3 11.4 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Herpes_DNAp_acc PF04929.12 KII88441.1 - 3.2 6.6 7.9 5.5 5.9 7.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AA_permease_2 PF13520.6 KII88442.1 - 2e-84 283.9 40.2 2.5e-84 283.6 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII88442.1 - 1.6e-13 50.1 33.8 4.3e-13 48.7 33.8 1.7 1 1 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 KII88443.1 - 0.00016 21.5 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like PRNT PF15174.6 KII88443.1 - 0.089 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Prion-related protein testis-specific adh_short PF00106.25 KII88444.1 - 8.8e-21 74.2 0.0 1.1e-13 51.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII88444.1 - 1.1e-19 71.0 0.0 3e-13 49.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88444.1 - 0.0043 17.0 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KII88444.1 - 0.045 14.0 0.1 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PRIMA1 PF16101.5 KII88445.1 - 2.8 8.0 7.6 5.8 7.0 7.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KII88445.1 - 6.8 6.1 5.1 11 5.3 5.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAP PF02037.27 KII88446.1 - 1.4e-09 37.4 0.1 1.9e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 SAP domain DUF2315 PF10231.9 KII88447.1 - 9.9e-27 93.5 2.2 2.3e-26 92.3 2.2 1.5 1 1 0 1 1 1 1 Apoptogenic protein 1 MaoC_dehydratas PF01575.19 KII88448.1 - 0.014 15.0 0.1 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 MaoC like domain PTAC PF06130.12 KII88448.1 - 0.056 13.6 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphate propanoyltransferase Histone PF00125.24 KII88449.1 - 2.4e-21 76.5 1.7 2.9e-21 76.2 1.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KII88449.1 - 7.3e-05 23.0 1.4 7.6e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KII88449.1 - 0.00021 21.7 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.11 KII88449.1 - 0.05 13.2 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DFF-C PF09033.10 KII88449.1 - 0.098 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain PRCC PF10253.9 KII88450.1 - 5.1e-28 99.3 15.5 5.1e-28 99.3 15.5 3.3 2 2 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Pet100 PF09803.9 KII88450.1 - 2 9.0 3.8 0.71 10.4 0.4 1.9 2 0 0 2 2 2 0 Pet100 baeRF_family12 PF18856.1 KII88451.1 - 0.031 14.9 0.1 13 6.4 0.0 2.6 1 1 2 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 Nitro_FeMo-Co PF02579.17 KII88451.1 - 4.3 7.7 11.5 2.5 8.5 0.2 4.0 2 1 2 4 4 4 0 Dinitrogenase iron-molybdenum cofactor Pkinase PF00069.25 KII88452.1 - 6e-25 88.1 0.0 1.3e-23 83.7 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88452.1 - 1.2e-09 37.9 0.0 5.1e-07 29.3 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KII88452.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII88452.1 - 0.18 11.1 0.0 30 3.8 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Nucleoporin_C PF03177.14 KII88453.1 - 2.3e-76 257.8 5.1 4.7e-76 256.8 2.0 2.5 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KII88453.1 - 1.9e-15 56.6 0.0 2.7e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HalX PF08663.10 KII88453.1 - 0.016 15.5 0.2 0.059 13.7 0.2 2.0 1 0 0 1 1 1 0 HalX domain Methyltransf_11 PF08241.12 KII88454.1 - 3.9e-13 49.9 0.0 8.4e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII88454.1 - 4.8e-11 43.2 0.0 1.5e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88454.1 - 1e-05 26.2 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII88454.1 - 5.9e-05 23.0 0.0 9.9e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KII88454.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DAGK_cat PF00781.24 KII88455.1 - 4.7e-26 90.9 0.1 1.6e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Histone PF00125.24 KII88456.1 - 5.4e-23 81.8 3.8 6.5e-23 81.5 3.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KII88456.1 - 3.4e-05 24.0 0.1 3.4e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KII88456.1 - 0.00051 20.5 0.0 0.0009 19.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.12 KII88456.1 - 0.073 14.1 2.4 0.16 12.9 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Cytochrome-c551 PF10643.9 KII88456.1 - 0.097 12.2 0.6 0.13 11.8 0.6 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF3408 PF11888.8 KII88456.1 - 2.4 8.3 6.3 2.7 8.1 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Pkinase PF00069.25 KII88457.1 - 5.6e-68 229.2 0.0 7.4e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88457.1 - 5.1e-46 157.1 0.0 7.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KII88457.1 - 2.1e-15 56.9 0.0 3.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KII88457.1 - 1e-14 54.7 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KII88457.1 - 2.3e-12 46.8 0.0 4.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KII88457.1 - 0.00074 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 KII88457.1 - 0.0012 17.7 0.1 0.0024 16.7 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII88457.1 - 0.0013 18.1 0.0 0.0064 15.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like SDA1 PF05285.12 KII88457.1 - 0.0097 15.4 11.9 0.016 14.7 11.9 1.2 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 KII88457.1 - 5.9 6.4 16.6 15 5.1 16.6 1.6 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 KII88457.1 - 8 5.8 9.5 13 5.1 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RTC4 PF14474.6 KII88459.1 - 2.7e-25 88.9 0.0 4.6e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Mitochondr_Som1 PF11093.8 KII88462.1 - 0.094 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Alpha-amylase PF00128.24 KII88464.1 - 2.1e-25 90.0 0.9 8.5e-23 81.4 0.9 2.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KII88464.1 - 6.8e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KII88464.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TRM PF02005.16 KII88465.1 - 1e-120 403.4 0.0 1.6e-120 402.8 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KII88465.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 KII88465.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TFIID-18kDa PF02269.16 KII88466.1 - 2.1e-19 69.3 0.0 3.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.22 KII88467.1 - 1.4e-16 60.0 0.1 2.8e-16 59.1 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII88467.1 - 2.8e-07 30.6 0.0 3.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KII88467.1 - 0.00031 20.6 0.1 0.00051 20.0 0.0 1.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KII88467.1 - 0.007 16.3 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KII88468.1 - 9.5e-11 41.6 0.0 3.8e-09 36.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII88468.1 - 0.00039 19.8 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII88468.1 - 0.23 10.8 1.2 0.4 10.0 1.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2040 PF09745.9 KII88469.1 - 3.3e-35 120.7 22.5 3.3e-35 120.7 22.5 3.4 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.21 KII88470.1 - 8.8e-32 110.4 0.1 1.7e-31 109.4 0.1 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KII88470.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AA_permease_2 PF13520.6 KII88471.1 - 1.1e-62 212.2 39.9 1.4e-62 211.9 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII88471.1 - 2.8e-30 105.4 33.2 4e-30 104.8 33.2 1.2 1 0 0 1 1 1 1 Amino acid permease HMA PF00403.26 KII88472.1 - 7.9e-15 55.0 0.6 9.8e-15 54.8 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Ferric_reduct PF01794.19 KII88473.1 - 9.4e-18 64.5 16.3 9.4e-18 64.5 16.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KII88473.1 - 9.7e-15 55.0 0.0 3.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII88473.1 - 9.6e-13 48.2 0.0 6.4e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Presenilin PF01080.17 KII88473.1 - 0.84 8.3 2.7 1.4 7.6 2.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4211 PF13926.6 KII88474.1 - 8.6e-34 116.7 2.2 8.8e-34 116.6 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) C1_1 PF00130.22 KII88475.1 - 3.7e-08 33.1 3.1 3.7e-08 33.1 3.1 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.6 KII88475.1 - 1.7e-05 23.8 0.6 4.8e-05 22.3 0.0 2.0 3 0 0 3 3 3 1 Cation-channel complex subunit UNC-79 C1_2 PF03107.16 KII88475.1 - 0.28 11.5 14.5 2 8.8 4.3 2.6 2 0 0 2 2 2 0 C1 domain PHD PF00628.29 KII88475.1 - 3.7 7.5 21.1 1.8 8.5 6.8 2.5 2 0 0 2 2 2 0 PHD-finger DPM2 PF07297.12 KII88476.1 - 3.2e-30 104.3 0.4 3.8e-30 104.0 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KII88476.1 - 3.8e-06 26.8 0.1 4.3e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 PIG-P TRAPPC9-Trs120 PF08626.11 KII88477.1 - 1.7e-212 708.1 0.0 4.4e-211 703.4 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Bac_rhamnosid_C PF17390.2 KII88477.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Vps55 PF04133.14 KII88478.1 - 9.9e-44 148.1 5.9 1.1e-43 147.9 5.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2933 PF11666.8 KII88478.1 - 6.9 6.8 7.6 16 5.6 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Kinesin PF00225.23 KII88479.1 - 3.8e-108 361.4 0.0 7.5e-108 360.4 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII88479.1 - 2.1e-23 82.9 0.0 6.5e-23 81.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KII88479.1 - 5.4e-06 26.8 0.2 5.4e-06 26.8 0.2 3.8 3 0 0 3 3 3 1 Kinesin-associated microtubule-binding DUF1968 PF09291.10 KII88479.1 - 0.1 12.6 0.6 0.41 10.7 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) MRP-L47 PF06984.13 KII88479.1 - 0.28 11.3 2.7 28 4.9 0.0 3.3 3 1 0 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Med10 PF09748.9 KII88479.1 - 0.53 10.3 3.6 4.2 7.4 2.3 2.9 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DegQ PF08181.11 KII88479.1 - 0.91 9.7 3.1 5.2 7.2 0.6 2.9 2 0 0 2 2 2 0 DegQ (SacQ) family Elf1 PF05129.13 KII88480.1 - 5.4e-30 103.3 1.1 6.6e-30 103.0 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Nup96 PF12110.8 KII88480.1 - 0.01 15.0 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 zf-CHY PF05495.12 KII88480.1 - 0.013 16.0 0.7 0.019 15.4 0.7 1.3 1 0 0 1 1 1 0 CHY zinc finger Kinesin PF00225.23 KII88481.1 - 3.2e-113 378.0 0.5 3.2e-113 378.0 0.5 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KII88481.1 - 5.4e-29 101.0 0.0 2.5e-28 98.9 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KII88481.1 - 2.2e-08 34.0 2.1 2.2e-08 34.0 2.1 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF465) DUF3584 PF12128.8 KII88481.1 - 0.51 7.8 68.4 0.0049 14.5 19.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) PUF PF00806.19 KII88483.1 - 4.9e-65 211.7 7.3 7.6e-10 37.9 0.0 9.1 9 1 1 10 10 10 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KII88483.1 - 0.019 14.8 0.0 1.6 8.6 0.0 3.5 3 1 1 4 4 4 0 Single Cache domain 2 Sec16_C PF12931.7 KII88484.1 - 1.1e-93 314.2 0.0 1.5e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KII88484.1 - 3.6e-29 101.8 0.0 1.7e-28 99.6 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_C PF12931.7 KII88485.1 - 2.8e-13 50.2 0.0 3.7e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 APC_u15 PF16636.5 KII88485.1 - 0.71 10.3 5.0 1 9.9 2.7 2.3 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 OST3_OST6 PF04756.13 KII88486.1 - 1e-94 317.2 0.0 1.1e-94 317.0 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KII88486.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin 7TMR-DISM_7TM PF07695.11 KII88486.1 - 0.73 9.7 10.0 2 8.2 10.0 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4231 PF14015.6 KII88486.1 - 1.5 9.3 5.2 4.7 7.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PI3_PI4_kinase PF00454.27 KII88487.1 - 2e-34 119.5 0.0 3.8e-33 115.4 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KII88487.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RCDG1 PF15725.5 KII88487.1 - 6.3 7.3 10.2 1.4 9.4 4.3 2.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF3552 PF12072.8 KII88490.1 - 0.1 12.0 8.4 0.15 11.4 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1090 PF06476.12 KII88490.1 - 0.59 10.3 3.3 11 6.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) ExsD PF16806.5 KII88492.1 - 0.0029 17.6 3.5 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Antiactivator protein ExsD DUF4259 PF14078.6 KII88492.1 - 0.0062 17.3 3.4 0.59 10.9 0.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4259) Mod_r PF07200.13 KII88492.1 - 0.0066 16.6 3.8 0.0066 16.6 3.8 1.8 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Ead_Ea22 PF13935.6 KII88492.1 - 0.0067 17.1 3.1 0.0067 17.1 3.1 1.6 2 0 0 2 2 1 1 Ead/Ea22-like protein Fez1 PF06818.15 KII88492.1 - 0.012 16.0 6.6 0.017 15.6 6.6 1.3 1 1 0 1 1 1 0 Fez1 PV-1 PF06637.11 KII88492.1 - 0.014 14.3 2.7 0.021 13.7 2.7 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Halogen_Hydrol PF10112.9 KII88492.1 - 0.017 15.2 6.0 0.99 9.4 3.4 2.8 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-C4H2 PF10146.9 KII88492.1 - 0.018 15.4 7.6 0.022 15.1 7.1 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein MHB PF16525.5 KII88492.1 - 0.025 14.8 0.9 1.1 9.6 0.3 2.5 2 0 0 2 2 2 0 Haemophore, haem-binding EDR1 PF14381.6 KII88492.1 - 0.039 13.7 0.5 0.062 13.0 0.5 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF4192 PF13830.6 KII88492.1 - 0.052 13.6 2.4 0.065 13.3 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) FliD_N PF02465.18 KII88492.1 - 0.054 14.2 1.0 0.12 13.0 0.3 1.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Phage_GP20 PF06810.11 KII88492.1 - 0.057 13.2 6.5 0.034 13.9 4.2 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 KII88492.1 - 0.067 13.4 15.3 0.034 14.4 11.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KII88492.1 - 0.082 13.4 18.0 0.11 13.0 8.9 3.4 2 2 1 3 3 3 0 Cell division protein ZapB T7SS_ESX_EspC PF10824.8 KII88492.1 - 0.093 13.2 3.1 0.32 11.5 3.1 1.9 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm EzrA PF06160.12 KII88492.1 - 0.096 10.9 9.3 0.055 11.6 6.8 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_23 PF13476.6 KII88492.1 - 0.13 12.7 2.2 0.17 12.3 2.2 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.12 KII88492.1 - 0.16 12.0 7.3 4.1 7.5 3.4 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 KII88492.1 - 0.18 11.7 4.3 0.11 12.4 2.3 1.7 2 0 0 2 2 2 0 Sec34-like family Spidroin_N PF16763.5 KII88492.1 - 0.18 11.8 1.8 0.48 10.5 1.6 1.9 1 1 1 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF724 PF05266.14 KII88492.1 - 0.19 11.5 8.2 0.37 10.6 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 KII88492.1 - 0.22 12.2 8.5 0.091 13.4 4.8 2.1 2 1 0 2 2 2 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 KII88492.1 - 0.23 11.5 11.5 0.16 12.0 9.8 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KII88492.1 - 0.25 11.6 12.2 0.089 13.0 7.8 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding 5_nucleotid PF05761.14 KII88492.1 - 0.33 9.8 3.3 0.26 10.2 1.9 1.4 2 0 0 2 2 2 0 5' nucleotidase family FUSC PF04632.12 KII88492.1 - 0.33 9.4 6.0 0.44 9.0 6.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KII88492.1 - 0.35 9.9 6.7 1.3 8.1 6.4 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 KII88492.1 - 0.36 10.5 12.1 2.8 7.6 9.5 2.6 2 1 0 2 2 2 0 GrpE Prefoldin PF02996.17 KII88492.1 - 0.38 10.7 8.3 0.45 10.4 2.6 2.9 3 1 0 3 3 3 0 Prefoldin subunit UPF0242 PF06785.11 KII88492.1 - 0.4 10.8 13.0 0.11 12.5 9.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 KII88492.1 - 0.42 11.1 9.4 5.4 7.6 6.3 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 H-kinase_dim PF02895.14 KII88492.1 - 0.53 10.7 5.3 9.2 6.7 3.1 2.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CENP-H PF05837.12 KII88492.1 - 0.61 10.5 12.8 0.086 13.3 7.6 2.1 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 KII88492.1 - 0.75 9.6 9.0 2.7 7.8 4.4 2.8 1 1 1 2 2 2 0 Septum formation initiator RmuC PF02646.16 KII88492.1 - 0.84 8.7 9.9 3.6 6.6 5.4 2.6 2 1 1 3 3 3 0 RmuC family Herpes_UL6 PF01763.16 KII88492.1 - 0.95 7.9 5.7 1.5 7.2 3.6 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like FemAB PF02388.16 KII88492.1 - 0.97 8.2 4.8 1.5 7.7 4.8 1.3 1 0 0 1 1 1 0 FemAB family Sulfatase_C PF14707.6 KII88492.1 - 1 10.1 3.9 12 6.7 1.2 2.5 1 1 2 3 3 2 0 C-terminal region of aryl-sulfatase OmpH PF03938.14 KII88492.1 - 1.2 9.5 11.6 3.4 8.0 11.6 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 KII88492.1 - 1.2 9.9 13.9 3.4 8.4 8.9 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Fib_alpha PF08702.10 KII88492.1 - 1.3 9.2 6.2 5.6 7.1 1.8 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 KII88492.1 - 1.5 9.3 14.8 1.3 9.6 12.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 KII88492.1 - 1.5 9.0 12.0 3.1 8.1 10.1 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HSCB_C PF07743.13 KII88492.1 - 1.6 9.2 12.4 23 5.6 8.1 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Spc7 PF08317.11 KII88492.1 - 1.8 7.4 13.6 0.37 9.6 10.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 KII88492.1 - 1.9 7.0 8.4 0.95 8.0 6.6 1.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Phage_GPO PF05929.11 KII88492.1 - 2 8.0 8.7 0.5 9.9 5.5 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DHR10 PF18595.1 KII88492.1 - 2.2 8.4 16.8 12 6.0 14.3 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain TSC22 PF01166.18 KII88492.1 - 2.3 8.6 9.1 5.6 7.3 0.1 3.4 2 1 1 3 3 3 0 TSC-22/dip/bun family TMPIT PF07851.13 KII88492.1 - 2.4 7.3 5.5 2.4 7.3 3.7 1.5 1 1 1 2 2 2 0 TMPIT-like protein MCU PF04678.13 KII88492.1 - 3.2 7.8 7.7 1.2 9.2 4.5 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF948 PF06103.11 KII88492.1 - 3.7 7.9 5.2 6.4 7.1 1.1 2.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 KII88492.1 - 7.7 6.6 14.1 4.2 7.4 8.5 2.9 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 KII88492.1 - 9.6 5.5 12.9 1.7 8.0 9.4 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 Glyco_transf_15 PF01793.16 KII88493.1 - 8.8e-127 422.8 4.6 1e-126 422.6 4.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DDE_2 PF02914.15 KII88493.1 - 0.11 12.2 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage Mu transposase Glyco_transf_15 PF01793.16 KII88494.1 - 3e-124 414.5 4.3 3.6e-124 414.3 4.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 KII88495.1 - 2.4e-81 273.2 4.9 2.8e-81 273.0 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin PolyA_pol PF01743.20 KII88495.1 - 0.0058 17.1 0.0 0.41 11.1 0.0 2.8 3 0 0 3 3 3 1 Poly A polymerase head domain ABC_tran PF00005.27 KII88496.1 - 1.9e-23 83.5 0.0 2.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII88496.1 - 1.3e-06 28.5 0.1 0.0079 16.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII88496.1 - 6.4e-05 22.5 0.0 0.0082 15.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KII88496.1 - 0.00065 19.7 0.6 0.0017 18.3 0.2 1.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 KII88496.1 - 0.00073 19.5 0.2 0.0013 18.7 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KII88496.1 - 0.0012 18.6 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KII88496.1 - 0.0021 18.4 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 KII88496.1 - 0.0044 15.7 0.0 0.12 10.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KII88496.1 - 0.0059 16.9 0.0 0.0094 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII88496.1 - 0.0073 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KII88496.1 - 0.0098 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KII88496.1 - 0.012 15.8 0.0 0.39 11.0 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KII88496.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII88496.1 - 0.022 15.3 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KII88496.1 - 0.048 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KII88496.1 - 0.05 13.6 0.3 0.14 12.2 0.2 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 KII88496.1 - 0.051 12.4 0.7 1.9 7.2 0.2 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 KII88496.1 - 0.062 13.5 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 KII88496.1 - 0.092 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family CbiA PF01656.23 KII88496.1 - 0.1 12.7 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pox_A32 PF04665.12 KII88496.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein CPT PF07931.12 KII88496.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein cobW PF02492.19 KII88496.1 - 0.12 12.0 0.2 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.9 KII88496.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 KII88496.1 - 0.19 10.8 0.1 0.33 10.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 KII88496.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Dynactin_p62 PF05502.13 KII88497.1 - 5.4 5.7 7.6 0.24 10.1 0.5 1.9 2 0 0 2 2 2 0 Dynactin p62 family tRNA-synt_2d PF01409.20 KII88498.1 - 7.1e-50 169.8 0.6 6.7e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KII88498.1 - 7.2e-20 71.2 0.4 1.4e-19 70.3 0.1 1.7 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 KII88499.1 - 3.4e-41 140.7 0.1 7.1e-41 139.6 0.1 1.5 1 1 0 1 1 1 1 GrpE FTHFS PF01268.19 KII88500.1 - 1.4e-255 848.7 0.1 2.3e-255 848.1 0.0 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KII88500.1 - 4.3e-67 224.4 0.2 1.1e-66 223.1 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KII88500.1 - 7e-38 129.5 0.6 1.4e-37 128.5 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KII88500.1 - 0.011 14.7 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 KII88500.1 - 0.14 12.2 1.3 4.2 7.4 0.4 3.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PNGaseA PF12222.8 KII88501.1 - 1.7e-137 458.8 5.4 2.3e-137 458.4 5.4 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Pmp3 PF01679.17 KII88502.1 - 5.9e-17 61.6 3.0 8e-17 61.2 3.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 KII88502.1 - 0.013 15.5 0.1 0.022 14.8 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal NapE PF06796.11 KII88502.1 - 0.14 11.7 0.0 0.43 10.1 0.0 1.9 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE BT1 PF03092.16 KII88502.1 - 2.4 6.3 2.8 3.3 5.8 2.8 1.1 1 0 0 1 1 1 0 BT1 family zf-C2H2 PF00096.26 KII88503.1 - 5.4e-20 70.7 30.8 1.3e-05 25.4 0.9 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII88503.1 - 1.1e-17 63.5 26.0 4.8e-07 29.9 0.1 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII88503.1 - 2.5e-10 40.3 25.7 0.027 15.3 0.3 4.8 5 0 0 5 5 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KII88503.1 - 0.0036 17.0 14.0 0.03 14.1 0.3 4.6 4 0 0 4 4 4 1 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KII88503.1 - 0.0051 17.4 7.3 2.1 9.0 0.1 4.0 2 2 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KII88503.1 - 0.022 15.1 8.9 1.6 9.0 2.0 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KII88503.1 - 0.038 14.3 5.3 3.1 8.2 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII88503.1 - 0.56 10.7 9.0 3.8 8.0 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KII88503.1 - 1.9 8.6 0.0 1.9 8.6 0.0 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Ogr_Delta PF04606.12 KII88503.1 - 2.2 8.3 5.0 16 5.5 0.2 3.1 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 KII88503.1 - 3.1 7.6 6.8 1.8 8.4 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-TRAF PF02176.18 KII88503.1 - 4.6 8.0 10.1 3.2 8.5 2.6 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger FBPase PF00316.20 KII88504.1 - 4.3e-75 251.4 0.3 5.4e-75 251.0 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KII88504.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Amidase PF01425.21 KII88505.1 - 3e-95 319.8 0.1 3.8e-95 319.5 0.1 1.0 1 0 0 1 1 1 1 Amidase DUF2418 PF10332.9 KII88506.1 - 1.4e-31 108.9 0.1 2.5e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Kelch_6 PF13964.6 KII88507.1 - 1.1e-11 44.5 15.9 0.3 11.5 0.2 7.2 4 1 2 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KII88507.1 - 2e-10 40.7 10.7 1.2 9.5 0.0 7.5 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KII88507.1 - 4e-08 33.1 8.6 0.001 19.0 0.0 5.9 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KII88507.1 - 9.9e-07 28.5 5.0 0.65 10.1 0.1 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KII88507.1 - 2.4e-06 27.4 18.2 0.23 11.5 0.0 6.1 6 1 1 7 7 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KII88507.1 - 9e-05 22.0 19.5 0.16 11.6 0.0 6.9 7 1 0 7 7 7 4 Kelch motif zf-MYND PF01753.18 KII88507.1 - 0.0008 19.5 7.3 0.0008 19.5 7.3 2.4 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KII88507.1 - 0.0026 18.0 6.0 0.0069 16.7 6.0 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TPR_12 PF13424.6 KII88507.1 - 0.0098 16.2 0.2 0.44 10.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII88507.1 - 0.057 13.1 2.4 2.5 7.8 0.3 2.5 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 KII88507.1 - 0.063 13.4 6.1 0.43 10.8 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII88507.1 - 0.32 11.1 1.7 7.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KII88507.1 - 1.3 9.0 3.3 3.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_4 PF13418.6 KII88508.1 - 8.7e-16 57.7 13.4 0.00041 20.3 0.0 6.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KII88508.1 - 1.3e-15 57.1 11.0 2.7e-06 27.5 0.1 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 KII88508.1 - 2.1e-14 53.1 1.6 0.0023 17.8 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 KII88508.1 - 2.6e-14 53.1 7.2 0.085 13.2 0.0 6.9 6 2 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 KII88508.1 - 4.8e-12 45.3 17.2 6.1e-05 22.5 0.1 7.4 7 1 0 7 7 7 3 Kelch motif TPR_12 PF13424.6 KII88508.1 - 1.8e-05 24.9 0.5 0.73 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Kelch_2 PF07646.15 KII88508.1 - 0.00069 19.5 12.6 0.1 12.6 0.2 6.2 6 1 0 6 6 6 1 Kelch motif zf-MYND PF01753.18 KII88508.1 - 0.0008 19.5 8.3 0.002 18.2 8.3 1.7 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.6 KII88508.1 - 0.00089 18.9 3.7 0.0042 16.7 2.7 2.4 3 0 0 3 3 3 1 TPR repeat zf-C6H2 PF15801.5 KII88508.1 - 0.0013 18.9 9.6 0.0032 17.7 9.6 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TPR_2 PF07719.17 KII88508.1 - 0.0028 17.6 5.9 0.23 11.7 3.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat YHS PF04945.13 KII88508.1 - 0.032 14.3 2.6 15 5.8 0.6 3.6 2 1 1 3 3 3 0 YHS domain TPR_14 PF13428.6 KII88508.1 - 0.067 14.0 0.4 0.96 10.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KII88508.1 - 0.077 12.8 2.9 5.4 7.0 1.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII88508.1 - 0.088 12.9 0.7 0.79 9.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII88508.1 - 0.58 10.9 4.3 0.39 11.4 0.4 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-MYND PF01753.18 KII88509.1 - 2.6e-09 37.0 13.0 2.6e-09 37.0 13.0 4.3 3 1 0 3 3 3 2 MYND finger FYVE_2 PF02318.16 KII88509.1 - 0.0048 17.1 10.4 0.0048 17.1 10.4 2.7 2 1 1 3 3 3 1 FYVE-type zinc finger UPF0086 PF01868.16 KII88510.1 - 4.4e-30 103.4 0.0 7.2e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SpoIIE PF07228.12 KII88511.1 - 4.3e-13 49.6 0.0 6.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KII88511.1 - 0.00076 19.2 0.0 0.0021 17.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KII88511.1 - 0.073 12.7 0.0 5.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C Peptidase_M49 PF03571.15 KII88512.1 - 4.9e-219 728.3 0.0 6.1e-219 728.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Cellulase PF00150.18 KII88513.1 - 1.4e-13 50.9 5.9 6.3e-13 48.8 5.9 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KII88513.1 - 0.00081 19.1 0.1 1.2 8.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KII88513.1 - 0.016 14.4 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KII88513.1 - 0.035 13.5 1.0 0.21 10.9 0.6 2.4 2 1 0 2 2 2 0 Beta-galactosidase TPR_1 PF00515.28 KII88514.1 - 0.0043 16.8 0.2 0.68 9.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII88514.1 - 0.0055 16.7 1.5 10 6.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII88514.1 - 0.0061 16.8 4.0 3 8.2 0.2 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII88514.1 - 0.011 15.6 0.1 7.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII88514.1 - 0.012 15.3 0.5 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 TPR repeat PG_binding_3 PF09374.10 KII88514.1 - 0.071 13.4 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Predicted Peptidoglycan domain TPR_8 PF13181.6 KII88514.1 - 0.1 12.9 2.6 28 5.3 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 KII88514.1 - 0.23 11.2 0.0 0.66 9.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DEAD_2 PF06733.15 KII88515.1 - 3.4e-53 179.9 0.4 2.4e-52 177.1 0.0 2.4 3 0 0 3 3 3 1 DEAD_2 HBB PF06777.11 KII88515.1 - 9.7e-47 159.1 0.9 8.8e-40 136.4 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KII88515.1 - 9.7e-41 139.8 0.0 1.9e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KII88515.1 - 0.00032 20.7 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_M41 PF01434.18 KII88517.1 - 2.8e-55 187.1 4.4 9e-55 185.5 4.4 1.8 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KII88517.1 - 1.9e-43 148.1 0.0 6.5e-43 146.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII88517.1 - 1.8e-08 34.0 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 KII88517.1 - 0.00021 20.6 1.0 0.00034 19.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 KII88517.1 - 0.00024 21.6 0.6 0.011 16.2 0.5 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KII88517.1 - 0.00031 20.8 0.8 0.0022 18.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII88517.1 - 0.00035 20.8 0.1 0.06 13.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KII88517.1 - 0.0005 19.8 0.0 0.0021 17.8 0.0 2.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KII88517.1 - 0.00082 19.9 0.1 0.094 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KII88517.1 - 0.0075 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KII88517.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KII88517.1 - 0.011 15.8 0.3 0.047 13.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KII88517.1 - 0.014 14.8 0.4 0.032 13.6 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KII88517.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KII88517.1 - 0.019 14.2 0.1 0.041 13.1 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KII88517.1 - 0.02 14.3 2.9 0.19 11.0 0.1 2.5 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.6 KII88517.1 - 0.036 14.3 1.0 0.056 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KII88517.1 - 0.041 13.9 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KII88517.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KII88517.1 - 0.086 12.7 0.3 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 KII88517.1 - 0.13 11.9 0.3 0.97 9.1 0.3 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KII88517.1 - 0.17 11.5 0.8 0.98 9.0 0.5 2.3 1 1 1 2 2 2 0 AAA domain GCIP PF13324.6 KII88518.1 - 3.7e-47 161.1 0.4 5.4e-47 160.6 0.4 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting HTH_27 PF13463.6 KII88518.1 - 0.061 13.8 0.0 0.68 10.5 0.1 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain F-box-like PF12937.7 KII88519.1 - 4.9e-06 26.3 0.1 9.6e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88519.1 - 7.9e-05 22.4 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain Glycos_transf_2 PF00535.26 KII88520.1 - 5.6e-34 117.4 0.0 7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KII88520.1 - 4.1e-13 49.8 0.0 5.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KII88520.1 - 4.6e-06 26.3 0.0 5.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-MYND PF01753.18 KII88521.1 - 1.3e-06 28.4 10.7 1.3e-06 28.4 10.7 4.8 3 1 0 3 3 3 2 MYND finger Oxidored_FMN PF00724.20 KII88522.1 - 1e-69 235.4 0.0 1.2e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glucan_synthase PF02364.15 KII88524.1 - 0 1316.7 0.0 0 1316.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KII88524.1 - 1.1e-41 142.2 0.3 3.2e-41 140.7 0.3 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 F-box-like PF12937.7 KII88525.1 - 3.8e-08 33.1 0.1 6.4e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like Snapin_Pallidin PF14712.6 KII88525.1 - 0.03 14.7 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Osmo_CC PF08946.10 KII88525.1 - 0.035 14.3 2.9 0.068 13.4 2.9 1.6 1 1 0 1 1 1 0 Osmosensory transporter coiled coil F-box PF00646.33 KII88525.1 - 0.48 10.4 2.7 0.58 10.1 1.1 2.1 2 1 0 2 2 2 0 F-box domain CRIC_ras_sig PF10534.9 KII88527.1 - 0.16 12.2 1.2 24 5.2 0.6 2.8 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras DUF2390 PF09523.10 KII88527.1 - 0.73 10.2 4.7 2.1 8.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) DMPK_coil PF08826.10 KII88527.1 - 5.9 7.1 17.9 0.069 13.3 1.2 4.3 5 0 0 5 5 5 0 DMPK coiled coil domain like Atg14 PF10186.9 KII88528.1 - 0.00017 20.8 2.0 0.00017 20.8 2.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 KII88528.1 - 0.0014 18.8 6.4 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KII88528.1 - 0.002 18.6 7.8 0.022 15.3 3.8 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region SIKE PF05769.11 KII88528.1 - 0.0066 16.4 1.6 0.0073 16.3 0.4 1.7 2 0 0 2 2 2 1 SIKE family SlyX PF04102.12 KII88528.1 - 0.011 16.4 6.2 0.079 13.6 0.7 3.7 4 0 0 4 4 3 0 SlyX DUF4795 PF16043.5 KII88528.1 - 0.021 14.5 2.2 1.4 8.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) OmpH PF03938.14 KII88528.1 - 0.025 14.9 7.9 0.031 14.6 2.2 2.6 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) DUF4618 PF15397.6 KII88528.1 - 0.069 12.6 5.8 0.41 10.0 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HAUS-augmin3 PF14932.6 KII88528.1 - 0.1 12.2 4.5 4.3 6.8 2.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 GTP-bdg_M PF16360.5 KII88528.1 - 0.13 12.9 6.2 0.51 11.0 0.9 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Cnn_1N PF07989.11 KII88528.1 - 0.3 11.3 10.8 3.9 7.7 3.1 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 PMC2NT PF08066.12 KII88528.1 - 0.86 10.3 3.5 73 4.1 1.1 4.0 3 1 0 3 3 3 0 PMC2NT (NUC016) domain Ax_dynein_light PF10211.9 KII88528.1 - 1.1 9.2 7.3 7.8 6.4 4.0 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 KII88528.1 - 2.3 8.2 13.9 0.89 9.5 5.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.11 KII88528.1 - 2.3 8.8 10.2 2.7 8.6 0.5 3.0 3 0 0 3 3 2 0 Syntaxin 6, N-terminal LXG PF04740.12 KII88528.1 - 2.4 7.8 7.3 0.25 11.0 2.5 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily ZapB PF06005.12 KII88528.1 - 3.8 8.0 18.4 2.8 8.5 8.9 3.6 4 0 0 4 4 3 0 Cell division protein ZapB Spc24 PF08286.11 KII88528.1 - 4.6 7.5 8.1 99 3.3 0.1 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 KII88528.1 - 5.3 7.1 17.4 11 6.1 1.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1043 PF06295.12 KII88528.1 - 6.7 6.7 6.7 7.1 6.7 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Swi5 PF07061.11 KII88528.1 - 7.3 6.8 7.4 33 4.7 0.1 2.5 2 0 0 2 2 2 0 Swi5 FlaC_arch PF05377.11 KII88528.1 - 8.4 6.9 6.4 12 6.4 1.9 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RAI16-like PF10257.9 KII88529.1 - 1.5e-70 237.9 0.0 2.4e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein F-box-like PF12937.7 KII88530.1 - 1.3e-06 28.2 0.4 2e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 F-box-like CLASP_N PF12348.8 KII88531.1 - 3.8e-21 75.7 0.0 4.6e-10 39.4 0.0 4.5 4 0 0 4 4 4 3 CLASP N terminal HEAT_2 PF13646.6 KII88531.1 - 4.3e-08 33.4 16.7 0.11 12.9 0.0 8.5 7 2 2 9 9 9 4 HEAT repeats HEAT PF02985.22 KII88531.1 - 1.2e-07 31.4 16.4 0.23 11.8 0.0 10.3 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 KII88531.1 - 2.7e-07 30.8 0.0 1.8 8.6 0.0 6.8 7 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KII88531.1 - 3.8e-05 24.1 7.3 0.095 13.2 0.0 6.9 6 1 1 7 7 7 1 HEAT-like repeat TAN PF11640.8 KII88531.1 - 0.00019 21.6 3.2 0.061 13.4 0.0 5.0 6 0 0 6 6 6 1 Telomere-length maintenance and DNA damage repair Nipped-B_C PF12830.7 KII88531.1 - 0.035 14.1 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 KII88531.1 - 0.036 12.6 0.2 0.94 8.0 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region RTP1_C1 PF10363.9 KII88531.1 - 0.037 14.2 0.0 30 4.9 0.0 4.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KII88531.1 - 1.5 8.3 4.1 19 4.7 0.0 4.6 5 1 2 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II IF-2B PF01008.17 KII88534.1 - 5.1e-57 193.2 0.0 7.2e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4240 PF14024.6 KII88534.1 - 0.066 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Peptidase_M24 PF00557.24 KII88536.1 - 4.2e-51 173.6 0.0 5.9e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KII88536.1 - 3.1e-20 72.2 5.4 5.4e-20 71.4 5.4 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII88536.1 - 0.00021 21.3 3.5 0.00043 20.3 3.5 1.5 1 0 0 1 1 1 1 MYND finger Acyltransferase PF01553.21 KII88537.1 - 2.3e-13 49.9 0.0 8.7e-12 44.8 0.0 2.8 2 1 0 2 2 2 1 Acyltransferase GPDPase_memb PF10110.9 KII88537.1 - 0.25 10.1 1.4 0.42 9.4 1.4 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Cyclin_N PF00134.23 KII88538.1 - 1.7e-14 53.6 0.3 4.4e-14 52.3 0.3 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KII88538.1 - 0.00011 22.2 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 KII88538.1 - 0.00043 20.4 0.0 0.47 10.6 0.0 2.5 2 1 0 2 2 2 2 Cyclin, C-terminal domain DUF4677 PF15726.5 KII88541.1 - 0.28 11.4 3.8 0.37 10.9 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Ribosomal_S21 PF01165.20 KII88543.1 - 5.3e-11 42.1 9.1 5.3e-11 42.1 9.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S21 RWD PF05773.22 KII88544.1 - 6.9e-18 65.0 0.0 1.2e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KII88544.1 - 4e-07 30.4 1.6 1e-06 29.2 1.6 1.6 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Abhydrolase_1 PF00561.20 KII88545.1 - 2.2e-08 34.1 0.0 1.7e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII88545.1 - 5.6e-07 30.4 0.5 8.8e-07 29.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII88545.1 - 0.0036 16.6 0.0 0.057 12.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KII88545.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) zf-CCCH_2 PF14608.6 KII88546.1 - 4.7 7.8 7.1 9.7 6.8 7.1 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Rubis-subs-bind PF09273.11 KII88547.1 - 0.0049 17.6 0.0 0.012 16.4 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 KII88547.1 - 0.0069 16.8 0.0 0.033 14.6 0.0 2.1 2 1 0 2 2 2 1 SET domain adh_short PF00106.25 KII88548.1 - 6.1e-50 169.4 1.8 8.1e-50 169.0 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII88548.1 - 2.7e-31 108.9 2.1 3.3e-31 108.6 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88548.1 - 2.4e-12 47.1 0.8 2.9e-12 46.9 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII88548.1 - 0.011 15.2 0.6 0.011 15.2 0.6 1.6 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KII88548.1 - 0.013 15.3 0.8 0.027 14.2 0.8 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GDP_Man_Dehyd PF16363.5 KII88548.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Helicase_RecD PF05127.14 KII88548.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Helicase DUF1776 PF08643.10 KII88548.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2583 PF10762.9 KII88551.1 - 0.41 11.1 4.5 2.4 8.6 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) YlbE PF14003.6 KII88554.1 - 0.15 12.5 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 YlbE-like protein Lzipper-MIP1 PF14389.6 KII88555.1 - 0.04 14.2 1.0 0.092 13.1 0.4 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.11 KII88555.1 - 0.43 10.7 6.2 0.79 9.8 1.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ATG16 PF08614.11 KII88555.1 - 0.58 10.3 18.6 0.02 15.2 7.6 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DnaJ PF00226.31 KII88557.1 - 1.6e-19 69.8 2.6 1.6e-19 69.8 2.6 1.8 2 0 0 2 2 2 1 DnaJ domain Sec8_exocyst PF04048.14 KII88558.1 - 0.07 13.0 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PLU-1 PF08429.11 KII88558.1 - 0.072 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein HTH_26 PF13443.6 KII88558.1 - 0.17 12.4 0.3 0.4 11.2 0.0 1.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MSC PF09402.10 KII88559.1 - 2.3e-95 319.9 0.0 3e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KII88559.1 - 5.1e-11 42.1 0.0 1.6e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain DUF4194 PF13835.6 KII88559.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) UEV PF05743.13 KII88560.1 - 3.7e-33 113.9 0.0 5.5e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KII88560.1 - 8.2e-29 99.4 1.0 1.4e-28 98.6 0.3 1.8 2 0 0 2 2 2 1 Vps23 core domain CortBP2 PF09727.9 KII88560.1 - 0.0063 16.4 0.5 0.0093 15.9 0.5 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 TEA PF01285.18 KII88561.1 - 3.4e-16 59.1 0.3 6.6e-16 58.2 0.3 1.5 1 0 0 1 1 1 1 TEA/ATTS domain NOC3p PF07540.11 KII88562.1 - 7.1e-32 109.7 0.0 7.1e-32 109.7 0.0 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 KII88562.1 - 7.7e-19 68.4 2.2 2e-18 67.0 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family Pns11_12 PF17464.2 KII88562.1 - 0.58 9.8 6.8 0.36 10.5 0.9 2.3 2 0 0 2 2 2 0 Non-structural protein 11 and 12 AAA_11 PF13086.6 KII88562.1 - 0.72 9.6 4.2 1.4 8.7 4.2 1.4 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.6 KII88562.1 - 0.83 9.8 8.6 1.8 8.6 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ANAPC5 PF12862.7 KII88563.1 - 1.1e-06 28.6 0.1 0.00023 21.2 0.1 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 5 SOBP PF15279.6 KII88566.1 - 0.94 10.0 11.3 1.8 9.1 11.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Conotoxin PF02950.17 KII88566.1 - 5.2 8.2 6.2 9.1 7.4 0.1 3.5 2 1 2 4 4 4 0 Conotoxin Pyr_redox_2 PF07992.14 KII88568.1 - 1.3e-10 41.0 0.0 7.1e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII88568.1 - 0.00012 21.7 0.3 0.021 14.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII88568.1 - 0.0044 17.0 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Kelch_1 PF01344.25 KII88568.1 - 0.0072 15.9 0.5 0.61 9.7 0.0 2.8 3 0 0 3 3 3 1 Kelch motif K_oxygenase PF13434.6 KII88568.1 - 0.19 10.8 1.1 0.23 10.5 0.2 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mso1_Sec1_bdg PF14475.6 KII88569.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Cu_bind_like PF02298.17 KII88570.1 - 8.8e-06 25.7 0.3 2.1e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Adaptin_N PF01602.20 KII88571.1 - 2e-125 419.3 2.4 2.7e-125 418.9 2.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KII88571.1 - 1.1e-53 181.6 0.9 2.9e-51 173.7 0.0 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII88571.1 - 2e-15 57.0 6.7 5.1e-08 33.2 0.9 5.6 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.22 KII88571.1 - 2e-08 33.8 4.7 0.12 12.7 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 KII88571.1 - 0.00015 21.7 4.1 0.23 11.5 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KII88571.1 - 0.0037 16.9 0.1 0.11 12.1 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal Goodbye PF17109.5 KII88571.1 - 0.063 13.7 0.6 16 6.0 0.2 2.7 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain U3snoRNP10 PF12397.8 KII88571.1 - 0.12 12.7 0.0 0.57 10.5 0.0 2.1 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 DUF4477 PF14780.6 KII88572.1 - 2.4e-06 27.3 0.0 2.9e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Ribosomal_60s PF00428.19 KII88573.1 - 0.049 14.2 0.6 0.081 13.5 0.1 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein OTU PF02338.19 KII88574.1 - 1.5e-22 80.4 0.0 3.7e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Aldo_ket_red PF00248.21 KII88575.1 - 5.8e-46 157.0 0.0 6.7e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nexin_C PF08628.12 KII88576.1 - 0.076 13.6 0.0 0.37 11.4 0.0 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal Telomere_reg-2 PF10193.9 KII88576.1 - 0.085 13.3 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Telomere length regulation protein DUF4172 PF13776.6 KII88576.1 - 0.11 12.9 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) ECH_1 PF00378.20 KII88577.1 - 2.9e-23 82.5 0.0 3.5e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII88577.1 - 6.6e-14 52.2 0.0 7.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AA_permease PF00324.21 KII88578.1 - 5.2e-129 430.9 38.0 6.3e-129 430.7 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII88578.1 - 1.2e-31 110.1 40.5 1.5e-31 109.7 40.5 1.2 1 0 0 1 1 1 1 Amino acid permease Pirin PF02678.16 KII88579.1 - 5.9e-30 103.4 0.7 1.1e-29 102.6 0.7 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KII88579.1 - 4.1e-27 94.6 0.1 5.9e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KII88579.1 - 0.35 10.6 2.7 0.77 9.5 1.7 2.1 2 0 0 2 2 2 0 Cupin domain PQQ PF01011.21 KII88580.1 - 0.034 14.1 0.1 0.31 11.0 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat CLTH PF10607.9 KII88581.1 - 9.4e-21 74.3 0.0 1.6e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KII88581.1 - 3.6e-07 30.1 0.1 7.5e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KII88581.1 - 0.00021 20.8 1.2 0.00041 19.8 0.1 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KII88581.1 - 0.0044 16.9 0.3 0.0079 16.1 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 KII88581.1 - 0.008 16.0 1.4 0.073 12.9 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 KII88581.1 - 0.009 16.3 0.3 0.017 15.4 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII88581.1 - 0.02 14.8 0.5 0.04 13.8 0.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KII88581.1 - 0.034 14.0 0.6 0.059 13.2 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII88581.1 - 0.13 12.1 0.3 0.22 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII88581.1 - 0.14 12.0 0.9 0.27 11.1 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sfi1 PF08457.10 KII88582.1 - 6.5e-24 84.4 105.6 2.9e-13 49.3 56.6 4.2 1 1 2 3 3 3 3 Sfi1 spindle body protein Methyltransf_11 PF08241.12 KII88583.1 - 8.1e-06 26.4 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII88583.1 - 1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII88583.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII88583.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88583.1 - 0.0039 17.9 0.0 0.016 15.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Glyco_tran_28_C PF04101.16 KII88584.1 - 1.8e-29 102.9 0.0 2.2e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain P5CR_dimer PF14748.6 KII88585.1 - 6.3e-38 129.2 1.7 1.5e-37 128.0 1.7 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KII88585.1 - 7.9e-12 45.6 0.0 6.9e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Herpes_PAP PF03325.13 KII88585.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein AAA PF00004.29 KII88586.1 - 3e-44 150.6 0.0 9e-44 149.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KII88586.1 - 1e-09 38.2 0.1 6.6e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KII88586.1 - 1.9e-08 34.4 0.1 6.1e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII88586.1 - 7.4e-08 33.0 0.8 3.1e-05 24.4 0.0 2.8 2 2 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KII88586.1 - 8.3e-08 32.5 0.2 3.1e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KII88586.1 - 6e-06 25.6 0.1 1.3e-05 24.5 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KII88586.1 - 4.2e-05 24.1 0.0 0.0019 18.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KII88586.1 - 5.9e-05 23.4 1.0 0.013 15.8 0.1 3.0 2 1 1 3 3 2 1 AAA domain AAA_28 PF13521.6 KII88586.1 - 0.00021 21.5 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KII88586.1 - 0.00028 20.6 0.0 0.00071 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KII88586.1 - 0.00038 20.5 0.0 0.0022 18.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KII88586.1 - 0.00057 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KII88586.1 - 0.00073 19.5 0.0 0.016 15.2 0.0 2.4 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KII88586.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 KII88586.1 - 0.0021 18.2 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII88586.1 - 0.0025 17.5 0.4 0.0069 16.1 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KII88586.1 - 0.0032 17.0 0.1 0.027 14.0 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KII88586.1 - 0.0044 16.8 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KII88586.1 - 0.0047 16.2 0.0 0.0093 15.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 KII88586.1 - 0.0061 16.5 1.8 0.015 15.2 0.0 2.5 4 0 0 4 4 3 1 NTPase TniB PF05621.11 KII88586.1 - 0.0078 15.6 0.6 0.58 9.5 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 KII88586.1 - 0.0086 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KII88586.1 - 0.013 15.5 0.1 0.088 12.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KII88586.1 - 0.015 14.9 0.6 0.055 13.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 KII88586.1 - 0.015 15.1 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KII88586.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 KII88586.1 - 0.03 14.4 3.0 0.059 13.4 3.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_19 PF13245.6 KII88586.1 - 0.044 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KII88586.1 - 0.047 13.5 0.2 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KII88586.1 - 0.059 12.2 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 KII88586.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KII88586.1 - 0.096 12.4 0.2 1.1 9.0 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain ATPase PF06745.13 KII88586.1 - 0.12 11.7 0.5 0.51 9.6 0.0 2.1 3 0 0 3 3 3 0 KaiC DnaB_C PF03796.15 KII88586.1 - 0.12 11.6 2.4 4 6.7 0.4 2.8 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 KII88586.1 - 0.14 12.7 0.2 0.68 10.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KII88586.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KII88586.1 - 0.17 11.8 1.8 0.6 10.0 0.1 2.7 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KII88587.1 - 1.5e-11 43.9 0.1 7.8e-11 41.7 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L14e PF01929.17 KII88589.1 - 1.7e-31 108.5 0.8 2.7e-31 107.9 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KII88589.1 - 5.6e-06 26.1 2.9 5.6e-06 26.1 0.2 2.1 2 0 0 2 2 2 1 KOW motif DUF2561 PF10812.8 KII88590.1 - 0.061 13.4 1.1 0.091 12.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SNRNP27 PF08648.12 KII88591.1 - 1.6e-29 101.7 1.1 2.7e-29 101.0 1.1 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 KII88592.1 - 4.3e-28 97.6 0.4 5.6e-28 97.3 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Nop53 PF07767.11 KII88593.1 - 0.0091 15.4 12.9 0.011 15.1 12.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CSRNP_N PF16019.5 KII88593.1 - 0.16 11.9 1.6 0.19 11.6 1.0 1.3 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CDC45 PF02724.14 KII88593.1 - 0.21 9.8 2.1 0.24 9.7 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.12 KII88593.1 - 0.32 8.8 0.4 0.42 8.4 0.4 1.0 1 0 0 1 1 1 0 Ycf1 EBV-NA3 PF05009.12 KII88593.1 - 0.67 9.4 3.1 0.97 8.9 3.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Peptidase_S30 PF01577.16 KII88593.1 - 2.1 7.9 6.3 3.2 7.3 6.3 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease PPP4R2 PF09184.11 KII88594.1 - 2.5e-15 56.9 7.6 8.6e-15 55.1 7.6 2.0 1 1 0 1 1 1 1 PPP4R2 PAP2 PF01569.21 KII88595.1 - 5.5e-31 107.2 2.2 1.1e-30 106.1 2.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KII88595.1 - 0.051 13.5 0.4 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Ribosomal_S21e PF01249.18 KII88596.1 - 3.9e-39 132.6 0.1 4.4e-39 132.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NTF2 PF02136.20 KII88596.1 - 0.082 13.5 0.0 0.089 13.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4426 PF14467.6 KII88596.1 - 0.1 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) adh_short PF00106.25 KII88597.1 - 2.4e-26 92.4 0.1 5.1e-21 75.0 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII88597.1 - 9.5e-18 64.6 0.3 2.8e-16 59.8 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88597.1 - 1.8e-09 37.8 0.0 3.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII88597.1 - 0.00036 20.1 0.4 0.00081 18.9 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII88597.1 - 0.0033 16.9 0.0 0.0067 15.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KII88597.1 - 0.0062 16.8 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KII88597.1 - 0.012 15.6 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2807 PF10988.8 KII88597.1 - 0.035 13.9 0.6 0.058 13.2 0.6 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain AdoHcyase_NAD PF00670.21 KII88597.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F-box-like PF12937.7 KII88598.1 - 6e-07 29.3 2.1 1.5e-06 28.0 2.1 1.8 1 0 0 1 1 1 1 F-box-like RabGAP-TBC PF00566.18 KII88599.1 - 1.7e-42 145.5 5.0 1.1e-40 139.6 1.6 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 KII88599.1 - 2.5e-09 36.8 0.0 6.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Rab-binding domain (RBD) zf-C2HE PF16278.5 KII88600.1 - 1.6e-14 54.1 2.1 5e-14 52.5 2.1 1.9 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KII88600.1 - 7.2e-13 49.0 0.8 1.2e-12 48.3 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KII88600.1 - 3.3e-09 37.4 0.0 8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain zf-C2H2_12 PF18658.1 KII88600.1 - 0.0032 17.0 1.3 0.0042 16.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger C2H2-type ox_reductase_C PF08635.10 KII88601.1 - 4.6e-72 240.3 0.2 6.7e-72 239.7 0.2 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KII88601.1 - 2.4e-23 83.2 0.2 7.2e-23 81.7 0.0 1.9 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII88601.1 - 0.0022 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SKA2 PF16740.5 KII88602.1 - 0.0046 16.7 1.4 0.0069 16.2 1.4 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 UPF0242 PF06785.11 KII88602.1 - 0.014 15.5 1.4 0.014 15.5 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KII88602.1 - 0.019 15.2 2.3 0.032 14.4 2.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Rx_N PF18052.1 KII88602.1 - 0.026 14.8 3.2 0.041 14.2 3.2 1.2 1 0 0 1 1 1 0 Rx N-terminal domain DUF489 PF04356.12 KII88602.1 - 0.037 14.0 0.1 0.04 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) YabA PF06156.13 KII88602.1 - 0.17 12.5 1.9 0.22 12.2 1.9 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KII88602.1 - 0.26 11.1 5.9 0.37 10.6 5.9 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 KII88602.1 - 1.1 9.7 4.9 1.5 9.3 4.6 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CBM_48 PF02922.18 KII88603.1 - 0.024 15.0 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PIG-Y PF15159.6 KII88604.1 - 1.4e-21 77.1 4.5 1.6e-21 77.0 4.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Aminotran_1_2 PF00155.21 KII88605.1 - 3e-83 280.0 0.0 3.4e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.16 KII88606.1 - 2.9e-10 40.1 6.8 2.9e-10 40.1 6.8 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KII88606.1 - 0.0053 16.5 0.6 0.0053 16.5 0.6 2.3 2 0 0 2 2 2 1 Rubredoxin metal binding domain IBR PF01485.21 KII88606.1 - 0.032 14.5 8.1 0.043 14.0 7.7 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain ERO1 PF04137.15 KII88606.1 - 0.093 11.9 4.7 0.099 11.8 4.7 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Syntaxin PF00804.25 KII88608.1 - 2.2e-33 115.6 6.7 3e-33 115.2 6.7 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KII88608.1 - 2.4e-08 33.8 0.8 2.4e-08 33.8 0.8 2.4 1 1 1 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KII88608.1 - 8.1e-06 26.1 3.3 8.1e-06 26.1 3.3 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Tweety PF04906.13 KII88608.1 - 0.0013 17.5 1.2 0.0087 14.8 0.2 2.1 2 0 0 2 2 2 1 Tweety Use1 PF09753.9 KII88608.1 - 0.0023 17.7 2.0 0.0034 17.1 2.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCPsignal PF00015.21 KII88608.1 - 0.0028 17.5 1.6 0.0083 16.0 0.9 2.0 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.10 KII88608.1 - 0.0094 15.9 0.2 0.049 13.6 0.1 2.0 2 0 0 2 2 2 1 Vitamin D binding protein, domain III SF3a60_bindingd PF12108.8 KII88608.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain ABC2_membrane_3 PF12698.7 KII88608.1 - 0.11 11.5 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ODV-E18 PF10717.9 KII88608.1 - 0.12 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DASH_Dam1 PF08653.10 KII88608.1 - 0.13 12.1 0.3 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 TPPK_C PF12555.8 KII88608.1 - 0.13 12.3 1.3 0.29 11.2 1.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF805 PF05656.14 KII88608.1 - 0.16 12.4 0.5 0.68 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF4407 PF14362.6 KII88608.1 - 0.16 11.3 6.4 0.51 9.6 5.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spectrin PF00435.21 KII88608.1 - 0.16 12.4 3.4 8.7 6.9 0.2 2.8 3 0 0 3 3 2 0 Spectrin repeat DUF2207 PF09972.9 KII88608.1 - 0.2 10.4 3.0 0.23 10.2 0.8 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Pox_EPC_I2-L1 PF12575.8 KII88608.1 - 0.21 11.9 1.3 0.51 10.6 1.3 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 NAP PF00956.18 KII88608.1 - 0.26 10.4 3.3 0.43 9.7 3.3 1.4 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Pox_A_type_inc PF04508.12 KII88608.1 - 0.3 11.0 3.7 1.1 9.3 1.5 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Orf78 PF06024.12 KII88608.1 - 0.39 11.0 1.7 0.83 10.0 1.3 1.8 1 1 0 1 1 1 0 Orf78 (ac78) DUF745 PF05335.13 KII88608.1 - 2.2 8.0 6.0 0.55 9.9 1.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Synaptobrevin PF00957.21 KII88608.1 - 3 7.7 12.8 0.86 9.4 6.6 2.7 2 1 0 2 2 2 0 Synaptobrevin V-SNARE PF05008.15 KII88608.1 - 5.3 7.5 12.2 0.19 12.1 0.5 3.2 2 1 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus CLZ PF16526.5 KII88608.1 - 6.7 7.1 8.6 8.1 6.9 0.1 3.6 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Hexapep PF00132.24 KII88609.1 - 2e-12 46.3 12.9 2.8e-05 23.6 2.6 3.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KII88609.1 - 2.8e-09 36.9 0.0 4.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.18 KII88609.1 - 3e-09 36.9 0.0 3e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.12 KII88609.1 - 8.5e-07 28.2 0.7 1.4e-06 27.5 0.7 1.2 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KII88609.1 - 8.3e-05 22.3 13.4 0.017 14.9 3.2 3.6 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KII88609.1 - 0.00042 20.7 1.4 0.00074 19.9 0.0 2.2 3 0 0 3 3 3 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KII88609.1 - 0.022 12.9 2.7 0.034 12.3 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Pmp3 PF01679.17 KII88610.1 - 6.8e-25 87.0 8.6 7.7e-25 86.9 8.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Abhydrolase_3 PF07859.13 KII88611.1 - 1.7e-07 31.3 0.3 3.9e-07 30.1 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII88611.1 - 0.072 12.3 0.2 2.7 7.2 0.0 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 KII88611.1 - 0.074 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.21 KII88611.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_5 PF00266.19 KII88612.1 - 3.7e-14 52.5 0.0 5.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.19 KII88613.1 - 1.2e-21 77.4 0.0 2.5e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII88613.1 - 5.5e-06 26.2 0.0 0.016 14.8 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII88613.1 - 3e-05 24.5 0.0 0.00061 20.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII88613.1 - 0.0001 21.7 0.0 0.00068 19.0 0.0 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII88613.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KII88613.1 - 0.0031 17.7 0.1 0.0098 16.1 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KII88613.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KII88613.1 - 0.013 14.2 0.5 0.024 13.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 KII88613.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 KII88613.1 - 0.023 13.8 0.0 0.09 11.8 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 KII88613.1 - 0.029 13.2 0.0 3.9 6.2 0.2 2.9 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.21 KII88613.1 - 0.045 13.1 0.2 0.096 12.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.6 KII88613.1 - 0.081 13.4 0.0 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 KII88613.1 - 0.12 11.6 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII88613.1 - 0.13 11.3 0.2 0.22 10.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 KII88613.1 - 0.17 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AT_hook PF02178.19 KII88614.1 - 0.00023 20.7 55.1 0.14 12.1 6.9 4.5 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.13 KII88615.1 - 1e-13 52.1 0.0 2.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KII88615.1 - 2.5e-06 27.3 0.0 1.5e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 KII88616.1 - 8.3e-38 130.3 0.0 1.8e-36 125.9 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88616.1 - 5.7e-20 71.7 0.0 1.4e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII88616.1 - 0.0038 17.2 0.2 0.011 15.6 0.2 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KII88616.1 - 0.098 12.3 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KII88616.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GST_N_3 PF13417.6 KII88619.1 - 1.1e-11 44.9 0.2 3.1e-11 43.5 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII88619.1 - 7.4e-11 42.2 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII88619.1 - 5.6e-05 23.1 0.7 0.00021 21.2 0.1 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII88619.1 - 0.00031 20.9 0.0 0.0008 19.6 0.0 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII88619.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KII88619.1 - 0.029 14.7 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KII88619.1 - 0.039 14.7 0.0 0.083 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 KII88621.1 - 3.6e-13 49.7 0.0 8.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII88621.1 - 2.5e-10 40.5 0.0 5.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII88621.1 - 8e-06 25.8 0.1 1.8e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII88621.1 - 0.00029 21.0 0.0 0.00078 19.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII88621.1 - 0.00086 19.5 0.0 0.004 17.3 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KII88621.1 - 0.0046 17.3 0.0 0.046 14.1 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KII88621.1 - 0.046 14.3 0.0 0.098 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KII88621.1 - 0.068 13.5 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KII88621.1 - 0.081 13.7 0.0 0.53 11.1 0.0 2.3 2 1 0 3 3 3 0 Glutathione S-transferase N-terminal domain PIG-H PF10181.9 KII88622.1 - 7.8e-18 64.1 0.0 1.1e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ist1 PF03398.14 KII88623.1 - 1.1e-41 142.5 0.0 1.7e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KII88623.1 - 3.9e-10 39.8 0.2 4.5e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ion_trans PF00520.31 KII88625.1 - 0.00034 19.9 0.3 0.00047 19.5 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein YabA PF06156.13 KII88625.1 - 0.044 14.4 1.0 0.061 14.0 1.0 1.2 1 0 0 1 1 1 0 Initiation control protein YabA MctB PF11382.8 KII88625.1 - 0.048 13.4 0.7 0.069 12.8 0.7 1.1 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Complex1_49kDa PF00346.19 KII88625.1 - 0.18 10.9 0.2 0.51 9.4 0.1 1.7 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DivIC PF04977.15 KII88625.1 - 0.58 10.0 3.0 1 9.2 3.0 1.3 1 0 0 1 1 1 0 Septum formation initiator NAC PF01849.18 KII88627.1 - 7.9e-20 70.6 0.0 1.5e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 KII88627.1 - 0.017 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF1264 PF06884.11 KII88628.1 - 3.1e-69 232.0 0.2 3.8e-69 231.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DivIC PF04977.15 KII88629.1 - 0.045 13.5 0.5 0.045 13.5 0.5 4.8 4 1 1 5 5 5 0 Septum formation initiator HSP90 PF00183.18 KII88630.1 - 3.1e-230 765.5 22.6 3.8e-230 765.2 22.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KII88630.1 - 4.6e-14 52.9 0.0 8.7e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KII88630.1 - 1.9e-09 37.5 0.1 5.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 KII88630.1 - 0.07 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF2052 PF09747.9 KII88630.1 - 1.9 8.6 13.4 1.3 9.2 8.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Aminotran_5 PF00266.19 KII88633.1 - 9.8e-38 130.1 0.0 1.3e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TRAPPC10 PF12584.8 KII88634.1 - 1e-35 122.7 0.0 1.9e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Thioredoxin_8 PF13905.6 KII88634.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like DEAD PF00270.29 KII88635.1 - 1e-48 165.5 0.0 1.6e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII88635.1 - 6.1e-32 110.3 0.2 1.6e-31 108.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII88635.1 - 7.8e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KII88635.1 - 6.8e-05 22.2 0.1 9.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TMEM238 PF15125.6 KII88636.1 - 0.17 12.1 0.3 0.17 12.1 0.3 1.8 2 0 0 2 2 2 0 TMEM238 protein family Methyltransf_7 PF03492.15 KII88636.1 - 0.21 10.8 0.1 0.23 10.6 0.1 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase 2OG-FeII_Oxy_3 PF13640.6 KII88638.1 - 3.8e-06 27.7 0.0 6.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Far-17a_AIG1 PF04750.14 KII88639.1 - 1e-32 113.1 5.4 1.2e-32 112.9 5.4 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4689 PF15755.5 KII88639.1 - 0.061 12.9 0.6 0.098 12.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) DUF1218 PF06749.12 KII88639.1 - 1.5 9.4 6.5 7.6 7.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) GST_N_3 PF13417.6 KII88641.1 - 9.9e-13 48.3 0.0 2.1e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII88641.1 - 7e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII88641.1 - 1e-06 28.7 0.3 3.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII88641.1 - 0.00013 22.1 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII88641.1 - 0.0044 17.2 0.0 0.014 15.5 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KII88641.1 - 0.03 14.7 0.0 0.36 11.2 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KII88641.1 - 0.053 14.3 0.0 0.1 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain FUN14 PF04930.15 KII88642.1 - 1.9e-19 69.9 2.7 1.9e-19 69.9 2.7 1.6 2 0 0 2 2 2 1 FUN14 family Dscam_C PF12355.8 KII88642.1 - 0.18 12.8 2.2 0.33 11.9 2.2 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DNA_primase_lrg PF04104.14 KII88643.1 - 1.7e-88 296.5 0.0 2.7e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Syntaxin PF00804.25 KII88644.1 - 1.1e-33 116.6 7.9 1.6e-33 116.1 7.9 1.2 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KII88644.1 - 4.7e-10 39.3 1.4 1.7e-09 37.6 1.4 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KII88644.1 - 2.5e-05 24.6 6.0 2.5e-05 24.6 6.0 2.3 2 0 0 2 2 2 1 Syntaxin-like protein VitD-bind_III PF09164.10 KII88644.1 - 0.0011 19.0 0.8 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 Vitamin D binding protein, domain III MCPsignal PF00015.21 KII88644.1 - 0.0014 18.4 3.7 0.0095 15.8 0.8 2.4 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.21 KII88644.1 - 0.042 14.3 5.8 0.49 10.9 0.2 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF2939 PF11159.8 KII88644.1 - 0.08 13.4 1.6 0.24 11.8 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Tweety PF04906.13 KII88644.1 - 0.089 11.4 6.2 0.4 9.3 0.7 2.4 2 1 0 2 2 2 0 Tweety LRR19-TM PF15176.6 KII88644.1 - 0.14 12.1 2.7 0.44 10.6 2.7 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain ALMT PF11744.8 KII88644.1 - 0.15 10.9 5.2 0.24 10.2 5.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF745 PF05335.13 KII88644.1 - 0.18 11.5 8.8 0.23 11.2 1.3 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Pox_A_type_inc PF04508.12 KII88644.1 - 0.21 11.5 3.7 0.97 9.4 1.5 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FUSC PF04632.12 KII88644.1 - 0.32 9.5 2.6 0.36 9.3 1.8 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Herpes_US9 PF06072.11 KII88644.1 - 0.86 9.5 2.9 2.1 8.3 2.9 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DASH_Dam1 PF08653.10 KII88644.1 - 1.2 9.0 3.2 1.4 8.7 0.3 2.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 KII88644.1 - 1.2 9.7 5.8 30 5.3 2.6 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal WXG100 PF06013.12 KII88644.1 - 1.9 8.8 9.2 9 6.6 0.1 3.5 2 2 1 3 3 3 0 Proteins of 100 residues with WXG Ibs_toxin PF13956.6 KII88644.1 - 4.7 7.3 8.3 8.2 6.6 8.3 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system CdvA PF18822.1 KII88644.1 - 5 7.0 10.0 1.6 8.6 0.8 3.5 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Lyase_1 PF00206.20 KII88645.1 - 6.7e-101 337.8 0.0 9.8e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KII88645.1 - 1.2e-24 86.8 0.1 2.9e-24 85.6 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Cellulase PF00150.18 KII88646.1 - 2.4e-13 50.1 0.4 4.1e-13 49.4 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SR-25 PF10500.9 KII88646.1 - 0.29 10.7 3.7 7.4 6.1 6.1 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 KII88646.1 - 0.35 11.1 8.2 0.67 10.2 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ALG3 PF05208.13 KII88647.1 - 1e-138 462.7 9.2 1.2e-138 462.5 9.2 1.0 1 0 0 1 1 1 1 ALG3 protein DUF3146 PF11344.8 KII88647.1 - 0.19 11.4 0.7 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) MFS_1 PF07690.16 KII88648.1 - 2.1e-13 49.9 41.9 2.5e-13 49.7 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KII88648.1 - 1.2e-08 34.7 3.2 1.2e-08 34.7 3.2 2.2 3 0 0 3 3 3 1 Nodulin-like HEAT PF02985.22 KII88649.1 - 4e-19 67.1 9.0 5.7e-05 23.0 0.1 8.6 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 KII88649.1 - 6.3e-13 48.9 15.9 7.7e-05 23.0 0.2 7.3 6 1 0 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 KII88649.1 - 2.5e-05 24.7 17.8 0.025 15.1 0.8 7.2 5 2 1 6 6 6 3 HEAT-like repeat MARVEL PF01284.23 KII88650.1 - 2 8.4 15.2 3.2 7.8 15.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain Aldo_ket_red PF00248.21 KII88651.1 - 8.3e-55 186.0 0.0 9.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syntaxin PF00804.25 KII88653.1 - 8.9e-29 100.6 8.6 1.4e-28 100.0 8.6 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KII88653.1 - 2.8e-11 43.2 2.2 3.8e-11 42.8 0.8 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KII88653.1 - 5.1e-10 39.6 17.1 1.9e-09 37.8 9.1 2.2 2 0 0 2 2 2 2 Syntaxin-like protein FUSC PF04632.12 KII88653.1 - 0.0013 17.4 3.8 0.0013 17.4 3.8 1.5 2 0 0 2 2 2 1 Fusaric acid resistance protein family Prominin PF05478.11 KII88653.1 - 0.0057 14.7 0.1 0.0057 14.7 0.1 2.0 2 0 0 2 2 2 1 Prominin Mod_r PF07200.13 KII88653.1 - 0.011 15.9 13.0 0.11 12.6 6.7 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein V-SNARE PF05008.15 KII88653.1 - 0.012 15.9 0.2 0.012 15.9 0.2 3.5 2 1 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus EVI2A PF05399.11 KII88653.1 - 0.028 14.0 3.1 0.043 13.4 0.0 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) SKA1 PF07160.12 KII88653.1 - 0.033 14.0 10.5 0.075 12.9 0.4 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 VitD-bind_III PF09164.10 KII88653.1 - 0.098 12.7 0.3 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Allexi_40kDa PF05549.11 KII88653.1 - 0.31 10.5 7.1 0.12 11.9 1.6 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Herpes_US9 PF06072.11 KII88653.1 - 0.31 10.9 1.3 0.76 9.7 1.3 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 MCPsignal PF00015.21 KII88653.1 - 0.72 9.6 9.8 0.12 12.2 2.0 2.7 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PET10 PF17316.2 KII88653.1 - 0.77 9.2 3.5 1.3 8.4 3.4 1.4 1 1 0 1 1 1 0 Petite colonies protein 10 BLOC1_2 PF10046.9 KII88653.1 - 0.96 9.8 7.1 1.2 9.4 0.3 3.4 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 KII88653.1 - 2.2 8.1 10.3 0.27 11.0 2.9 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Plk4_PB2 PF18409.1 KII88653.1 - 2.3 9.0 7.0 28 5.4 0.5 3.2 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 DUF2203 PF09969.9 KII88653.1 - 8.6 7.1 7.6 7.3 7.3 1.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Rsd_AlgQ PF04353.13 KII88653.1 - 9.3 6.2 8.8 3.5 7.6 0.6 3.0 3 1 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ CDP-OH_P_transf PF01066.21 KII88654.1 - 2.5e-13 50.6 0.2 2.5e-13 50.6 0.2 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Flavodoxin_NdrI PF07972.11 KII88654.1 - 0.055 13.6 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 NrdI Flavodoxin like AAA PF00004.29 KII88655.1 - 1.5e-35 122.5 0.0 2.9e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII88655.1 - 2.6e-09 36.7 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KII88655.1 - 7.9e-05 23.1 0.9 0.0071 16.8 0.1 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KII88655.1 - 0.00044 20.3 0.0 0.0019 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII88655.1 - 0.0017 18.6 0.3 0.037 14.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KII88655.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KII88655.1 - 0.011 14.8 0.3 0.037 13.0 0.0 1.8 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KII88655.1 - 0.015 15.8 0.1 0.067 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KII88655.1 - 0.023 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KII88655.1 - 0.028 14.2 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KII88655.1 - 0.04 13.7 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KII88655.1 - 0.065 13.5 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KII88655.1 - 0.065 12.4 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 KII88655.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KII88655.1 - 0.086 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 KII88655.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KII88655.1 - 0.17 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII88655.1 - 0.24 11.8 0.0 0.48 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SMC_Nse1 PF07574.13 KII88656.1 - 6.2e-25 88.2 0.4 3.6e-23 82.5 0.4 2.0 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DUF1348 PF07080.11 KII88657.1 - 2.8e-57 192.2 4.7 3.3e-57 192.0 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KII88657.1 - 0.00011 22.8 0.3 0.00016 22.2 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KII88657.1 - 0.0031 17.9 0.0 0.0044 17.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3648 PF12364.8 KII88657.1 - 0.051 13.8 0.1 0.24 11.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) Pectate_lyase_3 PF12708.7 KII88660.1 - 4.9e-98 327.2 20.4 8.7e-85 283.9 11.3 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KII88660.1 - 1.9e-09 37.1 2.1 0.00074 19.2 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Pectate_lyase_3 PF12708.7 KII88661.1 - 2.7e-98 328.1 17.4 9.3e-85 283.8 6.4 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KII88661.1 - 5.7e-08 32.3 1.5 0.01 15.5 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase SpaA PF17802.1 KII88661.1 - 0.13 12.7 0.4 0.69 10.3 0.0 2.5 2 0 0 2 2 2 0 Prealbumin-like fold domain CDC45 PF02724.14 KII88662.1 - 9.9e-214 711.3 0.0 1.1e-213 711.1 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein RBM1CTR PF08081.11 KII88662.1 - 0.037 14.1 3.8 0.1 12.7 3.8 1.8 1 0 0 1 1 1 0 RBM1CTR (NUC064) family NOA36 PF06524.12 KII88662.1 - 1 8.6 2.9 1.5 8.1 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein Scramblase PF03803.15 KII88665.1 - 1.1e-56 191.6 0.0 5.2e-56 189.4 0.0 1.8 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.27 KII88666.1 - 3.5e-34 118.0 3.1 1.8e-32 112.5 3.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KII88666.1 - 2.8e-27 94.9 1.1 1.2e-26 92.9 0.2 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KII88666.1 - 2.9e-08 33.8 0.5 8.3e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KII88666.1 - 0.00059 19.6 0.3 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KII88666.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KII88666.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CHORD PF04968.12 KII88667.1 - 4.2e-49 165.1 14.8 5e-25 88.0 4.7 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 KII88667.1 - 2.6e-12 47.6 0.0 4.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 CS domain BTK PF00779.19 KII88667.1 - 0.0053 16.5 4.6 3.2 7.6 0.1 3.8 3 0 0 3 3 3 2 BTK motif Rieske PF00355.26 KII88667.1 - 0.093 12.7 0.7 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Mito_carr PF00153.27 KII88668.1 - 6.7e-10 38.8 0.1 0.0011 18.8 0.0 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.6 KII88669.1 - 3.2e-13 50.3 0.0 4.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 KII88670.1 - 5.5e-09 35.8 0.0 0.0012 18.4 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII88670.1 - 2.8e-05 23.8 0.0 0.0049 16.5 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 KII88672.1 - 2e-40 136.0 17.0 4.3e-11 43.2 0.2 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88672.1 - 3.8e-16 59.2 2.6 0.00023 21.4 0.0 5.3 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII88672.1 - 5.7e-07 28.8 1.9 0.21 10.5 0.0 4.2 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KII88672.1 - 4.5e-06 25.6 3.3 0.32 9.6 0.1 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 KII88672.1 - 0.00013 21.8 0.1 0.51 10.0 0.0 2.7 2 1 1 3 3 3 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KII88672.1 - 0.0005 18.9 1.4 0.02 13.7 0.1 3.6 1 1 4 5 5 5 1 Nup133 N terminal like PALB2_WD40 PF16756.5 KII88672.1 - 0.0025 16.8 0.1 0.0025 16.8 0.1 2.2 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KII88672.1 - 0.05 11.9 0.0 0.08 11.2 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz GATase_2 PF00310.21 KII88674.1 - 1.1e-177 591.0 0.0 1.5e-177 590.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KII88674.1 - 1.2e-154 514.9 1.0 1.4e-154 514.7 0.1 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KII88674.1 - 9.6e-112 373.0 0.0 7.3e-110 366.8 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KII88674.1 - 9.4e-88 292.8 4.3 1.6e-87 292.0 4.3 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KII88674.1 - 4e-25 88.6 0.0 1.9e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KII88674.1 - 1e-22 80.1 0.1 2e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 KII88674.1 - 9.9e-10 38.9 0.1 2.6e-05 24.7 0.0 4.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII88674.1 - 1.9e-09 37.2 0.6 0.014 14.7 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII88674.1 - 6e-09 36.0 0.0 2.7e-08 33.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII88674.1 - 2.1e-07 30.9 0.1 0.0023 17.5 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KII88674.1 - 3.2e-06 26.1 0.7 7.4e-06 24.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KII88674.1 - 6.3e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KII88674.1 - 0.00045 19.4 0.0 0.00045 19.4 0.0 2.7 3 0 0 3 3 2 1 FAD binding domain FMN_dh PF01070.18 KII88674.1 - 0.0011 18.1 1.4 0.0048 16.0 1.2 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_oxidored PF12831.7 KII88674.1 - 0.0016 17.9 0.1 0.0016 17.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII88674.1 - 0.0017 17.7 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KII88674.1 - 0.002 17.3 0.1 0.22 10.5 0.0 2.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KII88674.1 - 0.0057 17.1 0.7 0.97 9.9 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KII88674.1 - 0.0073 15.6 0.0 0.81 8.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KII88674.1 - 0.018 15.1 0.5 7.7 6.6 0.1 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.6 KII88674.1 - 0.02 15.1 0.1 0.32 11.2 0.1 2.7 3 0 0 3 3 3 0 Glutamine amidotransferase domain FMO-like PF00743.19 KII88674.1 - 0.022 13.2 0.1 6.6 5.0 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 KII88674.1 - 0.026 13.8 0.1 0.026 13.8 0.1 1.9 2 0 0 2 2 2 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 KII88674.1 - 0.044 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 KII88674.1 - 0.06 12.7 0.0 0.25 10.7 0.0 2.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KII88674.1 - 0.073 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KII88674.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 KII88674.1 - 0.095 12.9 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 KII88674.1 - 0.098 11.7 1.8 0.37 9.8 0.1 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KII88674.1 - 0.11 12.4 0.4 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KII88674.1 - 0.17 11.4 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TraQ PF09679.10 KII88675.1 - 2.3 8.2 4.8 0.43 10.5 0.2 2.1 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF3487 PF11990.8 KII88675.1 - 7.6 6.4 7.8 1.1 9.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF743 PF05332.11 KII88676.1 - 0.012 15.6 0.3 0.025 14.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Ribonuclease_3 PF00636.26 KII88676.1 - 0.089 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain Acetyltransf_13 PF13880.6 KII88677.1 - 1e-13 51.0 0.0 1.9e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KII88677.1 - 1e-08 34.8 0.2 1.8e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KII88677.1 - 0.031 14.7 0.0 0.086 13.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Mss51 PF13824.6 KII88679.1 - 9.2e-24 83.3 13.5 1.6e-23 82.5 13.5 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.11 KII88679.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Lar_restr_allev PF14354.6 KII88679.1 - 0.17 12.3 4.4 0.36 11.2 4.4 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar IGPD PF00475.18 KII88680.1 - 1.5e-59 200.4 0.1 2.3e-59 199.8 0.1 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase 3-HAO PF06052.12 KII88682.1 - 2.8e-60 202.3 0.0 3.2e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KII88682.1 - 1.9e-06 27.5 0.1 3.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KII88682.1 - 0.00044 20.2 0.1 0.00078 19.4 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KII88682.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupin POPLD PF08170.12 KII88683.1 - 0.11 12.8 5.0 0.31 11.4 0.4 3.0 2 1 1 3 3 3 0 POPLD (NUC188) domain Peptidase_M13_N PF05649.13 KII88684.1 - 2e-99 333.9 0.0 2.8e-99 333.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KII88684.1 - 5.5e-59 199.2 0.4 8.3e-59 198.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Mucin PF01456.17 KII88684.1 - 0.001 19.1 13.6 0.002 18.1 13.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein 2OG-FeII_Oxy_2 PF13532.6 KII88685.1 - 1e-25 91.1 0.0 1.6e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_8 PF02954.19 KII88685.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family UBA PF00627.31 KII88685.1 - 0.16 11.9 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Peptidase_M24 PF00557.24 KII88686.1 - 1.6e-46 158.6 0.5 6.4e-46 156.7 0.4 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KII88686.1 - 0.00023 21.8 0.0 0.00037 21.1 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Mal_decarbox_Al PF16957.5 KII88686.1 - 0.04 12.2 0.3 0.077 11.3 0.0 1.5 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter HAD_2 PF13419.6 KII88688.1 - 5.3e-07 29.9 0.0 9.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII88688.1 - 0.00021 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KII88688.1 - 0.00082 19.7 0.0 0.01 16.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KII88688.1 - 0.044 13.6 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase QCR10 PF09796.9 KII88689.1 - 5.1e-18 64.9 0.1 5.4e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) IMS_HHH PF11798.8 KII88689.1 - 0.15 12.4 0.0 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 IMS family HHH motif Nop16 PF09420.10 KII88690.1 - 4.8e-57 193.4 0.1 5.5e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Zn_clus PF00172.18 KII88691.1 - 4.8e-06 26.6 4.3 1e-05 25.5 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KII88692.1 - 6.4e-77 258.9 0.0 9.1e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII88692.1 - 0.0089 17.0 0.0 0.019 15.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.32 KII88693.1 - 2.4e-21 73.6 0.2 1.1e-05 24.6 0.0 4.7 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KII88693.1 - 8.4e-19 65.8 0.7 2e-05 24.1 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KII88693.1 - 9.2e-16 56.5 0.1 0.00011 21.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KII88693.1 - 2.4e-15 56.7 0.1 3.6e-06 27.3 0.0 3.1 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KII88693.1 - 1.1e-11 44.4 0.6 0.00015 21.5 0.2 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 KII88693.1 - 0.17 12.2 0.0 60 4.1 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain F-box-like PF12937.7 KII88694.1 - 2.8e-09 36.7 1.2 1.3e-08 34.6 1.2 2.3 1 0 0 1 1 1 1 F-box-like DUF484 PF04340.12 KII88694.1 - 0.053 13.2 0.3 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 USP8_interact PF08941.10 KII88694.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 USP8 interacting F_bP_aldolase PF01116.20 KII88695.1 - 8.6e-93 310.9 0.0 9.6e-93 310.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AdoHcyase PF05221.17 KII88695.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase CPSase_L_D2 PF02786.17 KII88695.1 - 0.15 11.5 0.4 0.39 10.2 0.3 1.7 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain dCMP_cyt_deam_1 PF00383.23 KII88696.1 - 6.1e-17 61.4 0.0 9e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII88696.1 - 8.4e-16 58.0 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KII88696.1 - 0.00023 21.3 0.0 0.00075 19.6 0.0 1.7 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KII88696.1 - 0.0057 16.7 0.7 0.23 11.5 0.7 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 KII88696.1 - 0.018 15.2 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 KII88696.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 APOBEC2 NAD2 PF18782.1 KII88696.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 KII88696.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 KII88696.1 - 0.15 11.9 0.1 0.22 11.4 0.1 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Transp_cyt_pur PF02133.15 KII88697.1 - 1.1e-42 146.4 35.7 1.4e-42 146.0 35.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pam17 PF08566.10 KII88697.1 - 7.5 6.4 6.3 0.46 10.3 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 AMP-binding PF00501.28 KII88699.1 - 8.6e-88 294.7 0.0 1.2e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII88699.1 - 0.0011 19.9 0.5 0.0034 18.3 0.5 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KII88700.1 - 1e-30 106.9 25.9 1e-30 106.9 25.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII88700.1 - 5.6e-09 35.4 4.5 5.6e-09 35.4 4.5 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter VQ PF05678.14 KII88700.1 - 0.015 14.7 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 VQ motif OAD_gamma PF04277.13 KII88700.1 - 0.52 10.9 2.5 9.3 6.9 0.1 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2530 PF10745.9 KII88700.1 - 1.5 9.1 5.3 0.54 10.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SOR_SNZ PF01680.17 KII88702.1 - 1.8e-109 364.3 5.8 2.9e-109 363.7 5.8 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KII88702.1 - 5.2e-09 35.8 7.9 1.5e-07 31.0 0.1 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KII88702.1 - 1.1e-05 24.7 0.5 0.065 12.3 0.1 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KII88702.1 - 0.0027 17.8 0.1 0.0077 16.3 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 KII88702.1 - 0.0049 16.1 0.0 0.094 11.9 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KII88702.1 - 0.0052 16.0 0.3 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 KII88702.1 - 0.0063 16.0 5.3 0.12 11.7 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KII88702.1 - 0.007 15.8 0.3 0.27 10.7 0.0 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein Milton PF12448.8 KII88702.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Kinesin associated protein Img2 PF05046.14 KII88704.1 - 2e-21 76.1 0.0 2.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.17 KII88705.1 - 3.5e-54 184.1 0.0 5.6e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KII88705.1 - 5.8e-16 59.3 0.0 1.5e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KII88705.1 - 1.3e-15 56.8 0.0 3.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KII88705.1 - 1.1e-06 28.9 0.0 0.00039 20.7 0.0 3.0 2 0 0 2 2 2 2 Argonaute linker 2 domain ArgoMid PF16487.5 KII88705.1 - 0.00012 22.2 0.1 0.00034 20.8 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Ras PF00071.22 KII88706.1 - 3.4e-65 218.6 1.3 4e-65 218.4 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII88706.1 - 1.4e-36 125.4 0.1 2.2e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII88706.1 - 3.3e-17 62.5 0.3 3.9e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KII88706.1 - 1.2e-07 31.8 1.3 0.0012 18.8 0.4 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KII88706.1 - 3.9e-06 26.5 0.5 1.1e-05 25.1 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KII88706.1 - 1.1e-05 24.9 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KII88706.1 - 1.1e-05 24.9 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KII88706.1 - 2.9e-05 24.1 0.1 4.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KII88706.1 - 0.0059 17.0 0.1 0.52 10.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KII88706.1 - 0.0061 16.1 0.2 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KII88706.1 - 0.0067 16.8 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 KII88706.1 - 0.01 15.4 0.1 0.049 13.2 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.6 KII88706.1 - 0.037 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KII88706.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII88706.1 - 0.044 14.0 0.0 0.092 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KII88706.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KII88706.1 - 0.074 13.6 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KII88706.1 - 0.08 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Asp PF00026.23 KII88707.1 - 3e-30 105.7 0.0 1.4e-29 103.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII88707.1 - 0.03 14.5 0.2 0.062 13.5 0.2 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal zinc_ribbon_15 PF17032.5 KII88708.1 - 1.7e-05 25.4 0.1 2.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 zinc-ribbon family Vps36-NZF-N PF16988.5 KII88708.1 - 0.049 13.0 0.6 0.049 13.0 0.6 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3716 PF12511.8 KII88708.1 - 0.056 13.5 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.7 KII88708.1 - 0.092 12.7 1.2 0.3 11.1 1.2 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain efb-c PF12199.8 KII88709.1 - 0.16 12.1 0.2 0.25 11.5 0.2 1.2 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal Cyclin_N PF00134.23 KII88710.1 - 3.4e-08 33.3 0.0 9.7e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KII88710.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain Got1 PF04178.12 KII88711.1 - 1.1e-30 106.3 17.1 1.4e-30 106.0 17.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF5090 PF17009.5 KII88711.1 - 4.4 7.2 13.3 8.5 6.3 8.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) CHIP_TPR_N PF18391.1 KII88712.1 - 0.58 11.0 3.2 1.7 9.5 2.4 2.1 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain LigB PF02900.18 KII88713.1 - 1.4e-38 132.6 0.0 1.5e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.25 KII88714.1 - 7.8e-65 218.8 0.0 1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88714.1 - 2.7e-29 102.2 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII88714.1 - 0.00085 18.7 0.0 0.0019 17.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Brix PF04427.18 KII88715.1 - 4.1e-40 138.0 0.0 5.6e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain Drc1-Sld2 PF11719.8 KII88715.1 - 0.085 12.4 11.8 0.17 11.4 11.8 1.5 1 0 0 1 1 1 0 DNA replication and checkpoint protein PPL5 PF18168.1 KII88715.1 - 0.61 9.3 3.1 1.1 8.5 3.1 1.4 1 0 0 1 1 1 0 Prim-pol family 5 TFIIA PF03153.13 KII88715.1 - 1.7 8.6 15.1 2.2 8.2 15.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 KII88715.1 - 2.1 8.8 25.9 4.2 7.8 25.9 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 KII88715.1 - 6.7 6.0 27.1 10 5.4 27.1 1.2 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 KII88715.1 - 7.2 5.5 19.1 9.8 5.1 19.1 1.1 1 0 0 1 1 1 0 Paf1 Cyto_heme_lyase PF01265.17 KII88716.1 - 1.2e-43 149.8 7.8 8.5e-42 143.7 7.8 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase MAT1 PF06391.13 KII88717.1 - 1.2e-59 201.6 11.3 1.5e-59 201.3 11.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KII88717.1 - 9.5e-22 76.6 7.7 1.5e-21 76.0 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII88717.1 - 2e-05 24.4 6.9 3.7e-05 23.5 6.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII88717.1 - 5.5e-05 23.4 7.0 8.8e-05 22.8 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII88717.1 - 6.6e-05 22.7 6.1 0.00014 21.7 6.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII88717.1 - 0.00011 22.1 8.2 0.00044 20.2 8.5 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII88717.1 - 0.00055 19.7 8.8 0.0013 18.5 8.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KII88717.1 - 0.0078 16.5 2.8 0.015 15.6 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KII88717.1 - 0.016 15.0 9.4 0.28 11.1 9.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KII88717.1 - 0.027 14.5 3.0 0.043 13.9 1.6 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 KII88717.1 - 0.29 11.0 8.4 3 7.7 9.0 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KII88717.1 - 0.41 10.7 1.8 0.75 9.9 1.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KII88717.1 - 1.1 9.5 6.5 3.2 8.0 6.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3797 PF12677.7 KII88717.1 - 2.2 8.2 6.9 0.099 12.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CDC45 PF02724.14 KII88717.1 - 4.9 5.3 10.9 6.4 4.9 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YdjO PF14169.6 KII88717.1 - 9.1 6.1 6.8 23 4.8 0.1 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO Peptidase_C78 PF07910.13 KII88718.1 - 1.7e-40 138.7 0.0 2.9e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Proteasome PF00227.26 KII88719.1 - 7.1e-60 201.7 0.0 9.8e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII88719.1 - 2.4e-14 52.7 0.3 1.1e-13 50.5 0.1 2.3 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SRP-alpha_N PF04086.13 KII88720.1 - 1.5e-50 172.8 8.2 2.8e-49 168.6 8.2 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KII88720.1 - 3.1e-46 157.5 0.2 1.7e-45 155.1 0.2 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KII88720.1 - 5.3e-08 33.0 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KII88720.1 - 1.6e-05 24.0 0.1 4.6e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KII88720.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KII88720.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KII88720.1 - 0.018 14.2 0.1 1.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_24 PF13479.6 KII88720.1 - 0.028 14.2 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KII88720.1 - 0.034 14.0 0.1 0.16 11.9 0.1 2.1 1 1 0 1 1 1 0 NTPase Fer4_NifH PF00142.18 KII88720.1 - 0.037 13.5 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 KII88720.1 - 0.052 13.5 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KII88720.1 - 0.17 12.0 0.6 1.7 8.8 0.6 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 KII88721.1 - 8.9e-19 67.5 11.3 1.1e-09 38.7 0.3 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KII88721.1 - 0.00038 19.3 0.3 1.1 7.9 0.0 3.7 3 1 2 5 5 5 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KII88721.1 - 0.012 15.9 0.1 2.4 8.5 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII88721.1 - 0.49 9.0 2.6 5.5 5.5 0.6 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF3445 PF11927.8 KII88722.1 - 1.7e-72 243.7 0.0 2.2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ApoO PF09769.9 KII88722.1 - 0.018 15.0 0.1 0.032 14.2 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O NMO PF03060.15 KII88723.1 - 3.7e-55 187.6 0.6 6e-55 186.9 0.6 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KII88723.1 - 1e-09 37.9 0.7 2e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KII88723.1 - 0.0022 17.1 4.2 0.0034 16.4 4.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 KII88723.1 - 0.066 12.4 0.0 0.18 11.0 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like TPR_14 PF13428.6 KII88726.1 - 2e-07 31.3 22.7 12 7.1 0.0 11.8 12 3 3 15 15 15 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII88726.1 - 7.2e-07 28.9 11.5 0.066 13.3 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII88726.1 - 9.7e-07 29.2 2.8 0.93 10.0 0.1 5.4 4 1 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 KII88726.1 - 1.2e-05 25.5 9.3 0.00061 19.9 0.1 5.2 4 1 2 6 6 6 1 Suppressor of forked protein (Suf) TPR_12 PF13424.6 KII88726.1 - 0.00074 19.8 4.1 2.2 8.6 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KII88726.1 - 0.00075 18.7 5.3 1.2 8.1 0.1 5.0 3 2 2 5 5 5 1 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KII88726.1 - 0.0058 16.6 13.0 5.7 6.9 0.2 6.1 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KII88726.1 - 0.023 14.9 11.7 52 4.4 0.0 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat HAT PF02184.16 KII88726.1 - 4.4 7.4 12.3 2.8 8.0 0.1 5.5 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_1 PF00515.28 KII88726.1 - 7.4 6.6 7.4 62 3.7 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.22 KII88727.1 - 2.9e-40 134.9 18.0 8.1e-11 41.3 1.2 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat HAGH_C PF16123.5 KII88728.1 - 3.2e-19 69.2 0.0 5.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KII88728.1 - 6.5e-07 29.6 3.2 3.4e-05 23.9 3.2 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Phage_r1t_holin PF16945.5 KII88728.1 - 0.033 14.4 0.4 0.07 13.3 0.4 1.5 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Lactamase_B_2 PF12706.7 KII88728.1 - 0.045 13.3 0.2 0.13 11.8 0.2 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Phage_holin_3_6 PF07332.11 KII88729.1 - 0.061 13.4 0.4 0.094 12.8 0.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PhoR PF11808.8 KII88729.1 - 0.17 12.3 1.7 0.91 10.0 0.3 2.2 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Insulin_TMD PF17870.1 KII88729.1 - 0.22 11.6 0.0 0.36 10.9 0.0 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Tad PF13400.6 KII88729.1 - 0.26 11.6 2.5 0.38 11.1 2.5 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Gram_pos_anchor PF00746.21 KII88729.1 - 1.7 8.6 3.9 4.2 7.4 3.9 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Sec7 PF01369.20 KII88730.1 - 1e-66 224.1 0.0 1.7e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KII88730.1 - 3.1e-19 69.4 0.0 4e-18 65.8 0.0 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KII88730.1 - 0.0057 16.5 2.1 0.91 9.4 0.1 4.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Cytochrom_B561 PF03188.16 KII88731.1 - 2.5e-11 43.9 7.3 5.2e-11 42.8 6.7 1.8 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 NYN PF01936.18 KII88733.1 - 4.2e-15 56.5 0.1 7.6e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 NYN domain adh_short_C2 PF13561.6 KII88734.1 - 1e-51 175.8 0.1 1.4e-51 175.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII88734.1 - 1.3e-35 122.6 0.1 2e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII88734.1 - 2e-11 44.1 0.1 3.1e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Glu_dehyd_C PF16912.5 KII88734.1 - 0.032 13.7 0.1 0.25 10.8 0.1 2.1 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 KII88734.1 - 0.054 12.7 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2358 PF10184.9 KII88735.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) WD40 PF00400.32 KII88736.1 - 1.7e-28 98.3 12.8 2.5e-09 37.6 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88736.1 - 9.9e-08 32.2 0.0 0.0081 16.4 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII88736.1 - 0.00044 19.3 0.0 0.036 13.0 0.0 3.2 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Sulfate_transp PF00916.20 KII88737.1 - 1.1e-114 383.2 19.9 1.3e-114 382.9 19.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KII88737.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KII88737.1 - 0.0012 19.2 16.9 0.0064 16.9 3.1 2.7 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KII88737.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 STAS domain Claudin_3 PF06653.11 KII88737.1 - 0.023 14.7 2.0 0.09 12.7 2.0 2.0 1 0 0 1 1 1 0 Tight junction protein, Claudin-like F-box-like PF12937.7 KII88738.1 - 0.0022 17.9 0.1 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like Pkinase_Tyr PF07714.17 KII88740.1 - 2.5e-46 158.0 0.0 4.8e-28 98.2 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KII88740.1 - 1.7e-37 129.3 0.0 1.1e-36 126.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII88740.1 - 0.00089 19.2 0.0 0.003 17.5 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII88740.1 - 0.014 15.0 0.0 0.073 12.7 0.0 1.9 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 KII88740.1 - 0.029 13.7 0.0 1.3 8.3 0.0 2.4 1 1 0 1 1 1 0 Kinase-like PIN_4 PF13638.6 KII88741.1 - 1.1e-21 77.4 0.2 2.4e-21 76.4 0.2 1.6 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 KII88741.1 - 2.6e-09 37.0 0.0 5.9e-08 32.5 0.0 2.5 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Pex26 PF07163.12 KII88741.1 - 0.034 13.4 1.8 1.4 8.1 0.0 3.0 2 1 1 3 3 3 0 Pex26 protein CDH-cyt PF16010.5 KII88742.1 - 9e-09 35.3 0.1 3.5e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KII88742.1 - 2.9e-08 34.0 6.7 4.4e-08 33.4 6.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KII88742.1 - 4.6e-05 23.6 0.0 8.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF1461 PF07314.11 KII88742.1 - 0.13 12.1 0.4 0.34 10.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) DUF4079 PF13301.6 KII88742.1 - 0.21 11.7 8.9 0.25 11.5 4.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) NDK PF00334.19 KII88743.1 - 3.2e-55 185.9 0.0 3.6e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.16 KII88744.1 - 2.1e-38 130.3 2.0 2.5e-38 130.1 2.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.21 KII88745.1 - 8.1e-146 485.2 0.1 1.1e-145 484.8 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KII88745.1 - 5.8e-42 143.4 0.0 2e-41 141.6 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KII88745.1 - 4.8e-14 52.3 0.0 1.3e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KII88745.1 - 4.4e-05 22.8 0.1 7.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KII88745.1 - 0.00025 20.1 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Cmc1 PF08583.10 KII88746.1 - 9.5e-14 51.2 1.9 1.2e-13 50.9 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KII88746.1 - 0.026 14.7 3.2 0.45 10.7 0.3 2.2 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 KII88746.1 - 0.35 11.3 3.5 0.7 10.3 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) MFS_1 PF07690.16 KII88748.1 - 4.4e-29 101.5 63.5 9.2e-15 54.4 36.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 KII88749.1 - 5.9e-50 170.3 0.0 7.5e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.15 KII88749.1 - 0.0086 16.0 0.4 0.023 14.6 0.4 1.6 1 1 0 1 1 1 1 YjeF-related protein N-terminus AlaDh_PNT_C PF01262.21 KII88749.1 - 0.075 12.3 0.1 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 KII88750.1 - 7.1e-59 199.6 0.0 8.8e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TP_methylase PF00590.20 KII88750.1 - 0.016 15.2 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases AlaDh_PNT_C PF01262.21 KII88750.1 - 0.082 12.2 0.1 0.17 11.1 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Hydrolase PF00702.26 KII88750.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pet100 PF09803.9 KII88751.1 - 1.7e-26 92.5 0.1 2.4e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Pet100 Pyridoxal_deC PF00282.19 KII88753.1 - 3.4e-59 200.5 0.0 4.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KII88753.1 - 1.7e-05 24.0 0.0 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KII88753.1 - 0.027 13.2 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Rep_fac_C PF08542.11 KII88753.1 - 0.11 12.9 0.3 13 6.3 0.0 3.2 3 0 0 3 3 3 0 Replication factor C C-terminal domain Copper-bind PF00127.20 KII88755.1 - 0.00027 21.3 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DEC-1_N PF04625.13 KII88755.1 - 9.3 5.1 6.5 12 4.8 6.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Hid1 PF12722.7 KII88756.1 - 3.6e-185 617.5 0.0 4.4e-185 617.2 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KII88756.1 - 3.7e-94 316.4 0.0 4.8e-94 316.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MFS_1 PF07690.16 KII88757.1 - 1.3e-23 83.5 74.7 1.8e-20 73.2 46.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Saf_2TM PF18303.1 KII88757.1 - 0.088 12.4 1.1 0.77 9.3 0.4 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain F-box-like PF12937.7 KII88758.1 - 1.1e-08 34.8 1.9 3.9e-08 33.1 1.9 2.0 1 0 0 1 1 1 1 F-box-like CEP63 PF17045.5 KII88758.1 - 0.0097 15.8 0.8 0.018 15.0 0.8 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa DUF4349 PF14257.6 KII88758.1 - 0.061 12.8 1.5 0.1 12.1 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DivIC PF04977.15 KII88758.1 - 0.082 12.7 1.2 0.16 11.7 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Proteasom_PSMB PF10508.9 KII88758.1 - 0.24 9.9 0.0 0.43 9.0 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Rad51 PF08423.11 KII88759.1 - 1.6e-32 112.8 0.0 2.6e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 KII88759.1 - 0.00025 20.5 0.1 0.0011 18.3 0.1 1.8 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 KII88759.1 - 0.00088 18.8 0.1 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KII88759.1 - 0.009 15.6 0.0 0.5 9.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KII88759.1 - 0.044 13.1 0.3 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 KaiC DUF4332 PF14229.6 KII88759.1 - 0.12 12.6 0.0 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Med3 PF11593.8 KII88759.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Jagunal PF07086.12 KII88760.1 - 6.2 6.8 9.5 1.9 8.6 3.4 2.1 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis MFS_1 PF07690.16 KII88761.1 - 1.1e-39 136.3 37.0 1.1e-39 136.3 37.0 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 KII88761.1 - 0.00064 18.3 1.7 0.00098 17.7 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KII88761.1 - 0.0027 17.1 7.1 0.0027 17.1 7.1 2.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Glt_symporter PF03616.14 KII88761.1 - 0.043 12.5 2.3 0.079 11.6 2.3 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter MFS_1 PF07690.16 KII88762.1 - 9e-38 130.1 36.8 9e-38 130.1 36.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII88762.1 - 0.00094 18.6 8.2 0.00094 18.6 8.2 3.0 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Glt_symporter PF03616.14 KII88762.1 - 0.21 10.3 4.3 0.42 9.2 4.3 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter Lactamase_B_2 PF12706.7 KII88763.1 - 4.9e-09 36.0 0.0 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KII88763.1 - 4.5e-06 26.8 0.0 1.6e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KII88763.1 - 0.0077 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II DUF959 PF06121.14 KII88763.1 - 0.063 13.5 0.3 3.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF959) Tox-URI2 PF15653.6 KII88764.1 - 0.0033 17.6 0.1 0.0056 16.9 0.1 1.2 1 0 0 1 1 1 1 URI fold toxin 2 Glyco_hydro_63 PF03200.16 KII88765.1 - 2.7e-160 534.4 0.0 3e-159 530.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KII88765.1 - 2.5e-80 269.8 0.0 3.2e-79 266.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KII88765.1 - 0.0058 15.5 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Trehalase ARL17 PF15840.5 KII88765.1 - 0.055 13.8 1.0 0.55 10.6 0.2 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor-like protein 17 GDE_C PF06202.14 KII88765.1 - 0.08 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Band_7 PF01145.25 KII88766.1 - 1e-05 25.6 0.0 1e-05 25.6 0.0 3.4 3 1 0 3 3 3 1 SPFH domain / Band 7 family CRPA PF05745.11 KII88767.1 - 0.21 11.6 4.4 0.25 11.4 3.7 1.4 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) PMP1_2 PF08114.11 KII88767.1 - 0.24 11.2 3.2 4.5 7.1 0.2 2.9 2 0 0 2 2 2 0 ATPase proteolipid family DUF2569 PF10754.9 KII88767.1 - 0.28 11.6 6.6 0.22 12.0 5.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF4386 PF14329.6 KII88767.1 - 0.28 11.0 6.9 0.46 10.3 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF1761 PF08570.10 KII88767.1 - 0.43 10.8 6.1 21 5.4 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) PAP2_C PF14360.6 KII88767.1 - 0.7 10.5 9.7 0.13 12.8 5.8 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Bax1-I PF01027.20 KII88767.1 - 2.2 8.1 12.8 0.42 10.4 7.7 2.0 1 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Retrotran_gag_2 PF14223.6 KII88772.1 - 9.3e-16 57.7 0.0 1e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Joubert PF15392.6 KII88772.1 - 0.092 12.5 0.5 0.1 12.3 0.5 1.0 1 0 0 1 1 1 0 Joubert syndrome-associated Atg8 PF02991.16 KII88773.1 - 6.2e-52 174.1 0.2 7.3e-52 173.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KII88773.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.17 KII88773.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain ubiquitin PF00240.23 KII88774.1 - 7.3e-21 73.7 0.0 3e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KII88774.1 - 3.7e-09 36.3 0.0 8.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C3HC4_3 PF13920.6 KII88774.1 - 0.0023 17.7 8.1 0.0038 17.0 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TDA11 PF17084.5 KII88774.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Prok-RING_4 PF14447.6 KII88774.1 - 0.029 14.2 7.7 0.052 13.4 7.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KII88774.1 - 0.049 13.6 10.3 0.087 12.8 10.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Ubiquitin_2 PF14560.6 KII88774.1 - 0.092 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain zf-C3HC4 PF00097.25 KII88774.1 - 0.4 10.6 7.0 0.86 9.5 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII88774.1 - 2.9 7.8 9.6 5.8 6.9 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII88774.1 - 9.7 6.6 9.6 18 5.7 9.6 1.5 1 0 0 1 1 1 0 Ring finger domain Pkinase PF00069.25 KII88777.1 - 5.7e-63 212.7 0.0 6.8e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88777.1 - 1.4e-24 86.8 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII88777.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII88777.1 - 0.0014 18.6 0.1 0.058 13.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII88777.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KII88777.1 - 0.096 12.3 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KII88777.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KII88778.1 - 4.5e-46 153.9 20.4 2.1e-06 28.4 0.1 8.9 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KII88778.1 - 2.6e-12 46.4 0.0 5.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII88778.1 - 4.7e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KII88778.1 - 6.8e-11 41.5 4.1 0.016 13.9 0.5 6.1 4 1 1 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII88778.1 - 1.1e-05 25.6 0.3 3.5 8.0 0.1 5.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KII88778.1 - 4.5e-05 23.3 0.4 0.00049 20.0 0.0 2.8 3 0 0 3 3 3 1 F-box BBS2_Mid PF14783.6 KII88778.1 - 0.00018 21.5 0.1 15 5.7 0.0 4.8 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Pkinase_Tyr PF07714.17 KII88779.1 - 2.9e-44 151.3 0.0 5.2e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII88779.1 - 7.2e-38 130.5 0.0 1.5e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 KII88779.1 - 2.3e-26 93.1 0.8 2.3e-26 93.1 0.8 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KII88779.1 - 2.8e-11 43.6 0.2 7.6e-11 42.2 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Kinase-like PF14531.6 KII88779.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KII88779.1 - 0.14 12.1 1.2 0.27 11.1 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.7 KII88780.1 - 1.6e-07 31.1 1.5 6e-07 29.2 1.5 2.1 1 0 0 1 1 1 1 F-box-like NPV_P10 PF05531.12 KII88780.1 - 0.009 16.5 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 KII88780.1 - 0.011 16.3 0.4 0.024 15.2 0.4 1.6 1 0 0 1 1 1 0 SlyX RasGAP_C PF03836.15 KII88780.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus DUF2520 PF10728.9 KII88780.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) LRR_8 PF13855.6 KII88780.1 - 0.29 10.9 1.9 38 4.1 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat BRD4_CDT PF17105.5 KII88781.1 - 0.46 10.1 5.7 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 COQ7 PF03232.13 KII88783.1 - 6.8e-68 227.8 0.0 7.8e-68 227.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.12 KII88784.1 - 2.7e-05 24.1 0.0 3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.23 KII88785.1 - 1.3e-13 50.6 1.8 2.7e-13 49.6 1.8 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 KII88785.1 - 4.6e-12 45.6 0.1 5.5e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 KII88785.1 - 2.1e-05 24.5 2.1 5.9e-05 23.1 1.5 2.1 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 KII88785.1 - 0.012 15.2 0.8 0.023 14.3 0.8 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 KII88785.1 - 0.032 14.5 0.7 0.065 13.6 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PBP PF01161.20 KII88786.1 - 4.2e-10 40.1 0.0 6.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4644 PF15486.6 KII88786.1 - 0.39 10.4 3.9 0.37 10.5 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) PAP2 PF01569.21 KII88787.1 - 4.2e-26 91.3 2.7 4.2e-26 91.3 2.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF2085 PF09858.9 KII88787.1 - 0.32 11.5 5.2 0.46 11.0 1.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF2530 PF10745.9 KII88787.1 - 1 9.7 7.3 0.33 11.2 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) LRR19-TM PF15176.6 KII88788.1 - 0.041 13.9 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Amnionless PF14828.6 KII88788.1 - 0.049 12.5 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless FH2 PF02181.23 KII88789.1 - 5.3e-75 252.9 6.1 5.3e-75 252.9 6.1 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KII88789.1 - 5.8e-38 130.3 0.2 5.8e-38 130.3 0.2 2.9 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KII88789.1 - 9.3e-36 123.3 0.4 9.3e-36 123.3 0.4 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain WXG100 PF06013.12 KII88789.1 - 0.017 15.4 2.7 0.57 10.4 0.0 3.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG COG5 PF10392.9 KII88789.1 - 0.085 13.0 6.7 12 6.1 0.0 3.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 EPL1 PF10513.9 KII88789.1 - 6.2 7.2 10.8 4 7.8 1.5 3.5 3 0 0 3 3 3 0 Enhancer of polycomb-like COG4 PF08318.12 KII88790.1 - 1.1e-94 317.3 0.0 2.1e-94 316.4 0.0 1.5 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 KII88790.1 - 0.0059 15.6 0.0 0.033 13.1 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family JIP_LZII PF16471.5 KII88790.1 - 0.026 14.7 0.3 0.099 12.8 0.3 2.1 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF2379 PF09543.10 KII88790.1 - 0.47 10.6 3.6 0.75 10.0 2.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2379) DIL PF01843.19 KII88790.1 - 0.94 9.8 3.0 3.8 7.8 0.0 3.1 4 0 0 4 4 4 0 DIL domain Snf7 PF03357.21 KII88791.1 - 7.4e-39 133.1 18.5 7.4e-39 133.1 18.5 1.7 2 0 0 2 2 2 1 Snf7 Exonuc_VII_L PF02601.15 KII88791.1 - 0.2 11.2 3.9 0.25 10.9 3.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 KII88791.1 - 0.56 9.5 4.9 0.81 9.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-AN1 PF01428.16 KII88792.1 - 2.2e-18 66.1 21.1 2.7e-09 37.0 8.0 2.8 2 1 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KII88792.1 - 0.0015 18.8 11.6 0.018 15.4 2.7 2.7 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 KII88792.1 - 0.02 15.1 2.6 0.02 15.1 2.6 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Myosin_head PF00063.21 KII88793.1 - 1.2e-258 859.9 0.0 3.3e-257 855.1 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KII88793.1 - 1.5e-26 92.7 7.7 3.6e-26 91.5 1.8 3.7 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 KII88793.1 - 9e-09 34.4 44.2 0.011 15.4 1.5 7.2 7 0 0 7 7 7 5 IQ calmodulin-binding motif DUF812 PF05667.11 KII88793.1 - 0.0056 15.6 16.8 0.0098 14.8 16.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Myosin_N PF02736.19 KII88793.1 - 0.0076 16.1 0.3 0.017 15.0 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KII88793.1 - 0.017 15.4 0.9 0.16 12.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TMF_DNA_bd PF12329.8 KII88793.1 - 0.065 13.2 21.8 0.021 14.8 6.0 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA_16 PF13191.6 KII88793.1 - 0.33 11.3 0.0 0.33 11.3 0.0 3.8 2 1 0 2 2 1 0 AAA ATPase domain HMMR_C PF15908.5 KII88793.1 - 1.7 8.9 17.5 23 5.2 16.2 2.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal CENP-F_leu_zip PF10473.9 KII88793.1 - 2.7 8.0 24.7 0.093 12.8 13.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 KII88793.1 - 2.9 6.4 11.0 5.2 5.5 11.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_MLP1_2 PF07926.12 KII88793.1 - 7.9 6.6 33.3 0.2 11.7 8.1 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FUSC_2 PF13515.6 KII88794.1 - 9.7e-13 48.3 12.3 9.7e-13 48.3 12.3 3.1 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KII88794.1 - 4.9e-10 39.0 15.8 7.6e-05 21.9 2.9 3.3 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KII88794.1 - 2.7e-06 27.4 2.0 2.8e-06 27.3 0.4 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KII88794.1 - 7.7e-06 25.0 23.1 9.3e-06 24.7 7.6 3.5 4 0 0 4 4 4 2 Aluminium activated malate transporter Uds1 PF15456.6 KII88794.1 - 0.018 15.2 6.6 0.073 13.2 0.8 3.4 2 1 0 2 2 2 0 Up-regulated During Septation Fungal_trans PF04082.18 KII88798.1 - 3.6e-08 32.8 0.3 3.6e-08 32.8 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII88798.1 - 2.7e-05 24.2 12.0 6.4e-05 23.0 12.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RRN7 PF11781.8 KII88798.1 - 0.29 10.8 4.1 0.59 9.9 4.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 WD40 PF00400.32 KII88799.1 - 0.053 14.4 0.1 0.053 14.4 0.1 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat ADK PF00406.22 KII88801.1 - 2.7e-45 154.1 1.1 1.6e-43 148.4 1.1 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KII88801.1 - 2.8e-31 108.8 0.1 4.5e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KII88801.1 - 7.4e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII88801.1 - 2.8e-05 24.3 0.3 0.00019 21.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KII88801.1 - 0.00054 19.7 0.7 0.29 10.8 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KII88801.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 KII88801.1 - 0.13 11.6 0.2 1.3 8.3 0.1 2.4 2 1 0 2 2 2 0 Zeta toxin DAGK_cat PF00781.24 KII88802.1 - 6.8e-15 54.8 0.2 1.5e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain CN_hydrolase PF00795.22 KII88803.1 - 4.6e-57 193.3 0.0 5.1e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ_C PF01556.18 KII88804.1 - 1.6e-39 135.3 0.4 2.2e-39 134.9 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KII88804.1 - 2.4e-21 75.6 1.6 4e-21 74.9 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KII88804.1 - 6.5e-17 61.7 18.8 1.1e-16 61.0 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KII88804.1 - 0.0015 18.5 15.9 0.0044 16.9 2.7 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KII88804.1 - 0.55 10.3 6.8 6 7.0 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 KII88804.1 - 3.3 7.7 11.5 6.9 6.7 2.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5351 PF17302.2 KII88804.1 - 8 6.8 16.8 11 6.3 0.4 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) DUF2340 PF10209.9 KII88805.1 - 3.5e-51 172.7 0.5 4.1e-51 172.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KII88805.1 - 0.0026 18.1 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Glyco_hydro_3_C PF01915.22 KII88806.1 - 5.5e-61 206.1 0.0 9e-61 205.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII88806.1 - 3.9e-47 161.2 0.0 6.2e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII88806.1 - 1.8e-21 76.0 0.0 3.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KII88806.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.9 KII88806.1 - 0.0083 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein GLEYA PF10528.9 KII88806.1 - 0.014 15.8 0.1 0.034 14.6 0.1 1.6 1 0 0 1 1 1 0 GLEYA domain adh_short PF00106.25 KII88807.1 - 1.2e-40 139.1 1.7 1.6e-40 138.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII88807.1 - 5.5e-23 81.7 1.1 7.2e-23 81.4 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88807.1 - 8e-08 32.4 0.6 1.2e-07 31.9 0.6 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KII88807.1 - 0.013 15.5 0.2 0.026 14.5 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KII88807.1 - 0.025 14.4 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KII88807.1 - 0.037 14.3 0.1 0.067 13.5 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KII88807.1 - 0.084 12.0 0.4 0.12 11.5 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KII88807.1 - 0.092 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Myb_Cef PF11831.8 KII88811.1 - 2e-63 214.2 0.3 2e-63 214.2 0.3 3.9 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KII88811.1 - 2.2e-20 72.6 3.6 1.9e-09 37.5 0.5 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII88811.1 - 1.2e-17 63.8 4.6 1.1e-11 44.8 1.6 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Nup188_C PF18378.1 KII88811.1 - 0.37 9.6 3.1 0.62 8.8 3.1 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain DUF1690 PF07956.11 KII88813.1 - 1.3e-38 132.5 3.0 1.8e-38 132.1 3.0 1.2 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 KII88813.1 - 0.00039 20.5 4.8 0.00054 20.0 4.8 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Metal_resist PF13801.6 KII88813.1 - 0.014 15.5 2.7 0.022 14.9 2.7 1.3 1 0 0 1 1 1 0 Heavy-metal resistance pPIWI_RE_X PF13111.6 KII88813.1 - 0.044 13.0 0.2 0.054 12.7 0.2 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain YojJ PF10372.9 KII88813.1 - 0.066 13.3 0.6 13 6.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus ALMT PF11744.8 KII88813.1 - 0.067 12.0 0.7 0.073 11.9 0.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DegS PF05384.11 KII88813.1 - 0.16 11.5 7.0 0.38 10.2 7.0 1.6 1 1 0 1 1 1 0 Sensor protein DegS APG6_N PF17675.1 KII88813.1 - 1.5 9.3 11.6 3.7 8.1 11.0 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region HA2 PF04408.23 KII88814.1 - 1e-15 57.9 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KII88814.1 - 7.9e-14 52.0 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KII88814.1 - 8.9e-12 45.2 0.0 2.1e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KII88814.1 - 3.9e-06 26.7 0.0 9.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII88814.1 - 5.4e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII88814.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII88814.1 - 0.0026 18.1 0.0 0.0086 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KII88814.1 - 0.0082 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KII88814.1 - 0.03 14.4 0.1 1.2 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KII88814.1 - 0.11 13.0 0.1 0.52 10.8 0.1 2.1 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KII88814.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KII88814.1 - 0.2 10.9 0.2 0.64 9.3 0.1 1.8 1 1 1 2 2 2 0 Zeta toxin DUF572 PF04502.13 KII88815.1 - 8.8e-82 275.4 6.2 1.1e-81 275.1 6.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 KII88815.1 - 0.029 14.3 0.4 0.048 13.6 0.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-FCS PF06467.14 KII88815.1 - 0.12 12.3 1.1 4 7.5 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Mis14 PF08641.12 KII88816.1 - 2e-07 31.4 5.1 4.5e-07 30.2 5.1 1.7 1 1 0 1 1 1 1 Kinetochore protein Mis14 like APP_E2 PF12925.7 KII88816.1 - 0.0097 15.6 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein Remorin_C PF03763.13 KII88816.1 - 0.043 13.7 1.0 8 6.4 0.1 2.4 2 0 0 2 2 2 0 Remorin, C-terminal region BAG PF02179.16 KII88816.1 - 0.068 13.6 0.5 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 BAG domain Thg1 PF04446.12 KII88816.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 tRNAHis guanylyltransferase V-ATPase_G_2 PF16999.5 KII88816.1 - 0.27 11.7 5.5 18 5.8 3.3 2.4 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Gar1 PF04410.14 KII88817.1 - 2.3e-37 128.2 0.0 2.8e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 KII88818.1 - 1.1e-62 210.3 0.0 3.8e-44 150.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII88818.1 - 2.5e-09 36.8 3.3 4.7e-06 26.3 0.1 3.4 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KII88818.1 - 2.1e-07 31.5 0.3 0.0081 16.6 0.0 4.0 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KII88818.1 - 3.2e-06 27.0 0.0 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KII88818.1 - 1.3e-05 25.2 0.2 0.03 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KII88818.1 - 0.00022 21.8 0.0 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 KII88818.1 - 0.00038 20.4 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KII88818.1 - 0.00038 20.7 0.4 0.027 14.8 0.1 3.1 2 1 1 3 3 3 1 AAA domain TsaE PF02367.17 KII88818.1 - 0.00042 20.3 0.0 0.15 12.1 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KII88818.1 - 0.0012 18.1 0.0 0.034 13.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 KII88818.1 - 0.0014 18.8 0.1 0.38 10.9 0.0 3.0 4 0 0 4 4 2 1 AAA domain Sigma54_activat PF00158.26 KII88818.1 - 0.0017 18.1 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KII88818.1 - 0.0017 18.1 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 KII88818.1 - 0.0021 17.7 0.3 0.013 15.1 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 KII88818.1 - 0.0023 17.9 0.0 0.71 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KII88818.1 - 0.0037 16.6 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_2 PF07724.14 KII88818.1 - 0.0059 16.7 0.0 0.022 14.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 KII88818.1 - 0.0071 16.7 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KII88818.1 - 0.0086 15.5 0.2 0.047 13.1 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KII88818.1 - 0.012 14.8 0.1 1.1 8.4 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KII88818.1 - 0.017 15.4 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KII88818.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KII88818.1 - 0.03 13.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 KII88818.1 - 0.038 13.8 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KII88818.1 - 0.047 13.5 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_24 PF13479.6 KII88818.1 - 0.055 13.2 0.6 0.21 11.3 0.1 2.2 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KII88818.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 KII88818.1 - 0.07 13.0 0.9 3.6 7.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain SKI PF01202.22 KII88818.1 - 0.21 11.7 0.1 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase PhoD PF09423.10 KII88819.1 - 5e-36 124.5 1.4 1.9e-35 122.5 1.4 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 KII88819.1 - 0.011 16.3 0.8 0.049 14.2 0.0 2.6 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain GalP_UDP_transf PF01087.22 KII88820.1 - 9e-60 202.2 0.0 1.5e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KII88820.1 - 5.1e-49 166.2 0.0 1.1e-48 165.2 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 KII88820.1 - 0.0049 17.3 0.0 0.0095 16.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KII88820.1 - 0.012 16.4 0.7 0.11 13.2 0.2 2.7 3 1 0 3 3 3 0 HIT domain DUF4921 PF16268.5 KII88820.1 - 0.02 13.8 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) NUDIX PF00293.28 KII88821.1 - 3.5e-16 59.4 0.4 1.8e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Phage_integrase PF00589.22 KII88827.1 - 0.00035 20.4 0.2 0.0052 16.6 0.0 2.7 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KII88827.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SopE_GEF PF07487.13 KII88827.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain DUF2510 PF10708.9 KII88827.1 - 0.71 9.7 3.1 37 4.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2510) DUF4219 PF13961.6 KII88834.1 - 3.8e-05 23.2 0.2 7.6e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 KII88834.1 - 0.0013 18.4 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII88834.1 - 0.0014 18.3 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4801 PF16059.5 KII88837.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) NHase_beta PF02211.15 KII88837.1 - 1.2 9.1 4.5 0.68 9.9 2.0 1.7 1 1 1 2 2 2 0 Nitrile hydratase beta subunit zf-CCHC PF00098.23 KII88838.1 - 3.3 8.0 6.0 0.79 9.9 2.2 2.0 2 0 0 2 2 2 0 Zinc knuckle Integrase_H2C2 PF17921.1 KII88840.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain AraC_binding PF02311.19 KII88841.1 - 0.019 14.9 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 KII88841.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Chromo PF00385.24 KII88842.1 - 4.4e-10 39.3 0.0 4.8e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TMF_DNA_bd PF12329.8 KII88844.1 - 0.0013 18.7 2.0 0.0013 18.7 2.0 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 KII88844.1 - 0.0036 17.3 1.3 0.0055 16.7 1.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 KII88844.1 - 0.0046 17.0 2.8 0.0046 17.0 2.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor GAS PF13851.6 KII88844.1 - 0.0053 16.1 0.6 0.0069 15.8 0.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 KII88844.1 - 0.0076 14.5 0.6 0.0089 14.3 0.6 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA BRE1 PF08647.11 KII88844.1 - 0.0097 16.0 1.9 0.015 15.3 1.9 1.4 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase ZapB PF06005.12 KII88844.1 - 0.012 16.1 1.6 0.025 15.0 1.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 KII88844.1 - 0.02 15.3 1.5 0.061 13.7 1.5 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) CorA PF01544.18 KII88844.1 - 0.044 13.1 0.2 0.053 12.8 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cnn_1N PF07989.11 KII88844.1 - 0.044 13.9 2.1 0.069 13.3 2.1 1.5 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 KII88844.1 - 0.054 13.3 2.0 0.13 12.1 2.0 1.7 1 1 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.9 KII88844.1 - 0.057 13.4 2.3 0.089 12.7 2.3 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain SlyX PF04102.12 KII88844.1 - 0.062 13.9 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 SlyX Csm1_N PF18504.1 KII88844.1 - 0.075 13.4 2.7 0.18 12.1 2.7 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain Prefoldin_2 PF01920.20 KII88844.1 - 0.081 12.9 1.9 0.14 12.1 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF4407 PF14362.6 KII88844.1 - 0.16 11.3 0.7 0.18 11.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Noc2 PF03715.13 KII88844.1 - 0.19 11.0 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Noc2p family Atg14 PF10186.9 KII88844.1 - 0.26 10.3 5.7 0.45 9.6 5.7 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VCPO_N PF17897.1 KII88848.1 - 0.28 11.0 4.0 4.3 7.1 0.1 2.6 3 0 0 3 3 3 0 Vanadium chloroperoxidase N-terminal domain DUF924 PF06041.11 KII88849.1 - 0.045 13.9 2.0 0.055 13.6 0.7 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) Cauli_VI PF01693.16 KII88850.1 - 1.6e-19 69.9 0.2 1.3e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin MucBP_2 PF17965.1 KII88850.1 - 0.078 13.6 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Mucin binding domain Gpi1 PF05024.15 KII88851.1 - 7.9e-61 205.4 7.4 1.4e-60 204.6 7.4 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) TMEM190 PF15431.6 KII88851.1 - 0.063 13.4 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 190 Ras PF00071.22 KII88852.1 - 2.2e-53 180.2 0.0 2.6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII88852.1 - 3.6e-22 78.8 0.0 5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII88852.1 - 2.6e-06 27.0 0.0 7.6e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KII88852.1 - 0.011 15.6 0.0 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KII88852.1 - 0.027 13.8 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII88852.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PIG-X PF08320.12 KII88853.1 - 2.9e-36 125.4 0.0 3.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 Gemin7 PF11095.8 KII88853.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) 6PF2K PF01591.18 KII88854.1 - 8.9e-71 237.7 0.0 1.2e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KII88854.1 - 4.8e-37 127.5 0.0 8.6e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KII88854.1 - 7.3e-07 29.4 0.1 1.3e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KII88854.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rsa3 PF14615.6 KII88854.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Ribosome-assembly protein 3 KTI12 PF08433.10 KII88854.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_transf_8 PF01501.20 KII88855.1 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KII88855.1 - 0.041 13.9 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_24 PF18404.1 KII88855.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucosyltransferase 24 PNK3P PF08645.11 KII88856.1 - 3.6e-45 153.6 0.0 7.3e-44 149.3 0.0 2.1 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KII88856.1 - 7e-19 68.4 0.1 3.2e-16 59.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KII88856.1 - 2.5e-07 30.2 0.0 0.01 15.2 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin LNS2 PF08235.13 KII88856.1 - 3.6e-06 26.6 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hydrolase_6 PF13344.6 KII88856.1 - 4.8e-05 23.4 0.0 0.042 14.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.23 KII88856.1 - 0.00034 20.7 0.0 0.0007 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.10 KII88856.1 - 0.00058 19.4 4.4 0.086 12.3 4.4 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KII88856.1 - 0.026 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PITH PF06201.13 KII88857.1 - 1.8e-39 135.4 0.1 2.1e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 PITH domain Sel1 PF08238.12 KII88858.1 - 2.4e-47 158.3 24.3 1.3e-09 38.4 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat DUF4562 PF15123.6 KII88858.1 - 0.061 13.3 0.5 0.46 10.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) ANAPC3 PF12895.7 KII88858.1 - 1.2 9.4 11.3 0.61 10.3 1.7 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KII88858.1 - 9.8 7.3 17.3 1.1 10.2 1.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat JHD PF17811.1 KII88859.1 - 1.1e-10 42.0 0.0 2.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KII88859.1 - 1.7e-08 34.9 2.0 3e-07 30.9 2.0 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KII88859.1 - 2.1e-07 30.7 8.8 3.9e-07 29.9 8.8 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 KII88859.1 - 0.00013 21.8 3.7 0.00024 20.9 1.0 2.5 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.6 KII88859.1 - 0.0093 15.5 3.7 0.018 14.6 3.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KII88859.1 - 0.093 12.7 5.2 0.18 11.8 5.2 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-HC5HC2H PF13771.6 KII88859.1 - 0.23 11.8 2.7 0.45 10.8 2.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-CW PF07496.15 KII88859.1 - 0.56 10.3 7.6 1.7 8.7 7.6 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger PGK PF00162.19 KII88860.1 - 4.8e-146 486.5 0.0 5.4e-146 486.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Exop_C PF18559.1 KII88861.1 - 0.12 12.2 2.9 0.21 11.4 2.9 1.3 1 0 0 1 1 1 0 Galactose-binding domain-like SDA1 PF05285.12 KII88862.1 - 1.2e-85 288.1 41.8 3.2e-83 280.1 37.2 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KII88862.1 - 1.4e-24 86.2 0.0 3.6e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain CFEM PF05730.11 KII88863.1 - 1.2e-09 38.1 15.0 2.1e-09 37.4 15.0 1.3 1 0 0 1 1 1 1 CFEM domain DEAD PF00270.29 KII88864.1 - 1.7e-43 148.4 0.0 5.4e-43 146.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII88864.1 - 7.4e-27 93.9 0.0 6.1e-26 90.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII88864.1 - 7.6e-06 26.0 0.0 4e-05 23.7 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KII88864.1 - 0.018 14.4 6.4 0.31 10.4 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KII88866.1 - 1.7e-22 80.0 0.0 3.4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII88866.1 - 1.2e-21 77.1 0.0 6.7e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 KII88866.1 - 1.4e-12 47.4 0.0 5.6e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 KII88866.1 - 7.4e-12 45.8 6.7 1.7e-11 44.7 3.7 2.5 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 KII88866.1 - 2.7e-06 27.5 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peripla_BP_4 PF13407.6 KII88866.1 - 0.13 11.8 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein domain DHR10 PF18595.1 KII88867.1 - 6.3e-31 106.8 20.9 6.3e-31 106.8 20.9 4.2 3 1 1 4 4 4 2 Designed helical repeat protein 10 domain Nuf2 PF03800.14 KII88867.1 - 8.2e-29 100.5 0.1 3.6e-28 98.4 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family GAS PF13851.6 KII88867.1 - 0.001 18.4 43.2 0.026 13.9 14.1 3.8 3 1 1 4 4 4 3 Growth-arrest specific micro-tubule binding Syntaxin_2 PF14523.6 KII88867.1 - 0.012 15.9 8.6 0.012 15.9 8.6 3.4 1 1 2 3 3 3 0 Syntaxin-like protein DUF3450 PF11932.8 KII88867.1 - 0.015 14.6 32.3 0.066 12.5 10.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DXP_reductoisom PF02670.16 KII88867.1 - 4.6 8.0 8.5 15 6.3 0.3 2.8 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase APG6_N PF17675.1 KII88867.1 - 5.8 7.5 49.5 21 5.7 12.6 4.2 2 1 1 4 4 4 0 Apg6 coiled-coil region ZapB PF06005.12 KII88867.1 - 8 7.0 36.7 8.3 6.9 7.9 4.9 4 1 0 4 4 4 0 Cell division protein ZapB ING PF12998.7 KII88868.1 - 9e-12 45.5 0.0 7.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KII88868.1 - 2.1e-05 24.3 9.3 3.6e-05 23.6 9.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KII88868.1 - 0.042 14.1 1.2 0.088 13.1 1.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain HNF-1A_C PF04813.12 KII88868.1 - 3.9 8.3 11.1 0.31 11.8 2.4 3.1 3 1 1 4 4 4 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Pkinase_Tyr PF07714.17 KII88869.1 - 3.8e-33 114.9 0.0 1.8e-32 112.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII88869.1 - 8.3e-30 104.0 0.0 9.4e-29 100.6 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KII88869.1 - 0.014 14.8 0.4 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.18 KII88870.1 - 0.0042 17.2 18.2 0.0059 16.7 18.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KII88871.1 - 1e-48 166.0 0.4 2.3e-47 161.6 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88871.1 - 2.1e-15 56.7 0.2 2e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase ABC1 PF03109.16 KII88871.1 - 0.0078 16.4 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KII88871.1 - 0.0078 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII88871.1 - 0.049 13.2 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 RIO1 family PTPRCAP PF15713.5 KII88871.1 - 6.9 6.9 12.5 12 6.1 1.6 3.3 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated AAA PF00004.29 KII88872.1 - 3.8e-41 140.6 0.0 1.1e-40 139.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 KII88872.1 - 1.4e-40 138.8 0.0 2.7e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KII88872.1 - 3.5e-06 27.5 0.0 0.00056 20.4 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 KII88872.1 - 9.8e-06 25.3 0.1 2.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KII88872.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII88872.1 - 0.00038 20.7 0.0 0.011 15.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KII88872.1 - 0.00043 20.7 0.1 0.0043 17.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KII88872.1 - 0.001 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KII88872.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KII88872.1 - 0.0073 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KII88872.1 - 0.026 14.7 0.0 0.071 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KII88872.1 - 0.027 14.0 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KII88872.1 - 0.048 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain HATPase_c_3 PF13589.6 KII88872.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_3 PF07726.11 KII88872.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KII88872.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KII88872.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KII88872.1 - 0.13 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KII88872.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 KII88872.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 KII88873.1 - 7.1e-108 359.1 0.0 9.8e-108 358.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KII88873.1 - 1.4e-43 147.6 0.0 2.7e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KII88873.1 - 1.8e-14 54.0 4.1 4.9e-14 52.6 4.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Fasciclin PF02469.22 KII88874.1 - 1.1e-34 119.4 0.2 4e-13 49.7 0.0 4.3 3 1 0 3 3 3 3 Fasciclin domain IPPT PF01715.17 KII88875.1 - 5.1e-57 193.3 0.0 9.5e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KII88875.1 - 0.00029 21.4 0.2 0.034 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KII88875.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 KII88875.1 - 0.024 14.7 0.5 0.056 13.5 0.4 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KII88875.1 - 0.028 14.7 0.0 0.078 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII88875.1 - 0.037 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 KII88875.1 - 0.059 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.17 KII88875.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Ribosomal_L27A PF00828.19 KII88876.1 - 3.6e-33 114.9 0.0 5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3653 PF12375.8 KII88876.1 - 0.011 15.8 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Phage protein PRP38 PF03371.15 KII88877.1 - 2.7e-61 206.5 1.3 3.2e-61 206.2 1.3 1.1 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.6 KII88877.1 - 0.025 14.9 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats PRP38_assoc PF12871.7 KII88877.1 - 0.069 13.8 33.2 0.1 13.2 33.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MAP65_ASE1 PF03999.12 KII88877.1 - 0.36 9.5 10.0 0.39 9.4 8.7 1.6 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) PHD PF00628.29 KII88879.1 - 3.7e-16 58.8 16.1 5.8e-10 38.9 5.2 2.8 3 0 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 KII88879.1 - 0.0074 15.8 10.2 0.11 12.0 0.6 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 KII88879.1 - 0.0093 15.8 5.4 0.35 10.8 0.3 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KII88879.1 - 0.014 15.1 5.2 0.02 14.5 0.5 2.6 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 KII88879.1 - 0.12 12.6 3.0 0.16 12.3 1.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_3 PF13922.6 KII88879.1 - 1.9 8.9 5.1 4.3 7.8 0.1 2.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING-like PF08746.11 KII88879.1 - 5.2 7.5 9.3 5.7 7.3 0.5 2.6 2 0 0 2 2 2 0 RING-like domain PGM_PMM_I PF02878.16 KII88880.1 - 4.1e-38 130.2 0.1 8.6e-38 129.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KII88880.1 - 5.1e-20 71.8 0.2 1.8e-18 66.8 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KII88880.1 - 1.5e-19 70.5 0.0 3.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KII88880.1 - 4.5e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.9 KII88881.1 - 4.4e-76 256.6 0.0 8.2e-65 219.4 0.0 3.3 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor F-box-like PF12937.7 KII88882.1 - 1.6e-09 37.5 0.1 3.8e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KII88882.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain zf-trcl PF13451.6 KII88883.1 - 0.39 10.7 0.2 0.39 10.7 0.2 2.8 3 0 0 3 3 3 0 Probable zinc-ribbon domain ArfGap PF01412.18 KII88883.1 - 7.7 6.6 11.5 45 4.1 11.5 1.9 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf Gasdermin PF04598.12 KII88884.1 - 0.08 12.4 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain RNase_H PF00075.24 KII88887.1 - 0.00086 19.5 0.5 0.0016 18.6 0.2 1.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KII88888.1 - 7.3e-05 23.4 0.7 0.00014 22.5 0.7 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF484 PF04340.12 KII88889.1 - 0.00038 20.2 0.3 0.00062 19.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF484 F-box PF00646.33 KII88889.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.4 2 0 0 2 2 2 0 F-box domain Phostensin_N PF13916.6 KII88889.1 - 3.5 8.0 6.0 0.9 9.9 1.6 2.2 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal R3H PF01424.22 KII88890.1 - 2.2e-10 40.3 0.1 4.5e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KII88890.1 - 6.7e-08 32.2 0.0 1.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KII88892.1 - 2.3e-45 153.7 0.0 2.7e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII88892.1 - 0.00027 21.2 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KII88892.1 - 0.0089 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B EF-hand_4 PF12763.7 KII88893.1 - 1.1e-35 121.7 0.0 4.2e-14 52.4 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KII88893.1 - 3e-07 30.8 0.0 0.0069 16.8 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 KII88893.1 - 7.2e-05 22.6 0.0 0.00018 21.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 KII88893.1 - 0.0056 16.1 4.6 10 6.0 0.0 5.2 6 0 0 6 6 6 0 EF hand APG6_N PF17675.1 KII88893.1 - 0.026 15.0 33.6 0.18 12.3 13.2 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 KII88893.1 - 0.04 14.4 28.9 0.072 13.5 11.7 2.2 1 1 1 2 2 2 0 Fez1 EF-hand_8 PF13833.6 KII88893.1 - 0.093 12.6 0.2 9.2 6.2 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair ATG16 PF08614.11 KII88893.1 - 0.52 10.5 37.7 2.8 8.1 15.7 2.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 KII88893.1 - 1.1 9.0 25.7 14 5.5 6.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KII88893.1 - 1.1 8.1 33.5 1.7 7.4 23.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein CCDC144C PF14915.6 KII88893.1 - 1.3 8.1 23.8 2.5 7.1 23.8 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region ADIP PF11559.8 KII88893.1 - 1.7 8.8 22.9 2.7 8.1 8.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 KII88893.1 - 2.9 8.0 21.5 1.8 8.7 4.8 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.8 KII88893.1 - 3.1 5.2 27.9 5.4 4.4 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KII88893.1 - 4.3 6.7 29.0 2.5 7.5 16.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF812 PF05667.11 KII88893.1 - 5.4 5.8 23.6 9.3 5.0 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.19 KII88893.1 - 5.6 4.7 8.8 9.3 4.0 8.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 KII88893.1 - 7.2 6.7 15.4 1.4 9.0 1.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TaqI_C PF12950.7 KII88895.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain PDEase_II PF02112.15 KII88896.1 - 1.3e-43 149.5 0.0 3.5e-43 148.0 0.0 1.6 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KII88896.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.32 KII88898.1 - 9.7e-39 130.7 7.6 1.9e-07 31.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII88898.1 - 2.1e-11 43.9 0.6 0.16 12.3 0.0 5.8 2 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KII88898.1 - 0.0012 17.6 0.1 0.29 9.8 0.0 3.2 2 2 2 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 KII88898.1 - 0.0021 16.8 0.5 2.8 6.5 0.0 3.8 2 1 0 4 4 4 2 Nucleoporin Nup120/160 Striatin PF08232.12 KII88899.1 - 6.2e-37 127.6 2.7 6.2e-37 127.6 2.7 2.1 2 0 0 2 2 2 1 Striatin family TFIIA PF03153.13 KII88899.1 - 0.00058 20.0 27.7 0.00067 19.8 27.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CALCOCO1 PF07888.11 KII88899.1 - 0.0082 15.1 1.4 0.0082 15.1 1.4 2.0 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DDHD PF02862.17 KII88899.1 - 0.017 15.3 3.4 0.02 15.0 3.4 1.1 1 0 0 1 1 1 0 DDHD domain EPL1 PF10513.9 KII88899.1 - 0.024 15.0 6.2 0.026 14.9 6.2 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like KfrA_N PF11740.8 KII88899.1 - 0.039 14.6 16.0 0.33 11.7 10.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4852 PF16144.5 KII88899.1 - 0.046 13.8 0.1 0.046 13.8 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4852) SpoIIP PF07454.11 KII88899.1 - 0.16 11.4 6.2 0.17 11.3 6.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 KII88899.1 - 0.17 10.8 9.5 0.17 10.9 9.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 KII88899.1 - 0.17 11.6 5.3 0.19 11.5 5.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UPF0560 PF10577.9 KII88899.1 - 0.18 10.2 12.6 0.18 10.3 12.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4482 PF14818.6 KII88899.1 - 0.3 12.0 17.0 0.14 13.0 3.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) Presenilin PF01080.17 KII88899.1 - 0.32 9.7 7.4 0.31 9.8 7.4 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KII88899.1 - 0.59 10.2 5.1 0.62 10.1 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 KII88899.1 - 0.69 9.5 34.9 0.95 9.0 34.9 1.3 1 0 0 1 1 1 0 Spt20 family Exonuc_VII_L PF02601.15 KII88899.1 - 0.69 9.4 10.2 0.85 9.1 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 KII88899.1 - 0.71 10.4 9.9 13 6.3 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2722 PF10846.8 KII88899.1 - 0.85 8.5 26.2 1.2 8.0 26.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Het-C PF07217.11 KII88899.1 - 1.1 7.7 5.2 1.3 7.4 5.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TERB2 PF15101.6 KII88899.1 - 1.1 9.2 11.8 1.8 8.6 11.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 KII88899.1 - 1.2 7.3 23.2 1.2 7.4 23.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 KII88899.1 - 2.1 7.1 4.5 2.3 7.0 4.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ndc1_Nup PF09531.10 KII88899.1 - 2.2 6.9 8.9 2.2 6.8 8.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 KII88899.1 - 2.9 6.3 12.2 3.4 6.1 12.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hydin_ADK PF17213.3 KII88899.1 - 3 8.1 7.2 4.1 7.6 7.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3464 PF11947.8 KII88899.1 - 3.9 7.2 9.4 6.1 6.6 9.4 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4175 PF13779.6 KII88899.1 - 4.2 5.2 28.0 5 4.9 28.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) YabA PF06156.13 KII88899.1 - 6.2 7.5 12.5 6.6 7.4 8.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Suf PF05843.14 KII88899.1 - 9.5 6.1 17.5 13 5.7 17.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TMA7 PF09072.10 KII88900.1 - 9.3e-23 80.8 26.0 1e-22 80.7 26.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Peptidase_S9 PF00326.21 KII88901.1 - 2e-07 30.7 0.0 4.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BcsB PF03170.13 KII88901.1 - 0.005 15.3 0.0 0.0082 14.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit Abhydrolase_6 PF12697.7 KII88901.1 - 0.0077 16.9 2.8 0.0077 16.9 2.8 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tannase PF07519.11 KII88901.1 - 0.014 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KII88901.1 - 0.02 14.2 0.1 0.061 12.6 0.1 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KII88901.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 KII88901.1 - 0.034 13.8 0.2 0.097 12.3 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Not1 PF04054.15 KII88902.1 - 8.2e-128 426.4 0.1 1.6e-127 425.5 0.1 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KII88902.1 - 1.1e-92 309.5 0.7 1.1e-92 309.5 0.7 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KII88902.1 - 5.4e-55 185.3 1.6 1.4e-54 184.0 1.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KII88902.1 - 3.6e-52 176.3 0.2 9.7e-52 174.9 0.0 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KII88902.1 - 5.2e-45 153.2 0.2 1.3e-44 151.9 0.2 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Sugar_tr PF00083.24 KII88903.1 - 6.9e-78 262.5 8.6 8.5e-78 262.2 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII88903.1 - 8.2e-23 80.9 25.1 8.2e-23 80.9 25.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII88903.1 - 6.7e-06 25.6 5.2 6.7e-06 25.6 5.2 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Alpha-amylase PF00128.24 KII88904.1 - 5.2e-53 180.8 0.1 1.1e-52 179.7 0.1 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KII88904.1 - 1.8e-15 57.0 0.2 5.9e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.16 KII88904.1 - 0.0043 15.3 0.2 0.017 13.3 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 HOOK PF05622.12 KII88905.1 - 1.6e-66 225.0 68.6 1.1e-63 215.5 43.6 2.9 1 1 1 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.12 KII88905.1 - 0.004 17.2 84.6 0.19 11.8 0.3 8.2 5 2 2 7 7 7 5 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 KII88905.1 - 0.0067 15.9 22.0 0.0067 15.9 22.0 5.1 2 2 2 5 5 5 1 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 KII88905.1 - 0.0079 16.3 2.1 0.0079 16.3 2.1 9.1 9 1 2 11 11 11 1 bZIP transcription factor NYD-SP28_assoc PF14775.6 KII88905.1 - 0.01 15.9 1.4 0.01 15.9 1.4 5.3 4 0 0 4 4 4 0 Sperm tail C-terminal domain HIP1_clath_bdg PF16515.5 KII88905.1 - 0.019 15.6 4.6 0.019 15.6 4.6 7.8 4 2 5 9 9 9 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 KII88905.1 - 6.8 7.1 73.5 0.25 11.8 5.2 5.1 2 2 3 5 5 5 0 Fez1 DUF973 PF06157.11 KII88906.1 - 0.019 14.0 2.1 0.027 13.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3377 PF11857.8 KII88906.1 - 0.28 11.1 2.1 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Tetraspanin PF00335.20 KII88906.1 - 2.9 7.6 10.4 4.4 6.9 10.3 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF4260 PF14079.6 KII88906.1 - 4.4 7.3 9.6 0.55 10.2 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4260) Tetraspanin PF00335.20 KII88907.1 - 0.007 16.1 12.6 0.011 15.5 12.6 1.5 1 1 0 1 1 1 1 Tetraspanin family RTC PF01137.21 KII88908.1 - 1e-81 273.4 0.0 1.2e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KII88908.1 - 1.6e-21 76.7 0.7 3.7e-21 75.6 0.7 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SH3_9 PF14604.6 KII88908.1 - 0.13 12.2 0.2 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Variant SH3 domain CDC50 PF03381.15 KII88909.1 - 1.5e-95 319.9 0.1 2.1e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family NAD_binding_7 PF13241.6 KII88910.1 - 2.4e-30 105.0 0.1 7.9e-30 103.4 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KII88910.1 - 4e-22 77.6 0.1 6.1e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KII88910.1 - 3e-16 58.6 0.8 6.4e-16 57.5 0.8 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.21 KII88910.1 - 0.017 14.5 1.9 0.059 12.7 0.1 2.3 1 1 1 2 2 2 0 ThiF family Endonuclease_NS PF01223.23 KII88911.1 - 3.7e-55 187.2 0.0 4.8e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease MRP-L46 PF11788.8 KII88912.1 - 3e-18 66.7 1.5 5.3e-18 65.9 1.5 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KII88912.1 - 2.5e-05 24.3 0.2 8.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF3558 PF12079.8 KII88912.1 - 0.5 10.3 4.0 2.3 8.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) V-ATPase_H_N PF03224.14 KII88913.1 - 1.4e-85 287.4 0.0 3.1e-85 286.3 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KII88913.1 - 1.3e-45 154.2 0.6 5.7e-45 152.2 0.3 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 KII88913.1 - 0.0041 17.2 1.2 0.48 10.8 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Arm_2 PF04826.13 KII88913.1 - 0.0091 15.5 0.3 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 Armadillo-like Uso1_p115_head PF04869.14 KII88913.1 - 0.031 13.4 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.6 KII88913.1 - 0.031 14.7 0.6 0.19 12.2 0.1 2.5 2 1 0 2 2 2 0 HEAT repeats DUF974 PF06159.13 KII88914.1 - 1.8e-78 263.8 0.0 2.4e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) 60KD_IMP PF02096.20 KII88915.1 - 2.5e-11 43.7 6.9 3.4e-11 43.3 6.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein FAD-oxidase_C PF02913.19 KII88916.1 - 6.3e-53 180.0 0.1 1.4e-52 178.9 0.1 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KII88916.1 - 1.9e-30 105.5 0.5 3.3e-30 104.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Bmt2 PF11968.8 KII88917.1 - 1.6e-63 214.5 0.0 2.1e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KII88917.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MBF1 PF08523.10 KII88918.1 - 2e-28 98.6 4.5 3.6e-28 97.8 4.2 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KII88918.1 - 5.9e-11 42.3 0.1 9.6e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KII88918.1 - 0.059 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 KII88919.1 - 1.1e-67 228.1 0.0 2.2e-67 227.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KII88919.1 - 2.8e-46 156.8 0.3 5.6e-46 155.8 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KII88919.1 - 0.00063 20.0 0.0 0.0029 17.9 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KII88919.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RNA12 PF10443.9 KII88921.1 - 1.5e-117 393.0 0.0 5.1e-65 219.9 0.1 2.1 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 KII88921.1 - 3.4e-05 24.3 1.0 0.00013 22.4 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 KII88921.1 - 0.00014 21.8 0.0 0.00067 19.6 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 KII88921.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_33 PF13671.6 KII88921.1 - 0.0068 16.6 0.5 0.73 10.0 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KII88921.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII88921.1 - 0.021 14.3 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KII88921.1 - 0.032 14.2 0.0 0.22 11.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KII88921.1 - 0.055 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KII88921.1 - 0.084 13.4 0.2 0.34 11.4 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA PF00004.29 KII88921.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KII88921.1 - 2 8.2 5.0 0.89 9.3 1.8 2.1 1 1 1 2 2 2 0 AAA domain MTABC_N PF16185.5 KII88922.1 - 0.024 14.2 4.3 0.041 13.4 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region CitMHS PF03600.16 KII88922.1 - 0.032 13.5 3.3 0.046 12.9 3.3 1.4 1 0 0 1 1 1 0 Citrate transporter Tetraspanin PF00335.20 KII88922.1 - 0.37 10.5 16.4 1 9.0 16.5 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF4191 PF13829.6 KII88922.1 - 1.1 8.5 4.9 4.9 6.4 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3149 PF11346.8 KII88922.1 - 2.2 8.0 7.6 33 4.2 3.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) SieB PF14163.6 KII88922.1 - 5.6 6.5 8.2 17 4.9 5.6 2.7 2 1 0 2 2 2 0 Super-infection exclusion protein B DUF2420 PF10336.9 KII88923.1 - 3.9e-10 39.7 0.0 7.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) 5_nucleotid_C PF02872.18 KII88925.1 - 5e-24 85.3 0.0 9.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KII88925.1 - 2.2e-08 34.8 0.2 3.7e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_9 PF08221.11 KII88926.1 - 1e-16 60.8 0.4 8e-14 51.5 0.3 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 KII88926.1 - 2.2e-14 53.9 0.7 1.7e-12 47.6 1.8 2.6 2 1 1 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 KII88926.1 - 1.3e-10 41.1 0.0 1.5e-07 31.2 0.0 4.3 4 1 1 5 5 5 1 TFIIE alpha subunit XPA_C PF05181.12 KII88927.1 - 0.0059 16.6 0.3 0.013 15.5 0.3 1.6 1 1 0 1 1 1 1 XPA protein C-terminus Plavaka PF18759.1 KII88928.1 - 2.1e-125 418.2 0.1 3.1e-125 417.7 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KII88928.1 - 0.015 16.1 0.1 0.015 16.1 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KII88928.1 - 0.036 14.5 0.4 0.036 14.5 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KII88928.1 - 0.087 12.6 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type Hs1pro-1_N PF07231.12 KII88929.1 - 0.017 14.9 0.3 0.03 14.1 0.3 1.3 1 0 0 1 1 1 0 Hs1pro-1 N-terminus Tropomodulin PF03250.14 KII88930.1 - 0.09 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Tropomodulin TMA7 PF09072.10 KII88931.1 - 8.8e-18 64.9 14.4 1.2e-17 64.5 14.4 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 Metallophos PF00149.28 KII88933.1 - 8.6e-11 42.7 0.0 3.7e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII88933.1 - 2.8e-06 27.6 0.1 4.5e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KII88933.1 - 0.0089 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily SPT16 PF08644.11 KII88934.1 - 7.6e-57 191.7 0.3 7.6e-57 191.7 0.3 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KII88934.1 - 1.2e-44 152.0 0.0 3.2e-44 150.6 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KII88934.1 - 3.1e-26 92.4 0.0 5.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KII88934.1 - 5.7e-15 55.5 0.0 1.5e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF4875 PF16175.5 KII88934.1 - 0.03 14.5 0.7 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4875) DUF3956 PF13104.6 KII88934.1 - 0.044 14.0 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) TF_Zn_Ribbon PF08271.12 KII88936.1 - 0.0035 16.8 0.6 0.0072 15.8 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding CENP-B_dimeris PF09026.10 KII88936.1 - 0.91 10.0 5.5 2.5 8.5 5.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Abhydrolase_1 PF00561.20 KII88937.1 - 2.5e-19 69.9 0.0 5.7e-18 65.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII88937.1 - 1.4e-16 60.5 0.0 1.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII88937.1 - 1e-15 58.9 0.8 1.4e-15 58.5 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KII88937.1 - 7.1e-07 29.3 0.3 3.8e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KII88937.1 - 0.0015 18.6 0.0 0.0046 17.0 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.7 KII88937.1 - 0.03 14.1 0.1 3 7.6 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII88937.1 - 0.052 13.0 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KII88937.1 - 0.057 12.9 0.1 0.71 9.3 0.2 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 KII88937.1 - 0.066 12.9 0.0 0.34 10.5 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 KII88937.1 - 0.11 12.4 0.0 2 8.3 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KII88937.1 - 0.13 12.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DEAD PF00270.29 KII88939.1 - 7.6e-22 77.9 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII88939.1 - 8.1e-17 61.6 0.0 2.9e-13 50.1 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF1998 PF09369.10 KII88939.1 - 2.1e-15 57.2 0.2 8.9e-15 55.2 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 KII88939.1 - 2.8e-06 27.8 0.0 4.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KII88939.1 - 4.4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KII88940.1 - 2.5e-21 76.2 0.0 4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII88940.1 - 2.9e-11 43.2 0.0 8.6e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase NYN PF01936.18 KII88941.1 - 4.9e-23 82.2 0.0 6.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 NYN domain Arrestin_C PF02752.22 KII88947.1 - 0.00056 20.4 0.0 0.24 11.9 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KII88947.1 - 0.035 14.2 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain NAD_binding_2 PF03446.15 KII88948.1 - 8e-37 126.8 0.0 1.2e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KII88948.1 - 1e-29 103.2 0.0 6e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KII88948.1 - 0.002 18.7 0.0 0.0065 17.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KII88948.1 - 0.06 12.3 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DNA_pol_D_N PF18018.1 KII88950.1 - 1.8e-40 138.1 0.0 2.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KII88950.1 - 2.8e-31 108.5 0.5 1.7e-30 106.0 0.5 2.0 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NYN PF01936.18 KII88951.1 - 8.6e-25 87.9 0.0 1.6e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 NYN domain 40S_S4_C PF16121.5 KII88951.1 - 0.062 12.9 0.2 11 5.8 0.0 3.2 3 0 0 3 3 3 0 40S ribosomal protein S4 C-terminus NYN PF01936.18 KII88952.1 - 2.9e-23 83.0 0.0 1.5e-22 80.7 0.0 2.2 3 0 0 3 3 3 1 NYN domain CHCH PF06747.13 KII88953.1 - 0.00021 21.3 0.1 0.00039 20.5 0.2 1.4 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KII88953.1 - 0.003 17.5 0.3 0.0045 17.0 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like UQ_con PF00179.26 KII88954.1 - 1.1e-18 67.2 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4658 PF15555.6 KII88954.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) RWD PF05773.22 KII88954.1 - 0.032 14.5 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-RanBP PF00641.18 KII88954.1 - 2.6 7.5 4.7 0.59 9.5 0.7 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP21_like_P PF12230.8 KII88956.1 - 8.5e-48 163.1 12.5 8.5e-48 163.1 12.5 2.4 3 1 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KII88956.1 - 1.2e-35 121.2 1.2 2.3e-17 62.7 0.1 2.7 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 KII88956.1 - 6.1e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 KII88956.1 - 0.00025 20.6 0.2 0.00057 19.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 KII88956.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like L31 PF09784.9 KII88957.1 - 6.4e-42 142.1 0.0 7.2e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 KII88958.1 - 9.2e-77 257.8 0.6 1.1e-76 257.5 0.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNase_T PF00929.24 KII88959.1 - 4.9e-14 53.2 0.0 4.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Exonuclease RepB-RCR_reg PF10723.9 KII88959.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Replication regulatory protein RepB DUF3082 PF11282.8 KII88960.1 - 0.49 10.7 2.7 26 5.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) Ndc80_HEC PF03801.13 KII88961.1 - 3.2e-30 104.8 0.0 7e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KII88961.1 - 0.00016 21.7 5.3 0.00016 21.7 5.3 4.1 3 2 0 3 3 3 1 Domain of unknown function (DUF5595) Herpes_UL82_83 PF05784.11 KII88961.1 - 0.068 12.0 0.5 1.3 7.8 0.2 2.1 2 0 0 2 2 2 0 Betaherpesvirus UL82/83 protein N terminus DUF2935 PF11155.8 KII88961.1 - 0.26 11.6 5.9 1.9 8.9 0.4 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Vps51 PF08700.11 KII88961.1 - 0.39 10.8 4.9 31 4.7 0.0 4.1 3 1 0 3 3 3 0 Vps51/Vps67 DUF2730 PF10805.8 KII88961.1 - 1.6 8.9 13.9 13 6.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.12 KII88961.1 - 2.1 8.9 9.5 4.5 7.8 0.3 4.1 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 KII88961.1 - 5.6 7.3 14.7 0.83 10.0 1.6 3.9 2 1 2 4 4 4 0 Uncharacterized conserved protein DUF1664 PF07889.12 KII88961.1 - 9 6.4 19.1 2.3 8.3 2.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Mog1 PF04603.12 KII88962.1 - 3.4e-41 140.8 0.0 4e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Ran-interacting Mog1 protein PaREP1 PF05942.11 KII88963.1 - 0.0003 20.7 0.1 0.0003 20.7 0.1 2.0 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Cnn_1N PF07989.11 KII88963.1 - 0.063 13.4 11.8 0.15 12.2 0.2 3.2 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 NRBF2_MIT PF17169.4 KII88963.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.5 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 DUF2383 PF09537.10 KII88963.1 - 0.14 12.5 10.4 0.43 10.9 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Sox_N PF12444.8 KII88963.1 - 0.57 11.3 7.6 0.74 11.0 0.0 3.6 3 0 0 3 3 3 0 Sox developmental protein N terminal YabA PF06156.13 KII88963.1 - 1.4 9.6 11.7 4.5 8.0 0.8 3.0 3 0 0 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 KII88963.1 - 3 8.4 19.5 1.8 9.0 2.1 4.0 3 1 0 3 3 3 0 Cell division protein ZapB MctB PF11382.8 KII88963.1 - 3.9 7.1 6.5 73 2.9 0.0 3.7 4 0 0 4 4 4 0 Copper transport outer membrane protein, MctB Fib_alpha PF08702.10 KII88963.1 - 9 6.5 7.8 5.5 7.2 1.1 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DivIVA PF05103.13 KII88963.1 - 9.6 6.3 20.7 0.36 10.9 1.7 2.7 3 0 0 3 3 3 0 DivIVA protein DUF3450 PF11932.8 KII88963.1 - 9.6 5.4 15.9 0.11 11.8 3.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) HECT PF00632.25 KII88965.1 - 3e-93 312.7 0.0 3.8e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KII88965.1 - 8.2e-37 125.0 19.1 2.7e-13 49.7 5.1 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KII88965.1 - 1.4e-19 70.3 0.1 3.4e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain Pox_MCEL PF03291.16 KII88966.1 - 2.8e-85 286.4 0.0 3.5e-84 282.8 0.0 2.0 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KII88966.1 - 2.2e-13 50.7 0.0 5.1e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII88966.1 - 8.4e-10 38.6 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII88966.1 - 1.2e-09 38.8 0.0 1.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII88966.1 - 1e-08 35.7 0.0 2.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII88966.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KII88966.1 - 0.001 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family TPMT PF05724.11 KII88966.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KII88966.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ERAP1_C PF11838.8 KII88967.1 - 8.8e-71 239.0 0.6 1.6e-70 238.2 0.6 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KII88967.1 - 1.9e-69 233.6 0.0 3.2e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KII88967.1 - 4e-41 141.3 0.1 8.5e-39 133.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain Exonuc_VIII PF06630.11 KII88967.1 - 0.0078 16.1 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 1 Enterobacterial exodeoxyribonuclease VIII DUF3458 PF11940.8 KII88967.1 - 0.11 12.9 0.1 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold DDE_Tnp_IS240 PF13610.6 KII88967.1 - 0.12 12.6 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 DDE domain TEA PF01285.18 KII88969.1 - 8e-25 86.7 0.0 1.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Lipase_GDSL_2 PF13472.6 KII88970.1 - 3.4e-29 102.5 0.1 5.3e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII88970.1 - 1.1e-16 61.4 0.0 1.6e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Telomere_reg-2 PF10193.9 KII88971.1 - 2e-32 111.9 0.0 5.5e-32 110.5 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein 2Fe-2S_thioredx PF01257.19 KII88972.1 - 3.1e-59 199.0 0.0 3.8e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.21 KII88973.1 - 1.5e-36 126.3 0.0 1.6e-20 73.7 0.0 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2545 PF10810.8 KII88973.1 - 0.0074 16.4 0.8 0.017 15.3 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2545) Rhodanese PF00581.20 KII88974.1 - 1.2e-13 51.5 0.0 4.7e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain adh_short PF00106.25 KII88976.1 - 4.3e-26 91.6 0.1 5.9e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII88976.1 - 7.4e-22 78.0 0.1 9.3e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88976.1 - 3.1e-07 30.5 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII88976.1 - 0.00034 20.6 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII88976.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KII88976.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Glyco_hydro_15 PF00723.21 KII88977.1 - 2.9e-91 306.5 0.0 3.4e-91 306.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KII88977.1 - 2e-23 82.1 0.3 4.5e-23 81.0 0.3 1.6 1 0 0 1 1 1 1 Starch binding domain Cpn60_TCP1 PF00118.24 KII88978.1 - 4.4e-149 497.3 13.1 5e-149 497.1 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KII88978.1 - 0.0021 17.6 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination Arteri_nsp7a PF16749.5 KII88978.1 - 0.073 13.3 0.1 2.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Arterivirus nonstructural protein 7 alpha SCAB_CC PF16712.5 KII88978.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein TPR_2 PF07719.17 KII88979.1 - 7.3e-22 75.7 13.8 7e-05 22.6 0.2 10.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 KII88979.1 - 1.7e-19 68.7 4.8 1.6e-07 30.8 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KII88979.1 - 1e-18 67.3 8.6 1.8e-13 50.5 0.7 5.4 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KII88979.1 - 1.9e-14 52.9 3.2 0.13 12.7 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KII88979.1 - 2.1e-11 43.1 4.9 0.15 12.3 0.1 8.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII88979.1 - 2.4e-11 44.0 10.8 0.44 11.1 0.0 7.8 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KII88979.1 - 5e-10 39.4 10.5 0.16 12.9 0.0 9.7 5 1 5 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII88979.1 - 5.3e-10 39.4 7.1 0.00026 21.2 0.1 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII88979.1 - 1.6e-08 34.1 6.0 0.18 11.5 0.0 6.9 5 2 3 8 8 8 3 TPR repeat TPR_6 PF13174.6 KII88979.1 - 6.1e-08 32.8 2.1 7.2 7.5 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII88979.1 - 2.7e-05 24.7 24.2 3.7e-05 24.3 0.1 8.0 8 2 1 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII88979.1 - 6.4e-05 23.0 3.5 0.0088 16.2 0.0 4.7 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KII88979.1 - 0.33 11.3 3.2 28 5.1 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Aldolase_II PF00596.21 KII88980.1 - 7.4e-47 159.7 0.1 9.2e-47 159.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain G-patch PF01585.23 KII88981.1 - 2.8e-07 30.3 1.5 7e-07 29.0 1.5 1.7 1 0 0 1 1 1 1 G-patch domain FAD_binding_2 PF00890.24 KII88982.1 - 1.8e-126 422.6 1.8 2.2e-126 422.3 1.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KII88982.1 - 3.3e-42 143.5 0.2 4.9e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KII88982.1 - 6.8e-06 25.5 0.2 0.00075 18.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII88982.1 - 1.5e-05 24.3 0.2 0.015 14.6 0.0 2.7 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KII88982.1 - 3.2e-05 23.2 2.3 0.012 14.7 1.8 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KII88982.1 - 0.0022 17.3 0.2 0.0038 16.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII88982.1 - 0.087 12.4 1.4 0.25 10.9 1.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII88982.1 - 0.094 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KII88982.1 - 0.31 9.7 2.5 0.72 8.5 0.4 2.5 4 0 0 4 4 4 0 HI0933-like protein RabGAP-TBC PF00566.18 KII88983.1 - 1.5e-28 99.9 0.1 4e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Fungal_trans PF04082.18 KII88984.1 - 1.2e-14 54.1 0.2 4.6e-14 52.1 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII88984.1 - 5e-05 23.3 11.0 8e-05 22.7 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5450 PF17529.2 KII88984.1 - 0.89 9.7 3.5 1.6 8.8 3.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5450) RsfS PF02410.15 KII88987.1 - 6.8e-05 23.2 0.0 0.0001 22.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SHR3_chaperone PF08229.11 KII88988.1 - 4.8e-42 143.1 0.0 5.9e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 KII88988.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5453) DUF4094 PF13334.6 KII88988.1 - 0.11 12.9 0.1 0.73 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) YrhK PF14145.6 KII88988.1 - 0.18 11.7 2.5 0.41 10.6 0.3 2.2 2 0 0 2 2 2 0 YrhK-like protein LETM1 PF07766.13 KII88989.1 - 1.8e-103 345.5 0.1 1.8e-103 345.5 0.1 2.2 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KII88989.1 - 4.9e-05 23.0 0.1 0.0014 18.4 0.0 3.2 3 0 0 3 3 3 1 SAP domain EF-hand_7 PF13499.6 KII88989.1 - 0.00076 19.9 1.1 0.012 16.1 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KII88989.1 - 0.0043 16.5 0.0 0.053 13.1 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KII88989.1 - 0.0057 16.5 0.0 1.7 8.8 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KII88989.1 - 0.025 14.4 0.8 0.08 12.8 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 KII88989.1 - 0.028 13.9 0.1 0.5 10.0 0.0 2.9 2 0 0 2 2 2 0 EF hand ALMT PF11744.8 KII88989.1 - 2.1 7.1 6.9 3.3 6.4 6.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Glycos_transf_1 PF00534.20 KII88991.1 - 7.5e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KII88991.1 - 1e-12 48.6 0.0 1.7e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KII88991.1 - 5.9e-06 26.6 0.0 1.8e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KII88991.1 - 0.0035 17.8 0.1 0.67 10.4 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KII88991.1 - 0.014 15.4 0.0 0.072 13.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 2OG-FeII_Oxy_2 PF13532.6 KII88992.1 - 4e-35 121.8 0.0 1.3e-34 120.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAP PF07174.11 KII88992.1 - 8.2 5.8 13.2 13 5.1 13.2 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DNA_pol_phi PF04931.13 KII88994.1 - 1.6e-236 787.1 16.3 1.6e-236 787.1 16.3 2.3 2 0 0 2 2 2 1 DNA polymerase phi DUF4195 PF13836.6 KII88994.1 - 0.044 13.9 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) MutS_V PF00488.21 KII88995.1 - 3.9e-68 229.2 1.0 1.1e-67 227.7 0.3 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KII88995.1 - 9.1e-38 130.4 0.1 2e-37 129.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KII88995.1 - 2.9e-27 95.1 0.0 6.5e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KII88995.1 - 4.4e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KII88995.1 - 7.9e-07 29.3 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV ACC_epsilon PF13822.6 KII88995.1 - 0.068 13.9 2.7 0.43 11.3 0.0 3.8 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit ATP12 PF07542.11 KII88996.1 - 2e-39 134.6 0.5 3e-39 134.1 0.1 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein BCAS2 PF05700.11 KII88996.1 - 0.036 13.8 0.3 0.036 13.8 0.3 1.7 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3025 PF11227.8 KII88996.1 - 0.051 13.4 2.6 0.32 10.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3025) LamB_YcsF PF03746.16 KII88996.1 - 0.057 13.1 0.2 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 LamB/YcsF family DUF3828 PF12883.7 KII88996.1 - 0.13 12.6 0.3 0.23 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) adh_short PF00106.25 KII88997.1 - 5.7e-23 81.4 0.2 7.6e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII88997.1 - 2.1e-19 70.0 2.0 2.5e-19 69.8 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII88997.1 - 9.2e-11 42.0 0.0 1.2e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII88997.1 - 6.9e-06 25.7 0.0 2.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII88997.1 - 0.0019 18.2 1.5 0.0035 17.2 1.5 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KII88997.1 - 0.049 13.6 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family p450 PF00067.22 KII88998.1 - 1.4e-62 212.0 0.0 1.8e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nt_Gln_amidase PF09764.9 KII89001.1 - 2.3e-43 148.0 0.0 2.8e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase BTB PF00651.31 KII89002.1 - 0.00025 21.3 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HTH_32 PF13565.6 KII89004.1 - 1.5 9.5 7.2 12 6.5 0.0 4.3 4 0 0 4 4 4 0 Homeodomain-like domain UQ_con PF00179.26 KII89005.1 - 6.4e-42 142.5 0.1 7.2e-42 142.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII89005.1 - 0.00077 19.7 0.0 0.0009 19.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KII89005.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 KII89005.1 - 0.0037 17.0 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B SPRY PF00622.28 KII89006.1 - 6.3e-08 32.8 0.0 3.9e-05 23.7 0.0 2.9 3 0 0 3 3 3 2 SPRY domain PhoD PF09423.10 KII89007.1 - 0.0006 18.9 0.1 0.63 9.0 0.0 2.8 3 0 0 3 3 3 2 PhoD-like phosphatase CAP_N PF01213.19 KII89008.1 - 6.3e-112 374.2 1.3 6.3e-112 374.2 1.3 1.8 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KII89008.1 - 8e-55 184.8 8.4 1.1e-54 184.4 8.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KII89008.1 - 0.0058 16.4 5.5 0.016 15.0 5.6 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C tRNA_int_endo PF01974.17 KII89009.1 - 1.1e-13 51.1 0.0 2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Rrn6 PF10214.9 KII89009.1 - 0.0051 15.4 0.7 0.0063 15.1 0.7 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor EI24 PF07264.11 KII89010.1 - 6.5e-37 127.5 12.1 9.7e-37 126.9 12.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Linker_histone PF00538.19 KII89011.1 - 7.5e-24 83.9 1.8 2.4e-23 82.3 0.0 2.5 2 0 0 2 2 2 1 linker histone H1 and H5 family RF-1 PF00472.20 KII89012.1 - 5.3e-21 74.7 4.5 5.3e-21 74.7 4.5 2.1 2 0 0 2 2 2 1 RF-1 domain DUF3474 PF11960.8 KII89012.1 - 0.089 13.0 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) B277 PF17623.2 KII89012.1 - 1.1 8.2 4.4 1.9 7.5 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF2924 PF11149.8 KII89012.1 - 1.6 9.1 5.6 0.73 10.2 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Aldo_ket_red PF00248.21 KII89013.1 - 1.8e-46 158.7 0.0 2.1e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Linker_histone PF00538.19 KII89014.1 - 2.4e-20 72.6 0.0 2.4e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family Aldo_ket_red PF00248.21 KII89017.1 - 1.4e-45 155.7 0.0 1.7e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 KII89018.1 - 7.1e-16 57.8 0.0 1.2e-15 57.0 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 KII89019.1 - 6.8e-25 87.2 0.3 3.3e-24 85.0 0.0 2.3 2 0 0 2 2 2 1 linker histone H1 and H5 family RRM_1 PF00076.22 KII89020.1 - 1.3e-25 89.0 0.0 1.4e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KII89020.1 - 2.7e-19 67.7 0.0 0.00027 20.5 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KII89020.1 - 1.7e-05 24.6 0.0 0.062 13.2 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KII89020.1 - 0.1 12.1 0.0 0.69 9.3 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif RCC1 PF00415.18 KII89024.1 - 6.8e-19 68.2 13.4 1.1e-07 32.4 0.2 8.1 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII89024.1 - 5.7e-11 41.9 20.2 1.2e-05 25.0 0.2 6.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat DUF4551 PF15087.6 KII89025.1 - 0.55 9.0 5.5 0.64 8.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DPBB_1 PF03330.18 KII89026.1 - 0.00014 22.0 0.0 0.00079 19.7 0.0 2.1 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 KII89026.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 Barwin family Apt1 PF10351.9 KII89026.1 - 0.87 8.4 7.8 1.1 8.0 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KII89026.1 - 6.3 5.9 19.1 7.8 5.6 19.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DPBB_1 PF03330.18 KII89027.1 - 0.00039 20.6 0.0 0.00089 19.5 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase DUF908 PF06012.12 KII89027.1 - 0.019 14.4 2.2 0.016 14.6 2.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Barwin PF00967.17 KII89027.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Barwin family SOG2 PF10428.9 KII89027.1 - 0.28 10.3 18.5 0.37 9.9 18.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MGC-24 PF05283.11 KII89027.1 - 0.85 10.1 15.2 1.6 9.2 15.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RAP1 PF07218.11 KII89027.1 - 2 6.6 12.6 2.5 6.3 12.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.12 KII89027.1 - 2.3 8.6 11.4 4.9 7.5 11.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 KII89027.1 - 8.9 5.0 6.6 11 4.7 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain E1-E2_ATPase PF00122.20 KII89028.1 - 1.2e-52 178.1 1.8 1.2e-52 178.1 1.8 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KII89028.1 - 6.7e-45 153.0 9.0 6.7e-45 153.0 9.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KII89028.1 - 2.9e-22 80.0 2.1 3.3e-21 76.5 2.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KII89028.1 - 3.5e-20 71.4 0.6 4e-19 68.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KII89028.1 - 4.9e-20 71.4 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KII89028.1 - 6.5e-07 29.3 1.4 4e-06 26.8 1.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KII89028.1 - 6.2e-06 26.7 0.0 2.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 KII89029.1 - 0.0052 16.6 8.4 0.0088 15.9 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 KII89029.1 - 0.17 12.3 0.6 0.39 11.2 0.6 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain CBP4 PF07960.11 KII89030.1 - 3.3e-11 43.1 0.0 3.9e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 CBP4 BRCT_2 PF16589.5 KII89031.1 - 1.7e-17 63.6 0.0 8e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KII89031.1 - 0.013 15.9 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PNK3P PF08645.11 KII89032.1 - 1e-44 152.1 0.0 1.3e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase LNS2 PF08235.13 KII89032.1 - 0.095 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Metallophos PF00149.28 KII89033.1 - 2.1e-09 38.2 0.1 3.6e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII89033.1 - 5.4e-07 29.9 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SHQ1 PF04925.15 KII89034.1 - 2.2e-57 193.5 0.0 3.2e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 KII89034.1 - 0.0011 19.4 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain PDEase_II PF02112.15 KII89037.1 - 0.16 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II PDEase_II PF02112.15 KII89038.1 - 2.9e-16 59.5 0.0 5.4e-16 58.6 0.0 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 KII89038.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Nuc_sug_transp PF04142.15 KII89039.1 - 8.4e-08 31.7 0.8 1e-07 31.5 0.8 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KII89039.1 - 1.2e-07 31.4 3.5 2.1e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 KII89039.1 - 2.3e-07 31.1 26.4 1.4e-05 25.3 2.0 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KII89039.1 - 1.6e-05 24.3 7.6 2.3e-05 23.8 7.6 1.2 1 0 0 1 1 1 1 UAA transporter family SMP_LBD PF17047.5 KII89039.1 - 0.039 13.4 0.2 0.064 12.7 0.2 1.3 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain CRT-like PF08627.10 KII89039.1 - 0.89 8.4 9.9 5.2 5.9 8.6 2.5 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like Arrestin_C PF02752.22 KII89040.1 - 0.1 13.0 0.0 1.1 9.7 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Peptidase_C14 PF00656.22 KII89041.1 - 6e-65 219.6 0.0 8.1e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Chorismate_bind PF00425.18 KII89042.1 - 1.5e-90 303.3 0.0 2.1e-90 302.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KII89042.1 - 6.8e-27 94.4 0.0 2.9e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 KII89043.1 - 2.5e-55 187.1 0.0 3.8e-31 108.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Phosphatase PF15698.5 KII89043.1 - 0.076 12.1 0.1 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 Phosphatase HSP70 PF00012.20 KII89044.1 - 3.5e-235 781.8 5.8 3.9e-235 781.6 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KII89044.1 - 2.2e-16 59.6 0.4 1.9e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 KII89044.1 - 0.0014 18.2 0.3 0.79 9.2 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 KII89044.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KII89044.1 - 0.017 14.1 0.1 0.17 10.8 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Zincin_2 PF10103.9 KII89044.1 - 0.034 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase StbA PF06406.11 KII89044.1 - 0.087 12.1 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 StbA protein ATP-synt_DE PF00401.20 KII89044.1 - 6.7 7.1 9.6 11 6.4 5.6 2.8 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain F-box-like PF12937.7 KII89045.1 - 0.0034 17.2 0.3 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII89045.1 - 0.098 13.1 2.5 24 5.5 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Amino_oxidase PF01593.24 KII89046.1 - 2e-60 205.4 0.3 5.1e-60 204.1 0.3 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII89046.1 - 2.4e-17 62.9 0.1 5.1e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII89046.1 - 5e-09 36.2 4.9 1.6e-08 34.5 4.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII89046.1 - 1.9e-06 27.2 0.4 1.9e-06 27.2 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KII89046.1 - 2.1e-06 27.2 0.1 4e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KII89046.1 - 2.2e-06 27.3 0.1 3.8e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KII89046.1 - 5.2e-06 25.4 1.9 7e-05 21.7 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KII89046.1 - 2.6e-05 23.6 0.9 0.00033 20.0 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII89046.1 - 3.9e-05 23.0 1.1 0.00019 20.8 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KII89046.1 - 0.00029 20.0 0.7 0.085 11.9 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 KII89046.1 - 0.0011 19.5 1.0 0.0049 17.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII89046.1 - 0.0036 16.4 0.1 0.0061 15.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KII89046.1 - 0.037 13.3 0.4 0.037 13.3 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII89046.1 - 0.57 10.2 2.6 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAA PF00004.29 KII89047.1 - 7.2e-15 55.6 0.0 2.2e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KII89047.1 - 7.5e-14 51.9 0.1 4.5e-13 49.4 0.1 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KII89047.1 - 5.2e-12 45.9 0.0 3.8e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KII89047.1 - 7.8e-08 32.4 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KII89047.1 - 7.1e-06 26.3 0.0 7.4e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KII89047.1 - 1.9e-05 24.9 0.0 4.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KII89047.1 - 4.7e-05 23.8 0.0 0.00034 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KII89047.1 - 5.9e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KII89047.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KII89047.1 - 0.00032 20.5 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KII89047.1 - 0.00038 20.4 0.0 0.0018 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KII89047.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KII89047.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 KII89047.1 - 0.0032 16.9 0.0 0.069 12.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KII89047.1 - 0.0062 16.6 0.0 0.023 14.7 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII89047.1 - 0.0075 16.6 0.0 0.048 14.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KII89047.1 - 0.015 15.5 0.4 0.075 13.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 KII89047.1 - 0.031 14.0 0.2 0.6 9.9 0.0 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase DUF2075 PF09848.9 KII89047.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 KII89047.1 - 0.047 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_2 PF07724.14 KII89047.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 KII89047.1 - 0.06 13.8 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KII89047.1 - 0.077 12.4 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KII89047.1 - 0.11 13.1 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII89047.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase CAF1A PF12253.8 KII89048.1 - 2.3e-21 75.7 2.3 2.3e-21 75.7 2.3 2.9 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A Peptidase_S64 PF08192.11 KII89048.1 - 0.23 9.9 6.7 0.39 9.2 6.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 RR_TM4-6 PF06459.12 KII89048.1 - 7 6.4 20.6 19 4.9 20.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_4 PF12799.7 KII89049.1 - 0.00081 19.7 0.0 1 9.9 0.0 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) RNase_H PF00075.24 KII89051.1 - 1.3e-05 25.4 0.1 2.5e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.27 KII89052.1 - 0.00011 21.8 0.1 0.00011 21.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 KII89055.1 - 4.7e-16 58.8 0.2 8.4e-16 58.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89055.1 - 1e-06 28.5 0.1 1.5e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89055.1 - 3.3e-06 27.1 0.3 5.5e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 KR domain SnoaL_4 PF13577.6 KII89055.1 - 0.076 13.1 0.0 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain GDP_Man_Dehyd PF16363.5 KII89055.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_oxidored PF12831.7 KII89055.1 - 0.14 11.5 0.4 0.17 11.2 0.4 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 KII89056.1 - 2e-13 50.2 0.2 3.5e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89056.1 - 2.5e-07 30.5 0.1 4.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89056.1 - 8.9e-05 22.5 0.2 0.00015 21.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Oxidored_FMN PF00724.20 KII89057.1 - 3.6e-70 236.9 0.0 5.5e-70 236.3 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N_2 PF13602.6 KII89058.1 - 3.2e-23 83.3 0.0 6.2e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89058.1 - 6.5e-10 39.1 0.0 1.5e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII89058.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_N PF08240.12 KII89058.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Pre-PUA PF17832.1 KII89059.1 - 9.6e-25 87.1 0.0 1.3e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KII89059.1 - 7.4e-16 57.9 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KII89059.1 - 0.0095 16.2 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) CRM1_C PF08767.11 KII89060.1 - 3.1e-131 437.3 0.2 3.1e-131 437.3 0.2 3.3 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KII89060.1 - 3.1e-42 144.1 9.6 7.9e-41 139.6 9.6 3.3 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KII89060.1 - 4.8e-34 115.8 4.2 1.2e-33 114.5 4.2 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KII89060.1 - 1.6e-30 105.0 1.4 1.6e-30 105.0 1.4 3.0 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KII89060.1 - 3.7e-19 67.9 2.6 3.7e-19 67.9 2.6 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KII89060.1 - 2e-14 53.2 0.0 8.7e-14 51.2 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KII89060.1 - 0.034 14.1 0.0 0.46 10.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) ADH_zinc_N_2 PF13602.6 KII89061.1 - 5.6e-22 79.2 0.0 1.2e-21 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89061.1 - 5.4e-16 58.8 0.2 3.4e-13 49.7 0.0 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII89061.1 - 0.0046 16.8 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 KII89061.1 - 0.0078 16.1 0.0 0.06 13.2 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Oxidored_FMN PF00724.20 KII89062.1 - 6.2e-62 209.8 0.0 7.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF346 PF03984.13 KII89062.1 - 0.0013 18.4 0.1 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF346) Pkinase_Tyr PF07714.17 KII89063.1 - 4.8e-44 150.6 0.0 6.5e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII89063.1 - 6.8e-44 150.2 0.0 9.6e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 KII89063.1 - 0.0058 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain APH PF01636.23 KII89063.1 - 0.024 14.6 0.1 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII89063.1 - 0.078 11.7 1.4 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase SRR1 PF07985.12 KII89065.1 - 4.8e-17 61.7 0.0 9.4e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 SRR1 RNA_pol_L_2 PF13656.6 KII89066.1 - 2.5e-29 100.8 0.0 3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KII89066.1 - 2.9e-08 33.0 0.0 4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short PF00106.25 KII89067.1 - 1.1e-14 54.3 0.2 2e-14 53.5 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89067.1 - 4.8e-08 32.8 0.0 7.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89067.1 - 0.0048 16.8 0.9 0.0073 16.2 0.9 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KII89067.1 - 0.043 13.1 0.1 0.074 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_oxidored PF12831.7 KII89067.1 - 0.11 11.8 0.9 0.14 11.4 0.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.32 KII89068.1 - 6.6e-14 52.1 3.4 0.0066 17.3 0.0 6.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89068.1 - 0.00016 21.9 0.0 0.9 9.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII89068.1 - 0.0011 18.0 0.0 0.33 9.9 0.0 2.8 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 KII89069.1 - 9.9e-15 54.5 0.8 1.5e-14 53.9 0.8 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89069.1 - 6.1e-10 39.1 0.1 1.6e-09 37.7 0.2 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89069.1 - 0.00022 21.2 1.5 0.00035 20.5 1.5 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KII89069.1 - 0.016 14.5 0.2 0.032 13.6 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 KII89069.1 - 0.14 11.8 0.5 0.32 10.6 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KII89069.1 - 0.15 12.0 1.5 0.23 11.3 1.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KII89070.1 - 2.3e-13 50.1 3.6 3.4e-13 49.5 1.8 2.0 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89070.1 - 2.6e-07 30.4 2.0 1.1e-06 28.4 1.2 2.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89070.1 - 3.6e-06 27.0 0.2 8e-06 25.9 0.1 1.5 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 KII89070.1 - 0.073 13.0 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 KII89070.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KII89070.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 KII89070.1 - 0.14 11.5 0.2 0.28 10.5 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KII89071.1 - 3.5e-15 56.0 0.1 4.5e-14 52.4 0.2 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII89071.1 - 8.1e-08 32.1 0.0 7e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89071.1 - 0.00042 20.3 1.2 0.00065 19.7 1.2 1.2 1 0 0 1 1 1 1 KR domain zf-MYND PF01753.18 KII89072.1 - 1.7e-08 34.4 10.9 3.2e-08 33.5 10.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII89072.1 - 7.5 7.0 11.4 15 6.0 11.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Spc24 PF08286.11 KII89073.1 - 1e-17 64.2 0.1 1e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Hemagglutinin PF00509.18 KII89073.1 - 0.031 12.7 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin YscO-like PF16789.5 KII89073.1 - 0.061 13.4 0.9 0.31 11.1 0.2 2.0 2 0 0 2 2 2 0 YscO-like protein FAM76 PF16046.5 KII89073.1 - 0.085 12.2 0.5 0.11 11.8 0.5 1.1 1 0 0 1 1 1 0 FAM76 protein OmpH PF03938.14 KII89073.1 - 0.95 9.8 5.3 2.8 8.3 5.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) M PF02370.16 KII89073.1 - 3.5 8.5 8.0 3.6 8.5 0.6 2.9 2 0 0 2 2 2 0 M protein repeat Spc7 PF08317.11 KII89073.1 - 5.4 5.8 7.2 4.4 6.1 3.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KII89073.1 - 5.5 7.5 10.0 14 6.2 10.0 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Chs7 PF12271.8 KII89074.1 - 7.8e-114 379.9 23.4 9e-114 379.7 23.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone GATA PF00320.27 KII89075.1 - 7.1e-15 54.3 5.9 1.3e-14 53.5 5.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KII89075.1 - 9.1e-06 25.9 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KII89075.1 - 9.2e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KII89075.1 - 0.00071 19.8 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_12 PF18095.1 KII89075.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain Zn-ribbon_8 PF09723.10 KII89075.1 - 0.022 14.9 0.2 0.053 13.6 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF4428 PF14471.6 KII89075.1 - 0.5 10.3 2.5 0.47 10.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) adh_short_C2 PF13561.6 KII89076.1 - 8e-57 192.5 0.2 1.1e-56 192.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII89076.1 - 1.1e-41 142.4 0.7 4.8e-41 140.4 0.9 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KII89076.1 - 1.4e-11 44.7 0.2 3.7e-11 43.3 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KII89076.1 - 2.9e-06 26.9 0.1 5.2e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KII89076.1 - 0.00064 19.0 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 KII89076.1 - 0.059 12.7 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 ThiF family Kinesin PF00225.23 KII89077.1 - 6.7e-97 324.4 0.0 5.5e-56 189.9 0.0 4.1 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 KII89077.1 - 3.9e-23 82.1 0.0 1.4e-22 80.2 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding DUF641 PF04859.12 KII89077.1 - 0.19 12.1 0.1 0.19 12.1 0.1 14.4 5 3 9 16 16 16 0 Plant protein of unknown function (DUF641) WD40 PF00400.32 KII89078.1 - 1.3e-59 196.7 10.1 5.8e-10 39.6 0.0 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89078.1 - 1.2e-20 73.6 0.5 9.6e-06 25.8 0.0 5.7 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII89078.1 - 3.3e-09 36.0 0.8 0.059 12.0 0.0 5.6 3 1 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KII89078.1 - 0.00019 20.3 0.8 1.6 7.4 0.0 3.8 2 1 2 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 KII89078.1 - 0.0003 19.9 0.1 0.45 9.4 0.0 3.3 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KII89078.1 - 0.0022 17.1 0.0 0.14 11.1 0.0 2.8 2 1 1 3 3 3 1 Coatomer WD associated region bZIP_2 PF07716.15 KII89078.1 - 0.051 13.7 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper DUF3906 PF13046.6 KII89078.1 - 0.054 13.6 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) PEP_hydrolase PF09370.10 KII89079.1 - 4.4e-132 439.2 0.6 5e-132 439.0 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like AP_endonuc_2 PF01261.24 KII89079.1 - 0.00028 20.4 0.1 0.00044 19.8 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NMO PF03060.15 KII89079.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase hnRNP_Q_AcD PF18360.1 KII89079.1 - 0.13 12.2 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain UPF0261 PF06792.11 KII89080.1 - 2.5e-135 451.5 5.1 2.8e-135 451.4 5.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Alba PF01918.21 KII89080.1 - 0.039 13.8 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Alba YTH PF04146.15 KII89081.1 - 1.3e-40 139.0 0.0 3.5e-40 137.6 0.0 1.8 1 0 0 1 1 1 1 YT521-B-like domain p450 PF00067.22 KII89082.1 - 9.6e-70 235.6 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ATP_bind_3 PF01171.20 KII89083.1 - 2.1e-39 135.1 0.0 2.9e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Abhydrolase_1 PF00561.20 KII89084.1 - 1.1e-14 54.8 0.0 4.4e-14 52.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII89084.1 - 6.4e-10 38.7 0.0 1.9e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII89084.1 - 1.3e-09 39.0 1.7 1.6e-09 38.7 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII89084.1 - 0.001 18.6 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KII89084.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KII89084.1 - 0.041 13.5 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KII89084.1 - 0.085 12.7 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KII89084.1 - 0.18 11.7 0.0 18 5.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 KII89085.1 - 2.5e-14 53.6 0.0 4.5e-14 52.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII89085.1 - 6.7e-11 43.2 1.9 8.3e-11 42.9 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII89085.1 - 4.9e-09 35.8 0.0 1.7e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII89085.1 - 0.018 14.5 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KII89085.1 - 0.046 13.5 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 KII89085.1 - 0.15 11.7 0.0 0.53 9.9 0.0 1.9 2 1 1 3 3 3 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 KII89085.1 - 0.17 11.8 0.0 9.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ndr PF03096.14 KII89085.1 - 0.28 9.8 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family SRP40_C PF05022.12 KII89086.1 - 1e-27 96.8 0.9 1.1e-27 96.6 0.9 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain UB2H PF14814.6 KII89086.1 - 0.11 12.6 0.1 0.21 11.6 0.1 1.5 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain DMRL_synthase PF00885.19 KII89087.1 - 6.9e-56 188.0 0.0 9e-56 187.6 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TolB_N PF04052.13 KII89087.1 - 0.083 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 TolB amino-terminal domain Gtr1_RagA PF04670.12 KII89088.1 - 5.1e-84 281.3 0.0 7.2e-84 280.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KII89088.1 - 1.2e-07 31.5 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89088.1 - 2.7e-07 30.8 0.0 5.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII89088.1 - 4.1e-06 26.4 0.0 6.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII89088.1 - 2.7e-05 24.2 0.0 4.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KII89088.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KII89088.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII89088.1 - 0.13 12.1 0.1 4 7.3 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Na_Ca_ex PF01699.24 KII89089.1 - 1.2e-41 142.2 30.7 1.1e-21 77.4 13.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein His_Phos_1 PF00300.22 KII89090.1 - 4.7e-37 127.6 0.0 4.3e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PFU PF09070.11 KII89092.1 - 4.1e-45 152.7 0.2 8.6e-45 151.6 0.2 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KII89092.1 - 1.7e-40 139.0 0.0 2.3e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KII89092.1 - 9.6e-33 111.7 13.9 1.3e-08 35.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 KII89092.1 - 5e-05 23.3 0.0 0.62 10.1 0.0 2.9 1 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.18 KII89093.1 - 8e-64 215.1 0.0 1.5e-63 214.2 0.0 1.5 1 0 0 1 1 1 1 HORMA domain MarR PF01047.22 KII89093.1 - 0.18 11.7 0.1 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 MarR family Sybindin PF04099.12 KII89095.1 - 3.7e-39 133.9 0.0 4.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KII89095.1 - 5.1e-08 33.1 0.0 6.4e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Lipocalin_7 PF14651.6 KII89095.1 - 0.068 13.1 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family TATR PF03430.13 KII89095.1 - 0.16 10.3 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_M28 PF04389.17 KII89096.1 - 2.3e-36 125.3 0.0 3.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PBP1_TM PF14812.6 KII89097.1 - 0.021 15.2 2.6 0.066 13.6 0.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RdRP PF05183.12 KII89098.1 - 2.3e-172 574.7 0.0 3.1e-172 574.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase PI3_PI4_kinase PF00454.27 KII89099.1 - 2.7e-35 122.4 0.1 7.9e-33 114.3 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KII89099.1 - 1.6e-23 83.0 0.1 5.1e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) GP41 PF00517.17 KII89099.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral envelope protein DUF4135 PF13575.6 KII89099.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Plavaka PF18759.1 KII89104.1 - 2.4e-126 421.4 0.0 3e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KII89104.1 - 0.68 10.9 4.5 0.25 12.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KII89104.1 - 5.2 7.7 7.5 0.32 11.5 0.5 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type FA_hydroxylase PF04116.13 KII89105.1 - 2.9e-23 82.7 18.2 2.9e-23 82.7 18.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 KII89107.1 - 4.2e-12 46.6 6.3 7e-12 45.8 6.3 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Far-17a_AIG1 PF04750.14 KII89107.1 - 0.017 14.5 1.6 0.024 13.9 1.6 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein FA_hydroxylase PF04116.13 KII89108.1 - 6.4e-09 36.3 7.8 6.9e-09 36.2 7.8 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Far-17a_AIG1 PF04750.14 KII89108.1 - 0.0047 16.3 2.6 0.0056 16.0 2.6 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Cytochrome_CBB3 PF13442.6 KII89112.1 - 0.034 14.5 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1657 PF07870.11 KII89112.1 - 0.042 13.7 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) CPDase PF07823.11 KII89116.1 - 3.1e-15 56.4 0.0 1e-14 54.7 0.0 1.9 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein DUF1776 PF08643.10 KII89116.1 - 3.5e-15 56.1 0.0 5.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2_5_RNA_ligase2 PF13563.6 KII89116.1 - 3e-05 24.0 0.2 0.00011 22.1 0.2 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF883 PF05957.13 KII89116.1 - 0.0014 19.2 0.1 0.13 12.9 0.2 2.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Taq-exonuc PF09281.10 KII89116.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Taq polymerase, exonuclease PRIMA1 PF16101.5 KII89116.1 - 2.9 7.9 9.4 0.41 10.7 0.6 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Brix PF04427.18 KII89118.1 - 5e-38 131.1 0.1 6.8e-38 130.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain DHHC PF01529.20 KII89119.1 - 2.3e-22 79.6 0.1 5.2e-18 65.4 1.4 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase SET PF00856.28 KII89120.1 - 1.8e-09 38.2 0.0 2.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KII89120.1 - 1.5e-06 28.2 16.0 3.2e-06 27.1 16.0 1.6 1 0 0 1 1 1 1 MYND finger IF-2B PF01008.17 KII89121.1 - 7.3e-63 212.4 0.1 8.8e-63 212.1 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family LepA_C PF06421.12 KII89122.1 - 6.4e-44 148.5 0.2 1.5e-43 147.3 0.2 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 KII89122.1 - 1.2e-39 135.9 0.2 2.8e-39 134.7 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KII89122.1 - 1.8e-17 63.1 0.0 3.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KII89122.1 - 4.4e-08 33.4 0.1 9.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KII89122.1 - 5.6e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KII89122.1 - 0.00017 21.6 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KII89122.1 - 0.00025 20.7 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KII89122.1 - 0.00033 20.5 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SIS_2 PF13580.6 KII89122.1 - 0.003 17.6 0.1 0.057 13.4 0.0 2.6 3 0 0 3 3 3 1 SIS domain RsgA_GTPase PF03193.16 KII89122.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.7 1 1 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KII89122.1 - 0.032 13.8 0.0 0.091 12.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KII89122.1 - 0.038 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KII89122.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain cwf18 PF08315.12 KII89123.1 - 7.5e-35 120.5 11.3 1e-34 120.1 11.3 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor LMWPc PF01451.21 KII89123.1 - 0.11 12.8 1.4 1.8 9.0 0.2 2.1 1 1 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF4407 PF14362.6 KII89123.1 - 0.83 8.9 5.4 0.87 8.9 5.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Gti1_Pac2 PF09729.9 KII89124.1 - 4.3e-30 105.2 0.2 1.5e-27 96.8 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Elongin_A PF06881.11 KII89125.1 - 1.3e-08 35.3 1.2 2.7e-08 34.3 1.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A FlhE PF06366.13 KII89127.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein FlhE Ecl1 PF12855.7 KII89128.1 - 0.0016 19.7 46.1 7.9e+02 1.1 44.9 2.9 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 KII89128.1 - 0.2 12.3 0.8 0.42 11.3 0.8 1.6 1 0 0 1 1 1 0 PLATZ transcription factor Vps54 PF07928.12 KII89130.1 - 5.4e-52 175.8 3.1 1.3e-51 174.5 3.1 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KII89130.1 - 4.7e-07 29.8 0.1 9.9e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KII89130.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex SepF PF04472.12 KII89130.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Cell division protein SepF GST_C_6 PF17171.4 KII89131.1 - 5e-14 51.8 0.0 1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII89131.1 - 0.00037 20.5 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 KII89131.1 - 0.0036 17.5 0.9 0.0072 16.6 0.9 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_N_4 PF17172.4 KII89131.1 - 0.004 17.9 0.0 0.0083 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain TRAM_LAG1_CLN8 PF03798.16 KII89132.1 - 9.4e-29 100.6 13.4 1.4e-28 100.0 13.4 1.3 1 0 0 1 1 1 1 TLC domain Ndc1_Nup PF09531.10 KII89132.1 - 0.42 9.2 3.1 0.6 8.7 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFCD_C PF12612.8 KII89133.1 - 0.087 12.6 0.6 0.22 11.3 0.1 2.0 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal G-gamma PF00631.22 KII89134.1 - 2.8e-24 84.9 0.0 3.2e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain COG5 PF10392.9 KII89134.1 - 0.12 12.5 0.4 0.15 12.3 0.4 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 G-gamma PF00631.22 KII89135.1 - 2.6e-17 62.6 1.8 2.4e-12 46.7 0.3 2.0 2 0 0 2 2 2 2 GGL domain Thioredoxin PF00085.20 KII89136.1 - 1.3e-21 76.5 0.0 1.6e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KII89136.1 - 2.6e-09 37.5 0.1 5.9e-09 36.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KII89136.1 - 1.8e-06 28.2 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KII89136.1 - 0.00039 20.5 0.0 0.00056 20.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KII89136.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KII89136.1 - 0.041 13.6 0.1 0.062 13.0 0.1 1.4 1 1 0 1 1 1 0 Redoxin ScsC_N PF18312.1 KII89136.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain OST3_OST6 PF04756.13 KII89136.1 - 0.096 12.0 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Cu_bind_like PF02298.17 KII89138.1 - 0.00012 22.0 0.5 0.00063 19.7 0.5 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 KII89138.1 - 0.019 15.4 0.2 0.034 14.6 0.2 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF442 PF04273.13 KII89138.1 - 0.022 14.9 0.0 0.049 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative phosphatase (DUF442) RAP1 PF07218.11 KII89138.1 - 0.79 7.9 6.2 0.98 7.6 6.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_capsid PF06112.11 KII89138.1 - 1.3 9.0 18.9 2.5 8.1 18.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AF-4 PF05110.13 KII89138.1 - 2.7 6.0 5.6 3.5 5.6 5.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein KH_1 PF00013.29 KII89139.1 - 1.2e-42 143.6 8.4 7.3e-15 54.5 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KII89139.1 - 5.7e-15 54.9 8.0 4.3e-05 23.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KII89139.1 - 1.3e-05 24.9 2.4 0.11 12.4 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KII89139.1 - 0.00044 20.3 5.4 0.94 9.6 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain Ebola_NP PF05505.12 KII89139.1 - 0.0023 16.4 0.3 0.003 15.9 0.3 1.1 1 0 0 1 1 1 1 Ebola nucleoprotein Sugar_tr PF00083.24 KII89140.1 - 2.8e-97 326.4 19.1 3.3e-97 326.2 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII89140.1 - 6.4e-35 120.7 41.0 5.4e-34 117.7 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KII89140.1 - 5.3e-08 31.6 6.7 1.9e-05 23.1 1.6 2.9 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_2 PF04550.12 KII89140.1 - 0.33 11.5 7.0 0.15 12.6 3.1 2.4 2 0 0 2 2 2 0 Phage holin family 2 Glyoxal_oxid_N PF07250.11 KII89141.1 - 9.6e-36 123.2 0.1 8.5e-35 120.1 0.1 2.4 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KII89141.1 - 2.5e-23 82.2 0.8 6.3e-23 80.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) CE2_N PF17996.1 KII89141.1 - 0.053 13.5 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal GATase_6 PF13522.6 KII89142.1 - 1.4e-13 51.2 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KII89142.1 - 2.7e-10 40.0 0.1 4.4e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 KII89142.1 - 1.6e-09 37.7 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KII89142.1 - 0.00037 19.5 0.0 0.00076 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Phosphonate-bd PF12974.7 KII89142.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein S-AdoMet_synt_C PF02773.16 KII89143.1 - 8e-68 226.7 0.4 2.2e-67 225.3 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KII89143.1 - 1.6e-46 157.5 0.0 2.9e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KII89143.1 - 2.7e-45 153.1 0.8 4.2e-45 152.5 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KII89143.1 - 0.026 13.3 0.3 0.16 10.7 0.1 2.0 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Myotub-related PF06602.14 KII89144.1 - 2.9e-150 500.1 0.1 3.5e-150 499.8 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain HTH_29 PF13551.6 KII89144.1 - 0.0088 16.0 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix DSPc PF00782.20 KII89144.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KII89144.1 - 0.077 13.0 0.0 0.33 10.9 0.0 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KII89144.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KII89145.1 - 2.5e-26 92.1 0.0 3.1e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII89145.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KII89145.1 - 0.085 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Phage_lysozyme2 PF18013.1 KII89145.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Phage tail lysozyme A_deaminase PF00962.22 KII89146.1 - 1.2e-28 100.4 0.0 5.4e-28 98.3 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KII89146.1 - 0.0091 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal COMP PF11598.8 KII89146.1 - 0.064 13.7 0.3 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Amidohydro_1 PF01979.20 KII89146.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase family Csm1 PF12539.8 KII89147.1 - 0.0094 16.6 0.3 0.039 14.6 0.3 2.0 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 PKcGMP_CC PF16808.5 KII89147.1 - 0.02 14.7 4.5 0.038 13.8 1.3 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TssC PF17541.2 KII89147.1 - 0.031 13.1 1.3 0.057 12.3 1.3 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Spc24 PF08286.11 KII89147.1 - 0.1 12.8 6.0 3.5 7.9 1.6 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DASH_Hsk3 PF08227.11 KII89147.1 - 0.34 11.3 4.3 1 9.7 0.7 2.7 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF812 PF05667.11 KII89147.1 - 1.1 8.1 15.9 1.4 7.7 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) EMP24_GP25L PF01105.24 KII89147.1 - 1.3 8.9 5.9 5.2 7.0 0.1 2.8 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD SHE3 PF17078.5 KII89147.1 - 2.9 7.5 11.7 19 4.9 11.7 2.1 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CDC37_N PF03234.14 KII89147.1 - 3.2 8.7 8.7 1.4 9.8 4.1 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Phage_GP20 PF06810.11 KII89147.1 - 4.1 7.2 11.5 0.96 9.2 3.1 2.8 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF5082 PF16888.5 KII89147.1 - 4.3 7.6 12.1 3.2 8.1 4.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 KII89147.1 - 5 7.3 10.0 2.3 8.4 3.8 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 KII89147.1 - 6 6.9 22.2 0.033 14.3 1.9 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Sec2p PF06428.11 KII89147.1 - 8.4 6.4 18.2 1.1 9.3 3.3 3.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Lzipper-MIP1 PF14389.6 KII89147.1 - 8.8 6.7 19.4 0.061 13.6 4.2 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Trp_syntA PF00290.20 KII89148.1 - 6.7e-84 280.8 0.3 1.1e-83 280.1 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KII89148.1 - 6.1e-46 157.2 0.3 1e-45 156.4 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 KII89148.1 - 3.8e-05 23.3 0.1 0.00011 21.8 0.1 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 KII89148.1 - 0.0022 17.4 0.1 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KII89148.1 - 0.043 13.1 0.2 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 KII89148.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase PcrB PF01884.17 KII89148.1 - 0.16 11.4 0.1 0.36 10.2 0.1 1.5 1 0 0 1 1 1 0 PcrB family KH_8 PF17903.1 KII89149.1 - 0.00017 21.6 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KII89149.1 - 0.0054 16.5 0.5 0.011 15.5 0.5 1.5 1 0 0 1 1 1 1 KH domain DUF3835 PF12927.7 KII89150.1 - 4.9e-07 30.5 0.9 4.9e-07 30.5 0.9 5.5 6 0 0 6 6 6 3 Domain of unknown function (DUF3835) Asparaginase PF00710.20 KII89151.1 - 1.8e-55 187.4 0.0 9.4e-55 185.1 0.0 2.1 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KII89151.1 - 1.1e-30 106.1 0.0 2e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KII89151.1 - 1e-12 48.5 0.1 7.4e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII89151.1 - 1.2e-11 44.9 0.0 6.2e-06 26.6 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII89151.1 - 6.7e-09 35.8 0.3 6.4e-08 32.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KII89151.1 - 9.4e-09 35.3 2.6 0.00027 21.2 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KII89151.1 - 6.4e-08 32.3 1.6 0.057 14.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat GATase_7 PF13537.6 KII89151.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glyco_transf_22 PF03901.17 KII89152.1 - 8.7e-85 285.5 20.3 1e-84 285.2 20.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1713 PF08213.11 KII89153.1 - 3.9e-10 39.5 23.3 5.9e-10 38.9 23.3 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) UQ_con PF00179.26 KII89155.1 - 1.4e-48 164.1 0.1 1.6e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII89155.1 - 0.046 14.0 0.6 0.084 13.2 0.6 1.6 1 1 0 1 1 1 0 RWD domain Ribosomal_L7Ae PF01248.26 KII89156.1 - 3.6e-25 87.5 0.0 4.7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KII89156.1 - 0.00038 20.5 0.0 0.00043 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KII89156.1 - 0.00039 20.2 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain Adenosine_kin PF04008.14 KII89156.1 - 0.03 14.1 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine specific kinase CDH-cyt PF16010.5 KII89157.1 - 5.1e-52 176.2 0.0 6e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Proteasome PF00227.26 KII89158.1 - 1.7e-49 167.9 0.1 2e-49 167.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FAD_binding_3 PF01494.19 KII89159.1 - 2.1e-51 175.2 0.0 4.7e-50 170.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KII89159.1 - 4e-06 26.3 0.1 0.0007 18.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII89159.1 - 5.4e-06 25.8 0.4 0.033 13.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII89159.1 - 1.4e-05 24.9 0.2 0.00076 19.2 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII89159.1 - 4.7e-05 23.9 0.3 0.11 13.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII89159.1 - 7.3e-05 21.6 0.5 0.19 10.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KII89159.1 - 0.0015 17.7 0.4 0.0022 17.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KII89159.1 - 0.0033 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_7 PF13241.6 KII89159.1 - 0.0072 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 KII89159.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 KII89159.1 - 0.046 13.9 0.3 0.11 12.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KII89159.1 - 0.066 13.3 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KII89159.1 - 0.08 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 KII89159.1 - 0.091 12.8 0.8 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 KII89159.1 - 0.16 11.2 0.9 0.88 8.8 0.6 2.0 1 1 1 2 2 2 0 Thi4 family Syja_N PF02383.18 KII89160.1 - 2.5e-92 309.6 0.0 3.3e-92 309.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KII89160.1 - 1.7e-30 105.1 0.0 3.2e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase zf-C2H2 PF00096.26 KII89161.1 - 6.3e-06 26.3 1.2 0.013 15.9 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII89161.1 - 6e-05 23.5 1.4 0.086 13.7 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII89161.1 - 0.0086 16.3 0.8 0.092 13.1 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KII89161.1 - 0.14 12.5 2.0 0.61 10.4 2.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 KII89161.1 - 0.24 11.8 1.6 6.5 7.2 2.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.7 KII89162.1 - 1.7e-06 28.8 0.2 1.7e-06 28.8 0.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII89162.1 - 0.00034 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KII89162.1 - 0.0007 19.5 0.2 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.12 KII89162.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) GFO_IDH_MocA PF01408.22 KII89163.1 - 5.7e-13 49.7 0.0 8.6e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold LIM PF00412.22 KII89164.1 - 8.2e-17 61.2 23.2 3.9e-11 43.0 6.4 3.9 4 0 0 4 4 4 3 LIM domain zf_UBZ PF18439.1 KII89164.1 - 0.43 10.2 0.0 0.43 10.2 0.0 4.6 5 1 1 6 6 6 0 Ubiquitin-Binding Zinc Finger DUF2321 PF10083.9 KII89164.1 - 3.1 7.4 6.7 1.4 8.5 3.9 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) AP_endonuc_2 PF01261.24 KII89165.1 - 2.3e-32 112.2 0.1 4.1e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mannitol_dh_C PF08125.13 KII89166.1 - 2.2e-44 151.8 0.0 3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KII89166.1 - 2.1e-18 67.0 0.0 4.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 KII89166.1 - 0.00099 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KII89166.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KII89166.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Caerin_1 PF07440.12 KII89166.1 - 0.26 11.4 1.4 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Caerin 1 protein ABC_tran PF00005.27 KII89167.1 - 4.3e-16 59.7 0.0 7.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KII89167.1 - 0.002 18.6 0.0 0.0051 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII89167.1 - 0.0036 17.6 0.0 0.0072 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KII89167.1 - 0.018 15.1 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII89167.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 KII89167.1 - 0.045 13.0 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KII89167.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII89167.1 - 0.082 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KII89167.1 - 0.098 12.0 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KII89167.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 KII89169.1 - 0.00035 20.8 0.0 0.0044 17.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain RPN7 PF10602.9 KII89170.1 - 2e-55 187.2 0.2 3.1e-55 186.6 0.2 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KII89170.1 - 7.7e-17 61.7 0.6 2.9e-16 59.9 0.0 2.3 3 1 0 3 3 3 1 PCI domain RPN6_N PF18055.1 KII89171.1 - 3.4e-46 156.4 2.1 3.4e-46 156.4 2.1 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KII89171.1 - 5.8e-18 65.3 1.1 9.7e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KII89171.1 - 4.6e-11 42.2 0.8 1.2e-10 40.9 0.8 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 KII89171.1 - 8.8e-05 22.3 3.6 0.03 14.4 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII89171.1 - 0.11 12.7 3.2 3.8 7.9 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KII89171.1 - 0.45 11.1 8.0 3.5 8.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HMGL-like PF00682.19 KII89173.1 - 5.9e-71 239.1 0.0 9.2e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KII89173.1 - 2e-46 157.2 0.1 5.9e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain tRNA-synt_1c PF00749.21 KII89174.1 - 1e-106 356.4 0.0 1.3e-106 356.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KII89174.1 - 3.5e-35 121.4 0.1 5.5e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KII89174.1 - 1.7e-06 28.0 0.1 5.2e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII89174.1 - 4.9e-06 26.7 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII89174.1 - 0.00011 22.3 0.0 0.00067 19.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KII89174.1 - 0.055 12.8 0.2 0.13 11.6 0.1 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain HLH PF00010.26 KII89175.1 - 1.2e-11 44.4 0.7 2.2e-11 43.5 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain APG9 PF04109.16 KII89178.1 - 7e-211 701.4 2.8 8.1e-211 701.1 2.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 EF-hand_4 PF12763.7 KII89179.1 - 7e-06 25.9 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3827 PF12877.7 KII89179.1 - 0.68 8.2 4.0 1.3 7.3 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Thiamine_BP PF01910.17 KII89180.1 - 1.1e-26 92.6 0.0 1.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 KII89180.1 - 7.8e-05 23.1 0.0 9.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DNA_methylase PF00145.17 KII89181.1 - 3.5e-48 164.7 0.0 4.9e-34 118.2 0.0 2.9 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 KII89181.1 - 7.7e-12 45.1 0.0 2.8e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KII89181.1 - 2.2e-09 37.5 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BaffR-Tall_bind PF09256.10 KII89181.1 - 0.083 12.7 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Vps36-NZF-N PF16988.5 KII89181.1 - 0.098 12.1 0.1 6.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain MCM PF00493.23 KII89182.1 - 7.2e-105 349.0 0.0 2.1e-104 347.5 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KII89182.1 - 8e-30 103.3 0.1 1.3e-29 102.6 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KII89182.1 - 1.5e-19 70.5 2.7 1.9e-19 70.2 1.3 2.0 2 0 0 2 2 1 1 MCM N-terminal domain MCM_lid PF17855.1 KII89182.1 - 1.9e-19 69.8 0.9 4.8e-19 68.6 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KII89182.1 - 6.5e-08 32.2 0.1 9.7e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KII89182.1 - 7.7e-08 32.4 0.0 9e-07 29.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KII89182.1 - 0.003 18.2 1.2 0.0065 17.1 0.4 2.0 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal PI-TkoII_IV PF18714.1 KII89182.1 - 0.013 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV AAA_3 PF07726.11 KII89182.1 - 0.023 14.6 0.0 0.073 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 KII89182.1 - 0.045 13.6 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 KII89182.1 - 0.073 12.8 0.1 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 KII89182.1 - 0.48 10.8 3.1 2.9 8.3 0.0 3.0 3 1 1 4 4 4 0 AAA ATPase domain Peptidase_S8 PF00082.22 KII89183.1 - 1.7e-31 109.6 0.8 2.4e-31 109.1 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KII89183.1 - 6.5e-26 90.2 0.1 1.1e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain SKG6 PF08693.10 KII89183.1 - 2.6 7.5 4.5 6.4 6.3 4.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain POT1PC PF16686.5 KII89184.1 - 1.3e-23 83.6 0.0 6.3e-10 39.1 0.0 4.3 3 2 0 3 3 3 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KII89184.1 - 8.9e-14 51.5 0.0 2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 KII89185.1 - 2.9e-10 40.2 0.1 2.5e-08 33.9 0.7 2.6 2 1 0 2 2 2 1 ssDNA-binding domain of telomere protection protein TAP42 PF04177.12 KII89186.1 - 8.7e-91 304.4 0.7 9.9e-91 304.2 0.7 1.0 1 0 0 1 1 1 1 TAP42-like family Cwf_Cwc_15 PF04889.12 KII89186.1 - 2 8.1 8.9 0.27 11.0 4.2 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 KII89187.1 - 2e-59 199.8 0.3 2.5e-59 199.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89187.1 - 1.9e-37 128.1 0.1 3.2e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII89187.1 - 3.3e-16 59.2 0.1 4.1e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KII89187.1 - 6.8e-07 28.9 0.1 1.1e-06 28.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KII89187.1 - 2e-06 27.5 0.4 2.1e-05 24.1 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KII89187.1 - 7.2e-06 25.5 0.6 9.4e-06 25.1 0.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII89187.1 - 9.1e-06 25.7 0.1 5.1e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII89187.1 - 7.9e-05 22.6 0.1 0.02 14.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KII89187.1 - 0.0031 17.0 0.6 0.18 11.3 0.6 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KII89187.1 - 0.042 13.9 0.0 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Dynamin family TniB PF05621.11 KII89187.1 - 0.048 13.1 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein CPT PF07931.12 KII89187.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 KII89187.1 - 0.068 12.9 1.6 0.38 10.5 1.6 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KII89187.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MTHFR PF02219.17 KII89188.1 - 8.1e-103 343.7 0.0 1.2e-102 343.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Na_trans_assoc PF06512.13 KII89189.1 - 0.011 16.1 6.1 0.012 15.9 6.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated ANAPC15 PF15243.6 KII89189.1 - 3.1 8.2 25.9 0.61 10.5 15.1 3.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 WD40 PF00400.32 KII89190.1 - 1.1e-09 38.7 10.0 0.004 18.0 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89190.1 - 9.9e-06 25.8 0.0 0.077 13.3 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KII89190.1 - 0.0027 16.3 0.0 0.014 14.0 0.0 1.9 1 1 1 2 2 2 2 Cytochrome D1 heme domain Transket_pyr PF02779.24 KII89191.1 - 4e-40 137.4 0.0 5.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KII89191.1 - 2.1e-28 98.7 0.0 9.1e-28 96.6 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain Peptidase_C1_2 PF03051.15 KII89191.1 - 0.18 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Peptidase_S28 PF05577.12 KII89193.1 - 7.1e-57 193.1 0.0 4.3e-45 154.3 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 CPBP PF02517.16 KII89194.1 - 8.6e-16 58.1 4.0 2.6e-15 56.5 3.8 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF543 PF04418.12 KII89194.1 - 0.27 11.3 1.4 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ATP-synt_ab PF00006.25 KII89195.1 - 8.5e-64 215.1 0.0 1.3e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KII89195.1 - 2.6e-21 75.9 2.7 2.6e-21 75.9 2.7 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KII89195.1 - 0.0064 15.7 0.8 0.012 14.8 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 KII89195.1 - 0.021 14.7 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 KII89195.1 - 0.027 14.9 0.0 0.31 11.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KII89195.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KII89195.1 - 0.051 14.0 0.2 0.17 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KII89195.1 - 0.068 12.5 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KII89195.1 - 0.068 13.5 1.0 0.3 11.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII89195.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Pyr_redox_2 PF07992.14 KII89196.1 - 7.7e-45 153.4 0.0 1.1e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KII89196.1 - 7.4e-10 37.7 1.3 9.5e-05 21.7 0.3 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 KII89196.1 - 9.9e-10 38.8 0.0 9.5e-06 26.1 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 KII89196.1 - 2.1e-09 36.5 1.0 0.00011 21.8 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KII89196.1 - 1.9e-07 31.4 1.0 0.00084 19.8 0.0 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KII89196.1 - 1.5e-05 24.8 1.8 0.083 12.8 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KII89196.1 - 5.5e-05 22.5 0.6 0.019 14.5 0.2 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.6 KII89196.1 - 0.007 15.6 2.7 0.59 9.3 2.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KII89196.1 - 0.012 16.0 0.1 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KII89196.1 - 0.036 14.3 0.0 0.94 9.8 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CLP1_N PF16573.5 KII89197.1 - 5.1e-35 119.6 0.0 7.9e-35 119.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KII89197.1 - 1.9e-33 115.9 0.0 4.1e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KII89197.1 - 1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 Acetyltransf_18 PF18014.1 KII89197.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_16 PF13191.6 KII89197.1 - 0.19 12.1 0.0 0.51 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KII89197.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KII89197.1 - 0.25 10.7 0.0 2.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MFS_1 PF07690.16 KII89198.1 - 5.5e-26 91.3 30.6 5.5e-26 91.3 30.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII89198.1 - 0.00084 18.7 5.4 0.00084 18.7 5.4 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CDP-OH_P_tran_2 PF08009.11 KII89198.1 - 0.57 10.1 7.2 3.9 7.4 0.9 3.7 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 Pkinase PF00069.25 KII89199.1 - 3.6e-66 223.2 0.1 6.6e-66 222.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89199.1 - 3.9e-36 124.7 0.0 5.2e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII89199.1 - 1.8e-08 34.0 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII89199.1 - 5.7e-05 22.1 0.0 9.4e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII89199.1 - 0.0013 18.7 1.1 0.0021 18.0 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII89199.1 - 0.027 13.4 0.3 0.044 12.7 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KII89199.1 - 0.04 13.3 0.6 0.096 12.0 0.6 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KII89199.1 - 0.071 12.7 0.3 18 4.9 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KII89199.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA PF00004.29 KII89200.1 - 3.5e-12 46.9 0.0 7.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KII89200.1 - 1.9e-05 24.6 0.1 0.00016 21.6 0.0 2.2 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 KII89200.1 - 0.00026 21.4 0.2 0.0037 17.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KII89200.1 - 0.00034 20.4 0.0 0.00089 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KII89200.1 - 0.00068 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KII89200.1 - 0.002 18.4 0.1 0.04 14.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KII89200.1 - 0.0045 17.1 0.2 0.022 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII89200.1 - 0.0062 16.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KII89200.1 - 0.0089 16.0 0.1 0.041 13.8 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_assoc_2 PF16193.5 KII89200.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 KII89200.1 - 0.087 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KII89200.1 - 0.089 13.3 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KII89200.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KII89200.1 - 0.11 11.6 0.0 0.61 9.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein dNK PF01712.19 KII89200.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_30 PF13604.6 KII89200.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KII89200.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 KII89200.1 - 0.13 11.9 0.1 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_2 PF07724.14 KII89200.1 - 0.17 12.0 0.1 0.43 10.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KII89200.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Aminotran_1_2 PF00155.21 KII89201.1 - 1.7e-12 47.2 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II HSP70 PF00012.20 KII89202.1 - 1.1e-263 875.9 6.5 1.3e-263 875.7 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KII89202.1 - 6.8e-15 54.7 0.0 1.1e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KII89202.1 - 0.00079 19.2 0.0 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain VSG_B PF13206.6 KII89202.1 - 0.012 14.9 0.3 0.028 13.7 0.2 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain Hydantoinase_A PF01968.18 KII89202.1 - 0.038 13.2 0.2 0.12 11.6 0.2 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Raco_middle PF17651.1 KII89202.1 - 0.064 12.9 0.0 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 RACo middle region B56 PF01603.20 KII89203.1 - 3.1e-193 642.4 4.0 3.6e-193 642.2 4.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SPX PF03105.19 KII89203.1 - 2.5 7.9 6.8 4.1 7.2 6.8 1.3 1 0 0 1 1 1 0 SPX domain TMEM171 PF15471.6 KII89203.1 - 9 5.2 8.0 18 4.2 8.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Citrate_synt PF00285.21 KII89205.1 - 1.3e-97 327.1 0.0 1.7e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain XH PF03469.14 KII89205.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 XH domain Sec66 PF09802.9 KII89206.1 - 3.7e-58 196.1 0.0 4.6e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SieB PF14163.6 KII89206.1 - 0.12 11.9 0.2 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Super-infection exclusion protein B USP7_ICP0_bdg PF12436.8 KII89207.1 - 2.9e-86 288.7 0.1 1e-83 280.3 0.0 3.2 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KII89207.1 - 4.2e-67 225.9 4.9 1e-63 214.8 0.2 3.5 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KII89207.1 - 5.1e-50 170.4 0.1 7.8e-50 169.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII89207.1 - 1.2e-20 74.4 0.0 4.5e-20 72.5 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KII89207.1 - 3.8e-07 30.3 0.0 1.8e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 KII89207.1 - 0.0074 16.0 0.1 0.35 10.6 0.0 3.6 4 0 0 4 4 4 1 Ubiquitin family Cys_rich_VLP PF14194.6 KII89207.1 - 0.21 11.7 0.1 0.55 10.4 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Methyltr_RsmB-F PF01189.17 KII89210.1 - 2.2e-76 256.0 0.0 3e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KII89210.1 - 8.4e-08 32.6 0.0 2.5e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KII89210.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KII89210.1 - 0.0027 17.5 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KII89210.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 KII89210.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KII89210.1 - 0.051 14.3 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.12 KII89211.1 - 1.1e-21 77.4 15.1 1.5e-21 77.0 15.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Abhydrolase_9_N PF15420.6 KII89211.1 - 0.079 12.9 6.2 0.17 11.9 6.2 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF1689 PF07954.11 KII89211.1 - 0.25 11.7 0.2 0.39 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) NADH_dh_m_C1 PF15088.6 KII89211.1 - 0.33 10.6 2.5 0.93 9.2 2.5 1.7 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial PI3K_1B_p101 PF10486.9 KII89212.1 - 0.72 7.6 4.1 1.1 7.0 4.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hydrolase_4 PF12146.8 KII89213.1 - 1.9e-46 158.3 0.0 2.3e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII89213.1 - 7.4e-12 46.3 0.2 9.4e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII89213.1 - 1.1e-05 25.2 0.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KII89213.1 - 0.00044 19.0 0.1 0.0078 14.9 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 KII89213.1 - 0.044 13.3 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KII89213.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Asn_synthase PF00733.21 KII89214.1 - 1.3e-93 314.5 0.1 4.9e-56 190.9 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KII89214.1 - 1e-35 122.3 0.0 1.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KII89214.1 - 2.4e-29 102.2 0.0 4.6e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KII89214.1 - 0.00036 20.1 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KII89214.1 - 0.0075 15.4 0.0 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 NAD synthase QueC PF06508.13 KII89214.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC RhoGEF PF00621.20 KII89215.1 - 6.9e-19 68.8 0.1 4.2e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.9 KII89216.1 - 3.6e-18 65.9 0.0 1e-12 48.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase EF_assoc_2 PF08356.12 KII89217.1 - 0.00033 20.6 0.1 0.00054 19.9 0.1 1.3 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KII89217.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 EF hand associated EF-hand_8 PF13833.6 KII89217.1 - 0.065 13.1 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 KII89217.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DEAD PF00270.29 KII89218.1 - 9.1e-47 159.1 0.0 3.2e-46 157.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII89218.1 - 3.4e-29 101.4 0.0 1.4e-28 99.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII89218.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEM4 PF02602.15 KII89218.1 - 0.014 14.7 0.5 0.027 13.8 0.5 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD DUF3334 PF11813.8 KII89218.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) CDP-OH_P_transf PF01066.21 KII89219.1 - 4.9e-12 46.4 1.1 1.2e-11 45.2 0.6 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3176 PF11374.8 KII89220.1 - 0.32 11.2 4.1 0.55 10.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) HSA PF07529.13 KII89221.1 - 5.1e-13 49.1 0.1 5.1e-13 49.1 0.1 3.5 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 KII89221.1 - 1.8e-08 34.5 0.6 6.6e-08 32.7 0.6 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KII89221.1 - 3.5e-05 23.9 0.5 0.00014 22.0 0.5 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ODV-E18 PF10717.9 KII89222.1 - 0.083 12.8 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HicB-like_2 PF15970.5 KII89222.1 - 0.1 12.8 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system Cellulase PF00150.18 KII89223.1 - 2.1e-09 37.2 0.0 4.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KII89223.1 - 0.025 14.5 4.5 1.1 9.3 0.5 2.7 2 0 0 2 2 2 0 Fungal cellulose binding domain IATP PF04568.12 KII89224.1 - 0.00034 21.0 0.6 0.00042 20.7 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Ribonuclease_T2 PF00445.18 KII89225.1 - 6.7e-37 127.5 0.3 9.5e-37 127.0 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Aldedh PF00171.22 KII89226.1 - 2.1e-120 402.4 0.0 2.4e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cupredoxin_1 PF13473.6 KII89230.1 - 8.8e-05 22.6 0.1 0.033 14.3 0.1 2.6 2 0 0 2 2 2 2 Cupredoxin-like domain Copper-bind PF00127.20 KII89230.1 - 0.00011 22.5 1.6 0.22 12.0 0.1 2.7 2 1 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KII89230.1 - 0.00031 20.7 6.9 0.18 11.8 0.2 3.7 2 2 0 2 2 2 2 Plastocyanin-like domain CusF_Ec PF11604.8 KII89230.1 - 0.013 15.5 0.9 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Copper binding periplasmic protein CusF DUF4501 PF14946.6 KII89230.1 - 0.067 13.3 4.5 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) MUG113 PF13455.6 KII89231.1 - 2.2e-13 50.7 0.0 6.7e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KII89231.1 - 1.8e-07 31.6 0.0 1.6e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 T5orf172 domain Sas10_Utp3 PF04000.15 KII89232.1 - 7.1e-11 42.6 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family UDG PF03167.19 KII89233.1 - 1.2e-18 67.6 0.0 1.7e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Prefoldin_2 PF01920.20 KII89234.1 - 0.01 15.8 0.4 0.017 15.0 0.4 1.3 1 0 0 1 1 1 0 Prefoldin subunit HMMR_C PF15908.5 KII89234.1 - 0.053 13.8 0.1 0.079 13.2 0.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal ERM PF00769.19 KII89234.1 - 0.063 13.1 3.5 0.1 12.4 3.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAUS6_N PF14661.6 KII89234.1 - 0.068 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ABC_tran_CTD PF16326.5 KII89234.1 - 0.08 13.2 3.0 0.14 12.4 3.0 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF4337 PF14235.6 KII89234.1 - 0.12 12.4 0.4 0.19 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Prefoldin PF02996.17 KII89234.1 - 0.32 10.9 1.1 0.52 10.2 1.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit GrpE PF01025.19 KII89234.1 - 6.3 6.4 6.8 0.75 9.4 2.7 1.4 2 0 0 2 2 2 0 GrpE dsDNA_bind PF01984.20 KII89236.1 - 1.2e-26 93.2 10.7 1.4e-26 92.9 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain baeRF_family12 PF18856.1 KII89236.1 - 0.061 13.9 1.2 0.085 13.4 0.6 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 Spore_III_AF PF09581.10 KII89236.1 - 0.13 12.3 1.3 0.16 12.0 1.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DIM PF08194.12 KII89237.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 DIM protein EutK_C PF16365.5 KII89237.1 - 0.063 13.3 0.1 0.46 10.5 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus UCH_1 PF13423.6 KII89238.1 - 1.6e-89 300.7 0.1 2.2e-89 300.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KII89238.1 - 4.5e-20 72.9 0.0 7.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease FMO-like PF00743.19 KII89239.1 - 2.2e-40 138.6 0.0 6.7e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII89239.1 - 2e-17 63.4 0.0 2.4e-13 50.0 0.0 3.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII89239.1 - 2.8e-10 39.9 0.0 1.5e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII89239.1 - 5.2e-09 35.7 0.0 1.9e-07 30.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KII89239.1 - 2e-06 27.9 0.0 0.00062 20.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII89239.1 - 8.2e-06 25.6 0.1 1 8.8 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII89239.1 - 2.4e-05 24.4 0.0 0.00054 20.0 0.0 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KII89239.1 - 0.001 18.4 0.1 0.41 9.8 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 KII89239.1 - 0.0053 17.3 0.4 0.55 10.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KII89239.1 - 0.0054 17.1 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KII89239.1 - 0.0063 15.8 0.0 0.39 9.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KII89239.1 - 0.0078 16.3 0.2 0.3 11.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KII89239.1 - 0.037 12.7 0.3 0.88 8.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KII89239.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KII89239.1 - 0.22 10.6 0.2 5.2 6.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DUF2618 PF10940.8 KII89240.1 - 0.0025 17.6 1.9 0.0037 17.0 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2618) CBFD_NFYB_HMF PF00808.23 KII89242.1 - 1e-20 73.8 1.0 1.4e-20 73.4 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII89242.1 - 2.7e-12 47.2 0.1 4.2e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KII89242.1 - 0.031 14.6 0.1 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TAF PF02969.17 KII89242.1 - 0.12 12.6 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) F-box-like PF12937.7 KII89243.1 - 0.00037 20.3 1.4 0.0007 19.4 0.7 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 KII89243.1 - 3.2 7.6 6.3 12 5.8 0.1 4.4 5 0 0 5 5 5 0 Leucine rich repeat CENP-F_leu_zip PF10473.9 KII89244.1 - 0.012 15.7 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3287 PF11690.8 KII89244.1 - 0.031 14.0 0.9 3.8 7.3 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) zf-RING_4 PF14570.6 KII89246.1 - 1.6e-21 75.8 10.9 2.6e-21 75.1 10.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KII89246.1 - 2.9e-05 23.8 8.8 5e-05 23.1 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KII89246.1 - 0.0033 17.2 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 KII89246.1 - 0.008 16.0 8.5 0.47 10.4 9.3 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KII89246.1 - 0.031 14.6 11.6 0.057 13.8 11.6 1.4 1 0 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.11 KII89246.1 - 0.045 13.7 3.5 0.086 12.8 3.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 KII89246.1 - 0.2 11.8 2.6 0.5 10.5 2.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 KII89246.1 - 1.2 9.2 7.2 2.1 8.4 6.0 2.0 1 1 1 2 2 2 0 RING-type zinc-finger DUF1272 PF06906.11 KII89246.1 - 2.9 8.1 7.5 5.6 7.1 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Cupin_8 PF13621.6 KII89247.1 - 4.1e-32 111.9 0.0 5.5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KII89247.1 - 2.6e-05 23.9 0.0 4.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 KII89247.1 - 0.0026 18.2 0.0 0.0079 16.6 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 KII89247.1 - 0.004 16.8 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KII89247.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KII89247.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3535 PF12054.8 KII89248.1 - 6.2e-101 338.8 4.6 1.3e-100 337.7 0.7 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KII89248.1 - 9.6e-68 228.4 0.0 1.8e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII89248.1 - 1.4e-16 60.8 0.0 3.9e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KII89248.1 - 1.5e-12 46.6 11.6 1.9 9.0 0.0 10.0 10 0 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.6 KII89248.1 - 0.00011 22.6 12.6 11 6.6 0.1 8.2 8 1 0 8 8 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KII89248.1 - 0.00027 21.5 0.1 1.7 9.3 0.0 3.4 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KII89248.1 - 0.0003 20.7 0.2 0.0015 18.5 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) ResIII PF04851.15 KII89248.1 - 0.00033 20.7 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HEAT_2 PF13646.6 KII89248.1 - 0.0013 19.0 10.2 3.2 8.2 0.0 6.8 6 1 0 6 6 6 1 HEAT repeats TAF6_C PF07571.13 KII89248.1 - 0.0056 17.0 1.0 0.64 10.4 0.0 4.3 6 0 0 6 6 5 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KII89248.1 - 0.051 13.1 0.0 1.5 8.3 0.1 3.1 2 1 0 2 2 2 0 CLASP N terminal Dopey_N PF04118.14 KII89248.1 - 0.085 12.0 0.1 0.2 10.7 0.1 1.6 1 0 0 1 1 1 0 Dopey, N-terminal ERCC3_RAD25_C PF16203.5 KII89248.1 - 0.098 11.8 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase GPI-anchored PF10342.9 KII89249.1 - 0.00072 20.3 2.1 0.00072 20.3 2.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CoA_trans PF01144.23 KII89250.1 - 1.6e-102 341.5 4.7 2.2e-62 210.3 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KII89250.1 - 0.0003 20.8 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KII89250.1 - 0.024 14.6 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain Mal_decarbox_Al PF16957.5 KII89250.1 - 0.098 11.0 0.1 0.19 10.0 0.1 1.4 1 1 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter SMI1_KNR4 PF09346.10 KII89251.1 - 1.2e-20 74.3 0.0 2.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SOG2 PF10428.9 KII89252.1 - 2.2e-93 314.2 2.3 2.2e-93 314.2 2.3 3.1 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 KII89252.1 - 3.5e-12 45.9 7.5 7.1e-07 28.9 1.1 3.3 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KII89252.1 - 1e-09 38.5 4.0 1.6e-06 28.4 1.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII89252.1 - 0.0019 18.5 4.8 8.6 7.3 0.1 4.9 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 KII89252.1 - 0.034 13.7 1.6 0.057 12.9 1.2 1.5 2 0 0 2 2 2 0 Leucine-rich repeat CoA_trans PF01144.23 KII89253.1 - 4.8e-103 343.2 2.7 8.7e-61 205.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KII89253.1 - 0.00023 21.1 0.1 0.00051 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KII89253.1 - 0.0037 15.7 0.1 0.0074 14.7 0.1 1.4 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter Cofilin_ADF PF00241.20 KII89254.1 - 1e-30 106.0 0.0 5.1e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein FYVE PF01363.21 KII89255.1 - 1.8e-17 63.2 1.3 3.1e-17 62.5 1.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KII89255.1 - 1.4e-16 59.9 0.8 6.3e-16 57.8 0.8 2.2 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 KII89255.1 - 0.008 16.1 6.2 0.008 16.1 6.2 2.0 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type Occludin_ELL PF07303.13 KII89255.1 - 0.014 16.1 2.5 0.017 15.9 0.4 2.0 2 0 0 2 2 2 0 Occludin homology domain FYVE_2 PF02318.16 KII89255.1 - 0.031 14.5 1.8 0.041 14.1 0.5 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger FAP PF07174.11 KII89255.1 - 0.57 9.6 0.0 0.57 9.6 0.0 3.0 3 0 0 3 3 3 0 Fibronectin-attachment protein (FAP) zf-C3HC4_3 PF13920.6 KII89256.1 - 2.4e-05 24.1 12.6 5.1e-05 23.0 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII89256.1 - 0.00015 22.0 13.5 0.00031 21.0 13.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII89256.1 - 0.00057 19.7 12.1 0.03 14.2 13.8 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KII89256.1 - 0.0009 19.2 13.7 0.0018 18.2 13.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII89256.1 - 0.00092 19.0 13.5 0.0018 18.1 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BST2 PF16716.5 KII89256.1 - 0.0053 17.3 6.2 0.0053 17.3 6.2 4.0 3 1 0 3 3 3 2 Bone marrow stromal antigen 2 GIT_CC PF16559.5 KII89256.1 - 0.0057 16.5 6.3 0.017 14.9 0.1 3.5 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Tropomyosin_1 PF12718.7 KII89256.1 - 0.0074 16.4 22.3 0.019 15.1 6.2 3.0 2 1 0 2 2 2 2 Tropomyosin like zf-C3HC4 PF00097.25 KII89256.1 - 0.0083 16.0 11.8 0.018 14.9 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.21 KII89256.1 - 0.011 15.8 5.9 0.34 11.0 0.6 4.6 4 0 0 4 4 4 0 bZIP transcription factor PRKG1_interact PF15898.5 KII89256.1 - 0.011 16.6 4.2 0.011 16.6 4.2 3.9 3 1 1 4 4 4 0 cGMP-dependent protein kinase interacting domain SOGA PF11365.8 KII89256.1 - 0.032 15.3 16.3 2.6 9.2 2.8 4.1 3 2 0 3 3 3 0 Protein SOGA TPR_MLP1_2 PF07926.12 KII89256.1 - 0.035 14.2 36.9 1.7 8.7 13.7 4.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-RING_4 PF14570.6 KII89256.1 - 0.16 11.8 10.8 0.34 10.8 10.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0160 PF03690.13 KII89256.1 - 0.41 10.3 4.8 0.27 10.8 1.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0160) YabA PF06156.13 KII89256.1 - 0.61 10.7 10.7 19 5.9 0.1 4.4 3 2 1 4 4 4 0 Initiation control protein YabA HCMV_UL139 PF12507.8 KII89256.1 - 0.81 10.1 14.0 0.63 10.4 3.8 3.8 2 2 1 3 3 3 0 Human Cytomegalovirus UL139 protein zf-RING_6 PF14835.6 KII89256.1 - 0.94 9.4 10.0 2.4 8.1 10.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TSC22 PF01166.18 KII89256.1 - 1.4 9.3 8.4 46 4.4 0.4 4.8 5 0 0 5 5 5 0 TSC-22/dip/bun family Fez1 PF06818.15 KII89256.1 - 2 8.8 32.6 0.85 10.0 5.4 3.6 2 1 2 4 4 4 0 Fez1 DUF4472 PF14739.6 KII89256.1 - 2.2 9.1 23.1 1.4 9.7 3.2 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4472) Jnk-SapK_ap_N PF09744.9 KII89256.1 - 2.5 8.3 32.8 0.26 11.5 5.6 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 KII89256.1 - 2.8 8.1 11.8 0.58 10.3 0.3 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family zf-RING_UBOX PF13445.6 KII89256.1 - 3.1 7.9 13.4 7.2 6.7 13.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Lebercilin PF15619.6 KII89256.1 - 4.6 6.9 28.5 0.46 10.1 5.1 3.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 KII89256.1 - 4.9 7.2 13.5 7.7 6.6 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 KII89256.1 - 5.7 6.7 13.7 8.2 6.2 0.7 4.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.9 KII89256.1 - 7.1 6.7 24.4 0.32 11.0 1.8 4.3 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KII89256.1 - 7.5 6.8 30.2 0.16 12.2 3.1 4.1 4 1 1 5 5 4 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KII89256.1 - 7.5 7.2 22.6 5.8 7.6 0.7 6.2 4 2 1 6 6 6 0 SlyX APG6_N PF17675.1 KII89256.1 - 7.8 7.0 30.2 13 6.3 3.1 3.7 2 1 0 2 2 1 0 Apg6 coiled-coil region RasGAP_C PF03836.15 KII89256.1 - 9.3 6.4 9.2 5.1 7.3 0.6 3.5 3 1 0 3 3 3 0 RasGAP C-terminus Glyco_hydro_88 PF07470.13 KII89257.1 - 6.5e-11 41.9 0.0 9.5e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 TBP PF00352.21 KII89258.1 - 5.2e-67 221.8 0.2 1.1e-32 111.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KII89258.1 - 3.7e-05 23.8 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KII89258.1 - 0.045 13.6 0.0 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Spt20 PF12090.8 KII89262.1 - 0.04 13.5 14.7 0.053 13.1 14.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF908 PF06012.12 KII89262.1 - 6.5 6.1 9.9 8.2 5.7 9.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TBP PF00352.21 KII89263.1 - 5.9e-49 164.0 0.2 5e-32 109.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KII89263.1 - 0.00017 21.6 0.0 0.52 10.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) tRNA-synt_1b PF00579.25 KII89264.1 - 8.8e-19 67.9 0.0 4.1e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-C3HC4_2 PF13923.6 KII89265.1 - 1.7e-09 37.4 9.1 1.7e-09 37.4 9.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII89265.1 - 1e-08 35.2 8.6 1e-08 35.2 8.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 KII89265.1 - 1.2e-08 34.7 9.6 1.2e-08 34.7 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII89265.1 - 1.1e-07 31.7 4.1 1.1e-07 31.7 4.1 2.6 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KII89265.1 - 1.8e-07 30.9 2.4 1.8e-07 30.9 2.4 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KII89265.1 - 9e-07 28.7 7.0 9e-07 28.7 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII89265.1 - 1.9e-06 27.7 8.8 1.9e-06 27.7 8.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII89265.1 - 3.6e-06 27.2 8.7 3.6e-06 27.2 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.15 KII89265.1 - 0.00011 22.3 0.0 0.00036 20.7 0.0 1.9 2 0 0 2 2 1 1 U-box domain Prok-RING_4 PF14447.6 KII89265.1 - 0.00063 19.6 13.2 0.017 14.9 8.2 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KII89265.1 - 0.00066 19.8 5.9 0.00066 19.8 5.9 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KII89265.1 - 0.0067 16.7 7.4 0.0067 16.7 7.4 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KII89265.1 - 0.034 13.9 1.8 0.034 13.9 1.8 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KII89265.1 - 0.36 10.7 9.5 0.039 13.8 4.5 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 KII89265.1 - 0.42 10.7 6.7 1.4 9.0 2.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KII89265.1 - 0.61 10.1 7.5 0.29 11.1 3.6 2.2 2 0 0 2 2 2 0 zinc-ribbons DUF4451 PF14616.6 KII89265.1 - 1 9.6 4.4 5.7 7.2 2.3 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) zf-Di19 PF05605.12 KII89265.1 - 2.5 8.5 12.1 1.4 9.3 0.2 2.8 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding DUF1272 PF06906.11 KII89265.1 - 6.2 7.0 7.9 1.6 8.9 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) NTF2 PF02136.20 KII89267.1 - 1.4e-33 116.0 0.1 1.6e-33 115.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain S1-P1_nuclease PF02265.16 KII89268.1 - 6.4e-60 203.1 0.0 4.1e-58 197.2 0.0 2.0 1 1 0 1 1 1 1 S1/P1 Nuclease DUF1534 PF07551.11 KII89269.1 - 0.035 13.8 0.1 0.061 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) Dynamin_M PF01031.20 KII89271.1 - 4.2e-102 341.2 0.6 1.3e-101 339.6 0.0 2.0 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KII89271.1 - 1e-54 185.1 0.0 1.9e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KII89271.1 - 6.8e-29 99.9 3.2 1.7e-28 98.6 3.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII89271.1 - 0.0002 21.4 0.0 0.0013 18.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Lysine_decarbox PF03641.14 KII89272.1 - 3e-32 111.5 0.0 4.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KII89272.1 - 5.6e-08 32.5 3.7 1.1e-07 31.6 3.6 1.5 1 1 0 1 1 1 1 SLOG cluster4 family DUF659 PF04937.15 KII89273.1 - 8e-15 55.0 0.1 1.4e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KII89273.1 - 0.0022 17.8 0.0 0.0077 16.0 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Rib_recp_KP_reg PF05104.12 KII89273.1 - 0.12 13.4 1.8 0.28 12.2 1.8 1.6 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region F-box-like PF12937.7 KII89274.1 - 7.9e-07 28.9 0.9 2.2e-06 27.5 0.9 1.8 1 0 0 1 1 1 1 F-box-like Cullin_binding PF03556.15 KII89276.1 - 4.2e-25 88.5 0.1 1.1e-24 87.1 0.1 1.7 2 0 0 2 2 2 1 Cullin binding Ndc1_Nup PF09531.10 KII89276.1 - 4.4 5.9 4.7 5.2 5.6 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FeS_assembly_P PF01883.19 KII89277.1 - 6.4e-13 48.7 0.2 1.2e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein OCD_Mu_crystall PF02423.15 KII89278.1 - 2.6e-28 98.9 0.4 2.4e-21 76.0 0.1 3.2 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family ADH_zinc_N PF00107.26 KII89279.1 - 1.9e-06 27.9 0.2 4.5e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII89279.1 - 0.038 15.0 0.2 0.1 13.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII89280.1 - 1.7e-24 87.4 0.1 4.3e-24 86.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89280.1 - 2e-15 56.9 0.2 5.1e-15 55.6 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89280.1 - 0.0021 17.9 0.0 0.023 14.6 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KII89280.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Hat1_N PF10394.9 KII89281.1 - 4.7e-53 179.7 0.0 9.7e-53 178.7 0.0 1.5 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KII89281.1 - 3.5e-05 24.0 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KII89281.1 - 0.00018 21.2 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 KII89281.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII89281.1 - 0.017 15.5 0.3 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain COMM_domain PF07258.14 KII89281.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 COMM domain DUF948 PF06103.11 KII89282.1 - 0.035 14.4 0.7 0.035 14.4 0.7 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 KII89282.1 - 0.065 13.9 15.8 0.92 10.2 2.9 3.6 2 1 1 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 KII89282.1 - 0.097 12.6 3.0 0.29 11.0 0.1 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Terminase_6 PF03237.15 KII89282.1 - 0.12 12.0 0.3 0.21 11.2 0.2 1.4 1 1 0 1 1 1 0 Terminase-like family Snapin_Pallidin PF14712.6 KII89282.1 - 0.24 11.8 11.4 0.48 10.9 0.0 4.1 2 1 2 4 4 4 0 Snapin/Pallidin NYD-SP28_assoc PF14775.6 KII89282.1 - 0.99 9.6 8.0 0.46 10.6 1.5 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF5082 PF16888.5 KII89282.1 - 2 8.7 13.4 8.4 6.7 3.8 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KII89282.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KII89282.1 - 3.3 7.0 16.4 0.092 12.1 1.5 2.4 1 1 0 2 2 2 0 FAM76 protein TSC22 PF01166.18 KII89282.1 - 3.8 7.9 11.5 4.5 7.7 0.3 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family Rootletin PF15035.6 KII89282.1 - 4.2 7.3 27.7 1.6 8.7 9.9 3.1 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.15 KII89282.1 - 5.3 7.4 31.3 7.9 6.9 8.0 2.2 1 1 1 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KII89282.1 - 6.4 6.8 31.7 9.7 6.2 15.2 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KII89282.1 - 9.3 6.5 18.3 0.42 10.8 3.0 3.9 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 Rad1 PF02144.16 KII89284.1 - 6.1e-67 225.6 0.0 9.8e-40 136.3 0.0 2.0 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Biotin_lipoyl PF00364.22 KII89285.1 - 8.9e-20 70.3 1.1 1.7e-19 69.4 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KII89285.1 - 1.8e-07 31.4 1.4 5.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 e3 binding domain QRPTase_N PF02749.16 KII89285.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Sterol-sensing PF12349.8 KII89286.1 - 6e-34 117.1 11.1 6e-34 117.1 11.1 2.3 1 1 1 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KII89286.1 - 4.5e-12 44.9 7.8 6.4e-12 44.4 7.8 1.1 1 0 0 1 1 1 1 Patched family Cwf_Cwc_15 PF04889.12 KII89288.1 - 0.00099 18.9 16.3 0.0023 17.7 13.8 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein MPS-4 PF17523.2 KII89288.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Nop14 PF04147.12 KII89288.1 - 0.99 7.5 13.4 1.4 7.0 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 KII89288.1 - 1.2 8.5 8.7 2.3 7.6 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 KII89288.1 - 4.2 6.0 5.9 6.9 5.3 5.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 KII89288.1 - 9.8 5.7 19.6 0.54 9.8 14.0 1.7 2 0 0 2 2 2 0 PPP4R2 4PPT_N PF17837.1 KII89289.1 - 0.04 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF1405 PF07187.11 KII89291.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) PI-PLC-X PF00388.19 KII89292.1 - 6.7e-05 22.5 0.0 0.00014 21.5 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain adh_short PF00106.25 KII89293.1 - 2.9e-30 105.2 0.1 2.6e-25 89.0 0.1 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII89293.1 - 9.6e-17 61.3 0.1 1.6e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89293.1 - 7.2e-07 29.3 0.1 1.1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII89293.1 - 0.00018 21.1 0.1 0.00026 20.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII89293.1 - 0.0014 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KII89293.1 - 0.0037 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KII89293.1 - 0.19 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 KII89295.1 - 6.1e-64 216.1 1.4 1e-63 215.3 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KII89295.1 - 1.7e-33 115.2 0.2 3.4e-33 114.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KII89295.1 - 5.2e-22 78.2 3.7 1.6e-18 67.0 0.3 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII89295.1 - 1.5e-14 54.0 0.5 2.7e-14 53.1 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII89295.1 - 8.3e-07 28.0 2.4 0.0044 15.8 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KII89295.1 - 4.5e-06 26.3 0.0 7.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KII89295.1 - 1e-05 24.9 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KII89295.1 - 0.00081 19.6 0.7 0.00081 19.6 0.7 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII89295.1 - 0.0023 17.1 4.5 0.017 14.2 2.3 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KII89295.1 - 0.0042 16.2 1.2 0.036 13.1 0.8 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KII89295.1 - 0.005 16.2 1.4 0.91 8.8 0.3 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KII89295.1 - 0.075 12.9 2.4 0.39 10.6 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 KII89295.1 - 0.088 12.1 0.7 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KII89295.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.8 4 0 0 4 4 3 0 FAD-NAD(P)-binding DAO PF01266.24 KII89295.1 - 0.77 9.3 5.6 4 6.9 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KII89295.1 - 1 8.5 3.4 0.47 9.7 0.2 2.0 3 0 0 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 KII89295.1 - 2.1 7.5 7.3 35 3.5 0.1 3.6 3 1 1 4 4 4 0 FAD binding domain PDE8 PF08629.10 KII89296.1 - 0.011 15.7 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase MIF PF01187.18 KII89297.1 - 4.3e-19 68.9 0.0 5e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.18 KII89298.1 - 3.5e-18 66.0 0.0 3.9e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Rpp20 PF12328.8 KII89299.1 - 8.4e-07 29.0 0.0 1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P eRF1_2 PF03464.15 KII89300.1 - 2e-45 154.4 0.0 3.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KII89300.1 - 8.2e-39 132.6 0.5 1.7e-38 131.6 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KII89300.1 - 2e-19 69.9 0.0 3.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KII89300.1 - 1.4e-09 38.3 0.1 2.2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KII89300.1 - 3.2e-08 33.9 0.0 6.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Pro-kuma_activ PF09286.11 KII89301.1 - 3e-36 124.8 0.1 5e-36 124.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII89301.1 - 0.00037 19.9 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Amidohydro_3 PF07969.11 KII89304.1 - 1.1e-13 51.5 0.1 3.3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KII89304.1 - 4.8e-10 39.3 0.1 2.1e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 KII89304.1 - 1.3e-09 37.7 0.2 0.00097 19.0 0.0 4.2 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Potex_coat PF06184.11 KII89305.1 - 0.058 13.0 0.2 0.13 11.9 0.2 1.6 1 1 0 1 1 1 0 Potexvirus coat protein RRM_1 PF00076.22 KII89306.1 - 1.2e-33 114.8 0.0 3.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII89306.1 - 0.023 14.8 0.0 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 KII89306.1 - 0.12 12.1 0.2 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Ras PF00071.22 KII89308.1 - 5.6e-54 182.1 0.0 6.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89308.1 - 4e-19 69.0 0.0 5.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII89308.1 - 4.1e-07 29.6 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII89308.1 - 0.027 14.0 0.1 0.18 11.3 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 KII89308.1 - 0.052 13.8 0.0 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial WD40 PF00400.32 KII89309.1 - 2.6e-06 28.1 2.5 0.0012 19.6 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89309.1 - 3e-06 27.4 0.3 0.013 15.8 0.0 3.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain M_domain PF12938.7 KII89309.1 - 0.0018 18.2 1.8 0.0018 18.2 1.8 2.5 3 0 0 3 3 3 1 M domain of GW182 DUF1077 PF06417.12 KII89311.1 - 5.9e-45 152.1 0.1 7.6e-45 151.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Senescence PF06911.12 KII89312.1 - 1.7e-45 155.6 0.3 2.5e-45 155.0 0.3 1.3 1 0 0 1 1 1 1 Senescence-associated protein Phosducin PF02114.16 KII89313.1 - 3.2e-08 32.8 0.0 6.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Phosducin Ribonuclease_3 PF00636.26 KII89314.1 - 9.4e-41 138.7 0.0 1.8e-19 70.3 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KII89314.1 - 1.8e-24 86.3 0.0 8.1e-15 55.1 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 KII89314.1 - 9.6e-16 57.7 0.1 2.7e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KII89314.1 - 1.4e-13 51.2 0.0 2.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 KII89314.1 - 5.7e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ResIII PF04851.15 KII89314.1 - 0.029 14.4 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KII89314.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase dsrm PF00035.26 KII89314.1 - 0.15 12.8 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif TetR_C_28 PF17937.1 KII89314.1 - 0.3 11.5 6.4 2.3 8.7 0.8 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CMD PF02627.20 KII89315.1 - 0.05 13.7 0.6 0.17 12.0 0.4 2.1 2 1 0 2 2 2 0 Carboxymuconolactone decarboxylase family TrbE PF11100.8 KII89316.1 - 0.027 14.7 0.4 0.092 13.0 0.4 1.9 1 0 0 1 1 1 0 Conjugal transfer protein TrbE DUF3318 PF11780.8 KII89316.1 - 0.039 13.9 0.4 0.07 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Ras PF00071.22 KII89317.1 - 1.5e-61 206.7 0.2 1.8e-61 206.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89317.1 - 1e-34 119.3 0.1 1.5e-34 118.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII89317.1 - 9e-12 44.8 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII89317.1 - 4.4e-07 30.0 0.1 6.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII89317.1 - 0.00018 21.4 0.1 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KII89317.1 - 0.00044 19.8 0.2 0.0015 18.1 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KII89317.1 - 0.0034 17.7 0.0 0.038 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KII89317.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KII89317.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KII89317.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KII89317.1 - 0.024 15.0 0.1 0.034 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KII89317.1 - 0.03 13.8 0.1 0.093 12.3 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 KII89317.1 - 0.034 14.6 0.1 0.056 14.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KII89317.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII89317.1 - 0.043 13.3 0.1 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 KII89317.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 KII89317.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain YvfG PF09628.10 KII89317.1 - 0.15 12.4 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.14 KII89317.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KII89317.1 - 0.16 11.7 0.6 0.29 10.9 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Oxidored_FMN PF00724.20 KII89318.1 - 9.2e-72 242.2 0.0 1.2e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF442 PF04273.13 KII89318.1 - 0.14 12.2 0.2 0.4 10.8 0.2 1.9 2 0 0 2 2 2 0 Putative phosphatase (DUF442) ABC_tran PF00005.27 KII89319.1 - 1.6e-42 145.3 0.1 2.8e-20 73.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KII89319.1 - 1.6e-19 70.9 1.4 1.3e-07 31.7 0.5 4.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII89319.1 - 3.3e-13 49.6 0.7 0.0012 18.3 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KII89319.1 - 1.2e-07 31.3 0.2 0.018 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KII89319.1 - 5.3e-06 27.0 0.1 0.013 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII89319.1 - 6.5e-06 26.5 0.0 0.15 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KII89319.1 - 7.7e-06 26.2 0.0 0.0034 17.5 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KII89319.1 - 1.5e-05 25.0 0.2 0.059 13.3 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase HEAT_2 PF13646.6 KII89319.1 - 2.8e-05 24.4 12.2 0.036 14.4 0.2 3.8 2 1 1 3 3 3 2 HEAT repeats Chromo PF00385.24 KII89319.1 - 3e-05 23.8 0.1 7.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KII89319.1 - 3.6e-05 23.8 0.4 0.25 11.4 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KII89319.1 - 3.8e-05 24.1 1.6 0.036 14.5 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 KII89319.1 - 5.7e-05 23.5 0.0 0.25 11.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_15 PF13175.6 KII89319.1 - 0.00013 21.8 1.0 0.32 10.6 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 KII89319.1 - 0.00014 21.8 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KII89319.1 - 0.00023 21.8 12.0 0.0067 17.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KII89319.1 - 0.00028 21.1 0.0 0.59 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KII89319.1 - 0.00036 21.0 0.0 2.6 8.5 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KII89319.1 - 0.00055 19.0 0.3 0.29 10.1 0.1 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KII89319.1 - 0.00074 19.5 0.4 5.6 6.8 0.0 3.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KII89319.1 - 0.00076 19.7 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 KII89319.1 - 0.0018 18.4 6.9 0.56 10.6 0.0 5.7 6 0 0 6 6 5 1 HEAT repeat 4HB PF17947.1 KII89319.1 - 0.002 18.1 0.0 0.0083 16.2 0.0 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_30 PF13604.6 KII89319.1 - 0.0037 17.0 0.2 4.9 6.8 0.2 2.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KII89319.1 - 0.0038 16.7 0.4 3.1 7.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KII89319.1 - 0.008 15.4 0.1 2.6 7.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KII89319.1 - 0.0089 15.8 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KII89319.1 - 0.016 13.9 0.0 2.2 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KII89319.1 - 0.019 15.2 1.1 1.6 9.1 0.0 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KII89319.1 - 0.02 15.1 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KII89319.1 - 0.023 13.9 0.0 4.9 6.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 KII89319.1 - 0.026 14.6 0.1 0.42 10.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 KII89319.1 - 0.033 14.2 0.4 12 5.9 0.1 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HEAT_EZ PF13513.6 KII89319.1 - 0.048 14.2 10.7 0.19 12.3 1.0 5.1 4 1 2 6 6 6 0 HEAT-like repeat NTPase_1 PF03266.15 KII89319.1 - 0.056 13.4 0.1 7 6.5 0.0 2.8 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KII89319.1 - 0.065 13.0 2.4 12 5.6 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_27 PF13514.6 KII89319.1 - 0.073 12.6 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KII89319.1 - 0.078 12.6 1.6 6.3 6.4 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF3437 PF11919.8 KII89319.1 - 0.11 12.5 1.0 0.72 9.8 0.1 3.0 4 0 0 4 4 1 0 Domain of unknown function (DUF3437) ATP-synt_ab PF00006.25 KII89319.1 - 0.15 11.7 0.0 4.7 6.8 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 KII89319.1 - 0.16 11.2 1.0 0.54 9.4 0.0 2.3 3 0 0 3 3 3 0 KAP family P-loop domain AAA_14 PF13173.6 KII89319.1 - 0.16 12.0 0.1 12 6.0 0.1 3.2 3 1 0 3 3 2 0 AAA domain U3snoRNP10 PF12397.8 KII89319.1 - 0.19 12.1 1.0 0.6 10.5 0.8 2.0 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 ATP_bind_1 PF03029.17 KII89319.1 - 0.21 11.3 0.5 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KII89319.1 - 0.52 10.3 4.4 14 5.6 0.1 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) V_ATPase_I PF01496.19 KII89320.1 - 0 1067.8 0.0 0 1067.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 KII89320.1 - 4.3 8.0 5.1 1.9 9.2 1.6 2.3 3 0 0 3 3 3 0 SlyX Lactamase_B PF00753.27 KII89321.1 - 1.9e-18 67.2 4.3 5e-18 65.8 4.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 KII89321.1 - 7.5e-16 57.8 0.1 6.3e-15 54.9 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 KII89321.1 - 0.00015 21.4 0.2 0.00034 20.2 0.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain VCBS PF13517.6 KII89322.1 - 8.6e-25 87.1 15.4 8.5e-10 39.1 0.2 5.9 4 2 2 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KII89322.1 - 1.8e-06 28.0 18.3 0.4 10.8 0.4 6.3 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 KII89322.1 - 0.38 10.1 6.3 13 5.1 0.1 4.8 4 2 2 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region Peptidase_M50B PF13398.6 KII89323.1 - 2.6e-57 193.7 21.2 3.4e-57 193.3 21.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like FAD_binding_3 PF01494.19 KII89324.1 - 5.5e-22 78.5 0.2 1.5e-21 77.0 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KII89324.1 - 1.2e-06 28.6 0.5 3.1e-06 27.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII89324.1 - 8.3e-06 25.6 0.9 1.5e-05 24.8 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII89324.1 - 6.7e-05 22.1 0.7 9.4e-05 21.6 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII89324.1 - 0.00014 21.2 2.2 0.00054 19.3 2.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII89324.1 - 0.00029 20.1 1.6 0.00053 19.2 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KII89324.1 - 0.00065 20.2 0.2 0.0014 19.1 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII89324.1 - 0.0013 18.1 1.4 0.0022 17.4 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KII89324.1 - 0.003 16.7 1.2 0.0048 16.0 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KII89324.1 - 0.0071 15.7 0.3 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KII89324.1 - 0.029 13.7 1.0 0.031 13.6 0.2 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KII89324.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII89324.1 - 0.12 11.1 1.3 0.18 10.5 1.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 KII89324.1 - 0.18 10.6 2.9 4 6.2 0.9 2.9 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.18 KII89324.1 - 0.2 11.5 0.8 0.52 10.2 0.8 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_2 PF12680.7 KII89325.1 - 2.9e-06 27.8 0.1 5.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KII89325.1 - 3.6e-05 23.6 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase MA3 PF02847.17 KII89326.1 - 5e-25 87.7 0.0 1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KII89326.1 - 3.8e-10 39.8 0.1 1.9e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain VGPC1_C PF16799.5 KII89326.1 - 0.058 13.4 0.1 0.25 11.3 0.4 2.0 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DNA_pol_phi PF04931.13 KII89326.1 - 2 6.4 11.1 3.3 5.7 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cerato-platanin PF07249.12 KII89328.1 - 5.9e-33 113.5 1.2 7e-33 113.3 1.2 1.1 1 0 0 1 1 1 1 Cerato-platanin DDE_3 PF13358.6 KII89329.1 - 6e-09 35.8 0.7 0.0084 15.9 0.0 3.4 3 0 0 3 3 3 3 DDE superfamily endonuclease Exonuc_V_gamma PF04257.14 KII89329.1 - 0.032 12.5 0.0 0.046 11.9 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit HTH_33 PF13592.6 KII89329.1 - 0.036 13.7 0.1 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix JLPA PF16668.5 KII89329.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Adhesin from Campylobacter Isochorismatase PF00857.20 KII89337.1 - 2.2e-30 106.1 0.0 2.6e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family GAS PF13851.6 KII89339.1 - 0.00058 19.3 4.9 0.00093 18.6 4.9 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CLZ PF16526.5 KII89339.1 - 0.73 10.2 6.9 1.1 9.7 3.2 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4472 PF14739.6 KII89339.1 - 1.8 9.3 7.1 3.2 8.5 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) F-box-like PF12937.7 KII89340.1 - 2.9e-12 46.3 1.1 6.8e-12 45.1 0.4 2.0 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.28 KII89340.1 - 1.8e-08 33.9 0.1 0.00061 19.5 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII89340.1 - 8.9e-07 28.6 1.4 0.0017 18.3 0.3 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 KII89340.1 - 5.9e-05 22.8 0.1 0.00085 19.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain TPR_9 PF13371.6 KII89340.1 - 0.0002 21.4 3.4 0.24 11.6 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII89340.1 - 0.00041 20.3 2.3 0.14 12.4 0.2 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII89340.1 - 0.0043 17.3 1.9 0.01 16.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII89340.1 - 0.062 13.8 4.7 0.25 11.9 0.4 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KII89340.1 - 0.065 13.6 1.4 0.37 11.3 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 KII89340.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 KII89340.1 - 0.19 11.4 0.7 0.47 10.2 0.7 1.7 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 KII89340.1 - 0.22 12.2 0.1 0.22 12.2 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII89340.1 - 4.8 8.3 9.6 7 7.8 0.5 3.9 2 1 2 4 4 3 0 Tetratricopeptide repeat Glyoxalase_3 PF13468.6 KII89341.1 - 1.1e-31 110.3 0.0 2.2e-31 109.3 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KII89341.1 - 0.0098 16.2 0.0 2.3 8.5 0.0 2.8 2 1 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Asp PF00026.23 KII89342.1 - 2.5e-82 276.8 10.5 3.1e-82 276.5 10.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII89342.1 - 2.8e-07 31.0 8.8 5.4e-05 23.5 6.3 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII89342.1 - 0.00035 20.4 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal WD40 PF00400.32 KII89343.1 - 3.3e-43 144.8 18.4 4e-07 30.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89343.1 - 1.3e-20 73.4 0.0 9.7e-06 25.8 0.1 6.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII89343.1 - 1.3e-09 38.2 0.4 2e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KII89343.1 - 4e-08 32.6 0.3 0.081 11.9 0.1 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KII89343.1 - 7.4e-05 21.7 0.1 1.3 7.6 0.0 3.9 1 1 2 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.14 KII89343.1 - 0.00041 19.5 0.0 0.00068 18.8 0.0 1.3 1 1 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.12 KII89343.1 - 0.068 11.1 0.0 0.11 10.5 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Frtz PF11768.8 KII89343.1 - 0.12 10.7 0.0 0.25 9.6 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Det1 PF09737.9 KII89343.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 CBM_21 PF03370.13 KII89344.1 - 1.5e-26 92.7 0.0 2.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KII89344.1 - 1.1e-08 35.6 0.1 2.3e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-MYND PF01753.18 KII89345.1 - 2e-09 37.4 12.1 3e-09 36.8 12.1 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KII89345.1 - 0.058 13.5 7.2 0.23 11.6 7.2 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KII89345.1 - 0.44 10.5 6.5 0.86 9.5 6.5 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 KII89347.1 - 1.5e-07 31.3 9.3 2.5e-07 30.7 9.3 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KII89347.1 - 0.032 14.1 5.8 0.055 13.4 5.8 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.6 KII89347.1 - 4.8 7.4 9.7 32 4.7 9.7 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 KAP PF05804.12 KII89348.1 - 0.14 10.3 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Zn_clus PF00172.18 KII89349.1 - 5.6e-07 29.6 15.4 1.4e-06 28.3 15.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII89349.1 - 0.00028 20.0 0.1 0.0005 19.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FlxA PF14282.6 KII89349.1 - 0.034 14.1 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein GreA_GreB_N PF03449.15 KII89349.1 - 0.21 11.7 0.5 0.51 10.5 0.5 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Copper-fist PF00649.18 KII89349.1 - 5.9 6.5 13.1 0.041 13.4 2.8 2.6 3 0 0 3 3 3 0 Copper fist DNA binding domain ADK PF00406.22 KII89350.1 - 5e-58 195.5 0.0 6.2e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KII89350.1 - 3.1e-20 73.0 0.3 6.5e-20 72.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KII89350.1 - 1.7e-16 59.9 0.0 3.4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KII89350.1 - 0.00041 20.9 0.0 0.00079 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DDOST_48kD PF03345.14 KII89351.1 - 7.2e-132 440.1 0.0 8.4e-132 439.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BCSC_C PF05420.11 KII89351.1 - 0.045 12.9 0.1 0.069 12.3 0.1 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Plavaka PF18759.1 KII89352.1 - 4.3e-129 430.4 0.0 5.8e-129 430.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase SnoaL_2 PF12680.7 KII89352.1 - 0.13 13.0 0.5 0.78 10.4 0.5 2.4 1 0 0 1 1 1 0 SnoaL-like domain P66_CC PF16563.5 KII89353.1 - 0.12 11.9 1.0 0.35 10.5 1.0 1.7 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Plavaka PF18759.1 KII89354.1 - 1.5e-10 40.8 0.0 1.7e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase DEPP PF15343.6 KII89356.1 - 2.6 8.1 12.0 1.5 8.9 0.7 3.2 1 1 2 3 3 3 0 Decidual protein induced by progesterone family DUF446 PF04287.12 KII89357.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Pkinase PF00069.25 KII89359.1 - 3.4e-49 167.6 0.0 1.3e-48 165.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89359.1 - 1.1e-26 93.7 0.0 3.4e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KII89359.1 - 6.5e-05 22.4 0.1 0.0001 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII89359.1 - 0.00031 20.1 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Herpes_LMP1 PF05297.11 KII89360.1 - 0.13 11.4 6.6 0.19 10.9 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ORMDL PF04061.14 KII89360.1 - 1.1 9.0 7.3 0.38 10.6 2.9 2.4 2 1 1 3 3 3 0 ORMDL family HemY_N PF07219.13 KII89360.1 - 4 7.7 10.2 0.64 10.2 5.7 2.0 1 1 1 2 2 2 0 HemY protein N-terminus Cerato-platanin PF07249.12 KII89363.1 - 1.1e-21 77.1 3.0 4.5e-21 75.2 3.0 1.8 1 1 0 1 1 1 1 Cerato-platanin CEBP_ZZ PF16366.5 KII89363.1 - 0.15 12.3 1.3 0.29 11.4 1.3 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pkinase PF00069.25 KII89365.1 - 4.4e-34 118.0 0.0 5.1e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89365.1 - 2e-12 46.9 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII89365.1 - 1.3e-05 24.6 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII89365.1 - 7.6e-05 22.2 0.0 0.00042 19.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII89365.1 - 0.086 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Rhodanese_C PF12368.8 KII89370.1 - 0.058 13.8 0.8 0.12 12.8 0.8 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Cerato-platanin PF07249.12 KII89371.1 - 4e-40 136.6 2.0 4.7e-40 136.4 2.0 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KII89371.1 - 0.001 18.9 0.3 0.0016 18.3 0.3 1.4 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 KII89372.1 - 1.5e-33 115.4 1.3 1.8e-33 115.2 1.3 1.1 1 0 0 1 1 1 1 Cerato-platanin COX17 PF05051.13 KII89375.1 - 5.5e-21 74.7 4.5 6.3e-21 74.5 4.5 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L32p PF01783.23 KII89375.1 - 0.087 13.1 0.4 0.087 13.1 0.4 1.7 1 1 1 2 2 2 0 Ribosomal L32p protein family E1-E2_ATPase PF00122.20 KII89378.1 - 1.3e-46 158.4 3.9 2.9e-46 157.2 1.8 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KII89378.1 - 3.7e-20 73.1 0.0 1.9e-18 67.5 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KII89378.1 - 5.1e-20 71.9 19.5 1e-15 57.9 1.8 3.9 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KII89378.1 - 3.4e-19 68.7 0.0 7.5e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KII89378.1 - 6.4e-14 51.4 0.0 1.3e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII89378.1 - 0.00031 20.6 0.5 0.038 13.7 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1691 PF07950.11 KII89379.1 - 3.5e-05 24.5 0.9 0.00038 21.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) VirC2 PF07181.11 KII89382.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 VirC2 protein Peptidase_S10 PF00450.22 KII89383.1 - 2.2e-104 350.2 0.0 2.7e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Shisa PF13908.6 KII89384.1 - 0.033 14.4 0.4 0.033 14.4 0.4 2.6 2 2 1 3 3 3 0 Wnt and FGF inhibitory regulator MIT PF04212.18 KII89384.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain BASP1 PF05466.12 KII89384.1 - 4.1 7.4 9.9 5.1 7.0 2.0 2.2 2 0 0 2 2 2 0 Brain acid soluble protein 1 (BASP1 protein) HMG_box PF00505.19 KII89386.1 - 3.1e-10 40.3 5.8 1e-09 38.7 5.8 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII89386.1 - 4.4e-06 27.2 0.5 1e-05 26.0 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain Polysacc_lyase PF14099.6 KII89387.1 - 0.00055 19.9 0.1 0.0023 17.8 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide lyase OPT PF03169.15 KII89388.1 - 1.1e-194 648.6 63.5 1.3e-194 648.4 63.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4229 PF14012.6 KII89388.1 - 5.3 7.2 11.4 26 5.0 5.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Methyltransf_31 PF13847.6 KII89389.1 - 5.2e-17 62.1 0.1 8.5e-17 61.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII89389.1 - 5.4e-17 62.1 0.0 7.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII89389.1 - 1.3e-16 61.0 0.2 3.6e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII89389.1 - 1.1e-14 54.9 0.1 2.4e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII89389.1 - 4.1e-12 46.7 0.1 1.2e-11 45.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII89389.1 - 1.4e-07 31.1 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KII89389.1 - 7.9e-06 25.5 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KII89389.1 - 5.6e-05 22.7 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KII89389.1 - 0.00016 20.7 0.0 0.00021 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KII89389.1 - 0.0003 20.8 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KII89389.1 - 0.00061 19.2 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 KII89389.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 KII89389.1 - 0.015 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme TPMT PF05724.11 KII89389.1 - 0.072 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CmcI PF04989.12 KII89389.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase IMS PF00817.20 KII89390.1 - 2.2e-41 141.3 0.0 4.1e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KII89390.1 - 1.4e-25 89.5 4.2 2.7e-25 88.6 4.2 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KII89390.1 - 3.5e-15 56.7 0.0 9.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KII89390.1 - 1.6e-09 38.1 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain UBM PF14377.6 KII89390.1 - 5e-07 28.9 8.0 0.00086 18.7 1.3 3.2 3 0 0 3 3 3 2 Ubiquitin binding region IMS_HHH PF11798.8 KII89390.1 - 5e-06 26.5 0.0 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KII89390.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KII89390.1 - 0.0013 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.11 KII89390.1 - 0.0047 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1805) Furin-like_2 PF15913.5 KII89391.1 - 2.7e-06 27.5 27.5 9.9e-06 25.7 15.4 6.9 1 1 6 7 7 7 4 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 KII89391.1 - 0.0032 17.8 13.0 0.0032 17.8 13.0 12.9 11 3 0 11 11 11 2 EGF-like domain GF_recep_IV PF14843.6 KII89391.1 - 0.0064 16.3 21.7 0.0064 16.3 21.7 6.1 1 1 4 6 6 6 4 Growth factor receptor domain IV VSP PF03302.13 KII89391.1 - 0.0099 14.8 159.2 0.017 14.0 23.1 6.9 1 1 4 5 5 5 3 Giardia variant-specific surface protein DUF4381 PF14316.6 KII89391.1 - 0.12 12.6 4.5 0.24 11.7 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 KII89391.1 - 0.19 11.5 0.9 0.44 10.4 0.9 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PP2C PF00481.21 KII89392.1 - 8.3e-21 74.8 0.0 2.3e-18 66.8 0.0 2.8 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KII89392.1 - 0.0016 18.4 0.0 0.058 13.3 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cyt_c_ox_IV PF12270.8 KII89393.1 - 0.099 12.8 8.3 0.2 11.8 3.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Glycos_transf_1 PF00534.20 KII89397.1 - 3.3e-24 85.3 0.0 9.7e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KII89397.1 - 2.4e-15 57.0 0.5 4e-15 56.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KII89397.1 - 6.4e-12 46.1 0.0 1.6e-10 41.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KII89397.1 - 3.6e-09 37.2 0.6 2.3e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KII89397.1 - 0.0022 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ccdc124 PF06244.12 KII89402.1 - 2.8e-28 99.1 19.9 2.8e-28 99.1 19.9 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Calcipressin PF04847.12 KII89403.1 - 7e-33 113.9 0.0 7.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Calcipressin F-box-like PF12937.7 KII89404.1 - 2.1e-06 27.5 0.6 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 KII89404.1 - 0.12 13.1 0.2 0.68 10.7 0.2 2.4 1 0 0 1 1 1 0 Leucine Rich Repeat F-box PF00646.33 KII89404.1 - 0.13 12.1 7.0 0.57 10.1 3.6 3.3 2 1 0 2 2 2 0 F-box domain BTB PF00651.31 KII89405.1 - 1.9e-07 31.3 0.0 5e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Laminin_G_3 PF13385.6 KII89406.1 - 0.051 13.7 1.3 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily FA_desaturase PF00487.24 KII89407.1 - 2e-21 77.0 23.1 2e-21 77.0 23.1 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KII89407.1 - 0.006 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) AA_kinase PF00696.28 KII89408.1 - 2.8e-39 135.2 2.7 3.7e-39 134.8 2.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KII89408.1 - 4.1e-10 39.5 3.9 1.2e-05 25.1 0.2 2.8 3 0 0 3 3 3 2 PUA domain DOPA_dioxygen PF08883.11 KII89409.1 - 2e-28 98.7 0.2 2.5e-28 98.4 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Pribosyltran_N PF13793.6 KII89410.1 - 2e-50 169.6 0.1 1.6e-49 166.7 0.1 2.3 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KII89410.1 - 2.1e-40 138.7 0.3 2.8e-36 125.3 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KII89410.1 - 7.9e-17 61.2 0.2 4.5e-15 55.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KII89410.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KII89410.1 - 0.07 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Per1 PF04080.13 KII89413.1 - 7.3e-99 330.7 10.2 8.6e-99 330.4 10.2 1.0 1 0 0 1 1 1 1 Per1-like family Ceramidase PF05875.12 KII89413.1 - 0.064 12.7 6.4 3 7.2 6.4 2.2 1 1 0 1 1 1 0 Ceramidase Hist_deacetyl PF00850.19 KII89414.1 - 3.1e-82 276.5 0.1 3.9e-82 276.2 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_transf_28 PF03033.20 KII89415.1 - 9.2e-23 80.8 0.0 2.5e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KII89415.1 - 3.2e-06 27.4 0.1 1.4e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KII89415.1 - 0.00082 18.3 0.5 0.0016 17.3 0.5 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 KII89415.1 - 0.024 14.4 0.3 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Vacuolar-sorting-associated 13 protein C-terminal Glyco_tran_28_C PF04101.16 KII89415.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PAP1 PF08601.10 KII89415.1 - 0.43 10.3 9.0 0.49 10.1 8.0 1.5 2 0 0 2 2 2 0 Transcription factor PAP1 RNA_pol PF00940.19 KII89416.1 - 1.5e-06 27.3 0.0 1.6e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RNA_polI_A34 PF08208.11 KII89417.1 - 1.3e-27 97.2 3.2 1.3e-27 97.2 3.2 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Ada3 PF10198.9 KII89418.1 - 2.5e-26 92.4 0.0 2.5e-26 92.4 0.0 2.5 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.16 KII89418.1 - 0.002 16.7 0.6 0.002 16.7 0.6 2.2 2 0 0 2 2 2 1 Herpesvirus UL25 family MgtE PF01769.16 KII89419.1 - 2e-44 150.9 18.3 4.1e-24 85.3 7.7 3.2 2 1 1 3 3 3 2 Divalent cation transporter ADH_zinc_N PF00107.26 KII89420.1 - 8.8e-13 48.4 0.1 1.7e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89420.1 - 1.5e-09 37.7 0.0 3.5e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89420.1 - 3.5e-05 24.9 0.0 5.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phos_pyr_kin PF08543.12 KII89421.1 - 3.9e-82 275.3 0.0 3e-81 272.4 0.0 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KII89421.1 - 5.7e-39 134.1 0.0 8.6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KII89421.1 - 3.4e-05 23.3 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ADH_zinc_N PF00107.26 KII89422.1 - 1.5e-14 54.1 0.1 2.3e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89422.1 - 1.3e-10 41.1 0.0 3e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89422.1 - 0.001 20.1 0.0 0.0016 19.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII89422.1 - 0.05 13.5 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase HhH-GPD PF00730.25 KII89423.1 - 1.9e-17 63.6 0.0 3.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 KII89423.1 - 0.11 13.1 0.0 5 7.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Mak10 PF04112.13 KII89424.1 - 4.6e-53 179.2 0.0 7.8e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.25 KII89425.1 - 4.2e-73 246.2 0.0 5e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 KII89425.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) GMC_oxred_N PF00732.19 KII89426.1 - 3.2e-59 200.7 0.0 3.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII89426.1 - 7.1e-33 114.1 0.1 1.2e-32 113.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KII89426.1 - 0.0012 19.1 0.2 0.0025 18.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII89426.1 - 0.004 16.3 0.1 0.094 11.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KII89426.1 - 0.0043 16.3 0.0 0.011 15.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII89426.1 - 0.0043 16.7 3.3 0.1 12.1 3.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII89426.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.26 KII89427.1 - 1.4e-12 47.8 0.1 2.5e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89427.1 - 8.5e-10 38.5 0.0 2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89427.1 - 6.2e-06 27.3 0.0 1e-05 26.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII89427.1 - 0.074 12.9 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase SUV3_C PF12513.8 KII89428.1 - 7.1e-15 54.7 0.0 1.9e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KII89428.1 - 6.4e-11 42.6 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MRP-S33 PF08293.11 KII89429.1 - 3.5e-28 97.7 1.6 4.2e-28 97.4 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Spo12 PF05032.12 KII89429.1 - 0.063 13.2 0.5 0.93 9.5 0.2 2.3 2 0 0 2 2 2 0 Spo12 family TT_ORF1 PF02956.14 KII89431.1 - 9.7 4.7 9.2 14 4.2 9.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 p450 PF00067.22 KII89432.1 - 8.8e-05 21.4 0.0 0.00026 19.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 LRR_4 PF12799.7 KII89436.1 - 0.049 14.1 3.9 23 5.6 0.2 5.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) adh_short_C2 PF13561.6 KII89437.1 - 1.4e-44 152.4 0.4 2.2e-44 151.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII89437.1 - 1.5e-43 148.5 0.5 3.9e-43 147.2 0.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII89437.1 - 1.3e-05 25.2 0.0 1.9e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII89437.1 - 4.5e-05 23.0 0.0 0.13 11.7 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KII89437.1 - 0.0052 16.1 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 KII89437.1 - 0.016 15.2 0.3 0.037 14.1 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 KII89437.1 - 0.065 13.7 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KII89437.1 - 0.076 12.9 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IPK PF03770.16 KII89438.1 - 9.5e-42 143.1 0.0 1.3e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GCIP PF13324.6 KII89438.1 - 0.18 11.4 0.9 0.3 10.7 0.9 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 KII89438.1 - 1 9.8 7.5 2 8.9 7.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RhoGEF PF00621.20 KII89440.1 - 4.9e-42 144.2 2.2 9.3e-42 143.3 2.2 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 KII89440.1 - 1.8e-21 75.7 2.7 2.1e-11 43.5 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KII89440.1 - 2.2e-19 68.8 0.6 3.4e-10 39.3 0.1 2.5 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.7 KII89440.1 - 1.4e-15 57.1 0.0 3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 KII89440.1 - 2e-15 56.9 3.0 3.5e-14 52.9 0.0 2.9 2 1 0 2 2 1 1 Pleckstrin homology domain SH3_2 PF07653.17 KII89440.1 - 9.4e-11 41.2 0.1 0.00041 20.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 KII89440.1 - 1.6e-09 37.3 0.4 3.2e-09 36.3 0.4 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 KII89440.1 - 1.4e-05 24.3 0.1 0.05 13.2 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KII89440.1 - 5.1e-05 23.6 0.1 0.00023 21.5 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain pair PH PF00169.29 KII89440.1 - 0.00017 22.1 0.0 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 KII89440.1 - 0.00058 19.6 0.3 1.1 9.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain DUF1720 PF08226.11 KII89440.1 - 0.0017 18.7 55.5 0.0017 18.7 55.5 7.1 4 2 2 6 6 2 1 Domain of unknown function (DUF1720) EF-hand_8 PF13833.6 KII89440.1 - 0.033 14.0 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair zf-MYND PF01753.18 KII89441.1 - 4.3e-11 42.7 9.7 4.3e-11 42.7 9.7 2.3 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KII89441.1 - 0.29 11.5 11.7 0.081 13.2 7.1 2.4 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 KII89441.1 - 3.2 7.7 15.7 1.3 9.0 4.5 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-C2H2_3 PF13878.6 KII89441.1 - 8.5 6.3 9.0 8.2 6.3 0.6 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO CDC73_C PF05179.14 KII89442.1 - 1.7e-54 183.8 0.1 3.1e-54 182.9 0.1 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KII89442.1 - 8.1e-08 31.9 0.0 0.004 16.5 0.0 2.4 2 1 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal MFS_1 PF07690.16 KII89443.1 - 3.7e-36 124.8 25.1 3.7e-36 124.8 25.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII89443.1 - 4.1e-17 62.2 3.7 4.1e-17 62.2 3.7 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KII89443.1 - 2.6e-05 22.9 0.3 3.9e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KII89443.1 - 0.17 10.2 0.8 0.34 9.2 0.0 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.26 KII89444.1 - 8.4e-17 61.4 0.3 1.6e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89444.1 - 2.6e-09 36.9 0.0 5.3e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89444.1 - 0.0074 17.3 0.0 0.013 16.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII89444.1 - 0.037 13.5 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RasGEF PF00617.19 KII89445.1 - 1.1e-53 182.0 0.1 2.2e-53 181.1 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII89445.1 - 4.6e-20 71.8 0.1 9.8e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif WW PF00397.26 KII89445.1 - 0.062 13.4 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 WW domain Pkinase PF00069.25 KII89447.1 - 1.9e-11 43.8 0.0 3.3e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89447.1 - 4.6e-06 26.1 0.0 8.8e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII89448.1 - 6.1e-09 35.6 0.0 2.5e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89448.1 - 0.00041 19.7 0.0 0.00096 18.5 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase ABC1 PF03109.16 KII89448.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Lipase_3 PF01764.25 KII89449.1 - 4.1e-06 26.7 0.0 9.2e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII89449.1 - 0.11 13.1 2.5 0.35 11.4 2.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 KII89449.1 - 0.16 11.9 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) F-box-like PF12937.7 KII89450.1 - 6.1e-07 29.2 0.0 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KII89450.1 - 0.013 15.5 0.1 0.051 13.6 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeat LRR_4 PF12799.7 KII89450.1 - 0.061 13.8 0.2 0.54 10.8 0.0 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII89450.1 - 0.17 11.7 0.6 0.73 9.6 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat ADH_zinc_N PF00107.26 KII89451.1 - 1.6e-13 50.8 0.9 4.9e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89451.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89451.1 - 0.0014 19.7 0.0 0.0026 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89452.1 - 5.4e-15 55.5 0.0 9.1e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89452.1 - 7.7e-08 32.2 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89452.1 - 6.7e-06 27.2 0.0 1.2e-05 26.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII89452.1 - 0.049 13.1 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus OPA3 PF07047.12 KII89453.1 - 1.7e-44 150.6 0.5 2e-44 150.4 0.0 1.3 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Dor1 PF04124.12 KII89453.1 - 0.046 12.4 0.2 0.068 11.8 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family APG17 PF04108.12 KII89453.1 - 0.053 12.6 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 IMD PF08397.11 KII89453.1 - 0.075 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Cellulase PF00150.18 KII89454.1 - 5.3e-15 55.6 1.9 3.9e-09 36.3 0.0 3.1 3 1 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KII89454.1 - 6.6e-09 36.2 0.1 2.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KII89454.1 - 0.0042 16.7 0.1 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 eIF2A PF08662.11 KII89455.1 - 1.5e-79 266.4 0.0 4.3e-78 261.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KII89455.1 - 0.0019 19.0 0.5 0.27 12.2 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KII89455.1 - 0.11 12.2 2.0 56 3.6 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature SelK_SelG PF10961.8 KII89460.1 - 0.11 13.1 3.3 0.18 12.4 3.3 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Rota_NS26 PF01525.16 KII89461.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Rotavirus NS26 DUF1143 PF06608.11 KII89462.1 - 0.075 13.1 0.6 12 6.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1143) Yip1 PF04893.17 KII89466.1 - 0.0013 18.5 2.6 0.0018 18.0 2.6 1.1 1 0 0 1 1 1 1 Yip1 domain RseC_MucC PF04246.12 KII89466.1 - 3.8 7.5 5.5 7.6 6.5 5.5 1.5 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.16 KII89467.1 - 5e-45 154.0 47.5 5.2e-44 150.6 47.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KII89467.1 - 2.7e-10 39.3 12.4 4.1e-10 38.7 12.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_Ag35 PF03286.14 KII89467.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4554 PF15091.6 KII89469.1 - 1.8 7.4 6.4 1.9 7.3 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF1179 PF06678.11 KII89471.1 - 0.44 10.6 4.2 1.3 9.1 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Shugoshin_C PF07557.11 KII89472.1 - 5.4e-12 45.3 4.7 3.7e-11 42.6 4.7 2.7 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.11 KII89472.1 - 3e-07 30.2 1.6 5.8e-07 29.3 1.6 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TYA PF01021.19 KII89472.1 - 0.0067 16.7 4.7 0.031 14.6 4.7 2.2 1 0 0 1 1 1 1 TYA transposon protein Cyclase PF04199.13 KII89473.1 - 7.5e-16 58.6 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pkinase PF00069.25 KII89474.1 - 7.1e-49 166.5 0.0 1.4e-48 165.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89474.1 - 9.7e-25 87.3 0.0 1.9e-24 86.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII89474.1 - 0.00063 18.6 0.3 0.0012 17.7 0.3 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KII89474.1 - 0.02 13.9 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KII89474.1 - 0.025 13.9 0.4 0.045 13.1 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PG_binding_3 PF09374.10 KII89476.1 - 0.11 12.8 0.3 0.15 12.4 0.3 1.2 1 0 0 1 1 1 0 Predicted Peptidoglycan domain NCBP3 PF10309.9 KII89480.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 gag-asp_proteas PF13975.6 KII89481.1 - 0.0058 17.2 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII89481.1 - 0.041 14.5 0.0 0.091 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Synthase_beta PF11421.8 KII89485.1 - 5.5 7.8 6.6 6.3 7.6 0.0 3.2 2 1 1 3 3 3 0 ATP synthase F1 beta subunit Transposase_21 PF02992.14 KII89487.1 - 6.9e-10 38.5 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KII89487.1 - 0.00051 19.6 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Cupin_8 PF13621.6 KII89489.1 - 0.0029 17.3 2.3 0.019 14.7 0.3 2.5 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 KII89489.1 - 0.025 14.1 1.8 0.26 10.7 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein F-box-like PF12937.7 KII89491.1 - 0.0045 16.8 0.0 0.016 15.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KII89499.1 - 1.4e-06 28.9 0.1 0.008 17.0 0.0 2.6 2 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89499.1 - 6.3e-06 26.4 0.0 0.11 12.9 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain UvrD_C_2 PF13538.6 KII89502.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KII89502.1 - 0.029 12.3 0.0 0.038 11.9 0.0 1.0 1 0 0 1 1 1 0 Helicase SH3_13 PF18335.1 KII89502.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Plavaka PF18759.1 KII89509.1 - 9e-112 373.5 0.0 1.3e-111 372.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_9 PF16293.5 KII89509.1 - 4.6 7.2 5.9 5.5 6.9 0.3 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) CDC45 PF02724.14 KII89511.1 - 0.094 11.0 16.7 0.13 10.5 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KII89511.1 - 2.7 6.6 4.5 3.5 6.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4604 PF15377.6 KII89511.1 - 3.3 8.1 21.7 0.37 11.2 15.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) BSMAP PF12280.8 KII89511.1 - 3.9 7.6 5.2 7.3 6.8 4.9 1.6 1 1 0 1 1 1 0 Brain specific membrane anchored protein DUF4484 PF14831.6 KII89511.1 - 5.3 7.0 9.7 11 6.0 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) BRCT_2 PF16589.5 KII89518.1 - 1.2e-06 28.8 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Toprim_2 PF13155.6 KII89519.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Toprim-like LRR_6 PF13516.6 KII89521.1 - 5.9e-06 25.9 9.7 0.83 9.9 0.0 7.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KII89521.1 - 0.0012 19.2 10.7 2.1 8.9 0.1 6.3 5 3 3 8 8 8 3 Leucine Rich repeats (2 copies) CDC27 PF09507.10 KII89521.1 - 0.0076 15.7 17.1 0.014 14.9 17.1 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 LRR_1 PF00560.33 KII89521.1 - 0.016 15.7 0.9 2.1e+02 3.1 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat TIMELESS_C PF05029.13 KII89521.1 - 0.046 12.9 17.7 0.068 12.3 17.7 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region zf-piccolo PF05715.13 KII89521.1 - 1.9 8.7 5.9 4.9 7.4 0.9 2.8 2 1 0 2 2 2 0 Piccolo Zn-finger SRP-alpha_N PF04086.13 KII89521.1 - 2.9 7.7 15.3 4.9 7.0 15.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIF_alpha PF05793.12 KII89521.1 - 3.2 6.2 21.3 4.6 5.7 21.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) XRCC4 PF06632.12 KII89521.1 - 3.9 6.2 15.1 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pox_Ag35 PF03286.14 KII89521.1 - 5.2 6.8 22.4 0.39 10.5 16.7 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein EccE PF11203.8 KII89522.1 - 0.088 13.1 1.3 11 6.4 0.6 2.9 2 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Pkinase PF00069.25 KII89525.1 - 1.4e-38 132.8 0.0 1.9e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89525.1 - 9e-17 61.2 0.0 4.4e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII89525.1 - 0.0087 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII89525.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KII89525.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cnn_1N PF07989.11 KII89526.1 - 3.6e-23 81.5 10.7 3.6e-23 81.5 10.7 12.3 5 3 6 12 12 12 3 Centrosomin N-terminal motif 1 End3 PF12761.7 KII89526.1 - 0.0029 17.8 11.1 0.0029 17.8 11.1 8.1 3 3 5 9 9 9 2 Actin cytoskeleton-regulatory complex protein END3 Mto2_bdg PF12808.7 KII89526.1 - 0.003 17.8 9.7 0.003 17.8 9.7 10.8 10 3 0 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region UPF0242 PF06785.11 KII89526.1 - 0.0047 17.0 7.0 0.0047 17.0 7.0 9.2 3 3 4 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 KII89526.1 - 0.019 15.0 1.6 0.019 15.0 1.6 11.5 6 2 4 11 11 11 0 BRE1 E3 ubiquitin ligase MFS_1 PF07690.16 KII89528.1 - 9.4e-40 136.6 32.8 9.4e-40 136.6 32.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII89528.1 - 1.3e-09 37.5 7.9 1.3e-09 37.5 7.9 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter C2 PF00168.30 KII89529.1 - 6e-15 55.4 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain DPBB_1 PF03330.18 KII89530.1 - 1.1e-06 28.9 0.0 1.5e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KII89530.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Barwin family zf-A20 PF01754.16 KII89530.1 - 2.9 7.9 5.2 2 8.4 1.7 2.1 2 0 0 2 2 2 0 A20-like zinc finger Pectinesterase PF01095.19 KII89533.1 - 2.8e-42 144.5 1.0 3.4e-42 144.2 1.0 1.1 1 0 0 1 1 1 1 Pectinesterase ADH_zinc_N PF00107.26 KII89534.1 - 6.3e-14 52.1 0.3 2.3e-13 50.2 0.1 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89534.1 - 8.5e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89534.1 - 0.00041 21.4 0.0 0.00069 20.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89535.1 - 1e-13 51.4 0.1 1.8e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89535.1 - 2.4e-08 33.8 0.0 4.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII89535.1 - 0.032 15.3 0.0 0.055 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_hydro_3_C PF01915.22 KII89537.1 - 1.8e-64 217.5 0.0 2.6e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII89537.1 - 2.4e-39 135.6 0.0 4.6e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII89537.1 - 3.9e-23 81.3 0.7 1e-22 80.0 0.7 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KII89537.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain ADH_N PF08240.12 KII89538.1 - 1.5e-28 98.9 1.1 2.7e-28 98.0 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII89538.1 - 3.3e-25 88.6 1.1 6.3e-25 87.7 0.9 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII89538.1 - 0.0064 17.5 0.1 0.012 16.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_10 PF13237.6 KII89538.1 - 0.013 15.6 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain TTC5_OB PF16669.5 KII89538.1 - 0.11 12.1 0.5 0.32 10.7 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat protein 5 OB fold domain OppC_N PF12911.7 KII89540.1 - 0.0054 16.7 0.2 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Stevor PF17410.2 KII89540.1 - 0.17 11.4 1.3 0.24 10.9 1.3 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SOG2 PF10428.9 KII89540.1 - 0.34 10.0 31.8 0.45 9.7 31.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KII89540.1 - 1.4 7.6 10.5 1.8 7.3 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PknG_rubred PF16919.5 KII89540.1 - 3.9 7.6 12.2 25 5.0 12.2 2.3 1 1 0 1 1 1 0 Protein kinase G rubredoxin domain TFIIA PF03153.13 KII89540.1 - 8.5 6.2 10.2 14 5.5 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DBR1 PF05011.13 KII89542.1 - 4.8e-43 146.9 0.0 7.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KII89542.1 - 6.3e-07 30.1 0.6 1.1e-06 29.3 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KII89542.1 - 0.0084 15.5 0.0 0.081 12.2 0.0 2.1 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily FTCD_C PF04961.12 KII89546.1 - 5.4 6.7 0.0 5.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase Cyclin PF08613.11 KII89552.1 - 1.4e-28 100.3 0.0 1.4e-28 100.3 0.0 3.1 3 1 0 3 3 3 1 Cyclin DUF4551 PF15087.6 KII89552.1 - 9.8 4.9 13.4 6.1 5.6 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Plavaka PF18759.1 KII89553.1 - 4e-126 420.6 0.0 5.6e-126 420.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DUF4451 PF14616.6 KII89556.1 - 3.8e-06 27.1 4.1 1.2 9.3 0.0 4.0 3 1 1 4 4 4 3 Domain of unknown function (DUF4451) DUF2039 PF10217.9 KII89556.1 - 0.19 12.1 6.6 1 9.8 0.9 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2039) PHD PF00628.29 KII89556.1 - 2.7 7.9 5.8 52 3.8 0.1 4.0 4 0 0 4 4 4 0 PHD-finger RCR PF12273.8 KII89560.1 - 0.00045 20.9 24.4 0.0022 18.6 24.0 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red vMSA PF00695.19 KII89560.1 - 0.034 13.2 13.1 0.047 12.8 13.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LST1 PF05083.13 KII89560.1 - 0.25 11.6 0.2 0.4 11.0 0.2 1.3 1 0 0 1 1 1 0 LST-1 protein Brix PF04427.18 KII89561.1 - 2.3e-40 138.8 0.0 2.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain SCAB-PH PF17684.1 KII89561.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein F-box-like PF12937.7 KII89563.1 - 2.6e-11 43.2 0.1 5.8e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII89563.1 - 0.081 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain HNH_2 PF13391.6 KII89564.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease CLIP1_ZNF PF16641.5 KII89564.1 - 4.5 7.3 5.7 0.37 10.7 0.4 2.1 2 0 0 2 2 2 0 CLIP1 zinc knuckle HNH_2 PF13391.6 KII89565.1 - 0.00018 21.6 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 KII89566.1 - 9.8e-40 136.6 0.0 2.2e-16 60.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KII89566.1 - 1.2e-13 50.9 0.4 0.00011 21.6 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KII89566.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Yae1_N PF09811.9 KII89567.1 - 0.011 15.4 0.2 0.55 10.0 0.2 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal HOOK PF05622.12 KII89567.1 - 0.064 11.4 3.2 0.086 11.0 3.2 1.1 1 0 0 1 1 1 0 HOOK protein Macoilin PF09726.9 KII89567.1 - 0.4 9.2 3.1 0.55 8.7 3.1 1.1 1 0 0 1 1 1 0 Macoilin family Herpes_LMP1 PF05297.11 KII89567.1 - 0.79 8.9 2.1 1.1 8.3 2.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DnaB_bind PF10410.9 KII89568.1 - 0.15 12.3 0.2 0.27 11.4 0.2 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Retrotran_gag_2 PF14223.6 KII89569.1 - 2.4e-16 59.6 0.0 3.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII89569.1 - 0.0081 16.2 4.8 0.013 15.5 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KII89569.1 - 0.29 11.0 3.9 0.49 10.3 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-RING-like PF08746.11 KII89570.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 RING-like domain Retrotrans_gag PF03732.17 KII89572.1 - 0.0058 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Erythro-docking PF09277.11 KII89572.1 - 0.13 12.2 2.0 0.29 11.0 2.0 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking Pterin_4a PF01329.19 KII89572.1 - 0.16 12.2 1.1 1.7 8.8 0.1 2.1 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase APC1_C PF18122.1 KII89575.1 - 0.07 13.1 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain HisKA_3 PF07730.13 KII89580.1 - 0.00064 20.2 5.9 0.096 13.2 0.8 3.3 3 0 0 3 3 3 2 Histidine kinase Zn_clus PF00172.18 KII89580.1 - 0.86 9.8 9.8 4.9 7.4 4.6 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain KDZ PF18758.1 KII89581.1 - 7.2e-39 133.7 0.0 1.7e-38 132.5 0.0 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII89581.1 - 1.3e-29 102.4 0.2 4e-26 91.3 0.0 3.2 3 0 0 3 3 3 2 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII89581.1 - 0.005 17.0 0.1 0.013 15.6 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases OAD_gamma PF04277.13 KII89583.1 - 1.5 9.5 2.8 1 10.0 0.5 1.8 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Tet_JBP PF12851.7 KII89585.1 - 6.7e-07 29.0 0.0 1.5e-06 27.8 0.0 1.5 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF592 PF04574.13 KII89586.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) BacteriocIIc_cy PF12173.8 KII89587.1 - 0.01 16.0 3.7 4.3 7.7 0.0 3.3 1 1 2 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like GST_C PF00043.25 KII89587.1 - 0.05 13.8 1.6 1.5 9.1 0.2 2.6 1 1 2 3 3 3 0 Glutathione S-transferase, C-terminal domain IF3_C PF00707.22 KII89592.1 - 0.098 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain DUF4287 PF14117.6 KII89593.1 - 0.12 12.5 0.4 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) BASP1 PF05466.12 KII89594.1 - 1.1 9.2 7.7 1.6 8.7 7.7 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) PRIMA1 PF16101.5 KII89595.1 - 5.1 7.1 11.2 16 5.6 11.2 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 gag-asp_proteas PF13975.6 KII89600.1 - 0.031 14.8 0.0 0.082 13.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SurA_N_3 PF13624.6 KII89600.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 SurA N-terminal domain DUF3752 PF12572.8 KII89600.1 - 0.39 11.2 0.0 0.39 11.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3752) zf-CCHC_2 PF13696.6 KII89600.1 - 0.49 10.3 3.0 1.3 8.9 3.0 1.7 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 KII89600.1 - 1.1 9.6 5.1 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 KII89600.1 - 4.7 7.5 10.7 0.1 12.7 1.8 2.8 3 0 0 3 3 3 0 Zinc knuckle CpeT PF06206.11 KII89601.1 - 0.077 13.0 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) P34-Arc PF04045.14 KII89605.1 - 1.9e-111 371.5 1.4 2.3e-111 371.3 1.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.22 KII89606.1 - 4.9e-16 58.3 0.1 9.7e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 KII89607.1 - 9e-46 156.0 0.0 1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 KII89608.1 - 3.3e-46 156.8 0.0 3.8e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89608.1 - 1.7e-16 60.5 0.0 2.4e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KII89608.1 - 4.3e-07 30.0 0.1 0.00076 19.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KII89608.1 - 2.4e-05 23.9 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_33 PF13671.6 KII89608.1 - 0.0016 18.6 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KII89608.1 - 0.0075 16.3 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kdo_hydroxy PF11004.8 KII89608.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase AAA_25 PF13481.6 KII89608.1 - 0.042 13.4 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KII89608.1 - 0.083 13.3 0.1 0.16 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain His_Phos_1 PF00300.22 KII89608.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) AAA_28 PF13521.6 KII89608.1 - 0.11 12.7 0.0 0.44 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain FtsZ_C PF12327.8 KII89608.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DEAD PF00270.29 KII89609.1 - 2.2e-53 180.6 0.0 2.8e-52 177.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII89609.1 - 2.8e-32 111.4 0.0 5.1e-31 107.3 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII89609.1 - 5.5e-08 33.0 0.0 2.2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KII89609.1 - 0.019 13.8 0.0 0.12 11.1 0.0 2.2 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ndufs5 PF10200.9 KII89609.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CoA_binding_2 PF13380.6 KII89609.1 - 0.12 12.9 0.0 0.65 10.5 0.0 2.1 1 1 1 2 2 2 0 CoA binding domain Alba PF01918.21 KII89610.1 - 1.8e-06 27.7 0.1 0.088 12.6 0.0 2.8 3 1 0 3 3 3 2 Alba FmdE PF02663.14 KII89610.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon PHD PF00628.29 KII89611.1 - 1.5e-07 31.2 11.2 2.7e-07 30.4 11.2 1.4 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 KII89611.1 - 0.036 14.5 0.0 0.036 14.5 0.0 2.6 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif ANAPC10 PF03256.16 KII89612.1 - 1.1e-46 158.8 0.0 1.3e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KII89612.1 - 0.00011 22.3 0.0 0.00035 20.7 0.0 1.7 1 1 0 2 2 2 1 F5/8 type C domain ThiF PF00899.21 KII89613.1 - 2.7e-63 213.6 0.0 4e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KII89613.1 - 7.6e-13 48.9 0.0 2.9e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KII89613.1 - 0.0054 16.8 0.1 0.018 15.1 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KII89613.1 - 0.012 15.2 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UBX PF00789.20 KII89614.1 - 4.2e-11 42.9 0.3 6.6e-11 42.3 0.3 1.3 1 0 0 1 1 1 1 UBX domain PITH PF06201.13 KII89615.1 - 2.9e-38 131.5 0.0 3.7e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Med25_VWA PF11265.8 KII89616.1 - 1.9e-05 24.6 0.0 0.00037 20.4 0.0 2.3 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A ANAPC4_WD40 PF12894.7 KII89617.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SH3_9 PF14604.6 KII89619.1 - 4.9e-14 51.9 0.1 7.6e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII89619.1 - 9.1e-12 44.4 0.0 1.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII89619.1 - 9.7e-12 44.4 0.0 1.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain YchF-GTPase_C PF06071.13 KII89623.1 - 2.1e-35 120.8 0.1 8.9e-35 118.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KII89623.1 - 2.3e-18 66.3 0.0 6.3e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII89623.1 - 8e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 KII89623.1 - 0.0037 16.8 0.1 0.029 13.9 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 F-box-like PF12937.7 KII89625.1 - 5.9e-07 29.3 0.0 2.7e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 F-box-like SH3_9 PF14604.6 KII89626.1 - 3.9e-09 36.2 0.1 6.1e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII89626.1 - 5.9e-07 29.0 0.0 8.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII89626.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain NUDIX PF00293.28 KII89627.1 - 1.5e-11 44.4 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1192 PF06698.11 KII89629.1 - 0.0042 17.1 0.5 0.012 15.6 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Neur_chan_memb PF02932.16 KII89629.1 - 2.5 8.1 4.2 1.5 8.8 1.8 1.8 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CAP_N PF01213.19 KII89629.1 - 4.5 6.7 12.6 2.1 7.7 9.5 2.1 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MARVEL PF01284.23 KII89630.1 - 1.5e-09 38.0 6.9 2.3e-09 37.4 6.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF456 PF04306.13 KII89630.1 - 0.18 12.1 9.4 0.076 13.3 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) CcmD PF04995.14 KII89630.1 - 1.4 9.1 3.6 0.72 10.0 0.8 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF4013 PF13197.6 KII89630.1 - 3.4 7.5 10.2 6.2 6.6 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Voldacs PF03517.13 KII89631.1 - 1.7e-23 83.3 0.3 2.3e-22 79.6 0.3 2.0 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling TauD PF02668.16 KII89632.1 - 6.5e-33 114.7 0.0 1.2e-32 113.8 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KII89632.1 - 2.3e-18 66.6 0.1 7.2e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) F-box-like PF12937.7 KII89634.1 - 4.4e-07 29.7 0.1 1.1e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like Glyco_hydro_79C PF16862.5 KII89635.1 - 1.4e-07 32.4 0.0 3.5e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain MFS_1 PF07690.16 KII89636.1 - 1.1e-48 166.0 37.8 3.5e-31 108.4 16.5 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Aconitase PF00330.20 KII89637.1 - 1.2e-109 367.4 0.0 1.1e-108 364.3 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KII89637.1 - 3.5e-20 72.7 0.0 6.8e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Sde2_N_Ubi PF13019.6 KII89639.1 - 8.7e-54 181.8 0.1 1.1e-53 181.5 0.1 1.1 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain IlvN PF07991.12 KII89640.1 - 5.4e-46 156.2 0.0 9e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KII89640.1 - 3e-37 128.1 0.0 4.7e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KII89640.1 - 0.14 12.8 0.4 0.38 11.4 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.7 KII89642.1 - 4.6e-07 29.6 0.3 1.2e-06 28.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII89642.1 - 0.00086 19.7 2.9 0.16 12.4 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) Apt1 PF10351.9 KII89643.1 - 0.2 10.5 7.2 0.27 10.0 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCOM2 PF15328.6 KII89643.1 - 0.3 11.4 5.3 0.44 10.9 5.3 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Glycophorin_A PF01102.18 KII89644.1 - 0.004 17.4 0.2 0.004 17.4 0.2 2.5 1 1 2 3 3 3 1 Glycophorin A FeoB_associated PF12669.7 KII89644.1 - 0.043 14.2 0.5 0.043 14.2 0.5 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Amnionless PF14828.6 KII89644.1 - 0.051 12.4 1.0 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 Amnionless Syndecan PF01034.20 KII89644.1 - 0.12 12.3 0.8 0.22 11.5 0.8 1.3 1 0 0 1 1 1 0 Syndecan domain DUF2207 PF09972.9 KII89644.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plasmodium_Vir PF05795.11 KII89644.1 - 0.24 10.8 0.7 0.34 10.3 0.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Podoplanin PF05808.11 KII89644.1 - 6.5 6.8 17.9 35 4.5 17.9 1.9 1 1 0 1 1 1 0 Podoplanin Aminotran_3 PF00202.21 KII89646.1 - 1e-42 146.3 0.0 1.6e-39 135.7 0.0 2.9 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 KII89646.1 - 1.9e-15 57.2 0.0 3.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain PI3Ka PF00613.20 KII89648.1 - 6.1e-54 182.2 0.1 9.5e-54 181.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KII89648.1 - 1.9e-47 162.2 0.0 4e-32 112.0 0.0 3.1 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KII89648.1 - 1.5e-40 138.4 0.0 2.7e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Amidohydro_1 PF01979.20 KII89649.1 - 7.2e-67 226.1 2.8 1.2e-66 225.4 2.8 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KII89649.1 - 1.8e-54 183.2 1.4 4.5e-54 181.9 1.4 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KII89649.1 - 4.5e-42 142.0 0.1 1.3e-41 140.6 0.1 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 KII89649.1 - 2.2e-41 140.2 0.1 5.7e-41 138.8 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KII89649.1 - 2.4e-05 24.0 1.5 0.00023 20.8 0.1 2.2 1 1 0 2 2 2 1 Amidohydrolase family zf-C2H2 PF00096.26 KII89651.1 - 5e-05 23.5 8.4 5.2e-05 23.5 0.2 3.2 2 1 1 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.7 KII89651.1 - 0.00016 22.0 0.0 0.31 11.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII89651.1 - 0.0021 18.7 5.5 0.0055 17.4 0.1 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII89651.1 - 0.0045 17.2 0.0 2.9 8.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KII89651.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KII89651.1 - 0.098 12.4 0.6 4.1 7.3 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KII89651.1 - 0.46 11.0 2.8 1 9.9 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain FtsJ PF01728.19 KII89652.1 - 5e-11 43.0 0.0 7.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase HgmA PF04209.13 KII89653.1 - 2.7e-174 579.9 0.1 3.1e-174 579.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transketolase_N PF00456.21 KII89654.1 - 2.1e-16 59.8 1.8 1.8e-15 56.8 1.8 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KII89654.1 - 3e-08 33.6 0.0 6.8e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KII89654.1 - 1e-05 25.3 0.3 2.7e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KII89654.1 - 0.00021 20.3 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KII89654.1 - 0.0031 17.3 0.2 0.014 15.1 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Phosphatase PF15698.5 KII89654.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatase DUF4112 PF13430.6 KII89656.1 - 8.1e-34 116.1 0.1 1.1e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbhQ PF11076.8 KII89656.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ NAM-associated PF14303.6 KII89658.1 - 0.26 12.0 0.4 0.53 11.0 0.4 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HA2 PF04408.23 KII89659.1 - 1.4e-23 83.2 0.0 1.5e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KII89659.1 - 9.3e-15 54.8 0.0 2.7e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KII89659.1 - 9.3e-14 51.7 0.0 2.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII89659.1 - 0.004 16.9 0.1 0.0082 15.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII89660.1 - 0.0017 18.6 0.1 0.0018 18.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KII89660.1 - 0.0081 15.8 0.0 0.0082 15.8 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KII89660.1 - 0.0093 15.7 0.0 0.0098 15.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KII89660.1 - 0.014 14.7 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KII89660.1 - 0.017 15.3 0.2 0.023 14.8 0.2 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KII89660.1 - 0.021 15.3 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KII89660.1 - 0.024 14.6 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KII89660.1 - 0.036 13.8 0.0 0.036 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KII89660.1 - 0.043 14.0 0.1 0.11 12.8 0.1 1.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 KII89660.1 - 0.056 12.5 0.2 0.08 12.0 0.2 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KII89660.1 - 0.067 13.6 0.0 0.067 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KII89660.1 - 0.074 12.6 0.1 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KII89660.1 - 0.077 12.3 0.5 2 7.6 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KII89660.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 KII89660.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KII89660.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KII89660.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CHORD PF04968.12 KII89662.1 - 0.12 13.1 1.1 0.12 13.1 1.1 2.6 2 1 0 2 2 2 0 CHORD CHORD PF04968.12 KII89663.1 - 0.0043 17.7 2.9 0.07 13.9 0.4 2.4 2 0 0 2 2 2 2 CHORD CD34_antigen PF06365.12 KII89665.1 - 0.012 15.3 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Methyltransf_2 PF00891.18 KII89666.1 - 1.7e-27 96.1 0.0 1.1e-21 77.1 0.0 2.2 1 1 0 2 2 2 2 O-methyltransferase domain Methyltransf_2 PF00891.18 KII89667.1 - 3.7e-23 81.9 0.0 5.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KII89667.1 - 0.00053 20.0 0.1 0.0017 18.3 0.1 2.0 1 0 0 1 1 1 1 Dimerisation domain PCMT PF01135.19 KII89667.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MarR PF01047.22 KII89667.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 MarR family MTS PF05175.14 KII89667.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ricin_B_lectin PF00652.22 KII89668.1 - 4.5e-17 62.5 0.0 1e-05 25.8 0.0 4.2 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KII89668.1 - 2.7e-10 40.8 1.9 0.067 13.9 0.0 4.7 4 1 1 5 5 5 3 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 KII89668.1 - 0.0057 16.6 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 2 FIST C domain RsgI_N PF12791.7 KII89668.1 - 0.19 11.7 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Profilin PF00235.19 KII89669.1 - 6.4e-08 32.9 0.0 1.1e-07 32.2 0.0 1.4 1 1 0 1 1 1 1 Profilin COX4 PF02936.14 KII89671.1 - 0.25 11.3 0.1 0.34 10.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Tubulin PF00091.25 KII89672.1 - 4.5e-62 209.8 0.0 6.3e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KII89672.1 - 1e-36 125.9 0.0 1.6e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KII89672.1 - 6.2e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KII89672.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Methyltransf_2 PF00891.18 KII89673.1 - 1.7e-26 92.8 0.0 1.3e-21 76.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KII89673.1 - 0.016 15.2 0.2 0.055 13.5 0.1 2.0 2 0 0 2 2 2 0 Dimerisation domain Cyanate_lyase PF02560.14 KII89675.1 - 3.1e-33 113.4 0.0 4.4e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KII89675.1 - 0.002 18.5 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 KII89675.1 - 0.0072 16.4 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.12 KII89675.1 - 0.031 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 KorB PF08535.10 KII89675.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 KorB domain HTH_19 PF12844.7 KII89675.1 - 0.093 12.8 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r1_1 PF03979.14 KII89675.1 - 0.23 11.5 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Complex1_LYR_2 PF13233.6 KII89676.1 - 1.3e-21 77.1 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KII89676.1 - 2.6e-12 46.6 0.0 4.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KII89676.1 - 0.0093 16.6 0.1 0.015 15.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF4604 PF15377.6 KII89677.1 - 5e-30 105.2 12.3 6.3e-30 104.9 12.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) QRPTase_C PF01729.19 KII89678.1 - 0.058 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Abhydrolase_1 PF00561.20 KII89681.1 - 6.3e-15 55.5 0.1 9e-14 51.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII89681.1 - 6.9e-12 46.4 0.1 1.4e-11 45.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KII89681.1 - 2.3e-07 30.8 0.0 1.6e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KII89681.1 - 2.7e-07 30.1 0.0 3.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KII89681.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 KII89681.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_2 PF01674.18 KII89681.1 - 0.0056 16.2 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 2) DUF915 PF06028.11 KII89681.1 - 0.01 15.2 0.1 2.6 7.3 0.1 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 KII89681.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 KII89681.1 - 0.042 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KII89681.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 KII89681.1 - 0.11 12.3 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Steroid_dh PF02544.16 KII89682.1 - 7.8e-39 133.1 0.3 1.2e-38 132.5 0.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.10 KII89682.1 - 0.00092 19.9 0.0 0.0019 18.9 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 KII89682.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 KII89682.1 - 0.055 13.0 0.2 0.075 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Arv1 PF04161.13 KII89684.1 - 2.1e-40 139.1 0.0 3e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family COesterase PF00135.28 KII89685.1 - 2.6e-84 284.0 0.0 4e-84 283.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII89685.1 - 5.5e-09 36.2 0.9 8.5e-08 32.3 0.9 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII89685.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-RING_5 PF14634.6 KII89687.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF2673 PF10880.8 KII89687.1 - 0.2 11.8 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) TMEM151 PF14857.6 KII89688.1 - 0.093 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 TMEM151 family DUF410 PF04190.13 KII89689.1 - 1.9e-74 250.7 0.0 2.6e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSBP1 PF06825.12 KII89690.1 - 3e-21 75.0 4.1 4.2e-21 74.6 4.1 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FdhE PF04216.12 KII89690.1 - 0.015 15.2 0.0 0.016 15.1 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Baculo_PEP_C PF04513.12 KII89690.1 - 0.019 15.0 0.4 0.025 14.6 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 KII89690.1 - 0.076 13.4 1.0 0.12 12.8 1.0 1.4 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 KII89690.1 - 0.11 12.4 0.9 1.5 8.8 0.9 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Ank_5 PF13857.6 KII89691.1 - 1.4e-13 50.7 0.4 0.00038 20.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KII89691.1 - 4.9e-13 48.9 0.4 0.002 18.5 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KII89691.1 - 5e-13 49.5 0.0 3.2e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII89691.1 - 1.7e-11 44.4 0.1 4.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII89691.1 - 2.2e-11 42.9 0.1 0.0013 19.1 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat HMMR_C PF15908.5 KII89691.1 - 0.028 14.7 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Ank_4 PF13637.6 KII89692.1 - 3.7e-18 65.6 0.0 8.5e-12 45.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII89692.1 - 5e-16 58.6 0.0 3.2e-11 43.2 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KII89692.1 - 5e-12 45.7 0.1 9.5e-09 35.3 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KII89692.1 - 2.9e-11 43.8 0.0 3.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII89692.1 - 1e-09 37.8 0.0 5.3e-07 29.4 0.0 2.3 3 0 0 3 3 3 2 Ankyrin repeat Tfb2 PF03849.14 KII89693.1 - 3.2e-136 454.0 0.0 3.8e-136 453.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KII89693.1 - 2.8e-25 88.5 0.1 5.7e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KII89693.1 - 0.0037 17.4 0.0 0.0085 16.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gti1_Pac2 PF09729.9 KII89695.1 - 1.5e-48 165.3 2.4 7.6e-39 133.7 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Terpene_synth_C PF03936.16 KII89698.1 - 2.2e-06 27.2 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KII89698.1 - 0.023 14.8 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal DUF829 PF05705.14 KII89700.1 - 2.3e-37 129.2 0.0 8.9e-37 127.3 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 KII89700.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family FtsJ PF01728.19 KII89701.1 - 9.9e-05 22.5 0.0 0.00027 21.1 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cupin_1 PF00190.22 KII89702.1 - 7.1e-45 152.3 0.1 2.4e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KII89702.1 - 3.6e-30 103.5 0.2 1.1e-14 53.8 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KII89702.1 - 1.2e-10 41.0 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KII89702.1 - 2.9e-08 33.7 0.1 1.7e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 KII89702.1 - 8.9e-05 22.2 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Ectoine_synth PF06339.12 KII89702.1 - 0.0003 21.0 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 2 Ectoine synthase ARD PF03079.14 KII89702.1 - 0.0003 21.0 0.0 0.0098 16.1 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_4 PF08007.12 KII89702.1 - 0.00031 20.3 0.0 0.041 13.4 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein MannoseP_isomer PF01050.18 KII89702.1 - 0.00038 20.4 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_8 PF13621.6 KII89702.1 - 0.012 15.3 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Cupin-like domain Pirin_C PF05726.13 KII89702.1 - 0.15 12.4 0.0 7.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Pirin C-terminal cupin domain RRM_1 PF00076.22 KII89703.1 - 1.8e-21 75.7 0.0 2.3e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 KII89703.1 - 8.7e-06 26.3 44.6 8.7e-06 26.3 44.6 2.1 2 0 0 2 2 2 1 Glycine rich protein family RRM_5 PF13893.6 KII89703.1 - 0.037 13.6 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DcpS_C PF11969.8 KII89706.1 - 2.1e-24 86.2 2.5 2.7e-24 85.9 2.5 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KII89706.1 - 5.9e-08 33.3 7.6 2.2e-07 31.5 7.6 1.8 1 1 0 1 1 1 1 HIT domain CDH PF02611.15 KII89706.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Radical_SAM PF04055.21 KII89706.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.4 1 1 0 1 1 1 0 Radical SAM superfamily UCH PF00443.29 KII89707.1 - 1e-51 175.9 0.1 1.3e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII89707.1 - 7.4e-23 81.6 3.2 3e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KII89707.1 - 4.8e-14 52.4 7.5 4.8e-14 52.4 7.5 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SEO_C PF14577.6 KII89707.1 - 0.23 10.8 2.1 0.26 10.7 0.1 2.0 2 0 0 2 2 2 0 Sieve element occlusion C-terminus Peptidase_C98 PF15499.6 KII89707.1 - 1.3 8.4 8.0 12 5.3 0.3 3.6 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CCDC23 PF15674.5 KII89708.1 - 0.0047 16.9 0.5 0.0077 16.2 0.5 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 Thg1 PF04446.12 KII89709.1 - 1.3e-46 157.7 0.1 2.1e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KII89709.1 - 1.1e-45 154.7 0.1 1.8e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain SbmA_BacA PF05992.12 KII89709.1 - 0.044 13.2 0.9 0.11 11.9 0.2 1.8 2 0 0 2 2 2 0 SbmA/BacA-like family Forkhead PF00250.18 KII89710.1 - 2.8e-29 101.2 0.0 3.1e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain MPS2 PF17060.5 KII89710.1 - 0.016 14.5 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 AAA_35 PF14516.6 KII89710.1 - 0.062 12.1 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 AAA-like domain Hydrolase_4 PF12146.8 KII89711.1 - 1.2e-16 60.8 0.0 9.7e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KII89711.1 - 1.3e-11 44.6 0.0 1.3e-10 41.4 0.1 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KII89711.1 - 1.3e-09 39.0 1.0 1.7e-09 38.6 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII89711.1 - 2.4e-08 33.9 0.0 0.00046 19.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII89711.1 - 4.5e-08 32.8 0.0 0.00044 19.8 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KII89711.1 - 1.7e-06 27.8 0.0 0.00066 19.3 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 KII89711.1 - 0.00018 20.3 0.1 0.095 11.4 0.0 2.7 2 1 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 KII89711.1 - 0.0036 17.4 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 KII89711.1 - 0.005 16.7 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.16 KII89711.1 - 0.026 14.4 0.0 2.1 8.1 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 KII89711.1 - 0.054 13.4 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 KII89711.1 - 0.082 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_3 PF07859.13 KII89711.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 KII89711.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-C2H2 PF00096.26 KII89712.1 - 1.1e-07 31.9 7.4 0.00046 20.5 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII89712.1 - 0.00016 22.2 11.4 0.0049 17.6 1.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger Vps36-NZF-N PF16988.5 KII89712.1 - 0.0061 15.9 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_6 PF13912.6 KII89712.1 - 0.044 13.8 1.6 11 6.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII89712.1 - 0.21 11.9 4.9 1 9.7 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KII89712.1 - 1.1 9.6 4.0 2.7 8.4 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KII89712.1 - 2.2 8.9 7.9 2.5 8.7 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII89713.1 - 0.0015 19.2 7.5 0.26 12.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KII89713.1 - 0.0018 18.6 7.9 0.14 12.7 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII89713.1 - 0.011 16.1 0.8 0.011 16.1 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Coq4 PF05019.13 KII89714.1 - 1.1e-99 332.2 0.0 1.4e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 zf-C2H2_8 PF15909.5 KII89715.1 - 0.00088 19.5 0.2 0.0016 18.7 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 KII89715.1 - 0.04 14.8 1.2 1.7 9.7 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger IBR PF01485.21 KII89715.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2 PF00096.26 KII89715.1 - 2.3 8.9 4.2 13 6.5 0.4 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-SCNM1 PF15803.5 KII89716.1 - 0.32 10.7 3.0 1.9 8.2 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 Fer4_11 PF13247.6 KII89716.1 - 1.4 9.1 16.0 0.31 11.2 0.6 3.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain Pex14_N PF04695.13 KII89716.1 - 2.8 8.6 17.8 4.1 8.0 17.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 KII89716.1 - 4.9 7.1 15.8 6.9 6.6 15.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) YyzF PF14116.6 KII89716.1 - 5.9 7.0 7.4 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 YyzF-like protein DUF1768 PF08719.11 KII89717.1 - 1.1e-28 100.6 0.0 1.7e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.20 KII89718.1 - 2.2e-14 53.5 0.0 1.5e-09 37.7 0.0 3.0 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 KII89719.1 - 9.2e-34 117.0 0.0 1.2e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_L4 PF00573.22 KII89722.1 - 5.5e-41 140.4 0.8 9e-41 139.7 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KII89722.1 - 2.4e-28 98.0 4.1 2.4e-28 98.0 4.1 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Allene_ox_cyc PF06351.11 KII89723.1 - 0.054 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Terpene_synth_C PF03936.16 KII89723.1 - 0.065 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Pkinase_Tyr PF07714.17 KII89725.1 - 2.8e-32 112.0 0.0 2.9e-30 105.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII89725.1 - 2.2e-25 89.6 0.0 4.7e-24 85.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KII89725.1 - 0.098 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ku PF02735.16 KII89726.1 - 2.1e-35 122.3 0.0 4.7e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KII89726.1 - 7.7e-21 74.8 0.0 1.9e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KII89726.1 - 7.4e-17 61.8 1.8 9.5e-17 61.5 0.5 1.9 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KII89726.1 - 2.3e-09 36.8 0.1 4.2e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 KII89726.1 - 0.035 14.7 0.0 1.1 10.0 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain HeH PF12949.7 KII89726.1 - 0.1 12.4 0.2 0.29 10.9 0.2 1.8 1 1 0 1 1 1 0 HeH/LEM domain F-box-like PF12937.7 KII89727.1 - 0.034 14.0 2.0 0.061 13.2 0.2 2.4 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 KII89728.1 - 0.0077 16.1 0.3 0.017 15.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like DUF1295 PF06966.12 KII89729.1 - 1.3e-39 136.1 4.4 1.1e-38 133.1 4.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) HtrL_YibB PF09612.10 KII89731.1 - 0.0098 15.4 0.0 0.023 14.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) DAO PF01266.24 KII89732.1 - 3.3e-36 125.6 0.2 4.1e-36 125.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII89732.1 - 4e-06 27.0 0.0 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII89732.1 - 4.9e-05 22.6 0.8 0.032 13.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KII89732.1 - 0.00018 20.8 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KII89732.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KII89732.1 - 0.014 14.6 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII89732.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein F-box-like PF12937.7 KII89733.1 - 9.3e-07 28.6 0.4 1.4e-05 24.8 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII89733.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 F-box domain Torus PF16131.5 KII89734.1 - 3.6e-39 133.8 4.0 6e-39 133.1 4.0 1.4 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 KII89734.1 - 2e-06 27.5 0.1 3.3e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KII89734.1 - 0.0016 18.4 0.2 0.0034 17.4 0.2 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1492 PF07374.11 KII89734.1 - 0.18 12.0 0.2 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) zf_CCCH_4 PF18345.1 KII89734.1 - 0.26 11.4 6.6 0.49 10.5 6.6 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KII89734.1 - 2.2 8.3 7.9 4.3 7.4 7.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII89734.1 - 3.2 7.7 9.0 5.5 6.9 9.0 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger WD40 PF00400.32 KII89735.1 - 4.1e-05 24.3 2.8 5.7 8.0 0.2 5.2 3 1 1 4 4 4 2 WD domain, G-beta repeat DUF2415 PF10313.9 KII89735.1 - 0.00033 20.5 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Ge1_WD40 PF16529.5 KII89735.1 - 0.026 13.5 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ABC_membrane PF00664.23 KII89736.1 - 7.7e-40 137.3 9.3 9.7e-40 136.9 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KII89736.1 - 7.9e-33 113.9 0.0 2.5e-32 112.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KII89736.1 - 3.8e-06 26.5 0.4 0.0088 15.5 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KII89736.1 - 2.9e-05 23.9 0.0 8.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KII89736.1 - 0.00067 19.6 0.0 0.024 14.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII89736.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KII89736.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KII89736.1 - 0.03 14.6 0.1 0.098 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KII89736.1 - 0.036 14.0 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 KII89736.1 - 0.04 14.4 0.0 0.4 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KII89736.1 - 0.052 14.0 0.1 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KII89736.1 - 0.082 12.5 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII89736.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase LRR_4 PF12799.7 KII89737.1 - 9.4e-21 73.6 26.4 1.5e-06 28.4 3.4 8.5 6 3 2 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII89737.1 - 4.2e-19 68.1 26.5 7.1e-10 38.5 0.6 8.5 6 4 1 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 KII89737.1 - 4.3e-09 35.7 20.4 1.4 9.2 0.0 8.9 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.33 KII89737.1 - 2.4e-06 27.3 15.2 36 5.4 0.1 9.6 10 1 0 10 10 10 1 Leucine Rich Repeat zf-C2H2_4 PF13894.6 KII89739.1 - 6.2e-05 23.5 9.7 0.00032 21.3 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KII89739.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII89739.1 - 0.0052 17.2 4.4 0.0052 17.2 4.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain CwsA PF10814.8 KII89740.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA zf-H2C2_2 PF13465.6 KII89741.1 - 2.4e-05 24.6 7.9 0.028 14.8 1.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII89741.1 - 0.0011 19.6 18.1 0.1 13.5 0.0 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 KII89741.1 - 0.022 15.0 0.5 11 6.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-met PF12874.7 KII89741.1 - 0.39 11.2 6.8 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KII89741.1 - 0.48 11.1 2.9 0.78 10.4 0.9 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats F-box-like PF12937.7 KII89744.1 - 2.9e-08 33.5 0.0 6.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII89744.1 - 0.18 11.7 1.0 2.9 7.9 1.0 2.7 1 1 0 1 1 1 0 F-box domain Pyr_redox_2 PF07992.14 KII89745.1 - 1.4e-50 172.2 1.6 1.8e-50 171.9 1.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KII89745.1 - 2.6e-18 65.7 0.1 5.6e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 KII89745.1 - 8.3e-11 41.7 0.2 2.8e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII89745.1 - 3.1e-10 40.5 7.8 2.5e-09 37.6 0.9 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KII89745.1 - 7.8e-08 32.8 0.0 3.2e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KII89745.1 - 0.00012 21.3 0.3 0.034 13.3 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KII89745.1 - 0.0039 16.5 0.2 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII89745.1 - 0.0045 15.8 0.5 0.78 8.4 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_7 PF13241.6 KII89745.1 - 0.01 16.3 1.1 0.07 13.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Cys_Met_Meta_PP PF01053.20 KII89746.1 - 1.3e-128 428.8 0.0 1.6e-128 428.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KII89746.1 - 3.4e-16 59.2 0.8 1.3e-15 57.4 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KII89746.1 - 2.2e-05 24.7 0.1 6.5e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DegT_DnrJ_EryC1 PF01041.17 KII89746.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KII89746.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GalKase_gal_bdg PF10509.9 KII89746.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 KII89746.1 - 0.0038 15.8 0.0 0.012 14.2 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KII89746.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase B12-binding PF02310.19 KII89746.1 - 0.13 12.3 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 B12 binding domain zf-HIT PF04438.16 KII89747.1 - 5.7e-07 29.3 10.2 9.9e-07 28.5 10.2 1.4 1 0 0 1 1 1 1 HIT zinc finger HMGL-like PF00682.19 KII89748.1 - 2.8e-80 269.7 0.4 4.9e-80 268.9 0.4 1.4 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 KII89748.1 - 0.055 14.0 0.3 0.11 13.1 0.3 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Tis11B_N PF04553.12 KII89749.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.7 3 0 0 3 3 3 0 Tis11B like protein, N terminus DUF966 PF06136.13 KII89749.1 - 1.7 8.3 8.3 2.3 7.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Response_reg PF00072.24 KII89750.1 - 1.7e-17 63.6 0.0 5.5e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KII89750.1 - 3.5e-16 59.7 0.1 9.5e-16 58.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KII89750.1 - 1.1e-12 47.8 0.1 2.7e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 KII89750.1 - 0.00063 20.1 0.0 0.51 10.7 0.0 2.7 2 0 0 2 2 2 2 GAF domain ATPase_gene1 PF09527.10 KII89750.1 - 0.035 14.3 3.8 0.14 12.3 3.8 2.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter UDG PF03167.19 KII89751.1 - 7.2e-20 71.5 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 KII89752.1 - 0.00044 20.3 3.6 0.00072 19.6 3.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII89752.1 - 0.0014 18.7 1.2 0.0026 17.8 1.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 KII89752.1 - 0.056 13.8 0.2 0.1 12.9 0.2 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family HAP1_N PF04849.13 KII89752.1 - 0.21 10.8 0.3 0.29 10.3 0.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Shugoshin_N PF07558.11 KII89752.1 - 0.43 10.5 2.5 0.55 10.1 0.4 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ERCC3_RAD25_C PF16203.5 KII89754.1 - 6.9e-124 411.9 0.1 1.7e-123 410.7 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KII89754.1 - 2e-37 128.2 0.0 4.4e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII89754.1 - 2.6e-17 63.3 0.0 6.2e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII89754.1 - 1.3e-11 44.8 0.1 5.2e-11 42.9 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KII89754.1 - 1.7e-10 40.2 0.1 2.6e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SF1-HH PF16275.5 KII89755.1 - 7.1e-39 132.6 1.2 1.4e-38 131.6 1.2 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KII89755.1 - 1.2e-11 44.1 8.9 1.5e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KII89755.1 - 1.2e-06 28.4 3.6 0.0028 17.6 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KII89755.1 - 1.6e-06 27.9 0.0 3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.6 KII89755.1 - 0.0063 16.2 7.1 0.43 10.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KII89755.1 - 0.031 14.6 2.6 4 7.9 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-CCHC_6 PF15288.6 KII89755.1 - 0.11 12.3 12.9 0.49 10.3 0.6 3.0 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 KII89755.1 - 0.18 12.2 4.5 0.4 11.1 4.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Prim_Zn_Ribbon PF08273.12 KII89755.1 - 0.25 11.6 3.6 0.59 10.5 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CCHC_2 PF13696.6 KII89755.1 - 4 7.3 9.8 0.38 10.6 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Methyltr_RsmB-F PF01189.17 KII89756.1 - 3.1e-29 102.0 0.0 6e-29 101.1 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Dehydratase_SU PF02287.15 KII89756.1 - 0.0024 18.0 0.6 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Dehydratase small subunit Fibrillarin PF01269.17 KII89756.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Fibrillarin DnaJ_C PF01556.18 KII89757.1 - 3.4e-37 127.8 0.1 4.4e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KII89757.1 - 2e-25 88.7 0.1 3.3e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KII89757.1 - 1.1e-11 44.8 19.8 2e-11 44.1 19.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KII89757.1 - 0.047 13.7 8.6 0.39 10.7 2.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KII89757.1 - 0.1 12.6 8.3 0.64 10.1 1.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon Anti-TRAP PF15777.5 KII89757.1 - 0.27 11.2 19.7 0.16 12.0 5.5 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Coiled PF05710.12 KII89757.1 - 0.53 11.2 0.1 0.53 11.2 0.1 2.3 1 1 1 2 2 2 0 Coiled coil ThuA PF06283.11 KII89758.1 - 8.6e-60 202.5 0.0 1e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation CIA30 PF08547.12 KII89759.1 - 1.2e-24 87.2 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) IMS PF00817.20 KII89760.1 - 7.4e-39 133.1 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KII89760.1 - 1.4e-14 54.8 0.0 5.9e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KII89760.1 - 3.8e-07 29.6 2.9 0.00085 18.9 0.8 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KII89760.1 - 0.048 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif TFIIS_C PF01096.18 KII89760.1 - 0.14 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) 7tm_1 PF00001.21 KII89761.1 - 2.5e-05 23.7 7.3 6e-05 22.5 7.3 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Ras PF00071.22 KII89762.1 - 1.7e-58 196.8 0.2 1.9e-58 196.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII89762.1 - 1.8e-20 73.4 0.0 3e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII89762.1 - 9.6e-09 34.9 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII89762.1 - 2.5e-05 23.9 0.1 5.3e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII89762.1 - 4.5e-05 23.4 0.0 0.092 12.7 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KII89762.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII89762.1 - 0.0043 16.6 0.1 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Ser_hydrolase PF06821.13 KII89762.1 - 0.047 13.6 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 KII89762.1 - 0.074 12.8 1.7 0.72 9.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KII89762.1 - 0.12 11.5 0.5 3 6.9 0.3 2.0 1 1 0 2 2 2 0 G-protein alpha subunit Glyco_hydro_38N PF01074.22 KII89762.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain DEAD PF00270.29 KII89763.1 - 6.3e-38 130.3 0.0 2.3e-37 128.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII89763.1 - 3.1e-23 82.2 0.0 3.3e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII89763.1 - 4.2e-09 36.6 0.0 8.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII89763.1 - 0.0094 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KII89763.1 - 0.1 12.9 1.2 3 8.1 1.2 2.7 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KII89764.1 - 1.2e-68 231.8 31.0 5.6e-38 131.2 14.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII89764.1 - 5.7e-50 169.4 0.0 3.3e-28 98.9 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII89764.1 - 2e-07 30.7 1.2 0.021 14.2 0.1 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII89764.1 - 8.5e-06 26.3 0.3 0.24 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KII89764.1 - 4.2e-05 23.5 0.5 0.11 12.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KII89764.1 - 6.1e-05 23.6 0.2 0.31 11.5 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KII89764.1 - 8.1e-05 22.2 1.3 0.11 12.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KII89764.1 - 0.00015 21.8 2.5 0.04 14.0 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KII89764.1 - 0.0002 21.3 1.7 0.17 11.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII89764.1 - 0.0016 18.1 1.2 1 9.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KII89764.1 - 0.0026 18.0 3.1 0.57 10.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KII89764.1 - 0.0038 16.9 0.2 0.76 9.4 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 KII89764.1 - 0.004 16.9 5.3 0.26 11.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KII89764.1 - 0.0092 15.6 0.3 0.38 10.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KII89764.1 - 0.011 16.0 1.2 5.9 7.1 0.2 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_11 PF13086.6 KII89764.1 - 0.056 13.2 0.1 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII89764.1 - 0.08 13.3 0.1 21 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 KII89764.1 - 0.11 12.2 0.6 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KII89764.1 - 0.11 12.5 2.4 14 5.7 0.1 2.9 3 0 0 3 3 3 0 Dynamin family TsaE PF02367.17 KII89764.1 - 0.11 12.5 0.9 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 KII89764.1 - 0.12 12.2 3.7 35 4.0 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KII89764.1 - 0.13 12.0 2.4 5.3 6.7 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KII89764.1 - 0.16 12.4 4.4 2.2 8.7 0.5 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KII89764.1 - 0.35 10.8 1.6 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KII89764.1 - 0.38 10.3 3.6 0.44 10.1 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KII89764.1 - 0.52 10.4 2.5 0.87 9.6 0.7 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 KII89764.1 - 0.83 9.6 2.8 1.3 8.9 0.3 2.4 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 KII89764.1 - 0.93 8.3 5.5 2.4 7.0 0.5 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 KII89764.1 - 2.2 8.5 4.3 19 5.4 0.3 3.2 3 0 0 3 3 3 0 AAA domain Asp PF00026.23 KII89765.1 - 5.8e-69 232.9 1.4 7.1e-69 232.6 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII89765.1 - 7.2e-11 42.6 1.8 1.1e-08 35.6 1.8 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII89765.1 - 0.0077 16.9 0.1 12 6.6 0.0 3.6 3 0 0 3 3 3 1 Aspartyl protease DLH PF01738.18 KII89766.1 - 5e-19 68.7 0.0 7.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KII89766.1 - 0.00034 19.7 0.0 0.00045 19.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KII89766.1 - 0.026 13.4 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Transposase_21 PF02992.14 KII89767.1 - 4e-08 32.8 0.1 1.9e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 KII89767.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HMG_box PF00505.19 KII89771.1 - 4e-10 40.0 0.0 7.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII89771.1 - 0.014 15.9 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain DUF4712 PF15830.5 KII89771.1 - 4.6 6.9 5.8 12 5.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4712) MOZ_SAS PF01853.18 KII89773.1 - 5.5e-73 244.4 0.0 8.2e-73 243.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KII89773.1 - 2.2e-20 72.0 0.3 2.2e-20 72.0 0.3 2.3 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 KII89773.1 - 1.1e-15 57.2 27.5 1.5e-09 37.6 6.6 3.3 2 1 1 3 3 3 2 PHD-finger zf-RING_7 PF02591.15 KII89773.1 - 0.43 10.8 6.4 4.4 7.6 0.2 3.2 2 1 0 2 2 2 0 C4-type zinc ribbon domain PHD_4 PF16866.5 KII89773.1 - 1.9 8.6 23.3 0.86 9.7 9.5 2.7 1 1 1 2 2 2 0 PHD-finger PHD_2 PF13831.6 KII89773.1 - 3.3 7.3 17.7 0.8 9.3 4.3 3.4 3 0 0 3 3 3 0 PHD-finger Pkinase PF00069.25 KII89775.1 - 9e-49 166.2 0.0 1.4e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89775.1 - 1.6e-17 63.7 0.0 3.8e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII89775.1 - 0.11 12.4 1.6 4 7.3 0.4 2.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family SLATT_fungal PF18142.1 KII89776.1 - 2.6e-18 66.2 0.0 3.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Asp PF00026.23 KII89778.1 - 2.1e-66 224.5 4.7 2.5e-66 224.2 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII89778.1 - 7.6e-09 36.0 4.6 1.1e-07 32.3 4.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ECH_1 PF00378.20 KII89779.1 - 2.9e-22 79.2 0.0 3.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII89779.1 - 7e-08 32.3 0.0 8.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase p450 PF00067.22 KII89780.1 - 8.8e-73 245.6 0.0 1.3e-72 245.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDUFB10 PF10249.9 KII89783.1 - 0.0094 16.4 0.7 0.01 16.4 0.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 DUF1616 PF07760.11 KII89784.1 - 6.2e-05 22.5 0.5 0.00017 21.1 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1616) MitoNEET_N PF10660.9 KII89784.1 - 0.037 14.0 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus WD40 PF00400.32 KII89785.1 - 2.3e-19 69.4 1.2 0.00017 22.3 0.0 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89785.1 - 5.3e-07 29.9 0.0 1.2 9.5 0.0 4.4 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpb5_C PF01191.19 KII89786.1 - 7.8e-33 112.2 0.2 1.5e-32 111.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KII89786.1 - 8.1e-29 100.0 0.0 1.6e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KII89786.1 - 0.00084 19.4 0.0 0.0015 18.5 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease R3H PF01424.22 KII89786.1 - 0.094 12.7 0.0 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 R3H domain Terpene_synth_C PF03936.16 KII89787.1 - 0.00041 19.8 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ABC_membrane PF00664.23 KII89788.1 - 9.1e-55 186.2 31.5 1.1e-27 97.4 16.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII89788.1 - 3.7e-48 163.5 0.0 9.5e-28 97.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KII89788.1 - 4.2e-07 30.5 0.1 0.011 16.1 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 KII89788.1 - 3.2e-06 26.8 3.9 0.0067 15.9 1.4 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KII89788.1 - 1.3e-05 25.2 0.5 0.045 13.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KII89788.1 - 0.0001 22.2 1.1 1.8 8.3 0.0 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KII89788.1 - 0.00018 21.5 0.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KII89788.1 - 0.0012 18.5 0.3 2.3 8.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KII89788.1 - 0.0084 15.7 0.5 0.61 9.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KII89788.1 - 0.011 16.0 0.8 3 8.1 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 KII89788.1 - 0.031 13.8 0.2 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KII89788.1 - 0.037 14.5 0.0 16 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KII89788.1 - 0.041 14.1 0.7 9.6 6.4 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KII89788.1 - 0.054 13.2 0.1 0.76 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KII89788.1 - 0.065 13.4 0.6 16 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KII89788.1 - 0.076 12.9 0.4 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Adeno_IVa2 PF02456.15 KII89788.1 - 0.099 11.4 0.2 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 KII89788.1 - 0.16 11.2 0.7 2.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KII89788.1 - 0.16 11.8 0.4 0.82 9.5 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KII89788.1 - 0.17 11.9 5.3 2.9 7.9 0.3 2.5 2 0 0 2 2 2 0 Dynamin family Pex14_N PF04695.13 KII89788.1 - 0.36 11.5 1.4 0.7 10.5 1.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF87 PF01935.17 KII89788.1 - 7.4 6.6 5.3 1.7 8.7 0.8 2.2 3 0 0 3 3 3 0 Helicase HerA, central domain C2 PF00168.30 KII89789.1 - 7.8e-11 42.2 0.0 2.2e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 C2 domain SPX PF03105.19 KII89789.1 - 0.12 12.3 3.9 0.16 11.8 3.9 1.2 1 0 0 1 1 1 0 SPX domain p450 PF00067.22 KII89790.1 - 4.9e-71 239.9 0.0 7.2e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII89791.1 - 2.5e-76 257.3 0.0 3.4e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KII89792.1 - 0.003 17.4 0.3 0.0083 16.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII89793.1 - 0.015 15.1 0.6 0.047 13.6 0.6 1.9 1 0 0 1 1 1 0 F-box-like Ku PF02735.16 KII89794.1 - 1.2e-31 110.0 0.0 4.5e-31 108.1 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KII89794.1 - 4.2e-21 75.7 0.0 1e-20 74.4 0.0 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KII89794.1 - 3.6e-17 62.8 0.7 9e-17 61.6 0.7 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KII89794.1 - 4.3e-09 35.9 0.1 4.3e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 KII89794.1 - 0.11 12.3 0.2 0.3 10.8 0.2 1.8 1 1 0 1 1 1 0 HeH/LEM domain Frag1 PF10277.9 KII89796.1 - 1.6e-36 125.9 11.1 1.8e-36 125.7 11.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2070 PF09843.9 KII89796.1 - 0.17 10.1 4.3 0.24 9.7 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DSBA PF01323.20 KII89801.1 - 6.4e-26 91.3 0.0 8.2e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 KII89801.1 - 0.013 15.6 0.4 0.046 13.8 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin domain p450 PF00067.22 KII89803.1 - 9.7e-67 225.7 0.0 1.9e-66 224.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII89804.1 - 1.1e-71 241.9 0.0 1.7e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YcaO PF02624.16 KII89804.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Plavaka PF18759.1 KII89805.1 - 7.8e-128 426.3 0.0 1.1e-127 425.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KII89805.1 - 6.7 7.8 9.7 0.85 10.6 4.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.7 KII89807.1 - 3.5e-21 75.6 0.0 1.3e-09 38.5 0.0 4.8 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII89807.1 - 7.1e-16 58.4 6.8 0.024 15.2 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII89807.1 - 6e-15 55.1 2.8 0.00042 20.6 0.0 5.7 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII89807.1 - 9.1e-15 53.3 1.2 0.0011 19.3 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KII89807.1 - 3.6e-13 49.3 2.8 0.00085 19.7 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat SesA PF17107.5 KII89807.1 - 0.12 12.6 0.0 0.44 10.7 0.0 2.0 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TAP_C PF03943.13 KII89808.1 - 2.6e-14 52.6 0.0 7.6e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 KII89808.1 - 5.8e-05 22.7 0.1 9.6e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KII89808.1 - 0.00012 22.4 6.8 0.00047 20.5 2.0 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KII89808.1 - 0.00022 21.8 0.0 0.42 11.2 0.0 2.3 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KII89808.1 - 0.0037 17.0 4.4 0.026 14.3 3.2 2.8 1 1 1 2 2 2 1 Leucine rich repeat UBA_4 PF14555.6 KII89808.1 - 0.062 13.1 0.9 0.18 11.7 0.0 2.2 3 0 0 3 3 3 0 UBA-like domain MFS_1 PF07690.16 KII89810.1 - 1.1e-34 119.9 61.6 2.4e-30 105.7 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII89810.1 - 1.8e-06 27.1 19.9 1.7e-05 23.9 19.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII89811.1 - 1.1e-26 93.7 55.6 2.6e-25 89.1 30.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII89811.1 - 0.064 12.1 26.9 0.58 8.9 26.9 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter ATP_synth_reg PF14960.6 KII89811.1 - 0.9 9.1 2.4 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 ATP synthase regulation PagP PF07017.11 KII89812.1 - 0.041 13.3 0.1 0.045 13.2 0.1 1.1 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP SPT2 PF08243.11 KII89813.1 - 1.1e-18 67.8 12.1 1.1e-18 67.8 12.1 4.3 2 1 2 4 4 4 1 SPT2 chromatin protein RRM_1 PF00076.22 KII89814.1 - 7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPA PF08616.10 KII89815.1 - 5.5e-05 23.1 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 KII89815.1 - 0.00011 22.6 0.0 0.00024 21.6 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 KII89815.1 - 0.091 12.7 0.1 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 DENN (AEX-3) domain Pkinase PF00069.25 KII89818.1 - 2.9e-26 92.4 0.0 3.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII89818.1 - 2.3e-12 46.7 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII89818.1 - 1.2e-08 34.2 0.0 1.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII89818.1 - 0.0003 20.8 0.0 0.72 9.7 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family PalH PF08733.10 KII89819.1 - 0.71 8.8 8.7 6.9 5.6 8.7 2.0 1 1 0 1 1 1 0 PalH/RIM21 DUF5484 PF17583.2 KII89822.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5484) DUF4381 PF14316.6 KII89822.1 - 1.3 9.3 5.9 2.4 8.4 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Plavaka PF18759.1 KII89824.1 - 5.8e-20 71.8 1.0 9.8e-20 71.0 1.0 1.4 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KII89826.1 - 5.3e-77 259.2 0.3 6.2e-77 259.0 0.3 1.0 1 0 0 1 1 1 1 Plavaka transposase Plavaka PF18759.1 KII89827.1 - 3e-23 82.5 0.0 3.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase MFS_1 PF07690.16 KII89830.1 - 8e-16 57.9 28.1 8e-16 57.9 28.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ALMT PF11744.8 KII89830.1 - 0.23 10.3 0.4 5.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Sterol-sensing PF12349.8 KII89832.1 - 0.067 13.0 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Acetate_kinase PF00871.17 KII89835.1 - 1.3e-83 280.9 0.0 3.2e-83 279.6 0.0 1.6 1 1 0 1 1 1 1 Acetokinase family Anth_synt_I_N PF04715.13 KII89835.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region XFP_N PF09364.10 KII89836.1 - 2.7e-151 503.5 0.0 3.6e-151 503.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KII89836.1 - 3.3e-78 261.8 0.0 5.6e-78 261.0 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KII89836.1 - 4e-77 257.9 0.0 6.7e-77 257.2 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 KII89836.1 - 0.0038 17.0 0.4 0.0091 15.8 0.4 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p450 PF00067.22 KII89837.1 - 2.7e-66 224.2 0.0 6.9e-66 222.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 TTRAP PF14203.6 KII89837.1 - 0.026 14.5 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Fasciclin PF02469.22 KII89837.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Fasciclin domain FA_hydroxylase PF04116.13 KII89841.1 - 4.3e-22 78.9 20.4 4.3e-22 78.9 20.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CDC45 PF02724.14 KII89842.1 - 4.4 5.5 4.4 6 5.0 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Vps39_1 PF10366.9 KII89843.1 - 4.4e-28 97.7 1.0 1.6e-27 95.9 0.1 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KII89843.1 - 2.5e-23 82.6 0.2 5.7e-23 81.4 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KII89843.1 - 1.3e-15 57.5 1.2 8.1e-11 42.0 0.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KII89843.1 - 1.2e-11 44.7 0.0 4.9e-10 39.5 0.0 3.0 2 1 0 2 2 2 1 CNH domain TPR_19 PF14559.6 KII89843.1 - 0.015 15.8 0.0 0.015 15.8 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KII89843.1 - 0.051 13.4 4.6 11 6.0 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40_like PF17005.5 KII89843.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 WD40-like domain TPR_14 PF13428.6 KII89843.1 - 0.39 11.6 4.6 36 5.5 0.3 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII89843.1 - 2.9 8.6 9.6 48 4.7 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 KII89844.1 - 1.4e-18 66.8 8.2 0.00056 20.7 0.2 5.8 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII89844.1 - 3.8e-09 36.7 0.0 0.046 14.0 0.0 5.1 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII89844.1 - 0.00047 20.1 0.1 0.073 12.9 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LEM PF03020.15 KII89844.1 - 0.0095 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 LEM domain WD40_like PF17005.5 KII89844.1 - 0.038 13.3 0.0 0.65 9.3 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KII89844.1 - 0.073 12.0 0.0 1.9 7.3 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KII89844.1 - 0.12 10.7 0.0 1.7 6.8 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz ADH_zinc_N_2 PF13602.6 KII89845.1 - 1.2e-18 68.4 0.0 2.3e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KII89845.1 - 8e-15 55.0 0.1 1.7e-14 53.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII89845.1 - 5.8e-12 45.5 0.1 1.9e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KII89845.1 - 0.052 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AAA_11 PF13086.6 KII89845.1 - 0.06 13.1 0.1 0.081 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF1295 PF06966.12 KII89846.1 - 2.2e-46 158.3 0.1 2.8e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KII89846.1 - 0.00016 22.0 0.1 0.00054 20.3 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KII89846.1 - 0.00058 18.7 0.1 0.0012 17.7 0.1 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KII89846.1 - 0.019 15.4 0.0 0.061 13.7 0.0 2.0 1 0 0 1 1 1 0 Phospholipid methyltransferase Steroid_dh PF02544.16 KII89846.1 - 0.083 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase p450 PF00067.22 KII89847.1 - 4e-68 230.2 0.0 4.9e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_synth PF06684.11 KII89847.1 - 0.14 11.6 0.0 0.45 10.0 0.0 1.8 1 1 1 2 2 2 0 Amino acid synthesis SIR2 PF02146.17 KII89849.1 - 6.1e-28 97.9 0.2 2.2e-19 70.1 0.0 3.0 2 1 0 2 2 2 2 Sir2 family DUF2457 PF10446.9 KII89849.1 - 3.2 6.8 17.6 7.8 5.5 17.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DSS1_SEM1 PF05160.13 KII89850.1 - 2.1e-24 85.3 7.1 2.9e-24 84.9 7.1 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.24 KII89851.1 - 6.6e-32 111.0 32.0 4.5e-18 65.4 10.9 2.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KII89851.1 - 9.5e-18 64.2 35.3 9.5e-18 64.2 35.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily APG6_N PF17675.1 KII89852.1 - 0.0076 16.8 4.3 0.014 15.9 4.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Alpha-amylase PF00128.24 KII89853.1 - 6.7e-11 42.3 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KII89853.1 - 1.6e-06 28.5 0.1 6.2e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.6 KII89853.1 - 0.064 12.3 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain COesterase PF00135.28 KII89856.1 - 8.2e-88 295.5 0.0 1e-87 295.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII89856.1 - 1.6e-07 31.4 0.0 3.4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1168 PF06658.12 KII89856.1 - 0.18 11.6 0.2 0.29 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Amidohydro_3 PF07969.11 KII89857.1 - 1.7e-17 64.1 6.0 6.3e-10 39.1 0.0 4.2 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 KII89857.1 - 2e-14 53.7 0.0 1.8e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family HIT PF01230.23 KII89858.1 - 7.5e-22 77.9 0.1 1e-21 77.4 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KII89858.1 - 2.1e-11 44.3 0.1 2.8e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KII89858.1 - 0.073 12.9 0.7 0.21 11.4 0.7 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 MBOAT_2 PF13813.6 KII89859.1 - 9.4e-16 57.9 2.4 9.4e-16 57.9 2.4 2.2 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family NPR3 PF03666.13 KII89860.1 - 1.1e-92 311.3 2.5 2.8e-70 237.4 0.0 2.6 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KII89860.1 - 0.037 12.8 0.0 0.091 11.5 0.0 1.6 2 0 0 2 2 2 0 Nitrogen permease regulator 2 AvrL567-A PF11529.8 KII89860.1 - 0.076 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Melampsora lini avirulence protein AvrL567-A Epimerase PF01370.21 KII89861.1 - 3.1e-21 75.9 0.0 4.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII89861.1 - 5.5e-13 49.0 0.0 3.1e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII89861.1 - 1.4e-10 41.3 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII89861.1 - 4.3e-09 35.8 0.0 5.5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KII89861.1 - 1.8e-05 24.5 0.1 2.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KII89861.1 - 4.7e-05 22.6 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 KII89861.1 - 0.00014 22.0 0.2 0.00022 21.3 0.2 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KII89861.1 - 0.00043 19.8 0.1 0.00054 19.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KII89861.1 - 0.00054 20.2 0.1 0.0013 19.0 0.1 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain HTH_8 PF02954.19 KII89861.1 - 0.011 15.5 0.4 0.59 10.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family TrkA_N PF02254.18 KII89861.1 - 0.033 14.4 0.1 0.069 13.4 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.23 KII89861.1 - 0.058 13.5 0.1 0.087 12.9 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KII89861.1 - 0.061 13.9 0.1 0.2 12.3 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KII89861.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SAD_SRA PF02182.17 KII89862.1 - 5.4e-45 152.9 2.2 2.4e-44 150.8 0.3 2.1 2 0 0 2 2 2 1 SAD/SRA domain Mucin PF01456.17 KII89862.1 - 1.4 8.9 6.1 3.4 7.6 4.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Peptidase_S15 PF02129.18 KII89869.1 - 3.8e-10 39.8 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KII89869.1 - 4.5e-10 39.6 0.1 2.9e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII89869.1 - 9.8e-08 32.9 0.3 1e-05 26.3 0.7 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII89869.1 - 2.3e-07 30.3 0.0 1.1e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII89869.1 - 0.008 15.7 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family VirJ PF06057.11 KII89869.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.7 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) SAD_SRA PF02182.17 KII89870.1 - 1.9e-45 154.4 0.4 2.4e-45 154.0 0.4 1.1 1 0 0 1 1 1 1 SAD/SRA domain Pep1_7 PF17232.2 KII89870.1 - 0.76 10.3 6.2 0.36 11.3 2.3 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 SAD_SRA PF02182.17 KII89871.1 - 2.9e-41 140.8 0.2 4.1e-39 133.8 0.2 2.4 1 1 0 1 1 1 1 SAD/SRA domain RBB1NT PF08169.11 KII89871.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Cation_ATPase_C PF00689.21 KII89872.1 - 8.6e-48 162.4 8.3 8.6e-48 162.4 8.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KII89872.1 - 1.1e-37 129.3 0.4 1.1e-37 129.3 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KII89872.1 - 1.7e-23 82.5 0.0 4.9e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KII89872.1 - 7.1e-16 59.1 1.0 1e-14 55.3 1.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KII89872.1 - 2.4e-08 33.6 0.3 9.1e-08 31.7 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII89872.1 - 3.8e-05 23.6 0.4 0.0044 16.8 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Methyltransf_25 PF13649.6 KII89875.1 - 6.7e-05 23.5 0.0 0.0068 17.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Pkinase PF00069.25 KII89876.1 - 2.9e-50 171.1 0.0 8.5e-43 146.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII89876.1 - 6.7e-25 87.9 0.1 1.8e-21 76.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KII89876.1 - 0.00027 20.9 0.2 0.056 13.4 0.1 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII89876.1 - 0.0007 18.5 1.2 0.00089 18.1 0.0 1.6 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KII89876.1 - 0.0047 16.3 0.0 0.11 11.8 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Baculo_PEP_C PF04513.12 KII89877.1 - 0.016 15.3 3.1 0.039 14.0 3.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4686 PF15742.5 KII89877.1 - 0.07 12.3 30.8 0.16 11.1 30.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) CEP63 PF17045.5 KII89877.1 - 0.32 10.9 32.3 0.79 9.6 32.3 1.7 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa EzrA PF06160.12 KII89877.1 - 1.5 6.9 27.6 0.0044 15.3 13.2 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 KII89877.1 - 2.1 7.2 34.9 0.055 12.3 18.4 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein ORF6C PF10552.9 KII89877.1 - 2.7 8.1 16.1 0.53 10.4 8.0 3.0 1 1 1 2 2 2 0 ORF6C domain Cep57_MT_bd PF06657.13 KII89877.1 - 3.8 8.0 23.6 0.87 10.1 3.3 3.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Macoilin PF09726.9 KII89877.1 - 4.2 5.8 28.3 1.5 7.3 25.3 1.9 1 1 0 1 1 1 0 Macoilin family ADIP PF11559.8 KII89877.1 - 5 7.2 34.2 0.68 10.0 19.7 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 KII89877.1 - 5.9 6.7 27.5 0.12 12.2 12.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Cob_adeno_trans PF01923.18 KII89877.1 - 9.5 6.3 15.8 7.2 6.7 9.6 3.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TolA_bind_tri PF16331.5 KII89877.1 - 9.8 6.3 33.1 0.49 10.5 4.4 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation SH3_9 PF14604.6 KII89878.1 - 0.0096 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SNN_transmemb PF09049.10 KII89878.1 - 0.045 13.7 1.4 0.084 12.8 1.4 1.4 1 0 0 1 1 1 0 Stannin transmembrane NmrA PF05368.13 KII89879.1 - 2.6e-33 115.5 0.0 3.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII89879.1 - 1.8e-08 34.5 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII89879.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acyl-CoA_dh_1 PF00441.24 KII89880.1 - 2.5e-30 105.6 2.9 3.7e-30 105.1 2.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII89880.1 - 8e-18 64.4 0.5 1.7e-17 63.4 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KII89880.1 - 1.6e-15 57.0 0.0 3.9e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KII89880.1 - 4.4e-10 40.2 0.1 1.7e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KII89880.1 - 5.8e-07 29.9 1.7 9.7e-07 29.1 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LysM PF01476.20 KII89881.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain APG17 PF04108.12 KII89882.1 - 9.4e-84 281.8 15.8 1.1e-83 281.6 15.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Aldo_ket_red PF00248.21 KII89882.1 - 0.024 13.9 0.5 0.04 13.1 0.5 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family Spectrin_like PF18373.1 KII89882.1 - 0.032 14.3 11.6 0.46 10.6 0.1 3.5 4 0 0 4 4 4 0 Spectrin like domain FTO_CTD PF12934.7 KII89882.1 - 0.56 9.9 8.0 0.8 9.5 0.8 3.0 2 1 1 3 3 3 0 FTO C-terminal domain UPF0184 PF03670.13 KII89882.1 - 1.7 9.1 9.6 2.4 8.6 0.3 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Spc7 PF08317.11 KII89882.1 - 4.1 6.2 16.2 1.6 7.6 12.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Spidroin_N PF16763.5 KII89882.1 - 5.7 7.0 6.9 6.1 6.9 0.6 3.2 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF3450 PF11932.8 KII89882.1 - 7 5.9 22.8 1.5 8.1 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Amnionless PF14828.6 KII89883.1 - 0.016 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless Glycophorin_A PF01102.18 KII89883.1 - 0.041 14.1 0.3 0.041 14.1 0.3 2.5 3 0 0 3 3 3 0 Glycophorin A Shisa PF13908.6 KII89883.1 - 0.52 10.5 3.0 0.35 11.1 0.3 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Acyl-CoA_dh_1 PF00441.24 KII89884.1 - 8.7e-29 100.7 0.2 1.3e-28 100.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII89884.1 - 1.9e-19 69.6 0.8 4.1e-19 68.6 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KII89884.1 - 1.4e-18 66.8 0.0 4.2e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KII89884.1 - 6.9e-14 52.5 0.0 1.5e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KII89884.1 - 0.00038 20.7 0.0 0.00079 19.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 KII89885.1 - 6.7e-09 35.2 0.5 1.3e-08 34.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII89885.1 - 0.0012 19.0 11.8 0.0021 18.1 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 KII89886.1 - 3.3e-56 191.0 0.0 1.1e-55 189.3 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III Actin PF00022.19 KII89887.1 - 2.5e-86 289.9 0.0 9.8e-85 284.6 0.0 2.0 1 1 0 1 1 1 1 Actin NAD_binding_10 PF13460.6 KII89888.1 - 1.6e-09 37.9 0.3 3.3e-09 36.9 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII89888.1 - 7e-07 29.0 0.0 9.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KII89888.1 - 5.4e-05 22.8 0.0 9.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII89888.1 - 0.00012 21.4 0.1 0.0003 20.1 0.1 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KII89888.1 - 0.00014 22.3 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII89888.1 - 0.0034 16.4 0.0 0.024 13.7 0.0 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KII89888.1 - 0.048 14.2 0.1 0.14 12.8 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KII89888.1 - 0.086 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KII89889.1 - 1.9e-09 37.7 0.7 3.2e-09 36.9 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII89889.1 - 1.1e-06 28.3 0.2 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KII89889.1 - 2.7e-06 27.0 0.1 2.2e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KII89889.1 - 6.6e-05 23.3 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KII89889.1 - 7.3e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein F420_oxidored PF03807.17 KII89889.1 - 0.0069 16.9 0.2 0.016 15.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KII89889.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 KII89889.1 - 0.11 13.2 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Ala_racemase_N PF01168.20 KII89890.1 - 1.2e-18 67.6 0.0 2.3e-18 66.6 0.0 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hydrolase_like PF13242.6 KII89890.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like NUC130_3NT PF08158.12 KII89890.1 - 0.17 12.2 0.0 0.73 10.2 0.0 1.9 2 0 0 2 2 2 0 NUC130/3NT domain NAD_binding_10 PF13460.6 KII89891.1 - 1.6e-08 34.7 0.3 3e-08 33.8 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII89891.1 - 1.8e-07 30.9 0.1 4e-07 29.8 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 KII89891.1 - 0.00012 21.7 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII89891.1 - 0.0016 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KII89891.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII89891.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ufm1 PF03671.14 KII89891.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein NAD_binding_10 PF13460.6 KII89892.1 - 6.4e-06 26.2 0.1 1.1e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII89892.1 - 1.7e-05 24.5 0.2 4e-05 23.3 0.1 1.7 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.21 KII89892.1 - 2.9e-05 23.7 0.0 0.091 12.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII89892.1 - 0.00057 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KII89892.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII89892.1 - 0.078 12.0 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family C2 PF00168.30 KII89893.1 - 8.5e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain Alpha-L-AF_C PF06964.12 KII89894.1 - 1.7e-31 109.6 0.0 2.8e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KII89894.1 - 0.0034 17.4 0.2 0.0094 15.9 0.2 1.7 1 1 0 1 1 1 1 Glycoside hydrolase family 44 Glyco_hydro_30C PF17189.4 KII89894.1 - 0.0057 16.9 0.0 0.017 15.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_79n PF03662.14 KII89894.1 - 0.0082 15.1 0.2 0.018 14.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 79, N-terminal domain Sugar_tr PF00083.24 KII89895.1 - 3.5e-100 336.0 21.5 6.8e-100 335.0 21.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII89895.1 - 4.2e-28 98.3 40.2 5.4e-26 91.4 17.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KII89896.1 - 1.4e-08 34.5 0.6 3.5e-08 33.2 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KII89896.1 - 0.26 11.3 3.4 2.2 8.3 0.6 3.4 3 2 0 3 3 3 0 F-box-like domain adh_short PF00106.25 KII89897.1 - 5.5e-88 293.5 20.5 5.8e-45 153.2 7.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII89897.1 - 4.5e-67 226.0 19.1 2.6e-34 118.8 7.6 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII89897.1 - 5.5e-31 107.9 11.8 9.5e-17 61.5 2.1 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KII89897.1 - 0.00011 21.6 3.1 0.015 14.7 0.3 3.1 2 1 1 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KII89897.1 - 0.00034 20.5 10.1 0.049 13.5 1.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII89897.1 - 0.0021 17.5 1.9 0.037 13.4 0.1 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phage_portal_2 PF05136.13 KII89897.1 - 0.028 13.6 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Phage portal protein, lambda family DUF543 PF04418.12 KII89897.1 - 0.03 14.3 4.4 1.3 9.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Shikimate_DH PF01488.20 KII89897.1 - 0.03 14.4 1.9 6.8 6.8 0.2 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CstA_5TM PF13722.6 KII89897.1 - 0.12 12.7 3.6 1.5 9.2 0.2 2.7 2 1 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA Ldh_1_N PF00056.23 KII89897.1 - 0.45 10.6 6.2 7.2 6.7 0.7 2.4 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PglL_A PF15864.5 KII89897.1 - 1.1 9.0 8.2 7.4 6.4 1.1 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Cyclin_N PF00134.23 KII89899.1 - 7.6e-43 145.3 0.2 1.4e-41 141.2 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KII89899.1 - 1.9e-24 86.1 0.0 3.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain BRI3BP PF14965.6 KII89899.1 - 0.062 12.8 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 G-patch PF01585.23 KII89901.1 - 1.3e-08 34.6 0.6 2.2e-08 33.9 0.6 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 KII89901.1 - 7.8e-08 32.6 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KII89901.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain XLF PF09302.11 KII89902.1 - 1.3e-08 35.2 0.5 1.9e-08 34.7 0.5 1.2 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Hva1_TUDOR PF11160.8 KII89904.1 - 5.7e-07 29.6 1.0 7.3e-05 22.9 1.0 2.1 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain DUF1918 PF08940.11 KII89904.1 - 0.021 14.4 0.0 0.027 14.1 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1918) TOM13 PF08219.11 KII89905.1 - 1.1e-12 47.7 0.0 2.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Outer membrane protein TOM13 Na_Ca_ex PF01699.24 KII89906.1 - 2.8e-36 124.8 42.1 6.3e-19 68.4 15.9 2.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein SUD-M PF11633.8 KII89908.1 - 0.068 12.9 0.0 0.068 12.9 0.0 1.0 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain F-box-like PF12937.7 KII89910.1 - 0.00027 20.8 0.9 0.00097 19.0 0.9 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII89910.1 - 0.013 15.9 0.1 0.45 11.0 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KII89910.1 - 0.16 12.1 0.0 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 KII89911.1 - 0.0029 18.0 1.1 0.1 13.0 0.0 3.7 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII89911.1 - 0.008 16.1 1.9 0.029 14.3 1.9 2.1 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 KII89911.1 - 0.02 14.9 0.7 9.6 6.5 0.1 4.6 6 0 0 6 6 6 0 Leucine Rich repeat FAD_binding_3 PF01494.19 KII89912.1 - 6.1e-89 298.7 0.0 9e-89 298.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KII89912.1 - 9.7e-43 146.1 0.0 1.9e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KII89912.1 - 0.00039 19.7 0.0 0.0015 17.8 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII89912.1 - 0.00098 17.9 0.1 0.0016 17.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KII89912.1 - 0.002 17.1 0.1 0.0057 15.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KII89912.1 - 0.0035 17.5 0.1 0.0082 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII89912.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KII89912.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KII89912.1 - 0.05 12.7 0.3 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KII89912.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KII89912.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KII89912.1 - 0.094 11.8 0.1 0.23 10.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KII89912.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Transketolase_C PF02780.20 KII89912.1 - 0.16 11.8 0.0 0.56 10.1 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain Erg28 PF03694.13 KII89913.1 - 1.5e-40 138.0 6.5 1.9e-40 137.7 6.5 1.1 1 0 0 1 1 1 1 Erg28 like protein MaoC_dehydratas PF01575.19 KII89915.1 - 6.7e-32 109.7 0.0 1.2e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KII89915.1 - 1.8e-06 28.1 0.0 5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF2190 PF09956.9 KII89915.1 - 0.033 14.7 0.0 0.091 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) DUF4078 PF13300.6 KII89916.1 - 1.4e-16 60.6 23.4 3.4e-15 56.1 17.6 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) Lactamase_B PF00753.27 KII89917.1 - 1.1e-05 25.6 0.3 1.4e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ank_5 PF13857.6 KII89918.1 - 4.1e-13 49.3 0.3 6.1e-11 42.3 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KII89918.1 - 1.8e-12 47.5 0.3 9.8e-06 26.0 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII89918.1 - 3.3e-09 37.2 0.0 2.3e-08 34.5 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KII89918.1 - 4.1e-06 26.7 0.1 0.00015 21.9 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeat Ank PF00023.30 KII89918.1 - 5.6e-06 26.6 0.3 0.00026 21.3 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeat CCDC24 PF15669.5 KII89918.1 - 0.0003 20.7 0.1 0.00046 20.1 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family 7tm_2 PF00002.24 KII89919.1 - 0.0064 15.8 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) F-box-like PF12937.7 KII89919.1 - 0.019 14.8 2.9 0.036 14.0 0.1 2.7 2 1 0 2 2 2 0 F-box-like 7tm_2 PF00002.24 KII89921.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) F-box-like PF12937.7 KII89921.1 - 0.014 15.2 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like ThiS PF02597.20 KII89924.1 - 0.00015 22.3 0.0 0.00017 22.2 0.0 1.1 1 0 0 1 1 1 1 ThiS family TPK_catalytic PF04263.16 KII89925.1 - 5.2e-38 129.8 0.0 6.9e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KII89925.1 - 1.2e-20 72.9 0.1 1.9e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CS PF04969.16 KII89926.1 - 0.00017 22.5 0.0 0.00048 21.1 0.0 1.7 1 0 0 1 1 1 1 CS domain Terpene_synth_C PF03936.16 KII89927.1 - 0.011 15.1 0.3 0.032 13.6 0.3 1.7 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Endonuc-MspI PF09208.10 KII89927.1 - 0.17 11.2 0.0 0.65 9.3 0.0 1.7 1 1 1 2 2 2 0 Restriction endonuclease MspI GATA PF00320.27 KII89928.1 - 1e-13 50.6 4.5 2.3e-13 49.5 4.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KII89928.1 - 0.056 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 KII89928.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.6 KII89928.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAP1 PF08601.10 KII89930.1 - 1.6 8.3 13.5 2 8.1 13.5 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 KII89930.1 - 9 4.7 7.8 10 4.5 7.8 1.0 1 0 0 1 1 1 0 Macoilin family PRMT5_TIM PF17285.2 KII89931.1 - 7.9e-71 238.3 0.1 1.1e-70 237.8 0.1 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KII89931.1 - 8.5e-64 214.5 0.0 1.8e-63 213.5 0.0 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KII89931.1 - 2.7e-57 193.5 0.0 3.8e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 KII89931.1 - 0.08 13.7 0.0 0.24 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Molybdopterin_N PF18364.1 KII89931.1 - 0.093 12.8 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Met_10 PF02475.16 KII89931.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein LRR_4 PF12799.7 KII89932.1 - 1.4e-33 114.3 38.7 3.8e-07 30.3 1.7 6.9 5 1 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII89932.1 - 1.2e-25 89.0 39.9 2.4e-11 43.2 4.1 6.8 2 1 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 KII89932.1 - 2.1e-24 86.0 13.9 3.1e-11 43.1 2.1 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KII89932.1 - 6.4e-09 35.1 27.2 0.73 10.6 0.2 10.0 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 KII89932.1 - 1.2e-05 24.9 26.4 7.1 7.0 0.0 8.9 10 1 1 11 11 11 4 Leucine Rich repeat LRR_5 PF13306.6 KII89932.1 - 0.085 12.8 0.1 0.76 9.7 0.0 2.2 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_12 PF18837.1 KII89932.1 - 4.2 7.1 7.6 7.2 6.4 0.0 3.7 5 0 0 5 5 5 0 Leucine-rich repeat PFK PF00365.20 KII89933.1 - 2.8e-180 597.8 0.2 9.8e-98 327.0 0.1 2.9 2 1 0 2 2 2 2 Phosphofructokinase DUF3421 PF11901.8 KII89935.1 - 3.5e-32 110.8 0.1 1.7e-28 98.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) KilA-N PF04383.13 KII89936.1 - 0.11 12.4 0.0 0.64 9.9 0.0 2.1 1 1 0 1 1 1 0 KilA-N domain Hamartin PF04388.12 KII89936.1 - 0.19 10.4 14.1 0.22 10.2 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein WLM PF08325.10 KII89937.1 - 1.7e-34 119.6 3.3 1.5e-33 116.5 3.3 2.1 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KII89937.1 - 4e-06 26.0 0.7 9.1e-06 24.9 0.7 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KII89937.1 - 6.4e-06 26.4 0.2 2.2e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 Peptidase_M91 PF14891.6 KII89937.1 - 0.036 14.4 0.2 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Effector protein SprT-like PF10263.9 KII89937.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 SprT-like family Nucleo_P87 PF07267.11 KII89937.1 - 2.8 6.7 3.8 4.3 6.1 3.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 APH PF01636.23 KII89938.1 - 0.026 14.5 1.7 0.54 10.1 0.9 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pet100 PF09803.9 KII89939.1 - 0.1 13.2 1.5 0.14 12.7 1.5 1.2 1 0 0 1 1 1 0 Pet100 QH-AmDH_gamma PF08992.11 KII89939.1 - 0.14 12.1 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Chromo PF00385.24 KII89940.1 - 5.7e-11 42.2 0.1 7e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 KII89944.1 - 3.9e-14 52.2 0.1 4.6e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Transposase_21 PF02992.14 KII89951.1 - 1.3e-06 27.8 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Auto_anti-p27 PF06677.12 KII89951.1 - 0.075 13.2 2.0 7 6.9 0.1 3.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4218 PF13960.6 KII89951.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Asp PF00026.23 KII89952.1 - 6.2e-47 160.5 0.8 9.7e-47 159.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII89952.1 - 5e-07 30.1 4.0 4e-06 27.2 4.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII89952.1 - 0.00023 21.7 0.7 0.37 11.5 0.5 3.7 2 1 0 2 2 2 2 Aspartyl protease RasGAP PF00616.19 KII89953.1 - 2e-61 207.3 0.2 4.3e-59 199.7 0.0 2.7 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KII89953.1 - 1.4e-37 128.9 0.5 1.4e-37 128.9 0.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Taxilin PF09728.9 KII89953.1 - 0.11 11.7 13.7 0.41 9.8 3.0 3.2 3 0 0 3 3 3 0 Myosin-like coiled-coil protein Na_Ca_ex PF01699.24 KII89956.1 - 1.1e-42 145.6 47.7 1.5e-26 93.1 14.5 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein NPF PF16601.5 KII89956.1 - 0.24 11.8 3.8 8.7 6.8 0.6 2.4 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif SGL PF08450.12 KII89957.1 - 0.0002 21.1 0.0 0.00069 19.3 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KII89957.1 - 0.036 14.2 0.1 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Arylesterase Lactonase PF10282.9 KII89957.1 - 0.039 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BRO1 PF03097.18 KII89959.1 - 5.9e-99 331.5 0.0 1.1e-98 330.6 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KII89959.1 - 7.7e-75 251.9 7.7 7.7e-75 251.9 7.7 1.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Borrelia_orfA PF02414.15 KII89959.1 - 0.25 11.0 3.9 2.4 7.7 0.5 2.2 2 0 0 2 2 2 0 Borrelia ORF-A DnaJ_C PF01556.18 KII89961.1 - 4.4e-27 95.0 0.0 6.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KII89961.1 - 1.1e-25 89.5 4.0 1.8e-25 88.9 4.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KII89961.1 - 5.5e-14 52.3 16.7 8.5e-14 51.7 16.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KII89961.1 - 0.00027 20.8 9.5 0.012 15.6 1.4 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KII89961.1 - 0.002 18.1 4.8 0.85 9.7 1.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KII89961.1 - 0.82 9.3 7.0 0.11 12.1 0.5 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 KII89961.1 - 1.6 8.8 9.7 6.3 6.9 9.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KII89961.1 - 1.9 8.9 11.7 1.2 9.6 0.2 3.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar PhzC-PhzF PF02567.16 KII89962.1 - 6e-36 124.4 0.0 6.8e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KII89962.1 - 0.00031 19.9 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Proline racemase Xpo1 PF08389.12 KII89963.1 - 7.4e-16 58.5 0.0 4.4e-15 56.0 0.0 2.4 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 KII89963.1 - 0.0002 21.4 0.2 0.092 13.0 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KII89963.1 - 0.064 13.8 0.5 71 4.1 0.2 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 KII89963.1 - 0.067 13.6 0.0 3.9 7.9 0.0 3.2 2 0 0 2 2 2 0 HEAT repeats ERAP1_C PF11838.8 KII89963.1 - 0.084 12.4 0.0 0.41 10.1 0.0 2.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Cullin PF00888.22 KII89964.1 - 1.3e-203 678.1 0.0 1.7e-203 677.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KII89964.1 - 9.5e-29 99.2 2.6 3.3e-28 97.5 2.6 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain SecA_SW PF07516.13 KII89964.1 - 0.13 12.3 3.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 0 SecA Wing and Scaffold domain HTH_36 PF13730.6 KII89964.1 - 0.17 11.9 0.0 0.63 10.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Pyr_redox_2 PF07992.14 KII89965.1 - 6.4e-25 88.0 0.0 2.3e-23 82.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII89965.1 - 4.3e-11 43.2 0.0 1.3e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII89965.1 - 0.0036 17.3 0.2 0.085 12.8 0.0 2.7 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KII89965.1 - 0.0043 16.7 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII89965.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII89965.1 - 0.049 13.9 0.0 1.4 9.2 0.0 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KII89965.1 - 0.097 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) F-box-like PF12937.7 KII89966.1 - 1.3e-05 24.9 0.5 3.3e-05 23.7 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII89966.1 - 2.3e-05 24.1 0.5 6e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 F-box domain Apolipoprotein PF01442.18 KII89967.1 - 0.12 12.2 8.9 0.24 11.3 8.9 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Syntaphilin PF15290.6 KII89967.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 Golgi-localised syntaxin-1-binding clamp DUF883 PF05957.13 KII89967.1 - 7.4 7.2 13.5 9 7.0 4.5 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Cellulase PF00150.18 KII89968.1 - 9.1e-15 54.8 1.7 2.2e-14 53.5 1.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ketoacyl-synt PF00109.26 KII89969.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain TFIIA PF03153.13 KII89969.1 - 2.2 8.2 18.3 2.8 7.8 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Colipase PF01114.18 KII89970.1 - 0.034 13.8 1.6 0.08 12.6 1.6 1.6 1 0 0 1 1 1 0 Colipase, N-terminal domain RL10P_insert PF17777.1 KII89971.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P DFF40 PF09230.10 KII89972.1 - 0.0011 18.6 1.2 0.0019 17.8 1.2 1.2 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa Rubrerythrin PF02915.17 KII89972.1 - 0.0059 17.0 2.6 0.013 15.9 2.3 1.7 1 1 0 1 1 1 1 Rubrerythrin BAR_3 PF16746.5 KII89972.1 - 0.44 10.2 4.8 0.75 9.4 4.8 1.3 1 0 0 1 1 1 0 BAR domain of APPL family SARAF PF06682.12 KII89974.1 - 2.6e-67 227.8 0.1 3.2e-67 227.5 0.1 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis OPT PF03169.15 KII89975.1 - 5.1e-135 451.5 20.3 5.9e-135 451.3 20.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3995 PF13160.6 KII89975.1 - 0.017 15.5 0.1 0.017 15.5 0.1 4.0 5 1 1 6 6 6 0 Protein of unknown function (DUF3995) Phage_holin_2_1 PF04971.12 KII89975.1 - 0.088 12.8 10.9 0.35 10.9 0.2 3.3 3 0 0 3 3 3 0 Bacteriophage P21 holin S tRNA-synt_1g PF09334.11 KII89976.1 - 2.3e-135 451.4 0.0 2.8e-135 451.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KII89976.1 - 6.1e-07 29.5 3.7 1.7e-06 28.1 3.7 1.8 1 0 0 1 1 1 1 WHEP-TRS domain Anticodon_1 PF08264.13 KII89976.1 - 9.9e-05 22.3 0.0 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 KII89976.1 - 0.00038 18.8 0.0 0.0019 16.6 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DUF1289 PF06945.13 KII89976.1 - 0.2 11.5 5.1 7.1 6.5 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Mitoc_mL59 PF18126.1 KII89976.1 - 0.21 11.9 0.8 0.51 10.7 0.8 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 C1_1 PF00130.22 KII89976.1 - 0.7 9.8 2.1 1.7 8.6 2.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_15 PF17032.5 KII89976.1 - 0.76 10.6 4.5 0.31 11.8 1.9 1.8 2 0 0 2 2 2 0 zinc-ribbon family Pectate_lyase_3 PF12708.7 KII89977.1 - 1.2e-98 329.2 15.5 3.8e-85 285.1 7.6 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KII89977.1 - 2.4e-10 40.0 1.9 0.00047 19.8 0.2 3.3 2 1 1 3 3 3 2 N terminal extension of bacteriophage endosialidase Asp PF00026.23 KII89978.1 - 1.6e-49 169.0 17.6 4.1e-49 167.7 17.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII89978.1 - 9.3e-08 32.5 9.7 0.0001 22.6 0.3 3.9 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII89978.1 - 0.025 15.2 5.6 0.24 12.1 1.0 2.7 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KII89978.1 - 0.065 13.0 0.5 2.2 8.0 0.5 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal COX5B PF01215.19 KII89980.1 - 1.1e-49 167.5 0.0 1.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KII89980.1 - 0.0048 16.9 0.4 0.0071 16.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-RING_4 PF14570.6 KII89980.1 - 0.13 12.1 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.6 KII89980.1 - 0.16 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ATP-synt_Eps PF04627.13 KII89980.1 - 0.31 11.1 1.7 0.51 10.4 1.7 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain Na_Ca_ex PF01699.24 KII89981.1 - 2.8e-31 108.5 35.4 2.9e-17 63.0 15.7 2.9 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF3784 PF12650.7 KII89981.1 - 0.03 14.5 0.0 0.03 14.5 0.0 3.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3784) YWFCY PF14293.6 KII89981.1 - 0.14 12.4 0.1 0.48 10.8 0.1 1.9 1 0 0 1 1 1 0 YWFCY protein PRK PF00485.18 KII89982.1 - 4.8e-48 163.5 0.0 6.9e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KII89982.1 - 7.3e-44 149.7 0.0 4.7e-43 147.0 0.0 1.9 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_33 PF13671.6 KII89982.1 - 8e-06 26.1 0.0 2.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KII89982.1 - 0.0004 20.9 0.0 0.00077 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KII89982.1 - 0.0035 16.6 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 KII89982.1 - 0.033 14.6 0.3 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 KII89982.1 - 0.048 13.3 0.1 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.12 KII89982.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CTU2 PF10288.9 KII89983.1 - 1.3e-19 70.5 0.0 3.6e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DUF2616 PF11077.8 KII89983.1 - 0.06 13.1 0.5 0.14 11.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-P11 PF03854.14 KII89983.1 - 0.6 9.8 5.4 1.6 8.4 0.1 3.2 3 0 0 3 3 3 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 KII89983.1 - 5.3 7.0 12.5 0.62 10.0 2.9 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) p450 PF00067.22 KII89984.1 - 1.2e-44 152.9 0.0 1.4e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_5 PF17121.5 KII89984.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YqjK PF13997.6 KII89984.1 - 0.25 11.6 0.1 0.25 11.6 0.1 3.2 3 0 0 3 3 3 0 YqjK-like protein Sugar_tr PF00083.24 KII89985.1 - 5e-118 394.8 23.3 6.1e-118 394.5 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII89985.1 - 1.6e-29 102.9 48.7 3.3e-19 69.0 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.20 KII89986.1 - 4.9e-64 216.7 0.0 6.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KII89986.1 - 0.23 10.5 0.0 0.43 9.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.20 KII89987.1 - 6.5e-63 213.1 0.0 8.3e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KII89987.1 - 0.011 14.9 0.0 0.041 13.0 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) UvrD-helicase PF00580.21 KII89988.1 - 6.7e-65 219.7 0.0 1.1e-64 218.9 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KII89988.1 - 5.6e-51 174.0 0.0 6.5e-50 170.5 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KII89988.1 - 1.9e-31 109.4 0.0 4e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KII89988.1 - 6.7e-13 48.3 0.1 1.8e-12 46.8 0.1 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KII89988.1 - 1e-06 28.6 0.9 0.25 11.0 0.0 3.8 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KII89988.1 - 1.4e-05 24.9 0.0 0.0084 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KII89988.1 - 0.00035 20.4 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain HSP20 PF00011.21 KII89990.1 - 8.7e-08 32.2 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII89990.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA DUF2457 PF10446.9 KII89990.1 - 0.055 12.6 11.5 0.099 11.8 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2630 PF10944.8 KII89990.1 - 0.065 13.7 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Bud13 PF09736.9 KII89991.1 - 1.9e-55 187.2 13.1 1.9e-55 187.2 13.1 2.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex FlaA PF04620.12 KII89992.1 - 0.0027 17.4 0.1 19 4.8 0.0 3.2 3 0 0 3 3 3 3 Flagellar filament outer layer protein Flaa SpoIIIAC PF06686.11 KII89992.1 - 0.018 15.2 4.7 24 5.2 0.1 3.6 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family RNase_HII PF01351.18 KII89993.1 - 1.8e-45 155.2 0.0 1.4e-37 129.5 0.0 2.0 2 0 0 2 2 2 2 Ribonuclease HII DUF3382 PF11862.8 KII89994.1 - 0.024 14.9 0.4 0.024 14.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) Chs7 PF12271.8 KII89994.1 - 0.042 13.2 0.4 0.075 12.4 0.4 1.4 1 0 0 1 1 1 0 Chitin synthase export chaperone Anoctamin PF04547.12 KII89994.1 - 0.061 12.2 0.3 0.085 11.7 0.3 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Phasin_2 PF09361.10 KII89994.1 - 0.19 12.0 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Phasin protein Trp_oprn_chp PF09534.10 KII89994.1 - 2.9 7.7 4.9 2.4 7.9 2.0 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TctB PF07331.11 KII89994.1 - 4.4 7.6 14.7 9.3 6.5 14.5 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Vac14_Fig4_bd PF11916.8 KII89995.1 - 0.03 14.0 3.4 0.068 12.8 0.1 2.3 2 1 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding CopD PF05425.13 KII89995.1 - 4 7.9 9.8 0.58 10.6 2.4 2.5 2 0 0 2 2 2 0 Copper resistance protein D DUF92 PF01940.16 KII89996.1 - 1.4e-72 244.0 9.9 1.6e-72 243.7 9.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 2H-phosphodiest PF08975.10 KII89997.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) GlyL_C PF12524.8 KII90003.1 - 3.5 7.8 8.7 0.37 10.9 1.0 2.7 2 1 0 2 2 2 0 dsDNA virus glycoprotein L C terminal TBCC_N PF16752.5 KII90007.1 - 0.018 15.5 0.6 1.1 9.7 0.0 3.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain EF-hand_5 PF13202.6 KII90007.1 - 0.03 13.8 0.0 0.08 12.5 0.0 1.8 1 0 0 1 1 1 0 EF hand PSY3 PF16836.5 KII90007.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description DUF948 PF06103.11 KII90007.1 - 0.32 11.3 4.3 4.9 7.5 0.1 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PfkB PF00294.24 KII90008.1 - 3.1e-14 53.0 0.0 1.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 3 pfkB family carbohydrate kinase MSA-2c PF12238.8 KII90008.1 - 7 6.6 6.8 17 5.4 6.8 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c TPR_19 PF14559.6 KII90009.1 - 9.2e-13 48.5 12.2 2.4e-06 28.0 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII90009.1 - 5.3e-12 46.2 5.6 9.2e-08 32.6 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII90009.1 - 1.3e-08 34.3 6.3 0.35 11.1 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII90009.1 - 1.3e-08 34.2 1.7 1.5 8.8 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII90009.1 - 1.5e-06 28.5 16.2 0.16 12.9 0.2 6.5 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII90009.1 - 2.9e-05 24.1 0.1 0.22 12.0 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII90009.1 - 5.3e-05 23.1 0.5 3 8.3 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII90009.1 - 8.4e-05 22.8 10.1 0.33 11.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII90009.1 - 0.00025 21.5 8.5 5.4 7.9 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII90009.1 - 0.00063 19.6 0.2 4.5 7.5 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII90009.1 - 0.00093 19.4 2.4 1.3 9.3 0.1 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KII90009.1 - 0.0018 18.3 0.9 0.058 13.5 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KII90009.1 - 0.0037 17.4 9.6 0.06 13.5 1.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KII90009.1 - 0.016 15.7 0.4 0.15 12.5 0.1 2.4 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation MIT PF04212.18 KII90009.1 - 0.021 14.9 0.1 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KII90009.1 - 0.024 14.5 3.1 2.4 8.1 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KII90009.1 - 0.028 13.8 2.4 1.7 7.9 0.3 2.4 2 0 0 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 KII90009.1 - 0.094 13.4 1.6 0.37 11.6 0.1 3.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Svf1 PF08622.10 KII90011.1 - 3.4e-46 157.3 0.0 4.7e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 KII90011.1 - 1.6e-43 148.4 0.0 2.3e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Peptidase_M48 PF01435.18 KII90012.1 - 9.2e-08 32.1 0.0 1.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Phage_holin_2_1 PF04971.12 KII90014.1 - 1.6 8.8 7.1 1 9.4 0.3 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S Talin_middle PF09141.10 KII90015.1 - 0.0034 17.4 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Talin, middle domain DUF3046 PF11248.8 KII90015.1 - 0.056 13.8 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) EF-hand_6 PF13405.6 KII90017.1 - 0.0033 17.2 0.1 0.056 13.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain ABC_tran_CTD PF16326.5 KII90017.1 - 0.0034 17.6 0.2 4.9 7.5 0.0 3.2 2 0 0 2 2 2 2 ABC transporter C-terminal domain EF-hand_5 PF13202.6 KII90017.1 - 0.046 13.2 0.1 0.13 11.8 0.1 1.9 1 0 0 1 1 1 0 EF hand DUF4403 PF14356.6 KII90017.1 - 0.083 11.5 0.3 0.13 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) HrpF PF06266.12 KII90017.1 - 0.1 12.9 0.5 0.58 10.5 0.4 2.3 3 0 0 3 3 3 0 HrpF protein PIN_8 PF18476.1 KII90017.1 - 0.12 12.2 0.5 0.32 10.8 0.5 1.7 1 0 0 1 1 1 0 PIN like domain EzrA PF06160.12 KII90017.1 - 0.31 9.2 4.1 0.087 11.0 0.7 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA EF-hand_1 PF00036.32 KII90017.1 - 0.35 10.5 1.4 0.67 9.6 0.0 2.3 3 0 0 3 3 3 0 EF hand Syntaxin_2 PF14523.6 KII90017.1 - 0.58 10.6 5.5 10 6.5 0.1 3.3 3 1 1 4 4 4 0 Syntaxin-like protein DUF155 PF02582.14 KII90019.1 - 7.6e-47 159.7 0.0 9.4e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SART-1 PF03343.13 KII90021.1 - 4.2e-170 567.4 68.9 3.8e-169 564.2 65.4 2.0 2 0 0 2 2 2 2 SART-1 family ADH_N_2 PF16884.5 KII90023.1 - 1.2e-28 99.1 0.0 2.2e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KII90023.1 - 2.2e-20 72.9 0.1 3.5e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII90023.1 - 6e-10 40.3 0.0 1.2e-09 39.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.16 KII90023.1 - 0.037 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein adh_short PF00106.25 KII90023.1 - 0.043 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase SpoVAE PF14097.6 KII90023.1 - 0.06 13.0 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Epimerase PF01370.21 KII90023.1 - 0.071 12.6 0.1 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 KII90023.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MIP PF00230.20 KII90024.1 - 3.1e-26 92.5 11.1 4.9e-26 91.8 11.1 1.3 1 0 0 1 1 1 1 Major intrinsic protein LsmAD PF06741.13 KII90025.1 - 5.2e-29 100.6 0.4 5.2e-29 100.6 0.4 2.0 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 KII90025.1 - 0.00025 21.1 0.1 0.00059 19.9 0.1 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Mad3_BUB1_I PF08311.12 KII90027.1 - 1.9e-40 137.7 1.0 3.7e-40 136.8 1.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KII90027.1 - 4.1e-09 36.2 0.0 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KII90027.1 - 1.4e-05 25.1 0.0 6.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 KII90027.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KII90027.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Kdo PF06293.14 KII90027.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM131 PF15010.6 KII90027.1 - 9 6.1 7.3 0.67 9.8 2.3 1.7 2 0 0 2 2 2 0 Putative cell signalling CNH PF00780.22 KII90029.1 - 1.1e-33 117.0 0.0 1.7e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KII90029.1 - 1.6e-32 113.2 0.2 2.6e-32 112.5 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KII90029.1 - 5.2e-06 26.6 0.0 2.5e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KII90029.1 - 0.031 14.8 0.0 0.095 13.2 0.0 1.9 1 1 0 1 1 1 0 PH domain PH_16 PF17838.1 KII90029.1 - 0.14 12.0 0.1 9.8 6.0 0.0 2.5 2 0 0 2 2 2 0 PH domain DUF4141 PF13605.6 KII90029.1 - 8.6 5.7 8.0 0.23 10.7 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) Lactonase PF10282.9 KII90030.1 - 6.3e-08 32.2 0.0 1.2e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller PASTA PF03793.19 KII90030.1 - 0.0084 15.9 0.0 0.14 12.0 0.1 2.9 3 0 0 3 3 3 1 PASTA domain Big_2 PF02368.18 KII90030.1 - 0.073 13.0 2.7 0.28 11.1 2.2 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) WD40 PF00400.32 KII90031.1 - 1e-30 105.3 9.8 8.4e-07 29.6 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90031.1 - 2.6e-13 50.1 0.0 1e-05 25.7 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII90031.1 - 4.2e-06 26.0 0.0 0.0062 15.5 0.0 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KII90031.1 - 4.5e-05 23.2 1.9 0.00067 19.3 1.3 2.8 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 KII90031.1 - 0.0087 15.4 0.0 9.3 5.5 0.0 3.2 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KII90031.1 - 0.25 9.9 0.1 13 4.3 0.0 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Helicase_C PF00271.31 KII90032.1 - 3.1e-14 53.3 0.0 6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90032.1 - 6.5e-11 42.3 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase TxDE PF18711.1 KII90032.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme EF-1_beta_acid PF10587.9 KII90035.1 - 3.4 8.2 6.9 8.8 6.9 6.9 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region zf-CCHC PF00098.23 KII90038.1 - 0.16 12.1 2.6 0.31 11.2 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KII90038.1 - 0.98 9.3 4.5 1.8 8.5 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 KII90038.1 - 2.7 7.8 6.3 5.5 6.8 6.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF659 PF04937.15 KII90039.1 - 3.5e-15 56.2 0.6 7.4e-15 55.1 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 KII90039.1 - 2.9e-06 27.0 1.6 4.5e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region CUE PF02845.16 KII90040.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain DEC-1_N PF04625.13 KII90040.1 - 0.23 10.5 13.9 0.27 10.2 13.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Transposase_21 PF02992.14 KII90042.1 - 7.3e-05 22.1 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KII90042.1 - 0.0023 17.5 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plavaka PF18759.1 KII90042.1 - 0.047 12.9 0.1 0.082 12.1 0.1 1.3 1 0 0 1 1 1 0 Plavaka transposase UBN_AB PF14075.6 KII90042.1 - 0.15 11.8 2.4 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain HypA PF01155.19 KII90042.1 - 0.22 11.6 0.8 25 4.9 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KII90042.1 - 0.3 11.3 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zinc_ribbon_2 PF13240.6 KII90042.1 - 8 6.3 9.4 11 5.9 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KII90042.1 - 9.1 6.4 10.5 2.4 8.2 0.5 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain AA_permease_2 PF13520.6 KII90043.1 - 1.1e-56 192.5 41.9 1.3e-56 192.3 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.32 KII90045.1 - 7.7e-93 301.9 60.5 3e-10 40.5 0.4 12.7 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90045.1 - 3e-30 104.4 9.4 0.00036 20.8 0.0 9.9 3 1 7 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII90045.1 - 3.3e-23 82.2 19.5 0.004 16.2 0.0 10.5 2 1 9 11 11 11 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KII90045.1 - 1.7e-14 53.1 0.3 0.012 14.0 0.0 7.0 3 2 4 7 7 7 4 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KII90045.1 - 1.4e-12 47.2 17.2 8.4 6.5 0.0 10.9 11 0 0 11 11 11 2 WD40-like Beta Propeller Repeat NACHT PF05729.12 KII90045.1 - 4.9e-11 42.8 0.0 8.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KII90045.1 - 1.1e-06 28.2 7.3 0.42 9.9 0.1 5.7 4 2 2 7 7 7 4 WD40-like domain AAA_16 PF13191.6 KII90045.1 - 5.6e-06 26.8 0.0 1.9e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain eIF2A PF08662.11 KII90045.1 - 5.9e-06 26.3 2.5 0.096 12.6 0.0 4.6 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A AAA PF00004.29 KII90045.1 - 0.0003 21.2 0.0 0.0013 19.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII90045.1 - 0.0011 19.2 0.0 0.0045 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.16 KII90045.1 - 0.0028 16.2 1.2 0.92 8.0 0.0 3.9 3 2 1 4 4 4 1 Cytochrome D1 heme domain NTPase_1 PF03266.15 KII90045.1 - 0.009 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.22 KII90045.1 - 0.05 12.8 0.3 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Rx_N PF18052.1 KII90045.1 - 0.052 13.8 0.4 0.19 12.0 0.4 1.9 1 0 0 1 1 1 0 Rx N-terminal domain NFRKB_winged PF14465.6 KII90045.1 - 0.071 13.3 0.1 19 5.5 0.0 3.8 4 0 0 4 4 4 0 NFRKB Winged Helix-like APS_kinase PF01583.20 KII90045.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KII90045.1 - 0.26 11.8 1.0 1.5 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain Gp_dh_C PF02800.20 KII90052.1 - 8.4e-69 230.2 0.0 1.1e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KII90052.1 - 1.1e-37 128.4 0.2 2.2e-37 127.5 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII90052.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 KII90052.1 - 0.089 12.9 1.2 0.31 11.2 0.2 2.3 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 KII90053.1 - 1.9e-25 89.6 26.5 4e-16 58.9 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KII90053.1 - 0.0027 16.1 6.1 0.0056 15.0 0.8 3.1 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family YhhN PF07947.14 KII90054.1 - 0.0047 16.6 0.3 0.0058 16.3 0.3 1.1 1 0 0 1 1 1 1 YhhN family DUF872 PF05915.12 KII90054.1 - 0.12 12.5 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Ldh_1_N PF00056.23 KII90055.1 - 1.1e-46 158.4 0.1 3.3e-46 156.9 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KII90055.1 - 1.9e-42 145.0 0.0 2.6e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KII90055.1 - 0.00077 18.5 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KII90055.1 - 0.44 9.8 5.1 0.95 8.8 0.1 3.2 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Latrophilin PF02354.16 KII90057.1 - 0.032 13.3 0.3 0.055 12.5 0.3 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region NUDE_C PF04880.13 KII90057.1 - 0.056 13.9 0.9 3.1 8.3 0.0 3.1 3 0 0 3 3 3 0 NUDE protein, C-terminal conserved region DUF4218 PF13960.6 KII90058.1 - 4.5e-06 26.2 0.1 9.9e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Plavaka PF18759.1 KII90059.1 - 0.00024 20.4 0.1 0.00029 20.2 0.1 1.1 1 0 0 1 1 1 1 Plavaka transposase Abhydrolase_9_N PF15420.6 KII90062.1 - 0.068 13.2 5.8 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Fes1 PF08609.10 KII90063.1 - 7.1e-25 87.7 0.1 2.4e-24 86.0 0.1 2.0 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 SIL1 PF16782.5 KII90063.1 - 4.9e-05 22.7 0.0 6.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 KII90063.1 - 0.022 15.1 0.0 0.26 11.7 0.0 2.3 1 1 0 1 1 1 0 HEAT repeats V-ATPase_H_N PF03224.14 KII90063.1 - 0.025 13.9 0.1 0.14 11.4 0.1 1.9 2 1 1 3 3 3 0 V-ATPase subunit H HEAT PF02985.22 KII90063.1 - 0.058 13.7 0.0 8 7.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 KII90063.1 - 0.087 13.4 0.1 19 5.9 0.0 3.0 2 1 0 2 2 2 0 HEAT-like repeat Glyco_hydro_115 PF15979.5 KII90065.1 - 2.9e-119 398.5 0.1 4.7e-119 397.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KII90065.1 - 5.3e-55 185.9 0.0 1.1e-54 184.9 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain RsgA_GTPase PF03193.16 KII90065.1 - 0.18 11.7 0.2 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Troponin-I_N PF11636.8 KII90066.1 - 0.89 9.6 5.0 1.8 8.6 5.0 1.5 1 0 0 1 1 1 0 Troponin I residues 1-32 ANAPC4_WD40 PF12894.7 KII90067.1 - 8.7e-11 42.0 0.2 0.00027 21.2 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII90067.1 - 1e-07 32.5 19.5 4.2e-05 24.2 0.5 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KII90067.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DUF202 PF02656.15 KII90068.1 - 0.0033 17.8 2.0 0.0033 17.8 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Hist_rich_Ca-bd PF10529.9 KII90068.1 - 0.58 10.5 4.2 1.1 9.5 4.2 1.5 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region DEAD PF00270.29 KII90069.1 - 8.5e-14 51.7 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII90069.1 - 2.5e-08 34.2 0.0 6.9e-07 29.6 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain EF1_GNE PF00736.19 KII90072.1 - 4.5e-33 113.3 1.9 4.5e-33 113.3 1.9 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KII90072.1 - 2.7e-13 50.1 9.6 2.7e-13 50.1 9.6 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 KII90072.1 - 0.00036 20.7 0.5 0.013 15.7 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII90072.1 - 0.0021 18.2 0.2 0.009 16.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII90072.1 - 0.032 14.2 0.1 0.42 10.7 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OapA_N PF08525.11 KII90075.1 - 2.3 8.2 0.0 2.3 8.2 0.0 2.6 3 0 0 3 3 3 0 Opacity-associated protein A N-terminal motif F-box-like PF12937.7 KII90077.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like VIGSSK PF14773.6 KII90080.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal ANAPC4_WD40 PF12894.7 KII90082.1 - 2.9e-10 40.3 0.5 0.00026 21.2 0.0 3.4 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII90082.1 - 8.3e-09 35.9 8.7 2.5e-05 25.0 1.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.25 KII90084.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain HLH PF00010.26 KII90086.1 - 1.8e-14 53.4 0.1 2.8e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M16 PF00675.20 KII90087.1 - 2.6e-21 76.2 0.1 4.9e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) GATA PF00320.27 KII90088.1 - 2.3e-25 87.9 19.5 3.8e-15 55.2 3.3 2.6 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 KII90088.1 - 5.9e-11 42.0 1.0 1.2e-10 41.0 1.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 KII90088.1 - 0.024 14.7 5.4 1.9 8.6 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 KII90088.1 - 0.037 14.2 5.4 0.71 10.1 0.9 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 KII90088.1 - 0.12 12.3 5.6 4.2 7.3 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KII90088.1 - 0.42 10.2 7.2 0.48 10.0 0.8 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KII90088.1 - 0.73 10.1 2.6 0.99 9.7 0.8 2.1 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_4 PF13717.6 KII90088.1 - 0.99 9.4 4.4 2.2 8.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KII90088.1 - 1.9 8.0 6.0 3.7 7.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KII90088.1 - 3.3 7.7 9.3 2.2 8.2 2.1 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Cytochrom_c3_2 PF14537.6 KII90088.1 - 3.6 8.1 8.7 6.6 7.3 1.1 2.7 1 1 2 3 3 3 0 Cytochrome c3 DZR PF12773.7 KII90088.1 - 4.1 7.5 10.4 31 4.7 0.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Elf1 PF05129.13 KII90088.1 - 8.8 6.4 6.5 5 7.2 0.2 2.7 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Glyco_hydro_1 PF00232.18 KII90091.1 - 5.4e-111 371.2 0.2 7e-111 370.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_1 PF00232.18 KII90092.1 - 2.6e-108 362.4 0.2 3.5e-108 362.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 NST1 PF13945.6 KII90093.1 - 2.2e-55 187.7 0.0 2.2e-55 187.7 0.0 4.7 4 2 1 5 5 5 1 Salt tolerance down-regulator PhoLip_ATPase_C PF16212.5 KII90096.1 - 4.1e-52 177.4 23.8 4.1e-52 177.4 23.8 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KII90096.1 - 2.9e-17 62.1 4.3 6.8e-17 60.9 4.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KII90096.1 - 3.1e-16 60.3 1.2 9.7e-11 42.3 0.6 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KII90096.1 - 1.5e-14 53.9 0.0 1.5e-14 53.9 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KII90096.1 - 2.1e-08 34.1 0.0 4.3e-07 29.9 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KII90096.1 - 0.00035 20.4 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 KII90098.1 - 8.7e-11 41.7 0.0 6.8e-10 38.7 0.0 2.3 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90098.1 - 2.1e-06 27.2 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII90098.1 - 0.004 16.5 0.1 0.0065 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.26 KII90099.1 - 2e-26 92.5 0.8 3e-26 91.9 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII90099.1 - 3.7e-19 70.1 0.1 8.5e-19 68.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90099.1 - 3e-07 30.3 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.6 KII90099.1 - 0.011 15.8 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 SIS domain AlaDh_PNT_C PF01262.21 KII90099.1 - 0.033 13.5 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 KII90099.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DHHC PF01529.20 KII90100.1 - 9.9e-32 109.9 5.4 9.9e-32 109.9 5.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Sdh_cyt PF01127.22 KII90100.1 - 0.22 11.6 3.0 0.55 10.3 2.5 1.8 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PocR PF10114.9 KII90100.1 - 0.43 10.4 2.4 0.77 9.5 2.4 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR ABA_GPCR PF12430.8 KII90101.1 - 4.6e-45 153.6 4.7 4.6e-45 153.6 4.7 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KII90101.1 - 8.7e-16 57.8 0.0 2.6e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal TRC8_N PF13705.6 KII90101.1 - 6.8 5.5 14.3 1.2 7.9 6.5 2.1 2 0 0 2 2 2 0 TRC8 N-terminal domain EF1G PF00647.19 KII90102.1 - 1.2e-44 150.7 0.2 1.9e-44 150.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KII90102.1 - 3.9e-12 46.3 0.0 1.1e-11 44.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII90102.1 - 6.2e-11 42.4 0.0 1.7e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII90102.1 - 4e-09 36.7 0.0 1.7e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII90102.1 - 3.7e-07 30.1 0.0 1.2e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII90102.1 - 1.4e-06 28.4 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 KII90102.1 - 0.0071 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII90102.1 - 0.016 15.5 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KII90102.1 - 0.046 13.5 0.0 0.23 11.3 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.19 KII90102.1 - 6.2 7.5 12.1 13 6.4 12.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein NAD_binding_10 PF13460.6 KII90103.1 - 1.6e-30 106.4 0.1 1.9e-30 106.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KII90103.1 - 0.006 16.7 0.4 0.88 9.7 0.0 2.4 2 1 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.9 KII90105.1 - 8.5e-09 35.8 0.7 2.5e-08 34.3 0.7 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KII90105.1 - 6.1e-06 26.5 0.3 8.7e-06 26.0 0.3 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport BP28CT PF08146.12 KII90106.1 - 1.9e-31 109.1 0.5 6.5e-31 107.3 0.5 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KII90106.1 - 1.9e-12 47.6 0.6 1.9e-12 47.6 0.6 4.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 DRIM PF07539.12 KII90106.1 - 0.016 13.5 1.1 2.7 6.2 0.0 3.6 4 0 0 4 4 4 0 Down-regulated in metastasis HEAT PF02985.22 KII90106.1 - 0.11 12.8 0.1 0.11 12.8 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 KII90107.1 - 2.3e-34 119.0 0.0 3.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90107.1 - 9.7e-27 93.9 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII90107.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 KII90107.1 - 3.1e-05 24.2 0.0 7.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PBD PF00786.28 KII90109.1 - 9.2e-06 25.9 0.3 0.082 13.3 0.0 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain Ribonuclease_T2 PF00445.18 KII90110.1 - 8.6e-37 127.1 0.1 1.2e-36 126.6 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family HARP PF07443.13 KII90110.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) Tudor-knot PF11717.8 KII90111.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain BAG PF02179.16 KII90112.1 - 4.3e-07 30.3 0.0 6.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 BAG domain IQ PF00612.27 KII90112.1 - 0.0093 15.7 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3645 PF12359.8 KII90112.1 - 0.068 12.6 0.8 0.14 11.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) ADH_zinc_N PF00107.26 KII90113.1 - 2.5e-28 98.7 1.2 3.9e-28 98.0 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII90113.1 - 3.9e-18 66.8 0.2 8.1e-18 65.8 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90113.1 - 1.1e-10 41.4 0.0 7.7e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KII90113.1 - 0.0077 15.6 0.8 0.011 15.0 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 KII90113.1 - 0.014 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3285 PF11688.8 KII90114.1 - 2.4 8.1 5.8 9.6 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3285) HSP70 PF00012.20 KII90116.1 - 1.1e-83 281.4 2.2 1.1e-83 281.4 2.2 1.9 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KII90116.1 - 3.4e-06 26.1 0.2 8.8e-06 24.8 0.2 1.7 1 1 0 1 1 1 1 MreB/Mbl protein DUF3829 PF12889.7 KII90116.1 - 0.11 12.0 5.7 0.058 12.9 3.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF5563 PF17718.1 KII90116.1 - 0.17 11.4 2.4 0.48 9.9 2.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Membr_traf_MHD PF10540.9 KII90117.1 - 2.3e-24 86.3 0.0 2.8e-21 76.2 0.0 2.9 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KII90117.1 - 1.2e-10 41.6 0.0 3.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 KII90117.1 - 0.00074 18.2 1.4 0.0067 15.0 0.0 2.2 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) LRR_4 PF12799.7 KII90118.1 - 0.00071 19.9 0.5 0.83 10.2 0.0 3.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII90118.1 - 0.0026 17.5 1.6 0.043 13.6 0.2 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KII90118.1 - 0.05 14.2 0.7 6.7 7.7 0.2 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat SRI PF08236.11 KII90119.1 - 2.8e-18 65.9 13.7 1e-17 64.0 13.7 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KII90119.1 - 5.3e-17 62.7 0.4 5.3e-17 62.7 0.4 3.5 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KII90119.1 - 8e-14 51.4 9.3 8e-14 51.4 9.3 2.0 2 0 0 2 2 2 1 AWS domain SIR4_SID PF16991.5 KII90119.1 - 1.1 9.2 8.4 2.7 8.0 8.4 1.6 1 0 0 1 1 1 0 Sir4 SID domain R_equi_Vir PF05526.11 KII90119.1 - 2.5 7.9 4.1 4.6 7.1 4.1 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RNA_pol_I_A49 PF06870.12 KII90120.1 - 2.5e-106 355.8 0.4 2.9e-106 355.6 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3530 PF12048.8 KII90120.1 - 0.0066 15.9 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) F-box-like PF12937.7 KII90123.1 - 0.00061 19.6 8.6 0.013 15.3 8.6 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII90123.1 - 0.067 13.1 3.2 13 5.8 0.3 3.3 3 0 0 3 3 3 0 F-box domain zf-primase PF09329.11 KII90124.1 - 2.4e-16 59.3 2.3 4.3e-16 58.4 2.3 1.5 1 0 0 1 1 1 1 Primase zinc finger Coilin_N PF15862.5 KII90124.1 - 8.7 6.1 6.5 26 4.6 6.5 1.8 1 0 0 1 1 1 0 Coilin N-terminus DUF1365 PF07103.11 KII90126.1 - 3.1e-64 216.9 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MFS_1 PF07690.16 KII90127.1 - 3.4e-36 124.9 32.1 3.4e-36 124.9 32.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 KII90128.1 - 5.5e-17 62.6 0.0 1.1e-16 61.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII90128.1 - 3.7e-11 43.4 0.0 6.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR PF05347.15 KII90129.1 - 1.5e-10 40.9 0.4 3e-10 40.0 0.4 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KII90129.1 - 0.00011 22.9 0.3 0.00013 22.6 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.9 KII90130.1 - 3.8e-24 84.9 12.3 3.8e-24 84.9 12.3 2.6 2 1 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 V-SNARE PF05008.15 KII90132.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus eIF2_C PF09173.11 KII90133.1 - 2e-34 117.7 0.7 4.9e-34 116.4 0.7 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KII90133.1 - 3.3e-21 75.7 1.5 5.1e-20 71.8 1.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KII90133.1 - 1.6e-11 44.4 1.6 2.5e-11 43.8 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KII90133.1 - 0.0038 17.1 0.4 0.046 13.6 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KII90133.1 - 0.018 15.1 1.7 0.027 14.5 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KII90133.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPR_2 PF13041.6 KII90134.1 - 2.5e-09 37.2 0.0 0.0064 16.7 0.0 3.8 3 0 0 3 3 3 2 PPR repeat family PPR_long PF17177.4 KII90134.1 - 0.00069 19.0 0.1 0.36 10.1 0.1 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KII90134.1 - 0.00084 19.4 0.2 0.23 11.6 0.0 4.2 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.20 KII90134.1 - 0.04 14.2 0.0 0.51 10.7 0.0 2.8 2 0 0 2 2 2 0 PPR repeat RRM_1 PF00076.22 KII90135.1 - 4.5e-06 26.4 0.0 6.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RINGv PF12906.7 KII90136.1 - 1.4e-06 28.3 6.8 3.1e-06 27.2 6.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KII90136.1 - 0.0039 17.5 6.9 0.0039 17.5 6.9 1.6 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KII90136.1 - 0.0075 16.4 3.2 0.013 15.6 3.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KII90136.1 - 0.019 14.6 3.0 0.18 11.4 1.5 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD_4 PF16866.5 KII90136.1 - 0.023 14.8 5.8 0.045 13.8 5.8 1.4 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.6 KII90136.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ADH_zinc_N PF00107.26 KII90137.1 - 1.2e-09 38.3 0.1 2e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90137.1 - 2.8e-09 36.8 0.4 2.7e-08 33.7 0.4 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII90137.1 - 0.001 20.1 0.0 0.0017 19.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Helicase_RecD PF05127.14 KII90137.1 - 0.093 12.6 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Helicase F-box-like PF12937.7 KII90138.1 - 1.1e-07 31.6 2.8 1.1e-07 31.6 2.8 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KII90138.1 - 2.7 8.0 7.5 0.71 9.8 0.5 3.0 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.16 KII90139.1 - 1.2e-34 119.8 39.5 1.6e-34 119.4 39.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KII90139.1 - 0.0059 16.9 9.8 0.029 14.7 1.6 4.2 3 1 0 3 3 3 2 Phage holin family Hol44, in holin superfamily V Phage_holin_2_4 PF16082.5 KII90139.1 - 0.056 13.2 1.9 0.1 12.4 0.4 2.3 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 KII90140.1 - 6.3e-35 120.7 37.4 9.8e-35 120.1 37.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.20 KII90140.1 - 0.00011 22.1 1.9 0.00011 22.1 1.9 3.4 3 1 0 3 3 3 1 Inhibitor of apoptosis-promoting Bax1 DUF2238 PF09997.9 KII90140.1 - 0.0088 15.8 2.1 0.011 15.5 0.4 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2238) Phage_holin_2_4 PF16082.5 KII90140.1 - 0.13 12.0 0.1 0.49 10.1 0.1 2.1 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Phage_holin_5_2 PF16079.5 KII90140.1 - 0.46 10.8 12.3 0.081 13.3 1.2 4.3 2 2 2 4 4 4 0 Phage holin family Hol44, in holin superfamily V Bap31 PF05529.12 KII90141.1 - 3.6e-42 143.4 5.2 6e-42 142.7 5.2 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KII90141.1 - 4.7e-10 39.3 5.7 4.7e-10 39.3 5.7 2.1 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_P85_iSH2 PF16454.5 KII90141.1 - 0.021 14.4 2.3 0.021 14.4 2.3 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Lipoprotein_6 PF01441.19 KII90141.1 - 0.024 14.7 2.2 0.036 14.1 2.2 1.3 1 0 0 1 1 1 0 Lipoprotein Zip PF02535.22 KII90141.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.10 KII90141.1 - 0.18 11.8 5.8 0.11 12.6 1.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal UCH PF00443.29 KII90142.1 - 1.9e-39 135.7 0.0 2.8e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII90142.1 - 1.1e-09 38.3 0.5 5e-07 29.6 0.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KII90142.1 - 2.9e-05 23.7 0.0 7.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family RasGEF PF00617.19 KII90143.1 - 3.6e-28 99.0 0.0 6.6e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII90143.1 - 2.6e-09 37.3 0.1 5.3e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SET PF00856.28 KII90144.1 - 1.9e-12 47.9 0.0 4.6e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 SET domain Herpes_gp2 PF05955.11 KII90144.1 - 0.13 11.8 4.2 0.2 11.1 2.7 1.8 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 Lactonase PF10282.9 KII90145.1 - 2.6e-35 122.3 0.0 3.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KII90145.1 - 7.1e-05 22.5 0.0 0.00019 21.1 0.0 1.7 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KII90145.1 - 0.0044 17.2 0.0 0.032 14.4 0.0 2.5 1 0 0 1 1 1 1 Arylesterase PD40 PF07676.12 KII90145.1 - 0.022 14.7 1.6 35 4.5 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF4322 PF14210.6 KII90145.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) PQQ_3 PF13570.6 KII90145.1 - 2.3 8.8 6.4 12 6.5 2.6 3.6 3 1 0 3 3 3 0 PQQ-like domain ASF1_hist_chap PF04729.13 KII90146.1 - 3e-65 218.9 0.0 3.4e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone p450 PF00067.22 KII90147.1 - 7.5e-59 199.7 0.0 1.7e-58 198.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 UCH PF00443.29 KII90148.1 - 1.1e-07 31.6 0.0 8.9e-07 28.7 0.0 2.0 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 KII90148.1 - 0.00034 20.4 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 KII90148.1 - 0.0008 19.2 3.2 0.061 13.3 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KII90148.1 - 0.018 15.7 0.1 0.13 12.9 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Syntaxin-6_N PF09177.11 KII90148.1 - 0.13 12.8 0.9 0.4 11.3 0.1 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 KII90148.1 - 0.15 12.6 0.7 0.28 11.7 0.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Osmo_CC PF08946.10 KII90148.1 - 0.81 10.0 7.0 0.75 10.1 0.6 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Fra10Ac1 PF09725.9 KII90149.1 - 2.1e-45 153.8 0.0 3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 60KD_IMP PF02096.20 KII90151.1 - 1.6e-12 47.6 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Na_H_Exchanger PF00999.21 KII90152.1 - 3.8e-71 239.9 35.9 4.9e-71 239.5 35.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 KII90152.1 - 0.0039 17.6 0.0 1.2 9.5 0.0 3.0 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_60s PF00428.19 KII90152.1 - 0.072 13.7 4.2 1.2 9.8 0.0 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein G-alpha PF00503.20 KII90153.1 - 1.8e-113 379.4 0.0 2.1e-113 379.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII90153.1 - 1e-11 44.6 0.1 1.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KII90153.1 - 0.0018 18.5 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KII90153.1 - 0.0047 16.2 0.1 0.027 13.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 KII90153.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 KII90153.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain VirB8 PF04335.13 KII90155.1 - 0.27 11.0 3.4 0.39 10.5 3.4 1.2 1 0 0 1 1 1 0 VirB8 protein DUF2583 PF10762.9 KII90158.1 - 3.5 8.1 8.1 0.47 10.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) PIN_4 PF13638.6 KII90159.1 - 1.7e-12 47.8 0.3 2.4e-08 34.3 0.1 2.5 1 1 1 2 2 2 2 PIN domain EST1_DNA_bind PF10373.9 KII90159.1 - 1.7e-09 37.6 0.0 4.9e-08 32.8 0.0 2.7 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Alpha_kinase PF02816.18 KII90161.1 - 1.6e-06 28.3 1.2 1.3e-05 25.5 1.2 1.9 1 1 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 KII90162.1 - 1.4e-20 74.2 0.0 2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family p450 PF00067.22 KII90165.1 - 4.2e-62 210.4 0.0 4.2e-60 203.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KII90166.1 - 8.5e-35 120.2 0.0 1.5e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KII90166.1 - 2.5e-29 102.2 0.0 3.9e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KII90166.1 - 2.2e-08 33.9 0.0 6.2e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KII90166.1 - 0.00018 21.8 0.0 0.001 19.3 0.0 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KII90166.1 - 0.0048 16.8 0.0 0.041 13.8 0.0 2.5 2 1 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 KII90166.1 - 0.077 12.9 0.0 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 KR domain Bromo_TP PF07524.13 KII90167.1 - 4.2e-09 36.3 0.7 4e-08 33.1 0.2 2.1 1 1 1 2 2 2 1 Bromodomain associated CENP-T_C PF15511.6 KII90167.1 - 0.016 15.3 0.0 5 7.3 0.0 2.3 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KII90167.1 - 0.073 13.5 0.0 2.1 8.8 0.0 2.2 1 1 1 2 2 2 0 CENP-S protein SRAP PF02586.14 KII90168.1 - 1.6e-70 237.0 0.0 5.1e-70 235.4 0.0 1.7 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) SWIRM-assoc_2 PF16496.5 KII90168.1 - 0.081 11.8 2.9 0.12 11.3 2.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DSPc PF00782.20 KII90170.1 - 3.4e-26 91.6 0.0 5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 KII90170.1 - 6.6e-06 26.6 0.0 2.7e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 KII90170.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KII90170.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CUE PF02845.16 KII90171.1 - 3.1e-08 33.2 0.0 4.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain NmrA PF05368.13 KII90172.1 - 1.9e-42 145.4 0.1 1e-41 143.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KII90172.1 - 2.4e-15 56.9 1.6 3.1e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KII90172.1 - 4e-10 39.5 0.2 2.6e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII90172.1 - 1.9e-08 34.2 3.2 3e-08 33.5 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KII90172.1 - 2.6e-08 33.6 1.0 6.2e-05 22.6 0.2 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII90172.1 - 0.00025 20.1 0.1 0.0004 19.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 KII90172.1 - 0.0043 16.4 0.0 0.047 13.0 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KII90172.1 - 0.0057 15.8 0.2 3 6.9 0.1 3.1 3 1 0 3 3 3 2 RmlD substrate binding domain Semialdhyde_dh PF01118.24 KII90172.1 - 0.038 14.4 0.3 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KII90172.1 - 0.084 13.6 0.2 0.17 12.6 0.2 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.13 KII90173.1 - 4.8e-42 144.1 0.0 5.6e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII90173.1 - 1.9e-14 54.0 0.1 2.5e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII90173.1 - 4.4e-07 29.6 0.3 6.8e-07 29.0 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII90173.1 - 1.9e-05 23.8 0.2 2.6e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KII90173.1 - 0.0047 17.2 0.3 0.008 16.4 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KII90173.1 - 0.031 14.7 0.1 0.057 13.9 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KII90173.1 - 0.033 14.9 0.2 0.055 14.2 0.2 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.10 KII90173.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KII90174.1 - 1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII90174.1 - 8.5e-08 31.9 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase CsbD PF05532.12 KII90175.1 - 0.0076 16.1 4.4 0.014 15.3 4.4 1.5 1 0 0 1 1 1 1 CsbD-like GATase_4 PF13230.6 KII90176.1 - 9.1e-09 34.6 0.0 6.9e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KII90176.1 - 2.7e-07 30.9 0.0 5.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Rtt106 PF08512.12 KII90177.1 - 6.3e-19 68.2 0.0 1.8e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KII90177.1 - 0.003 17.5 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain LANC_like PF05147.13 KII90178.1 - 8.1e-29 100.3 0.0 3.1e-28 98.4 0.0 1.8 1 1 1 2 2 2 1 Lanthionine synthetase C-like protein DUF4419 PF14388.6 KII90179.1 - 1.1e-93 313.9 0.1 1.3e-93 313.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) UPF0565 PF10561.9 KII90179.1 - 0.03 13.5 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF4419 PF14388.6 KII90180.1 - 0.016 14.6 0.0 0.018 14.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) WD40 PF00400.32 KII90181.1 - 4.8e-05 24.1 0.2 0.14 13.0 0.2 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat UIM PF02809.20 KII90181.1 - 0.01 15.7 0.8 0.041 13.8 0.8 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif P16-Arc PF04699.14 KII90182.1 - 2.5e-51 174.0 0.0 3e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2711 PF10924.8 KII90182.1 - 0.029 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Utp12 PF04003.12 KII90182.1 - 0.094 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF4454 PF14628.6 KII90182.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) DUF4470 PF14737.6 KII90183.1 - 2.1e-09 37.5 0.0 4.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_1 PF00515.28 KII90183.1 - 7.7e-05 22.3 0.1 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII90183.1 - 0.00069 19.5 0.7 0.024 14.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII90183.1 - 0.0021 17.7 0.9 0.0076 15.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TubC_N PF18563.1 KII90183.1 - 0.024 14.6 0.2 0.066 13.2 0.2 1.8 1 0 0 1 1 1 0 TubC N-terminal docking domain TPR_14 PF13428.6 KII90183.1 - 0.092 13.6 0.5 5.9 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 KII90185.1 - 1.5e-25 90.2 0.0 3.3e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase HU-HIG PF18291.1 KII90185.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif SWIB PF02201.18 KII90186.1 - 3e-22 78.3 0.0 7.8e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain BAR PF03114.18 KII90187.1 - 3.8e-38 131.5 14.9 5.4e-38 131.0 14.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KII90187.1 - 6.4e-14 51.3 0.4 1.8e-13 49.9 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KII90187.1 - 1.9e-11 43.7 0.2 3.4e-11 42.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KII90187.1 - 1.3e-09 37.6 0.0 2.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KII90187.1 - 2.2e-07 30.8 7.7 4.6e-07 29.8 7.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Filament PF00038.21 KII90187.1 - 0.0013 18.4 13.4 0.0026 17.4 13.4 1.4 1 0 0 1 1 1 1 Intermediate filament protein LicD PF04991.13 KII90187.1 - 0.0025 18.0 1.3 0.0045 17.2 1.3 1.5 1 0 0 1 1 1 1 LicD family FAM92 PF06730.11 KII90187.1 - 0.035 13.5 7.4 0.014 14.8 4.7 1.7 2 0 0 2 2 2 0 FAM92 protein FIVAR PF07554.13 KII90187.1 - 0.045 14.5 0.5 0.16 12.7 0.5 1.9 1 0 0 1 1 1 0 FIVAR domain TPR_MLP1_2 PF07926.12 KII90187.1 - 0.082 13.0 16.7 0.13 12.3 15.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KII90187.1 - 0.17 10.7 13.0 0.32 9.8 13.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 KII90187.1 - 0.73 9.6 9.0 1.6 8.5 9.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fib_alpha PF08702.10 KII90187.1 - 1.2 9.3 8.1 2.6 8.2 8.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KII90187.1 - 2.1 8.4 12.3 5 7.2 12.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 KII90187.1 - 2.8 6.7 3.2 3.9 6.3 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF883 PF05957.13 KII90187.1 - 2.9 8.6 6.3 2.2 8.9 3.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SNase PF00565.17 KII90188.1 - 1.5e-19 70.5 0.0 2.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue FAD_binding_1 PF00667.20 KII90191.1 - 4.6e-36 124.5 0.0 6.4e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KII90191.1 - 1.5e-26 93.3 0.0 2.4e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KII90191.1 - 1.3e-09 38.6 0.0 2.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_3_C PF01915.22 KII90196.1 - 3e-52 177.5 0.0 4.7e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII90196.1 - 6.4e-38 130.9 0.0 1.1e-37 130.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII90196.1 - 9.4e-17 60.9 0.0 1.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Plavaka PF18759.1 KII90199.1 - 1.4e-131 438.5 0.0 2e-131 438.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 KII90199.1 - 0.16 12.9 0.2 0.16 12.9 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KII90199.1 - 3.7 8.2 6.6 0.63 10.6 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type LRR_8 PF13855.6 KII90201.1 - 1.1 9.1 2.6 18 5.2 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat RRM_1 PF00076.22 KII90202.1 - 2.7e-27 94.4 0.2 3e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KII90202.1 - 0.056 13.7 0.0 2.9 8.1 0.0 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KII90202.1 - 0.081 13.1 0.0 0.75 9.9 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif GRP PF07172.11 KII90202.1 - 1.1 10.0 36.9 2.2 9.0 36.9 1.6 1 0 0 1 1 1 0 Glycine rich protein family ABC1 PF03109.16 KII90203.1 - 2.3e-26 92.3 0.0 4e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 KII90203.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain YihI PF04220.12 KII90204.1 - 0.012 15.3 1.4 0.019 14.7 1.4 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) PEMT PF04191.13 KII90205.1 - 4.7e-32 110.5 3.6 8.1e-32 109.8 2.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase LRR_8 PF13855.6 KII90206.1 - 0.094 12.5 0.2 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat UQ_con PF00179.26 KII90207.1 - 5.2e-33 113.6 0.0 7e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.24 KII90209.1 - 2.9e-103 346.1 18.8 3.4e-103 345.9 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90209.1 - 6.5e-26 91.1 28.1 6.1e-18 64.9 1.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KII90209.1 - 2e-05 23.1 1.1 2e-05 23.1 1.1 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family OTU PF02338.19 KII90210.1 - 2e-13 51.0 0.0 3.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KII90210.1 - 0.056 12.9 0.0 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain F-box-like PF12937.7 KII90211.1 - 0.12 12.2 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 F-box-like adh_short PF00106.25 KII90212.1 - 1.7e-44 151.6 0.0 2.1e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII90212.1 - 5.7e-32 111.1 0.0 7.6e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90212.1 - 2e-09 37.6 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII90212.1 - 1.5e-08 34.4 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KII90212.1 - 0.00076 19.4 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII90212.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SNF2_N PF00176.23 KII90213.1 - 1.9e-51 174.8 0.0 3.6e-51 173.9 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII90213.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII90213.1 - 9.5e-07 29.0 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KII90213.1 - 7.9e-05 22.4 1.6 0.00015 21.5 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII90213.1 - 0.00013 21.7 2.4 0.00026 20.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII90213.1 - 0.0002 21.2 0.9 0.00037 20.4 0.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII90213.1 - 0.0005 20.0 0.9 0.00099 19.1 0.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII90213.1 - 0.00078 19.7 2.2 0.0017 18.6 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KII90213.1 - 0.0023 18.0 2.7 0.0045 17.1 2.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SWI2_SNF2 PF18766.1 KII90213.1 - 0.005 16.5 0.0 0.0083 15.8 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4_3 PF13920.6 KII90213.1 - 0.0053 16.6 1.4 0.0095 15.8 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KII90213.1 - 0.046 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 KII90213.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Prok-RING_4 PF14447.6 KII90213.1 - 4.3 7.3 6.7 75 3.3 0.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF2141 PF09912.9 KII90214.1 - 0.081 12.9 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) Ras PF00071.22 KII90216.1 - 2.6e-35 121.4 0.0 3.3e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII90216.1 - 1.5e-10 41.3 0.0 3.8e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KII90216.1 - 1.4e-07 31.2 0.1 6.6e-06 25.7 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KII90216.1 - 1.4e-05 25.2 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII90216.1 - 0.00098 18.7 0.0 0.16 11.5 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII90216.1 - 0.007 16.3 0.0 3.1 7.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 KII90216.1 - 0.0087 15.5 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KII90216.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KII90216.1 - 0.088 12.2 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 KII90216.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_rhamnosid6H PF17389.2 KII90218.1 - 3.9e-17 62.5 0.0 5.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KII90218.1 - 3.4e-08 33.1 0.0 6.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KII90218.1 - 0.064 12.2 0.2 0.13 11.2 0.2 1.5 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KII90218.1 - 0.085 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Trehalase F-box-like PF12937.7 KII90221.1 - 5.5e-08 32.6 0.1 2e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 F-box-like Macro PF01661.21 KII90222.1 - 1.4e-39 134.8 0.1 1.9e-39 134.3 0.1 1.2 1 0 0 1 1 1 1 Macro domain PigN PF04987.14 KII90223.1 - 2.3e-131 438.8 38.1 2.8e-131 438.5 38.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KII90223.1 - 2.3e-08 34.1 1.5 3.7e-06 26.8 1.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KII90223.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KII90223.1 - 0.018 14.4 0.1 0.036 13.5 0.0 1.4 2 0 0 2 2 2 0 Sulfatase Peroxidase_2 PF01328.17 KII90224.1 - 3.4e-43 148.4 0.0 4.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF1687 PF07955.11 KII90225.1 - 5.1e-22 78.7 0.0 9.3e-22 77.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1687) Amino_oxidase PF01593.24 KII90226.1 - 3.5e-43 148.6 0.0 4.6e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII90226.1 - 2e-09 37.6 0.0 6.1e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII90226.1 - 0.00041 19.7 0.0 0.00066 19.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII90226.1 - 0.00053 19.3 0.7 0.00053 19.3 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII90226.1 - 0.014 14.1 0.3 0.024 13.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein DUF3824 PF12868.7 KII90227.1 - 0.00019 22.1 2.0 0.00037 21.2 2.0 1.5 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Herpes_gE PF02480.16 KII90227.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EAP30 PF04157.16 KII90228.1 - 5.8e-36 124.0 0.0 7.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KII90228.1 - 8.1e-19 67.6 0.0 1.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.7 KII90228.1 - 0.0039 17.2 4.9 0.42 10.7 1.3 2.4 2 0 0 2 2 2 2 Double zinc ribbon zf-RanBP PF00641.18 KII90228.1 - 0.0042 16.4 12.4 0.14 11.5 1.5 2.7 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KII90228.1 - 0.0052 16.2 0.8 0.0052 16.2 0.8 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KII90228.1 - 0.095 12.8 5.1 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Sporozoite_P67 PF05642.11 KII90228.1 - 2.1 6.3 5.2 3 5.8 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mito_carr PF00153.27 KII90229.1 - 1.1e-53 179.2 1.0 2e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.12 KII90229.1 - 1.9 9.0 5.3 1.3 9.6 0.1 3.2 4 0 0 4 4 4 0 The GLUG motif SRP9-21 PF05486.12 KII90230.1 - 6.9e-11 42.4 1.2 2.6e-09 37.4 1.2 2.3 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 KII90230.1 - 0.05 13.6 0.1 0.07 13.1 0.1 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DEAD PF00270.29 KII90231.1 - 4.5e-10 39.6 0.0 7.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII90231.1 - 8.3e-06 26.1 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mucin PF01456.17 KII90233.1 - 0.01 15.8 11.3 0.01 15.8 11.3 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Pilin_N PF07790.11 KII90233.1 - 0.019 15.9 0.6 0.043 14.7 0.6 1.7 1 1 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF4834 PF16118.5 KII90233.1 - 0.27 12.2 0.0 0.45 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) STE PF02200.16 KII90235.1 - 7.6e-36 122.9 0.0 1.3e-35 122.1 0.0 1.4 1 1 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KII90236.1 - 1.5e-14 53.5 10.8 2.1e-07 31.0 1.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII90236.1 - 4.3e-11 42.7 9.3 1.4e-05 25.5 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII90236.1 - 1.3e-07 31.8 14.6 1.1e-06 28.8 4.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KII90236.1 - 1.7e-06 28.1 0.3 0.018 15.3 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KII90236.1 - 0.00014 21.8 8.3 0.00016 21.5 0.1 2.6 2 1 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KII90236.1 - 0.00022 21.5 1.3 0.1 13.1 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 KII90236.1 - 0.0021 18.4 6.1 0.082 13.4 0.3 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 KII90236.1 - 0.0026 18.0 2.2 0.0043 17.3 2.2 1.4 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 KII90236.1 - 0.003 17.5 5.3 0.09 12.8 0.1 2.1 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 KII90236.1 - 0.0039 17.5 0.7 0.29 11.5 0.1 2.0 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KII90236.1 - 0.013 15.0 2.1 0.014 14.9 0.1 2.0 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 KII90236.1 - 0.03 14.1 13.0 0.28 11.0 1.5 2.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain GAGA PF09237.11 KII90236.1 - 0.042 13.7 4.9 0.66 9.8 1.0 2.1 1 1 1 2 2 2 0 GAGA factor FOXP-CC PF16159.5 KII90236.1 - 0.069 13.8 2.0 4.2 8.1 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KII90236.1 - 0.12 12.3 5.4 3.1 7.8 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_C2H2_ZHX PF18387.1 KII90236.1 - 0.14 11.8 1.8 8.2 6.2 0.0 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Elf1 PF05129.13 KII90236.1 - 1.1 9.4 4.1 0.25 11.4 0.9 1.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-C2H2_12 PF18112.1 KII90236.1 - 1.1 9.8 5.2 1.3 9.6 0.2 2.7 2 2 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Phosphorylase PF00343.20 KII90237.1 - 4.9e-298 990.4 0.0 5.7e-298 990.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.11 KII90238.1 - 6.7e-16 58.5 0.0 1.7e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 KII90238.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 RhoGAP domain zf_C2H2_13 PF18508.1 KII90239.1 - 0.099 12.2 0.2 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger domain Sugar_tr PF00083.24 KII90241.1 - 7.2e-82 275.6 17.7 8.7e-82 275.4 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90241.1 - 1.4e-17 63.7 33.6 1e-09 37.8 9.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily NAD_binding_4 PF07993.12 KII90242.1 - 1.4e-34 119.4 0.0 2.2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII90242.1 - 2.9e-28 98.6 0.0 8.1e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KII90242.1 - 8.2e-09 35.3 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII90242.1 - 0.00024 21.1 0.0 0.001 19.0 0.0 2.1 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KII90242.1 - 0.00028 20.8 0.0 0.002 18.0 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII90242.1 - 0.0043 16.1 0.0 0.011 14.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 KII90242.1 - 0.016 15.5 0.4 0.31 11.4 0.2 2.7 2 1 0 2 2 2 0 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KII90242.1 - 0.041 13.3 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KII90242.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KII90242.1 - 0.078 12.1 0.0 0.16 11.1 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 KII90244.1 - 3e-07 30.1 0.0 1.3e-06 28.0 0.0 2.0 1 1 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 KII90244.1 - 0.0059 15.4 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KII90244.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Statherin PF03875.13 KII90244.1 - 0.14 12.3 3.9 1 9.5 0.2 2.9 3 0 0 3 3 3 0 Statherin MFS_1 PF07690.16 KII90245.1 - 2.4e-22 79.3 64.6 3.2e-19 69.1 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KII90246.1 - 4.5e-88 295.7 0.1 6.1e-88 295.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII90246.1 - 0.11 13.4 0.0 0.47 11.5 0.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF948 PF06103.11 KII90247.1 - 0.0049 17.1 0.2 29 5.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PhoU PF01895.19 KII90247.1 - 0.03 14.8 0.6 0.068 13.6 0.5 1.7 1 1 0 1 1 1 0 PhoU domain STN1_2 PF09170.10 KII90247.1 - 0.039 14.2 0.2 0.092 13.0 0.2 1.6 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GARP PF16731.5 KII90247.1 - 0.1 12.3 1.7 3.6 7.2 0.2 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma CHIP_TPR_N PF18391.1 KII90247.1 - 0.19 12.5 6.8 0.61 10.9 6.8 1.9 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain DUF2570 PF10828.8 KII90247.1 - 0.41 10.5 2.1 6.2 6.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TBCA PF02970.16 KII90247.1 - 0.67 10.3 8.2 1.1 9.7 3.4 2.7 1 1 2 3 3 3 0 Tubulin binding cofactor A GldM_N PF12081.8 KII90247.1 - 0.94 9.5 4.9 12 6.0 0.3 2.2 1 1 0 2 2 2 0 GldM N-terminal domain Transformer PF06495.11 KII90248.1 - 0.03 14.4 9.2 0.035 14.2 9.2 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein LEA_6 PF10714.9 KII90249.1 - 1.5 9.0 6.6 0.16 12.0 0.4 2.4 2 1 1 3 3 3 0 Late embryogenesis abundant protein 18 FAS_N PF17828.1 KII90250.1 - 0.00012 22.1 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta Macoilin PF09726.9 KII90252.1 - 3.5 6.1 7.0 3.5 6.1 7.0 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KII90252.1 - 9.7 5.3 13.1 13 4.8 13.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuc_red_2_N PF08471.10 KII90253.1 - 0.0027 17.8 0.0 0.71 10.1 0.0 3.7 1 1 3 4 4 4 2 Class II vitamin B12-dependent ribonucleotide reductase Lipase_GDSL_2 PF13472.6 KII90254.1 - 8.4e-15 55.6 4.8 2e-14 54.4 4.8 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII90254.1 - 2.4e-06 27.7 0.1 5e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KII90254.1 - 0.023 14.8 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 KII90254.1 - 0.042 13.8 0.0 0.15 12.1 0.0 1.9 1 1 1 2 2 2 0 Carbohydrate esterase 2 N-terminal Peptidase_A21 PF03566.13 KII90255.1 - 0.32 9.2 1.3 0.35 9.1 1.3 1.0 1 0 0 1 1 1 0 Peptidase family A21 MFS_1 PF07690.16 KII90256.1 - 6.6e-23 81.2 51.6 2.9e-14 52.8 31.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII90256.1 - 1.7e-18 66.7 22.6 3.3e-17 62.5 22.6 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter B12D PF06522.11 KII90257.1 - 7.3 6.5 6.0 2.4 8.0 3.2 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Prefoldin PF02996.17 KII90258.1 - 3.3e-25 88.3 0.1 4e-24 84.8 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit BCAS3 PF12490.8 KII90258.1 - 0.058 12.9 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Syntaxin-6_N PF09177.11 KII90258.1 - 0.15 12.6 2.2 2.1 8.9 0.3 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal XhlA PF10779.9 KII90258.1 - 0.67 10.2 2.5 20 5.5 0.1 2.8 3 0 0 3 3 3 0 Haemolysin XhlA RRM_1 PF00076.22 KII90259.1 - 3.5e-72 238.2 0.0 3.8e-17 61.9 0.0 6.2 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII90259.1 - 5.6e-08 32.5 0.0 0.0031 17.3 0.0 4.9 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KII90259.1 - 8.8e-05 22.5 0.3 1 9.5 0.0 4.4 3 1 1 4 4 4 1 RNA binding motif PHM7_cyt PF14703.6 KII90259.1 - 0.00033 20.9 4.3 28 4.9 0.0 6.5 6 2 2 8 8 8 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KII90259.1 - 0.00082 19.4 0.1 1.7 8.8 0.0 4.4 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.6 KII90259.1 - 0.018 15.1 0.7 50 4.0 0.0 4.1 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KII90259.1 - 0.049 13.4 0.1 49 3.7 0.0 4.4 4 1 1 5 5 5 0 Rrp7 RRM-like N-terminal domain GMC_oxred_N PF00732.19 KII90260.1 - 1.8e-52 178.6 0.0 2.8e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII90260.1 - 5.9e-31 107.9 0.0 1.1e-30 107.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII90260.1 - 0.01 15.0 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Ank_2 PF12796.7 KII90262.1 - 0.0016 18.9 0.0 0.0034 17.9 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KII90262.1 - 0.01 16.1 0.9 6.5 7.2 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Velvet PF11754.8 KII90263.1 - 7.5e-53 180.0 0.8 7.5e-53 180.0 0.8 3.3 2 2 0 2 2 2 1 Velvet factor Patatin PF01734.22 KII90267.1 - 9.7e-20 71.6 0.0 1.9e-19 70.6 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase CARM1 PF11531.8 KII90267.1 - 0.028 14.6 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal TPR_10 PF13374.6 KII90268.1 - 3.4e-147 475.0 26.1 1.5e-12 47.0 0.0 17.0 17 0 0 17 17 17 15 Tetratricopeptide repeat TPR_12 PF13424.6 KII90268.1 - 5.6e-111 363.0 52.9 4.5e-14 52.5 0.5 14.0 3 2 12 15 15 15 15 Tetratricopeptide repeat TPR_7 PF13176.6 KII90268.1 - 2.8e-41 136.5 23.6 0.032 14.3 0.3 14.9 16 0 0 16 16 16 13 Tetratricopeptide repeat TPR_MalT PF17874.1 KII90268.1 - 7.3e-32 111.1 83.8 9.9e-09 35.0 7.4 5.8 1 1 8 9 9 9 7 MalT-like TPR region TPR_1 PF00515.28 KII90268.1 - 1.2e-31 107.2 37.1 0.053 13.4 0.0 15.6 16 0 0 16 16 16 12 Tetratricopeptide repeat TPR_4 PF07721.14 KII90268.1 - 3.7e-30 101.4 1.2 0.068 13.8 0.1 14.3 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_19 PF14559.6 KII90268.1 - 1.7e-28 98.9 25.5 0.19 12.3 0.1 14.4 7 3 7 15 15 15 8 Tetratricopeptide repeat TPR_17 PF13431.6 KII90268.1 - 1.1e-27 94.3 28.9 0.11 12.9 0.1 14.5 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 KII90268.1 - 1.3e-22 78.1 33.8 0.88 9.8 0.1 15.1 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 KII90268.1 - 2.2e-20 71.1 38.6 0.079 13.2 0.2 15.1 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 KII90268.1 - 2.7e-20 72.7 1.1 2.2 9.0 0.0 12.0 10 1 2 12 12 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII90268.1 - 1.9e-05 25.1 22.8 34 5.6 0.0 11.7 13 0 0 13 13 12 0 Tetratricopeptide repeat TPR_20 PF14561.6 KII90268.1 - 0.00076 19.8 19.7 20 5.6 0.0 9.3 4 2 6 11 11 11 0 Tetratricopeptide repeat RHS_repeat PF05593.14 KII90268.1 - 0.0039 17.7 1.0 40 4.9 0.0 5.4 5 0 0 5 5 4 0 RHS Repeat ECSCR PF15820.5 KII90268.1 - 0.006 16.4 0.4 2.9 7.8 0.0 5.1 6 2 1 7 7 4 1 Endothelial cell-specific chemotaxis regulator ANAPC3 PF12895.7 KII90268.1 - 0.0083 16.3 12.9 14 6.0 0.0 7.9 5 4 2 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 GST_C_4 PF14834.6 KII90268.1 - 0.054 13.9 0.2 1.2 9.5 0.1 2.9 2 1 1 3 3 2 0 Glutathione S-transferase, C-terminal domain PPR PF01535.20 KII90268.1 - 0.063 13.6 17.3 59 4.2 0.0 10.3 15 0 0 15 15 11 0 PPR repeat DUF3157 PF11355.8 KII90268.1 - 0.065 12.9 3.7 47 3.5 0.0 5.2 5 2 2 7 7 7 0 Protein of unknown function (DUF3157) DUF3660 PF12398.8 KII90268.1 - 0.59 10.2 3.1 94 3.2 0.1 5.3 8 0 0 8 8 8 0 Receptor serine/threonine kinase PTSIIA_gutA PF03829.13 KII90268.1 - 0.88 9.5 6.1 25 4.8 0.0 4.3 5 1 2 7 7 7 0 PTS system glucitol/sorbitol-specific IIA component TPR_3 PF07720.12 KII90268.1 - 1.5 8.9 25.0 1.3 9.1 0.0 9.2 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF1897 PF09005.10 KII90268.1 - 2.8 7.5 16.8 9 5.9 0.0 7.5 12 0 0 12 12 10 0 Domain of unknown function (DUF1897) Cyt_bd_oxida_II PF02322.15 KII90270.1 - 0.0013 18.2 1.7 0.0018 17.7 0.8 1.6 1 1 1 2 2 2 1 Cytochrome bd terminal oxidase subunit II DUF2185 PF09951.9 KII90271.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DAHP_synth_1 PF00793.20 KII90273.1 - 1.6e-84 283.1 0.0 2e-66 223.7 0.0 2.5 2 1 0 2 2 2 2 DAHP synthetase I family Patatin PF01734.22 KII90274.1 - 2.3e-20 73.6 0.0 3.6e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 KII90275.1 - 2e-25 90.2 0.0 3.1e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase PIH1 PF08190.12 KII90276.1 - 1e-18 67.3 0.0 1.6e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 PIH1 N-terminal domain LIM PF00412.22 KII90277.1 - 4e-26 91.0 19.2 2.6e-14 53.2 4.5 2.2 2 0 0 2 2 2 2 LIM domain zf-ACC PF17848.1 KII90277.1 - 0.024 14.7 6.2 9.7 6.4 0.1 3.5 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 KII90277.1 - 0.08 12.5 11.2 8.4 6.1 0.3 4.5 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF4428 PF14471.6 KII90277.1 - 0.12 12.3 1.2 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DUF1720 PF08226.11 KII90277.1 - 0.14 12.6 13.5 1.6 9.2 3.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1720) DUF678 PF05077.12 KII90277.1 - 1.8 8.7 5.5 3.6 7.8 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF678) NinD PF17466.2 KII90277.1 - 6.1 7.0 8.2 0.97 9.6 0.4 3.2 3 1 0 3 3 3 0 Family of unknown function eIF-5a PF01287.20 KII90278.1 - 7.6e-29 99.6 0.7 1.1e-28 99.1 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KII90278.1 - 0.0025 17.8 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Lipase_3 PF01764.25 KII90280.1 - 1.3e-32 112.6 0.0 1.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KII90280.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-RanBP PF00641.18 KII90281.1 - 0.00068 18.9 14.9 0.0046 16.3 2.2 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_12 PF13087.6 KII90282.1 - 1.2e-55 188.2 0.0 1.7e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII90282.1 - 7.7e-48 163.5 0.0 1e-47 163.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII90282.1 - 8.7e-15 55.3 0.1 2e-14 54.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII90282.1 - 4.7e-10 39.5 0.4 1.2e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KII90282.1 - 1.1e-05 25.1 0.1 2.2e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KII90282.1 - 0.00015 21.6 0.1 5.3 6.7 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KII90282.1 - 0.042 14.3 0.1 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KII90282.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 KII90282.1 - 0.22 10.7 1.1 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Macoilin PF09726.9 KII90282.1 - 0.59 8.6 1.0 0.85 8.1 1.0 1.1 1 0 0 1 1 1 0 Macoilin family RVT_1 PF00078.27 KII90283.1 - 2.2e-07 30.6 0.0 4.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KII90283.1 - 0.03 15.0 0.0 0.076 13.7 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase SAP PF02037.27 KII90285.1 - 0.064 13.0 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 SAP domain Rft-1 PF04506.13 KII90286.1 - 2.2e-124 416.1 0.6 2.6e-124 415.8 0.6 1.0 1 0 0 1 1 1 1 Rft protein Syja_N PF02383.18 KII90287.1 - 7.7e-78 262.0 0.2 1.2e-77 261.4 0.2 1.3 1 0 0 1 1 1 1 SacI homology domain DUF5308 PF17233.2 KII90288.1 - 0.0032 17.7 1.5 0.022 15.0 2.0 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF5308) SR-25 PF10500.9 KII90292.1 - 0.0013 18.4 16.9 0.0029 17.3 16.9 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 KII90292.1 - 0.049 11.9 22.7 0.059 11.7 20.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Dsh_C PF12316.8 KII90292.1 - 0.098 13.1 3.8 0.17 12.3 3.8 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal YL1 PF05764.13 KII90292.1 - 0.2 11.7 25.7 0.03 14.4 21.8 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Dehydrin PF00257.19 KII90292.1 - 0.32 11.5 12.9 0.59 10.7 12.9 1.4 1 0 0 1 1 1 0 Dehydrin DNA_pol_phi PF04931.13 KII90292.1 - 1.3 7.0 26.6 1.2 7.1 23.0 2.0 2 0 0 2 2 2 0 DNA polymerase phi RR_TM4-6 PF06459.12 KII90292.1 - 2 8.2 12.4 3.3 7.4 12.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 KII90292.1 - 2.6 8.5 9.7 5.2 7.5 9.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Atrophin-1 PF03154.15 KII90292.1 - 3.5 5.8 11.1 4.8 5.3 11.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFIIE-A_C PF11521.8 KII90292.1 - 5.1 7.5 13.9 2.6 8.4 10.5 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF1943 PF09172.11 KII90292.1 - 8 5.6 9.2 13 4.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Sec62 PF03839.16 KII90292.1 - 8.4 5.8 10.1 18 4.7 10.1 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Asp_protease PF09668.10 KII90293.1 - 0.069 12.9 0.0 0.18 11.6 0.0 1.6 1 1 0 2 2 2 0 Aspartyl protease DDE_3 PF13358.6 KII90298.1 - 0.041 13.7 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease KDZ PF18758.1 KII90299.1 - 2e-64 217.3 0.0 3.4e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII90299.1 - 2.5e-08 34.0 0.1 6.3e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII90299.1 - 5.8e-07 29.6 0.1 1.1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases PT PF04886.12 KII90301.1 - 5.8e-07 28.9 12.5 5.8e-07 28.9 12.5 4.0 3 1 0 3 3 3 1 PT repeat GPP34 PF05719.11 KII90303.1 - 0.42 10.6 8.6 1.3 9.0 7.6 1.9 1 1 1 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Retrotran_gag_2 PF14223.6 KII90306.1 - 6e-17 61.6 0.0 8.1e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII90306.1 - 0.009 16.1 5.5 0.014 15.5 5.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 KII90306.1 - 0.74 9.7 3.8 1.3 9.0 3.8 1.3 1 0 0 1 1 1 0 Zinc knuckle TMEM40 PF15817.5 KII90307.1 - 0.81 9.5 2.1 7.1 6.4 0.2 2.1 1 1 1 2 2 2 0 Transmembrane protein 40 family Tmemb_9 PF05434.11 KII90307.1 - 6.2 6.7 10.3 2.2 8.2 4.0 2.0 1 1 1 2 2 2 0 TMEM9 Retrotran_gag_2 PF14223.6 KII90308.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KII90308.1 - 0.012 15.6 5.9 0.027 14.6 5.9 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KII90308.1 - 0.38 10.6 5.3 0.94 9.4 5.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.19 KII90309.1 - 1.8e-11 44.0 0.0 2.7e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DpnII-MboI PF18742.1 KII90309.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 REase_DpnII-MboI eIF3_subunit PF08597.10 KII90312.1 - 3.7 7.4 13.5 3.9 7.3 13.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tet_JBP PF12851.7 KII90315.1 - 0.00012 21.5 0.0 0.00076 18.9 0.0 1.8 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Retrotran_gag_2 PF14223.6 KII90316.1 - 2.7e-14 53.0 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NIBRIN_BRCT_II PF16508.5 KII90317.1 - 0.028 14.7 0.0 0.082 13.2 0.0 1.8 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein DUF3402 PF11882.8 KII90317.1 - 0.11 11.6 1.0 0.24 10.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) FHA PF00498.26 KII90317.1 - 0.13 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 FHA domain RTT107_BRCT_5 PF16770.5 KII90317.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain CAP59_mtransfer PF11735.8 KII90318.1 - 1.5e-34 119.8 0.0 2.7e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 OTCace_N PF02729.21 KII90319.1 - 1.3e-44 151.8 0.0 1.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KII90319.1 - 2.9e-43 147.7 0.0 3.8e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_C37 PF05416.12 KII90319.1 - 0.075 11.5 0.1 0.1 11.1 0.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glycogen_syn PF05693.13 KII90320.1 - 0 1094.7 0.0 0 1094.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 KII90320.1 - 8e-07 29.0 0.4 3.2e-06 27.0 0.3 2.0 3 0 0 3 3 3 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 KII90320.1 - 1.1e-06 29.1 0.0 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KII90320.1 - 1.9e-06 27.5 0.0 0.00029 20.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KII90320.1 - 1e-05 26.1 0.8 5.6e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KII90320.1 - 1.7e-05 24.9 1.9 3.9e-05 23.7 1.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Ribonuc_L-PSP PF01042.21 KII90321.1 - 1.3e-32 112.4 0.0 1.4e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribonuc_L-PSP PF01042.21 KII90322.1 - 1.1e-34 119.0 0.0 1.3e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AAA_27 PF13514.6 KII90322.1 - 0.17 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ribonuc_L-PSP PF01042.21 KII90323.1 - 9.5e-32 109.6 0.0 1e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP JmjC PF02373.22 KII90324.1 - 9.9e-39 132.3 0.1 2.1e-38 131.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 KII90324.1 - 4.9e-16 58.4 0.6 1.5e-15 56.8 0.6 1.9 2 0 0 2 2 2 1 jmjN domain zf-HC5HC2H PF13771.6 KII90324.1 - 3.6e-12 46.4 1.4 3.6e-12 46.4 1.4 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KII90324.1 - 7.7e-11 42.1 3.2 1.2e-10 41.5 1.1 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 KII90324.1 - 0.002 18.0 5.5 0.0072 16.2 5.5 2.0 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 KII90324.1 - 0.75 10.0 4.1 1.6 9.0 4.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain YL1 PF05764.13 KII90326.1 - 0.073 13.2 5.9 0.15 12.2 5.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Helicase_C PF00271.31 KII90327.1 - 1.4e-15 57.6 0.0 4e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90327.1 - 2.2e-13 50.4 0.0 5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII90327.1 - 7.7e-06 26.0 0.0 2.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KII90327.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Plavaka PF18759.1 KII90328.1 - 8.2e-39 133.7 0.0 1.1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-MYND PF01753.18 KII90329.1 - 1.2e-07 31.7 14.2 1.2e-07 31.7 14.2 1.8 2 0 0 2 2 2 1 MYND finger Mating_N PF12731.7 KII90329.1 - 0.11 12.6 0.1 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein beta 1 zf-C6H2 PF15801.5 KII90329.1 - 0.45 10.9 11.6 1.4 9.3 11.6 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Zn_Tnp_IS91 PF14319.6 KII90329.1 - 0.56 10.3 8.9 1.6 8.8 8.9 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain GST_N PF02798.20 KII90330.1 - 1.3e-11 44.7 0.0 5.1e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KII90330.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII90330.1 - 1.3e-05 25.4 0.0 2.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KII90330.1 - 0.0033 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII90330.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2844 PF11005.8 KII90331.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2844) DDDD PF10161.9 KII90331.1 - 0.24 11.2 0.9 0.75 9.6 0.9 1.9 1 0 0 1 1 1 0 Putative mitochondrial precursor protein ENTH PF01417.20 KII90332.1 - 8.7e-51 171.2 0.1 1.6e-50 170.3 0.1 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KII90332.1 - 5.9e-05 22.2 4.8 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 1 ANTH domain TraG_N PF07916.11 KII90332.1 - 0.86 8.4 7.0 1.6 7.5 7.0 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Thioredoxin_11 PF18078.1 KII90332.1 - 3.2 7.9 9.6 13 6.0 9.6 2.0 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain PI-PLC-Y PF00387.19 KII90334.1 - 0.085 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Cellulase PF00150.18 KII90335.1 - 9.5e-32 110.5 1.9 1.5e-31 109.9 1.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_1 PF00133.22 KII90336.1 - 4.2e-212 705.6 0.0 4.8e-211 702.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KII90336.1 - 2e-35 122.0 0.1 5.2e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KII90336.1 - 2.1e-14 53.1 0.0 5.2e-07 28.8 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KII90336.1 - 9.7e-10 38.3 0.1 8.8e-06 25.4 0.1 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KII90336.1 - 0.038 13.3 0.0 0.47 9.8 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF1524 PF07510.11 KII90337.1 - 4.8e-09 36.2 0.0 6.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Peptidase_C12 PF01088.21 KII90338.1 - 5.9e-52 176.5 0.0 9.1e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KII90338.1 - 3.3e-07 30.1 0.0 9.5e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases CCDC53 PF10152.9 KII90338.1 - 0.13 12.7 0.4 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Mid1 PF12929.7 KII90339.1 - 2.3e-60 205.0 0.0 2.9e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KII90339.1 - 0.013 16.1 7.4 2.2 9.0 7.4 2.6 1 1 0 1 1 1 0 Fz domain ASXH PF13919.6 KII90340.1 - 1.3e-29 103.0 0.1 2e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Asx homology domain ABC1 PF03109.16 KII90341.1 - 2e-29 102.2 0.0 3.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KII90341.1 - 0.0047 16.9 0.1 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII90341.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF21 PF01595.20 KII90342.1 - 2.6e-32 112.0 0.2 4e-32 111.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KII90342.1 - 0.017 15.6 1.4 16 6.0 0.1 3.6 3 0 0 3 3 3 0 CBS domain STE3 PF02076.15 KII90344.1 - 0.14 11.3 9.4 0.55 9.4 9.4 1.9 1 1 0 1 1 1 0 Pheromone A receptor CBF PF03914.17 KII90346.1 - 2.1e-43 148.3 0.1 6.5e-41 140.2 0.0 3.0 3 0 0 3 3 3 2 CBF/Mak21 family Cnd1 PF12717.7 KII90346.1 - 0.00023 21.2 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KII90346.1 - 0.006 15.2 0.2 0.013 14.1 0.2 1.5 1 0 0 1 1 1 1 Adaptin N terminal region DUF5096 PF17019.5 KII90346.1 - 0.077 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) RTP1_C1 PF10363.9 KII90346.1 - 0.19 11.9 0.3 0.56 10.4 0.3 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 MFS_1 PF07690.16 KII90347.1 - 8.3e-20 71.0 36.1 1.2e-19 70.4 36.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Siva PF05458.12 KII90348.1 - 0.0045 16.7 6.1 0.0045 16.7 6.1 2.3 2 1 0 2 2 2 1 Cd27 binding protein (Siva) FYVE_2 PF02318.16 KII90348.1 - 3.3 8.0 10.3 4.2 7.6 1.7 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger MFS_1 PF07690.16 KII90349.1 - 7.3e-26 90.9 44.2 5.3e-15 55.2 14.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily EthD PF07110.11 KII90350.1 - 0.00011 23.2 0.3 0.72 11.0 0.0 2.3 2 0 0 2 2 2 2 EthD domain p450 PF00067.22 KII90351.1 - 3.4e-60 204.1 0.0 1.6e-59 201.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Collagen PF01391.18 KII90352.1 - 0.0055 16.4 34.3 0.0055 16.4 34.3 6.5 4 2 2 6 6 6 2 Collagen triple helix repeat (20 copies) NRBF2 PF08961.10 KII90353.1 - 5.9e-05 22.8 0.2 5.9e-05 22.8 0.2 1.7 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator DUF2353 PF09789.9 KII90353.1 - 0.0035 16.8 1.1 0.0049 16.3 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Jnk-SapK_ap_N PF09744.9 KII90353.1 - 0.015 15.5 4.2 0.026 14.7 4.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 KII90353.1 - 0.022 14.1 0.4 0.027 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prp19 PF08606.11 KII90353.1 - 0.028 14.4 3.3 0.037 14.0 0.4 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like APG6_N PF17675.1 KII90353.1 - 0.029 14.9 4.6 0.044 14.3 4.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Takusan PF04822.13 KII90353.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Takusan PikAIV_N PF18605.1 KII90353.1 - 0.14 11.8 10.3 0.1 12.2 6.2 2.4 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HALZ PF02183.18 KII90353.1 - 0.26 11.6 2.5 0.72 10.1 2.5 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper GED PF02212.18 KII90353.1 - 0.85 9.8 6.6 8 6.7 0.3 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain ZapB PF06005.12 KII90353.1 - 1.7 9.1 7.0 0.57 10.7 2.7 2.0 1 1 1 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KII90353.1 - 4.1 7.2 5.3 1.2 9.0 2.0 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF2992 PF11208.8 KII90353.1 - 6.3 7.0 7.8 0.55 10.5 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Acetyltransf_7 PF13508.7 KII90354.1 - 7.1e-09 36.0 0.0 1.6e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII90354.1 - 1.1e-08 35.1 0.0 5.3e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII90354.1 - 1.7e-07 31.5 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII90354.1 - 0.0019 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KII90354.1 - 0.0038 17.3 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Methyltransf_16 PF10294.9 KII90355.1 - 1.8e-17 63.6 0.0 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase GidB PF02527.15 KII90355.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G KRAB PF01352.27 KII90355.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 KRAB box CMD PF02627.20 KII90356.1 - 2.7e-12 46.5 0.9 2e-10 40.6 0.5 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Atrophin-1 PF03154.15 KII90357.1 - 9 4.4 8.2 14 3.9 8.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family Zf_RING PF16744.5 KII90358.1 - 0.023 14.8 0.9 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 KIAA1045 RING finger Kdo PF06293.14 KII90361.1 - 6.6e-08 32.2 0.0 8.4e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII90361.1 - 1e-05 25.6 0.1 0.00084 19.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KII90361.1 - 0.00039 19.9 0.0 0.00046 19.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 KII90361.1 - 0.00072 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KII90361.1 - 0.0035 17.0 0.0 0.26 10.9 0.0 2.1 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KII90361.1 - 0.096 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SEP PF08059.13 KII90362.1 - 2.1e-24 85.9 0.0 7e-24 84.2 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 KII90362.1 - 9.2e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain OB_aCoA_assoc PF01796.17 KII90362.1 - 0.071 13.1 0.0 4.5 7.4 0.0 2.7 3 0 0 3 3 3 0 DUF35 OB-fold domain, acyl-CoA-associated MAGE PF01454.19 KII90363.1 - 8.2e-54 182.5 0.0 1.4e-53 181.7 0.0 1.4 1 0 0 1 1 1 1 MAGE family SLAIN PF15301.6 KII90363.1 - 0.2 10.9 1.1 0.34 10.1 1.1 1.4 1 0 0 1 1 1 0 SLAIN motif-containing family GCIP PF13324.6 KII90363.1 - 0.25 10.9 7.9 0.18 11.4 1.3 2.6 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting Nucleo_P87 PF07267.11 KII90363.1 - 1.6 7.5 3.3 2.9 6.6 3.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pox_Ag35 PF03286.14 KII90363.1 - 2.3 8.0 7.8 1.2 8.9 2.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 KII90363.1 - 5.2 7.1 9.7 13 5.8 0.3 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal PI-PLC-X PF00388.19 KII90364.1 - 7.2e-43 145.7 0.0 1.1e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KII90364.1 - 6.8e-33 113.4 0.0 1.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KII90364.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 C2 domain SPC25 PF06703.11 KII90365.1 - 0.12 12.2 2.3 0.2 11.4 2.3 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Sugar_tr PF00083.24 KII90366.1 - 4e-123 411.6 16.6 4.7e-123 411.4 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90366.1 - 1.3e-17 63.8 43.6 5.4e-12 45.3 19.3 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KII90366.1 - 2 8.7 12.7 0.042 14.1 3.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) PIN_4 PF13638.6 KII90367.1 - 1e-05 25.8 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain Abhydrolase_4 PF08386.10 KII90368.1 - 5.5e-20 71.4 0.1 7.1e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 TAP-like protein Methyltransf_32 PF13679.6 KII90369.1 - 9.7 6.1 7.0 4.3 7.3 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KII90370.1 - 8.9e-21 74.7 0.0 1.2e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MaAIMP_sms PF16951.5 KII90370.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit adh_short_C2 PF13561.6 KII90371.1 - 2e-10 40.6 0.0 3.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII90371.1 - 1.5e-08 34.4 0.0 9.1e-08 31.8 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KII90371.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 KII90371.1 - 0.063 12.7 0.1 0.18 11.2 0.0 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KII90372.1 - 5.1e-41 140.7 0.0 6.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII90372.1 - 1e-12 48.4 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII90372.1 - 6e-07 29.2 0.1 1.1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII90372.1 - 1.1e-05 24.6 0.1 1.4e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 KII90372.1 - 0.0041 17.8 0.0 0.0067 17.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KII90372.1 - 0.064 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KII90372.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ion_trans PF00520.31 KII90373.1 - 3e-120 400.0 94.7 1e-38 133.0 5.9 5.1 5 0 0 5 5 5 5 Ion transport protein PCI PF01399.27 KII90374.1 - 3.1e-07 30.8 0.5 9.8e-05 22.8 0.0 3.1 2 0 0 2 2 2 2 PCI domain DUF4467 PF14729.6 KII90374.1 - 4.6 7.7 14.3 0.028 14.8 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Sugar_tr PF00083.24 KII90375.1 - 3.1e-119 398.8 21.1 3.6e-119 398.6 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90375.1 - 5.8e-18 64.9 52.6 4.8e-13 48.8 20.0 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily PsaL PF02605.15 KII90375.1 - 0.22 11.2 2.8 0.67 9.6 0.1 2.6 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI Glyco_hydro_28 PF00295.17 KII90376.1 - 1.6e-33 116.2 7.4 2.1e-33 115.8 7.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Prefoldin PF02996.17 KII90377.1 - 2.1e-27 95.4 3.0 2.7e-27 95.1 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 KII90377.1 - 0.00034 20.6 0.9 0.00073 19.5 0.8 1.6 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 KII90377.1 - 0.00095 19.4 1.9 0.054 13.7 0.1 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 KII90377.1 - 0.0024 18.0 5.4 0.2 11.8 1.0 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family COG2 PF06148.11 KII90377.1 - 0.004 17.2 3.3 0.47 10.5 0.7 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 KII90377.1 - 0.008 16.1 5.9 0.063 13.2 0.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit Med30 PF11315.8 KII90377.1 - 0.011 16.0 3.1 0.29 11.3 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 Seryl_tRNA_N PF02403.22 KII90377.1 - 0.02 15.1 1.1 3.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain XkdW PF09636.10 KII90377.1 - 0.025 14.6 1.2 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 XkdW protein LXG PF04740.12 KII90377.1 - 0.027 14.2 4.1 0.77 9.4 0.4 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Omp_AT PF11557.8 KII90377.1 - 0.053 12.5 0.3 0.11 11.4 0.2 1.5 2 0 0 2 2 2 0 Solitary outer membrane autotransporter beta-barrel domain Spc7 PF08317.11 KII90377.1 - 0.065 12.1 6.8 0.097 11.5 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Gly_radical PF01228.21 KII90377.1 - 0.069 13.7 1.1 0.26 11.9 0.3 1.9 2 0 0 2 2 2 0 Glycine radical IL6 PF00489.17 KII90377.1 - 0.076 12.6 3.8 0.072 12.6 1.6 1.8 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family DUF1664 PF07889.12 KII90377.1 - 0.087 12.9 4.4 3.5 7.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KII90377.1 - 0.095 13.1 3.4 7.2 7.1 0.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 KII90377.1 - 0.17 11.7 3.4 4.4 7.2 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.12 KII90377.1 - 0.31 11.1 6.8 2.7 8.0 0.6 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.11 KII90377.1 - 0.45 10.8 4.1 3.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 KII90377.1 - 0.52 10.7 5.3 5.9 7.3 0.6 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 KII90377.1 - 0.85 10.3 6.4 8.3 7.1 0.2 2.5 2 0 0 2 2 2 0 SlyX DUF4407 PF14362.6 KII90377.1 - 0.95 8.7 6.2 7.5 5.8 6.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 KII90377.1 - 1.6 9.3 8.0 0.78 10.3 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 GIT_CC PF16559.5 KII90377.1 - 2.3 8.2 8.4 1.1 9.2 1.2 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2347 PF09804.9 KII90378.1 - 1.4e-44 152.8 0.0 3e-44 151.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 KII90378.1 - 2.1e-05 23.4 0.0 2.2 6.9 0.0 3.1 3 0 0 3 3 3 3 Transport protein Avl9 Pkinase PF00069.25 KII90379.1 - 3.3e-05 23.4 0.0 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90379.1 - 0.012 14.9 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.14 KII90380.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII90380.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KII90380.1 - 0.2 11.0 0.1 0.87 8.9 0.1 1.8 1 1 0 1 1 1 0 Protein kinase domain ATP_bind_1 PF03029.17 KII90383.1 - 9.6e-73 244.9 0.0 1.4e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KII90383.1 - 0.00025 20.6 0.0 0.092 12.3 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KII90383.1 - 0.0011 19.2 0.0 0.0029 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KII90383.1 - 0.002 18.2 0.0 0.0097 16.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KII90383.1 - 0.0027 16.7 0.0 1.9 7.4 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KII90383.1 - 0.0028 17.6 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 KII90383.1 - 0.0044 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KII90383.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 KII90383.1 - 0.017 14.3 0.1 0.82 8.8 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 KII90383.1 - 0.021 14.4 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.19 KII90383.1 - 0.046 13.3 0.0 8.3 6.0 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KII90383.1 - 0.047 13.0 0.4 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 KII90383.1 - 0.048 13.3 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KII90383.1 - 0.061 13.2 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KII90383.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KII90383.1 - 0.11 12.8 0.0 0.88 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 KII90383.1 - 0.14 11.6 0.0 0.84 9.1 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_30 PF13604.6 KII90383.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII90383.1 - 0.18 12.3 0.3 2 8.9 0.0 2.7 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.25 KII90384.1 - 1e-74 251.3 0.0 1.1e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90384.1 - 3.2e-33 115.1 0.0 3.9e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII90384.1 - 7.3e-05 21.9 0.2 0.0012 17.8 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII90384.1 - 0.0016 18.4 0.2 0.012 15.5 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII90384.1 - 0.0082 15.5 0.0 0.18 11.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KII90384.1 - 0.033 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KII90385.1 - 3.6e-74 249.4 0.0 4.1e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90385.1 - 3e-33 115.2 0.0 3.6e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII90385.1 - 3.4e-05 23.0 0.1 0.00025 20.1 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII90385.1 - 0.00073 19.5 0.2 0.012 15.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII90385.1 - 0.017 14.4 0.0 0.18 11.1 0.0 2.1 1 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 KII90385.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KII90385.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KII90385.1 - 0.18 11.1 0.4 0.59 9.5 0.4 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3435 PF11917.8 KII90386.1 - 5.8e-05 22.2 0.0 0.00016 20.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Virul_fac_BrkB PF03631.15 KII90389.1 - 0.066 12.8 0.2 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Virulence factor BrkB Claudin_2 PF13903.6 KII90389.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase_Tyr PF07714.17 KII90391.1 - 2e-10 40.4 0.0 3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90391.1 - 2.8e-06 26.9 0.0 3.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KII90391.1 - 0.0089 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII90391.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FHA PF00498.26 KII90393.1 - 1.1e-08 35.2 0.0 2.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain NPV_P10 PF05531.12 KII90393.1 - 0.0021 18.5 2.3 0.056 13.9 0.1 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KII90393.1 - 0.0046 17.0 3.4 0.0076 16.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KII90393.1 - 0.01 15.9 0.4 0.056 13.5 0.2 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 KII90393.1 - 0.013 13.8 3.4 0.03 12.5 3.4 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA COG7 PF10191.9 KII90393.1 - 0.016 13.4 0.0 0.029 12.6 0.0 1.3 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) TPR_MLP1_2 PF07926.12 KII90393.1 - 0.04 14.0 0.5 0.04 14.0 0.5 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KII90393.1 - 0.045 14.0 1.0 0.2 11.9 1.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Leu_zip PF15294.6 KII90393.1 - 0.057 12.9 2.3 0.1 12.1 2.3 1.3 1 0 0 1 1 1 0 Leucine zipper FlxA PF14282.6 KII90393.1 - 0.074 13.1 5.5 0.75 9.8 0.1 3.1 2 1 1 3 3 3 0 FlxA-like protein CCDC144C PF14915.6 KII90393.1 - 0.085 12.0 3.1 0.19 10.8 0.3 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Baculo_F PF12259.8 KII90393.1 - 0.098 11.2 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Baculovirus F protein Syntaxin PF00804.25 KII90393.1 - 0.12 12.0 2.8 3.3 7.3 0.4 2.4 2 0 0 2 2 2 0 Syntaxin Prefoldin_2 PF01920.20 KII90393.1 - 0.16 11.9 1.4 3.9 7.5 0.1 3.0 2 2 0 2 2 2 0 Prefoldin subunit GAS PF13851.6 KII90393.1 - 0.17 11.2 4.4 0.27 10.6 0.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tmemb_cc2 PF10267.9 KII90393.1 - 0.17 11.0 3.4 0.15 11.2 0.5 2.2 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Syntaxin-6_N PF09177.11 KII90393.1 - 0.17 12.4 2.3 6.7 7.3 0.2 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SKA2 PF16740.5 KII90393.1 - 0.3 10.9 3.6 0.53 10.1 0.3 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 KII90393.1 - 0.34 9.8 5.3 0.57 9.0 4.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4515 PF14988.6 KII90393.1 - 0.38 10.6 5.6 0.68 9.7 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF883 PF05957.13 KII90393.1 - 0.53 10.9 8.3 1.7 9.3 1.5 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FliJ PF02050.16 KII90393.1 - 2.2 8.5 5.3 2.1 8.6 0.8 2.6 1 1 2 3 3 3 0 Flagellar FliJ protein DUF4140 PF13600.6 KII90393.1 - 3.8 8.0 5.9 4.1 7.9 1.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LPP PF04728.13 KII90393.1 - 5.9 7.4 8.7 20 5.6 0.1 4.2 5 0 0 5 5 5 0 Lipoprotein leucine-zipper SAC3_GANP PF03399.16 KII90394.1 - 1.7e-64 218.0 0.1 2.6e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family DUF29 PF01724.16 KII90394.1 - 0.12 12.6 0.5 0.34 11.1 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF29 Fer4_17 PF13534.6 KII90394.1 - 0.22 12.1 0.0 0.67 10.5 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Glyco_hydro_16 PF00722.21 KII90396.1 - 5.6e-16 58.5 0.2 1.1e-15 57.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KII90397.1 - 2.1e-56 191.0 0.3 2.1e-56 191.0 0.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KII90397.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KII90397.1 - 0.0039 17.0 0.0 0.077 12.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Gti1_Pac2 PF09729.9 KII90398.1 - 4.5e-58 196.3 0.0 1.2e-57 194.9 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family Peptidase_M22 PF00814.25 KII90399.1 - 1.4e-69 234.9 0.1 1.6e-69 234.6 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KII90399.1 - 0.0036 17.0 0.2 2.3 7.8 0.1 2.6 2 1 1 3 3 3 2 Carbamoyltransferase N-terminus Pkinase PF00069.25 KII90400.1 - 3.3e-31 108.6 0.0 4.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90400.1 - 5.5e-30 104.5 0.0 7.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII90400.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII90400.1 - 0.0044 17.0 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII90400.1 - 0.0046 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KII90400.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KII90401.1 - 1.2e-38 132.9 0.0 1.6e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90401.1 - 1.2e-29 103.5 0.0 1.5e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII90401.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII90401.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII90401.1 - 0.0068 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII90401.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KII90401.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 KII90401.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KII90401.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain MMR_HSR1 PF01926.23 KII90402.1 - 4e-18 65.5 0.1 7.7e-15 55.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KII90402.1 - 2.6e-08 33.6 0.1 1.5e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KII90402.1 - 1.3e-07 31.7 0.0 6.1e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KII90402.1 - 3.7e-05 23.3 0.0 0.0024 17.4 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KII90402.1 - 0.00021 21.4 0.6 0.44 10.6 0.2 3.2 2 1 1 3 3 3 1 Dynamin family MeaB PF03308.16 KII90402.1 - 0.00042 19.4 0.0 0.00087 18.4 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KII90402.1 - 0.0041 17.5 0.1 0.3 11.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Virul_Fac PF10139.9 KII90402.1 - 0.022 13.0 0.0 0.039 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative bacterial virulence factor Roc PF08477.13 KII90402.1 - 0.027 14.7 0.1 9 6.5 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KII90402.1 - 0.037 13.6 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 KII90402.1 - 0.046 13.1 0.3 0.22 10.8 0.2 2.0 2 0 0 2 2 2 0 AIG1 family Inositol_P PF00459.25 KII90404.1 - 9.1e-50 169.7 0.0 3.4e-49 167.8 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Pkinase_Tyr PF07714.17 KII90405.1 - 1.7e-35 122.6 0.0 2.1e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90405.1 - 6.5e-35 120.8 0.0 8.4e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KII90405.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 KII90405.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KII90405.1 - 0.075 12.4 0.2 0.28 10.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dict-STAT-coil PF09267.10 KII90405.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Pkinase_Tyr PF07714.17 KII90406.1 - 8.4e-41 139.9 0.0 1e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90406.1 - 1.1e-31 110.2 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.11 KII90406.1 - 0.0021 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 DUF1189 PF06691.11 KII90407.1 - 2.1 7.8 3.2 3.4 7.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) DEAD PF00270.29 KII90408.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.32 KII90409.1 - 7.4e-21 74.1 21.2 5.6e-05 23.8 0.5 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90409.1 - 2.8e-07 30.7 5.6 0.087 13.1 0.1 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII90409.1 - 3.1e-05 23.1 0.0 0.55 9.1 0.0 3.8 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein GTP_EFTU PF00009.27 KII90410.1 - 3.8e-59 199.5 0.0 5.9e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KII90410.1 - 3.3e-37 127.0 0.1 9e-37 125.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 KII90410.1 - 2e-28 98.3 0.0 4.1e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KII90410.1 - 5.6e-22 77.6 0.0 1.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KII90410.1 - 6.6e-13 48.9 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KII90410.1 - 1.3e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KII90410.1 - 0.025 14.7 0.0 0.087 12.9 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 KII90411.1 - 4e-34 118.2 0.0 5.6e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90411.1 - 1.8e-33 115.9 0.0 3.1e-33 115.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII90411.1 - 0.00012 22.1 0.2 0.00032 20.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII90411.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KII90411.1 - 0.0019 17.3 0.1 0.0029 16.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 KII90411.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family ABC1 PF03109.16 KII90411.1 - 0.0078 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family YrbL-PhoP_reg PF10707.9 KII90411.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 KII90411.1 - 0.064 12.6 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 KII90411.1 - 0.16 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1242 PF06842.12 KII90412.1 - 5.4e-18 64.5 1.7 7.8e-18 64.0 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 KII90412.1 - 0.068 13.5 0.4 0.21 11.9 0.4 1.7 2 0 0 2 2 2 0 LST-1 protein OPT PF03169.15 KII90413.1 - 1.8e-194 647.9 64.2 2.1e-194 647.7 64.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CrgA PF06781.12 KII90413.1 - 8.5 6.5 13.1 0.94 9.6 0.4 4.4 4 0 0 4 4 4 0 Cell division protein CrgA Nitrate_red_gam PF02665.14 KII90417.1 - 0.00024 20.7 0.6 0.00035 20.2 0.4 1.3 1 1 0 1 1 1 1 Nitrate reductase gamma subunit Syndecan PF01034.20 KII90417.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain AftA_N PF12250.8 KII90417.1 - 0.0033 16.3 0.2 0.0039 16.0 0.2 1.1 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal ASFV_J13L PF05568.11 KII90417.1 - 0.0088 15.8 0.2 0.013 15.3 0.1 1.4 1 1 0 1 1 1 1 African swine fever virus J13L protein EphA2_TM PF14575.6 KII90417.1 - 0.013 16.3 0.0 0.028 15.3 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 KII90417.1 - 0.03 14.5 0.6 0.051 13.8 0.6 1.5 1 1 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 KII90417.1 - 0.035 13.9 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 KII90417.1 - 0.089 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protocadherin 7tm_3 PF00003.22 KII90417.1 - 0.093 12.4 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Fusion_gly_K PF01621.17 KII90417.1 - 0.11 11.5 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Cell fusion glycoprotein K YajC PF02699.15 KII90417.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4381 PF14316.6 KII90417.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5305 PF17231.2 KII90417.1 - 0.23 10.8 0.0 0.26 10.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) FeoB_associated PF12669.7 KII90417.1 - 0.25 11.8 3.4 1 9.8 1.7 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Caudo_bapla_RBP PF08931.10 KII90418.1 - 0.095 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head YibE_F PF07907.11 KII90419.1 - 0.021 14.3 4.2 0.027 13.9 0.4 2.2 2 0 0 2 2 2 0 YibE/F-like protein Hydantoinase_A PF01968.18 KII90420.1 - 8.2e-96 320.7 0.0 1.4e-95 319.9 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KII90420.1 - 5.6e-59 198.8 0.2 6.4e-56 188.9 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF1708 PF08101.11 KII90421.1 - 7.4e-23 81.4 0.0 3.3e-19 69.4 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) zf-Di19 PF05605.12 KII90423.1 - 0.0003 21.0 1.2 0.0003 21.0 1.2 1.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KII90423.1 - 0.15 13.0 8.3 0.28 12.2 1.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KII90423.1 - 1.6 9.4 6.0 0.4 11.3 0.4 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_12 PF18658.1 KII90423.1 - 2.5 7.7 4.0 1.1 8.8 0.7 2.1 2 1 1 3 3 3 0 Zinc-finger C2H2-type MIF4G_like PF09088.11 KII90424.1 - 0.17 11.7 0.2 0.25 11.1 0.2 1.2 1 0 0 1 1 1 0 MIF4G like zf-C2H2 PF00096.26 KII90425.1 - 0.0073 16.7 0.1 0.0073 16.7 0.1 2.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KII90425.1 - 0.016 15.8 4.6 0.13 12.9 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KII90425.1 - 0.016 16.0 0.1 0.016 16.0 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII90425.1 - 0.18 12.3 1.6 9 6.9 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger double domain TMEM171 PF15471.6 KII90425.1 - 0.59 9.1 1.6 0.86 8.5 1.6 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 RNase_PH PF01138.21 KII90426.1 - 2.5e-16 60.4 0.1 3.7e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KII90426.1 - 8.4e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.16 KII90427.1 - 8.4e-18 64.7 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Trm112p-like protein Plavaka PF18759.1 KII90428.1 - 3.3e-102 342.0 0.1 5.2e-66 223.1 0.0 2.1 1 1 1 2 2 2 2 Plavaka transposase CDC45 PF02724.14 KII90428.1 - 1.1 7.5 7.2 1.6 7.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 KII90429.1 - 9.1 6.7 22.7 4.7 7.7 6.8 3.6 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DDE_3 PF13358.6 KII90431.1 - 1.4e-05 24.9 0.0 0.0092 15.7 0.0 3.2 3 0 0 3 3 3 2 DDE superfamily endonuclease Exonuc_V_gamma PF04257.14 KII90431.1 - 0.1 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit AhpC-TSA PF00578.21 KII90432.1 - 1.4e-32 112.3 0.0 1.8e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII90432.1 - 6.7e-12 45.3 0.0 8.7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KII90432.1 - 1.2e-10 41.1 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Glyco_transf_9 PF01075.17 KII90432.1 - 0.075 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Peptidase_M48 PF01435.18 KII90433.1 - 2.1e-26 92.9 0.1 1.7e-25 89.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M48 Terminase_6C PF17289.2 KII90433.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Terminase RNaseH-like domain SR-25 PF10500.9 KII90434.1 - 0.00025 20.8 10.2 0.00041 20.0 10.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein YL1 PF05764.13 KII90434.1 - 0.02 15.0 11.6 0.033 14.3 11.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein GBP_C PF02841.14 KII90434.1 - 0.16 11.4 8.2 0.3 10.4 8.2 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4614 PF15391.6 KII90434.1 - 0.25 11.3 5.0 0.42 10.6 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Rota_NSP4 PF01452.16 KII90434.1 - 0.33 10.6 3.7 0.48 10.1 2.1 2.0 2 0 0 2 2 2 0 Rotavirus non structural protein Neur_chan_memb PF02932.16 KII90434.1 - 0.46 10.5 3.3 1.8 8.6 3.3 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KII90434.1 - 0.63 8.3 8.2 0.9 7.7 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0239 PF06783.11 KII90434.1 - 1.1 9.4 5.5 3.5 7.9 5.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) zf-CCHC PF00098.23 KII90434.1 - 2.9 8.1 11.1 0.29 11.3 4.6 2.2 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.29 KII90437.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KII90437.1 - 0.0045 16.6 0.2 0.0078 15.8 0.1 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain T4SS-DNA_transf PF02534.14 KII90437.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AAA_19 PF13245.6 KII90437.1 - 0.088 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KII90437.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NAD_binding_9 PF13454.6 KII90439.1 - 0.00023 21.2 0.0 0.001 19.1 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DUF3337 PF11816.8 KII90440.1 - 5.5e-48 163.1 0.0 9.1e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KII90440.1 - 1.2e-22 79.7 12.1 3e-05 24.7 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KII90440.1 - 0.013 14.2 4.5 0.04 12.6 0.2 3.1 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KII90440.1 - 0.019 13.9 0.6 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 KII90440.1 - 0.05 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KII90440.1 - 0.06 13.7 0.0 0.27 11.6 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CBM_20 PF00686.19 KII90441.1 - 5.4e-30 103.1 0.0 1.4e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase_C PF02806.18 KII90441.1 - 2.2e-14 53.7 0.0 6.4e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 KII90441.1 - 5.4e-13 49.2 0.4 2.9e-12 46.8 0.4 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Pkinase PF00069.25 KII90442.1 - 1.2e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII90442.1 - 3e-05 24.1 0.6 3.7e-05 23.8 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII90442.1 - 9.3e-05 21.8 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KII90443.1 - 1.4e-26 93.3 0.0 1.7e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90443.1 - 1.6e-24 86.7 0.0 2.2e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII90443.1 - 2.4e-05 23.8 0.0 3.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII90443.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Orn_DAP_Arg_deC PF00278.22 KII90443.1 - 0.17 12.1 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Pkinase_Tyr PF07714.17 KII90444.1 - 5.2e-23 81.7 0.0 6e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII90444.1 - 6.8e-18 65.0 0.0 8.2e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII90444.1 - 0.0046 16.3 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII90444.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Polysacc_deac_1 PF01522.21 KII90446.1 - 2.3e-26 92.1 0.0 3.8e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_88 PF07470.13 KII90447.1 - 1.8e-16 60.1 0.1 1.8e-16 60.1 0.1 1.9 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Macoilin PF09726.9 KII90447.1 - 0.055 12.0 5.9 0.064 11.8 5.9 1.1 1 0 0 1 1 1 0 Macoilin family MID_MedPIWI PF18296.1 KII90447.1 - 0.33 10.7 6.4 0.85 9.4 5.1 2.1 1 1 1 2 2 2 0 MID domain of medPIWI CytochromB561_N PF09786.9 KII90447.1 - 1.2 8.0 12.3 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome B561, N terminal PAP1 PF08601.10 KII90447.1 - 1.3 8.7 13.0 1.9 8.1 13.0 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Miga PF10265.9 KII90447.1 - 2.1 7.3 6.8 2.8 6.8 6.8 1.1 1 0 0 1 1 1 0 Mitoguardin Presenilin PF01080.17 KII90447.1 - 2.2 7.0 5.1 3.3 6.4 5.1 1.2 1 0 0 1 1 1 0 Presenilin Tmemb_cc2 PF10267.9 KII90447.1 - 2.2 7.4 4.5 2.9 6.9 4.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Apt1 PF10351.9 KII90447.1 - 3.3 6.5 9.1 4.7 6.0 9.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 KII90447.1 - 3.9 5.6 15.5 5.1 5.3 15.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FSA_C PF10479.9 KII90447.1 - 6.3 4.8 12.7 8.8 4.3 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF262 PF03235.14 KII90448.1 - 1.2e-15 58.3 0.1 2.1e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF262 Apt1 PF10351.9 KII90448.1 - 0.035 13.0 3.7 0.058 12.3 3.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SMC_N PF02463.19 KII90449.1 - 7.4e-66 221.7 0.0 3.2e-65 219.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KII90449.1 - 2.5e-20 72.9 0.8 2.1e-19 70.0 0.1 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KII90449.1 - 2.3e-11 44.0 2.2 4.2e-05 23.5 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII90449.1 - 1.3e-05 24.8 0.2 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KII90449.1 - 3.3e-05 23.8 28.3 9.4e-05 22.3 3.4 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KII90449.1 - 3.9e-05 24.2 30.8 3.9e-05 24.2 30.8 6.3 2 2 0 2 2 1 1 AAA domain CENP-F_leu_zip PF10473.9 KII90449.1 - 0.0034 17.4 3.8 0.0034 17.4 3.8 7.9 4 2 3 7 7 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KII90449.1 - 0.0042 16.0 20.7 0.0042 16.0 20.7 6.5 3 2 3 6 6 6 4 Spc7 kinetochore protein KLRAQ PF10205.9 KII90449.1 - 0.0071 16.6 1.3 0.0071 16.6 1.3 6.3 5 1 2 7 7 6 1 Predicted coiled-coil domain-containing protein XhlA PF10779.9 KII90449.1 - 0.015 15.5 4.9 0.015 15.5 4.9 6.8 7 1 0 7 7 6 0 Haemolysin XhlA ABC_tran PF00005.27 KII90449.1 - 0.13 12.8 24.9 11 6.5 5.4 5.6 3 2 0 3 3 3 0 ABC transporter DUF4407 PF14362.6 KII90449.1 - 4.8 6.4 68.1 0.73 9.1 0.5 5.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4407) NIF PF03031.18 KII90450.1 - 1.1e-10 41.4 0.0 1.9e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRF1 PF07741.13 KII90450.1 - 0.048 14.0 0.9 0.13 12.6 0.9 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pro_isomerase PF00160.21 KII90451.1 - 3.4e-47 160.6 0.7 3.9e-47 160.5 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HAD PF12710.7 KII90452.1 - 0.13 12.7 0.1 0.25 11.7 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2116 PF09889.9 KII90452.1 - 0.48 10.4 3.3 1.2 9.2 3.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pox_F17 PF04767.12 KII90453.1 - 0.054 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein DUF2197 PF09963.9 KII90453.1 - 7.2 7.0 6.8 5.4 7.4 2.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DnaJ_CXXCXGXG PF00684.19 KII90454.1 - 3.8 7.9 13.3 2.3 8.7 0.4 3.3 3 0 0 3 3 3 0 DnaJ central domain DUF262 PF03235.14 KII90455.1 - 1.2e-17 64.9 0.7 2.8e-17 63.6 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 MAD PF05557.13 KII90456.1 - 1.2e-46 159.4 65.1 6.9e-46 156.9 65.1 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Glyco_trans_1_4 PF13692.6 KII90457.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferases group 1 LamB_YcsF PF03746.16 KII90458.1 - 4.2e-83 278.7 0.0 4.7e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AF-4 PF05110.13 KII90459.1 - 0.023 12.8 3.7 0.049 11.7 3.7 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF5447 PF17525.2 KII90459.1 - 1 9.9 8.1 14 6.3 3.4 3.4 2 0 0 2 2 2 0 Family of unknown function (DUF5447) zf-ACC PF17848.1 KII90459.1 - 4.6 7.4 10.5 2.5 8.3 1.2 3.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain F-box-like PF12937.7 KII90460.1 - 3.3e-05 23.7 0.1 9.1e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII90460.1 - 0.012 15.5 3.8 0.016 15.1 0.5 2.8 2 1 0 2 2 2 0 F-box domain CT_A_B PF02626.15 KII90461.1 - 3.8e-70 236.5 0.0 6.6e-70 235.7 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KII90461.1 - 1.5e-60 204.3 0.0 3.4e-60 203.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KII90461.1 - 4.8e-37 126.9 0.1 3.8e-36 124.0 0.1 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KII90461.1 - 5.4e-33 114.4 0.0 1.5e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KII90461.1 - 8e-29 99.9 0.0 1.5e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KII90461.1 - 2.2e-08 33.9 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KII90461.1 - 0.0096 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.22 KII90461.1 - 0.013 15.4 0.1 0.034 14.0 0.1 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KII90461.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KII90461.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Glyco_hydro_16 PF00722.21 KII90462.1 - 0.0004 19.9 0.0 0.0096 15.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KII90463.1 - 0.0029 17.1 0.0 0.0072 15.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ORF11CD3 PF10549.9 KII90464.1 - 2.6 8.2 7.7 2.2e+02 2.1 0.1 4.8 5 0 0 5 5 5 0 ORF11CD3 domain Hydrolase_like PF13242.6 KII90466.1 - 0.62 10.2 16.8 77 3.5 0.1 7.3 7 0 0 7 7 7 0 HAD-hyrolase-like Lig_C PF18330.1 KII90466.1 - 2.7 8.0 5.6 1.2e+02 2.7 0.0 4.0 4 0 0 4 4 4 0 Ligase Pab1020 C-terminal region DUF2964 PF11177.8 KII90467.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) DUF2677 PF10838.8 KII90469.1 - 0.033 14.2 0.8 0.17 11.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2677) CybS PF05328.12 KII90471.1 - 6.1e-37 126.3 0.0 7.2e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Glyco_transf_11 PF01531.16 KII90472.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 11 SCP1201-deam PF14428.6 KII90472.1 - 0.5 10.2 5.1 0.22 11.4 1.4 2.1 1 1 1 2 2 2 0 SCP1.201-like deaminase OrfB_IS605 PF01385.19 KII90474.1 - 0.072 13.3 0.8 0.13 12.5 0.7 1.6 1 1 0 1 1 1 0 Probable transposase Hus1 PF04005.12 KII90481.1 - 2.2e-52 178.0 0.0 2.5e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Crystall_4 PF17945.1 KII90481.1 - 0.085 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Imp-YgjV PF10688.9 KII90484.1 - 0.71 9.7 11.8 0.098 12.5 5.2 2.2 2 0 0 2 2 2 0 Bacterial inner membrane protein F-box-like PF12937.7 KII90485.1 - 2.1e-06 27.5 0.0 1.5e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 F-box-like DUF1758 PF05585.12 KII90486.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) PgpA PF04608.13 KII90487.1 - 0.082 12.9 5.8 0.17 11.9 1.6 2.3 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A DUF2568 PF10823.8 KII90488.1 - 0.00074 19.8 0.0 0.003 17.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2568) DUF983 PF06170.12 KII90488.1 - 0.61 10.5 4.9 0.9 10.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) PNP_UDP_1 PF01048.20 KII90489.1 - 1.2e-33 116.3 0.1 1.4e-33 116.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily VPS28 PF03997.12 KII90492.1 - 8.1e-72 240.9 0.0 9.3e-72 240.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Coronavirus_5 PF05528.11 KII90492.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Coronavirus gene 5 protein DNA_ligase_OB_2 PF14743.6 KII90494.1 - 3.6e-26 91.0 0.5 3.6e-26 91.0 0.5 2.0 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 KII90494.1 - 2e-10 40.7 0.0 8.3e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KII90494.1 - 3e-07 30.9 0.0 1.3e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 RNA ligase SWIM PF04434.17 KII90494.1 - 9.8e-06 25.1 1.9 0.087 12.5 0.2 2.6 2 0 0 2 2 2 2 SWIM zinc finger RecO_C PF02565.15 KII90494.1 - 0.14 12.0 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Recombination protein O C terminal CDC27 PF09507.10 KII90494.1 - 3.5 6.9 50.2 0.45 9.9 45.3 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cpn60_TCP1 PF00118.24 KII90495.1 - 6e-85 285.7 4.5 1e-84 284.9 4.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.18 KII90496.1 - 7.1e-22 77.7 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII90496.1 - 6.8e-09 35.7 11.2 1.4e-08 34.7 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain polyprenyl_synt PF00348.17 KII90497.1 - 1.7e-92 309.1 0.0 2.1e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase zf-MYND PF01753.18 KII90499.1 - 7.4e-09 35.6 22.0 1.7e-08 34.4 22.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII90499.1 - 0.0067 16.7 12.6 0.013 15.8 12.6 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KII90499.1 - 1.7 8.8 9.5 3.3 7.9 9.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KII90500.1 - 6.6e-09 35.7 15.7 1.6e-08 34.5 15.7 1.7 1 1 0 1 1 1 1 MYND finger DUF4279 PF14106.6 KII90500.1 - 0.0039 17.4 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4279) zf-C6H2 PF15801.5 KII90500.1 - 0.023 15.0 10.5 0.039 14.3 10.5 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DnaJ PF00226.31 KII90501.1 - 9.4e-19 67.3 1.6 1.1e-18 67.1 0.1 2.0 2 0 0 2 2 1 1 DnaJ domain TPR_1 PF00515.28 KII90501.1 - 1.2e-15 56.6 10.1 0.00016 21.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII90501.1 - 1.5e-14 52.9 18.2 0.00018 21.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII90501.1 - 6.7e-10 39.3 19.7 0.0072 16.8 0.4 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KII90501.1 - 1.5e-09 38.3 28.7 1.1e-07 32.4 0.8 6.5 3 2 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII90501.1 - 1.7e-07 31.5 9.3 0.25 11.7 0.0 5.9 5 3 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KII90501.1 - 1e-06 28.3 5.3 4e-06 26.4 0.9 4.1 4 1 1 5 5 5 1 TPR repeat TPR_9 PF13371.6 KII90501.1 - 1.4e-06 28.4 10.3 0.11 12.6 0.3 5.2 3 2 3 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KII90501.1 - 2.1e-06 27.9 12.9 0.0025 18.0 1.4 4.6 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KII90501.1 - 4.3e-06 26.4 0.2 0.32 11.1 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII90501.1 - 3.5e-05 24.3 23.7 0.0067 17.2 0.3 7.2 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII90501.1 - 5.4e-05 23.1 11.0 0.34 11.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII90501.1 - 5.5e-05 23.5 15.5 11 7.0 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 KII90501.1 - 0.00012 22.2 7.0 0.058 13.8 0.3 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat FANC_SAP PF18081.1 KII90501.1 - 0.0015 18.7 2.6 0.12 12.6 0.2 3.4 3 0 0 3 3 3 1 Fanconi anemia-associated nuclease SAP domain TPR_10 PF13374.6 KII90501.1 - 0.0025 17.6 0.7 13 5.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 KII90501.1 - 0.013 14.2 0.1 0.062 12.0 0.0 2.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3808) BTAD PF03704.17 KII90501.1 - 0.028 14.9 13.3 0.73 10.3 0.0 5.1 5 1 0 5 5 5 0 Bacterial transcriptional activator domain MIT PF04212.18 KII90501.1 - 0.37 10.9 4.0 7 6.8 0.0 4.1 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TetR_C_7 PF14246.6 KII90501.1 - 1.8 8.6 5.4 0.35 10.9 0.1 2.5 2 2 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Zn_clus PF00172.18 KII90502.1 - 1.9e-06 27.9 12.3 3.8e-06 26.9 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII90502.1 - 0.00038 19.6 0.5 0.00097 18.2 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Levi_coat PF01819.17 KII90502.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Levivirus coat protein Tetraspanin PF00335.20 KII90504.1 - 0.041 13.6 10.4 0.027 14.2 8.9 1.3 1 1 0 1 1 1 0 Tetraspanin family NKAIN PF05640.14 KII90504.1 - 0.18 11.0 4.2 0.83 8.9 3.2 2.2 1 1 1 2 2 2 0 Na,K-Atpase Interacting protein ABC2_membrane_2 PF12679.7 KII90504.1 - 0.6 9.3 5.9 0.57 9.4 3.7 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein GRP PF07172.11 KII90505.1 - 0.0081 16.8 0.3 0.031 15.0 0.3 2.0 1 0 0 1 1 1 1 Glycine rich protein family CRAL_TRIO PF00650.20 KII90507.1 - 1.4e-24 86.6 0.0 3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII90507.1 - 3.2e-07 30.4 0.8 6.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain UPF0203 PF05254.12 KII90508.1 - 1.1e-24 86.4 0.3 1.6e-24 85.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 KII90508.1 - 0.1 12.8 2.1 3.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein ADH_N PF08240.12 KII90509.1 - 5.7e-29 100.2 3.3 5.7e-29 100.2 3.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII90509.1 - 8.4e-21 74.3 0.1 1.5e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII90509.1 - 8.1e-07 28.7 1.1 2.6e-06 27.1 1.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII90509.1 - 0.0001 23.3 0.1 0.00017 22.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KII90509.1 - 0.003 16.9 1.1 0.0074 15.6 1.1 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KII90509.1 - 0.0036 17.6 0.1 0.0063 16.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 KII90509.1 - 0.037 13.2 0.3 0.065 12.4 0.3 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Nipped-B_C PF12830.7 KII90510.1 - 1.6e-53 181.5 2.0 5.3e-53 179.8 2.0 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KII90510.1 - 2.7e-15 56.4 0.5 1.4e-13 50.9 0.1 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KII90510.1 - 0.0001 22.2 0.3 0.83 10.1 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KII90510.1 - 0.00022 21.6 4.9 0.0072 16.7 0.2 4.4 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KII90510.1 - 0.0035 17.8 2.5 3.2 8.4 0.1 4.6 3 1 1 4 4 4 1 HEAT-like repeat Aldo_ket_red PF00248.21 KII90511.1 - 4.9e-67 226.2 0.1 5.5e-67 226.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HA2 PF04408.23 KII90512.1 - 2.2e-20 72.9 0.0 5e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KII90512.1 - 3.7e-14 53.0 0.0 8.3e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90512.1 - 6.2e-07 29.3 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KII90512.1 - 2.1e-06 28.0 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KII90512.1 - 0.00011 22.4 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII90512.1 - 0.006 16.3 0.2 0.012 15.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII90512.1 - 0.042 14.2 0.1 0.091 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 KII90512.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 KII90512.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 KII90512.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 KII90512.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DIOX_N PF14226.6 KII90513.1 - 4.6e-32 111.2 0.0 6.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII90513.1 - 2.3e-20 73.0 0.0 4.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0172 PF03665.13 KII90514.1 - 2.6e-55 187.5 0.0 2.9e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 KII90514.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cep57_MT_bd PF06657.13 KII90515.1 - 1.8e-24 86.0 0.2 1.8e-24 86.0 0.2 3.8 2 1 1 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KII90515.1 - 1.4e-10 41.1 9.5 1.4e-10 41.1 9.5 3.1 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Pox_A_type_inc PF04508.12 KII90515.1 - 0.0068 16.2 3.6 0.0068 16.2 3.6 4.1 3 1 1 4 4 4 1 Viral A-type inclusion protein repeat IZUMO PF15005.6 KII90515.1 - 0.054 14.0 2.4 0.14 12.7 2.1 1.8 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated REF PF05755.12 KII90515.1 - 0.089 12.6 0.4 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) BLOC1_2 PF10046.9 KII90515.1 - 0.37 11.1 7.5 9.4 6.6 0.1 3.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 KII90515.1 - 0.82 9.7 3.9 3.3 7.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SKA2 PF16740.5 KII90515.1 - 2.2 8.1 9.3 30 4.4 4.7 3.4 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 SAPS PF04499.15 KII90515.1 - 6.8 5.4 9.5 13 4.5 9.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TetR_C_24 PF17932.1 KII90515.1 - 9.1 6.6 8.4 0.66 10.2 1.8 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Hpt PF01627.23 KII90516.1 - 1.8e-08 34.5 0.2 3.3e-08 33.7 0.2 1.5 1 1 0 1 1 1 1 Hpt domain SpoVAD PF07451.11 KII90516.1 - 0.12 11.1 0.1 0.17 10.5 0.1 1.3 1 1 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) CoA_transf_3 PF02515.17 KII90517.1 - 5.2e-127 424.0 0.0 6e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Transket_pyr PF02779.24 KII90518.1 - 4.5e-66 221.9 0.0 7.5e-66 221.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KII90518.1 - 2e-60 204.3 0.0 3.1e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KII90518.1 - 2.2e-52 176.8 0.0 4e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KII90518.1 - 2.3e-19 68.7 0.4 4.9e-19 67.6 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Ribosomal_L23eN PF03939.13 KII90519.1 - 1.2e-20 73.5 11.5 1.2e-20 73.5 11.5 2.1 1 1 1 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KII90519.1 - 2.4e-15 56.6 0.7 2.4e-15 56.6 0.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 KII90519.1 - 0.00064 20.0 1.5 0.00087 19.6 1.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5451) DUF2070 PF09843.9 KII90520.1 - 3 6.0 10.6 4.6 5.4 10.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RIBIOP_C PF04950.12 KII90521.1 - 1.1e-94 317.2 0.0 1.1e-94 317.2 0.0 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KII90521.1 - 2.1e-29 101.4 0.9 4e-29 100.5 0.0 2.0 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KII90521.1 - 1.5e-05 25.4 0.0 5.2e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KII90521.1 - 2.8e-05 23.8 0.0 0.0091 15.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KII90521.1 - 5.6e-05 23.4 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KII90521.1 - 0.0002 21.4 0.1 0.00073 19.6 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KII90521.1 - 0.00021 21.4 0.0 0.00073 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KII90521.1 - 0.001 19.6 0.0 0.0068 17.0 0.0 2.5 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KII90521.1 - 0.0014 19.2 0.0 0.0014 19.2 0.0 2.1 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 KII90521.1 - 0.0022 17.9 0.2 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 KII90521.1 - 0.0024 18.3 0.1 0.0086 16.5 0.0 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII90521.1 - 0.0039 16.4 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KII90521.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KII90521.1 - 0.0091 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KII90521.1 - 0.0097 16.2 0.5 0.036 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KII90521.1 - 0.017 15.0 1.2 0.049 13.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 KII90521.1 - 0.029 14.1 0.0 0.099 12.4 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KII90521.1 - 0.05 13.3 0.0 0.05 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KII90521.1 - 0.051 13.5 0.3 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KII90521.1 - 0.07 13.2 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 KII90521.1 - 0.075 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KII90521.1 - 0.086 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 KII90521.1 - 0.1 12.5 0.0 0.46 10.4 0.0 2.1 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_5 PF07728.14 KII90521.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KII90521.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.12 KII90521.1 - 0.3 10.4 11.4 0.0074 15.7 4.2 2.1 2 0 0 2 2 1 0 Rtf2 RING-finger AAA_23 PF13476.6 KII90521.1 - 2.2 8.7 9.9 6.6 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Helicase_C_2 PF13307.6 KII90522.1 - 3.5e-54 183.5 0.0 7.4e-54 182.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KII90522.1 - 2.2e-42 144.7 0.0 3.2e-41 140.9 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KII90522.1 - 0.00057 19.9 0.0 0.26 11.3 0.0 2.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KII90522.1 - 0.0041 16.9 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII90522.1 - 0.0053 17.0 0.2 3 8.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 KII90522.1 - 0.0058 16.1 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein EAP30 PF04157.16 KII90522.1 - 0.034 13.4 1.0 0.07 12.4 0.1 1.8 2 0 0 2 2 2 0 EAP30/Vps36 family AAA_11 PF13086.6 KII90522.1 - 0.041 13.7 0.2 0.18 11.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KII90522.1 - 0.073 12.1 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KII90522.1 - 0.11 12.1 0.7 1.9 8.2 0.3 2.9 2 1 1 3 3 3 0 AAA domain His_Phos_1 PF00300.22 KII90523.1 - 3.6e-11 43.1 0.2 4.9e-09 36.2 0.2 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.21 KII90524.1 - 4.3e-64 216.5 0.0 4.9e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PCP_red PF08369.10 KII90524.1 - 0.28 11.4 1.8 3.2 8.0 0.2 3.0 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Ras PF00071.22 KII90525.1 - 1.1e-54 184.4 0.0 1.3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII90525.1 - 8.8e-22 77.6 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII90525.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KII90525.1 - 0.003 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KII90525.1 - 0.22 10.8 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Asp PF00026.23 KII90526.1 - 1.7e-36 126.3 0.5 2.7e-35 122.3 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII90526.1 - 1.1e-06 29.0 1.0 3.4e-05 24.2 1.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal AKAP7_NLS PF10469.9 KII90527.1 - 5.7e-27 95.0 0.0 6.1e-24 85.1 0.0 2.4 2 1 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain FAA_hydrolase_N PF09298.11 KII90527.1 - 0.049 13.8 0.0 0.22 11.7 0.0 2.0 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal Sugar_tr PF00083.24 KII90528.1 - 2.5e-44 151.9 11.9 4.1e-44 151.2 11.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90528.1 - 6.1e-22 78.0 20.6 6.2e-12 45.1 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KII90528.1 - 1.5e-05 23.5 2.7 0.00023 19.6 0.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Complex1_51K PF01512.17 KII90529.1 - 3.7e-48 163.2 0.0 5.7e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KII90529.1 - 6.8e-32 109.4 1.4 9.6e-32 108.9 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KII90529.1 - 8.6e-08 31.9 0.0 2.1e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KII90529.1 - 0.2 11.7 0.3 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) F-box-like PF12937.7 KII90530.1 - 1.3e-07 31.3 1.0 5.2e-07 29.5 1.0 2.1 1 0 0 1 1 1 1 F-box-like BTB PF00651.31 KII90531.1 - 8.9e-11 42.0 0.0 2.2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Helicase_C PF00271.31 KII90534.1 - 2.3e-16 60.1 0.0 6.2e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90534.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase SR-25 PF10500.9 KII90534.1 - 0.3 10.7 16.5 0.15 11.7 4.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RecQ_Zn_bind PF16124.5 KII90534.1 - 2 9.2 5.0 0.45 11.3 0.3 2.2 2 0 0 2 2 2 0 RecQ zinc-binding Gpi16 PF04113.14 KII90535.1 - 1.5e-142 475.9 0.0 1.4e-141 472.7 0.0 1.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component F1F0-ATPsyn_F PF10791.9 KII90536.1 - 5.2e-29 100.6 0.0 6e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi EB1 PF03271.17 KII90537.1 - 6.1e-17 61.6 1.2 1.2e-16 60.7 1.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KII90537.1 - 1.1e-05 25.5 0.6 2.3e-05 24.5 0.4 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 KII90537.1 - 0.079 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein Peptidase_S9 PF00326.21 KII90539.1 - 6.2e-49 166.3 0.6 8.9e-49 165.8 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KII90539.1 - 2.7e-05 23.9 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KII90539.1 - 0.00068 18.4 0.0 0.25 10.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.12 KII90539.1 - 0.055 13.4 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RL10P_insert PF17777.1 KII90540.1 - 7.8e-22 77.1 0.0 1.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KII90540.1 - 3.6e-19 68.8 0.0 5.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 HEAT_2 PF13646.6 KII90541.1 - 1.9e-34 117.9 1.0 2.5e-15 56.6 0.0 4.1 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KII90541.1 - 2.4e-26 89.7 0.1 0.00025 21.4 0.0 6.6 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KII90541.1 - 6.5e-11 41.5 0.1 0.0073 16.5 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 KII90541.1 - 2.9e-07 30.3 0.0 0.025 14.6 0.0 3.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KII90541.1 - 9.5e-06 26.0 0.6 0.27 11.8 0.1 4.5 3 1 1 4 4 4 2 HEAT-like repeat zf-CCCH_6 PF18585.1 KII90541.1 - 0.015 15.2 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF3385 PF11865.8 KII90541.1 - 0.09 12.7 0.0 9 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) DUF4858 PF16150.5 KII90543.1 - 0.19 11.8 0.2 0.31 11.0 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4858) Adaptin_binding PF10199.9 KII90545.1 - 1.1e-07 32.5 4.9 1.4e-07 32.1 2.5 2.2 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF4571 PF15137.6 KII90546.1 - 0.0077 15.9 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4571) T2SSE PF00437.20 KII90549.1 - 0.00039 19.6 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KII90549.1 - 0.0042 16.8 0.2 0.0042 16.8 0.2 2.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KII90549.1 - 0.017 15.4 0.0 0.083 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KII90549.1 - 0.019 14.7 0.4 0.069 12.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KII90549.1 - 0.03 14.7 2.3 0.078 13.3 0.2 2.3 2 1 0 2 2 2 0 AAA domain Herpes_ori_bp PF02399.15 KII90549.1 - 0.14 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein HpcH_HpaI PF03328.14 KII90550.1 - 1e-43 149.1 0.0 2.4e-43 147.8 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KII90550.1 - 6.1e-11 42.1 0.0 5e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CwfJ_C_2 PF04676.14 KII90551.1 - 4.7e-36 123.6 0.6 1.4e-34 118.9 0.0 3.0 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KII90551.1 - 3.8e-33 114.0 0.1 5.4e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Chitin_synth_1 PF01644.17 KII90552.1 - 8.2e-79 263.3 0.0 1.2e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KII90552.1 - 8.8e-29 99.3 0.0 1.9e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KII90552.1 - 2e-22 79.6 2.8 2.1e-17 62.9 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KII90552.1 - 0.0078 16.1 14.8 0.08 12.8 14.8 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 NmrA PF05368.13 KII90554.1 - 7e-38 130.5 0.0 1e-37 130.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII90554.1 - 3.1e-17 63.1 0.0 5.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII90554.1 - 9.7e-05 21.9 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII90554.1 - 0.041 12.9 0.0 0.084 11.9 0.0 1.6 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KII90554.1 - 0.047 12.9 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 KII90554.1 - 0.08 13.4 0.2 0.13 12.7 0.2 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.7 KII90555.1 - 0.0071 16.2 1.4 0.017 15.0 1.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII90555.1 - 0.011 15.6 1.3 0.022 14.6 0.0 2.2 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.25 KII90557.1 - 3e-05 23.5 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90557.1 - 0.042 13.1 0.0 0.084 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Rad50_zn_hook PF04423.14 KII90557.1 - 0.1 12.4 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Ecl1 PF12855.7 KII90559.1 - 0.022 15.9 10.9 0.022 15.9 10.9 5.6 2 1 3 5 5 5 0 ECL1/2/3 zinc binding proteins DUF1634 PF07843.11 KII90560.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Alpha-E PF04168.12 KII90563.1 - 0.035 13.9 5.3 0.033 14.0 4.4 1.4 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. CsbD PF05532.12 KII90564.1 - 2.2e-15 56.3 12.9 1.1e-09 38.0 3.0 2.1 1 1 1 2 2 2 2 CsbD-like FKBP_C PF00254.28 KII90565.1 - 4.6e-32 110.2 0.0 5.3e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase OGFr_N PF04664.13 KII90568.1 - 1.5e-56 191.3 0.0 2e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF727 PF05303.12 KII90569.1 - 8.8e-09 35.4 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Sec1 PF00995.23 KII90572.1 - 8.2e-123 411.6 0.0 1e-122 411.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 KII90572.1 - 6.3e-80 268.2 0.4 9.2e-80 267.6 0.4 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KII90572.1 - 1.8e-20 73.0 0.1 5.8e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SWC7 PF17330.2 KII90572.1 - 0.15 12.2 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 ERM PF00769.19 KII90573.1 - 0.00092 19.1 8.8 0.0018 18.1 8.8 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family FAM184 PF15665.5 KII90573.1 - 1.1 9.0 14.5 2.4 7.9 13.1 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B PPP4R2 PF09184.11 KII90573.1 - 1.5 8.3 9.7 0.054 13.1 3.7 1.7 2 0 0 2 2 2 0 PPP4R2 DUF3450 PF11932.8 KII90573.1 - 9.3 5.5 18.8 23 4.2 18.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TPP_enzyme_N PF02776.18 KII90574.1 - 6.5e-39 133.3 0.5 6.5e-39 133.3 0.5 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KII90574.1 - 1.9e-16 60.2 0.3 4.3e-16 59.0 0.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KII90574.1 - 0.00099 18.9 0.0 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.25 KII90575.1 - 2.6e-25 89.0 0.2 3.3e-25 88.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII90575.1 - 5.5e-19 68.7 0.4 6.3e-19 68.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90575.1 - 6.4e-06 26.2 0.1 8.6e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII90575.1 - 0.029 13.7 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KII90575.1 - 0.074 12.9 1.6 0.15 11.9 1.6 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Yae1_N PF09811.9 KII90576.1 - 1.7e-10 40.4 1.1 3.4e-10 39.5 1.1 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal eIF2A PF08662.11 KII90577.1 - 1.5e-07 31.5 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PVL_ORF50 PF07768.11 KII90579.1 - 3.6 7.9 7.5 7.5 6.9 7.5 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family Thaumatin PF00314.17 KII90580.1 - 1.2e-70 237.5 17.6 1.3e-70 237.3 17.6 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KII90580.1 - 0.0014 17.9 2.2 0.0024 17.2 0.1 2.0 2 1 0 2 2 2 1 Beta-1,3-glucanase Phage_tail_APC PF16778.5 KII90581.1 - 0.0072 16.2 0.1 0.062 13.2 0.0 2.0 2 0 0 2 2 2 1 Phage tail assembly chaperone protein DSPc PF00782.20 KII90583.1 - 8e-26 90.4 0.0 1e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KII90583.1 - 0.0094 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Adeno_E1B_19K PF01691.16 KII90583.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Alg6_Alg8 PF03155.15 KII90585.1 - 1.2e-136 456.6 14.8 1.7e-136 456.1 14.8 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 KII90585.1 - 0.14 11.6 4.4 0.18 11.2 0.9 2.3 1 1 1 2 2 2 0 ALG3 protein TRI5 PF06330.11 KII90586.1 - 2.6e-16 59.5 0.0 3e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) HTH_Tnp_Tc5 PF03221.16 KII90587.1 - 6.2e-06 26.1 0.1 1.2e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 KII90588.1 - 4.6e-15 55.7 0.0 9.1e-15 54.7 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 KII90588.1 - 0.003 17.3 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotran_gag_2 PF14223.6 KII90589.1 - 1.6e-15 57.0 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4710 PF15828.5 KII90590.1 - 0.61 10.2 3.8 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) PV-1 PF06637.11 KII90590.1 - 1.5 7.6 7.4 1.4 7.6 0.6 2.1 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Plavaka PF18759.1 KII90591.1 - 3.2e-131 437.4 0.0 4.3e-131 437.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Mito_carr PF00153.27 KII90594.1 - 1.4e-28 98.6 0.6 7.3e-11 41.9 0.0 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 KII90595.1 - 8.7e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain UL42 PF17638.2 KII90595.1 - 0.055 13.4 0.1 0.055 13.4 0.1 3.9 4 0 0 4 4 4 0 HCMV UL42 His_Phos_1 PF00300.22 KII90596.1 - 6.6e-15 55.3 2.6 1.7e-14 54.0 0.9 2.4 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SKN1 PF03935.15 KII90597.1 - 5.7e-192 638.6 1.1 6.6e-192 638.4 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) FGGY_N PF00370.21 KII90600.1 - 7.3e-23 81.4 0.0 3.2e-15 56.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KII90600.1 - 3.8e-18 65.9 0.0 6.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pro_isomerase PF00160.21 KII90601.1 - 6.9e-49 166.1 0.1 2.2e-48 164.5 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KII90601.1 - 8.1e-06 26.5 0.1 1 10.3 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4504 PF14953.6 KII90602.1 - 5.5e-06 26.0 1.2 0.00079 18.9 0.1 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4504) Pdase_M17_N2 PF18295.1 KII90603.1 - 0.037 14.3 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 RIO1 PF01163.22 KII90606.1 - 3.7e-72 241.9 0.0 3.7e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KII90606.1 - 0.0012 18.9 1.2 1.2 9.1 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family YL1 PF05764.13 KII90606.1 - 0.0077 16.4 21.1 0.035 14.2 8.8 2.3 2 0 0 2 2 2 2 YL1 nuclear protein Kdo PF06293.14 KII90606.1 - 0.014 14.8 0.8 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII90606.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain CDC45 PF02724.14 KII90606.1 - 0.98 7.6 17.5 0.36 9.1 8.5 2.1 2 0 0 2 2 2 0 CDC45-like protein ILVD_EDD PF00920.21 KII90607.1 - 1.7e-203 676.9 0.1 2e-203 676.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Zn_clus PF00172.18 KII90609.1 - 1.7e-07 31.2 5.2 1.7e-07 31.2 5.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_YhaV PF11663.8 KII90609.1 - 0.18 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Septin PF00735.18 KII90610.1 - 2.1e-30 106.0 0.0 2.2e-09 37.0 0.0 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 KII90610.1 - 1.4e-18 66.7 26.4 3.5e-10 39.8 7.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM-assoc_2 PF16496.5 KII90610.1 - 3.3 6.5 9.1 1.1 8.0 1.8 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Septin PF00735.18 KII90611.1 - 2.9e-46 158.0 0.0 2.5e-16 59.8 0.0 3.7 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.23 KII90611.1 - 5.5e-06 26.4 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII90611.1 - 1.4e-05 24.8 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain CM_2 PF01817.21 KII90612.1 - 1.2e-06 28.8 0.1 0.011 16.1 0.0 3.1 3 1 0 3 3 3 2 Chorismate mutase type II Thi4 PF01946.17 KII90613.1 - 1.7e-102 341.6 0.1 2.1e-102 341.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KII90613.1 - 6.3e-10 39.2 0.8 3.9e-09 36.5 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII90613.1 - 1e-06 28.1 0.5 6.2e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KII90613.1 - 1.2e-06 28.0 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII90613.1 - 1.4e-06 28.5 0.1 3.4e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KII90613.1 - 4.4e-06 26.8 1.7 6.8e-05 22.9 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KII90613.1 - 3.6e-05 23.0 1.0 0.00019 20.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII90613.1 - 0.0007 18.4 0.2 0.0013 17.5 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KII90613.1 - 0.004 16.6 0.2 0.0064 15.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KII90613.1 - 0.021 14.1 0.1 0.04 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII90613.1 - 0.023 13.8 0.3 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KII90613.1 - 0.026 13.4 0.4 0.038 12.8 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KII90613.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Nas2_N PF18265.1 KII90614.1 - 2e-25 88.5 0.0 2.7e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KII90614.1 - 6.3e-07 29.1 0.4 8.5e-06 25.5 0.1 2.7 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KII90614.1 - 7.2e-06 26.2 0.0 2.5e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 KII90614.1 - 2.8e-05 24.5 0.0 6e-05 23.4 0.0 1.7 2 1 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KII90614.1 - 0.032 14.6 0.0 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 PDZ domain AidB_N PF18158.1 KII90615.1 - 2.3e-28 99.1 0.0 4.1e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KII90615.1 - 2.5e-19 70.0 0.1 6.5e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII90615.1 - 6.4e-14 51.9 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KII90615.1 - 1e-06 29.1 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KII90615.1 - 0.0033 18.1 0.0 0.0089 16.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain F-box-like PF12937.7 KII90616.1 - 0.00049 19.9 0.6 0.0084 16.0 0.0 3.2 4 0 0 4 4 4 1 F-box-like LRR_8 PF13855.6 KII90616.1 - 0.0063 16.2 0.2 0.019 14.7 0.1 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KII90616.1 - 0.16 12.4 0.2 2.6 8.6 0.1 2.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) EPOP PF15223.6 KII90616.1 - 0.27 10.5 0.0 0.36 10.1 0.0 1.1 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein F-box-like PF12937.7 KII90617.1 - 1.2e-09 37.9 0.2 3.4e-09 36.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII90617.1 - 0.0011 18.8 0.1 0.0039 17.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain ChW PF07538.11 KII90617.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W Fungal_trans PF04082.18 KII90618.1 - 4.7e-29 101.2 0.0 7.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII90618.1 - 8.3e-10 38.6 8.8 2e-09 37.4 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Heme_oxygenase PF01126.20 KII90619.1 - 1.8e-29 103.0 0.1 2.3e-28 99.4 0.1 2.4 1 1 0 1 1 1 1 Heme oxygenase Glyco_trans_4_3 PF12000.8 KII90619.1 - 0.075 12.7 0.2 0.98 9.1 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 4 group Fungal_trans PF04082.18 KII90620.1 - 4.1e-28 98.2 0.1 4.1e-28 98.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII90620.1 - 0.00038 20.5 4.3 0.00079 19.5 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KII90622.1 - 1.2e-39 136.2 0.0 1.1e-32 113.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family F-box-like PF12937.7 KII90623.1 - 1.3e-08 34.5 1.4 3.5e-08 33.2 1.4 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII90623.1 - 0.0036 17.2 0.4 1 9.3 0.0 2.3 2 0 0 2 2 2 2 F-box domain TolA_bind_tri PF16331.5 KII90623.1 - 0.035 14.2 0.5 0.057 13.5 0.5 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation APG6_N PF17675.1 KII90623.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Sugar_tr PF00083.24 KII90624.1 - 7e-131 437.2 28.9 8.1e-131 437.0 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90624.1 - 8.4e-20 71.0 61.8 1.5e-18 66.9 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_B_thumb PF14791.6 KII90625.1 - 1.5e-16 60.3 1.0 8.4e-16 57.9 0.5 2.4 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KII90625.1 - 1.2e-15 57.7 0.0 7.2e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KII90625.1 - 9.5e-13 48.3 0.2 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KII90625.1 - 7.9e-11 41.6 0.4 1.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KII90625.1 - 0.00024 21.7 0.1 0.0096 16.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KII90625.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus NTP_transf_2 PF01909.23 KII90625.1 - 0.037 14.3 0.0 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF4332 PF14229.6 KII90625.1 - 0.099 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF3701 PF12482.8 KII90625.1 - 0.11 12.5 0.1 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 Phage integrase protein SNF5 PF04855.12 KII90626.1 - 7.5e-74 248.5 0.0 4.3e-73 246.0 0.0 1.9 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Q_salvage PF10343.9 KII90627.1 - 6.5e-77 258.9 0.0 7.7e-60 202.9 0.0 2.6 2 1 0 2 2 2 2 Potential Queuosine, Q, salvage protein family DUF963 PF06131.11 KII90630.1 - 0.19 11.2 2.2 0.56 9.7 2.2 1.9 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) AAA_16 PF13191.6 KII90631.1 - 0.00084 19.8 0.0 0.0035 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KII90631.1 - 0.011 15.5 0.6 0.033 13.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KII90631.1 - 0.015 14.5 0.1 0.078 12.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 KII90631.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KII90631.1 - 0.025 14.5 0.1 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KII90631.1 - 0.026 14.4 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KII90631.1 - 0.072 13.5 0.2 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII90631.1 - 0.096 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KII90631.1 - 0.12 12.4 0.1 0.99 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KII90631.1 - 0.17 11.6 0.2 0.35 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KII90632.1 - 0.012 15.5 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KII90632.1 - 0.027 13.7 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Myb_DNA-bind_3 PF12776.7 KII90635.1 - 2.8e-10 41.1 0.2 5.1e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CDC45 PF02724.14 KII90635.1 - 0.94 7.7 8.1 0.11 10.8 2.7 1.9 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 KII90635.1 - 6.8 7.1 9.8 1.2 9.5 3.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TraV PF09676.10 KII90635.1 - 9.6 7.2 16.1 0.7 10.9 5.8 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) WD40 PF00400.32 KII90636.1 - 2.5e-94 306.6 38.2 1.8e-10 41.2 0.1 10.1 10 0 0 10 10 10 9 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KII90636.1 - 4.1e-40 137.7 1.7 0.0026 16.8 0.0 9.9 1 1 9 10 10 10 9 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KII90636.1 - 6.4e-40 135.4 4.7 0.0035 17.6 0.0 9.5 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KII90636.1 - 8.3e-22 76.6 19.2 0.53 10.3 0.0 10.3 10 0 0 10 10 10 7 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KII90636.1 - 3.4e-10 40.1 1.6 0.1 12.4 0.1 4.6 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KII90636.1 - 7.9e-07 27.9 9.3 0.11 11.0 0.1 4.7 1 1 2 4 4 4 3 Cytochrome D1 heme domain PQQ PF01011.21 KII90636.1 - 1.7e-06 27.7 0.8 31 4.7 0.0 7.5 9 0 0 9 9 8 0 PQQ enzyme repeat zf-C2H2_12 PF18658.1 KII90636.1 - 2.9e-06 26.8 0.0 11 5.7 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger C2H2-type Nup160 PF11715.8 KII90636.1 - 3.1e-06 26.2 17.8 3.4 6.2 0.0 7.7 4 2 3 8 8 8 3 Nucleoporin Nup120/160 CN_hydrolase PF00795.22 KII90636.1 - 3.1e-05 23.4 7.9 14 4.9 0.0 7.6 4 2 6 10 10 10 0 Carbon-nitrogen hydrolase DUF5570 PF17731.1 KII90636.1 - 0.00045 20.3 12.4 20 5.3 0.1 7.1 3 3 4 7 7 7 0 Family of unknown function (DUF5570) EBP PF05241.12 KII90636.1 - 0.00069 19.1 4.9 3.7 7.0 0.4 5.5 2 2 2 4 4 4 1 Emopamil binding protein VMR2 PF17055.5 KII90636.1 - 0.00098 18.9 0.0 42 3.8 0.0 4.9 1 1 6 7 7 7 0 Viral matrix protein M2 Nbas_N PF15492.6 KII90636.1 - 0.0019 17.6 3.4 2 7.7 0.0 5.7 2 1 3 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Root_cap PF06830.11 KII90636.1 - 0.0042 17.2 0.1 1.1 9.5 0.0 3.8 4 0 0 4 4 4 1 Root cap potato_inhibit PF00280.18 KII90636.1 - 0.0066 17.1 5.9 7.7 7.3 0.1 5.8 2 2 6 8 8 7 0 Potato inhibitor I family DCX PF03607.17 KII90636.1 - 0.0069 16.5 0.1 1.9e+02 2.3 0.0 6.7 8 0 0 8 8 8 0 Doublecortin AcetylCoA_hyd_C PF13336.6 KII90636.1 - 0.019 14.9 0.1 34 4.3 0.0 4.2 5 1 1 6 6 5 0 Acetyl-CoA hydrolase/transferase C-terminal domain GCV_T_C PF08669.11 KII90636.1 - 0.042 13.8 20.9 14 5.7 0.1 8.0 8 1 1 9 9 9 0 Glycine cleavage T-protein C-terminal barrel domain PLD_C PF12357.8 KII90636.1 - 0.057 13.3 1.0 42 4.2 0.0 5.2 6 0 0 6 6 6 0 Phospholipase D C terminal DUF4454 PF14628.6 KII90636.1 - 0.061 13.1 0.4 6 6.6 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4454) TnpW PF14202.6 KII90636.1 - 0.075 12.9 0.3 68 3.4 0.1 4.6 4 1 0 4 4 3 0 Transposon-encoded protein TnpW DUF5597 PF18120.1 KII90636.1 - 0.081 13.0 0.0 73 3.5 0.0 3.8 1 1 4 5 5 5 0 Domain of unknown function (DUF5597) Proteasome_A_N PF10584.9 KII90636.1 - 1.4 8.6 37.9 25 4.7 0.2 9.5 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature GRIN_C PF15235.6 KII90636.1 - 1.7 8.9 12.6 33 4.7 0.1 4.4 3 1 1 4 4 4 0 G protein-regulated inducer of neurite outgrowth C-terminus MBOAT PF03062.19 KII90636.1 - 4.1 6.6 7.1 18 4.5 0.2 3.6 3 0 0 3 3 3 0 MBOAT, membrane-bound O-acyltransferase family eIF_4EBP PF05456.11 KII90640.1 - 0.034 14.1 0.3 0.081 12.9 0.3 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Sugar_tr PF00083.24 KII90641.1 - 2.4e-105 353.0 10.1 5.3e-105 351.9 10.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90641.1 - 8.3e-21 74.3 53.8 9.9e-15 54.3 27.7 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 KII90642.1 - 1.4e-62 210.9 48.1 3.8e-41 140.8 15.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KII90642.1 - 2.4e-37 128.5 0.0 3.6e-18 66.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KII90642.1 - 4.5e-28 97.0 12.8 6.9e-25 86.8 0.9 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KII90642.1 - 2.4e-16 60.1 0.2 6.9e-16 58.6 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KII90642.1 - 3.5e-08 34.0 0.0 0.00095 19.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KII90642.1 - 9.9e-07 28.8 0.1 6.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KII90642.1 - 1.8e-06 28.3 0.1 0.13 12.5 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KII90642.1 - 4.8e-06 26.3 0.1 0.00041 20.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII90642.1 - 0.00028 20.5 0.3 0.21 11.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII90642.1 - 0.00047 20.2 0.1 0.65 10.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KII90642.1 - 0.00049 20.1 0.1 0.15 12.0 0.1 2.9 3 0 0 3 3 2 1 NACHT domain AAA_18 PF13238.6 KII90642.1 - 0.00054 20.5 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KII90642.1 - 0.00069 19.8 0.1 0.41 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KII90642.1 - 0.0037 17.1 0.1 3.2 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KII90642.1 - 0.0062 17.0 0.2 0.95 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KII90642.1 - 0.0067 16.0 0.8 0.87 9.2 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KII90642.1 - 0.0087 16.5 0.0 7.5 7.0 0.1 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KII90642.1 - 0.0098 15.8 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 KII90642.1 - 0.012 15.9 0.1 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KII90642.1 - 0.018 14.7 0.3 1 9.1 0.5 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KII90642.1 - 0.04 13.2 0.1 6.9 5.9 0.2 2.3 2 0 0 2 2 2 0 Septin AAA_23 PF13476.6 KII90642.1 - 0.057 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KII90642.1 - 0.071 12.9 0.4 4.2 7.1 0.3 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 KII90642.1 - 0.11 12.8 0.0 8 6.8 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KII90642.1 - 0.13 12.5 0.1 3.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KII90642.1 - 0.13 12.2 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KII90642.1 - 0.15 12.0 0.1 0.59 10.1 0.1 2.0 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KII90642.1 - 0.15 11.3 0.1 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 KII90642.1 - 0.18 11.7 0.1 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mito_carr PF00153.27 KII90643.1 - 1.3e-53 178.9 4.0 1.5e-17 63.3 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KII90643.1 - 0.0042 16.3 2.5 0.11 11.7 0.2 2.9 2 1 1 3 3 3 2 Gammaproteobacterial serine protease Hist_deacetyl PF00850.19 KII90644.1 - 1.5e-52 179.0 0.1 2e-52 178.6 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain FoP_duplication PF13865.6 KII90645.1 - 1.3 9.7 0.0 1.3 9.7 0.0 4.0 5 0 0 5 5 5 0 C-terminal duplication domain of Friend of PRMT1 NAD_binding_4 PF07993.12 KII90646.1 - 8e-34 117.0 0.0 1.2e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII90646.1 - 3.1e-29 101.8 0.0 6.4e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII90646.1 - 1.1e-06 28.3 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII90646.1 - 4e-06 26.0 0.0 7.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII90646.1 - 1.5e-05 25.0 0.0 7.8e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KII90646.1 - 0.0011 18.9 0.0 0.0035 17.3 0.0 1.8 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 KII90646.1 - 0.026 14.9 0.1 0.092 13.1 0.1 2.0 1 1 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 KII90646.1 - 0.11 11.7 0.0 0.34 10.0 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GPI-anchored PF10342.9 KII90647.1 - 0.018 15.8 0.8 0.053 14.3 0.8 1.8 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ADH_zinc_N PF00107.26 KII90648.1 - 4.6e-12 46.0 0.0 8.6e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90648.1 - 3.4e-09 36.5 0.0 5.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII90648.1 - 0.017 16.1 0.0 0.029 15.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII90648.1 - 0.044 13.7 0.0 0.089 12.7 0.0 1.5 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase MFS_1 PF07690.16 KII90650.1 - 1.3e-46 159.2 49.6 7.8e-45 153.3 51.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII90650.1 - 2e-11 43.0 31.3 3.8e-11 42.1 31.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KII90650.1 - 2.3e-08 33.3 32.6 3.4e-08 32.8 16.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter VirB8 PF04335.13 KII90650.1 - 2 8.2 4.6 0.76 9.6 0.2 2.4 2 0 0 2 2 2 0 VirB8 protein adh_short_C2 PF13561.6 KII90651.1 - 8e-35 120.5 3.2 1.1e-34 120.0 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII90651.1 - 1.9e-21 76.4 0.5 2.4e-21 76.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Oxidored_nitro PF00148.19 KII90651.1 - 0.00053 18.8 0.0 0.00074 18.4 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase KR PF08659.10 KII90651.1 - 0.0033 17.4 1.1 0.005 16.8 1.1 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KII90651.1 - 0.008 16.3 1.6 0.02 15.0 1.4 1.7 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 KII90651.1 - 0.024 14.6 0.8 0.049 13.6 0.3 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KII90651.1 - 0.031 13.6 0.4 0.049 13.0 0.4 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KII90651.1 - 0.035 13.4 0.4 0.096 12.0 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KII90651.1 - 0.15 11.5 0.3 0.19 11.2 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sen15 PF09631.10 KII90652.1 - 3.4e-20 72.2 0.0 3.9e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein MFS_1 PF07690.16 KII90655.1 - 2.2e-21 76.2 52.1 1.7e-15 56.8 12.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII90655.1 - 1.6e-19 70.1 17.7 1.1e-18 67.4 1.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Ribosomal_S15 PF00312.22 KII90656.1 - 0.1 12.8 0.5 0.1 12.8 0.5 1.6 2 0 0 2 2 2 0 Ribosomal protein S15 DUF5579 PF17742.1 KII90656.1 - 2 7.9 4.8 1.1 8.8 2.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5579) Carb_kinase PF01256.17 KII90657.1 - 0.034 13.6 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase BTB PF00651.31 KII90658.1 - 3.8e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 KII90659.1 - 1.3e-26 92.3 0.2 0.00012 22.8 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90659.1 - 1.1e-09 38.4 0.0 0.22 11.9 0.0 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII90659.1 - 0.00074 18.3 0.1 0.04 12.6 0.0 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KII90659.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 KII90659.1 - 0.018 13.6 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KII90659.1 - 0.025 13.6 0.0 1.1 8.3 0.0 2.7 1 1 1 3 3 3 0 Coatomer WD associated region Ge1_WD40 PF16529.5 KII90659.1 - 0.031 13.2 0.3 1.7 7.5 0.1 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KII90659.1 - 0.074 12.4 0.0 1.4 8.2 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain DUF5046 PF16465.5 KII90659.1 - 0.096 12.1 0.0 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) DUF5310 PF17237.2 KII90660.1 - 2e-18 66.0 4.7 2.7e-18 65.5 4.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Vps55 PF04133.14 KII90660.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 zf-C3HC4_3 PF13920.6 KII90662.1 - 9.1e-09 35.1 10.1 1.3e-08 34.6 10.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII90662.1 - 8.9e-07 29.2 11.6 1.3e-06 28.6 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KII90662.1 - 1.6e-06 27.9 10.4 2.6e-06 27.3 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII90662.1 - 3.1e-05 23.7 13.0 4.7e-05 23.1 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII90662.1 - 0.00011 22.0 10.6 0.0032 17.3 11.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Spt4 PF06093.13 KII90662.1 - 0.00013 22.0 3.6 0.00023 21.2 0.1 2.3 1 1 1 2 2 2 1 Spt4/RpoE2 zinc finger zf-C3HC4 PF00097.25 KII90662.1 - 0.00028 20.7 10.9 0.00045 20.0 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII90662.1 - 0.0035 17.3 10.5 0.0059 16.6 10.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 KII90662.1 - 0.0059 16.4 10.8 0.02 14.7 10.9 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KII90662.1 - 0.13 12.5 12.7 0.24 11.6 12.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-WRNIP1_ubi PF18279.1 KII90662.1 - 0.23 12.2 5.5 9.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_6 PF14835.6 KII90662.1 - 0.4 10.6 5.0 0.59 10.0 5.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KII90662.1 - 0.88 9.4 9.0 0.28 11.0 5.6 1.9 1 1 1 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KII90662.1 - 1.8 8.8 8.7 3.2 8.0 8.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 DNA_ligase_ZBD PF03119.16 KII90662.1 - 2.5 8.2 0.0 2.5 8.2 0.0 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-H2C2_2 PF13465.6 KII90662.1 - 3.3 8.3 6.0 1.5 9.4 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Kin17_mid PF10357.9 KII90663.1 - 8.3e-50 167.9 0.4 1.3e-49 167.3 0.4 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KII90663.1 - 0.0012 19.2 4.8 0.0029 17.9 4.8 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII90663.1 - 0.014 15.7 3.6 0.036 14.4 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SET_assoc PF11767.8 KII90663.1 - 0.15 11.8 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated zf-C2H2_2 PF12756.7 KII90663.1 - 0.23 11.8 5.4 0.12 12.7 1.5 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2407_C PF13373.6 KII90664.1 - 1.2e-22 80.6 7.2 1.4e-20 73.9 7.2 3.0 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KII90664.1 - 3.1e-20 72.7 0.0 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KII90664.1 - 0.00041 20.0 0.0 0.00079 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family AI-2E_transport PF01594.16 KII90664.1 - 0.0034 16.6 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 AI-2E family transporter VIT1 PF01988.19 KII90664.1 - 0.059 13.2 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 VIT family IBN_N PF03810.19 KII90665.1 - 9.8e-09 35.0 0.0 2e-06 27.6 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KII90665.1 - 2.8e-05 24.4 3.2 0.027 14.9 0.1 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KII90665.1 - 0.00019 21.4 0.3 0.17 12.2 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KII90665.1 - 0.0011 19.0 0.3 0.29 11.2 0.3 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KII90665.1 - 0.0034 17.6 0.1 0.013 15.6 0.1 2.1 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Cse1 PF08506.10 KII90665.1 - 0.015 14.1 0.0 0.035 12.9 0.0 1.6 1 0 0 1 1 1 0 Cse1 Thiamine_BP PF01910.17 KII90665.1 - 0.025 14.5 0.3 0.098 12.6 0.1 2.2 2 0 0 2 2 2 0 Thiamine-binding protein HEAT_EZ PF13513.6 KII90665.1 - 0.12 13.0 1.2 19 5.9 0.2 4.4 3 1 0 3 3 3 0 HEAT-like repeat DUF3437 PF11919.8 KII90665.1 - 0.16 11.9 0.3 27 4.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Xpo1 PF08389.12 KII90665.1 - 0.55 10.3 3.6 1 9.4 0.0 3.3 3 1 0 3 3 3 0 Exportin 1-like protein PSS PF03034.15 KII90666.1 - 1.6e-114 382.3 14.6 2.4e-114 381.7 14.6 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.14 KII90666.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 PET Domain Zn_clus PF00172.18 KII90667.1 - 2.5e-08 33.9 7.3 5.6e-08 32.8 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TANGO2 PF05742.12 KII90668.1 - 1.3e-51 176.1 0.0 1.5e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Actin PF00022.19 KII90669.1 - 1.3e-78 264.4 0.0 1.3e-77 261.2 0.0 1.9 1 1 0 1 1 1 1 Actin DUF4449 PF14613.6 KII90672.1 - 3.6e-36 124.7 2.4 3.6e-36 124.7 2.4 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Apolipoprotein PF01442.18 KII90672.1 - 1.7 8.5 12.3 3.9 7.3 2.9 3.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF167 PF02594.16 KII90673.1 - 3.5e-09 36.6 35.9 1.3 9.2 0.3 9.3 2 2 7 9 9 9 7 Uncharacterised ACR, YggU family COG1872 DUF2939 PF11159.8 KII90673.1 - 0.0096 16.3 27.3 0.56 10.7 0.2 8.2 8 1 1 9 9 9 1 Protein of unknown function (DUF2939) CopC PF04234.12 KII90673.1 - 2.4 9.3 4.1 3.1e+02 2.5 0.0 4.9 1 1 6 7 7 7 0 CopC domain Nab1 PF04902.12 KII90673.1 - 9.4 6.6 15.6 2.2 8.6 0.5 4.5 4 3 2 6 6 6 0 Conserved region in Nab1 ADH_zinc_N PF00107.26 KII90674.1 - 2.6e-09 37.1 0.9 4.5e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90674.1 - 4.9e-09 36.0 0.6 4.1e-08 33.1 0.4 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII90674.1 - 0.00048 21.2 0.0 0.00087 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_M60_C PF18630.1 KII90674.1 - 0.067 13.3 0.1 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain DEAD PF00270.29 KII90675.1 - 4.9e-12 46.0 0.0 7.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII90675.1 - 2.4e-06 27.7 0.1 2.8e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC_6 PF15288.6 KII90675.1 - 5.3e-05 23.0 1.4 0.00015 21.5 1.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Helicase_C PF00271.31 KII90675.1 - 0.027 14.8 0.0 0.084 13.2 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 KII90678.1 - 3e-10 40.2 10.0 1.5e-06 28.4 2.6 3.3 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 KII90678.1 - 6.7e-08 32.4 3.3 0.00047 20.1 1.4 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-rbx1 PF12678.7 KII90678.1 - 2.9e-06 27.5 1.1 2.9e-06 27.5 1.1 3.1 3 1 0 3 3 2 2 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KII90678.1 - 1.8e-05 24.6 6.1 0.0025 17.7 0.6 2.8 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 KII90678.1 - 2.3e-05 24.2 9.2 4.9e-05 23.1 0.8 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KII90678.1 - 0.00012 22.1 3.3 0.003 17.6 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KII90678.1 - 0.00031 20.5 2.9 0.00031 20.5 2.9 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KII90678.1 - 0.00042 19.9 0.7 0.00042 19.9 0.7 2.7 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KII90678.1 - 0.0033 17.1 0.4 0.0033 17.1 0.4 3.5 4 0 0 4 4 3 2 RING-like zinc finger Prok-RING_4 PF14447.6 KII90678.1 - 0.0061 16.4 1.4 0.0061 16.4 1.4 3.1 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KII90678.1 - 0.0085 15.9 0.6 0.0085 15.9 0.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KII90678.1 - 0.039 14.1 1.1 1 9.6 0.2 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KII90678.1 - 0.11 12.6 0.9 0.27 11.4 0.9 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KII90678.1 - 4.1 7.4 7.8 6.1 6.8 0.7 2.7 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 KII90678.1 - 7.3 6.8 8.2 1.2 9.3 1.0 3.0 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KII90679.1 - 8.5e-63 212.2 0.0 1.5e-62 211.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90679.1 - 5.1e-38 130.8 0.0 6.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII90679.1 - 1.8e-10 40.6 0.0 3.7e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII90679.1 - 0.00024 20.0 0.1 0.00049 19.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KII90679.1 - 0.0015 17.9 0.3 0.029 13.7 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII90679.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII90679.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain F-box-like PF12937.7 KII90680.1 - 2.8e-05 23.9 3.5 6.4e-05 22.8 3.5 1.7 1 1 0 1 1 1 1 F-box-like HMw1_D2 PF18254.1 KII90680.1 - 0.012 15.9 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 0 HMW1 domain 2 Dynactin PF12455.8 KII90680.1 - 0.14 11.4 0.7 0.18 11.0 0.7 1.1 1 0 0 1 1 1 0 Dynein associated protein Ferritin_2 PF13668.6 KII90681.1 - 2.1e-43 147.8 0.1 3.5e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 KII90682.1 - 1e-43 148.8 5.9 1.6e-43 148.1 5.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KII90682.1 - 0.4 11.1 1.9 3.3 8.1 1.4 2.2 1 1 1 2 2 2 0 Rubrerythrin Cohesin_HEAT PF12765.7 KII90684.1 - 0.061 13.6 7.7 85 3.6 0.3 6.1 3 2 2 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DUF3446 PF11928.8 KII90686.1 - 0.056 13.8 1.3 0.1 12.9 1.3 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain CxC2 PF18803.1 KII90687.1 - 1.4e-42 144.2 0.0 2.3e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII90687.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KII90687.1 - 0.0066 16.6 4.7 0.0066 16.6 4.7 2.1 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KII90687.1 - 0.016 15.0 4.2 0.016 15.0 4.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) KDZ PF18758.1 KII90688.1 - 8.6e-13 48.4 0.0 9.5e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase adh_short_C2 PF13561.6 KII90691.1 - 7.1e-29 101.0 0.0 1.3e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KDZ PF18758.1 KII90691.1 - 7.6e-29 100.9 0.2 7.6e-29 100.9 0.2 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase adh_short PF00106.25 KII90691.1 - 2e-11 43.7 0.0 3.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GFO_IDH_MocA PF01408.22 KII90692.1 - 7.1e-16 59.1 0.0 1.5e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KII90692.1 - 0.054 14.1 0.0 0.22 12.1 0.0 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 KII90692.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain F-box-like PF12937.7 KII90693.1 - 4.5e-08 32.9 1.6 1e-07 31.7 1.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII90693.1 - 0.0021 17.9 0.1 0.006 16.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain APG6_N PF17675.1 KII90693.1 - 0.19 12.3 0.0 0.29 11.7 0.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region LRR_9 PF14580.6 KII90693.1 - 0.22 11.0 0.1 1.7 8.2 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat GFO_IDH_MocA PF01408.22 KII90694.1 - 2.6e-16 60.5 0.1 5.3e-16 59.5 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII90694.1 - 3.4e-05 23.8 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KII90694.1 - 0.044 14.4 0.9 0.11 13.1 0.0 2.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Acetyltransf_3 PF13302.7 KII90697.1 - 2.9e-19 70.1 0.1 5e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII90697.1 - 2.2e-09 37.6 0.0 3.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KII90697.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII90697.1 - 0.0012 19.2 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII90697.1 - 0.031 14.2 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII90697.1 - 0.052 13.7 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NmrA PF05368.13 KII90698.1 - 4.7e-50 170.3 0.0 5.6e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII90698.1 - 5.2e-20 72.1 0.0 7.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KII90698.1 - 2.7e-07 29.9 0.0 2e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII90698.1 - 0.00012 21.7 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KII90698.1 - 0.031 14.6 0.1 0.092 13.0 0.0 1.8 3 0 0 3 3 3 0 TrkA-N domain DUF3454 PF11936.8 KII90699.1 - 0.015 15.7 2.7 0.015 15.7 2.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3454) Abhydrolase_1 PF00561.20 KII90700.1 - 2.7e-21 76.4 0.1 1.3e-19 70.9 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KII90700.1 - 1.1e-20 73.7 0.6 4.5e-20 71.7 0.1 2.3 3 0 0 3 3 3 1 TAP-like protein WD40 PF00400.32 KII90704.1 - 0.00079 20.2 0.3 0.018 15.9 0.2 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Helicase_C PF00271.31 KII90705.1 - 6.8e-10 39.3 0.0 1.6e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90705.1 - 5.7e-06 26.2 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 KII90705.1 - 0.089 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.7 KII90709.1 - 8.3e-05 22.4 0.9 8.3e-05 22.4 0.9 2.4 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 KII90710.1 - 1.7e-22 79.9 63.1 1.9e-19 69.8 41.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII90710.1 - 0.00027 19.9 8.2 0.00027 19.9 8.2 3.7 1 1 2 4 4 4 3 Sugar (and other) transporter PBP1_TM PF14812.6 KII90711.1 - 0.97 9.9 10.1 0.88 10.0 2.9 3.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAF PF11250.8 KII90711.1 - 2 8.7 7.3 7.2 6.9 0.0 3.6 3 0 0 3 3 3 0 Fantastic Four meristem regulator SPRY PF00622.28 KII90714.1 - 1.8e-11 44.2 0.0 2.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain TFIIS_C PF01096.18 KII90715.1 - 3.7e-15 55.5 4.4 3.7e-15 55.5 4.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KII90715.1 - 4.9e-09 35.9 0.7 4.9e-09 35.9 0.7 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DUF3716 PF12511.8 KII90715.1 - 0.023 14.7 10.3 0.063 13.3 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) PhnA_Zn_Ribbon PF08274.12 KII90715.1 - 1.4 8.9 13.9 5.6 7.0 0.1 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon AMP-binding PF00501.28 KII90716.1 - 6.7e-72 242.4 0.0 8.4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII90716.1 - 5e-06 27.4 0.0 1.1e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KII90717.1 - 2.1e-72 244.1 0.0 2.4e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII90717.1 - 7e-07 30.1 0.0 1.3e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM PF10378.9 KII90717.1 - 0.087 12.6 1.5 6.1 6.7 0.2 2.5 2 0 0 2 2 2 0 Putative RRM domain zf-MYND PF01753.18 KII90718.1 - 2.5e-06 27.4 11.1 4.8e-06 26.6 11.1 1.5 1 0 0 1 1 1 1 MYND finger RhoGAP PF00620.27 KII90719.1 - 2.4e-30 105.4 0.0 3.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 KII90719.1 - 8.4e-30 103.7 0.1 1.6e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 KII90719.1 - 0.00021 21.1 0.1 0.00084 19.1 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain Glyco_hydro_88 PF07470.13 KII90720.1 - 2.3e-16 59.8 0.7 3.7e-16 59.1 0.7 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4387 PF14330.6 KII90721.1 - 1.7e-36 124.8 0.0 4.7e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KII90721.1 - 1.2e-13 50.6 0.1 2.1e-12 46.5 0.0 2.4 2 1 0 2 2 2 1 Acyclic terpene utilisation family protein AtuA bZIP_1 PF00170.21 KII90722.1 - 1.1e-07 31.8 7.7 2e-07 31.0 7.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII90722.1 - 2.4e-07 30.7 8.9 4.3e-07 29.9 8.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KII90722.1 - 0.0042 17.6 2.3 0.008 16.7 2.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GDA1_CD39 PF01150.17 KII90723.1 - 3.2e-94 316.0 0.0 4.3e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KII90723.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family adh_short_C2 PF13561.6 KII90724.1 - 8.7e-57 192.4 0.9 1.2e-56 191.9 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII90724.1 - 2.4e-52 177.3 0.2 3e-52 176.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII90724.1 - 5e-12 46.1 0.9 7e-12 45.6 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII90724.1 - 0.016 14.6 0.2 0.048 13.1 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 KII90724.1 - 0.066 13.8 0.5 2.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Mito_carr PF00153.27 KII90725.1 - 2.6e-66 219.6 7.6 3e-24 84.8 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferritin_2 PF13668.6 KII90726.1 - 3e-45 153.8 1.4 4.8e-45 153.1 1.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KII90726.1 - 0.098 13.4 1.1 0.37 11.5 1.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4439) ADH_zinc_N PF00107.26 KII90727.1 - 2.5e-26 92.2 0.1 4.6e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII90727.1 - 8.7e-19 68.9 0.0 1.8e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90727.1 - 2.1e-06 27.6 0.0 6.2e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-RNPHF PF08080.12 KII90727.1 - 0.00012 21.9 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 RNPHF zinc finger ELFV_dehydrog PF00208.21 KII90727.1 - 0.033 13.9 0.1 0.048 13.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ferritin_2 PF13668.6 KII90728.1 - 1.8e-45 154.5 1.5 3.1e-45 153.7 1.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KII90728.1 - 0.088 13.5 1.4 0.32 11.7 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4439) DAO PF01266.24 KII90729.1 - 7.8e-53 180.3 0.1 1.1e-52 179.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KII90729.1 - 6e-47 158.6 0.0 1.2e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 KII90729.1 - 1.2e-05 24.8 0.4 0.00055 19.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII90729.1 - 5.4e-05 22.4 7.0 5.4e-05 22.4 7.0 2.4 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KII90729.1 - 0.0029 16.9 1.9 0.011 15.0 1.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII90729.1 - 0.011 15.9 0.5 0.057 13.6 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KII90729.1 - 0.015 14.4 0.3 0.32 10.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KII90729.1 - 0.023 13.9 0.8 0.21 10.8 0.8 2.1 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KII90729.1 - 0.032 13.5 0.1 0.067 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KII90729.1 - 0.033 14.8 3.4 0.13 12.9 0.5 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII90729.1 - 0.033 12.9 0.9 0.053 12.2 0.9 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KII90729.1 - 0.05 12.9 0.1 0.093 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 KII90730.1 - 9.8e-85 284.7 0.0 1.3e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII90730.1 - 1.2e-15 58.3 0.1 4.1e-15 56.5 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4271 PF14093.6 KII90732.1 - 1.1 9.1 20.8 0.069 13.1 14.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) HTH_16 PF12645.7 KII90734.1 - 0.0046 17.0 0.5 23 5.2 0.0 4.4 4 0 0 4 4 4 1 Helix-turn-helix domain Peptidase_C50 PF03568.17 KII90734.1 - 0.027 13.6 0.5 3.1 6.8 0.1 2.7 1 1 2 3 3 3 0 Peptidase family C50 RsbRD_N PF14361.6 KII90734.1 - 0.1 13.3 22.8 17 6.1 0.3 5.9 6 0 0 6 6 6 0 RsbT co-antagonist protein rsbRD N-terminal domain RNase_3_N PF18497.1 KII90734.1 - 0.46 10.7 0.0 0.46 10.7 0.0 2.9 4 0 0 4 4 4 0 Ribonuclease III N-terminal domain Phage_CII PF05269.11 KII90734.1 - 1.2 9.4 16.6 31 4.9 0.2 5.5 4 2 0 5 5 5 0 Bacteriophage CII protein PEP-utilizers PF00391.23 KII90734.1 - 1.3 8.8 5.0 13 5.6 0.1 4.1 5 0 0 5 5 5 0 PEP-utilising enzyme, mobile domain DUF834 PF05754.14 KII90734.1 - 5.4 7.1 8.4 23 5.1 0.5 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF834) DUF3783 PF12646.7 KII90737.1 - 4.5e-05 23.3 0.0 19 5.3 0.0 6.2 7 1 1 8 8 8 2 Domain of unknown function (DUF3783) Cadherin_pro PF08758.11 KII90737.1 - 0.019 15.1 4.5 72 3.7 0.0 6.3 6 2 1 7 7 7 0 Cadherin prodomain like DUF4272 PF14094.6 KII90737.1 - 0.044 13.0 4.6 46 3.2 0.0 5.3 3 2 3 6 6 6 0 Domain of unknown function (DUF4272) E1-E2_ATPase PF00122.20 KII90739.1 - 0.68 9.4 2.2 0.59 9.6 0.8 1.6 2 0 0 2 2 2 0 E1-E2 ATPase AF-4 PF05110.13 KII90740.1 - 1.1 7.2 8.7 1.5 6.8 8.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein COesterase PF00135.28 KII90741.1 - 1.9e-92 310.8 0.0 3.9e-92 309.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII90741.1 - 9.1e-07 28.9 0.2 4.6e-06 26.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1593 PF07632.11 KII90742.1 - 2e-95 319.1 0.0 2.9e-95 318.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 KII90742.1 - 0.02 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 REJ domain FMN_red PF03358.15 KII90743.1 - 2.8e-06 27.1 0.0 3.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KII90743.1 - 0.0026 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Pkinase PF00069.25 KII90744.1 - 2.1e-50 171.6 0.0 2.5e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90744.1 - 1.8e-24 86.4 0.1 1.7e-23 83.3 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KII90744.1 - 0.0033 17.1 0.2 0.0059 16.2 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KII90744.1 - 0.0055 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII90744.1 - 0.0058 16.0 0.1 0.0094 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII90744.1 - 0.066 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KII90744.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AhpC-TSA PF00578.21 KII90745.1 - 2.8e-28 98.3 0.0 3.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII90745.1 - 5.4e-17 61.9 0.0 7.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Linker_histone PF00538.19 KII90746.1 - 3.9e-08 33.5 0.0 6.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family EBV-NA3 PF05009.12 KII90746.1 - 4.4 6.7 5.9 9.1 5.7 3.2 2.5 3 0 0 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Lipase_3 PF01764.25 KII90747.1 - 2.1e-22 79.5 0.0 2.8e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII90747.1 - 0.00078 20.1 0.2 0.0041 17.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KII90747.1 - 0.0012 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KII90747.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KII90747.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 KII90747.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Aldo_ket_red PF00248.21 KII90748.1 - 6.5e-60 202.8 0.0 1.5e-59 201.6 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII90749.1 - 2e-65 220.9 0.1 2.3e-65 220.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mitoc_mL59 PF18126.1 KII90749.1 - 0.05 13.9 1.6 0.096 13.0 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 EHN PF06441.12 KII90750.1 - 1.3e-34 118.8 0.8 2.1e-33 114.9 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII90750.1 - 6.5e-08 32.5 0.0 7.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII90750.1 - 0.006 17.2 5.9 0.023 15.3 5.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 KII90751.1 - 3.7e-70 237.0 0.0 4.3e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DEC1 PF15859.5 KII90751.1 - 0.067 13.2 0.1 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Deleted in esophageal cancer 1 family TetR_C_25 PF17933.1 KII90751.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NmrA PF05368.13 KII90752.1 - 1.4e-19 70.6 0.0 1.9e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Glu_dehyd_C PF16912.5 KII90752.1 - 0.00013 21.5 0.2 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus KR PF08659.10 KII90752.1 - 0.035 14.0 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 KII90752.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain rve PF00665.26 KII90753.1 - 4.6e-05 23.6 0.0 6.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Se-cys_synth_N PF12390.8 KII90756.1 - 0.04 14.1 0.6 0.82 9.9 0.2 2.2 2 0 0 2 2 2 0 Selenocysteine synthase N terminal zf-CCHC PF00098.23 KII90758.1 - 0.079 13.1 6.2 0.14 12.3 6.2 1.4 1 0 0 1 1 1 0 Zinc knuckle PX PF00787.24 KII90759.1 - 9.7e-14 51.3 0.1 8.2e-12 45.1 0.1 3.0 2 0 0 2 2 2 1 PX domain PLDc PF00614.22 KII90759.1 - 1.2e-13 50.6 0.2 5.4e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KII90759.1 - 3.1e-13 49.8 0.0 5e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PH PF00169.29 KII90759.1 - 0.042 14.4 1.0 4.8 7.7 0.1 2.6 2 0 0 2 2 2 0 PH domain PH_11 PF15413.6 KII90759.1 - 0.057 13.8 1.0 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Dabb PF07876.12 KII90760.1 - 1.6e-19 70.3 0.0 1.8e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.12 KII90761.1 - 1.5e-18 67.2 0.0 1.7e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain E1_dh PF00676.20 KII90763.1 - 2.7e-83 279.4 0.0 3.2e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4448 PF14610.6 KII90764.1 - 0.059 13.1 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Podoplanin PF05808.11 KII90764.1 - 0.12 12.5 1.5 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Podoplanin LapA_dom PF06305.11 KII90764.1 - 2.1 8.2 3.9 0.47 10.3 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain peroxidase PF00141.23 KII90765.1 - 5e-29 101.6 0.0 7.5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KII90765.1 - 1.5e-28 98.5 1.2 3.2e-28 97.5 1.2 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region vATP-synt_AC39 PF01992.16 KII90766.1 - 3e-116 388.6 0.3 3.4e-116 388.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit MFS_1 PF07690.16 KII90767.1 - 2.4e-28 99.1 31.4 2.4e-28 99.1 31.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KII90767.1 - 0.0087 15.9 1.8 0.14 11.9 0.2 2.5 2 1 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2614 PF11023.8 KII90767.1 - 0.015 15.4 1.4 0.36 10.9 0.0 2.9 3 0 0 3 3 3 0 Zinc-ribbon containing domain DLH PF01738.18 KII90768.1 - 3.2e-21 75.9 0.1 7.4e-21 74.7 0.1 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KII90768.1 - 0.093 12.4 0.2 0.23 11.1 0.1 1.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peroxidase_ext PF11895.8 KII90769.1 - 4.2e-31 106.7 1.1 8.5e-31 105.7 1.1 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KII90769.1 - 1.2e-28 100.4 0.0 1.7e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase zf-Tim10_DDP PF02953.15 KII90770.1 - 3.6e-20 71.4 7.0 4.9e-20 71.0 7.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger OHCU_decarbox PF09349.10 KII90770.1 - 0.053 14.0 0.0 0.067 13.7 0.0 1.1 1 0 0 1 1 1 0 OHCU decarboxylase DAHP_synth_1 PF00793.20 KII90771.1 - 1.6e-95 319.1 0.0 2e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Scm3 PF10384.9 KII90772.1 - 5.4e-12 45.3 0.5 1.3e-11 44.1 0.5 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 3Beta_HSD PF01073.19 KII90773.1 - 5.5e-10 38.7 0.0 1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII90773.1 - 7.9e-08 32.1 0.0 3.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII90773.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII90773.1 - 0.00044 19.5 0.0 0.0067 15.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KII90773.1 - 0.041 13.4 0.1 0.095 12.2 0.2 1.5 2 0 0 2 2 2 0 NmrA-like family Mit_KHE1 PF10173.9 KII90774.1 - 4.2e-52 177.0 0.0 5.3e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Mit_KHE1 PF10173.9 KII90775.1 - 1.3e-27 97.1 3.9 2.1e-27 96.5 3.9 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Plavaka PF18759.1 KII90776.1 - 5.3e-29 101.5 0.1 9.4e-29 100.6 0.1 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2 PF00096.26 KII90776.1 - 0.003 17.9 0.4 0.016 15.6 0.4 2.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type Ten1 PF12658.7 KII90776.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Telomere capping, CST complex subunit Spem1 PF15670.5 KII90777.1 - 0.71 9.4 3.3 1.1 8.8 3.3 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Mit_KHE1 PF10173.9 KII90778.1 - 4.9e-06 26.8 0.0 6.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Zip PF02535.22 KII90779.1 - 8.6e-29 100.8 7.6 1.5e-28 100.0 7.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1772 PF08592.11 KII90779.1 - 0.19 12.0 2.2 2 8.7 2.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) mRNA_triPase PF02940.15 KII90780.1 - 5.7e-55 186.4 0.0 6.7e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain F-box-like PF12937.7 KII90781.1 - 1.1e-07 31.6 2.7 2.2e-07 30.7 2.7 1.5 1 1 0 1 1 1 1 F-box-like MIP PF00230.20 KII90783.1 - 8.6e-54 182.6 2.7 1e-53 182.4 2.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein GCFC PF07842.12 KII90784.1 - 0.16 11.6 0.0 0.77 9.3 0.0 2.0 1 1 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Rad60-SLD PF11976.8 KII90785.1 - 1.6e-09 37.4 0.0 0.0076 16.1 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like PH PF00169.29 KII90787.1 - 8.8e-05 23.0 0.6 0.0002 21.8 0.6 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KII90787.1 - 0.23 11.9 5.4 0.97 9.9 1.9 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain POB3_N PF17292.2 KII90788.1 - 1.3e-33 115.3 0.4 2.7e-29 101.4 0.1 2.7 2 1 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KII90788.1 - 7e-26 89.9 0.6 1.6e-25 88.8 0.0 2.0 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KII90788.1 - 1.7e-21 76.4 0.1 9.7e-21 74.0 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Adeno_shaft PF00608.17 KII90792.1 - 2.3e-05 24.0 2.1 7.3 6.6 0.1 6.0 3 2 2 5 5 5 2 Adenoviral fibre protein (repeat/shaft region) HBS1_N PF08938.10 KII90792.1 - 1 9.7 3.1 11 6.5 0.1 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Cauli_VI PF01693.16 KII90793.1 - 4.5e-15 55.7 2.6 3.8e-09 36.7 0.0 3.2 3 0 0 3 3 3 3 Caulimovirus viroplasmin OrfB_IS605 PF01385.19 KII90794.1 - 0.045 14.0 0.5 6 7.1 0.1 2.1 2 0 0 2 2 2 0 Probable transposase KDZ PF18758.1 KII90795.1 - 5.7e-51 173.3 0.0 9.8e-51 172.5 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII90795.1 - 3.3e-39 133.3 0.0 8.6e-39 132.0 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII90795.1 - 2.5e-05 24.3 0.0 6.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases zf-B_box PF00643.24 KII90795.1 - 0.016 15.4 4.7 0.016 15.4 4.7 1.9 2 0 0 2 2 2 0 B-box zinc finger CxC3 PF18804.1 KII90795.1 - 0.27 11.1 2.4 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases CH PF00307.31 KII90796.1 - 2.2e-48 163.0 0.0 6.1e-26 90.7 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Cofilin_ADF PF00241.20 KII90796.1 - 2.6e-39 133.7 1.6 5.2e-39 132.8 0.3 2.2 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein EFhand_Ca_insen PF08726.10 KII90796.1 - 4.9e-16 58.6 0.3 2.1e-14 53.4 0.0 3.4 3 1 1 4 4 4 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KII90796.1 - 5.5e-13 48.6 0.1 3.5e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Seryl_tRNA_N PF02403.22 KII90796.1 - 0.0004 20.6 0.4 0.0015 18.7 0.4 2.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KII90796.1 - 0.013 14.4 5.2 0.026 13.4 5.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein EF-hand_8 PF13833.6 KII90796.1 - 0.019 14.8 0.3 12 5.9 0.0 4.0 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_6 PF13405.6 KII90796.1 - 0.023 14.6 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 1 0 EF-hand domain Spectrin PF00435.21 KII90796.1 - 0.058 13.9 7.4 0.13 12.7 2.1 3.2 2 1 0 2 2 2 0 Spectrin repeat SF3A3 PF16837.5 KII90796.1 - 0.088 13.3 0.0 0.8 10.3 0.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF2884 PF11101.8 KII90796.1 - 0.09 12.3 4.0 0.047 13.2 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) EF-hand_14 PF17959.1 KII90796.1 - 0.11 12.8 1.4 18 5.8 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain COG2 PF06148.11 KII90796.1 - 0.17 11.9 3.7 0.48 10.5 1.2 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mce4_CUP1 PF11887.8 KII90796.1 - 0.23 10.9 2.6 2.1 7.7 0.2 2.4 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TolA_bind_tri PF16331.5 KII90796.1 - 0.24 11.5 2.5 0.74 9.9 2.5 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation Apolipoprotein PF01442.18 KII90796.1 - 0.39 10.6 9.5 0.043 13.7 4.6 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 KII90796.1 - 0.39 10.7 3.6 0.99 9.4 3.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 KII90796.1 - 0.47 11.0 2.4 2.4 8.7 2.4 2.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 KII90796.1 - 2 8.5 4.7 15 5.6 4.5 2.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 KII90796.1 - 2.2 8.5 6.7 2.7 8.2 1.5 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Porin_3 PF01459.22 KII90797.1 - 1.6e-72 244.2 0.2 1.8e-72 244.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin SpoIIP PF07454.11 KII90797.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RPAP3_C PF13877.6 KII90798.1 - 4e-17 62.5 0.1 7e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KII90798.1 - 8.3e-16 57.1 1.2 1.2e-05 24.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII90798.1 - 2.1e-11 43.0 2.9 0.0058 16.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII90798.1 - 5e-10 39.9 3.8 5e-06 27.1 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII90798.1 - 8.7e-10 38.1 1.5 0.00035 20.2 0.2 3.0 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 KII90798.1 - 3.7e-07 30.5 1.8 2.3e-05 24.8 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII90798.1 - 3.9e-06 26.9 0.2 0.03 14.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KII90798.1 - 8.4e-06 25.8 0.6 0.088 12.9 0.1 2.4 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KII90798.1 - 2.5e-05 24.1 0.5 0.46 10.8 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII90798.1 - 0.00013 21.8 0.9 0.14 12.3 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII90798.1 - 0.00022 21.8 2.3 4.6 8.3 0.1 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII90798.1 - 0.00023 21.4 2.4 0.013 15.8 1.3 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII90798.1 - 0.0028 17.8 1.0 0.15 12.3 0.2 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KII90798.1 - 0.058 13.8 0.4 0.15 12.5 0.4 1.7 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 KII90798.1 - 0.064 12.5 1.1 0.82 8.8 0.2 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KII90798.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_10 PF13374.6 KII90798.1 - 0.14 12.0 1.9 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KII90798.1 - 0.16 12.4 0.2 6 7.5 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Use1 PF09753.9 KII90798.1 - 0.22 11.2 1.7 4.7 6.9 0.0 2.2 1 1 0 2 2 2 0 Membrane fusion protein Use1 MIT PF04212.18 KII90798.1 - 0.35 11.0 7.3 0.73 9.9 0.2 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KII90798.1 - 0.58 10.9 2.1 86 4.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 KII90799.1 - 7.5e-26 91.1 0.0 1.3e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KII90799.1 - 2.1e-18 66.3 21.8 1.2e-05 25.9 0.1 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat M20_dimer PF07687.14 KII90799.1 - 6.7e-12 45.3 0.0 1.7e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Nup160 PF11715.8 KII90799.1 - 4.5e-05 22.3 5.1 0.0018 17.0 1.6 2.9 2 2 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII90799.1 - 0.0099 16.2 0.1 8.9 6.7 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Prefoldin PF02996.17 KII90801.1 - 0.025 14.5 0.0 0.026 14.4 0.0 1.0 1 0 0 1 1 1 0 Prefoldin subunit CK2S PF15011.6 KII90801.1 - 0.14 12.1 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Casein Kinase 2 substrate F-box-like PF12937.7 KII90802.1 - 8.1e-10 38.4 0.9 7.2e-09 35.4 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII90802.1 - 0.026 14.4 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 F-box domain Mon1 PF03164.14 KII90803.1 - 9.3e-118 393.8 0.0 1.1e-117 393.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-MYND PF01753.18 KII90804.1 - 4.5e-09 36.3 14.5 6.9e-09 35.7 14.5 1.3 1 0 0 1 1 1 1 MYND finger zf-CCCH_2 PF14608.6 KII90804.1 - 0.0088 16.5 1.0 0.03 14.8 1.0 1.9 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-C6H2 PF15801.5 KII90804.1 - 0.2 12.0 15.9 0.43 10.9 15.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MFS_1 PF07690.16 KII90805.1 - 1e-18 67.4 44.4 2.3e-18 66.2 44.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRAM_LAG1_CLN8 PF03798.16 KII90806.1 - 7.3e-33 114.0 28.3 7.3e-33 114.0 28.3 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KII90806.1 - 1.8e-18 65.9 0.2 1.8e-18 65.9 0.2 2.4 2 0 0 2 2 2 1 TRAM1-like protein DUF2561 PF10812.8 KII90807.1 - 0.036 14.1 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF3180 PF11377.8 KII90807.1 - 0.19 11.8 3.3 0.97 9.6 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) DUF2301 PF10063.9 KII90807.1 - 4 7.9 7.1 2.6 8.5 4.8 1.7 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Glyco_hydro_43 PF04616.14 KII90808.1 - 3.4e-45 154.6 3.8 4.1e-45 154.3 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Flagellin_D3 PF08884.11 KII90808.1 - 0.4 11.1 3.7 14 6.2 0.0 2.7 3 0 0 3 3 3 0 Flagellin D3 domain ADH_N PF08240.12 KII90809.1 - 1.2e-26 92.7 0.4 2.1e-26 91.9 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII90809.1 - 2.8e-06 27.3 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KII90809.1 - 0.15 12.0 0.4 0.29 11.1 0.4 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated NAD_binding_9 PF13454.6 KII90809.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding IGR PF09597.10 KII90810.1 - 4.1e-20 71.6 0.0 6.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif BTB PF00651.31 KII90811.1 - 6.8e-06 26.3 0.0 1.7e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2 PF00096.26 KII90812.1 - 6.4e-05 23.2 5.3 0.062 13.8 0.0 2.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII90812.1 - 0.00064 20.3 2.0 0.9 10.6 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KII90812.1 - 0.021 14.6 10.6 0.11 12.2 7.1 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KII90812.1 - 1.6 9.3 0.0 1.6 9.3 0.0 3.0 4 0 0 4 4 4 0 Zinc-finger double domain FHA PF00498.26 KII90813.1 - 8.5e-15 54.9 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KII90813.1 - 2.5e-05 24.5 0.0 0.00076 19.8 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4551 PF15087.6 KII90813.1 - 3.9 6.2 5.3 4.5 6.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Herpes_U5 PF05999.11 KII90815.1 - 0.032 13.0 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family FGFR3_TM PF18123.1 KII90815.1 - 1.1 8.8 5.9 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 Fibroblast growth factor receptor 3 transmembrane domain Glyco_hydro_16 PF00722.21 KII90816.1 - 0.00016 21.2 0.1 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 GIT_SHD PF08518.11 KII90818.1 - 1.9e-17 62.6 0.2 1.6e-10 40.4 0.2 2.2 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Auts2 PF15336.6 KII90818.1 - 0.047 13.8 0.4 0.078 13.1 0.4 1.4 1 1 0 1 1 1 0 Autism susceptibility gene 2 protein DEAD PF00270.29 KII90823.1 - 3.1e-14 53.1 0.2 7e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII90823.1 - 8e-10 39.1 0.0 2.6e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII90823.1 - 1.6e-08 34.8 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.19 KII90823.1 - 0.69 10.5 11.5 3 8.5 9.7 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_zinc_N PF00107.26 KII90824.1 - 2.4e-29 101.9 0.2 3.8e-29 101.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII90824.1 - 1.5e-15 58.4 0.0 3.4e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII90824.1 - 5.1e-09 36.0 0.3 1.3e-07 31.4 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.7 KII90826.1 - 9.2e-08 33.0 2.8 1.2e-07 32.6 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII90826.1 - 2.3e-06 27.0 0.5 3.9e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII90826.1 - 1.8e-05 24.4 0.3 0.00019 21.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1749 PF08538.10 KII90826.1 - 0.00072 18.7 0.0 0.00099 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 KII90826.1 - 0.0041 16.8 0.3 0.024 14.3 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KII90826.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_L1 PF00687.21 KII90828.1 - 4e-53 180.2 0.1 5.2e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Peptidase_M64 PF09471.10 KII90829.1 - 1.8e-29 103.0 0.0 2.9e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 Chromo_2 PF18704.1 KII90829.1 - 0.2 12.0 0.2 0.75 10.1 0.1 1.9 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 Pkinase PF00069.25 KII90830.1 - 1.8e-72 243.9 0.0 3.2e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90830.1 - 1.5e-51 175.2 0.0 2.7e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RICTOR_N PF14664.6 KII90830.1 - 0.002 17.2 8.5 0.27 10.2 0.6 3.1 1 1 2 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term Pkinase_fungal PF17667.1 KII90830.1 - 0.0023 16.8 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII90830.1 - 0.0077 15.6 0.0 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF3385 PF11865.8 KII90830.1 - 0.014 15.3 0.3 3.9 7.4 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Ric8 PF10165.9 KII90830.1 - 0.1 11.6 1.4 1.2 8.1 0.1 2.6 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Ribosomal_L5_C PF00673.21 KII90831.1 - 3.3e-26 91.3 0.0 4.8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Zn_clus PF00172.18 KII90833.1 - 6.2e-08 32.6 10.5 1.5e-07 31.4 10.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII90833.1 - 0.021 13.8 3.5 0.08 12.0 1.1 2.3 1 1 1 2 2 2 0 Fungal specific transcription factor domain Dynamin_N PF00350.23 KII90834.1 - 1.3e-18 67.7 0.4 5.5e-18 65.6 0.0 2.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KII90834.1 - 2e-13 50.4 0.1 1.1e-12 48.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII90834.1 - 4.3e-09 36.2 0.2 2.8e-08 33.5 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII90834.1 - 0.0001 22.2 0.9 0.071 13.0 0.3 2.7 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 KII90834.1 - 0.00071 19.2 0.1 0.13 11.8 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KII90834.1 - 0.0076 16.5 0.0 1.2 9.4 0.0 3.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KII90834.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 KII90834.1 - 0.025 14.0 0.6 10 5.5 0.2 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_29 PF13555.6 KII90834.1 - 0.039 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KII90834.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KII90834.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin PPTA PF01239.22 KII90835.1 - 6.5e-12 44.8 10.6 5.3e-08 32.3 0.2 5.1 6 0 0 6 6 6 2 Protein prenyltransferase alpha subunit repeat APH_6_hur PF04655.14 KII90835.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Aminotran_5 PF00266.19 KII90839.1 - 5.2e-11 42.1 0.0 6e-10 38.6 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KII90839.1 - 1.7e-05 24.3 0.3 0.0031 16.9 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KII90839.1 - 2.3e-05 23.8 0.0 3.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3767 PF12597.8 KII90840.1 - 2.4e-16 59.4 0.3 3e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Glyco_hydro_18 PF00704.28 KII90841.1 - 1.4e-60 205.6 1.5 1.9e-60 205.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNA_pol_E_B PF04042.16 KII90842.1 - 1.4e-29 103.0 0.2 1.8e-29 102.6 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KII90842.1 - 2.9e-29 102.7 0.0 8.8e-15 55.3 0.2 2.2 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal ORC2 PF04084.14 KII90843.1 - 2e-90 303.1 0.0 2.3e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MqsA_antitoxin PF15731.5 KII90843.1 - 0.19 11.8 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA MIP PF00230.20 KII90844.1 - 9.1e-54 182.6 7.5 1.1e-53 182.3 7.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein TraS PF10624.9 KII90844.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS EamA PF00892.20 KII90844.1 - 1.9 8.7 8.9 0.22 11.7 0.7 2.9 3 0 0 3 3 3 0 EamA-like transporter family NMO PF03060.15 KII90845.1 - 1.7e-53 182.2 0.3 8.7e-53 179.8 0.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KII90845.1 - 2.3e-10 40.0 0.6 7.8e-05 21.8 0.4 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KII90845.1 - 3.6e-05 23.0 1.0 5.3e-05 22.4 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 KII90845.1 - 0.031 13.4 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KII90845.1 - 0.033 13.5 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 KII90845.1 - 0.14 11.3 1.5 0.37 9.9 1.5 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase DPBB_1 PF03330.18 KII90846.1 - 4.5e-05 23.6 0.1 6.5e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KII90846.1 - 0.0077 16.1 0.1 0.009 15.9 0.1 1.2 1 0 0 1 1 1 1 Barwin family ProQ_C PF17516.2 KII90846.1 - 0.039 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Cyt-b5 PF00173.28 KII90847.1 - 1.5e-17 63.5 0.0 2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-MYND PF01753.18 KII90849.1 - 2.8e-08 33.7 8.9 4.9e-08 32.9 8.9 1.4 1 0 0 1 1 1 1 MYND finger Tcp11 PF05794.13 KII90850.1 - 7.7e-77 259.2 0.0 9.8e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.25 KII90852.1 - 1.9e-67 227.0 0.0 2.6e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KII90852.1 - 1.2e-12 48.1 0.7 2.2e-12 47.3 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TFCD_C PF12612.8 KII90853.1 - 2.3e-42 145.0 0.1 2.5e-41 141.6 0.0 2.8 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KII90853.1 - 8.6e-05 22.5 11.4 0.042 14.1 0.1 7.1 7 0 0 7 7 7 1 HEAT repeat RIX1 PF08167.12 KII90853.1 - 0.0027 17.5 0.4 3.3 7.4 0.1 3.3 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 KII90853.1 - 0.0028 18.0 11.1 0.056 13.8 0.0 5.7 4 2 2 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KII90853.1 - 0.018 15.1 0.1 0.12 12.4 0.0 2.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 BUD22 PF09073.10 KII90854.1 - 1.3e-85 288.4 26.1 1.5e-85 288.2 26.1 1.0 1 0 0 1 1 1 1 BUD22 ER-remodelling PF14755.6 KII90854.1 - 7.6 6.8 17.3 0.2 11.9 2.5 3.2 3 0 0 3 3 3 0 Intracellular membrane remodeller PP2C PF00481.21 KII90856.1 - 3.6e-79 266.0 0.0 5.3e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KII90856.1 - 0.039 13.9 0.1 0.98 9.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CS PF04969.16 KII90857.1 - 4.2e-07 30.9 0.0 3.9e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 CS domain Aldo_ket_red PF00248.21 KII90858.1 - 3.9e-56 190.4 0.0 4.4e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lactamase_B PF00753.27 KII90861.1 - 1.7e-12 47.8 1.8 2.2e-12 47.4 1.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KII90861.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain F-box-like PF12937.7 KII90862.1 - 4.2e-08 32.9 4.7 1.7e-07 31.0 1.0 2.7 3 0 0 3 3 3 2 F-box-like Oxidored_FMN PF00724.20 KII90863.1 - 1.9e-95 320.0 0.0 2.2e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.24 KII90865.1 - 2.2e-110 369.6 20.4 2.5e-110 369.4 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII90865.1 - 9.6e-23 80.7 32.3 4.4e-17 62.0 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII90865.1 - 0.00012 20.7 0.9 0.00012 20.7 0.9 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.14 KII90867.1 - 2.6e-67 226.7 0.0 3.1e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Kdo PF06293.14 KII90869.1 - 1.2e-06 28.1 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII90869.1 - 0.00032 20.1 0.0 0.0009 18.7 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KII90869.1 - 0.00056 19.6 0.0 0.0016 18.1 0.0 1.5 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 KII90869.1 - 0.0013 18.7 0.4 0.18 11.7 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family WD40 PF00400.32 KII90872.1 - 1.8e-128 414.6 63.1 2.9e-10 40.6 0.4 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90872.1 - 9.3e-43 144.5 11.1 0.0089 16.3 0.0 13.8 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII90872.1 - 3.5e-26 92.3 2.9 0.008 15.5 0.0 10.5 2 2 9 12 12 12 11 WD40-like domain Frtz PF11768.8 KII90872.1 - 4.6e-20 71.4 0.0 0.03 12.6 0.0 8.8 2 1 6 9 9 9 8 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KII90872.1 - 1.2e-17 63.9 15.4 0.33 9.9 0.0 12.6 1 1 13 14 14 14 5 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KII90872.1 - 6.6e-12 45.7 0.2 0.0076 16.1 0.0 5.1 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KII90872.1 - 9.6e-12 44.5 18.5 6 6.9 0.0 12.2 14 0 0 14 14 13 2 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 KII90872.1 - 1.3e-10 41.2 5.5 23 5.1 0.0 11.3 11 3 2 13 13 12 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KII90872.1 - 2.3e-06 26.6 20.1 1.2 7.7 1.6 8.3 1 1 4 9 9 9 3 Nucleoporin Nup120/160 ArlS_N PF18719.1 KII90872.1 - 6.7e-05 23.1 2.0 44 4.3 0.0 6.3 4 2 2 7 7 7 0 ArlS sensor domain PGDH_C PF16896.5 KII90872.1 - 0.00052 20.0 0.1 2.6 8.0 0.0 5.1 2 2 5 7 7 7 1 Phosphogluconate dehydrogenase (decarboxylating) C-term PQQ_3 PF13570.6 KII90872.1 - 0.0017 18.8 7.1 23 5.6 0.0 7.1 7 1 1 8 8 8 0 PQQ-like domain WD40_3 PF15911.5 KII90872.1 - 0.0078 16.2 4.7 44 4.2 0.0 7.2 9 0 0 9 9 9 0 WD domain, G-beta repeat PQQ PF01011.21 KII90872.1 - 0.0082 16.0 3.2 13 5.9 0.0 6.8 8 0 0 8 8 8 0 PQQ enzyme repeat PUB PF09409.10 KII90872.1 - 0.027 14.4 0.0 75 3.4 0.0 3.6 3 0 0 3 3 3 0 PUB domain NACHT PF05729.12 KII90873.1 - 6.8e-06 26.1 0.1 1.4e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII90873.1 - 7.2e-06 26.5 0.0 1.1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KII90873.1 - 0.00063 20.2 0.1 0.0033 17.9 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII90873.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KII90873.1 - 0.02 14.2 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KII90873.1 - 0.03 13.6 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 KII90873.1 - 0.035 14.1 0.0 6 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KII90873.1 - 0.083 12.6 0.2 0.096 12.4 0.2 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KII90873.1 - 0.096 12.1 0.3 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KII90873.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 KII90873.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Ish1 PF10281.9 KII90875.1 - 0.012 15.9 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein HhH-GPD PF00730.25 KII90877.1 - 1.8e-10 41.2 0.0 3.3e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KII90877.1 - 0.0085 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KII90877.1 - 0.06 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Carb_kinase PF01256.17 KII90877.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase IMS_HHH PF11798.8 KII90877.1 - 0.19 12.1 0.0 0.48 10.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif adh_short PF00106.25 KII90878.1 - 5.7e-18 65.1 0.2 2.8e-16 59.6 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII90878.1 - 2.1e-11 43.8 0.0 1e-10 41.6 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90878.1 - 5.2e-05 23.2 0.2 8.5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII90878.1 - 0.038 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII90878.1 - 0.049 13.7 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DHHC PF01529.20 KII90880.1 - 2.1e-30 105.6 15.3 2.1e-30 105.6 15.3 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Orf78 PF06024.12 KII90880.1 - 0.028 14.7 0.6 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Spt4 PF06093.13 KII90880.1 - 0.87 9.7 3.4 1.7 8.8 3.4 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Zn_clus PF00172.18 KII90881.1 - 0.00075 19.6 1.8 0.0015 18.7 1.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MgtC PF02308.16 KII90881.1 - 0.25 11.7 0.6 0.49 10.8 0.6 1.4 1 0 0 1 1 1 0 MgtC family ABC_membrane PF00664.23 KII90882.1 - 3.9e-63 213.7 29.2 5.4e-34 118.1 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII90882.1 - 2.7e-52 176.9 0.0 4.7e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII90882.1 - 4.7e-10 39.3 2.8 0.0041 16.6 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KII90882.1 - 1.6e-08 34.6 1.0 0.0055 16.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KII90882.1 - 4.5e-08 33.3 0.2 0.017 15.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KII90882.1 - 1.4e-06 28.8 0.3 0.015 15.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 KII90882.1 - 1.7e-06 28.2 0.2 0.0047 17.0 0.0 2.7 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 KII90882.1 - 6e-06 25.9 0.3 0.18 11.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KII90882.1 - 7.6e-06 25.9 0.2 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KII90882.1 - 4.9e-05 23.6 0.6 0.24 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KII90882.1 - 0.00011 22.8 0.1 0.18 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KII90882.1 - 0.00013 21.4 0.1 0.093 12.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KII90882.1 - 0.00023 20.5 0.6 0.78 9.0 0.1 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_15 PF13175.6 KII90882.1 - 0.0015 18.4 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 KII90882.1 - 0.0019 18.4 0.1 3.8 7.7 0.1 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KII90882.1 - 0.0029 17.3 0.1 2.5 7.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KII90882.1 - 0.0033 17.5 2.0 0.62 10.1 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KII90882.1 - 0.0036 16.3 0.4 0.78 8.6 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 KII90882.1 - 0.0099 15.4 0.3 5.3 6.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 KII90882.1 - 0.015 14.5 0.7 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 KII90882.1 - 0.02 14.5 0.2 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KII90882.1 - 0.022 15.1 0.0 18 5.8 0.0 3.3 4 0 0 4 4 2 0 RNA helicase AAA_18 PF13238.6 KII90882.1 - 0.023 15.2 0.0 16 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KII90882.1 - 0.037 13.6 0.2 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KII90882.1 - 0.04 13.8 0.5 7.6 6.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 KII90882.1 - 0.051 12.6 0.4 7.8 5.4 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 KII90882.1 - 0.078 12.9 0.1 8.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 KII90882.1 - 0.19 11.5 0.2 18 5.1 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KII90882.1 - 0.21 10.7 3.1 14 4.8 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain TsaE PF02367.17 KII90882.1 - 0.24 11.4 0.4 32 4.5 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 KII90882.1 - 0.27 10.0 0.9 58 2.3 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DNA_pol_A_exo1 PF01612.20 KII90883.1 - 2.1e-44 151.3 0.1 3.4e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KII90883.1 - 4.2e-23 81.8 5.8 1e-22 80.6 1.5 3.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 KII90883.1 - 4.4e-13 49.0 0.1 1.9e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 HRDC domain TATR PF03430.13 KII90883.1 - 0.14 10.5 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Velvet PF11754.8 KII90885.1 - 4e-46 158.0 0.1 5.7e-31 108.3 0.0 2.6 2 1 1 3 3 3 2 Velvet factor DEAD PF00270.29 KII90888.1 - 2.2e-10 40.6 0.0 5.4e-10 39.3 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KII90888.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII90888.1 - 0.033 14.5 0.0 0.34 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain T4SS-DNA_transf PF02534.14 KII90888.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SKN1 PF03935.15 KII90889.1 - 9.2e-190 631.3 2.6 1.1e-189 631.1 2.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PC4 PF02229.16 KII90890.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Avl9 PF09794.9 KII90891.1 - 3.3e-128 427.6 0.0 4.1e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KII90891.1 - 1.3e-08 34.8 3.1 0.00033 20.3 1.8 2.9 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KII90891.1 - 6.1e-08 32.6 0.0 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis MAP65_ASE1 PF03999.12 KII90892.1 - 0.058 12.1 1.7 0.089 11.5 1.7 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HU-CCDC81_bac_2 PF18175.1 KII90892.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Acetyltransf_3 PF13302.7 KII90893.1 - 1.9e-10 41.6 0.0 2.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII90893.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Cullin PF00888.22 KII90894.1 - 7.6e-19 67.8 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KII90894.1 - 5.7e-16 58.8 0.0 2.2e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 GDC-P PF02347.16 KII90894.1 - 0.069 12.0 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Glycine cleavage system P-protein NicO PF03824.16 KII90895.1 - 0.35 10.2 8.5 0.32 10.3 4.2 2.5 2 1 1 3 3 3 0 High-affinity nickel-transport protein MFS_1 PF07690.16 KII90896.1 - 2.5e-10 39.8 44.7 2.5e-10 39.8 44.7 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 KII90899.1 - 4.1e-64 216.5 0.0 6.3e-64 215.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII90899.1 - 9.1e-34 116.9 0.0 3.2e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KII90899.1 - 0.0014 17.7 0.4 0.0038 16.3 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 KII90899.1 - 0.005 16.2 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII90899.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase NPV_P10 PF05531.12 KII90901.1 - 0.004 17.6 0.9 0.26 11.8 0.1 3.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 KII90901.1 - 0.028 14.4 17.3 0.16 12.0 7.8 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0565 PF10561.9 KII90901.1 - 0.31 10.2 1.5 0.45 9.7 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RR_TM4-6 PF06459.12 KII90901.1 - 0.38 10.5 5.5 0.61 9.9 5.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FapA PF03961.13 KII90901.1 - 0.41 9.2 13.5 0.077 11.6 7.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Peptidase_S46 PF10459.9 KII90901.1 - 0.92 8.1 7.1 1.2 7.7 7.1 1.1 1 0 0 1 1 1 0 Peptidase S46 SlyX PF04102.12 KII90901.1 - 1 10.0 10.8 3.5 8.3 0.4 3.7 1 1 1 3 3 3 0 SlyX YabA PF06156.13 KII90901.1 - 6.6 7.4 8.2 66 4.2 0.1 2.6 2 0 0 2 2 2 0 Initiation control protein YabA SNF2_N PF00176.23 KII90902.1 - 8.6e-67 225.3 0.0 1.4e-66 224.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII90902.1 - 2.4e-18 66.5 0.0 4.9e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII90902.1 - 9.9e-07 28.7 0.0 4.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KII90902.1 - 1.5e-05 25.0 0.0 9.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AidB_N PF18158.1 KII90903.1 - 0.014 15.4 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Adaptive response protein AidB N-terminal domain zf-RING_UBOX PF13445.6 KII90908.1 - 1.6e-09 37.6 1.8 1.6e-09 37.6 1.8 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII90908.1 - 1e-08 34.9 1.3 1e-08 34.9 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII90908.1 - 1.6e-08 34.2 3.0 1.6e-08 34.2 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII90908.1 - 5.3e-07 29.7 3.2 5.3e-07 29.7 3.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII90908.1 - 4.5e-06 26.9 3.9 4.5e-06 26.9 3.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII90908.1 - 5.7e-05 22.9 8.1 0.00016 21.4 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KII90908.1 - 6.8e-05 22.7 0.4 6.8e-05 22.7 0.4 2.2 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KII90908.1 - 9.5e-05 22.3 1.0 9.5e-05 22.3 1.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 KII90908.1 - 0.0066 16.2 2.1 0.014 15.2 2.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KII90908.1 - 0.02 15.2 4.5 0.02 15.2 4.5 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Myb_DNA-bind_4 PF13837.6 KII90908.1 - 0.033 14.6 0.2 0.062 13.7 0.2 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-ANAPC11 PF12861.7 KII90908.1 - 0.14 12.3 1.8 0.52 10.4 0.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 KII90908.1 - 0.48 10.2 5.8 0.46 10.3 1.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 KII90908.1 - 7.5 6.5 12.3 17 5.4 5.8 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MCM_lid PF17855.1 KII90910.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 MCM AAA-lid domain GST_N PF02798.20 KII90912.1 - 4.1e-10 39.9 0.0 7.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KII90912.1 - 3.2e-07 30.6 0.0 5.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII90912.1 - 3.7e-07 30.3 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KII90912.1 - 9.1e-06 25.8 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII90912.1 - 0.0013 18.9 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KII90912.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dynamin_N PF00350.23 KII90913.1 - 9e-15 55.1 0.0 2.6e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KII90913.1 - 4.7e-07 29.9 0.1 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 KII90913.1 - 0.00038 19.9 0.3 0.0032 16.8 0.1 2.1 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KII90913.1 - 0.00055 20.5 0.2 0.0092 16.5 0.0 2.6 3 0 0 3 3 3 1 ABC transporter DUF87 PF01935.17 KII90913.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KII90913.1 - 0.0066 16.4 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KII90913.1 - 0.008 15.5 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 KII90913.1 - 0.013 14.6 0.0 0.64 9.0 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 KII90913.1 - 0.075 13.4 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KII90913.1 - 0.078 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KII90913.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TolA_bind_tri PF16331.5 KII90914.1 - 0.044 13.9 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Sad1_UNC PF07738.13 KII90916.1 - 1.6e-22 79.9 0.0 3.6e-22 78.8 0.0 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Pico_P2A PF00947.19 KII90917.1 - 0.017 15.2 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Picornavirus core protein 2A zf-C3HC4 PF00097.25 KII90918.1 - 9.3e-06 25.4 2.0 1.7e-05 24.6 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII90918.1 - 1.2e-05 25.1 4.1 2.5e-05 24.0 4.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII90918.1 - 1.2e-05 25.2 2.1 1.2e-05 25.2 2.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII90918.1 - 2.2e-05 24.7 2.2 4.7e-05 23.6 2.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KII90918.1 - 4.7e-05 23.3 5.1 7.4e-05 22.6 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII90918.1 - 5.3e-05 23.0 2.7 0.0001 22.1 2.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KII90918.1 - 0.00039 20.5 3.4 0.00079 19.5 3.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING EZH2_WD-Binding PF11616.8 KII90918.1 - 0.0045 17.1 0.1 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 WD repeat binding protein EZH2 zf-ANAPC11 PF12861.7 KII90918.1 - 0.0068 16.4 0.5 0.011 15.8 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KII90918.1 - 0.017 14.9 0.5 0.034 13.9 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KII90918.1 - 0.027 14.7 4.3 0.048 14.0 4.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF16 PF01519.16 KII90918.1 - 0.1 13.1 0.4 0.15 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 FYVE PF01363.21 KII90918.1 - 0.19 11.9 2.8 0.72 10.0 2.8 1.9 1 1 0 1 1 1 0 FYVE zinc finger DUF2235 PF09994.9 KII90919.1 - 2.9e-91 305.8 0.0 3.6e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.16 KII90920.1 - 4.2e-18 65.4 65.3 4.5e-16 58.7 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KII90920.1 - 1.6e-05 23.7 12.9 1.6e-05 23.7 12.9 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein N_methyl PF07963.12 KII90920.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.8 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif A_deaminase PF00962.22 KII90921.1 - 1.5e-121 405.8 0.2 2.3e-121 405.1 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Baculo_RING PF05883.11 KII90921.1 - 0.089 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain KAsynt_C_assoc PF16197.5 KII90922.1 - 0.033 14.6 1.1 0.04 14.4 1.1 1.1 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF465 PF04325.13 KII90922.1 - 0.35 10.9 0.3 0.35 10.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF465) APG6_N PF17675.1 KII90922.1 - 1.7 9.2 12.0 4.3 7.9 12.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KII90922.1 - 1.8 9.2 8.4 3.7 8.2 8.4 1.6 1 1 0 1 1 1 0 SlyX Atg14 PF10186.9 KII90923.1 - 4.6e-05 22.6 7.6 4.6e-05 22.6 7.6 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 KII90923.1 - 0.0014 19.2 1.0 0.0014 19.2 1.0 2.1 1 1 1 2 2 2 1 Bone marrow stromal antigen 2 DUF3552 PF12072.8 KII90923.1 - 0.0032 16.9 6.3 0.0041 16.6 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4201 PF13870.6 KII90923.1 - 0.0052 16.5 6.9 0.0069 16.1 6.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Amidoligase_2 PF12224.8 KII90923.1 - 0.016 14.9 0.6 0.018 14.7 0.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme EzrA PF06160.12 KII90923.1 - 0.018 13.2 4.3 0.023 12.9 4.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 KII90923.1 - 0.072 11.0 3.4 0.078 10.9 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KII90923.1 - 0.1 11.5 6.8 0.12 11.2 6.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 KII90923.1 - 0.15 12.6 7.0 0.32 11.5 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 COG5 PF10392.9 KII90923.1 - 0.15 12.3 5.4 0.31 11.2 5.4 1.5 1 1 0 1 1 1 0 Golgi transport complex subunit 5 BRE1 PF08647.11 KII90923.1 - 0.15 12.2 6.1 0.21 11.7 6.1 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 KII90923.1 - 0.16 12.5 4.6 0.95 10.0 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 KII90923.1 - 0.22 11.5 6.3 0.37 10.8 5.7 1.5 1 1 1 2 2 2 0 Laminin Domain II KxDL PF10241.9 KII90923.1 - 0.31 11.3 5.2 0.27 11.5 3.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein FlaC_arch PF05377.11 KII90923.1 - 0.49 10.8 2.5 2.8 8.4 0.2 2.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KII90923.1 - 0.81 9.7 6.7 12 6.0 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 KII90923.1 - 1.5 8.9 5.4 1.6 8.8 4.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TMPIT PF07851.13 KII90923.1 - 2.1 7.5 5.7 2.5 7.2 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein YgaB PF14182.6 KII90923.1 - 3.7 8.0 8.6 2.2 8.8 2.8 2.3 1 1 1 2 2 2 0 YgaB-like protein LRR_4 PF12799.7 KII90924.1 - 0.0016 18.8 1.1 0.41 11.1 0.0 4.5 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII90924.1 - 0.002 18.0 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KII90924.1 - 0.032 14.0 0.0 4.9 7.0 0.0 3.0 2 0 0 2 2 2 0 Leucine rich repeat WD40 PF00400.32 KII90927.1 - 2.5e-15 56.6 5.1 6.4e-08 33.1 0.0 5.4 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII90927.1 - 1.6e-08 34.7 0.0 0.0011 19.2 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KII90927.1 - 0.043 13.4 0.0 0.71 9.4 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain Transposase_21 PF02992.14 KII90928.1 - 3e-09 36.4 0.0 7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 JmjC PF02373.22 KII90929.1 - 0.0028 18.1 0.3 0.0093 16.4 0.3 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase tRNA_deacylase PF04414.12 KII90929.1 - 0.0096 15.5 0.0 0.041 13.4 0.0 1.8 2 0 0 2 2 2 1 D-aminoacyl-tRNA deacylase Mito_carr PF00153.27 KII90930.1 - 2.5e-48 162.0 4.0 1.6e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII90930.1 - 0.011 14.9 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease AMPKBI PF04739.15 KII90931.1 - 3.4e-25 88.1 2.4 3.4e-25 88.1 2.4 3.0 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KII90931.1 - 1.4e-21 76.5 0.0 2.9e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 KII90931.1 - 0.039 14.3 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 KII90931.1 - 0.13 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DEAD PF00270.29 KII90932.1 - 1.6e-20 73.6 0.0 2.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII90932.1 - 3.8e-15 56.2 0.0 8e-13 48.7 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII90932.1 - 1.6e-11 44.7 0.2 4.2e-11 43.4 0.2 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KII90932.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KII90932.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ODC_AZ PF02100.17 KII90932.1 - 0.093 12.7 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Ornithine decarboxylase antizyme CN_hydrolase PF00795.22 KII90933.1 - 2.7e-05 23.6 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Abhydrolase_3 PF07859.13 KII90934.1 - 6.3e-15 55.6 0.1 8.3e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII90934.1 - 1.5e-06 27.9 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KII90934.1 - 1.5e-06 29.0 3.1 2.3e-06 28.4 3.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KII90934.1 - 0.00015 21.3 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KII90934.1 - 0.0042 16.8 1.4 1.7 8.2 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KII90934.1 - 0.0049 16.7 0.0 0.048 13.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.28 KII90934.1 - 0.12 11.2 0.0 5.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 KII90934.1 - 0.18 11.0 1.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PAS_3 PF08447.12 KII90935.1 - 1e-06 28.9 0.0 2.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KII90935.1 - 0.00011 22.2 0.0 0.00037 20.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KII90935.1 - 0.024 14.8 0.0 0.059 13.5 0.0 1.6 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.10 KII90935.1 - 0.082 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 KII90935.1 - 0.17 12.1 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain GCD14 PF08704.10 KII90936.1 - 7.1e-91 304.3 0.6 3.2e-89 298.8 0.6 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KII90936.1 - 3.3e-06 27.0 0.0 2.4e-05 24.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KII90936.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KII90936.1 - 0.0084 17.1 0.2 0.02 15.9 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 KII90936.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 KII90936.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_25 PF13649.6 KII90936.1 - 0.058 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Stathmin PF00836.19 KII90936.1 - 0.085 12.8 2.6 0.16 11.9 2.6 1.4 1 0 0 1 1 1 0 Stathmin family Ubie_methyltran PF01209.18 KII90936.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3847 PF12958.7 KII90936.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) BHD_3 PF10405.9 KII90937.1 - 2e-29 101.8 0.1 5.2e-29 100.5 0.1 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KII90937.1 - 5.3e-21 74.8 0.0 1.2e-19 70.4 0.0 2.4 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KII90937.1 - 1.5e-17 63.1 0.0 3.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KII90937.1 - 5.9e-17 62.4 0.2 5.9e-17 62.4 0.2 4.6 4 2 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KII90937.1 - 5.7e-07 30.0 0.1 7.2e-06 26.4 0.1 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily FYRN PF05964.14 KII90938.1 - 1.2e-17 63.5 0.8 2.6e-17 62.4 0.8 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KII90938.1 - 2.9e-16 59.4 0.5 6.7e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 F/Y rich C-terminus ZapB PF06005.12 KII90938.1 - 0.0023 18.3 2.5 0.0023 18.3 2.5 2.8 3 0 0 3 3 3 1 Cell division protein ZapB AC_N PF16214.5 KII90938.1 - 0.85 8.7 7.9 1.4 8.0 5.7 2.4 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Arm-DNA-bind_5 PF17293.2 KII90938.1 - 6.2 7.3 7.9 1.4 9.4 0.6 2.8 3 0 0 3 3 3 0 Arm DNA-binding domain DUF2207 PF09972.9 KII90939.1 - 0.011 14.5 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FLILHELTA PF10306.9 KII90939.1 - 0.035 14.5 0.1 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Hypothetical protein FLILHELTA DUF5305 PF17231.2 KII90939.1 - 0.13 11.6 1.3 0.18 11.2 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Claudin_2 PF13903.6 KII90939.1 - 0.2 11.4 6.2 0.4 10.4 3.5 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1240 PF06836.12 KII90939.1 - 0.56 10.8 3.7 1.4 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) DUF202 PF02656.15 KII90940.1 - 9.4e-18 64.4 0.5 9.4e-18 64.4 0.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) TMEM141 PF15110.6 KII90940.1 - 0.045 14.3 0.1 0.092 13.3 0.1 1.4 1 0 0 1 1 1 0 TMEM141 protein family Vma12 PF11712.8 KII90940.1 - 0.34 11.0 1.1 0.44 10.6 1.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Asp PF00026.23 KII90941.1 - 3e-21 76.2 7.6 9.3e-16 58.1 2.5 2.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII90941.1 - 0.0053 17.0 1.7 3 8.0 0.7 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KII90941.1 - 0.025 15.1 0.4 0.42 11.2 0.1 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII90941.1 - 0.043 14.5 0.5 0.16 12.6 0.2 2.2 2 0 0 2 2 2 0 Aspartyl protease TMEM52 PF14979.6 KII90941.1 - 0.19 11.6 0.4 13 5.6 0.3 2.3 2 0 0 2 2 2 0 Transmembrane 52 BTB PF00651.31 KII90942.1 - 2.4e-05 24.5 0.0 5.1e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 KII90943.1 - 3.6e-27 95.1 0.0 6.7e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII90943.1 - 1.6e-06 28.1 11.3 3.1e-06 27.2 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADD_DNMT3 PF17980.1 KII90943.1 - 0.16 12.0 2.2 0.35 10.9 2.2 1.5 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Usp PF00582.26 KII90944.1 - 4.5e-21 75.9 0.1 4.5e-21 75.9 0.1 2.0 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.6 KII90944.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Asp PF00026.23 KII90945.1 - 4.2e-19 69.1 0.1 2.1e-13 50.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KII90945.1 - 0.00084 19.9 0.3 1.3 9.7 0.3 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII90945.1 - 0.0046 17.6 0.8 1.1 10.0 0.5 2.9 2 1 0 2 2 2 1 Aspartyl protease Shisa PF13908.6 KII90945.1 - 0.008 16.4 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 KII90945.1 - 0.054 14.1 3.2 0.15 12.7 0.6 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.10 KII90945.1 - 0.061 12.7 4.0 0.12 11.8 4.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sigma_reg_N PF13800.6 KII90945.1 - 0.13 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TAXi_N PF14543.6 KII90945.1 - 0.24 11.6 2.4 14 5.8 0.1 3.3 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Syndecan PF01034.20 KII90945.1 - 0.38 10.7 1.7 0.78 9.7 1.7 1.4 1 0 0 1 1 1 0 Syndecan domain p450 PF00067.22 KII90946.1 - 7.3e-69 232.7 0.0 1.3e-68 231.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_3 PF00933.21 KII90947.1 - 3.2e-54 184.5 0.0 4.4e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KII90947.1 - 2.6e-49 167.9 0.0 4.2e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KII90947.1 - 5.2e-20 71.3 0.6 1e-19 70.4 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AAA PF00004.29 KII90950.1 - 8.5e-41 139.5 0.0 2e-40 138.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KII90950.1 - 5.7e-20 71.0 0.2 1.2e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KII90950.1 - 3.5e-10 39.5 0.1 8e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KII90950.1 - 5.7e-05 23.6 0.2 0.011 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KII90950.1 - 0.00056 19.9 0.2 0.0061 16.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII90950.1 - 0.00058 20.2 1.0 0.1 12.9 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KII90950.1 - 0.00081 19.6 0.1 0.011 15.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KII90950.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 KII90950.1 - 0.0025 17.3 0.1 0.05 13.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.6 KII90950.1 - 0.0031 17.7 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KII90950.1 - 0.011 15.2 0.1 0.04 13.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KII90950.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KII90950.1 - 0.036 13.9 0.1 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KII90950.1 - 0.071 12.8 0.2 0.2 11.3 0.1 1.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KII90950.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) XhlA PF10779.9 KII90950.1 - 7.8 6.8 7.2 27 5.0 3.0 2.7 3 0 0 3 3 2 0 Haemolysin XhlA NuA4 PF09340.10 KII90951.1 - 2e-24 85.3 1.2 2.7e-24 84.8 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Snf7 PF03357.21 KII90951.1 - 0.034 13.7 0.2 0.034 13.7 0.2 1.4 2 0 0 2 2 2 0 Snf7 DUF5471 PF17565.2 KII90951.1 - 0.081 13.2 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Rrp40_N PF18311.1 KII90952.1 - 3.5e-14 52.5 0.3 6.7e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KII90952.1 - 1.8e-10 41.0 0.3 3.3e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 KH domain Mod_r PF07200.13 KII90953.1 - 6.3e-45 152.9 3.3 7.4e-45 152.6 3.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KII90953.1 - 7.7e-05 22.8 0.9 7.7e-05 22.8 0.9 1.9 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Glyco_hydro_61 PF03443.14 KII90954.1 - 1e-47 162.8 0.0 1.3e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DNA_pol_B PF00136.21 KII90956.1 - 1.3e-105 353.8 0.0 4e-105 352.2 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KII90956.1 - 2.2e-20 73.1 0.0 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KII90956.1 - 3.5e-16 59.4 2.2 7.2e-16 58.4 2.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KII90956.1 - 0.0052 15.7 0.1 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral Oxidored_FMN PF00724.20 KII90957.1 - 1.1e-94 317.6 0.0 1.2e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NCA2 PF08637.10 KII90958.1 - 1.8e-80 270.2 0.0 3.9e-80 269.1 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 RSN1_7TM PF02714.15 KII90959.1 - 5.4e-80 268.6 25.9 5.4e-80 268.6 25.9 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KII90959.1 - 4.4e-35 120.8 6.4 4.4e-35 120.8 6.4 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KII90959.1 - 4.7e-30 105.1 0.0 5e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KII90959.1 - 1.3e-11 44.5 0.1 4.5e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Oxidored_FMN PF00724.20 KII90960.1 - 2.6e-95 319.6 0.0 3e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyclin_N PF00134.23 KII90962.1 - 1.2e-09 37.9 0.0 5.6e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain MBOAT_2 PF13813.6 KII90963.1 - 2.7e-09 37.2 8.0 2.7e-09 37.2 8.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family adh_short PF00106.25 KII90965.1 - 8e-32 110.3 0.0 1.4e-26 93.1 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII90965.1 - 9.7e-23 80.9 0.0 4.5e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90965.1 - 1.2e-10 41.6 0.1 1.9e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII90965.1 - 5.8e-10 39.0 0.2 9.6e-10 38.3 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII90965.1 - 4.6e-06 26.3 0.2 8.6e-06 25.4 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KII90965.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KII90965.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CDC37_N PF03234.14 KII90966.1 - 6.2e-43 146.8 0.2 6.1e-42 143.6 0.0 2.4 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KII90966.1 - 3e-31 107.8 0.3 1.2e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KII90966.1 - 2.5e-18 66.0 0.4 1.8e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain CENP-B_dimeris PF09026.10 KII90966.1 - 0.081 13.3 1.1 0.48 10.8 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 KII90966.1 - 0.16 11.7 2.7 0.35 10.6 2.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PgaD PF13994.6 KII90967.1 - 0.023 14.8 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein GWT1 PF06423.12 KII90968.1 - 0.022 14.9 3.0 0.022 14.9 3.0 2.4 2 1 0 2 2 2 0 GWT1 DUF3624 PF12292.8 KII90968.1 - 0.39 11.2 8.5 0.12 12.8 3.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) CPP1-like PF11833.8 KII90968.1 - 1.9 8.1 6.7 0.31 10.7 0.3 2.5 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ni_hydr_CYTB PF01292.20 KII90970.1 - 0.029 14.0 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SRF-TF PF00319.18 KII90971.1 - 1.6e-21 75.5 0.1 2.3e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-C3H1 PF10650.9 KII90972.1 - 0.0025 17.5 2.3 0.0054 16.4 2.3 1.6 1 1 0 1 1 1 1 Putative zinc-finger domain Herpes_pp85 PF04637.12 KII90972.1 - 3.3 6.0 4.7 4.4 5.6 4.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) adh_short PF00106.25 KII90974.1 - 3.8e-29 101.5 0.0 1.6e-23 83.2 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII90974.1 - 4.8e-19 68.9 0.0 1.1e-14 54.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90974.1 - 4.1e-07 30.1 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII90974.1 - 4.4e-05 23.1 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII90974.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII90974.1 - 0.044 13.2 0.1 0.076 12.4 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII90974.1 - 0.08 12.1 0.1 0.14 11.3 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein Nudix_hydro PF18290.1 KII90974.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Nudix hydrolase domain Aldo_ket_red PF00248.21 KII90975.1 - 2.6e-64 217.2 0.0 3.1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 KII90976.1 - 7.2e-32 110.4 0.0 1e-25 90.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII90976.1 - 2.4e-19 69.8 0.0 3.7e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII90976.1 - 1.1e-09 38.5 0.1 1.9e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII90976.1 - 1.3e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII90976.1 - 0.00018 21.0 0.1 0.00035 20.1 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KII90976.1 - 0.045 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KII90976.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2868 PF11067.8 KII90977.1 - 0.77 9.2 5.8 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) VWA PF00092.28 KII90978.1 - 3.8e-09 37.0 0.0 6.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KII90978.1 - 1.1e-06 29.2 0.0 4.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Med25_VWA PF11265.8 KII90978.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A EF_assoc_2 PF08356.12 KII90979.1 - 6.9e-36 122.1 0.0 1.5e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KII90979.1 - 1.2e-30 106.2 0.0 3.2e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 KII90979.1 - 3.4e-29 100.2 1.1 7.7e-29 99.1 1.1 1.6 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 KII90979.1 - 1.4e-17 64.0 0.0 1.4e-10 41.4 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII90979.1 - 7.1e-10 38.6 0.0 0.00026 20.5 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.6 KII90979.1 - 2.8e-09 36.1 1.2 0.00074 19.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.23 KII90979.1 - 1.5e-08 34.7 0.0 0.0014 18.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KII90979.1 - 1.4e-07 30.5 3.6 0.0013 18.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KII90979.1 - 1.5e-07 31.7 1.5 0.00065 20.1 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.6 KII90979.1 - 1.6e-06 28.4 0.0 0.033 14.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KII90979.1 - 3.4e-06 27.6 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KII90979.1 - 1.9e-05 25.2 0.1 0.028 15.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain EF-hand_5 PF13202.6 KII90979.1 - 2.2e-05 23.7 4.9 0.029 13.8 0.1 2.6 2 0 0 2 2 2 2 EF hand RsgA_GTPase PF03193.16 KII90979.1 - 2.3e-05 24.4 0.1 0.23 11.4 0.0 3.7 4 0 0 4 4 4 1 RsgA GTPase AAA_28 PF13521.6 KII90979.1 - 2.8e-05 24.4 0.0 0.055 13.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KII90979.1 - 5.7e-05 23.7 0.0 0.4 11.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 KII90979.1 - 0.00013 21.6 0.0 0.098 12.4 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 KII90979.1 - 0.00015 22.2 0.0 0.26 11.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KII90979.1 - 0.00017 21.7 0.1 1 9.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 KII90979.1 - 0.00028 20.8 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 KII90979.1 - 0.00038 20.3 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 KII90979.1 - 0.00041 19.6 0.0 0.62 9.2 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit Dynamin_N PF00350.23 KII90979.1 - 0.00053 20.1 1.0 6.9 6.7 0.0 3.2 2 1 1 3 3 3 0 Dynamin family SRPRB PF09439.10 KII90979.1 - 0.00058 19.3 0.1 0.39 10.1 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Septin PF00735.18 KII90979.1 - 0.001 18.4 0.0 0.045 13.0 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_7 PF12775.7 KII90979.1 - 0.0015 18.0 0.0 0.078 12.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KII90979.1 - 0.0022 17.8 0.0 0.36 10.6 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KII90979.1 - 0.0023 18.3 0.0 0.88 10.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.17 KII90979.1 - 0.0027 17.5 2.9 8.4 6.1 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 KII90979.1 - 0.0027 17.3 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KII90979.1 - 0.0036 16.5 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Ploopntkinase3 PF18751.1 KII90979.1 - 0.0059 16.6 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 VirE PF05272.11 KII90979.1 - 0.0064 16.2 0.2 4.3 7.0 0.0 3.2 3 1 0 3 3 3 0 Virulence-associated protein E MCM PF00493.23 KII90979.1 - 0.0096 15.0 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 KII90979.1 - 0.012 15.6 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KII90979.1 - 0.012 14.8 0.0 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 KII90979.1 - 0.013 15.2 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NOG1 PF06858.14 KII90979.1 - 0.021 14.6 0.2 1.9 8.3 0.1 2.7 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) FtsK_SpoIIIE PF01580.18 KII90979.1 - 0.024 14.0 0.0 3.7 6.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KII90979.1 - 0.028 14.9 0.1 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KII90979.1 - 0.037 14.0 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EF-hand_10 PF14788.6 KII90979.1 - 0.038 13.9 1.5 0.057 13.3 0.1 1.9 2 0 0 2 2 1 0 EF hand SPARC_Ca_bdg PF10591.9 KII90979.1 - 0.043 14.1 1.7 2.9 8.2 0.0 2.7 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_30 PF13604.6 KII90979.1 - 0.048 13.4 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KII90979.1 - 0.048 13.1 0.0 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KII90979.1 - 0.05 13.3 0.0 2.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KII90979.1 - 0.06 12.6 0.0 9.7 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 KII90979.1 - 0.076 12.6 0.4 3.1 7.4 0.0 3.0 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 KII90979.1 - 0.092 12.1 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 1 0 AIG1 family AAA_14 PF13173.6 KII90979.1 - 0.15 12.1 0.0 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII90979.1 - 0.15 11.9 0.1 6.9 6.5 0.1 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea zf-RVT PF13966.6 KII90980.1 - 0.00033 21.3 0.0 0.00073 20.2 0.0 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase KDZ PF18758.1 KII90983.1 - 1.6e-49 168.5 0.0 2.9e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KII90983.1 - 7.5e-11 42.3 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KII90983.1 - 0.00017 21.7 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII90983.1 - 0.0054 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases RVT_1 PF00078.27 KII90984.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Inhibitor_I29 PF08246.12 KII90985.1 - 0.017 15.6 0.4 1.4 9.5 0.1 2.6 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Baculo_PEP_C PF04513.12 KII90985.1 - 0.024 14.7 1.2 0.095 12.7 0.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 KII90986.1 - 5.2e-09 35.9 0.6 1.5e-08 34.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like DUF2773 PF10971.8 KII90986.1 - 0.071 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) p450 PF00067.22 KII90987.1 - 1.2e-68 232.0 0.0 2.5e-68 230.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 KII90988.1 - 0.0002 21.2 0.2 0.00046 20.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII90988.1 - 0.01 15.7 0.3 0.01 15.7 0.3 1.9 2 0 0 2 2 2 0 F-box domain ANAPC4_WD40 PF12894.7 KII90988.1 - 0.016 15.4 0.0 3.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RCC1_2 PF13540.6 KII90988.1 - 0.079 12.8 0.2 0.079 12.8 0.2 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RasGEF PF00617.19 KII90989.1 - 2.8e-48 164.4 0.0 5.4e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII90989.1 - 2.2e-19 69.7 0.0 7.2e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 KII90989.1 - 8.1e-13 47.8 0.0 2.4e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII90989.1 - 2e-12 46.7 0.0 4.4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII90989.1 - 6.3e-11 41.7 0.0 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ASXH PF13919.6 KII90989.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Asx homology domain Methyltransf_25 PF13649.6 KII90991.1 - 8.9e-16 58.4 0.0 2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII90991.1 - 7.7e-12 45.7 0.0 1.9e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII90991.1 - 9.7e-09 35.3 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII90991.1 - 4.9e-08 32.9 0.0 9.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII90991.1 - 5.5e-07 29.2 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KII90991.1 - 6.6e-06 26.8 0.0 1.6e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KII90991.1 - 0.00016 20.3 0.0 0.00043 19.0 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 KII90991.1 - 0.00046 19.5 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KII90991.1 - 0.03 13.9 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KII90991.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KII90991.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase LRR_4 PF12799.7 KII90992.1 - 0.0028 18.0 0.7 6.5 7.3 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII90992.1 - 0.072 13.7 0.1 14 6.7 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KII90992.1 - 0.19 11.8 0.7 5.1 7.4 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich repeat Clat_adaptor_s PF01217.20 KII90993.1 - 1.3e-56 190.5 3.5 1.4e-56 190.4 3.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 KII90993.1 - 0.068 12.7 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain ArfGap PF01412.18 KII90994.1 - 3.6e-33 114.1 0.3 3.6e-33 114.1 0.3 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UQ_con PF00179.26 KII90998.1 - 2.2e-42 144.1 0.0 2.7e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KII90998.1 - 6.7e-19 67.5 0.9 6.7e-19 67.5 0.9 1.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 KII90998.1 - 0.0067 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.14 KII90998.1 - 0.0089 16.3 0.1 0.015 15.5 0.1 1.3 1 0 0 1 1 1 1 FeoA domain Chitin_synth_2 PF03142.15 KII90999.1 - 1.1e-13 50.7 0.4 3.3e-12 45.8 0.0 2.7 3 0 0 3 3 3 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KII90999.1 - 4.5e-10 39.8 0.3 6.4e-06 26.2 0.2 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KII90999.1 - 4.2e-05 23.6 9.7 4.2e-05 23.6 9.7 3.0 1 1 2 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KII90999.1 - 0.00034 20.2 0.1 0.00061 19.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KII90999.1 - 0.00044 20.1 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Coprogen_oxidas PF01218.18 KII91000.1 - 1.1e-132 441.3 0.0 1.2e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glycos_transf_3 PF00591.21 KII91001.1 - 3.6e-76 256.1 0.0 4.5e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KII91001.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Methyltransf_18 PF12847.7 KII91001.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 KII91001.1 - 0.026 14.0 0.2 0.04 13.4 0.2 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Pro-kuma_activ PF09286.11 KII91002.1 - 6.9e-44 149.6 0.1 1.5e-42 145.3 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII91002.1 - 0.00025 20.4 2.1 0.00041 19.7 2.1 1.2 1 0 0 1 1 1 1 Subtilase family EKLF_TAD2 PF16833.5 KII91002.1 - 4.7 7.3 5.3 0.97 9.5 1.1 2.0 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 2 RNA_polI_A34 PF08208.11 KII91003.1 - 0.26 11.3 5.1 0.63 10.1 5.1 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 KII91003.1 - 0.97 7.6 6.1 1.3 7.2 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HTH_32 PF13565.6 KII91004.1 - 0.0029 18.2 0.1 0.0065 17.1 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 KII91004.1 - 0.0038 17.0 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 KII91004.1 - 0.0047 16.5 0.1 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 KII91004.1 - 0.032 14.2 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 KII91004.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4944 PF16302.5 KII91005.1 - 0.0062 16.6 0.7 0.0098 16.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4944) Helicase_C PF00271.31 KII91007.1 - 1.4e-15 57.6 0.0 3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII91007.1 - 1.5e-13 50.9 0.0 2.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII91007.1 - 0.00016 21.7 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC_6 PF15288.6 KII91007.1 - 0.00054 19.7 1.2 0.0017 18.2 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle T4SS-DNA_transf PF02534.14 KII91007.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Mx_ML PF17536.2 KII91007.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal RPAP1_C PF08620.10 KII91008.1 - 3.6e-21 75.0 0.1 1.1e-20 73.5 0.1 1.9 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KII91008.1 - 2.6e-10 39.9 3.5 5.7e-10 38.8 3.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal Med8 PF10232.9 KII91008.1 - 0.73 9.4 3.3 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Gly-zipper_YMGG PF13441.6 KII91009.1 - 0.077 12.8 46.1 1.1 9.0 10.3 3.7 2 1 1 3 3 3 0 YMGG-like Gly-zipper GSH_synth_ATP PF03917.17 KII91010.1 - 4e-126 420.8 0.0 4.6e-126 420.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KII91010.1 - 1.3e-29 102.6 0.0 2.1e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase GH131_N PF18271.1 KII91011.1 - 1.5e-90 303.3 0.0 1.8e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 KII91011.1 - 0.016 15.0 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase SWI-SNF_Ssr4 PF08549.10 KII91012.1 - 4.7e-23 81.8 10.0 1.7e-16 60.1 0.1 2.1 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 KII91012.1 - 0.004 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 CG-1 domain DivIC PF04977.15 KII91012.1 - 0.21 11.4 1.8 2.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Amino_oxidase PF01593.24 KII91013.1 - 1.6e-40 139.8 0.0 4.9e-40 138.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII91013.1 - 1.9e-09 37.6 0.0 4.7e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KII91013.1 - 0.0094 14.7 0.1 0.027 13.2 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KII91013.1 - 0.044 13.0 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KII91013.1 - 0.045 13.0 0.4 0.072 12.3 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII91013.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII91013.1 - 0.21 10.6 0.3 0.37 9.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KII91013.1 - 0.22 12.1 0.1 0.56 10.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FeoB_associated PF12669.7 KII91015.1 - 0.19 12.1 0.1 0.19 12.1 0.1 1.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Cation_efflux PF01545.21 KII91016.1 - 2.4e-19 69.9 8.3 2.9e-19 69.6 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KII91016.1 - 4.7e-12 45.9 0.2 9.3e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter LapA_dom PF06305.11 KII91016.1 - 0.56 10.0 2.5 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VSP PF03302.13 KII91017.1 - 0.1 11.5 0.3 0.13 11.1 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein MLANA PF14991.6 KII91018.1 - 0.0064 16.8 0.1 0.014 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein melan-A TM_helix PF05552.12 KII91018.1 - 0.13 12.2 1.7 0.21 11.6 1.7 1.3 1 0 0 1 1 1 0 Conserved TM helix Pkinase PF00069.25 KII91019.1 - 9.4e-41 139.9 0.0 6.1e-29 101.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII91019.1 - 7e-26 91.1 0.0 3.5e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII91019.1 - 0.0016 17.3 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII91019.1 - 0.008 15.5 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 KII91019.1 - 0.043 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KII91019.1 - 0.088 12.7 0.1 0.088 12.7 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Antimicrobial18 PF08130.11 KII91019.1 - 0.11 12.6 0.2 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Type A lantibiotic family Macro PF01661.21 KII91020.1 - 1.9e-17 63.4 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Macro domain Proteasome PF00227.26 KII91023.1 - 1.4e-32 112.7 0.0 1.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.9 KII91024.1 - 6.1e-57 192.5 0.9 7.1e-57 192.3 0.9 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal OPT PF03169.15 KII91025.1 - 1e-193 645.4 63.8 1.2e-193 645.2 63.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CrgA PF06781.12 KII91025.1 - 7.7 6.6 12.8 1.2 9.3 0.8 4.4 4 1 0 4 4 4 0 Cell division protein CrgA HisG PF01634.18 KII91027.1 - 4.4e-52 176.2 0.0 7.3e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KII91027.1 - 7.2e-28 96.5 0.1 3.6e-27 94.3 0.0 2.2 3 0 0 3 3 3 1 HisG, C-terminal domain NMT1 PF09084.11 KII91027.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like SLAC1 PF03595.17 KII91028.1 - 7.7e-57 193.0 43.5 8.9e-57 192.8 43.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF21 PF01595.20 KII91028.1 - 8.8 6.0 9.4 1.3 8.7 2.1 2.8 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain HIT PF01230.23 KII91029.1 - 1.5e-24 86.5 0.1 2e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KII91029.1 - 9.9e-10 38.9 0.1 1.5e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KII91029.1 - 0.0017 18.2 0.6 0.003 17.4 0.6 1.6 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DIOX_N PF14226.6 KII91030.1 - 7.1e-31 107.4 0.0 1.1e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91030.1 - 2.2e-19 69.8 0.0 3.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.20 KII91031.1 - 8.1e-134 447.3 0.0 1.1e-133 446.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KII91031.1 - 0.0057 16.3 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase M50B-like TAT_signal PF10518.9 KII91031.1 - 0.011 15.6 0.5 0.024 14.5 0.5 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Med30 PF11315.8 KII91031.1 - 0.15 12.2 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 DUF4332 PF14229.6 KII91032.1 - 0.052 13.8 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) NUMOD1 PF07453.13 KII91034.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain NFACT-R_1 PF05670.13 KII91035.1 - 3e-42 143.7 0.0 5e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain RRM_1 PF00076.22 KII91036.1 - 3.5e-10 39.6 0.0 1.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KII91036.1 - 0.00019 21.6 0.3 0.00038 20.7 0.3 1.5 1 0 0 1 1 1 1 PWI domain COesterase PF00135.28 KII91038.1 - 1.4e-91 307.9 0.0 4.4e-90 303.0 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII91038.1 - 5.7e-05 23.1 0.1 0.00029 20.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII91038.1 - 0.019 14.4 1.3 0.16 11.4 0.6 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family Amino_oxidase PF01593.24 KII91039.1 - 2.3e-37 129.4 0.0 3.8e-27 95.7 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII91039.1 - 1.9e-08 34.4 0.0 5.2e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII91039.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII91039.1 - 0.034 12.8 0.0 0.29 9.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KII91039.1 - 0.079 12.2 0.2 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3071 PF11268.8 KII91039.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Peroxidase_2 PF01328.17 KII91040.1 - 3.3e-47 161.4 0.0 4.6e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 FAD_binding_3 PF01494.19 KII91041.1 - 2.1e-70 237.7 0.0 3.1e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII91041.1 - 7e-09 35.3 2.4 1e-05 24.9 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII91041.1 - 2.5e-06 26.8 0.1 1.8e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KII91041.1 - 1.4e-05 25.2 0.1 4.9e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KII91041.1 - 1.5e-05 23.9 0.3 0.00013 20.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KII91041.1 - 0.00028 20.6 0.4 0.0068 16.0 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KII91041.1 - 0.00064 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KII91041.1 - 0.00088 19.8 0.3 1.1 9.9 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII91041.1 - 0.0012 18.2 0.1 0.0021 17.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KII91041.1 - 0.0049 16.3 0.0 0.0081 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII91041.1 - 0.0097 15.2 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KII91041.1 - 0.011 15.1 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KII91041.1 - 0.039 14.0 0.1 0.097 12.7 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KII91041.1 - 0.068 12.2 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Glu_dehyd_C PF16912.5 KII91041.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KII91041.1 - 0.078 11.8 0.5 0.19 10.5 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KII91041.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding AAA PF00004.29 KII91042.1 - 5.1e-38 130.5 0.0 9.5e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII91042.1 - 3.5e-07 29.9 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KII91042.1 - 2.4e-06 27.4 0.0 7.2e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KII91042.1 - 9.1e-06 26.2 0.2 0.00033 21.1 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KII91042.1 - 3.3e-05 24.1 0.0 7.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KII91042.1 - 8.1e-05 22.6 0.2 0.00077 19.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII91042.1 - 0.00014 22.2 0.1 0.0035 17.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KII91042.1 - 0.00027 20.9 0.1 0.00067 19.6 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 KII91042.1 - 0.00029 20.9 0.0 0.00096 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KII91042.1 - 0.00043 20.8 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KII91042.1 - 0.00053 19.4 0.2 0.0014 18.1 0.2 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KII91042.1 - 0.00053 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KII91042.1 - 0.00084 18.8 0.0 1.1 8.6 0.0 3.1 2 1 1 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 KII91042.1 - 0.00085 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 KII91042.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KII91042.1 - 0.0018 18.5 0.1 0.0044 17.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KII91042.1 - 0.0025 17.4 0.1 0.011 15.3 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KII91042.1 - 0.0033 16.7 0.1 0.0056 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 KII91042.1 - 0.0049 16.6 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KII91042.1 - 0.0074 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Hydin_ADK PF17213.3 KII91042.1 - 0.008 16.5 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 KII91042.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KII91042.1 - 0.011 15.1 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KII91042.1 - 0.014 15.1 0.0 0.042 13.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KII91042.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KII91042.1 - 0.018 14.7 0.1 0.084 12.4 0.2 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KII91042.1 - 0.019 15.1 0.0 0.049 13.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KII91042.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KII91042.1 - 0.03 14.9 0.1 0.078 13.5 0.1 1.7 1 0 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 KII91042.1 - 0.056 13.3 0.0 0.38 10.5 0.0 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 KII91042.1 - 0.06 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KII91042.1 - 0.076 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KII91042.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KII91042.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.22 KII91042.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Guanylate_kin PF00625.21 KII91042.1 - 0.19 11.4 0.0 0.87 9.3 0.0 2.1 3 0 0 3 3 2 0 Guanylate kinase Glyco_hydro_20 PF00728.22 KII91043.1 - 1.1e-83 281.5 0.0 1.3e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KII91043.1 - 1.7e-12 48.2 0.0 3.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KII91043.1 - 7.6e-06 26.7 0.0 2.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ALG11_N PF15924.5 KII91044.1 - 3.8e-89 298.3 0.1 5.2e-89 297.8 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KII91044.1 - 2.5e-23 82.5 0.0 3.5e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KII91044.1 - 3.7e-13 50.1 0.3 7.3e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DAO PF01266.24 KII91045.1 - 2.1e-44 152.6 0.1 2.4e-44 152.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII91045.1 - 0.0004 19.7 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII91045.1 - 0.00053 20.5 0.0 1.9 9.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91045.1 - 0.00083 19.5 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KII91045.1 - 0.0014 18.6 0.0 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KII91045.1 - 0.029 13.6 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KII91045.1 - 0.17 10.7 0.0 7.6 5.3 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Peptidase_M20 PF01546.28 KII91046.1 - 6.9e-33 114.1 0.0 9.6e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KII91046.1 - 3.3e-10 39.8 0.0 7.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KII91046.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 FMN_dh PF01070.18 KII91047.1 - 1.1e-108 363.4 0.0 1.3e-108 363.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KII91047.1 - 3.3e-05 23.3 0.2 0.018 14.4 0.0 3.6 4 1 0 4 4 4 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 KII91047.1 - 3.6e-05 22.9 0.5 0.00023 20.3 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KII91047.1 - 0.00017 20.8 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DEAD PF00270.29 KII91049.1 - 4.4e-06 26.6 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.14 KII91049.1 - 0.092 11.5 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SUR7 PF06687.12 KII91051.1 - 4.3e-16 59.2 18.9 9.7e-16 58.0 18.7 1.6 1 1 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KII91051.1 - 0.0078 16.0 0.2 0.013 15.3 0.2 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BatD PF13584.6 KII91051.1 - 0.058 12.2 0.8 1.6 7.4 0.0 2.2 2 1 0 2 2 2 0 Oxygen tolerance DuoxA PF10204.9 KII91051.1 - 0.64 9.0 11.3 0.011 14.7 4.4 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor PhoLip_ATPase_C PF16212.5 KII91051.1 - 2 8.1 9.7 0.094 12.5 4.2 1.5 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal EphA2_TM PF14575.6 KII91051.1 - 2.5 9.0 0.0 2.5 9.0 0.0 2.8 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pyr_redox_2 PF07992.14 KII91052.1 - 5.2e-53 180.2 0.0 6e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII91052.1 - 6.1e-19 68.4 0.4 1.1e-15 58.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII91052.1 - 1.7e-17 63.7 0.1 1.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII91052.1 - 2.2e-05 23.8 0.1 0.00011 21.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KII91052.1 - 2.2e-05 24.6 0.1 0.0026 18.0 0.0 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII91052.1 - 5.8e-05 22.8 0.6 0.097 12.2 0.2 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII91052.1 - 0.00022 20.5 1.7 0.0027 16.9 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KII91052.1 - 0.00032 20.2 0.0 0.0057 16.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KII91052.1 - 0.00042 19.5 5.3 0.0053 15.9 0.2 3.8 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KII91052.1 - 0.00058 19.2 0.1 0.032 13.5 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KII91052.1 - 0.00063 20.2 0.1 0.076 13.5 0.0 2.9 2 2 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KII91052.1 - 0.0012 18.9 0.1 3.5 7.7 0.0 3.4 4 0 0 4 4 4 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KII91052.1 - 0.0014 17.9 0.1 0.2 10.7 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KII91052.1 - 0.0025 16.6 0.6 0.042 12.6 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.14 KII91052.1 - 0.0055 15.6 0.4 0.06 12.2 0.2 2.5 2 1 1 3 3 3 1 Tryptophan halogenase ApbA PF02558.16 KII91052.1 - 0.012 15.3 0.5 4.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KII91052.1 - 0.012 16.2 0.0 0.65 10.6 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KII91052.1 - 0.091 12.0 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KII91052.1 - 0.093 12.7 0.3 20 5.1 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding IlvN PF07991.12 KII91052.1 - 0.12 12.0 0.0 7.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ATP-synt_C PF00137.21 KII91053.1 - 8.8e-35 118.9 35.8 4.7e-22 78.1 16.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Sad1_UNC PF07738.13 KII91054.1 - 1.8e-26 92.7 0.0 6e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal WD40 PF00400.32 KII91056.1 - 4.3e-40 134.9 14.9 2.2e-09 37.8 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91056.1 - 2.7e-11 43.6 0.2 0.003 17.8 0.0 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII91056.1 - 3.8e-06 25.8 1.6 0.13 10.9 0.2 3.6 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KII91056.1 - 0.00081 18.4 0.4 12 4.7 0.0 3.9 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KII91056.1 - 0.0088 15.0 0.1 0.022 13.7 0.1 1.7 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain MMS1_N PF10433.9 KII91056.1 - 0.018 13.7 0.0 2.2 6.8 0.0 3.0 1 1 3 4 4 4 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoporin_N PF08801.11 KII91056.1 - 0.058 12.1 0.2 2.1 7.0 0.0 3.2 2 2 0 2 2 2 0 Nup133 N terminal like Hira PF07569.11 KII91056.1 - 0.073 12.8 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split CDC48_2 PF02933.17 KII91057.1 - 2.8e-05 23.8 0.1 0.7 9.7 0.0 4.1 2 1 2 4 4 4 3 Cell division protein 48 (CDC48), domain 2 ChpA-C PF03777.13 KII91057.1 - 0.013 15.4 6.2 1.9 8.4 0.1 3.9 3 1 1 4 4 4 0 ChpA-C Tetraspanin PF00335.20 KII91058.1 - 5.3e-11 42.7 6.9 7.3e-11 42.2 6.9 1.2 1 0 0 1 1 1 1 Tetraspanin family CcmH PF03918.14 KII91058.1 - 0.81 9.0 3.1 0.33 10.2 0.2 1.8 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Peptidase_M3 PF01432.20 KII91059.1 - 2.9e-115 386.1 0.0 4.2e-115 385.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KII91059.1 - 0.089 12.4 0.6 0.15 11.6 0.6 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WD40 PF00400.32 KII91061.1 - 0.00014 22.6 1.7 0.92 10.5 0.0 5.5 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91061.1 - 0.00059 20.1 0.1 2.5 8.5 0.0 4.0 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Atypical_Card PF18461.1 KII91061.1 - 0.075 13.3 0.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 Atypical caspase recruitment domain Glyco_hydro_20 PF00728.22 KII91062.1 - 4.8e-81 272.9 0.0 2.2e-78 264.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KII91062.1 - 1.5e-15 58.1 0.0 3.3e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KII91062.1 - 8.7e-07 29.8 0.0 5.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.22 KII91063.1 - 1.2e-92 311.1 0.0 1.4e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KII91063.1 - 3e-16 60.3 0.0 7.5e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KII91063.1 - 5.4e-09 36.9 0.1 1.8e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 GHL6 PF14871.6 KII91063.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 ENTH PF01417.20 KII91065.1 - 5.1e-44 149.3 0.1 7.3e-44 148.8 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KII91065.1 - 0.048 12.6 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 ANTH domain RNA_pol_Rpb4 PF03874.16 KII91067.1 - 1.6e-22 80.1 0.4 2.4e-22 79.6 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 NOT2_3_5 PF04153.18 KII91068.1 - 8.9e-31 106.7 1.1 8.9e-31 106.7 1.1 1.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.21 KII91069.1 - 5.8e-33 112.3 8.7 4.6e-09 35.9 1.0 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KII91069.1 - 0.0036 16.4 0.0 0.22 10.6 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Atg14 PF10186.9 KII91070.1 - 0.028 13.5 6.8 0.042 12.9 6.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rab5-bind PF09311.11 KII91070.1 - 0.038 13.4 4.8 0.054 12.9 4.8 1.2 1 0 0 1 1 1 0 Rabaptin-like protein PRKG1_interact PF15898.5 KII91070.1 - 0.068 14.1 1.1 0.068 14.1 1.1 2.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF3450 PF11932.8 KII91070.1 - 0.35 10.1 9.8 1.1 8.5 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 KII91071.1 - 2.8e-47 161.3 0.0 6.7e-47 160.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91071.1 - 5.4e-29 101.3 0.0 6.1e-28 97.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII91071.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KII91071.1 - 0.001 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII91071.1 - 0.0011 18.9 0.3 0.0033 17.4 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII91071.1 - 0.0012 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 KII91071.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LRR_8 PF13855.6 KII91072.1 - 0.073 12.8 3.5 0.2 11.5 0.7 3.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KII91072.1 - 0.53 10.8 4.5 0.51 10.8 0.3 3.3 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) FMO-like PF00743.19 KII91073.1 - 4e-17 61.9 0.2 8.9e-16 57.4 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KII91073.1 - 1.4e-12 47.5 0.6 4.9e-10 39.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KII91073.1 - 4.1e-12 45.9 0.0 3.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91073.1 - 1.2e-08 35.1 0.6 3.3e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KII91073.1 - 1.8e-06 27.4 0.6 6.1e-05 22.4 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII91073.1 - 0.012 15.6 0.3 1.2 9.2 0.0 3.0 3 1 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KII91073.1 - 0.012 15.2 0.3 0.43 10.1 0.2 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase SPR1 PF15356.6 KII91074.1 - 0.92 10.0 8.3 0.31 11.6 4.9 1.9 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Palm_thioest PF02089.15 KII91077.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF4640 PF15480.6 KII91077.1 - 0.0051 16.6 2.1 0.011 15.6 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4640) DUF676 PF05057.14 KII91077.1 - 0.0055 16.2 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 KII91077.1 - 0.015 14.9 0.1 0.096 12.3 0.1 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 KII91077.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UL42 PF17638.2 KII91077.1 - 0.088 12.8 0.3 0.27 11.2 0.3 1.8 1 0 0 1 1 1 0 HCMV UL42 ST7 PF04184.12 KII91077.1 - 2.3 6.6 5.0 2.1 6.7 2.8 1.8 2 0 0 2 2 2 0 ST7 protein Velvet PF11754.8 KII91078.1 - 6.4e-38 131.1 0.0 8.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor ELFV_dehydrog PF00208.21 KII91079.1 - 7.5e-57 192.8 0.0 1e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KII91079.1 - 3.2e-18 64.8 0.0 5.1e-12 44.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase adh_short PF00106.25 KII91080.1 - 1.1e-45 155.5 0.3 1.4e-45 155.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91080.1 - 1.5e-35 122.8 0.1 1.9e-35 122.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91080.1 - 4.8e-09 36.4 0.1 7.6e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 KII91080.1 - 0.0049 16.1 0.0 0.38 10.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 KII91080.1 - 0.021 14.7 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF1776 PF08643.10 KII91080.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3012 PF11216.8 KII91080.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) 3HCDH_N PF02737.18 KII91080.1 - 0.078 12.9 0.6 0.12 12.2 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DpaA_N PF16924.5 KII91080.1 - 0.091 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain SAM_2 PF07647.17 KII91081.1 - 1.3e-07 31.7 0.0 4.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KII91081.1 - 0.00016 22.0 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 KII91081.1 - 0.079 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1281 PF06924.11 KII91081.1 - 0.16 11.5 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) FAD_binding_7 PF03441.14 KII91082.1 - 4.1e-43 147.2 0.4 6.5e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KII91082.1 - 1.7e-20 73.7 0.0 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Acetyltransf_3 PF13302.7 KII91083.1 - 9.7e-09 36.0 0.0 1.4e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII91083.1 - 0.17 12.1 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Flavoprotein PF02441.19 KII91084.1 - 3.7e-52 176.2 0.0 4.2e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein DUF3605 PF12239.8 KII91085.1 - 5.6e-28 98.2 0.0 2.4e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) Mob1_phocein PF03637.17 KII91086.1 - 7.3e-67 224.6 0.4 8.9e-67 224.3 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family TPR_MLP1_2 PF07926.12 KII91087.1 - 4.8e-25 88.1 22.8 4.8e-25 88.1 22.8 18.5 5 3 11 18 18 18 7 TPR/MLP1/MLP2-like protein Pkinase PF00069.25 KII91088.1 - 5.9e-42 143.8 0.0 2.1e-41 142.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91088.1 - 2.7e-20 72.8 0.0 8.6e-20 71.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII91088.1 - 0.00028 20.9 0.1 0.0009 19.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII91088.1 - 0.00035 20.0 0.0 0.00078 18.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like EXOSC1 PF10447.9 KII91088.1 - 0.21 12.2 2.3 0.67 10.6 2.3 1.8 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 ABC_tran PF00005.27 KII91089.1 - 5.9e-46 156.4 0.0 2.1e-27 96.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII91089.1 - 1.6e-39 136.2 22.6 2.9e-19 69.8 8.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KII91089.1 - 7.2e-13 48.5 1.3 0.0027 17.2 0.2 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII91089.1 - 1.6e-06 28.6 0.4 0.082 13.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KII91089.1 - 3.8e-06 26.9 5.1 0.0095 15.8 0.2 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KII91089.1 - 1e-05 26.2 2.1 0.00084 19.9 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII91089.1 - 2.6e-05 23.9 2.0 0.053 13.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KII91089.1 - 2.7e-05 23.8 0.0 0.22 11.1 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KII91089.1 - 0.00021 21.6 0.0 0.21 11.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 KII91089.1 - 0.0006 19.0 0.0 0.091 11.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KII91089.1 - 0.0011 18.6 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KII91089.1 - 0.0012 18.9 0.4 0.38 10.9 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 KII91089.1 - 0.003 17.7 2.7 0.061 13.4 0.3 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII91089.1 - 0.0035 16.7 0.2 0.77 9.1 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KII91089.1 - 0.01 15.7 0.1 5 7.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 KII91089.1 - 0.027 14.2 0.0 2.5 7.8 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KII91089.1 - 0.028 13.9 1.3 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KII91089.1 - 0.034 14.1 0.2 12 5.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 KII91089.1 - 0.036 14.1 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KII91089.1 - 0.037 13.8 0.4 14 5.4 0.0 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 KII91089.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain MeaB PF03308.16 KII91089.1 - 0.11 11.4 0.1 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KII91089.1 - 0.11 12.6 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KII91089.1 - 0.12 12.1 0.2 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KII91089.1 - 0.15 10.9 1.0 11 4.8 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 KII91089.1 - 0.23 11.5 1.0 7.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 KII91090.1 - 2.4e-108 362.5 0.0 2.9e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91090.1 - 5.9e-10 38.9 0.3 1.1e-06 28.2 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_25 PF13481.6 KII91090.1 - 0.012 15.1 0.2 0.064 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KII91090.1 - 0.015 15.5 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KII91090.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KII91090.1 - 0.028 13.9 0.1 0.65 9.5 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KII91090.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KII91090.1 - 0.17 11.2 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Transferase PF02458.15 KII91091.1 - 3e-34 118.5 0.0 5.4e-13 48.4 0.0 3.1 3 0 0 3 3 3 3 Transferase family KRE9 PF05390.11 KII91091.1 - 0.16 12.7 0.7 0.34 11.7 0.7 1.6 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 AAA_5 PF07728.14 KII91092.1 - 4.2e-113 373.4 0.0 8.5e-21 74.4 0.0 9.4 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KII91092.1 - 5.4e-51 171.3 4.0 6.5e-16 58.5 0.0 5.9 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KII91092.1 - 1.4e-25 89.4 0.0 5.2e-25 87.6 0.0 2.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 KII91092.1 - 3.1e-25 88.5 0.0 2e-07 31.0 0.0 8.0 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KII91092.1 - 4.5e-21 75.7 0.0 0.00036 21.0 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KII91092.1 - 2.1e-20 73.0 0.3 1.3e-05 24.8 0.0 6.2 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA_16 PF13191.6 KII91092.1 - 4.2e-20 72.8 15.4 6.6e-05 23.4 0.1 7.3 6 2 1 7 7 6 5 AAA ATPase domain AAA_6 PF12774.7 KII91092.1 - 5.1e-18 65.1 0.0 0.0028 16.7 0.0 7.9 8 1 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KII91092.1 - 1.6e-17 64.1 0.2 0.0081 16.4 0.1 6.8 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 KII91092.1 - 8.1e-17 61.4 0.0 0.0032 17.5 0.0 6.7 6 0 0 6 6 6 4 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 KII91092.1 - 7.5e-16 58.9 0.1 0.053 14.1 0.0 5.8 5 0 0 5 5 5 3 AAA domain Sigma54_activat PF00158.26 KII91092.1 - 2.8e-15 56.4 0.0 0.01 15.6 0.0 5.2 5 0 0 5 5 4 4 Sigma-54 interaction domain AAA_30 PF13604.6 KII91092.1 - 1.6e-13 50.8 0.3 5.8e-05 22.9 0.0 6.2 6 0 0 6 6 5 1 AAA domain T2SSE PF00437.20 KII91092.1 - 9.9e-12 44.5 0.2 0.0039 16.3 0.0 5.5 5 0 0 5 5 5 2 Type II/IV secretion system protein TsaE PF02367.17 KII91092.1 - 2.1e-11 43.9 0.3 0.72 9.9 0.0 5.5 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KII91092.1 - 2e-10 40.8 0.0 0.077 13.0 0.0 6.6 7 0 0 7 7 6 2 AAA domain Sigma54_activ_2 PF14532.6 KII91092.1 - 4.1e-10 39.9 0.0 0.013 15.6 0.0 4.8 4 0 0 4 4 4 2 Sigma-54 interaction domain ABC_tran PF00005.27 KII91092.1 - 2.6e-09 37.7 1.9 0.053 14.0 0.0 5.5 6 0 0 6 6 4 2 ABC transporter AAA_28 PF13521.6 KII91092.1 - 2.8e-08 34.2 3.1 0.93 9.7 0.0 5.5 6 0 0 6 6 4 2 AAA domain RNA_helicase PF00910.22 KII91092.1 - 3.2e-08 33.9 0.1 3.6 8.0 0.0 5.6 5 0 0 5 5 5 0 RNA helicase Mg_chelatase PF01078.21 KII91092.1 - 1.2e-07 31.3 0.1 7.8 5.8 0.0 6.5 7 0 0 7 7 6 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KII91092.1 - 2e-07 31.3 0.0 5.3 7.2 0.0 5.7 5 0 0 5 5 5 0 AAA domain AAA_25 PF13481.6 KII91092.1 - 4.3e-07 29.7 5.1 0.45 10.0 0.4 5.2 5 0 0 5 5 5 1 AAA domain NACHT PF05729.12 KII91092.1 - 5.1e-07 29.8 0.0 0.81 9.6 0.0 4.8 6 0 0 6 6 3 2 NACHT domain AAA_19 PF13245.6 KII91092.1 - 1.7e-06 28.4 6.5 0.38 11.1 0.1 5.6 4 1 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KII91092.1 - 2.4e-06 27.2 0.4 4.3 7.2 0.1 5.2 5 0 0 5 5 5 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KII91092.1 - 4.9e-06 26.4 0.7 0.78 9.4 0.0 5.4 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.12 KII91092.1 - 8.8e-06 25.6 0.8 2.4 7.9 0.0 5.4 7 0 0 7 7 5 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 KII91092.1 - 2.1e-05 23.9 0.0 6.5 6.0 0.0 5.6 6 0 0 6 6 6 0 Zeta toxin DUF815 PF05673.13 KII91092.1 - 2.4e-05 23.6 0.0 1.9 7.6 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF815) TniB PF05621.11 KII91092.1 - 6.4e-05 22.4 0.0 2.2 7.6 0.0 5.2 5 0 0 5 5 5 1 Bacterial TniB protein Roc PF08477.13 KII91092.1 - 0.00012 22.3 0.5 2.6 8.3 0.0 4.5 5 0 0 5 5 4 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 KII91092.1 - 0.00014 21.7 0.0 0.9 9.3 0.0 4.3 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KII91092.1 - 0.00023 20.8 0.1 7.3 6.2 0.0 4.3 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KII91092.1 - 0.00031 20.5 0.0 7.1 6.3 0.0 5.0 6 0 0 6 6 5 0 AAA domain ATPase_2 PF01637.18 KII91092.1 - 0.00093 19.2 0.0 1.6 8.6 0.0 4.5 5 0 0 5 5 5 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KII91092.1 - 0.001 18.9 0.3 16 5.2 0.0 4.6 5 0 0 5 5 5 0 AAA domain AAA_23 PF13476.6 KII91092.1 - 0.0014 19.1 0.4 14 6.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 KII91092.1 - 0.0015 18.4 3.1 6 6.7 0.1 5.4 6 1 1 7 7 5 0 NTPase DEAD PF00270.29 KII91092.1 - 0.0024 17.7 0.1 5.5 6.7 0.0 3.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 KII91092.1 - 0.0033 17.3 1.5 4.9 7.0 0.0 3.9 4 0 0 4 4 3 0 RsgA GTPase TIP49 PF06068.13 KII91092.1 - 0.0038 16.5 0.1 7.4 5.7 0.0 3.8 5 0 0 5 5 3 0 TIP49 P-loop domain cobW PF02492.19 KII91092.1 - 0.0045 16.6 1.6 25 4.4 0.0 5.1 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KII91092.1 - 0.0052 16.8 0.0 7.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KII91092.1 - 0.0057 16.4 0.1 0.45 10.2 0.0 3.9 6 0 0 6 6 3 1 Viral (Superfamily 1) RNA helicase AAA_8 PF12780.7 KII91092.1 - 0.0073 15.7 0.7 2 7.7 0.0 4.2 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 CbiA PF01656.23 KII91092.1 - 0.01 15.9 1.0 2 8.5 0.2 3.3 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KII91092.1 - 0.026 14.6 0.8 15 5.7 0.0 4.5 5 0 0 5 5 5 0 50S ribosome-binding GTPase IPT PF01745.16 KII91092.1 - 0.038 13.4 0.1 13 5.1 0.0 3.5 4 0 0 4 4 4 0 Isopentenyl transferase dNK PF01712.19 KII91092.1 - 0.055 13.3 1.7 5.7 6.7 0.0 4.0 5 0 0 5 5 5 0 Deoxynucleoside kinase Bac_DnaA PF00308.18 KII91092.1 - 0.06 13.2 0.0 21 4.8 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein ATPase PF06745.13 KII91092.1 - 0.14 11.4 0.8 26 4.1 0.1 3.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 KII91092.1 - 0.17 11.3 0.4 9.3 5.6 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein AAA_9 PF12781.7 KII91092.1 - 0.2 10.8 0.0 17 4.4 0.0 4.0 4 0 0 4 4 4 0 ATP-binding dynein motor region UvrD-helicase PF00580.21 KII91092.1 - 0.41 10.1 1.0 30 4.0 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain LRR_6 PF13516.6 KII91093.1 - 2.7e-09 36.3 13.0 0.4 10.9 0.0 7.4 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 KII91093.1 - 2.5e-05 24.6 8.0 0.28 11.7 1.9 4.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII91093.1 - 0.0006 20.0 1.9 52 5.0 0.0 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KII91093.1 - 0.95 9.3 14.3 21 4.9 2.0 4.9 5 1 0 5 5 5 0 Leucine rich repeat Phosphodiest PF01663.22 KII91095.1 - 2.5e-76 257.6 2.0 3.3e-76 257.2 2.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase OppC_N PF12911.7 KII91095.1 - 0.00027 20.8 0.1 0.00054 19.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C Ysc84 PF04366.12 KII91096.1 - 9.3e-46 154.7 0.0 1.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 KII91096.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Sec7 domain Nup160 PF11715.8 KII91097.1 - 0.0031 16.2 0.0 0.015 14.0 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin Nup120/160 SPR1 PF15356.6 KII91100.1 - 0.38 11.3 5.1 0.78 10.3 5.1 1.5 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 BIR PF00653.21 KII91107.1 - 1.1e-33 115.7 3.4 7.2e-17 61.8 1.0 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KII91107.1 - 4.4e-05 23.5 0.5 0.095 12.7 0.0 2.5 3 1 0 3 3 3 2 C3HC zinc finger-like zf-BED PF02892.15 KII91107.1 - 0.0027 17.7 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 BED zinc finger RNA_pol_N PF01194.17 KII91107.1 - 0.058 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit WAPL PF07814.13 KII91108.1 - 4.7e-08 32.2 0.2 3.9e-07 29.2 0.2 2.4 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Lactamase_B_2 PF12706.7 KII91109.1 - 1.2e-13 51.0 0.2 3e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KII91109.1 - 3e-09 36.4 0.0 3.2e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KII91109.1 - 0.3 11.1 1.6 1.3 9.0 1.4 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Mif2_N PF15624.6 KII91109.1 - 9.2 7.0 10.4 28 5.4 5.7 2.6 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF3433 PF11915.8 KII91113.1 - 6.6e-20 71.4 3.1 6.6e-20 71.4 3.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) GMC_oxred_N PF00732.19 KII91114.1 - 1.4e-57 195.3 0.0 2.7e-57 194.4 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII91114.1 - 1.5e-30 106.6 0.0 2.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KII91114.1 - 0.00084 18.5 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII91114.1 - 0.0016 18.6 0.1 0.0058 16.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII91114.1 - 0.0062 15.7 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII91114.1 - 0.0099 15.5 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII91114.1 - 0.017 14.4 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KII91114.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII91114.1 - 0.25 10.0 0.1 0.47 9.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pmp3 PF01679.17 KII91116.1 - 1.1e-23 83.1 10.4 1.3e-23 82.9 10.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MutS_V PF00488.21 KII91117.1 - 1.7e-82 276.1 0.1 2.8e-82 275.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KII91117.1 - 7.8e-35 120.8 2.8 7.8e-35 120.8 2.8 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KII91117.1 - 3e-17 62.8 1.2 8.8e-17 61.2 1.2 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KII91117.1 - 6.8e-17 62.0 0.1 1.7e-15 57.5 0.0 2.8 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KII91117.1 - 4e-09 36.7 0.0 1.3e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain I AAA_23 PF13476.6 KII91117.1 - 8.6 6.8 7.0 2.5 8.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain zf-MYND PF01753.18 KII91118.1 - 3.6e-07 30.2 11.8 9.3e-07 28.8 11.8 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII91118.1 - 1 9.7 8.1 2.4 8.5 8.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Methyltr_RsmB-F PF01189.17 KII91119.1 - 9.6e-33 113.5 0.0 6.6e-25 87.9 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KII91119.1 - 0.03 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.25 KII91120.1 - 4.4e-15 55.8 0.0 6.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91120.1 - 1.9e-11 43.8 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII91120.1 - 0.0039 16.0 1.2 0.0058 15.4 1.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KII91120.1 - 0.064 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Tannase PF07519.11 KII91121.1 - 2e-90 304.0 0.0 4.8e-88 296.1 0.0 2.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase La PF05383.17 KII91122.1 - 5.2e-17 61.6 0.0 8.1e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 La domain GRP PF07172.11 KII91122.1 - 1.6 9.4 11.0 5.3 7.8 11.0 1.9 1 0 0 1 1 1 0 Glycine rich protein family Peroxidase_2 PF01328.17 KII91123.1 - 0.024 15.2 0.0 0.027 15.0 0.0 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 IBR PF01485.21 KII91124.1 - 3.3e-17 62.5 31.3 6.3e-10 39.1 7.7 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KII91124.1 - 7e-05 22.6 6.1 7e-05 22.6 6.1 4.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII91124.1 - 0.00014 21.7 4.3 0.00014 21.7 4.3 4.3 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII91124.1 - 0.00035 20.4 3.9 0.00035 20.4 3.9 4.3 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII91124.1 - 0.017 15.3 8.2 0.017 15.3 8.2 3.9 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KII91124.1 - 0.021 14.9 7.6 0.021 14.9 7.6 3.4 3 1 0 3 3 3 0 RING-type zinc-finger Eapp_C PF10238.9 KII91124.1 - 2.9 8.0 20.7 0.067 13.3 1.7 3.3 3 0 0 3 3 3 0 E2F-associated phosphoprotein Cytomega_UL84 PF06284.11 KII91125.1 - 0.027 12.9 1.6 0.036 12.6 1.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ATP19 PF11022.8 KII91126.1 - 6.1e-26 90.6 0.3 6.8e-26 90.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit K G-alpha PF00503.20 KII91129.1 - 2.9e-98 329.3 0.0 3.4e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91129.1 - 4.5e-10 39.3 0.0 1.4e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.6 KII91129.1 - 0.0093 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 KII91129.1 - 0.014 15.6 0.0 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KII91129.1 - 0.019 14.3 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region YcgR PF07317.12 KII91130.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulator YcgR Arrestin_N PF00339.29 KII91132.1 - 0.004 17.2 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KII91132.1 - 0.037 14.5 0.0 2.7 8.4 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain AdoHcyase PF05221.17 KII91133.1 - 5.8e-133 442.6 0.0 1.2e-72 244.7 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KII91133.1 - 1.9e-82 275.1 0.5 2.9e-82 274.6 0.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII91133.1 - 5.4e-09 35.7 0.1 1e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KII91133.1 - 6.1e-05 22.6 0.2 9.7e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KII91133.1 - 0.0016 18.7 0.1 0.0039 17.4 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 KII91133.1 - 0.0034 17.8 0.2 0.011 16.2 0.2 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 KII91133.1 - 0.036 13.8 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.15 KII91133.1 - 0.051 13.7 0.1 0.83 9.8 0.2 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KII91133.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mitochondr_Som1 PF11093.8 KII91134.1 - 3.4e-09 36.6 0.1 4.2e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 MFS_1 PF07690.16 KII91137.1 - 5.3e-30 104.5 33.7 5.4e-29 101.2 34.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 KII91137.1 - 0.0045 16.7 1.3 0.009 15.7 1.3 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF1556 PF07590.11 KII91139.1 - 0.024 14.9 2.2 0.058 13.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) BCIP PF13862.6 KII91142.1 - 1.4e-48 165.4 0.0 1.8e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein AdoMet_MTase PF07757.13 KII91143.1 - 4.3e-32 110.8 0.0 4e-31 107.6 0.0 2.1 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KII91143.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII91143.1 - 0.088 13.5 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KII91143.1 - 0.091 12.7 0.7 0.69 9.9 0.7 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KII91143.1 - 0.097 13.4 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KII91143.1 - 0.21 11.4 0.9 0.38 10.5 0.9 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.27 KII91144.1 - 1.8e-56 188.1 0.5 4e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 KII91145.1 - 5.5e-59 200.1 0.0 6.3e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nab2 PF11517.8 KII91145.1 - 0.094 13.0 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) p450 PF00067.22 KII91146.1 - 4e-70 236.8 0.0 4.9e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pdase_M17_N2 PF18295.1 KII91148.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 RP-C_C PF11800.8 KII91151.1 - 0.1 12.7 3.8 0.1 12.7 3.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Spt20 PF12090.8 KII91151.1 - 0.86 9.2 9.5 0.87 9.2 9.5 1.1 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 KII91151.1 - 4.1 7.2 11.4 5.7 6.7 11.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus MKT1_C PF12246.8 KII91153.1 - 0.032 13.5 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication zf-C3HC4_3 PF13920.6 KII91154.1 - 7.8e-06 25.7 4.0 1.3e-05 25.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII91154.1 - 6e-05 22.8 5.5 9.6e-05 22.2 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII91154.1 - 0.00039 20.3 5.1 0.00062 19.7 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII91154.1 - 0.00066 19.5 7.6 0.0012 18.6 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_1 PF00076.22 KII91154.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 KII91154.1 - 0.058 13.4 2.5 0.07 13.2 1.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KII91154.1 - 0.23 11.8 5.9 0.42 11.0 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KII91154.1 - 0.25 11.2 4.7 0.73 9.7 4.9 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.12 KII91154.1 - 0.67 9.6 7.4 1.2 8.7 7.4 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Apolipoprotein PF01442.18 KII91155.1 - 1.1e-09 38.4 14.1 1.6e-09 37.9 14.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF885 PF05960.11 KII91155.1 - 0.00017 21.4 5.3 0.00021 21.1 5.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF3584 PF12128.8 KII91155.1 - 0.00069 17.3 13.2 0.00085 17.0 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) OmpH PF03938.14 KII91155.1 - 0.0017 18.7 17.4 0.0028 18.0 16.0 1.8 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Fez1 PF06818.15 KII91155.1 - 0.0019 18.7 12.6 0.0027 18.2 12.6 1.3 1 0 0 1 1 1 1 Fez1 DUF883 PF05957.13 KII91155.1 - 0.0021 18.6 14.0 0.39 11.3 6.4 2.8 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 KII91155.1 - 0.0028 17.3 5.1 0.0032 17.1 5.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit ApoLp-III PF07464.11 KII91155.1 - 0.0039 17.3 10.3 0.0067 16.5 10.1 1.5 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 KII91155.1 - 0.0042 17.6 8.5 0.0042 17.6 8.5 2.2 2 0 0 2 2 2 1 YtxH-like protein Fib_alpha PF08702.10 KII91155.1 - 0.0066 16.7 9.6 0.011 15.9 7.6 1.9 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KII91155.1 - 0.0068 15.3 14.9 0.0085 15.0 14.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Mer2 PF09074.10 KII91155.1 - 0.0071 16.2 5.2 0.0093 15.8 5.2 1.2 1 0 0 1 1 1 1 Mer2 FAM76 PF16046.5 KII91155.1 - 0.0098 15.3 6.7 0.013 14.8 6.7 1.3 1 0 0 1 1 1 1 FAM76 protein PKcGMP_CC PF16808.5 KII91155.1 - 0.012 15.5 1.9 0.012 15.5 1.9 4.0 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SKA2 PF16740.5 KII91155.1 - 0.015 15.1 8.9 0.029 14.1 4.6 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Baculo_PEP_C PF04513.12 KII91155.1 - 0.015 15.3 6.9 0.4 10.7 2.8 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mitofilin PF09731.9 KII91155.1 - 0.017 14.0 16.9 0.018 13.9 16.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1664 PF07889.12 KII91155.1 - 0.02 14.9 10.8 0.2 11.7 5.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 KII91155.1 - 0.024 14.0 9.5 0.031 13.6 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 KII91155.1 - 0.024 13.3 6.2 0.032 12.8 6.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF842 PF05811.13 KII91155.1 - 0.032 13.9 1.0 0.052 13.3 1.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) COG2 PF06148.11 KII91155.1 - 0.033 14.3 11.8 0.69 10.0 5.4 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 KII91155.1 - 0.039 11.9 1.9 0.044 11.8 1.9 1.2 1 0 0 1 1 1 0 Prominin Peptidase_C98 PF15499.6 KII91155.1 - 0.044 13.2 1.5 0.059 12.8 1.5 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ApoO PF09769.9 KII91155.1 - 0.053 13.5 1.3 0.17 11.9 1.2 1.9 1 1 0 1 1 1 0 Apolipoprotein O DUF16 PF01519.16 KII91155.1 - 0.082 13.4 12.1 1.2 9.7 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ribosomal_L22 PF00237.19 KII91155.1 - 0.091 13.0 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e Atg14 PF10186.9 KII91155.1 - 0.12 11.4 9.8 0.28 10.2 9.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Histidinol_dh PF00815.20 KII91155.1 - 0.12 11.3 4.6 0.16 10.9 4.6 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase FUSC PF04632.12 KII91155.1 - 0.13 10.7 4.8 0.16 10.5 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family THP2 PF09432.10 KII91155.1 - 0.14 12.2 5.0 0.31 11.1 4.4 1.9 1 1 1 2 2 2 0 Tho complex subunit THP2 ALMT PF11744.8 KII91155.1 - 0.14 11.0 3.1 0.16 10.8 3.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Phe_tRNA-synt_N PF02912.18 KII91155.1 - 0.15 12.0 18.4 0.65 10.0 3.0 3.6 1 1 3 4 4 4 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF3394 PF11874.8 KII91155.1 - 0.15 11.7 0.8 0.22 11.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) DUF2229 PF09989.9 KII91155.1 - 0.16 11.6 1.4 0.21 11.2 1.4 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PIN_8 PF18476.1 KII91155.1 - 0.16 11.8 9.5 0.12 12.2 6.6 1.5 1 1 1 2 2 2 0 PIN like domain NPV_P10 PF05531.12 KII91155.1 - 0.2 12.2 7.8 34 5.0 7.8 3.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FdhE PF04216.12 KII91155.1 - 0.21 11.4 3.6 0.26 11.1 3.6 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF1002 PF06207.11 KII91155.1 - 0.32 10.5 9.9 0.32 10.5 8.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) Terminase_2 PF03592.16 KII91155.1 - 0.35 11.3 7.9 0.48 10.9 7.9 1.2 1 0 0 1 1 1 0 Terminase small subunit ISG65-75 PF11727.8 KII91155.1 - 0.42 9.8 9.8 0.51 9.5 9.8 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein tRNA-synt_1c PF00749.21 KII91155.1 - 0.45 9.4 5.0 0.55 9.1 5.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Band_7_1 PF13421.6 KII91155.1 - 0.45 10.2 1.9 0.7 9.6 1.9 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Mre11_DNA_bind PF04152.14 KII91155.1 - 0.47 10.7 10.4 1.1 9.5 0.6 2.3 1 1 1 2 2 2 0 Mre11 DNA-binding presumed domain Bac_RepA_C PF18008.1 KII91155.1 - 0.53 10.7 3.4 0.56 10.6 0.6 2.1 1 1 1 2 2 2 0 Replication initiator protein A C-terminal domain ComFB PF10719.9 KII91155.1 - 0.55 10.4 4.8 6.9 6.8 0.8 2.5 1 1 1 2 2 2 0 Late competence development protein ComFB UPF0449 PF15136.6 KII91155.1 - 0.58 10.7 0.1 0.58 10.7 0.1 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 XLF PF09302.11 KII91155.1 - 0.6 10.3 6.8 1.8 8.7 0.1 2.5 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component AAA_13 PF13166.6 KII91155.1 - 0.6 8.7 12.2 0.47 9.0 7.2 1.6 1 1 1 2 2 2 0 AAA domain DIT1_PvcA PF05141.12 KII91155.1 - 0.63 9.4 6.5 1.2 8.6 6.5 1.5 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Adeno_terminal PF02459.15 KII91155.1 - 0.66 8.3 7.6 0.82 8.0 7.6 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Syntaxin-6_N PF09177.11 KII91155.1 - 0.7 10.5 13.1 1.6 9.3 5.1 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DctP PF03480.13 KII91155.1 - 0.72 9.1 6.8 0.88 8.9 3.8 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Baculo_p24 PF05073.12 KII91155.1 - 0.84 9.4 3.6 1.3 8.7 3.6 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein RRF PF01765.19 KII91155.1 - 0.85 9.6 16.2 0.19 11.6 10.3 2.0 1 1 1 2 2 2 0 Ribosome recycling factor DUF1512 PF07431.12 KII91155.1 - 0.96 8.4 5.9 3.4 6.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1512) AAA_32 PF13654.6 KII91155.1 - 1 8.1 12.1 1.6 7.4 12.1 1.4 1 1 0 1 1 1 0 AAA domain HMMR_N PF15905.5 KII91155.1 - 1 8.8 19.7 2.2 7.6 19.7 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HSP70 PF00012.20 KII91155.1 - 1.2 7.3 12.3 1.4 7.0 12.3 1.1 1 0 0 1 1 1 0 Hsp70 protein UPF0242 PF06785.11 KII91155.1 - 1.3 9.1 18.5 4.5 7.3 18.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 KII91155.1 - 1.3 6.8 5.8 1.5 6.6 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF848 PF05852.11 KII91155.1 - 1.5 9.0 18.5 0.13 12.3 11.4 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2937 PF11157.8 KII91155.1 - 1.6 8.4 3.5 0.95 9.2 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Vfa1 PF08432.10 KII91155.1 - 1.9 8.8 7.2 2.7 8.3 7.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.9 KII91155.1 - 2.2 6.7 10.7 2.7 6.5 10.7 1.1 1 0 0 1 1 1 0 Macoilin family Phage_Mu_Gam PF07352.12 KII91155.1 - 2.5 8.0 14.3 28 4.6 14.3 2.2 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein ECH_2 PF16113.5 KII91155.1 - 2.7 7.4 8.5 3.7 6.9 6.9 1.6 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase SICA_alpha PF12887.7 KII91155.1 - 2.9 7.7 8.0 47 3.8 8.0 2.3 1 1 0 1 1 1 0 SICA extracellular alpha domain dCache_2 PF08269.11 KII91155.1 - 3.2 6.9 9.3 5.2 6.2 9.3 1.4 1 1 0 1 1 1 0 Cache domain DUF2203 PF09969.9 KII91155.1 - 3.2 8.5 13.0 6.7 7.5 4.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ATP-synt_B PF00430.18 KII91155.1 - 3.2 7.8 20.3 6.8 6.8 19.9 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) CKAP2_C PF15297.6 KII91155.1 - 3.3 6.7 15.0 7.3 5.6 11.5 2.0 1 1 1 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus DLP_helical PF18709.1 KII91155.1 - 3.5 6.7 13.6 28 3.8 13.5 1.9 1 1 0 1 1 1 0 Dynamin-like helical domain LCIB_C_CA PF18599.1 KII91155.1 - 3.5 6.8 5.5 3.5 6.8 2.5 1.7 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1451 PF07295.11 KII91155.1 - 3.7 7.6 16.1 1.9 8.5 9.8 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain Spore_III_AB PF09548.10 KII91155.1 - 4.4 7.4 9.1 9.9 6.2 9.1 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HU-CCDC81_bac_2 PF18175.1 KII91155.1 - 4.5 7.2 6.2 26 4.8 1.5 2.8 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 RNase_J_C PF17770.1 KII91155.1 - 5.9 8.0 7.1 3.8 8.6 2.5 2.6 1 1 3 4 4 4 0 Ribonuclease J C-terminal domain COMPASS-Shg1 PF05205.12 KII91155.1 - 6 7.6 10.3 90 3.9 10.3 2.2 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 TMPIT PF07851.13 KII91155.1 - 6.1 6.0 8.3 14 4.8 8.3 1.7 1 1 0 1 1 1 0 TMPIT-like protein HisKA_3 PF07730.13 KII91155.1 - 6.8 7.3 13.3 28 5.3 1.7 3.2 1 1 1 2 2 2 0 Histidine kinase DUF5352 PF17303.2 KII91155.1 - 7.1 6.4 5.4 50 3.7 5.4 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5352) ATP11 PF06644.11 KII91155.1 - 8 6.2 10.9 18 5.0 8.2 2.1 1 1 1 2 2 2 0 ATP11 protein HSCB_C PF07743.13 KII91155.1 - 9.4 6.8 26.6 17 6.0 12.2 3.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain SNF2_N PF00176.23 KII91157.1 - 3.6e-62 210.1 0.7 2.4e-61 207.4 0.7 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII91157.1 - 1.4e-10 41.4 0.0 3.8e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KII91157.1 - 2.2e-10 40.4 5.2 3.4e-10 39.8 3.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII91157.1 - 1.4e-09 37.7 3.1 3.3e-09 36.5 3.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII91157.1 - 1.3e-08 34.6 7.0 2.8e-08 33.5 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII91157.1 - 3.7e-08 33.1 4.1 3.7e-08 33.1 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII91157.1 - 1.9e-07 31.1 5.3 8e-07 29.1 5.4 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII91157.1 - 3.1e-07 30.6 7.9 8.4e-07 29.2 7.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KII91157.1 - 3.6e-07 30.0 6.4 7.5e-07 29.0 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII91157.1 - 1.8e-06 27.7 5.8 1.5e-05 24.7 5.8 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 ResIII PF04851.15 KII91157.1 - 0.00014 22.0 0.1 0.00031 20.8 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Nse PF11789.8 KII91157.1 - 0.017 14.9 5.3 0.042 13.7 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Corona_S2 PF01601.16 KII91157.1 - 0.044 12.3 0.9 4.5 5.7 0.6 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein NOA36 PF06524.12 KII91157.1 - 0.098 12.0 7.1 0.24 10.7 7.1 1.7 1 0 0 1 1 1 0 NOA36 protein zf-rbx1 PF12678.7 KII91157.1 - 0.21 11.9 2.9 0.57 10.5 2.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KII91157.1 - 0.3 10.8 7.0 0.96 9.3 7.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KII91157.1 - 1.2 8.9 5.2 4.6 7.1 5.2 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SPT6_acidic PF14632.6 KII91157.1 - 9 7.0 31.2 0.39 11.3 21.0 3.2 3 0 0 3 3 3 0 Acidic N-terminal SPT6 RRF PF01765.19 KII91158.1 - 5.1e-26 91.5 0.2 7.3e-26 91.1 0.2 1.3 1 0 0 1 1 1 1 Ribosome recycling factor p450 PF00067.22 KII91159.1 - 3.1e-66 224.0 0.0 3.7e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KII91163.1 - 3.8e-39 134.2 2.0 5.1e-39 133.8 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91163.1 - 6.4e-29 101.2 0.8 7.7e-29 100.9 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91163.1 - 2.1e-07 31.0 0.4 2.9e-07 30.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII91163.1 - 3.6e-06 26.6 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KII91163.1 - 1.9e-05 24.2 0.1 0.014 14.7 0.0 2.7 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 KII91163.1 - 0.0017 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 KII91163.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Cas_Cas7 PF05107.12 KII91163.1 - 0.12 12.0 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 CRISPR-associated protein Cas7 PAE PF03283.13 KII91163.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase G-alpha PF00503.20 KII91164.1 - 1.5e-120 402.6 0.0 1.8e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91164.1 - 1.1e-10 41.3 0.1 5.3e-06 26.0 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 KII91164.1 - 0.0042 17.3 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KII91164.1 - 0.0057 16.1 0.1 0.0099 15.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 KII91164.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KII91164.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KII91164.1 - 0.048 12.9 0.4 0.12 11.6 0.1 1.8 1 1 1 2 2 2 0 Zeta toxin AAA_22 PF13401.6 KII91164.1 - 0.1 12.8 0.0 0.5 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KII91164.1 - 0.16 11.5 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FA_desaturase PF00487.24 KII91166.1 - 3.2e-15 56.7 27.8 5.4e-15 55.9 27.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII91166.1 - 3.1e-13 49.7 0.0 6.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2034 PF10356.9 KII91167.1 - 9.2e-20 70.8 0.0 2.1e-08 33.8 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KII91167.1 - 3.1e-06 27.2 0.0 6.8e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Restriction endonuclease ABC_membrane_2 PF06472.15 KII91168.1 - 3.6e-79 266.0 0.1 5.6e-79 265.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KII91168.1 - 7.2e-15 55.7 0.0 1.3e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KII91168.1 - 0.067 13.6 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 KII91168.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KII91168.1 - 0.081 12.5 0.5 0.5 9.9 0.1 2.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KII91168.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 KII91168.1 - 0.13 12.4 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 KII91168.1 - 0.18 12.1 0.2 0.74 10.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain Apolipoprotein PF01442.18 KII91169.1 - 5.6e-07 29.6 20.1 2.3e-06 27.6 20.1 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain OmpH PF03938.14 KII91169.1 - 0.00052 20.4 11.7 0.018 15.4 4.6 2.5 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) DUF883 PF05957.13 KII91169.1 - 0.00059 20.4 16.5 0.0086 16.7 4.0 3.1 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Fez1 PF06818.15 KII91169.1 - 0.00089 19.8 11.0 0.0014 19.1 10.5 1.5 1 1 0 1 1 1 1 Fez1 ATP-synt_B PF00430.18 KII91169.1 - 0.0019 18.3 6.9 0.0019 18.3 6.9 2.6 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Baculo_PEP_C PF04513.12 KII91169.1 - 0.0023 18.0 6.0 0.039 14.0 0.7 2.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 KII91169.1 - 0.0025 17.8 0.3 1.6 8.7 0.1 2.4 1 1 1 2 2 2 1 Apolipoprotein O ERM PF00769.19 KII91169.1 - 0.003 17.4 12.5 0.0047 16.8 12.5 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family CEP63 PF17045.5 KII91169.1 - 0.0034 17.3 9.7 0.011 15.7 8.5 1.9 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa Gp58 PF07902.11 KII91169.1 - 0.0036 15.7 4.4 0.0046 15.3 4.4 1.0 1 0 0 1 1 1 1 gp58-like protein Wtap PF17098.5 KII91169.1 - 0.008 16.1 7.4 1.4 8.9 0.2 3.0 1 1 1 2 2 2 2 WTAP/Mum2p family Fib_alpha PF08702.10 KII91169.1 - 0.0082 16.3 6.3 0.48 10.6 0.4 2.7 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KII91169.1 - 0.012 13.2 12.7 0.013 13.1 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HIP1_clath_bdg PF16515.5 KII91169.1 - 0.012 16.2 14.2 0.15 12.7 2.0 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TolA_bind_tri PF16331.5 KII91169.1 - 0.014 15.5 8.5 8.7 6.5 0.1 4.0 2 1 2 4 4 4 0 TolA binding protein trimerisation TMF_TATA_bd PF12325.8 KII91169.1 - 0.014 15.6 6.2 0.014 15.6 6.2 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YtxH PF12732.7 KII91169.1 - 0.015 15.8 11.3 0.49 11.0 5.4 2.7 2 1 0 2 2 2 0 YtxH-like protein DUF148 PF02520.17 KII91169.1 - 0.018 15.1 4.9 0.033 14.3 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1640 PF07798.11 KII91169.1 - 0.019 15.0 15.1 0.019 15.0 7.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) ApoLp-III PF07464.11 KII91169.1 - 0.023 14.8 6.8 0.85 9.7 3.2 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Golgin_A5 PF09787.9 KII91169.1 - 0.025 14.1 14.0 0.59 9.5 0.3 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF2884 PF11101.8 KII91169.1 - 0.026 14.1 6.2 0.56 9.7 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF4618 PF15397.6 KII91169.1 - 0.029 13.8 8.2 0.043 13.2 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HrpB7 PF09486.10 KII91169.1 - 0.044 14.2 20.3 0.48 10.8 7.6 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.12 KII91169.1 - 0.058 13.7 1.5 0.058 13.7 1.5 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KII91169.1 - 0.066 12.6 14.9 0.27 10.6 14.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KII91169.1 - 0.074 12.4 10.6 1.8 7.9 5.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spore_III_AB PF09548.10 KII91169.1 - 0.09 12.9 2.4 0.14 12.2 1.6 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Prominin PF05478.11 KII91169.1 - 0.11 10.4 3.7 0.15 10.0 3.7 1.2 1 0 0 1 1 1 0 Prominin YlqD PF11068.8 KII91169.1 - 0.14 12.5 5.1 0.19 12.1 0.3 2.2 1 1 1 2 2 2 0 YlqD protein Spc7 PF08317.11 KII91169.1 - 0.14 11.0 15.3 0.067 12.1 10.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 KII91169.1 - 0.18 11.3 12.9 0.24 10.8 8.0 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal T6PP_N PF18572.1 KII91169.1 - 0.19 11.5 6.4 0.05 13.4 1.0 2.2 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Muted PF14942.6 KII91169.1 - 0.21 11.9 8.2 0.35 11.2 1.8 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Lebercilin PF15619.6 KII91169.1 - 0.21 11.2 13.4 2.1 7.9 9.6 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 KII91169.1 - 0.28 11.0 7.0 0.18 11.7 1.5 3.3 2 1 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4449 PF14613.6 KII91169.1 - 0.32 11.1 6.1 0.45 10.6 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) HSP70 PF00012.20 KII91169.1 - 0.33 9.1 9.9 0.28 9.3 8.9 1.3 1 1 0 1 1 1 0 Hsp70 protein TetR_C_15 PF17918.1 KII91169.1 - 0.35 11.7 8.5 0.19 12.5 1.5 2.6 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Activator-TraM PF11657.8 KII91169.1 - 0.37 10.6 10.1 0.58 10.0 8.5 2.0 1 1 2 3 3 2 0 Transcriptional activator TraM DUF1664 PF07889.12 KII91169.1 - 0.39 10.8 10.9 3.2 7.8 2.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KII91169.1 - 0.39 11.0 6.1 1.7 9.0 1.2 3.0 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DLP_helical PF18709.1 KII91169.1 - 0.41 9.8 7.7 0.84 8.8 7.7 1.5 1 1 0 1 1 1 0 Dynamin-like helical domain Bacillus_HBL PF05791.11 KII91169.1 - 0.43 10.4 5.2 0.56 10.0 0.8 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.11 KII91169.1 - 0.43 10.9 7.1 8 6.8 1.2 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FUSC PF04632.12 KII91169.1 - 0.47 8.9 8.6 0.67 8.4 8.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPD52 PF04201.15 KII91169.1 - 0.61 9.7 9.8 0.077 12.6 0.5 2.6 1 1 2 3 3 3 0 Tumour protein D52 family FAM76 PF16046.5 KII91169.1 - 0.65 9.3 6.2 0.45 9.8 3.1 1.9 1 1 1 2 2 2 0 FAM76 protein WXG100 PF06013.12 KII91169.1 - 0.74 10.1 8.3 0.65 10.3 1.5 3.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DivIC PF04977.15 KII91169.1 - 0.8 9.5 10.6 1.3 8.9 3.0 3.4 2 1 2 4 4 4 0 Septum formation initiator PIN_8 PF18476.1 KII91169.1 - 0.9 9.3 8.2 1.9 8.3 4.3 2.0 1 1 1 2 2 2 0 PIN like domain TSNAXIP1_N PF15739.5 KII91169.1 - 0.91 9.9 11.5 4.7 7.6 1.0 3.0 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus Atg14 PF10186.9 KII91169.1 - 0.95 8.5 9.1 3.2 6.7 9.0 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YwqJ-deaminase PF14431.6 KII91169.1 - 0.97 9.6 4.0 2.7 8.2 3.1 2.1 1 1 1 2 2 2 0 YwqJ-like deaminase LPP PF04728.13 KII91169.1 - 0.98 9.9 8.7 2.4e+02 2.2 0.0 4.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper USP8_interact PF08941.10 KII91169.1 - 1.2 9.0 3.6 1.1 9.0 1.4 1.9 1 1 1 2 2 2 0 USP8 interacting TMPIT PF07851.13 KII91169.1 - 1.4 8.1 5.7 1.6 7.9 1.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein UPF0242 PF06785.11 KII91169.1 - 1.4 9.0 12.9 0.31 11.1 8.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KII91169.1 - 1.5 8.8 12.4 8.7 6.4 0.8 3.5 1 1 1 3 3 3 0 Prefoldin subunit ATG16 PF08614.11 KII91169.1 - 1.5 9.0 18.5 1.2 9.4 12.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GvpL_GvpF PF06386.11 KII91169.1 - 1.5 8.7 16.1 7.5 6.4 2.6 2.3 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF LCD1 PF09798.9 KII91169.1 - 1.7 7.0 7.9 26 3.1 7.9 2.1 1 1 0 1 1 1 0 DNA damage checkpoint protein Sirohm_synth_M PF14824.6 KII91169.1 - 2.1 7.9 7.0 9.2 5.8 0.0 4.1 5 0 0 5 5 5 0 Sirohaem biosynthesis protein central Csm1_N PF18504.1 KII91169.1 - 2.4 8.6 12.7 1.5 9.2 0.1 4.3 1 1 5 6 6 4 0 Csm1 N-terminal domain CENP-H PF05837.12 KII91169.1 - 2.5 8.6 12.5 12 6.4 0.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Syntaxin-6_N PF09177.11 KII91169.1 - 2.5 8.7 13.6 25 5.5 6.6 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.8 KII91169.1 - 2.5 8.1 13.9 4.1 7.5 0.6 3.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 KII91169.1 - 2.6 8.8 11.9 4.5 8.0 2.4 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) GrpE PF01025.19 KII91169.1 - 2.6 7.7 13.1 9.7 5.8 8.2 2.6 1 1 1 2 2 2 0 GrpE Phage_Mu_Gam PF07352.12 KII91169.1 - 3.1 7.7 10.8 13 5.7 1.4 2.8 1 1 2 3 3 3 0 Bacteriophage Mu Gam like protein HAUS6_N PF14661.6 KII91169.1 - 3.6 7.1 8.2 12 5.4 8.2 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HalX PF08663.10 KII91169.1 - 4.3 7.7 23.8 0.13 12.6 2.6 4.4 1 1 2 3 3 2 0 HalX domain Vps51 PF08700.11 KII91169.1 - 4.6 7.4 9.7 15 5.7 0.2 4.2 1 1 1 3 3 3 0 Vps51/Vps67 LCIB_C_CA PF18599.1 KII91169.1 - 5.4 6.2 8.2 5.3 6.3 1.2 2.3 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases LUC7 PF03194.15 KII91169.1 - 5.8 6.5 9.3 5.1 6.7 8.0 1.4 1 1 0 1 1 1 0 LUC7 N_terminus DUF724 PF05266.14 KII91169.1 - 7.7 6.3 10.1 3.4 7.5 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) RdRP PF05183.12 KII91170.1 - 9.3e-110 368.0 0.0 1.4e-109 367.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF5044 PF16447.5 KII91170.1 - 0.084 12.7 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5044) Glyco_hydro_28 PF00295.17 KII91171.1 - 6.4e-74 248.9 18.9 7.9e-74 248.6 18.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 KII91171.1 - 4.7e-06 26.0 6.3 7.5e-06 25.4 6.3 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 KII91171.1 - 2.5e-05 23.7 8.2 2.5e-05 23.7 8.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) Chlam_PMP PF02415.17 KII91171.1 - 2.8 8.6 16.6 2.2 8.9 0.0 5.3 6 2 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Chor_lyase PF04345.13 KII91172.1 - 0.22 11.2 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Chorismate lyase FA_desaturase PF00487.24 KII91173.1 - 2.8e-15 56.9 25.6 4.7e-15 56.1 25.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII91173.1 - 3.3e-13 49.6 0.0 7.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PhoR PF11808.8 KII91173.1 - 0.27 11.7 3.6 1.9 8.9 0.1 2.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Astro_capsid_N PF03115.14 KII91174.1 - 4.5e-05 22.3 0.0 4.7e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Astrovirus capsid protein precursor adh_short PF00106.25 KII91175.1 - 1e-27 96.9 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91175.1 - 2.3e-21 76.4 0.0 2.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91175.1 - 9.1e-09 35.5 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII91175.1 - 0.0011 18.8 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tran_WecB PF03808.13 KII91175.1 - 0.009 16.0 0.0 0.046 13.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family CRISPR_Cas2 PF09827.9 KII91177.1 - 0.00022 21.3 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 CRISPR associated protein Cas2 DUF2034 PF10356.9 KII91179.1 - 1.9e-16 60.0 0.2 4e-14 52.5 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KII91179.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease FA_desaturase PF00487.24 KII91180.1 - 4.3e-16 59.5 24.9 6.9e-16 58.8 24.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII91180.1 - 4.2e-13 49.2 0.0 9.1e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2034 PF10356.9 KII91181.1 - 3.4e-19 69.0 0.0 2.5e-15 56.4 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KII91181.1 - 3.9e-06 26.9 0.0 9.3e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease Tri3 PF07428.11 KII91183.1 - 0.0078 15.2 0.0 0.0098 14.8 0.0 1.0 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 Mlh1_C PF16413.5 KII91185.1 - 3.1e-92 308.8 0.0 6.7e-92 307.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KII91185.1 - 1.7e-27 95.4 0.0 3.1e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KII91185.1 - 1.4e-11 44.3 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KII91185.1 - 2.8e-07 31.0 0.0 5.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3245 PF11595.8 KII91185.1 - 3 8.3 5.9 20 5.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) MOR2-PAG1_N PF14222.6 KII91186.1 - 1.7e-163 545.6 0.0 2.4e-163 545.1 0.0 1.2 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KII91186.1 - 2.2e-86 289.8 0.5 2.3e-85 286.5 0.4 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KII91186.1 - 6.9e-20 70.4 0.0 3e-09 35.2 0.0 3.1 3 0 0 3 3 3 3 Cell morphogenesis central region Cyclin_N PF00134.23 KII91187.1 - 2.2e-47 159.9 1.7 3.1e-47 159.5 1.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KII91187.1 - 2.2e-28 98.7 0.0 4.8e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DSPc PF00782.20 KII91188.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII91188.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RPN1_RPN2_N PF17781.1 KII91189.1 - 2.3e-111 372.1 0.0 4.3e-111 371.2 0.0 1.4 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KII91189.1 - 6.4e-30 103.0 0.0 1.4e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KII91189.1 - 5.4e-25 86.5 16.1 0.00039 20.7 0.1 8.4 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KII91189.1 - 0.00017 21.9 0.1 1.1 9.7 0.1 3.7 4 0 0 4 4 4 2 HEAT repeats UPF0444 PF15475.6 KII91189.1 - 0.0079 16.4 0.3 1.3 9.4 0.1 2.7 2 0 0 2 2 2 1 Transmembrane protein C12orf23, UPF0444 DUF1039 PF06287.11 KII91189.1 - 0.052 14.0 0.8 6 7.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1039) CBS PF00571.28 KII91190.1 - 8.6e-08 32.5 0.0 0.00049 20.5 0.0 2.2 2 0 0 2 2 2 2 CBS domain HSP20 PF00011.21 KII91191.1 - 1.4e-13 50.9 0.0 1.1e-07 31.9 0.0 2.1 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII91191.1 - 5.9e-09 35.4 0.0 5.8e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA tRNA-synt_1 PF00133.22 KII91192.1 - 2.7e-151 504.8 0.0 3.7e-151 504.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KII91192.1 - 1e-21 77.5 0.1 1.8e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KII91192.1 - 9.6e-20 70.7 0.0 1.7e-13 50.1 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KII91192.1 - 0.0033 16.8 0.0 1.3 8.3 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 KII91192.1 - 0.19 11.6 7.0 0.65 9.9 7.0 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS ProRS-C_1 PF09180.11 KII91193.1 - 1.4e-26 92.4 0.2 3.1e-26 91.4 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KII91193.1 - 1.1e-17 64.6 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KII91193.1 - 1.3e-15 57.3 0.0 3.8e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.15 KII91193.1 - 1.5e-13 50.9 0.0 1.5e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain zf-ribbon_3 PF13248.6 KII91193.1 - 0.15 11.5 0.4 0.3 10.6 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain ProRS-C_1 PF09180.11 KII91194.1 - 4.2e-22 78.1 0.8 4.7e-22 78.0 0.8 1.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal zf-ribbon_3 PF13248.6 KII91194.1 - 0.0061 15.9 0.4 0.015 14.7 0.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KII91194.1 - 0.017 15.2 1.0 0.026 14.6 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain DJ-1_PfpI PF01965.24 KII91196.1 - 1.2e-37 129.2 0.0 1.5e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KII91196.1 - 0.0097 15.6 0.0 0.027 14.2 0.0 1.6 1 1 0 2 2 2 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KII91196.1 - 0.055 13.1 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain YAcAr PF10686.9 KII91196.1 - 0.14 12.1 0.0 0.61 10.1 0.0 1.9 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family APG6_N PF17675.1 KII91197.1 - 0.0028 18.2 17.6 0.014 15.9 3.1 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF4407 PF14362.6 KII91197.1 - 0.0051 16.2 6.1 0.0083 15.5 6.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) ATG16 PF08614.11 KII91197.1 - 0.0072 16.6 13.5 0.0072 16.6 13.5 3.3 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 KII91197.1 - 0.012 15.9 0.9 0.3 11.4 0.0 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 KII91197.1 - 0.015 15.4 23.3 0.085 12.9 5.3 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KII91197.1 - 0.028 14.5 6.2 0.18 11.8 1.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KII91197.1 - 0.062 11.8 6.8 0.098 11.2 6.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 KII91197.1 - 0.19 11.8 13.8 2.2 8.4 0.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KII91197.1 - 0.85 8.1 14.4 0.04 12.5 2.0 2.1 2 0 0 2 2 2 0 Macoilin family Phage_Nu1 PF07471.12 KII91197.1 - 1.1 9.1 8.2 1.8 8.3 8.2 1.3 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Fib_alpha PF08702.10 KII91197.1 - 1.6 8.9 4.6 2.4 8.3 0.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ATP-synt_D PF01813.17 KII91197.1 - 1.6 8.5 11.8 24 4.7 11.8 2.4 1 1 0 1 1 1 0 ATP synthase subunit D DUF4795 PF16043.5 KII91197.1 - 3.2 7.3 10.7 9.1 5.8 10.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 KII91197.1 - 3.7 7.7 10.3 7.8 6.6 0.1 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 KII91197.1 - 7.4 5.4 19.7 6.6 5.5 13.9 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein adh_short PF00106.25 KII91198.1 - 1e-29 103.4 0.0 9.8e-27 93.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91198.1 - 4e-17 62.6 0.0 6.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91198.1 - 1.4e-08 34.9 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII91198.1 - 0.00078 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KII91198.1 - 0.023 14.8 0.4 0.66 10.0 0.2 2.8 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KII91198.1 - 0.075 12.9 0.9 0.28 11.1 0.6 2.1 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KII91198.1 - 0.19 11.3 0.3 0.97 8.9 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family Glyco_hydro_18 PF00704.28 KII91199.1 - 1.1e-56 192.9 4.4 1.4e-56 192.6 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 KII91199.1 - 2.7e-14 53.1 0.0 4.2e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Cyt-b5 PF00173.28 KII91200.1 - 1.2e-19 70.2 0.0 2.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KII91200.1 - 6.3e-11 42.8 15.6 6.3e-11 42.8 15.6 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.28 KII91201.1 - 9.3e-89 297.9 0.0 1.2e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII91201.1 - 6.7e-10 39.8 0.1 1.9e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.6 KII91202.1 - 6.2e-18 65.7 0.1 2.2e-17 63.9 0.0 1.9 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91202.1 - 1.8e-11 44.4 0.0 3.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KII91203.1 - 1.6e-16 61.1 0.0 3.6e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91203.1 - 2.9e-12 47.0 0.0 5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 KII91204.1 - 3.1e-55 184.1 2.1 1.6e-21 76.0 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1430 PF07242.11 KII91206.1 - 0.84 9.9 10.3 0.06 13.6 1.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) His_Phos_2 PF00328.22 KII91207.1 - 9.8e-20 71.2 0.0 1.4e-18 67.4 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.12 KII91208.1 - 9.4e-32 109.2 3.6 1.7e-31 108.3 3.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII91208.1 - 8.8e-17 61.3 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII91208.1 - 8e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII91208.1 - 5e-06 27.6 0.0 8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KII91208.1 - 0.00058 19.2 0.9 0.00083 18.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KII91208.1 - 0.004 15.9 0.0 0.005 15.5 0.0 1.1 1 0 0 1 1 1 1 Staphylopine dehydrogenase Sacchrp_dh_NADP PF03435.18 KII91208.1 - 0.0047 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KII91208.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3395 PF11875.8 KII91209.1 - 8.3e-08 32.3 0.1 2.7e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) Gti1_Pac2 PF09729.9 KII91210.1 - 7.5e-27 94.6 1.2 3.2e-24 86.0 0.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family CENP_C_N PF15622.6 KII91210.1 - 0.071 12.6 1.0 0.13 11.7 1.0 1.4 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal DUF155 PF02582.14 KII91211.1 - 1.7e-53 181.3 0.3 3.2e-53 180.4 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CorA PF01544.18 KII91211.1 - 0.11 11.8 2.5 0.084 12.2 0.6 1.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Sec5 PF15469.6 KII91212.1 - 2.1e-60 203.8 2.1 2.2e-60 203.8 0.1 2.1 3 0 0 3 3 3 1 Exocyst complex component Sec5 RunxI PF08504.11 KII91212.1 - 0.0095 16.6 0.0 0.69 10.7 0.0 3.0 2 0 0 2 2 2 1 Runx inhibition domain Sec15 PF04091.12 KII91212.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Vps51 PF08700.11 KII91212.1 - 0.12 12.5 0.0 0.47 10.6 0.0 2.1 1 0 0 1 1 1 0 Vps51/Vps67 HhH-GPD PF00730.25 KII91213.1 - 8.1e-20 71.3 0.0 2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KII91213.1 - 5.4e-10 39.2 0.0 7.6e-09 35.5 0.0 2.7 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 KII91213.1 - 0.00045 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 KII91213.1 - 0.044 14.1 3.3 0.094 13.1 3.3 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III TauD PF02668.16 KII91214.1 - 5.5e-47 160.8 0.1 7.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KII91215.1 - 5.8e-21 74.8 16.0 5.8e-21 74.8 16.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4500 PF14937.6 KII91215.1 - 0.044 13.8 0.3 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) Peptidase_M10 PF00413.24 KII91215.1 - 0.058 13.2 0.0 0.097 12.5 0.0 1.5 1 1 0 1 1 1 0 Matrixin SURF4 PF02077.15 KII91216.1 - 1.4e-93 313.4 2.8 1.6e-93 313.2 2.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 KII91216.1 - 0.00035 20.6 0.5 0.0052 16.8 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5562) Lactonase PF10282.9 KII91217.1 - 1.1e-21 77.6 0.0 1.8e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KII91217.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Corona_NS4 PF03905.13 KII91217.1 - 0.62 10.1 3.9 7.8 6.6 0.2 2.6 2 0 0 2 2 2 0 Coronavirus non-structural protein NS4 adh_short PF00106.25 KII91218.1 - 5.6e-20 71.6 0.0 2.8e-13 49.8 0.2 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91218.1 - 1.7e-08 34.3 0.0 9.3e-05 22.1 0.1 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91218.1 - 0.0001 22.3 0.2 0.00016 21.7 0.2 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KII91218.1 - 0.16 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Treacle PF03546.14 KII91219.1 - 0.0023 16.8 4.1 0.0035 16.2 4.1 1.2 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle AF-4 PF05110.13 KII91219.1 - 0.014 13.5 6.4 0.018 13.1 6.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF5531 PF17671.1 KII91220.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5531) AMP-binding PF00501.28 KII91221.1 - 1.3e-66 225.0 0.0 1.8e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KII91221.1 - 3.3e-65 219.8 0.0 6.2e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KII91221.1 - 2.4e-12 47.0 0.0 1.1e-11 44.9 0.0 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 KII91221.1 - 1.8e-11 43.4 0.0 9.7e-11 41.0 0.0 2.0 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 KII91221.1 - 3.2e-07 30.0 0.0 6.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KII91221.1 - 1.4e-05 26.0 0.0 9.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NUC153 PF08159.12 KII91223.1 - 5.9e-11 42.0 0.3 1.2e-10 41.0 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KII91223.1 - 0.0037 18.1 0.1 8.6 7.4 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF295 PF03478.18 KII91224.1 - 0.12 12.0 0.1 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF295) adh_short PF00106.25 KII91225.1 - 2e-29 102.5 0.0 4.7e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91225.1 - 6.7e-17 61.8 0.0 1.5e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91225.1 - 2.3e-07 30.9 0.2 3.4e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII91225.1 - 0.0042 16.6 0.1 0.0067 15.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII91225.1 - 0.025 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KII91225.1 - 0.15 11.9 0.5 0.63 9.9 0.4 1.9 1 1 1 2 2 2 0 NAD(P)H-binding Lactonase PF10282.9 KII91226.1 - 1.8e-28 99.8 0.0 2.5e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KII91226.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Abhydrolase_1 PF00561.20 KII91227.1 - 5.2e-19 68.9 0.1 8.8e-17 61.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII91227.1 - 2.5e-16 60.9 3.2 3.4e-16 60.5 3.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII91227.1 - 2e-08 33.8 0.1 3e-08 33.2 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KII91227.1 - 2.1e-08 33.2 0.0 2.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 KII91227.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KII91227.1 - 0.07 13.0 0.2 0.26 11.1 0.1 1.9 1 1 1 2 2 2 0 Serine hydrolase Dioxygenase_C PF00775.21 KII91228.1 - 2.4e-41 141.1 0.0 3.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KII91228.1 - 2.1e-26 91.5 0.1 3.2e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KII91228.1 - 3.3e-05 24.1 0.0 9.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ADH_N PF08240.12 KII91229.1 - 2.8e-33 114.1 4.7 5.2e-33 113.2 4.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII91229.1 - 2e-16 60.1 0.0 3.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII91229.1 - 7.7e-13 48.4 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII91229.1 - 2.5e-08 35.0 0.0 7.5e-08 33.5 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KII91229.1 - 0.00017 21.0 0.6 0.00025 20.4 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain MAF_flag10 PF01973.18 KII91229.1 - 0.048 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 ADH_N_assoc PF13823.6 KII91229.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.20 KII91229.1 - 0.11 12.6 0.2 0.41 10.7 0.2 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KH_1 PF00013.29 KII91230.1 - 3.3e-06 26.8 0.1 9.9e-06 25.3 0.1 1.8 1 0 0 1 1 1 1 KH domain CAP_N PF01213.19 KII91230.1 - 2.6 7.4 25.1 0.36 10.3 7.6 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Oxidored_FMN PF00724.20 KII91231.1 - 2e-75 254.2 0.0 2.4e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase_Tyr PF07714.17 KII91233.1 - 5.7e-41 140.5 0.0 7.5e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII91233.1 - 1.5e-36 126.1 0.0 1.8e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII91233.1 - 0.002 17.5 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KII91233.1 - 0.0032 17.1 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KII91233.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII91233.1 - 0.06 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NitrOD5 PF11537.8 KII91234.1 - 0.00076 19.6 0.2 0.0038 17.3 0.1 2.1 3 0 0 3 3 3 1 Nitrosopumilus output domain 5 Apt1 PF10351.9 KII91234.1 - 0.011 14.6 3.1 0.011 14.6 3.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KII91234.1 - 0.02 13.5 3.4 0.023 13.3 3.4 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 KII91234.1 - 0.048 12.9 7.6 0.072 12.3 7.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 KII91234.1 - 0.068 11.9 5.2 0.08 11.6 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.9 KII91234.1 - 0.093 12.3 17.8 0.17 11.5 17.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 KII91234.1 - 0.15 10.5 7.9 0.19 10.1 7.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF5427 PF10310.9 KII91234.1 - 0.31 9.9 8.4 0.47 9.4 8.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RAP1 PF07218.11 KII91234.1 - 4.5 5.4 10.1 6 5.0 10.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rrn6 PF10214.9 KII91234.1 - 4.9 5.5 16.7 6.5 5.1 16.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BCNT PF07572.12 KII91235.1 - 1.1e-19 70.3 0.0 2e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development Peptidase_M36 PF02128.15 KII91236.1 - 3e-143 477.5 9.8 4.2e-143 477.0 9.8 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KII91236.1 - 7.3e-06 25.7 2.1 1.3e-05 25.0 0.1 2.5 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif SRP19 PF01922.17 KII91237.1 - 1.3e-26 93.4 0.0 2.1e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein PAXIP1_C PF15364.6 KII91237.1 - 0.065 13.5 0.3 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Pex14_N PF04695.13 KII91237.1 - 0.11 13.2 7.7 0.96 10.1 2.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CCDC53 PF10152.9 KII91237.1 - 0.82 10.1 3.6 1.8 8.9 0.5 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex JTB PF05439.12 KII91238.1 - 2.5e-05 24.3 0.1 2.5e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) COesterase PF00135.28 KII91240.1 - 1.7e-35 122.9 0.0 1.3e-33 116.7 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family DUF1749 PF08538.10 KII91240.1 - 0.0033 16.6 0.0 0.0049 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 KII91240.1 - 0.0037 17.2 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold SHMT PF00464.19 KII91241.1 - 6.5e-167 555.2 0.0 7.6e-167 554.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KII91241.1 - 0.0061 15.9 0.1 0.017 14.4 0.1 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Nop14 PF04147.12 KII91242.1 - 0.13 10.4 4.4 0.19 9.9 4.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KII91242.1 - 0.8 9.1 5.5 1.2 8.5 5.5 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 KII91242.1 - 4.1 6.6 12.1 6.3 6.0 12.1 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4336 PF14234.6 KII91243.1 - 6.4e-10 38.7 0.1 0.0033 16.7 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4336) Cu-oxidase PF00394.22 KII91245.1 - 4.6e-38 130.8 0.1 3.9e-36 124.6 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KII91245.1 - 2.8e-37 127.5 0.2 4.5e-33 113.9 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KII91245.1 - 3.2e-33 114.2 0.3 2.3e-31 108.3 0.1 3.6 4 1 1 5 5 5 1 Multicopper oxidase HVSL PF09749.9 KII91245.1 - 0.22 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein Gly-zipper_Omp PF13488.6 KII91245.1 - 1.9 8.5 5.3 5 7.2 5.3 1.7 1 0 0 1 1 1 0 Glycine zipper FTR1 PF03239.14 KII91246.1 - 1.7e-64 217.9 7.9 2e-64 217.7 7.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family S_4TM PF18159.1 KII91246.1 - 5.2 6.3 9.8 5.5 6.2 0.8 3.0 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain F-box-like PF12937.7 KII91247.1 - 2e-07 30.8 0.2 2e-07 30.8 0.2 2.9 3 1 1 4 4 4 1 F-box-like F-box-like PF12937.7 KII91249.1 - 1.3e-05 24.9 0.8 1.3e-05 24.9 0.8 2.4 1 1 1 2 2 2 1 F-box-like Wza_C PF18412.1 KII91250.1 - 0.069 12.9 0.0 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain CDC45 PF02724.14 KII91251.1 - 0.61 8.3 3.2 0.83 7.9 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KII91251.1 - 0.88 8.4 6.9 1.4 7.7 6.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KII91251.1 - 1.5 7.3 2.9 2.2 6.8 2.9 1.2 1 0 0 1 1 1 0 Macoilin family DNA_pol_phi PF04931.13 KII91251.1 - 2.5 6.1 8.4 3.6 5.6 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4614 PF15391.6 KII91251.1 - 3.3 7.7 13.2 15 5.5 11.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) BUD22 PF09073.10 KII91251.1 - 7.2 5.8 17.8 0.016 14.6 6.8 1.8 2 0 0 2 2 2 0 BUD22 DAP3 PF10236.9 KII91252.1 - 6.7e-61 206.2 0.0 8.6e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KII91252.1 - 2.4e-05 24.8 0.0 4.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 KII91252.1 - 0.0024 16.9 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 KII91252.1 - 0.0035 17.3 0.0 0.0096 15.9 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KII91252.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KII91252.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 KII91252.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KII91252.1 - 0.033 14.5 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KII91252.1 - 0.051 13.1 0.1 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KII91252.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KII91252.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 KII91252.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KII91252.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII91252.1 - 0.16 12.5 0.0 0.44 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KII91252.1 - 0.18 12.2 0.0 0.37 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 KII91253.1 - 1.4e-67 227.8 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91253.1 - 4.2e-29 101.6 0.0 5.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII91253.1 - 4.2e-05 22.7 0.0 5.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII91253.1 - 0.026 14.5 0.0 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KII91253.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Tcf25 PF04910.14 KII91253.1 - 0.26 10.3 0.0 0.72 8.9 0.0 1.5 1 1 1 2 2 2 0 Transcriptional repressor TCF25 NUDIX PF00293.28 KII91254.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain rve PF00665.26 KII91255.1 - 0.00094 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain CBFD_NFYB_HMF PF00808.23 KII91258.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DAO PF01266.24 KII91260.1 - 9.7e-28 97.7 0.9 1.4e-27 97.2 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribosomal_S26e PF01283.19 KII91261.1 - 3.3e-53 178.7 7.5 4e-53 178.4 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KII91261.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain DUF1918 PF08940.11 KII91261.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) BACON PF13004.7 KII91262.1 - 8.9 6.4 17.8 2.1 8.4 14.0 2.1 2 1 0 2 2 2 0 Putative binding domain, N-terminal zf-PARP PF00645.18 KII91263.1 - 2.8e-24 85.8 0.0 3.4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region YqfQ PF14181.6 KII91264.1 - 3.4 7.9 10.9 3.7 7.7 10.9 1.0 1 0 0 1 1 1 0 YqfQ-like protein zf-met PF12874.7 KII91265.1 - 6.3e-10 39.1 13.8 0.00083 19.7 0.1 4.7 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C3HC4_3 PF13920.6 KII91265.1 - 7.6e-10 38.5 6.9 7.6e-10 38.5 6.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.8 KII91265.1 - 3.7e-09 36.6 7.7 0.012 15.9 0.1 4.3 4 0 0 4 4 3 3 Zinc-finger double-stranded RNA-binding zf-RING_2 PF13639.6 KII91265.1 - 1.2e-07 32.0 10.5 1.2e-07 32.0 10.5 3.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII91265.1 - 2.8e-06 27.1 11.6 2.8e-06 27.1 11.6 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII91265.1 - 4.6e-06 26.4 22.3 1.2e-05 25.1 10.6 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII91265.1 - 1.2e-05 25.2 9.7 1.2e-05 25.2 9.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KII91265.1 - 1.5e-05 25.2 4.9 1.5e-05 25.2 4.9 3.2 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KII91265.1 - 9.2e-05 22.4 6.8 9.2e-05 22.4 6.8 4.0 4 1 0 4 4 4 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KII91265.1 - 0.00062 19.8 4.2 0.00062 19.8 4.2 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KII91265.1 - 0.0064 16.6 11.7 0.0064 16.6 11.7 3.4 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C2H2_2 PF12756.7 KII91265.1 - 0.011 16.0 2.0 0.037 14.3 1.1 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_4 PF14570.6 KII91265.1 - 0.014 15.2 3.6 0.014 15.2 3.6 2.6 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KII91265.1 - 0.022 14.6 7.7 0.022 14.6 7.7 2.4 2 1 1 3 3 2 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 KII91265.1 - 0.023 15.1 0.2 0.091 13.3 0.1 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type TerY_C PF15616.6 KII91265.1 - 0.027 14.6 4.0 0.32 11.1 1.2 2.3 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C2H2_6 PF13912.6 KII91265.1 - 0.15 12.1 0.3 0.15 12.1 0.3 4.9 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KII91265.1 - 0.48 11.4 0.1 0.48 11.4 0.1 6.4 6 1 1 7 7 5 0 C2H2-type zinc finger Prok-RING_4 PF14447.6 KII91265.1 - 0.66 9.9 22.8 0.042 13.7 11.7 3.5 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KII91265.1 - 2.7 8.2 19.1 13 6.0 3.6 3.5 2 2 0 2 2 2 0 FYVE zinc finger MFS_1 PF07690.16 KII91266.1 - 3.1e-19 69.1 16.7 4e-19 68.7 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 KII91266.1 - 0.051 13.9 3.8 1.1 9.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) HEAT PF02985.22 KII91267.1 - 1.6e-05 24.8 0.4 22 5.6 0.1 6.4 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 KII91267.1 - 6.1e-05 23.3 4.5 0.68 10.4 0.1 6.0 5 2 3 8 8 8 2 HEAT repeats DUF4600 PF15372.6 KII91267.1 - 0.0044 17.5 2.2 0.019 15.4 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) UNC45-central PF11701.8 KII91267.1 - 0.065 13.2 0.4 0.83 9.6 0.1 3.0 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central HEPN-like_int PF18867.1 KII91267.1 - 0.14 12.1 0.0 0.53 10.2 0.0 2.0 1 0 0 1 1 1 0 HEPN-like integron domain HEAT_EZ PF13513.6 KII91267.1 - 0.16 12.5 1.8 33 5.1 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat ORC6 PF05460.13 KII91267.1 - 1.4 8.2 12.5 2.3 7.4 12.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cwf_Cwc_15 PF04889.12 KII91267.1 - 2.8 7.6 20.4 5.2 6.7 20.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 KII91267.1 - 2.9 5.9 10.5 7.1 4.6 10.5 1.6 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KII91267.1 - 5.1 7.5 11.7 15 6.0 11.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NARP1 PF12569.8 KII91268.1 - 1e-160 536.1 3.3 3.8e-159 530.9 0.5 2.4 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 KII91268.1 - 3.3e-13 48.7 16.8 0.0027 17.7 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII91268.1 - 7e-12 45.1 13.8 0.54 11.2 0.1 9.9 7 2 4 11 11 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII91268.1 - 1.4e-10 41.5 11.2 0.084 13.4 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KII91268.1 - 8.9e-09 34.8 6.1 0.0018 18.0 0.4 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII91268.1 - 7.6e-08 32.0 10.5 0.0064 16.6 0.1 6.0 7 0 0 7 7 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII91268.1 - 2.2e-07 31.0 1.0 0.00092 19.4 0.0 4.7 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KII91268.1 - 4.2e-07 29.6 1.5 0.00012 21.7 0.3 4.7 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 KII91268.1 - 2.7e-06 27.4 4.5 0.35 11.0 0.3 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KII91268.1 - 5.2e-05 23.3 0.3 12 6.5 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII91268.1 - 5.6e-05 23.7 21.2 0.22 12.2 0.1 8.1 7 2 2 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KII91268.1 - 0.0015 18.4 2.8 0.1 12.7 0.0 4.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII91268.1 - 0.002 18.4 12.9 0.36 11.1 0.0 6.3 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII91268.1 - 0.019 14.8 0.9 22 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII91268.1 - 0.042 14.5 13.2 6.8 7.6 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat OAS1_C PF10421.9 KII91269.1 - 0.14 11.6 0.0 0.36 10.3 0.2 1.5 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus HLH PF00010.26 KII91270.1 - 3.7e-12 46.0 0.0 8.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.6 KII91270.1 - 0.0036 17.5 4.3 0.021 15.0 3.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) YL1 PF05764.13 KII91270.1 - 0.0043 17.2 5.4 0.0043 17.2 5.4 2.0 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 KII91270.1 - 0.0093 14.3 2.3 0.015 13.7 2.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.13 KII91270.1 - 0.38 10.6 5.6 0.15 12.0 2.8 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 KII91270.1 - 0.64 8.2 4.3 0.94 7.6 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family AT_hook PF02178.19 KII91270.1 - 0.76 9.9 11.2 0.43 10.6 7.7 2.6 2 0 0 2 2 2 0 AT hook motif DNA_pol_phi PF04931.13 KII91270.1 - 1.1 7.3 4.1 1.8 6.6 4.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi FA_desaturase PF00487.24 KII91271.1 - 5.3e-23 82.1 13.3 7.9e-23 81.6 13.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KII91271.1 - 1e-18 66.5 0.2 1.7e-18 65.8 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Acetyltransf_3 PF13302.7 KII91272.1 - 6.8e-09 36.5 0.1 1.6e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII91272.1 - 9.7e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4336 PF14234.6 KII91274.1 - 7.4e-12 45.1 0.0 0.0014 17.9 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Hira PF07569.11 KII91275.1 - 3.2e-56 190.5 0.0 5.8e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KII91275.1 - 6.3e-29 99.6 18.0 1.8e-05 25.4 0.3 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91275.1 - 2.4e-12 47.0 1.1 0.45 10.8 0.0 7.1 3 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KII91275.1 - 0.079 12.3 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region HIRA_B PF09453.10 KII91275.1 - 0.14 12.1 1.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 HIRA B motif MFS_1 PF07690.16 KII91276.1 - 7.2e-19 67.9 16.4 1e-18 67.5 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SfLAP PF11139.8 KII91276.1 - 0.00075 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein MFS_1 PF07690.16 KII91277.1 - 1.5e-20 73.4 11.8 2.1e-20 72.9 11.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 KII91277.1 - 0.003 16.2 0.9 0.0059 15.3 0.9 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SfLAP PF11139.8 KII91277.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein 60KD_IMP PF02096.20 KII91277.1 - 0.099 12.5 2.1 3 7.7 0.4 2.4 2 0 0 2 2 2 0 60Kd inner membrane protein Prenyltrans PF00432.21 KII91278.1 - 0.073 12.8 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Ribosomal_L44 PF00935.19 KII91279.1 - 3.2e-37 126.8 12.2 5.1e-37 126.2 12.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 KII91279.1 - 0.012 15.9 0.9 0.021 15.1 0.9 1.4 1 0 0 1 1 1 0 Cathelicidin HMG-CoA_red PF00368.18 KII91280.1 - 2.6e-140 467.6 6.0 3.6e-140 467.1 6.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 KII91280.1 - 1.2e-14 54.4 0.0 3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KII91280.1 - 0.046 11.8 0.0 0.066 11.3 0.0 1.2 1 0 0 1 1 1 0 Patched family DUF647 PF04884.14 KII91281.1 - 4.2e-79 265.6 1.3 6e-79 265.1 1.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis F-box-like PF12937.7 KII91282.1 - 2.4e-06 27.4 1.2 1e-05 25.3 0.2 2.7 2 0 0 2 2 2 1 F-box-like S1-P1_nuclease PF02265.16 KII91283.1 - 4.6e-45 154.4 0.0 2.4e-41 142.3 0.0 2.8 3 0 0 3 3 3 2 S1/P1 Nuclease DUF4949 PF16307.5 KII91283.1 - 0.046 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) Methyltransf_16 PF10294.9 KII91284.1 - 4.9e-09 36.2 0.0 8.6e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KII91284.1 - 0.012 15.5 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KII91284.1 - 0.13 12.1 0.0 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Metallophos PF00149.28 KII91285.1 - 2.6e-36 126.1 0.1 4.1e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4653 PF15546.6 KII91285.1 - 0.23 11.0 3.8 0.41 10.2 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) UNC-50 PF05216.13 KII91286.1 - 1.9e-85 285.9 14.1 2.1e-85 285.8 14.1 1.0 1 0 0 1 1 1 1 UNC-50 family WW PF00397.26 KII91287.1 - 5e-07 29.7 1.0 9.9e-07 28.7 1.0 1.5 1 0 0 1 1 1 1 WW domain TFIIF_alpha PF05793.12 KII91287.1 - 0.26 9.8 6.5 0.32 9.5 5.7 1.6 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4646 PF15496.6 KII91289.1 - 5.9e-22 78.6 0.3 1e-21 77.8 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) IMUP PF15761.5 KII91289.1 - 0.0076 16.9 2.5 0.0076 16.9 2.5 1.6 2 0 0 2 2 2 1 Immortalisation up-regulated protein Dehydrin PF00257.19 KII91289.1 - 0.016 15.8 0.9 0.021 15.4 0.9 1.3 1 0 0 1 1 1 0 Dehydrin LegC3_N PF18654.1 KII91289.1 - 0.027 13.7 7.9 0.034 13.4 7.9 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain Sin3a_C PF16879.5 KII91290.1 - 2.9e-76 256.9 0.0 1.2e-74 251.6 0.0 3.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KII91290.1 - 7.7e-41 138.1 0.2 2.2e-40 136.7 0.2 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KII91290.1 - 2.7e-31 107.4 6.7 5.4e-17 61.7 0.0 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat YcaO_C PF18381.1 KII91290.1 - 0.024 14.6 0.1 0.073 13.0 0.1 1.8 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Aldedh PF00171.22 KII91291.1 - 1.9e-123 412.4 5.6 2.4e-123 412.1 5.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KII91291.1 - 1.9e-05 23.9 2.7 0.00026 20.2 0.6 2.1 1 1 1 2 2 2 2 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KII91291.1 - 0.011 15.2 0.0 0.052 13.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF4646 PF15496.6 KII91292.1 - 4.5e-20 72.5 0.0 7.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 KII91292.1 - 0.0073 16.4 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family LprI PF07007.12 KII91292.1 - 0.054 14.2 2.7 0.12 13.0 2.7 1.5 1 0 0 1 1 1 0 Lysozyme inhibitor LprI Mg_trans_NIPA PF05653.14 KII91293.1 - 1.7e-96 322.8 13.4 2.1e-96 322.5 13.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KII91293.1 - 0.0047 17.1 26.5 0.012 15.8 4.1 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF5480 PF17576.2 KII91293.1 - 1.6 8.8 7.0 8.8 6.4 0.0 4.1 3 1 1 4 4 4 0 Family of unknown function (DUF5480) AAA_12 PF13087.6 KII91294.1 - 1.5e-43 148.8 0.0 2.3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII91294.1 - 3.1e-29 102.5 0.0 6.6e-14 52.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KII91294.1 - 2.8e-14 53.3 0.0 8.3e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KII91294.1 - 5.3e-10 39.8 0.0 3.6e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KII91294.1 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KII91294.1 - 9.8e-06 25.3 0.0 0.0098 15.4 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KII91294.1 - 0.00057 19.4 0.1 0.0068 15.9 0.0 2.4 2 1 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KII91294.1 - 0.0018 18.6 0.0 0.0058 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII91294.1 - 0.0063 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KII91294.1 - 0.0095 15.8 0.2 0.044 13.6 0.2 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 KII91294.1 - 0.041 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.14 KII91294.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KII91294.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KII91294.1 - 0.097 12.2 0.1 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 KII91294.1 - 0.11 13.0 0.0 0.39 11.2 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KII91295.1 - 1.6e-43 148.3 0.0 2.8e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII91295.1 - 1.7e-10 40.5 0.0 3.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KII91295.1 - 4.3e-08 33.5 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KII91295.1 - 1.1e-06 28.5 0.3 2.4e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KII91295.1 - 1.8e-06 28.0 0.0 7.1e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII91295.1 - 7.6e-06 26.4 0.1 8.2e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KII91295.1 - 3.1e-05 24.3 0.4 0.0061 16.8 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KII91295.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KII91295.1 - 0.00054 20.5 0.1 0.021 15.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 KII91295.1 - 0.00097 18.4 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KII91295.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KII91295.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KII91295.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KII91295.1 - 0.0084 15.6 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KII91295.1 - 0.0086 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KII91295.1 - 0.0099 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KII91295.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KII91295.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KII91295.1 - 0.021 14.6 0.0 0.098 12.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KII91295.1 - 0.023 14.4 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 KII91295.1 - 0.024 14.9 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_7 PF12775.7 KII91295.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KII91295.1 - 0.027 13.6 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KII91295.1 - 0.034 14.2 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII91295.1 - 0.041 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DivIC PF04977.15 KII91295.1 - 0.056 13.2 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator Parvo_NS1 PF01057.17 KII91295.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.6 KII91295.1 - 0.062 12.0 0.4 2.7 6.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KII91295.1 - 0.073 13.4 0.0 0.58 10.5 0.1 2.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KII91295.1 - 0.073 12.6 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KII91295.1 - 0.096 11.9 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF5406 PF17400.2 KII91295.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5406) NACHT PF05729.12 KII91295.1 - 0.13 12.1 0.0 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.6 KII91295.1 - 0.16 11.8 0.4 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 KII91296.1 - 3.1e-44 151.0 0.0 5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII91296.1 - 1.4e-30 107.0 0.0 1.4e-14 54.5 0.0 2.8 2 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KII91296.1 - 2.7e-14 53.3 0.0 1.5e-13 50.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KII91296.1 - 1.1e-13 51.8 0.0 1.2e-12 48.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain UvrD-helicase PF00580.21 KII91296.1 - 0.00017 21.3 0.0 0.0051 16.4 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KII91296.1 - 0.00082 18.9 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 KII91296.1 - 0.0024 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KII91296.1 - 0.0041 17.5 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KII91296.1 - 0.014 15.6 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KII91296.1 - 0.017 14.9 0.0 26 4.4 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KII91296.1 - 0.03 14.1 0.4 0.14 12.0 0.4 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KII91296.1 - 0.057 13.8 0.1 0.4 11.1 0.1 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KII91296.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KII91296.1 - 0.075 13.5 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KII91296.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Helicase DEAD PF00270.29 KII91296.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C PF13361.6 KII91296.1 - 0.2 11.0 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SKG6 PF08693.10 KII91297.1 - 0.4 10.1 5.8 0.95 8.9 5.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pribosyltran PF00156.27 KII91301.1 - 7.5e-13 48.3 0.1 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain G-alpha PF00503.20 KII91302.1 - 1.8e-132 441.8 0.0 2.2e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91302.1 - 6.5e-08 32.2 0.1 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KII91302.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KII91302.1 - 0.011 15.4 0.0 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KII91302.1 - 0.012 14.9 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KII91302.1 - 0.078 13.4 0.3 0.17 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 KII91302.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KII91302.1 - 0.15 12.6 0.0 0.6 10.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AA_kinase PF00696.28 KII91305.1 - 1.7e-38 132.6 0.0 5.1e-38 131.0 0.0 1.8 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KII91305.1 - 2.6e-10 39.9 0.2 5.1e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KII91305.1 - 1.1e-08 34.7 2.2 4.3e-06 26.4 0.3 2.9 3 0 0 3 3 3 2 ACT domain DUF5073 PF16817.5 KII91305.1 - 0.13 12.3 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5073) Sec1 PF00995.23 KII91306.1 - 4.2e-115 386.2 0.0 5.2e-115 385.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.6 KII91306.1 - 0.076 12.6 0.0 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain ChAPs PF09295.10 KII91307.1 - 9.8e-147 489.1 0.0 3.9e-145 483.8 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KII91307.1 - 4.3e-07 30.3 0.3 0.0016 18.9 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KII91307.1 - 6e-05 22.4 2.9 0.46 9.6 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII91307.1 - 0.0012 18.8 0.1 20 5.6 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII91307.1 - 0.0024 18.1 1.5 6.7 7.0 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KII91307.1 - 0.013 15.6 0.1 14 6.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 KII91307.1 - 0.094 11.6 0.1 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 KII91307.1 - 0.12 13.3 1.9 24 6.1 0.0 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII91307.1 - 0.13 12.9 3.6 96 4.0 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2046 PF09755.9 KII91308.1 - 1.4e-11 44.2 6.9 1.8e-11 43.8 4.4 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) FlaC_arch PF05377.11 KII91308.1 - 0.2 12.0 0.4 9.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HSP20 PF00011.21 KII91310.1 - 1.9e-10 40.8 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII91310.1 - 0.013 15.1 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA UB2H PF14814.6 KII91310.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain DER1 PF04511.15 KII91311.1 - 2e-32 112.7 3.0 2.4e-32 112.4 3.0 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KII91311.1 - 0.029 14.4 9.5 0.055 13.5 9.5 1.4 1 1 0 1 1 1 0 Rhomboid family Ion_trans_2 PF07885.16 KII91312.1 - 4.5e-28 97.0 30.8 2.3e-17 62.7 9.4 3.1 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 KII91312.1 - 0.0021 17.9 3.9 0.01 15.7 0.1 2.7 2 1 0 2 2 2 1 Ligand-gated ion channel Ion_trans PF00520.31 KII91312.1 - 0.0038 16.5 2.4 0.0038 16.5 2.4 3.4 2 1 1 3 3 3 2 Ion transport protein UL45 PF05473.12 KII91312.1 - 0.094 12.3 0.4 0.34 10.5 0.2 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like RNase_P_p30 PF01876.16 KII91312.1 - 0.13 11.8 0.0 0.4 10.1 0.0 1.7 2 0 0 2 2 2 0 RNase P subunit p30 FAM176 PF14851.6 KII91312.1 - 0.14 11.8 2.6 0.34 10.6 0.4 2.6 2 0 0 2 2 2 0 FAM176 family DUF1408 PF07193.11 KII91312.1 - 0.18 12.0 1.8 0.54 10.4 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) TauD PF02668.16 KII91313.1 - 7.1e-33 114.5 0.4 2.3e-32 112.9 0.0 1.8 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KII91313.1 - 0.0013 18.0 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 CsiD AAA_12 PF13087.6 KII91314.1 - 2.8e-44 151.1 0.0 7.2e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KII91314.1 - 2.3e-29 103.0 0.0 1.5e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KII91314.1 - 8.2e-13 48.5 0.0 2.3e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII91314.1 - 3.5e-11 43.6 0.0 1.7e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KII91314.1 - 7.4e-06 25.7 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.16 KII91314.1 - 0.00041 19.9 0.0 0.0091 15.5 0.0 2.3 1 1 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 KII91314.1 - 0.00044 20.3 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KII91314.1 - 0.00086 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII91314.1 - 0.0034 17.7 0.0 0.026 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KII91314.1 - 0.0036 17.1 0.0 8 6.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase OrsD PF12013.8 KII91314.1 - 0.023 15.2 0.5 0.42 11.1 0.2 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D UvrD_C_2 PF13538.6 KII91314.1 - 0.047 13.5 0.8 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 KII91314.1 - 0.055 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 1 0 Helicase AAA PF00004.29 KII91314.1 - 0.07 13.6 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII91314.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KII91314.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 KII91314.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KII91314.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KII91314.1 - 0.18 11.3 0.0 0.45 10.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PIGA PF08288.12 KII91315.1 - 1.4e-35 121.7 0.4 4.6e-35 120.1 0.4 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KII91315.1 - 2.4e-24 85.8 0.0 3.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KII91315.1 - 5.2e-24 85.2 2.4 1.2e-23 84.0 2.4 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KII91315.1 - 8.1e-22 78.1 0.1 1.5e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KII91315.1 - 4e-10 40.4 0.1 9.7e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KII91315.1 - 2.8e-05 24.4 0.0 6.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KII91315.1 - 0.016 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Oxysterol_BP PF01237.18 KII91317.1 - 7.5e-45 153.4 1.8 1.4e-25 90.0 1.3 3.5 2 1 0 2 2 2 2 Oxysterol-binding protein Pox_P4A PF03395.14 KII91319.1 - 0.12 9.9 0.0 0.15 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein CorA PF01544.18 KII91320.1 - 7.2e-09 35.4 1.4 1.4e-08 34.4 1.4 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PsaX PF08078.12 KII91320.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 PsaX family zf-RING_5 PF14634.6 KII91321.1 - 2e-05 24.4 13.2 2e-05 24.4 13.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII91321.1 - 0.00011 22.5 14.1 0.00011 22.5 14.1 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KII91321.1 - 0.00011 22.0 13.1 0.00011 22.0 13.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 KII91321.1 - 0.00017 21.8 1.8 0.00017 21.8 1.8 4.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C3HC4_2 PF13923.6 KII91321.1 - 0.00049 19.9 13.2 0.00049 19.9 13.2 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII91321.1 - 0.00056 19.7 11.4 0.00056 19.7 11.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII91321.1 - 0.0012 18.6 10.1 0.0012 18.6 10.1 2.8 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KII91321.1 - 0.0047 16.9 8.5 0.0047 16.9 8.5 3.3 2 2 0 2 2 2 1 RING-type zinc-finger zf-met PF12874.7 KII91321.1 - 0.0047 17.3 0.3 0.0047 17.3 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-RING_6 PF14835.6 KII91321.1 - 0.0052 16.6 8.8 0.0052 16.6 8.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF1213 PF06740.12 KII91321.1 - 0.0091 16.6 1.9 0.03 14.9 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1213) zf-C2H2_4 PF13894.6 KII91321.1 - 0.11 13.5 1.4 0.11 13.5 1.4 4.7 4 1 0 4 4 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KII91321.1 - 9.4 6.2 8.8 10 6.0 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif WD40 PF00400.32 KII91322.1 - 1.4e-18 66.9 15.2 0.0011 19.7 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91322.1 - 4.2e-06 27.0 4.8 0.0053 17.0 0.5 4.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII91322.1 - 0.003 16.6 0.0 0.97 8.3 0.1 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ADK_lid PF05191.14 KII91322.1 - 0.039 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid MFS_1 PF07690.16 KII91323.1 - 2.2e-51 174.8 21.9 3.1e-51 174.4 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII91323.1 - 1.1e-09 37.7 5.0 1.1e-09 37.7 5.0 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 KII91323.1 - 1.7e-07 29.9 1.8 5e-07 28.4 0.7 2.3 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Tail_VII PF17091.5 KII91323.1 - 0.055 13.3 0.7 0.055 13.3 0.7 3.2 4 0 0 4 4 4 0 Inovirus G7P protein SelK_SelG PF10961.8 KII91323.1 - 0.14 12.8 0.2 0.31 11.7 0.2 1.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG adh_short PF00106.25 KII91324.1 - 3.5e-13 49.5 0.1 7.1e-13 48.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91324.1 - 7.4e-10 38.8 0.1 9.7e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase zf-MYND PF01753.18 KII91325.1 - 7.8e-09 35.5 16.4 7.8e-09 35.5 16.4 2.1 2 0 0 2 2 2 1 MYND finger zf-ribbon_3 PF13248.6 KII91325.1 - 0.1 12.0 2.4 0.28 10.7 2.4 1.8 1 0 0 1 1 1 0 zinc-ribbon domain PolC_DP2 PF03833.13 KII91325.1 - 5.4 4.7 5.1 7.9 4.2 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 NAD_binding_10 PF13460.6 KII91326.1 - 1.8e-08 34.5 0.0 3.4e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII91326.1 - 0.017 14.6 0.0 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KII91326.1 - 0.075 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Bac_rhamnosid6H PF17389.2 KII91326.1 - 0.13 11.5 0.3 0.77 8.9 0.0 2.1 3 0 0 3 3 3 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Aminotran_1_2 PF00155.21 KII91327.1 - 1.9e-51 175.3 0.0 2.3e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 KII91328.1 - 7e-48 159.6 18.9 6.8e-10 39.4 1.1 7.7 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91328.1 - 2.5e-19 69.3 1.4 0.0023 18.2 0.0 6.3 4 1 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII91328.1 - 1.6e-05 24.1 0.5 0.43 9.5 0.0 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PHF5 PF03660.14 KII91329.1 - 1.9e-52 175.9 7.9 2.1e-52 175.7 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KII91329.1 - 0.038 11.9 4.8 0.042 11.7 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KII91329.1 - 0.42 10.7 15.0 1.6 8.8 1.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 KII91329.1 - 2 8.8 17.7 0.37 11.1 2.7 2.6 1 1 1 2 2 2 0 C1 domain UCH PF00443.29 KII91330.1 - 1.2e-41 142.9 0.0 1.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII91330.1 - 6.8e-12 45.6 0.0 8.8e-05 22.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.7 KII91330.1 - 0.12 12.5 0.5 0.43 10.7 0.5 1.9 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Bin3 PF06859.12 KII91331.1 - 2.1e-38 131.3 0.0 2.8e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 KII91331.1 - 5.5e-14 52.3 0.0 7.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII91331.1 - 1.6e-11 44.7 0.0 1.8e-06 28.6 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KII91331.1 - 2.6e-11 43.5 0.0 5.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KII91331.1 - 1.7e-08 35.0 0.0 0.00026 21.6 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 KII91331.1 - 3.5e-08 34.1 0.0 0.007 17.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.7 KII91331.1 - 0.00014 21.8 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KII91331.1 - 0.00018 21.0 0.0 0.00096 18.7 0.0 2.1 2 1 1 3 3 3 1 Putative methyltransferase PrmA PF06325.13 KII91331.1 - 0.00051 19.5 0.0 0.00097 18.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KII91331.1 - 0.00094 19.0 0.0 0.004 16.9 0.0 1.9 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KII91331.1 - 0.0011 18.4 0.1 0.077 12.3 0.1 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KII91331.1 - 0.0028 17.2 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KII91331.1 - 0.0031 16.9 0.0 0.095 12.0 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KII91331.1 - 0.074 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KII91331.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 KII91331.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DEAD PF00270.29 KII91332.1 - 3.1e-38 131.3 0.0 3.1e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KII91332.1 - 6.6e-21 74.7 0.0 6.4e-19 68.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII91332.1 - 0.059 13.4 0.0 0.69 9.9 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TMEM52 PF14979.6 KII91332.1 - 0.19 11.7 0.1 0.45 10.4 0.1 1.6 1 0 0 1 1 1 0 Transmembrane 52 CTP_synth_N PF06418.14 KII91333.1 - 7.2e-97 323.8 0.0 9.2e-97 323.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KII91333.1 - 4.2e-50 170.2 0.0 6.6e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KII91333.1 - 0.0022 17.8 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 CBFD_NFYB_HMF PF00808.23 KII91334.1 - 5.9e-15 55.3 0.8 1.1e-14 54.4 0.8 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII91334.1 - 2.4e-08 34.4 3.0 4.7e-08 33.5 3.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RICTOR_phospho PF14665.6 KII91334.1 - 0.048 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site MotA_activ PF09114.10 KII91334.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcription factor MotA, activation domain ABC_membrane PF00664.23 KII91335.1 - 5.4e-50 170.6 23.8 1e-25 90.9 4.5 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII91335.1 - 3.6e-40 137.6 0.1 2.7e-26 92.7 0.1 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII91335.1 - 9.8e-11 41.5 2.3 0.031 13.7 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KII91335.1 - 2.7e-06 27.0 0.5 0.0071 16.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KII91335.1 - 3.9e-06 26.1 0.2 0.00034 19.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 KII91335.1 - 5.2e-06 26.9 1.4 0.03 14.7 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 KII91335.1 - 1.4e-05 24.8 0.0 0.27 10.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KII91335.1 - 2.2e-05 25.0 1.3 0.00062 20.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KII91335.1 - 7.9e-05 22.6 0.7 0.33 10.7 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KII91335.1 - 0.00058 19.4 0.1 0.77 9.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KII91335.1 - 0.0014 18.9 0.4 0.61 10.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KII91335.1 - 0.0018 18.4 0.9 0.16 12.1 0.4 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII91335.1 - 0.0024 17.3 0.2 0.58 9.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KII91335.1 - 0.0059 16.7 0.6 0.59 10.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 KII91335.1 - 0.015 14.1 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 KII91335.1 - 0.017 15.0 0.1 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KII91335.1 - 0.031 14.8 0.0 2.7 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KII91335.1 - 0.032 14.0 0.0 6.9 6.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KII91335.1 - 0.033 13.9 0.2 0.63 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 KII91335.1 - 0.053 13.3 0.6 17 5.1 0.2 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 KII91335.1 - 0.06 13.3 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 KII91335.1 - 0.065 13.2 0.7 20 5.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 KII91335.1 - 0.071 12.6 1.2 9.9 5.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase_2 PF01637.18 KII91335.1 - 0.076 12.9 0.1 0.86 9.5 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KII91335.1 - 0.14 11.9 0.5 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KII91335.1 - 0.16 11.8 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 KII91335.1 - 0.16 12.0 0.4 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 KII91335.1 - 0.16 11.6 0.1 18 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KII91335.1 - 0.19 11.8 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KII91335.1 - 0.22 11.1 3.8 0.29 10.7 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KII91335.1 - 0.38 9.6 2.1 4.5 6.1 0.5 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KII91335.1 - 0.42 10.5 3.2 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 KII91335.1 - 0.43 10.5 1.4 6.4 6.7 0.2 2.6 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.9 KII91335.1 - 0.47 9.2 2.1 13 4.5 0.2 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class 2-Hacid_dh_C PF02826.19 KII91336.1 - 2.2e-40 137.9 0.0 3.5e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII91336.1 - 1.1e-21 76.9 0.0 1.4e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 KII91336.1 - 0.0031 18.1 0.0 0.0063 17.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 KII91338.1 - 2.8e-75 253.2 1.9 3.4e-75 252.9 1.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KII91338.1 - 3.5e-49 166.0 0.0 6.7e-49 165.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Lipocalin_4 PF13648.6 KII91339.1 - 1.3 10.1 6.7 3.1 8.8 1.9 2.5 2 1 0 2 2 2 0 Lipocalin-like domain Invasin_D3 PF09134.10 KII91339.1 - 3.2 8.1 6.7 14 6.0 4.3 2.7 2 1 1 3 3 3 0 Invasin, domain 3 adh_short PF00106.25 KII91340.1 - 7.6e-41 139.7 2.4 9.7e-40 136.1 2.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91340.1 - 2.9e-37 128.5 0.3 1.2e-36 126.4 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91340.1 - 2.8e-07 30.6 0.1 5.8e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 KR domain BAT PF15915.5 KII91340.1 - 0.087 12.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Eno-Rase_NADH_b PF12242.8 KII91340.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-RING_2 PF13639.6 KII91341.1 - 2.8e-07 30.8 9.0 5.3e-07 29.9 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KII91341.1 - 2.3e-05 24.5 5.3 4.8e-05 23.5 5.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KII91341.1 - 0.0036 17.6 7.5 0.0087 16.3 7.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII91341.1 - 0.0057 16.7 2.2 0.012 15.7 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KII91341.1 - 0.044 13.9 6.8 0.11 12.6 6.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KII91341.1 - 0.047 13.6 9.8 0.083 12.8 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KII91341.1 - 0.055 13.1 5.9 0.11 12.1 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Cnd1 PF12717.7 KII91341.1 - 0.07 13.2 0.2 0.97 9.5 0.1 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 zf-C3HC4_2 PF13923.6 KII91341.1 - 0.13 12.1 8.4 0.3 11.0 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KII91341.1 - 0.27 11.6 8.0 0.53 10.6 8.0 1.5 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 KII91341.1 - 1.6 8.7 5.0 0.67 9.9 2.6 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KII91341.1 - 2 8.3 6.9 6.4 6.7 6.9 1.8 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-RING_4 PF14570.6 KII91341.1 - 5.4 6.9 6.8 10 6.0 6.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Creatinase_N_2 PF16189.5 KII91342.1 - 1.8e-51 174.4 0.0 1.3e-50 171.6 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KII91342.1 - 2.9e-45 154.5 0.0 4.1e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KII91342.1 - 5.6e-24 84.0 0.0 2e-23 82.2 0.0 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KII91342.1 - 6.6e-21 75.3 0.0 5.7e-17 62.6 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain F-box-like PF12937.7 KII91343.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.3 2 0 0 2 2 2 0 F-box-like adh_short_C2 PF13561.6 KII91344.1 - 7.3e-56 189.3 2.9 1e-55 188.9 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII91344.1 - 5.4e-54 182.6 3.1 6.8e-54 182.3 3.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII91344.1 - 8.5e-08 32.3 1.4 1.2e-07 31.8 1.4 1.2 1 0 0 1 1 1 1 KR domain Imm68 PF15583.6 KII91344.1 - 0.19 11.9 0.0 7.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 68 adh_short_C2 PF13561.6 KII91345.1 - 2.5e-22 79.6 0.0 3.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII91345.1 - 9.9e-14 51.2 0.3 1.7e-13 50.5 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase bZIP_1 PF00170.21 KII91346.1 - 2.6e-08 33.8 6.1 4.9e-08 32.9 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII91346.1 - 8.7e-06 25.7 9.1 8.1e-05 22.6 3.9 2.5 1 1 1 2 2 2 2 Basic region leucine zipper TAP42 PF04177.12 KII91346.1 - 0.02 14.1 0.3 0.031 13.4 0.3 1.4 1 1 0 1 1 1 0 TAP42-like family SlyX PF04102.12 KII91346.1 - 0.1 13.2 0.1 3.5 8.3 0.0 2.5 2 0 0 2 2 2 0 SlyX bZIP_Maf PF03131.17 KII91346.1 - 2.1 8.9 8.9 0.15 12.6 3.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor PAP2 PF01569.21 KII91348.1 - 4.4e-18 65.4 4.9 1.5e-17 63.6 4.9 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KII91348.1 - 0.0073 16.0 11.1 0.0073 16.0 11.1 2.6 3 1 0 3 3 3 1 PAP2 superfamily DUF1614 PF07758.11 KII91348.1 - 0.01 15.8 1.0 0.81 9.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) PRiA4_ORF3 PF07929.11 KII91349.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein p450 PF00067.22 KII91350.1 - 6.4e-68 229.6 0.0 7.2e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SQS_PSY PF00494.19 KII91350.1 - 0.021 14.3 0.4 0.058 12.9 0.0 1.8 3 0 0 3 3 3 0 Squalene/phytoene synthase HLH PF00010.26 KII91351.1 - 3.8e-17 62.0 0.0 1.8e-16 59.8 0.0 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Tyrosinase PF00264.20 KII91355.1 - 1.1e-31 110.9 8.1 1.6e-31 110.3 8.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase IF4E PF01652.18 KII91357.1 - 2.8e-54 183.2 0.0 4e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2486 PF10667.9 KII91357.1 - 0.071 13.3 5.8 0.11 12.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF1102 PF06510.11 KII91357.1 - 0.082 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) ATP_bind_1 PF03029.17 KII91358.1 - 2.4e-75 253.4 0.0 2.9e-75 253.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KII91358.1 - 0.17 12.0 0.1 0.37 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KII91358.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRA1 PF07304.11 KII91359.1 - 2.3e-11 43.7 0.0 2.3e-11 43.7 0.0 2.9 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KII91359.1 - 1.5e-09 38.3 5.7 0.0024 18.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Prp18 PF02840.15 KII91359.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain Sec16_C PF12931.7 KII91359.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 DEAD PF00270.29 KII91361.1 - 8e-16 58.3 0.0 1.5e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII91361.1 - 5.3e-13 49.3 0.0 7.4e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII91361.1 - 1.4e-11 44.9 0.2 3.5e-11 43.7 0.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KII91361.1 - 9.3e-05 22.5 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RQC PF09382.10 KII91361.1 - 0.0004 20.1 0.2 0.0075 16.0 0.2 2.6 1 1 0 1 1 1 1 RQC domain Osmo_CC PF08946.10 KII91361.1 - 0.074 13.3 0.7 0.23 11.7 0.7 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF5082 PF16888.5 KII91361.1 - 0.09 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GPS2_interact PF15784.5 KII91361.1 - 2.7 8.5 4.9 3.4 8.2 0.3 2.4 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain GST_N_3 PF13417.6 KII91363.1 - 2.6e-10 40.6 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII91363.1 - 2.3e-09 37.2 0.2 4.7e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KII91363.1 - 4.1e-09 36.6 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII91363.1 - 1.6e-07 31.6 0.0 2.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 KII91363.1 - 1.3e-06 28.9 0.0 2.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KII91363.1 - 0.00028 21.0 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 KII91363.1 - 0.0025 18.0 0.0 0.0055 16.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII91363.1 - 0.012 15.8 0.1 0.024 14.8 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CPSF_A PF03178.15 KII91367.1 - 5e-79 265.9 0.0 9.2e-79 265.1 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KII91367.1 - 1.3e-14 53.7 0.0 2.4e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 KII91367.1 - 0.046 14.2 1.3 10 6.8 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain SET PF00856.28 KII91368.1 - 6.1e-10 39.7 1.0 1.7e-09 38.3 0.0 2.2 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KII91368.1 - 6.6e-08 32.9 15.2 6.6e-08 32.9 15.2 3.9 2 1 2 4 4 4 1 CXC domain Linocin_M18 PF04454.12 KII91369.1 - 0.074 12.3 0.1 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Encapsulating protein for peroxidase GreA_GreB_N PF03449.15 KII91369.1 - 0.12 12.5 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Unstab_antitox PF09720.10 KII91369.1 - 7.1 6.8 6.4 20 5.3 1.3 3.1 2 0 0 2 2 2 0 Putative addiction module component CBFD_NFYB_HMF PF00808.23 KII91370.1 - 6.5e-27 93.6 0.4 1.2e-26 92.8 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII91370.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KII91370.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KII91370.1 - 0.03 14.4 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 KII91370.1 - 0.038 13.8 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.13 KII91370.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 KII91370.1 - 0.19 12.2 0.1 0.66 10.5 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A LZ_Tnp_IS66 PF13007.7 KII91371.1 - 0.29 11.9 15.7 1.4 9.7 4.9 3.3 4 0 0 4 4 4 0 Transposase C of IS166 homeodomain DUF778 PF05608.12 KII91371.1 - 0.47 10.8 5.0 0.14 12.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF778) SOG2 PF10428.9 KII91371.1 - 1.8 7.7 17.6 2.4 7.3 17.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3886 PF13025.6 KII91371.1 - 2 8.7 12.3 5 7.4 12.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Hydin_ADK PF17213.3 KII91371.1 - 4.1 7.6 14.0 4.8 7.4 3.7 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Lyase_aromatic PF00221.19 KII91372.1 - 1.8e-135 452.3 4.2 1.7e-134 449.0 4.2 2.2 1 1 0 1 1 1 1 Aromatic amino acid lyase ANAPC4_WD40 PF12894.7 KII91373.1 - 0.0054 17.0 0.0 1.2 9.4 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII91373.1 - 0.0091 16.8 0.0 1.1 10.2 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat SET PF00856.28 KII91374.1 - 7.3e-13 49.3 0.1 2.4e-12 47.6 0.1 1.9 1 0 0 1 1 1 1 SET domain preSET_CXC PF18264.1 KII91374.1 - 1.7e-10 41.2 15.4 1.7e-10 41.2 15.4 3.5 3 1 0 3 3 3 1 CXC domain TCR PF03638.15 KII91374.1 - 3.3 8.1 48.0 0.11 12.8 15.1 3.4 3 0 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain MIF4G PF02854.19 KII91375.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 MIF4G domain APH PF01636.23 KII91376.1 - 9e-15 55.2 0.5 2.5e-14 53.8 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII91376.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LexA_DNA_bind PF01726.16 KII91378.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 LexA DNA binding domain RNA_lig_T4_1 PF09511.10 KII91379.1 - 2.7e-84 282.4 0.0 4.8e-84 281.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KII91379.1 - 3.9e-28 98.6 0.2 7e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KII91379.1 - 5.4e-23 81.7 0.0 2e-22 79.9 0.0 1.8 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain AAA_18 PF13238.6 KII91379.1 - 0.0082 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KII91379.1 - 0.041 13.3 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Exo70 PF03081.15 KII91380.1 - 1.1e-41 143.1 0.0 1.7e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Snapin_Pallidin PF14712.6 KII91380.1 - 1 9.8 7.2 0.18 12.3 1.6 2.6 3 0 0 3 3 3 0 Snapin/Pallidin Sec63 PF02889.16 KII91381.1 - 2.4e-161 534.9 0.0 7.4e-90 300.6 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KII91381.1 - 7e-49 166.0 0.4 1.5e-25 90.0 0.2 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KII91381.1 - 2.1e-34 118.0 0.0 7.5e-34 116.3 0.0 2.1 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KII91381.1 - 1.4e-24 87.0 0.7 2.3e-14 53.8 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII91381.1 - 4.2e-15 56.1 0.0 1.7e-08 34.7 0.0 4.4 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KII91381.1 - 5.4e-07 30.0 0.1 0.063 13.6 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KII91381.1 - 0.00014 21.6 0.2 0.37 10.5 0.1 2.8 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 KII91381.1 - 0.00087 18.8 0.0 0.026 14.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KII91381.1 - 0.0074 15.4 0.0 0.16 11.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein UDG PF03167.19 KII91382.1 - 3.5e-15 56.3 0.0 9.4e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily ORC6 PF05460.13 KII91383.1 - 1.3 8.2 6.9 1.5 8.1 6.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) F-box-like PF12937.7 KII91384.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KII91384.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 F-box DUF1582 PF07621.11 KII91385.1 - 0.013 15.4 16.2 1.3 9.0 0.3 5.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1582) DEAD PF00270.29 KII91386.1 - 3.5e-43 147.4 0.1 6.5e-43 146.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII91386.1 - 1.5e-20 73.6 0.0 1.6e-18 67.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII91386.1 - 2.2e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2795 PF11387.8 KII91386.1 - 0.047 13.9 0.3 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Phage_terminase PF10668.9 KII91386.1 - 1.2 9.2 3.3 5.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Phage terminase small subunit Kelch_4 PF13418.6 KII91387.1 - 1.9e-27 95.0 11.4 6.6e-07 29.2 0.1 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 KII91387.1 - 6.5e-27 93.2 9.4 1.1e-07 32.0 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KII91387.1 - 8.5e-19 67.1 5.0 3.4e-06 27.1 0.0 4.9 4 1 1 5 5 5 3 Kelch motif DUF4110 PF13422.6 KII91387.1 - 1.4e-16 60.4 0.1 1.4e-16 60.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 KII91387.1 - 5.5e-15 54.7 3.7 0.0008 19.0 0.0 5.2 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 KII91387.1 - 2.4e-12 46.6 15.6 0.005 16.8 0.2 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KII91387.1 - 3.9e-09 36.1 9.3 0.028 14.4 1.5 4.9 4 1 0 4 4 4 3 Kelch motif BUD22 PF09073.10 KII91387.1 - 0.089 12.1 16.9 0.57 9.5 3.2 2.3 2 0 0 2 2 2 0 BUD22 DUF3246 PF11596.8 KII91387.1 - 0.12 11.8 7.8 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Atg14 PF10186.9 KII91388.1 - 2.5e-49 168.1 0.0 4.1e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Zwint PF15556.6 KII91388.1 - 0.0013 18.3 1.4 0.002 17.6 1.4 1.3 1 0 0 1 1 1 1 ZW10 interactor HRDC PF00570.23 KII91388.1 - 0.021 14.8 0.5 0.04 13.9 0.5 1.5 1 0 0 1 1 1 0 HRDC domain HMMR_C PF15908.5 KII91388.1 - 0.026 14.8 0.4 0.043 14.1 0.4 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal EzrA PF06160.12 KII91388.1 - 0.085 11.0 0.4 0.11 10.6 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LMP PF04778.12 KII91388.1 - 0.1 12.5 0.4 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 LMP repeated region SlyX PF04102.12 KII91388.1 - 0.12 13.0 3.3 0.12 13.1 1.5 1.8 2 0 0 2 2 2 0 SlyX Fez1 PF06818.15 KII91388.1 - 0.17 12.3 2.7 0.31 11.4 2.7 1.4 1 0 0 1 1 1 0 Fez1 zf-B_box PF00643.24 KII91388.1 - 0.66 10.2 4.2 1.3 9.3 4.2 1.5 1 0 0 1 1 1 0 B-box zinc finger F-box-like PF12937.7 KII91389.1 - 1.3e-05 24.9 0.1 4e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.12 KII91390.1 - 6.4e-11 42.1 0.4 8.3e-11 41.7 0.4 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KII91390.1 - 7.8e-07 28.9 0.3 1.3e-06 28.2 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF5335 PF17269.2 KII91390.1 - 0.022 14.6 0.4 0.049 13.5 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5335) Tox-ART-HYE1 PF15634.6 KII91392.1 - 0.064 12.6 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase RVT_1 PF00078.27 KII91393.1 - 2.5e-08 33.7 0.0 2.6e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KII91394.1 - 1.7e-05 25.1 0.0 3.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 RNase H ADH_zinc_N PF00107.26 KII91395.1 - 5.5e-11 42.6 0.1 1.1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII91395.1 - 7e-06 25.7 0.0 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 KII91395.1 - 4.8e-05 23.2 0.2 8.9e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HI0933_like PF03486.14 KII91395.1 - 0.00023 20.0 0.3 0.00083 18.2 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KII91395.1 - 0.00067 19.0 0.1 0.00093 18.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KII91395.1 - 0.045 13.0 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KII91395.1 - 0.059 13.6 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KII91395.1 - 0.068 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KII91395.1 - 0.096 12.6 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KII91395.1 - 0.15 12.6 0.1 0.28 11.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L33 PF00471.20 KII91396.1 - 1.2e-08 35.3 0.0 1.5e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 KII91396.1 - 0.072 12.7 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal TnsD PF15978.5 KII91397.1 - 0.0014 17.7 0.5 0.0016 17.5 0.5 1.0 1 0 0 1 1 1 1 Tn7-like transposition protein D Robl_LC7 PF03259.17 KII91398.1 - 3.6e-06 26.7 0.0 2.4e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Roadblock/LC7 domain zf-MYND PF01753.18 KII91399.1 - 2.6e-08 33.8 11.3 2.6e-08 33.8 11.3 2.1 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 KII91399.1 - 0.25 11.7 4.0 0.5 10.7 4.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Metallophos_2 PF12850.7 KII91402.1 - 1.5e-15 57.8 0.0 2.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KII91402.1 - 0.011 16.3 0.0 0.037 14.5 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase MFS_1 PF07690.16 KII91403.1 - 8.5e-16 57.8 53.8 1.6e-14 53.6 50.8 3.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KII91403.1 - 1.1e-06 27.4 34.8 1.2e-05 24.0 34.8 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2976 PF11190.8 KII91403.1 - 3.3 7.6 12.3 2.5 8.0 1.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) BTB PF00651.31 KII91404.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KII91406.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.31 KII91407.1 - 7.5e-06 26.1 0.3 1.2e-05 25.5 0.3 1.3 1 0 0 1 1 1 1 BTB/POZ domain DIRP PF06584.13 KII91407.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 DIRP Glyoxal_oxid_N PF07250.11 KII91409.1 - 2.6e-30 105.4 1.4 9e-23 80.7 0.2 5.0 3 2 1 4 4 4 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KII91409.1 - 7.9e-24 83.8 0.3 2e-23 82.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KII91409.1 - 0.029 14.4 1.3 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Serglycin PF04360.12 KII91409.1 - 3.3 7.6 5.1 7.9 6.4 5.1 1.5 1 0 0 1 1 1 0 Serglycin zf-MYND PF01753.18 KII91410.1 - 6.7e-09 35.7 14.7 1.4e-08 34.6 14.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII91410.1 - 0.007 16.6 11.0 0.016 15.5 11.0 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Glyoxal_oxid_N PF07250.11 KII91411.1 - 3e-31 108.5 0.7 1.1e-15 57.6 0.0 5.0 3 2 2 5 5 5 4 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KII91411.1 - 7e-24 84.0 0.3 2.1e-23 82.4 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KII91411.1 - 0.058 13.4 1.8 1.7 8.7 0.1 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Questin_oxidase PF14027.6 KII91412.1 - 1.7e-100 336.9 0.0 2.1e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Chs7 PF12271.8 KII91413.1 - 1.2e-78 264.4 7.9 1.5e-78 264.1 7.9 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone F-box-like PF12937.7 KII91415.1 - 1.2e-06 28.3 0.8 2.3e-06 27.4 0.8 1.6 1 1 0 1 1 1 1 F-box-like HMG_box PF00505.19 KII91416.1 - 8.5e-11 42.1 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII91416.1 - 0.0081 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Aldo_ket_red PF00248.21 KII91417.1 - 5e-70 236.0 0.0 6.3e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KII91418.1 - 3e-06 27.0 4.7 3e-06 27.0 4.7 3.0 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KII91418.1 - 0.3 11.6 4.0 86 3.8 0.0 5.1 7 0 0 7 7 7 0 Leucine Rich repeats (2 copies) TolA_bind_tri PF16331.5 KII91418.1 - 7.9 6.6 8.3 0.43 10.7 2.2 2.0 3 0 0 3 3 3 0 TolA binding protein trimerisation GPP34 PF05719.11 KII91424.1 - 1.8e-65 220.8 0.1 2.3e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) 3HCDH_N PF02737.18 KII91424.1 - 0.18 11.7 0.2 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G-alpha PF00503.20 KII91425.1 - 3.2e-114 381.8 0.0 3.8e-114 381.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91425.1 - 3.8e-12 46.0 0.6 4.2e-08 32.8 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 KII91425.1 - 0.0019 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KII91425.1 - 0.0051 17.0 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KII91425.1 - 0.011 15.5 0.1 0.028 14.2 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 KII91425.1 - 0.016 14.6 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII91425.1 - 0.037 13.6 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KII91425.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KII91425.1 - 0.062 13.5 0.1 4.1 7.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KII91425.1 - 0.085 13.1 0.1 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KII91425.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF5069 PF16798.5 KII91425.1 - 0.094 12.9 0.5 0.29 11.3 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) AAA_24 PF13479.6 KII91425.1 - 0.11 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Acetyltransf_10 PF13673.7 KII91428.1 - 1.4e-11 44.4 0.0 2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII91428.1 - 1.1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII91428.1 - 7.1e-08 32.7 0.0 8.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII91428.1 - 7.4e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KII91428.1 - 0.0027 17.8 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KII91428.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ANAPC4_WD40 PF12894.7 KII91429.1 - 8.7e-19 67.6 4.0 3.8e-07 30.3 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII91429.1 - 1.3e-16 60.6 14.5 1.1e-05 26.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 KII91429.1 - 0.00047 20.1 0.0 0.053 13.4 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KII91429.1 - 0.0015 17.5 0.1 0.38 9.7 0.0 3.3 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase_Tyr PF07714.17 KII91431.1 - 9.8e-39 133.2 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII91431.1 - 1.1e-32 113.5 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII91431.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII91431.1 - 0.0014 18.6 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII91431.1 - 0.0064 15.3 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII91431.1 - 0.0073 15.7 0.3 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KII91431.1 - 0.082 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KII91431.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family 4HBT PF03061.22 KII91432.1 - 2.7e-12 46.9 0.0 4.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KII91432.1 - 2.5e-05 24.8 0.0 3.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KII91432.1 - 0.00056 19.3 0.3 0.00077 18.8 0.3 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase Proteasome PF00227.26 KII91433.1 - 3.3e-37 127.8 0.0 4e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sad1_UNC PF07738.13 KII91435.1 - 2e-20 73.1 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal VID27_PH PF17747.1 KII91436.1 - 0.072 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 VID27 PH-like domain MCM_lid PF17855.1 KII91438.1 - 0.0079 16.6 0.1 0.012 16.0 0.1 1.4 1 1 0 1 1 1 1 MCM AAA-lid domain Swi6_N PF18530.1 KII91438.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Swi6 N-terminal domain TetR_C_30 PF17939.1 KII91438.1 - 0.048 13.9 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF587 PF04532.12 KII91439.1 - 0.053 12.8 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF587) DUF4218 PF13960.6 KII91440.1 - 0.00055 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) GAIN PF16489.5 KII91440.1 - 0.11 11.9 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF3035 PF11233.8 KII91442.1 - 0.019 15.2 0.9 0.019 15.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) MSA-2c PF12238.8 KII91442.1 - 0.75 9.8 3.3 0.83 9.6 3.3 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c G-alpha PF00503.20 KII91443.1 - 5.4e-102 341.6 0.5 6.3e-102 341.4 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII91443.1 - 1.7e-14 53.7 0.3 4.8e-10 39.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII91443.1 - 2.4e-05 23.8 0.2 0.04 13.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KII91443.1 - 0.0023 18.2 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KII91443.1 - 0.018 14.8 0.1 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KII91443.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KII91443.1 - 0.13 11.8 0.1 5.7 6.4 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SNF2_N PF00176.23 KII91444.1 - 1.3e-66 224.8 0.0 1.9e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII91444.1 - 8.2e-20 71.2 0.0 1.6e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII91444.1 - 3.8e-06 27.0 0.0 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KII91444.1 - 7.9e-05 22.5 0.0 0.00019 21.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3584 PF12128.8 KII91445.1 - 0.0002 19.1 7.3 0.00026 18.7 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.19 KII91445.1 - 0.0099 13.7 5.2 0.015 13.1 5.2 1.2 1 0 0 1 1 1 1 Myosin tail Occludin_ELL PF07303.13 KII91445.1 - 0.092 13.5 1.0 0.28 11.9 0.5 2.0 2 0 0 2 2 2 0 Occludin homology domain Uso1_p115_C PF04871.13 KII91445.1 - 0.15 12.4 6.5 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HalX PF08663.10 KII91445.1 - 1.4 9.3 5.7 5.7 7.3 0.0 3.8 4 0 0 4 4 4 0 HalX domain HMMR_N PF15905.5 KII91445.1 - 1.9 7.9 8.4 1.7 8.1 0.1 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KII91445.1 - 2 8.6 5.0 48 4.1 3.0 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 KII91445.1 - 2.5 6.9 9.2 1.4 7.7 4.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1515 PF07439.11 KII91445.1 - 3.8 7.6 4.6 14 5.8 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) GAS PF13851.6 KII91445.1 - 4.5 6.6 8.5 1.6 8.1 4.3 2.0 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KII91445.1 - 6.8 6.3 10.9 6.4 6.4 9.0 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TolA_bind_tri PF16331.5 KII91446.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation Peptidase_M75 PF09375.10 KII91447.1 - 0.067 12.7 0.1 2.1 7.8 0.0 2.4 3 0 0 3 3 3 0 Imelysin JmjC PF02373.22 KII91448.1 - 0.003 18.0 0.0 0.0078 16.6 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase CMD PF02627.20 KII91449.1 - 1.5e-10 40.9 0.1 2.6e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Glyco_hydr_30_2 PF14587.6 KII91451.1 - 2.4e-16 60.3 2.6 6.3e-16 58.9 2.6 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 ICMT PF04140.14 KII91452.1 - 1.1e-14 54.6 0.2 4.2e-14 52.7 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII91452.1 - 7.6e-12 45.6 2.2 5.9e-11 42.7 0.7 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII91452.1 - 0.01 14.7 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KII91452.1 - 0.018 14.6 1.6 0.021 14.4 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) NiFeSe_Hases PF00374.19 KII91452.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DSPc PF00782.20 KII91453.1 - 6e-24 84.4 0.0 8.7e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII91453.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KII91453.1 - 0.045 14.1 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 Rit1 DUSP-like domain Ribosomal_S8 PF00410.19 KII91455.1 - 1.9e-24 86.0 0.1 2.6e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.18 KII91456.1 - 1.8e-60 202.2 0.0 2.2e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cu_amine_oxid PF01179.20 KII91457.1 - 1.5e-155 518.2 0.0 1.8e-155 517.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KII91457.1 - 4.8e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KII91457.1 - 6.9e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Hist_deacetyl PF00850.19 KII91458.1 - 2e-72 244.3 0.5 2.8e-72 243.8 0.5 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SSF PF00474.17 KII91459.1 - 1.3e-14 53.9 30.3 1.3e-14 53.9 30.3 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family CAS_CSE1 PF03378.15 KII91460.1 - 2.3e-116 388.9 0.0 3.4e-116 388.4 0.0 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KII91460.1 - 2e-99 332.9 0.0 3.1e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KII91460.1 - 5.3e-11 42.3 0.0 2.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KII91460.1 - 0.0046 17.0 0.4 0.093 12.8 0.0 3.3 3 1 0 3 3 3 1 Exportin 1-like protein Ctr PF04145.15 KII91460.1 - 0.037 14.6 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Ctr copper transporter family SapB_2 PF03489.17 KII91460.1 - 0.89 9.7 2.3 12 6.2 0.5 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 Sec10 PF07393.11 KII91464.1 - 3.1e-131 439.1 0.0 3.9e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 KII91464.1 - 2.2e-06 27.4 0.3 4.5e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII91464.1 - 3.2e-05 23.7 0.6 0.00019 21.3 0.7 2.1 2 0 0 2 2 2 1 F-box-like Rubella_E1 PF05748.11 KII91465.1 - 0.22 10.4 2.7 0.27 10.1 2.7 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 Mre11_DNA_bind PF04152.14 KII91468.1 - 8.3e-53 179.2 0.0 8.3e-53 179.2 0.0 2.5 3 1 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KII91468.1 - 1.9e-15 57.9 0.9 3e-15 57.3 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII91468.1 - 3.1e-06 27.5 0.1 8.9e-05 22.7 0.1 2.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.16 KII91469.1 - 3e-16 59.6 21.4 3.7e-16 59.3 21.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KII91469.1 - 2.3e-06 27.8 37.1 0.0014 18.8 16.9 2.7 2 1 0 2 2 2 2 EamA-like transporter family UDPG_MGDP_dh_N PF03721.14 KII91470.1 - 6.9e-59 198.6 0.0 1.7e-58 197.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KII91470.1 - 2e-34 118.2 0.3 7.6e-34 116.3 0.3 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KII91470.1 - 1.6e-30 105.2 0.0 3.8e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KII91470.1 - 0.028 14.6 0.1 0.56 10.4 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII91470.1 - 0.075 13.6 1.5 0.63 10.7 0.1 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 KII91470.1 - 0.14 12.3 0.1 6.2 6.9 0.0 2.8 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF5572 PF17733.1 KII91471.1 - 5.7e-20 70.9 0.5 1.1e-19 70.0 0.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) p450 PF00067.22 KII91472.1 - 4.3e-80 269.7 0.0 5.2e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GDP_Man_Dehyd PF16363.5 KII91473.1 - 2.4e-157 523.6 0.0 2.7e-157 523.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KII91473.1 - 1.7e-70 237.2 0.0 2.3e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KII91473.1 - 0.00067 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KII91473.1 - 0.013 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TAA-Trp-ring PF15401.6 KII91473.1 - 0.018 15.5 0.1 0.041 14.4 0.1 1.6 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin NmrA PF05368.13 KII91473.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 KII91474.1 - 3.5e-52 177.3 0.0 4.6e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII91474.1 - 7.8e-15 55.1 0.3 3.9e-14 52.8 0.3 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KII91474.1 - 5.5e-05 22.4 0.4 0.0064 15.7 0.3 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KII91474.1 - 0.00025 20.2 0.0 0.00055 19.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KII91474.1 - 0.0024 16.9 0.0 0.0051 15.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DEAD PF00270.29 KII91475.1 - 3.2e-17 62.8 0.0 5.1e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bromodomain PF00439.25 KII91475.1 - 1.4e-12 47.5 0.1 4.3e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KII91475.1 - 2.1e-05 24.8 0.0 0.00015 22.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII91475.1 - 0.00012 22.2 0.0 0.00035 20.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_M24 PF00557.24 KII91477.1 - 1.1e-57 195.2 0.0 1.4e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KII91477.1 - 2.7e-21 75.6 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GFO_IDH_MocA PF01408.22 KII91478.1 - 4.5e-13 50.1 0.0 8.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII91478.1 - 0.0035 17.4 0.0 0.0075 16.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain BPL_N PF09825.9 KII91479.1 - 3.9e-47 161.1 0.0 2.8e-45 155.0 0.0 2.5 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KII91479.1 - 1.4e-19 70.3 0.0 2.4e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ABC_transp_aux PF09822.9 KII91479.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system ThuA PF06283.11 KII91479.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation SNF2_N PF00176.23 KII91481.1 - 1.2e-70 238.0 0.1 2.1e-70 237.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII91481.1 - 2.1e-22 79.6 0.0 4.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KII91481.1 - 0.006 15.8 0.1 0.061 12.5 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KII91481.1 - 0.036 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 KII91481.1 - 0.051 13.2 0.5 3.3 7.3 0.0 3.0 3 0 0 3 3 3 0 DEAD_2 EST1_DNA_bind PF10373.9 KII91482.1 - 5.6e-27 95.0 0.0 1.2e-26 93.8 0.0 1.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KII91482.1 - 2.2e-21 76.9 0.0 6.8e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 PAPS_reduct PF01507.19 KII91483.1 - 1.4e-26 93.6 0.0 5e-26 91.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SPOB_ab PF14682.6 KII91483.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal GCS PF03074.16 KII91484.1 - 4.1e-162 539.7 0.0 4.9e-162 539.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Peptidase_M20 PF01546.28 KII91485.1 - 1.6e-33 116.2 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KII91485.1 - 9.3e-13 48.1 0.0 1.7e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KII91485.1 - 0.061 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Aminotran_1_2 PF00155.21 KII91486.1 - 1.4e-52 179.1 0.0 3.5e-50 171.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 KII91486.1 - 0.0086 14.9 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 KII91486.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V F-box PF00646.33 KII91488.1 - 2.8e-05 23.8 0.1 2.8e-05 23.8 0.1 3.1 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 KII91488.1 - 0.031 14.2 3.0 0.049 13.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like DUF3562 PF12085.8 KII91488.1 - 1.5 8.5 3.9 3 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) Zn_ribbon_2 PF12674.7 KII91488.1 - 9.9 6.9 7.8 2.1 9.1 0.1 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain ArfGap PF01412.18 KII91489.1 - 7.1e-40 135.7 0.4 1e-39 135.2 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NUDIX PF00293.28 KII91490.1 - 1.3e-12 47.9 0.0 2.1e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain SUZ PF12752.7 KII91491.1 - 1.7e-13 51.1 0.3 1.7e-13 51.1 0.3 2.9 3 0 0 3 3 3 1 SUZ domain Dus PF01207.17 KII91492.1 - 1.2e-52 179.0 0.0 1.8e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KII91492.1 - 2.7e-06 27.1 3.4 0.03 14.1 0.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 KII91492.1 - 3.7e-05 23.5 4.3 0.00054 19.8 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KII91492.1 - 0.022 15.5 0.8 8.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Torus domain zf_CCCH_4 PF18345.1 KII91492.1 - 0.1 12.7 6.2 2 8.6 0.7 2.4 2 0 0 2 2 2 0 Zinc finger domain Fungal_trans PF04082.18 KII91493.1 - 3.6e-30 104.9 0.0 7.9e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91493.1 - 6.1e-05 23.1 14.4 0.0001 22.4 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF775 PF05603.12 KII91494.1 - 4e-53 179.9 0.0 4.7e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FA_desaturase PF00487.24 KII91495.1 - 1.3e-27 97.2 25.5 2.2e-27 96.5 25.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KII91495.1 - 2.2e-06 27.9 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pro-kuma_activ PF09286.11 KII91496.1 - 8e-47 159.1 0.1 6.2e-46 156.2 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII91496.1 - 0.0011 18.4 1.0 0.0018 17.6 1.0 1.3 1 0 0 1 1 1 1 Subtilase family F-box PF00646.33 KII91497.1 - 0.0028 17.5 0.9 0.0051 16.7 0.9 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII91497.1 - 0.0084 16.0 0.3 0.012 15.5 0.3 1.2 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KII91497.1 - 0.0094 15.8 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 1 F-box FA_desaturase PF00487.24 KII91499.1 - 1.2e-27 97.4 24.4 1.9e-27 96.7 24.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KII91499.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) NAD_binding_5 PF07994.12 KII91501.1 - 0.21 10.9 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Epimerase PF01370.21 KII91502.1 - 5e-21 75.3 0.3 2.4e-20 73.1 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII91502.1 - 4.6e-16 58.7 0.0 8.5e-16 57.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KII91502.1 - 5.6e-11 42.7 0.1 9.5e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII91502.1 - 1.1e-09 38.2 0.5 4.1e-09 36.3 0.1 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KII91502.1 - 1.1e-08 34.6 0.0 1e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KII91502.1 - 6.6e-05 22.6 0.3 0.00011 21.9 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 KII91502.1 - 0.0017 17.9 0.7 0.021 14.3 0.5 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KII91502.1 - 0.0041 16.3 0.1 0.0063 15.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD40 PF00400.32 KII91503.1 - 1e-26 92.6 5.9 0.00017 22.3 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91503.1 - 0.00058 20.1 0.0 0.0085 16.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII91503.1 - 0.09 12.1 0.0 9 5.5 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain Kelch_6 PF13964.6 KII91503.1 - 0.18 12.1 0.3 11 6.5 0.0 3.3 4 0 0 4 4 4 0 Kelch motif CDC27 PF09507.10 KII91503.1 - 0.88 8.9 7.1 1.5 8.1 7.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Aminotran_1_2 PF00155.21 KII91504.1 - 1.9e-38 132.6 0.0 2.5e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_2 PF07719.17 KII91505.1 - 9.5e-06 25.4 3.7 0.0069 16.4 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII91505.1 - 0.00045 19.9 1.3 0.53 10.0 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KII91505.1 - 0.00049 20.3 1.6 1.6 9.3 0.2 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII91505.1 - 0.00061 20.2 5.2 1.2 9.6 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII91505.1 - 0.29 11.0 3.3 5.8 6.9 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII91505.1 - 0.45 11.2 5.5 0.37 11.5 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII91505.1 - 5.3 8.1 8.2 50 5.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KII91507.1 - 1.2e-08 34.4 13.2 0.0078 16.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII91507.1 - 1.1e-05 25.0 7.3 1.6 8.7 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII91507.1 - 0.0004 20.0 3.0 0.0013 18.4 0.1 3.0 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 KII91507.1 - 0.0016 18.7 6.9 0.064 13.6 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII91507.1 - 0.057 13.8 7.1 0.47 10.9 0.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII91507.1 - 0.35 11.8 12.1 18 6.5 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII91507.1 - 0.46 11.2 12.0 1.5 9.5 0.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DAO PF01266.24 KII91508.1 - 7.2e-29 101.5 1.3 9.1e-29 101.1 1.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII91508.1 - 0.014 15.6 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_6 PF12697.7 KII91511.1 - 5.7e-14 53.2 7.7 1.1e-13 52.3 7.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII91511.1 - 0.00071 18.9 0.1 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 p450 PF00067.22 KII91512.1 - 1.1e-65 222.2 0.0 2.3e-65 221.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII91513.1 - 3.7e-66 223.8 0.0 6.7e-66 222.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Copper-fist PF00649.18 KII91514.1 - 2e-20 71.9 1.4 2e-20 71.9 1.4 2.9 2 1 1 3 3 3 1 Copper fist DNA binding domain F-box-like PF12937.7 KII91518.1 - 0.015 15.2 0.3 0.043 13.7 0.3 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KII91519.1 - 0.052 13.5 0.3 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 F-box-like Fer2 PF00111.27 KII91520.1 - 1.2e-11 44.4 0.1 1.7e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pro-kuma_activ PF09286.11 KII91521.1 - 8.9e-38 129.8 0.0 2.6e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII91521.1 - 1.7e-06 27.6 1.4 2.9e-06 26.8 1.4 1.3 1 0 0 1 1 1 1 Subtilase family MMR_HSR1 PF01926.23 KII91522.1 - 1.7e-06 28.1 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KII91522.1 - 0.00011 21.6 0.0 0.083 12.2 0.0 2.2 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 KII91522.1 - 0.00019 21.4 0.2 0.0066 16.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KII91522.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 KII91522.1 - 0.0025 18.0 0.1 0.0068 16.6 0.0 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KII91522.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KII91522.1 - 0.043 13.7 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KII91522.1 - 0.047 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 KII91522.1 - 0.058 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Ras PF00071.22 KII91522.1 - 0.059 13.0 0.2 0.2 11.3 0.0 2.0 3 0 0 3 3 3 0 Ras family AAA_29 PF13555.6 KII91522.1 - 0.065 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KII91522.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 KII91522.1 - 0.075 13.6 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KII91522.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KII91522.1 - 0.09 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KII91522.1 - 0.18 12.2 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DnaJ PF00226.31 KII91523.1 - 2.2e-16 59.7 0.2 6.8e-16 58.1 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain AAA_23 PF13476.6 KII91523.1 - 0.55 10.7 15.9 0.072 13.6 12.0 1.6 2 0 0 2 2 2 0 AAA domain TFB6 PF17110.5 KII91523.1 - 2.4 7.9 8.0 5.2 6.8 8.0 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Paf1 PF03985.13 KII91523.1 - 4.7 6.1 27.4 0.11 11.5 20.1 1.8 2 0 0 2 2 2 0 Paf1 DNA_pol_A_exo1 PF01612.20 KII91524.1 - 3e-13 49.8 0.0 9.8e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Trimer_CC PF08954.11 KII91524.1 - 0.28 10.8 3.8 28 4.4 0.0 3.5 2 0 0 2 2 2 0 Trimerisation motif PQ-loop PF04193.14 KII91525.1 - 2.8e-17 62.2 4.8 3.3e-09 36.4 0.2 3.7 4 0 0 4 4 4 2 PQ loop repeat DUF3328 PF11807.8 KII91525.1 - 0.77 9.5 5.8 1.1 9.0 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Adap_comp_sub PF00928.21 KII91526.1 - 1.6e-91 306.4 0.0 3e-91 305.4 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KII91526.1 - 1.1e-06 28.7 0.3 1.9e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KII91526.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mon1 PF03164.14 KII91526.1 - 0.054 12.6 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 4HBT PF03061.22 KII91529.1 - 3.1e-07 30.6 0.2 6.5e-07 29.6 0.1 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 KII91529.1 - 0.00039 20.8 0.0 0.00059 20.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily PHP PF02811.19 KII91530.1 - 3.6e-12 46.9 0.2 8.8e-12 45.6 0.2 1.6 1 1 0 1 1 1 1 PHP domain Rnk_N PF14760.6 KII91530.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 Rnk N-terminus DUF1688 PF07958.11 KII91532.1 - 1.5e-175 583.9 0.0 1.7e-175 583.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.6 KII91533.1 - 3.4e-10 39.1 8.5 3.4e-10 39.1 8.5 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KII91533.1 - 0.0015 17.5 5.3 0.004 16.1 5.3 1.7 1 1 0 1 1 1 1 MFS_1 like family BT1 PF03092.16 KII91533.1 - 0.0068 14.7 1.2 0.0082 14.4 0.1 1.6 2 0 0 2 2 2 1 BT1 family DUF3619 PF12279.8 KII91533.1 - 0.15 12.4 0.3 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) ETF_QO PF05187.13 KII91534.1 - 8.7e-34 115.8 0.5 9.5e-32 109.2 0.5 2.4 1 1 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KII91534.1 - 5.2e-07 29.8 0.0 1.4e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII91534.1 - 8e-07 29.0 0.1 3.2e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII91534.1 - 1.4e-05 24.5 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII91534.1 - 2.1e-05 23.8 1.2 0.00016 20.9 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KII91534.1 - 2.8e-05 23.5 0.0 0.0032 16.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KII91534.1 - 0.00019 20.2 0.6 0.00028 19.7 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KII91534.1 - 0.00033 20.0 0.1 0.0005 19.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KII91534.1 - 0.00034 20.0 0.9 0.00065 19.0 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII91534.1 - 0.0012 18.8 0.2 0.0022 18.0 0.2 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KII91534.1 - 0.0054 16.1 0.2 0.0099 15.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KII91534.1 - 0.0055 15.8 0.2 0.0083 15.2 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 KII91534.1 - 0.012 16.2 0.2 0.039 14.6 0.3 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain Trp_halogenase PF04820.14 KII91534.1 - 0.015 14.1 0.2 0.026 13.4 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KII91534.1 - 0.093 13.3 0.3 4.6 7.9 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KII91534.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KII91534.1 - 0.14 11.3 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_10 PF13237.6 KII91534.1 - 0.17 12.1 0.5 0.43 10.7 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Methyltransf_10 PF05971.12 KII91536.1 - 5.3e-69 232.8 0.0 6.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KII91536.1 - 0.0019 17.8 0.0 0.0096 15.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KII91536.1 - 0.0059 16.0 0.1 0.0089 15.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TrmK PF04816.12 KII91536.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 KII91536.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain VIGSSK PF14773.6 KII91536.1 - 0.23 11.6 0.5 8.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal p450 PF00067.22 KII91537.1 - 1.4e-65 221.9 0.0 3.3e-65 220.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Cyt_b-c1_8 PF10890.8 KII91537.1 - 0.17 12.3 0.0 0.82 10.1 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 p450 PF00067.22 KII91538.1 - 9.4e-69 232.3 0.0 1.9e-68 231.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KII91540.1 - 1.8e-23 83.0 0.0 3.5e-19 69.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91540.1 - 1.1e-11 44.8 0.0 9.4e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91540.1 - 0.00025 21.0 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII91540.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 KII91540.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 KII91540.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UQ_con PF00179.26 KII91541.1 - 2.2e-49 166.7 0.0 2.6e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KII91541.1 - 0.0001 22.0 0.1 0.0013 18.5 0.0 2.0 1 1 1 2 2 2 2 Prokaryotic E2 family B HAT PF02184.16 KII91542.1 - 1.7e-24 85.5 49.2 9.2e-08 31.9 2.6 14.2 15 1 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KII91542.1 - 5.5e-24 82.8 29.6 0.0013 19.4 0.0 11.9 3 2 10 13 13 13 9 Tetratricopeptide repeat TPR_19 PF14559.6 KII91542.1 - 6.9e-17 61.7 0.1 0.026 15.0 0.0 6.8 5 1 3 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 KII91542.1 - 1e-15 58.6 8.2 0.00016 21.8 0.2 6.1 3 2 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KII91542.1 - 6.6e-12 44.6 4.4 1.5 9.1 0.0 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII91542.1 - 2.6e-08 33.7 0.3 0.0005 20.3 0.0 5.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII91542.1 - 9.5e-08 32.6 10.3 0.22 12.2 0.0 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat SNAP PF14938.6 KII91542.1 - 1.3e-06 28.1 1.3 0.00047 19.7 0.5 3.6 4 0 0 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 KII91542.1 - 3.6e-06 26.4 17.8 0.18 11.0 5.6 5.9 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII91542.1 - 2.6e-05 24.1 0.6 79 3.9 0.0 7.2 6 1 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII91542.1 - 4.1e-05 23.7 8.2 1 9.5 0.1 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII91542.1 - 6.1e-05 22.7 0.7 50 3.9 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII91542.1 - 0.00058 19.7 9.5 14 6.0 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII91542.1 - 0.0019 18.7 9.1 67 4.4 0.1 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KII91542.1 - 0.0063 16.6 16.2 0.042 13.9 0.6 6.2 4 3 3 7 7 7 1 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 KII91542.1 - 0.13 12.6 15.3 5 7.5 0.1 6.9 6 1 2 8 8 7 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 KII91542.1 - 0.47 10.7 3.5 2.3 8.5 0.5 3.4 4 0 0 4 4 3 0 c-SKI Smad4 binding domain Promethin PF16015.5 KII91543.1 - 3.9e-12 46.0 17.5 5e-12 45.7 17.5 1.2 1 0 0 1 1 1 1 Promethin DnaJ PF00226.31 KII91544.1 - 3.7e-17 62.2 5.0 7.9e-17 61.1 5.0 1.6 1 0 0 1 1 1 1 DnaJ domain TGT PF01702.18 KII91545.1 - 1.3e-38 133.1 0.0 2.3e-23 82.9 0.0 2.0 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Amidase PF01425.21 KII91546.1 - 7.1e-75 252.7 0.0 1.8e-73 248.1 0.0 2.0 1 1 0 1 1 1 1 Amidase His_Phos_2 PF00328.22 KII91547.1 - 1.7e-47 162.6 0.0 2.4e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3684 PF12449.8 KII91548.1 - 0 1185.0 0.0 0 1184.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Spo7 PF03907.13 KII91549.1 - 2.9e-40 138.1 0.6 8.1e-40 136.6 0.6 1.6 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 KII91549.1 - 0.00069 20.0 0.1 0.0018 18.6 0.1 1.7 1 1 0 1 1 1 1 Transmembrane protein 188 p450 PF00067.22 KII91550.1 - 8.2e-66 222.6 0.0 1.9e-65 221.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.18 KII91554.1 - 2.4e-11 43.4 14.4 2.4e-11 43.4 14.4 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain CFEM PF05730.11 KII91555.1 - 6.2e-13 48.6 12.1 6.2e-13 48.6 12.1 1.6 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.11 KII91555.1 - 2 6.4 11.0 2.1 6.3 11.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L34e PF01199.18 KII91556.1 - 5.3e-44 148.5 2.4 7.4e-44 148.0 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KII91556.1 - 0.25 11.3 5.2 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain EndIII_4Fe-2S PF10576.9 KII91556.1 - 0.45 10.9 2.8 0.61 10.5 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribosomal_L31e PF01198.19 KII91557.1 - 2.7e-42 142.9 2.3 3.6e-42 142.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 KII91557.1 - 0.039 14.0 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein EHN PF06441.12 KII91559.1 - 1.2e-33 115.7 0.8 4.5e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII91559.1 - 2.9e-08 33.7 0.0 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII91559.1 - 0.0027 18.3 6.7 0.0068 17.0 6.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAP59_mtransfer PF11735.8 KII91560.1 - 7.7e-68 228.8 0.0 9.9e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RPN7 PF10602.9 KII91561.1 - 7.8e-39 133.2 0.0 1.7e-38 132.0 0.0 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KII91561.1 - 1.8e-14 54.1 0.0 5.8e-14 52.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 KII91561.1 - 0.00013 21.8 1.4 1 9.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII91561.1 - 0.00063 19.6 0.0 0.31 11.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII91561.1 - 0.0031 17.3 3.6 0.33 10.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII91561.1 - 0.078 13.2 0.1 27 5.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 KII91561.1 - 2.8 8.6 8.8 0.37 11.4 3.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop53 PF07767.11 KII91562.1 - 1.2e-93 314.7 13.0 1.5e-93 314.3 13.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.12 KII91562.1 - 0.022 14.7 0.8 0.022 14.7 0.8 1.8 2 0 0 2 2 2 0 BOP1NT (NUC169) domain BTB PF00651.31 KII91563.1 - 3.6e-10 40.1 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII91564.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain rhaM PF05336.13 KII91566.1 - 4.5e-32 110.3 0.0 5e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Aminotran_1_2 PF00155.21 KII91569.1 - 6.9e-36 124.2 0.0 8.7e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII91569.1 - 0.013 14.0 0.0 0.046 12.2 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.7 KII91570.1 - 0.026 14.4 2.3 0.029 14.3 0.4 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KII91570.1 - 1 9.3 5.2 0.18 11.7 1.1 1.9 2 0 0 2 2 2 0 F-box domain RNA_Me_trans PF04252.13 KII91571.1 - 5e-78 261.3 0.0 5.6e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.25 KII91572.1 - 3.1e-61 207.0 0.0 6.4e-61 206.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91572.1 - 4.9e-44 150.6 0.0 8.7e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 KII91572.1 - 2.9e-38 131.7 0.1 6.6e-38 130.5 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 KII91572.1 - 0.0003 20.2 0.0 0.0029 17.0 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KII91572.1 - 0.0068 16.3 0.1 0.072 13.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII91572.1 - 0.029 13.1 0.0 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Alginate_lyase PF05426.12 KII91574.1 - 5.1e-57 193.5 3.0 9.7e-57 192.6 3.0 1.4 1 0 0 1 1 1 1 Alginate lyase Pneumo_att_G PF05539.11 KII91576.1 - 1.6 8.2 5.5 1.7 8.2 5.5 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribosomal_L28 PF00830.19 KII91581.1 - 6.6e-21 74.3 2.3 1e-20 73.6 2.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family F-box-like PF12937.7 KII91582.1 - 2.8e-05 23.9 0.2 0.0001 22.1 0.2 2.1 1 0 0 1 1 1 1 F-box-like NT-C2 PF10358.9 KII91583.1 - 5.2e-18 65.2 0.0 1.2e-16 60.8 0.0 2.3 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins GWT1 PF06423.12 KII91585.1 - 7.1e-39 133.3 0.0 3.1e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 GWT1 DTHCT PF08070.11 KII91585.1 - 0.1 13.4 0.5 0.19 12.5 0.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region AA_permease_2 PF13520.6 KII91586.1 - 1.7e-54 185.3 52.0 2.1e-54 185.0 52.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII91586.1 - 1.1e-21 77.0 45.4 1.8e-21 76.3 45.4 1.2 1 0 0 1 1 1 1 Amino acid permease COX2-transmemb PF09125.10 KII91586.1 - 7.3 6.5 9.5 7 6.5 0.0 3.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane MCU PF04678.13 KII91587.1 - 6.3e-35 120.9 0.1 1.3e-34 119.8 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DIOX_N PF14226.6 KII91589.1 - 1.1e-18 68.1 0.0 2.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91589.1 - 4.2e-16 59.3 0.1 1.1e-15 57.9 0.0 1.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KII91590.1 - 8.5e-16 58.8 0.0 1.7e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91590.1 - 4.2e-13 49.7 0.0 9.4e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ZapC PF07126.12 KII91590.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Cell-division protein ZapC Peptidase_S10 PF00450.22 KII91592.1 - 9.1e-95 318.5 2.1 1.1e-94 318.3 2.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PhyH PF05721.13 KII91593.1 - 1.9e-10 41.4 0.0 3.4e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_5_C PF18564.1 KII91594.1 - 7.5e-24 84.1 0.2 1.4e-23 83.2 0.2 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KII91594.1 - 2.6e-13 50.1 0.0 2e-07 30.8 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) APH PF01636.23 KII91595.1 - 1e-13 51.8 0.1 6e-13 49.3 0.0 2.3 3 1 0 3 3 3 1 Phosphotransferase enzyme family Hexokinase_2 PF03727.16 KII91596.1 - 8.6e-83 277.4 0.0 1.2e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KII91596.1 - 1.1e-68 231.1 0.0 1.6e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ribosomal_L14 PF00238.19 KII91597.1 - 1.4e-44 151.1 2.7 1.6e-44 150.9 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Harakiri PF15196.6 KII91597.1 - 0.05 14.1 0.5 0.074 13.5 0.5 1.3 1 0 0 1 1 1 0 Activator of apoptosis harakiri BBS2_C PF14782.6 KII91597.1 - 0.11 11.2 0.7 3 6.5 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal WD40 PF00400.32 KII91598.1 - 1.6e-23 82.6 1.9 0.00013 22.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91598.1 - 4.9e-12 46.0 0.0 0.00041 20.6 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII91598.1 - 3.2e-05 23.9 0.0 0.07 13.0 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KII91598.1 - 0.0011 18.1 0.0 1.3 8.0 0.0 2.9 3 0 0 3 3 3 2 Coatomer WD associated region PD40 PF07676.12 KII91598.1 - 0.064 13.2 0.1 10 6.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KII91598.1 - 0.079 12.7 0.4 39 4.1 0.1 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ge1_WD40 PF16529.5 KII91598.1 - 0.11 11.4 0.1 18 4.2 0.0 3.0 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF-5_eIF-2B PF01873.17 KII91599.1 - 5.5e-41 139.1 0.1 9.5e-41 138.4 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KII91599.1 - 0.00044 19.7 0.2 0.00092 18.7 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 KII91599.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 KII91599.1 - 0.083 12.7 0.1 19 5.2 0.0 2.5 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KII91599.1 - 1.5 9.2 4.6 15 6.1 0.0 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain ATP-synt PF00231.19 KII91600.1 - 4.4e-81 272.7 1.8 5e-81 272.5 1.8 1.0 1 0 0 1 1 1 1 ATP synthase Glucosamine_iso PF01182.20 KII91601.1 - 2.3e-19 70.2 0.0 3.5e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 KII91601.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain UPF0029 PF01205.19 KII91602.1 - 2.4e-25 88.9 0.0 3.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 But2 PF09792.9 KII91603.1 - 4.6e-08 33.6 0.0 9.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Epimerase PF01370.21 KII91604.1 - 3.8e-17 62.6 0.0 2.8e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII91604.1 - 1.2e-12 48.1 0.4 1.8e-12 47.6 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII91604.1 - 1.1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KII91604.1 - 4.9e-11 42.2 0.0 6.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KII91604.1 - 2.8e-10 39.8 0.0 8.5e-09 35.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KII91604.1 - 4.1e-08 33.1 0.6 5.9e-08 32.6 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII91604.1 - 6.9e-06 25.4 0.0 9.2e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KII91604.1 - 7.6e-05 22.7 0.5 0.00018 21.5 0.5 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KII91604.1 - 0.00042 19.8 0.2 0.00066 19.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 KII91604.1 - 0.13 12.1 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MaoC_dehydratas PF01575.19 KII91605.1 - 1.1e-26 92.8 0.0 1.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KII91605.1 - 6.6e-06 26.3 0.0 0.0084 16.2 0.0 2.6 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase DUF3328 PF11807.8 KII91606.1 - 3.9e-24 85.7 0.0 4.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4227 PF14004.6 KII91606.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) HSP70 PF00012.20 KII91607.1 - 5.5e-39 133.8 0.0 6.5e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 KII91607.1 - 0.062 13.0 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FMO-like PF00743.19 KII91608.1 - 4.7e-21 74.8 0.0 1.4e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII91608.1 - 1.1e-18 67.5 0.0 8.5e-17 61.4 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII91608.1 - 3.6e-18 65.8 0.0 1.5e-09 37.5 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII91608.1 - 1.7e-14 53.8 0.0 6.7e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KII91608.1 - 1.6e-07 31.8 0.5 0.0029 18.1 0.0 3.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91608.1 - 3.7e-05 23.9 0.0 0.0018 18.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KII91608.1 - 0.0019 17.6 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 KII91608.1 - 0.0026 17.4 0.1 0.67 9.5 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KII91608.1 - 0.016 14.5 0.0 0.058 12.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KII91608.1 - 0.038 14.0 0.8 3.8 7.5 0.1 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding SnoaL_2 PF12680.7 KII91608.1 - 0.071 13.8 1.9 0.69 10.6 0.3 2.6 2 1 0 2 2 2 0 SnoaL-like domain Lycopene_cycl PF05834.12 KII91608.1 - 0.12 11.4 0.0 2 7.4 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein TauD PF02668.16 KII91609.1 - 4.8e-52 177.4 0.7 6.6e-52 176.9 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KII91609.1 - 6.3e-09 36.4 0.0 1.1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KII91609.1 - 6.2e-05 22.2 0.1 0.00012 21.3 0.1 1.4 1 1 0 1 1 1 1 CsiD Abhydrolase_1 PF00561.20 KII91610.1 - 7.3e-24 84.8 0.1 6e-23 81.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KII91610.1 - 7.5e-22 76.7 0.0 1.7e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KII91610.1 - 5.2e-05 22.6 0.1 0.0047 16.2 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KII91610.1 - 0.00062 19.5 0.0 0.058 13.1 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Kelch_6 PF13964.6 KII91611.1 - 1.3e-06 28.5 0.1 0.21 11.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 KII91611.1 - 0.00019 21.3 0.0 0.4 10.7 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 KII91611.1 - 0.00022 21.4 0.2 1.8 8.9 0.0 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 KII91611.1 - 0.0006 19.7 2.1 1.7 8.7 0.0 3.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 KII91611.1 - 0.0007 19.1 0.1 0.45 10.1 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KII91611.1 - 0.0024 17.8 0.1 26 4.9 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain FMO-like PF00743.19 KII91612.1 - 1e-20 73.7 0.0 3.7e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII91612.1 - 2.4e-17 63.1 0.0 3.6e-15 56.0 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII91612.1 - 4.5e-17 62.2 0.0 1e-08 34.8 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII91612.1 - 3.2e-14 52.8 0.0 3.2e-09 36.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KII91612.1 - 8.6e-08 32.6 0.1 0.0029 18.1 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91612.1 - 3.6e-05 23.9 0.0 0.0018 18.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII91612.1 - 0.00062 19.4 0.1 0.12 11.9 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KII91612.1 - 0.0017 17.7 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KII91612.1 - 0.0099 15.2 0.0 0.056 12.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KII91612.1 - 0.05 13.6 0.5 2.8 7.9 0.1 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KII91612.1 - 0.14 11.2 0.0 2.1 7.3 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 KII91612.1 - 0.2 10.3 0.0 1.7 7.2 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Nup54 PF13874.6 KII91613.1 - 1.2e-40 138.9 9.2 2.6e-40 137.8 9.2 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KII91613.1 - 2.7e-20 73.0 125.4 1.1e-09 39.0 47.4 4.0 2 1 2 4 4 3 3 Nucleoporin FG repeat region Nup54_C PF18437.1 KII91613.1 - 4.5e-07 29.7 3.0 4.5e-07 29.7 3.0 2.2 2 0 0 2 2 1 1 Nup54 C-terminal interacting domain TcdB_N PF12918.7 KII91613.1 - 0.077 13.3 0.3 0.27 11.5 0.3 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Troponin PF00992.20 KII91613.1 - 0.28 11.5 5.3 0.51 10.6 5.3 1.4 1 0 0 1 1 1 0 Troponin HWE_HK PF07536.14 KII91613.1 - 0.59 10.9 8.0 1.2 9.9 4.7 2.8 3 0 0 3 3 3 0 HWE histidine kinase DivIC PF04977.15 KII91613.1 - 0.86 9.4 3.6 0.53 10.1 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 KII91613.1 - 1 9.8 4.7 3.7 8.0 0.2 3.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 KII91613.1 - 2.2 6.7 7.3 4.2 5.8 7.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Uso1_p115_C PF04871.13 KII91613.1 - 3 8.2 8.5 11 6.4 8.6 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Baculo_PEP_C PF04513.12 KII91613.1 - 4.3 7.4 9.0 12 5.9 2.8 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KII91613.1 - 5.2 6.5 9.4 6 6.4 8.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fungal_trans PF04082.18 KII91614.1 - 2.6e-18 66.0 0.0 3.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91614.1 - 2.6e-08 33.9 10.2 5.1e-08 32.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 KII91614.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Pro_isomerase PF00160.21 KII91615.1 - 1.3e-44 152.3 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KII91615.1 - 0.00058 19.8 6.2 0.09 12.9 1.8 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII91615.1 - 0.52 10.2 4.3 2.8 7.9 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII91615.1 - 1.8 9.6 11.4 1.3 10.0 6.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII91615.1 - 2.8 8.8 6.4 95 4.0 1.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII91615.1 - 4 7.2 6.4 0.54 10.0 0.6 2.4 2 1 1 3 3 3 0 TPR repeat Exo_endo_phos PF03372.23 KII91616.1 - 3.6e-07 30.0 0.0 2e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 KII91616.1 - 2.6e-05 24.1 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.6 KII91616.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like HABP4_PAI-RBP1 PF04774.15 KII91617.1 - 0.002 19.0 2.3 0.0027 18.5 2.3 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family MMR_HSR1 PF01926.23 KII91619.1 - 6.9e-05 22.9 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KII91619.1 - 0.007 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KII91619.1 - 0.009 15.8 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KII91619.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KII91619.1 - 0.028 13.7 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Septin TniB PF05621.11 KII91619.1 - 0.04 13.3 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KII91619.1 - 0.044 12.9 0.0 0.87 8.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 KII91619.1 - 0.07 13.4 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KII91619.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KII91619.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 KII91619.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad51 BTB PF00651.31 KII91624.1 - 2.4e-06 27.7 0.0 3.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.7 KII91625.1 - 1.2e-06 29.4 1.2 2.1e-06 28.5 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KII91625.1 - 1.1e-05 25.6 0.1 4.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KII91625.1 - 3.4e-05 23.7 0.1 0.00026 20.8 0.1 2.1 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 KII91625.1 - 0.00015 21.2 0.0 0.00032 20.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII91625.1 - 0.002 17.9 0.6 0.017 14.8 0.4 2.7 3 1 0 3 3 3 1 alpha/beta hydrolase fold DUF676 PF05057.14 KII91625.1 - 0.0053 16.3 0.0 0.015 14.9 0.0 1.7 2 1 0 2 2 2 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 KII91625.1 - 0.0053 16.3 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF2048 PF09752.9 KII91625.1 - 0.0089 15.2 0.1 0.14 11.3 0.1 2.0 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Abhydrolase_3 PF07859.13 KII91625.1 - 0.065 13.1 0.1 0.21 11.4 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold UPF0227 PF05728.12 KII91625.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) NARP1 PF12569.8 KII91625.1 - 1.7 7.4 8.8 2.6 6.9 8.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EMC3_TMCO1 PF01956.16 KII91625.1 - 4.1 7.1 3.9 8.1 6.2 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TFIIS_C PF01096.18 KII91626.1 - 3.7e-12 45.9 1.3 3.7e-12 45.9 1.3 2.8 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KII91626.1 - 2.1e-11 43.5 1.0 2.1e-11 43.5 1.0 3.3 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 KII91626.1 - 0.00016 21.1 3.1 3 7.5 0.1 3.5 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 KII91626.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar RecR PF02132.15 KII91626.1 - 0.022 14.3 0.6 0.022 14.3 0.6 2.9 3 0 0 3 3 3 0 RecR protein GFA PF04828.14 KII91626.1 - 0.029 14.7 6.0 0.92 9.9 0.3 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KII91626.1 - 0.05 13.6 9.2 1.1 9.3 1.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 KII91626.1 - 0.065 13.1 0.6 0.065 13.1 0.6 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.13 KII91626.1 - 0.069 13.2 8.9 0.34 11.0 1.8 2.8 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.13 KII91626.1 - 0.089 12.5 0.3 0.089 12.5 0.3 2.8 4 0 0 4 4 3 0 InsA N-terminal domain zf-3CxxC PF13695.6 KII91626.1 - 0.12 12.8 2.9 1.5 9.3 1.0 2.2 2 0 0 2 2 2 0 Zinc-binding domain zinc_ribbon_2 PF13240.6 KII91626.1 - 0.13 12.0 8.8 1.5 8.6 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KII91626.1 - 0.16 12.0 5.6 0.76 9.8 0.1 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_9 PF14369.6 KII91626.1 - 0.27 11.5 7.7 4.3 7.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon DUF3268 PF11672.8 KII91626.1 - 0.28 11.5 4.0 0.3 11.4 0.1 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain eIF-5_eIF-2B PF01873.17 KII91626.1 - 0.48 10.3 6.4 1.5 8.8 0.6 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn-ribbon_8 PF09723.10 KII91626.1 - 0.79 9.9 8.1 9.2 6.5 0.1 3.5 4 0 0 4 4 4 0 Zinc ribbon domain UPF0547 PF10571.9 KII91626.1 - 0.81 9.8 0.0 0.81 9.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 KII91626.1 - 1.2 9.2 8.9 4.6 7.3 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KII91626.1 - 1.5 8.9 11.4 0.13 12.3 2.2 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-NADH-PPase PF09297.11 KII91626.1 - 3.1 7.5 7.3 4.2 7.1 0.2 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-ACC PF17848.1 KII91626.1 - 3.6 7.8 11.9 22 5.2 0.2 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain IBR PF01485.21 KII91626.1 - 3.7 7.8 10.4 6.3e+02 0.7 10.4 2.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DpnI PF06044.12 KII91626.1 - 3.9 7.1 7.0 0.89 9.2 0.3 2.0 2 0 0 2 2 2 0 Dam-replacing family Rpr2 PF04032.16 KII91626.1 - 5.4 7.4 8.7 59 4.0 8.7 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 KII91626.1 - 5.5 6.5 12.5 2 7.9 0.1 3.9 5 0 0 5 5 5 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KII91626.1 - 7.2 6.6 11.2 34 4.5 0.0 3.6 3 1 0 3 3 3 0 Nudix N-terminal Ribosomal_L27e PF01777.18 KII91627.1 - 3.5e-35 120.2 0.9 5e-35 119.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family PfkB PF00294.24 KII91628.1 - 3.5e-35 121.8 0.0 4.9e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4048 PF13257.6 KII91628.1 - 0.086 12.7 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Get5_C PF18514.1 KII91628.1 - 0.17 11.6 0.3 0.43 10.4 0.3 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain BTB PF00651.31 KII91629.1 - 3.2e-05 24.1 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_transf_22 PF03901.17 KII91630.1 - 8.7e-14 51.6 1.1 1.1e-13 51.2 1.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family NMN_transporter PF04973.12 KII91630.1 - 0.058 13.4 1.0 0.08 12.9 1.0 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Glyco_transf_22 PF03901.17 KII91631.1 - 1.1e-14 54.5 0.0 1.2e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Autophagy_N PF03986.13 KII91631.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Cyt-b5 PF00173.28 KII91632.1 - 7.5e-17 61.2 0.0 1.9e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KII91632.1 - 2.1e-11 44.3 16.8 2.1e-11 44.3 16.8 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF543 PF04418.12 KII91635.1 - 6.8e-29 99.7 0.1 7.6e-29 99.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) BRO1 PF03097.18 KII91636.1 - 4.8e-120 400.9 0.1 7.6e-120 400.3 0.1 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KII91636.1 - 3.8e-60 203.7 2.9 5.5e-60 203.2 2.9 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MMR_HSR1 PF01926.23 KII91637.1 - 1.1e-05 25.4 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KII91637.1 - 7.2e-05 22.2 0.1 0.00063 19.1 0.1 2.1 1 1 0 1 1 1 1 Septin ABC_tran PF00005.27 KII91637.1 - 0.00086 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KII91637.1 - 0.0011 19.0 0.0 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KII91637.1 - 0.0011 19.4 0.0 0.0035 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KII91637.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KII91637.1 - 0.014 15.6 0.0 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KII91637.1 - 0.016 15.0 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 KII91637.1 - 0.016 14.8 0.1 0.18 11.4 0.1 2.3 1 1 0 1 1 1 0 Ras family AAA_21 PF13304.6 KII91637.1 - 0.022 14.6 0.1 0.05 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 KII91637.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KII91637.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KII91637.1 - 0.082 13.0 0.7 0.26 11.3 0.7 1.8 1 1 0 1 1 1 0 Dynamin family G-alpha PF00503.20 KII91637.1 - 0.085 12.0 0.1 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KII91637.1 - 0.087 12.2 0.2 0.83 9.0 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MCM PF00493.23 KII91637.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_15 PF13175.6 KII91637.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 KII91637.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KII91637.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AIG1 PF04548.16 KII91637.1 - 0.11 11.8 0.3 0.19 11.0 0.3 1.5 1 1 0 1 1 1 0 AIG1 family AAA_7 PF12775.7 KII91637.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KII91637.1 - 0.15 12.5 0.0 0.74 10.2 0.0 2.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KII91637.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KII91637.1 - 0.2 10.8 0.1 0.69 9.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain PNP_UDP_1 PF01048.20 KII91639.1 - 1.6e-36 125.7 0.3 2.4e-36 125.1 0.3 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily 2OG-FeII_Oxy_3 PF13640.6 KII91641.1 - 3.6e-11 43.8 0.1 6.2e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 KII91641.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein Zn_ribbon_17 PF17120.5 KII91642.1 - 6.4e-06 25.7 3.4 6.4e-06 25.7 3.4 3.0 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KII91642.1 - 0.0026 18.6 18.4 0.21 12.5 0.4 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Zf_RING PF16744.5 KII91642.1 - 0.0055 16.8 0.9 0.0055 16.8 0.9 2.2 2 0 0 2 2 2 1 KIAA1045 RING finger PHD PF00628.29 KII91642.1 - 0.066 13.1 7.3 0.53 10.2 4.0 2.6 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KII91642.1 - 0.18 11.9 6.1 1.2 9.2 4.3 2.5 2 0 0 2 2 2 0 PHD-finger RecR PF02132.15 KII91642.1 - 1.9 8.1 7.9 0.14 11.8 2.1 2.0 2 0 0 2 2 2 0 RecR protein FMO-like PF00743.19 KII91643.1 - 1e-22 80.3 0.0 1.5e-10 40.2 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KII91643.1 - 8.1e-11 41.7 0.0 2.8e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII91643.1 - 1.7e-09 37.4 0.0 1.4e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91643.1 - 3e-06 27.4 0.1 1.2e-05 25.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KII91643.1 - 0.00083 19.0 0.0 0.0021 17.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII91643.1 - 0.0013 18.8 0.1 0.0058 16.6 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KII91643.1 - 0.0023 17.2 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KII91643.1 - 0.0024 16.6 0.0 0.0053 15.5 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KII91643.1 - 0.0035 16.7 0.0 0.018 14.3 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KII91643.1 - 0.006 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KII91643.1 - 0.0078 15.4 0.4 0.15 11.2 0.0 2.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 KII91643.1 - 0.027 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KII91643.1 - 0.15 11.4 0.1 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rap1-DNA-bind PF09197.10 KII91644.1 - 0.00042 20.9 8.3 0.021 15.4 0.0 3.6 3 1 0 3 3 3 2 Rap1, DNA-binding Myb_DNA-bind_2 PF08914.11 KII91644.1 - 0.0013 18.8 5.0 1.7 8.8 0.2 3.4 3 0 0 3 3 3 3 Rap1 Myb domain CENP-B_dimeris PF09026.10 KII91644.1 - 0.06 13.7 1.7 0.15 12.5 1.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Iso_dh PF00180.20 KII91645.1 - 1.3e-71 241.6 0.0 1.6e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 KII91646.1 - 3.8e-13 49.1 12.0 2.1e-12 46.6 12.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.6 KII91647.1 - 7.4e-10 39.6 0.1 1.4e-09 38.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Git3 PF11710.8 KII91648.1 - 1.2e-09 38.2 6.2 2.3e-09 37.4 6.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KII91648.1 - 0.00096 18.5 3.5 0.0014 18.0 3.1 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KII91648.1 - 0.0017 18.4 1.7 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term AAA_5 PF07728.14 KII91649.1 - 1.2e-68 229.4 0.0 1.2e-28 99.9 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII91649.1 - 0.00038 20.9 0.2 2.2 8.6 0.0 3.9 3 1 1 4 4 4 2 AAA ATPase domain CbbQ_C PF08406.10 KII91649.1 - 0.0074 16.5 0.1 5.2 7.4 0.1 2.6 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 KII91649.1 - 0.16 12.4 0.0 0.94 9.9 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sof1 PF04158.14 KII91650.1 - 4.8e-29 100.5 9.0 1.1e-28 99.3 9.0 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KII91650.1 - 1.2e-24 86.1 11.5 4.1e-07 30.6 0.2 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII91650.1 - 4.4e-06 26.9 0.1 4.2 7.7 0.0 4.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII91650.1 - 0.011 15.6 0.0 0.076 12.9 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Vps26 PF03643.15 KII91652.1 - 2.4e-128 426.9 2.4 2.8e-128 426.7 2.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KII91652.1 - 0.12 12.4 0.6 4.2 7.4 0.1 3.0 2 1 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Sds3 PF08598.11 KII91653.1 - 8.6e-23 81.5 0.4 5.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Sds3-like Plus-3 PF03126.18 KII91654.1 - 8.9e-34 116.3 0.0 2.2e-32 111.8 0.0 2.8 2 0 0 2 2 2 1 Plus-3 domain HTH_57 PF18679.1 KII91654.1 - 0.26 11.6 1.6 0.28 11.5 0.1 1.8 2 0 0 2 2 2 0 ThcOx helix turn helix domain Caldesmon PF02029.15 KII91654.1 - 4.3 6.0 41.9 26 3.4 42.3 1.8 1 1 1 2 2 2 0 Caldesmon F-box PF00646.33 KII91655.1 - 5.9e-07 29.2 1.9 0.00036 20.3 0.0 3.7 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KII91655.1 - 4.4e-06 26.5 0.2 2.9e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF3760 PF12586.8 KII91655.1 - 0.012 15.8 0.0 0.069 13.3 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Peroxin-22 PF12827.7 KII91655.1 - 0.17 11.9 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF2013 PF09431.10 KII91657.1 - 3e-56 189.4 0.2 3e-56 189.4 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Abhydrolase_3 PF07859.13 KII91658.1 - 1.5e-14 54.4 0.4 1.8e-13 50.8 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII91658.1 - 1.9e-07 30.3 0.0 6.6e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KII91658.1 - 0.0042 16.0 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KII91658.1 - 0.059 12.8 0.0 0.38 10.2 0.0 2.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Epimerase PF01370.21 KII91658.1 - 0.095 12.1 0.0 7.8 5.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Hydrolase_4 PF12146.8 KII91658.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KII91659.1 - 3.9e-75 252.6 0.0 5.9e-75 252.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91659.1 - 9.1e-34 116.9 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII91659.1 - 2.8e-06 26.9 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII91659.1 - 8.7e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII91659.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII91659.1 - 0.0039 17.1 0.0 0.031 14.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Gti1_Pac2 PF09729.9 KII91662.1 - 1.9e-43 148.7 0.1 1e-35 123.5 0.1 2.5 2 0 0 2 2 2 2 Gti1/Pac2 family MIP PF00230.20 KII91664.1 - 1.4e-54 185.2 5.9 1.7e-54 185.0 5.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_6 PF08030.12 KII91666.1 - 3.9e-36 124.5 0.0 7e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII91666.1 - 1.5e-23 83.0 0.0 3.5e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KII91666.1 - 2.3e-17 63.3 15.5 5e-17 62.2 8.7 2.4 2 0 0 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KII91666.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_28 PF00295.17 KII91667.1 - 1.4e-41 142.6 0.4 2.6e-41 141.7 0.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Methyltransf_3 PF01596.17 KII91669.1 - 3.2e-36 124.5 0.0 4.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KII91669.1 - 5.6e-17 62.7 0.0 9.4e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII91669.1 - 1.9e-07 31.1 0.1 2.6e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KII91669.1 - 6.7e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII91669.1 - 0.00021 21.9 0.0 0.00058 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII91669.1 - 0.0015 19.1 0.0 0.0041 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KII91669.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.17 KII91671.1 - 6.1e-37 126.9 0.0 7.5e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KII91671.1 - 8.8e-16 58.9 0.0 1.4e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII91671.1 - 1.2e-06 28.4 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KII91671.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII91671.1 - 2.6e-05 24.8 0.0 5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KII91671.1 - 0.00056 19.3 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KII91671.1 - 0.0035 18.0 0.1 0.012 16.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KII91671.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.10 KII91671.1 - 0.019 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 KII91671.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_4 PF08386.10 KII91672.1 - 5.8e-20 71.3 0.1 1.6e-19 69.9 0.1 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KII91672.1 - 5.1e-19 68.9 0.1 5.1e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold VIT1 PF01988.19 KII91673.1 - 3.4e-63 213.4 7.5 4e-63 213.2 7.5 1.0 1 0 0 1 1 1 1 VIT family ThiF PF00899.21 KII91674.1 - 2.2e-41 141.8 0.0 3.6e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KII91674.1 - 3.5e-06 27.3 0.2 2.3e-05 24.6 0.2 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KII91674.1 - 0.00048 20.5 0.1 0.00095 19.6 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KII91674.1 - 0.0032 17.1 0.1 0.0056 16.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KII91674.1 - 0.0096 15.5 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 KII91674.1 - 0.02 14.6 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KII91674.1 - 0.023 14.6 0.1 0.045 13.6 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KII91674.1 - 0.023 14.0 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KII91674.1 - 0.025 13.8 0.3 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KII91674.1 - 0.093 13.0 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain MTS PF05175.14 KII91674.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TraE PF05309.11 KII91675.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 TraE protein Yip1 PF04893.17 KII91676.1 - 2.9e-07 30.4 23.1 4.4e-07 29.8 23.1 1.4 1 0 0 1 1 1 1 Yip1 domain Peroxidase_2 PF01328.17 KII91677.1 - 1.5e-48 165.8 0.0 2.2e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 ADH_N PF08240.12 KII91678.1 - 2.2e-26 91.9 0.6 3.9e-26 91.1 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII91678.1 - 1.1e-22 80.3 0.1 1.9e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII91678.1 - 6.9e-10 38.8 0.7 1.1e-09 38.2 0.7 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII91678.1 - 0.00044 21.3 0.1 0.00071 20.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KII91678.1 - 0.0073 16.2 0.5 0.022 14.7 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.20 KII91678.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amidase PF01425.21 KII91679.1 - 5.4e-75 253.1 0.0 2e-73 247.9 0.0 2.0 1 1 0 1 1 1 1 Amidase EBV-NA1 PF02905.14 KII91680.1 - 0.61 9.9 2.9 0.36 10.6 0.3 1.7 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain zf-C3HC4_3 PF13920.6 KII91681.1 - 3.8e-11 42.7 14.9 3.1e-07 30.2 6.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KII91681.1 - 1.8e-10 40.6 1.7 5.3e-06 26.0 0.2 2.4 2 0 0 2 2 2 2 Rtf2 RING-finger zf-NOSIP PF15906.5 KII91681.1 - 1.3e-09 38.0 0.3 1.3e-09 38.0 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 KII91681.1 - 3.5e-07 30.4 15.8 7.8e-05 22.9 8.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 KII91681.1 - 8e-07 28.8 18.2 0.00024 20.9 9.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII91681.1 - 1.7e-06 27.9 12.8 0.0084 16.1 5.6 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KII91681.1 - 3.6e-05 23.5 17.8 0.013 15.3 8.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII91681.1 - 6.6e-05 22.8 7.2 6.6e-05 22.8 7.2 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII91681.1 - 0.0002 21.2 19.1 0.0025 17.6 3.4 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KII91681.1 - 0.015 15.4 14.5 0.67 10.2 0.8 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KII91681.1 - 0.04 14.0 9.7 0.06 13.5 2.5 2.7 2 1 0 2 2 2 0 FYVE zinc finger TackOD1 PF18551.1 KII91681.1 - 1.7 8.3 13.3 0.043 13.5 4.6 2.2 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 MRP-L20 PF12824.7 KII91681.1 - 2 8.5 6.0 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 zinc-ribbons_6 PF07191.12 KII91681.1 - 2.4 8.2 14.4 2.7 8.0 5.6 2.4 2 0 0 2 2 2 0 zinc-ribbons Siva PF05458.12 KII91681.1 - 2.7 7.6 9.4 0.25 11.0 3.0 2.1 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Elf1 PF05129.13 KII91681.1 - 7.3 6.7 9.5 0.92 9.6 4.0 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 KII91681.1 - 9.8 6.3 15.7 5.6 7.1 7.0 2.9 2 1 0 2 2 2 0 Double zinc ribbon Glyco_hydro_31 PF01055.26 KII91682.1 - 5.1e-86 289.6 2.2 7.7e-86 289.0 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KII91682.1 - 0.061 13.6 0.0 0.34 11.3 0.0 2.2 1 1 0 1 1 1 0 Galactose mutarotase-like SWC7 PF17330.2 KII91683.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 DUF4628 PF15429.6 KII91683.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Thaumatin PF00314.17 KII91684.1 - 2.1e-68 230.2 5.8 2.4e-68 230.0 5.8 1.0 1 0 0 1 1 1 1 Thaumatin family SYF2 PF08231.12 KII91685.1 - 6.1e-62 208.7 8.6 6.1e-62 208.7 8.6 1.9 2 0 0 2 2 2 1 SYF2 splicing factor Pkinase PF00069.25 KII91686.1 - 3.3e-19 69.3 0.0 3.8e-18 65.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91686.1 - 1.4e-09 37.6 0.0 1.8e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase MgtE PF01769.16 KII91686.1 - 0.044 14.2 0.7 0.078 13.4 0.7 1.3 1 0 0 1 1 1 0 Divalent cation transporter RXLR PF16810.5 KII91686.1 - 0.073 13.5 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity RIO1 PF01163.22 KII91686.1 - 0.11 12.1 0.6 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pyr_redox_2 PF07992.14 KII91687.1 - 7e-42 143.7 0.0 8.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII91687.1 - 3.5e-11 43.5 0.0 1.5e-08 35.1 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII91687.1 - 0.0098 15.2 0.1 1.2 8.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CytB6-F_Fe-S PF08802.10 KII91687.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit MFS_1 PF07690.16 KII91689.1 - 7.7e-35 120.4 34.4 1.2e-34 119.9 34.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII91690.1 - 1.5e-84 284.4 27.4 2e-84 284.1 27.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII91690.1 - 2.4e-20 72.8 76.1 1.2e-14 54.1 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI-anchored PF10342.9 KII91691.1 - 4.4e-09 37.0 3.1 4.4e-09 37.0 3.1 2.2 1 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family APC1_C PF18122.1 KII91692.1 - 2.6e-30 105.6 0.1 6.8e-30 104.2 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KII91692.1 - 8.4e-06 26.4 0.0 0.00021 21.8 0.0 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KII91692.1 - 0.00054 20.3 15.3 0.29 11.6 0.0 5.6 6 0 0 6 6 6 4 Proteasome/cyclosome repeat MCM PF00493.23 KII91693.1 - 7.2e-97 322.9 0.0 1.1e-96 322.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KII91693.1 - 1.5e-35 121.8 0.3 2.6e-35 121.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KII91693.1 - 9.8e-28 96.4 1.1 1.9e-27 95.5 1.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KII91693.1 - 3.2e-15 56.6 0.0 8.9e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KII91693.1 - 5.6e-08 32.9 0.0 1.7e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KII91693.1 - 2.8e-07 30.1 0.0 9.1e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KII91693.1 - 0.00013 21.8 0.0 0.0039 17.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KII91693.1 - 0.0015 18.2 0.1 1.1 8.9 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 KII91693.1 - 0.0054 17.1 0.2 0.067 13.6 0.2 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 KII91693.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APH PF01636.23 KII91694.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAM196 PF15265.6 KII91697.1 - 2.8 7.3 6.5 0.2 11.2 1.2 1.7 2 0 0 2 2 2 0 FAM196 family DAO PF01266.24 KII91698.1 - 5.1e-65 220.4 2.2 5.9e-65 220.1 2.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KII91698.1 - 1.1e-06 28.1 0.1 0.0088 15.3 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII91698.1 - 4.6e-06 26.8 0.6 1.9e-05 24.8 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KII91698.1 - 0.00019 20.4 0.1 0.013 14.4 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 KII91698.1 - 0.0015 19.1 0.2 0.0075 16.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII91698.1 - 0.0036 17.3 0.5 0.39 10.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KII91698.1 - 0.0045 16.4 0.1 0.64 9.3 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase GIDA PF01134.22 KII91698.1 - 0.009 15.1 0.0 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KII91698.1 - 0.016 14.5 0.3 0.027 13.7 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Sacchrp_dh_NADP PF03435.18 KII91698.1 - 0.016 15.4 0.2 0.039 14.2 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 KII91699.1 - 1.2e-16 60.9 0.0 4.8e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KII91699.1 - 1.1e-14 54.5 18.3 8.1e-08 32.8 0.8 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.22 KII91699.1 - 4.3e-11 42.1 12.7 0.16 12.3 0.1 6.4 6 0 0 6 6 6 5 HEAT repeat Pkinase_Tyr PF07714.17 KII91699.1 - 6.4e-07 28.9 0.0 9.2e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KII91699.1 - 3.3e-06 27.4 0.3 0.45 10.9 0.0 4.6 3 1 2 5 5 5 3 HEAT repeats Cohesin_HEAT PF12765.7 KII91699.1 - 0.018 15.3 5.8 0.051 13.9 0.2 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KII91699.1 - 0.034 14.2 8.2 9.6 6.2 0.8 4.1 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KII91699.1 - 0.13 12.9 1.5 2.7 8.7 0.1 2.8 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KII91699.1 - 0.26 11.8 4.3 28 5.3 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat zf-MYND PF01753.18 KII91700.1 - 6.2e-09 35.8 11.6 6.2e-09 35.8 11.6 1.7 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KII91700.1 - 0.23 11.8 9.3 0.56 10.6 9.4 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KII91700.1 - 0.91 9.7 5.5 3.5 7.8 5.5 1.9 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KII91700.1 - 1.2 9.1 8.4 3.7 7.5 8.4 1.9 1 1 0 1 1 1 0 HIT zinc finger Asp_protease_2 PF13650.6 KII91701.1 - 6.2e-05 23.6 0.0 0.00038 21.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KII91701.1 - 0.00014 22.4 0.0 0.00092 19.7 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Yip1 PF04893.17 KII91702.1 - 5.1e-07 29.6 8.7 5.8e-07 29.4 8.7 1.1 1 0 0 1 1 1 1 Yip1 domain SET PF00856.28 KII91704.1 - 1.1e-11 45.4 0.2 2.6e-10 40.9 0.2 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KII91705.1 - 4.8e-09 36.2 12.3 8.6e-09 35.3 12.3 1.4 1 0 0 1 1 1 1 MYND finger DNApol3-delta_C PF09115.10 KII91705.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal zf-C6H2 PF15801.5 KII91705.1 - 1 9.7 9.4 2 8.8 9.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KII91705.1 - 2.6 8.2 7.7 0.94 9.6 3.0 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 UcrQ PF02939.16 KII91707.1 - 1.1e-32 111.7 2.0 1.3e-32 111.5 2.0 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 KII91707.1 - 0.00045 20.6 0.0 0.00057 20.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 MFS_1 PF07690.16 KII91708.1 - 3.8e-37 128.0 71.0 1.5e-27 96.4 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KII91708.1 - 7.3e-09 34.7 27.5 2.1e-06 26.6 9.8 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein YwiC PF14256.6 KII91708.1 - 0.29 11.5 0.0 0.29 11.5 0.0 3.9 2 2 2 4 4 4 0 YwiC-like protein NAD_binding_4 PF07993.12 KII91709.1 - 6.4e-32 110.7 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KII91709.1 - 2e-28 99.2 0.0 7e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KII91709.1 - 2.7e-07 30.3 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KII91709.1 - 0.00029 21.1 0.0 0.00078 19.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KII91709.1 - 0.0059 16.5 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KII91709.1 - 0.064 12.4 0.0 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SNF5 PF04855.12 KII91710.1 - 3e-65 220.3 0.3 5.5e-65 219.5 0.3 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KII91710.1 - 0.045 13.4 2.3 0.092 12.4 2.3 1.6 1 0 0 1 1 1 0 GATA zinc finger AAA_11 PF13086.6 KII91711.1 - 8.9e-63 212.5 0.0 1.8e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KII91711.1 - 4.5e-57 192.9 0.0 7.4e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KII91711.1 - 5.9e-10 39.2 0.0 1.2e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KII91711.1 - 1.2e-09 38.2 0.1 0.011 15.4 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KII91711.1 - 8e-09 36.0 0.0 1.9e-07 31.5 0.0 3.0 2 2 0 2 2 2 1 AAA domain ResIII PF04851.15 KII91711.1 - 0.0012 18.9 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KII91711.1 - 0.0015 18.8 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KII91711.1 - 0.0029 17.4 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 KII91711.1 - 0.0096 15.2 0.0 0.9 8.7 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KII91711.1 - 0.01 15.4 0.0 0.068 12.7 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.29 KII91711.1 - 0.014 15.8 0.0 0.053 13.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII91711.1 - 0.018 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KII91711.1 - 0.039 14.5 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KII91711.1 - 0.054 12.7 0.0 9.6 5.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.27 KII91711.1 - 0.06 13.9 0.0 1.1 9.7 0.0 2.6 1 1 1 2 2 2 0 ABC transporter AAA_33 PF13671.6 KII91711.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AF-4 PF05110.13 KII91711.1 - 0.94 7.5 13.2 1.4 6.9 13.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ATPase_2 PF01637.18 KII91712.1 - 3.1e-11 43.6 0.0 0.00016 21.7 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KII91712.1 - 4e-06 27.3 0.2 1.5e-05 25.5 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII91712.1 - 0.00083 19.6 0.3 0.54 10.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KII91712.1 - 0.011 16.1 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KII91712.1 - 0.064 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA12 PF10443.9 KII91712.1 - 0.19 10.4 0.0 0.41 9.3 0.0 1.5 2 0 0 2 2 2 0 RNA12 protein zf-C3HC4_3 PF13920.6 KII91714.1 - 2.7e-07 30.3 4.4 2.7e-07 30.3 4.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII91714.1 - 5.1e-07 29.5 5.8 5.1e-07 29.5 5.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII91714.1 - 7.5e-07 28.9 1.6 7.5e-07 28.9 1.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII91714.1 - 1.9e-06 27.8 2.2 1.9e-06 27.8 2.2 2.1 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KII91714.1 - 1.2e-05 25.1 4.7 1.2e-05 25.1 4.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII91714.1 - 6.1e-05 23.3 6.8 6.1e-05 23.3 6.8 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 KII91714.1 - 0.00012 22.2 4.1 0.00012 22.2 4.1 2.8 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KII91714.1 - 0.001 18.9 0.1 0.001 18.9 0.1 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KII91714.1 - 0.0016 18.2 3.3 0.0016 18.2 3.3 2.3 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KII91714.1 - 0.019 14.6 0.8 0.019 14.6 0.8 2.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Pellino PF04710.14 KII91714.1 - 0.093 11.4 1.0 0.15 10.7 1.0 1.2 1 0 0 1 1 1 0 Pellino zf-RING_10 PF16685.5 KII91714.1 - 0.15 12.2 1.6 0.36 11.0 1.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 GAGA PF09237.11 KII91714.1 - 0.15 11.9 0.9 9.8 6.1 0.1 2.7 2 0 0 2 2 2 0 GAGA factor zf-rbx1 PF12678.7 KII91714.1 - 0.35 11.2 4.1 1 9.7 4.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 KII91714.1 - 0.36 11.3 3.1 0.18 12.3 0.8 1.7 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 Macoilin PF09726.9 KII91714.1 - 1.2 7.6 12.1 1.9 6.9 12.1 1.2 1 0 0 1 1 1 0 Macoilin family DZR PF12773.7 KII91714.1 - 4.1 7.5 10.3 31 4.7 0.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-UBR PF02207.20 KII91714.1 - 7.1 6.9 8.9 0.75 10.0 1.1 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TPT PF03151.16 KII91715.1 - 1.1e-36 126.7 10.2 2.1e-36 125.7 10.2 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KII91715.1 - 1e-06 28.9 26.6 0.00097 19.3 10.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KII91715.1 - 1.3e-05 24.5 16.8 0.00024 20.4 16.8 2.2 1 1 0 1 1 1 1 UAA transporter family YtpI PF14007.6 KII91715.1 - 1.1 9.5 16.8 1.4 9.1 0.2 4.1 4 1 1 5 5 5 0 YtpI-like protein RHH_1 PF01402.21 KII91716.1 - 0.07 13.1 0.8 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HTH_50 PF18024.1 KII91716.1 - 0.13 11.8 0.2 0.36 10.5 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 KII91716.1 - 0.19 11.6 2.4 1.1 9.1 0.2 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Peptidase_S41 PF03572.18 KII91717.1 - 3.3e-06 26.8 0.0 1.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 Pyr_redox_2 PF07992.14 KII91717.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 KII91718.1 - 4e-12 47.2 2.4 4e-12 47.2 2.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII91718.1 - 0.0014 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KII91718.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KII91718.1 - 0.037 12.5 0.0 0.25 9.8 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KII91718.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LEA_5 PF00477.17 KII91719.1 - 0.056 13.9 1.5 0.074 13.5 1.5 1.1 1 0 0 1 1 1 0 Small hydrophilic plant seed protein DUF1308 PF07000.11 KII91720.1 - 2.8e-05 24.1 0.1 0.67 9.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) DUF2267 PF10025.9 KII91720.1 - 0.054 13.8 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Abhydrolase_6 PF12697.7 KII91721.1 - 0.00083 20.0 0.3 0.00083 20.0 0.3 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII91721.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII91721.1 - 0.054 12.7 0.1 0.086 12.1 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KII91721.1 - 0.13 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Putative esterase SSF PF00474.17 KII91723.1 - 1.1e-20 74.0 31.2 1.8e-20 73.2 31.2 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DIOX_N PF14226.6 KII91724.1 - 7.9e-13 49.2 0.0 1.4e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII91724.1 - 2.8e-12 47.0 0.1 7.8e-12 45.6 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SET PF00856.28 KII91726.1 - 1.2e-20 74.6 0.6 7.5e-20 72.0 0.1 2.3 2 1 0 2 2 2 1 SET domain N-SET PF11764.8 KII91726.1 - 1.6e-10 41.4 5.7 2e-08 34.5 4.2 3.1 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N O-FucT PF10250.9 KII91727.1 - 5e-16 59.3 0.0 2.2e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.7 KII91728.1 - 0.00014 21.7 3.6 0.0053 16.6 1.9 2.9 2 0 0 2 2 2 2 F-box-like hemP PF10636.9 KII91728.1 - 0.14 12.0 0.2 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 Hemin uptake protein hemP Abhydrolase_6 PF12697.7 KII91729.1 - 1.1e-09 39.2 0.0 1.5e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII91729.1 - 5.9e-07 29.0 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII91729.1 - 1.7e-06 27.8 0.1 4e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold O-FucT PF10250.9 KII91730.1 - 6.6e-14 52.3 0.0 1.3e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Aldedh PF00171.22 KII91733.1 - 3e-129 431.5 0.0 3.6e-129 431.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KII91733.1 - 0.0086 16.1 0.2 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated WD40 PF00400.32 KII91734.1 - 1.1e-08 35.6 5.3 0.053 14.4 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4394 PF14339.6 KII91734.1 - 0.00097 18.6 0.0 0.0024 17.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4394) SGL PF08450.12 KII91734.1 - 0.0073 15.9 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 KII91734.1 - 0.07 13.4 0.0 9 6.7 0.0 3.2 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII91734.1 - 0.091 12.1 0.1 0.2 11.0 0.1 1.5 1 1 0 1 1 1 0 WD40-like domain PHTB1_N PF14727.6 KII91734.1 - 0.17 11.2 0.1 5.7 6.2 0.1 2.5 2 1 1 3 3 3 0 PTHB1 N-terminus Nop14 PF04147.12 KII91734.1 - 1.3 7.1 16.3 1.8 6.7 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KII91734.1 - 8.7 4.5 15.8 12 4.0 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribonuc_2-5A PF06479.12 KII91735.1 - 5.8e-45 152.6 0.1 9.9e-45 151.8 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 KII91735.1 - 2.6e-38 131.9 0.0 1.5e-30 106.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII91735.1 - 3.9e-19 69.0 0.0 1.8e-18 66.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII91735.1 - 5.4e-05 22.1 0.0 8.8e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PQQ PF01011.21 KII91735.1 - 0.00026 20.8 0.0 0.0097 15.8 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 KII91735.1 - 0.00098 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 KII91735.1 - 0.002 17.8 0.7 0.0067 16.0 0.0 2.2 3 0 0 3 3 3 1 PQQ-like domain APH PF01636.23 KII91735.1 - 0.07 13.0 0.1 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Thr_synth_N PF14821.6 KII91736.1 - 2.4e-25 88.6 0.0 6.4e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KII91736.1 - 2.6e-16 59.9 0.0 7.6e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2b PF00587.25 KII91737.1 - 1.6e-37 129.3 0.1 3.4e-37 128.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KII91737.1 - 3.6e-20 72.2 5.6 3.6e-20 72.2 5.6 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.32 KII91739.1 - 2.8e-36 122.9 19.8 4.1e-07 30.6 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KII91739.1 - 8e-08 32.1 1.0 1.5e-07 31.1 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII91739.1 - 3.8e-07 29.8 0.3 8.3e-07 28.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KII91739.1 - 1.5e-06 27.2 1.4 0.4 9.3 0.0 4.2 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII91739.1 - 1.8e-06 28.2 0.1 0.0072 16.6 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 KII91739.1 - 0.0098 14.7 0.1 6.9 5.3 0.0 4.0 3 2 1 4 4 4 2 Nup133 N terminal like Endostatin PF06482.11 KII91740.1 - 7.1 6.0 6.6 11 5.4 6.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Glyco_hyd_65N_2 PF14498.6 KII91742.1 - 5.2e-42 144.3 0.3 1e-41 143.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STAG PF08514.11 KII91743.1 - 5.4e-37 126.2 0.3 2.4e-36 124.1 0.2 2.3 1 1 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 KII91743.1 - 1.5e-07 31.7 2.0 0.008 16.5 0.0 3.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KII91743.1 - 1.4e-06 28.1 0.0 1.9 9.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat MFMR_assoc PF16596.5 KII91743.1 - 0.019 15.4 0.7 0.019 15.4 0.7 3.8 4 1 0 4 4 4 0 Disordered region downstream of MFMR GAS PF13851.6 KII91744.1 - 0.00015 21.2 0.8 0.00027 20.4 0.8 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KII91744.1 - 0.0066 15.4 1.3 0.0088 15.0 1.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KII91744.1 - 0.0086 16.3 4.5 1.1 9.5 0.6 2.4 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 KII91744.1 - 0.017 14.9 3.1 0.027 14.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Alpha-2-MRAP_C PF06401.11 KII91744.1 - 0.034 14.1 0.7 0.053 13.5 0.7 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Spc24 PF08286.11 KII91744.1 - 0.05 13.8 4.6 12 6.2 1.3 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 STAT_alpha PF01017.20 KII91744.1 - 0.056 13.3 2.1 0.091 12.6 2.1 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain HAP1_N PF04849.13 KII91744.1 - 0.058 12.6 5.2 0.31 10.2 5.2 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Bap31_Bap29_C PF18035.1 KII91744.1 - 0.059 13.4 2.2 1.9 8.5 0.1 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain HalX PF08663.10 KII91744.1 - 0.23 11.8 5.8 4.4 7.7 0.6 2.4 2 0 0 2 2 2 0 HalX domain HIP1_clath_bdg PF16515.5 KII91744.1 - 0.24 12.0 5.0 0.69 10.6 5.0 1.8 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 KII91744.1 - 0.33 11.1 5.2 0.46 10.6 0.8 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 KII91744.1 - 0.44 9.0 9.4 0.69 8.4 9.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.6 KII91744.1 - 0.57 10.3 4.9 1.2 9.2 4.9 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FlgN PF05130.12 KII91744.1 - 0.58 10.7 5.7 1.9 9.0 0.5 1.9 1 1 1 2 2 2 0 FlgN protein KELK PF15796.5 KII91744.1 - 0.75 10.3 2.9 12 6.4 0.2 2.4 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ZapB PF06005.12 KII91744.1 - 0.77 10.3 7.0 9.3 6.8 0.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 KII91744.1 - 0.89 9.8 4.8 12 6.2 0.2 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 KII91744.1 - 0.92 10.2 2.7 8.6 7.1 2.7 2.2 1 1 0 1 1 1 0 Initiation control protein YabA GvpK PF05121.12 KII91744.1 - 1.5 8.9 4.4 0.89 9.6 0.8 2.1 1 1 1 2 2 2 0 Gas vesicle protein K Sec34 PF04136.15 KII91744.1 - 1.5 8.7 4.6 12 5.8 0.5 2.4 1 1 1 2 2 2 0 Sec34-like family APG6_N PF17675.1 KII91744.1 - 4.4 7.8 9.7 9.4 6.8 1.2 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KII91744.1 - 6.3 6.6 7.2 17 5.2 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 KII91744.1 - 8.8 6.5 14.9 1.7 8.8 8.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Serglycin PF04360.12 KII91745.1 - 0.0094 15.9 1.0 0.022 14.7 1.0 1.7 1 0 0 1 1 1 1 Serglycin DUF3292 PF11696.8 KII91746.1 - 3.1e-82 277.0 0.0 8.3e-82 275.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) DUF3293 PF11697.8 KII91746.1 - 0.00029 21.2 0.4 0.0014 19.1 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3293) BBP1_C PF15272.6 KII91747.1 - 0.083 12.7 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Pkinase PF00069.25 KII91748.1 - 2.4e-35 122.2 0.0 4e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91748.1 - 2.6e-09 36.8 0.0 4.1e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII91748.1 - 5.1e-06 26.0 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KII91748.1 - 0.0027 16.8 0.1 0.0056 15.8 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KII91748.1 - 0.0068 16.3 0.1 0.03 14.2 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII91748.1 - 0.0075 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Urm1 PF09138.11 KII91750.1 - 1.4e-33 115.1 0.1 1.4e-31 108.7 0.1 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KII91750.1 - 8.6e-06 26.3 0.0 1.3e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 ThiS family HIG_1_N PF04588.13 KII91752.1 - 2.3e-09 37.4 0.9 3.9e-09 36.6 0.9 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region 2-Hacid_dh_C PF02826.19 KII91754.1 - 1.2e-40 138.7 0.0 1.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII91754.1 - 2.7e-16 59.4 0.0 3.3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII91754.1 - 1.2e-05 25.5 0.0 2.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Complex1_LYR PF05347.15 KII91755.1 - 9.1e-13 48.1 0.1 1.2e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UxaC PF02614.14 KII91755.1 - 0.036 12.9 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Complex1_LYR_2 PF13233.6 KII91755.1 - 0.056 14.2 0.1 0.063 14.0 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.14 KII91755.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 ETC complex I subunit conserved region DHHA2 PF02833.14 KII91756.1 - 9.7e-25 87.4 0.1 1.6e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KII91756.1 - 1.8e-09 37.7 0.2 8.3e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 DHH family FMN_dh PF01070.18 KII91757.1 - 1.7e-103 346.3 0.0 2.6e-103 345.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KII91757.1 - 0.00019 20.5 0.9 0.00029 19.9 0.9 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KII91757.1 - 0.00032 20.2 1.2 0.00046 19.7 1.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KII91757.1 - 0.00059 19.1 0.2 0.00089 18.5 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KII91757.1 - 0.00096 18.4 0.2 0.0041 16.4 0.1 1.9 1 1 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 KII91757.1 - 0.032 13.7 0.2 0.22 10.9 0.1 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 KII91757.1 - 0.047 13.0 0.6 2.4 7.4 0.1 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Ribosomal_S30 PF04758.14 KII91758.1 - 2.1e-29 101.5 5.3 2.3e-29 101.4 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Pterin_bind PF00809.22 KII91759.1 - 8.6e-66 222.1 0.0 1.2e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KII91759.1 - 2.3e-33 115.0 0.0 5.2e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 KII91759.1 - 2.5e-32 111.7 1.1 2.9e-16 60.0 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase FR47 PF08445.10 KII91760.1 - 2e-05 24.5 0.1 5.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 KII91760.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TPR_19 PF14559.6 KII91761.1 - 4e-09 36.8 1.1 0.0013 19.2 0.0 4.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KII91761.1 - 1.1e-06 29.0 2.4 0.073 13.9 0.0 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII91761.1 - 8.9e-06 25.4 0.0 0.039 14.1 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII91761.1 - 5.6e-05 23.0 0.1 0.034 14.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII91761.1 - 0.00066 20.3 0.5 3.4 8.4 0.0 4.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KII91761.1 - 0.002 18.3 1.6 0.83 9.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII91761.1 - 0.002 18.6 0.1 1.4 9.7 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KII91761.1 - 0.0032 17.2 0.2 0.059 13.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF5601 PF18151.1 KII91761.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Methyltransf_2 PF00891.18 KII91762.1 - 7.6e-19 67.8 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII91762.1 - 6.3e-05 22.8 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII91762.1 - 0.00019 22.0 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RPA_C PF08784.11 KII91762.1 - 0.00097 19.8 0.0 0.0032 18.1 0.0 1.9 1 0 0 1 1 1 1 Replication protein A C terminal Methyltransf_23 PF13489.6 KII91762.1 - 0.028 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KII91762.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KII91762.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KII91762.1 - 0.072 13.8 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rrf2 PF02082.20 KII91762.1 - 0.087 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Fungal_trans PF04082.18 KII91766.1 - 2.6e-07 30.0 0.0 4.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91766.1 - 1.9e-05 24.7 8.8 3.4e-05 23.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.22 KII91768.1 - 2e-38 131.4 4.2 7.2e-28 97.1 1.1 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KII91768.1 - 2.9e-19 69.2 0.0 5.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII91768.1 - 0.0003 20.4 0.1 0.00074 19.1 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 KII91768.1 - 0.0011 18.4 0.1 0.94 8.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII91768.1 - 0.0014 18.2 0.0 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KII91768.1 - 0.0057 16.7 0.2 0.32 11.0 0.0 2.7 3 0 0 3 3 3 1 Dynamin family cobW PF02492.19 KII91768.1 - 0.015 14.9 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KII91768.1 - 0.018 15.6 0.1 0.059 13.9 0.1 1.8 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 KII91768.1 - 0.092 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 KII91768.1 - 1.3 7.9 4.6 0.75 8.7 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TetR_C_21 PF17926.1 KII91769.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Gti1_Pac2 PF09729.9 KII91770.1 - 4.1e-40 137.8 0.0 3.3e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Gti1/Pac2 family adh_short PF00106.25 KII91772.1 - 1.3e-18 67.1 0.2 1e-16 61.0 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91772.1 - 5e-12 45.9 0.1 2.6e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91772.1 - 8.1e-05 22.6 0.3 0.00015 21.7 0.3 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII91772.1 - 0.045 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII91772.1 - 0.067 13.3 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-MYND PF01753.18 KII91773.1 - 3.2e-10 39.9 16.5 4.8e-10 39.4 16.5 1.3 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 KII91773.1 - 0.078 10.8 4.3 0.094 10.6 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C6H2 PF15801.5 KII91773.1 - 0.67 10.3 10.2 1.1 9.6 10.2 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CLN3 PF02487.17 KII91774.1 - 1.3e-126 422.9 5.3 1.6e-126 422.6 5.3 1.1 1 0 0 1 1 1 1 CLN3 protein DEAD PF00270.29 KII91775.1 - 3.2e-47 160.5 0.0 5.7e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII91775.1 - 3e-24 85.5 0.0 2.1e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KII91775.1 - 1.4e-18 66.9 0.0 2.9e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KII91775.1 - 1.2e-05 25.4 0.0 4.1e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3246 PF11596.8 KII91775.1 - 0.14 11.6 4.7 0.26 10.7 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TLP-20 PF06088.11 KII91775.1 - 1 9.2 9.9 0.067 13.1 2.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RXT2_N PF08595.11 KII91775.1 - 1.4 8.9 9.8 0.29 11.2 2.4 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal F-box-like PF12937.7 KII91776.1 - 3.2e-06 26.9 2.1 1.8e-05 24.5 2.1 2.4 1 0 0 1 1 1 1 F-box-like Syndecan PF01034.20 KII91777.1 - 0.29 11.1 0.3 0.46 10.4 0.3 1.2 1 0 0 1 1 1 0 Syndecan domain BAH PF01426.18 KII91778.1 - 4.5e-09 36.2 0.4 7.4e-09 35.5 0.4 1.3 1 0 0 1 1 1 1 BAH domain DUF1610 PF07754.11 KII91778.1 - 0.069 13.1 0.7 0.069 13.1 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Ifi-6-16 PF06140.13 KII91778.1 - 0.13 12.1 0.9 0.2 11.6 0.9 1.2 1 0 0 1 1 1 0 Interferon-induced 6-16 family AT_hook PF02178.19 KII91778.1 - 0.24 11.4 5.0 0.78 9.8 5.0 2.0 1 0 0 1 1 1 0 AT hook motif TB2_DP1_HVA22 PF03134.19 KII91779.1 - 1.4e-26 92.2 4.9 2.6e-26 91.3 4.9 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Velvet PF11754.8 KII91780.1 - 7.5e-39 134.2 0.0 1.1e-38 133.7 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Fungal_trans PF04082.18 KII91782.1 - 5e-17 61.8 0.0 9.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulf_transp PF04143.14 KII91783.1 - 0.022 14.3 0.2 0.027 14.0 0.2 1.1 1 0 0 1 1 1 0 Sulphur transport MARVEL PF01284.23 KII91783.1 - 0.055 13.5 0.2 0.088 12.8 0.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF4519 PF15012.6 KII91783.1 - 0.1 12.8 0.6 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FeoB_associated PF12669.7 KII91783.1 - 0.12 12.8 2.4 8 7.0 0.1 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2768 PF10966.8 KII91783.1 - 0.99 9.9 4.7 1.3 9.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) BTB PF00651.31 KII91784.1 - 0.00069 19.8 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DNA_ligase_ZBD PF03119.16 KII91784.1 - 0.12 12.4 0.5 11 6.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Lyase_catalyt PF09093.11 KII91784.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic Glucan_synthase PF02364.15 KII91785.1 - 0 1332.6 0.0 0 1332.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KII91785.1 - 7.5e-43 146.0 0.2 2.6e-42 144.2 0.2 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Thaumatin PF00314.17 KII91787.1 - 9.8e-72 241.1 10.0 1.1e-71 240.9 10.0 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 KII91787.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat F-box-like PF12937.7 KII91788.1 - 2.8e-09 36.7 0.5 1.5e-08 34.4 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII91788.1 - 0.00011 21.9 0.3 0.00098 18.9 0.0 2.7 2 0 0 2 2 2 1 F-box domain Smg4_UPF3 PF03467.15 KII91789.1 - 2e-31 109.4 0.2 2e-31 109.3 0.2 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family JLPA PF16668.5 KII91789.1 - 0.08 12.0 0.0 0.089 11.8 0.0 1.0 1 0 0 1 1 1 0 Adhesin from Campylobacter HLH PF00010.26 KII91790.1 - 1.3e-10 41.1 0.1 2.6e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GPI-anchored PF10342.9 KII91792.1 - 0.042 14.6 0.0 0.05 14.4 0.0 1.1 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MoCF_biosynth PF00994.24 KII91793.1 - 2.4e-32 111.6 0.0 4.6e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Peptidase_S24 PF00717.23 KII91794.1 - 9e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Glyco_hydro_30 PF02055.16 KII91795.1 - 3.1e-25 88.9 0.6 5e-25 88.2 0.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KII91795.1 - 6.2e-13 48.6 0.0 9.4e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 RE_MjaI PF09568.10 KII91796.1 - 0.13 12.1 0.1 7.6 6.3 0.1 2.8 3 0 0 3 3 3 0 MjaI restriction endonuclease SAP PF02037.27 KII91798.1 - 1.6e-05 24.6 0.3 3.2e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 KII91798.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein PTPRCAP PF15713.5 KII91798.1 - 3.2 8.0 10.1 4.8 7.5 1.4 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated F-box-like PF12937.7 KII91799.1 - 0.013 15.3 0.2 0.043 13.7 0.2 2.0 1 0 0 1 1 1 0 F-box-like Gti1_Pac2 PF09729.9 KII91801.1 - 6.5e-42 143.7 0.0 8.3e-35 120.5 0.0 2.4 2 0 0 2 2 2 2 Gti1/Pac2 family CMD PF02627.20 KII91802.1 - 0.015 15.3 0.2 0.035 14.1 0.2 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Arm_vescicular PF18770.1 KII91802.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor CUE PF02845.16 KII91802.1 - 0.13 12.0 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 CUE domain adh_short PF00106.25 KII91803.1 - 2.8e-17 62.8 0.4 1.3e-15 57.4 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91803.1 - 2.8e-11 43.4 0.1 1.4e-10 41.2 0.2 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91803.1 - 5.5e-05 23.2 0.2 9.2e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII91803.1 - 0.038 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII91803.1 - 0.052 13.6 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-MYND PF01753.18 KII91804.1 - 3.1e-11 43.1 17.3 5.2e-11 42.4 17.3 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII91804.1 - 0.078 13.3 10.6 0.14 12.5 10.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 KII91804.1 - 0.5 8.2 5.1 0.62 7.9 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GIY-YIG PF01541.24 KII91805.1 - 1.5e-10 41.2 0.0 2.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING-like PF08746.11 KII91805.1 - 1.5 9.2 3.7 1.6 9.1 0.3 2.4 2 1 0 2 2 2 0 RING-like domain DUF1752 PF08550.10 KII91806.1 - 1.9e-08 34.0 10.2 3.4e-08 33.2 10.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) cobW PF02492.19 KII91807.1 - 2.7e-42 144.4 0.0 3.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KII91807.1 - 5.3e-06 26.3 0.0 2.2e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MMR_HSR1 PF01926.23 KII91807.1 - 0.00087 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII91807.1 - 0.0038 16.8 0.4 0.13 11.8 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KII91807.1 - 0.047 14.1 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KII91807.1 - 0.084 12.8 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KII91807.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KII91809.1 - 4.6e-10 39.4 15.6 3.6e-05 24.0 5.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII91809.1 - 7.7e-08 32.5 12.0 0.0015 19.2 3.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII91809.1 - 2.9e-07 30.6 11.4 1.9e-05 24.8 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KII91809.1 - 0.0042 17.3 3.0 0.05 13.9 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII91809.1 - 0.0068 16.8 0.7 0.0068 16.8 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KII91809.1 - 0.018 14.9 10.1 0.25 11.3 2.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-DNA_Pol PF08996.10 KII91809.1 - 0.032 14.0 0.3 0.042 13.6 0.3 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn_ribbon_SprT PF17283.2 KII91809.1 - 0.039 13.9 7.7 0.14 12.1 2.2 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 KII91809.1 - 0.053 13.3 4.2 1.7 8.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type MCM_OB PF17207.3 KII91809.1 - 0.072 12.9 0.4 0.095 12.6 0.4 1.2 1 0 0 1 1 1 0 MCM OB domain zf-Di19 PF05605.12 KII91809.1 - 0.14 12.5 6.0 0.37 11.1 6.0 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KII91809.1 - 0.16 11.6 0.9 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 KII91809.1 - 0.2 11.8 0.4 0.47 10.6 0.1 1.6 1 1 0 2 2 2 0 Aberrant zinc-finger CpXC PF14353.6 KII91809.1 - 0.28 11.2 1.4 8.1 6.5 1.4 2.1 1 1 0 1 1 1 0 CpXC protein FOXP-CC PF16159.5 KII91809.1 - 0.28 11.8 1.8 1.9 9.2 0.1 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KII91809.1 - 0.77 9.8 6.9 1.9 8.6 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KII91809.1 - 0.81 10.1 4.5 1.2 9.5 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Toxin_7 PF05980.12 KII91810.1 - 0.0015 18.8 3.8 0.0034 17.6 3.8 1.6 1 1 0 1 1 1 1 Toxin 7 Toxin_12 PF07740.12 KII91810.1 - 0.014 16.1 1.7 0.039 14.6 1.7 1.9 1 1 0 1 1 1 0 Ion channel inhibitory toxin Tryp_inh PF17983.1 KII91810.1 - 0.13 12.4 6.8 0.22 11.6 6.8 1.4 1 0 0 1 1 1 0 Trypsin inhibitors 1,2 and 3 DUF3648 PF12364.8 KII91810.1 - 0.48 10.6 3.7 0.58 10.4 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3648) tRNA-synt_2b PF00587.25 KII91811.1 - 1.2e-34 119.8 0.0 2.9e-34 118.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KII91811.1 - 1.9e-19 69.6 0.1 3.7e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KII91811.1 - 3.1e-15 56.0 0.0 6.6e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KII91811.1 - 1e-12 47.9 0.0 2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.6 KII91812.1 - 2.4e-28 98.4 2.4 2.4e-28 98.4 2.4 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KII91812.1 - 7.8e-22 76.9 0.0 1.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KII91812.1 - 2.7e-14 52.4 5.1 2.7e-14 52.4 5.1 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KII91812.1 - 0.045 13.9 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif DUF3106 PF11304.8 KII91812.1 - 0.11 13.0 0.6 0.88 10.1 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) F-box-like PF12937.7 KII91813.1 - 8.8e-10 38.3 1.4 1.6e-09 37.5 1.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII91813.1 - 0.011 15.6 1.0 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 F-box domain RasGAP_C PF03836.15 KII91813.1 - 0.021 15.0 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 RasGAP C-terminus GLTP PF08718.11 KII91813.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) BTB PF00651.31 KII91815.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII91816.1 - 1.5e-07 31.6 0.0 3.5e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Toxin_7 PF05980.12 KII91817.1 - 0.004 17.4 3.5 0.0068 16.6 3.5 1.4 1 0 0 1 1 1 1 Toxin 7 Toxin_12 PF07740.12 KII91817.1 - 0.15 12.8 2.4 0.23 12.2 2.4 1.4 1 0 0 1 1 1 0 Ion channel inhibitory toxin Tachystatin_A PF11406.8 KII91817.1 - 0.18 11.9 4.5 0.31 11.1 4.5 1.4 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A F-box-like PF12937.7 KII91818.1 - 6.4e-08 32.4 2.7 1.8e-07 31.0 2.7 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII91818.1 - 0.25 11.3 3.1 3.2 7.7 0.3 2.5 2 0 0 2 2 2 0 F-box domain HSP20 PF00011.21 KII91819.1 - 3.3e-15 56.1 0.0 3.7e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII91819.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA COesterase PF00135.28 KII91820.1 - 1.3e-86 291.6 0.4 1.7e-85 287.9 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII91820.1 - 2e-11 44.2 0.4 1.8e-10 41.0 0.3 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KII91820.1 - 0.011 15.4 0.4 0.034 13.8 0.4 1.6 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 KII91820.1 - 0.024 14.1 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DIM PF08194.12 KII91820.1 - 0.062 13.5 1.7 13 6.1 0.1 2.9 3 0 0 3 3 3 0 DIM protein Peptidase_C36 PF05415.11 KII91820.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Fungal_trans PF04082.18 KII91821.1 - 1.4e-08 34.2 0.0 2.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91821.1 - 0.00012 22.2 13.1 0.00024 21.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TBCC PF07986.12 KII91822.1 - 1.8e-24 85.8 0.1 3.2e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KII91822.1 - 7.3e-11 42.5 0.2 1.7e-10 41.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain ParE_toxin PF05016.15 KII91823.1 - 1.1 9.9 6.7 0.22 12.1 0.4 3.2 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE zf-rbx1 PF12678.7 KII91825.1 - 2.7e-24 85.2 12.9 3.9e-24 84.7 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII91825.1 - 3.2e-16 59.2 9.5 4.1e-16 58.8 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KII91825.1 - 7.7e-06 26.1 15.4 0.0003 21.1 15.4 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII91825.1 - 0.0012 18.6 11.8 0.024 14.5 11.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII91825.1 - 0.0015 18.3 14.6 0.0019 18.0 9.1 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII91825.1 - 0.22 11.4 10.9 0.68 9.8 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KII91825.1 - 0.22 11.7 9.3 0.96 9.7 9.5 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 KII91825.1 - 0.26 11.4 7.1 0.86 9.7 7.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KII91825.1 - 0.53 9.9 14.3 0.17 11.5 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KII91825.1 - 1.6 8.5 17.0 87 3.0 17.0 2.4 1 1 0 1 1 1 0 RING-like zinc finger CRC_subunit PF08624.10 KII91827.1 - 5.9e-43 146.5 0.0 9.2e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit MID_MedPIWI PF18296.1 KII91828.1 - 3 7.6 10.7 1.7e+02 1.8 10.7 2.2 1 1 0 1 1 1 0 MID domain of medPIWI TLP-20 PF06088.11 KII91828.1 - 5.6 6.8 11.7 0.68 9.8 3.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FYDLN_acid PF09538.10 KII91828.1 - 7.9 7.2 18.8 1.9 9.2 9.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Abhydrolase_2 PF02230.16 KII91829.1 - 1.8e-11 44.3 0.0 1.7e-09 37.8 0.0 2.2 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KII91829.1 - 0.00052 20.7 0.6 0.0007 20.3 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KII91829.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Piwi PF02171.17 KII91830.1 - 1.5e-78 264.1 0.0 2.1e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KII91830.1 - 1.3e-24 87.4 0.0 3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KII91830.1 - 7.3e-22 76.8 0.5 1.7e-21 75.6 0.5 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KII91830.1 - 2.6e-15 56.5 0.1 4.3e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KII91830.1 - 6.6e-10 39.2 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain DUF3726 PF12525.8 KII91831.1 - 0.13 12.3 0.0 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Ribonucleas_3_3 PF14622.6 KII91832.1 - 3.1e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII91832.1 - 2e-10 41.2 0.0 4.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Tetraspanin PF00335.20 KII91833.1 - 0.00028 20.7 5.1 0.00028 20.7 5.1 1.9 1 1 1 2 2 2 1 Tetraspanin family TctB PF07331.11 KII91833.1 - 0.65 10.3 7.1 0.72 10.1 3.8 2.0 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Presenilin PF01080.17 KII91833.1 - 0.94 8.2 5.1 0.22 10.2 0.2 1.9 2 0 0 2 2 2 0 Presenilin CAP_N PF01213.19 KII91833.1 - 5.5 6.4 5.2 3.6 7.0 0.3 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PIG-F PF06699.11 KII91834.1 - 2.4e-33 115.8 5.8 3.8e-33 115.2 5.8 1.3 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Hydrolase_6 PF13344.6 KII91835.1 - 8.1e-30 102.9 0.0 1.5e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII91835.1 - 5.2e-19 68.1 0.0 1.6e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KII91835.1 - 2.6e-12 47.5 0.0 4.2e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KII91835.1 - 4.2e-08 33.5 0.0 0.00092 19.3 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KII91835.1 - 0.012 15.3 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Rox3 PF08633.10 KII91835.1 - 0.054 13.8 0.1 0.077 13.3 0.1 1.2 1 0 0 1 1 1 0 Rox3 mediator complex subunit Fungal_trans PF04082.18 KII91836.1 - 1e-07 31.3 0.2 2.2e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91836.1 - 0.0004 20.4 12.8 0.00091 19.3 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Calpain_inhib PF00748.19 KII91836.1 - 0.2 12.1 0.1 0.39 11.2 0.1 1.4 1 0 0 1 1 1 0 Calpain inhibitor TAL_FSA PF00923.19 KII91837.1 - 3.6e-22 79.1 0.1 4.9e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SAM_PNT PF02198.16 KII91838.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain bZIP_2 PF07716.15 KII91839.1 - 5.7e-06 26.3 7.5 0.00079 19.5 0.3 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KII91839.1 - 6.3e-05 23.0 6.5 0.00068 19.7 0.8 2.2 2 0 0 2 2 2 2 bZIP transcription factor YabA PF06156.13 KII91839.1 - 0.0083 16.7 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Initiation control protein YabA Shugoshin_N PF07558.11 KII91839.1 - 0.028 14.3 2.9 0.084 12.8 1.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 KII91839.1 - 0.035 13.9 1.5 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KII91839.1 - 0.047 14.0 2.5 0.08 13.3 1.2 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 KII91839.1 - 0.38 11.3 4.0 2.6 8.6 0.4 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor NYD-SP28_assoc PF14775.6 KII91839.1 - 2.2 8.5 5.4 0.49 10.5 1.5 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Fic PF02661.18 KII91840.1 - 4.9e-12 46.6 0.0 1.8e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family TIMELESS PF04821.14 KII91841.1 - 9.4e-73 244.9 0.0 9.4e-73 244.9 0.0 2.3 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KII91841.1 - 4.7e-10 39.3 9.8 4.7e-10 39.3 9.8 3.6 2 1 1 3 3 3 1 Timeless protein C terminal region TSGP1 PF07771.11 KII91841.1 - 2.4 8.3 8.5 10 6.3 8.5 2.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 FAM176 PF14851.6 KII91841.1 - 8.1 6.1 11.9 10 5.8 0.2 2.8 2 0 0 2 2 2 0 FAM176 family BTB PF00651.31 KII91842.1 - 1.3e-07 31.9 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Polysacc_synt_4 PF04669.13 KII91843.1 - 1.9e-20 73.2 0.7 3.2e-18 66.0 0.7 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis CinA PF02464.17 KII91844.1 - 4.8e-28 97.7 2.0 5.8e-28 97.4 2.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein WW PF00397.26 KII91846.1 - 6.6e-10 38.9 4.1 1.7e-09 37.6 4.1 1.7 1 0 0 1 1 1 1 WW domain Usp PF00582.26 KII91847.1 - 1.9e-17 64.1 0.2 2.6e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 Universal stress protein family FR47 PF08445.10 KII91848.1 - 1.9e-10 40.6 0.1 4.1e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KII91848.1 - 1.7e-09 37.9 0.1 2.6e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII91848.1 - 1.1e-07 31.9 0.1 1.7e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII91848.1 - 7.5e-07 29.5 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII91848.1 - 0.00085 19.4 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII91848.1 - 0.0028 18.3 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII91848.1 - 0.0037 16.9 0.0 0.0099 15.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KII91848.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KII91848.1 - 0.019 15.1 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 KII91848.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase F-box-like PF12937.7 KII91849.1 - 0.019 14.9 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.6 KII91849.1 - 0.35 10.7 1.8 7.4 6.4 0.1 3.4 3 1 0 3 3 3 0 Leucine rich repeat Pro_CA PF00484.19 KII91850.1 - 2.2e-37 128.8 0.0 4e-37 127.9 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase BTB PF00651.31 KII91851.1 - 3.6e-08 33.6 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NqrM PF04400.13 KII91851.1 - 0.026 14.3 2.0 0.05 13.3 2.0 1.4 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM BTB PF00651.31 KII91852.1 - 8.6e-07 29.2 0.0 1.8e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Thaumatin PF00314.17 KII91853.1 - 5.3e-72 241.9 8.7 6.1e-72 241.7 8.7 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 KII91853.1 - 0.064 13.2 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat BTB PF00651.31 KII91854.1 - 1.4e-08 35.0 0.0 3.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII91856.1 - 8.3e-11 42.1 0.2 4.8e-10 39.7 0.1 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KII91857.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TMEM219 PF14940.6 KII91857.1 - 0.082 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 219 FHA PF00498.26 KII91858.1 - 1.7e-07 31.5 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KII91858.1 - 0.00035 20.8 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Beta-lactamase PF00144.24 KII91859.1 - 5.4e-37 127.8 0.0 1.6e-36 126.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase VbhA PF18495.1 KII91859.1 - 0.019 14.8 0.1 1.1 9.1 0.0 2.9 2 0 0 2 2 2 0 Antitoxin VbhA Beta-lactamase2 PF13354.6 KII91859.1 - 0.039 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family BTB PF00651.31 KII91861.1 - 2.8e-08 34.0 0.0 3.3e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 KII91862.1 - 6.3e-07 29.6 0.0 2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Neisseria_PilC PF05567.11 KII91862.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Isy1 PF06246.12 KII91863.1 - 1.3e-93 313.3 1.8 1.6e-93 313.0 1.8 1.1 1 0 0 1 1 1 1 Isy1-like splicing family MbeD_MobD PF04899.12 KII91863.1 - 0.027 14.6 0.2 0.088 12.9 0.1 1.8 2 0 0 2 2 2 0 MbeD/MobD like Sugar_tr PF00083.24 KII91864.1 - 3.7e-107 359.0 22.9 4.4e-107 358.7 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII91864.1 - 7.6e-26 90.9 34.5 2.6e-25 89.1 33.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII91864.1 - 9e-06 24.4 3.8 9e-06 24.4 3.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KII91864.1 - 0.0015 17.0 1.7 0.0015 17.0 1.7 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector MASE3 PF17159.4 KII91864.1 - 0.46 10.1 5.3 1.3 8.6 5.3 1.8 1 0 0 1 1 1 0 Membrane-associated sensor domain N2227 PF07942.12 KII91865.1 - 7.2e-91 304.1 0.0 8.9e-91 303.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KII91865.1 - 0.0075 17.0 0.0 0.034 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII91865.1 - 0.0077 16.1 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII91865.1 - 0.017 15.7 0.0 0.36 11.5 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain AF-4 PF05110.13 KII91865.1 - 0.056 11.6 3.0 0.063 11.4 3.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SelP_N PF04592.14 KII91865.1 - 2.5 7.4 11.0 3.9 6.8 11.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region adh_short PF00106.25 KII91866.1 - 4.6e-31 107.8 0.0 3.1e-26 92.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII91866.1 - 4.4e-17 62.4 0.0 1e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91866.1 - 4.7e-07 29.9 0.1 8.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII91866.1 - 0.018 14.5 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII91866.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Molybdopterin PF00384.22 KII91867.1 - 3.8e-67 227.1 0.0 2.7e-66 224.3 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KII91867.1 - 5.5e-20 71.2 0.3 1.4e-19 69.9 0.3 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KII91867.1 - 2.5e-17 62.1 0.2 2.5e-17 62.1 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KII91867.1 - 3.7e-16 59.5 0.1 1e-15 58.1 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KII91867.1 - 8.4e-09 35.3 0.5 8.4e-09 35.3 0.5 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KII91867.1 - 0.0085 15.8 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain JAB PF01398.21 KII91869.1 - 1.1e-15 57.6 1.9 2.1e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KII91869.1 - 7e-12 45.5 0.1 1.5e-11 44.4 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KII91869.1 - 2e-05 24.4 0.0 2e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF357 PF04010.13 KII91869.1 - 0.0092 16.0 0.3 0.025 14.6 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) RNase_PH PF01138.21 KII91870.1 - 8.3e-22 78.1 0.0 7.2e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Glyco_transf_90 PF05686.12 KII91871.1 - 1.1e-13 50.8 1.7 2.6e-11 43.1 0.6 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 adh_short_C2 PF13561.6 KII91872.1 - 1.6e-55 188.2 0.3 2.5e-55 187.6 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII91872.1 - 1.5e-51 174.6 0.2 1.9e-51 174.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII91872.1 - 1.1e-07 31.9 0.6 1.8e-07 31.3 0.6 1.3 1 1 0 1 1 1 1 KR domain Transketolase_C PF02780.20 KII91872.1 - 0.023 14.6 0.2 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 Transketolase, C-terminal domain Epimerase PF01370.21 KII91872.1 - 0.11 11.9 0.2 0.26 10.7 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_43 PF04616.14 KII91874.1 - 4.2e-71 239.6 0.8 6.3e-71 239.0 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KII91874.1 - 2.1e-23 83.1 0.0 3e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF4470 PF14737.6 KII91875.1 - 1.4e-06 28.4 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 KII91875.1 - 6.7e-06 25.8 5.1 0.016 15.3 2.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII91875.1 - 2.8e-05 23.7 5.7 0.00019 21.1 3.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII91875.1 - 0.00089 19.9 1.5 0.18 12.7 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Poty_PP PF08440.10 KII91875.1 - 0.0011 18.1 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Potyviridae polyprotein TPR_16 PF13432.6 KII91875.1 - 0.0013 19.3 3.0 0.004 17.8 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII91875.1 - 0.038 14.3 0.7 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KII91875.1 - 0.082 12.6 4.9 0.089 12.5 3.2 2.0 1 1 1 2 2 2 0 TPR repeat TPR_8 PF13181.6 KII91875.1 - 0.17 12.1 4.8 0.17 12.2 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KII91876.1 - 6.3e-60 202.6 1.0 7.9e-60 202.3 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII91876.1 - 1.1e-49 168.5 2.5 1.5e-49 168.1 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII91876.1 - 8.4e-18 64.9 0.5 1.8e-17 63.8 0.4 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KII91876.1 - 0.0036 16.8 0.4 0.0055 16.2 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII91876.1 - 0.013 15.0 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KII91876.1 - 0.026 14.4 0.4 0.31 10.9 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.13 KII91876.1 - 0.069 13.1 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Adenylsucc_synt PF00709.21 KII91876.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Polysacc_synt_2 PF02719.15 KII91876.1 - 0.077 12.1 0.2 0.22 10.6 0.2 1.7 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein Cation_efflux PF01545.21 KII91877.1 - 2.9e-07 30.4 0.6 7.3e-07 29.1 0.4 1.7 1 1 0 1 1 1 1 Cation efflux family SURF6 PF04935.12 KII91878.1 - 1.1e-44 152.6 50.5 1.1e-44 152.6 50.5 2.9 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KII91878.1 - 2.2e-22 79.4 7.9 2.2e-22 79.4 7.9 6.1 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 PTPA PF03095.15 KII91879.1 - 2.3e-125 418.1 0.0 2.6e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Chitin_synth_2 PF03142.15 KII91880.1 - 1.1e-238 793.1 0.6 1.5e-238 792.7 0.6 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KII91880.1 - 4.3e-141 471.4 0.0 2.8e-140 468.7 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KII91880.1 - 2.2e-18 65.9 0.0 7.1e-18 64.3 0.1 1.9 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KII91880.1 - 5.8e-12 45.6 0.0 5.3e-07 29.7 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KII91880.1 - 5.4e-09 36.2 6.3 1.7e-08 34.7 4.6 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KII91880.1 - 1.1e-08 35.2 0.3 2e-07 31.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KII91880.1 - 0.051 13.4 0.0 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 AAA_29 PF13555.6 KII91880.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 KII91881.1 - 3.2e-84 282.8 19.9 1.3e-43 149.6 3.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII91881.1 - 5.3e-61 205.1 0.1 6.2e-30 104.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KII91881.1 - 2.3e-14 53.4 3.4 1.4e-05 24.6 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII91881.1 - 7.2e-11 42.8 1.1 0.00021 21.7 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KII91881.1 - 6.6e-10 39.4 0.5 0.0039 17.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KII91881.1 - 2e-08 34.4 0.0 0.68 9.7 0.0 4.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KII91881.1 - 3.6e-08 33.3 0.1 0.69 9.6 0.0 4.4 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_29 PF13555.6 KII91881.1 - 1.1e-07 31.5 0.2 0.021 14.6 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KII91881.1 - 3.1e-07 30.3 0.6 0.038 13.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KII91881.1 - 1.9e-06 27.3 0.1 0.012 14.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ABC_ATPase PF09818.9 KII91881.1 - 2.8e-06 26.4 0.0 0.00093 18.1 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KII91881.1 - 1.6e-05 24.6 0.5 1.1 8.7 0.0 4.9 6 0 0 6 6 5 2 AAA domain AAA_15 PF13175.6 KII91881.1 - 1.6e-05 24.8 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KII91881.1 - 2.2e-05 24.4 0.0 0.33 10.9 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_5 PF07728.14 KII91881.1 - 2.6e-05 24.3 0.0 0.2 11.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KII91881.1 - 2.8e-05 24.7 0.0 0.24 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KII91881.1 - 0.00011 22.4 0.1 0.16 12.0 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_33 PF13671.6 KII91881.1 - 0.00024 21.3 0.2 1.1 9.4 0.3 2.8 2 1 0 2 2 2 2 AAA domain APS_kinase PF01583.20 KII91881.1 - 0.00047 20.1 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF2075 PF09848.9 KII91881.1 - 0.00072 18.9 0.0 0.14 11.4 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.6 KII91881.1 - 0.0013 18.9 0.2 1.7 8.9 0.2 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KII91881.1 - 0.0015 19.0 0.1 0.99 9.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII91881.1 - 0.0031 17.1 0.0 0.87 9.1 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region G-alpha PF00503.20 KII91881.1 - 0.0041 16.3 0.0 0.83 8.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.6 KII91881.1 - 0.0045 17.2 4.3 2.4 8.4 0.1 4.3 4 1 1 5 5 4 1 AAA domain RNA_helicase PF00910.22 KII91881.1 - 0.0059 17.0 0.0 3.5 8.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 KII91881.1 - 0.006 16.0 0.1 7.1 6.0 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KII91881.1 - 0.0065 16.2 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 KII91881.1 - 0.0091 15.4 0.0 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KII91881.1 - 0.01 15.6 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KII91881.1 - 0.01 16.2 0.6 4.2 7.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KII91881.1 - 0.011 14.9 0.1 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KII91881.1 - 0.012 15.4 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KII91881.1 - 0.014 15.4 0.0 8 6.4 0.0 2.9 3 0 0 3 3 2 0 NACHT domain CPT PF07931.12 KII91881.1 - 0.018 14.9 0.2 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 KII91881.1 - 0.025 13.7 0.0 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase PF06745.13 KII91881.1 - 0.034 13.5 1.0 5.8 6.2 0.0 2.9 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.6 KII91881.1 - 0.035 14.2 0.0 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain CbiA PF01656.23 KII91881.1 - 0.037 14.1 0.0 10 6.2 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ploopntkinase3 PF18751.1 KII91881.1 - 0.051 13.5 0.0 9.2 6.1 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 KII91881.1 - 0.051 12.6 0.0 3.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KII91881.1 - 0.064 13.3 0.0 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KII91881.1 - 0.077 12.8 0.1 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KII91881.1 - 0.11 12.6 0.0 11 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain CoaE PF01121.20 KII91881.1 - 0.12 12.1 0.2 20 4.8 0.0 2.5 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_19 PF13245.6 KII91881.1 - 0.21 11.9 1.7 13 6.1 0.3 3.3 2 2 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 KII91883.1 - 4.9e-29 100.7 10.1 6.2e-29 100.4 10.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 KII91883.1 - 0.38 11.4 4.4 0.54 10.9 4.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Metallophos PF00149.28 KII91884.1 - 1.8e-12 48.2 1.5 3.4e-12 47.3 1.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII91884.1 - 1.1e-05 25.7 0.0 0.00011 22.5 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Fungal_trans PF04082.18 KII91885.1 - 4.7e-07 29.1 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91885.1 - 0.00054 20.0 3.1 0.00094 19.3 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 KII91886.1 - 8.1e-07 29.1 6.5 1.3e-06 28.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KII91887.1 - 2.4e-36 125.4 32.7 2.4e-36 125.4 32.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII91887.1 - 1.5e-15 57.1 8.6 1.5e-15 57.1 8.6 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KII91887.1 - 1.8e-07 30.0 1.1 2.7e-07 29.4 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KII91887.1 - 0.56 8.4 9.5 0.28 9.4 3.7 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 KII91889.1 - 2.8e-18 65.9 8.0 0.01 16.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 KII91889.1 - 1.4e-15 57.5 0.0 2.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KII91889.1 - 0.0023 16.7 0.3 0.16 10.6 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KII91889.1 - 0.015 15.6 0.1 9 6.7 0.0 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KII91889.1 - 0.038 14.5 0.4 9.1 6.9 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain PI-PLC-X PF00388.19 KII91890.1 - 5.2e-53 178.5 0.0 9.7e-53 177.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KII91890.1 - 3.8e-43 146.5 0.1 8.4e-43 145.4 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KII91890.1 - 3.1e-06 27.4 0.0 0.0039 17.5 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 KII91890.1 - 1.3e-05 25.5 2.6 3.7e-05 24.1 2.6 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.6 KII91890.1 - 7.5e-05 22.5 0.7 0.00021 21.1 0.7 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KII91890.1 - 9.8e-05 21.6 0.9 0.2 11.3 0.2 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KII91890.1 - 0.011 15.6 1.8 2.6 8.2 0.5 3.1 2 0 0 2 2 2 0 EF-hand domain DUF1570 PF07607.11 KII91890.1 - 0.011 16.1 1.1 0.19 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1570) PH_12 PF16457.5 KII91890.1 - 0.013 16.0 0.4 0.059 13.9 0.1 2.3 2 1 0 2 2 1 0 Pleckstrin homology domain EF-hand_like PF09279.11 KII91890.1 - 0.039 14.4 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Chlam_OMP6 PF03504.13 KII91890.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 F-box-like PF12937.7 KII91891.1 - 1.9e-05 24.5 0.3 9.1e-05 22.3 0.3 2.3 1 0 0 1 1 1 1 F-box-like Beta-lactamase PF00144.24 KII91892.1 - 2.8e-43 148.4 1.1 1e-42 146.6 1.1 1.9 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KII91892.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KII91892.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase enzyme family DUF5570 PF17731.1 KII91893.1 - 0.15 12.2 0.2 0.15 12.2 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5570) MMR_HSR1 PF01926.23 KII91897.1 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KII91897.1 - 0.0054 16.2 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 KII91897.1 - 0.006 16.3 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KII91897.1 - 0.013 15.3 0.1 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KII91897.1 - 0.023 14.9 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KII91897.1 - 0.042 14.1 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KII91897.1 - 0.044 12.9 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 KII91897.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KII91897.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 KII91897.1 - 0.081 12.5 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2559 PF10832.8 KII91897.1 - 0.099 12.7 0.1 0.72 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Birna_VP5 PF03042.14 KII91903.1 - 0.017 15.1 0.3 0.017 15.1 0.3 1.7 1 1 1 2 2 2 0 Birnavirus VP5 protein DUF2326 PF10088.9 KII91905.1 - 0.019 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Pkinase_fungal PF17667.1 KII91906.1 - 2e-07 30.1 0.2 4.3e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF1843 PF08898.10 KII91907.1 - 0.16 12.5 0.5 0.24 11.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) PIF1 PF05970.14 KII91908.1 - 5.7e-27 94.8 0.1 5.3e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 KII91908.1 - 3.3e-16 59.6 0.1 3.6e-07 30.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KII91908.1 - 6.2e-06 26.6 0.0 5.5e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII91908.1 - 0.00015 22.2 0.2 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KII91908.1 - 0.00075 19.8 0.0 0.65 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII91908.1 - 0.0014 18.3 0.1 0.035 13.8 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain DEAD PF00270.29 KII91908.1 - 0.0021 17.9 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.6 KII91908.1 - 0.004 17.0 0.0 0.15 11.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KII91908.1 - 0.0047 16.3 0.1 0.0074 15.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KII91908.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein RsgA_GTPase PF03193.16 KII91908.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 KII91908.1 - 0.013 15.5 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 KII91908.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KII91908.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KII91908.1 - 0.031 14.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KII91908.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KII91908.1 - 0.091 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KII91908.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KII91908.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 KII91908.1 - 0.17 11.0 0.0 0.57 9.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KII91908.1 - 0.19 11.4 0.0 11 5.7 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KII91908.1 - 0.3 11.0 0.0 1.8 8.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 KII91909.1 - 0.004 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase CD225 PF04505.12 KII91909.1 - 0.019 15.1 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein SH3_13 PF18335.1 KII91909.1 - 0.12 12.2 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain SR-25 PF10500.9 KII91909.1 - 0.36 10.4 10.6 0.16 11.6 6.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rot1 PF10681.9 KII91910.1 - 3.1e-51 173.9 0.1 3.7e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Pkinase_fungal PF17667.1 KII91911.1 - 1.3e-21 76.8 0.0 1.3e-21 76.8 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase Rrn6 PF10214.9 KII91913.1 - 4.2 5.8 7.0 4.9 5.5 7.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Integrase_H2C2 PF17921.1 KII91914.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain gag-asp_proteas PF13975.6 KII91915.1 - 0.077 13.6 0.0 0.3 11.7 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 KII91915.1 - 0.73 10.0 2.7 1.5 9.0 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle RMMBL PF07521.12 KII91916.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain RVP_2 PF08284.11 KII91923.1 - 2.9e-08 33.6 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KII91923.1 - 3.9e-05 24.2 0.0 7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KII91923.1 - 0.00034 21.1 0.0 0.00062 20.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KII91923.1 - 0.0052 16.6 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease BAALC_N PF06989.12 KII91923.1 - 0.13 12.5 0.3 50 4.3 0.0 3.0 3 0 0 3 3 3 0 BAALC N-terminus ECM11 PF15463.6 KII91928.1 - 0.0025 18.4 0.1 0.0025 18.4 0.1 1.9 2 0 0 2 2 2 1 Extracellular mutant protein 11 zf-MYND PF01753.18 KII91929.1 - 0.00036 20.6 9.8 0.00036 20.6 9.8 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KII91929.1 - 0.13 12.6 6.3 0.29 11.5 6.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Zn_clus PF00172.18 KII91932.1 - 2e-05 24.6 9.0 3.6e-05 23.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KII91932.1 - 0.092 12.7 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 PAS fold Glyco_hydro_16 PF00722.21 KII91941.1 - 0.0014 18.1 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PHD_3 PF13922.6 KII91941.1 - 0.095 13.1 0.4 0.27 11.6 0.4 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Glyco_hydro_65m PF03632.15 KII91942.1 - 2.1e-40 138.8 0.9 3.1e-35 121.8 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KII91942.1 - 4.4e-33 114.8 0.0 9.6e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 KII91942.1 - 4.8e-10 39.6 0.7 4.8e-10 39.6 0.7 2.6 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hydro_65C PF03633.15 KII91942.1 - 1.2e-06 28.3 0.0 4.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain BTB PF00651.31 KII91943.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Anoctamin PF04547.12 KII91947.1 - 0.033 13.0 1.0 3.8 6.3 0.1 2.4 2 1 0 2 2 2 0 Calcium-activated chloride channel DUF5591 PF17884.1 KII91949.1 - 0.13 12.1 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5591) zf-RING-like PF08746.11 KII91953.1 - 0.0033 17.7 0.1 0.0053 17.0 0.1 1.3 1 0 0 1 1 1 1 RING-like domain BTB PF00651.31 KII91953.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain Pkinase_fungal PF17667.1 KII91955.1 - 9e-64 215.7 0.2 1.2e-63 215.4 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII91955.1 - 3.8e-05 23.2 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91955.1 - 8.5e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Carn_acyltransf PF00755.20 KII91956.1 - 2.4e-209 696.8 0.0 2.7e-209 696.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase_fungal PF17667.1 KII91958.1 - 4.8e-58 196.9 0.0 6.9e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII91958.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII91958.1 - 0.021 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AMP-binding PF00501.28 KII91960.1 - 1.8e-94 316.8 0.1 1.8e-94 316.8 0.1 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII91960.1 - 6e-25 88.0 0.8 5e-24 85.1 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KII91960.1 - 2.8e-13 49.6 1.2 6.3e-13 48.4 0.4 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HNH_2 PF13391.6 KII91961.1 - 5.1e-07 29.7 0.5 9.8e-07 28.8 0.5 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_1 PF00232.18 KII91962.1 - 5.8e-154 512.8 0.1 7e-154 512.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 FMN_red PF03358.15 KII91962.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Peroxin-3 PF04882.12 KII91963.1 - 4.8e-136 454.5 0.1 6e-136 454.2 0.1 1.1 1 0 0 1 1 1 1 Peroxin-3 Baculo_Y142 PF04913.12 KII91963.1 - 0.16 10.6 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Baculovirus Y142 protein RhoGAP PF00620.27 KII91965.1 - 1e-06 28.6 0.0 2.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain FTZ PF03867.14 KII91966.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 1 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region SlyX PF04102.12 KII91966.1 - 0.11 13.2 0.3 0.47 11.1 0.0 2.1 2 0 0 2 2 2 0 SlyX DEAD PF00270.29 KII91969.1 - 2.7e-11 43.5 0.0 8.3e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KII91969.1 - 0.0015 18.5 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII91969.1 - 0.014 15.8 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII91969.1 - 0.055 14.2 0.3 0.13 13.0 0.3 1.6 1 0 0 1 1 1 0 RecQ zinc-binding Oxidored_FMN PF00724.20 KII91970.1 - 1.4e-78 264.6 0.0 8.9e-78 261.9 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII91971.1 - 1.5e-95 320.4 0.0 1.7e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N PF00107.26 KII91972.1 - 1.1e-15 57.7 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII91972.1 - 1.1e-06 29.8 0.0 2.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII91972.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 KII91972.1 - 0.029 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 KII91972.1 - 0.04 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_FMN PF00724.20 KII91973.1 - 1.2e-87 294.4 0.0 1.4e-87 294.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KII91975.1 - 5.5e-89 298.8 0.0 6.3e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.23 KII91976.1 - 3.4e-07 30.4 0.5 6.3e-05 23.0 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KII91976.1 - 6e-06 25.8 0.0 8.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KII91976.1 - 0.00016 21.3 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KII91976.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ferritin_2 PF13668.6 KII91977.1 - 7.9e-46 155.6 2.0 1.5e-45 154.7 2.0 1.5 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KII91977.1 - 0.0027 18.4 1.9 0.016 15.9 1.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4439) Rubrerythrin PF02915.17 KII91977.1 - 0.082 13.3 0.2 0.26 11.7 0.1 1.8 1 1 0 1 1 1 0 Rubrerythrin F-box-like PF12937.7 KII91979.1 - 2.3e-07 30.6 2.0 2.3e-07 30.6 2.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII91979.1 - 0.023 15.1 0.3 0.62 10.6 0.0 3.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) APG5 PF04106.12 KII91980.1 - 6.9e-63 212.3 0.0 9.1e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Fungal_trans PF04082.18 KII91982.1 - 9.3e-07 28.1 1.4 1.6e-06 27.4 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII91982.1 - 0.00012 22.2 10.0 0.0002 21.4 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.16 KII91983.1 - 1.3e-22 80.6 15.5 1.6e-22 80.2 15.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KII91983.1 - 6.8e-07 29.5 39.7 0.00025 21.2 16.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KII91983.1 - 0.007 15.6 13.8 0.022 14.0 13.8 1.7 1 1 0 1 1 1 1 UAA transporter family Peptidase_C12 PF01088.21 KII91986.1 - 1.1e-53 182.1 0.0 1.6e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KII91986.1 - 1.4e-14 53.7 0.2 3.5e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases T2SSF PF00482.23 KII91986.1 - 0.088 12.8 1.3 6.4 6.7 0.0 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F HTH_57 PF18679.1 KII91986.1 - 0.097 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 ThcOx helix turn helix domain Med31 PF05669.12 KII91987.1 - 1.2e-35 121.4 6.2 1.4e-35 121.1 6.2 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.11 KII91987.1 - 0.15 12.0 2.8 3.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Nodule-specific GRP repeat Aldo_ket_red PF00248.21 KII91988.1 - 3.3e-45 154.5 0.1 5.1e-43 147.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII91989.1 - 3e-42 144.8 0.0 3.7e-33 115.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family F-box-like PF12937.7 KII91990.1 - 2e-09 37.2 1.3 3.1e-09 36.6 1.0 1.5 1 1 0 1 1 1 1 F-box-like DHR10 PF18595.1 KII91990.1 - 0.01 15.9 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain BST2 PF16716.5 KII91990.1 - 0.044 14.4 0.4 0.064 13.8 0.4 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 KII91990.1 - 0.055 13.7 0.8 0.076 13.2 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KII91990.1 - 0.06 13.6 0.8 0.084 13.1 0.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding RasGAP_C PF03836.15 KII91990.1 - 0.066 13.4 0.2 0.095 12.8 0.2 1.1 1 0 0 1 1 1 0 RasGAP C-terminus FlaC_arch PF05377.11 KII91990.1 - 0.072 13.5 0.8 0.11 12.9 0.8 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 KII91990.1 - 0.14 12.4 0.3 0.19 12.0 0.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Aldo_ket_red PF00248.21 KII91992.1 - 1.1e-45 156.0 0.0 3.2e-43 148.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII91993.1 - 2.1e-41 142.1 0.0 2.1e-30 105.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family adh_short PF00106.25 KII91994.1 - 2.6e-25 89.0 0.7 3.2e-25 88.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII91994.1 - 6e-22 78.3 0.9 7.6e-22 78.0 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII91994.1 - 1.1e-07 31.9 0.2 1.4e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII91994.1 - 1.3e-05 25.2 0.9 1.6e-05 24.8 0.9 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII91994.1 - 7.8e-05 22.2 0.1 0.00013 21.5 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KII91994.1 - 0.013 15.4 0.1 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Sugar_tr PF00083.24 KII91995.1 - 2.6e-82 277.1 21.1 3.1e-82 276.8 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII91995.1 - 1e-18 67.4 38.3 7.9e-13 48.0 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KII91995.1 - 0.74 8.0 13.6 0.074 11.3 1.4 3.0 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family zf-CCCH PF00642.24 KII91996.1 - 0.087 12.8 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.24 KII91997.1 - 1.7e-07 31.0 2.6 4e-07 29.8 2.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII91997.1 - 2.3e-06 27.2 3.0 4.6e-06 26.3 3.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KII91997.1 - 2.6e-06 27.3 5.4 5.7e-06 26.2 5.4 1.6 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KII91997.1 - 0.025 15.3 0.2 0.054 14.2 0.2 1.6 1 0 0 1 1 1 0 Torus domain DUF5017 PF16409.5 KII91997.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5017) zf-CCCH_2 PF14608.6 KII91997.1 - 0.22 12.1 2.8 0.45 11.1 2.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger REV PF00424.18 KII91997.1 - 1.1 9.3 4.2 0.84 9.7 1.0 2.2 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) HTH_21 PF13276.6 KII91999.1 - 0.00013 22.0 0.2 0.12 12.6 0.1 2.3 2 0 0 2 2 2 2 HTH-like domain HTH_32 PF13565.6 KII91999.1 - 0.00037 21.0 1.7 0.076 13.6 0.2 2.5 1 1 1 2 2 2 2 Homeodomain-like domain CSN4_RPN5_eIF3a PF18420.1 KII91999.1 - 0.091 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain DUF218 PF02698.17 KII92000.1 - 8.8e-05 22.5 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Fungal_trans PF04082.18 KII92001.1 - 1.5e-17 63.5 0.3 2.7e-17 62.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92001.1 - 7.4e-07 29.2 11.1 7.4e-07 29.2 11.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KII92001.1 - 1.4e-05 25.3 3.9 1.4e-05 25.3 3.9 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KII92001.1 - 1.5e-05 25.1 20.4 0.00083 19.7 5.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII92001.1 - 0.003 18.3 3.6 0.003 18.3 3.6 3.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII92001.1 - 0.025 14.6 6.2 0.14 12.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KII92001.1 - 0.23 11.2 7.0 0.34 10.7 1.3 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KII92001.1 - 0.55 10.6 3.4 8.2 6.9 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII92001.1 - 1.2 9.6 4.8 16 6.1 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Hydrolase_like PF13242.6 KII92002.1 - 6.3e-23 80.6 0.1 5.5e-22 77.6 0.1 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KII92002.1 - 2.1e-22 79.1 0.0 3.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII92002.1 - 0.00023 21.5 0.2 0.85 9.9 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PPR_2 PF13041.6 KII92003.1 - 0.17 12.1 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 PPR repeat family DUF3544 PF12064.8 KII92003.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 HMG_box PF00505.19 KII92004.1 - 3.7e-08 33.7 0.0 7.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Mgm101p PF06420.12 KII92006.1 - 0.071 12.6 0.1 0.095 12.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Mgm101p PF06420.12 KII92007.1 - 0.046 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 RhoGAP PF00620.27 KII92008.1 - 2.9e-29 101.9 0.0 5.6e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 KII92008.1 - 6.3e-29 100.6 0.0 1.5e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain DUF1932 PF09130.11 KII92009.1 - 1.7e-19 69.6 0.8 8.8e-19 67.3 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 KII92009.1 - 8.2e-09 35.8 0.2 1.6e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII92009.1 - 9e-05 23.0 0.4 0.00023 21.7 0.4 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KII92009.1 - 0.00037 20.1 0.1 0.00064 19.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KII92009.1 - 0.00075 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 KII92009.1 - 0.015 15.2 2.1 0.036 13.9 1.8 1.7 1 1 0 1 1 1 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 KII92009.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KII92009.1 - 0.059 13.2 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BTB PF00651.31 KII92010.1 - 0.00057 20.1 0.0 0.0023 18.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain DUF4536 PF15055.6 KII92011.1 - 0.0009 19.4 10.1 0.0042 17.3 9.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) SfLAP PF11139.8 KII92011.1 - 0.053 13.0 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF5516 PF17637.2 KII92011.1 - 0.13 12.0 0.4 0.13 12.0 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5516) F-box-like PF12937.7 KII92012.1 - 9.6e-11 41.4 0.7 2.1e-10 40.3 0.7 1.6 1 0 0 1 1 1 1 F-box-like DUF5632 PF18646.1 KII92012.1 - 0.14 12.3 0.0 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5632) YCII PF03795.14 KII92013.1 - 7.4e-10 39.1 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 YCII-related domain BTB PF00651.31 KII92013.1 - 9.2e-06 25.9 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TF_Zn_Ribbon PF08271.12 KII92013.1 - 0.033 13.7 0.1 0.091 12.3 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Phage_holin_8 PF16931.5 KII92013.1 - 0.095 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative phage holin zf-RRN7 PF11781.8 KII92013.1 - 0.22 11.2 0.6 0.54 10.0 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 SR1P PF13790.6 KII92013.1 - 2.6 8.2 4.9 0.37 10.9 0.8 1.8 2 0 0 2 2 2 0 SR1 protein F-box-like PF12937.7 KII92014.1 - 3.3e-10 39.7 3.1 5.5e-10 39.0 2.8 1.6 1 1 0 1 1 1 1 F-box-like HRDC PF00570.23 KII92014.1 - 0.048 13.6 0.9 0.076 13.0 0.9 1.3 1 0 0 1 1 1 0 HRDC domain F-box PF00646.33 KII92014.1 - 2 8.4 5.8 35 4.4 5.8 2.5 1 1 0 1 1 1 0 F-box domain ECH_1 PF00378.20 KII92015.1 - 4.2e-79 265.4 0.1 4.8e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII92015.1 - 7.8e-35 120.9 0.1 1.9e-31 109.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KII92015.1 - 0.073 13.0 0.0 0.25 11.3 0.0 1.9 1 1 1 2 2 2 0 Peptidase family S49 RNase_PH PF01138.21 KII92016.1 - 1.1e-13 51.8 0.3 2e-13 51.0 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Med12 PF09497.10 KII92017.1 - 6.8e-27 93.5 0.1 1.6e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KII92017.1 - 4.5e-05 22.5 0.0 0.00084 18.3 0.1 2.3 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DASH_Dad2 PF08654.10 KII92018.1 - 4.4e-11 43.1 0.1 5.7e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 HEAT PF02985.22 KII92019.1 - 4.1e-08 32.8 0.1 2.4 8.6 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 KII92019.1 - 2.3e-06 27.7 0.1 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KII92019.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII92019.1 - 1.9e-05 24.2 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 KII92019.1 - 4.3e-05 23.8 0.0 0.12 12.8 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KII92019.1 - 0.0013 19.2 0.0 4.7 7.8 0.0 3.4 2 0 0 2 2 2 2 HEAT-like repeat Med14 PF08638.11 KII92020.1 - 8.1e-65 217.8 0.0 8.1e-65 217.8 0.0 2.3 3 0 0 3 3 3 1 Mediator complex subunit MED14 Acetyltransf_1 PF00583.25 KII92022.1 - 1.3e-08 35.0 0.0 8.6e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII92022.1 - 1.8e-05 25.1 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII92022.1 - 5.2e-05 23.1 0.1 0.0012 18.8 0.1 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KII92022.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 KII92022.1 - 0.0012 18.7 0.0 0.023 14.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII92022.1 - 0.024 14.7 0.0 3.5 7.7 0.0 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain PEPCK_ATP PF01293.20 KII92023.1 - 3.1e-217 721.8 0.0 3.7e-217 721.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 KII92023.1 - 0.091 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KII92023.1 - 0.26 11.1 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4381 PF14316.6 KII92025.1 - 0.14 12.4 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-C3HC4_4 PF15227.6 KII92026.1 - 8.1e-07 29.1 2.1 8.1e-07 29.1 2.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KII92026.1 - 2.6e-06 27.3 3.6 2.6e-06 27.3 3.6 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII92026.1 - 5.2e-06 26.2 3.8 5.2e-06 26.2 3.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII92026.1 - 6.7e-06 25.9 3.1 6.7e-06 25.9 3.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII92026.1 - 2.3e-05 24.6 9.2 4.9e-05 23.6 4.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KII92026.1 - 0.00038 20.3 4.9 0.0056 16.5 1.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII92026.1 - 0.00045 20.1 7.2 0.0022 17.9 3.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain SEO_C PF14577.6 KII92026.1 - 0.029 13.8 0.2 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Prok-RING_4 PF14447.6 KII92026.1 - 0.031 14.1 6.4 0.16 11.9 2.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KII92026.1 - 0.036 13.7 4.7 0.08 12.6 2.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 KII92026.1 - 0.047 13.6 0.7 0.089 12.7 0.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ADIP PF11559.8 KII92026.1 - 0.061 13.4 0.7 0.83 9.7 1.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KII92026.1 - 0.069 12.3 1.6 0.1 11.8 1.6 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DZR PF12773.7 KII92026.1 - 0.077 13.0 3.0 1.6 8.9 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon ZapB PF06005.12 KII92026.1 - 0.085 13.3 0.5 0.17 12.4 0.5 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DUF1272 PF06906.11 KII92026.1 - 0.62 10.2 6.6 2.9 8.0 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 KII92026.1 - 1.1 9.6 9.6 0.64 10.4 4.9 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain XRCC4 PF06632.12 KII92026.1 - 5.8 5.7 6.0 0.23 10.2 0.2 1.5 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Git3 PF11710.8 KII92027.1 - 3e-09 37.0 8.9 6.5e-09 35.9 8.9 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KII92027.1 - 0.0052 16.8 1.2 0.0052 16.8 1.2 2.3 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KII92027.1 - 9.7 5.2 13.4 0.51 9.4 7.2 1.9 2 1 0 2 2 2 0 Slime mold cyclic AMP receptor ubiquitin PF00240.23 KII92029.1 - 1.8e-170 553.0 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KII92029.1 - 3.1e-78 257.6 27.8 4.5e-15 55.2 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KII92029.1 - 3.2e-28 98.0 13.2 0.00055 20.3 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KII92029.1 - 2e-19 69.3 5.7 0.048 13.6 0.0 5.3 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KII92029.1 - 1.5e-17 63.7 4.7 0.15 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KII92029.1 - 3.9e-17 62.4 12.4 0.064 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KII92029.1 - 6.1e-16 58.9 2.2 0.54 10.9 0.0 5.2 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KII92029.1 - 4.6e-12 46.1 0.7 1.9 8.3 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KII92029.1 - 3.9e-09 36.2 1.8 1.5 8.1 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KII92029.1 - 1.5e-07 31.3 32.7 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 KII92029.1 - 2.1e-07 31.6 0.8 39 5.1 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 KII92029.1 - 2.1e-07 31.2 0.0 41 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 KII92029.1 - 5.3e-07 29.6 0.1 41 4.4 0.0 5.7 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 KII92029.1 - 7.2e-07 29.3 5.8 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KII92029.1 - 7.3e-07 28.9 6.3 12 5.9 0.1 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KII92029.1 - 1.3e-06 28.5 5.6 9.9 6.3 0.0 5.1 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KII92029.1 - 2.8e-05 23.6 0.1 30 3.9 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) MoaF PF10703.9 KII92029.1 - 5.4e-05 23.1 0.6 0.44 10.5 0.0 5.0 5 0 0 5 5 5 1 MoaF N-terminal domain ACT_4 PF13291.6 KII92029.1 - 0.00012 22.6 3.3 76 4.0 0.0 5.2 5 0 0 5 5 5 0 ACT domain NEAT PF05031.12 KII92029.1 - 0.00028 21.5 4.1 0.72 10.5 0.8 3.4 1 1 1 2 2 2 2 Iron Transport-associated domain DUF493 PF04359.14 KII92029.1 - 0.00041 20.9 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KII92029.1 - 0.00077 19.5 0.0 1.2e+02 2.8 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KII92029.1 - 0.009 16.1 8.5 87 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KII92029.1 - 0.058 13.3 13.5 58 3.6 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KII92029.1 - 0.22 11.7 36.0 8.2 6.7 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 KII92029.1 - 0.58 10.7 12.9 68 4.0 1.2 4.9 1 1 3 4 4 4 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KII92029.1 - 2.6 8.2 7.6 3.3e+02 1.5 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR Ribosomal_S4e PF00900.20 KII92029.1 - 3.3 7.7 11.3 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e PI3K_p85B PF02192.16 KII92029.1 - 3.4 7.5 12.6 1.3e+02 2.4 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KII92029.1 - 3.5 7.8 14.4 1.4e+02 2.7 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein ACP PF06857.11 KII92029.1 - 4.1 7.7 9.6 76 3.6 0.1 5.2 5 0 0 5 5 5 0 Malonate decarboxylase delta subunit (MdcD) HMG_box PF00505.19 KII92030.1 - 3e-11 43.6 0.3 1.4e-10 41.4 0.3 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box PF00505.19 KII92032.1 - 4.5e-13 49.4 0.7 5.2e-13 49.2 0.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII92032.1 - 0.00092 19.8 0.5 0.0011 19.5 0.5 1.1 1 0 0 1 1 1 1 HMG-box domain Iron_permease PF04120.12 KII92032.1 - 0.049 13.4 0.5 0.057 13.2 0.5 1.0 1 0 0 1 1 1 0 Low affinity iron permease Nop25 PF09805.9 KII92033.1 - 3.9e-22 79.2 24.3 3.9e-22 79.2 24.3 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF4551 PF15087.6 KII92033.1 - 7 5.3 10.2 8.5 5.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) V-SNARE_C PF12352.8 KII92036.1 - 4.5e-16 58.9 0.5 4.5e-16 58.9 0.5 2.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KII92036.1 - 9.5e-07 28.7 0.3 5.5e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Sec20 PAP1 PF08601.10 KII92036.1 - 4e-05 23.5 0.2 4.9e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 Plasmid_RAQPRD PF09686.10 KII92036.1 - 0.0092 16.2 3.1 0.1 12.8 1.7 2.5 2 0 0 2 2 2 1 Plasmid protein of unknown function (Plasmid_RAQPRD) Wbp11 PF09429.10 KII92036.1 - 0.18 12.2 3.9 1.3 9.4 2.8 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 DivIVA PF05103.13 KII92036.1 - 0.24 11.5 6.4 0.13 12.4 3.3 1.9 2 0 0 2 2 2 0 DivIVA protein EMC3_TMCO1 PF01956.16 KII92036.1 - 0.47 10.2 2.7 0.66 9.7 2.7 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pkinase PF00069.25 KII92037.1 - 7.6e-13 48.4 0.0 1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92037.1 - 3.1e-08 33.2 0.0 3.5e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KII92037.1 - 8.6e-05 22.2 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KII92037.1 - 0.00057 19.9 0.1 0.00082 19.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII92037.1 - 0.0045 16.4 0.1 0.0069 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII92037.1 - 0.0049 15.7 0.1 0.0069 15.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII92037.1 - 0.058 12.7 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KII92038.1 - 5.5e-17 61.9 0.0 6.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII92038.1 - 1.6e-09 37.6 0.0 2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII92038.1 - 0.035 14.0 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Retrotran_gag_2 PF14223.6 KII92039.1 - 4.8e-06 26.3 0.0 6.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII92039.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase_Tyr PF07714.17 KII92041.1 - 7.5e-15 54.9 0.0 8.8e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII92041.1 - 4.3e-13 49.2 0.0 5.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Beta-lactamase PF00144.24 KII92041.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase Gyro_capsid PF04162.12 KII92041.1 - 0.056 11.9 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Peptidase_M28 PF04389.17 KII92043.1 - 7.1e-27 94.4 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KII92043.1 - 2.8e-08 33.7 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HMG_box PF00505.19 KII92044.1 - 2.2e-12 47.2 0.0 4.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII92044.1 - 0.0026 18.3 0.1 0.0052 17.3 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Peptidase_M28 PF04389.17 KII92045.1 - 2.7e-29 102.3 0.0 4.3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KII92045.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1856 PF08983.10 KII92047.1 - 0.033 14.4 1.2 0.054 13.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) Nup54_57_C PF18570.1 KII92047.1 - 0.64 9.7 4.6 0.1 12.2 1.0 1.6 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain DUF1664 PF07889.12 KII92052.1 - 0.021 14.8 1.2 0.053 13.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MFS18 PF17352.2 KII92052.1 - 0.17 12.3 4.6 0.33 11.3 4.6 1.4 1 0 0 1 1 1 0 Male Flower Specific protein 18 HMG_box PF00505.19 KII92053.1 - 8.3e-09 35.7 0.5 1.5e-08 34.9 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box KDZ PF18758.1 KII92056.1 - 6.1e-86 287.6 0.0 8.9e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 KII92056.1 - 0.0032 17.3 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII92056.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases MIF4G PF02854.19 KII92060.1 - 2.8e-43 148.0 0.2 1.2e-27 96.9 0.0 3.4 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 KII92060.1 - 3.3e-31 108.8 2.3 3.3e-31 108.8 2.3 3.3 3 1 0 3 3 3 1 Up-frameshift suppressor 2 LUC7 PF03194.15 KII92060.1 - 3 7.4 9.4 1.3 8.6 1.8 2.9 2 0 0 2 2 2 0 LUC7 N_terminus F-box PF00646.33 KII92062.1 - 0.0051 16.7 0.8 0.014 15.3 0.2 2.2 2 0 0 2 2 2 1 F-box domain DUF3750 PF12570.8 KII92062.1 - 0.096 13.4 1.5 3.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) F-box PF00646.33 KII92063.1 - 0.0012 18.7 0.2 0.0042 16.9 0.2 2.1 1 0 0 1 1 1 1 F-box domain Cytochrome_CBB3 PF13442.6 KII92064.1 - 0.035 14.4 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III HECW1_helix PF18436.1 KII92064.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Amidohydro_2 PF04909.14 KII92066.1 - 4.1e-07 30.1 0.0 5.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase SMN PF06003.12 KII92066.1 - 0.04 13.2 1.8 0.063 12.5 1.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) p450 PF00067.22 KII92067.1 - 8.8e-71 239.0 0.0 2.9e-53 181.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Yae1_N PF09811.9 KII92068.1 - 6.1e-08 32.2 24.9 0.00013 21.6 8.2 3.4 2 1 1 3 3 3 3 Essential protein Yae1, N terminal Golgin_A5 PF09787.9 KII92068.1 - 0.098 12.1 7.3 0.14 11.6 7.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 KII92068.1 - 0.85 9.1 6.8 1.2 8.7 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4337 PF14235.6 KII92068.1 - 5.6 7.1 15.0 0.53 10.4 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) E1-E2_ATPase PF00122.20 KII92069.1 - 5.9e-30 104.1 0.1 5.9e-30 104.1 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 KII92069.1 - 2.1e-25 89.2 0.0 4.1e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KII92069.1 - 9.6e-18 65.2 0.0 4.4e-08 33.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KII92069.1 - 1e-08 35.1 7.4 2.3e-08 33.9 7.4 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KII92069.1 - 4.9e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KII92069.1 - 4.6e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII92069.1 - 0.0095 15.7 0.1 0.096 12.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COX2-transmemb PF09125.10 KII92069.1 - 0.23 11.3 0.7 0.7 9.7 0.7 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Lactamase_B PF00753.27 KII92071.1 - 1.6e-08 34.8 0.4 3.5e-08 33.7 0.4 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KII92071.1 - 5.3e-06 26.1 0.2 7.7e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ODC_AZ PF02100.17 KII92073.1 - 2.2e-13 50.2 0.0 3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.20 KII92074.1 - 2.8e-28 97.7 0.6 2.8e-28 97.7 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KII92074.1 - 3.6e-23 80.8 0.1 6.1e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain p450 PF00067.22 KII92075.1 - 4.2e-63 213.7 0.0 5e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Form_Nir_trans PF01226.17 KII92076.1 - 1.2e-77 260.5 17.5 1.4e-77 260.2 17.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter TM_helix PF05552.12 KII92076.1 - 1.4 8.9 5.5 0.34 10.9 1.2 2.2 2 0 0 2 2 2 0 Conserved TM helix Oxidored_FMN PF00724.20 KII92078.1 - 5.9e-84 282.2 0.0 7e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_2 PF04059.12 KII92079.1 - 3.6e-33 113.7 0.5 7.4e-33 112.6 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KII92079.1 - 0.0018 18.1 0.1 0.9 9.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KII92079.1 - 0.044 14.0 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_S6 PF01250.17 KII92082.1 - 1.6e-22 79.5 0.0 2.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF5499 PF17603.2 KII92082.1 - 0.049 14.2 0.1 0.072 13.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5499) HAD_2 PF13419.6 KII92083.1 - 3.3e-14 53.4 0.0 4.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII92083.1 - 2.4e-13 50.9 0.0 3.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII92083.1 - 3.9e-07 30.1 0.0 8.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Peptidase_M28 PF04389.17 KII92083.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 SNase PF00565.17 KII92084.1 - 7.7e-60 200.1 0.8 2.7e-21 76.1 0.1 6.2 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KII92084.1 - 1.2e-20 73.8 0.0 2.3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 KII92084.1 - 0.0055 17.1 0.1 0.021 15.3 0.0 2.1 2 0 0 2 2 2 1 Agenet domain Smr PF01713.21 KII92085.1 - 4.2e-11 43.1 0.1 8.8e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KII92085.1 - 1.3e-10 41.5 1.9 4.2e-10 39.9 1.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) TFIIA PF03153.13 KII92085.1 - 0.0006 19.9 16.0 0.00065 19.8 16.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 KII92085.1 - 0.017 14.5 4.1 0.025 13.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GatB_Yqey PF02637.18 KII92085.1 - 0.043 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 GatB domain Mitofilin PF09731.9 KII92085.1 - 0.22 10.3 5.9 0.24 10.2 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 KII92085.1 - 0.81 9.6 8.4 1.1 9.1 8.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.9 KII92085.1 - 2.2 6.5 19.5 2.6 6.2 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 KII92085.1 - 4.7 5.9 6.9 5.2 5.7 6.9 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KII92085.1 - 5.6 5.5 6.6 5.8 5.5 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleo_P87 PF07267.11 KII92085.1 - 8.8 5.0 7.1 9.7 4.9 7.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Caskin-Pro-rich PF16907.5 KII92086.1 - 0.16 12.5 1.3 0.45 11.1 1.5 1.7 1 1 1 2 2 2 0 Proline rich region of Caskin proteins SGL PF08450.12 KII92087.1 - 3.8e-11 43.0 0.0 5.3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region zf-MYND PF01753.18 KII92088.1 - 1.3e-05 25.2 16.7 1.3e-05 25.2 16.7 2.3 2 0 0 2 2 2 1 MYND finger Mg_trans_NIPA PF05653.14 KII92089.1 - 2.6e-16 59.6 12.5 1.3e-08 34.4 0.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KII92089.1 - 3.5e-06 27.2 25.0 6.3e-05 23.2 8.5 3.5 3 1 0 3 3 3 2 EamA-like transporter family Tcp11 PF05794.13 KII92090.1 - 5.7e-17 61.9 0.5 7.4e-16 58.3 0.5 2.0 1 1 0 1 1 1 1 T-complex protein 11 zf-MYND PF01753.18 KII92091.1 - 1.3e-05 25.2 13.3 1.3e-05 25.2 13.3 1.9 2 0 0 2 2 2 1 MYND finger NICE-1 PF15845.5 KII92092.1 - 0.006 17.3 1.7 0.013 16.2 1.7 1.5 1 0 0 1 1 1 1 Cysteine-rich C-terminal 1 family DUF3344 PF11824.8 KII92092.1 - 0.018 14.7 0.1 0.051 13.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3344) Ssl1 PF04056.14 KII92093.1 - 2.6e-71 239.4 0.0 3.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KII92093.1 - 5.7e-15 55.3 9.5 5.7e-15 55.3 9.5 3.0 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 KII92093.1 - 8.1e-13 48.9 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KII92093.1 - 0.0007 19.2 5.6 0.58 9.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor Tfb4 VWA PF00092.28 KII92093.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain DUF4428 PF14471.6 KII92093.1 - 2.7 8.0 9.8 2.4 8.2 3.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) Dickkopf_N PF04706.12 KII92094.1 - 0.031 14.8 10.9 0.031 14.8 10.9 4.5 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region MIT_LIKE_ACTX PF17556.2 KII92094.1 - 0.049 14.2 7.5 0.058 14.0 2.5 2.9 2 0 0 2 2 2 0 MIT-like atracotoxin family DUF2207 PF09972.9 KII92094.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EB PF01683.18 KII92094.1 - 1.6 9.1 32.9 0.83 10.0 2.2 4.6 3 2 1 4 4 4 0 EB module Na_H_Exchanger PF00999.21 KII92097.1 - 4.6e-60 203.4 30.3 5.3e-60 203.2 30.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PPTA PF01239.22 KII92098.1 - 2e-08 33.7 17.5 3.1e-08 33.1 0.1 5.1 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat Glyco_hydr_30_2 PF14587.6 KII92099.1 - 2.6e-25 89.8 0.0 3.9e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Peptidase_C1_2 PF03051.15 KII92100.1 - 6.3e-157 522.8 0.0 7.3e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KII92100.1 - 1.3e-06 28.7 0.0 0.059 13.4 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 KII92100.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family SGL PF08450.12 KII92103.1 - 5.9e-09 35.9 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF1942 PF09167.11 KII92103.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Dcc1 PF09724.9 KII92104.1 - 8.2e-82 275.2 0.0 1e-81 274.9 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 G-patch_2 PF12656.7 KII92104.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 G-patch domain DUF262 PF03235.14 KII92105.1 - 5.9e-16 59.3 0.0 1.1e-15 58.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 FUSC PF04632.12 KII92106.1 - 0.00033 19.4 6.1 0.00046 18.9 6.1 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family Tho2 PF11262.8 KII92106.1 - 0.12 11.6 3.9 0.16 11.1 3.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4746 PF15928.5 KII92106.1 - 0.23 10.9 7.3 0.29 10.5 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_11 PF13086.6 KII92106.1 - 0.42 10.4 4.6 0.52 10.1 4.6 1.2 1 0 0 1 1 1 0 AAA domain VIT1 PF01988.19 KII92106.1 - 0.49 10.2 1.8 0.76 9.6 1.8 1.2 1 0 0 1 1 1 0 VIT family PvlArgDC PF01862.16 KII92106.1 - 0.63 9.8 4.0 35 4.2 5.0 2.4 2 1 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) CDC45 PF02724.14 KII92106.1 - 1.9 6.7 9.5 2.1 6.6 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 KII92106.1 - 6.4 6.8 7.4 10 6.1 7.4 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 KII92106.1 - 6.7 5.4 10.5 9.4 4.9 10.5 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 KII92107.1 - 1.8e-59 201.2 0.0 2.2e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92107.1 - 1.2e-16 60.8 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII92107.1 - 5.2e-09 36.4 0.1 1.8e-05 24.8 0.3 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII92107.1 - 0.0027 16.6 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KII92107.1 - 0.057 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sec7 PF01369.20 KII92108.1 - 1.7e-33 115.9 0.0 2.3e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KII92108.1 - 0.24 11.4 0.0 0.43 10.6 0.0 1.3 1 0 0 1 1 1 0 PH domain Flavin_Reduct PF01613.18 KII92109.1 - 3.3e-23 82.4 0.3 5e-23 81.9 0.3 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KII92109.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Fe-ADH PF00465.19 KII92110.1 - 4.4e-67 226.5 0.0 5.3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KII92110.1 - 6.6e-18 65.3 0.1 9.5e-18 64.8 0.1 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KII92111.1 - 1.4e-44 152.2 1.7 2e-44 151.7 1.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KII92111.1 - 2.6e-06 27.5 0.2 5.7e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter zf-MYND PF01753.18 KII92112.1 - 1.2e-05 25.3 12.1 2.6e-05 24.2 12.1 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KII92112.1 - 0.24 11.3 5.2 0.67 9.9 5.2 1.8 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 KII92112.1 - 3.4 8.0 8.1 7.5 7.0 8.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CHCH PF06747.13 KII92113.1 - 7.9e-07 29.1 4.5 1.2e-06 28.5 4.5 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KII92113.1 - 0.0087 16.5 2.8 0.013 15.9 2.8 1.2 1 0 0 1 1 1 1 GCK domain MCM PF00493.23 KII92114.1 - 2.4e-99 331.0 0.0 3.7e-99 330.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KII92114.1 - 3e-38 130.5 0.0 5.1e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KII92114.1 - 1.4e-34 119.6 35.5 1.4e-34 119.6 35.5 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KII92114.1 - 4.5e-25 87.9 1.1 1.5e-24 86.2 1.1 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KII92114.1 - 5.7e-13 49.4 0.0 1.7e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KII92114.1 - 2.5e-07 30.3 0.0 7.4e-06 25.5 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KII92114.1 - 7.5e-07 29.2 0.0 1.9e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KII92114.1 - 0.0011 18.9 0.1 0.015 15.2 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KII92114.1 - 0.0025 17.5 0.1 0.014 15.1 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Sorting_nexin PF03700.13 KII92114.1 - 0.015 15.9 8.0 0.031 14.9 5.4 2.6 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain Yippee-Mis18 PF03226.14 KII92114.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3128 PF11326.8 KII92115.1 - 1.4e-22 79.8 0.2 2.2e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DSPc PF00782.20 KII92117.1 - 1.9e-28 98.9 0.0 3.1e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII92117.1 - 0.0088 15.6 0.0 0.019 14.5 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KII92117.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 1 0 1 1 1 0 Rit1 DUSP-like domain COX2_TM PF02790.15 KII92118.1 - 0.0061 16.7 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain CBP_BcsF PF11120.8 KII92118.1 - 0.14 12.3 0.4 0.25 11.5 0.4 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF HemY_N PF07219.13 KII92118.1 - 0.15 12.3 2.4 0.33 11.1 2.4 1.5 1 0 0 1 1 1 0 HemY protein N-terminus DUF4218 PF13960.6 KII92119.1 - 0.0025 17.4 0.1 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4616 PF15394.6 KII92120.1 - 0.0044 16.0 0.6 0.033 13.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4616) NPV_P10 PF05531.12 KII92120.1 - 0.09 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KII92120.1 - 1.3 9.5 4.8 0.49 10.8 2.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF5583 PF17821.1 KII92121.1 - 0.057 13.4 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5583) GREB1 PF15782.5 KII92121.1 - 0.84 6.7 13.3 1.5 5.9 13.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plavaka PF18759.1 KII92122.1 - 1e-125 419.3 0.0 2.1e-125 418.3 0.0 1.6 2 0 0 2 2 2 1 Plavaka transposase YL1 PF05764.13 KII92122.1 - 3.2 7.8 7.1 5.6 7.0 7.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Peroxidase_ext PF11895.8 KII92123.1 - 2.8e-31 107.2 2.4 7.2e-31 106.0 2.4 1.7 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KII92123.1 - 1.7e-30 106.4 0.0 2.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Got1 PF04178.12 KII92125.1 - 7.8e-19 68.2 13.2 9.9e-19 67.8 13.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family CPP1-like PF11833.8 KII92125.1 - 0.29 10.7 2.4 0.37 10.4 2.4 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like U3_assoc_6 PF08640.11 KII92126.1 - 9.8e-27 92.9 0.3 1.7e-25 88.9 0.9 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KII92126.1 - 2.3e-06 27.9 8.1 0.33 11.9 0.2 6.5 3 2 2 6 6 6 2 Tetratricopeptide repeat Toxin_trans PF07952.12 KII92126.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain NRDE-2 PF08424.10 KII92126.1 - 0.031 13.4 0.1 4.4 6.3 0.0 3.0 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference Arg_decarbox_C PF17944.1 KII92126.1 - 0.16 12.6 3.2 1.1 9.8 0.9 3.2 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Adaptin_N PF01602.20 KII92127.1 - 1.7e-22 79.7 0.0 2.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 KII92127.1 - 0.0059 16.8 0.3 15 6.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KII92127.1 - 0.021 14.9 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4097 PF13349.6 KII92128.1 - 0.017 14.5 0.3 0.047 13.0 0.3 1.7 1 1 0 1 1 1 0 Putative adhesin ICMT PF04140.14 KII92132.1 - 9.1e-15 54.9 0.6 9.1e-13 48.5 0.0 2.4 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII92132.1 - 2.6e-13 50.3 3.3 8.7e-12 45.4 0.1 2.2 1 1 1 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII92132.1 - 3.1e-06 26.2 0.1 4.1e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KII92132.1 - 0.059 12.9 0.2 0.086 12.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DUF3188 PF11384.8 KII92132.1 - 0.067 12.9 0.6 0.26 11.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) ICMT PF04140.14 KII92133.1 - 4.7e-14 52.6 0.3 1.6e-12 47.7 0.3 2.4 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII92133.1 - 2.8e-13 50.2 1.1 1.3e-12 48.1 0.2 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII92133.1 - 9.8e-07 27.9 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3188 PF11384.8 KII92133.1 - 0.0011 18.6 1.7 0.0031 17.2 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3188) DUF1295 PF06966.12 KII92133.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) ICMT PF04140.14 KII92135.1 - 8.5e-15 55.0 1.1 3.7e-13 49.7 0.1 2.4 1 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII92135.1 - 4.4e-13 49.5 1.8 4.6e-12 46.3 0.2 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KII92135.1 - 4.6e-06 25.7 0.0 6.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KII92135.1 - 0.0015 18.1 0.1 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_L11_N PF03946.14 KII92136.1 - 2.5e-23 81.7 0.2 3.9e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KII92136.1 - 2.5e-18 66.3 0.7 4.5e-18 65.5 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.11 KII92137.1 - 7.6e-29 101.2 1.3 4e-28 98.8 0.1 2.4 2 1 1 3 3 3 1 Cyclin Cyclin_N PF00134.23 KII92137.1 - 4.6e-05 23.2 0.1 7.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ADH_zinc_N_2 PF13602.6 KII92137.1 - 0.097 13.7 0.0 0.15 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 KII92138.1 - 2.2e-16 59.7 36.6 1.9e-15 56.7 33.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KII92140.1 - 3.4e-34 118.4 0.0 1.5e-32 113.0 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92140.1 - 1.8e-17 63.5 0.0 3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII92140.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KII92140.1 - 0.017 15.1 0.3 0.06 13.3 0.2 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family NAD_binding_10 PF13460.6 KII92141.1 - 2.3e-07 30.9 0.2 5.1e-07 29.8 0.2 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII92141.1 - 4.3e-07 29.7 0.0 2.7e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KII92141.1 - 1e-05 25.3 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KII92141.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KII92141.1 - 0.01 16.3 0.1 0.033 14.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KII92141.1 - 0.056 14.1 0.6 2 9.1 0.0 2.6 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KII92141.1 - 0.18 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein RabGAP-TBC PF00566.18 KII92142.1 - 4.5e-38 131.1 0.1 6.9e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBF PF01758.16 KII92144.1 - 2.2e-50 171.1 12.8 4.9e-50 169.9 12.8 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family NmrA PF05368.13 KII92145.1 - 1.9e-08 34.2 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KII92145.1 - 2.4e-08 34.1 0.2 4e-08 33.4 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KII92145.1 - 0.0002 20.9 0.1 0.057 12.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII92145.1 - 0.0021 17.3 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 KII92145.1 - 0.0054 17.2 0.0 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII92145.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KII92145.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peroxidase_ext PF11895.8 KII92147.1 - 6e-32 109.4 1.4 1.2e-31 108.4 1.4 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KII92147.1 - 3e-30 105.6 0.0 4.7e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.19 KII92149.1 - 1.8e-28 99.8 0.0 2.2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII92149.1 - 6.8e-06 25.5 0.7 0.0021 17.4 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII92149.1 - 7e-05 22.6 0.4 0.017 14.7 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase SE PF08491.10 KII92149.1 - 0.0028 16.7 0.0 0.79 8.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox PF00070.27 KII92149.1 - 0.0041 17.6 0.4 0.024 15.2 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII92149.1 - 0.032 13.5 0.8 0.054 12.7 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase bZIP_1 PF00170.21 KII92150.1 - 2.9e-05 24.1 3.2 2.9e-05 24.1 3.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KII92150.1 - 0.0011 19.0 5.7 0.0028 17.7 5.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.15 KII92150.1 - 0.046 13.5 1.3 0.097 12.5 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 KII92150.1 - 0.05 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family HALZ PF02183.18 KII92150.1 - 0.11 12.7 1.9 0.23 11.7 1.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper CotE PF10628.9 KII92151.1 - 0.0028 17.3 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Outer spore coat protein E (CotE) IU_nuc_hydro PF01156.19 KII92152.1 - 5.9e-60 203.4 0.0 7.8e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.32 KII92153.1 - 2.3e-42 142.2 26.2 1.6e-08 35.0 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII92153.1 - 3.8e-08 33.5 1.0 0.095 13.0 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KII92153.1 - 0.00047 18.9 5.6 0.043 12.5 0.2 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KII92153.1 - 0.00079 18.6 0.0 0.14 11.2 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.12 KII92153.1 - 0.0024 17.7 1.5 5.9 7.0 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KII92153.1 - 0.004 15.7 0.1 0.81 8.1 0.2 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain DUF1416 PF07210.12 KII92153.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Med1 PF10744.9 KII92157.1 - 0.19 10.7 0.0 17 4.3 0.0 2.4 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription subunit 1 D123 PF07065.14 KII92158.1 - 3.1e-98 328.7 0.0 3.6e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 D123 Filament PF00038.21 KII92159.1 - 0.032 13.8 0.0 0.039 13.5 0.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein Lectin_N PF03954.14 KII92159.1 - 0.32 10.8 1.5 0.28 10.9 0.2 1.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Dynamitin PF04912.14 KII92161.1 - 2.6e-63 214.7 0.0 4.1e-63 214.0 0.0 1.3 1 1 0 1 1 1 1 Dynamitin Laminin_II PF06009.12 KII92161.1 - 0.033 14.2 0.1 0.093 12.7 0.1 1.8 1 0 0 1 1 1 0 Laminin Domain II EzrA PF06160.12 KII92161.1 - 0.12 10.6 0.1 0.2 9.8 0.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HOOK PF05622.12 KII92161.1 - 0.15 10.2 0.2 0.23 9.5 0.2 1.3 1 0 0 1 1 1 0 HOOK protein COG2 PF06148.11 KII92161.1 - 0.65 10.1 2.9 0.53 10.4 0.2 2.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 KII92161.1 - 0.82 10.3 8.0 1.1 10.0 0.1 3.8 5 0 0 5 5 5 0 SlyX SNF2_N PF00176.23 KII92162.1 - 1.8e-55 188.1 0.0 2.9e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII92162.1 - 5.3e-13 49.3 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII92162.1 - 9.2e-10 38.8 0.0 2.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2439 PF10382.9 KII92162.1 - 1.7e-07 31.4 0.3 0.01 16.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) Rad54_N PF08658.10 KII92162.1 - 3.5e-05 24.0 0.4 3.5e-05 24.0 0.4 1.9 2 0 0 2 2 2 1 Rad54 N terminal HDA2-3 PF11496.8 KII92162.1 - 0.0088 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 XPG_I PF00867.18 KII92167.1 - 8.4e-19 67.7 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 KII92167.1 - 1.2e-18 68.0 2.3 1.2e-18 68.0 2.3 3.9 3 2 1 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 KII92167.1 - 2.2e-05 24.8 0.0 6.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain AAA PF00004.29 KII92170.1 - 1.8e-08 34.9 0.0 7e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII92170.1 - 2.3e-05 24.8 0.0 4.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KII92170.1 - 4.2e-05 22.8 0.0 0.00046 19.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 KII92170.1 - 0.00095 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KII92170.1 - 0.0049 16.5 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KII92170.1 - 0.017 14.5 0.0 0.83 9.0 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KII92170.1 - 0.029 14.3 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KII92170.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KII92170.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KII92170.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 KII92171.1 - 1.8e-10 40.6 0.9 7.4e-10 38.6 0.9 2.2 1 0 0 1 1 1 1 F-box-like Asparaginase_2 PF01112.18 KII92172.1 - 4e-73 246.1 0.0 3.8e-72 242.9 0.0 2.1 1 1 0 1 1 1 1 Asparaginase Ricin_B_lectin PF00652.22 KII92173.1 - 0.012 15.8 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 KII92174.1 - 0.0062 16.8 0.2 0.0092 16.2 0.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CMAS PF02353.20 KII92175.1 - 1.7e-33 116.1 0.0 2.3e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII92175.1 - 1.7e-14 54.3 0.0 3.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII92175.1 - 1.9e-12 47.7 0.0 4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII92175.1 - 4.5e-11 42.8 0.0 8.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII92175.1 - 2.5e-10 41.0 0.0 5.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII92175.1 - 6.5e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII92175.1 - 4.7e-08 32.8 0.0 8.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 KII92175.1 - 7.3e-06 25.2 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KII92175.1 - 1.7e-05 24.3 0.0 3.7e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 KII92175.1 - 6.2e-05 22.5 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 KII92175.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KII92175.1 - 0.0031 17.7 0.0 0.02 15.0 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 KII92175.1 - 0.0056 16.5 0.1 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF938) NodS PF05401.11 KII92175.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 KII92175.1 - 0.014 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GidB PF02527.15 KII92175.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.19 KII92175.1 - 0.043 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KII92175.1 - 0.043 13.8 0.2 0.087 12.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Sirohm_synth_C PF14823.6 KII92175.1 - 0.098 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal MDM31_MDM32 PF08118.11 KII92176.1 - 7.8e-198 658.4 0.0 2.6e-196 653.4 0.0 2.1 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DNase_NucA_NucB PF14040.6 KII92176.1 - 0.14 12.5 1.0 0.36 11.2 0.3 1.9 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Ribosomal_S7 PF00177.21 KII92178.1 - 2.8e-36 124.4 1.3 3.4e-36 124.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CBM64 PF18666.1 KII92179.1 - 0.04 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 64 zinc_ribbon_11 PF11682.8 KII92179.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon Pex24p PF06398.11 KII92180.1 - 3.5e-35 121.7 0.1 1.4e-34 119.7 0.1 1.9 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SNF2_N PF00176.23 KII92184.1 - 5.4e-63 212.8 0.0 8.2e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KII92184.1 - 2.2e-19 69.2 0.0 4.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KII92184.1 - 1.5e-16 61.0 0.0 3.5e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 KII92184.1 - 1.9e-13 50.7 0.0 1.1e-06 29.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KII92184.1 - 5.5e-09 36.3 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KII92184.1 - 1.5e-08 34.3 6.9 3.1e-08 33.3 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII92184.1 - 2.2e-07 30.6 7.1 4.6e-07 29.6 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KII92184.1 - 4e-06 26.7 0.1 1.1e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KII92184.1 - 1.3e-05 25.1 3.6 2.4e-05 24.2 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KII92184.1 - 2.4e-05 24.4 7.7 5.4e-05 23.3 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KII92184.1 - 2.5e-05 24.0 6.3 5.2e-05 23.0 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII92184.1 - 4.2e-05 23.8 6.5 9.7e-05 22.6 6.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII92184.1 - 7.3e-05 22.7 9.2 0.00017 21.5 9.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KII92184.1 - 0.0082 16.4 5.5 0.031 14.6 5.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KII92184.1 - 0.22 11.4 7.5 0.3 11.0 6.4 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KII92184.1 - 0.59 10.3 3.2 1.3 9.2 3.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Nse4_C PF08743.10 KII92185.1 - 6.8e-33 112.8 2.0 1.4e-32 111.8 0.0 2.3 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KII92185.1 - 8.2e-19 67.5 1.2 1.9e-18 66.3 1.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE MRP-S31 PF15433.6 KII92185.1 - 0.34 10.5 5.9 2.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Sec7 PF01369.20 KII92186.1 - 2.4e-18 66.5 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain APH PF01636.23 KII92186.1 - 4.1e-08 33.4 1.8 3.9e-06 27.0 1.7 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KII92186.1 - 4.6e-06 26.2 0.0 6.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KII92186.1 - 1.8e-05 24.5 0.1 2.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KII92186.1 - 0.00028 20.3 0.1 0.00053 19.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII92186.1 - 0.00088 18.9 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KII92186.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase ARPC4 PF05856.12 KII92187.1 - 5.6e-79 263.6 5.7 6.2e-79 263.4 5.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 KII92187.1 - 0.18 12.3 1.6 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FKBP_C PF00254.28 KII92188.1 - 5.7e-31 106.7 0.0 1.7e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KII92188.1 - 1.8e-25 89.5 0.0 1.8e-25 89.5 0.0 2.4 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 KII92188.1 - 0.0051 17.0 19.3 0.01 16.0 19.3 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Acetyltransf_3 PF13302.7 KII92189.1 - 1.5e-18 67.8 0.0 2.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII92189.1 - 6.4e-09 36.1 0.0 9.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII92189.1 - 0.0012 19.2 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII92189.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PX PF00787.24 KII92191.1 - 3.4e-26 91.5 0.1 5.4e-26 90.8 0.0 1.3 2 0 0 2 2 2 1 PX domain Trs65 PF12735.7 KII92192.1 - 1.8e-25 90.1 0.3 2.3e-14 53.5 0.1 3.3 2 1 1 3 3 3 3 TRAPP trafficking subunit Trs65 Ras PF00071.22 KII92194.1 - 2.1e-34 118.5 0.0 2.4e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII92194.1 - 3.6e-06 27.2 0.0 8.8e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KII92194.1 - 0.01 15.3 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DLIC PF05783.11 KII92194.1 - 0.13 11.0 0.0 17 4.1 0.0 2.6 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) Ras PF00071.22 KII92195.1 - 3.8e-34 117.6 0.0 4.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII92195.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KII92195.1 - 0.0053 16.3 0.0 0.66 9.5 0.0 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B AAA_14 PF13173.6 KII92195.1 - 0.061 13.4 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4199 PF13858.6 KII92195.1 - 0.17 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Septin PF00735.18 KII92196.1 - 0.2 10.9 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Septin HSP70 PF00012.20 KII92197.1 - 2.4e-163 544.6 0.4 2.4e-163 544.6 0.4 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KII92197.1 - 4.3e-11 42.2 2.6 7.1e-11 41.5 0.1 2.3 3 0 0 3 3 3 1 MreB/Mbl protein IPK PF03770.16 KII92197.1 - 4.1 7.2 9.6 7.2 6.4 0.5 3.4 3 1 1 4 4 4 0 Inositol polyphosphate kinase Ras PF00071.22 KII92198.1 - 1.9e-39 134.8 0.0 2.2e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII92198.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KII92198.1 - 0.0015 18.1 0.0 0.038 13.5 0.0 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KII92198.1 - 0.0022 18.4 0.0 0.003 18.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KII92198.1 - 0.043 13.3 0.6 4.3 6.8 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Glyco_tranf_2_3 PF13641.6 KII92200.1 - 3.1e-31 109.0 0.0 4.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KII92200.1 - 1.3e-09 38.1 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KII92200.1 - 1.7e-06 27.6 0.0 7.7e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KII92200.1 - 0.0065 16.4 5.6 0.013 15.4 5.6 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 IBR PF01485.21 KII92201.1 - 1.9e-16 60.0 39.2 4e-09 36.6 17.2 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KII92201.1 - 1.4e-05 24.8 3.9 1.4e-05 24.8 3.9 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII92201.1 - 5e-05 23.1 2.8 5e-05 23.1 2.8 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII92201.1 - 0.00023 21.1 4.0 0.00023 21.1 4.0 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII92201.1 - 0.001 18.9 2.8 0.001 18.9 2.8 3.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII92201.1 - 0.0022 18.3 4.5 0.0022 18.3 4.5 3.9 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_4 PF15227.6 KII92201.1 - 0.0098 16.0 2.9 0.0098 16.0 2.9 4.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING tRNA-synt_2 PF00152.20 KII92202.1 - 7.3e-77 258.5 0.0 9.5e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KII92202.1 - 1e-12 47.9 0.3 8.6e-12 44.9 0.0 2.5 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KII92202.1 - 1.8e-09 37.4 0.0 4.2e-05 23.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) AbiGii_2 PF16873.5 KII92202.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGii toxin IHABP4_N PF16174.5 KII92202.1 - 0.18 12.4 8.9 0.25 11.9 4.0 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal PC-Esterase PF13839.6 KII92203.1 - 3.2e-06 27.1 0.0 0.081 12.7 0.1 2.2 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Use1 PF09753.9 KII92204.1 - 1.2e-19 71.0 0.1 1.6e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 MCU PF04678.13 KII92204.1 - 0.1 12.7 0.4 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Sec20 PF03908.13 KII92204.1 - 0.7 9.8 3.0 1.6 8.7 1.0 2.3 2 1 0 2 2 2 0 Sec20 Use1 PF09753.9 KII92205.1 - 1.9e-08 34.4 1.0 2.2e-08 34.1 1.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Phage_1_1 PF08200.11 KII92206.1 - 0.11 13.0 2.4 0.54 10.7 2.4 2.3 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein TipAS PF07739.13 KII92206.1 - 2 9.0 4.3 9.3 6.8 0.2 3.1 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain CHASE3 PF05227.13 KII92206.1 - 3.7 7.5 7.3 1.5 8.8 0.9 2.4 2 0 0 2 2 2 0 CHASE3 domain DndE PF08870.11 KII92208.1 - 0.075 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA sulphur modification protein DndE KDZ PF18758.1 KII92210.1 - 1.5e-75 253.6 0.0 3.3e-75 252.5 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF3699 PF12480.8 KII92210.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Ig_mannosidase PF17753.1 KII92211.1 - 3.2e-17 62.0 0.4 1.3e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 KII92211.1 - 3.1e-10 40.5 1.6 8.2e-10 39.2 1.6 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain PHD_2 PF13831.6 KII92213.1 - 0.0016 18.0 2.2 0.0033 17.0 2.2 1.5 1 0 0 1 1 1 1 PHD-finger zinc_ribbon_10 PF10058.9 KII92213.1 - 0.05 13.3 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Ig_mannosidase PF17753.1 KII92215.1 - 2.2e-06 27.3 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 KII92216.1 - 1e-10 42.0 1.1 3.1e-10 40.5 1.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KII92216.1 - 2.4e-05 24.0 0.1 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KII92216.1 - 0.029 15.0 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Phage_fiber_2 PF03406.13 KII92216.1 - 0.12 12.0 0.4 0.32 10.6 0.4 1.7 1 0 0 1 1 1 0 Phage tail fibre repeat R3H PF01424.22 KII92217.1 - 3.3e-13 49.4 0.0 9.3e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KII92217.1 - 3.2e-08 33.3 0.1 9.2e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KII92217.1 - 0.00086 19.4 0.1 0.00086 19.4 0.1 2.8 3 0 0 3 3 3 1 G-patch domain Stm1_N PF09598.10 KII92217.1 - 0.074 13.9 0.3 0.074 13.9 0.3 4.5 4 1 0 4 4 4 0 Stm1 RF-1 PF00472.20 KII92220.1 - 2.3e-23 82.4 0.7 3.1e-23 81.9 0.7 1.1 1 0 0 1 1 1 1 RF-1 domain ALS_ss_C PF10369.9 KII92221.1 - 3.2e-18 65.7 0.1 3e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KII92221.1 - 5.7e-13 48.4 0.0 1.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KII92221.1 - 2.5e-07 30.4 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain DUF2187 PF09953.9 KII92221.1 - 0.066 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) Pkinase PF00069.25 KII92222.1 - 3.5e-57 193.8 0.0 3.8e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92222.1 - 2.7e-29 102.3 0.0 3.3e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII92222.1 - 4.6e-11 42.6 0.0 7.7e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII92222.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII92222.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII92222.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KII92222.1 - 0.06 13.0 0.0 0.24 11.0 0.0 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KII92222.1 - 0.082 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GATase_5 PF13507.6 KII92223.1 - 4.6e-100 334.0 0.0 6.4e-100 333.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KII92223.1 - 9.4e-43 146.0 1.7 3.1e-29 102.1 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KII92223.1 - 2.2e-32 111.4 0.0 5.1e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KII92223.1 - 1.9e-21 76.3 0.0 5.1e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Aldo_ket_red PF00248.21 KII92224.1 - 9.1e-74 248.3 0.0 1e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CMAS PF02353.20 KII92225.1 - 5.6e-61 206.2 0.0 1.3e-60 205.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII92225.1 - 7.6e-10 39.4 0.0 1.6e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII92225.1 - 4.7e-08 33.6 0.0 9.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII92225.1 - 2.3e-07 30.8 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII92225.1 - 6.9e-05 23.5 0.0 0.00014 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII92225.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KII92225.1 - 0.0051 16.6 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KII92225.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 KII92225.1 - 0.03 14.1 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KII92225.1 - 0.052 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KII92225.1 - 0.086 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Abhydrolase_6 PF12697.7 KII92226.1 - 2.5e-16 61.0 0.2 3e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII92226.1 - 0.026 14.2 0.0 0.028 14.1 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3759 PF12585.8 KII92227.1 - 0.0094 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) COG5 PF10392.9 KII92228.1 - 2.2e-24 86.1 2.3 2.2e-13 50.5 0.0 3.9 3 0 0 3 3 3 2 Golgi transport complex subunit 5 Vps51 PF08700.11 KII92228.1 - 7.3e-05 22.8 0.0 0.00064 19.7 0.0 2.7 1 1 0 1 1 1 1 Vps51/Vps67 NAD_kinase PF01513.21 KII92229.1 - 4e-72 242.9 0.0 7.5e-72 242.0 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase NOA36 PF06524.12 KII92229.1 - 0.093 12.0 4.3 0.17 11.1 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein YqeY PF09424.10 KII92231.1 - 1.5e-24 86.7 0.1 1.9e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Yqey-like protein ParB PF08775.10 KII92231.1 - 0.041 14.4 0.2 0.075 13.5 0.2 1.4 1 0 0 1 1 1 0 ParB family zf-rbx1 PF12678.7 KII92232.1 - 1.9e-11 44.0 2.8 3.8e-11 43.1 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KII92232.1 - 1.6e-08 34.7 8.9 6.5e-08 32.8 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII92232.1 - 5.8e-07 29.3 2.9 1.2e-06 28.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII92232.1 - 4.1e-06 26.5 4.2 1e-05 25.3 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII92232.1 - 5.5e-06 26.3 2.6 1.1e-05 25.4 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KII92232.1 - 7.9e-05 22.6 0.4 0.00018 21.5 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KII92232.1 - 0.00013 21.8 1.2 0.00025 20.8 1.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KII92232.1 - 0.00017 21.3 4.6 0.0012 18.6 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KII92232.1 - 0.00076 19.1 0.5 0.0017 18.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KII92232.1 - 0.00095 19.1 3.9 0.0031 17.4 4.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 KII92232.1 - 0.0058 16.3 0.6 0.0058 16.3 0.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KII92232.1 - 0.015 15.4 1.7 0.031 14.4 1.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KII92232.1 - 0.08 13.1 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KII92232.1 - 0.39 11.1 2.4 0.77 10.1 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KII92232.1 - 3.5 7.5 4.4 1.2 8.9 1.5 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.11 KII92233.1 - 1.4e-83 282.0 0.0 1.7e-83 281.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KII92233.1 - 9.2e-11 41.6 0.0 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Skp1_POZ PF03931.15 KII92233.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Con-6 PF10346.9 KII92234.1 - 2e-46 155.7 11.0 3.5e-15 55.7 0.7 3.1 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 KII92234.1 - 0.063 13.1 2.6 3.6 7.4 0.1 2.5 2 1 0 2 2 2 0 SpoIIIAH-like protein HbrB PF08539.11 KII92235.1 - 3.3e-56 189.9 0.0 6.6e-56 188.9 0.0 1.5 1 0 0 1 1 1 1 HbrB-like Pkinase PF00069.25 KII92237.1 - 3.6e-67 226.5 0.0 4.9e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92237.1 - 7.9e-45 153.2 0.0 1.2e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII92237.1 - 4.2e-09 36.1 0.0 8.3e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KII92237.1 - 0.0008 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII92237.1 - 0.0041 16.0 0.2 0.0068 15.2 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KII92237.1 - 0.02 13.9 0.0 0.05 12.5 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 KII92237.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KII92237.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MBD_C PF14048.6 KII92239.1 - 0.088 13.5 0.3 0.11 13.2 0.3 1.5 1 1 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Vut_1 PF02592.15 KII92240.1 - 0.057 13.7 0.3 0.063 13.6 0.3 1.1 1 0 0 1 1 1 0 Putative vitamin uptake transporter ABC_membrane PF00664.23 KII92241.1 - 2e-35 122.8 4.4 3e-35 122.2 4.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KII92241.1 - 3.4e-33 115.1 0.0 5.8e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KII92241.1 - 3.5e-05 23.4 0.1 0.00038 20.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII92241.1 - 0.0015 19.0 0.4 0.0046 17.3 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII92241.1 - 0.0046 17.2 0.1 0.075 13.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KII92241.1 - 0.0082 15.9 0.2 0.025 14.3 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KII92241.1 - 0.012 15.5 0.1 0.039 13.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KII92241.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KII92241.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MTABC_N PF16185.5 KII92241.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.8 4 0 0 4 4 4 0 Mitochondrial ABC-transporter N-terminal five TM region FAST_2 PF08368.12 KII92241.1 - 0.13 13.1 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Zeta_toxin PF06414.12 KII92241.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 KII92241.1 - 0.15 12.5 0.1 2.7 8.4 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KII92241.1 - 0.16 12.1 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RRM_1 PF00076.22 KII92242.1 - 8.5e-24 83.2 0.0 1.1e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII92242.1 - 0.0033 17.5 0.0 0.0057 16.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif HMG_box PF00505.19 KII92243.1 - 3.9e-14 52.8 1.7 5.8e-14 52.3 1.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII92243.1 - 4.3e-06 27.2 0.2 5.7e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 HMG-box domain DUF21 PF01595.20 KII92244.1 - 0.14 11.8 0.6 0.2 11.3 0.6 1.2 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Glyco_hydro_16 PF00722.21 KII92245.1 - 2.3e-07 30.5 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HMMR_C PF15908.5 KII92246.1 - 1.9e-05 25.0 3.7 1.9e-05 25.0 3.7 4.2 3 2 2 5 5 5 1 Hyaluronan mediated motility receptor C-terminal SHIPPO-rpt PF07004.12 KII92246.1 - 0.00016 22.5 0.2 0.12 13.4 0.1 2.6 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat Tup_N PF08581.10 KII92246.1 - 0.0081 16.5 0.1 0.0081 16.5 0.1 4.6 5 0 0 5 5 5 1 Tup N-terminal TolA_bind_tri PF16331.5 KII92246.1 - 0.063 13.4 0.4 0.063 13.4 0.4 6.9 6 1 1 7 7 7 0 TolA binding protein trimerisation NIF PF03031.18 KII92247.1 - 2.5e-55 186.5 0.1 3e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KII92247.1 - 0.0035 17.8 0.1 0.038 14.4 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SPX PF03105.19 KII92248.1 - 0.65 9.9 12.9 0.85 9.5 12.9 1.1 1 0 0 1 1 1 0 SPX domain PTPLA PF04387.14 KII92249.1 - 8.2e-55 185.0 4.4 1.5e-54 184.2 4.4 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Asp PF00026.23 KII92250.1 - 2.4e-69 234.2 3.8 2.4e-69 234.2 3.8 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII92250.1 - 6.4e-10 39.6 14.2 6.1e-07 29.8 0.2 3.9 2 2 2 4 4 4 2 Xylanase inhibitor N-terminal RPA43_OB PF17875.1 KII92251.1 - 7.9e-28 97.6 0.0 7.9e-28 97.6 0.0 3.3 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KII92251.1 - 5.4e-09 36.3 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pam16 PF03656.13 KII92252.1 - 3.7e-20 72.2 0.0 9.6e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Pam16 DUF3619 PF12279.8 KII92253.1 - 0.0032 17.8 3.9 0.0032 17.8 3.9 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3619) Fib_alpha PF08702.10 KII92253.1 - 0.017 15.3 12.8 0.063 13.5 7.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 KII92253.1 - 0.15 12.0 12.2 0.5 10.4 4.7 2.5 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 KII92253.1 - 1.2 7.9 24.4 4.1 6.2 24.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein BRE1 PF08647.11 KII92253.1 - 6.7 6.9 23.6 0.81 9.8 15.8 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase PPR_3 PF13812.6 KII92256.1 - 7.4e-41 138.1 0.2 1.3e-09 37.9 0.0 6.4 6 2 2 8 8 8 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 KII92256.1 - 1.5e-38 130.8 2.5 3.2e-09 36.8 0.0 7.9 5 3 3 8 8 8 7 PPR repeat family PPR_long PF17177.4 KII92256.1 - 2.5e-22 79.3 0.0 1.9e-06 27.4 0.0 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KII92256.1 - 7.5e-16 57.2 10.8 5.4e-05 23.2 0.3 7.5 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.7 KII92256.1 - 1.5e-12 47.0 2.1 0.0015 18.2 0.0 6.7 7 0 0 7 7 7 3 PPR repeat ECSIT PF06239.11 KII92256.1 - 0.0023 17.1 0.1 15 4.7 0.0 4.3 4 1 1 5 5 5 2 Evolutionarily conserved signalling intermediate in Toll pathway Exog_C PF18026.1 KII92256.1 - 0.028 14.4 0.0 15 5.7 0.0 4.0 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain Rad21_Rec8_N PF04825.13 KII92257.1 - 3.2e-38 130.3 0.2 5.7e-38 129.5 0.2 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KII92257.1 - 4.6e-13 48.2 0.1 8.4e-13 47.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein BTB PF00651.31 KII92258.1 - 1.5e-11 44.5 0.0 7.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Apt1 PF10351.9 KII92258.1 - 0.14 10.9 0.3 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RhoGAP PF00620.27 KII92259.1 - 5.1e-43 146.5 0.2 4e-42 143.6 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KII92259.1 - 1.3e-11 44.5 26.8 4.5e-07 30.0 8.3 2.9 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 KII92259.1 - 6.6e-07 29.1 7.1 6.6e-07 29.1 7.1 3.6 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KII92259.1 - 7.8e-05 22.9 1.6 7.8e-05 22.9 1.6 3.8 3 1 0 3 3 3 1 C1 domain RICH PF05062.12 KII92259.1 - 0.022 15.1 2.8 4.9 7.6 0.5 2.7 2 0 0 2 2 2 0 RICH domain YabA PF06156.13 KII92259.1 - 0.25 12.0 6.0 1.9 9.1 0.1 3.6 3 0 0 3 3 3 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KII92259.1 - 0.91 9.8 19.6 0.51 10.6 1.8 3.6 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YlqD PF11068.8 KII92259.1 - 2.9 8.3 10.4 0.026 14.9 1.3 2.2 2 0 0 2 2 2 0 YlqD protein KTI12 PF08433.10 KII92260.1 - 1.1e-81 274.2 0.0 1.3e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KII92260.1 - 1.8e-06 28.2 0.0 3.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF3419 PF11899.8 KII92261.1 - 1.2e-140 469.1 0.0 1.5e-140 468.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 KII92261.1 - 3e-10 40.6 0.0 4.4e-08 33.7 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII92261.1 - 2.4e-09 37.2 0.0 6.3e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII92261.1 - 1.6e-08 35.1 0.0 2.7e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KII92261.1 - 6e-08 33.3 0.0 8.8e-06 26.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII92261.1 - 2.7e-07 30.2 0.0 3.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KII92261.1 - 1.5e-05 24.9 0.0 8e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KII92261.1 - 0.021 14.3 0.0 0.062 12.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 KII92261.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain zf-MYND PF01753.18 KII92262.1 - 1.1e-08 35.1 10.9 1.6e-08 34.4 10.9 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII92262.1 - 0.0046 17.2 10.1 0.0083 16.4 10.1 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding MCM_bind PF09739.9 KII92265.1 - 0.079 11.4 7.8 0.11 10.9 7.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 KII92265.1 - 9.9 5.9 15.1 15 5.3 15.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hist_deacetyl PF00850.19 KII92267.1 - 1.1e-89 301.0 0.0 1.5e-89 300.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KII92267.1 - 9.9e-38 129.7 0.0 1.5e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain DUF1749 PF08538.10 KII92267.1 - 0.002 17.3 0.0 0.0052 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) DUF3089 PF11288.8 KII92267.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lactamase_B PF00753.27 KII92268.1 - 2.6e-11 43.9 0.2 5.2e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KII92268.1 - 0.00012 21.7 0.1 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Amidohydro_1 PF01979.20 KII92269.1 - 5.2e-13 49.0 0.1 1e-10 41.5 0.1 3.2 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KII92269.1 - 2.5e-12 47.0 0.8 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Rad10 PF03834.14 KII92270.1 - 2e-45 153.5 0.0 2.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KII92270.1 - 2.5e-08 34.4 0.0 4.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain MFS_1 PF07690.16 KII92272.1 - 1.9e-37 129.0 28.4 1.9e-37 129.0 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII92272.1 - 9.2e-11 41.2 10.3 9.2e-11 41.2 10.3 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter QCR10 PF09796.9 KII92272.1 - 8.2 6.6 9.4 0.68 10.0 0.8 3.5 3 1 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Amidohydro_3 PF07969.11 KII92273.1 - 4.4e-11 42.9 2.2 1.5e-06 28.0 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KII92273.1 - 2.2e-10 40.4 0.0 4e-08 33.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family TRP PF06011.12 KII92274.1 - 3.1e-77 260.1 16.8 4.8e-77 259.5 16.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KII92274.1 - 4.1e-27 95.2 0.5 4.1e-27 95.2 0.5 1.6 2 0 0 2 2 2 1 ML-like domain OPT PF03169.15 KII92275.1 - 9.2e-157 523.3 42.9 1e-156 523.2 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2182 PF09948.9 KII92275.1 - 0.16 11.9 4.7 0.64 9.9 0.1 2.8 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) OSCP PF00213.18 KII92277.1 - 2.1e-39 135.4 2.2 2.4e-39 135.2 2.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pre-SET PF05033.16 KII92279.1 - 1.7e-20 73.7 5.4 1.7e-20 73.7 5.4 2.5 2 1 0 2 2 2 1 Pre-SET motif SET PF00856.28 KII92279.1 - 5.5e-18 65.9 0.4 2.4e-17 63.8 0.4 2.0 1 1 0 1 1 1 1 SET domain MgsA_C PF12002.8 KII92280.1 - 1.3e-53 181.4 0.1 2.1e-53 180.7 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KII92280.1 - 3.1e-18 65.9 1.3 4.4e-18 65.4 0.3 1.8 2 0 0 2 2 1 1 AAA C-terminal domain RuvB_N PF05496.12 KII92280.1 - 2.8e-16 59.7 0.0 1.5e-15 57.3 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KII92280.1 - 5.3e-16 59.2 0.1 1.6e-15 57.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KII92280.1 - 8.1e-08 32.4 0.1 1.4e-06 28.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII92280.1 - 1.1e-07 32.3 0.2 0.0005 20.5 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KII92280.1 - 7.5e-06 25.7 0.0 0.0004 20.1 0.1 2.4 1 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KII92280.1 - 8.5e-06 25.3 0.2 0.058 12.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KII92280.1 - 6.8e-05 23.2 0.0 0.0021 18.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KII92280.1 - 0.00025 21.6 0.0 0.00058 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 KII92280.1 - 0.00053 19.8 0.0 0.046 13.5 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 KII92280.1 - 0.0009 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KII92280.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KII92280.1 - 0.0017 18.4 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII92280.1 - 0.0017 18.5 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KII92280.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.15 KII92280.1 - 0.0055 16.6 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 KII92280.1 - 0.0089 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KII92280.1 - 0.032 14.8 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KII92280.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 KII92280.1 - 0.055 13.4 0.0 4 7.3 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea SKI PF01202.22 KII92280.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.22 KII92280.1 - 0.079 12.1 0.0 0.52 9.5 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 KII92280.1 - 0.084 13.3 0.0 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KII92280.1 - 0.11 12.5 0.1 14 5.6 0.0 2.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.11 KII92280.1 - 0.18 11.6 0.0 0.54 10.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arrestin_C PF02752.22 KII92281.1 - 0.0079 16.7 0.0 1.5 9.2 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Peptidase_C15 PF01470.17 KII92282.1 - 1e-06 29.1 0.1 0.024 14.8 0.0 3.4 4 0 0 4 4 4 2 Pyroglutamyl peptidase APS_kinase PF01583.20 KII92283.1 - 6.3e-72 240.6 0.0 7.4e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KII92283.1 - 5e-05 23.9 0.0 7.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII92283.1 - 0.00075 19.7 0.0 0.0013 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KII92283.1 - 0.0083 15.6 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KII92283.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.12 KII92283.1 - 0.17 11.7 0.1 0.4 10.5 0.1 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 KII92283.1 - 0.18 12.3 0.0 0.26 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.25 KII92285.1 - 1.1e-62 211.8 0.0 1.4e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92285.1 - 3.4e-47 160.9 0.0 4.4e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92285.1 - 1.9e-07 30.2 0.0 3.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII92285.1 - 0.00011 22.3 0.0 0.19 11.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KII92285.1 - 0.00038 19.9 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KII92285.1 - 0.033 13.1 0.0 0.096 11.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 KII92285.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII92285.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Hexapep PF00132.24 KII92286.1 - 2.8e-09 36.3 2.1 0.0046 16.6 4.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KII92286.1 - 1.8e-08 34.9 0.0 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KII92286.1 - 3.5e-08 33.3 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KII92286.1 - 0.00054 18.2 0.4 0.00083 17.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NOA36 PF06524.12 KII92286.1 - 4.6 6.5 12.9 8 5.7 12.9 1.4 1 0 0 1 1 1 0 NOA36 protein Hexapep_2 PF14602.6 KII92286.1 - 7.6 6.4 9.4 0.86 9.4 3.4 2.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4502 PF14950.6 KII92287.1 - 5.8e-07 29.3 0.0 9.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) DUF3232 PF11554.8 KII92288.1 - 0.13 12.6 4.3 2.8 8.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3232) eIF-3c_N PF05470.12 KII92289.1 - 9.6e-184 612.0 25.8 9.6e-184 612.0 25.8 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KII92289.1 - 3.1e-14 53.4 0.1 2.3e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF1642 PF07852.11 KII92289.1 - 0.061 13.9 3.6 0.17 12.5 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) T7SS_ESX_EspC PF10824.8 KII92289.1 - 0.18 12.3 3.1 11 6.6 0.1 3.7 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm CBP4 PF07960.11 KII92289.1 - 7 6.5 9.3 0.39 10.6 2.6 2.4 2 0 0 2 2 2 0 CBP4 Pro_racemase PF05544.11 KII92293.1 - 1.2e-45 156.0 0.0 2.2e-45 155.1 0.0 1.4 1 1 0 1 1 1 1 Proline racemase TPR_10 PF13374.6 KII92293.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PhzC-PhzF PF02567.16 KII92293.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein CAP_GLY PF01302.25 KII92295.1 - 4.2e-19 68.3 1.8 7e-19 67.6 1.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KII92295.1 - 7.3e-06 25.7 14.4 0.0016 18.3 5.2 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle FlgN PF05130.12 KII92295.1 - 0.00051 20.6 8.7 0.00051 20.6 8.7 6.1 2 1 4 6 6 6 1 FlgN protein PspA_IM30 PF04012.12 KII92295.1 - 0.004 16.8 9.7 0.004 16.8 9.7 6.2 2 2 3 5 5 5 2 PspA/IM30 family DUF4600 PF15372.6 KII92295.1 - 0.0043 17.5 6.2 0.0043 17.5 6.2 6.0 5 1 0 6 6 6 2 Domain of unknown function (DUF4600) CSF-1 PF05337.11 KII92295.1 - 0.059 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) zf-CCHC_4 PF14392.6 KII92295.1 - 0.13 12.0 5.5 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Fez1 PF06818.15 KII92295.1 - 1.9 8.9 90.1 0.21 12.0 8.1 6.0 1 1 5 6 6 6 0 Fez1 Plavaka PF18759.1 KII92299.1 - 5e-25 88.4 0.1 6.4e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase Tet_JBP PF12851.7 KII92302.1 - 0.00027 20.4 0.0 0.00061 19.2 0.0 1.6 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF3966 PF13110.6 KII92303.1 - 0.025 14.5 0.5 0.048 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) YdjO PF14169.6 KII92304.1 - 0.094 12.5 3.0 0.3 10.8 0.3 2.9 3 0 0 3 3 3 0 Cold-inducible protein YdjO PhnA_Zn_Ribbon PF08274.12 KII92304.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PIF1 PF05970.14 KII92305.1 - 2.7e-13 49.8 0.0 3.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KII92305.1 - 1.5e-10 41.1 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII92305.1 - 1.9e-08 34.7 0.0 3.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KII92305.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KII92305.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 KII92305.1 - 0.052 12.7 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KII92305.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_C13 PF01650.18 KII92307.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase C13 family E7R PF17467.2 KII92307.1 - 0.16 12.2 0.3 0.33 11.1 0.3 1.5 1 0 0 1 1 1 0 Viral Protein E7 Helitron_like_N PF14214.6 KII92308.1 - 2.5e-24 86.6 0.0 3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus GAS PF13851.6 KII92310.1 - 0.00028 20.3 3.4 0.00046 19.6 3.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FPP PF05911.11 KII92310.1 - 0.00032 19.1 1.1 0.00043 18.6 1.1 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil CENP-H PF05837.12 KII92310.1 - 0.0041 17.5 8.6 0.22 11.9 3.1 2.5 1 1 1 2 2 2 2 Centromere protein H (CENP-H) ZapB PF06005.12 KII92310.1 - 0.0082 16.6 3.7 2.3 8.7 2.0 2.4 2 0 0 2 2 2 2 Cell division protein ZapB ATG16 PF08614.11 KII92310.1 - 0.021 15.1 10.7 0.04 14.2 10.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 KII92310.1 - 0.047 11.8 5.7 0.074 11.2 5.7 1.2 1 0 0 1 1 1 0 HOOK protein HalX PF08663.10 KII92310.1 - 0.13 12.6 7.3 2.4 8.5 2.6 3.0 2 0 0 2 2 2 0 HalX domain YabA PF06156.13 KII92310.1 - 0.14 12.8 2.4 7.3 7.3 0.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA AAA_13 PF13166.6 KII92310.1 - 0.19 10.3 1.2 0.27 9.9 1.2 1.1 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 KII92310.1 - 0.44 10.6 3.0 0.82 9.7 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 KII92310.1 - 0.47 10.5 10.7 1.2 9.2 10.7 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KII92310.1 - 0.58 10.2 12.6 3.2 7.8 2.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 KII92310.1 - 1.4 9.1 9.0 3.6 7.8 3.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 vATP-synt_E PF01991.18 KII92310.1 - 2.9 7.2 6.3 4.4 6.7 2.6 2.1 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Syntaxin_2 PF14523.6 KII92311.1 - 0.056 13.8 0.6 0.056 13.8 0.6 3.0 3 0 0 3 3 3 0 Syntaxin-like protein Lzipper-MIP1 PF14389.6 KII92311.1 - 0.69 10.3 10.3 1.3 9.4 0.5 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_Xtn PF12848.7 KII92311.1 - 1.4 9.0 6.9 7.8 6.6 0.0 3.5 4 0 0 4 4 4 0 ABC transporter Cnn_1N PF07989.11 KII92313.1 - 0.002 18.2 1.6 0.002 18.2 1.6 2.3 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 DUF3584 PF12128.8 KII92313.1 - 0.022 12.3 14.6 0.03 11.8 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nsp1_C PF05064.13 KII92313.1 - 0.023 14.5 2.4 0.1 12.4 0.3 2.6 1 1 2 3 3 3 0 Nsp1-like C-terminal region SlyX PF04102.12 KII92313.1 - 0.036 14.7 17.5 0.94 10.1 0.1 5.4 3 2 2 5 5 5 0 SlyX AAA-ATPase_like PF09820.9 KII92313.1 - 0.084 12.3 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Predicted AAA-ATPase GIT_CC PF16559.5 KII92313.1 - 0.093 12.6 2.4 0.1 12.5 0.4 2.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Vps5 PF09325.10 KII92313.1 - 0.094 12.2 4.9 0.071 12.6 0.9 2.2 2 1 0 2 2 2 0 Vps5 C terminal like BLOC1_2 PF10046.9 KII92313.1 - 0.15 12.4 9.6 0.064 13.6 2.8 3.0 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2937 PF11157.8 KII92313.1 - 0.17 11.6 2.3 0.29 10.8 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF5082 PF16888.5 KII92313.1 - 0.18 12.1 7.7 5.9 7.2 1.6 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMCO5 PF14992.6 KII92313.1 - 0.8 9.2 8.0 0.86 9.1 1.7 2.1 1 1 1 2 2 2 0 TMCO5 family Syntaxin-6_N PF09177.11 KII92313.1 - 0.85 10.2 11.8 13 6.4 0.3 3.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 KII92313.1 - 1 9.8 5.9 0.3 11.5 0.8 2.5 2 0 0 2 2 2 0 Syntaxin-like protein JIP_LZII PF16471.5 KII92313.1 - 1 9.5 9.1 1.1 9.5 1.5 3.6 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II FAM76 PF16046.5 KII92313.1 - 1.4 8.2 6.9 0.52 9.6 0.2 2.1 1 1 1 2 2 2 0 FAM76 protein Fib_alpha PF08702.10 KII92313.1 - 1.4 9.0 9.1 1.2 9.3 2.4 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4337 PF14235.6 KII92313.1 - 2 8.5 6.9 1.7 8.7 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Spc7 PF08317.11 KII92313.1 - 2.3 7.0 16.3 0.37 9.6 6.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 KII92313.1 - 3.4 8.1 12.1 6.8 7.1 0.9 4.1 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PIN_8 PF18476.1 KII92313.1 - 4.4 7.1 8.3 1 9.2 2.5 2.2 1 1 1 2 2 2 0 PIN like domain DivIC PF04977.15 KII92313.1 - 6.4 6.6 9.5 3.6 7.4 0.1 3.5 2 1 1 3 3 3 0 Septum formation initiator SAP PF02037.27 KII92314.1 - 0.18 11.6 0.4 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 SAP domain Retrotran_gag_2 PF14223.6 KII92318.1 - 5.4e-06 26.1 0.0 8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Nrap_D6 PF17407.2 KII92318.1 - 0.063 13.5 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 Nrap protein domain 6 Retrotran_gag_2 PF14223.6 KII92319.1 - 5.7e-08 32.5 0.0 6e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KII92320.1 - 7.9e-07 28.8 0.0 7.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KII92321.1 - 1.2e-06 28.3 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type tRNA-synt_2c PF01411.19 KII92325.1 - 1.1e-215 717.4 0.0 1.5e-215 716.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KII92325.1 - 1.2e-17 63.7 0.4 2.8e-17 62.5 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KII92325.1 - 1e-12 48.6 1.4 1e-12 48.6 1.4 2.0 2 0 0 2 2 2 1 DHHA1 domain TadZ_N PF16968.5 KII92327.1 - 0.015 15.0 0.1 0.037 13.7 0.1 1.7 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Zn_clus PF00172.18 KII92328.1 - 1.5e-07 31.5 29.8 0.00052 20.1 15.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.21 KII92329.1 - 1.2e-23 84.1 0.0 2.3e-22 79.9 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KII92329.1 - 0.0027 17.7 0.1 2.3 8.1 0.0 2.7 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF2267 PF10025.9 KII92329.1 - 0.089 13.1 0.0 28 5.0 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) FliG_N PF14842.6 KII92329.1 - 0.1 13.2 0.0 22 5.6 0.0 2.8 3 0 0 3 3 3 0 FliG N-terminal domain SAM_decarbox PF01536.16 KII92330.1 - 5e-118 394.2 0.0 3.2e-117 391.5 0.0 1.9 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1279 PF06916.13 KII92331.1 - 7.3e-18 64.9 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RPEL PF02755.15 KII92332.1 - 9.1e-19 66.5 7.6 5.7e-10 38.6 1.5 2.7 2 1 0 2 2 2 2 RPEL repeat Sigma70_r3 PF04539.16 KII92332.1 - 0.0057 16.7 4.4 0.77 9.9 0.5 2.1 1 1 1 2 2 2 2 Sigma-70 region 3 Ricin_B_lectin PF00652.22 KII92333.1 - 2.1e-19 70.0 13.8 1.1e-12 48.4 7.8 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KII92333.1 - 5.5e-16 59.1 22.7 9.1e-12 45.6 6.1 3.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like LIFR_N PF18207.1 KII92333.1 - 0.98 9.8 3.7 41 4.6 0.1 3.4 3 0 0 3 3 3 0 Leukemia inhibitory factor receptor N-terminal domain Crisp PF08562.10 KII92333.1 - 1.6 9.4 5.3 0.53 10.9 1.2 2.3 2 0 0 2 2 2 0 Crisp Rax2 PF12768.7 KII92335.1 - 7.3e-47 159.6 14.2 1.6e-42 145.4 0.6 5.8 6 0 0 6 6 6 3 Cortical protein marker for cell polarity SH3_1 PF00018.28 KII92335.1 - 2.5e-09 36.6 0.0 5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KII92335.1 - 2.6e-07 30.4 0.4 5.4e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.25 KII92335.1 - 0.0047 16.5 3.6 3 7.5 0.1 5.7 6 0 0 6 6 6 1 Kelch motif DUF2625 PF10946.8 KII92335.1 - 0.0088 15.1 2.3 0.019 14.0 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF2625 DUF938 PF06080.12 KII92335.1 - 0.02 14.6 0.2 0.088 12.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF938) Kelch_6 PF13964.6 KII92335.1 - 2.6 8.5 15.5 48 4.5 0.1 7.1 8 0 0 8 8 8 0 Kelch motif zf-C2H2_2 PF12756.7 KII92336.1 - 5.1e-37 126.3 11.9 1.2e-31 109.0 0.1 3.1 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KII92336.1 - 6.4e-10 39.1 2.0 2.5e-09 37.2 2.0 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII92336.1 - 1.5e-08 34.7 2.0 1.5e-08 34.7 2.0 4.0 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KII92336.1 - 1.7e-08 34.6 15.8 0.018 15.8 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KII92336.1 - 2.2e-05 24.6 22.9 0.06 13.8 1.0 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type ARS2 PF04959.13 KII92336.1 - 0.011 16.1 0.4 0.037 14.4 0.0 2.0 2 0 0 2 2 2 0 Arsenite-resistance protein 2 CNDH2_C PF16858.5 KII92336.1 - 0.03 14.2 5.0 0.25 11.2 0.5 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Zf_RING PF16744.5 KII92336.1 - 0.038 14.1 1.8 0.76 9.9 0.0 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-DBF PF07535.12 KII92336.1 - 0.039 14.1 2.1 0.039 14.1 2.1 3.8 4 0 0 4 4 4 0 DBF zinc finger zf-C2H2_3rep PF18868.1 KII92336.1 - 0.78 10.4 3.8 20 5.8 0.5 3.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DNA_pol_phi PF04931.13 KII92336.1 - 6.2 4.8 14.2 10 4.1 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi PP2C PF00481.21 KII92337.1 - 2.5e-29 102.7 0.0 1.8e-27 96.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KII92337.1 - 0.01 15.8 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) FANCI_S1-cap PF14674.6 KII92337.1 - 0.042 13.9 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 cap Tho1_MOS11_C PF18592.1 KII92339.1 - 1.8e-05 24.4 3.5 0.13 12.1 0.3 3.2 3 0 0 3 3 3 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 KII92339.1 - 3.6e-05 23.4 1.7 3.6e-05 23.4 1.7 2.1 2 0 0 2 2 2 1 HeH/LEM domain Rho_N PF07498.12 KII92339.1 - 0.0057 16.6 0.5 0.01 15.7 0.5 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 KII92339.1 - 0.049 13.4 0.8 0.48 10.2 0.8 2.3 1 1 0 1 1 1 0 SAP domain Nucleo_P87 PF07267.11 KII92339.1 - 0.66 8.8 4.9 0.88 8.3 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SRP-alpha_N PF04086.13 KII92339.1 - 2.5 7.9 6.5 3.1 7.6 6.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC27 PF09507.10 KII92339.1 - 4.1 6.7 19.2 3.3 7.0 18.1 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 CBFB_NFYA PF02045.15 KII92340.1 - 4.7e-28 97.6 7.2 9.4e-28 96.6 7.2 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_S13 PF00416.22 KII92342.1 - 1.9e-55 186.7 2.4 2.2e-55 186.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KII92342.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 KII92342.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CH PF00307.31 KII92342.1 - 0.097 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Calponin homology (CH) domain Dfp1_Him1_M PF08630.10 KII92343.1 - 6.5e-35 120.1 0.2 2.1e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KII92343.1 - 8.5e-20 70.6 0.5 1.6e-19 69.7 0.5 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KII92343.1 - 0.0024 18.2 0.0 0.0049 17.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KII92343.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HA2 PF04408.23 KII92343.1 - 5.6 7.3 5.6 6.9 7.0 0.7 2.7 2 0 0 2 2 2 0 Helicase associated domain (HA2) GCP_C_terminal PF04130.13 KII92345.1 - 5.8e-61 206.6 0.2 4e-60 203.9 0.0 2.3 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KII92345.1 - 3e-07 30.4 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FAD_binding_3 PF01494.19 KII92346.1 - 3e-72 243.8 0.1 4.2e-72 243.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII92346.1 - 1.4e-06 27.7 0.2 0.0053 16.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII92346.1 - 5.5e-05 23.6 0.1 0.17 12.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII92346.1 - 0.00015 21.5 3.3 0.0054 16.4 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII92346.1 - 0.00024 21.2 0.0 0.00077 19.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII92346.1 - 0.0012 18.0 1.3 0.0097 15.0 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KII92346.1 - 0.0014 17.4 0.0 0.0078 15.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KII92346.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KII92346.1 - 0.0099 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 KII92346.1 - 0.1 12.0 0.2 1 8.8 0.0 2.6 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus LEA_6 PF10714.9 KII92346.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 AAA_16 PF13191.6 KII92347.1 - 3.7e-09 37.2 0.0 4.7e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KII92347.1 - 1.8e-08 34.7 0.0 3.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KII92347.1 - 1.8e-06 28.4 0.0 3.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KII92347.1 - 0.014 14.4 0.1 0.75 8.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KII92347.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain cobW PF02492.19 KII92347.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 KII92347.1 - 0.082 12.3 0.0 0.43 9.9 0.0 1.9 1 1 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 KII92347.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TP6A_N PF04406.14 KII92348.1 - 6.2e-18 64.5 0.2 1.1e-17 63.7 0.2 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Mito_carr PF00153.27 KII92349.1 - 4.3e-60 199.7 0.9 1.1e-24 86.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII92349.1 - 0.0034 16.6 0.6 2.2 7.4 0.0 3.0 1 1 2 3 3 3 2 Gammaproteobacterial serine protease CE2_N PF17996.1 KII92350.1 - 0.0055 16.7 0.0 0.51 10.3 0.0 3.1 3 0 0 3 3 3 1 Carbohydrate esterase 2 N-terminal CemA PF03040.14 KII92352.1 - 0.0062 16.5 0.5 0.009 16.0 0.5 1.1 1 0 0 1 1 1 1 CemA family Myosin_N PF02736.19 KII92352.1 - 0.048 13.5 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ALS2CR11 PF15729.5 KII92352.1 - 0.47 9.5 4.1 0.64 9.1 4.1 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 ARL6IP6 PF15062.6 KII92352.1 - 0.64 10.2 2.9 1.3 9.2 2.9 1.5 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix CE2_N PF17996.1 KII92353.1 - 0.002 18.1 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Amnionless PF14828.6 KII92353.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless RhoGAP PF00620.27 KII92354.1 - 2.8e-30 105.2 0.0 6.1e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_63 PF03200.16 KII92355.1 - 5.3e-07 28.8 7.0 2.4e-05 23.3 0.6 3.8 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_28 PF00295.17 KII92356.1 - 7.5e-61 206.0 16.8 9.2e-61 205.7 16.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PH_10 PF15411.6 KII92357.1 - 2.5e-38 131.1 0.1 8e-38 129.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 KII92357.1 - 2e-33 116.2 1.7 3.2e-33 115.5 1.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KII92357.1 - 3.9e-16 58.8 0.0 7.8e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KII92357.1 - 3.5e-14 52.8 0.0 7.9e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin She9_MDM33 PF05546.11 KII92357.1 - 0.027 14.3 0.3 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family PH PF00169.29 KII92357.1 - 0.087 13.3 0.2 0.24 11.9 0.0 1.8 2 0 0 2 2 2 0 PH domain CnrY PF17524.2 KII92358.1 - 0.19 12.0 1.7 0.19 11.9 1.2 1.4 1 1 0 1 1 1 0 Anti-sigma factor CnrY BRCT_2 PF16589.5 KII92360.1 - 0.031 14.7 0.1 0.089 13.2 0.0 1.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KII92360.1 - 0.12 13.0 8.2 20 5.8 0.7 3.5 2 1 1 3 3 3 0 Rap1, DNA-binding HK PF02110.15 KII92361.1 - 2.6e-71 239.9 0.1 1.5e-69 234.1 0.1 2.1 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KII92361.1 - 9.6e-55 184.7 0.0 2.2e-54 183.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 KII92361.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M19 PF01244.21 KII92361.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) PhyH PF05721.13 KII92362.1 - 5.8e-48 163.9 0.0 6.8e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF747 PF05346.11 KII92363.1 - 2.1e-112 375.8 7.0 2.5e-112 375.5 7.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family SUR7 PF06687.12 KII92365.1 - 1.4e-11 44.5 11.2 6.8e-10 38.9 11.2 2.0 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KII92365.1 - 0.00031 20.3 1.2 0.0052 16.3 0.4 2.1 2 0 0 2 2 2 2 Clc-like GFO_IDH_MocA PF01408.22 KII92367.1 - 7.8e-19 68.7 0.0 1.7e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KII92367.1 - 0.0027 18.3 0.1 0.033 14.8 0.0 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 KII92367.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RrnaAD PF00398.20 KII92368.1 - 2.8e-21 75.8 0.0 4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Mcl1_mid PF12341.8 KII92369.1 - 1.9e-83 280.3 0.0 9.5e-83 278.0 0.0 2.2 4 0 0 4 4 4 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KII92369.1 - 1.5e-14 54.1 12.6 2.4e-05 25.0 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII92369.1 - 2.5e-08 34.1 0.2 0.039 14.3 0.0 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ins134_P3_kin PF05770.11 KII92371.1 - 0.036 13.6 0.1 0.048 13.2 0.1 1.0 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain ASL_C2 PF14698.6 KII92371.1 - 0.084 13.6 0.9 0.15 12.8 0.8 1.5 1 1 0 1 1 1 0 Argininosuccinate lyase C-terminal CPSF73-100_C PF11718.8 KII92372.1 - 2.3e-66 223.4 0.2 3.3e-66 222.9 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KII92372.1 - 1.4e-29 102.6 0.0 3.3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KII92372.1 - 1.1e-18 67.4 0.0 2.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KII92372.1 - 2.1e-18 67.1 0.5 9.2e-18 65.0 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KII92372.1 - 2.4e-17 62.6 0.2 7.5e-17 61.0 0.2 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KII92372.1 - 9.1e-08 31.8 1.0 3.7e-07 29.9 0.4 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KII92372.1 - 1.2e-06 28.5 0.0 9.9e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Macoilin PF09726.9 KII92373.1 - 3.2 6.2 8.4 3.8 6.0 8.4 1.1 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_76 PF03663.14 KII92374.1 - 1.6e-38 133.2 22.5 2e-38 132.9 22.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 KII92374.1 - 0.014 14.9 1.2 0.47 9.9 0.1 2.8 2 1 1 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Sec7 PF01369.20 KII92375.1 - 8.6e-28 97.3 0.2 1.8e-27 96.2 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KII92375.1 - 1.7e-26 92.9 0.0 3.7e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KII92375.1 - 0.0027 18.2 0.0 0.0076 16.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Lzipper-MIP1 PF14389.6 KII92375.1 - 0.021 15.1 2.6 0.077 13.3 2.6 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 KII92375.1 - 0.49 10.6 2.3 1 9.6 2.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GATA PF00320.27 KII92376.1 - 1.5e-18 66.1 2.8 2.9e-18 65.2 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KII92376.1 - 1.9e-11 43.6 1.0 1.9e-11 43.6 1.0 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Peptidase_A22B PF04258.13 KII92377.1 - 1.2e-70 238.3 2.3 1.9e-70 237.6 2.3 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KII92377.1 - 1.4e-06 28.0 4.4 1.4e-06 28.0 4.4 1.8 1 1 1 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease DUF502 PF04367.13 KII92377.1 - 0.071 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF502) Cellulase PF00150.18 KII92378.1 - 9.8e-29 100.7 3.6 1.3e-28 100.2 3.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KII92378.1 - 0.0073 15.5 0.0 0.021 13.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain G_glu_transpept PF01019.21 KII92379.1 - 2.7e-167 557.6 0.0 3.1e-167 557.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Keratin PF02422.16 KII92381.1 - 0.1 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Keratin TIP49 PF06068.13 KII92384.1 - 1.5e-158 527.6 0.0 1.9e-158 527.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KII92384.1 - 1.4e-19 70.0 0.0 2.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KII92384.1 - 6.9e-10 39.5 0.1 1.9e-06 28.3 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KII92384.1 - 1.5e-08 34.6 0.0 7.2e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KII92384.1 - 8.4e-07 29.3 0.1 0.022 15.0 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KII92384.1 - 8.7e-06 26.2 0.0 6.8e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KII92384.1 - 1.2e-05 25.3 0.1 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KII92384.1 - 0.0012 19.1 0.0 0.0035 17.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII92384.1 - 0.0019 17.8 0.1 0.0038 16.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII92384.1 - 0.003 17.9 1.6 0.017 15.5 0.5 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KII92384.1 - 0.036 13.4 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KII92384.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KII92384.1 - 0.04 13.6 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 KII92384.1 - 0.044 13.5 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KII92384.1 - 0.062 12.8 0.1 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KII92384.1 - 0.094 12.0 0.2 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KII92384.1 - 0.1 13.1 0.1 0.51 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KII92384.1 - 0.12 12.3 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KII92384.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KII92384.1 - 1.3 8.4 4.1 1.3 8.5 0.1 2.6 4 0 0 4 4 4 0 PhoH-like protein HYLS1_C PF15311.6 KII92385.1 - 0.032 15.0 0.0 0.13 13.0 0.0 2.1 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Oxidored_q6 PF01058.22 KII92386.1 - 2.2e-22 79.3 0.1 3.4e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit F-box PF00646.33 KII92387.1 - 2.9e-08 33.4 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII92387.1 - 4.8e-07 29.6 0.1 7.7e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like Amelotin PF15757.5 KII92388.1 - 0.00094 18.8 0.3 0.39 10.3 0.1 2.1 1 1 1 2 2 2 2 Amelotin LcrG PF07216.12 KII92388.1 - 0.083 12.8 2.8 1.8 8.6 0.3 2.3 1 1 0 2 2 2 0 LcrG protein Pkinase PF00069.25 KII92389.1 - 9.5e-51 172.7 0.0 3.8e-36 124.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII92389.1 - 1e-20 74.1 0.0 7.2e-20 71.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII92389.1 - 0.00025 21.1 0.1 0.00047 20.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII92389.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII92389.1 - 0.048 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KII92389.1 - 0.051 12.9 0.1 0.084 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KII92389.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain HhH-GPD PF00730.25 KII92390.1 - 7.3e-16 58.6 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Inhibitor_I9 PF05922.16 KII92391.1 - 3.1e-06 27.8 0.0 6.4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 KII92391.1 - 0.05 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain AIM5 PF17050.5 KII92392.1 - 2.8e-05 24.8 0.0 4.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Ice_nucleation PF00818.17 KII92392.1 - 1.7 8.9 0.1 1.7 8.9 0.1 2.7 3 0 0 3 3 3 0 Ice nucleation protein repeat NUDIX PF00293.28 KII92393.1 - 1.5e-08 34.8 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KII92393.1 - 7.5e-06 25.9 0.0 2.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) AA_permease_2 PF13520.6 KII92394.1 - 2.3e-49 168.4 41.4 2.9e-49 168.1 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease O-antigen_lig PF13425.6 KII92394.1 - 7.3 5.3 8.9 1.3 7.7 2.0 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein SLAC1 PF03595.17 KII92396.1 - 3.9e-73 246.5 44.4 4.5e-73 246.3 44.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Saf_2TM PF18303.1 KII92396.1 - 0.34 10.5 9.1 0.35 10.5 0.1 3.6 4 0 0 4 4 4 0 SAVED-fused 2TM effector domain adh_short PF00106.25 KII92397.1 - 6.5e-31 107.3 0.0 5.1e-29 101.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII92397.1 - 6.1e-21 75.1 0.0 6.2e-19 68.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92397.1 - 1.4e-09 38.1 0.1 2e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII92397.1 - 3.5e-05 23.4 0.2 6.7e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KII92397.1 - 0.00014 22.1 0.1 0.00029 21.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KII92397.1 - 0.00031 20.3 0.1 0.00045 19.7 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KII92397.1 - 0.044 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TIR-like PF10137.9 KII92397.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NAD_binding_2 PF03446.15 KII92397.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase baeRF_family3 PF18845.1 KII92397.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 RRM_1 PF00076.22 KII92399.1 - 1.1e-10 41.1 0.1 0.00064 19.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII92399.1 - 0.0025 17.9 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Rpn9_C PF18261.1 KII92399.1 - 2.3 7.9 3.9 1.1 9.0 1.4 1.7 2 0 0 2 2 2 0 Rpn9 C-terminal helix PI3_PI4_kinase PF00454.27 KII92400.1 - 5.5e-34 118.1 0.0 8.2e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Mnd1 PF03962.15 KII92401.1 - 2.3e-30 104.6 0.3 4.2e-30 103.8 0.3 1.4 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KII92401.1 - 1.6e-08 34.5 0.0 4.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain MscS_porin PF12795.7 KII92401.1 - 0.0015 18.1 3.2 0.0023 17.5 3.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain CC2-LZ PF16516.5 KII92401.1 - 0.06 13.7 0.9 0.13 12.6 0.9 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FUR PF01475.19 KII92401.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family SMK-1 PF04802.15 KII92401.1 - 0.072 12.9 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Component of IIS longevity pathway SMK-1 Phage_lysozyme2 PF18013.1 KII92401.1 - 0.082 12.9 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Phage tail lysozyme DNA_Packaging PF11053.8 KII92401.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Tannase PF07519.11 KII92403.1 - 6.2e-110 368.3 0.4 7.5e-110 368.0 0.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KII92403.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-MYND PF01753.18 KII92404.1 - 0.014 15.4 9.1 0.033 14.3 9.1 1.6 1 0 0 1 1 1 0 MYND finger RNA_pol_Rpb5_C PF01191.19 KII92404.1 - 0.14 12.0 0.0 0.46 10.4 0.0 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Rhodanese_C PF12368.8 KII92404.1 - 0.24 11.8 4.0 0.45 10.9 4.0 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Tnp_zf-ribbon_2 PF13842.6 KII92404.1 - 2.6 8.9 7.1 5.5 7.9 7.1 1.6 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Fungal_trans PF04082.18 KII92405.1 - 4.9e-08 32.3 0.0 8.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92405.1 - 1.4e-07 31.5 12.4 2.5e-07 30.7 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSSC4 PF15264.6 KII92405.1 - 0.097 12.9 0.3 0.24 11.7 0.3 1.6 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 W2 PF02020.18 KII92406.1 - 2e-19 69.5 0.3 6.3e-19 67.9 0.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Choline_transpo PF04515.12 KII92408.1 - 6.4e-78 262.2 10.2 6.4e-78 262.2 10.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter PP2C PF00481.21 KII92409.1 - 1.5e-65 221.4 0.1 2.3e-51 174.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KII92409.1 - 0.034 14.1 0.3 0.13 12.2 0.3 1.9 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Amastin PF07344.11 KII92410.1 - 0.00034 20.5 3.8 0.00068 19.5 1.3 2.3 2 1 0 2 2 2 1 Amastin surface glycoprotein DUF998 PF06197.13 KII92410.1 - 0.00042 20.0 7.4 0.00042 20.0 7.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF998) PhnH PF05845.12 KII92410.1 - 0.076 12.8 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnH) Claudin_3 PF06653.11 KII92410.1 - 0.12 12.3 5.3 0.48 10.4 1.7 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like DUF2157 PF09925.9 KII92410.1 - 0.29 10.9 4.5 0.075 12.8 1.5 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3382 PF11862.8 KII92410.1 - 0.35 11.2 4.1 0.12 12.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) MNHE PF01899.16 KII92410.1 - 0.43 10.3 4.6 0.27 11.0 2.6 1.6 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit CcmD PF04995.14 KII92410.1 - 0.44 10.7 6.3 7.9 6.7 0.3 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SUR7 PF06687.12 KII92410.1 - 7.8 6.1 8.8 0.53 9.9 3.1 2.0 1 1 1 2 2 2 0 SUR7/PalI family DUF2768 PF10966.8 KII92410.1 - 9.8 6.7 10.6 1.2 9.6 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Acyltransferase PF01553.21 KII92411.1 - 3.6e-13 49.3 0.0 6.4e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Aconitase_C PF00694.19 KII92411.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 Aconitase C-terminal domain NUC173 PF08161.12 KII92412.1 - 5.5e-57 192.7 0.0 4.6e-55 186.5 0.0 2.6 2 0 0 2 2 2 2 NUC173 domain MMS19_C PF12460.8 KII92412.1 - 0.011 14.9 0.4 0.011 14.9 0.4 4.4 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 KII92412.1 - 0.029 14.6 1.0 24 5.6 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat PAC2 PF09754.9 KII92413.1 - 5.5e-24 85.4 0.0 8.9e-24 84.7 0.0 1.3 1 1 0 1 1 1 1 PAC2 family FAD_binding_3 PF01494.19 KII92414.1 - 9e-15 54.8 0.0 2.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain ETF PF01012.21 KII92415.1 - 8.2e-35 120.3 0.7 1.3e-34 119.6 0.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KII92415.1 - 2.7e-32 110.6 0.7 5.3e-32 109.7 0.7 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA_12 PF13087.6 KII92416.1 - 2.2e-34 118.8 0.0 4e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KII92416.1 - 1.1e-21 77.8 5.5 5e-12 46.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 KII92416.1 - 1.5e-10 41.5 0.1 3e-07 30.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KII92416.1 - 4.3e-09 36.4 0.1 4.5e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 KII92416.1 - 0.0048 16.2 0.0 0.091 12.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Mac PF12464.8 KII92416.1 - 0.029 14.6 2.3 0.38 11.0 0.4 3.1 2 0 0 2 2 2 0 Maltose acetyltransferase UvsW PF11637.8 KII92416.1 - 0.15 12.2 1.0 0.38 10.9 0.2 2.1 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW TFIID_20kDa PF03847.13 KII92417.1 - 3.2e-28 98.0 0.5 5.4e-28 97.3 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KII92417.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII92417.1 - 0.04 14.3 0.8 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Glyoxal_oxid_N PF07250.11 KII92418.1 - 1.8e-30 105.9 0.6 1.7e-27 96.2 0.4 3.6 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KII92418.1 - 7.9e-23 80.6 0.0 1.6e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KII92418.1 - 0.0037 17.2 0.9 3.2 7.8 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Git3 PF11710.8 KII92419.1 - 3.5e-08 33.5 3.6 6.6e-08 32.6 3.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KII92419.1 - 0.0016 17.8 0.5 0.0043 16.4 0.5 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KII92419.1 - 0.016 15.2 1.0 0.047 13.8 1.0 1.8 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term HSP20 PF00011.21 KII92423.1 - 9.9e-05 22.4 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KII92423.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 HSP20-like domain found in ArsA FAD_binding_3 PF01494.19 KII92425.1 - 1.2e-16 60.9 0.0 2e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KII92425.1 - 1.3e-07 31.3 0.2 8.9e-05 21.9 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 KII92425.1 - 8.9e-07 28.8 0.1 8.7e-05 22.3 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII92425.1 - 9.1e-07 29.0 0.2 2e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII92425.1 - 2.9e-06 26.7 0.1 8.5e-05 21.9 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KII92425.1 - 7e-06 25.4 0.0 1.5e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII92425.1 - 0.00023 20.0 0.0 0.0065 15.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KII92425.1 - 0.012 16.2 0.0 0.059 13.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII92425.1 - 0.023 14.0 0.0 0.052 12.8 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII92425.1 - 0.034 13.4 0.1 0.1 11.8 0.0 1.8 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KII92425.1 - 0.051 12.9 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KII92425.1 - 0.078 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AFG1_ATPase PF03969.16 KII92426.1 - 6.1e-60 203.0 0.0 1.2e-54 185.6 0.0 3.2 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KII92426.1 - 1.3e-09 38.7 0.2 4.2e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 KII92426.1 - 0.00045 20.3 0.0 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 KII92426.1 - 0.00046 20.5 0.0 0.0019 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KII92426.1 - 0.004 16.9 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 KII92426.1 - 0.0093 16.0 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KII92426.1 - 0.015 15.0 0.0 4.2 7.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 KII92426.1 - 0.018 15.4 0.0 0.095 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KII92426.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KII92426.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 KII92426.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 KII92427.1 - 7.9e-19 68.0 0.0 1.6e-18 67.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92427.1 - 1.1e-12 47.8 0.0 1.2e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KII92427.1 - 0.0037 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Ten_N PF06484.12 KII92427.1 - 0.01 15.7 5.9 0.017 15.0 5.9 1.3 1 0 0 1 1 1 0 Teneurin Intracellular Region CxC6 PF18721.1 KII92428.1 - 6.5e-25 87.2 4.7 2.4e-24 85.4 4.7 2.0 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 KII92428.1 - 2e-24 85.9 1.0 2e-24 85.9 1.0 2.2 3 0 0 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases RTC4 PF14474.6 KII92429.1 - 5.6e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Nkap_C PF06047.11 KII92430.1 - 3.9e-42 142.5 3.9 3.9e-42 142.5 3.9 2.4 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain SAPS PF04499.15 KII92430.1 - 4.5 5.9 6.5 5.8 5.6 6.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 KII92430.1 - 7.9 5.6 9.8 13 4.9 9.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FKBP_C PF00254.28 KII92431.1 - 7.3e-32 109.6 0.0 8.8e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.20 KII92432.1 - 5.9e-23 80.2 9.9 6.9e-23 80.0 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 KII92432.1 - 0.029 13.9 0.4 0.029 13.9 0.4 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 CHD5 PF04420.14 KII92433.1 - 1.4e-51 174.5 1.8 1.8e-51 174.2 1.8 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF1043 PF06295.12 KII92433.1 - 0.038 14.0 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) GP57 PF17594.2 KII92433.1 - 0.055 13.2 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 BHD_2 PF10404.9 KII92433.1 - 0.18 12.7 0.4 4 8.5 0.2 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Vps8 PF12816.7 KII92434.1 - 3.3e-69 232.4 0.0 5e-67 225.2 0.0 2.5 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KII92434.1 - 0.0011 18.9 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 KII92434.1 - 0.018 15.3 0.0 5.1 7.5 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII92434.1 - 0.11 13.4 0.1 0.64 11.0 0.1 2.4 1 0 0 1 1 1 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KII92434.1 - 0.18 12.3 2.5 4.3 8.0 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF3510 PF12022.8 KII92438.1 - 1.3e-30 106.4 0.0 3.3e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KII92438.1 - 6.1e-23 81.4 0.3 1.4e-22 80.2 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 PHD PF00628.29 KII92439.1 - 7e-11 41.9 8.7 1.1e-10 41.2 8.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KII92439.1 - 0.1 12.6 1.6 0.21 11.6 1.6 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger BTV_NS2 PF04514.12 KII92439.1 - 0.24 10.2 1.2 0.38 9.5 1.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PHD_2 PF13831.6 KII92439.1 - 0.78 9.3 3.5 1.4 8.5 3.5 1.4 1 0 0 1 1 1 0 PHD-finger PALP PF00291.25 KII92440.1 - 8.2e-77 258.5 0.1 1.1e-76 258.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KII92440.1 - 3.2e-39 132.6 0.0 1.4e-24 85.6 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase NDUF_B12 PF08122.12 KII92441.1 - 2e-20 72.6 1.7 2.1e-20 72.5 1.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.9 KII92441.1 - 4.6 7.5 6.2 5.2 7.3 1.3 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Topoisom_I PF01028.20 KII92442.1 - 5.6e-99 330.1 6.1 5.6e-99 330.1 6.1 1.9 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KII92442.1 - 6.2e-97 323.3 1.0 6.2e-97 323.3 1.0 3.5 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KII92442.1 - 1.6e-34 117.6 0.2 5.7e-34 115.9 0.2 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain CTP_transf_1 PF01148.20 KII92443.1 - 6.6e-73 245.7 18.9 1e-72 245.1 18.9 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.25 KII92444.1 - 2.4e-49 165.7 1.1 3e-49 165.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.20 KII92445.1 - 4.4e-09 36.4 0.0 7.7e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII92445.1 - 0.028 15.0 0.1 0.037 14.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family C2 PF00168.30 KII92446.1 - 2.9e-13 50.0 0.0 8.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 KII92446.1 - 3.5e-07 30.8 18.9 0.18 12.7 0.0 7.8 7 1 0 7 7 7 3 WD domain, G-beta repeat NACHT PF05729.12 KII92446.1 - 6.2e-06 26.2 0.0 2.4e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KII92446.1 - 1.1e-05 25.9 0.0 9.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KII92446.1 - 0.0021 17.3 0.0 0.0061 15.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KII92446.1 - 0.017 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain EMP70 PF02990.16 KII92448.1 - 6.5e-197 655.3 0.0 1e-196 654.7 0.0 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1b PF00579.25 KII92449.1 - 1.1e-72 244.9 0.0 1.5e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KII92449.1 - 1.2e-06 28.1 0.3 3.5e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 S4 domain TGT PF01702.18 KII92450.1 - 3.4e-130 434.3 0.0 4e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.29 KII92451.1 - 7.5e-38 130.0 0.0 2.4e-37 128.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII92451.1 - 6.5e-23 81.2 0.3 2.3e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KII92451.1 - 1.1e-18 67.2 5.0 1.1e-18 67.2 5.0 2.5 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Pkinase_fungal PF17667.1 KII92452.1 - 2.1e-60 204.6 2.0 6.3e-59 199.8 2.0 2.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII92452.1 - 0.0032 16.9 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KII92452.1 - 0.0072 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KII92452.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_A_bac PF01000.26 KII92453.1 - 6.5e-29 100.6 0.0 1.2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KII92453.1 - 4.1e-19 67.8 0.0 5.9e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Methyltransf_2 PF00891.18 KII92454.1 - 8.4e-25 87.3 0.0 2.7e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_2 PF00891.18 KII92455.1 - 6.4e-24 84.4 0.0 1.1e-19 70.5 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Dimerisation PF08100.11 KII92455.1 - 0.00093 19.2 0.1 0.0034 17.4 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain DUF2868 PF11067.8 KII92455.1 - 0.034 13.7 0.1 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MTS PF05175.14 KII92455.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KII92455.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KII92455.1 - 0.096 13.4 0.0 0.22 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KII92455.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.16 KII92455.1 - 0.2 11.4 0.1 0.33 10.7 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein ADH_zinc_N PF00107.26 KII92456.1 - 7.7e-31 106.8 0.2 1.1e-30 106.3 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII92456.1 - 7e-17 62.7 0.0 1.1e-16 62.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII92456.1 - 2.3e-07 30.7 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KII92456.1 - 0.028 13.9 0.4 0.042 13.3 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KII92456.1 - 0.068 12.5 0.5 0.11 11.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF913 PF06025.12 KII92457.1 - 8.9e-102 340.8 0.0 8.9e-102 340.8 0.0 4.9 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.25 KII92457.1 - 6.1e-93 311.7 0.0 1.4e-92 310.5 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KII92457.1 - 3.8e-86 289.7 0.4 3.8e-86 289.7 0.4 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KII92457.1 - 2.5e-28 96.6 15.8 2e-11 43.0 0.5 4.1 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KII92457.1 - 1.5e-10 40.8 0.0 4.2e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain PC4 PF02229.16 KII92458.1 - 4.1e-24 84.0 0.4 4.1e-24 84.0 0.4 1.6 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) DTHCT PF08070.11 KII92458.1 - 2.1 9.1 24.2 4.6 8.0 16.2 2.5 1 1 1 2 2 2 0 DTHCT (NUC029) region Sec62 PF03839.16 KII92458.1 - 2.2 7.7 6.7 2.8 7.4 6.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Herpes_DNAp_acc PF04929.12 KII92458.1 - 2.9 6.8 9.2 3.8 6.4 9.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIF_alpha PF05793.12 KII92458.1 - 3 6.3 22.4 0.64 8.6 19.2 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 KII92458.1 - 7.5 4.7 9.9 6.9 4.8 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein ABC1 PF03109.16 KII92459.1 - 1.6e-32 112.1 0.0 2.5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KII92459.1 - 0.016 14.8 0.1 0.093 12.3 0.1 2.0 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KII92459.1 - 0.041 13.3 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain HSP9_HSP12 PF04119.12 KII92460.1 - 1.1e-23 83.4 2.1 1.5e-23 82.9 2.1 1.2 1 0 0 1 1 1 1 Heat shock protein 9/12 zf-RING_2 PF13639.6 KII92461.1 - 1.1e-11 44.8 5.1 1.7e-11 44.2 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KII92461.1 - 4.1e-07 29.6 1.7 4.1e-07 29.6 1.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KII92461.1 - 1.3e-06 28.4 1.3 2.1e-06 27.7 1.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KII92461.1 - 1.6e-06 27.8 5.0 2.8e-06 27.0 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KII92461.1 - 4.1e-05 23.3 3.5 6.5e-05 22.6 3.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KII92461.1 - 7.1e-05 23.0 6.3 0.0002 21.6 6.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KII92461.1 - 9.5e-05 22.2 2.9 0.00015 21.5 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII92461.1 - 0.00017 21.4 2.1 0.00027 20.8 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KII92461.1 - 0.0016 18.3 1.1 0.0026 17.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KII92461.1 - 0.0064 16.6 2.0 0.014 15.5 2.0 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KII92461.1 - 0.0068 16.2 6.2 0.044 13.7 6.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KII92461.1 - 0.0089 16.0 4.0 0.41 10.7 1.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 KII92461.1 - 0.026 14.7 2.7 0.046 13.8 2.7 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KII92461.1 - 0.55 10.2 4.6 4.9 7.2 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UBZ_FAAP20 PF15750.5 KII92461.1 - 0.63 10.0 2.6 10 6.2 0.7 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF2946 PF11162.8 KII92461.1 - 4.9 7.8 8.6 1.2 9.8 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) HTH_21 PF13276.6 KII92463.1 - 0.092 12.9 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain Alpha_kinase PF02816.18 KII92464.1 - 8.9e-15 55.3 0.0 1.1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_3 PF00202.21 KII92465.1 - 1.6e-112 376.2 0.0 1.9e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KII92465.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Amidohydro_1 PF01979.20 KII92466.1 - 7.9e-36 124.1 0.0 1e-35 123.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KII92466.1 - 2.2e-15 57.1 0.2 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Yippee-Mis18 PF03226.14 KII92467.1 - 2.3e-08 34.2 0.1 3.1e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RabGAP-TBC PF00566.18 KII92468.1 - 5.8e-52 176.5 0.2 1e-51 175.6 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pox_MCEL PF03291.16 KII92468.1 - 0.16 11.1 1.6 0.25 10.4 1.6 1.2 1 0 0 1 1 1 0 mRNA capping enzyme HALZ PF02183.18 KII92468.1 - 0.16 12.2 1.2 0.45 10.8 1.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper APG6_N PF17675.1 KII92468.1 - 3.2 8.3 14.2 0.041 14.4 4.6 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 KII92468.1 - 7.8 6.6 10.6 0.17 11.9 2.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cauli_VI PF01693.16 KII92469.1 - 0.02 15.2 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin ATG27 PF09451.10 KII92470.1 - 2.3e-66 224.4 0.0 3e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KII92470.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Josephin PF02099.17 KII92471.1 - 2.8e-49 167.4 0.1 5.1e-49 166.5 0.1 1.4 1 0 0 1 1 1 1 Josephin Acetyltransf_10 PF13673.7 KII92472.1 - 5.9e-10 39.2 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII92472.1 - 8.1e-10 39.0 0.0 1.7e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII92472.1 - 6.6e-08 32.8 0.0 9e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KII92472.1 - 0.0026 17.8 0.1 0.0076 16.3 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Endosulfine PF04667.17 KII92472.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 1 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region FR47 PF08445.10 KII92472.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 KII92472.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DASH_Duo1 PF08651.10 KII92473.1 - 1.9e-19 69.2 0.4 3e-19 68.6 0.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Mannosyl_trans2 PF04188.13 KII92474.1 - 3.9e-46 158.3 15.6 5.2e-46 157.9 15.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) LRR_4 PF12799.7 KII92475.1 - 0.00038 20.8 8.8 20 5.8 0.0 6.8 7 1 1 8 8 8 3 Leucine Rich repeats (2 copies) TFIIS_C PF01096.18 KII92476.1 - 2.5e-18 65.6 1.4 2.5e-18 65.6 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KII92476.1 - 6.2e-06 26.0 0.8 6.2e-06 26.0 0.8 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.12 KII92476.1 - 0.00021 21.2 12.5 0.3 11.1 5.4 3.5 2 2 1 3 3 3 2 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.6 KII92476.1 - 0.00041 20.0 5.4 1.3 8.9 0.1 3.4 3 0 0 3 3 3 2 zinc-ribbon domain DZR PF12773.7 KII92476.1 - 0.00067 19.6 7.5 0.012 15.7 0.3 2.7 2 1 0 2 2 2 1 Double zinc ribbon zf-RING_7 PF02591.15 KII92476.1 - 0.00083 19.5 7.2 0.9 9.8 0.0 3.9 4 0 0 4 4 4 1 C4-type zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KII92476.1 - 0.0047 16.9 8.1 0.012 15.6 0.6 2.7 2 1 1 3 3 3 1 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 KII92476.1 - 0.0075 15.9 3.6 0.03 14.0 0.7 2.5 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain PriA_CRR PF18319.1 KII92476.1 - 0.0092 16.0 1.3 0.05 13.6 0.2 2.6 2 1 0 2 2 2 1 PriA DNA helicase Cys-rich region (CRR) domain Zn-ribbon_8 PF09723.10 KII92476.1 - 0.026 14.7 9.9 1 9.5 0.1 3.9 3 1 1 4 4 4 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 KII92476.1 - 0.035 13.8 8.2 2 8.2 0.7 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit IBR PF01485.21 KII92476.1 - 0.061 13.6 10.6 0.12 12.6 0.3 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-UBR PF02207.20 KII92476.1 - 0.085 13.0 9.2 0.22 11.7 0.4 3.1 2 1 1 3 3 3 0 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.12 KII92476.1 - 0.093 12.3 12.3 0.12 11.9 0.8 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding PADR1 PF08063.12 KII92476.1 - 0.12 12.2 7.4 0.19 11.5 0.2 3.3 4 0 0 4 4 4 0 PADR1 (NUC008) domain Mu-like_Com PF10122.9 KII92476.1 - 0.12 11.8 3.0 7.8 6.0 0.4 2.5 2 1 0 2 2 2 0 Mu-like prophage protein Com PHD PF00628.29 KII92476.1 - 0.13 12.2 9.3 1.9 8.4 0.9 2.8 2 1 0 2 2 2 0 PHD-finger Lar_restr_allev PF14354.6 KII92476.1 - 0.13 12.6 8.1 0.97 9.9 0.9 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 KII92476.1 - 0.14 12.4 9.7 9.5 6.6 0.1 4.1 3 1 1 4 4 4 0 zinc-ribbon zinc_ribbon_10 PF10058.9 KII92476.1 - 0.15 11.8 8.3 5.3 6.8 0.4 3.9 3 1 1 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein OrfB_Zn_ribbon PF07282.11 KII92476.1 - 0.19 11.6 8.8 4 7.4 0.4 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF1451 PF07295.11 KII92476.1 - 0.29 11.2 11.3 1.9 8.5 3.6 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain Ribosomal_S27e PF01667.17 KII92476.1 - 0.31 10.8 6.7 6 6.6 0.8 2.9 3 1 0 3 3 3 0 Ribosomal protein S27 zf-C4_Topoisom PF01396.19 KII92476.1 - 0.34 10.7 7.6 1.9 8.3 0.3 3.4 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF3268 PF11672.8 KII92476.1 - 0.35 11.2 4.5 0.27 11.6 0.8 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain zf-tcix PF14952.6 KII92476.1 - 0.5 10.0 3.8 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 KII92476.1 - 0.52 9.8 12.8 1.7 8.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KII92476.1 - 1.2 9.0 10.7 1.6 8.6 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain DNA_ligase_ZBD PF03119.16 KII92476.1 - 1.4 9.0 7.7 5.6 7.1 0.3 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf_UBZ PF18439.1 KII92476.1 - 2.1 8.0 10.4 14 5.4 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger CpXC PF14353.6 KII92476.1 - 2.4 8.2 10.0 57 3.8 0.0 3.7 2 1 1 3 3 3 0 CpXC protein zinc_ribbon_5 PF13719.6 KII92476.1 - 3.2 7.6 8.0 2.3 8.1 0.9 3.4 3 1 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.9 KII92476.1 - 4.1 7.6 16.1 1.8 8.7 1.3 3.4 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_4 PF13717.6 KII92476.1 - 7.2 6.6 10.5 35 4.4 0.2 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 KII92476.1 - 8.1 7.1 8.4 23 5.6 1.0 3.0 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF563 PF04577.14 KII92478.1 - 1.9e-14 54.3 0.0 4.8e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF3421 PF11901.8 KII92479.1 - 4e-31 107.4 1.8 3e-24 85.2 0.3 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) DUF2076 PF09849.9 KII92479.1 - 0.0087 16.1 6.8 0.014 15.5 6.8 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gram_pos_anchor PF00746.21 KII92479.1 - 0.02 14.8 0.9 0.042 13.8 0.9 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ABA_WDS PF02496.16 KII92479.1 - 4 8.0 6.4 1.7 9.2 0.2 2.9 3 0 0 3 3 3 0 ABA/WDS induced protein Cellulase PF00150.18 KII92481.1 - 1.4e-28 100.1 2.1 1.9e-28 99.7 2.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KII92481.1 - 5e-13 48.7 5.5 5e-13 48.7 5.5 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KII92481.1 - 0.00013 21.2 0.0 0.00029 20.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydr_30_2 PF14587.6 KII92482.1 - 2.5e-19 70.1 4.4 5.4e-19 69.0 4.4 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_transf_49 PF13896.6 KII92483.1 - 0.17 11.2 0.0 0.42 9.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl-transferase for dystroglycan Metal_resist PF13801.6 KII92485.1 - 3.9 7.7 7.3 1 9.6 0.9 3.1 3 1 0 3 3 3 0 Heavy-metal resistance Palm_thioest PF02089.15 KII92487.1 - 6.4e-79 265.2 0.0 3.6e-77 259.5 0.0 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 KII92487.1 - 0.0073 16.0 0.0 0.051 13.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold CsbD PF05532.12 KII92488.1 - 8.9e-12 44.7 18.6 1.5e-08 34.4 4.0 2.3 1 1 1 2 2 2 2 CsbD-like SUZ PF12752.7 KII92488.1 - 4.8 8.0 5.9 1.5 9.6 3.0 1.9 2 1 0 2 2 2 0 SUZ domain Nucleos_tra2_C PF07662.13 KII92489.1 - 4.7e-67 225.8 7.6 4.7e-67 225.8 7.6 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KII92489.1 - 3e-19 69.4 6.9 3e-19 69.4 6.9 3.7 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KII92489.1 - 0.52 10.6 17.2 0.034 14.4 5.9 2.8 2 0 0 2 2 2 0 Nucleoside recognition WD40 PF00400.32 KII92490.1 - 2.9e-11 43.7 0.2 8.8e-05 23.2 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Sugar_tr PF00083.24 KII92491.1 - 2.8e-94 316.5 23.0 3.3e-94 316.3 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII92491.1 - 2.3e-17 63.0 43.5 7.5e-14 51.4 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII92492.1 - 2e-91 307.2 23.5 2.5e-91 306.8 23.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII92492.1 - 3.3e-18 65.7 45.5 6e-12 45.2 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPA_interact_C PF14768.6 KII92493.1 - 0.0073 16.8 0.3 0.011 16.3 0.3 1.2 1 0 0 1 1 1 1 Replication protein A interacting C-terminal DUF4271 PF14093.6 KII92494.1 - 0.053 13.4 3.5 0.076 12.9 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF5572 PF17733.1 KII92494.1 - 1.4 8.8 3.7 3.1 7.7 3.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5572) MPC PF03650.13 KII92496.1 - 5.8e-34 116.5 0.1 8.8e-34 116.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MPC PF03650.13 KII92497.1 - 1.9e-36 124.5 0.5 6.4e-18 64.9 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial pyruvate carriers zinc_ribbon_16 PF17034.5 KII92498.1 - 8.3e-16 58.3 8.2 3e-15 56.5 8.2 1.9 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KII92498.1 - 0.00042 19.9 5.2 0.00042 19.9 5.2 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Nudix_hydro PF18290.1 KII92498.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Nudix hydrolase domain ANAPC4_WD40 PF12894.7 KII92498.1 - 0.17 12.2 0.0 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_4 PF13717.6 KII92498.1 - 0.54 10.2 3.9 0.26 11.2 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 KII92498.1 - 0.87 10.2 5.6 7.2 7.3 0.1 3.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DASH_Dad4 PF08650.10 KII92499.1 - 1.9e-23 82.2 2.3 2.1e-23 82.0 2.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 IMPa_helical PF18642.1 KII92499.1 - 0.04 14.3 0.3 0.062 13.7 0.3 1.4 1 1 0 1 1 1 0 Immunomodulating metalloprotease helical domain Sugar_tr PF00083.24 KII92502.1 - 5.2e-85 286.0 25.3 5.9e-85 285.8 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII92502.1 - 1e-32 113.5 45.3 4.2e-25 88.4 22.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KII92502.1 - 0.00032 19.2 4.0 0.19 10.0 0.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Toxin_5 PF05294.13 KII92503.1 - 0.34 11.4 7.1 0.61 10.6 7.1 1.4 1 0 0 1 1 1 0 Scorpion short toxin Creatinase_N_2 PF16189.5 KII92504.1 - 3.8e-43 147.4 0.0 7.1e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KII92504.1 - 1.8e-42 145.5 0.0 2.4e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KII92504.1 - 1.6e-21 76.1 1.3 4e-21 74.9 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KII92504.1 - 1.5e-08 35.4 0.1 5.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain NOG1_N PF17835.1 KII92505.1 - 5.8e-50 169.4 0.5 1.3e-49 168.3 0.5 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KII92505.1 - 3.1e-28 97.5 0.7 9.5e-28 96.0 0.7 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KII92505.1 - 5.6e-27 93.3 0.0 1.2e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KII92505.1 - 3.1e-17 62.7 0.0 8.1e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII92505.1 - 9.4e-11 41.5 0.0 2.2e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KII92505.1 - 0.00093 19.1 0.1 0.76 9.7 0.0 3.0 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KII92505.1 - 0.0071 16.4 1.2 1.8 8.6 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF3591 PF12157.8 KII92505.1 - 0.033 12.8 1.2 0.12 11.0 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3591) Sushi_2 PF09014.10 KII92505.1 - 0.064 13.2 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 KII92505.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 KII92505.1 - 0.072 13.5 0.0 0.67 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Spt5_N PF11942.8 KII92505.1 - 0.14 13.2 15.1 0.038 15.0 3.3 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal G-alpha PF00503.20 KII92506.1 - 2.7e-101 339.3 0.0 3.6e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII92506.1 - 8.1e-10 38.4 0.4 6.7e-06 25.7 0.0 2.9 2 1 1 3 3 3 2 ADP-ribosylation factor family NACHT PF05729.12 KII92506.1 - 0.019 14.9 0.0 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Gtr1_RagA PF04670.12 KII92506.1 - 0.022 14.1 0.1 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 KII92506.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KII92506.1 - 0.16 11.7 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IBR PF01485.21 KII92508.1 - 1.1e-11 44.8 35.9 1.1e-06 28.8 12.8 3.3 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain GT87 PF09594.10 KII92509.1 - 0.0016 18.2 0.1 0.0019 18.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 87 Glyoxalase PF00903.25 KII92513.1 - 4.2e-24 85.2 0.1 4.9e-24 84.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KII92513.1 - 2.3e-06 28.3 0.0 3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KII92513.1 - 6.3e-06 26.4 0.0 1.1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KII92513.1 - 0.0039 17.1 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KII92513.1 - 0.024 14.7 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain CppA_N PF14506.6 KII92513.1 - 0.043 13.9 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal F-box-like PF12937.7 KII92516.1 - 0.0014 18.5 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 F-box-like Tim17 PF02466.19 KII92517.1 - 7.9e-30 103.5 8.0 1e-29 103.1 8.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.7 KII92521.1 - 9.2e-06 25.5 0.0 2.7e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII92522.1 - 9.2e-06 25.5 0.0 2.7e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 F-box-like zf-4CXXC_R1 PF10497.9 KII92523.1 - 7.8e-15 54.9 19.5 2e-13 50.4 19.5 2.4 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WSD PF15613.6 KII92523.1 - 0.055 13.9 2.9 0.36 11.3 0.5 3.3 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif F-box-like PF12937.7 KII92525.1 - 0.00013 21.8 1.4 0.00013 21.8 1.4 2.0 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 KII92526.1 - 7e-14 51.5 40.4 3e-13 49.4 39.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4231 PF14015.6 KII92526.1 - 0.76 10.3 0.1 0.76 10.3 0.1 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF4231) F-box-like PF12937.7 KII92527.1 - 1.2e-08 34.7 1.5 4.3e-08 32.9 0.1 2.3 2 1 0 2 2 2 1 F-box-like APG6_N PF17675.1 KII92527.1 - 0.013 16.0 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0061 PF02696.14 KII92528.1 - 9.3e-102 341.2 0.0 1.6e-101 340.4 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family F-box-like PF12937.7 KII92529.1 - 1.6e-10 40.7 0.4 1.7e-09 37.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII92530.1 - 8.3e-12 44.8 0.4 3.7e-11 42.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII92530.1 - 0.0057 16.5 0.0 0.027 14.3 0.0 2.2 1 1 0 1 1 1 1 F-box domain APG6_N PF17675.1 KII92530.1 - 0.021 15.3 0.1 0.028 14.9 0.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 KII92530.1 - 0.056 13.9 1.8 0.078 13.4 1.8 1.2 1 0 0 1 1 1 0 Cell division protein ZapB zf-U1 PF06220.12 KII92531.1 - 1e-10 41.2 2.8 1.6e-10 40.6 2.8 1.3 1 0 0 1 1 1 1 U1 zinc finger UPF0020 PF01170.18 KII92532.1 - 3.8e-08 33.3 0.0 2e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KII92532.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 KII92532.1 - 0.086 12.5 0.0 0.86 9.3 0.0 2.2 2 1 0 2 2 2 0 DNA methylase SWIM PF04434.17 KII92533.1 - 4.5e-06 26.2 0.2 8.8e-06 25.3 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Chitin_synth_1 PF01644.17 KII92534.1 - 1.1e-66 223.8 0.0 5.7e-66 221.5 0.0 2.1 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KII92534.1 - 1.7e-26 92.0 0.0 4.2e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KII92534.1 - 2.5e-23 82.5 12.8 1.3e-17 63.6 0.8 2.8 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KII92534.1 - 2.5e-07 30.8 0.6 2.5e-07 30.8 0.6 2.3 1 1 1 2 2 2 1 Glycosyl transferase family group 2 SLATT_fungal PF18142.1 KII92534.1 - 1.3 9.0 5.2 0.58 10.2 2.5 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain F-box-like PF12937.7 KII92535.1 - 1.5e-11 44.0 0.0 3.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII92535.1 - 6e-05 22.8 0.0 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain Striatin PF08232.12 KII92535.1 - 0.22 12.1 0.0 0.34 11.5 0.0 1.2 1 0 0 1 1 1 0 Striatin family TPP1 PF10341.9 KII92536.1 - 1.6e-08 34.5 0.0 3.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SIR2 PF02146.17 KII92537.1 - 1.4e-33 116.3 0.0 8.9e-33 113.7 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KII92537.1 - 0.0036 17.0 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 KII92537.1 - 0.085 11.8 0.1 0.36 9.7 0.0 1.8 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit PALP PF00291.25 KII92538.1 - 6.2e-67 226.1 0.5 7.1e-67 225.9 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 KII92539.1 - 1.5e-77 259.0 0.0 1.7e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KII92539.1 - 2.3e-15 56.9 0.1 3.1e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KII92539.1 - 4.4e-13 49.1 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KII92539.1 - 8e-12 45.0 1.4 1.7e-07 30.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KII92539.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KII92539.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII92539.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KII92539.1 - 0.017 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LRR_4 PF12799.7 KII92540.1 - 5.1e-13 49.0 11.0 3.5e-05 24.1 0.5 5.3 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII92540.1 - 2.4e-12 46.4 11.5 1.2e-08 34.6 4.6 3.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KII92540.1 - 2.7e-05 23.7 0.5 0.001 18.6 0.3 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KII92540.1 - 0.025 15.1 6.2 16 6.5 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KII92540.1 - 0.085 12.9 12.4 2.9 8.2 1.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat UBA PF00627.31 KII92541.1 - 7.7e-30 102.4 4.7 6.4e-15 54.7 0.1 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 KII92541.1 - 3.1e-21 74.9 10.2 3.1e-21 74.9 10.2 1.8 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 KII92541.1 - 3.2e-19 68.4 1.3 5.3e-19 67.7 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KII92541.1 - 3.5e-06 26.8 2.3 5.4e-06 26.2 2.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KII92541.1 - 0.012 15.4 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 KII92541.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 KII92541.1 - 0.044 13.5 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 CUE domain Ubiquitin_4 PF18036.1 KII92541.1 - 0.13 12.3 0.4 0.4 10.7 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain WIYLD PF10440.9 KII92541.1 - 0.15 11.9 0.0 25 4.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1296 PF06972.11 KII92541.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Ubiquitin_2 PF14560.6 KII92541.1 - 0.19 12.2 0.3 0.34 11.4 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KII92541.1 - 0.19 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MGC-24 PF05283.11 KII92541.1 - 1.6 9.2 5.6 0.3 11.6 1.2 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PLA2_B PF01735.18 KII92542.1 - 8.6e-104 347.7 0.0 1.1e-103 347.3 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain stn_TNFRSF12A PF12191.8 KII92542.1 - 0.0035 17.6 0.1 0.008 16.4 0.1 1.5 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1970 PF09301.10 KII92542.1 - 0.038 14.3 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) THEG4 PF15834.5 KII92542.1 - 0.041 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Testis highly expressed protein 4 SKG6 PF08693.10 KII92542.1 - 0.088 12.2 4.3 0.17 11.3 4.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PTP_tm PF18861.1 KII92542.1 - 0.16 12.0 0.7 0.31 11.0 0.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J ADH_N PF08240.12 KII92543.1 - 2.6e-25 88.4 4.4 7e-25 87.0 4.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII92543.1 - 7.8e-15 55.0 0.0 1.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII92543.1 - 1.7e-06 29.1 0.0 2.5e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KII92543.1 - 6.4e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KII92543.1 - 0.00078 18.8 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cutinase PF01083.22 KII92543.1 - 0.0014 18.7 0.2 0.0024 17.9 0.2 1.4 1 0 0 1 1 1 1 Cutinase ADH_N PF08240.12 KII92544.1 - 2.5e-25 88.5 4.1 5.8e-25 87.3 4.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII92544.1 - 9.5e-15 54.7 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII92544.1 - 1.3e-06 29.5 0.0 2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KII92544.1 - 5.1e-06 25.9 0.0 8.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KII92544.1 - 0.00079 18.8 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cutinase PF01083.22 KII92544.1 - 0.0037 17.2 0.2 0.0069 16.4 0.2 1.5 1 0 0 1 1 1 1 Cutinase Corona_nucleoca PF00937.18 KII92544.1 - 0.0067 15.5 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein GFO_IDH_MocA PF01408.22 KII92544.1 - 0.11 13.3 0.3 0.3 11.9 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_61 PF03443.14 KII92545.1 - 2.4e-57 194.2 0.1 2.7e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.12 KII92546.1 - 1.2e-39 135.2 8.9 2e-39 134.5 8.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) PCM1_C PF15717.5 KII92546.1 - 0.14 10.8 4.1 0.21 10.3 4.1 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus LapA_dom PF06305.11 KII92547.1 - 0.11 12.3 0.8 0.22 11.3 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain YajC PF02699.15 KII92547.1 - 0.27 11.1 0.1 0.55 10.2 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Vps53_N PF04100.12 KII92548.1 - 2.9e-84 283.3 0.0 4.9e-84 282.5 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 KII92548.1 - 4.8e-07 29.9 0.9 3.4e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 KII92548.1 - 4.4e-06 26.2 3.8 9.9e-06 25.0 3.8 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec6 PF06046.13 KII92548.1 - 0.0024 16.3 1.6 0.0026 16.2 0.1 1.8 2 1 1 3 3 3 1 Exocyst complex component Sec6 RINT1_TIP1 PF04437.13 KII92548.1 - 0.021 13.7 0.2 0.021 13.7 0.2 1.9 2 0 0 2 2 2 0 RINT-1 / TIP-1 family DUF2451 PF10474.9 KII92548.1 - 0.022 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Homoserine_dh PF00742.19 KII92548.1 - 0.076 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase DUF1515 PF07439.11 KII92548.1 - 1.5 8.9 6.7 0.34 10.9 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 KII92548.1 - 3.5 7.7 9.3 0.22 11.6 2.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RCC1 PF00415.18 KII92549.1 - 1.4e-16 60.8 0.9 5.9e-08 33.2 0.0 3.9 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII92549.1 - 3.3e-12 45.9 2.4 4.2e-06 26.4 0.5 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat AAA_lid_2 PF17863.1 KII92549.1 - 0.062 13.2 0.5 0.7 9.8 0.2 2.9 2 0 0 2 2 2 0 AAA lid domain Ank_4 PF13637.6 KII92550.1 - 1.7e-08 34.8 0.1 4.8e-07 30.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII92550.1 - 3.6e-06 27.5 0.0 8.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KII92550.1 - 0.00089 19.5 0.0 0.0023 18.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KII92550.1 - 0.0013 19.0 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 KII92550.1 - 0.02 15.4 0.1 0.38 11.5 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_25 PF13649.6 KII92550.1 - 0.056 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KII92551.1 - 0.00055 19.4 0.4 0.0038 16.6 0.3 2.1 1 1 1 2 2 2 1 Protein kinase domain UvdE PF03851.14 KII92552.1 - 1.1e-87 293.9 0.0 1.3e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE BAR PF03114.18 KII92553.1 - 1.3e-51 175.6 2.1 1.5e-51 175.4 2.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KII92553.1 - 0.0018 17.9 2.0 0.049 13.2 0.3 2.1 2 0 0 2 2 2 1 Arfaptin-like domain SYF2 PF08231.12 KII92553.1 - 0.0098 16.3 1.4 0.016 15.6 1.4 1.5 1 1 0 1 1 1 1 SYF2 splicing factor EzrA PF06160.12 KII92553.1 - 0.0099 14.1 1.6 1.1 7.3 0.1 2.1 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA UPF0193 PF05250.11 KII92553.1 - 0.02 14.7 0.0 0.02 14.7 0.0 1.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0193) AAA_13 PF13166.6 KII92553.1 - 0.054 12.1 0.6 0.077 11.6 0.6 1.3 1 0 0 1 1 1 0 AAA domain Metal_resist PF13801.6 KII92553.1 - 0.13 12.5 3.4 12 6.1 1.5 2.4 2 0 0 2 2 2 0 Heavy-metal resistance BAR_3 PF16746.5 KII92553.1 - 0.21 11.3 4.1 1.4 8.5 3.6 2.3 1 1 0 1 1 1 0 BAR domain of APPL family LPD39 PF18858.1 KII92553.1 - 0.4 10.7 7.3 3 7.9 1.4 2.4 2 1 1 3 3 3 0 Large polyvalent protein associated domain 39 AMP-binding PF00501.28 KII92555.1 - 4.8e-43 147.3 0.0 6.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KII92555.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KII92555.1 - 0.055 14.5 0.0 0.12 13.3 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RHD3 PF05879.12 KII92556.1 - 2.3e-250 832.8 0.0 3.2e-250 832.4 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KII92556.1 - 1.1e-06 28.7 0.1 6.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GBP PF02263.19 KII92556.1 - 1.4e-06 27.8 0.2 2.8e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KII92556.1 - 2.4e-05 24.4 0.0 5.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KII92556.1 - 0.0028 17.9 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KII92556.1 - 0.12 12.6 0.4 0.31 11.3 0.1 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_2 PF00891.18 KII92557.1 - 3.1e-30 105.0 0.0 1.9e-29 102.5 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII92557.1 - 0.027 14.3 0.0 0.079 12.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2816 PF10992.8 KII92557.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) Regnase_1_C PF18561.1 KII92558.1 - 0.39 10.5 2.5 0.54 10.0 0.3 2.3 2 1 0 2 2 2 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain HAD_2 PF13419.6 KII92559.1 - 3.5e-18 66.3 0.0 8.3e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII92559.1 - 4.5e-13 50.0 0.0 3e-08 34.2 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KII92559.1 - 0.00013 22.5 0.0 0.00017 22.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KII92559.1 - 0.00025 21.1 0.0 0.09 12.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Glutaredoxin PF00462.24 KII92560.1 - 5e-13 49.1 0.0 9.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KII92560.1 - 0.15 12.5 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Fungal_trans PF04082.18 KII92561.1 - 1.8e-24 86.2 0.0 6.9e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92561.1 - 0.0036 17.4 3.3 0.0067 16.5 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 KII92562.1 - 1.6e-29 102.4 4.6 1.6e-29 102.4 4.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KII92562.1 - 1.6e-06 28.1 0.0 4.1e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like BRO1 PF03097.18 KII92563.1 - 1.7e-22 79.7 0.0 2.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain UTP25 PF06862.12 KII92564.1 - 1.6e-168 561.4 0.0 1.9e-168 561.2 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Topoisom_bac PF01131.20 KII92565.1 - 1.7e-109 366.6 0.0 2e-109 366.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KII92565.1 - 1.3e-20 73.6 0.0 2.4e-19 69.5 0.0 2.6 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.12 KII92565.1 - 2.5e-16 59.5 10.5 2.4e-09 37.1 2.1 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC_3 PF13917.6 KII92565.1 - 3.8e-07 30.0 3.8 0.0019 18.1 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 KII92565.1 - 5.6e-06 26.2 14.5 0.003 17.6 3.3 2.7 2 0 0 2 2 2 2 Zinc knuckle DUF2433 PF10360.9 KII92565.1 - 0.072 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) zf-CCHC_5 PF14787.6 KII92565.1 - 1.8 8.4 11.5 1.1 9.0 1.8 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KII92565.1 - 2.6 8.0 12.7 3.4 7.6 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle Malate_synthase PF01274.22 KII92566.1 - 1.2e-195 650.8 0.0 1.5e-195 650.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase F-box-like PF12937.7 KII92567.1 - 0.0045 16.8 0.3 0.012 15.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII92567.1 - 0.049 13.5 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 F-box domain Hemerythrin PF01814.23 KII92571.1 - 1.1e-13 52.0 0.6 1.5e-13 51.5 0.6 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MMS1_N PF10433.9 KII92572.1 - 1.2e-159 532.1 0.0 1.7e-159 531.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KII92572.1 - 5e-92 308.7 0.0 3.5e-91 305.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region Ribosomal_S4e PF00900.20 KII92572.1 - 0.049 13.5 0.0 2.6 8.0 0.0 2.9 3 0 0 3 3 3 0 Ribosomal family S4e OsmC PF02566.19 KII92573.1 - 5.9e-13 49.2 0.0 1.2e-12 48.1 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein OsmC PF02566.19 KII92574.1 - 5.1e-07 30.1 0.0 6.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein UPF0203 PF05254.12 KII92576.1 - 0.0003 21.0 1.4 0.00075 19.7 1.5 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 KII92576.1 - 0.0015 18.5 0.4 0.092 12.8 0.1 2.5 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KII92576.1 - 0.015 15.4 0.4 0.024 14.8 0.4 1.4 1 1 0 1 1 1 0 CHCH domain Cmc1 PF08583.10 KII92576.1 - 0.021 14.9 0.6 0.088 12.8 0.1 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1746 PF08508.10 KII92577.1 - 1.6e-08 34.9 0.3 2.7e-08 34.2 0.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Tetraspanin PF00335.20 KII92578.1 - 6.8e-07 29.2 8.7 1.1e-06 28.6 8.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 KII92579.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sybindin PF04099.12 KII92580.1 - 1.6e-19 70.2 0.0 2.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.23 KII92581.1 - 3.2e-59 200.4 0.0 5.8e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII92581.1 - 1.1e-17 64.4 0.0 2.6e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII92581.1 - 6.4e-11 42.6 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KII92581.1 - 9.5e-05 21.7 0.1 0.0002 20.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KII92581.1 - 0.00025 21.2 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif RAC_head PF16717.5 KII92581.1 - 0.0096 16.9 0.1 1.3 10.1 0.0 3.0 2 0 0 2 2 2 1 Ribosome-associated complex head domain PsbU PF06514.11 KII92581.1 - 0.036 14.1 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Mito_carr PF00153.27 KII92582.1 - 1e-13 51.0 0.0 1.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3377 PF11857.8 KII92582.1 - 1.6 8.7 3.0 15 5.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Zn_clus PF00172.18 KII92583.1 - 1.2e-06 28.5 5.3 2.2e-06 27.7 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.24 KII92584.1 - 2.9e-14 52.6 16.0 3.8e-07 29.9 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KII92584.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KII92584.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KII92584.1 - 0.016 15.9 2.6 1.7 9.4 0.1 2.3 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KII92584.1 - 0.027 14.7 4.7 0.2 11.9 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Alg14 PF08660.11 KII92585.1 - 3e-55 186.9 0.0 3.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.28 KII92586.1 - 1e-28 97.9 7.1 5.5e-05 22.8 0.0 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KII92586.1 - 1.8e-24 83.8 9.8 1.8e-05 24.6 0.0 8.4 9 0 0 9 9 9 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KII92586.1 - 2.8e-24 85.8 0.0 7.4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 KII92586.1 - 3.5e-20 70.4 20.3 0.0014 18.6 0.0 8.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KII92586.1 - 1.8e-14 53.2 20.8 0.004 17.9 0.1 9.0 6 3 3 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 KII92586.1 - 2e-11 44.3 22.1 2.5e-06 28.0 0.2 7.6 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII92586.1 - 5.3e-11 42.0 5.4 4e-07 29.6 0.8 5.0 3 2 2 5 5 5 2 TPR repeat TPR_12 PF13424.6 KII92586.1 - 8.1e-11 42.1 20.8 0.038 14.3 1.2 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KII92586.1 - 9.9e-09 34.6 21.2 0.3 11.2 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KII92586.1 - 5.9e-07 29.6 12.2 0.11 12.8 0.1 4.9 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KII92586.1 - 9.4e-07 29.3 9.8 0.033 14.7 0.2 5.9 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII92586.1 - 5.2e-06 26.5 5.5 0.2 12.1 0.3 5.3 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII92586.1 - 5.3e-06 26.7 14.8 1.2 10.0 0.0 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.10 KII92586.1 - 3.2e-05 23.1 0.1 0.1 11.6 0.0 2.5 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KII92586.1 - 5.9e-05 22.4 9.0 0.0033 16.7 2.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KII92586.1 - 6.8e-05 22.9 14.3 0.0044 17.1 0.6 5.1 3 1 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KII92586.1 - 0.041 13.8 11.9 0.91 9.5 0.4 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KII92586.1 - 0.073 13.1 0.7 1.6 8.8 0.0 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Clathrin PF00637.20 KII92586.1 - 0.076 12.9 0.7 0.45 10.4 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS GLTSCR1 PF15249.6 KII92587.1 - 1.5e-27 96.0 0.1 3e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein DUF2786 PF10979.8 KII92588.1 - 9.1e-14 51.1 2.5 2.1e-13 49.9 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) DUF1837 PF08878.11 KII92588.1 - 0.064 13.0 0.6 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) DUF4887 PF16228.5 KII92588.1 - 5.1 7.3 14.8 0.64 10.2 9.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) LSM PF01423.22 KII92589.1 - 1.6e-14 53.4 0.2 2.1e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KII92589.1 - 0.017 15.2 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain E3_binding PF02817.17 KII92589.1 - 0.025 14.9 0.1 0.064 13.6 0.1 1.7 1 0 0 1 1 1 0 e3 binding domain SM-ATX PF14438.6 KII92589.1 - 0.043 14.0 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Voltage_CLC PF00654.20 KII92590.1 - 9.6e-94 314.5 23.4 6.2e-93 311.9 21.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 KII92590.1 - 0.0075 16.7 0.0 0.55 10.7 0.0 2.7 2 0 0 2 2 2 1 CBS domain DUF1674 PF07896.12 KII92591.1 - 7.6e-16 58.3 4.0 7.6e-16 58.3 4.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.18 KII92592.1 - 7.1e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92592.1 - 3.6e-09 36.6 11.4 5.9e-09 35.9 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pterin_4a PF01329.19 KII92594.1 - 4.3e-16 58.8 0.5 7.8e-16 58.0 0.1 1.7 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase Ctr PF04145.15 KII92595.1 - 7e-35 120.8 0.6 8.1e-35 120.6 0.6 1.0 1 0 0 1 1 1 1 Ctr copper transporter family UbiA PF01040.18 KII92595.1 - 0.014 14.7 3.9 0.027 13.8 0.7 2.0 2 0 0 2 2 2 0 UbiA prenyltransferase family DUF4191 PF13829.6 KII92595.1 - 0.29 10.5 2.5 0.19 11.0 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) CPBP PF02517.16 KII92595.1 - 1.3 9.5 5.0 1.3 9.4 0.4 2.1 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease Proteasome PF00227.26 KII92596.1 - 1.6e-54 184.3 0.1 3e-54 183.4 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII92596.1 - 0.017 14.8 4.7 0.25 11.1 4.7 2.3 1 1 0 1 1 1 0 Proteasome subunit A N-terminal signature CytochromB561_N PF09786.9 KII92597.1 - 2.4 7.1 6.7 4.1 6.3 6.7 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal F-box-like PF12937.7 KII92598.1 - 4.8e-06 26.4 0.0 1.9e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KII92598.1 - 0.22 11.4 2.4 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 F-box dsrm PF00035.26 KII92599.1 - 3.6e-10 40.4 0.0 7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KII92599.1 - 2.1e-07 31.2 0.0 2.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII92599.1 - 0.056 14.1 0.0 0.12 13.0 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease III domain CHZ PF09649.10 KII92601.1 - 2.2e-15 55.8 0.8 2.2e-15 55.8 0.8 2.8 3 1 0 3 3 3 1 Histone chaperone domain CHZ DNA_pol_phi PF04931.13 KII92601.1 - 0.013 13.6 32.5 0.015 13.5 32.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 KII92601.1 - 0.96 8.6 3.0 0.94 8.6 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC27 PF09507.10 KII92601.1 - 1.2 8.5 17.4 1.3 8.3 17.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Retinal PF15449.6 KII92601.1 - 1.6 6.4 5.6 1.8 6.3 5.6 1.2 1 0 0 1 1 1 0 Retinal protein NOA36 PF06524.12 KII92601.1 - 2.2 7.5 27.9 0.24 10.7 19.3 2.0 2 0 0 2 2 2 0 NOA36 protein BUD22 PF09073.10 KII92601.1 - 9.2 5.5 24.3 10 5.3 24.3 1.0 1 0 0 1 1 1 0 BUD22 Acetyltransf_3 PF13302.7 KII92602.1 - 3.1e-15 57.1 0.1 6.8e-15 56.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII92602.1 - 3e-07 30.7 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII92602.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 KII92602.1 - 0.0009 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SKI PF01202.22 KII92604.1 - 7.2e-10 39.2 0.0 4.8e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KII92604.1 - 1.4e-06 28.9 0.0 1.5e-05 25.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII92604.1 - 7.7e-05 22.9 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KII92604.1 - 0.014 15.9 0.0 0.051 14.1 0.0 1.7 1 1 0 2 2 2 0 ABC transporter Cytidylate_kin PF02224.18 KII92604.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 KII92604.1 - 0.025 14.9 0.1 0.065 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 KII92604.1 - 0.028 14.5 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA PF00004.29 KII92604.1 - 0.032 14.7 0.3 0.13 12.7 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KII92604.1 - 0.044 13.4 0.1 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KII92604.1 - 0.049 13.5 0.0 4.5 7.1 0.0 2.2 2 1 0 2 2 2 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 KII92604.1 - 0.086 12.7 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase APS_kinase PF01583.20 KII92604.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 KII92604.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KII92604.1 - 0.13 12.1 0.1 0.41 10.5 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KII92604.1 - 0.13 12.6 0.2 0.33 11.3 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 KII92604.1 - 0.2 11.3 0.1 7.8 6.1 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase Rpr2 PF04032.16 KII92605.1 - 1.4e-25 89.3 0.5 3.5e-25 88.1 0.1 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 KII92605.1 - 0.14 12.3 0.3 0.21 11.7 0.3 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain Ribosomal_S8e PF01201.22 KII92606.1 - 2.6e-49 166.9 0.6 4.7e-49 166.1 0.6 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Yip1 PF04893.17 KII92607.1 - 8.1e-07 28.9 10.7 1.2e-06 28.3 10.7 1.4 1 0 0 1 1 1 1 Yip1 domain Pterin_4a PF01329.19 KII92608.1 - 3e-14 52.9 0.0 5.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase eIF3g PF12353.8 KII92608.1 - 0.007 16.7 17.2 0.14 12.6 0.1 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-C2H2_10 PF16588.5 KII92608.1 - 0.11 12.2 0.4 0.11 12.2 0.4 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger Aldo_ket_red PF00248.21 KII92609.1 - 9.3e-28 97.3 0.0 2.5e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 KII92610.1 - 8.8e-09 35.0 23.4 0.001 19.0 0.6 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 KII92610.1 - 0.0057 16.4 4.2 0.052 13.4 0.6 4.2 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.6 KII92610.1 - 0.029 14.1 20.2 0.33 10.7 0.3 4.3 4 0 0 4 4 4 0 Zinc knuckle PHD_4 PF16866.5 KII92610.1 - 3.2 7.9 7.8 0.95 9.6 0.7 2.6 1 1 1 2 2 2 0 PHD-finger zf-CCHC_5 PF14787.6 KII92610.1 - 4.2 7.2 25.1 0.76 9.5 3.8 4.3 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 KII92610.1 - 7.4 6.6 15.3 12 6.0 0.2 4.3 3 1 1 4 4 4 0 Zinc knuckle DUF3895 PF13034.6 KII92611.1 - 0.097 12.7 0.0 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) FAD_binding_3 PF01494.19 KII92612.1 - 3.9e-74 250.0 0.0 5.2e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII92612.1 - 1.5e-07 30.9 2.1 0.00017 21.0 0.1 2.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII92612.1 - 5.2e-07 29.6 1.3 0.002 17.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII92612.1 - 6.4e-06 25.5 0.1 1.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KII92612.1 - 1.6e-05 23.8 0.9 6e-05 21.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KII92612.1 - 3.1e-05 24.5 0.2 0.028 15.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII92612.1 - 5.1e-05 23.4 0.0 0.00014 22.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KII92612.1 - 0.00092 18.4 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KII92612.1 - 0.0026 17.2 0.2 0.0038 16.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KII92612.1 - 0.0045 16.3 0.1 0.0079 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KII92612.1 - 0.0051 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII92612.1 - 0.067 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 KII92612.1 - 0.12 11.9 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 KII92612.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KII92612.1 - 0.14 11.2 0.2 0.26 10.3 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Yippee-Mis18 PF03226.14 KII92613.1 - 3.5e-14 52.9 0.0 4.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Dioxygenase_C PF00775.21 KII92614.1 - 3.4e-08 33.2 0.0 3.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase RdRP PF05183.12 KII92616.1 - 6.8e-103 345.3 0.0 1.3e-102 344.4 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase Amidohydro_2 PF04909.14 KII92617.1 - 2.8e-26 93.0 0.0 8.9e-26 91.3 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase RRM_1 PF00076.22 KII92619.1 - 1.3e-16 60.1 0.1 5.1e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII92619.1 - 0.0013 18.3 0.0 0.48 10.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 KII92620.1 - 1.3e-13 51.5 0.0 2.7e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII92620.1 - 1.2e-12 47.8 0.1 2.5e-12 46.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KII92620.1 - 9.6e-11 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KII92620.1 - 5e-10 39.9 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII92620.1 - 4.5e-08 33.1 0.0 2e-07 31.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KII92620.1 - 3.6e-07 29.7 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KII92620.1 - 6.6e-07 28.6 0.0 9.4e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KII92620.1 - 2.9e-06 26.9 0.1 4.9e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KII92620.1 - 3.1e-06 27.8 0.0 6.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KII92620.1 - 1.6e-05 24.4 0.2 3.7e-05 23.2 0.2 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 KII92620.1 - 0.00039 20.2 0.1 0.00063 19.5 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 KII92620.1 - 0.00054 19.9 0.1 0.00085 19.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KII92620.1 - 0.00062 19.8 0.0 0.00092 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII92620.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 KII92620.1 - 0.004 16.5 0.1 0.01 15.2 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KII92620.1 - 0.0062 17.5 0.0 0.013 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KII92620.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KII92620.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2367 PF10164.9 KII92621.1 - 9.8e-07 29.2 5.0 1.9e-06 28.3 5.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) LRR_4 PF12799.7 KII92622.1 - 0.00053 20.3 2.0 38 4.9 0.0 5.9 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII92624.1 - 1 9.2 7.3 69 3.3 0.1 5.2 6 1 0 6 6 6 0 Leucine rich repeat Exo_endo_phos PF03372.23 KII92626.1 - 2e-17 63.5 0.4 3.9e-16 59.3 0.4 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KII92626.1 - 3.3e-16 58.8 13.2 5.6e-10 38.8 3.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KII92626.1 - 4.7e-11 42.7 7.8 2.8e-05 24.4 0.7 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII92626.1 - 0.00097 19.4 5.3 2.5 9.0 0.2 4.6 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 KII92626.1 - 2 8.7 8.1 7.1 7.0 0.4 4.1 5 0 0 5 5 5 0 Leucine Rich repeat MDD_C PF18376.1 KII92627.1 - 2.6e-74 249.0 0.0 3.4e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KII92627.1 - 1.1e-06 28.7 5.5 2.3e-06 27.7 5.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Glyco_hydro_cc PF11790.8 KII92629.1 - 8.8e-75 251.3 4.1 1e-74 251.1 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SBP_bac_11 PF13531.6 KII92629.1 - 0.093 12.5 1.6 0.6 9.8 1.6 2.2 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein PIG-U PF06728.13 KII92631.1 - 1.2e-104 350.5 26.7 1.3e-104 350.3 26.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U peroxidase PF00141.23 KII92632.1 - 8.2e-44 150.0 0.0 1.4e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-LYAR PF08790.11 KII92634.1 - 6.7e-14 51.5 4.2 1.3e-13 50.6 4.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Autophagy_N PF03986.13 KII92635.1 - 1e-42 145.4 0.0 1.2e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_N PF03986.13 KII92636.1 - 1.5e-43 148.0 0.0 2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain DUF3792 PF12670.7 KII92637.1 - 2.4 8.3 20.8 0.64 10.2 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) 12TM_1 PF09847.9 KII92637.1 - 3.6 6.6 23.1 4.7 6.2 23.1 1.0 1 0 0 1 1 1 0 Membrane protein of 12 TMs Autophagy_N PF03986.13 KII92638.1 - 1.7e-42 144.6 0.1 4.2e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KII92638.1 - 1e-16 61.2 0.3 1.8e-16 60.4 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KII92638.1 - 1.4e-12 46.9 2.9 2.6e-12 46.0 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CUE PF02845.16 KII92639.1 - 8.8e-10 38.1 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain Tyrosinase PF00264.20 KII92640.1 - 1.2e-29 104.2 10.2 1.7e-29 103.7 10.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyridoxal_deC PF00282.19 KII92641.1 - 7.9e-16 57.7 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KII92641.1 - 1.2e-05 24.5 0.1 0.00033 19.7 0.1 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KII92641.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.29 KII92644.1 - 2.8e-08 34.0 0.0 6.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KII92644.1 - 1.8e-07 31.7 0.5 2.8e-05 24.6 0.3 3.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KII92644.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like ATP-synt_C PF00137.21 KII92645.1 - 1.5e-24 86.1 26.9 1.3e-15 57.5 12.5 2.5 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 KII92645.1 - 3.5 7.3 10.7 0.38 10.4 4.5 2.6 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Arf PF00025.21 KII92646.1 - 2.3e-36 124.8 0.0 6e-36 123.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KII92646.1 - 1.7e-10 40.6 0.0 2.4e-05 23.6 0.0 2.7 1 1 2 3 3 3 2 G-protein alpha subunit Roc PF08477.13 KII92646.1 - 1.1e-09 38.6 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KII92646.1 - 3.4e-07 30.0 0.0 5.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KII92646.1 - 5.7e-06 26.4 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII92646.1 - 5.8e-06 25.8 0.0 7.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KII92646.1 - 2.5e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KII92646.1 - 0.00011 21.8 0.0 0.051 13.1 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KII92646.1 - 0.00085 19.9 0.3 0.0039 17.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KII92646.1 - 0.0015 19.1 0.2 0.0047 17.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KII92646.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.8 1 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII92646.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KII92646.1 - 0.005 16.8 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KII92646.1 - 0.02 15.3 0.5 0.043 14.2 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KII92646.1 - 0.023 13.9 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KII92646.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 KII92646.1 - 0.027 14.2 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.6 KII92646.1 - 0.029 14.9 0.2 0.064 13.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KII92646.1 - 0.03 14.5 0.3 0.093 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KII92646.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 KII92646.1 - 0.065 12.8 0.1 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KII92646.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 KII92646.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain adh_short PF00106.25 KII92647.1 - 5.7e-40 136.9 0.2 8.2e-40 136.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII92647.1 - 7.9e-33 114.0 0.0 1.1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92647.1 - 3.3e-05 23.9 0.3 0.00029 20.8 0.3 2.0 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KII92647.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Voltage_CLC PF00654.20 KII92648.1 - 8.6e-87 291.7 36.7 8.6e-87 291.7 36.7 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KII92648.1 - 2.6e-12 47.0 0.5 9e-06 26.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain RIBIOP_C PF04950.12 KII92651.1 - 2e-121 404.9 0.0 2e-121 404.9 0.0 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KII92651.1 - 3e-17 62.5 0.0 2.5e-16 59.5 0.0 2.5 1 1 0 1 1 1 1 AARP2CN (NUC121) domain Muskelin_N PF06588.11 KII92652.1 - 2.4e-15 57.0 0.0 2.8e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Muskelin N-terminus Muskelin_N PF06588.11 KII92653.1 - 2.2e-36 125.7 0.0 1.8e-35 122.7 0.0 2.0 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_4 PF13418.6 KII92653.1 - 1.7e-24 85.6 2.8 9.3e-07 28.8 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KII92653.1 - 1.1e-23 82.7 0.6 2.1e-07 30.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KII92653.1 - 4.9e-23 80.9 10.3 4.7e-09 36.3 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KII92653.1 - 4.3e-18 64.9 3.4 0.0003 21.0 0.0 6.0 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 KII92653.1 - 1.7e-15 56.3 8.3 8.4e-08 31.7 0.2 5.7 6 0 0 6 6 6 4 Kelch motif Prefoldin_2 PF01920.20 KII92654.1 - 4.4e-22 78.0 10.0 5.3e-22 77.8 10.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dam1 PF08653.10 KII92654.1 - 0.00051 19.8 2.5 0.45 10.4 0.8 2.5 2 0 0 2 2 2 2 DASH complex subunit Dam1 Laminin_II PF06009.12 KII92654.1 - 0.0006 19.8 2.0 0.052 13.6 0.3 2.1 2 0 0 2 2 2 1 Laminin Domain II Prefoldin PF02996.17 KII92654.1 - 0.0015 18.4 9.1 0.015 15.2 1.3 2.1 1 1 1 2 2 2 2 Prefoldin subunit Seryl_tRNA_N PF02403.22 KII92654.1 - 0.0018 18.5 6.6 0.19 12.0 0.5 2.2 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 KII92654.1 - 0.0048 17.2 6.2 0.2 12.0 1.9 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SLY PF12485.8 KII92654.1 - 0.012 16.3 4.0 1.7 9.4 0.1 2.0 1 1 1 2 2 2 0 Lymphocyte signaling adaptor protein HTH_ParB PF17762.1 KII92654.1 - 0.013 15.3 0.3 0.025 14.4 0.3 1.6 1 0 0 1 1 1 0 HTH domain found in ParB protein DivIC PF04977.15 KII92654.1 - 0.015 15.0 6.1 0.67 9.8 1.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DASH_Dad4 PF08650.10 KII92654.1 - 0.019 15.0 0.4 2.3 8.2 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad4 TMF_DNA_bd PF12329.8 KII92654.1 - 0.02 14.9 2.6 0.02 14.9 2.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KII92654.1 - 0.03 14.4 8.1 0.038 14.1 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 KII92654.1 - 0.03 14.4 3.1 3.6 7.7 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF5082 PF16888.5 KII92654.1 - 0.033 14.5 4.8 0.12 12.7 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) MAP65_ASE1 PF03999.12 KII92654.1 - 0.034 12.9 7.9 0.039 12.6 7.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FlxA PF14282.6 KII92654.1 - 0.051 13.6 7.4 0.32 11.0 0.9 2.2 2 0 0 2 2 2 0 FlxA-like protein XhlA PF10779.9 KII92654.1 - 0.054 13.7 6.2 0.31 11.3 0.4 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Tox-URI2 PF15653.6 KII92654.1 - 0.057 13.7 0.8 4.1 7.7 0.0 2.4 1 1 1 2 2 2 0 URI fold toxin 2 DUF16 PF01519.16 KII92654.1 - 0.059 13.9 6.9 0.76 10.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FliD_C PF07195.12 KII92654.1 - 0.075 12.4 2.9 0.26 10.7 0.1 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF919 PF06034.11 KII92654.1 - 0.088 12.7 3.6 1.1 9.1 0.1 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) TFA2_Winged_2 PF18121.1 KII92654.1 - 0.096 12.4 4.7 1.6 8.4 1.0 2.5 2 1 0 2 2 2 0 TFA2 Winged helix domain 2 V_ATPase_I PF01496.19 KII92654.1 - 0.12 10.2 5.1 0.14 10.1 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KII92654.1 - 0.12 12.7 6.1 2 8.9 1.1 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Rho_Binding PF08912.11 KII92654.1 - 0.13 13.1 8.8 0.95 10.3 2.6 2.3 2 0 0 2 2 2 0 Rho Binding Spc24 PF08286.11 KII92654.1 - 0.17 12.1 11.9 1.7 8.9 0.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SKA2 PF16740.5 KII92654.1 - 0.19 11.5 6.2 0.14 11.9 3.5 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Shugoshin_N PF07558.11 KII92654.1 - 0.26 11.2 4.1 0.36 10.7 1.5 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Plk4_PB2 PF18409.1 KII92654.1 - 0.3 11.8 4.0 11 6.8 0.3 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 YabA PF06156.13 KII92654.1 - 0.3 11.7 7.2 6.3 7.5 2.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF3958 PF13125.6 KII92654.1 - 0.31 11.3 11.5 1.9 8.7 4.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Exonuc_VII_L PF02601.15 KII92654.1 - 0.36 10.4 3.9 0.44 10.1 3.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MitMem_reg PF13012.6 KII92654.1 - 0.5 10.8 3.3 0.78 10.2 3.3 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DHR10 PF18595.1 KII92654.1 - 0.66 10.0 13.6 4.6 7.3 13.6 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain PCRF PF03462.18 KII92654.1 - 0.69 9.8 10.0 1.4 8.8 10.0 1.5 1 1 0 1 1 1 0 PCRF domain Helo_like_N PF17111.5 KII92654.1 - 0.69 9.2 10.2 0.66 9.3 3.5 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Remorin_C PF03763.13 KII92654.1 - 0.94 9.4 7.5 0.33 10.9 2.1 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region DUF4140 PF13600.6 KII92654.1 - 1.9 9.0 8.7 1.9 9.0 2.5 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spore_III_AB PF09548.10 KII92654.1 - 2.1 8.4 6.5 3.8 7.6 6.5 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Spc7 PF08317.11 KII92654.1 - 2.8 6.8 14.1 6.9 5.5 14.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 KII92654.1 - 3.3 6.2 7.2 7.7 5.0 7.3 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A UPF0449 PF15136.6 KII92654.1 - 3.5 8.1 10.3 4.5 7.8 3.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 ZapB PF06005.12 KII92654.1 - 3.9 8.0 13.2 61 4.2 13.2 2.2 1 1 0 1 1 1 0 Cell division protein ZapB TMPIT PF07851.13 KII92654.1 - 4.9 6.3 7.8 37 3.4 7.8 1.9 1 1 0 1 1 1 0 TMPIT-like protein EMP24_GP25L PF01105.24 KII92654.1 - 5.4 6.9 7.1 5.5 6.9 2.3 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD APG6_N PF17675.1 KII92654.1 - 7 7.2 19.1 16 6.0 8.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region SET PF00856.28 KII92655.1 - 3.1e-14 53.7 0.0 6.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KII92655.1 - 8.7e-12 45.9 0.0 1.7e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding FAD_binding_3 PF01494.19 KII92656.1 - 5.3e-21 75.2 0.1 1.2e-20 74.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KII92656.1 - 1.2e-06 28.2 1.1 0.013 14.8 1.2 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KII92656.1 - 1.6e-06 27.3 2.7 0.0024 16.8 1.3 2.2 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 KII92656.1 - 4.7e-06 26.8 2.3 1.1e-05 25.6 2.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KII92656.1 - 0.00021 20.6 4.6 0.0034 16.7 2.3 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII92656.1 - 0.00049 19.4 0.8 0.00096 18.5 0.8 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KII92656.1 - 0.0021 17.2 1.6 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KII92656.1 - 0.0031 16.3 0.5 0.0075 15.0 0.5 1.6 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KII92656.1 - 0.0046 16.1 4.9 0.0046 16.1 4.9 1.7 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KII92656.1 - 0.0081 15.5 0.5 0.011 15.1 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KII92656.1 - 0.017 14.7 13.9 0.33 10.5 13.9 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KII92656.1 - 0.058 14.0 1.2 0.26 11.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII92656.1 - 0.14 12.1 3.6 3.7 7.5 3.6 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 KII92656.1 - 0.19 10.8 3.7 5.1 6.1 4.6 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KII92656.1 - 7.4 5.7 4.9 52 3.0 5.6 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gti1_Pac2 PF09729.9 KII92657.1 - 9.2e-24 84.5 0.2 1.5e-20 74.1 0.0 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KII92659.1 - 2.1e-32 112.7 0.1 5.9e-28 98.2 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family zf-MYND PF01753.18 KII92660.1 - 2.2e-05 24.5 10.2 6.7e-05 22.9 10.2 1.8 1 1 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII92660.1 - 0.086 13.2 9.5 0.23 11.8 9.5 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding tRNA-synt_1e PF01406.19 KII92661.1 - 1.3e-126 422.1 0.1 1.9e-126 421.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KII92661.1 - 1.9e-08 33.5 1.0 6.1e-05 21.9 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KII92661.1 - 4.4e-05 21.9 1.1 0.0015 16.9 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KII92661.1 - 0.00077 19.9 0.0 0.0038 17.7 0.0 2.3 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KII92661.1 - 0.087 11.7 0.5 2.4 7.0 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sorb PF02208.16 KII92661.1 - 0.12 12.2 0.3 3.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Sorbin homologous domain Ribosomal_L30_N PF08079.12 KII92661.1 - 3.1 8.1 13.8 28 5.0 11.1 2.5 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain 40S_SA_C PF16122.5 KII92661.1 - 4.6 8.7 7.4 2.2 9.7 3.8 2.4 2 0 0 2 2 2 0 40S ribosomal protein SA C-terminus HMG_box PF00505.19 KII92663.1 - 1.7e-11 44.4 3.8 1.7e-11 44.4 3.8 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII92663.1 - 3.6e-09 37.1 4.6 3.6e-09 37.1 4.6 2.4 1 1 1 2 2 2 1 HMG-box domain SOBP PF15279.6 KII92663.1 - 0.23 12.0 10.7 0.29 11.7 10.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.9 KII92663.1 - 6.6 4.9 12.9 8.1 4.6 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rrn6 PF10214.9 KII92663.1 - 7.9 4.8 15.5 10 4.5 15.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RR_TM4-6 PF06459.12 KII92663.1 - 9.9 5.9 10.8 15 5.3 10.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAF PF01590.26 KII92665.1 - 0.053 14.2 0.0 0.072 13.7 0.0 1.4 1 0 0 1 1 1 0 GAF domain F-box-like PF12937.7 KII92666.1 - 0.0015 18.3 1.3 0.0064 16.4 1.3 2.1 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KII92666.1 - 0.03 14.1 0.1 0.36 10.6 0.1 2.4 1 1 0 1 1 1 0 Leucine rich repeat F-box-like PF12937.7 KII92667.1 - 0.017 15.0 1.7 0.4 10.6 1.7 2.6 1 1 0 1 1 1 0 F-box-like GLTP PF08718.11 KII92668.1 - 9.5e-44 149.3 0.0 1.2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) TFIIA PF03153.13 KII92669.1 - 5e-56 191.5 0.0 3.4e-35 122.8 0.1 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KII92669.1 - 8.7 5.4 9.0 9.7 5.3 9.0 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein MRP-S26 PF14943.6 KII92670.1 - 0.067 13.1 7.0 0.1 12.5 7.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Smac_DIABLO PF09057.10 KII92670.1 - 0.79 9.0 7.4 1.1 8.5 7.4 1.1 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases DUF3844 PF12955.7 KII92671.1 - 6.4e-31 106.6 5.3 1e-30 106.0 5.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) THF_DHG_CYH PF00763.23 KII92671.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DEAD PF00270.29 KII92674.1 - 9.1e-09 35.3 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase MeaB PF03308.16 KII92675.1 - 0.0076 15.3 1.4 0.0076 15.3 1.4 1.5 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Borrelia_P83 PF05262.11 KII92675.1 - 0.12 10.8 21.3 0.14 10.6 21.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SLC12 PF03522.15 KII92675.1 - 0.66 8.9 9.7 0.78 8.7 9.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Asp-B-Hydro_N PF05279.11 KII92675.1 - 1 9.3 20.5 1.3 9.1 20.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dsh_C PF12316.8 KII92675.1 - 1.9 8.9 8.3 2.5 8.4 8.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CAF-1_p150 PF11600.8 KII92675.1 - 2.5 7.8 44.4 0.15 11.8 38.5 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.12 KII92675.1 - 4.2 7.6 12.5 5 7.3 12.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family ALMT PF11744.8 KII92675.1 - 5.3 5.8 9.2 6 5.6 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SOBP PF15279.6 KII92675.1 - 6.6 7.3 7.0 8.1 7.0 7.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Plasmodium_Vir PF05795.11 KII92675.1 - 7.3 5.9 9.4 8.4 5.7 9.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein V_ATPase_I PF01496.19 KII92675.1 - 7.9 4.3 9.4 11 3.8 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 KII92675.1 - 9.2 3.2 8.0 9.9 3.1 8.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SAPS PF04499.15 KII92675.1 - 9.5 4.9 9.8 9.7 4.8 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CHAD PF05235.14 KII92676.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 CHAD domain CRAL_TRIO PF00650.20 KII92678.1 - 3.5e-10 39.8 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Metallophos PF00149.28 KII92679.1 - 3.8e-35 122.2 0.4 4.8e-35 121.9 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KII92679.1 - 0.074 13.5 0.8 0.15 12.5 0.8 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KII92679.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-C2H2_4 PF13894.6 KII92680.1 - 7.4e-07 29.5 14.4 0.011 16.5 7.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KII92680.1 - 1.5e-06 28.3 16.6 0.007 16.8 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Tmemb_55A PF09788.9 KII92680.1 - 0.0038 16.4 2.2 0.011 14.8 2.2 1.8 1 0 0 1 1 1 1 Transmembrane protein 55A zf-BED PF02892.15 KII92680.1 - 0.0041 17.1 7.4 0.38 10.8 0.8 2.4 1 1 1 2 2 2 2 BED zinc finger Zn-ribbon_8 PF09723.10 KII92680.1 - 0.01 16.0 2.6 0.028 14.5 2.6 1.7 1 1 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 KII92680.1 - 0.026 14.6 0.4 0.052 13.6 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-nanos PF05741.13 KII92680.1 - 0.089 13.0 0.7 0.089 13.0 0.7 2.5 1 1 1 2 2 2 0 Nanos RNA binding domain zf-C2H2_3rep PF18868.1 KII92680.1 - 0.095 13.4 0.0 0.095 13.4 0.0 1.9 3 0 0 3 3 1 0 Zinc finger C2H2-type, 3 repeats Nudix_N_2 PF14803.6 KII92680.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.7 2 1 1 3 3 3 0 Nudix N-terminal HypA PF01155.19 KII92680.1 - 0.21 11.6 0.3 0.32 11.0 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KII92680.1 - 0.42 10.6 2.5 4 7.5 0.2 2.4 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_jaz PF12171.8 KII92680.1 - 0.63 10.4 12.1 2.6 8.4 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KII92680.1 - 1.8 9.1 19.3 0.096 13.2 5.2 3.9 5 0 0 5 5 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 KII92680.1 - 2.3 8.3 10.8 0.46 10.5 0.3 3.0 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KII92680.1 - 2.6 7.9 11.9 1.1 9.1 0.1 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KII92680.1 - 3.3 8.3 5.1 8.6 7.0 5.1 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Zn_ribbon_SprT PF17283.2 KII92680.1 - 5.8 6.9 10.9 1.4 8.9 6.2 2.3 2 1 1 3 3 2 0 SprT-like zinc ribbon domain Rubredoxin_2 PF18073.1 KII92680.1 - 8.2 6.2 9.0 0.51 10.1 1.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-CCCH PF00642.24 KII92681.1 - 2e-09 37.1 2.7 4.9e-09 35.9 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KII92681.1 - 2.8e-08 33.5 5.5 4.9e-08 32.7 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII92681.1 - 1.6e-06 28.0 8.9 2.7e-06 27.2 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII92681.1 - 5.1e-06 26.4 7.0 1e-05 25.4 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KII92681.1 - 1.4e-05 24.8 8.7 2.6e-05 24.0 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KII92681.1 - 1.5e-05 24.9 4.4 3e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KII92681.1 - 9.2e-05 22.5 3.0 0.00021 21.4 3.0 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 KII92681.1 - 0.00014 21.6 9.5 0.00026 20.8 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII92681.1 - 0.00064 19.8 6.6 0.0015 18.6 6.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KII92681.1 - 0.0011 19.3 7.9 0.002 18.4 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KII92681.1 - 0.0015 18.3 2.9 0.0031 17.3 2.9 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KII92681.1 - 0.018 14.9 7.4 0.034 14.0 7.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Hamartin PF04388.12 KII92681.1 - 0.19 10.3 4.7 0.23 10.1 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein zf-RanBP PF00641.18 KII92681.1 - 3.2 7.2 7.3 0.079 12.3 0.9 1.7 2 0 0 2 2 1 0 Zn-finger in Ran binding protein and others Lipase_GDSL PF00657.22 KII92682.1 - 2.1e-08 34.4 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII92682.1 - 5.8e-06 26.8 0.3 1.6e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII92683.1 - 1.7e-07 31.4 0.0 2.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII92683.1 - 5.2e-05 23.7 0.1 7.7e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family bZIP_2 PF07716.15 KII92684.1 - 5.2e-10 39.3 9.9 9e-10 38.5 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KII92684.1 - 1.7e-05 24.8 5.4 3.6e-05 23.8 5.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor HMMR_N PF15905.5 KII92684.1 - 0.024 14.1 0.6 0.042 13.3 0.6 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HMG_box PF00505.19 KII92685.1 - 3.6e-12 46.5 0.1 5.9e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII92685.1 - 0.00027 21.5 0.0 0.00044 20.8 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain LysM PF01476.20 KII92686.1 - 2.7e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain NUDIX PF00293.28 KII92689.1 - 1.6e-16 60.6 0.0 3.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KII92689.1 - 1.8e-13 51.0 0.9 4.1e-13 49.9 0.9 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KII92689.1 - 0.0055 16.3 1.1 0.012 15.3 1.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain HMG_box PF00505.19 KII92689.1 - 0.015 15.7 4.0 0.033 14.6 4.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box zinc_ribbon_2 PF13240.6 KII92689.1 - 0.032 14.0 0.9 0.062 13.0 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KII92689.1 - 0.13 12.2 0.5 0.32 11.0 0.2 1.8 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2 PF00096.26 KII92690.1 - 5.2e-12 45.5 16.8 0.00042 20.6 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII92690.1 - 1.7e-08 34.6 12.7 0.021 15.6 1.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII92690.1 - 0.0011 19.2 2.6 6.5 7.2 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KII92690.1 - 0.0039 17.5 12.5 0.11 12.9 1.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.15 KII92690.1 - 0.04 13.9 0.5 0.093 12.8 0.5 1.6 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.7 KII92690.1 - 0.063 13.7 5.5 1.3 9.5 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KII92690.1 - 0.077 13.0 8.1 0.2 11.7 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 KII92690.1 - 0.095 12.9 2.7 0.21 11.9 2.7 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain Fer4_9 PF13187.6 KII92690.1 - 0.2 11.9 2.4 0.2 11.9 0.9 1.7 2 0 0 2 2 1 0 4Fe-4S dicluster domain zf-C2H2_8 PF15909.5 KII92690.1 - 0.46 10.8 6.4 1.2 9.5 3.3 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn_ribbon_SprT PF17283.2 KII92690.1 - 0.52 10.3 3.5 1.1 9.2 3.5 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2HE PF16278.5 KII92690.1 - 2.4 8.7 5.3 0.78 10.2 1.5 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KII92690.1 - 4.1 7.2 7.3 7.1 6.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Mito_carr PF00153.27 KII92691.1 - 2.5e-61 203.6 7.0 5.3e-20 71.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KII92692.1 - 1.2e-10 41.2 0.0 5.4e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII92692.1 - 5.7e-05 22.5 0.0 0.00013 21.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92692.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KII92693.1 - 2.6e-09 36.9 0.0 2.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92693.1 - 6.8e-05 22.3 0.0 0.00019 20.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92693.1 - 0.086 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KII92695.1 - 1e-10 41.4 0.0 9.5e-09 35.0 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII92695.1 - 3.2e-05 23.3 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92695.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SRPRB PF09439.10 KII92696.1 - 0.034 13.6 0.1 0.07 12.6 0.1 1.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit TP6A_N PF04406.14 KII92696.1 - 0.24 11.4 1.3 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Type IIB DNA topoisomerase Pkinase PF00069.25 KII92697.1 - 2e-10 40.5 0.0 3.8e-09 36.3 0.0 2.2 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92697.1 - 0.00021 20.7 0.0 0.00061 19.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KII92699.1 - 1e-10 41.4 0.0 1.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92699.1 - 3.2e-05 23.3 0.0 7.1e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92699.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase CoA_binding_2 PF13380.6 KII92700.1 - 2.6e-30 105.3 0.0 3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KII92700.1 - 0.1 13.3 0.0 0.14 12.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain PALP PF00291.25 KII92701.1 - 8.6e-53 179.7 0.0 1e-49 169.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Myb_DNA-binding PF00249.31 KII92702.1 - 1.5e-11 44.2 0.1 4.1e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KII92702.1 - 1.6e-10 41.2 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KII92702.1 - 0.0002 21.5 0.0 0.00044 20.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_28 PF13521.6 KII92702.1 - 0.15 12.3 0.9 0.33 11.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 KII92703.1 - 2.6e-22 79.1 24.8 1.8e-05 25.2 0.0 9.7 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 KII92703.1 - 9.1e-21 72.8 19.7 4.2e-05 23.2 0.0 10.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KII92703.1 - 5.3e-20 69.9 35.7 0.00069 19.5 0.1 13.6 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 KII92703.1 - 7.1e-15 53.9 21.2 0.019 15.2 0.0 12.1 12 1 1 13 13 13 4 Tetratricopeptide repeat TPR_12 PF13424.6 KII92703.1 - 8e-15 54.9 29.3 1.5e-05 25.2 1.4 9.2 8 2 3 11 11 10 6 Tetratricopeptide repeat TPR_7 PF13176.6 KII92703.1 - 3.1e-08 33.1 19.6 0.14 12.3 0.1 9.0 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII92703.1 - 4.6e-08 33.2 31.8 0.054 14.2 0.1 10.4 12 1 0 12 12 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 KII92703.1 - 3.3e-07 30.2 11.8 3.3 8.3 0.0 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII92703.1 - 3.8e-06 27.0 10.7 0.12 12.6 0.4 5.7 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KII92703.1 - 6.6e-06 25.8 26.8 0.017 15.0 0.3 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII92703.1 - 0.00018 22.0 46.6 1.3 10.0 0.2 13.4 10 4 5 15 15 14 3 Tetratricopeptide repeat TPR_4 PF07721.14 KII92703.1 - 0.0041 17.6 0.2 1.3 9.9 0.0 5.3 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII92703.1 - 0.0045 16.7 8.5 0.75 9.5 0.1 6.7 7 1 1 8 8 8 1 TPR repeat TPR_16 PF13432.6 KII92703.1 - 0.16 12.7 42.4 0.44 11.3 0.1 9.6 9 2 3 12 12 10 0 Tetratricopeptide repeat DUF2989 PF11207.8 KII92703.1 - 0.65 9.7 0.0 0.65 9.7 0.0 5.0 6 0 0 6 6 5 0 Protein of unknown function (DUF2989) ADH_zinc_N PF00107.26 KII92704.1 - 4.3e-16 59.1 0.0 7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII92704.1 - 1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KII92704.1 - 3.1e-08 34.7 0.0 5.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KII92704.1 - 0.0008 19.7 0.1 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain DUF2855 PF11017.8 KII92704.1 - 0.0033 17.2 0.3 0.0079 16.0 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2855) zf-HIT PF04438.16 KII92705.1 - 2.3e-08 33.8 14.0 3.4e-08 33.2 14.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KII92705.1 - 0.11 12.6 10.2 0.19 11.9 10.2 1.3 1 0 0 1 1 1 0 MYND finger Tnp_zf-ribbon_2 PF13842.6 KII92705.1 - 0.44 11.4 9.5 1.1 10.1 9.5 1.7 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-B_box PF00643.24 KII92705.1 - 4.3 7.6 9.8 6.8 6.9 9.8 1.3 1 0 0 1 1 1 0 B-box zinc finger ADH_N_2 PF16884.5 KII92707.1 - 4e-18 65.3 0.0 8.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KII92707.1 - 1.9e-16 60.2 0.0 3.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII92707.1 - 6.1e-07 30.6 0.0 1.1e-06 29.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KII92707.1 - 0.00056 20.2 0.1 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain CDH-cyt PF16010.5 KII92708.1 - 1.1e-13 51.3 5.1 5.1e-13 49.1 5.1 1.9 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KII92708.1 - 3.3e-10 40.3 1.6 5.6e-10 39.5 1.6 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KII92708.1 - 1.6e-07 31.6 0.2 3.7e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 DOMON domain DUF5336 PF17270.2 KII92708.1 - 0.029 14.0 0.6 0.98 9.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DUF2427 PF10348.9 KII92708.1 - 0.054 13.3 2.3 0.22 11.3 2.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) MaoC_dehydratas PF01575.19 KII92708.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 MaoC like domain MARVEL PF01284.23 KII92708.1 - 0.42 10.6 8.2 1.5 8.9 0.1 3.4 3 1 1 4 4 4 0 Membrane-associating domain API5 PF05918.11 KII92709.1 - 3.6e-20 72.3 0.2 5.1e-20 71.8 0.2 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.7 KII92709.1 - 0.0014 18.7 0.2 0.0036 17.4 0.2 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII92709.1 - 0.0036 17.6 0.7 0.25 11.8 0.1 3.2 3 1 0 3 3 3 1 HEAT repeats FUSC_2 PF13515.6 KII92710.1 - 5.2e-20 71.8 10.9 5.2e-20 71.8 10.9 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KII92710.1 - 4.8e-14 51.8 3.9 1.2e-11 43.9 2.6 2.9 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 KII92710.1 - 9.4e-09 34.6 10.0 7.9e-08 31.6 5.6 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 KII92710.1 - 1.3e-08 35.0 1.9 5.2e-08 33.0 0.0 2.5 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KII92710.1 - 1.1e-05 24.6 4.1 0.052 12.6 1.1 2.5 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS Asp PF00026.23 KII92711.1 - 2.9e-66 224.0 2.5 3.7e-66 223.7 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII92711.1 - 6.9e-12 46.0 14.6 8.9e-12 45.6 3.8 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII92711.1 - 0.028 15.0 0.4 0.028 15.0 0.4 3.5 3 1 0 3 3 3 0 Aspartyl protease Fungal_trans PF04082.18 KII92712.1 - 1.6e-12 47.0 0.2 3.6e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92712.1 - 1.7e-07 31.2 13.5 3.3e-07 30.3 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain stn_TNFRSF12A PF12191.8 KII92713.1 - 0.00016 21.9 0.1 0.00018 21.8 0.1 1.1 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TilS_C PF11734.8 KII92713.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.3 1 1 0 1 1 1 0 TilS substrate C-terminal domain Pkinase PF00069.25 KII92714.1 - 1.1e-70 238.0 0.0 1.6e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92714.1 - 1.3e-36 126.2 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KII92714.1 - 2.4e-16 59.8 0.2 4.8e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KII92714.1 - 1.3e-06 28.0 0.0 1.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 KII92714.1 - 2.3e-05 24.6 0.0 6.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KII92714.1 - 0.00025 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII92714.1 - 0.00098 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII92714.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII92714.1 - 0.0055 15.7 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Zn_clus PF00172.18 KII92715.1 - 7.5e-05 22.8 7.6 0.00015 21.8 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.12 KII92716.1 - 1.6e-50 170.9 0.0 1.8e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit S-methyl_trans PF02574.16 KII92717.1 - 4.1e-55 187.5 0.0 4.9e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ribosomal_S2 PF00318.20 KII92718.1 - 5.5e-29 101.0 0.2 2.8e-15 56.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KII92718.1 - 2.1e-08 35.4 10.5 3.7e-08 34.6 10.5 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Lipase_3 PF01764.25 KII92719.1 - 6.9e-32 110.3 0.0 1.2e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KII92719.1 - 0.015 14.6 0.2 0.036 13.3 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KII92719.1 - 0.095 12.3 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 KII92719.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KII92720.1 - 1.2e-27 96.5 0.0 1.7e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII92720.1 - 0.076 13.6 0.2 0.091 13.3 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acyltransferase PF01553.21 KII92721.1 - 5.2e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase CobD_Cbib PF03186.13 KII92721.1 - 0.028 13.7 1.2 0.046 12.9 1.2 1.3 1 0 0 1 1 1 0 CobD/Cbib protein E1-E2_ATPase PF00122.20 KII92722.1 - 4.9e-38 130.5 2.1 2.2e-35 121.8 0.6 3.1 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KII92722.1 - 5.3e-19 69.4 0.0 1.4e-18 68.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KII92722.1 - 7.9e-10 38.3 0.0 1.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII92722.1 - 0.00036 20.4 0.1 0.0034 17.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KII92722.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase YrvL PF14184.6 KII92722.1 - 2.9 8.0 15.1 0.021 14.9 6.0 2.0 2 0 0 2 2 2 0 Regulatory protein YrvL PP2C PF00481.21 KII92724.1 - 5.1e-43 147.6 0.0 8.4e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KII92724.1 - 1.4e-39 133.7 55.3 6.2e-11 41.9 8.9 11.6 6 2 9 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 KII92724.1 - 1.5e-37 126.9 63.9 4.8e-06 26.8 0.1 12.2 7 2 6 14 14 14 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KII92724.1 - 1.7e-26 93.0 0.0 3.5e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KII92724.1 - 0.0023 17.5 22.9 0.25 10.8 2.2 5.3 2 2 3 5 5 5 4 Leucine-rich repeat Mg_trans_NIPA PF05653.14 KII92725.1 - 9.2e-82 274.5 32.3 1.2e-81 274.0 32.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KII92725.1 - 6.8e-07 29.5 8.5 6.8e-07 29.5 8.5 3.4 3 1 0 3 3 3 2 EamA-like transporter family Tmemb_55A PF09788.9 KII92725.1 - 0.77 8.8 3.0 2.3 7.2 3.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 55A GST_N_4 PF17172.4 KII92726.1 - 8e-25 87.5 0.0 1.2e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KII92726.1 - 1.4e-09 38.4 0.0 2.1e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 KII92726.1 - 2.4e-06 27.5 0.0 6.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KII92726.1 - 8.6e-06 25.5 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KII92726.1 - 0.0003 20.9 0.0 0.00056 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KII92726.1 - 0.0083 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Rad9 PF04139.13 KII92728.1 - 5.1e-47 160.4 0.0 6.3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 ATP-sulfurylase PF01747.17 KII92729.1 - 1.3e-86 289.5 0.3 1.8e-86 289.0 0.3 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KII92729.1 - 3.9e-54 182.8 0.0 5.6e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KII92729.1 - 3.1e-53 179.7 0.0 5.4e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.10 KII92729.1 - 0.061 12.8 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 KII92729.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ERO1 PF04137.15 KII92731.1 - 3e-127 424.7 0.0 3.5e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Flu_M2 PF00599.17 KII92732.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ILVD_EDD PF00920.21 KII92733.1 - 7.3e-204 678.2 0.0 8.4e-204 678.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 KII92734.1 - 7.4e-16 57.2 0.5 0.00086 19.0 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII92734.1 - 6e-14 51.0 3.2 0.0044 17.0 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII92734.1 - 2.6e-09 36.5 0.1 0.1 12.9 0.0 4.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII92734.1 - 1.5e-08 35.1 3.6 9.1e-06 26.2 0.1 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII92734.1 - 3e-08 33.8 7.4 0.012 16.4 0.0 5.7 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII92734.1 - 1.3e-06 28.0 1.9 0.0019 17.8 0.1 4.2 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.6 KII92734.1 - 2.8e-05 24.3 11.0 0.036 14.4 0.6 4.8 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII92734.1 - 0.0001 22.8 5.3 0.36 11.4 0.4 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII92734.1 - 0.00012 21.8 5.6 7.2 6.9 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII92734.1 - 0.00033 20.8 0.8 3.1 8.4 0.0 4.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII92734.1 - 0.0017 18.9 0.5 2.3 9.0 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KII92734.1 - 0.002 17.6 0.0 0.05 13.0 0.0 2.8 2 1 1 3 3 3 1 Coatomer epsilon subunit ANAPC3 PF12895.7 KII92734.1 - 0.017 15.3 0.2 0.081 13.2 0.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KII92734.1 - 0.018 14.9 5.1 7.8 6.5 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KII92734.1 - 0.023 13.9 3.3 0.047 12.9 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat LprI PF07007.12 KII92734.1 - 0.59 10.8 3.6 0.78 10.4 0.1 2.8 2 1 0 2 2 2 0 Lysozyme inhibitor LprI HlyIII PF03006.20 KII92735.1 - 9.6e-33 113.8 21.1 1.4e-32 113.2 21.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-DISM_7TM PF07695.11 KII92735.1 - 0.027 14.3 15.6 0.6 10.0 0.3 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF1129 PF06570.11 KII92735.1 - 0.034 13.6 0.7 0.068 12.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC2_membrane_5 PF13346.6 KII92735.1 - 6.5 6.3 13.7 0.19 11.3 7.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Pept_tRNA_hydro PF01195.19 KII92736.1 - 7.2e-31 107.4 0.0 8.2e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_hydro_92 PF07971.12 KII92737.1 - 8.9e-123 410.6 1.1 1.1e-122 410.3 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KII92737.1 - 8.3e-52 176.4 0.4 1.4e-51 175.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain IF-2B PF01008.17 KII92738.1 - 1.4e-60 204.9 0.0 1.7e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SLC3A2_N PF16028.5 KII92739.1 - 0.013 15.0 0.9 0.017 14.6 0.9 1.2 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Pox_A51 PF04948.13 KII92739.1 - 0.017 14.0 0.2 0.02 13.8 0.2 1.0 1 0 0 1 1 1 0 Poxvirus A51 protein Zn_clus PF00172.18 KII92740.1 - 0.00023 21.2 10.8 0.00037 20.5 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KII92740.1 - 0.0098 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold MGC-24 PF05283.11 KII92740.1 - 1.4 9.3 4.8 0.28 11.6 1.0 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PRA1 PF03208.19 KII92742.1 - 2.7e-37 127.6 0.1 3.1e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein MPS-4 PF17523.2 KII92742.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF3981 PF13139.6 KII92742.1 - 0.14 12.5 0.7 0.24 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) TPR_1 PF00515.28 KII92743.1 - 5.3e-21 73.5 5.0 0.00021 21.0 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KII92743.1 - 2.4e-17 61.6 11.5 0.0011 18.9 0.0 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KII92743.1 - 4.4e-16 58.3 1.1 5.6e-05 22.7 0.7 4.7 3 1 1 4 4 4 4 TPR repeat TPR_17 PF13431.6 KII92743.1 - 3.7e-15 55.1 6.7 0.04 14.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KII92743.1 - 1.1e-14 53.9 12.6 0.0011 19.6 0.2 6.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KII92743.1 - 8e-14 50.6 2.1 0.026 14.7 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KII92743.1 - 2.3e-11 44.1 12.2 1.5e-05 25.4 0.8 4.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KII92743.1 - 4.2e-11 43.0 7.0 0.00053 20.2 2.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KII92743.1 - 5.4e-09 36.6 14.4 8e-06 26.4 1.7 4.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.6 KII92743.1 - 4.1e-08 33.4 5.6 0.079 13.3 0.1 5.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KII92743.1 - 7.9e-08 32.3 6.4 0.0033 17.6 1.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KII92743.1 - 0.00021 21.4 2.7 0.0062 16.7 0.9 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KII92743.1 - 0.0011 18.9 10.0 2.3 8.4 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII92743.1 - 0.0016 18.9 3.5 22 5.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KII92743.1 - 0.017 14.3 4.6 1.5 7.9 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 KII92743.1 - 0.074 12.0 0.2 0.18 10.8 0.1 1.7 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 KII92743.1 - 0.1 12.7 5.4 6.6 6.9 0.2 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KII92743.1 - 0.29 11.1 15.1 2.9 7.9 1.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KII92744.1 - 1.2e-10 41.2 19.3 0.0011 19.3 0.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII92744.1 - 5.8e-06 26.7 17.3 0.04 14.8 0.3 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII92744.1 - 4.2e-05 23.4 3.9 0.048 13.7 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII92744.1 - 8.1e-05 22.9 0.1 8.1e-05 22.9 0.1 3.7 4 0 0 4 4 4 1 Zinc-finger double domain FOXP-CC PF16159.5 KII92744.1 - 0.023 15.3 12.1 0.14 12.8 5.1 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KII92744.1 - 0.16 12.1 1.6 4.9 7.3 0.0 2.7 1 1 2 3 3 3 0 Aberrant zinc-finger zf-Di19 PF05605.12 KII92744.1 - 5.9 7.3 7.1 50 4.3 4.1 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KII92744.1 - 8.6 6.9 10.7 6.1 7.4 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Abhydrolase_3 PF07859.13 KII92745.1 - 1.6e-29 103.3 0.0 4.7e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII92745.1 - 0.015 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase ADH_zinc_N PF00107.26 KII92746.1 - 1.2e-09 38.3 0.0 2.8e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII92746.1 - 3.2e-07 30.2 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII92746.1 - 1.4e-06 29.4 0.2 4.6e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1075 PF06388.11 KII92746.1 - 0.072 13.1 0.0 8.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) zf-MYND PF01753.18 KII92747.1 - 1.5e-10 41.0 17.2 2.9e-10 40.1 17.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII92747.1 - 0.62 10.4 11.3 2 8.8 11.3 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 KII92747.1 - 2.8 8.4 10.2 5.2 7.5 10.2 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal RabGAP-TBC PF00566.18 KII92748.1 - 5.8e-53 179.7 0.1 7.9e-53 179.3 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 KII92748.1 - 0.033 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 NUP50 PF08911.11 KII92749.1 - 1.2e-15 58.0 0.5 1.2e-15 58.0 0.5 7.6 3 1 1 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 KII92749.1 - 6.2e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Ank PF00023.30 KII92750.1 - 3e-10 40.1 0.6 4.9e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KII92750.1 - 3.3e-10 40.4 0.1 5.9e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII92750.1 - 8.3e-09 35.8 0.3 2.6e-08 34.3 0.3 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII92750.1 - 1e-08 35.3 0.3 1.1e-07 32.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 KII92750.1 - 1e-08 35.1 0.3 3e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.6 KII92750.1 - 1.4e-08 34.3 0.1 0.0049 17.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat PARP PF00644.20 KII92751.1 - 1.5e-14 54.1 1.4 2.5e-11 43.5 0.5 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain RPAP2_Rtr1 PF04181.13 KII92751.1 - 0.0018 18.6 23.0 0.61 10.4 0.9 4.4 4 0 0 4 4 4 3 Rtr1/RPAP2 family zf-HIT PF04438.16 KII92751.1 - 0.012 15.4 2.0 0.012 15.4 2.0 5.2 5 1 0 5 5 5 0 HIT zinc finger Methyltransf_25 PF13649.6 KII92752.1 - 7.3e-07 29.8 0.0 2.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII92752.1 - 1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 KII92752.1 - 1.4e-06 28.8 0.1 3.6e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 KII92752.1 - 4.4e-06 26.3 0.0 9.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KII92752.1 - 0.0043 16.5 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KII92752.1 - 0.0044 16.7 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KII92752.1 - 0.0079 16.1 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII92752.1 - 0.042 14.6 0.0 0.17 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KII92752.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 KII92752.1 - 0.21 10.8 0.0 0.41 9.9 0.0 1.4 2 0 0 2 2 2 0 N-6 DNA Methylase Herpes_UL46 PF03387.14 KII92752.1 - 0.23 10.1 1.9 0.69 8.6 0.2 2.0 2 0 0 2 2 2 0 Herpesvirus UL46 protein zf-MYND PF01753.18 KII92753.1 - 1.3e-10 41.2 14.3 2.3e-10 40.4 14.3 1.5 1 0 0 1 1 1 1 MYND finger HicA_toxin PF07927.12 KII92754.1 - 2.6e-08 33.8 0.0 5.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, PTPRCAP PF15713.5 KII92754.1 - 4.1 7.7 16.8 6.7 7.0 1.3 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated eIF-3c_N PF05470.12 KII92754.1 - 7.3 4.8 7.1 14 3.8 7.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2207 PF09972.9 KII92755.1 - 0.0018 17.1 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) CE2_N PF17996.1 KII92755.1 - 0.0039 17.2 0.1 3.7 7.6 0.0 2.6 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Mid2 PF04478.12 KII92755.1 - 0.0093 15.8 0.1 0.079 12.8 0.0 2.4 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 KII92755.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.12 KII92755.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family PTP_tm PF18861.1 KII92755.1 - 0.084 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J BatD PF13584.6 KII92755.1 - 0.084 11.7 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Oxygen tolerance DUF3185 PF11381.8 KII92755.1 - 0.14 12.2 0.9 0.64 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Orf78 PF06024.12 KII92755.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 KII92755.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless SLATT_3 PF18184.1 KII92756.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 DUF1673 PF07895.11 KII92756.1 - 2.6 7.7 7.8 0.051 13.3 1.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) ATP_transf PF09830.9 KII92757.1 - 2.1e-22 79.0 0.0 6e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase DUF4922 PF16269.5 KII92757.1 - 0.00027 20.8 0.1 0.0025 17.6 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 KII92757.1 - 0.034 14.9 0.3 0.7 10.7 0.0 2.5 2 0 0 2 2 2 0 HIT domain p450 PF00067.22 KII92759.1 - 1e-78 265.2 0.0 1.3e-78 264.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KII92759.1 - 2.1e-26 92.9 0.0 3.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KII92759.1 - 1.8e-19 70.4 0.0 4.4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KII92759.1 - 6e-10 39.7 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2492 PF10678.9 KII92759.1 - 0.2 11.9 0.0 0.54 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) F-box-like PF12937.7 KII92760.1 - 3e-08 33.4 0.1 8.1e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII92760.1 - 0.00057 19.7 1.7 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain RNase_H2-Ydr279 PF09468.10 KII92761.1 - 1e-20 74.5 0.0 2.3e-20 73.4 0.0 1.6 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KII92761.1 - 2e-15 56.8 0.0 5e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Slu7 PF11708.8 KII92763.1 - 4e-107 358.0 16.1 4e-107 358.0 16.1 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KII92763.1 - 0.15 11.9 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3128 PF11326.8 KII92763.1 - 0.5 10.8 2.7 1.1 9.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) SNF2_N PF00176.23 KII92764.1 - 8.5e-61 205.6 0.4 1.6e-60 204.7 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KII92764.1 - 1.4e-26 92.8 0.8 1.1e-24 86.7 0.6 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KII92764.1 - 1.3e-19 70.6 0.0 3.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 KII92764.1 - 1.5e-19 69.6 8.0 6e-16 58.1 0.2 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KII92764.1 - 1.8e-09 37.8 0.0 8.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 KII92764.1 - 2.9e-08 34.0 1.8 2.9e-08 34.0 1.8 4.2 3 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 ERCC3_RAD25_C PF16203.5 KII92764.1 - 4.3e-05 22.9 0.7 0.00011 21.5 0.7 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CDH1_2_SANT_HL1 PF18375.1 KII92764.1 - 0.0031 18.1 0.2 0.0031 18.1 0.2 2.8 3 0 0 3 3 2 1 CDH1/2 SANT-Helical linker 1 DUF1357 PF07094.11 KII92764.1 - 0.025 14.6 0.2 0.062 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Myb_DNA-binding PF00249.31 KII92764.1 - 0.026 14.7 0.0 0.085 13.1 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain CHDCT2 PF08074.11 KII92764.1 - 2.2 8.4 5.3 3 8.0 0.0 3.7 4 1 0 4 4 4 0 CHDCT2 (NUC038) domain DUF1771 PF08590.10 KII92765.1 - 8.4e-06 26.1 7.0 1.7e-05 25.1 7.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Melibiase_2 PF16499.5 KII92767.1 - 6.1e-51 173.3 2.3 2.9e-50 171.0 2.3 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KII92767.1 - 3.1e-12 46.4 0.0 2.1e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain CBM_1 PF00734.18 KII92767.1 - 2.7e-11 43.2 13.3 2.7e-11 43.2 13.3 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Melibiase PF02065.18 KII92767.1 - 1.5e-05 24.2 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Melibiase 2OG-FeII_Oxy_2 PF13532.6 KII92770.1 - 8.2e-20 71.8 0.0 2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.16 KII92771.1 - 1.7e-17 63.1 0.1 2.4e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain APG6 PF04111.12 KII92772.1 - 1.4e-71 240.2 0.0 2.2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KII92772.1 - 3.6e-30 105.2 20.9 7e-30 104.3 20.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF2031 PF09592.10 KII92772.1 - 0.096 12.2 3.7 0.18 11.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) FtsL PF04999.13 KII92772.1 - 0.23 11.5 2.6 0.49 10.4 2.6 1.5 1 0 0 1 1 1 0 Cell division protein FtsL GCS PF03074.16 KII92773.1 - 1.2e-174 580.9 0.0 1.5e-174 580.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 KII92773.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Peptidase_C14 PF00656.22 KII92774.1 - 2.3e-23 83.4 0.0 3.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain FA_desaturase PF00487.24 KII92775.1 - 6.7e-18 65.4 21.2 6.7e-18 65.4 21.2 1.7 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII92775.1 - 8.7e-14 51.4 0.0 2.4e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 KII92777.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HTH_30 PF13556.6 KII92778.1 - 0.0012 18.6 2.2 0.0038 17.0 0.5 2.5 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 KII92778.1 - 0.088 12.9 1.4 0.17 12.0 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain AT_hook PF02178.19 KII92778.1 - 0.097 12.6 1.7 0.17 11.9 1.7 1.4 1 0 0 1 1 1 0 AT hook motif HTH_10 PF04967.12 KII92778.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_11 PF08279.12 KII92778.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 2 0 HTH domain DUF3678 PF12435.8 KII92780.1 - 2.2 7.7 6.7 6.2 6.3 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) gag-asp_proteas PF13975.6 KII92782.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SWIRM-assoc_2 PF16496.5 KII92783.1 - 0.17 10.7 2.2 0.26 10.1 2.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Apt1 PF10351.9 KII92783.1 - 5.4 5.8 5.4 6 5.6 5.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF241 PF03087.14 KII92785.1 - 0.03 14.2 0.1 0.043 13.6 0.1 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Lipoprotein_20 PF13942.6 KII92785.1 - 0.035 14.0 0.3 0.051 13.5 0.3 1.1 1 0 0 1 1 1 0 YfhG lipoprotein CN_hydrolase PF00795.22 KII92786.1 - 1.3e-42 146.0 0.0 1.7e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1525 PF07511.11 KII92788.1 - 0.083 13.0 0.5 0.46 10.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1525) IMS PF00817.20 KII92789.1 - 3.3e-42 144.0 0.0 7.1e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KII92789.1 - 1.8e-15 57.6 0.0 6.4e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KII92789.1 - 0.09 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif RraA-like PF03737.15 KII92790.1 - 2e-35 122.2 0.0 2.5e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA PA PF02225.22 KII92790.1 - 0.093 12.8 0.6 0.16 12.0 0.5 1.6 1 1 0 1 1 1 0 PA domain VanZ PF04892.12 KII92791.1 - 8.1e-06 26.5 5.2 1.5e-05 25.6 5.2 1.5 1 1 0 1 1 1 1 VanZ like family Phage_holin_3_3 PF16083.5 KII92791.1 - 0.0092 16.1 1.5 0.021 14.9 1.5 1.6 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Virul_fac_BrkB PF03631.15 KII92791.1 - 0.014 15.0 1.2 0.018 14.7 1.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Peptidase_U4 PF03419.13 KII92791.1 - 0.5 9.6 4.1 1.6 8.0 4.1 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF2304 PF10066.9 KII92791.1 - 1.1 9.6 4.8 2.3 8.5 4.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) zf-DNL PF05180.12 KII92792.1 - 2.7e-28 97.7 0.1 3.8e-28 97.2 0.1 1.1 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KII92792.1 - 0.079 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Asparaginase_2 PF01112.18 KII92793.1 - 4.9e-53 180.2 0.4 8e-53 179.4 0.1 1.4 2 0 0 2 2 2 1 Asparaginase STE2 PF02116.15 KII92794.1 - 0.0067 15.8 15.9 0.026 13.8 15.8 2.0 1 1 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR MRP-L27 PF09809.9 KII92794.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF4131 PF13567.6 KII92794.1 - 0.48 10.0 4.2 0.74 9.4 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3087 PF11286.8 KII92794.1 - 1 8.8 10.1 0.74 9.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Tfb4 PF03850.14 KII92795.1 - 2.4e-84 283.1 0.2 2.9e-84 282.8 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Orthopox_B11R PF07033.11 KII92795.1 - 0.18 11.6 0.3 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus B11R protein zf-met2 PF12907.7 KII92795.1 - 2.5 8.3 10.7 5.6 7.2 0.0 3.5 3 0 0 3 3 3 0 Zinc-binding Pyrid_ox_like PF16242.5 KII92798.1 - 1.1e-28 99.8 0.0 1.6e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KII92798.1 - 1.3e-11 44.5 0.1 1e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase TRI5 PF06330.11 KII92799.1 - 8.1e-24 84.1 0.0 1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) adh_short PF00106.25 KII92800.1 - 1.4e-32 112.8 0.0 1.9e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII92800.1 - 3.4e-28 98.8 0.1 4.1e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92800.1 - 1.6e-11 44.5 0.0 2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII92800.1 - 0.0003 20.7 2.5 0.0006 19.8 2.6 1.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII92800.1 - 0.0031 17.0 0.0 0.0084 15.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KII92800.1 - 0.029 14.3 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ACP_syn_III PF08545.10 KII92800.1 - 0.09 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MoCF_biosynth PF00994.24 KII92800.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 Probable molybdopterin binding domain SdpI PF13630.6 KII92801.1 - 3.5 7.8 6.0 1.9 8.6 1.5 3.0 3 1 0 3 3 3 0 SdpI/YhfL protein family zf-SNAP50_C PF12251.8 KII92802.1 - 3.2e-29 102.1 0.0 5.2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C3HC4_2 PF13923.6 KII92803.1 - 4.2e-07 29.7 13.2 4.2e-07 29.7 13.2 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII92803.1 - 6.1e-06 26.5 13.1 6.1e-06 26.5 13.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KII92803.1 - 3.3e-05 23.8 14.1 3.3e-05 23.8 14.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-TRAF PF02176.18 KII92803.1 - 0.00012 22.7 19.3 0.001 19.7 2.6 3.6 1 1 4 5 5 5 4 TRAF-type zinc finger zf-Nse PF11789.8 KII92803.1 - 0.00014 21.6 7.8 0.00014 21.6 7.8 2.6 2 1 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-TRAF_2 PF15965.5 KII92803.1 - 0.00039 20.8 3.6 0.00039 20.8 3.6 3.1 1 1 1 2 2 2 1 TRAF-like zinc-finger zf-C3HC4 PF00097.25 KII92803.1 - 0.00042 20.1 13.1 0.00042 20.1 13.1 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII92803.1 - 0.00079 19.2 9.9 0.00079 19.2 9.9 2.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII92803.1 - 0.0075 16.2 11.1 0.0075 16.2 11.1 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Sina PF03145.16 KII92803.1 - 0.055 13.4 11.1 0.066 13.2 1.2 2.8 1 1 2 3 3 3 0 Seven in absentia protein family Homeodomain PF00046.29 KII92804.1 - 8.4e-16 57.6 0.0 1.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 KII92806.1 - 1.5e-45 155.6 0.0 1.9e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92806.1 - 5.4e-29 101.3 0.0 7.7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DPBB_1 PF03330.18 KII92808.1 - 8e-05 22.8 0.1 0.00015 22.0 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Aldolase_II PF00596.21 KII92809.1 - 3.5e-36 124.9 0.0 4.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Bromodomain PF00439.25 KII92810.1 - 1e-23 83.2 0.1 1.9e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KII92810.1 - 5e-06 26.7 0.0 9.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII92810.1 - 6.1e-05 23.0 0.2 0.00015 21.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII92810.1 - 0.0009 19.6 0.3 0.0017 18.7 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 KII92812.1 - 5.4e-46 156.2 0.0 7.4e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII92812.1 - 3.2e-19 68.9 0.0 4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII92812.1 - 4.9e-06 26.8 0.0 1.3e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII92812.1 - 0.0068 17.0 0.0 0.034 14.7 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF3884 PF13024.6 KII92812.1 - 0.023 14.2 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) Shikimate_DH PF01488.20 KII92812.1 - 0.067 13.3 0.0 0.5 10.4 0.0 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 KII92812.1 - 0.11 13.4 0.0 0.25 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BAG PF02179.16 KII92813.1 - 6.7e-17 61.7 0.0 9.7e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KII92813.1 - 1.3e-06 28.1 0.0 6.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family PHD PF00628.29 KII92815.1 - 0.0029 17.5 0.8 0.013 15.3 0.3 2.0 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.11 KII92815.1 - 0.077 13.3 3.2 0.16 12.3 3.2 1.8 1 1 0 1 1 1 0 RING-like domain Pkinase PF00069.25 KII92816.1 - 8.9e-54 182.6 0.0 1.1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92816.1 - 1e-34 120.0 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII92816.1 - 1e-05 25.1 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII92816.1 - 0.011 14.6 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KII92816.1 - 0.014 15.3 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII92816.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1 PF00133.22 KII92817.1 - 3.6e-225 748.8 0.0 3.8e-224 745.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KII92817.1 - 4.6e-28 98.1 0.1 1e-27 97.0 0.0 1.6 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KII92817.1 - 1.4e-12 47.1 0.6 6.1e-05 21.9 0.1 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KII92817.1 - 0.022 14.1 0.0 0.096 12.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.8 KII92818.1 - 9.3e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII92818.1 - 5.8e-06 26.5 0.2 9.5e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KII92818.1 - 0.00076 19.5 1.4 0.00076 19.5 1.4 2.0 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KII92818.1 - 0.0014 18.7 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger Orbi_VP6 PF01516.16 KII92818.1 - 0.0075 15.8 2.4 0.0075 15.8 2.4 1.7 2 0 0 2 2 2 1 Orbivirus helicase VP6 zf-C2H2 PF00096.26 KII92818.1 - 0.036 14.5 0.3 0.062 13.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type CxC7 PF18866.1 KII92818.1 - 0.056 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases zf-C2H2_4 PF13894.6 KII92818.1 - 0.12 13.3 0.1 0.23 12.4 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1490 PF07371.12 KII92818.1 - 0.32 11.1 3.9 0.73 9.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Atg14 PF10186.9 KII92818.1 - 4 6.4 11.3 0.11 11.6 0.5 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spore_III_AF PF09581.10 KII92818.1 - 7.8 6.5 10.0 1.5 8.8 1.6 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) EXS PF03124.14 KII92819.1 - 4.1e-102 341.9 9.7 4.6e-102 341.7 9.7 1.0 1 0 0 1 1 1 1 EXS family DUF3267 PF11667.8 KII92820.1 - 0.16 12.2 6.5 1.2 9.4 0.8 2.6 3 0 0 3 3 3 0 Putative zincin peptidase CytochromB561_N PF09786.9 KII92820.1 - 1.2 8.1 4.5 1.5 7.7 4.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MOZ_SAS PF01853.18 KII92821.1 - 1.3e-79 266.0 0.3 2.1e-79 265.3 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KII92821.1 - 1.5e-22 78.9 0.7 3.1e-22 77.9 0.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KII92821.1 - 2.4e-16 59.3 0.1 5.9e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KII92821.1 - 0.0022 18.4 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII92821.1 - 0.026 14.8 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Plus-3 PF03126.18 KII92821.1 - 0.051 14.1 0.0 8.3 7.0 0.0 3.0 3 0 0 3 3 3 0 Plus-3 domain Acetyltransf_16 PF05301.11 KII92821.1 - 0.062 13.1 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase, Mec-17 FYDLN_acid PF09538.10 KII92821.1 - 1.2 9.8 13.1 3.1 8.5 13.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.6 KII92821.1 - 3.9 8.6 5.0 1.9 9.6 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger LAG1-DNAbind PF09271.11 KII92822.1 - 4.2e-50 170.3 0.0 6.5e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KII92822.1 - 1.6e-19 70.6 0.0 3.8e-18 66.2 0.0 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain zf-GRF PF06839.12 KII92825.1 - 2.6e-08 33.8 2.9 4.6e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF4200 PF13863.6 KII92825.1 - 0.01 16.2 1.0 0.018 15.4 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Herpes_BLRF2 PF05812.12 KII92825.1 - 0.097 12.8 1.6 5.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF724 PF05266.14 KII92825.1 - 0.11 12.3 0.7 0.18 11.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 KII92825.1 - 0.53 10.4 5.2 1.6 8.9 5.2 1.8 1 1 0 1 1 1 0 bZIP transcription factor PAC4 PF16093.5 KII92826.1 - 7.6e-24 83.7 0.1 9.7e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Pkinase PF00069.25 KII92829.1 - 3.4e-50 170.9 0.1 7e-50 169.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92829.1 - 3.9e-22 78.8 0.0 7.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII92829.1 - 0.00018 21.5 0.1 0.00018 21.5 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII92829.1 - 0.00048 19.8 0.6 0.0011 18.6 0.6 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KII92829.1 - 0.02 14.5 0.5 0.085 12.4 0.5 2.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.12 KII92830.1 - 6.2e-56 189.4 0.0 7e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 KII92830.1 - 0.0031 17.9 0.1 0.018 15.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF5596 PF18082.1 KII92830.1 - 0.022 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) DUF2608 PF11019.8 KII92830.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) BSD PF03909.17 KII92831.1 - 8.1e-18 64.2 4.9 1e-13 51.1 0.1 2.9 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KII92831.1 - 1.6e-17 63.6 0.0 3.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF3446 PF11928.8 KII92831.1 - 0.13 12.5 2.6 0.33 11.3 2.6 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain CASP_C PF08172.12 KII92832.1 - 4e-78 262.3 1.3 4e-78 262.3 1.3 3.7 2 1 1 3 3 3 1 CASP C terminal DUF1510 PF07423.11 KII92832.1 - 0.076 13.2 1.2 0.27 11.4 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) ATG16 PF08614.11 KII92832.1 - 3.4 7.8 69.4 0.74 10.0 13.4 5.3 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF3138 PF11336.8 KII92832.1 - 8.1 4.9 9.8 0.35 9.4 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Ribosomal_S9 PF00380.19 KII92833.1 - 2.9e-44 150.4 0.2 4.4e-44 149.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.11 KII92834.1 - 2.6e-19 69.1 9.7 2.6e-19 69.1 9.7 7.9 5 3 4 9 9 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KII92834.1 - 3.8e-07 29.9 10.6 6.6e-07 29.1 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII92834.1 - 5e-06 26.3 12.4 9.5e-06 25.4 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII92834.1 - 1.5e-05 24.8 12.5 3.1e-05 23.9 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII92834.1 - 2.6e-05 24.0 13.2 4.8e-05 23.1 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII92834.1 - 5.8e-05 23.0 7.7 0.00011 22.1 7.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII92834.1 - 0.00032 21.0 11.4 0.00059 20.1 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KII92834.1 - 0.00069 19.4 8.3 0.0012 18.6 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KII92834.1 - 0.015 15.5 7.4 0.044 14.1 7.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KII92834.1 - 0.028 14.3 3.4 0.055 13.4 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 KII92834.1 - 0.056 13.5 5.4 0.15 12.1 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) WD40_alt PF14077.6 KII92834.1 - 0.31 11.0 4.1 6 6.8 0.1 4.4 5 0 0 5 5 5 0 Alternative WD40 repeat motif zf-C3HC4_4 PF15227.6 KII92834.1 - 0.33 11.1 7.6 0.68 10.1 7.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 KII92834.1 - 0.44 10.5 4.9 0.97 9.4 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LPP PF04728.13 KII92834.1 - 0.52 10.7 13.2 2.3 8.6 0.8 4.6 5 0 0 5 5 4 0 Lipoprotein leucine-zipper TRAF_BIRC3_bd PF16673.5 KII92834.1 - 0.56 10.0 16.8 0.36 10.7 0.4 5.3 5 1 1 6 6 6 0 TNF receptor-associated factor BIRC3 binding domain zf-RING_4 PF14570.6 KII92834.1 - 0.91 9.4 8.4 1.2 9.0 7.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4094 PF13334.6 KII92834.1 - 8.9 6.8 18.2 0.03 14.7 2.6 4.1 4 1 0 4 4 3 0 Domain of unknown function (DUF4094) Allantoicase PF03561.15 KII92835.1 - 7.3e-91 301.6 0.0 5.6e-46 156.1 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 KII92835.1 - 1.9e-48 164.7 0.0 2.6e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase LRR_RI_capping PF18779.1 KII92835.1 - 0.023 14.3 2.2 0.038 13.6 0.3 2.0 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Olduvai PF06758.13 KII92835.1 - 0.18 12.1 1.0 0.3 11.4 0.1 1.7 2 0 0 2 2 2 0 Olduvai domain Smr PF01713.21 KII92836.1 - 0.0075 16.6 0.4 0.016 15.6 0.4 1.5 1 0 0 1 1 1 1 Smr domain Transformer PF06495.11 KII92836.1 - 0.11 12.6 1.1 0.13 12.4 1.1 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Ost4 PF10215.9 KII92837.1 - 0.12 12.2 0.3 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 Oligosaccaryltransferase Baculo_PEP_C PF04513.12 KII92838.1 - 0.15 12.1 21.0 0.26 11.4 0.8 4.2 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bax1-I PF01027.20 KII92839.1 - 4.5e-49 167.1 26.2 5.2e-49 166.9 26.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Relaxase PF03432.14 KII92840.1 - 0.009 15.6 2.1 14 5.2 0.0 3.1 3 0 0 3 3 3 3 Relaxase/Mobilisation nuclease domain FmrO PF07091.11 KII92841.1 - 0.0043 16.6 0.0 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ten1_2 PF15490.6 KII92841.1 - 0.083 12.6 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit SnAPC_2_like PF11035.8 KII92842.1 - 0.0094 16.1 0.3 0.013 15.6 0.3 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF4551 PF15087.6 KII92843.1 - 1.3 7.8 8.2 1.6 7.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 KII92843.1 - 2.6 6.5 4.4 2.9 6.4 4.4 1.1 1 0 0 1 1 1 0 Macoilin family FAM220 PF15487.6 KII92843.1 - 9.7 5.7 8.3 7.7 6.1 6.9 1.5 1 1 0 1 1 1 0 FAM220 family WD40 PF00400.32 KII92845.1 - 1.5e-24 85.7 13.3 3.6e-05 24.4 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII92845.1 - 3.8e-06 27.1 0.2 0.6 10.4 0.0 4.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 KII92845.1 - 0.0025 17.3 0.2 0.0076 15.7 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5046) Frtz PF11768.8 KII92845.1 - 0.0029 16.0 0.0 0.024 13.0 0.0 1.9 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 KII92845.1 - 0.0034 17.2 0.1 10 6.3 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat WD40_like PF17005.5 KII92845.1 - 0.0074 15.7 0.2 0.48 9.7 0.0 2.8 1 1 1 3 3 3 1 WD40-like domain SAVED PF18145.1 KII92845.1 - 0.032 14.0 0.1 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain Nup160 PF11715.8 KII92845.1 - 0.091 11.4 1.1 5.2 5.6 0.1 3.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 F-box-like PF12937.7 KII92846.1 - 5.9e-08 32.5 1.7 1.4e-07 31.3 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII92846.1 - 0.0095 15.8 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain LSM PF01423.22 KII92847.1 - 5.2e-15 54.9 0.2 6.7e-15 54.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII92847.1 - 0.029 14.5 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Snapin_Pallidin PF14712.6 KII92850.1 - 0.065 13.7 2.1 0.11 12.9 1.0 2.0 2 0 0 2 2 2 0 Snapin/Pallidin FapA PF03961.13 KII92850.1 - 0.24 10.0 0.6 0.34 9.5 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 KII92850.1 - 7.8 7.0 7.1 25 5.4 0.5 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DOCK_N PF16172.5 KII92851.1 - 1e-117 393.2 0.0 1.5e-117 392.7 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KII92851.1 - 7.6e-74 249.2 0.0 2.8e-73 247.4 0.0 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KII92851.1 - 3e-53 180.6 0.0 2.3e-52 177.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF1174 PF06671.11 KII92851.1 - 0.13 12.0 1.4 0.31 10.8 1.4 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1174) TYA PF01021.19 KII92852.1 - 0.037 14.4 0.3 0.046 14.0 0.2 1.3 1 1 0 1 1 1 0 TYA transposon protein Alpha_kinase PF02816.18 KII92855.1 - 3.2e-22 79.6 0.0 9.5e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Alpha-kinase family Mob1_phocein PF03637.17 KII92856.1 - 1.8e-25 89.9 0.1 2.7e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Med27 PF11571.8 KII92858.1 - 6.5e-13 48.8 0.5 2.1e-12 47.2 0.2 1.9 2 0 0 2 2 2 1 Mediator complex subunit 27 Ribosomal_L22 PF00237.19 KII92858.1 - 0.0047 17.1 0.1 0.006 16.8 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e TPR_16 PF13432.6 KII92859.1 - 2.4e-40 136.9 65.2 8.9e-10 39.1 4.6 14.3 12 3 3 16 16 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 KII92859.1 - 3.6e-36 120.4 31.1 0.00053 19.9 0.3 18.0 19 0 0 19 19 17 8 Tetratricopeptide repeat TPR_1 PF00515.28 KII92859.1 - 6e-36 120.8 10.5 0.00011 21.9 0.1 14.3 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.6 KII92859.1 - 1.2e-29 100.4 74.4 0.0014 19.3 0.1 19.4 11 8 11 23 23 19 7 Tetratricopeptide repeat TPR_19 PF14559.6 KII92859.1 - 4.4e-27 94.4 46.4 0.0045 17.5 0.0 14.8 12 5 3 15 15 15 9 Tetratricopeptide repeat TPR_8 PF13181.6 KII92859.1 - 1.8e-25 86.9 17.8 4.9e-05 23.2 0.1 14.2 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 KII92859.1 - 2.7e-21 74.9 15.8 0.015 15.0 0.0 13.9 15 1 1 16 16 15 6 TPR repeat TPR_9 PF13371.6 KII92859.1 - 6.6e-21 74.2 44.0 0.00049 20.2 0.1 11.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 KII92859.1 - 1.9e-20 72.9 42.9 0.00044 20.5 0.1 14.7 12 2 3 15 15 15 8 Tetratricopeptide repeat TPR_17 PF13431.6 KII92859.1 - 1.9e-16 59.1 18.4 0.0055 17.0 0.0 12.8 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 KII92859.1 - 1.4e-15 56.8 22.4 0.6 10.9 0.0 13.9 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 KII92859.1 - 5.4e-15 54.2 16.6 0.011 15.8 0.0 10.8 13 0 0 13 13 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KII92859.1 - 2.5e-11 43.6 3.2 0.047 13.9 0.0 8.8 7 3 2 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KII92859.1 - 0.00011 21.8 12.9 0.009 15.4 1.7 4.6 3 1 0 3 3 3 2 MalT-like TPR region NARP1 PF12569.8 KII92859.1 - 0.00019 20.5 1.4 0.73 8.7 0.0 4.3 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 KII92859.1 - 0.0007 19.6 0.1 6.9 6.8 0.1 4.5 3 1 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KII92859.1 - 0.00079 19.2 22.9 0.71 9.8 0.0 8.2 7 0 0 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KII92859.1 - 0.0037 16.0 7.9 0.0083 14.9 0.0 4.4 3 1 0 4 4 4 1 Protein kinase G tetratricopeptide repeat FAT PF02259.23 KII92859.1 - 0.0058 15.9 1.9 0.63 9.2 0.1 4.3 4 1 1 5 5 5 1 FAT domain Glyco_hyd_65N_2 PF14498.6 KII92859.1 - 0.032 14.1 0.1 0.091 12.6 0.1 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TPR_22 PF18833.1 KII92859.1 - 0.035 14.2 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 KII92859.1 - 0.035 13.8 1.6 14 5.3 0.1 4.2 4 1 0 4 4 3 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 KII92859.1 - 0.058 13.7 23.8 0.22 11.9 0.0 8.4 10 1 1 11 11 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KII92859.1 - 0.19 12.5 40.2 3.8 8.4 0.1 11.3 12 0 0 12 12 9 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KII92859.1 - 0.94 9.6 3.5 26 5.0 0.0 4.3 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 zf-CCHH PF10283.9 KII92860.1 - 0.051 13.6 1.5 0.14 12.2 1.5 1.7 1 0 0 1 1 1 0 PBZ domain U3snoRNP10 PF12397.8 KII92860.1 - 0.14 12.5 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 LETM1 PF07766.13 KII92861.1 - 1.6e-27 96.5 3.5 3e-15 56.3 0.2 2.3 3 0 0 3 3 3 2 LETM1-like protein Chitin_synth_2 PF03142.15 KII92862.1 - 1.7e-254 845.4 0.0 2.2e-254 845.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KII92862.1 - 3.5e-13 50.0 0.0 3.7e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KII92862.1 - 2.1e-12 47.4 8.6 2.7e-12 47.0 5.3 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KII92862.1 - 0.018 14.5 0.1 0.58 9.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Cyt-b5 PF00173.28 KII92862.1 - 0.019 15.1 0.0 0.25 11.5 0.0 2.6 2 1 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 KII92862.1 - 0.092 12.5 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DSPc PF00782.20 KII92865.1 - 2.6e-06 27.3 1.2 5.7e-06 26.2 0.2 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KII92865.1 - 0.00016 21.4 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KII92865.1 - 0.00029 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KII92865.1 - 0.02 15.0 0.1 0.046 13.8 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF3712 PF12505.8 KII92866.1 - 9.8e-111 365.1 46.0 4.2e-25 88.4 0.0 9.5 9 1 1 10 10 10 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KII92866.1 - 3.6e-10 40.3 28.1 0.0012 19.4 0.2 9.5 11 0 0 11 11 11 5 Late embryogenesis abundant protein GPI-anchored PF10342.9 KII92867.1 - 6.3e-09 36.5 0.2 7.9e-09 36.2 0.2 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII92867.1 - 0.0069 16.2 0.4 0.009 15.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SNARE PF05739.19 KII92868.1 - 1.6e-10 40.8 0.2 4.4e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KII92868.1 - 0.001 18.8 0.9 0.0017 18.1 0.9 1.4 1 0 0 1 1 1 1 Syntaxin Rossmann-like PF10727.9 KII92868.1 - 0.019 14.9 0.3 0.045 13.6 0.3 1.6 1 0 0 1 1 1 0 Rossmann-like domain Translin PF01997.16 KII92868.1 - 0.24 11.4 2.0 0.3 11.0 0.9 1.7 1 1 1 2 2 2 0 Translin family Striatin PF08232.12 KII92868.1 - 1.1 9.9 5.2 15 6.2 2.3 2.4 2 0 0 2 2 2 0 Striatin family WD40 PF00400.32 KII92869.1 - 1.1e-25 89.3 19.6 5.2e-10 39.7 0.2 7.8 8 0 0 8 8 6 3 WD domain, G-beta repeat NACHT PF05729.12 KII92869.1 - 1.7e-09 37.8 0.0 3.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KII92869.1 - 3.6e-07 30.4 0.4 0.054 13.8 0.0 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KII92869.1 - 1.5e-05 25.4 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 KII92869.1 - 4.9e-05 23.3 0.0 9.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.22 KII92869.1 - 0.00075 18.8 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Gmad1 PF10647.9 KII92869.1 - 0.0013 18.6 0.4 3 7.5 0.1 4.2 3 2 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain Sec7_N PF12783.7 KII92869.1 - 0.0044 16.9 1.7 0.0044 16.9 1.7 1.9 1 1 1 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal AAA PF00004.29 KII92869.1 - 0.0083 16.5 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KII92869.1 - 0.013 15.4 0.4 0.029 14.3 0.1 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 KII92869.1 - 0.014 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KII92869.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KII92869.1 - 0.023 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PD40 PF07676.12 KII92869.1 - 0.027 14.4 8.2 32 4.6 0.0 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KII92869.1 - 0.027 13.8 0.0 0.085 12.2 0.0 1.9 1 0 0 1 1 1 0 WD40-like domain AAA_14 PF13173.6 KII92869.1 - 0.036 14.1 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII92869.1 - 0.058 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KII92869.1 - 0.081 12.7 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KII92869.1 - 0.093 13.1 0.2 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KII92869.1 - 0.12 12.7 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 KII92869.1 - 0.13 12.3 0.0 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KII92869.1 - 0.16 11.6 0.2 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase IpaB_EvcA PF03278.13 KII92870.1 - 0.11 12.2 0.1 5.5 6.7 0.1 2.3 2 0 0 2 2 2 0 IpaB/EvcA family BTB PF00651.31 KII92874.1 - 0.0097 16.1 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Shisa PF13908.6 KII92875.1 - 8.1e-06 26.2 0.5 1.7e-05 25.2 0.0 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator GPR15L PF15854.5 KII92875.1 - 0.025 14.8 1.2 0.085 13.1 0.3 2.0 1 1 1 2 2 2 0 G-protein coupled receptor ligand 15 EphA2_TM PF14575.6 KII92875.1 - 0.17 12.7 0.0 0.36 11.7 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KII92875.1 - 0.34 11.6 6.3 3.6 8.3 6.3 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pro_isomerase PF00160.21 KII92877.1 - 2.2e-45 154.8 0.0 2.6e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 KII92878.1 - 1.7e-38 132.1 0.0 2.6e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KII92878.1 - 1.8e-18 66.5 0.2 3.6e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KII92878.1 - 1.6e-16 60.6 0.0 9.3e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII92878.1 - 0.0026 17.8 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PH_8 PF15409.6 KII92878.1 - 0.11 12.8 0.8 0.91 9.9 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short PF00106.25 KII92879.1 - 1.3e-19 70.5 0.0 2.9e-17 62.8 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII92879.1 - 1e-10 41.6 0.0 3.4e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92879.1 - 9.4e-06 25.7 0.1 2e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 KII92879.1 - 0.0022 17.7 0.0 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII92879.1 - 0.035 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MmgE_PrpD PF03972.14 KII92881.1 - 7e-156 519.2 0.0 8e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family adh_short PF00106.25 KII92882.1 - 4.5e-21 75.2 0.0 2.4e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII92882.1 - 2.9e-12 46.7 0.1 6.1e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92882.1 - 4.6e-05 23.4 0.2 0.00024 21.1 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 KII92882.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KII92883.1 - 9.4e-24 83.9 0.0 4.6e-19 68.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII92883.1 - 1.2e-12 47.9 0.0 1.2e-10 41.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92883.1 - 0.0003 20.8 0.0 0.00058 19.8 0.0 1.6 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KII92883.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 KII92884.1 - 1.2e-20 73.8 0.0 3.7e-18 65.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII92884.1 - 3.3e-11 43.2 0.0 1.6e-10 40.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII92884.1 - 7.3e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII92884.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII92884.1 - 0.029 14.4 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Melibiase_2_C PF17450.2 KII92884.1 - 0.13 12.5 0.0 0.81 10.0 0.0 2.2 1 1 1 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain Pkinase PF00069.25 KII92885.1 - 1.7e-60 204.7 0.0 2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII92885.1 - 4.1e-35 121.3 0.0 5.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII92885.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII92885.1 - 0.0017 17.7 0.0 0.007 15.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KII92885.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_N PF00134.23 KII92886.1 - 0.048 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain LIAS_N PF16881.5 KII92886.1 - 0.092 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family SLT PF01464.20 KII92887.1 - 1.1e-11 44.4 0.0 1.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain TMEM40 PF15817.5 KII92887.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family Asp PF00026.23 KII92889.1 - 2.9e-50 171.5 9.4 6.4e-50 170.4 9.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII92889.1 - 3.5e-10 40.4 1.8 2e-06 28.2 0.4 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII92889.1 - 0.011 16.3 2.1 8 7.2 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Gln-synt_N PF03951.19 KII92889.1 - 0.05 13.3 0.7 0.33 10.7 0.0 2.5 3 1 1 4 4 4 0 Glutamine synthetase, beta-Grasp domain TAXi_C PF14541.6 KII92889.1 - 0.092 12.5 0.0 4.1 7.2 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Lipocalin_4 PF13648.6 KII92889.1 - 0.32 12.0 4.2 0.45 11.5 0.3 2.5 2 0 0 2 2 2 0 Lipocalin-like domain Fungal_trans_2 PF11951.8 KII92890.1 - 4.5e-44 150.8 0.4 5.7e-44 150.5 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII92890.1 - 4.9e-07 29.8 8.5 4.9e-07 29.8 8.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PknG_rubred PF16919.5 KII92890.1 - 0.0097 16.1 0.3 0.02 15.0 0.3 1.5 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain PPP5 PF08321.12 KII92892.1 - 4.3e-28 97.4 0.0 6.5e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KII92892.1 - 7.1e-26 92.0 0.0 1.1e-25 91.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KII92892.1 - 0.028 14.2 0.2 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AbrB_C PF18277.1 KII92892.1 - 0.14 11.8 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 AbrB C-terminal domain KH_1 PF00013.29 KII92894.1 - 2.9e-86 283.3 25.5 2.1e-13 49.9 0.4 14.0 13 2 0 13 13 13 11 KH domain KH_2 PF07650.17 KII92894.1 - 4.5e-10 39.2 13.6 0.11 12.4 0.0 7.0 6 0 0 6 6 6 5 KH domain SLS PF14611.6 KII92894.1 - 6.5e-07 29.4 22.2 0.031 14.1 0.6 7.4 5 2 1 6 6 6 4 Mitochondrial inner-membrane-bound regulator DUF4974 PF16344.5 KII92894.1 - 0.0006 19.8 0.1 0.025 14.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4974) KH_5 PF13184.6 KII92894.1 - 0.0018 18.3 11.8 0.097 12.8 1.2 5.1 4 0 0 4 4 4 2 NusA-like KH domain RRM_1 PF00076.22 KII92895.1 - 6.3e-11 41.9 0.0 2.6e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KII92895.1 - 2.3e-09 37.1 0.4 5.3e-09 35.9 0.4 1.6 1 0 0 1 1 1 1 Surp module RRM_7 PF16367.5 KII92895.1 - 0.016 15.3 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif CTD_bind PF04818.13 KII92895.1 - 0.062 14.1 0.3 0.2 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Acetyltransf_1 PF00583.25 KII92896.1 - 1.2e-11 44.9 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII92896.1 - 7.9e-08 32.6 0.1 1.5e-07 31.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII92896.1 - 3.7e-06 26.9 0.0 5.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII92896.1 - 0.00051 20.2 0.1 0.00066 19.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII92896.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 KII92896.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 KII92897.1 - 6.3e-09 35.8 9.8 3.1e-05 24.2 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII92897.1 - 1.2e-08 34.9 11.4 9.2e-07 29.0 0.7 3.1 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII92897.1 - 2.8e-07 30.8 7.7 0.01 16.6 3.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII92897.1 - 0.00047 20.4 1.6 0.14 12.5 1.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII92897.1 - 0.0039 17.5 3.2 1.5 9.3 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KII92897.1 - 0.0049 16.8 5.1 0.2 11.7 2.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KII92897.1 - 0.0058 17.3 1.3 0.028 15.1 0.6 1.9 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Ta0938 PF11494.8 KII92897.1 - 0.02 15.2 1.5 0.12 12.7 0.5 1.9 1 1 1 2 2 2 0 Ta0938 YacG PF03884.14 KII92897.1 - 0.057 13.2 0.7 0.11 12.3 0.7 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-MYST PF17772.1 KII92897.1 - 0.13 11.8 1.6 0.73 9.5 0.4 2.1 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 KII92897.1 - 0.44 10.3 5.5 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KII92897.1 - 0.89 10.1 7.1 0.21 12.0 1.9 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 KII92897.1 - 2.5 8.1 5.1 5.4 7.0 0.1 2.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DNA_ligase_A_M PF01068.21 KII92898.1 - 1.3e-40 139.2 0.0 3.3e-37 128.1 0.0 3.0 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KII92898.1 - 1.3e-34 120.0 0.0 8.2e-34 117.4 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KII92898.1 - 1.5e-15 57.6 0.0 4.1e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.6 KII92899.1 - 2.1e-28 99.4 0.0 2.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YrhK PF14145.6 KII92901.1 - 0.11 12.4 19.3 0.24 11.3 1.8 4.5 3 1 0 4 4 4 0 YrhK-like protein DUF973 PF06157.11 KII92901.1 - 0.17 10.9 2.4 0.99 8.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) BolA PF01722.18 KII92903.1 - 1.3e-30 105.5 0.4 1.8e-30 105.1 0.4 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 KII92903.1 - 0.055 13.9 0.1 1.9 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal zf-C2H2 PF00096.26 KII92904.1 - 1.7e-13 50.2 3.3 1.6e-06 28.2 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII92904.1 - 4e-09 36.5 3.3 0.00031 21.3 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII92904.1 - 1.1e-06 28.8 9.6 0.0042 17.4 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KII92904.1 - 0.00039 20.6 0.6 0.00084 19.6 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KII92904.1 - 0.0016 18.3 2.1 0.071 13.0 0.2 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KII92904.1 - 0.0052 16.8 2.8 0.04 13.9 0.7 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KII92904.1 - 0.006 16.9 0.5 0.006 16.9 0.5 2.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KII92904.1 - 0.038 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-Di19 PF05605.12 KII92904.1 - 0.053 13.8 0.8 0.087 13.1 0.8 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 KII92904.1 - 0.092 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 KII92904.1 - 0.16 12.3 0.2 6.1 7.2 0.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 KII92904.1 - 0.18 12.2 0.1 0.26 11.6 0.1 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain zf-BED PF02892.15 KII92904.1 - 0.56 10.3 0.1 0.56 10.3 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 KII92905.1 - 4.8e-60 203.1 0.0 7.1e-39 133.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII92905.1 - 1e-24 87.2 0.2 3.1e-16 59.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KII92905.1 - 6.5e-05 22.4 0.1 0.00067 19.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 KII92905.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII92905.1 - 0.0033 17.4 0.8 0.013 15.4 0.6 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII92905.1 - 0.04 12.7 0.0 0.069 11.9 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Homeodomain PF00046.29 KII92906.1 - 4.4e-16 58.5 3.5 7.6e-16 57.7 3.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII92906.1 - 0.00027 20.7 0.2 0.00078 19.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KII92906.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT ABC_tran PF00005.27 KII92907.1 - 2e-46 157.9 0.0 1e-27 97.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KII92907.1 - 7.7e-14 52.2 0.6 0.0064 16.3 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII92907.1 - 6.4e-12 45.4 0.0 6.9e-05 22.4 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 KII92907.1 - 3.1e-09 36.6 0.1 5.5e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KII92907.1 - 5.3e-07 30.3 0.0 0.0055 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII92907.1 - 1.8e-06 27.6 1.0 0.052 13.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII92907.1 - 5.1e-06 26.6 0.1 0.021 14.9 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KII92907.1 - 4e-05 24.2 0.0 0.2 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII92907.1 - 5.8e-05 23.4 0.0 1.4 9.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KII92907.1 - 7.3e-05 22.7 0.1 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase DUF87 PF01935.17 KII92907.1 - 7.9e-05 22.8 0.6 0.34 11.0 0.0 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_28 PF13521.6 KII92907.1 - 0.00021 21.6 0.0 0.87 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 KII92907.1 - 0.00028 20.9 4.2 2.3 8.7 0.2 4.5 3 0 0 3 3 3 1 HEAT repeat MeaB PF03308.16 KII92907.1 - 0.00048 19.2 0.5 0.2 10.6 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KII92907.1 - 0.00053 20.4 0.1 2.4 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KII92907.1 - 0.00077 19.4 0.2 0.18 11.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 KII92907.1 - 0.0014 18.8 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KII92907.1 - 0.0017 18.1 0.0 2.1 8.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain IFRD PF05004.13 KII92907.1 - 0.0026 16.9 0.3 0.066 12.3 0.1 2.3 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KII92907.1 - 0.0028 18.0 8.0 1 9.8 0.1 3.9 2 1 1 3 3 3 2 HEAT repeats RNA_helicase PF00910.22 KII92907.1 - 0.0093 16.3 0.1 4.8 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KII92907.1 - 0.011 15.9 0.1 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KII92907.1 - 0.016 13.9 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain HEAT_EZ PF13513.6 KII92907.1 - 0.016 15.7 16.3 0.44 11.1 0.5 5.5 4 1 1 5 5 5 0 HEAT-like repeat AAA_30 PF13604.6 KII92907.1 - 0.018 14.8 1.0 7.8 6.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 KII92907.1 - 0.028 14.2 0.2 10 5.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 KII92907.1 - 0.061 13.2 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 KII92907.1 - 0.078 13.0 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KII92907.1 - 0.079 13.0 0.1 0.49 10.4 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.6 KII92907.1 - 0.085 12.6 1.8 2.9 7.5 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 KII92907.1 - 0.096 11.8 0.0 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KII92907.1 - 0.12 12.2 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 KII92907.1 - 0.12 12.0 0.0 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII92907.1 - 0.14 12.0 0.2 35 4.2 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea MMS19_C PF12460.8 KII92907.1 - 0.15 11.1 0.6 0.63 9.1 0.2 2.0 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KII92907.1 - 0.17 10.4 1.1 0.46 9.0 0.9 1.7 1 1 1 2 2 2 0 Adaptin N terminal region cobW PF02492.19 KII92907.1 - 0.19 11.3 0.3 24 4.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.8 KII92907.1 - 0.33 8.4 1.7 4.3 4.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MLANA PF14991.6 KII92908.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A Glyco_hydro_18 PF00704.28 KII92909.1 - 1.4e-84 284.6 1.3 1.5e-84 284.4 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 APG6_N PF17675.1 KII92910.1 - 0.0079 16.7 1.6 0.017 15.6 1.6 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region GIT1_C PF12205.8 KII92910.1 - 0.06 13.5 3.7 0.28 11.3 2.5 2.6 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term RasGAP_C PF03836.15 KII92910.1 - 0.31 11.2 4.4 0.61 10.2 4.4 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Atg14 PF10186.9 KII92910.1 - 0.33 10.0 6.8 0.51 9.4 6.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 KII92910.1 - 2.6 7.8 9.0 5.8 6.7 9.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GTP_EFTU PF00009.27 KII92911.1 - 1.7e-19 70.1 0.0 1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KII92911.1 - 5.5e-07 29.9 0.7 5.5e-07 29.9 0.7 3.3 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KII92911.1 - 6.4e-05 23.2 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KII92911.1 - 0.02 15.0 0.0 0.17 12.0 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase zf-RING_2 PF13639.6 KII92912.1 - 2e-09 37.6 1.2 1.8e-07 31.4 0.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KII92912.1 - 4.6e-08 33.2 0.5 5.6e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KII92912.1 - 2.1e-07 30.7 3.6 6.8e-07 29.0 0.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KII92912.1 - 1.5e-06 27.9 0.5 0.0014 18.3 0.0 3.0 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 KII92912.1 - 1.6e-06 27.8 0.2 1.3e-05 24.9 0.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII92912.1 - 1.7e-05 24.5 0.7 4.6e-05 23.2 0.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KII92912.1 - 0.00012 22.0 5.5 0.0021 18.1 0.8 3.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 KII92912.1 - 0.00021 21.2 1.1 0.00029 20.7 0.1 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KII92912.1 - 0.003 17.6 1.2 0.005 16.9 0.2 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KII92912.1 - 0.018 14.6 0.6 0.049 13.3 0.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KII92912.1 - 0.025 14.4 2.7 0.027 14.3 0.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2631 PF10939.8 KII92912.1 - 0.043 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) zf-C3HC4_4 PF15227.6 KII92912.1 - 0.2 11.9 3.1 0.14 12.3 0.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KII92912.1 - 0.88 9.8 4.2 1.5 9.1 2.3 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain DUF3533 PF12051.8 KII92913.1 - 2.6e-96 322.8 13.6 3e-96 322.6 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ferrochelatase PF00762.19 KII92915.1 - 4.6e-102 341.3 0.0 5.2e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase GHMP_kinases_N PF00288.26 KII92916.1 - 1.1e-12 48.0 1.9 1.1e-12 48.0 1.9 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KII92916.1 - 3.3e-05 24.1 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.18 KII92917.1 - 1.8e-66 224.5 25.6 2e-66 224.4 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KII92919.1 - 1.2e-35 123.0 36.9 1.2e-35 123.0 36.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MS_channel PF00924.18 KII92920.1 - 1.8e-14 53.8 4.2 1.8e-14 53.8 4.2 2.1 2 1 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KII92920.1 - 0.041 13.4 0.2 0.12 12.0 0.2 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KII92920.1 - 0.2 11.7 0.4 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 KII92921.1 - 7.9e-63 212.3 0.0 1.7e-62 211.3 0.0 1.5 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain ALP_N PF17989.1 KII92921.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Actin like proteins N terminal domain GATase_7 PF13537.6 KII92922.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain V_ATPase_I PF01496.19 KII92924.1 - 2 6.2 5.7 2.8 5.7 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HhH-GPD PF00730.25 KII92925.1 - 1.1e-09 38.7 0.0 1.3e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SseB PF07179.12 KII92925.1 - 0.14 12.4 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 SseB protein N-terminal domain PRR20 PF15708.5 KII92926.1 - 0.0015 18.5 0.3 0.0028 17.6 0.3 1.4 1 0 0 1 1 1 1 Proline-rich protein family 20 FXMRP1_C_core PF12235.8 KII92926.1 - 0.045 14.4 1.4 0.045 14.4 1.4 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF1115 PF06544.12 KII92927.1 - 0.0075 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.18 KII92927.1 - 0.067 13.6 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 Acylphosphatase AAA_lid_9 PF17871.1 KII92929.1 - 4.2e-17 62.0 0.5 9.1e-16 57.7 0.5 2.1 1 1 0 1 1 1 1 AAA lid domain Tet_JBP PF12851.7 KII92930.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily TMEM100 PF16311.5 KII92931.1 - 1.4 8.5 5.6 1.6 8.3 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 Herpes_capsid PF06112.11 KII92933.1 - 0.012 15.6 3.3 0.02 15.0 3.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ArgJ PF01960.18 KII92934.1 - 3.5e-16 58.9 0.0 4.2e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 ArgJ family RAP-1 PF03085.15 KII92937.1 - 0.097 12.4 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Zn_clus PF00172.18 KII92939.1 - 5.4e-09 36.0 12.3 1e-08 35.1 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMtag PF10159.9 KII92943.1 - 3.1e-30 104.3 1.2 3.1e-30 104.3 1.2 3.0 3 0 0 3 3 3 1 Multiple myeloma tumor-associated PWWP PF00855.17 KII92944.1 - 3.4e-19 69.0 0.0 3.4e-19 69.0 0.0 2.5 1 1 1 2 2 2 1 PWWP domain Med26 PF08711.11 KII92944.1 - 0.023 14.7 0.1 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF3083 PF11281.8 KII92944.1 - 0.042 13.2 0.1 0.61 9.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3083) Ndc1_Nup PF09531.10 KII92944.1 - 7.4 5.1 5.1 8.7 4.9 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 KII92944.1 - 7.7 5.2 8.5 10 4.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 KII92944.1 - 9 4.3 10.0 13 3.8 10.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BCS1_N PF08740.11 KII92945.1 - 6e-39 134.0 5.9 6e-39 134.0 5.9 3.1 2 2 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KII92945.1 - 6.9e-15 55.6 0.0 3.5e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KII92945.1 - 0.00026 20.7 0.1 0.027 14.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 KII92945.1 - 0.0063 15.7 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KII92945.1 - 0.0082 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KII92945.1 - 0.0089 16.4 0.1 0.0089 16.4 0.1 2.6 2 2 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.27 KII92945.1 - 0.1 13.1 4.6 0.19 12.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KII92945.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain DUF4887 PF16228.5 KII92945.1 - 0.28 11.3 37.9 0.029 14.5 27.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) Macoilin PF09726.9 KII92945.1 - 0.74 8.3 13.2 1.3 7.5 13.2 1.3 1 0 0 1 1 1 0 Macoilin family FtsK_SpoIIIE PF01580.18 KII92945.1 - 0.82 9.0 3.2 41 3.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 KII92945.1 - 0.89 10.0 18.4 12 6.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 KII92945.1 - 1 9.1 11.6 43 3.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KII92945.1 - 2.3 8.1 4.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase RIC3 PF15361.6 KII92945.1 - 4.8 7.6 8.4 16 5.9 8.4 1.9 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MBOAT_2 PF13813.6 KII92946.1 - 3.1e-17 62.6 2.2 3.1e-17 62.6 2.2 3.4 3 1 0 3 3 3 1 Membrane bound O-acyl transferase family TFIIS_C PF01096.18 KII92948.1 - 0.021 14.7 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Imm27 PF15590.6 KII92948.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 27 Sec2p PF06428.11 KII92949.1 - 1.7e-10 40.7 13.4 1.7e-10 40.7 13.4 3.0 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 KII92949.1 - 0.51 8.2 5.7 3.6 5.4 0.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KII92949.1 - 4.7 6.0 21.8 4.9 5.9 12.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GCN5L1 PF06320.13 KII92949.1 - 6.1 7.0 14.7 0.46 10.7 8.4 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) SET PF00856.28 KII92950.1 - 1.6e-09 38.4 0.1 1.6e-09 38.4 0.1 3.0 2 2 0 2 2 2 1 SET domain Ribosomal_S8e PF01201.22 KII92951.1 - 3.7e-57 192.3 1.1 5.2e-57 191.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e GlutR_dimer PF00745.20 KII92951.1 - 0.066 13.7 0.6 0.22 12.0 0.1 1.9 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain UDPGP PF01704.18 KII92952.1 - 9.5e-198 656.9 1.9 1.1e-197 656.7 1.9 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.18 KII92953.1 - 1.2e-199 663.2 1.4 1.3e-199 663.0 1.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.28 KII92954.1 - 8.7e-15 55.8 0.4 1.3e-14 55.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NADH_B2 PF14813.6 KII92955.1 - 0.011 15.6 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Cytochrome_CBB3 PF13442.6 KII92957.1 - 0.042 14.2 0.2 0.072 13.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III MtrF PF09472.10 KII92957.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ABM PF03992.16 KII92958.1 - 1.8e-06 28.0 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PAP1 PF08601.10 KII92960.1 - 0.34 10.6 8.1 0.4 10.4 8.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Sporozoite_P67 PF05642.11 KII92960.1 - 7.7 4.5 21.6 9.2 4.2 21.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Polyoma_coat2 PF00761.20 KII92960.1 - 8.5 6.0 12.9 12 5.5 12.9 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein ELP6 PF09807.9 KII92961.1 - 3.8e-17 62.5 0.0 2.9e-16 59.7 0.0 1.9 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KII92961.1 - 2.4e-05 24.0 0.2 3.3e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 AAA_25 PF13481.6 KII92961.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec34 PF04136.15 KII92962.1 - 3.7e-47 159.9 0.0 7.6e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family S6PP_C PF08472.10 KII92962.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal DIOX_N PF14226.6 KII92963.1 - 1.3e-28 100.1 0.0 2.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII92963.1 - 3.4e-19 69.2 0.0 6.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dimer_Tnp_hAT PF05699.14 KII92967.1 - 0.00042 20.0 0.2 0.00076 19.2 0.2 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.16 KII92968.1 - 3.1e-15 55.9 28.9 4.5e-15 55.4 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KII92968.1 - 2.5e-07 30.6 2.9 2.5e-07 30.6 2.9 2.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Cpn60_TCP1 PF00118.24 KII92969.1 - 1.2e-161 538.7 0.3 1.5e-161 538.4 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short_C2 PF13561.6 KII92970.1 - 3.3e-55 187.2 0.8 4.1e-55 186.9 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII92970.1 - 2.3e-43 147.9 0.4 3.3e-43 147.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII92970.1 - 4.8e-11 42.9 0.4 2.1e-10 40.8 0.4 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KII92970.1 - 0.013 16.2 0.0 0.033 14.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Big_7 PF17957.1 KII92970.1 - 0.51 11.1 3.7 0.59 10.9 0.5 2.5 3 0 0 3 3 3 0 Bacterial Ig domain Metallophos PF00149.28 KII92971.1 - 3.7e-09 37.4 0.0 6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3302 PF11742.8 KII92971.1 - 0.3 11.2 2.7 0.86 9.8 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) BSD PF03909.17 KII92972.1 - 2.8e-11 43.2 0.0 9.1e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 BSD domain KfrA_N PF11740.8 KII92972.1 - 0.00022 21.9 4.9 0.0065 17.1 0.2 3.0 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term DinB_2 PF12867.7 KII92972.1 - 0.0038 17.7 0.3 0.89 10.1 0.0 2.9 2 0 0 2 2 2 1 DinB superfamily DUF4456 PF14644.6 KII92972.1 - 0.019 14.7 2.0 0.86 9.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) DUF2277 PF10041.9 KII92972.1 - 0.053 13.9 2.1 2.7 8.4 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) DUF883 PF05957.13 KII92972.1 - 0.1 13.2 4.9 2.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) GTP-bdg_M PF16360.5 KII92972.1 - 0.13 12.9 2.0 3.7 8.2 0.0 3.0 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Phasin_2 PF09361.10 KII92972.1 - 0.15 12.3 3.1 2.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Phasin protein OmpH PF03938.14 KII92972.1 - 0.29 11.5 2.3 8.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HIP1_clath_bdg PF16515.5 KII92972.1 - 0.81 10.3 4.4 21 5.8 0.9 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CPSase_sm_chain PF00988.22 KII92973.1 - 1.4e-45 154.3 0.0 2e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KII92973.1 - 5e-38 130.8 0.0 6.6e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KII92973.1 - 3.3e-08 33.5 0.1 2.8e-06 27.3 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KII92973.1 - 0.029 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Scs3p PF10261.9 KII92974.1 - 5.2e-41 140.8 6.2 3e-34 118.6 0.3 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM SPT_ssu-like PF11779.8 KII92974.1 - 0.022 14.4 2.0 0.066 12.9 0.2 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like PAP2 PF01569.21 KII92974.1 - 0.029 14.1 0.8 0.029 14.1 0.8 2.7 3 0 0 3 3 3 0 PAP2 superfamily Glyco_hydro_38N PF01074.22 KII92975.1 - 1.5e-76 257.5 0.1 2.4e-76 256.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KII92975.1 - 3.3e-51 174.4 0.0 5e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KII92975.1 - 5e-27 93.9 0.0 9.9e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KII92975.1 - 7.1e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Aldedh PF00171.22 KII92976.1 - 2.9e-78 263.4 0.0 3.5e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 KII92976.1 - 0.15 13.0 0.0 0.44 11.5 0.0 1.8 1 0 0 1 1 1 0 Fic/DOC family ALAD PF00490.21 KII92977.1 - 3e-122 407.7 0.0 3.7e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Aldedh PF00171.22 KII92978.1 - 1.9e-78 264.1 0.0 2.3e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 KII92978.1 - 0.05 14.5 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 Fic/DOC family Aldedh PF00171.22 KII92979.1 - 3.6e-84 282.9 0.0 4.5e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PRCC PF10253.9 KII92979.1 - 0.061 14.1 0.1 0.096 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Shisa PF13908.6 KII92981.1 - 0.00054 20.3 0.0 0.00073 19.8 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 KII92981.1 - 0.0018 18.9 8.4 0.0035 18.0 8.4 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KII92981.1 - 0.0082 17.0 0.0 0.015 16.2 0.0 1.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 KII92981.1 - 0.0086 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 KII92981.1 - 0.032 14.0 4.7 0.052 13.3 4.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 m04gp34like PF12216.8 KII92981.1 - 0.04 13.5 0.0 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Immune evasion protein TMIE PF16038.5 KII92981.1 - 0.062 13.1 1.4 0.097 12.5 1.4 1.2 1 0 0 1 1 1 0 TMIE protein SepSecS PF05889.13 KII92981.1 - 0.17 10.5 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF2207 PF09972.9 KII92981.1 - 0.27 10.0 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cyt-b5 PF00173.28 KII92983.1 - 2.4e-06 27.6 0.3 0.014 15.5 0.2 2.2 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain G-alpha PF00503.20 KII92984.1 - 2.4e-120 401.9 0.0 2.8e-120 401.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII92984.1 - 1.8e-16 60.1 1.2 1.1e-11 44.5 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII92984.1 - 4.1e-05 23.1 1.1 0.0023 17.3 0.0 2.6 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KII92984.1 - 0.0035 17.5 0.5 2.6 8.3 0.0 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 KII92984.1 - 0.026 14.3 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger GTP_EFTU PF00009.27 KII92984.1 - 0.046 13.3 0.0 11 5.5 0.0 3.1 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KII92984.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KII92984.1 - 0.06 13.4 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KII92984.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GNVR PF13807.6 KII92987.1 - 0.49 10.3 2.9 0.79 9.7 0.3 2.7 1 1 2 3 3 3 0 G-rich domain on putative tyrosine kinase EURL PF06937.11 KII92989.1 - 0.095 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 EURL protein KDZ PF18758.1 KII92992.1 - 0.0014 18.2 0.2 0.002 17.8 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase AA_permease_N PF08403.10 KII92992.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal CcmD PF04995.14 KII92992.1 - 3.7 7.7 5.5 0.42 10.7 0.6 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DLH PF01738.18 KII92995.1 - 2e-24 86.3 0.0 2.3e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KII92995.1 - 0.0084 15.8 0.2 1.6 8.3 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII92995.1 - 0.15 12.6 3.5 0.34 11.5 3.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4598 PF15370.6 KII92996.1 - 1.4e-22 80.2 1.4 1.4e-22 80.2 1.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) AF-4 PF05110.13 KII92996.1 - 0.077 11.1 9.4 0.071 11.2 9.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DNA_pol_phi PF04931.13 KII92996.1 - 0.29 9.2 5.1 0.32 9.1 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Dus PF01207.17 KII92997.1 - 1.1e-83 281.0 0.0 5.1e-74 249.2 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 KII92997.1 - 0.00038 20.3 0.1 0.028 14.2 0.1 2.3 1 1 1 2 2 2 2 SOR/SNZ family NMO PF03060.15 KII92997.1 - 0.00093 18.7 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KII92997.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PGF-CTERM PF18204.1 KII92997.1 - 0.071 13.1 3.4 7.2 6.7 0.3 2.6 2 0 0 2 2 2 0 PGF-CTERM motif Paramyx_P_V_C PF03210.13 KII92997.1 - 0.14 12.0 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal ApbA_C PF08546.11 KII92998.1 - 1e-20 74.2 0.0 7.5e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KII92998.1 - 2.8e-18 66.0 0.0 4.8e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KII92998.1 - 0.048 13.0 0.1 0.095 12.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family ApbA_C PF08546.11 KII92999.1 - 1.4e-19 70.5 0.0 6.2e-17 62.0 0.0 2.7 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KII92999.1 - 8.1e-17 61.3 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 KII92999.1 - 0.03 13.9 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KII92999.1 - 0.15 12.5 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ubiquitin PF00240.23 KII93000.1 - 1.4e-19 69.6 0.3 2.2e-19 69.0 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KII93000.1 - 3.4e-11 42.8 0.1 8.9e-11 41.5 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 KII93000.1 - 2.1e-09 37.1 0.5 3.6e-09 36.3 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KII93000.1 - 4.5e-07 30.4 0.1 7.6e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 KII93000.1 - 0.0093 15.9 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KII93000.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KII93000.1 - 0.031 14.3 0.8 0.87 9.7 0.3 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain GerD PF17898.1 KII93000.1 - 0.035 14.1 2.8 0.083 12.9 2.8 1.6 1 1 0 1 1 1 0 Spore germination GerD central core domain Ubiquitin_5 PF18037.1 KII93000.1 - 0.036 14.4 0.2 0.066 13.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 KII93000.1 - 0.078 12.7 2.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 CUE domain Phage_tail_X PF05489.12 KII93000.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Phage Tail Protein X HOIP-UBA PF16678.5 KII93000.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 KII93000.1 - 0.31 11.0 11.7 1.7 8.7 7.0 3.2 1 1 1 2 2 2 0 STI1 domain XPC-binding PF09280.11 KII93000.1 - 0.32 10.8 17.7 0.075 12.8 5.3 4.1 3 1 2 5 5 5 0 XPC-binding domain C2 PF00168.30 KII93001.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 C2 domain EI24 PF07264.11 KII93002.1 - 2.7e-05 24.5 6.3 4.2e-05 23.9 6.1 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Bac_export_2 PF01312.19 KII93003.1 - 0.45 9.7 7.6 0.65 9.1 7.6 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Pkinase_fungal PF17667.1 KII93004.1 - 4.4e-73 246.4 3.8 1.9e-38 132.3 0.0 2.5 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KII93004.1 - 8.8e-06 25.3 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93004.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AhpC-TSA_2 PF13911.6 KII93005.1 - 9.7e-24 83.7 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KII93005.1 - 3.5e-08 33.4 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII93005.1 - 7.9e-07 28.9 0.0 1.8e-06 27.7 0.0 1.5 1 1 1 2 2 2 1 Redoxin Pkinase PF00069.25 KII93007.1 - 2.1e-73 247.0 0.0 2.8e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93007.1 - 5.2e-39 134.1 0.0 7.4e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KII93007.1 - 7.9e-17 61.8 0.5 8.3e-14 52.0 0.5 3.2 1 1 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KII93007.1 - 3.4e-13 49.5 0.3 8.8e-13 48.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KII93007.1 - 2.3e-06 27.1 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KII93007.1 - 0.0017 18.0 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KII93007.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII93007.1 - 0.051 13.5 1.8 0.2 11.5 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KII93007.1 - 0.14 11.5 0.2 0.74 9.1 0.2 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Heme_oxygenase PF01126.20 KII93008.1 - 0.021 14.6 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Heme oxygenase Peptidase_S46 PF10459.9 KII93008.1 - 2.5 6.7 6.5 0.24 10.0 1.9 1.5 2 0 0 2 2 2 0 Peptidase S46 HNH_2 PF13391.6 KII93009.1 - 2.9e-07 30.5 0.0 6.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 KII93012.1 - 4.7e-08 33.1 0.0 8.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease SRP14 PF02290.15 KII93013.1 - 3.2e-24 85.1 1.8 1.6e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF3110 PF11360.8 KII93013.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) GP4 PF03010.14 KII93013.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 GP4 DUF3959 PF13105.6 KII93013.1 - 0.25 10.8 1.5 0.29 10.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) zf-C3HC4_3 PF13920.6 KII93014.1 - 0.0001 22.1 11.1 0.00018 21.3 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 KII93014.1 - 0.00054 20.1 0.5 0.00071 19.7 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus NUDE_C PF04880.13 KII93014.1 - 0.02 15.4 3.5 0.027 14.9 3.5 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region zf-RING_5 PF14634.6 KII93014.1 - 0.044 13.7 12.4 0.072 13.1 12.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain OmpH PF03938.14 KII93014.1 - 0.05 13.9 5.6 0.067 13.5 5.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-RING_2 PF13639.6 KII93014.1 - 0.092 13.1 13.1 0.14 12.5 13.1 1.3 1 0 0 1 1 1 0 Ring finger domain DUF3450 PF11932.8 KII93014.1 - 0.2 10.9 7.8 0.27 10.5 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RmuC PF02646.16 KII93014.1 - 0.23 10.5 4.8 0.54 9.3 5.1 1.4 1 1 1 2 2 2 0 RmuC family DUF16 PF01519.16 KII93014.1 - 0.35 11.4 4.5 0.48 10.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prok-RING_4 PF14447.6 KII93014.1 - 0.47 10.3 10.8 0.92 9.4 10.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_13 PF13166.6 KII93014.1 - 1.7 7.2 5.3 2.2 6.8 5.3 1.1 1 0 0 1 1 1 0 AAA domain zf-C3HC4_2 PF13923.6 KII93014.1 - 2.8 7.9 12.8 4.6 7.2 12.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nramp PF01566.18 KII93016.1 - 1.6e-86 290.5 29.0 3.3e-49 167.8 5.6 2.4 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein PsaL PF02605.15 KII93016.1 - 0.2 11.3 5.3 0.11 12.2 0.8 2.6 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI EthD PF07110.11 KII93017.1 - 1.1e-12 49.0 0.0 1.3e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KII93017.1 - 7.7e-07 29.6 0.0 9.2e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF4543 PF15076.6 KII93017.1 - 0.026 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Histone PF00125.24 KII93018.1 - 1e-49 168.2 3.9 1.1e-49 168.1 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KII93018.1 - 2.5e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KII93018.1 - 9.6e-05 22.5 1.2 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KII93018.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 KII93018.1 - 0.002 18.8 2.1 0.0025 18.4 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Bromo_TP PF07524.13 KII93018.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KII93018.1 - 0.095 12.8 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit EthD PF07110.11 KII93019.1 - 3.6e-14 53.7 0.0 4.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KII93019.1 - 0.00014 22.3 0.0 0.00021 21.7 0.0 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase EthD PF07110.11 KII93020.1 - 1.6e-17 64.5 0.0 2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KII93020.1 - 3.7e-07 30.6 0.0 4.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase IucA_IucC PF04183.12 KII93020.1 - 0.065 12.8 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family MOZART2 PF12926.7 KII93020.1 - 0.097 12.3 1.2 5.7 6.6 0.1 2.9 1 1 1 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF726 PF05277.12 KII93021.1 - 2e-123 411.7 1.5 3.1e-123 411.1 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.20 KII93021.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3541 PF12060.8 KII93021.1 - 0.057 13.1 0.8 0.097 12.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) DUF1115 PF06544.12 KII93023.1 - 1.3e-05 25.3 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RRM_1 PF00076.22 KII93024.1 - 1e-18 66.9 0.0 1.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII93024.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KII93024.1 - 0.012 15.5 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.11 KII93024.1 - 0.064 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain F-box-like PF12937.7 KII93025.1 - 0.0054 16.6 4.1 0.012 15.4 4.1 1.7 1 0 0 1 1 1 1 F-box-like Peptidase_M17 PF00883.21 KII93026.1 - 5.5e-117 390.5 0.0 6.7e-117 390.2 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KII93026.1 - 2.1e-05 24.3 0.2 4.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain F-box-like PF12937.7 KII93029.1 - 0.013 15.4 0.4 0.046 13.6 0.4 2.0 1 1 0 1 1 1 0 F-box-like HNH_2 PF13391.6 KII93031.1 - 1.3e-08 34.9 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 KII93032.1 - 5.3e-05 23.0 2.8 0.0045 16.8 1.6 3.2 2 1 0 2 2 2 2 F-box-like Chordopox_RPO7 PF05864.12 KII93032.1 - 0.17 12.1 0.2 0.37 11.1 0.2 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) F-box-like PF12937.7 KII93033.1 - 0.0026 17.6 0.4 0.0041 17.0 0.1 1.5 2 0 0 2 2 2 1 F-box-like DUF3404 PF11884.8 KII93033.1 - 0.086 12.0 0.2 0.1 11.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) LRR_8 PF13855.6 KII93034.1 - 0.29 10.9 5.1 0.76 9.6 0.3 3.5 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KII93034.1 - 0.33 11.4 6.7 1.1 9.8 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII93035.1 - 6e-06 26.0 0.3 2.2e-05 24.2 0.3 2.1 1 1 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.20 KII93036.1 - 2.3e-19 69.9 0.1 3.3e-16 59.6 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KII93036.1 - 7.4e-09 35.6 4.4 0.00011 21.8 0.1 2.9 3 0 0 3 3 3 2 Amidohydrolase family F-box-like PF12937.7 KII93037.1 - 0.01 15.7 0.5 0.023 14.6 0.5 1.6 1 0 0 1 1 1 0 F-box-like PUF PF00806.19 KII93039.1 - 3e-28 95.9 0.2 2.1e-07 30.3 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat F-box-like PF12937.7 KII93040.1 - 6e-07 29.3 1.4 8.2e-05 22.4 0.3 3.1 2 1 0 2 2 2 2 F-box-like Pkinase PF00069.25 KII93042.1 - 1e-08 34.9 0.0 3.1e-08 33.3 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93042.1 - 0.0002 20.7 0.0 0.00048 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93044.1 - 5.2e-07 29.3 0.0 4.8e-06 26.1 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93044.1 - 0.028 13.7 0.0 0.13 11.5 0.0 2.2 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KII93045.1 - 2.3e-10 40.3 0.0 6.7e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93045.1 - 0.00024 20.5 0.0 0.0015 17.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KII93045.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KII93046.1 - 7e-08 32.2 0.0 2.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93046.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KII93048.1 - 2.8e-10 40.0 0.0 3.5e-09 36.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93048.1 - 0.00023 20.5 0.0 0.0012 18.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KII93048.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Flu_PA PF00603.17 KII93053.1 - 0.15 10.1 0.0 0.16 10.1 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA Pkinase PF00069.25 KII93054.1 - 7.8e-11 41.8 0.0 1.5e-08 34.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93054.1 - 0.00024 20.5 0.0 0.0013 18.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93056.1 - 4.2e-09 36.1 0.0 8.1e-08 31.9 0.0 2.8 1 1 1 2 2 2 1 Protein kinase domain Glutaredoxin PF00462.24 KII93057.1 - 2.9e-18 65.8 0.1 3.8e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 KII93057.1 - 5.8e-05 23.1 0.0 7.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 KII93057.1 - 0.001 19.4 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 KII93057.1 - 0.003 18.0 0.1 0.0087 16.5 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 KII93057.1 - 0.028 14.6 0.2 4.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin DSBA PF01323.20 KII93057.1 - 0.064 13.0 0.6 0.89 9.3 0.2 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Pkinase PF00069.25 KII93058.1 - 0.0014 18.1 0.0 0.034 13.5 0.0 3.0 4 0 0 4 4 4 1 Protein kinase domain DUF4632 PF15451.6 KII93059.1 - 1.2 9.2 4.5 0.62 10.2 1.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4632) Pkinase PF00069.25 KII93060.1 - 8.9e-10 38.4 0.0 2.7e-07 30.2 0.0 2.7 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93060.1 - 0.0082 15.5 0.0 0.089 12.1 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93061.1 - 2.5e-07 30.4 0.0 5.5e-05 22.7 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.25 KII93063.1 - 2.2e-10 40.4 0.0 1.5e-08 34.4 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93063.1 - 0.069 12.4 0.0 0.25 10.6 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KII93064.1 - 2.2e-07 30.5 0.0 5.6e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 KII93066.1 - 1.2e-11 44.5 0.0 1.2e-10 41.3 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93066.1 - 5.4e-05 22.6 0.0 0.00031 20.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93067.1 - 3.8e-07 29.7 0.0 2.5e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93067.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93068.1 - 0.011 15.2 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain AAA_33 PF13671.6 KII93068.1 - 0.068 13.3 0.1 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NIF3 PF01784.18 KII93069.1 - 3.5e-63 213.5 0.0 4.4e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Phage_Mu_Gp45 PF06890.12 KII93069.1 - 0.0049 16.6 0.8 1.9 8.3 0.2 2.4 2 0 0 2 2 2 2 Bacteriophage Mu Gp45 protein PfkB PF00294.24 KII93069.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ala_racemase_C PF00842.21 KII93069.1 - 0.061 13.1 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain FAD_binding_3 PF01494.19 KII93071.1 - 2.5e-33 115.8 0.4 4.1e-33 115.1 0.2 1.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KII93072.1 - 2.7e-10 40.0 0.1 2.9e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KII93072.1 - 1.6e-06 28.2 0.0 2e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII93072.1 - 0.00013 21.3 0.1 0.00013 21.3 0.1 1.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KII93072.1 - 0.00013 21.2 0.2 0.00013 21.2 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KII93072.1 - 0.00017 20.9 0.2 0.00017 20.9 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII93072.1 - 0.00029 20.2 0.2 0.00032 20.1 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII93072.1 - 0.00034 19.4 0.2 0.00034 19.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KII93072.1 - 0.00045 19.9 0.1 0.00045 19.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KII93072.1 - 0.0012 18.0 0.4 0.0012 18.0 0.4 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KII93072.1 - 0.014 14.8 0.1 0.016 14.6 0.1 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII93072.1 - 0.058 13.4 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KII93072.1 - 0.079 12.2 0.0 0.091 12.0 0.0 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KII93072.1 - 0.091 13.3 0.1 0.091 13.3 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Adaptin_N PF01602.20 KII93074.1 - 1.1e-92 311.3 5.0 1.7e-92 310.7 5.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KII93074.1 - 5.2e-60 201.0 0.0 1.2e-59 199.8 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KII93074.1 - 1.7e-53 180.3 0.0 4.5e-53 178.9 0.0 1.8 2 0 0 2 2 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KII93074.1 - 3.1e-09 37.1 0.1 0.013 15.8 0.0 4.9 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 KII93074.1 - 4.3e-08 32.7 0.2 0.27 11.6 0.0 5.7 4 1 1 5 5 5 1 HEAT repeat DUF5578 PF17741.1 KII93074.1 - 8.8e-07 28.6 2.9 0.003 17.0 0.6 2.9 2 1 1 3 3 3 2 Family of unknown function (DUF5578) Cnd1 PF12717.7 KII93074.1 - 7.5e-06 26.1 6.3 0.0019 18.3 0.0 3.9 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 KII93074.1 - 0.00056 20.0 0.0 0.0066 16.6 0.0 2.8 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform RTP1_C1 PF10363.9 KII93074.1 - 0.00074 19.7 1.9 0.19 11.9 0.0 3.7 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 KII93074.1 - 0.0042 17.5 1.3 2.7 8.4 0.0 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF5071 PF16804.5 KII93074.1 - 0.0063 16.8 0.2 0.16 12.2 0.0 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF5071) Meis_PKNOX_N PF16493.5 KII93074.1 - 0.0095 16.3 0.6 0.038 14.3 0.6 2.0 1 0 0 1 1 1 1 N-terminal of Homeobox Meis and PKNOX1 ParcG PF10274.9 KII93074.1 - 0.01 16.0 0.5 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 Parkin co-regulated protein Gemini_V2 PF01524.17 KII93074.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 Geminivirus V2 protein Transp_cyt_pur PF02133.15 KII93075.1 - 8.4e-32 110.5 27.9 1.2e-31 109.9 27.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fasciclin PF02469.22 KII93078.1 - 1.5e-07 31.7 0.0 2.3e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain DPM3 PF08285.11 KII93079.1 - 1.3e-31 108.6 0.3 1.4e-31 108.5 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4381 PF14316.6 KII93079.1 - 0.13 12.5 0.5 0.2 11.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ERG2_Sigma1R PF04622.12 KII93080.1 - 2.7e-93 311.1 0.0 3.2e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein CSTF2_hinge PF14327.6 KII93081.1 - 1.8e-10 41.1 6.3 1.9e-10 41.0 0.5 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 KII93081.1 - 8.3e-07 28.5 0.9 8.3e-07 28.5 0.9 1.8 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal Peptidase_M43 PF05572.13 KII93082.1 - 3.3e-18 66.1 0.7 6.1e-18 65.2 0.1 1.7 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KII93082.1 - 5.8e-06 26.6 1.7 8.4e-06 26.1 1.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KII93082.1 - 0.00027 21.5 0.3 0.00049 20.6 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KII93082.1 - 0.00033 20.4 0.5 0.0011 18.6 0.3 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KII93082.1 - 0.015 15.1 0.1 0.026 14.4 0.1 1.3 1 1 0 1 1 1 0 Matrixin Peptidase_M7 PF02031.16 KII93082.1 - 0.039 14.1 1.3 0.054 13.6 0.1 1.8 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KII93082.1 - 0.073 12.0 0.4 0.13 11.2 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 KII93083.1 - 7.7e-15 55.1 0.5 1.6e-14 54.1 0.5 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KII93083.1 - 1.3e-05 25.4 0.1 2e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 KII93083.1 - 0.0043 17.2 0.9 0.0093 16.1 0.9 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 KII93083.1 - 0.0088 15.0 0.2 0.012 14.5 0.2 1.4 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 KII93083.1 - 0.011 16.3 0.0 0.016 15.7 0.0 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KII93083.1 - 0.032 14.1 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KII93083.1 - 0.044 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like F-box-like PF12937.7 KII93084.1 - 1e-09 38.1 0.4 3e-09 36.6 0.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KII93084.1 - 0.078 12.9 3.7 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 F-box domain TetR_C_33 PF13305.6 KII93084.1 - 0.13 13.0 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sin3_corepress PF08295.12 KII93084.1 - 0.19 11.8 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Sin3 family co-repressor ubiquitin PF00240.23 KII93085.1 - 2.7e-34 116.8 0.4 3e-34 116.6 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KII93085.1 - 5.1e-15 55.1 0.3 5.7e-15 54.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KII93085.1 - 6.9e-06 26.4 0.1 3.1e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KII93085.1 - 0.0019 18.1 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KII93085.1 - 0.002 18.5 0.1 0.0022 18.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KII93085.1 - 0.0031 17.6 0.1 0.0072 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KII93085.1 - 0.018 15.1 0.2 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KII93085.1 - 0.02 15.5 0.1 0.023 15.2 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain NSs PF11073.8 KII93086.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Adap_comp_sub PF00928.21 KII93087.1 - 3.2e-23 82.5 0.0 5.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KII93087.1 - 1.4e-07 31.6 0.1 2.1e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.6 KII93087.1 - 4.5 7.4 4.9 7.5 6.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Aldo_ket_red PF00248.21 KII93088.1 - 2.3e-67 227.3 0.0 2.7e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII93089.1 - 4.6e-62 209.9 0.0 5.5e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RETICULATA-like PF11891.8 KII93089.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein RETICULATA-related TPX2 PF06886.11 KII93091.1 - 1.5e-11 44.3 22.9 1.5e-11 44.3 22.9 1.5 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) TraT PF05818.12 KII93091.1 - 0.052 13.2 0.0 0.061 13.0 0.0 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Oxysterol_BP PF01237.18 KII93091.1 - 0.34 9.7 4.0 0.34 9.7 4.0 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein DUF5595 PF18077.1 KII93091.1 - 0.91 9.7 6.1 1.4 9.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) ECH_1 PF00378.20 KII93093.1 - 3.1e-49 167.6 0.0 4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KII93093.1 - 1.1e-26 94.2 0.0 1.3e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M76 PF09768.9 KII93094.1 - 3e-69 232.2 4.5 3.7e-69 231.9 4.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KII93094.1 - 0.051 13.4 3.2 0.1 12.5 2.8 1.6 1 1 0 1 1 1 0 SprT-like family GPI-anchored PF10342.9 KII93096.1 - 5e-09 36.8 0.2 5e-09 36.8 0.2 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ATG27 PF09451.10 KII93099.1 - 8.5e-12 45.5 0.0 1e-10 41.9 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KII93099.1 - 2.7e-11 43.7 0.2 0.00012 22.2 0.1 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 KII93099.1 - 1.8e-08 33.8 0.0 2.4e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF2207 PF09972.9 KII93099.1 - 0.074 11.8 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Complex1_49kDa PF00346.19 KII93100.1 - 3.8e-119 396.8 0.0 4.8e-119 396.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KII93100.1 - 0.0043 16.0 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Fungal_trans PF04082.18 KII93101.1 - 1.7e-19 69.9 1.6 3.9e-19 68.7 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII93101.1 - 4.6e-05 23.5 13.7 9.7e-05 22.4 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DASH_Spc19 PF08287.11 KII93101.1 - 0.087 12.7 0.6 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 Spc19 Utp14 PF04615.13 KII93102.1 - 2.5e-202 674.5 56.0 2.5e-202 674.5 56.0 2.1 1 1 1 2 2 2 1 Utp14 protein Tetraspanin PF00335.20 KII93103.1 - 3e-09 36.9 12.1 4.1e-09 36.5 12.1 1.1 1 0 0 1 1 1 1 Tetraspanin family FTR1 PF03239.14 KII93103.1 - 0.021 14.0 0.5 0.037 13.2 0.5 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family EMC3_TMCO1 PF01956.16 KII93103.1 - 1.7 8.3 6.4 6.4 6.5 0.2 2.4 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF202 PF02656.15 KII93103.1 - 10 6.7 8.0 3.5 8.1 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DIOX_N PF14226.6 KII93104.1 - 4.4e-16 59.7 0.0 7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII93104.1 - 1.5e-13 51.1 0.0 2.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KII93105.1 - 1.1e-14 55.2 0.0 1.7e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII93105.1 - 1.7e-12 47.7 0.0 3.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rhodanese PF00581.20 KII93106.1 - 7.6e-06 26.4 0.0 9.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HicA_toxin PF07927.12 KII93107.1 - 3.7e-06 26.9 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, EF-hand_6 PF13405.6 KII93107.1 - 0.041 13.8 0.5 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Minor_capsid_1 PF10665.9 KII93108.1 - 0.091 13.0 0.6 0.17 12.1 0.3 1.6 1 1 0 1 1 1 0 Minor capsid protein TPR_MLP1_2 PF07926.12 KII93108.1 - 0.096 12.7 10.5 0.18 11.8 4.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KII93108.1 - 0.13 11.1 9.6 0.15 11.0 9.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 KII93108.1 - 0.22 11.9 9.5 0.13 12.6 7.7 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) NBD94 PF16830.5 KII93108.1 - 0.27 11.6 4.9 0.29 11.6 2.2 2.0 1 1 1 2 2 2 0 Nucleotide-Binding Domain 94 of RH CCDC-167 PF15188.6 KII93108.1 - 0.27 11.6 0.3 0.27 11.6 0.3 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.12 KII93108.1 - 0.36 10.9 3.7 5.5 7.0 2.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CREPT PF16566.5 KII93108.1 - 0.63 10.2 8.8 0.17 12.1 4.4 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Fib_alpha PF08702.10 KII93108.1 - 0.86 9.8 8.2 3.3 7.9 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KII93108.1 - 1.4 8.2 10.9 1.8 7.8 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KII93108.1 - 3 8.5 7.5 3.6 8.3 0.8 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Swi5 PF07061.11 KII93108.1 - 4.1 7.6 8.7 0.49 10.5 1.0 2.4 2 1 0 2 2 2 0 Swi5 TMPIT PF07851.13 KII93108.1 - 4.2 6.5 10.3 1.1 8.4 2.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein XhlA PF10779.9 KII93108.1 - 9.3 6.5 11.3 14 6.0 0.2 2.7 2 1 0 2 2 2 0 Haemolysin XhlA Tho2 PF11262.8 KII93108.1 - 9.9 5.3 11.3 22 4.1 11.1 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FdhE PF04216.12 KII93109.1 - 0.012 15.5 1.3 0.022 14.7 1.3 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation TPR_16 PF13432.6 KII93109.1 - 0.16 12.6 0.0 0.16 12.6 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SPESP1 PF15754.5 KII93109.1 - 0.16 11.1 0.3 0.46 9.6 0.3 1.7 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Cohesin_load PF10345.9 KII93109.1 - 0.28 9.6 0.5 1.7 7.0 0.1 2.0 2 0 0 2 2 2 0 Cohesin loading factor PGAP1 PF07819.13 KII93110.1 - 3.6e-07 30.2 0.1 6.6e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KII93110.1 - 4.2e-05 23.3 0.4 0.00043 20.0 0.2 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93110.1 - 0.00041 21.0 3.3 0.00041 21.0 3.3 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KII93110.1 - 0.00065 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KII93110.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 KII93110.1 - 0.0083 15.5 0.0 0.035 13.4 0.0 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 KII93110.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KII93110.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KII93110.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Nse4_C PF08743.10 KII93112.1 - 4e-30 103.9 0.0 8.9e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KII93112.1 - 3.2e-14 52.8 1.9 8.2e-14 51.5 1.9 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Metalloenzyme PF01676.18 KII93114.1 - 3.5e-76 255.8 0.4 4e-76 255.6 0.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KII93114.1 - 8.6e-75 250.9 0.0 1.5e-74 250.1 0.0 1.4 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.23 KII93114.1 - 1.9e-06 27.5 0.4 5.3e-05 22.8 0.1 2.7 2 1 0 2 2 2 1 Sulfatase Alk_phosphatase PF00245.20 KII93114.1 - 0.00092 18.3 0.3 0.006 15.6 0.2 2.1 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.12 KII93114.1 - 0.0016 18.5 0.0 0.0042 17.2 0.0 1.6 2 0 0 2 2 2 1 PglZ domain MFS_1 PF07690.16 KII93115.1 - 2.6e-37 128.6 27.1 2.6e-37 128.6 27.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SecY PF00344.20 KII93115.1 - 0.14 11.4 10.8 0.29 10.4 10.0 2.1 1 1 0 1 1 1 0 SecY translocase F-box-like PF12937.7 KII93116.1 - 3.9e-06 26.6 3.1 4.3e-06 26.5 0.8 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII93116.1 - 0.04 14.4 1.2 3.3 8.3 0.0 4.1 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII93116.1 - 0.15 11.9 0.3 51 3.7 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat F-box PF00646.33 KII93116.1 - 1.7 8.6 6.2 0.26 11.2 0.9 2.5 3 0 0 3 3 3 0 F-box domain Polysacc_deac_1 PF01522.21 KII93119.1 - 0.0013 18.6 0.3 0.0058 16.5 0.1 2.2 2 1 0 2 2 2 1 Polysaccharide deacetylase tRNA-synt_His PF13393.6 KII93120.1 - 5.4e-40 137.6 0.6 1.3e-35 123.2 0.0 2.4 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KII93120.1 - 3.2e-10 40.0 0.0 8.6e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KII93120.1 - 0.008 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs DUF5559 PF17714.1 KII93120.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5559) DivIC PF04977.15 KII93120.1 - 0.3 10.9 1.2 0.68 9.7 1.2 1.6 1 0 0 1 1 1 0 Septum formation initiator Ank_5 PF13857.6 KII93121.1 - 2.7e-12 46.7 0.1 9.9e-05 22.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KII93121.1 - 6.4e-12 45.4 0.3 0.00018 21.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KII93121.1 - 1.6e-11 44.5 0.1 4.3e-07 30.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII93121.1 - 2.4e-11 42.8 0.1 0.00017 21.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KII93121.1 - 3.8e-11 43.4 0.1 8.6e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Serglycin PF04360.12 KII93121.1 - 0.081 12.9 0.3 0.11 12.4 0.3 1.2 1 0 0 1 1 1 0 Serglycin SNF2_N PF00176.23 KII93122.1 - 1.4e-66 224.7 0.1 2.9e-66 223.6 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KII93122.1 - 1.4e-38 131.4 0.5 1.4e-38 131.4 0.5 3.5 3 1 1 4 4 4 1 SLIDE HAND PF09110.11 KII93122.1 - 5.2e-32 110.9 0.8 5.2e-32 110.9 0.8 3.8 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 KII93122.1 - 7.1e-18 65.0 0.0 2.7e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII93122.1 - 1.1e-09 38.5 0.0 5.8e-09 36.2 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KII93122.1 - 3.2e-07 29.8 0.0 8.3e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KII93122.1 - 0.00098 18.9 0.3 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 KII93122.1 - 0.0023 18.3 5.4 0.0023 18.3 5.4 4.3 5 0 0 5 5 5 1 DNA-binding domain AAA_14 PF13173.6 KII93122.1 - 0.01 15.9 1.7 0.032 14.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KII93122.1 - 0.96 9.7 3.8 8.8 6.6 0.0 3.8 3 1 0 3 3 3 0 AAA domain F-box-like PF12937.7 KII93123.1 - 2.2e-07 30.7 2.1 5.6e-07 29.3 1.1 2.3 2 1 0 2 2 2 1 F-box-like Med8 PF10232.9 KII93123.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Tax PF02959.16 KII93124.1 - 0.043 13.3 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 HTLV Tax XPG_I PF00867.18 KII93125.1 - 4.7e-16 58.9 0.0 6.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KII93125.1 - 3.9e-06 27.3 0.0 7.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain GDPD_2 PF13653.6 KII93125.1 - 0.073 13.5 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family SMC_N PF02463.19 KII93128.1 - 2.3e-73 246.3 0.1 4.7e-73 245.2 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KII93128.1 - 8.8e-25 87.3 0.1 3.3e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KII93128.1 - 2.4e-10 40.7 14.3 1.6e-05 24.9 0.0 4.8 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KII93128.1 - 2.9e-09 37.1 3.7 2.9e-09 37.1 3.7 3.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KII93128.1 - 1.4e-05 24.7 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NPR2 PF06218.11 KII93128.1 - 0.03 13.1 1.1 0.083 11.6 1.1 1.7 1 0 0 1 1 1 0 Nitrogen permease regulator 2 ABC_tran PF00005.27 KII93128.1 - 0.96 10.0 0.0 0.96 10.0 0.0 5.5 4 3 0 4 4 4 0 ABC transporter Pkinase PF00069.25 KII93129.1 - 3.2e-39 134.9 0.0 3.8e-38 131.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93129.1 - 8.1e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII93129.1 - 3.5e-05 23.2 0.0 8.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII93129.1 - 6.8e-05 22.9 0.7 0.0023 17.9 0.0 2.8 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KII93129.1 - 0.00023 20.6 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KII93129.1 - 0.00034 19.7 0.0 0.00044 19.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KII93129.1 - 0.0084 14.9 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KII93129.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KII93129.1 - 0.2 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box-like PF12937.7 KII93130.1 - 0.0014 18.5 0.6 0.0051 16.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF2235 PF09994.9 KII93131.1 - 4.8e-79 265.7 0.4 5.8e-79 265.4 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KII93131.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DEAD PF00270.29 KII93132.1 - 0.00088 19.1 0.0 0.0017 18.2 0.0 1.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase TIR-like PF10137.9 KII93132.1 - 0.0059 16.6 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain Fungal_trans PF04082.18 KII93133.1 - 2.2e-20 72.8 1.4 4.2e-20 71.9 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII93133.1 - 0.00091 19.3 14.8 0.0018 18.4 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ImcF-related_N PF14331.6 KII93133.1 - 0.028 13.8 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF4094 PF13334.6 KII93133.1 - 2 8.9 4.6 0.49 10.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) HMGL-like PF00682.19 KII93134.1 - 3.1e-41 141.7 0.0 3.7e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like CDP-OH_P_transf PF01066.21 KII93135.1 - 1.8e-17 63.8 0.0 1.8e-17 63.8 0.0 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box-like PF12937.7 KII93136.1 - 0.0021 17.9 0.3 0.016 15.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 KII93138.1 - 1.3e-06 28.2 4.0 3.3e-06 26.9 1.3 2.7 2 1 0 2 2 2 1 F-box-like Homeodomain PF00046.29 KII93140.1 - 1.8e-15 56.5 2.3 3.3e-15 55.7 2.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII93140.1 - 0.0086 16.0 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Tudor_FRX1 PF18336.1 KII93140.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain F-box-like PF12937.7 KII93141.1 - 9.2e-05 22.3 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like Biotin_lipoyl_2 PF13533.6 KII93141.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Biotin-lipoyl like F-box-like PF12937.7 KII93142.1 - 7.1e-07 29.0 0.1 2.2e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 F-box-like FliD_C PF07195.12 KII93142.1 - 0.011 15.2 1.4 0.017 14.6 1.4 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Allexi_40kDa PF05549.11 KII93142.1 - 0.02 14.4 2.7 1.1 8.7 0.5 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein FliT PF05400.13 KII93142.1 - 0.029 15.2 2.2 0.066 14.0 2.2 1.6 1 0 0 1 1 1 0 Flagellar protein FliT KfrA_N PF11740.8 KII93142.1 - 0.053 14.2 3.7 0.095 13.4 3.7 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Tropomyosin_1 PF12718.7 KII93142.1 - 0.091 12.9 5.8 0.2 11.8 5.8 1.5 1 0 0 1 1 1 0 Tropomyosin like NEMO PF11577.8 KII93142.1 - 0.093 12.8 2.1 0.21 11.6 2.1 1.6 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO C5HCH PF17982.1 KII93142.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain HALZ PF02183.18 KII93142.1 - 0.48 10.7 6.9 2.4 8.4 0.2 3.2 1 1 1 3 3 3 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KII93142.1 - 0.49 10.6 8.7 0.9 9.8 1.9 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 KII93142.1 - 1.9 8.6 8.1 2.1 8.5 2.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 KII93142.1 - 2 8.2 7.0 1.3 8.8 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator Rx_N PF18052.1 KII93143.1 - 0.6 10.4 5.8 4.5 7.6 0.1 3.6 3 1 0 3 3 3 0 Rx N-terminal domain HlyD_2 PF12700.7 KII93143.1 - 3.2 6.4 5.4 0.8 8.4 0.5 2.1 2 0 0 2 2 2 0 HlyD family secretion protein HIP1_clath_bdg PF16515.5 KII93143.1 - 5.1 7.8 18.6 0.15 12.7 2.7 3.4 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Putative_PNPOx PF01243.20 KII93145.1 - 1.4e-08 34.8 0.0 4.8e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Laminin_II PF06009.12 KII93146.1 - 0.013 15.5 8.5 0.02 14.9 8.5 1.3 1 0 0 1 1 1 0 Laminin Domain II Myosin_tail_1 PF01576.19 KII93146.1 - 0.014 13.2 1.9 0.019 12.8 1.9 1.0 1 0 0 1 1 1 0 Myosin tail XhlA PF10779.9 KII93146.1 - 5.1 7.4 7.2 1.7 8.9 3.7 1.9 1 1 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.12 KII93146.1 - 7.5 7.1 17.6 0.65 10.5 9.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CBM_21 PF03370.13 KII93147.1 - 8.2e-16 58.2 0.0 1.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KII93147.1 - 0.00011 22.8 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) BSP_II PF05432.11 KII93148.1 - 1.9 8.1 11.8 2.9 7.5 11.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Trypan_PARP PF05887.11 KII93149.1 - 0.23 11.4 9.2 0.45 10.5 9.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SMBP PF16785.5 KII93149.1 - 0.29 11.4 5.9 5.7 7.2 6.1 2.2 1 1 1 2 2 2 0 Small metal-binding protein Pinin_SDK_memA PF04696.13 KII93149.1 - 0.37 10.8 8.4 0.77 9.8 8.4 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region NAM-associated PF14303.6 KII93149.1 - 0.41 11.4 8.0 1.5 9.6 8.0 2.0 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain F-box-like PF12937.7 KII93150.1 - 3.4e-07 30.1 0.2 1.4e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 F-box-like MaoC_dehydratas PF01575.19 KII93150.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Homeodomain PF00046.29 KII93151.1 - 6.1e-14 51.6 1.3 9.5e-14 51.0 1.3 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII93151.1 - 0.00023 21.0 0.2 0.00043 20.1 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain adh_short PF00106.25 KII93152.1 - 4.3e-24 85.0 0.2 5.5e-24 84.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII93152.1 - 1.8e-21 76.8 0.9 2.2e-21 76.5 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII93152.1 - 2.8e-06 27.4 0.0 3.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KII93152.1 - 0.0094 15.9 0.3 0.11 12.4 0.2 2.1 1 1 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.6 KII93152.1 - 0.014 15.3 2.9 0.019 14.8 2.9 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Methyltransf_16 PF10294.9 KII93153.1 - 6e-18 65.2 0.0 8.9e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KII93153.1 - 9.1e-09 35.1 0.1 1.3e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KII93153.1 - 2e-07 31.6 0.0 5.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93153.1 - 0.00021 22.0 0.0 0.00041 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII93153.1 - 0.00034 20.2 0.1 0.00055 19.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KII93153.1 - 0.00086 19.9 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII93153.1 - 0.0051 16.6 0.0 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KII93153.1 - 0.0055 16.4 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 KII93153.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 KII93155.1 - 9.5e-163 542.3 2.6 1.1e-162 542.1 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KII93155.1 - 0.028 14.4 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) adh_short PF00106.25 KII93156.1 - 4e-43 147.1 0.0 5e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII93156.1 - 1.9e-31 109.4 0.0 2.6e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII93156.1 - 2e-09 37.6 0.4 2.7e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII93156.1 - 4.6e-05 22.9 0.0 6.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KII93156.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pyr_redox_2 PF07992.14 KII93158.1 - 1.2e-26 93.7 0.6 1.5e-26 93.3 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII93158.1 - 1.5e-10 41.5 1.3 3.9e-08 33.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KII93158.1 - 0.00055 19.9 0.6 0.12 12.4 0.0 3.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 KII93158.1 - 8.6 5.8 12.8 0.68 9.5 0.1 3.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase Methyltransf_25 PF13649.6 KII93159.1 - 3.8e-15 56.4 0.0 9.6e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII93159.1 - 5e-13 49.5 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII93159.1 - 7.1e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KII93159.1 - 9.8e-08 32.0 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93159.1 - 6.9e-07 29.9 0.0 1.3e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KII93159.1 - 1.4e-06 27.8 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII93159.1 - 2.2e-06 27.6 0.0 6.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KII93159.1 - 0.00046 19.7 0.0 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KII93159.1 - 0.0021 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KII93159.1 - 0.0063 15.1 0.0 0.012 14.2 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 KII93159.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KII93159.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase FtsJ PF01728.19 KII93159.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase RAP1 PF07218.11 KII93159.1 - 0.37 9.0 3.6 0.5 8.6 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vta1 PF04652.16 KII93162.1 - 2.3e-42 144.4 0.0 3e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KII93162.1 - 1e-14 53.9 0.1 1e-14 53.9 0.1 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain UVR PF02151.19 KII93162.1 - 0.61 9.9 2.0 1.1 9.0 2.0 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif Nop52 PF05997.12 KII93163.1 - 8.1e-78 261.1 0.0 1.2e-77 260.5 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KII93163.1 - 3.8e-06 26.7 0.0 8.1e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 KII93163.1 - 0.14 12.3 0.1 0.63 10.2 0.1 2.1 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Transthyretin PF00576.21 KII93164.1 - 1.4e-35 122.3 0.0 1.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF4198 PF10670.9 KII93164.1 - 0.13 12.6 0.0 0.43 10.9 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4198) UQ_con PF00179.26 KII93165.1 - 4.4e-39 133.3 0.0 5.6e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KII93165.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain adh_short_C2 PF13561.6 KII93166.1 - 1.6e-48 165.4 0.0 1.8e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII93166.1 - 2.8e-33 115.1 0.0 3.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII93166.1 - 1e-07 32.0 0.1 1.5e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII93166.1 - 1.1e-05 25.0 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KII93166.1 - 0.062 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cyt-b5 PF00173.28 KII93167.1 - 1.3e-12 47.6 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIOX_N PF14226.6 KII93168.1 - 0.00019 22.2 0.0 0.00044 21.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII93168.1 - 0.00095 19.6 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 KII93169.1 - 0.00088 19.1 0.1 0.0045 16.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like MMR_HSR1 PF01926.23 KII93170.1 - 1.2e-14 54.3 0.0 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII93170.1 - 3.4e-06 26.7 0.0 7.7e-06 25.5 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KII93170.1 - 0.00028 20.8 0.0 0.006 16.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KII93170.1 - 0.0084 16.2 0.4 0.053 13.6 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 KII93170.1 - 0.2 11.0 0.0 0.41 10.0 0.0 1.4 2 0 0 2 2 2 0 AIG1 family RNA_pol_Rpc4 PF05132.14 KII93170.1 - 0.45 10.9 5.1 0.91 9.9 1.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pyr_redox_2 PF07992.14 KII93171.1 - 6.6e-29 101.1 0.3 8.6e-29 100.7 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KII93171.1 - 8.1e-11 42.3 0.5 4e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KII93171.1 - 0.00044 19.9 7.4 0.044 13.4 0.1 3.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII93171.1 - 0.0011 18.9 0.4 0.15 12.0 0.1 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Malic_M PF03949.15 KII93171.1 - 0.0016 17.8 0.3 0.065 12.5 0.0 2.3 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain K_oxygenase PF13434.6 KII93171.1 - 0.0017 17.6 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 KII93171.1 - 0.0021 18.3 0.7 2.2 8.6 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.14 KII93171.1 - 0.023 13.5 1.8 0.1 11.4 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase DUF4147 PF13660.6 KII93171.1 - 0.026 14.1 0.1 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) NAD_binding_7 PF13241.6 KII93171.1 - 0.039 14.4 0.1 9.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KII93171.1 - 0.044 13.0 4.8 0.41 9.9 0.2 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KII93171.1 - 0.049 12.7 2.2 1.6 7.7 0.1 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KII93171.1 - 0.37 10.0 2.7 2.1 7.5 0.1 2.6 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 KII93171.1 - 4.3 6.3 7.6 14 4.6 0.1 3.1 3 1 0 3 3 3 0 Glucose inhibited division protein A WD40 PF00400.32 KII93174.1 - 1.2e-20 73.4 4.4 0.0014 19.4 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII93174.1 - 4.3e-07 30.1 0.0 0.017 15.4 0.0 4.7 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KII93174.1 - 0.025 14.5 2.3 1.1 9.3 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Homeodomain PF00046.29 KII93175.1 - 1.8e-16 59.7 0.8 3.4e-16 58.8 0.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII93175.1 - 0.0077 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Arrestin_C PF02752.22 KII93176.1 - 4.7e-05 23.9 0.0 9.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain RabGAP-TBC PF00566.18 KII93180.1 - 6.7e-31 107.6 0.0 1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KII93180.1 - 0.17 10.1 4.4 0.029 12.6 0.3 1.6 2 0 0 2 2 2 0 SBE2, cell-wall formation GCP_C_terminal PF04130.13 KII93181.1 - 2.7e-27 96.0 0.0 4.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KII93181.1 - 4.5e-24 85.6 0.0 3e-22 79.6 0.0 2.3 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Ribosomal_S28e PF01200.18 KII93183.1 - 2.1e-32 110.9 1.7 2.3e-32 110.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.20 KII93184.1 - 2e-13 50.5 0.0 9.3e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KII93184.1 - 0.00026 20.4 0.0 0.00037 20.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_24 PF18404.1 KII93184.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 Peptidase_M22 PF00814.25 KII93185.1 - 4.7e-84 282.3 0.0 5.5e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KII93185.1 - 0.0087 15.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus Glyco_hydro_28 PF00295.17 KII93186.1 - 3.1e-40 138.2 4.9 4.4e-40 137.7 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Plavaka PF18759.1 KII93190.1 - 5.4e-46 157.3 0.0 7.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Eno-Rase_FAD_bd PF07055.12 KII93190.1 - 0.091 13.2 3.8 0.95 9.9 1.6 2.6 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain WCCH PF03716.14 KII93190.1 - 0.15 11.8 1.6 0.38 10.5 1.6 1.6 1 0 0 1 1 1 0 WCCH motif Aminotran_1_2 PF00155.21 KII93192.1 - 6.2e-90 302.0 0.0 7.1e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Sigma70_r3 PF04539.16 KII93193.1 - 0.025 14.7 0.1 0.061 13.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70 region 3 FeoC PF09012.10 KII93193.1 - 0.083 13.0 0.1 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator Phage_1_1 PF08200.11 KII93193.1 - 0.088 13.2 2.8 0.49 10.9 2.8 2.4 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein TipAS PF07739.13 KII93193.1 - 0.53 10.8 4.8 2.1 8.9 0.2 3.1 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain KDZ PF18758.1 KII93196.1 - 2.3e-81 272.7 0.0 4.6e-81 271.7 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF3699 PF12480.8 KII93196.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) zf_C2H2_10 PF18414.1 KII93196.1 - 0.35 10.4 1.4 0.84 9.2 1.4 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger Cyclin_C_2 PF16899.5 KII93198.1 - 7.2e-24 84.2 0.3 5.3e-21 74.9 0.0 2.5 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KII93198.1 - 8.9e-11 41.6 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KII93198.1 - 0.00022 21.2 0.0 0.0062 16.6 0.0 2.9 3 0 0 3 3 3 1 Transcription factor TFIIB repeat AAA_18 PF13238.6 KII93200.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KII93200.1 - 1.8e-06 28.4 0.0 3.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KII93200.1 - 0.00021 21.4 0.1 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KII93200.1 - 0.00032 20.6 0.1 0.27 11.1 0.0 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 KII93200.1 - 0.00087 19.6 0.0 0.0021 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KII93200.1 - 0.0012 19.3 0.0 0.0022 18.4 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KII93200.1 - 0.002 18.4 0.1 0.0051 17.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KII93200.1 - 0.0026 17.2 0.9 0.73 9.1 0.1 2.3 2 1 0 2 2 2 2 KaiC ADK PF00406.22 KII93200.1 - 0.0051 16.9 0.0 0.087 12.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase MeaB PF03308.16 KII93200.1 - 0.018 14.0 0.9 0.15 11.0 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KII93200.1 - 0.019 14.5 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KII93200.1 - 0.019 14.9 0.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 KII93200.1 - 0.023 14.4 0.1 5.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 KII93200.1 - 0.03 14.7 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 KII93200.1 - 0.041 13.1 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KII93200.1 - 0.059 13.1 0.0 0.072 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KII93200.1 - 0.071 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KII93200.1 - 0.072 13.1 0.0 0.48 10.5 0.0 1.9 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII93200.1 - 0.085 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 KII93200.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 KII93200.1 - 0.14 11.9 0.1 0.49 10.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KII93200.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 KII93200.1 - 0.18 12.1 0.3 0.44 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain Spt5-NGN PF03439.13 KII93202.1 - 1.9e-22 78.9 0.0 4.4e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KII93202.1 - 1.9e-17 64.1 12.6 1.9e-17 64.1 12.6 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KII93202.1 - 9.9e-16 57.1 21.8 4.5e-06 26.4 0.1 7.1 7 0 0 7 7 7 5 KOW motif CTD PF12815.7 KII93202.1 - 2.8e-11 43.8 54.9 4e-09 36.9 17.7 3.6 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 O-FucT PF10250.9 KII93203.1 - 5e-13 49.5 0.0 1.7e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.7 KII93204.1 - 1.8e-07 30.9 0.3 1.8e-07 30.9 0.3 2.3 3 0 0 3 3 3 1 F-box-like Mu-like_Com PF10122.9 KII93204.1 - 0.02 14.3 0.1 0.39 10.2 0.0 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com F-box-like_2 PF13013.6 KII93204.1 - 0.3 11.1 2.0 1.2 9.1 0.8 2.7 3 1 0 3 3 3 0 F-box-like domain LIAS_N PF16881.5 KII93206.1 - 1.2e-24 86.8 0.0 4.1e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KII93206.1 - 5.2e-14 53.0 0.0 1e-13 52.0 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily JAB PF01398.21 KII93207.1 - 1.4e-14 54.1 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KII93207.1 - 0.0042 17.2 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DPBB_1 PF03330.18 KII93208.1 - 9.8e-09 35.4 0.1 1.1e-08 35.2 0.1 1.2 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KII93208.1 - 0.039 13.8 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Barwin family Ipi1_N PF12333.8 KII93209.1 - 4.7e-22 78.5 0.0 2.2e-20 73.1 0.0 3.2 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation GRIP PF01465.20 KII93210.1 - 9.2e-17 60.7 0.6 3e-16 59.1 0.6 2.0 1 0 0 1 1 1 1 GRIP domain HIP1_clath_bdg PF16515.5 KII93210.1 - 0.014 16.0 7.0 0.014 16.0 7.0 7.4 3 1 4 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 KII93210.1 - 2.7 8.4 80.6 0.042 14.3 24.1 5.2 1 1 4 5 5 5 0 Fez1 Filament PF00038.21 KII93210.1 - 4.6 6.7 73.0 4.2 6.9 11.8 4.0 1 1 3 4 4 4 0 Intermediate filament protein Arrestin_C PF02752.22 KII93211.1 - 0.12 12.9 2.1 0.27 11.7 2.1 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Ras PF00071.22 KII93212.1 - 3.6e-55 186.0 0.0 4.4e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII93212.1 - 1.6e-33 115.5 0.0 2.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII93212.1 - 3.1e-14 52.8 0.0 1.3e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII93212.1 - 3.2e-06 26.7 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII93212.1 - 7.7e-06 25.6 0.0 9.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KII93212.1 - 5.9e-05 23.1 0.0 0.00013 22.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KII93212.1 - 0.0007 20.0 0.1 0.001 19.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain MRI PF15325.6 KII93212.1 - 0.05 14.7 2.3 0.086 13.9 2.3 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection RsgA_GTPase PF03193.16 KII93212.1 - 0.16 11.8 0.1 7.7 6.4 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase Abhydrolase_1 PF00561.20 KII93213.1 - 1.3e-17 64.3 1.1 6.4e-17 62.0 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93213.1 - 5.9e-15 56.5 4.3 9.4e-15 55.8 4.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII93213.1 - 4.3e-11 42.5 0.1 9.7e-11 41.4 0.1 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KII93213.1 - 0.0025 17.4 0.0 0.0078 15.8 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 KII93213.1 - 0.0088 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KII93213.1 - 0.011 14.7 0.0 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme AXE1 PF05448.12 KII93213.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KII93214.1 - 4.1e-17 62.7 0.8 1.1e-16 61.2 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93214.1 - 7.1e-15 56.2 2.1 1.1e-14 55.6 2.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII93214.1 - 8.2e-09 35.1 0.0 2.1e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KII93214.1 - 0.0024 17.5 0.0 0.0076 15.8 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 KII93214.1 - 0.02 13.8 0.0 0.051 12.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KII93214.1 - 0.06 12.3 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase tRNA-synt_2 PF00152.20 KII93215.1 - 2.4e-74 250.3 0.0 3.1e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KII93215.1 - 0.0022 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KII93215.1 - 0.03 13.8 0.2 1 8.8 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Abhydrolase_1 PF00561.20 KII93216.1 - 1.9e-16 60.5 0.2 1.2e-15 57.9 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93216.1 - 3.2e-16 60.6 0.1 4.3e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII93216.1 - 2.9e-08 33.3 0.0 8.9e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KII93216.1 - 0.026 13.2 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 KII93216.1 - 0.047 12.6 0.0 0.92 8.4 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme DLH PF01738.18 KII93216.1 - 0.092 12.3 0.0 0.5 9.9 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 KII93216.1 - 0.096 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Pil1 PF13805.6 KII93217.1 - 2.5e-47 161.6 1.5 3.7e-47 161.1 1.5 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 IF4E PF01652.18 KII93218.1 - 1.8e-47 161.1 0.0 3.1e-47 160.3 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E CBS PF00571.28 KII93219.1 - 3.3e-24 85.1 3.5 7.6e-10 39.1 0.1 4.7 4 1 0 4 4 4 4 CBS domain DEAD PF00270.29 KII93221.1 - 3.2e-15 56.4 0.0 4.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII93221.1 - 9e-10 38.8 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KII93221.1 - 0.0007 19.4 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII93221.1 - 0.0045 17.3 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain FAM176 PF14851.6 KII93222.1 - 5.9 6.5 7.2 0.35 10.5 0.9 2.0 2 0 0 2 2 2 0 FAM176 family SPRY PF00622.28 KII93223.1 - 7.7e-18 64.7 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain TMEM215 PF15746.5 KII93224.1 - 0.014 14.8 0.5 0.026 14.0 0.5 1.4 1 0 0 1 1 1 0 TMEM215 family Mucin PF01456.17 KII93224.1 - 0.02 14.9 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP17 PF15807.5 KII93224.1 - 0.049 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF347 PF03988.12 KII93224.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SMN PF06003.12 KII93228.1 - 1.7e-07 30.8 10.5 6.3e-07 28.9 10.2 1.8 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) RRP36 PF06102.12 KII93228.1 - 0.00011 22.2 6.4 0.00011 22.2 6.4 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 TUDOR PF00567.24 KII93228.1 - 0.0002 21.3 0.0 0.00055 19.9 0.0 1.7 1 1 1 2 2 2 1 Tudor domain Tudor_3 PF18115.1 KII93228.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TSSC4 PF15264.6 KII93228.1 - 0.0083 16.4 1.3 0.018 15.3 1.3 1.6 1 0 0 1 1 1 1 Tumour suppressing sub-chromosomal transferable candidate 4 PWWP PF00855.17 KII93228.1 - 0.012 16.0 2.6 0.17 12.3 2.6 2.5 1 1 0 1 1 1 0 PWWP domain T3SS_needle_reg PF09025.10 KII93228.1 - 0.44 10.5 4.4 0.22 11.5 1.3 2.0 3 0 0 3 3 3 0 YopR, type III needle-polymerisation regulator Jak1_Phl PF17887.1 KII93228.1 - 0.98 9.4 7.3 0.33 10.9 4.4 1.8 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Connexin PF00029.19 KII93228.1 - 1.1 9.0 2.7 1.7 8.4 2.7 1.3 1 0 0 1 1 1 0 Connexin DUF2203 PF09969.9 KII93228.1 - 1.8 9.3 7.5 16 6.2 2.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PDCD2_C PF04194.13 KII93228.1 - 2.2 8.3 8.3 0.78 9.8 4.9 1.8 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain DNA_pol_delta_4 PF04081.13 KII93228.1 - 3.3 8.0 11.0 0.57 10.5 6.9 1.7 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 RR_TM4-6 PF06459.12 KII93228.1 - 6.7 6.4 12.0 0.73 9.6 7.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1764 PF08576.10 KII93229.1 - 1.7e-12 48.1 10.8 4e-09 37.3 1.8 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ribosomal_60s PF00428.19 KII93229.1 - 0.017 15.7 12.2 0.12 13.0 3.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ARID PF01388.21 KII93230.1 - 9.2e-16 58.3 0.0 2.2e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KII93230.1 - 3.4e-08 33.1 0.5 0.00075 18.9 0.1 2.3 2 0 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa Hanta_G1 PF01567.16 KII93230.1 - 0.32 9.7 0.0 0.46 9.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Cation_efflux PF01545.21 KII93231.1 - 4.4e-52 176.7 5.2 7.5e-52 176.0 5.2 1.4 1 1 0 1 1 1 1 Cation efflux family bMG1 PF17970.1 KII93231.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain DUF2157 PF09925.9 KII93231.1 - 1.1 9.1 8.0 0.7 9.7 0.4 2.9 2 2 1 3 3 3 0 Predicted membrane protein (DUF2157) Med5 PF08689.10 KII93232.1 - 1.4e-16 59.6 0.0 4.3e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Mediator complex subunit Med5 Abhydrolase_1 PF00561.20 KII93233.1 - 1.4e-15 57.7 0.1 4.8e-13 49.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93233.1 - 3.1e-13 50.8 0.2 4.5e-13 50.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII93233.1 - 8.2e-09 35.1 0.0 4.6e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KII93233.1 - 0.017 14.7 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Sin_N PF04801.13 KII93234.1 - 1e-21 77.7 0.0 1.3e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region GH131_N PF18271.1 KII93236.1 - 1.8e-58 198.3 0.0 2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain LIM PF00412.22 KII93239.1 - 6.7e-14 51.9 14.9 3.3e-06 27.2 1.8 5.1 6 1 0 6 6 6 3 LIM domain DnaJ PF00226.31 KII93241.1 - 2.1e-19 69.4 0.5 2.1e-19 69.4 0.5 1.6 2 0 0 2 2 2 1 DnaJ domain Gly-zipper_YMGG PF13441.6 KII93241.1 - 0.016 14.9 18.2 0.32 10.8 3.7 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KII93241.1 - 1.1 9.4 23.1 1 9.4 10.6 2.5 2 1 0 2 2 2 0 Glycine zipper Bacteriocin_IIc PF10439.9 KII93241.1 - 1.3 9.2 16.0 3.4 7.9 6.8 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 KII93241.1 - 8.1 6.7 10.2 0.11 12.8 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) F-box-like PF12937.7 KII93242.1 - 1.4e-07 31.3 0.6 4.5e-07 29.6 0.6 2.0 1 0 0 1 1 1 1 F-box-like BRCT_2 PF16589.5 KII93243.1 - 8.5e-12 45.3 0.0 1.1e-05 25.7 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KII93243.1 - 1.4e-09 38.0 2.0 4.6e-09 36.3 2.0 1.9 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KII93243.1 - 4 8.1 6.7 5.2 7.7 4.0 2.6 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.25 KII93244.1 - 2.8e-67 226.9 0.0 3.3e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93244.1 - 1.7e-26 93.1 0.0 2e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII93244.1 - 5.2e-06 26.0 0.1 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KII93244.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KII93244.1 - 0.21 10.5 0.0 0.48 9.3 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain zf-CSL PF05207.13 KII93245.1 - 6.6e-13 48.2 1.1 8.9e-13 47.8 1.1 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KII93245.1 - 9e-13 48.1 0.1 1.2e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Cmc1 PF08583.10 KII93247.1 - 1.9e-11 43.8 0.6 2.3e-11 43.6 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PEX11 PF05648.14 KII93248.1 - 1.1e-50 172.2 0.5 1.2e-50 172.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lyase_1 PF00206.20 KII93250.1 - 1.1e-120 402.7 0.0 1.5e-120 402.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KII93250.1 - 8.4e-20 70.9 0.1 1.9e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus G-alpha PF00503.20 KII93250.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SNF2_N PF00176.23 KII93253.1 - 2.4e-63 214.0 1.6 4.8e-63 213.0 1.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KII93253.1 - 5.9e-48 162.6 21.6 5.9e-48 162.6 21.6 2.4 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 KII93253.1 - 2.4e-16 60.1 0.0 6e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII93253.1 - 9.2e-08 32.3 0.0 3.2e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KII93253.1 - 5.7e-05 22.4 0.3 0.00026 20.3 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PhoH PF02562.16 KII93253.1 - 0.076 12.5 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein HA2 PF04408.23 KII93254.1 - 1.4e-16 60.7 0.3 4.4e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KII93254.1 - 4.1e-14 52.9 0.0 1.3e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KII93254.1 - 1.4e-10 41.4 0.0 2.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KII93254.1 - 4.9e-06 26.9 0.1 1.5e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KII93254.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 KII93254.1 - 0.025 15.1 0.0 0.094 13.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KII93254.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 KII93254.1 - 0.16 11.9 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Ribosomal_L22e PF01776.17 KII93255.1 - 4.8e-46 155.6 0.2 6.1e-46 155.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 KII93255.1 - 0.034 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DKCLD PF08068.12 KII93256.1 - 4.2e-33 113.2 0.2 2.5e-32 110.7 0.3 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KII93256.1 - 3e-23 82.8 0.4 1.2e-19 71.2 0.4 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KII93256.1 - 3.1e-22 78.5 0.8 6.1e-22 77.5 0.8 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KII93256.1 - 1.5e-21 76.1 1.4 3.6e-21 74.9 1.4 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KII93256.1 - 0.015 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SRP-alpha_N PF04086.13 KII93256.1 - 0.7 9.8 20.2 1.1 9.1 20.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.12 KII93256.1 - 0.79 10.0 7.8 1.2 9.4 7.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Copper-bind PF00127.20 KII93257.1 - 3.5e-05 24.2 0.5 0.038 14.4 0.2 2.4 2 0 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 KII93257.1 - 0.0013 18.8 0.1 0.5 10.5 0.0 2.6 2 1 0 2 2 2 2 Cupredoxin-like domain Cu_bind_like PF02298.17 KII93257.1 - 0.038 14.0 0.5 11 6.1 0.4 2.9 2 1 0 2 2 2 0 Plastocyanin-like domain Form-deh_trans PF09163.11 KII93257.1 - 2.5 7.9 9.6 0.31 10.8 0.3 2.5 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Pkinase PF00069.25 KII93258.1 - 1.1e-63 215.1 0.0 1.3e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93258.1 - 1.9e-27 96.2 0.0 3.5e-27 95.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII93258.1 - 9.1e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KII93258.1 - 0.0036 16.7 0.1 0.0063 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KII93258.1 - 0.022 13.7 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KII93258.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KII93258.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 KII93258.1 - 0.16 11.7 0.6 0.33 10.7 0.2 1.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Spc7 PF08317.11 KII93259.1 - 0.00048 19.1 0.8 0.0008 18.4 0.8 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_GP20 PF06810.11 KII93259.1 - 0.0019 18.0 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 HALZ PF02183.18 KII93259.1 - 0.0033 17.6 0.7 0.27 11.5 0.1 2.5 1 1 1 2 2 2 1 Homeobox associated leucine zipper Tmemb_cc2 PF10267.9 KII93259.1 - 0.0052 16.0 0.4 0.0075 15.5 0.4 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein GAS PF13851.6 KII93259.1 - 0.016 14.5 1.6 0.03 13.7 1.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KII93259.1 - 0.016 15.4 3.5 0.042 14.1 3.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 KII93259.1 - 0.02 15.0 5.2 2 8.6 1.9 3.7 2 1 2 4 4 4 0 bZIP transcription factor BLOC1_2 PF10046.9 KII93259.1 - 0.022 15.0 0.3 0.046 14.0 0.3 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 KII93259.1 - 0.052 13.9 2.5 0.54 10.7 2.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 KII93259.1 - 0.054 13.5 2.8 0.13 12.3 2.8 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 KII93259.1 - 0.065 13.3 3.1 0.17 11.9 3.1 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 KII93259.1 - 0.075 13.3 1.2 0.25 11.6 1.2 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 KII93259.1 - 0.086 13.1 2.0 0.2 11.9 2.0 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Prefoldin PF02996.17 KII93259.1 - 0.088 12.7 1.1 0.43 10.5 0.5 2.2 1 1 1 2 2 2 0 Prefoldin subunit TolA_bind_tri PF16331.5 KII93259.1 - 0.11 12.6 1.6 1.1 9.4 0.6 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation CHDCT2 PF08074.11 KII93259.1 - 0.11 12.6 0.6 0.22 11.7 0.6 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Med9 PF07544.13 KII93259.1 - 0.12 12.5 1.4 0.36 10.9 1.0 1.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 KII93259.1 - 0.15 10.6 0.3 0.28 9.7 0.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Adaptin_binding PF10199.9 KII93259.1 - 0.18 12.4 2.1 0.32 11.6 0.1 2.4 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DASH_Dad2 PF08654.10 KII93259.1 - 0.19 12.2 5.4 3.2 8.2 0.3 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 YojJ PF10372.9 KII93259.1 - 0.19 11.8 0.1 0.48 10.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus FUSC PF04632.12 KII93259.1 - 0.24 9.9 3.2 0.38 9.2 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2730 PF10805.8 KII93259.1 - 0.31 11.2 2.0 1.7 8.8 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2046 PF09755.9 KII93259.1 - 0.36 10.0 4.5 0.15 11.3 2.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF1664 PF07889.12 KII93259.1 - 0.37 10.8 1.4 0.87 9.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KII93259.1 - 0.4 11.4 1.5 0.95 10.1 1.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF1192 PF06698.11 KII93259.1 - 1 9.4 4.7 39 4.4 0.4 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) BSP_II PF05432.11 KII93259.1 - 6.2 6.4 9.8 23 4.6 9.9 1.8 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) FMN_dh PF01070.18 KII93260.1 - 3.1e-110 368.5 0.1 3.7e-110 368.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KII93260.1 - 3.3e-20 72.0 0.0 6.2e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KII93260.1 - 0.00036 19.8 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KII93260.1 - 0.0012 17.9 1.1 0.0022 17.0 0.2 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KII93260.1 - 0.0018 17.8 0.8 0.0048 16.3 0.2 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 KII93260.1 - 0.051 12.9 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FAD-oxidase_C PF02913.19 KII93262.1 - 2.2e-52 178.2 0.0 2.6e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KII93262.1 - 1.7e-35 121.8 0.7 2.8e-35 121.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GYF PF02213.16 KII93263.1 - 3.6e-15 55.4 0.1 7.9e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KII93263.1 - 0.051 13.4 0.1 0.15 11.9 0.1 1.8 1 0 0 1 1 1 0 GYF domain 2 AMP-binding PF00501.28 KII93264.1 - 9.5e-78 261.7 0.0 1.1e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII93264.1 - 7.7e-20 71.7 0.1 1.7e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Alginate_lyase PF05426.12 KII93265.1 - 1.4e-49 169.1 1.9 1.6e-47 162.3 0.6 2.4 2 0 0 2 2 2 2 Alginate lyase CPSase_L_D2 PF02786.17 KII93266.1 - 4.9e-73 245.1 0.0 8.2e-73 244.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KII93266.1 - 1.2e-46 157.8 0.4 3.3e-46 156.4 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KII93266.1 - 2.1e-29 101.8 0.0 7.5e-23 80.7 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KII93266.1 - 1.9e-15 56.5 4.7 3.7e-15 55.5 4.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KII93266.1 - 1.4e-08 34.6 0.0 3.7e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KII93266.1 - 2.1e-07 30.7 0.0 5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KII93266.1 - 2e-05 24.3 1.1 0.00071 19.4 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Ntox43 PF15537.6 KII93266.1 - 0.03 14.4 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 43 ATP-grasp_3 PF02655.14 KII93266.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain HlyD_D23 PF16576.5 KII93266.1 - 0.053 12.7 0.8 3 7.0 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 KII93266.1 - 0.082 13.6 0.4 7.2 7.4 0.0 2.6 2 0 0 2 2 2 0 HlyD family secretion protein NQRA PF05896.11 KII93266.1 - 0.24 10.8 0.9 0.42 10.0 0.9 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Exo84_C PF16528.5 KII93267.1 - 3.6e-41 141.2 0.3 3.6e-41 141.2 0.3 2.2 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KII93267.1 - 7.5e-18 64.4 1.5 1.8e-17 63.2 1.5 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KII93267.1 - 2.2e-06 27.8 2.2 6.5e-06 26.3 2.3 1.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 KII93267.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 KII93267.1 - 0.04 13.7 0.4 0.097 12.5 0.4 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sel1 PF08238.12 KII93268.1 - 3.8e-45 151.3 21.3 2.2e-08 34.5 0.2 7.7 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 KII93268.1 - 0.66 10.7 6.5 38 5.2 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat DNA_methylase PF00145.17 KII93270.1 - 1.3e-39 136.5 0.0 3.8e-38 131.7 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KII93270.1 - 1.4e-15 57.2 0.0 9.1e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KII93270.1 - 3e-08 33.8 0.0 6.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Phage_ASH PF10554.9 KII93270.1 - 0.028 14.8 0.1 0.067 13.5 0.1 1.6 1 0 0 1 1 1 0 Ash protein family Pkinase PF00069.25 KII93271.1 - 1.2e-66 224.8 0.0 1.5e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93271.1 - 1.3e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII93271.1 - 7.6e-06 25.1 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KII93271.1 - 0.00075 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII93271.1 - 0.00076 18.9 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII93271.1 - 0.0048 16.3 0.0 0.049 12.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KII93271.1 - 0.014 15.0 0.1 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 KII93271.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NAD_binding_1 PF00175.21 KII93272.1 - 1e-25 90.5 0.0 1.6e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KII93272.1 - 3.2e-18 65.9 0.0 5.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KII93272.1 - 1.3e-06 28.6 0.0 0.002 18.3 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KII93272.1 - 0.0069 16.6 0.0 0.02 15.1 0.0 1.8 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain UCH PF00443.29 KII93273.1 - 3.6e-40 138.1 0.0 1.6e-39 136.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KII93273.1 - 3.4e-23 81.3 2.6 4.3e-17 61.8 0.1 3.3 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KII93273.1 - 7.4e-09 35.6 0.1 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF3450 PF11932.8 KII93277.1 - 0.0028 17.0 0.1 0.0032 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Tropomyosin PF00261.20 KII93277.1 - 0.01 15.2 0.1 0.011 15.1 0.1 1.0 1 0 0 1 1 1 0 Tropomyosin HSBP1 PF06825.12 KII93277.1 - 0.1 12.5 0.9 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MobC PF05713.11 KII93277.1 - 0.12 12.8 0.1 9.3 6.8 0.1 2.4 2 1 1 3 3 3 0 Bacterial mobilisation protein (MobC) efThoc1 PF11957.8 KII93278.1 - 8e-90 301.8 1.3 4.9e-85 286.1 0.3 2.2 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.21 KII93278.1 - 3e-42 144.7 0.0 5.4e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII93278.1 - 1.1e-41 143.4 0.0 1.6e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KII93278.1 - 3.3e-10 39.6 0.2 2e-09 37.0 0.1 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KII93278.1 - 4.6e-09 35.7 0.0 1.3e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KII93278.1 - 1.2e-08 34.5 0.0 5.3e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KII93278.1 - 1.8e-06 28.0 0.0 9.5e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 KR domain DapB_N PF01113.20 KII93278.1 - 0.0017 18.5 0.0 0.0049 17.0 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 KII93278.1 - 0.0035 17.2 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KII93278.1 - 0.0088 15.2 0.0 0.021 14.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KII93278.1 - 0.032 13.7 0.0 0.64 9.4 0.0 2.4 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 KII93278.1 - 0.062 12.8 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family MFS_1 PF07690.16 KII93279.1 - 2.8e-38 131.7 24.8 2.8e-38 131.7 24.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily HTH_Tnp_4 PF13613.6 KII93279.1 - 0.077 12.7 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Hum_adeno_E3A PF05393.11 KII93279.1 - 8.5 6.4 7.5 1 9.4 0.0 3.1 4 1 0 4 4 4 0 Human adenovirus early E3A glycoprotein DUF4246 PF14033.6 KII93280.1 - 5.7e-88 296.0 0.0 6.8e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Rotamase PF00639.21 KII93281.1 - 1.1e-21 77.6 0.0 1.5e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KII93281.1 - 9.4e-18 64.9 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KII93281.1 - 4.9e-07 29.7 0.5 1.6e-06 28.0 0.3 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KII93281.1 - 0.0018 19.1 0.0 0.0028 18.5 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain MOSC PF03473.17 KII93282.1 - 1.8e-23 83.0 0.0 2.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KII93282.1 - 5.8e-16 58.5 0.0 9.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain UCH PF00443.29 KII93283.1 - 1.9e-56 191.4 0.0 2.8e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII93283.1 - 1.4e-29 103.8 0.2 1.5e-21 77.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KII93283.1 - 0.031 13.7 1.4 0.39 10.2 0.8 2.6 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ADH_zinc_N PF00107.26 KII93285.1 - 8.4e-30 103.4 0.0 2e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII93285.1 - 4.4e-21 76.3 0.0 7.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII93285.1 - 5.7e-07 29.4 0.0 2.9e-05 23.9 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KII93285.1 - 0.0083 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ABC_cobalt PF09819.9 KII93285.1 - 0.091 12.9 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component adh_short PF00106.25 KII93286.1 - 8.9e-25 87.3 0.0 1.3e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII93286.1 - 8.1e-23 81.2 0.3 9e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII93286.1 - 4e-06 26.8 0.0 7.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KII93286.1 - 0.0026 17.7 1.8 0.0046 16.9 0.9 2.0 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KII93286.1 - 0.032 13.8 0.4 0.064 12.8 0.4 1.5 1 0 0 1 1 1 0 NmrA-like family Y_phosphatase PF00102.27 KII93287.1 - 3.6e-36 124.9 0.0 4.2e-23 82.1 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KII93287.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate F5_F8_type_C PF00754.25 KII93288.1 - 0.0015 18.7 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 KII93288.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) O-FucT PF10250.9 KII93291.1 - 0.046 13.4 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase MFS_1 PF07690.16 KII93292.1 - 4.9e-49 167.1 21.4 4.9e-49 167.1 21.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII93292.1 - 6.6e-15 54.9 6.8 6.6e-15 54.9 6.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KII93292.1 - 1e-09 37.4 2.4 1.5e-09 36.9 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KII93292.1 - 0.00061 18.5 10.0 0.00061 18.5 10.0 2.5 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KII93292.1 - 0.0011 17.9 0.5 0.0011 17.9 0.5 2.8 1 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KII93292.1 - 0.0012 17.4 6.2 0.0012 17.4 6.2 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.8 KII93292.1 - 0.0024 16.6 0.8 0.0024 16.6 0.8 3.1 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like OATP PF03137.20 KII93292.1 - 0.72 8.1 6.5 1.6 6.9 1.1 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 KII93293.1 - 1.4e-07 31.3 1.9 2.6e-07 30.4 1.9 1.5 1 0 0 1 1 1 1 F-box-like gag-asp_proteas PF13975.6 KII93299.1 - 0.15 12.6 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 KII93299.1 - 0.27 11.1 2.4 0.53 10.2 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.24 KII93300.1 - 7.8e-15 54.5 0.2 8.3e-15 54.4 0.2 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3786 PF12654.7 KII93300.1 - 0.059 13.0 0.0 0.059 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) DUF4413 PF14372.6 KII93301.1 - 0.027 14.8 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) gag-asp_proteas PF13975.6 KII93302.1 - 0.028 15.0 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Transposase_21 PF02992.14 KII93303.1 - 1.5e-06 27.6 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 KII93303.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PUL PF08324.11 KII93303.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 PUL domain zf-C2HC5 PF06221.13 KII93303.1 - 0.16 11.9 2.0 0.42 10.6 2.0 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-MYND PF01753.18 KII93305.1 - 2.2e-09 37.2 11.0 3.9e-09 36.5 11.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII93305.1 - 0.034 14.5 7.7 0.059 13.7 7.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KII93306.1 - 4.4e-09 36.3 10.5 7.9e-09 35.5 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII93306.1 - 0.042 14.1 7.4 0.11 12.9 7.4 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cation_efflux PF01545.21 KII93308.1 - 3.1e-21 76.0 6.3 3.8e-21 75.7 6.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KII93308.1 - 6.6e-12 45.4 0.3 1.3e-11 44.5 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 KII93310.1 - 6.6e-71 238.8 0.0 8.9e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93310.1 - 1.1e-51 175.6 0.0 1.6e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII93310.1 - 1.7e-05 23.8 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII93310.1 - 0.00035 20.0 0.0 0.0052 16.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KII93310.1 - 0.0034 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Haspin_kinase PF12330.8 KII93310.1 - 0.0073 15.3 0.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Adaptin_N PF01602.20 KII93311.1 - 3.1e-111 372.5 0.0 4e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KII93311.1 - 3.9e-13 49.8 0.1 3.3e-10 40.2 0.0 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII93311.1 - 3.7e-07 30.4 4.8 0.013 15.9 0.1 5.2 3 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 KII93311.1 - 3.8e-06 26.7 2.8 0.72 10.3 0.0 5.7 6 1 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 KII93311.1 - 0.00016 21.8 0.6 0.096 12.9 0.0 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 KII93311.1 - 0.0043 17.0 0.7 2.1 8.2 0.0 3.3 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 KII93311.1 - 0.025 15.1 10.5 1.8 9.2 0.0 6.5 6 2 1 7 7 7 0 HEAT-like repeat RabGAP-TBC PF00566.18 KII93312.1 - 1.1e-47 162.5 0.0 1.5e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_H PF00075.24 KII93313.1 - 4.1e-33 114.6 0.0 8e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KII93313.1 - 1.5e-19 70.0 0.9 1.5e-19 70.0 0.9 2.0 2 0 0 2 2 2 1 Caulimovirus viroplasmin NARP1 PF12569.8 KII93315.1 - 3.6 6.4 8.5 3.9 6.3 8.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KII93315.1 - 4.3 6.0 4.6 4.7 5.9 4.6 1.0 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 KII93315.1 - 9.3 4.6 6.9 12 4.2 6.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Zf_RING PF16744.5 KII93318.1 - 0.021 14.9 0.7 0.042 13.9 0.0 1.7 2 0 0 2 2 2 0 KIAA1045 RING finger ING PF12998.7 KII93319.1 - 1.8e-14 54.1 0.2 2.6e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KII93319.1 - 1.5e-05 24.8 8.2 2.5e-05 24.1 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KII93319.1 - 0.13 11.8 3.5 0.24 11.0 3.5 1.4 1 0 0 1 1 1 0 PHD-finger Fip1 PF05182.13 KII93320.1 - 3.6e-21 74.4 0.8 6e-21 73.7 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif Pentapeptide_2 PF01469.18 KII93320.1 - 0.00032 20.5 0.1 0.00032 20.5 0.1 2.5 2 1 0 2 2 2 1 Pentapeptide repeats (8 copies) SOG2 PF10428.9 KII93320.1 - 6.6 5.8 13.5 12 5.0 13.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RIC1 PF07064.13 KII93321.1 - 6.4e-100 333.7 0.2 8.7e-100 333.3 0.2 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KII93321.1 - 0.039 14.3 0.0 0.8 10.0 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PRELI PF04707.14 KII93322.1 - 1e-36 126.1 0.0 1.2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Phage_T4_Ndd PF06591.11 KII93322.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) DUF2370 PF10176.9 KII93323.1 - 4.3e-71 239.2 0.0 5.5e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mpv17_PMP22 PF04117.12 KII93324.1 - 1.5e-23 82.7 0.5 2.3e-23 82.2 0.5 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M48_N PF16491.5 KII93325.1 - 0.0019 18.1 0.6 0.0019 18.1 0.6 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices PIG-P PF08510.12 KII93325.1 - 4.8 7.1 6.1 3.8 7.4 1.4 2.7 2 1 0 2 2 2 0 PIG-P AA_permease PF00324.21 KII93326.1 - 1.5e-127 426.1 33.4 1.9e-127 425.8 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII93326.1 - 7e-35 120.7 37.5 8.4e-35 120.4 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease LPD39 PF18858.1 KII93327.1 - 0.083 13.0 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 RNA_pol_3_Rpc31 PF11705.8 KII93327.1 - 2.1 8.5 7.0 5.5 7.2 7.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Kdo PF06293.14 KII93328.1 - 0.077 12.3 0.1 0.092 12.1 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drc1-Sld2 PF11719.8 KII93329.1 - 0.014 15.0 1.7 0.017 14.7 1.7 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF1179 PF06678.11 KII93329.1 - 0.43 10.6 3.0 0.64 10.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) BNR PF02012.20 KII93331.1 - 6.3e-11 40.6 25.2 1.4 9.2 0.0 9.4 8 0 0 8 8 8 7 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KII93331.1 - 4.7e-09 35.5 10.1 0.0022 16.8 0.0 6.2 6 1 0 7 7 7 4 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 KII93331.1 - 2.6e-06 27.0 4.4 2.1 8.6 0.0 6.1 5 0 0 5 5 5 2 BNR-Asp box repeat LRR_4 PF12799.7 KII93332.1 - 6.8e-13 48.6 5.2 0.0015 18.9 0.0 6.8 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII93332.1 - 8.8e-07 28.6 4.5 0.9 9.3 0.3 5.7 4 1 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KII93332.1 - 0.038 14.0 14.0 2.1 8.6 0.0 6.9 10 0 0 10 10 10 0 Leucine Rich repeat DUF1345 PF07077.11 KII93333.1 - 0.37 10.5 4.1 0.96 9.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) RhoGEF PF00621.20 KII93334.1 - 1.2e-44 152.8 0.0 1.8e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 KII93334.1 - 1.6e-09 37.4 2.9 0.00021 21.0 0.3 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KII93334.1 - 1.8e-06 28.1 4.5 0.023 15.1 0.4 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII93334.1 - 0.049 14.2 1.2 33 5.6 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat NOA36 PF06524.12 KII93334.1 - 0.11 11.8 3.7 0.21 10.9 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3292 PF11696.8 KII93334.1 - 0.49 8.7 1.5 18 3.5 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) PAXNEB PF05625.11 KII93335.1 - 8.5e-62 209.4 0.0 1.1e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 PAXNEB protein Glyco_hydro_100 PF12899.7 KII93335.1 - 0.059 12.0 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Peptidase_S24 PF00717.23 KII93336.1 - 3.9e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KII93336.1 - 1.3e-05 25.0 0.1 0.0077 16.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_2 PF07719.17 KII93337.1 - 2.3e-09 36.6 0.3 0.0026 17.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII93337.1 - 7e-09 35.1 0.9 0.00054 19.7 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII93337.1 - 0.0017 18.6 0.9 0.63 10.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII93337.1 - 0.0032 17.1 0.3 0.032 13.9 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 KII93337.1 - 0.0054 16.7 0.1 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII93337.1 - 0.011 16.4 0.8 0.29 11.8 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KII93337.1 - 0.022 14.9 0.0 0.3 11.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII93337.1 - 0.11 13.3 1.4 2.4 9.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MLP1_2 PF07926.12 KII93337.1 - 3.1 7.9 7.1 0.39 10.8 1.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein adh_short PF00106.25 KII93338.1 - 3.9e-33 114.6 0.0 4.7e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII93338.1 - 6.7e-16 58.6 0.0 9.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII93338.1 - 6.5e-06 26.2 0.0 7.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 KR domain SP24 PF16504.5 KII93338.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus AlaDh_PNT_N PF05222.15 KII93339.1 - 8.5e-28 97.3 0.0 1.3e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KII93339.1 - 0.0015 17.9 0.0 0.0023 17.2 0.0 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-Tim10_DDP PF02953.15 KII93342.1 - 1.8e-23 81.9 1.5 2.1e-23 81.7 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.21 KII93343.1 - 1.3e-22 79.8 0.0 2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KII93343.1 - 5.3e-08 32.9 1.0 4e-07 30.0 0.2 2.2 2 0 0 2 2 2 1 Acyltransferase C-terminus Aa_trans PF01490.18 KII93344.1 - 1.6e-34 119.3 37.2 1.8e-34 119.1 37.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Hydrolase_4 PF12146.8 KII93345.1 - 1.4e-05 24.5 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII93345.1 - 0.023 14.3 2.1 0.05 13.2 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold DAP10 PF07213.11 KII93346.1 - 0.1 12.5 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein TMEM154 PF15102.6 KII93346.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family SPX PF03105.19 KII93346.1 - 6 6.7 7.0 8.2 6.2 7.0 1.3 1 0 0 1 1 1 0 SPX domain Tad PF13400.6 KII93346.1 - 8.9 6.7 7.5 2 8.8 4.0 1.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Septin PF00735.18 KII93349.1 - 2e-108 362.0 0.0 3.4e-108 361.2 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KII93349.1 - 1.7e-06 28.1 0.0 5e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KII93349.1 - 0.00025 21.1 2.1 0.28 11.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KII93349.1 - 0.0068 16.0 0.1 0.22 11.0 0.0 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KII93349.1 - 0.032 13.5 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.18 KII93349.1 - 0.033 13.5 0.1 0.071 12.5 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KII93349.1 - 0.043 13.7 4.3 0.069 13.0 0.5 2.9 3 1 0 3 3 3 0 RsgA GTPase IIGP PF05049.13 KII93349.1 - 0.1 11.6 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 KII93349.1 - 0.12 12.5 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KII93349.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KII93350.1 - 1.9e-108 362.0 0.2 3e-108 361.4 0.0 1.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KII93350.1 - 1.3e-06 28.5 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII93350.1 - 0.0006 19.4 0.1 0.031 13.8 0.1 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII93350.1 - 0.0018 18.2 0.8 0.032 14.1 0.5 2.8 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KII93350.1 - 0.0081 16.2 1.4 2.3 8.2 0.0 2.9 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.16 KII93350.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FtsK_SpoIIIE PF01580.18 KII93350.1 - 0.03 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KII93350.1 - 0.055 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KII93350.1 - 0.087 11.9 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KII93350.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gasdermin_C PF17708.1 KII93350.1 - 0.33 11.0 3.7 0.24 11.5 2.1 1.6 2 0 0 2 2 2 0 Gasdermin PUB domain MutS_V PF00488.21 KII93351.1 - 2.4e-69 233.1 0.1 8.5e-69 231.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KII93351.1 - 1.7e-39 136.0 1.2 3.1e-39 135.2 1.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KII93351.1 - 7.2e-23 81.0 0.0 1.6e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KII93351.1 - 1.5e-08 35.0 0.1 5.8e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KII93351.1 - 0.00026 20.7 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KII93351.1 - 0.0047 17.5 0.0 0.036 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII93351.1 - 0.021 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KII93351.1 - 0.17 11.9 0.0 0.62 10.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain HHV-1_VABD PF16852.5 KII93351.1 - 0.7 10.0 2.4 0.73 9.9 0.1 2.3 3 0 0 3 3 3 0 Herpes viral adaptor-to-host cellular mRNA binding domain Aconitase PF00330.20 KII93352.1 - 1e-150 502.8 0.0 1.3e-150 502.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KII93352.1 - 1.5e-34 119.2 0.0 2.5e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KII93352.1 - 0.2 10.3 0.1 0.52 9.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Oxysterol_BP PF01237.18 KII93353.1 - 1.5e-109 366.3 0.1 7.5e-109 364.0 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KII93353.1 - 3e-16 59.5 0.0 1.3e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KII93353.1 - 0.00035 21.0 0.1 0.0023 18.4 0.1 2.3 1 1 0 1 1 1 1 PH domain DUF1840 PF08895.11 KII93353.1 - 6.3 7.2 6.4 0.52 10.7 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Glyco_hydro_3_C PF01915.22 KII93354.1 - 2e-53 181.4 0.0 3.7e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII93354.1 - 2.4e-38 132.3 0.0 4.4e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII93354.1 - 1.3e-21 76.5 0.1 2.4e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pantoate_transf PF02548.15 KII93355.1 - 0.061 12.7 0.0 0.063 12.6 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase 6PGD PF00393.19 KII93358.1 - 8.5e-125 415.9 0.0 1e-124 415.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KII93358.1 - 1.1e-50 171.9 0.0 1.6e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII93358.1 - 0.0018 18.8 0.1 0.0041 17.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KII93358.1 - 0.037 13.7 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoatB PF10389.9 KII93358.1 - 3.9 7.4 5.6 28 4.6 2.0 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B Asn_synthase PF00733.21 KII93359.1 - 1.8e-22 80.5 0.7 2.7e-10 40.4 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KII93359.1 - 5.4e-07 29.6 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 KII93359.1 - 0.027 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.25 KII93360.1 - 4.1e-24 85.5 4.4 7.9e-24 84.6 3.9 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KII93360.1 - 0.0009 18.4 4.8 0.0012 18.0 4.8 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial MgtE_N PF03448.17 KII93360.1 - 0.19 12.4 1.9 6.7 7.4 0.0 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain vATP-synt_E PF01991.18 KII93360.1 - 1.4 8.3 10.2 2.2 7.7 10.2 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit COesterase PF00135.28 KII93361.1 - 4.8e-87 293.0 0.0 2.5e-85 287.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII93361.1 - 0.0044 16.9 0.0 0.028 14.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII93361.1 - 0.049 13.1 0.3 0.21 11.0 0.5 1.7 1 1 1 2 2 2 0 Prolyl oligopeptidase family RRM_1 PF00076.22 KII93362.1 - 4.4e-55 183.4 0.0 2.2e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII93362.1 - 1.8e-08 34.0 0.0 0.00019 21.0 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII93362.1 - 1.8e-06 27.7 0.0 0.0003 20.6 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Cas_Cas2CT1978 PF09707.10 KII93362.1 - 0.0029 17.7 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 KII93362.1 - 0.0082 16.2 0.0 0.17 12.0 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KII93362.1 - 0.031 14.3 0.1 19 5.3 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NAD_binding_10 PF13460.6 KII93363.1 - 1.2e-11 44.9 0.0 5.7e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KII93363.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF2866 PF11065.8 KII93363.1 - 0.012 15.7 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) ApbA PF02558.16 KII93363.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_72 PF03198.14 KII93364.1 - 3e-88 296.1 0.0 4.2e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KII93364.1 - 9.4e-21 74.3 1.6 2.6e-20 72.9 1.6 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KII93364.1 - 0.0025 17.3 0.0 0.026 14.0 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 KII93365.1 - 9.3e-15 54.2 0.1 1.3e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KII93365.1 - 1.5e-08 34.3 1.5 2.5e-08 33.6 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KII93365.1 - 0.00017 21.5 0.3 0.00044 20.1 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KII93365.1 - 0.012 15.3 2.7 0.012 15.3 2.7 2.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KII93365.1 - 0.04 13.7 1.3 0.099 12.5 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KII93365.1 - 0.083 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_3 PF08777.11 KII93365.1 - 0.16 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Nre_N PF04894.12 KII93366.1 - 0.014 15.2 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Archaeal Nre, N-terminal HSP9_HSP12 PF04119.12 KII93366.1 - 0.075 13.4 3.1 0.87 10.0 0.2 2.6 1 1 1 2 2 2 0 Heat shock protein 9/12 Med6 PF04934.14 KII93367.1 - 9.9e-43 145.1 0.1 1.5e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.20 KII93368.1 - 5.4e-44 149.6 0.1 1.3e-43 148.4 0.1 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SGT1 PF07093.11 KII93369.1 - 2e-99 333.7 0.1 2e-99 333.7 0.1 3.6 3 1 0 3 3 3 2 SGT1 protein p450 PF00067.22 KII93370.1 - 2.3e-73 247.5 0.0 4.9e-73 246.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII93371.1 - 6.3e-72 242.8 0.0 1.9e-71 241.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF3674 PF12426.8 KII93371.1 - 0.12 12.5 0.4 0.23 11.5 0.4 1.4 1 0 0 1 1 1 0 RNA dependent RNA polymerase DNA_pol_A_exo1 PF01612.20 KII93373.1 - 2.6e-20 72.9 0.0 2.9e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease Alpha-E PF04168.12 KII93373.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Glyco_hydro_18 PF00704.28 KII93374.1 - 6e-23 82.0 2.2 1.5e-22 80.8 2.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RAP1 PF07218.11 KII93374.1 - 0.29 9.4 7.6 0.39 8.9 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_18 PF00704.28 KII93375.1 - 3.2e-12 46.8 0.1 4.6e-12 46.3 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 KII93376.1 - 2.1e-63 214.1 0.1 2.5e-63 213.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93376.1 - 6.9e-20 71.4 0.0 9.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII93376.1 - 1.4e-07 31.7 0.0 1.7e-05 24.9 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII93376.1 - 0.0036 16.1 0.0 0.0063 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KII93376.1 - 0.024 14.2 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KII93376.1 - 0.038 13.3 0.4 0.068 12.5 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.8 KII93376.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 2 0 0 2 2 2 0 Aconitate B N-terminal domain SET PF00856.28 KII93377.1 - 0.00014 22.3 0.0 0.0039 17.6 0.0 2.2 1 1 0 1 1 1 1 SET domain DnaJ_C PF01556.18 KII93379.1 - 1.3e-30 106.5 0.0 2.7e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.31 KII93379.1 - 2.2e-23 82.2 1.1 3.6e-23 81.5 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KII93379.1 - 8.8e-10 38.8 19.8 1.3e-09 38.3 18.5 1.9 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KII93379.1 - 0.027 14.4 14.8 0.13 12.2 3.0 2.8 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KII93379.1 - 1.1 9.3 4.9 2.7 8.0 4.9 1.7 1 1 0 1 1 1 0 zinc-ribbons MFS_1 PF07690.16 KII93380.1 - 8.9e-43 146.6 53.1 1.2e-31 109.9 35.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII93380.1 - 4.6e-10 38.6 14.8 4.6e-10 38.6 14.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) LRR19-TM PF15176.6 KII93380.1 - 0.6 10.1 1.7 2.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain HlyIII PF03006.20 KII93380.1 - 2.1 8.0 18.3 0.39 10.4 10.3 3.0 1 1 1 2 2 2 0 Haemolysin-III related Choline_kinase PF01633.20 KII93381.1 - 4.2e-50 170.3 0.0 5.7e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KII93381.1 - 2.2e-11 44.2 0.1 3.3e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.24 KII93382.1 - 4.8e-19 67.8 13.9 5.1e-11 42.2 2.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII93382.1 - 5e-09 35.9 13.6 1.5e-06 28.1 3.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KII93382.1 - 8.2e-08 31.9 11.2 6.3e-05 22.7 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KII93382.1 - 0.034 14.6 8.4 0.091 13.3 0.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KII93382.1 - 0.11 13.2 10.0 1 10.1 1.7 3.0 1 1 1 2 2 2 0 Torus domain BLM10_mid PF16507.5 KII93383.1 - 6.3e-186 619.1 0.0 8.9e-186 618.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KII93383.1 - 3e-31 107.2 0.3 1.4e-29 101.9 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KII93383.1 - 1.4e-06 28.0 0.6 0.0051 17.0 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KII93383.1 - 0.00051 20.4 0.2 0.031 14.6 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KII93383.1 - 0.008 16.8 0.4 0.41 11.3 0.0 3.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KII93383.1 - 0.014 15.9 1.7 1.2 9.7 0.1 4.2 3 1 0 3 3 3 0 HEAT-like repeat NopRA1 PF16201.5 KII93383.1 - 0.078 12.6 0.5 19 4.8 0.0 3.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Chalcone_2 PF16035.5 KII93384.1 - 5.7e-29 101.4 0.2 1.4e-17 64.2 0.0 2.4 1 1 0 2 2 2 2 Chalcone isomerase like Histone PF00125.24 KII93385.1 - 3.7e-50 169.7 3.8 4.2e-50 169.5 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KII93385.1 - 2.6e-05 24.5 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KII93385.1 - 5.4e-05 23.3 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KII93385.1 - 0.00051 20.7 2.2 0.00065 20.3 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KII93385.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KII93385.1 - 0.087 12.8 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KII93385.1 - 0.11 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C3HC4_2 PF13923.6 KII93386.1 - 3.9e-08 33.0 7.6 6.2e-08 32.4 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII93386.1 - 2e-06 27.6 10.0 3e-06 27.0 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII93386.1 - 1.9e-05 24.4 7.0 2.8e-05 23.9 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII93386.1 - 2e-05 24.8 10.6 3.1e-05 24.2 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII93386.1 - 0.00055 19.9 11.0 0.00098 19.1 11.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KII93386.1 - 0.021 14.6 5.4 0.021 14.6 5.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KII93386.1 - 0.024 14.7 4.9 0.052 13.6 4.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KII93386.1 - 0.033 14.3 10.8 0.066 13.4 10.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KII93386.1 - 0.4 10.7 11.2 2.4 8.2 11.9 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 KII93386.1 - 0.53 10.2 2.3 0.82 9.6 2.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 KII93386.1 - 2.1 8.7 10.3 18 5.7 10.6 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain ATP-synt_F PF01990.17 KII93387.1 - 1.4e-32 111.8 0.1 1.7e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 KII93387.1 - 0.059 13.2 0.1 0.07 13.0 0.1 1.1 1 0 0 1 1 1 0 PIN like domain DXP_synthase_N PF13292.6 KII93387.1 - 0.082 12.1 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2759 PF10958.8 KII93387.1 - 0.091 12.5 0.0 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) TIM21 PF08294.11 KII93388.1 - 1.8e-23 83.0 0.0 7.7e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 TIM21 DUF4218 PF13960.6 KII93390.1 - 1e-05 25.1 0.0 1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 KII93391.1 - 0.00043 19.6 0.1 0.0021 17.3 0.0 2.0 2 1 0 2 2 2 1 Transposase family tnp2 Transposase_21 PF02992.14 KII93392.1 - 0.0035 16.6 0.3 0.007 15.6 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 LSR PF05624.14 KII93392.1 - 8.9 6.4 13.5 15 5.7 13.5 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) PROCN PF08083.11 KII93393.1 - 0.13 10.9 0.1 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 PROCN (NUC071) domain PRIMA1 PF16101.5 KII93394.1 - 0.035 14.2 1.9 0.071 13.1 1.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Translin PF01997.16 KII93395.1 - 2.5e-67 226.8 0.0 2.9e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Translin family DUF3875 PF12991.7 KII93396.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) DcpS_C PF11969.8 KII93396.1 - 0.0018 18.8 0.9 0.0055 17.2 0.9 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding BLM10_mid PF16507.5 KII93397.1 - 9.7e-188 625.1 0.0 1.4e-187 624.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KII93397.1 - 1.9e-12 46.9 0.0 2.6e-11 43.3 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KII93397.1 - 4e-08 32.8 3.9 0.22 11.8 0.1 7.8 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KII93397.1 - 0.00031 21.1 4.8 0.1 13.0 0.0 5.5 6 0 0 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KII93397.1 - 0.0091 16.0 0.2 0.19 11.8 0.1 3.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KII93397.1 - 0.089 13.4 0.1 56 4.4 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region BATS PF06968.13 KII93400.1 - 8.5e-21 73.9 0.1 2.4e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KII93400.1 - 1.2e-15 58.3 0.0 2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily zf-H2C2_5 PF13909.6 KII93401.1 - 0.097 12.4 0.1 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain BTG PF07742.12 KII93406.1 - 6.4e-16 58.2 0.0 1.7e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 BTG family AAA_19 PF13245.6 KII93406.1 - 0.024 14.9 1.7 0.18 12.1 0.5 2.3 2 0 0 2 2 2 0 AAA domain Mcm10 PF09332.11 KII93406.1 - 0.28 10.5 5.0 0.43 9.9 5.0 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Ribosomal_S27e PF01667.17 KII93407.1 - 9.7e-30 102.1 3.9 1.2e-29 101.8 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 KII93407.1 - 0.033 14.6 1.2 0.24 11.8 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) TF_Zn_Ribbon PF08271.12 KII93407.1 - 0.1 12.1 2.0 0.15 11.6 2.0 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding 4HBT_3 PF13622.6 KII93408.1 - 1.7e-56 192.2 0.2 3.6e-56 191.2 0.0 1.7 2 0 0 2 2 2 1 Thioesterase-like superfamily XPA_C PF05181.12 KII93408.1 - 6e-24 83.8 1.5 1.1e-23 83.0 1.5 1.4 1 0 0 1 1 1 1 XPA protein C-terminus Acyl_CoA_thio PF02551.15 KII93408.1 - 7.3e-24 84.1 0.0 1.8e-18 66.7 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase XPA_N PF01286.18 KII93408.1 - 1.3e-05 25.1 4.2 3.6e-05 23.7 4.2 1.8 1 0 0 1 1 1 1 XPA protein N-terminal ZZ PF00569.17 KII93409.1 - 1e-25 89.2 40.4 1.1e-09 38.0 6.6 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 KII93409.1 - 1.8e-18 67.2 0.1 4.6e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 KII93409.1 - 1.4e-06 28.5 34.5 0.0078 16.5 6.0 3.5 3 0 0 3 3 3 3 C1 domain Chromo PF00385.24 KII93411.1 - 0.00087 19.2 0.9 0.0015 18.4 0.9 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ZZ PF00569.17 KII93412.1 - 3.1e-28 97.3 47.8 3.3e-10 39.6 10.2 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KII93412.1 - 0.00016 21.9 42.8 0.085 13.2 4.8 4.4 4 0 0 4 4 4 3 C1 domain Aminotran_4 PF01063.19 KII93413.1 - 6.1e-27 94.9 0.0 1.2e-26 94.0 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV ZZ PF00569.17 KII93414.1 - 2.6e-08 33.6 25.3 3e-07 30.2 6.0 2.7 3 0 0 3 3 3 2 Zinc finger, ZZ type C1_2 PF03107.16 KII93414.1 - 0.00027 21.2 24.0 0.008 16.5 6.0 3.1 3 0 0 3 3 3 2 C1 domain Eapp_C PF10238.9 KII93414.1 - 0.36 10.9 3.1 0.17 12.0 0.4 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein F-box-like PF12937.7 KII93415.1 - 7.7e-06 25.7 0.2 2e-05 24.4 0.2 1.7 1 1 0 1 1 1 1 F-box-like EF-hand_12 PF17901.1 KII93415.1 - 0.017 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand fold domain WD40 PF00400.32 KII93417.1 - 1e-57 190.7 22.9 3.1e-06 27.8 0.1 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 KII93417.1 - 2.2e-48 163.8 0.0 3.3e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.8 KII93417.1 - 0.00097 17.9 0.6 0.98 8.0 0.0 4.0 3 1 0 4 4 4 1 Nucleoporin Nup120/160 VID27 PF08553.10 KII93417.1 - 0.0022 17.1 0.0 0.5 9.4 0.0 3.0 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain Cytochrom_D1 PF02239.16 KII93417.1 - 0.0026 16.4 0.1 0.23 9.9 0.0 2.6 3 0 0 3 3 3 1 Cytochrome D1 heme domain Mcl1_mid PF12341.8 KII93417.1 - 0.028 13.8 0.2 0.45 9.8 0.1 2.9 4 0 0 4 4 4 0 Minichromosome loss protein, Mcl1, middle region FB_lectin PF07367.11 KII93417.1 - 0.15 12.0 0.2 0.49 10.3 0.1 1.8 2 0 0 2 2 2 0 Fungal fruit body lectin Forkhead PF00250.18 KII93419.1 - 2.2e-21 75.9 0.0 2.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Forkhead domain CBS PF00571.28 KII93420.1 - 1.9e-30 105.1 10.2 2.9e-08 34.0 0.0 5.5 6 0 0 6 6 6 4 CBS domain PB1 PF00564.24 KII93420.1 - 4e-09 36.3 0.0 9.1e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TGT PF01702.18 KII93421.1 - 0.23 10.6 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase UPF0121 PF03661.13 KII93422.1 - 7.1e-42 143.4 3.7 8e-42 143.3 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DEAD PF00270.29 KII93423.1 - 3.2e-46 157.3 0.0 5.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII93423.1 - 1.9e-24 86.2 0.0 1.9e-23 82.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KII93423.1 - 2.6e-18 66.0 0.5 5e-18 65.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KII93423.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 KII93423.1 - 0.019 14.9 0.5 0.035 14.1 0.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_22 PF13401.6 KII93423.1 - 0.2 11.9 0.2 0.81 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PTH2 PF01981.16 KII93424.1 - 9.4e-46 154.9 0.3 1.2e-45 154.5 0.3 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PhzC-PhzF PF02567.16 KII93424.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Chromo PF00385.24 KII93426.1 - 1.8e-07 31.0 0.1 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kinesin PF00225.23 KII93427.1 - 1.1e-56 192.1 0.0 1.6e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII93427.1 - 2.9e-09 37.0 0.0 5.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 KII93427.1 - 0.023 15.1 0.0 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KII93427.1 - 0.11 12.8 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KII93427.1 - 0.11 12.5 0.3 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain GST_N_3 PF13417.6 KII93428.1 - 1.5e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII93428.1 - 4.5e-05 23.7 0.0 8.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII93428.1 - 0.00042 20.6 0.0 0.00078 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII93428.1 - 0.014 15.4 0.4 0.03 14.4 0.4 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Colicin_im PF03857.13 KII93428.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein CopD PF05425.13 KII93429.1 - 0.015 15.7 0.3 0.032 14.6 0.3 1.5 1 0 0 1 1 1 0 Copper resistance protein D Pkinase_fungal PF17667.1 KII93430.1 - 1.4e-59 202.0 0.0 2.8e-59 200.9 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KII93430.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93430.1 - 0.089 12.1 0.0 0.65 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain NOA36 PF06524.12 KII93430.1 - 3.6 6.8 4.3 5.6 6.2 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein DNase_NucA_NucB PF14040.6 KII93431.1 - 8.2e-10 39.1 2.9 8.4e-10 39.0 0.2 2.3 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB ANAPC4_WD40 PF12894.7 KII93432.1 - 1.4e-05 25.3 0.0 0.19 12.0 0.0 5.2 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII93432.1 - 0.0001 23.0 30.7 2 9.4 0.1 9.7 10 0 0 10 10 10 3 WD domain, G-beta repeat BAT PF15915.5 KII93432.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 GAF and HTH_10 associated domain PD40 PF07676.12 KII93432.1 - 2 8.5 4.8 58 3.8 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-Tim10_DDP PF02953.15 KII93433.1 - 2.5e-21 75.1 1.9 2.8e-21 74.9 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger zf-met2 PF12907.7 KII93434.1 - 1.8e-14 53.6 4.0 2.6e-14 53.0 4.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KII93434.1 - 3.5e-05 24.6 13.3 3.5e-05 24.6 13.3 1.7 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_12 PF18658.1 KII93434.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type Beta_elim_lyase PF01212.21 KII93435.1 - 4e-69 233.1 0.0 5.1e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KII93435.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII93435.1 - 0.0018 16.9 0.0 0.0032 16.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KII93435.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Urb2 PF10441.9 KII93436.1 - 1e-40 139.9 0.1 1e-40 139.9 0.1 2.8 3 0 0 3 3 3 1 Urb2/Npa2 family IBR PF01485.21 KII93437.1 - 8.8e-15 54.7 41.2 4.1e-11 42.9 3.7 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KII93437.1 - 2.7e-13 50.2 0.0 4.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KII93437.1 - 4.9e-05 23.6 6.2 4.9e-05 23.6 6.2 4.1 4 0 0 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 KII93437.1 - 9.4e-05 22.1 2.3 9.4e-05 22.1 2.3 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KII93437.1 - 0.00014 21.8 5.9 0.00014 21.8 5.9 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII93437.1 - 0.0011 18.8 4.6 0.0011 18.8 4.6 4.6 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII93437.1 - 0.0031 17.4 6.5 0.0031 17.4 6.5 4.2 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII93437.1 - 0.0073 16.1 7.8 0.0073 16.1 7.8 5.2 4 1 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) KH_1 PF00013.29 KII93438.1 - 2.8e-39 132.8 0.5 1.1e-09 38.0 0.0 7.3 7 0 0 7 7 7 6 KH domain V-ATPase_C PF03223.15 KII93439.1 - 9.9e-132 439.8 3.0 1.1e-131 439.6 3.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Rhodanese PF00581.20 KII93440.1 - 1e-16 61.4 0.0 5.2e-10 39.8 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain Carm_PH PF17888.1 KII93443.1 - 0.019 15.3 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 Carmil pleckstrin homology domain DUF515 PF04415.12 KII93444.1 - 0.9 7.9 6.5 1.1 7.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Ctr PF04145.15 KII93445.1 - 3.6e-30 105.5 0.0 4.3e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Rhodanese PF00581.20 KII93446.1 - 5.4e-14 52.6 0.0 4.9e-13 49.5 0.0 2.0 1 1 1 2 2 2 1 Rhodanese-like domain Multi_ubiq PF14452.6 KII93446.1 - 0.078 13.2 0.1 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 Multiubiquitin Frataxin_Cyay PF01491.16 KII93447.1 - 8.4e-38 128.8 0.0 1.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Pox_Ag35 PF03286.14 KII93448.1 - 0.099 12.4 0.7 0.16 11.8 0.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4589 PF15252.6 KII93448.1 - 0.59 10.1 8.4 2.4 8.1 8.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) WD40 PF00400.32 KII93449.1 - 1.7e-17 63.5 9.5 0.00033 21.4 0.3 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KII93449.1 - 0.00039 19.5 0.1 0.0042 16.1 0.0 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KII93449.1 - 0.00052 20.3 0.0 12 6.2 0.0 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KII93449.1 - 0.0034 16.0 0.0 0.0067 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Bromodomain PF00439.25 KII93450.1 - 5.9e-40 135.2 0.0 8.2e-20 70.7 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KII93450.1 - 2.3e-15 56.5 0.2 4e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Bromodomain extra-terminal - transcription regulation zf-C2H2_assoc2 PF16624.5 KII93450.1 - 1.6 9.8 10.8 0.11 13.5 4.0 2.7 2 0 0 2 2 2 0 Unstructured region upstream of a zinc-finger Cupin_7 PF12973.7 KII93451.1 - 0.00018 21.3 0.1 0.00034 20.5 0.1 1.5 1 1 0 1 1 1 1 ChrR Cupin-like domain DMSP_lyase PF16867.5 KII93451.1 - 0.045 13.4 0.7 0.062 13.0 0.7 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase G-patch PF01585.23 KII93452.1 - 2.5e-10 40.1 0.1 5.6e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KII93452.1 - 3.6e-06 27.1 5.4 6.1e-06 26.4 5.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 KII93452.1 - 7.4e-05 22.8 0.1 7.4e-05 22.8 0.1 2.6 3 0 0 3 3 3 1 G-patch domain zf-met PF12874.7 KII93452.1 - 7.9e-05 22.9 1.6 0.00013 22.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KII93452.1 - 0.0016 18.7 0.6 0.0027 18.0 0.6 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) SAE2 PF08573.10 KII93452.1 - 0.0036 18.4 3.5 7.2 7.8 6.8 2.6 1 1 1 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C2H2_aberr PF17017.5 KII93452.1 - 0.016 15.4 0.6 0.024 14.8 0.6 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger Gemini_V2 PF01524.17 KII93452.1 - 0.16 12.2 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Geminivirus V2 protein DUF4820 PF16091.5 KII93452.1 - 0.64 9.3 12.4 0.077 12.3 8.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Helicase_C PF00271.31 KII93453.1 - 4.2e-19 68.9 0.1 9.7e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII93453.1 - 1.7e-18 67.2 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KII93453.1 - 2.4e-16 60.0 0.0 8.7e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KII93453.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PWI PF01480.17 KII93454.1 - 3.2e-09 37.0 0.0 5.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KII93454.1 - 1.9e-06 27.6 5.8 3.1e-06 26.9 5.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KII93454.1 - 0.0051 16.6 0.1 0.034 14.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KII93454.1 - 0.0058 16.6 9.0 0.0099 15.9 9.0 1.4 1 0 0 1 1 1 1 Zinc finger domain RRM_3 PF08777.11 KII93454.1 - 0.008 16.2 0.1 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif PRKG1_interact PF15898.5 KII93454.1 - 0.015 16.2 1.7 0.029 15.3 1.7 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 KII93454.1 - 0.083 12.4 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAP1 PF08601.10 KII93454.1 - 0.12 12.1 3.1 0.22 11.2 3.1 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4407 PF14362.6 KII93454.1 - 0.4 10.0 3.1 0.6 9.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCCH_2 PF14608.6 KII93454.1 - 2.6 8.6 3.9 4.2 8.0 3.9 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SAP130_C PF16014.5 KII93454.1 - 8.1 5.4 10.4 15 4.6 10.4 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MAP65_ASE1 PF03999.12 KII93454.1 - 9.7 4.7 8.2 18 3.8 8.2 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Aminotran_4 PF01063.19 KII93455.1 - 1.1e-29 103.9 0.0 1.7e-29 103.3 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV Trypsin_2 PF13365.6 KII93456.1 - 7.7e-07 30.1 0.1 1.5e-06 29.1 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Adeno_E3_CR2 PF02439.15 KII93457.1 - 0.021 14.5 3.3 0.038 13.7 3.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KII93457.1 - 0.032 14.5 2.2 0.27 11.5 0.0 3.1 2 0 0 2 2 2 0 Glycophorin A DUF3180 PF11377.8 KII93457.1 - 0.043 14.0 0.5 0.093 12.9 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) CD34_antigen PF06365.12 KII93457.1 - 0.063 12.9 0.4 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 KII93457.1 - 0.13 13.2 0.5 0.35 11.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PXA PF02194.15 KII93458.1 - 5.8e-46 156.8 0.5 1.3e-45 155.7 0.5 1.6 1 0 0 1 1 1 1 PXA domain Glucosamine_iso PF01182.20 KII93459.1 - 1.7e-70 237.4 0.0 1.9e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase aGPT-Pplase1 PF18723.1 KII93460.1 - 2e-100 335.9 0.0 3.8e-100 334.9 0.0 1.4 1 1 1 2 2 2 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KII93460.1 - 8.6e-12 44.8 0.5 3.6e-11 42.8 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.22 KII93461.1 - 6e-58 195.0 0.3 7e-58 194.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII93461.1 - 1.1e-32 112.8 0.0 1.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII93461.1 - 4.6e-14 52.3 0.1 5.9e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII93461.1 - 9.2e-08 32.2 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII93461.1 - 3.2e-07 29.9 0.1 4e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII93461.1 - 2.9e-06 26.9 0.1 7.7e-05 22.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII93461.1 - 5e-05 23.3 0.3 0.0044 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 KII93461.1 - 0.00036 20.4 0.5 0.014 15.2 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KII93461.1 - 0.00061 19.5 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KII93461.1 - 0.001 18.4 0.5 0.04 13.2 0.0 2.3 2 1 0 2 2 2 1 Septin cobW PF02492.19 KII93461.1 - 0.0013 18.4 0.0 0.0044 16.6 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 KII93461.1 - 0.0034 16.8 0.0 0.006 16.0 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KII93461.1 - 0.0078 16.5 0.1 0.02 15.2 0.0 1.8 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 KII93461.1 - 0.012 16.1 0.0 0.019 15.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KII93461.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII93461.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KII93461.1 - 0.021 15.4 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KII93461.1 - 0.044 13.7 0.7 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 KII93461.1 - 0.05 13.6 0.0 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_hydro_75 PF07335.11 KII93461.1 - 0.063 13.6 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NTPase_1 PF03266.15 KII93461.1 - 0.066 13.1 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 KII93461.1 - 0.074 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KII93461.1 - 0.12 12.9 0.1 0.49 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ATG16 PF08614.11 KII93462.1 - 1.8e-50 172.0 21.2 2.5e-50 171.5 21.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KII93462.1 - 0.00087 19.5 22.5 0.016 15.4 9.7 2.8 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding PilW PF16074.5 KII93462.1 - 0.02 14.9 1.0 0.041 13.9 0.6 1.7 1 1 0 1 1 1 0 Type IV Pilus-assembly protein W MPS2 PF17060.5 KII93462.1 - 0.19 11.0 8.1 0.27 10.5 8.1 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 YabA PF06156.13 KII93462.1 - 0.32 11.6 15.5 0.096 13.3 5.0 3.0 1 1 1 3 3 3 0 Initiation control protein YabA DUF4407 PF14362.6 KII93462.1 - 0.43 9.9 13.1 0.28 10.5 11.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KII93462.1 - 0.83 8.7 13.7 1.4 7.9 13.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 KII93462.1 - 3.5 8.1 10.6 1.7 9.2 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KII93462.1 - 7.6 6.6 8.3 20 5.2 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C2H2 PF00096.26 KII93464.1 - 4.3e-07 30.0 20.7 6.6e-06 26.3 1.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII93464.1 - 1.2e-06 28.8 14.6 0.00054 20.6 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII93464.1 - 0.0038 17.6 14.9 0.15 12.6 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KII93464.1 - 0.0049 17.1 4.8 0.014 15.6 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 KII93464.1 - 0.009 16.1 1.4 1.3 9.2 0.2 2.4 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KII93464.1 - 0.017 15.1 0.2 0.017 15.1 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 KII93464.1 - 0.11 12.9 0.2 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KII93464.1 - 2.4 8.0 8.3 14 5.5 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KII93464.1 - 7.8 6.4 12.7 1.6 8.6 4.2 3.1 3 1 0 3 3 3 0 C2H2-type zinc-finger domain ABC_membrane PF00664.23 KII93465.1 - 9.3e-52 176.3 24.6 6.1e-26 91.7 7.6 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII93465.1 - 1.3e-43 148.8 0.0 8.9e-26 91.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII93465.1 - 2.4e-10 40.2 2.1 0.043 13.2 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII93465.1 - 3.4e-06 27.6 0.4 0.036 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KII93465.1 - 4.5e-06 26.3 0.6 0.012 15.3 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KII93465.1 - 1e-05 26.1 0.5 0.00046 20.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KII93465.1 - 1.1e-05 24.7 0.0 0.00048 19.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KII93465.1 - 7.8e-05 22.3 0.0 0.48 10.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KII93465.1 - 0.0011 19.3 0.2 0.71 10.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KII93465.1 - 0.0012 18.8 4.1 0.33 10.7 0.1 4.0 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 KII93465.1 - 0.0024 17.4 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KII93465.1 - 0.0034 17.5 1.5 0.13 12.3 0.2 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII93465.1 - 0.0044 16.4 0.3 0.56 9.5 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.6 KII93465.1 - 0.0054 17.3 0.0 1.8 9.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 KII93465.1 - 0.0086 16.2 0.4 0.84 9.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII93465.1 - 0.022 14.7 0.2 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 KII93465.1 - 0.024 14.4 0.1 0.47 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 KII93465.1 - 0.049 12.4 0.5 0.26 10.0 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 KII93465.1 - 0.064 13.0 0.0 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KII93465.1 - 0.065 12.7 0.8 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.14 KII93465.1 - 0.085 12.9 0.4 19 5.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KII93465.1 - 0.091 12.5 0.0 9.7 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 KII93465.1 - 0.099 12.4 0.2 25 4.6 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 KII93465.1 - 0.13 12.2 0.1 1 9.2 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 KII93465.1 - 0.14 12.2 0.4 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 KII93465.1 - 0.15 11.6 3.2 0.31 10.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KII93465.1 - 0.17 11.9 0.0 2.7 8.0 0.1 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 KII93465.1 - 0.18 11.6 0.4 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KII93465.1 - 0.2 11.5 2.5 2.8 7.8 0.1 3.0 3 0 0 3 3 3 0 NTPase TrwB_AAD_bind PF10412.9 KII93465.1 - 0.22 10.4 1.2 4.7 6.0 0.5 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 KII93465.1 - 0.39 9.5 2.1 6.1 5.5 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ABC_membrane PF00664.23 KII93466.1 - 2e-55 188.4 27.0 1e-30 107.4 8.1 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KII93466.1 - 3.5e-43 147.4 0.0 1.6e-26 93.4 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII93466.1 - 1.4e-11 44.3 1.8 0.017 14.5 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII93466.1 - 1.3e-06 28.9 0.3 0.027 14.9 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KII93466.1 - 2.2e-06 27.3 0.4 0.0071 16.1 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KII93466.1 - 4.4e-06 25.9 0.1 0.00037 19.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KII93466.1 - 1.2e-05 25.0 0.4 0.15 11.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KII93466.1 - 0.00011 22.8 4.5 0.00066 20.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KII93466.1 - 0.00062 20.1 0.1 0.55 10.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII93466.1 - 0.0019 17.7 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 KII93466.1 - 0.002 18.0 4.3 0.43 10.3 0.1 4.0 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KII93466.1 - 0.0042 17.6 0.3 2.4 8.7 0.0 3.9 5 0 0 5 5 3 1 AAA domain FtsK_SpoIIIE PF01580.18 KII93466.1 - 0.0044 16.4 1.1 0.5 9.7 0.0 2.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.17 KII93466.1 - 0.0051 16.9 2.2 0.15 12.1 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 KII93466.1 - 0.006 16.7 0.4 0.82 9.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII93466.1 - 0.0073 16.2 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Adeno_IVa2 PF02456.15 KII93466.1 - 0.024 13.4 0.2 0.28 9.9 0.0 2.5 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_30 PF13604.6 KII93466.1 - 0.039 13.7 0.5 0.56 9.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KII93466.1 - 0.04 13.7 0.3 12 5.6 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 KII93466.1 - 0.047 13.7 0.1 2 8.4 0.2 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.12 KII93466.1 - 0.065 12.7 0.9 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein IstB_IS21 PF01695.17 KII93466.1 - 0.07 12.9 0.0 11 5.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KII93466.1 - 0.094 12.7 0.3 20 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KII93466.1 - 0.094 12.4 0.1 11 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KII93466.1 - 0.11 12.4 1.8 2.8 7.8 0.1 2.9 3 0 0 3 3 3 0 NTPase ATPase_2 PF01637.18 KII93466.1 - 0.14 12.1 0.0 1.8 8.4 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KII93466.1 - 0.17 11.7 0.4 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 KII93466.1 - 0.18 11.5 0.0 0.59 9.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KII93466.1 - 0.21 11.2 3.8 0.31 10.6 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KII93466.1 - 0.26 10.1 1.9 7.3 5.3 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TrwB_AAD_bind PF10412.9 KII93466.1 - 0.34 9.8 1.8 4.1 6.2 0.3 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KII93466.1 - 0.42 10.5 1.4 6.8 6.6 0.2 2.7 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KII93466.1 - 0.45 10.5 1.9 39 4.3 0.3 2.9 3 0 0 3 3 3 0 Dynamin family RhoGAP PF00620.27 KII93467.1 - 1.7e-42 144.8 0.2 1.4e-41 141.8 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KII93467.1 - 3.5e-08 33.6 1.0 1.6e-07 31.5 1.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5137 PF17220.3 KII93467.1 - 0.39 11.6 2.4 2.6 9.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5137) PIF1 PF05970.14 KII93468.1 - 4.3e-09 36.0 0.0 5.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 KII93468.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 KII93468.1 - 0.014 15.3 0.0 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain EHN PF06441.12 KII93470.1 - 8.1e-31 106.6 0.1 1.5e-30 105.7 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KII93470.1 - 1.9e-08 34.3 0.1 4.7e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold FAD_binding_6 PF00970.24 KII93471.1 - 2.2e-34 117.7 0.0 3.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KII93471.1 - 4.9e-31 107.6 0.0 8.2e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KII93471.1 - 0.00016 21.9 0.0 0.0064 16.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KII93471.1 - 0.011 16.0 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DSPc PF00782.20 KII93473.1 - 7.7e-22 77.5 0.0 1.3e-19 70.3 0.0 3.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII93473.1 - 0.0041 16.7 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KII93473.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 KII93473.1 - 0.21 11.9 0.0 0.44 10.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF846 PF05832.12 KII93474.1 - 8.2e-53 178.2 9.0 1e-52 177.9 9.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Myelin_PLP PF01275.19 KII93474.1 - 0.026 14.4 3.6 0.24 11.3 4.0 1.9 1 1 1 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) DUF2207 PF09972.9 KII93474.1 - 1.5 7.5 5.9 3.8 6.2 1.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3792 PF12670.7 KII93474.1 - 6 7.1 12.7 0.075 13.2 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) ATG16 PF08614.11 KII93476.1 - 0.011 15.9 4.9 0.011 15.9 4.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-B_N PF04218.13 KII93476.1 - 0.15 11.7 0.4 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain RNA_pol_Rpb8 PF03870.15 KII93478.1 - 7.7e-47 159.0 0.0 9.1e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.20 KII93480.1 - 3.6e-23 82.2 0.0 5.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KII93480.1 - 4.4e-12 46.4 0.0 7.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KII93480.1 - 8.4e-08 32.7 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PH domain ABC_trans_N PF14510.6 KII93480.1 - 0.023 15.3 0.6 0.093 13.4 0.0 2.4 2 0 0 2 2 2 0 ABC-transporter N-terminal Pescadillo_N PF06732.11 KII93481.1 - 1.1e-121 405.6 1.0 2.4e-121 404.5 0.0 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KII93481.1 - 1.2e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KII93481.1 - 1.6e-06 28.4 0.0 3.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KII93481.1 - 0.005 17.1 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain LSM PF01423.22 KII93482.1 - 9.6e-18 63.6 0.1 1.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KII93482.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Hfq protein DUF3752 PF12572.8 KII93482.1 - 0.1 13.1 0.4 0.15 12.6 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) RdRP PF05183.12 KII93483.1 - 2.2e-174 581.4 0.0 3.6e-174 580.7 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Complex1_LYR PF05347.15 KII93484.1 - 2e-16 59.8 0.7 2.4e-16 59.5 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KII93484.1 - 0.011 16.3 0.1 0.014 15.9 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Cyclin_N PF00134.23 KII93487.1 - 6e-38 129.5 1.2 1.4e-37 128.2 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KII93487.1 - 7.3e-08 32.5 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4838 PF16126.5 KII93487.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) DUF4364 PF14277.6 KII93487.1 - 0.092 12.5 0.2 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) GFO_IDH_MocA PF01408.22 KII93488.1 - 9e-11 42.6 0.2 7.3e-10 39.7 0.2 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII93488.1 - 0.019 15.0 0.0 0.061 13.3 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Lyase_8 PF02278.18 KII93490.1 - 2.2e-68 230.5 0.9 3.7e-68 229.8 0.9 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KII93490.1 - 7.4e-19 67.8 0.3 1.1e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KII93490.1 - 2.6e-11 43.8 2.0 4.9e-11 43.0 0.9 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain CAP PF00188.26 KII93492.1 - 3.1e-22 79.7 0.9 3.1e-22 79.7 0.9 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 KII93493.1 - 2.1e-25 90.0 0.9 2.6e-25 89.7 0.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2012 PF09430.10 KII93494.1 - 3.5e-23 82.0 0.0 5.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 KII93494.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Fcf1 PF04900.12 KII93495.1 - 2.2e-34 117.8 0.5 3.6e-34 117.1 0.5 1.4 1 0 0 1 1 1 1 Fcf1 WAC_Acf1_DNA_bd PF10537.9 KII93497.1 - 8.1e-34 116.2 1.4 8.1e-34 116.2 1.4 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KII93497.1 - 2.2e-32 111.5 0.1 2.2e-32 111.5 0.1 3.4 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KII93497.1 - 1.2e-13 51.2 0.1 2.5e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KII93497.1 - 3e-05 23.4 0.0 6.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDHD PF02862.17 KII93497.1 - 0.49 10.5 4.9 6 7.0 0.1 2.4 2 0 0 2 2 2 0 DDHD domain YL1 PF05764.13 KII93497.1 - 2.2 8.3 30.1 2.4 8.2 13.4 2.7 2 0 0 2 2 2 0 YL1 nuclear protein CDK2AP PF09806.9 KII93497.1 - 7.1 6.6 12.9 0.16 12.0 5.8 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Nop53 PF07767.11 KII93497.1 - 7.3 5.9 39.6 0.94 8.8 15.4 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Aa_trans PF01490.18 KII93498.1 - 9e-56 189.3 16.4 1e-55 189.2 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KII93498.1 - 0.00011 21.4 9.8 0.00011 21.4 9.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CSN8_PSD8_EIF3K PF10075.9 KII93499.1 - 2.7e-22 79.3 0.0 4.6e-22 78.5 0.0 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 KII93500.1 - 2.3e-64 211.8 17.5 3.7e-10 40.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII93500.1 - 4.1e-29 100.7 0.8 1.7e-06 28.2 0.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII93500.1 - 3.5e-12 46.6 0.1 0.00011 22.2 0.0 3.7 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KII93500.1 - 2.6e-10 39.8 3.1 0.0022 17.0 0.0 4.0 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KII93500.1 - 4.2e-10 38.9 6.0 0.0022 16.7 0.2 5.2 2 1 4 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KII93500.1 - 7.5e-08 32.0 0.0 0.00068 19.0 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 KII93500.1 - 0.00012 20.7 0.5 1.5 7.2 0.1 3.4 1 1 3 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KII93500.1 - 0.00032 19.9 0.2 0.11 11.5 0.0 3.0 1 1 2 3 3 3 1 Coatomer WD associated region Nbas_N PF15492.6 KII93500.1 - 0.0045 16.4 0.6 7.4 5.8 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KII93500.1 - 0.0098 15.0 0.2 1.8 7.6 0.0 3.0 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) IKI3 PF04762.12 KII93500.1 - 0.012 13.7 0.1 0.044 11.8 0.0 1.9 2 0 0 2 2 2 0 IKI3 family PD40 PF07676.12 KII93500.1 - 0.036 14.0 0.6 14 5.8 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 KII93500.1 - 0.036 13.0 0.7 4.2 6.2 0.0 3.5 1 1 3 4 4 4 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KII93500.1 - 0.08 12.2 0.0 1.6 7.9 0.0 2.7 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus rOmpB PF12334.8 KII93500.1 - 0.13 11.7 0.0 0.39 10.2 0.0 1.7 1 1 0 2 2 2 0 Rickettsia outer membrane protein B ubiquitin PF00240.23 KII93501.1 - 1.1e-136 444.8 18.7 1.6e-33 114.3 0.5 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KII93501.1 - 6.6e-63 208.5 20.7 3.7e-15 55.5 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KII93501.1 - 7.6e-23 80.8 9.1 0.0005 20.5 0.1 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KII93501.1 - 8.2e-16 57.7 3.1 0.041 13.8 0.0 4.3 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KII93501.1 - 2e-14 53.7 7.1 0.045 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KII93501.1 - 3e-14 53.0 2.6 0.13 12.4 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KII93501.1 - 8.3e-13 48.8 0.9 0.44 11.1 0.0 4.3 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KII93501.1 - 1.1e-09 38.4 0.4 1.4 8.7 0.0 4.2 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KII93501.1 - 9.2e-07 28.4 0.6 1.2 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 KII93501.1 - 1.6e-06 28.0 24.6 19 5.4 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain ACT_5 PF13710.6 KII93501.1 - 8.3e-06 25.6 3.4 9.6 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain UDP-g_GGTase PF06427.11 KII93501.1 - 8.4e-06 25.9 1.7 8.4 6.6 0.0 4.3 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 KII93501.1 - 1.2e-05 25.6 0.0 35 4.9 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KII93501.1 - 1.2e-05 25.4 3.4 16 5.8 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KII93501.1 - 1.8e-05 25.4 1.8 33 5.3 0.1 4.4 4 1 0 4 4 4 0 Bacterial Ig domain TmoB PF06234.12 KII93501.1 - 2.2e-05 24.4 0.0 35 4.6 0.0 4.7 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF969 PF06149.12 KII93501.1 - 0.00069 19.1 0.0 26 4.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KII93501.1 - 0.00084 19.9 1.3 77 4.0 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 KII93501.1 - 0.0054 17.3 0.1 1.6e+02 3.0 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KII93501.1 - 0.013 15.6 0.0 1.1e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KII93501.1 - 0.02 15.0 5.2 76 3.6 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KII93501.1 - 0.078 12.8 9.2 51 3.8 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 KII93501.1 - 0.18 12.3 8.1 1.2e+02 3.2 0.1 4.0 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain Tash_PEST PF07708.11 KII93501.1 - 0.25 11.5 27.2 7.2 6.9 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif YcgR_2 PF12945.7 KII93501.1 - 2 8.6 4.6 2.8e+02 1.7 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KII93501.1 - 2 8.2 8.5 1.1e+02 2.6 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KII93501.1 - 2.2 8.5 9.9 1.2e+02 2.9 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 KII93501.1 - 2.8 7.9 8.1 1.5e+02 2.4 0.1 4.7 4 0 0 4 4 4 0 Ribosomal family S4e Ribosomal_S3_C PF00189.20 KII93502.1 - 1.9e-25 89.2 0.1 7e-25 87.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KII93502.1 - 1.2e-11 44.3 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KII93502.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KII93502.1 - 0.23 11.3 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Mucin PF01456.17 KII93503.1 - 0.0014 18.6 37.4 0.0019 18.2 37.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein CDC27 PF09507.10 KII93503.1 - 0.12 11.7 4.1 0.14 11.6 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FSA_C PF10479.9 KII93503.1 - 1.1 7.3 16.5 1.4 7.0 16.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Shisa PF13908.6 KII93503.1 - 6.7 6.9 10.6 10 6.3 10.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 KII93503.1 - 9.8 6.1 13.7 14 5.6 13.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family Amidase PF01425.21 KII93504.1 - 3.3e-109 365.8 0.0 4.7e-109 365.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Thiolase_N PF00108.23 KII93505.1 - 2e-66 224.0 0.0 2.8e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KII93505.1 - 7.4e-40 135.4 0.0 2.5e-39 133.7 0.0 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KII93505.1 - 0.0023 17.6 0.3 0.0086 15.7 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KII93505.1 - 0.11 12.5 0.1 43 4.2 0.0 3.7 3 1 1 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain FAE1_CUT1_RppA PF08392.12 KII93505.1 - 0.13 11.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 KII93505.1 - 0.13 12.1 1.8 6.1 6.8 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L32p PF01783.23 KII93506.1 - 1.9e-16 60.1 5.9 2.6e-16 59.6 5.9 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 KII93506.1 - 0.00026 20.9 0.3 0.00036 20.4 0.3 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 KII93506.1 - 0.11 11.9 3.7 0.19 11.2 3.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain ETC_C1_NDUFA5 PF04716.14 KII93507.1 - 4.5e-26 90.4 0.1 8.4e-26 89.6 0.0 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region RPE65 PF03055.15 KII93508.1 - 2.2e-96 323.9 0.0 2.6e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GTP_EFTU PF00009.27 KII93509.1 - 3.1e-53 180.2 0.1 4.8e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KII93509.1 - 1.4e-42 144.6 0.0 2.9e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KII93509.1 - 9.9e-14 51.5 2.4 1.5e-13 50.9 0.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII93509.1 - 0.0013 18.8 0.1 0.03 14.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 KII93509.1 - 0.046 13.8 0.2 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain NIF3 PF01784.18 KII93509.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Pkinase PF00069.25 KII93510.1 - 3e-40 138.2 0.0 2.6e-38 131.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93510.1 - 2e-14 53.5 0.0 7e-13 48.4 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KII93510.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII93510.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII93510.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII93510.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LSM PF01423.22 KII93511.1 - 1.6e-18 66.1 0.1 2.3e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KII93511.1 - 0.0094 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Hfq protein PHD PF00628.29 KII93512.1 - 4.6e-10 39.2 7.6 4.6e-10 39.2 7.6 2.4 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.8 KII93512.1 - 0.0067 16.2 0.5 0.0067 16.2 0.5 2.0 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain REV1_C PF16727.5 KII93512.1 - 0.091 13.2 2.6 0.27 11.7 2.6 1.7 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain CENP-F_leu_zip PF10473.9 KII93512.1 - 0.97 9.5 6.9 0.17 11.9 2.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HABP4_PAI-RBP1 PF04774.15 KII93514.1 - 1.5e-11 45.2 6.8 6.1e-11 43.2 6.8 2.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.22 KII93515.1 - 9.5e-26 90.7 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.17 KII93516.1 - 7.1e-65 218.8 0.0 8.3e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.18 KII93517.1 - 4.4e-51 171.8 2.1 5.1e-51 171.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Acetyltransf_1 PF00583.25 KII93518.1 - 0.001 19.3 0.0 0.0019 18.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII93518.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII93518.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KII93518.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DLH PF01738.18 KII93519.1 - 2.6e-23 82.7 0.0 3.4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KII93519.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase MFS_1 PF07690.16 KII93520.1 - 1.6e-43 149.0 35.7 1.6e-43 149.0 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KII93520.1 - 3.8e-07 29.3 0.1 1.1e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 MFS_1 like family OATP PF03137.20 KII93520.1 - 0.015 13.6 4.0 0.12 10.7 0.0 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KII93520.1 - 0.054 11.9 4.9 0.085 11.2 4.9 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 KII93524.1 - 1.4e-33 116.3 33.0 1.4e-33 116.3 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Elong_Iki1 PF10483.9 KII93526.1 - 4.3e-10 39.6 0.0 8.5e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 SLX9 PF15341.6 KII93528.1 - 1e-22 80.9 3.4 1.5e-22 80.4 3.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF1168 PF06658.12 KII93528.1 - 0.11 12.3 3.5 0.21 11.4 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HAUS-augmin3 PF14932.6 KII93529.1 - 0.024 14.2 6.5 0.031 13.9 6.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HisKA_3 PF07730.13 KII93529.1 - 0.1 13.2 4.3 0.4 11.2 0.1 2.3 1 1 1 2 2 2 0 Histidine kinase DUF724 PF05266.14 KII93529.1 - 0.15 11.8 7.5 0.21 11.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cir_N PF10197.9 KII93529.1 - 0.21 11.8 2.0 0.68 10.2 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR CENP-H PF05837.12 KII93529.1 - 0.31 11.5 10.3 0.23 11.9 8.4 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KII93529.1 - 5.4 7.5 13.9 32 5.0 13.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 KII93529.1 - 5.7 7.6 8.4 5.1 7.8 0.1 2.7 1 1 1 2 2 2 0 SlyX DUF4164 PF13747.6 KII93531.1 - 0.0085 16.3 3.2 0.0085 16.3 3.2 3.5 2 2 1 4 4 4 1 Domain of unknown function (DUF4164) DUF2540 PF10802.8 KII93531.1 - 0.049 13.7 0.5 0.14 12.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Eaf7 PF07904.13 KII93531.1 - 1.6 9.2 4.4 3.2 8.2 3.7 2.0 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 2-oxoacid_dh PF00198.23 KII93532.1 - 2.3e-79 266.1 0.0 3e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KII93532.1 - 2e-19 69.2 2.3 3.6e-19 68.4 0.8 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 KII93532.1 - 7.9e-15 54.9 0.3 2.6e-14 53.3 0.3 2.0 1 0 0 1 1 1 1 e3 binding domain PRCC PF10253.9 KII93532.1 - 0.049 14.4 0.1 0.091 13.5 0.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting QRPTase_N PF02749.16 KII93532.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain EXOSC1 PF10447.9 KII93533.1 - 1.2e-17 64.5 1.4 9.8e-13 48.7 0.3 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KII93533.1 - 2.3e-05 24.1 0.1 5.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region NUDE_C PF04880.13 KII93534.1 - 2.6e-12 47.6 6.0 2.6e-12 47.6 6.0 6.8 2 2 4 7 7 7 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KII93534.1 - 0.00061 20.7 8.9 0.00061 20.7 8.9 3.7 1 1 2 3 3 3 2 cGMP-dependent protein kinase interacting domain DUF2353 PF09789.9 KII93534.1 - 0.005 16.2 9.9 0.005 16.2 9.9 2.6 1 1 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) HIP1_clath_bdg PF16515.5 KII93534.1 - 0.29 11.8 26.5 4.5 7.9 2.9 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KII93534.1 - 0.42 11.1 29.1 0.054 13.9 2.0 3.7 3 1 1 4 4 4 0 Cell division protein ZapB Tup_N PF08581.10 KII93534.1 - 1.5 9.2 21.4 0.55 10.6 7.6 3.5 1 1 2 3 3 3 0 Tup N-terminal Spc7 PF08317.11 KII93534.1 - 1.5 7.6 27.8 0.25 10.2 12.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein NUDIX PF00293.28 KII93535.1 - 3.3e-09 36.9 0.2 4.4e-09 36.5 0.2 1.5 1 1 0 1 1 1 1 NUDIX domain Es2 PF09751.9 KII93536.1 - 6.3e-83 279.9 0.2 1.5e-82 278.7 0.2 1.6 1 1 0 1 1 1 1 Nuclear protein Es2 Nefa_Nip30_N PF10187.9 KII93537.1 - 2.1e-32 111.6 13.0 2.1e-32 111.6 13.0 2.1 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2791 PF10923.8 KII93537.1 - 0.1 11.4 0.9 0.15 10.9 0.9 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF572 PF04502.13 KII93537.1 - 1.7 8.2 15.7 2.1 7.9 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) EamA PF00892.20 KII93539.1 - 1.2e-11 44.9 30.4 9.2e-07 29.1 3.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 KII93539.1 - 0.017 14.6 10.2 0.38 10.2 0.5 3.6 3 1 1 4 4 4 0 Solute carrier family 35 DUF3955 PF13127.6 KII93539.1 - 0.028 14.2 1.4 0.028 14.2 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) TPT PF03151.16 KII93539.1 - 0.034 13.5 0.3 0.034 13.5 0.3 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF4131 PF13567.6 KII93539.1 - 0.29 10.8 6.7 1.3 8.7 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) HAUS-augmin3 PF14932.6 KII93540.1 - 0.054 13.1 21.2 0.74 9.3 9.0 3.0 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 KII93540.1 - 0.079 13.4 25.6 0.39 11.2 2.2 4.8 4 0 0 4 4 4 0 Cell division protein ZapB HAP1_N PF04849.13 KII93540.1 - 0.13 11.4 28.8 2.3 7.4 0.0 3.2 2 1 0 2 2 2 0 HAP1 N-terminal conserved region T3SS_TC PF06511.11 KII93540.1 - 0.44 9.9 16.2 0.11 11.8 6.6 3.5 4 0 0 4 4 4 0 Type III secretion systems tip complex components YabA PF06156.13 KII93540.1 - 3 8.5 20.5 1.7 9.3 0.4 4.6 3 1 0 3 3 3 0 Initiation control protein YabA Rad51 PF08423.11 KII93541.1 - 2.1e-12 46.9 0.0 3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KII93541.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KII93541.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC RecA PF00154.21 KII93541.1 - 0.058 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ATPase_2 PF01637.18 KII93541.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_35 PF14516.6 KII93541.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MIase PF02426.16 KII93541.1 - 0.13 12.5 0.0 27 5.0 0.0 2.5 2 0 0 2 2 2 0 Muconolactone delta-isomerase AAA_11 PF13086.6 KII93541.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KII93541.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AMP-binding PF00501.28 KII93542.1 - 1.6e-22 79.7 0.0 3.3e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KII93542.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter 53-BP1_Tudor PF09038.10 KII93542.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor PPR_2 PF13041.6 KII93544.1 - 3.6e-27 94.3 0.0 6.9e-06 26.2 0.0 5.9 6 0 0 6 6 6 5 PPR repeat family PPR_3 PF13812.6 KII93544.1 - 9.4e-19 67.3 0.0 0.0044 17.1 0.0 6.2 5 1 1 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 KII93544.1 - 1.6e-12 47.2 0.5 0.00083 18.8 0.0 4.3 4 0 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KII93544.1 - 2.4e-11 43.1 0.1 0.037 14.3 0.0 6.2 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 KII93544.1 - 9.1e-07 28.5 0.0 1.2 8.9 0.0 5.1 5 0 0 5 5 5 2 PPR repeat MRP-S27 PF10037.9 KII93544.1 - 0.1 11.5 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Hap4_Hap_bind PF10297.9 KII93545.1 - 4.7e-09 36.1 3.6 1.1e-08 34.9 3.6 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KII93545.1 - 4.5e-05 23.5 17.4 0.0004 20.4 13.0 2.4 1 1 1 2 2 2 2 bZIP transcription factor ZapB PF06005.12 KII93545.1 - 0.086 13.3 11.3 0.19 12.2 11.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 KII93545.1 - 0.1 12.7 16.7 2.1 8.5 4.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper YabA PF06156.13 KII93545.1 - 0.15 12.7 3.3 0.31 11.7 3.3 1.5 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 KII93545.1 - 0.22 11.8 2.6 0.39 11.0 2.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2205 PF10224.9 KII93545.1 - 0.51 10.4 4.5 1.5 8.8 4.5 1.9 1 1 0 1 1 1 0 Short coiled-coil protein eIF2A PF08662.11 KII93546.1 - 1.4e-40 139.3 2.2 2.6e-36 125.3 0.1 4.9 3 3 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KII93546.1 - 1.9e-07 30.8 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KII93546.1 - 0.0094 16.8 1.1 3.6 8.6 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat Sugar_tr PF00083.24 KII93547.1 - 2.9e-47 161.6 23.8 4.5e-46 157.6 23.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII93547.1 - 6.3e-17 61.5 36.3 4.6e-09 35.7 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KII93547.1 - 0.0086 14.7 22.5 0.033 12.8 5.7 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein SLS PF14611.6 KII93548.1 - 6e-11 42.6 0.0 1.5e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.12 KII93549.1 - 3.9e-79 265.2 24.6 3.9e-79 265.2 24.6 2.7 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KII93549.1 - 4.3e-55 186.6 0.0 1.6e-54 184.7 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KII93549.1 - 2.3e-45 154.3 6.4 2.3e-45 154.3 6.4 5.8 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Lar_N PF09861.9 KII93549.1 - 0.021 14.0 0.3 0.045 12.9 0.3 1.5 1 0 0 1 1 1 0 Lactate racemase N-terminal domain UPF0181 PF03701.14 KII93549.1 - 0.37 10.5 2.6 0.75 9.5 0.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) DUF423 PF04241.15 KII93550.1 - 1.1e-22 80.0 2.1 1.4e-22 79.7 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ras PF00071.22 KII93552.1 - 9.8e-54 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII93552.1 - 1.5e-21 76.9 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII93552.1 - 6.8e-06 25.6 0.0 9.7e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Requiem_N PF14051.6 KII93553.1 - 0.0089 16.2 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DPF2/REQ. DUF3357 PF11837.8 KII93553.1 - 0.048 14.1 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Zn_clus PF00172.18 KII93554.1 - 1.2e-07 31.7 10.2 2.6e-07 30.6 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII93554.1 - 4.5e-06 25.9 0.2 1.4e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain PDT PF00800.18 KII93555.1 - 2.5e-52 177.3 0.0 3.4e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KII93555.1 - 0.066 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF1522 PF07482.11 KII93555.1 - 0.2 12.0 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) zf-CCCH PF00642.24 KII93556.1 - 1.5e-20 72.6 24.5 2.5e-05 24.0 0.6 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII93556.1 - 2.5e-14 52.8 31.3 1e-06 28.6 2.1 4.8 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KII93556.1 - 2.1e-07 31.6 20.1 0.00043 20.9 0.2 4.4 1 1 4 5 5 5 4 Torus domain zf-CCCH_2 PF14608.6 KII93556.1 - 8.8e-06 26.0 28.0 0.0027 18.1 0.5 5.3 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-CCHC PF00098.23 KII93556.1 - 1.2e-05 25.2 3.7 4.8e-05 23.2 3.7 2.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_4 PF18044.1 KII93556.1 - 2.5e-05 24.0 0.4 2.5e-05 24.0 0.4 5.2 6 0 0 6 6 6 1 CCCH-type zinc finger zf-CCHC_3 PF13917.6 KII93556.1 - 0.019 14.9 0.1 0.058 13.4 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_3 PF15663.5 KII93556.1 - 1.2 9.4 15.1 2.8 8.2 0.5 3.6 1 1 2 3 3 3 0 Zinc-finger containing family UPF0047 PF01894.17 KII93557.1 - 2.9e-36 124.1 0.0 3.3e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KII93558.1 - 1e-07 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RhoGEF PF00621.20 KII93560.1 - 3.2e-17 63.3 0.0 5.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Exo_endo_phos PF03372.23 KII93561.1 - 9.5e-16 58.0 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.21 KII93562.1 - 9.8e-17 61.6 0.0 8.4e-10 39.0 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KII93562.1 - 5.8e-09 36.1 0.0 3.5e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KII93562.1 - 0.062 12.4 0.5 0.84 8.7 0.3 2.2 2 0 0 2 2 2 0 Peptidase M16C associated RQC PF09382.10 KII93562.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 RQC domain NUFIP1 PF10453.9 KII93564.1 - 5.7e-19 67.7 1.0 9.2e-19 67.0 1.0 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.12 KII93564.1 - 0.0083 16.2 0.3 0.016 15.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) KH_1 PF00013.29 KII93565.1 - 1.3e-40 137.0 11.3 3.5e-16 58.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KII93565.1 - 2.3e-11 43.4 0.8 0.0013 18.6 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 KII93565.1 - 1.1e-08 34.7 7.4 0.056 13.3 0.1 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 KII93565.1 - 2.4e-05 24.3 3.2 0.085 13.0 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain Ribosomal_L13 PF00572.18 KII93566.1 - 3.1e-11 43.6 0.0 1.2e-09 38.5 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 SGL PF08450.12 KII93567.1 - 9.2e-66 221.9 0.1 1.4e-65 221.3 0.0 1.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KII93567.1 - 0.0034 17.6 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 Arylesterase ANAPC4_WD40 PF12894.7 KII93567.1 - 0.19 12.0 0.0 12 6.3 0.0 3.1 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PP-binding PF00550.25 KII93568.1 - 3.4e-11 43.3 0.2 4.9e-11 42.8 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KII93568.1 - 1.3e-05 25.3 0.3 1.7e-05 25.0 0.3 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L17 PF01196.19 KII93569.1 - 1.8e-35 121.7 0.0 3.6e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 ADH_N PF08240.12 KII93570.1 - 6.1e-30 103.3 0.1 6.1e-30 103.3 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII93570.1 - 5.2e-11 42.6 0.2 2.9e-08 33.8 0.0 2.3 1 1 0 2 2 2 2 Zinc-binding dehydrogenase QRPTase_C PF01729.19 KII93570.1 - 0.0023 17.8 0.0 0.0067 16.2 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 KII93570.1 - 0.0028 17.0 0.1 0.0052 16.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 KII93570.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Tetraspanin PF00335.20 KII93572.1 - 0.048 13.4 7.9 0.076 12.7 7.9 1.4 1 1 0 1 1 1 0 Tetraspanin family E1_DerP2_DerF2 PF02221.15 KII93573.1 - 3.5e-25 89.0 0.6 4.3e-25 88.7 0.6 1.1 1 0 0 1 1 1 1 ML domain Pex14_N PF04695.13 KII93575.1 - 1.1e-23 84.7 4.3 1.1e-23 84.7 4.3 3.3 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IFT57 PF10498.9 KII93575.1 - 5.4e-05 22.3 2.0 7.4e-05 21.9 2.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1664 PF07889.12 KII93575.1 - 6.1e-05 23.0 1.4 0.00013 22.0 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 KII93575.1 - 0.0029 15.6 0.0 0.0033 15.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Med9 PF07544.13 KII93575.1 - 0.0035 17.4 6.5 0.056 13.5 6.4 2.3 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF3584 PF12128.8 KII93575.1 - 0.004 14.8 9.9 0.0054 14.3 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7 PF08317.11 KII93575.1 - 0.0048 15.8 10.5 0.0072 15.3 10.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ING PF12998.7 KII93575.1 - 0.0048 17.5 4.5 0.0086 16.6 3.5 1.8 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Laminin_II PF06009.12 KII93575.1 - 0.0094 16.0 8.6 0.016 15.2 8.6 1.3 1 0 0 1 1 1 1 Laminin Domain II Golgin_A5 PF09787.9 KII93575.1 - 0.029 13.9 8.6 0.039 13.4 8.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KII93575.1 - 0.061 12.7 6.4 0.091 12.1 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KII93575.1 - 0.071 13.1 2.5 0.23 11.5 2.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LXG PF04740.12 KII93575.1 - 0.076 12.7 5.0 0.12 12.1 5.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily TPH PF13868.6 KII93575.1 - 0.078 11.5 15.9 0.1 11.1 15.9 1.1 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain NPV_P10 PF05531.12 KII93575.1 - 0.12 12.8 10.3 9.8 6.7 8.0 3.3 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein FIVAR PF07554.13 KII93575.1 - 0.13 13.1 4.3 1.2 9.9 2.7 2.4 2 0 0 2 2 2 0 FIVAR domain DUF3818 PF12825.7 KII93575.1 - 0.13 11.2 2.7 0.18 10.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) TMPIT PF07851.13 KII93575.1 - 0.15 11.3 4.0 0.24 10.6 4.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 KII93575.1 - 0.16 10.8 0.5 0.21 10.5 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 KII93575.1 - 0.17 10.4 4.9 0.37 9.3 4.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2431 PF10354.9 KII93575.1 - 0.19 12.0 0.1 0.29 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF4192 PF13830.6 KII93575.1 - 0.19 11.7 3.1 0.27 11.2 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AAA_13 PF13166.6 KII93575.1 - 0.22 10.1 7.3 0.3 9.7 7.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 KII93575.1 - 0.23 10.7 10.9 0.34 10.2 10.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2524 PF10732.9 KII93575.1 - 0.25 11.7 5.2 0.47 10.8 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Prominin PF05478.11 KII93575.1 - 0.25 9.2 2.1 0.34 8.8 2.1 1.1 1 0 0 1 1 1 0 Prominin MCPsignal PF00015.21 KII93575.1 - 0.33 10.8 7.4 0.7 9.7 7.4 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tektin PF03148.14 KII93575.1 - 0.33 9.7 12.8 0.89 8.2 12.8 1.6 1 1 0 1 1 1 0 Tektin family ISG65-75 PF11727.8 KII93575.1 - 0.39 9.9 8.6 0.56 9.4 8.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3138 PF11336.8 KII93575.1 - 0.53 8.8 1.9 0.7 8.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fib_alpha PF08702.10 KII93575.1 - 0.57 10.4 4.4 0.92 9.7 4.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BORCS8 PF10167.9 KII93575.1 - 0.71 9.8 3.8 1.3 9.0 2.7 2.0 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Mt_ATP-synt_D PF05873.12 KII93575.1 - 0.76 9.6 9.7 2.1 8.2 3.8 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) COG2 PF06148.11 KII93575.1 - 1.1 9.3 11.5 0.81 9.8 2.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1319 PF07028.11 KII93575.1 - 1.2 9.4 7.1 2.3 8.4 0.3 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1319) TSNAXIP1_N PF15739.5 KII93575.1 - 1.3 9.5 8.0 0.65 10.4 3.7 2.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus OmpH PF03938.14 KII93575.1 - 1.5 9.2 12.1 2.8 8.3 12.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 KII93575.1 - 1.8 8.9 9.0 8.2 6.8 1.9 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KII93575.1 - 1.9 9.0 14.9 3.8 8.0 14.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region THOC7 PF05615.13 KII93575.1 - 2.1 8.6 13.2 10 6.4 12.3 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 Zw10 PF06248.13 KII93575.1 - 2.2 6.7 5.9 3.1 6.2 5.9 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 AcylCoA_dehyd_C PF12186.8 KII93575.1 - 2.6 8.2 5.9 2.2 8.4 1.6 2.2 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal DLP_helical PF18709.1 KII93575.1 - 3.2 6.9 9.3 0.71 9.0 3.3 1.8 1 1 0 1 1 1 0 Dynamin-like helical domain HIP1_clath_bdg PF16515.5 KII93575.1 - 7.2 7.3 13.5 1.9 9.2 3.8 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 KII93575.1 - 7.7 7.1 9.3 98 3.5 9.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 YabA PF06156.13 KII93575.1 - 9.5 6.9 7.5 20 5.9 5.9 1.9 1 1 1 2 2 2 0 Initiation control protein YabA GTP_EFTU PF00009.27 KII93576.1 - 8e-56 188.7 0.3 1.2e-55 188.1 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KII93576.1 - 4.8e-28 97.7 1.1 6e-28 97.4 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KII93576.1 - 5.8e-16 58.6 2.9 1.8e-15 57.1 2.9 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII93576.1 - 0.00013 22.0 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII93576.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 KII93576.1 - 0.009 15.6 0.4 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KII93576.1 - 0.012 15.4 0.2 9.1 6.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FMN_bind_2 PF04299.12 KII93577.1 - 4.6e-59 198.9 0.1 5.4e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain GCV_H PF01597.19 KII93578.1 - 3.3e-38 130.3 0.0 4.3e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KII93578.1 - 0.0021 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KII93578.1 - 0.0087 15.9 0.4 0.017 14.9 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Tcell_CD4_C PF12104.8 KII93578.1 - 0.063 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region PTS_EIIA_1 PF00358.20 KII93578.1 - 0.12 12.2 0.2 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ESSS PF10183.9 KII93579.1 - 3.6e-12 46.4 0.0 3.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RIO1 PF01163.22 KII93580.1 - 2.7e-42 144.5 0.0 8e-30 103.8 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KII93580.1 - 1.1e-33 115.3 0.1 1.8e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KII93580.1 - 5e-07 29.9 0.5 0.00074 19.5 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KII93580.1 - 3.4e-06 26.6 0.1 4.7e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.12 KII93580.1 - 0.11 10.6 6.5 0.15 10.2 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KII93580.1 - 0.25 10.6 6.3 0.37 10.1 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KII93580.1 - 0.37 9.0 5.8 0.52 8.5 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KII93580.1 - 2.8 7.6 5.2 6.2 6.5 5.2 1.5 1 0 0 1 1 1 0 FAM176 family GP67 PF17634.2 KII93580.1 - 3.3 8.2 17.2 7.8 7.0 17.2 1.6 1 0 0 1 1 1 0 Gene product 67 DUF4278 PF14105.6 KII93581.1 - 0.00019 21.8 2.9 0.031 14.7 0.8 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4278) Polyketide_cyc2 PF10604.9 KII93581.1 - 0.00025 21.3 0.1 0.00075 19.8 0.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_23 PF13489.6 KII93581.1 - 0.21 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KII93582.1 - 0.00017 21.4 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93582.1 - 0.0017 19.0 0.0 0.0033 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII93582.1 - 0.014 16.1 0.0 0.035 14.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KII93582.1 - 0.016 15.9 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KII93582.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.25 KII93583.1 - 9.9e-16 58.0 0.0 1.4e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII93583.1 - 1.2e-10 41.4 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII93583.1 - 1.2e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII93583.1 - 7.1e-08 32.3 0.0 1.5e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KII93583.1 - 3.2e-06 27.4 0.0 4.6e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII93583.1 - 0.011 16.4 0.1 0.015 16.0 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KII93584.1 - 5.5e-55 183.3 2.4 4.9e-19 68.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 KII93585.1 - 2.6e-15 56.4 0.0 4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 PX domain Pyrophosphatase PF00719.19 KII93586.1 - 3.3e-60 202.5 0.2 4.2e-60 202.2 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase CFEM PF05730.11 KII93587.1 - 0.011 15.8 7.1 0.023 14.8 7.1 1.6 1 1 0 1 1 1 0 CFEM domain HTH_15 PF12324.8 KII93588.1 - 0.55 10.2 9.4 6.1 6.9 0.6 4.2 2 2 2 4 4 4 0 Helix-turn-helix domain of alkylmercury lyase Lin-8 PF03353.15 KII93590.1 - 0.017 14.7 2.7 0.022 14.3 2.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 KII93590.1 - 0.17 10.4 1.7 0.2 10.2 1.7 1.1 1 0 0 1 1 1 0 Macoilin family MAP65_ASE1 PF03999.12 KII93590.1 - 0.41 9.3 8.0 0.56 8.9 8.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) MCLC PF05934.11 KII93590.1 - 0.68 8.6 2.8 0.88 8.2 2.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RAP1 PF07218.11 KII93590.1 - 0.87 7.8 3.0 1 7.6 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 KII93590.1 - 0.98 8.4 8.2 1.9 7.5 8.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X CENP-T_C PF15511.6 KII93593.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KII93593.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KII93593.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KII93593.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII93593.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KII93593.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 KII93594.1 - 6.7e-25 87.1 0.0 8.9e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KII93594.1 - 1.6e-06 28.5 0.1 2.2e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KII93594.1 - 2.6e-05 24.5 0.0 0.0027 18.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 KII93594.1 - 0.0032 17.4 0.0 0.0082 16.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KII93594.1 - 0.0033 16.8 0.0 0.004 16.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KII93594.1 - 0.004 16.9 0.0 0.0051 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KII93594.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KII93594.1 - 0.024 14.5 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.10 KII93594.1 - 0.054 13.2 0.1 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Redoxin dsrm PF00035.26 KII93595.1 - 1.1e-10 42.1 0.1 3e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KII93595.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII93595.1 - 4.7e-05 24.0 0.1 0.00012 22.6 0.1 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Sporozoite_P67 PF05642.11 KII93596.1 - 0.024 12.7 0.4 0.035 12.2 0.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ndc1_Nup PF09531.10 KII93597.1 - 0.29 9.8 1.8 0.36 9.5 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MCLC PF05934.11 KII93597.1 - 0.77 8.4 2.8 1.1 7.9 2.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF966 PF06136.13 KII93598.1 - 0.013 15.3 0.1 0.014 15.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4687 PF15747.5 KII93599.1 - 0.15 12.5 0.2 0.25 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) Glyco_transf_22 PF03901.17 KII93600.1 - 6.5e-84 282.6 7.2 1.5e-83 281.4 7.2 1.6 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamin_N PF00350.23 KII93601.1 - 8.5e-17 61.7 0.0 3.8e-16 59.6 0.0 2.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KII93601.1 - 1.1e-10 41.6 0.5 1.8e-08 34.4 0.1 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KII93601.1 - 1.4e-05 25.6 0.1 0.00049 20.6 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.16 KII93601.1 - 0.0016 17.8 0.0 0.0038 16.6 0.0 1.7 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KII93601.1 - 0.0035 16.9 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_23 PF13476.6 KII93601.1 - 0.004 17.7 4.2 0.14 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KII93601.1 - 0.0054 16.9 4.3 0.006 16.7 0.0 3.1 4 1 0 4 4 4 1 Helicase HerA, central domain AAA_22 PF13401.6 KII93601.1 - 0.0085 16.4 0.4 0.16 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KII93601.1 - 0.013 14.8 1.0 0.05 13.0 0.2 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KII93601.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KII93601.1 - 0.029 14.3 0.0 0.097 12.6 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 KII93601.1 - 0.042 13.4 0.2 9.2 5.8 0.0 2.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 KII93601.1 - 0.045 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KII93601.1 - 0.096 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 KII93601.1 - 0.11 12.7 0.1 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KII93601.1 - 0.2 12.1 1.7 1.7 9.0 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain DivIC PF04977.15 KII93601.1 - 0.2 11.5 2.8 0.84 9.5 2.8 2.2 1 0 0 1 1 1 0 Septum formation initiator Spore_II_R PF09551.10 KII93601.1 - 1.2 9.6 5.2 27 5.2 0.0 3.4 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) F-box-like PF12937.7 KII93602.1 - 1.1e-09 38.1 0.2 2.2e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII93602.1 - 3.3e-08 33.2 0.1 6.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KII93602.1 - 0.00027 20.8 1.0 0.002 18.0 0.0 2.2 1 1 1 2 2 2 1 F-box PRANC PF09372.10 KII93602.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 PRANC domain CutC PF03932.14 KII93603.1 - 1.1e-56 191.5 0.2 1.4e-56 191.2 0.2 1.1 1 0 0 1 1 1 1 CutC family FA_desaturase PF00487.24 KII93604.1 - 1.4e-06 28.3 11.4 1.4e-06 28.3 11.4 2.6 2 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII93604.1 - 0.0014 18.8 0.0 0.0054 16.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Bromodomain PF00439.25 KII93605.1 - 3.7e-35 119.9 4.4 9.8e-18 64.0 0.6 2.3 2 0 0 2 2 2 2 Bromodomain Tristanin_u2 PF16638.5 KII93605.1 - 0.1 13.4 7.9 0.35 11.7 7.9 1.9 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers DHHC PF01529.20 KII93606.1 - 2.1e-36 125.0 6.3 2.1e-36 125.0 6.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KII93606.1 - 0.13 12.1 0.5 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF588 PF04535.12 KII93606.1 - 0.15 11.8 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF588) NRIP1_repr_3 PF15689.5 KII93607.1 - 0.064 13.6 0.6 0.064 13.6 0.6 2.7 1 1 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 PEHE PF15275.6 KII93608.1 - 2.2e-05 25.1 1.5 2.2e-05 25.1 1.5 2.2 2 1 1 3 3 3 1 PEHE domain SAS4 PF15460.6 KII93608.1 - 0.00012 22.1 4.8 0.00033 20.7 4.8 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF4726 PF15855.5 KII93608.1 - 0.028 14.6 1.0 0.77 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) SIN1 PF05422.12 KII93608.1 - 0.15 12.6 4.1 0.1 13.2 0.7 2.3 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) ACT_7 PF13840.6 KII93609.1 - 1.2e-19 69.8 0.0 1.9e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 ACT domain Ribonuclease_T2 PF00445.18 KII93610.1 - 3.2e-39 135.0 0.0 5e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family TRI5 PF06330.11 KII93611.1 - 4.6e-25 88.3 0.0 6.1e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF1722 PF08349.11 KII93611.1 - 0.051 13.8 0.0 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Ribonuclease_T2 PF00445.18 KII93612.1 - 7.8e-40 137.0 0.0 1.2e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Gar1 PF04410.14 KII93613.1 - 1.9e-34 118.7 0.6 3.3e-34 117.9 0.6 1.4 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region EF_TS PF00889.19 KII93614.1 - 1.2e-16 60.9 0.0 3.5e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor TS HOIP-UBA PF16678.5 KII93614.1 - 0.096 12.7 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair UBA PF00627.31 KII93614.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Ceramidase PF05875.12 KII93615.1 - 8.4e-83 277.8 7.4 1e-82 277.6 7.4 1.0 1 0 0 1 1 1 1 Ceramidase HA2 PF04408.23 KII93616.1 - 7.4e-18 64.8 0.4 2e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KII93616.1 - 1.9e-13 50.5 0.0 3.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KII93616.1 - 8.3e-12 45.4 0.0 2.5e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII93616.1 - 2e-08 34.2 0.1 3.8e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KII93616.1 - 0.00037 20.8 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KII93616.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KII93616.1 - 0.068 13.7 0.0 0.25 11.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KII93616.1 - 0.078 12.0 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 KII93616.1 - 0.083 12.8 0.7 0.37 10.7 0.3 2.3 2 1 0 2 2 2 0 NACHT domain ResIII PF04851.15 KII93616.1 - 0.1 12.6 0.0 0.95 9.4 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KII93616.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC OB_NTP_bind PF07717.16 KII93617.1 - 5.6e-25 87.5 0.0 1.1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KII93617.1 - 1.6e-24 86.2 0.7 4e-24 85.0 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KII93617.1 - 1.7e-13 50.9 0.0 5.8e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KII93617.1 - 1.5e-06 28.4 0.2 3.4e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KII93617.1 - 8.9e-06 25.6 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KII93617.1 - 0.0018 17.4 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KII93617.1 - 0.0019 18.7 0.1 0.94 10.0 0.0 2.7 1 1 1 2 2 2 1 ABC transporter AAA_22 PF13401.6 KII93617.1 - 0.003 17.8 0.0 0.0091 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KII93617.1 - 0.0058 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KII93617.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KII93617.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3502 PF12010.8 KII93617.1 - 0.14 12.8 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) NTF2 PF02136.20 KII93618.1 - 9.9e-12 45.5 0.0 3.5e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KII93618.1 - 2e-08 34.3 0.0 2.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.23 KII93619.1 - 7.7e-20 71.4 0.2 1e-19 71.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinocilin PF15033.6 KII93619.1 - 0.033 13.8 0.0 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Kinocilin protein Abhydrolase_3 PF07859.13 KII93620.1 - 2.4e-47 161.5 0.0 3.9e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII93620.1 - 2.7e-15 56.1 0.0 2.6e-13 49.6 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KII93620.1 - 0.0076 16.9 1.9 0.0076 16.9 1.9 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII93620.1 - 0.036 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KII93620.1 - 0.055 12.3 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_M24 PF00557.24 KII93622.1 - 3.7e-39 134.6 0.1 4.5e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CENP-T_C PF15511.6 KII93623.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KII93623.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KII93623.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KII93623.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KII93623.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KII93623.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.17 KII93624.1 - 1e-28 100.6 0.0 1.6e-28 99.9 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain RcnB PF11776.8 KII93624.1 - 0.2 11.7 0.8 1.8 8.7 0.3 2.4 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator RhoGEF PF00621.20 KII93626.1 - 8.3e-13 49.0 0.0 1e-09 38.9 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Macoilin PF09726.9 KII93626.1 - 7.3 5.0 4.9 10 4.5 4.9 1.1 1 0 0 1 1 1 0 Macoilin family NIF PF03031.18 KII93627.1 - 1.1e-23 83.7 0.0 7.3e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KII93627.1 - 5e-08 32.8 0.2 3.9e-07 29.9 0.2 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KII93627.1 - 4.4e-05 23.8 0.0 8.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KII93627.1 - 0.027 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BSP PF04450.12 KII93628.1 - 5e-60 202.8 0.0 5.8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF3168 PF11367.8 KII93628.1 - 0.21 11.8 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) SnoaL_2 PF12680.7 KII93629.1 - 0.043 14.5 0.1 0.09 13.4 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain Zn_clus PF00172.18 KII93630.1 - 1.2e-07 31.7 4.4 1.8e-07 31.1 4.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 KII93630.1 - 0.034 14.1 4.1 0.061 13.3 4.1 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c FixQ PF05545.11 KII93630.1 - 0.21 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Haem_bd PF14376.6 KII93630.1 - 0.4 10.6 2.9 0.72 9.8 2.9 1.4 1 0 0 1 1 1 0 Haem-binding domain Spt20 PF12090.8 KII93630.1 - 7.3 6.1 18.6 14 5.2 18.6 1.4 1 0 0 1 1 1 0 Spt20 family HLH PF00010.26 KII93631.1 - 5e-05 23.2 0.0 9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SOG2 PF10428.9 KII93631.1 - 1.5 7.9 7.3 1.8 7.7 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 KII93632.1 - 0.026 13.2 15.7 0.039 12.6 15.7 1.1 1 0 0 1 1 1 0 Hamartin protein Myc_N PF01056.18 KII93632.1 - 0.29 11.0 12.7 0.52 10.2 12.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CytochromB561_N PF09786.9 KII93632.1 - 2.2 7.1 14.4 4.4 6.2 14.4 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.25 KII93633.1 - 1.8e-65 220.9 0.0 3.1e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93633.1 - 8.2e-35 120.3 0.0 3.3e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KII93633.1 - 7.3e-06 25.5 0.1 5.5e-05 22.6 0.1 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KII93633.1 - 3.7e-05 23.8 1.1 0.0035 17.3 0.0 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII93633.1 - 0.0021 16.9 0.1 0.0053 15.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KII93633.1 - 0.013 14.6 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 KII93633.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MMR_HSR1_Xtn PF16897.5 KII93634.1 - 1.8e-42 143.7 0.4 3e-42 143.0 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KII93634.1 - 1.7e-19 70.0 0.0 3.6e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KII93634.1 - 6.3e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KII93634.1 - 1.5e-10 40.8 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KII93634.1 - 0.0091 16.1 0.1 0.27 11.3 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MCM PF00493.23 KII93634.1 - 0.09 11.9 0.0 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 KII93634.1 - 0.097 13.0 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Lactamase_B_2 PF12706.7 KII93635.1 - 9.8e-24 84.0 0.0 1.1e-15 57.7 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KII93635.1 - 7.2e-05 22.9 0.3 7.2e-05 22.9 0.3 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Hist_deacetyl PF00850.19 KII93636.1 - 3.9e-85 286.0 0.0 5.9e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain IRK_N PF08466.10 KII93636.1 - 0.012 15.8 0.4 0.031 14.4 0.4 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel N-terminal NIL PF09383.10 KII93636.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 NIL domain DinB_2 PF12867.7 KII93637.1 - 1.6e-08 35.1 0.8 2.1e-08 34.7 0.8 1.2 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 KII93637.1 - 0.0065 16.4 0.2 0.012 15.6 0.2 1.4 1 1 0 1 1 1 1 DinB family EpmC PF04315.12 KII93637.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor P hydroxylase YycC PF14174.6 KII93637.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 YycC-like protein ATP-grasp_2 PF08442.10 KII93638.1 - 1.2e-71 240.5 1.5 1.3e-71 240.3 0.4 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KII93638.1 - 1e-26 93.6 0.1 2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KII93638.1 - 1.1e-09 38.0 0.2 6.9e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KII93638.1 - 0.0002 21.2 0.1 0.00088 19.1 0.1 2.0 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF5401 PF17380.2 KII93639.1 - 1.6 6.7 11.7 3.6 5.5 11.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5401) BCAS2 PF05700.11 KII93640.1 - 8.5e-68 228.1 5.8 9.6e-68 227.9 5.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 KII93640.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor Baculo_PEP_C PF04513.12 KII93640.1 - 0.044 13.8 2.3 0.085 12.9 2.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 KII93640.1 - 0.089 13.1 2.7 0.18 12.2 2.7 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein SOAR PF16533.5 KII93640.1 - 0.13 12.3 2.9 0.2 11.7 0.2 2.5 2 1 0 3 3 3 0 STIM1 Orai1-activating region LRR_RI_capping PF18779.1 KII93640.1 - 0.13 11.9 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Complex1_30kDa PF00329.19 KII93641.1 - 1.4e-45 154.9 0.0 2e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF5427 PF10310.9 KII93642.1 - 8.2e-62 209.7 7.2 1.4e-57 195.7 0.1 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5427) DUF4123 PF13503.6 KII93642.1 - 0.021 15.3 0.3 0.04 14.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Pol_alpha_B_N PF08418.10 KII93642.1 - 1.4 8.8 4.7 0.22 11.5 0.8 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal TFIIF_alpha PF05793.12 KII93643.1 - 0.33 9.5 29.2 0.48 8.9 29.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CSRNP_N PF16019.5 KII93643.1 - 6.6 6.6 7.9 9.9 6.0 7.9 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Tim17 PF02466.19 KII93644.1 - 3.1e-14 53.3 1.5 3.2e-14 53.2 0.6 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 KII93644.1 - 0.088 13.4 0.5 0.13 12.9 0.5 1.2 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF5518 PF17647.1 KII93644.1 - 0.31 11.2 3.3 9.6 6.4 0.1 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5518) Ras PF00071.22 KII93646.1 - 5e-51 172.5 0.1 5.8e-51 172.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII93646.1 - 1.2e-18 67.4 0.0 2.7e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII93646.1 - 6.9e-05 22.4 0.0 7.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII93646.1 - 0.00044 19.8 0.1 0.0017 18.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII93646.1 - 0.0016 18.4 0.0 0.093 12.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KII93646.1 - 0.0084 15.6 0.1 0.34 10.4 0.0 2.6 1 1 2 3 3 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KII93646.1 - 0.046 13.8 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KII93646.1 - 0.15 12.5 0.3 0.54 10.6 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain Oxidored_FMN PF00724.20 KII93648.1 - 2.4e-22 79.7 0.4 4.4e-22 78.8 0.3 1.4 2 0 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Methyltransf_23 PF13489.6 KII93649.1 - 6.8e-15 55.3 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII93649.1 - 7.7e-13 49.0 0.0 1.5e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII93649.1 - 6.3e-11 42.8 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII93649.1 - 2.3e-09 37.3 0.0 2.1e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93649.1 - 3.4e-07 30.9 0.0 2.2e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KII93649.1 - 7.7e-05 21.4 0.0 0.0006 18.5 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KII93649.1 - 0.00031 20.3 0.0 0.004 16.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 KII93649.1 - 0.00037 19.9 0.0 0.0022 17.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KII93649.1 - 0.00038 19.9 0.0 0.001 18.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KII93649.1 - 0.00073 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 KII93649.1 - 0.002 17.5 0.0 0.025 13.9 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KII93649.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 KII93649.1 - 0.007 16.2 0.0 0.029 14.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF938) SCVP PF17619.2 KII93651.1 - 0.026 15.4 0.2 3.1 8.7 0.1 2.1 1 1 1 2 2 2 0 Secreted clade V proteins Histone_HNS PF00816.21 KII93651.1 - 0.6 11.0 9.5 0.13 13.1 6.4 1.5 2 0 0 2 2 2 0 H-NS histone family Ribonuc_red_sm PF00268.21 KII93652.1 - 1.4e-107 359.3 0.0 1.6e-107 359.1 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain EKLF_TAD2 PF16833.5 KII93653.1 - 0.016 15.2 0.2 0.042 13.9 0.2 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 2 DUF1495 PF07381.11 KII93654.1 - 0.065 13.1 0.1 1.2 9.1 0.1 2.4 2 1 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) F-box-like PF12937.7 KII93657.1 - 1.7e-06 27.8 0.8 1.5e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII93657.1 - 1.7e-05 24.6 2.6 3.2e-05 23.7 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_2 PF07723.13 KII93657.1 - 0.11 13.3 0.0 0.39 11.5 0.0 2.1 1 0 0 1 1 1 0 Leucine Rich Repeat F-box_4 PF15966.5 KII93657.1 - 1.3 8.9 4.5 0.5 10.3 0.1 2.4 2 1 1 3 3 3 0 F-box Pkinase PF00069.25 KII93658.1 - 9.9e-36 123.4 0.0 1.3e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93658.1 - 9.8e-10 38.1 0.0 3.5e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KII93658.1 - 0.0027 16.7 0.1 0.0053 15.8 0.1 1.4 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KII93658.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KII93660.1 - 3.9e-08 33.0 0.0 2.7e-07 30.2 0.0 1.9 1 1 1 2 2 2 2 Protein kinase domain Yippee-Mis18 PF03226.14 KII93662.1 - 7.1e-16 58.3 1.0 7.9e-16 58.2 1.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-UBR PF02207.20 KII93662.1 - 0.0092 16.1 1.1 2 8.7 0.3 2.2 2 0 0 2 2 2 2 Putative zinc finger in N-recognin (UBR box) RIG-I_C-RD PF11648.8 KII93662.1 - 0.053 13.8 0.4 0.077 13.2 0.4 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I AlcCBM31 PF11606.8 KII93662.1 - 0.08 13.1 0.1 11 6.2 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein Peptidase_C48 PF02902.19 KII93665.1 - 1.3e-36 126.5 0.7 2.6e-34 119.0 0.7 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Use1 PF09753.9 KII93666.1 - 0.002 17.9 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 KII93666.1 - 0.047 13.6 0.1 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Sec20 DUF1772 PF08592.11 KII93667.1 - 1.1 9.6 5.0 1 9.7 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) TMEMspv1-c74-12 PF11044.8 KII93667.1 - 8.4 6.5 11.3 3.6 7.6 0.5 3.8 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PTH2 PF01981.16 KII93668.1 - 2.2e-39 134.4 0.0 2.7e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PgaD PF13994.6 KII93668.1 - 0.14 12.2 0.4 0.24 11.5 0.2 1.5 1 1 1 2 2 2 0 PgaD-like protein Sgf11 PF08209.11 KII93669.1 - 2.1e-14 52.8 0.4 3.6e-14 52.0 0.4 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Fungal_trans PF04082.18 KII93670.1 - 7.3e-29 100.6 0.0 1.4e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII93670.1 - 1.2e-06 28.5 9.5 2.3e-06 27.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.19 KII93670.1 - 0.77 9.9 4.4 1.5 8.9 4.4 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family NIPSNAP PF07978.13 KII93671.1 - 5.8e-31 106.8 2.4 2.6e-26 91.8 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP F5_F8_type_C PF00754.25 KII93672.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain Proteasome PF00227.26 KII93673.1 - 2.6e-38 131.4 0.0 3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KII93673.1 - 0.048 13.7 0.0 0.76 9.9 0.1 2.3 2 0 0 2 2 2 0 Phage late-transcription coactivator MoaC PF01967.21 KII93674.1 - 9.9e-48 161.7 1.4 2.2e-47 160.6 1.4 1.6 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KII93674.1 - 8e-34 116.3 0.0 1.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KII93674.1 - 3.6e-25 89.3 0.0 6.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KII93674.1 - 2e-07 31.4 0.0 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KII93674.1 - 0.00048 20.3 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain HpcH_HpaI PF03328.14 KII93675.1 - 1.5e-31 109.3 0.0 1.9e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KII93675.1 - 0.03 13.2 0.3 0.05 12.5 0.3 1.4 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain FR47 PF08445.10 KII93676.1 - 9.3e-08 31.9 0.1 1.9e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KII93676.1 - 3.7e-07 30.4 0.1 6.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII93676.1 - 3.9e-07 30.0 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII93676.1 - 6.5e-06 26.5 0.1 1.2e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII93676.1 - 0.0004 20.5 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KII93676.1 - 0.0097 16.0 0.0 0.026 14.6 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF953 PF06110.11 KII93677.1 - 3.6e-20 71.7 0.0 4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Mucin PF01456.17 KII93678.1 - 4.9 7.1 24.1 4.4 7.3 9.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Mito_carr PF00153.27 KII93679.1 - 3.4e-62 206.4 0.5 3e-22 78.3 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KII93679.1 - 1.7e-16 60.4 3.3 6.3e-07 29.8 0.1 5.0 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 KII93679.1 - 1.7e-14 52.2 3.4 2.4e-05 23.6 0.1 5.7 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 KII93679.1 - 2.9e-14 51.7 1.8 0.00034 20.3 0.1 5.9 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.6 KII93679.1 - 9.9e-10 38.1 4.0 0.0058 16.4 0.0 5.0 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 KII93679.1 - 1.8e-08 33.5 3.7 0.00035 19.9 0.0 4.0 4 0 0 4 4 4 2 EF hand Met_10 PF02475.16 KII93680.1 - 5.8e-66 222.0 0.0 7.4e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KII93680.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TatD_DNase PF01026.21 KII93681.1 - 7.6e-22 77.9 0.0 1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.8 KII93682.1 - 1.1e-14 54.5 1.7 1.1e-14 54.5 1.7 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus CK2S PF15011.6 KII93682.1 - 0.0044 16.9 0.5 0.014 15.3 0.1 1.9 2 0 0 2 2 2 1 Casein Kinase 2 substrate AAA_13 PF13166.6 KII93682.1 - 0.0073 15.0 0.8 0.0089 14.7 0.8 1.0 1 0 0 1 1 1 1 AAA domain CCDC-167 PF15188.6 KII93682.1 - 0.035 14.4 1.7 3.5 8.0 0.5 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 kleA_kleC PF17383.2 KII93682.1 - 0.042 14.2 2.1 0.053 13.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A DUF4201 PF13870.6 KII93682.1 - 0.05 13.3 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TipAS PF07739.13 KII93682.1 - 0.052 14.1 0.5 0.13 12.9 0.5 1.8 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain XhlA PF10779.9 KII93682.1 - 0.084 13.1 1.7 0.11 12.7 0.5 1.9 2 0 0 2 2 2 0 Haemolysin XhlA Sec20 PF03908.13 KII93682.1 - 0.11 12.4 0.8 0.41 10.6 0.0 2.2 3 0 0 3 3 3 0 Sec20 DUF3678 PF12435.8 KII93682.1 - 0.17 11.3 2.6 0.48 9.8 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) V_ATPase_I PF01496.19 KII93682.1 - 0.17 9.7 1.7 0.29 9.0 0.4 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family AbiH PF14253.6 KII93682.1 - 0.23 11.3 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH CorA PF01544.18 KII93682.1 - 3.2 7.0 8.6 0.28 10.4 0.4 2.4 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein B-block_TFIIIC PF04182.12 KII93683.1 - 9.5e-08 32.1 0.1 2.3e-06 27.7 0.1 2.9 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR PF01047.22 KII93683.1 - 0.017 15.1 0.2 0.7 9.9 0.0 3.3 3 0 0 3 3 3 0 MarR family MarR_2 PF12802.7 KII93683.1 - 0.027 14.4 0.0 1.2 9.1 0.0 3.1 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 KII93683.1 - 0.047 13.3 1.7 0.29 10.7 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_micro PF17007.5 KII93683.1 - 0.078 11.8 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 HTH-like PRELI PF04707.14 KII93684.1 - 4.8e-37 127.2 0.0 5.7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ABC_membrane_2 PF06472.15 KII93685.1 - 2.8e-83 279.4 0.3 4e-83 278.9 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KII93685.1 - 7.7e-17 62.1 0.0 1.5e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII93685.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KII93685.1 - 0.0034 17.9 0.4 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII93685.1 - 0.031 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KII93685.1 - 0.043 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 KII93685.1 - 0.049 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_27 PF13514.6 KII93685.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KII93685.1 - 0.096 13.1 0.6 0.29 11.5 0.2 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KII93685.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 KII93685.1 - 0.22 11.2 0.5 0.39 10.4 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF641 PF04859.12 KII93686.1 - 1.5e-05 25.3 18.9 0.15 12.4 0.1 5.1 2 1 2 4 4 4 2 Plant protein of unknown function (DUF641) MAD PF05557.13 KII93686.1 - 0.0019 16.7 24.7 0.0025 16.3 24.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein CEP63 PF17045.5 KII93686.1 - 0.0023 17.9 6.0 0.0023 17.9 6.0 3.7 1 1 2 4 4 4 1 Centrosomal protein of 63 kDa Atg14 PF10186.9 KII93686.1 - 0.0028 16.8 18.9 0.027 13.6 7.6 2.6 1 1 2 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 KII93686.1 - 0.0045 17.2 27.5 2.7 8.2 2.0 4.5 1 1 3 4 4 4 2 TATA element modulatory factor 1 TATA binding LURAP PF14854.6 KII93686.1 - 0.0057 16.6 9.4 0.3 11.0 0.2 4.0 1 1 4 5 5 5 1 Leucine rich adaptor protein CALCOCO1 PF07888.11 KII93686.1 - 0.0096 14.8 26.7 0.017 14.1 26.7 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 KII93686.1 - 0.013 16.0 25.1 0.14 12.6 17.1 2.9 1 1 2 3 3 3 0 Fez1 HlyD_2 PF12700.7 KII93686.1 - 0.016 13.9 1.8 0.62 8.7 0.1 2.1 2 0 0 2 2 2 0 HlyD family secretion protein TMF_DNA_bd PF12329.8 KII93686.1 - 0.05 13.6 26.1 0.033 14.2 7.6 4.1 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KII93686.1 - 0.053 13.9 23.5 4 7.9 2.2 6.1 2 2 4 6 6 6 0 Csm1 N-terminal domain HR1 PF02185.16 KII93686.1 - 0.064 13.4 0.6 0.064 13.4 0.6 5.5 3 1 3 6 6 5 0 Hr1 repeat ATG16 PF08614.11 KII93686.1 - 0.4 10.9 38.4 0.4 10.9 9.6 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KII93686.1 - 0.63 9.4 21.8 0.03 13.7 9.8 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 KII93686.1 - 0.64 9.8 10.7 0.15 11.9 2.9 2.6 1 1 1 2 2 2 0 Spindle Pole Component 29 ERM PF00769.19 KII93686.1 - 0.72 9.6 25.9 1.6 8.5 1.3 3.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Phage_GP20 PF06810.11 KII93686.1 - 0.74 9.6 13.7 0.67 9.8 1.7 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 KII93686.1 - 0.76 10.2 11.9 15 6.0 2.7 4.4 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 KII93686.1 - 1.3 8.0 16.4 0.89 8.5 8.1 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 KII93686.1 - 2.3 7.0 26.1 5.2 5.9 19.5 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KII93686.1 - 2.4 8.1 21.3 1.8 8.5 0.1 5.8 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Tup_N PF08581.10 KII93686.1 - 3 8.2 14.6 3.1 8.2 0.3 4.1 3 1 1 4 4 4 0 Tup N-terminal Occludin_ELL PF07303.13 KII93686.1 - 3.1 8.6 7.8 1.5 9.6 1.1 2.8 1 1 0 2 2 2 0 Occludin homology domain NPV_P10 PF05531.12 KII93686.1 - 4.1 7.9 8.5 32 5.1 2.6 4.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein CheY-binding PF09078.11 KII93686.1 - 8 6.7 7.6 35 4.6 0.9 3.5 2 1 1 3 3 3 0 CheY binding DUF5082 PF16888.5 KII93686.1 - 8.1 6.8 11.6 1.3 9.4 3.6 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) NT5C PF06941.12 KII93688.1 - 8.6e-09 35.5 0.6 4.4e-08 33.2 0.0 2.2 2 1 1 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.7 KII93688.1 - 0.0003 21.2 0.0 0.00047 20.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KII93688.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KII93688.1 - 0.0099 16.0 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 KII93688.1 - 0.012 15.3 0.0 0.041 13.6 0.0 1.8 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 KII93688.1 - 0.024 14.2 0.1 0.077 12.6 0.1 1.7 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase PF00702.26 KII93688.1 - 0.18 12.1 0.0 0.6 10.4 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase SecY PF00344.20 KII93689.1 - 1.3e-73 248.0 9.2 1.6e-73 247.7 9.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KII93689.1 - 2.7e-19 68.7 0.1 2.2e-18 65.8 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p DUF805 PF05656.14 KII93689.1 - 0.83 10.1 4.3 0.77 10.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Pro_CA PF00484.19 KII93690.1 - 2.7e-11 44.0 0.1 7.7e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 Carbonic anhydrase RINT1_TIP1 PF04437.13 KII93691.1 - 1.5e-89 301.2 0.0 6.2e-89 299.2 0.0 1.9 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Las1 PF04031.13 KII93691.1 - 0.061 13.4 0.2 0.29 11.2 0.0 2.2 2 1 0 2 2 2 0 Las1-like GrpE PF01025.19 KII93691.1 - 0.12 12.0 1.3 0.29 10.8 1.3 1.6 1 0 0 1 1 1 0 GrpE WASH-7_mid PF14744.6 KII93691.1 - 0.19 10.8 0.6 0.91 8.5 0.0 1.9 2 0 0 2 2 2 0 WASH complex subunit 7 ERM PF00769.19 KII93691.1 - 5.9 6.6 10.8 35 4.1 11.0 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Kinesin PF00225.23 KII93692.1 - 3.5e-80 269.4 0.0 5.7e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII93692.1 - 1.9e-15 57.1 0.0 1.5e-11 44.4 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding Egg_lysin PF01303.17 KII93692.1 - 0.068 13.4 0.1 5.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) Spc7 PF08317.11 KII93693.1 - 7.6e-85 284.5 8.6 1.1e-84 284.0 8.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KII93693.1 - 7.1e-07 29.2 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Spc7_C2 FTA4 PF13093.6 KII93693.1 - 0.047 13.6 1.7 0.2 11.5 2.0 1.9 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4315 PF14193.6 KII93693.1 - 0.13 12.3 5.2 9 6.4 2.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) RasGAP_C PF03836.15 KII93693.1 - 0.59 10.3 4.8 1.2 9.3 4.8 1.4 1 0 0 1 1 1 0 RasGAP C-terminus FapA PF03961.13 KII93693.1 - 0.75 8.3 6.5 1.2 7.6 6.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 KII93693.1 - 3.6 8.3 11.4 0.85 10.3 4.3 3.4 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 KII93693.1 - 6.1 6.9 5.1 61 3.7 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CD225 PF04505.12 KII93694.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein LMBR1 PF04791.16 KII93694.1 - 0.66 8.8 2.8 0.96 8.3 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DIE2_ALG10 PF04922.12 KII93695.1 - 5.9e-126 420.9 10.0 7.1e-126 420.7 10.0 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family TauD PF02668.16 KII93696.1 - 4.8e-54 184.0 0.5 5.8e-54 183.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Methyltransf_2 PF00891.18 KII93697.1 - 2.8e-24 85.6 0.0 1.7e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII93697.1 - 0.0056 16.5 0.0 0.022 14.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII93697.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KII93697.1 - 0.12 13.1 0.0 2.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Transp_cyt_pur PF02133.15 KII93698.1 - 4.9e-83 279.4 33.8 5.7e-83 279.1 33.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2970 PF11174.8 KII93698.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) OPT PF03169.15 KII93700.1 - 7.2e-182 606.3 56.1 8.2e-182 606.1 56.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2418 PF10332.9 KII93700.1 - 0.017 15.6 0.1 0.39 11.3 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF4229 PF14012.6 KII93700.1 - 8.2 6.6 14.2 2.3 8.4 4.6 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Prp19 PF08606.11 KII93701.1 - 3.2e-32 110.3 1.9 7.2e-32 109.2 1.9 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KII93701.1 - 7.4e-12 45.6 2.8 0.00031 21.5 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII93701.1 - 1.7e-09 37.8 0.0 0.0034 17.6 0.0 5.0 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 KII93701.1 - 6.2e-06 26.3 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KII93701.1 - 5.9e-05 22.8 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KII93701.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Frtz PF11768.8 KII93701.1 - 0.028 12.7 0.0 0.045 12.1 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Rtf2 PF04641.12 KII93701.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Cep57_MT_bd PF06657.13 KII93701.1 - 0.11 12.9 0.5 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PT-TG PF14449.6 KII93701.1 - 0.16 11.9 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 Pre-toxin TG TPR_1 PF00515.28 KII93702.1 - 3.5e-13 48.8 0.0 1.6e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KII93702.1 - 3.2e-10 39.7 0.2 0.0013 19.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII93702.1 - 3.6e-09 36.0 0.0 6.5e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII93702.1 - 6.1e-08 32.2 0.5 0.0098 15.6 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KII93702.1 - 4.8e-07 29.5 0.0 0.0036 17.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KII93702.1 - 4.7e-05 23.1 0.2 0.0033 17.4 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII93702.1 - 6.9e-05 23.3 0.1 0.0075 17.0 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII93702.1 - 9.6e-05 22.8 0.2 0.0012 19.3 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat STI1 PF17830.1 KII93702.1 - 0.00023 21.1 11.7 0.22 11.5 8.3 3.3 2 1 0 3 3 3 2 STI1 domain TPR_16 PF13432.6 KII93702.1 - 0.00052 20.6 3.4 0.0045 17.6 1.1 2.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII93702.1 - 0.0037 17.5 0.9 0.1 12.9 0.9 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII93702.1 - 0.11 12.7 0.1 0.28 11.3 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 KII93703.1 - 1.4e-33 114.9 10.9 6.8e-12 45.4 0.1 3.7 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII93703.1 - 3e-27 94.6 0.6 1.8e-12 47.3 0.1 3.8 2 1 2 4 4 4 3 Myb-like DNA-binding domain zf-C2H2_aberr PF17017.5 KII93703.1 - 4.6e-05 23.6 0.4 0.019 15.1 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger SANT_DAMP1_like PF16282.5 KII93703.1 - 9.8e-05 22.5 0.0 0.19 11.9 0.0 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 zf-C2H2_4 PF13894.6 KII93703.1 - 0.0077 17.0 4.2 8.3 7.6 0.1 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger SLIDE PF09111.10 KII93703.1 - 0.015 15.4 0.0 9.3 6.3 0.0 3.1 2 1 1 3 3 3 0 SLIDE zf-C2H2 PF00096.26 KII93703.1 - 0.024 15.1 2.2 0.81 10.3 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Rap1_C PF11626.8 KII93703.1 - 0.18 11.9 4.0 39 4.4 4.0 3.2 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain WD40 PF00400.32 KII93704.1 - 1.2e-31 108.2 14.6 9e-08 32.7 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII93704.1 - 2.4e-09 37.3 0.2 0.24 11.7 0.1 4.5 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KII93704.1 - 0.00024 20.7 0.0 0.055 13.0 0.0 2.6 2 1 1 3 3 3 3 PQQ-like domain Cytochrom_D1 PF02239.16 KII93704.1 - 0.015 13.9 0.0 1.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KII93704.1 - 0.085 12.8 0.5 5.9 7.0 0.2 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MCM PF00493.23 KII93706.1 - 2.2e-96 321.3 0.0 3.9e-96 320.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KII93706.1 - 9.6e-35 119.2 0.0 1.7e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KII93706.1 - 8.6e-22 77.4 0.2 1.9e-21 76.3 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KII93706.1 - 1.1e-15 58.1 0.4 3.1e-15 56.6 0.4 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KII93706.1 - 5.9e-08 32.3 0.0 1.4e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KII93706.1 - 0.0031 17.4 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KII93706.1 - 0.007 16.1 0.1 0.037 13.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2052 PF09747.9 KII93706.1 - 0.05 13.7 3.3 0.082 13.0 3.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_5 PF07728.14 KII93706.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MTS PF05175.14 KII93707.1 - 1.7e-05 24.4 0.0 0.00026 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain NVEALA PF14055.6 KII93707.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 NVEALA protein C2 PF00168.30 KII93708.1 - 1.9e-88 291.5 5.8 5.2e-18 65.2 0.1 6.1 7 0 0 7 7 7 5 C2 domain MLVIN_C PF18697.1 KII93708.1 - 0.036 14.2 0.1 0.66 10.1 0.0 2.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Mito_carr PF00153.27 KII93709.1 - 1.4e-20 73.0 0.0 1.9e-05 24.5 0.0 4.8 4 1 0 4 4 4 4 Mitochondrial carrier protein GOLD_2 PF13897.6 KII93709.1 - 0.13 12.7 0.3 0.24 11.9 0.3 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FAM176 PF14851.6 KII93709.1 - 0.19 11.4 0.7 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 FAM176 family NUDIX PF00293.28 KII93710.1 - 3.1e-06 27.3 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 KII93711.1 - 4.5e-51 173.7 0.0 9.6e-51 172.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93711.1 - 2.8e-39 135.0 0.0 1.9e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII93711.1 - 1.6e-06 27.2 0.0 2.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII93711.1 - 0.034 14.1 0.2 0.62 9.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KII93711.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 2 0 0 2 2 2 0 Kinase-like MitMem_reg PF13012.6 KII93712.1 - 6.4e-26 91.0 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KII93712.1 - 1.5e-12 47.5 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4149 PF13664.6 KII93713.1 - 7.5e-19 67.9 2.4 7.5e-19 67.9 2.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KII93713.1 - 0.0051 17.1 0.3 0.007 16.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) G0-G1_switch_2 PF15103.6 KII93713.1 - 0.16 12.4 0.1 0.28 11.6 0.1 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 LRR_9 PF14580.6 KII93714.1 - 5.2e-61 205.2 0.2 8.3e-61 204.5 0.1 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KII93714.1 - 1.8e-09 37.7 13.1 1.4e-06 28.5 3.8 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII93714.1 - 4.1e-08 32.9 2.0 2.6e-07 30.3 2.8 2.0 2 0 0 2 2 2 1 Leucine rich repeat Syja_N PF02383.18 KII93715.1 - 5.7e-86 288.7 0.0 7.6e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF2135 PF09906.9 KII93716.1 - 0.074 13.4 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) NPL4 PF05021.15 KII93717.1 - 3.5e-104 348.5 0.0 5.6e-104 347.8 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KII93717.1 - 6e-63 211.3 0.0 9.8e-63 210.6 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KII93717.1 - 2.1e-05 24.9 0.0 4.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.15 KII93718.1 - 3e-09 36.8 9.9 1.5e-08 34.6 9.9 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 KII93718.1 - 8.3e-05 22.6 4.7 0.00016 21.7 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Zwint PF15556.6 KII93718.1 - 0.098 12.1 2.5 0.17 11.4 2.5 1.4 1 0 0 1 1 1 0 ZW10 interactor CCDC85 PF10226.9 KII93718.1 - 0.37 10.4 10.0 0.017 14.8 4.0 1.7 2 0 0 2 2 2 0 CCDC85 family bZIP_Maf PF03131.17 KII93718.1 - 0.73 10.4 7.2 0.11 13.0 3.1 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Pneumo_att_G PF05539.11 KII93718.1 - 3.6 7.1 7.7 0.49 9.9 2.4 1.9 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G CHCH PF06747.13 KII93719.1 - 1e-05 25.5 2.4 1.6e-05 24.9 2.4 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KII93719.1 - 0.00093 19.2 1.5 0.0014 18.6 1.5 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 KII93719.1 - 0.004 16.8 0.3 0.0055 16.4 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KII93719.1 - 0.0059 16.9 2.5 0.01 16.1 2.5 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GDPD PF03009.17 KII93720.1 - 6.6e-35 121.1 0.0 8.5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KII93720.1 - 1.6e-05 25.2 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.14 KII93721.1 - 2.9e-11 43.7 1.1 1.1e-10 41.9 1.1 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KII93721.1 - 9.2e-11 41.5 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.25 KII93725.1 - 3.9e-41 141.2 0.0 3.6e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII93725.1 - 1.5e-10 40.8 0.0 5e-05 22.7 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII93725.1 - 0.003 16.4 0.0 0.0044 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase MCM PF00493.23 KII93726.1 - 2.9e-102 340.5 0.0 1.1e-101 338.6 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KII93726.1 - 1.3e-34 118.7 0.0 3.5e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KII93726.1 - 1.1e-30 105.9 0.4 3.3e-30 104.3 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KII93726.1 - 1.3e-14 54.6 0.0 3.6e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KII93726.1 - 6.1e-07 29.0 0.0 0.00024 20.6 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KII93726.1 - 8.4e-05 22.6 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KII93726.1 - 0.00043 20.1 0.1 0.0022 17.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KII93726.1 - 0.02 15.5 0.3 0.32 11.7 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KII93726.1 - 0.042 14.3 0.0 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NAP PF00956.18 KII93727.1 - 2.5e-25 89.2 1.0 3.6e-24 85.4 0.4 2.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Polysacc_deac_1 PF01522.21 KII93728.1 - 4.5e-29 100.9 0.0 8.6e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KII93728.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DASH_Dad2 PF08654.10 KII93728.1 - 0.028 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 ADH_N PF08240.12 KII93729.1 - 1.8e-25 89.0 4.7 3.1e-25 88.2 4.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII93729.1 - 8e-19 67.9 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII93729.1 - 0.0022 19.1 0.0 0.0055 17.8 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 KII93729.1 - 0.021 14.5 0.1 0.032 13.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 KII93729.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Pex16 PF08610.10 KII93730.1 - 4.6e-108 361.2 0.4 5.2e-108 361.0 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) APG6_N PF17675.1 KII93731.1 - 0.014 15.9 5.7 0.028 14.9 5.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region HD_3 PF13023.6 KII93731.1 - 0.037 14.0 2.2 0.066 13.1 2.2 1.3 1 0 0 1 1 1 0 HD domain Cep57_CLD_2 PF14197.6 KII93731.1 - 0.038 14.1 5.0 0.12 12.5 5.0 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.8 KII93731.1 - 0.042 13.8 1.7 0.12 12.4 1.7 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1489 PF07370.11 KII93731.1 - 0.047 13.4 0.2 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1489) Sulfatase PF00884.23 KII93731.1 - 0.055 12.9 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Sulfatase YabA PF06156.13 KII93731.1 - 0.34 11.6 1.5 0.87 10.3 1.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KII93731.1 - 0.53 10.8 6.2 1.5 9.4 6.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Uso1_p115_C PF04871.13 KII93731.1 - 1.2 9.6 6.7 2.4 8.6 6.7 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 KII93731.1 - 1.4 9.0 10.1 27 4.8 0.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MCPVI PF02993.14 KII93731.1 - 3.6 7.3 5.9 2.4 7.9 2.3 2.4 3 0 0 3 3 3 0 Minor capsid protein VI ICE2 PF08426.10 KII93732.1 - 2.5e-31 109.2 26.5 4.3e-18 65.6 12.2 2.9 1 1 0 2 2 2 2 ICE2 Peptidase_S10 PF00450.22 KII93733.1 - 1.7e-84 284.7 0.2 2.1e-84 284.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MoaE PF02391.17 KII93734.1 - 4.8e-40 136.3 0.3 5.8e-40 136.1 0.3 1.1 1 0 0 1 1 1 1 MoaE protein Indigoidine_A PF04227.12 KII93735.1 - 1.7e-125 418.2 0.3 3.3e-125 417.3 0.3 1.5 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KII93735.1 - 3e-22 79.3 0.0 1.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ResIII PF04851.15 KII93736.1 - 8.4e-20 71.5 0.0 1.6e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII93736.1 - 4.5e-16 59.2 0.1 2.5e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII93736.1 - 7.3e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KII93736.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KII93736.1 - 0.0024 16.6 0.0 0.0052 15.6 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.6 KII93736.1 - 0.003 17.9 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF1104 PF06518.11 KII93736.1 - 0.12 12.8 1.0 0.32 11.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DEAD_2 PF06733.15 KII93736.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Mito_carr PF00153.27 KII93737.1 - 1.7e-63 210.5 5.5 2.5e-23 81.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PINIT PF14324.6 KII93738.1 - 2.8e-41 141.2 1.4 4.8e-41 140.5 1.4 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KII93738.1 - 3.7e-19 68.2 7.4 6.9e-19 67.3 7.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KII93738.1 - 2.8e-07 30.2 3.0 7.5e-07 28.9 3.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 KII93738.1 - 0.16 11.8 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif SAP PF02037.27 KII93738.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.1 3 0 0 3 3 3 0 SAP domain MRC1 PF09444.10 KII93738.1 - 0.56 10.7 2.2 1.2e+02 3.2 0.4 3.1 3 0 0 3 3 3 0 MRC1-like domain zf-C3HC4_2 PF13923.6 KII93738.1 - 6.5 6.7 6.7 14 5.6 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CS PF04969.16 KII93739.1 - 1.8e-19 70.5 1.0 2.3e-19 70.2 0.5 1.5 2 0 0 2 2 2 1 CS domain DUF4413 PF14372.6 KII93741.1 - 1.5e-05 25.3 0.1 1.9e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Terminase_3 PF04466.13 KII93741.1 - 0.057 12.9 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit Trypan_glycop PF00913.19 KII93741.1 - 0.083 12.1 0.5 0.1 11.8 0.5 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Dimer_Tnp_hAT PF05699.14 KII93742.1 - 6.6e-08 32.2 0.2 8.5e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NUC153 PF08159.12 KII93743.1 - 5.7e-14 51.6 20.6 1.6e-13 50.2 2.2 4.1 4 0 0 4 4 4 3 NUC153 domain Hormone_3 PF00159.18 KII93743.1 - 6.7 6.9 7.5 19 5.5 0.3 2.9 2 0 0 2 2 2 0 Pancreatic hormone peptide DUF1648 PF07853.11 KII93744.1 - 2.5e-09 36.6 0.1 8.7 6.1 0.0 6.4 2 1 5 7 7 7 5 Protein of unknown function (DUF1648) Nmad4 PF18756.1 KII93744.1 - 4.6e-05 23.7 0.0 26 5.2 0.0 4.7 1 1 5 6 6 6 2 Nucleotide modification associated domain 4 RIBIOP_C PF04950.12 KII93744.1 - 0.0025 17.3 0.0 1.2e+02 1.9 0.0 5.3 6 0 0 6 6 6 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Mtd_N PF18454.1 KII93744.1 - 3.9 7.6 5.4 1.8e+02 2.2 0.0 4.1 5 0 0 5 5 5 0 Major tropism determinant N-terminal domain Cupin_2 PF07883.11 KII93745.1 - 3.4e-07 29.9 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 KII93745.1 - 0.052 13.2 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein DUF348 PF03990.14 KII93745.1 - 0.071 12.9 2.6 0.16 11.7 0.5 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain MannoseP_isomer PF01050.18 KII93745.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 Mannose-6-phosphate isomerase adh_short_C2 PF13561.6 KII93746.1 - 7.3e-58 195.9 0.1 8.9e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII93746.1 - 4.7e-45 153.4 0.3 6e-45 153.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII93746.1 - 1.7e-10 41.1 0.1 2.5e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KII93746.1 - 0.081 13.0 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KII93747.1 - 1.7e-48 164.3 0.2 2.5e-48 163.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KII93747.1 - 3e-23 82.7 0.1 7.2e-23 81.5 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KII93747.1 - 7.4e-09 36.1 1.5 1.1e-08 35.6 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KII93747.1 - 2e-05 24.8 0.0 3.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KII93747.1 - 0.00021 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KII93747.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KII93747.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 KII93747.1 - 0.054 13.5 0.1 0.48 10.4 0.1 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Par3_HAL_N_term PF12053.8 KII93748.1 - 0.00023 21.3 2.5 16 5.8 0.0 4.5 2 2 1 4 4 4 1 N-terminal of Par3 and HAL proteins REF PF05755.12 KII93748.1 - 0.034 14.0 19.6 0.25 11.1 6.5 4.7 4 1 1 5 5 5 0 Rubber elongation factor protein (REF) DUF948 PF06103.11 KII93748.1 - 0.096 13.0 6.6 1.2 9.4 0.2 4.1 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1153 PF06627.11 KII93748.1 - 0.35 11.0 5.4 48 4.2 0.0 5.6 5 2 3 8 8 8 0 Protein of unknown function (DUF1153) YppG PF14179.6 KII93748.1 - 0.41 11.4 13.4 11 6.8 0.1 5.5 5 1 2 7 7 7 0 YppG-like protein CorA PF01544.18 KII93749.1 - 3.1e-21 76.0 1.2 2.5e-11 43.4 0.1 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF998 PF06197.13 KII93749.1 - 0.048 13.2 2.9 0.1 12.2 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF998) PIG-U PF06728.13 KII93749.1 - 0.068 12.2 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF3040 PF11239.8 KII93749.1 - 0.11 12.7 0.0 0.61 10.4 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) RRP36 PF06102.12 KII93750.1 - 1.1e-42 145.8 17.7 1.6e-42 145.3 17.7 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 GMC_oxred_N PF00732.19 KII93752.1 - 4.3e-60 203.6 0.0 5.6e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KII93752.1 - 1.3e-32 113.3 0.0 8.7e-32 110.6 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 KII93752.1 - 8.9e-06 25.5 1.0 0.00012 21.8 0.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII93752.1 - 0.00019 20.6 0.2 0.044 12.9 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KII93752.1 - 0.00051 19.2 0.0 0.00071 18.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KII93752.1 - 0.00074 19.7 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KII93752.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KII93752.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII93752.1 - 0.23 10.1 0.0 0.63 8.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_6 PF12697.7 KII93753.1 - 1.1e-16 62.1 1.6 1.4e-16 61.8 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 KII93754.1 - 5.8e-67 226.4 0.0 7.2e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 KII93755.1 - 6.4e-64 216.1 0.1 8.1e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PE-PPE PF08237.11 KII93755.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain BAG6 PF12057.8 KII93756.1 - 0.0096 15.6 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 BCL2-associated athanogene 6 Prenyltransf PF01255.19 KII93756.1 - 0.064 12.8 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase SNAP PF14938.6 KII93757.1 - 4.5e-109 364.2 16.3 5.1e-109 364.1 16.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KII93757.1 - 0.00018 21.3 8.5 0.11 12.6 0.1 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KII93757.1 - 0.0029 18.2 9.6 8.4 7.3 0.1 5.9 4 2 1 6 6 6 1 Tetratricopeptide repeat DUF410 PF04190.13 KII93757.1 - 0.0068 16.2 6.6 0.17 11.7 6.6 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_11 PF13414.6 KII93757.1 - 0.0099 15.5 5.6 2.7 7.7 0.1 5.0 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 KII93757.1 - 0.019 15.1 8.0 2.2 8.7 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII93757.1 - 0.02 15.2 17.2 0.41 11.0 5.5 3.9 2 1 1 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 KII93757.1 - 0.024 13.7 5.5 0.091 11.9 4.1 2.4 2 1 0 2 2 2 0 Spatacsin C-terminus TPR_2 PF07719.17 KII93757.1 - 0.15 12.3 16.6 14 6.1 0.3 6.0 4 1 1 6 6 6 0 Tetratricopeptide repeat DUF3486 PF11985.8 KII93757.1 - 0.59 10.5 3.4 0.34 11.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) PGM_PMM_I PF02878.16 KII93758.1 - 9e-18 64.3 0.1 1.1e-07 31.6 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KII93758.1 - 4.6e-11 42.7 0.6 4.3e-10 39.6 0.5 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KII93758.1 - 0.0054 16.9 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KII93758.1 - 0.033 14.8 0.0 0.45 11.2 0.0 2.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II GATase_4 PF13230.6 KII93759.1 - 1.7e-19 69.8 0.0 3.9e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KII93759.1 - 4.2e-09 36.7 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain RRM_1 PF00076.22 KII93760.1 - 2.9e-41 139.1 0.3 5.4e-21 74.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KII93760.1 - 4.8e-14 53.2 2.4 1.2e-12 48.7 2.4 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 KII93760.1 - 4e-06 26.8 0.6 0.0022 18.0 0.0 2.9 2 1 1 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 KII93760.1 - 0.0014 18.5 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KII93760.1 - 0.0068 16.0 0.0 3.5 7.2 0.0 2.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KII93760.1 - 0.016 15.2 0.1 10 6.2 0.1 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KII93760.1 - 0.11 12.6 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif Zn_clus PF00172.18 KII93761.1 - 2.3e-07 30.8 10.6 4e-07 30.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KII93761.1 - 0.00057 19.0 0.1 0.0011 18.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TB2_DP1_HVA22 PF03134.19 KII93764.1 - 7.1e-23 80.3 6.7 7.1e-23 80.3 6.7 1.6 1 1 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.14 KII93764.1 - 0.0013 19.0 3.2 0.0021 18.3 3.2 1.4 1 0 0 1 1 1 1 GtrA-like protein Sec3_C PF09763.9 KII93765.1 - 7.6e-165 550.2 0.5 1.1e-164 549.7 0.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KII93765.1 - 9.8e-20 70.5 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KII93765.1 - 0.00025 19.9 3.6 0.0022 16.8 3.7 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family DUF4451 PF14616.6 KII93767.1 - 0.0031 17.7 0.2 0.0043 17.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF3912 PF13051.6 KII93767.1 - 0.033 14.4 0.1 0.52 10.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Eapp_C PF10238.9 KII93767.1 - 0.051 13.6 1.1 0.094 12.8 1.1 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein Med3 PF11593.8 KII93767.1 - 0.77 8.9 5.7 1 8.5 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Homeodomain PF00046.29 KII93768.1 - 2e-07 30.7 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain DUF3437 PF11919.8 KII93768.1 - 0.091 12.7 0.0 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Glyco_transf_21 PF13506.6 KII93769.1 - 1.3e-23 83.3 1.3 3.3e-18 65.8 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KII93769.1 - 1.2e-11 45.0 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KII93769.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 TatD_DNase PF01026.21 KII93770.1 - 9.2e-47 159.6 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KII93770.1 - 0.071 12.9 0.0 0.44 10.3 0.0 2.2 2 1 1 3 3 3 0 Amidohydrolase Thiolase_N PF00108.23 KII93771.1 - 9.1e-66 221.9 0.2 1.4e-65 221.2 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KII93771.1 - 1.1e-46 157.5 0.3 2.8e-46 156.2 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KII93771.1 - 5.4e-06 26.2 2.2 0.00046 20.0 0.2 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KII93771.1 - 0.00037 20.2 0.9 0.0014 18.3 0.3 2.2 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KII93771.1 - 0.0037 17.4 0.1 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Hepar_II_III PF07940.13 KII93772.1 - 2.6e-07 30.5 0.5 4.8e-07 29.7 0.5 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein PgaD PF13994.6 KII93773.1 - 0.029 14.4 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 PgaD-like protein Apt1 PF10351.9 KII93773.1 - 1.2 7.9 6.6 1.4 7.7 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain HTH_21 PF13276.6 KII93774.1 - 7.4e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 HTH-like domain Ima1_N PF09779.9 KII93775.1 - 6.8e-35 120.9 0.6 1.1e-34 120.2 0.6 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain SNAPc_SNAP43 PF09808.9 KII93776.1 - 1e-09 38.6 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SKN1 PF03935.15 KII93777.1 - 2.3e-193 643.2 3.0 2.7e-193 643.0 3.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) UQ_con PF00179.26 KII93778.1 - 3.7e-19 68.8 0.0 7.6e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.33 KII93780.1 - 1.1e-06 28.4 0.4 2.3e-06 27.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII93780.1 - 0.0014 18.5 0.8 0.0029 17.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like NAT PF04768.13 KII93781.1 - 3.2e-32 111.5 0.0 1.2e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Fasciclin PF02469.22 KII93784.1 - 1.1e-64 216.4 0.0 2.5e-14 53.6 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 KII93784.1 - 3.1e-62 206.5 3.1 8.4e-21 73.7 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Rav1p_C PF12234.8 KII93785.1 - 7.5e-206 685.4 0.0 1.1e-205 684.8 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal GDI PF00996.18 KII93786.1 - 5.2e-221 733.7 0.1 6e-221 733.5 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor PhnJ PF06007.11 KII93786.1 - 0.052 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ CDC45 PF02724.14 KII93787.1 - 8.2 4.6 11.8 15 3.7 11.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KII93787.1 - 9.4 4.3 14.9 14 3.7 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family Aldedh PF00171.22 KII93788.1 - 9.5e-132 439.8 0.1 1.1e-131 439.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KII93788.1 - 0.03 13.4 0.0 0.064 12.3 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) LMWPc PF01451.21 KII93789.1 - 3.5e-38 131.2 0.0 3.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.15 KII93790.1 - 7.9e-13 48.4 0.0 1.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein YjeJ PF15922.5 KII93790.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 YjeJ-like FANCI_S1-cap PF14674.6 KII93790.1 - 0.21 11.7 0.4 0.55 10.4 0.1 1.9 2 0 0 2 2 2 0 FANCI solenoid 1 cap adh_short PF00106.25 KII93791.1 - 8.5e-44 149.4 0.0 1.3e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII93791.1 - 9.4e-44 149.7 0.0 2.3e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII93791.1 - 6.6e-08 32.7 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Seipin PF06775.14 KII93792.1 - 1.8e-22 80.4 0.0 6.2e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PROL5-SMR PF15621.6 KII93792.1 - 0.028 14.9 0.2 0.1 13.1 0.2 2.0 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF3224 PF11528.8 KII93794.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) LCCL PF03815.19 KII93796.1 - 1.3e-15 57.3 0.1 2.2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF3094 PF11293.8 KII93796.1 - 0.049 13.4 0.3 0.049 13.4 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) Sugar_tr PF00083.24 KII93797.1 - 9e-106 354.4 12.0 1e-105 354.2 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII93797.1 - 2.1e-31 109.2 38.1 1.5e-27 96.4 21.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KII93797.1 - 1e-08 34.2 11.4 7.9e-05 21.4 0.3 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3180 PF11377.8 KII93797.1 - 0.55 10.4 5.7 6.3 7.0 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) PPR_2 PF13041.6 KII93799.1 - 1.6e-50 169.0 0.5 7.6e-10 38.8 0.0 9.3 7 2 2 9 9 9 7 PPR repeat family PPR_3 PF13812.6 KII93799.1 - 1.3e-31 108.4 0.0 3.2e-10 39.9 0.0 5.8 5 1 0 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 KII93799.1 - 1.1e-22 78.7 11.1 0.0013 18.8 0.0 12.4 13 1 0 13 13 13 6 PPR repeat PPR_1 PF12854.7 KII93799.1 - 4.7e-17 61.4 11.1 0.021 14.5 0.0 8.3 8 1 0 8 8 8 5 PPR repeat PPR_long PF17177.4 KII93799.1 - 3.8e-11 42.8 0.0 3.9e-05 23.1 0.0 4.5 3 1 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KII93799.1 - 0.13 12.2 0.0 0.48 10.3 0.0 2.0 1 0 0 1 1 1 0 Mitochondrial ATPase expression Pro_isomerase PF00160.21 KII93800.1 - 4.5e-46 157.0 0.0 6.9e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KII93800.1 - 0.033 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 U-box domain Rtf2 PF04641.12 KII93800.1 - 0.077 12.3 0.0 6.1 6.1 0.0 2.4 3 0 0 3 3 3 0 Rtf2 RING-finger zf-NOSIP PF15906.5 KII93800.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Snf7 PF03357.21 KII93801.1 - 2.7e-33 115.0 7.8 3.2e-33 114.7 7.8 1.0 1 0 0 1 1 1 1 Snf7 SpecificRecomb PF10136.9 KII93801.1 - 0.32 9.3 4.9 0.4 8.9 4.9 1.0 1 0 0 1 1 1 0 Site-specific recombinase Git3 PF11710.8 KII93802.1 - 1.3e-09 38.2 9.0 6.8e-09 35.8 9.0 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3 PF11710.8 KII93803.1 - 0.0023 17.7 3.1 0.0023 17.7 3.1 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KII93803.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.9 4 0 0 4 4 4 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KII93803.1 - 0.4 9.7 7.9 0.44 9.6 6.9 1.5 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor Git3 PF11710.8 KII93804.1 - 1e-07 32.0 13.4 1e-07 32.0 13.4 2.4 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KII93804.1 - 6.1e-06 25.7 5.0 1e-05 25.0 5.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PP2C PF00481.21 KII93805.1 - 2.3e-36 125.7 0.0 6.1e-35 121.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C G_glu_transpept PF01019.21 KII93806.1 - 3.8e-142 474.6 0.0 4.4e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Prefoldin_2 PF01920.20 KII93807.1 - 6.4e-22 77.5 15.3 9e-22 77.0 14.6 1.7 1 1 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 KII93807.1 - 0.0058 16.7 13.3 0.27 11.2 3.7 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 KII93807.1 - 0.0089 14.3 8.2 0.011 14.0 8.2 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ERM PF00769.19 KII93807.1 - 0.0099 15.7 10.4 0.014 15.3 10.4 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6_N PF17675.1 KII93807.1 - 0.019 15.5 16.7 0.15 12.6 5.7 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Tup_N PF08581.10 KII93807.1 - 0.022 15.1 10.9 8.6 6.7 2.8 3.1 1 1 2 3 3 3 0 Tup N-terminal HMMR_N PF15905.5 KII93807.1 - 0.028 13.9 16.2 0.071 12.6 16.2 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 KII93807.1 - 0.031 14.7 7.7 0.84 10.1 2.1 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein betaPIX_CC PF16523.5 KII93807.1 - 0.031 14.1 1.7 0.031 14.1 1.7 2.2 2 1 0 2 2 2 0 betaPIX coiled coil MCU PF04678.13 KII93807.1 - 0.035 14.2 4.3 0.093 12.8 4.3 1.7 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Fib_alpha PF08702.10 KII93807.1 - 0.046 13.9 6.7 0.047 13.9 0.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 KII93807.1 - 0.089 13.1 14.1 0.45 10.8 3.9 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KII93807.1 - 0.092 13.5 6.2 2.3 9.0 0.9 2.2 2 0 0 2 2 2 0 Occludin homology domain DUF4201 PF13870.6 KII93807.1 - 0.11 12.3 9.5 0.3 10.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 KII93807.1 - 0.11 11.3 15.4 0.19 10.6 15.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KII93807.1 - 0.11 12.6 15.5 0.53 10.4 4.4 2.1 2 0 0 2 2 2 0 Tropomyosin like COG2 PF06148.11 KII93807.1 - 0.27 11.3 4.5 1.2 9.2 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LPP PF04728.13 KII93807.1 - 0.43 11.0 7.4 3.2 8.2 2.3 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PHM7_cyt PF14703.6 KII93807.1 - 0.46 10.7 4.8 1.2 9.4 4.8 1.8 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Fez1 PF06818.15 KII93807.1 - 0.65 10.4 14.2 0.17 12.3 4.5 2.1 1 1 1 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 KII93807.1 - 0.68 10.2 11.1 3.5 7.9 1.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 KII93807.1 - 0.94 9.9 9.7 2 8.8 0.6 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin PF02996.17 KII93807.1 - 0.96 9.4 13.3 0.27 11.2 3.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 KII93807.1 - 1.1 9.3 9.3 3 7.9 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KII93807.1 - 1.2 9.3 13.8 3 8.0 3.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1690 PF07956.11 KII93807.1 - 1.3 9.4 10.3 2.2 8.7 10.3 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) TPR_MLP1_2 PF07926.12 KII93807.1 - 1.5 8.9 15.7 1.2 9.2 3.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 KII93807.1 - 1.8 7.7 15.3 0.35 10.0 4.4 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region OmpH PF03938.14 KII93807.1 - 2.8 8.3 21.8 5.4 7.4 4.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.6 KII93807.1 - 2.8 7.2 17.5 2.3e+02 1.0 17.8 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KII93807.1 - 2.9 8.6 12.5 2.1 9.0 3.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA SKA1 PF07160.12 KII93807.1 - 5.1 6.9 12.7 2.3 8.0 3.6 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Rx_N PF18052.1 KII93807.1 - 5.6 7.3 10.8 1.7 9.0 2.9 2.7 1 1 1 2 2 2 0 Rx N-terminal domain YgaB PF14182.6 KII93807.1 - 7.2 7.1 11.2 0.92 9.9 3.4 2.6 2 1 0 2 2 2 0 YgaB-like protein XhlA PF10779.9 KII93807.1 - 9.7 6.5 8.8 1.8 8.8 2.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF724 PF05266.14 KII93807.1 - 9.8 6.0 12.7 11 5.8 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Ribosomal_S17 PF00366.20 KII93809.1 - 1.5e-22 79.4 2.8 2e-22 79.1 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF16 PF01519.16 KII93809.1 - 0.084 13.4 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 MFS_1 PF07690.16 KII93810.1 - 5.9e-43 147.1 42.4 3.5e-42 144.6 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII93810.1 - 4.4e-12 45.6 7.0 4.4e-12 45.6 7.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KII93810.1 - 8.4e-11 41.0 0.5 8.4e-11 41.0 0.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KII93810.1 - 1.4e-07 31.1 2.8 1.4e-07 31.1 2.8 2.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1799 PF08809.11 KII93810.1 - 0.078 13.2 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage related hypothetical protein (DUF1799) ANAPC4_WD40 PF12894.7 KII93811.1 - 8.1e-10 38.9 0.0 0.00014 22.0 0.0 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KII93811.1 - 2.3e-05 25.1 2.4 0.0079 17.0 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.11 KII93811.1 - 0.00041 20.3 0.0 15 5.4 0.0 5.0 5 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Sec39 PF08314.11 KII93812.1 - 3e-104 350.0 0.0 4.1e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 UPF0113_N PF17833.1 KII93814.1 - 7.3e-29 100.2 0.0 1.1e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KII93814.1 - 5.4e-26 90.7 0.0 1.1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain HpuA PF16960.5 KII93814.1 - 0.17 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter NRDE-2 PF08424.10 KII93815.1 - 2.4e-65 220.8 3.4 2.8e-65 220.5 1.3 2.2 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KII93815.1 - 0.00045 20.8 22.5 0.029 15.2 0.0 7.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII93815.1 - 5 7.8 7.8 0.41 11.3 0.4 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UreD PF01774.17 KII93817.1 - 3.1e-66 223.3 0.0 3.8e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein His_Phos_2 PF00328.22 KII93818.1 - 3.1e-43 148.6 0.0 4.3e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 KII93819.1 - 3.4e-25 88.7 60.6 1.4e-23 83.4 37.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M41 PF01434.18 KII93820.1 - 7.3e-62 208.6 0.0 1.9e-61 207.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KII93820.1 - 7.7e-43 146.1 0.0 1.6e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KII93820.1 - 1.5e-13 50.3 0.0 3.4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KII93820.1 - 1.3e-12 48.0 0.0 2.9e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KII93820.1 - 0.0036 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KII93820.1 - 0.0052 17.2 0.1 0.12 12.8 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KII93820.1 - 0.0053 16.8 0.0 0.016 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KII93820.1 - 0.0071 16.5 0.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KII93820.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KII93820.1 - 0.015 15.6 0.1 0.46 10.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KII93820.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 KII93820.1 - 0.082 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain CHAD PF05235.14 KII93820.1 - 0.18 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 CHAD domain LPMO_10 PF03067.15 KII93821.1 - 2e-08 35.2 3.3 3.4e-08 34.4 3.3 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cgr1 PF03879.14 KII93823.1 - 4.2e-31 107.5 29.2 4.8e-31 107.3 29.2 1.0 1 0 0 1 1 1 1 Cgr1 family SGS PF05002.15 KII93823.1 - 0.036 14.2 0.2 0.036 14.2 0.2 2.3 2 1 0 2 2 2 0 SGS domain PBP_sp32 PF07222.12 KII93823.1 - 0.1 12.1 7.3 0.12 11.8 7.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RF-1 PF00472.20 KII93823.1 - 0.14 12.1 13.3 0.23 11.4 13.3 1.6 1 1 0 1 1 1 0 RF-1 domain Macoilin PF09726.9 KII93823.1 - 0.34 9.4 14.1 0.36 9.3 14.1 1.1 1 0 0 1 1 1 0 Macoilin family MCU PF04678.13 KII93823.1 - 0.4 10.7 5.5 0.46 10.6 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PEARLI-4 PF05278.12 KII93823.1 - 0.57 9.7 14.6 0.74 9.4 14.6 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Noc2 PF03715.13 KII93823.1 - 1.3 8.2 4.5 1.7 7.8 4.5 1.1 1 0 0 1 1 1 0 Noc2p family Red1 PF07964.11 KII93823.1 - 2.1 6.5 11.2 2.2 6.4 11.2 1.0 1 0 0 1 1 1 0 Rec10 / Red1 CCDC71L PF15374.6 KII93823.1 - 4.9 6.3 14.1 5.1 6.2 14.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Pep3_Vps18 PF05131.14 KII93824.1 - 4.3e-53 179.1 0.0 8.8e-53 178.1 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KII93824.1 - 2.6e-09 37.1 4.1 5.1e-05 23.2 0.0 3.0 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KII93824.1 - 2.3e-05 24.8 0.0 5.9e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KII93824.1 - 0.0004 20.3 0.9 0.0004 20.3 0.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KII93824.1 - 0.00063 19.5 2.2 0.00063 19.5 2.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII93824.1 - 0.0067 16.4 3.2 0.0097 15.9 1.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII93824.1 - 0.011 16.0 4.3 0.013 15.8 1.2 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 KII93824.1 - 0.012 15.3 4.6 0.012 15.3 4.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KII93824.1 - 0.015 14.9 1.8 0.049 13.2 1.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KII93824.1 - 0.68 9.9 4.8 0.18 11.7 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 KII93824.1 - 0.68 10.2 4.2 8.7 6.7 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 KII93824.1 - 6.8 6.6 5.3 16 5.5 0.0 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 His_Phos_1 PF00300.22 KII93825.1 - 3.7e-39 134.4 0.0 4.7e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TMF_TATA_bd PF12325.8 KII93826.1 - 0.0022 18.2 7.2 0.0022 18.2 7.2 9.7 1 1 7 9 9 9 2 TATA element modulatory factor 1 TATA binding APC_N_CC PF16689.5 KII93826.1 - 0.0046 17.0 1.4 0.0046 17.0 1.4 5.9 7 1 0 7 7 7 1 Coiled-coil N-terminus of APC, dimerisation domain APG6_N PF17675.1 KII93826.1 - 0.0061 17.1 25.0 0.0061 17.1 25.0 7.5 1 1 5 6 6 6 1 Apg6 coiled-coil region DUF2935 PF11155.8 KII93826.1 - 0.037 14.4 0.1 0.037 14.4 0.1 5.0 3 2 1 4 4 4 0 Domain of unknown function (DUF2935) FNIP_M PF14637.6 KII93826.1 - 1.8 8.5 5.0 0.66 9.9 1.7 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain Mito_carr PF00153.27 KII93827.1 - 3.4e-28 97.4 7.0 3.9e-14 52.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WW PF00397.26 KII93830.1 - 0.0067 16.5 3.1 0.014 15.5 3.1 1.6 1 0 0 1 1 1 1 WW domain TRAPPC-Trs85 PF12739.7 KII93831.1 - 1.6e-32 113.0 0.0 2.4e-26 92.6 0.0 2.4 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 KII93831.1 - 0.0025 15.3 0.0 0.0037 14.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Mpv17_PMP22 PF04117.12 KII93832.1 - 1e-11 44.9 3.1 1.6e-11 44.3 3.1 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family YlbE PF14003.6 KII93833.1 - 0.14 12.7 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 YlbE-like protein PWWP PF00855.17 KII93833.1 - 0.58 10.6 3.0 0.4 11.1 0.6 2.0 2 0 0 2 2 2 0 PWWP domain Polyoma_coat2 PF00761.20 KII93835.1 - 5 6.7 5.8 8.3 6.0 5.8 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein Pkinase PF00069.25 KII93837.1 - 7.1e-15 55.1 0.0 1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93837.1 - 0.0059 15.9 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII93839.1 - 2.5e-16 59.9 0.0 3.1e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RS4NT PF08071.12 KII93840.1 - 0.13 12.4 0.5 0.27 11.4 0.5 1.6 1 0 0 1 1 1 0 RS4NT (NUC023) domain Curlin_rpt PF07012.12 KII93843.1 - 0.016 15.2 1.8 0.16 12.0 0.2 2.9 2 0 0 2 2 2 0 Curlin associated repeat Helitron_like_N PF14214.6 KII93844.1 - 1.6e-30 106.8 0.0 3e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4428 PF14471.6 KII93844.1 - 0.08 12.9 0.8 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Ribonuc_red_sm PF00268.21 KII93845.1 - 6.2e-105 350.7 0.1 7.1e-105 350.4 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Clathrin_H_link PF13838.6 KII93848.1 - 0.014 15.3 0.5 0.031 14.2 0.5 1.7 1 0 0 1 1 1 0 Clathrin-H-link LRR_12 PF18837.1 KII93849.1 - 0.088 12.5 1.4 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat Methyltransf_23 PF13489.6 KII93850.1 - 6e-17 62.0 0.0 8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII93850.1 - 2.3e-12 47.4 0.0 4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII93850.1 - 1.7e-10 41.4 0.0 3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII93850.1 - 7.6e-10 38.8 0.0 6.7e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93850.1 - 2.6e-06 28.1 0.0 8e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KII93850.1 - 3.2e-06 26.0 0.0 6.7e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF938 PF06080.12 KII93850.1 - 4.4e-05 23.3 0.0 0.00022 21.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KII93850.1 - 8.7e-05 21.9 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_8 PF05148.15 KII93850.1 - 0.00038 20.4 0.0 0.00069 19.5 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KII93850.1 - 0.0012 18.2 0.0 0.025 13.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KII93850.1 - 0.0047 16.4 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KII93850.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KII93850.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KII93850.1 - 0.016 14.5 0.0 0.097 11.9 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase HMG_box PF00505.19 KII93851.1 - 3.6e-07 30.5 2.2 6.3e-07 29.7 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII93851.1 - 2.3e-05 24.9 1.9 4.1e-05 24.1 1.9 1.4 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.29 KII93853.1 - 5.4e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII93853.1 - 1e-08 35.5 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII93853.1 - 0.00031 20.8 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII93854.1 - 1.8e-14 54.0 0.0 3.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII93854.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 RecQ zinc-binding Spt5_N PF11942.8 KII93854.1 - 0.73 10.9 9.8 0.16 12.9 1.2 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal MFMR_assoc PF16596.5 KII93854.1 - 2.1 8.8 8.7 1.4 9.3 4.6 2.1 2 0 0 2 2 2 0 Disordered region downstream of MFMR FAM176 PF14851.6 KII93854.1 - 4.7 6.9 6.3 9.3 5.9 0.1 2.2 2 0 0 2 2 2 0 FAM176 family NAM-associated PF14303.6 KII93854.1 - 7.8 7.2 10.1 3.3 8.4 4.9 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 KII93854.1 - 10 5.8 8.1 1.8 8.2 2.7 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF4203 PF13886.6 KII93856.1 - 2.3e-51 174.3 31.1 2.3e-51 174.3 31.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) LCD1 PF09798.9 KII93856.1 - 0.014 14.0 0.0 0.031 12.8 0.0 1.7 1 1 0 1 1 1 0 DNA damage checkpoint protein Mucin PF01456.17 KII93856.1 - 5.6 6.9 20.3 0.24 11.4 14.4 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein LAG1-DNAbind PF09271.11 KII93857.1 - 6.3e-27 95.1 0.0 4.5e-24 85.8 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KII93857.1 - 1.8e-22 80.2 0.0 3.9e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.21 KII93858.1 - 3.3e-162 539.2 0.5 4.1e-162 538.9 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KII93858.1 - 2.7e-36 124.3 0.0 6.8e-36 123.1 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KII93858.1 - 0.0001 21.5 0.4 0.00024 20.3 0.4 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KII93858.1 - 0.0051 15.9 0.0 0.04 12.9 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Gly_transf_sug PF04488.15 KII93859.1 - 1.7e-05 25.4 0.0 3.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KII93859.1 - 0.042 13.2 0.2 0.073 12.4 0.2 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KII93860.1 - 4.9e-05 23.9 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KII93860.1 - 0.048 13.0 0.2 0.078 12.3 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TAF1D PF15333.6 KII93860.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Ribul_P_3_epim PF00834.19 KII93861.1 - 2.7e-60 203.2 0.0 3.2e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family 2-Hacid_dh_C PF02826.19 KII93863.1 - 3.6e-54 182.8 0.0 6.4e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII93863.1 - 4.9e-09 36.0 0.0 6.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII93863.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KII93863.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RPN2_C PF18004.1 KII93864.1 - 1.6e-44 151.7 4.6 8.9e-43 146.0 4.1 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KII93864.1 - 9.2e-35 117.3 24.7 3.1e-08 33.6 0.0 8.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KII93864.1 - 1e-18 67.5 0.3 1.2e-14 54.4 0.0 4.3 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KII93864.1 - 7.6e-05 22.6 0.5 3 8.3 0.1 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 KII93864.1 - 0.0011 19.5 2.8 1.3 9.6 0.0 5.0 4 1 2 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.20 KII93864.1 - 0.15 10.6 0.0 0.29 9.7 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_PBS PF03130.16 KII93864.1 - 0.93 10.4 3.3 2.1e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat COX6A PF02046.15 KII93865.1 - 3.7e-28 98.2 0.1 4.4e-28 98.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arm PF00514.23 KII93866.1 - 4.4e-93 302.8 14.9 4.7e-13 48.7 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KII93866.1 - 1.1e-24 86.6 1.3 2.2e-24 85.7 1.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KII93866.1 - 5.9e-22 77.7 2.3 1.1e-07 32.2 0.0 5.6 4 2 2 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 KII93866.1 - 3e-21 74.7 0.4 6.5e-21 73.6 0.4 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KII93866.1 - 1.2e-16 60.9 0.2 3.5e-05 24.1 0.0 5.2 1 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 KII93866.1 - 1.1e-15 56.3 0.4 5.4e-05 23.1 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat Adaptin_N PF01602.20 KII93866.1 - 6.4e-06 25.0 0.0 0.00047 18.9 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 KII93866.1 - 1.3e-05 25.4 1.0 0.02 15.1 0.0 4.2 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 KII93866.1 - 2.3e-05 24.0 0.0 0.11 11.9 0.0 4.0 2 1 1 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 KII93866.1 - 0.00042 20.4 0.3 1.3 9.2 0.0 3.9 3 3 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 KII93866.1 - 0.00055 20.4 0.7 0.69 10.8 0.1 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KII93866.1 - 0.0022 17.4 0.0 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 Mo25-like V-ATPase_H_N PF03224.14 KII93866.1 - 0.12 11.7 0.0 5.7 6.1 0.0 2.9 1 1 0 2 2 2 0 V-ATPase subunit H LSM PF01423.22 KII93867.1 - 1.1e-21 76.2 0.1 1.3e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII93867.1 - 0.028 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KII93867.1 - 0.069 13.3 0.0 0.078 13.1 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Homeodomain PF00046.29 KII93869.1 - 1.3e-08 34.5 0.1 2.4e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Ribosomal_S16 PF00886.19 KII93870.1 - 9.5e-23 80.0 0.0 1.5e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 ACBP PF00887.19 KII93871.1 - 6.6e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 KII93871.1 - 1.4e-12 47.5 0.3 3.1e-12 46.5 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KII93871.1 - 5.3e-10 39.3 2.5 8.8e-08 32.3 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KII93871.1 - 1.1e-09 38.8 0.2 3.8e-09 37.0 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII93871.1 - 1.5e-09 38.2 0.5 7.4e-05 23.2 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII93871.1 - 4.8e-06 26.5 0.4 3.8e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat CoA_binding PF02629.19 KII93872.1 - 4.4e-29 101.0 0.2 4.4e-29 101.0 0.2 1.7 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KII93872.1 - 2.3e-24 85.9 0.1 3.6e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KII93872.1 - 5.8e-09 35.9 0.0 1.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KII93872.1 - 6.6e-05 23.4 0.2 0.00027 21.4 0.0 2.1 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KII93872.1 - 0.12 13.2 0.0 0.57 11.0 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Xpo1 PF08389.12 KII93873.1 - 2.1e-22 79.8 0.0 5.6e-21 75.2 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 KII93873.1 - 7.8e-08 32.1 0.0 1.7e-06 27.9 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain PUL PF08324.11 KII93873.1 - 0.0067 15.7 0.0 0.087 12.0 0.0 2.3 2 0 0 2 2 2 1 PUL domain Croc_4 PF17691.1 KII93873.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 Cnd1 PF12717.7 KII93873.1 - 0.038 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 WVELL PF14043.6 KII93873.1 - 0.046 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 WVELL protein HEAT PF02985.22 KII93873.1 - 0.069 13.4 0.1 5 7.7 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Septin PF00735.18 KII93874.1 - 3.3e-120 400.6 0.1 3.3e-120 400.6 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KII93874.1 - 1.4e-07 31.6 0.8 2.7e-07 30.6 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII93874.1 - 5.7e-06 26.0 1.9 0.00048 19.7 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII93874.1 - 7.6e-05 22.7 0.3 7.6e-05 22.7 0.3 3.0 3 1 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 KII93874.1 - 0.00013 22.3 0.1 0.0017 18.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 KII93874.1 - 0.00083 18.7 0.7 0.0018 17.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 KII93874.1 - 0.002 18.7 5.4 0.017 15.6 0.6 2.6 2 1 0 2 2 2 1 ABC transporter Ras PF00071.22 KII93874.1 - 0.002 17.7 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 KII93874.1 - 0.0082 16.5 0.0 0.029 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KII93874.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KII93874.1 - 0.012 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KII93874.1 - 0.062 13.3 5.3 2.6 8.1 0.1 3.2 2 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KII93874.1 - 0.4 10.4 5.4 2.1 8.0 0.1 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 KII93874.1 - 0.44 9.6 5.2 0.68 9.0 5.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 KII93874.1 - 0.59 9.1 5.0 8 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Exonuc_VII_L PF02601.15 KII93874.1 - 0.61 9.6 3.5 0.3 10.6 1.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KII93874.1 - 5.1 7.5 14.6 4.2e+02 1.3 14.6 2.4 1 1 0 1 1 1 0 AAA domain CN_hydrolase PF00795.22 KII93875.1 - 3.7e-53 180.5 0.0 4.2e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.9 KII93876.1 - 1.7e-31 109.2 0.0 3.5e-31 108.2 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF2606 PF10794.9 KII93876.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF866 PF05907.13 KII93877.1 - 1.2e-56 190.9 0.0 1.3e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Phostensin_N PF13916.6 KII93878.1 - 0.026 14.8 0.3 0.054 13.9 0.3 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Herpes_UL36 PF03586.13 KII93878.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Pertussis_S2S3 PF02918.15 KII93878.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Pkinase PF00069.25 KII93880.1 - 1.8e-66 224.2 0.0 2.5e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93880.1 - 6.6e-44 150.1 0.0 1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII93880.1 - 1.9e-08 34.0 0.0 1.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.6 KII93880.1 - 3.3e-07 30.6 0.0 6.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kdo PF06293.14 KII93880.1 - 0.005 16.2 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KII93880.1 - 0.025 13.4 2.1 0.046 12.5 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 KII93880.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MGTL PF17059.5 KII93880.1 - 5.9 6.9 14.7 0.18 11.6 4.8 3.6 2 0 0 2 2 2 0 MgtA leader peptide CLTH PF10607.9 KII93881.1 - 4.5e-33 114.2 0.0 5.4e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KII93881.1 - 6.3e-06 26.0 0.2 1.4e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 LisH FPRL1_inhibitor PF16104.5 KII93881.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.5 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein FMO-like PF00743.19 KII93882.1 - 5.3e-32 110.9 0.0 1.4e-22 79.9 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KII93882.1 - 3.5e-09 36.3 0.2 5.8e-06 25.8 0.0 4.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII93882.1 - 5.5e-08 32.4 0.0 6.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII93882.1 - 1.6e-07 30.8 0.5 1.9e-05 24.0 0.1 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KII93882.1 - 2.1e-07 31.1 0.2 0.0003 20.8 0.0 3.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KII93882.1 - 1.3e-05 24.5 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KII93882.1 - 6e-05 23.2 0.0 0.02 15.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF498 PF04430.14 KII93882.1 - 0.032 14.3 0.1 14 5.8 0.0 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) HI0933_like PF03486.14 KII93882.1 - 0.22 10.2 0.1 2.5 6.7 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KII93882.1 - 1.5 7.9 2.2 1.7 7.6 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Rrp15p PF07890.12 KII93883.1 - 1.2e-28 100.0 7.8 3.4e-28 98.6 7.8 1.8 1 1 0 1 1 1 1 Rrp15p DNA_pol_phi PF04931.13 KII93883.1 - 0.57 8.2 6.3 0.78 7.8 6.3 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KII93883.1 - 0.72 8.1 6.6 1 7.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 KII93883.1 - 2.4 8.0 8.2 10 6.0 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DIL PF01843.19 KII93884.1 - 5.9e-28 97.2 0.8 1.9e-27 95.6 0.2 2.0 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 KII93884.1 - 5.3e-12 46.2 0.0 5.9e-06 26.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII93884.1 - 4.8e-10 39.8 0.1 3.1e-07 30.8 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KII93884.1 - 4.3e-08 33.2 0.4 0.0045 17.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KII93884.1 - 1.5e-07 31.5 0.2 6.9e-05 23.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII93884.1 - 2.4e-07 30.5 0.3 0.0014 19.0 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat DUF4611 PF15387.6 KII93884.1 - 4.7 7.5 6.3 16 5.8 0.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) SnoaL PF07366.12 KII93885.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KII93885.1 - 4e-05 24.2 0.1 7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Rhomboid PF01694.22 KII93886.1 - 2.7e-31 108.6 10.9 2.7e-31 108.6 10.9 1.7 2 0 0 2 2 2 1 Rhomboid family DUF3094 PF11293.8 KII93886.1 - 0.018 14.7 0.6 3.9 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Cas1_AcylT PF07779.12 KII93887.1 - 3.9e-133 444.9 12.9 6.1e-133 444.2 12.9 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KII93887.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short_C2 PF13561.6 KII93888.1 - 1.8e-55 188.0 5.7 2.2e-55 187.8 5.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII93888.1 - 2.9e-41 141.1 2.4 3.8e-41 140.7 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII93888.1 - 9.2e-11 42.0 0.3 1.6e-10 41.2 0.3 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KII93888.1 - 0.04 14.5 0.1 0.11 13.1 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KII93888.1 - 0.042 13.7 0.2 0.074 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OCC1 PF15506.6 KII93888.1 - 0.12 12.5 2.2 0.58 10.3 1.2 2.4 2 0 0 2 2 2 0 OCC1 family Cut8 PF08559.10 KII93889.1 - 3.5e-12 46.4 0.2 3.1e-11 43.3 0.0 2.5 1 1 1 2 2 2 1 Cut8, nuclear proteasome tether protein EF-hand_13 PF17958.1 KII93889.1 - 0.076 12.8 0.1 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain Methyltransf_23 PF13489.6 KII93890.1 - 3.9e-09 36.6 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII93890.1 - 8e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII93890.1 - 8.2e-07 29.6 0.0 2.6e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93890.1 - 1.6e-05 25.6 0.0 3.8e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII93890.1 - 7.8e-05 22.5 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KII93890.1 - 0.067 12.2 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PPR_2 PF13041.6 KII93891.1 - 0.0072 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family RNase_T PF00929.24 KII93892.1 - 3e-05 24.6 0.0 4.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF3025 PF11227.8 KII93892.1 - 0.027 14.3 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) Mito_carr PF00153.27 KII93893.1 - 1.8e-49 165.6 3.8 1.8e-16 59.8 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2793 PF10983.8 KII93893.1 - 0.0072 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2793) RINGv PF12906.7 KII93894.1 - 5.8e-14 51.9 4.5 8.9e-14 51.4 4.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KII93894.1 - 0.00014 22.2 6.6 0.00022 21.5 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain EI24 PF07264.11 KII93894.1 - 0.015 15.5 0.9 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) EptA_B_N PF08019.12 KII93894.1 - 0.071 13.0 1.7 0.88 9.4 0.1 2.2 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB zf-C3HC4 PF00097.25 KII93894.1 - 0.15 12.0 2.6 0.59 10.1 2.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KII93894.1 - 0.33 10.8 5.4 0.6 10.0 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KII93894.1 - 0.46 10.4 4.5 0.72 9.8 4.5 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KII93894.1 - 0.6 10.0 5.7 1.3 8.9 5.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nucleoporin_N PF08801.11 KII93895.1 - 2.5e-66 224.2 0.1 4.3e-66 223.5 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KII93895.1 - 9.1e-31 107.3 0.0 1.6e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Gram_pos_anchor PF00746.21 KII93896.1 - 6.7 6.8 6.8 23 5.1 6.8 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif NAD_binding_6 PF08030.12 KII93897.1 - 1.5e-23 83.6 0.0 2.9e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KII93897.1 - 1.2e-20 73.6 0.0 2.5e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KII93897.1 - 1.7e-18 66.9 12.3 3.1e-18 66.1 12.3 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KII93897.1 - 0.0012 19.5 0.0 0.031 14.9 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain TMEM43 PF07787.12 KII93897.1 - 0.097 12.0 0.4 0.18 11.1 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 FAD_binding_6 PF00970.24 KII93897.1 - 0.099 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ntox3 PF15536.6 KII93897.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 3 HORMA PF02301.18 KII93898.1 - 2.8e-14 53.2 0.2 5.9e-14 52.2 0.2 1.5 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KII93898.1 - 0.002 18.1 0.2 0.012 15.6 0.2 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 Proton_antipo_M PF00361.20 KII93898.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Proton-conducting membrane transporter Acetyltransf_1 PF00583.25 KII93899.1 - 2.4e-10 40.7 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII93899.1 - 1.1e-07 32.1 0.1 3.7e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII93899.1 - 2.5e-06 28.2 0.0 3.5e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII93899.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KII93899.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KII93899.1 - 0.0082 16.3 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KII93899.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Meth_synt_2 PF01717.18 KII93901.1 - 1.8e-13 50.5 0.0 5.3e-12 45.7 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KII93901.1 - 0.007 15.9 0.0 0.037 13.5 0.0 2.2 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 KII93902.1 - 2.1e-76 255.8 7.8 3e-76 255.3 7.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Pal1 PF08316.11 KII93903.1 - 5.2e-15 56.4 0.3 5.2e-15 56.4 0.3 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein FA_desaturase PF00487.24 KII93904.1 - 1.2e-26 94.1 22.5 1.8e-26 93.6 22.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KII93904.1 - 1.9e-07 31.2 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HhH-GPD PF00730.25 KII93905.1 - 1.7e-22 79.9 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KII93905.1 - 3.9e-07 29.6 0.0 9.4e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KII93905.1 - 0.008 16.8 0.5 1 10.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain His_biosynth PF00977.21 KII93906.1 - 3.3e-43 147.8 0.5 1.7e-42 145.4 0.5 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KII93906.1 - 4e-17 62.6 0.0 6.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KII93906.1 - 2.1e-07 31.0 0.0 2.7e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KII93906.1 - 2.5e-07 30.5 0.0 5.4e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KII93906.1 - 0.022 14.5 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 ThiG PF05690.14 KII93906.1 - 0.076 12.3 0.4 0.12 11.6 0.4 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.17 KII93906.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 2-Hacid_dh_C PF02826.19 KII93907.1 - 1.5e-51 174.3 0.0 4.1e-51 172.9 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII93907.1 - 1.1e-33 115.7 0.0 1.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII93907.1 - 0.0096 16.1 0.0 0.034 14.3 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KII93907.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2597 PF10772.9 KII93907.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) UPF0515 PF15135.6 KII93908.1 - 0.19 11.1 1.0 0.25 10.7 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Hydrolase_4 PF12146.8 KII93909.1 - 2.8e-13 49.7 0.0 1e-08 34.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII93909.1 - 3.6e-12 46.5 0.1 4.4e-08 33.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KII93909.1 - 6.4e-08 32.8 0.3 0.00017 21.6 0.1 2.4 3 0 0 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KII93909.1 - 2.2e-07 31.7 0.1 6.1e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII93909.1 - 3.9e-07 29.8 0.0 1.1e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KII93909.1 - 6.8e-06 26.0 0.1 0.055 13.3 0.1 3.1 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 KII93909.1 - 3.4e-05 22.7 0.0 0.027 13.1 0.0 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 KII93909.1 - 0.00012 21.7 0.0 0.0018 17.9 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KII93909.1 - 0.0004 20.1 0.0 0.74 9.4 0.0 2.4 2 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KII93909.1 - 0.00064 19.5 0.0 0.019 14.7 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.13 KII93909.1 - 0.0028 17.3 0.0 0.0063 16.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 KII93909.1 - 0.0071 16.0 0.1 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 Putative esterase DUF1100 PF06500.11 KII93909.1 - 0.065 12.0 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF818 PF05677.12 KII93909.1 - 0.095 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.12 KII93909.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 KII93909.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Transp_cyt_pur PF02133.15 KII93910.1 - 2.4e-82 277.1 32.2 2.9e-82 276.8 32.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 KII93911.1 - 4.1e-27 95.3 0.1 7.7e-27 94.4 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII93911.1 - 2.1e-16 60.3 0.0 3.4e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.21 KII93912.1 - 4e-21 75.6 0.0 5.2e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF917 PF06032.12 KII93913.1 - 1.2e-117 392.7 0.1 2.6e-117 391.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KII93913.1 - 8.6e-27 94.0 0.8 4e-26 91.8 0.1 2.5 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KII93913.1 - 1e-22 80.7 5.8 3.5e-22 79.0 1.0 3.1 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase MutL PF13941.6 KII93913.1 - 1e-05 24.3 1.6 0.0014 17.3 0.1 2.6 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 KII93913.1 - 0.0005 19.6 0.1 0.013 15.0 0.0 2.7 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Aldo_ket_red PF00248.21 KII93914.1 - 1.7e-44 152.2 0.0 4.2e-44 150.9 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.29 KII93915.1 - 1.2e-15 57.7 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII93915.1 - 5.3e-15 55.7 0.0 2.2e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KII93915.1 - 8.2e-07 29.7 0.1 1.9e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Ferritin PF00210.24 KII93915.1 - 0.098 12.6 0.2 0.72 9.8 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain DUF5423 PF17461.2 KII93916.1 - 0.068 12.0 0.1 0.075 11.9 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) WD40 PF00400.32 KII93918.1 - 7e-46 153.3 12.4 1e-08 35.7 0.7 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KII93918.1 - 5.1e-30 104.4 0.0 9.5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KII93918.1 - 5.6e-11 42.6 0.1 0.0027 18.0 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KII93918.1 - 0.00016 21.5 0.5 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 LisH Nup160 PF11715.8 KII93918.1 - 0.003 16.3 0.8 5.3 5.6 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KII93918.1 - 0.029 14.2 0.0 0.76 9.6 0.0 2.4 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KII93918.1 - 0.19 11.0 0.0 14 4.9 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain CRAL_TRIO PF00650.20 KII93920.1 - 2.4e-30 105.4 0.0 3.1e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII93920.1 - 5.6e-08 32.8 0.1 1.2e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TFIIF_beta PF02270.15 KII93920.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Ribosomal_L4 PF00573.22 KII93921.1 - 1.8e-55 187.6 1.5 2.1e-55 187.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 KII93922.1 - 1.2e-31 109.8 0.3 1.3e-31 109.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Tim17 PF02466.19 KII93925.1 - 1.1e-06 29.0 8.6 2.1e-06 28.1 8.6 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KII93926.1 - 2.2e-10 41.0 4.9 0.00069 20.4 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat SUR7 PF06687.12 KII93928.1 - 1.9e-19 70.1 10.8 1.9e-19 70.1 10.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF5336 PF17270.2 KII93928.1 - 0.25 11.0 3.7 1.5 8.4 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DUF5090 PF17009.5 KII93928.1 - 4.8 7.1 7.1 0.39 10.6 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) ORC6 PF05460.13 KII93929.1 - 7 5.8 11.7 8.2 5.6 11.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Glyco_transf_28 PF03033.20 KII93930.1 - 2.1e-29 102.3 0.0 4.1e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KII93930.1 - 2.7e-23 82.0 0.5 4.9e-14 52.2 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KII93930.1 - 1.6e-12 47.9 0.2 1.3e-11 44.9 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KII93930.1 - 9.9e-05 22.6 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 KII93930.1 - 0.00019 20.4 0.0 0.00045 19.1 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 KII93930.1 - 0.00028 21.3 0.7 0.04 14.3 0.7 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KII93930.1 - 0.0046 17.2 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DIOX_N PF14226.6 KII93931.1 - 0.00013 22.7 0.0 0.00025 21.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII93931.1 - 0.0049 17.3 0.0 0.013 16.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 KII93933.1 - 1.9e-23 83.5 0.0 5.4e-23 81.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII93933.1 - 2.6e-13 51.1 0.1 3.4e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII93933.1 - 5.4e-09 35.7 0.0 8.7e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KII93933.1 - 0.0033 17.0 0.0 0.0077 15.9 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 KII93933.1 - 0.032 14.3 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain UPF0261 PF06792.11 KII93934.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DUF2431 PF10354.9 KII93935.1 - 3.9e-54 183.4 0.0 8.3e-54 182.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) RAMP4 PF06624.12 KII93936.1 - 1.4e-16 60.3 0.1 1.8e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 CAF1C_H4-bd PF12265.8 KII93937.1 - 1.7e-29 101.9 1.0 4.8e-29 100.4 0.6 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KII93937.1 - 4e-17 62.3 10.7 6.2e-06 26.9 0.5 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII93937.1 - 0.00086 19.6 0.0 0.009 16.3 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KII93937.1 - 0.019 13.3 0.0 0.029 12.7 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ATP-synt_E PF05680.12 KII93938.1 - 1.1e-17 64.1 0.1 1.3e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain GFA PF04828.14 KII93939.1 - 2e-07 31.3 0.6 3e-07 30.7 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CIAPIN1 PF05093.13 KII93939.1 - 0.048 14.2 1.8 0.79 10.3 0.0 2.2 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PTPRCAP PF15713.5 KII93941.1 - 0.77 10.0 6.1 1.6 9.0 6.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 KII93941.1 - 6 5.0 6.8 7.6 4.7 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Dopey_N PF04118.14 KII93942.1 - 4e-111 371.0 1.5 4e-110 367.7 0.0 2.7 3 0 0 3 3 3 2 Dopey, N-terminal EF-hand_6 PF13405.6 KII93943.1 - 5.2e-11 41.5 0.2 4.5e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KII93943.1 - 4.8e-08 32.2 0.1 5.6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KII93943.1 - 1.6e-07 31.7 1.2 4e-07 30.4 1.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KII93943.1 - 2.6e-06 26.6 0.3 0.00076 18.9 0.0 2.5 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 KII93943.1 - 0.016 15.5 0.7 1.5 9.2 0.7 2.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KII93943.1 - 0.017 15.0 0.1 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair ABC2_membrane PF01061.24 KII93944.1 - 1.8e-68 230.1 49.0 4e-37 127.7 16.8 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KII93944.1 - 1.3e-32 113.1 0.0 8.2e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KII93944.1 - 4.5e-24 84.2 0.7 1.2e-17 63.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KII93944.1 - 4.6e-10 40.0 0.0 1.5e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 KII93944.1 - 3.4e-06 27.6 0.0 0.0043 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII93944.1 - 4.7e-05 23.7 0.3 0.5 10.6 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KII93944.1 - 6e-05 23.2 0.0 0.14 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII93944.1 - 0.00014 21.5 0.1 0.13 12.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain cobW PF02492.19 KII93944.1 - 0.00019 21.1 0.0 0.31 10.6 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KII93944.1 - 0.00038 20.9 0.1 0.058 13.8 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KII93944.1 - 0.00093 19.5 0.0 0.18 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII93944.1 - 0.0028 17.3 0.1 0.061 12.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KII93944.1 - 0.0054 16.7 0.0 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 KII93944.1 - 0.0074 16.7 0.0 1.8 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII93944.1 - 0.012 15.3 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KII93944.1 - 0.02 14.7 0.1 4.1 7.1 0.0 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dpoe2NT PF12213.8 KII93944.1 - 0.05 13.9 0.2 0.54 10.6 0.0 2.4 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal SMC_N PF02463.19 KII93944.1 - 0.13 11.6 2.7 1.8 8.0 0.0 3.6 4 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KII93944.1 - 0.2 11.7 0.1 8.6 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 KII93944.1 - 0.3 11.4 0.7 13 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.20 KII93945.1 - 2e-14 53.4 6.6 2.4e-14 53.2 6.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 KII93945.1 - 0.012 15.5 2.0 0.015 15.1 2.0 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein FAM91_C PF14648.6 KII93945.1 - 0.032 13.1 1.4 0.037 12.9 1.4 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Csm1_B PF18211.1 KII93945.1 - 0.089 12.6 0.2 0.19 11.6 0.1 1.7 2 1 0 2 2 2 0 Csm1 subunit domain B CorA PF01544.18 KII93945.1 - 0.4 10.0 4.6 3.6 6.8 0.6 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Coat_F PF07875.12 KII93945.1 - 1.2 9.4 5.1 1.7 9.0 0.1 2.5 3 0 0 3 3 3 0 Coat F domain DivIC PF04977.15 KII93945.1 - 3 7.7 9.5 0.26 11.1 3.0 2.1 2 0 0 2 2 2 0 Septum formation initiator Calreticulin PF00262.18 KII93946.1 - 2.2e-158 526.9 8.1 3.1e-158 526.5 8.1 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 KII93946.1 - 1.5e-45 155.2 0.0 2.2e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KII93946.1 - 7.5e-37 126.6 3.9 7.5e-37 126.6 3.9 2.1 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KII93946.1 - 6.4e-23 80.8 0.0 1.5e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KII93946.1 - 7.4e-22 77.2 0.0 1.7e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KII93946.1 - 8.1e-09 35.8 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KII93946.1 - 1.1e-05 25.5 0.0 4.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KII93946.1 - 1.6e-05 24.9 0.1 3.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KII93946.1 - 0.003 17.0 0.1 0.0066 15.9 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KII93946.1 - 0.082 13.0 0.3 25 4.9 0.1 2.9 2 1 1 3 3 3 0 Dynamin family polyprenyl_synt PF00348.17 KII93947.1 - 4.3e-63 212.8 0.0 3e-58 196.9 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase DUF5632 PF18646.1 KII93949.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5632) Pkinase PF00069.25 KII93950.1 - 9.6e-26 90.7 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93950.1 - 1.9e-13 50.3 0.0 2.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII93950.1 - 5.9e-09 35.2 0.1 8e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII93950.1 - 0.0022 18.0 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KII93950.1 - 0.067 12.1 0.1 0.098 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.20 KII93952.1 - 3.2e-116 389.0 0.0 4.2e-116 388.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KII93952.1 - 1e-57 194.5 1.3 2.4e-57 193.3 1.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KII93952.1 - 1.2e-34 118.9 0.0 2.7e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KII93952.1 - 2e-17 63.3 0.2 5.7e-09 36.3 0.0 6.2 2 2 5 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KII93952.1 - 2.1e-06 27.9 6.3 0.054 13.5 0.1 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KII93952.1 - 0.1 12.9 7.2 16 6.1 0.2 6.2 7 0 0 7 7 7 0 HEAT repeat DUF3385 PF11865.8 KII93952.1 - 0.12 12.3 0.4 3 7.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) Fumble PF03630.14 KII93953.1 - 1e-130 435.8 0.0 1.7e-130 435.1 0.0 1.3 1 1 0 1 1 1 1 Fumble Homeodomain PF00046.29 KII93954.1 - 1.3e-43 146.6 10.9 3.7e-16 58.7 0.4 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KII93954.1 - 9.3e-17 60.7 3.4 3.9e-06 26.7 0.2 3.8 3 0 0 3 3 3 3 Homeobox KN domain HOCHOB PF17943.1 KII93954.1 - 1.4e-08 35.4 0.0 0.048 14.4 0.0 3.2 3 0 0 3 3 3 3 Homeobox-cysteine loop-homeobox YdaS_antitoxin PF15943.5 KII93954.1 - 0.00019 21.2 0.1 0.21 11.4 0.0 3.2 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 KII93954.1 - 0.00083 19.4 0.8 0.9 9.7 0.1 3.0 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.8 KII93954.1 - 0.027 13.9 0.3 19 4.8 0.0 3.4 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez PhzC-PhzF PF02567.16 KII93955.1 - 7.4e-42 143.7 0.2 9.9e-42 143.3 0.2 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Metallophos PF00149.28 KII93956.1 - 4.8e-09 37.0 1.8 1.7e-08 35.2 1.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KII93956.1 - 0.049 13.8 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 KII93957.1 - 3.1e-28 98.9 0.0 3.7e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93957.1 - 2.3e-15 56.6 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII93957.1 - 7.4e-10 38.2 0.1 9.3e-10 37.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII93957.1 - 0.00034 20.6 0.1 0.0061 16.5 0.1 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KII93957.1 - 0.026 13.5 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Chitin_synth_1 PF01644.17 KII93958.1 - 9.4e-72 240.3 0.3 1.5e-71 239.7 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KII93958.1 - 2.6e-27 94.6 0.1 6.9e-27 93.2 0.1 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KII93958.1 - 1e-22 80.5 0.2 1.3e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KII93958.1 - 2e-06 27.8 0.2 2e-06 27.8 0.2 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KII93958.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 cNMP_binding PF00027.29 KII93959.1 - 8.3e-28 96.3 0.0 4.8e-15 55.4 0.0 4.9 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KII93959.1 - 1.4e-18 67.8 3.4 7e-12 45.9 1.3 2.8 2 0 0 2 2 2 2 Patatin-like phospholipase YABBY PF04690.13 KII93960.1 - 4.3e-10 40.4 2.0 5e-10 40.2 2.0 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 KII93960.1 - 0.00013 22.6 4.5 0.00015 22.3 4.5 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 KII93960.1 - 0.00032 21.1 3.5 0.00044 20.6 3.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII93960.1 - 0.00048 20.7 3.0 0.00068 20.2 3.0 1.4 1 1 0 1 1 1 1 HMG-box domain LRR_4 PF12799.7 KII93961.1 - 5.3e-06 26.7 8.3 0.36 11.3 0.2 6.1 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII93961.1 - 0.00011 22.1 0.0 0.00027 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 KII93961.1 - 0.55 11.0 10.8 7.7 7.5 0.2 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KII93961.1 - 2 8.7 16.2 12 6.3 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat Sas10_Utp3 PF04000.15 KII93962.1 - 1.6e-15 57.5 0.1 1.6e-15 57.5 0.1 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Phage_cap_E PF03864.15 KII93962.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.5 2 0 0 2 2 2 0 Phage major capsid protein E SF3b10 PF07189.11 KII93963.1 - 6.3e-35 119.1 0.0 7.7e-35 118.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_25 PF13649.6 KII93964.1 - 1.6e-14 54.3 0.0 3.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII93964.1 - 1.7e-13 51.0 0.0 1.7e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII93964.1 - 9.7e-10 38.5 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII93964.1 - 4.7e-08 33.7 0.0 1.7e-07 31.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII93964.1 - 4.6e-06 26.5 0.0 8.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII93964.1 - 1.3e-05 24.7 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KII93964.1 - 0.0047 17.1 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 KII93964.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB WLM PF08325.10 KII93965.1 - 4.6e-56 189.9 0.0 6.1e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KII93965.1 - 6.6e-06 25.3 11.2 2.3e-05 23.6 0.9 3.2 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others SVIP PF15811.5 KII93965.1 - 0.00054 20.4 6.8 0.094 13.2 0.1 2.8 3 0 0 3 3 3 2 Small VCP/p97-interacting protein DUF45 PF01863.17 KII93965.1 - 0.0046 17.0 0.1 0.0086 16.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.7 KII93965.1 - 0.11 12.5 7.8 0.21 11.7 7.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-UBP PF02148.19 KII93965.1 - 1.3 9.4 5.1 5.7 7.3 0.5 2.5 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Rubredoxin PF00301.20 KII93965.1 - 6 7.0 8.1 6.6 6.8 0.5 3.3 3 0 0 3 3 3 0 Rubredoxin RVT_1 PF00078.27 KII93966.1 - 6.5e-07 29.1 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KII93967.1 - 1.5e-05 24.8 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KII93967.1 - 0.00066 19.3 0.1 0.00099 18.7 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transposase_23 PF03017.14 KII93968.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase Methyltransf_16 PF10294.9 KII93969.1 - 1.2e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KII93969.1 - 3.3e-05 23.7 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KII93969.1 - 0.0031 17.1 0.1 0.0045 16.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KII93969.1 - 0.021 15.5 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bot1p PF12298.8 KII93970.1 - 9.3e-25 87.8 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MFS_1 PF07690.16 KII93971.1 - 3.3e-20 72.3 17.6 5.3e-20 71.6 17.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cpn60_TCP1 PF00118.24 KII93972.1 - 1.3e-154 515.5 2.3 1.5e-154 515.3 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HIRAN PF08797.11 KII93973.1 - 7.4e-17 61.1 0.0 6.4e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 HIRAN domain CDC45 PF02724.14 KII93974.1 - 1.3 7.2 9.5 0.6 8.3 6.9 1.6 2 0 0 2 2 2 0 CDC45-like protein KRAB PF01352.27 KII93976.1 - 0.18 11.5 0.0 20 4.9 0.0 2.3 2 0 0 2 2 2 0 KRAB box DUF3526 PF12040.8 KII93977.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) SNF2_N PF00176.23 KII93978.1 - 3.3e-59 200.4 0.0 4.4e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII93978.1 - 2.5e-15 56.8 0.0 5.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII93978.1 - 3.2e-07 30.5 0.1 2.6e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KII93978.1 - 1e-06 28.5 13.5 2.1e-06 27.5 13.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII93978.1 - 7.2e-06 25.8 12.9 0.0002 21.1 12.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 KII93978.1 - 3.6e-05 23.6 0.0 7.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 KII93978.1 - 7.3e-05 22.6 12.2 0.00013 21.8 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII93978.1 - 7.6e-05 22.6 8.4 0.00035 20.5 7.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII93978.1 - 0.00013 22.2 12.1 0.00031 21.0 12.1 1.7 1 0 0 1 1 1 1 Ring finger domain Patched PF02460.18 KII93978.1 - 0.0089 14.2 0.1 0.013 13.6 0.1 1.1 1 0 0 1 1 1 1 Patched family zf-C3HC4_4 PF15227.6 KII93978.1 - 0.022 14.9 12.2 0.046 13.9 12.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SWI2_SNF2 PF18766.1 KII93978.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase zf-RING_5 PF14634.6 KII93978.1 - 0.23 11.5 11.2 0.57 10.2 11.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 KII93978.1 - 1.3 8.9 5.6 2.9 7.8 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ADH_zinc_N PF00107.26 KII93980.1 - 5.1e-11 42.7 0.0 1.1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII93980.1 - 5.8e-07 29.4 0.1 2.2e-05 24.3 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII93980.1 - 0.066 14.3 0.2 0.38 11.8 0.2 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 KII93981.1 - 2.2e-22 79.9 0.1 3.3e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KII93981.1 - 4.3e-08 33.3 0.1 1.3e-07 31.7 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KII93981.1 - 1.2e-07 32.0 0.0 3.1e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KII93981.1 - 0.0001 22.8 0.0 0.00022 21.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KII93981.1 - 0.0004 19.4 0.0 0.00075 18.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family ApbA PF02558.16 KII93981.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.16 KII93981.1 - 0.07 13.8 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII93981.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 KII93982.1 - 5.5e-38 130.8 0.0 7.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII93982.1 - 1.2e-26 93.6 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII93982.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Ctr PF04145.15 KII93983.1 - 0.00011 22.8 2.2 0.00011 22.8 2.2 2.3 2 1 1 3 3 3 1 Ctr copper transporter family Pex24p PF06398.11 KII93983.1 - 0.038 13.0 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo5 PF09810.9 KII93984.1 - 9.9e-65 219.4 0.0 1.7e-53 182.5 0.0 2.9 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.20 KII93984.1 - 0.0064 16.3 6.3 0.75 9.8 2.0 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif FAM176 PF14851.6 KII93987.1 - 0.027 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 FAM176 family DUF4834 PF16118.5 KII93987.1 - 0.06 14.3 0.0 0.22 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) G0-G1_switch_2 PF15103.6 KII93987.1 - 0.089 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 G0/G1 switch protein 2 Sin3a_C PF16879.5 KII93988.1 - 2.9e-81 273.4 0.0 3.6e-80 269.8 0.0 2.7 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KII93988.1 - 7.6e-38 128.5 0.0 1.9e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KII93988.1 - 1.7e-35 120.9 9.6 8.8e-17 61.0 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Zn-C2H2_12 PF18112.1 KII93988.1 - 0.0015 18.9 0.1 0.0033 17.8 0.1 1.6 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain GBP_C PF02841.14 KII93988.1 - 0.0055 16.2 0.4 0.0098 15.3 0.4 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MLANA PF14991.6 KII93989.1 - 0.09 13.1 0.4 0.93 9.8 0.0 2.7 1 1 2 3 3 3 0 Protein melan-A FAM176 PF14851.6 KII93989.1 - 0.1 12.3 1.1 9.8 5.8 0.0 2.9 2 1 1 3 3 3 0 FAM176 family F-box-like PF12937.7 KII93990.1 - 7.5e-08 32.1 0.2 2.7e-07 30.4 0.2 2.1 1 0 0 1 1 1 1 F-box-like HEAT_EZ PF13513.6 KII93991.1 - 2.2e-05 24.8 1.5 4.9 7.8 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KII93991.1 - 0.007 16.7 0.5 4.7 7.7 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 KII93991.1 - 0.0094 16.0 6.9 0.011 15.8 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KII93991.1 - 0.043 14.1 4.2 1.7 9.1 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 KII93991.1 - 0.061 13.4 0.0 0.51 10.4 0.0 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 KII93991.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 VHS domain Mg-por_mtran_C PF07109.11 KII93992.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus F-box-like PF12937.7 KII93994.1 - 0.0036 17.2 0.1 0.0092 15.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII93994.1 - 9.9 6.7 9.5 3.3 8.3 0.5 4.3 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Wbp11 PF09429.10 KII93995.1 - 2.1e-22 79.3 10.8 4.1e-22 78.4 10.8 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KII93995.1 - 3.4e-15 56.5 2.9 3.4e-15 56.5 2.9 9.5 5 1 1 6 6 6 1 mRNA biogenesis factor TMPIT PF07851.13 KII93995.1 - 6.4 5.9 5.1 23 4.1 0.1 2.0 2 0 0 2 2 2 0 TMPIT-like protein zf-C3HC4 PF00097.25 KII93996.1 - 3.9e-09 36.2 7.8 6.8e-09 35.5 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII93996.1 - 6.5e-08 32.5 9.5 7e-07 29.2 6.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII93996.1 - 1.7e-07 31.4 10.4 2.8e-07 30.8 10.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KII93996.1 - 4.6e-07 29.6 8.2 5.2e-06 26.2 9.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII93996.1 - 9.5e-06 25.7 10.1 1.5e-05 25.0 10.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KII93996.1 - 1.1e-05 25.2 6.7 1.8e-05 24.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII93996.1 - 4.4e-05 23.3 6.4 9.1e-05 22.3 6.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII93996.1 - 0.0019 18.0 7.2 0.0041 17.0 7.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KII93996.1 - 0.0094 15.7 5.8 0.018 14.9 5.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 KII93996.1 - 0.02 15.2 6.2 0.04 14.2 6.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 KII93996.1 - 0.14 11.9 9.0 0.27 11.0 9.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 KII93996.1 - 0.21 11.7 4.3 0.38 10.8 4.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 KII93996.1 - 0.62 10.2 1.8 1.2 9.3 1.8 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_11 PF17123.5 KII93996.1 - 0.64 9.8 10.1 2.1 8.2 5.8 2.6 2 0 0 2 2 2 0 RING-like zinc finger SH3_1 PF00018.28 KII93997.1 - 2.5e-11 43.0 0.1 4.4e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII93997.1 - 1e-08 34.7 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII93997.1 - 2.3e-07 30.6 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ECF_trnsprt PF12822.7 KII93998.1 - 1.3 9.1 9.7 7.1 6.7 6.7 2.1 1 1 1 2 2 2 0 ECF transporter, substrate-specific component AzlD PF05437.12 KII93998.1 - 2.5 8.3 9.7 0.94 9.7 2.3 2.9 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) FtsX PF02687.21 KII93998.1 - 9.2 6.8 8.8 5.5 7.5 3.6 2.7 3 0 0 3 3 3 0 FtsX-like permease family SET PF00856.28 KII94000.1 - 2e-10 41.4 0.0 5.2e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KII94000.1 - 0.13 12.9 0.0 5.1 7.8 0.0 2.4 2 0 0 2 2 2 0 SAF domain MAPEG PF01124.18 KII94001.1 - 0.0014 18.6 3.6 0.0039 17.1 3.6 1.8 1 1 0 1 1 1 1 MAPEG family UQ_con PF00179.26 KII94003.1 - 6e-26 90.8 0.0 1.3e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KII94003.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain UBA2_C PF16195.5 KII94003.1 - 3.5 8.4 10.7 1.7 9.4 2.0 2.9 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus ICL PF00463.21 KII94004.1 - 1e-192 641.3 0.1 1.2e-192 641.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KII94004.1 - 1e-09 38.3 3.3 1.3e-08 34.6 0.0 3.0 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase PapA_C PF16911.5 KII94004.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus FAD_binding_4 PF01565.23 KII94006.1 - 5.5e-19 68.3 0.1 1e-18 67.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KII94006.1 - 2.1e-08 34.1 0.7 4.4e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like HLH PF00010.26 KII94007.1 - 5.2e-11 42.3 0.9 5.2e-11 42.3 0.9 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TolA_bind_tri PF16331.5 KII94007.1 - 0.0001 22.3 1.7 0.0001 22.3 1.7 1.9 2 0 0 2 2 2 1 TolA binding protein trimerisation Spc29 PF17082.5 KII94007.1 - 0.029 14.2 2.3 0.038 13.8 2.3 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 APG6_N PF17675.1 KII94007.1 - 0.06 13.9 5.4 0.085 13.4 5.4 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Mt_ATP-synt_B PF05405.14 KII94007.1 - 0.082 12.5 1.7 0.1 12.2 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Peptidase_C21 PF05381.12 KII94007.1 - 0.086 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Tymovirus endopeptidase Mito_fiss_reg PF05308.11 KII94007.1 - 0.2 11.7 4.3 0.29 11.2 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator FapA PF03961.13 KII94007.1 - 0.69 8.4 3.0 0.87 8.1 3.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 KII94007.1 - 4.9 7.0 8.1 3.2 7.6 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator Mtp PF03821.16 KII94008.1 - 0.066 12.8 0.5 0.099 12.2 0.4 1.4 1 1 0 1 1 1 0 Golgi 4-transmembrane spanning transporter MASE2 PF05230.11 KII94008.1 - 9.3 6.4 10.1 0.085 12.9 1.4 2.1 3 0 0 3 3 3 0 MASE2 domain HLH PF00010.26 KII94009.1 - 7.9e-10 38.6 1.7 1.6e-09 37.5 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TBCA PF02970.16 KII94011.1 - 2.4e-22 79.1 0.5 3.4e-22 78.6 0.4 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Med11 PF10280.9 KII94012.1 - 0.00068 20.1 0.4 0.0039 17.6 0.4 2.3 1 1 0 1 1 1 1 Mediator complex protein Het-C PF07217.11 KII94013.1 - 6.1e-211 701.8 0.0 8.2e-211 701.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Bromodomain PF00439.25 KII94014.1 - 2.4e-56 187.8 0.0 2.7e-18 65.8 0.1 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KII94014.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KII94014.1 - 0.06 13.5 0.1 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain LTV PF04180.14 KII94015.1 - 1.3e-97 328.0 10.1 2.5e-89 300.7 11.4 2.1 1 1 1 2 2 2 2 Low temperature viability protein PIP5K PF01504.18 KII94016.1 - 4.4e-46 157.3 0.2 2e-37 128.9 0.2 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KII94016.1 - 6.3e-29 100.9 0.0 1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KII94016.1 - 1.4e-16 60.3 14.9 1.8e-16 60.0 12.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger Ribosomal_S27e PF01667.17 KII94016.1 - 0.44 10.3 2.2 1.1 9.0 2.2 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 IBR PF01485.21 KII94016.1 - 0.5 10.6 11.9 0.073 13.3 7.2 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain UCH PF00443.29 KII94018.1 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KII94018.1 - 1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rsm22 PF09243.10 KII94019.1 - 9.5e-44 149.7 0.0 1.4e-40 139.3 0.0 3.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.21 KII94020.1 - 1.3e-23 83.8 0.0 1.9e-23 83.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.9 KII94021.1 - 5.5e-11 42.9 2.4 2.2e-09 37.6 0.9 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 ARA70 PF12489.8 KII94021.1 - 0.0011 19.2 0.1 0.0022 18.2 0.1 1.5 2 0 0 2 2 2 1 Nuclear coactivator PCI PF01399.27 KII94022.1 - 2.2e-19 69.9 0.2 6.8e-19 68.3 0.2 1.9 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KII94022.1 - 0.036 14.3 4.9 0.1 12.9 0.6 3.3 3 1 0 3 3 3 0 Family of unknown function (DUF5517) DUF3626 PF12294.8 KII94022.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Rep_4 PF05797.11 KII94022.1 - 0.12 11.5 0.6 0.23 10.5 0.6 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) dsrm PF00035.26 KII94023.1 - 1.1e-09 38.9 0.0 1.2e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.26 KII94024.1 - 1.9e-07 31.7 0.0 5.2e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Double-stranded RNA binding motif WD40 PF00400.32 KII94026.1 - 4.4e-40 134.9 19.1 2.2e-07 31.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94026.1 - 1.1e-16 60.9 0.0 0.004 17.4 0.1 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII94026.1 - 0.0012 18.7 0.0 0.9 9.4 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KII94026.1 - 0.0022 17.4 0.0 0.78 9.0 0.0 3.3 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 KII94026.1 - 0.0061 15.6 0.3 10 4.9 0.0 3.8 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Sfi1_C PF10638.9 KII94027.1 - 0.76 10.6 4.6 1.9 9.2 0.0 3.5 3 0 0 3 3 3 0 Spindle body associated protein C-terminus MMM1 PF10296.9 KII94029.1 - 6.5e-08 32.0 0.0 4.9e-07 29.1 0.0 2.3 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_9 PF15410.6 KII94029.1 - 0.087 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 KII94029.1 - 0.2 12.1 0.0 0.58 10.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain NCBP3 PF10309.9 KII94031.1 - 2.3e-07 30.6 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KII94031.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain RunxI PF08504.11 KII94031.1 - 0.33 11.7 4.2 3.2 8.5 0.3 2.7 1 1 0 2 2 2 0 Runx inhibition domain SIKE PF05769.11 KII94032.1 - 2.7e-11 43.7 11.2 3.5e-07 30.3 7.7 2.2 2 0 0 2 2 2 2 SIKE family DivIC PF04977.15 KII94032.1 - 0.57 10.0 6.5 10 5.9 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator LSPR PF06049.12 KII94032.1 - 0.93 9.6 4.3 34 4.9 0.1 3.6 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat ZapB PF06005.12 KII94032.1 - 1.1 9.8 8.6 6.9 7.2 1.4 3.4 3 1 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 KII94032.1 - 2.3 8.9 11.0 18 6.1 2.3 3.4 2 1 1 3 3 3 0 Initiation control protein YabA SlyX PF04102.12 KII94032.1 - 2.3 8.9 15.3 1.4 9.6 0.5 4.7 3 1 2 5 5 5 0 SlyX DSHCT PF08148.12 KII94033.1 - 7e-52 175.4 0.1 1.4e-51 174.4 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KII94033.1 - 7.7e-36 122.9 0.0 1.3e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KII94033.1 - 2.3e-30 106.4 0.0 3.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KII94033.1 - 6.5e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII94033.1 - 5e-06 26.6 0.0 9.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII94033.1 - 3.4e-05 24.1 0.0 0.0001 22.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 KII94033.1 - 0.12 11.4 0.4 0.29 10.2 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) Methyltransf_31 PF13847.6 KII94035.1 - 2.8e-31 108.4 0.0 3.7e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII94035.1 - 8.1e-26 90.6 0.0 1.6e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII94035.1 - 2.2e-25 89.1 0.0 5.8e-25 87.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KII94035.1 - 7.3e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KII94035.1 - 3.5e-16 59.5 0.0 5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII94035.1 - 8.3e-16 58.6 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KII94035.1 - 5e-10 39.5 0.0 7.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KII94035.1 - 1.2e-08 34.7 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 KII94035.1 - 2e-07 30.6 0.0 3.4e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KII94035.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KII94035.1 - 0.00019 20.4 0.0 0.00047 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 KII94035.1 - 0.00032 20.4 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_29 PF03141.16 KII94035.1 - 0.00033 19.3 0.5 0.00052 18.7 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 KII94035.1 - 0.00039 19.8 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KII94035.1 - 0.00055 19.3 0.0 0.00065 19.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 KII94035.1 - 0.0018 17.4 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 KII94035.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 KII94035.1 - 0.0027 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 KII94035.1 - 0.058 12.8 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KII94035.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 KII94035.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ist1 PF03398.14 KII94036.1 - 2.8e-65 219.2 3.2 3.4e-65 218.9 3.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Methyltransf_23 PF13489.6 KII94038.1 - 9.2e-11 41.9 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII94038.1 - 1e-07 32.6 0.0 2.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII94038.1 - 6.7e-07 29.9 0.0 2e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KII94038.1 - 5.4e-05 22.7 0.0 0.00045 19.7 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 KII94038.1 - 9.2e-05 23.0 0.0 0.00023 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII94038.1 - 0.00013 21.8 0.0 0.0014 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KII94038.1 - 0.00037 20.7 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KII94038.1 - 0.0025 17.2 0.0 0.0058 16.0 0.0 1.6 2 1 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KII94038.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RasGEF PF00617.19 KII94039.1 - 1.7e-43 148.9 0.1 3e-43 148.1 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII94039.1 - 1.9e-18 66.6 0.1 4e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KII94039.1 - 6.8e-12 44.8 0.0 1.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII94039.1 - 4.8e-08 32.6 0.0 9.8e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII94039.1 - 1.4e-06 28.0 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ras PF00071.22 KII94040.1 - 3.7e-59 199.0 0.1 4.3e-59 198.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII94040.1 - 1.6e-36 125.1 0.0 2.2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII94040.1 - 1.2e-13 50.9 0.1 1.4e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII94040.1 - 2.6e-06 27.5 0.0 4.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII94040.1 - 1e-05 25.5 0.1 0.076 12.9 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KII94040.1 - 2.4e-05 23.8 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII94040.1 - 3.1e-05 23.6 0.0 7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KII94040.1 - 0.0045 17.4 0.3 0.012 16.0 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KII94040.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KII94040.1 - 0.053 13.0 0.1 0.17 11.3 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KII94040.1 - 0.14 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein RRM_1 PF00076.22 KII94041.1 - 4e-14 52.2 0.1 1e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94041.1 - 0.067 12.8 0.0 7.1 6.2 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KII94042.1 - 1.5e-17 63.7 20.3 0.00045 21.0 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF1391 PF07151.12 KII94042.1 - 0.18 11.6 1.8 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1391) Nup160 PF11715.8 KII94042.1 - 0.23 10.1 0.8 9.7 4.7 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 KII94043.1 - 8e-45 149.9 4.2 1.6e-09 38.2 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94043.1 - 2.2e-19 69.5 0.2 2.2e-08 34.3 0.0 5.6 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII94043.1 - 7.7e-07 29.2 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KII94043.1 - 2e-06 27.5 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KII94043.1 - 0.00021 20.4 0.0 3.5 6.5 0.0 4.5 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KII94043.1 - 0.00025 19.7 0.0 0.45 9.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 KII94043.1 - 0.0037 16.6 0.0 0.72 9.1 0.0 2.8 2 1 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 KII94043.1 - 0.013 14.8 0.1 0.43 9.9 0.0 2.9 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KII94043.1 - 0.016 15.1 0.0 1.9 8.5 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KII94043.1 - 0.029 13.0 0.0 0.16 10.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Bax1-I PF01027.20 KII94044.1 - 2.4e-38 132.1 7.5 2.4e-38 132.1 7.5 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.23 KII94045.1 - 1.9e-122 410.4 0.0 2.3e-122 410.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Qua1 PF16274.5 KII94045.1 - 0.19 11.6 1.0 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Qua1 domain RVT_1 PF00078.27 KII94046.1 - 4.7e-07 29.6 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 KII94046.1 - 0.06 14.1 0.4 0.25 12.1 0.3 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 KII94047.1 - 5.9e-10 39.0 0.0 7.5e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RSN1_7TM PF02714.15 KII94048.1 - 2e-09 37.1 17.6 4e-09 36.2 17.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KII94048.1 - 0.00026 21.1 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RSN1_TM PF13967.6 KII94048.1 - 0.00032 20.5 0.3 0.00032 20.5 0.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport bZIP_1 PF00170.21 KII94048.1 - 0.073 13.2 0.6 0.15 12.2 0.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor RicinB_lectin_2 PF14200.6 KII94049.1 - 0.009 16.7 0.0 0.079 13.7 0.0 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Arginase PF00491.21 KII94050.1 - 2.8e-85 286.2 0.0 3.5e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KII94050.1 - 0.047 13.9 0.1 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 UPF0489 domain SUR7 PF06687.12 KII94051.1 - 2e-19 70.1 17.1 2.7e-19 69.7 17.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KII94051.1 - 8.1 5.9 10.3 0.22 11.0 3.6 1.7 2 0 0 2 2 2 0 Clc-like Acetyltransf_3 PF13302.7 KII94052.1 - 1.2e-19 71.4 0.0 2e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII94052.1 - 0.00042 20.5 0.0 0.00065 19.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII94052.1 - 0.039 14.4 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII94052.1 - 0.051 13.5 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein GTP_EFTU PF00009.27 KII94053.1 - 2.7e-67 226.1 0.2 3.9e-67 225.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KII94053.1 - 1.1e-33 115.5 0.0 2.4e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KII94053.1 - 4.7e-21 74.6 0.0 1.1e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KII94053.1 - 6e-13 48.7 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KII94053.1 - 7.9e-10 39.0 0.0 2.4e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII94053.1 - 0.00015 21.9 0.2 0.00029 20.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII94053.1 - 0.14 12.1 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Metallophos PF00149.28 KII94054.1 - 2.3e-10 41.3 1.1 4.2e-10 40.5 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SRP68 PF16969.5 KII94055.1 - 8e-82 276.0 7.2 5.6e-81 273.2 1.4 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 ArsA_ATPase PF02374.15 KII94056.1 - 4.4e-110 367.6 1.0 5e-110 367.5 1.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KII94056.1 - 1.2e-13 51.4 0.1 7.3e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KII94056.1 - 1.4e-12 47.8 0.0 3.3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KII94056.1 - 6.6e-06 25.8 0.0 3.8e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KII94056.1 - 2.1e-05 24.1 0.0 7e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KII94056.1 - 6.6e-05 22.5 4.0 9.9e-05 21.9 0.6 2.7 2 2 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KII94056.1 - 0.00013 21.6 0.5 0.0036 17.0 0.1 2.6 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KII94056.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KII94056.1 - 0.0056 16.3 0.4 0.046 13.3 0.4 2.2 1 1 0 1 1 1 1 AAA domain VirC1 PF07015.11 KII94056.1 - 0.097 11.9 1.0 0.2 10.9 0.1 1.9 2 1 0 2 2 2 0 VirC1 protein PhoH PF02562.16 KII94056.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein bZIP_1 PF00170.21 KII94057.1 - 7.7e-12 45.1 13.5 1.7e-11 44.0 13.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KII94057.1 - 8.4e-05 22.5 0.0 8.4e-05 22.5 0.0 4.0 1 1 2 4 4 4 1 Transcription factor PAP1 SHE3 PF17078.5 KII94057.1 - 0.0014 18.4 6.7 0.0029 17.3 6.7 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Tmemb_cc2 PF10267.9 KII94057.1 - 0.0084 15.3 1.0 0.0084 15.3 1.0 2.2 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein DivIC PF04977.15 KII94057.1 - 0.019 14.7 1.5 0.019 14.7 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 KII94057.1 - 0.085 13.5 1.4 0.22 12.2 1.4 1.7 1 0 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 KII94057.1 - 0.26 9.2 1.1 0.36 8.7 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 KII94057.1 - 1.4 7.4 25.8 1.2 7.6 5.8 2.1 2 0 0 2 2 2 0 Macoilin family XhlA PF10779.9 KII94057.1 - 4.9 7.4 4.7 8.9 6.6 4.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Isochorismatase PF00857.20 KII94059.1 - 8.3e-07 29.3 0.0 7e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Isochorismatase family Sde2_N_Ubi PF13019.6 KII94059.1 - 0.055 13.3 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Isochorismatase PF00857.20 KII94060.1 - 8.5e-07 29.3 0.0 9.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family OppC_N PF12911.7 KII94061.1 - 0.041 13.9 2.4 0.048 13.6 1.1 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Frag1 PF10277.9 KII94061.1 - 0.049 13.2 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Ras PF00071.22 KII94063.1 - 1.1e-53 181.1 0.0 1.3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII94063.1 - 4.2e-32 110.9 0.0 5.9e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII94063.1 - 1.5e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII94063.1 - 1.4e-05 24.7 0.0 0.00046 19.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KII94063.1 - 0.00031 20.8 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII94063.1 - 0.00036 19.9 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KII94063.1 - 0.0025 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KII94063.1 - 0.012 16.0 0.3 0.032 14.6 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KII94063.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KII94063.1 - 0.016 15.4 0.1 0.042 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KII94063.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 KaiC ATP_bind_1 PF03029.17 KII94063.1 - 0.022 14.5 0.0 0.74 9.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 KII94063.1 - 0.026 13.7 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 KII94063.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dehydrin PF00257.19 KII94063.1 - 0.031 14.8 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 Dehydrin RsgA_GTPase PF03193.16 KII94063.1 - 0.044 13.7 0.0 2 8.3 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KII94063.1 - 0.049 14.1 0.0 0.16 12.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 KII94063.1 - 0.073 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Septin DUF2075 PF09848.9 KII94063.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) D-ser_dehydrat PF14031.6 KII94064.1 - 3e-24 85.5 0.6 4.6e-23 81.7 0.0 2.7 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KII94064.1 - 4.2e-10 39.6 0.1 5.9e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.13 KII94065.1 - 2.3e-64 217.1 0.0 3.1e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII94065.1 - 2.3e-10 40.0 1.4 6.6e-10 38.5 1.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KII94065.1 - 7.3e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KII94065.1 - 1.5e-05 24.1 0.0 1.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase PF07224.11 KII94065.1 - 3.5e-05 23.0 0.0 8e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase Peptidase_S9 PF00326.21 KII94065.1 - 0.00033 20.2 0.0 0.0019 17.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KII94065.1 - 0.057 13.0 0.3 0.22 11.1 0.3 1.9 1 1 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.13 KII94065.1 - 0.22 10.0 0.1 1.7 7.1 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II COX5A PF02284.16 KII94066.1 - 1.7e-42 143.6 0.5 2.3e-42 143.2 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Acetyltransf_1 PF00583.25 KII94067.1 - 1.9e-10 41.0 0.0 3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KII94067.1 - 2.4e-09 37.0 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KII94067.1 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KII94067.1 - 0.00012 22.1 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KII94067.1 - 0.00015 22.5 0.0 0.00075 20.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII94067.1 - 0.00023 21.5 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII94067.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_P_pop3 PF08228.11 KII94068.1 - 1.1e-14 54.8 0.1 1.8e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 Rotamase_2 PF13145.6 KII94068.1 - 0.0011 19.8 5.3 0.0078 17.0 0.4 2.3 2 0 0 2 2 2 2 PPIC-type PPIASE domain Suf PF05843.14 KII94068.1 - 0.011 15.7 0.3 0.011 15.7 0.3 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) F-box PF00646.33 KII94069.1 - 0.00028 20.7 0.4 0.0016 18.3 0.4 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII94069.1 - 0.0013 18.5 0.0 0.0056 16.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like dCMP_cyt_deam_1 PF00383.23 KII94070.1 - 6.4e-25 87.0 0.5 1e-24 86.4 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII94070.1 - 4.8e-11 42.5 0.1 8.1e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase HEAT PF02985.22 KII94071.1 - 2.1e-05 24.4 0.4 0.032 14.5 0.0 4.4 3 0 0 3 3 3 2 HEAT repeat Chorismate_bind PF00425.18 KII94072.1 - 5.3e-68 229.4 0.0 7e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KII94072.1 - 6.1e-33 114.2 0.0 9.7e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KII94072.1 - 3.3e-14 53.3 0.0 7.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KII94072.1 - 2.4e-05 24.2 1.2 5.6e-05 23.0 1.2 1.5 1 1 0 1 1 1 1 Peptidase C26 F-box-like PF12937.7 KII94073.1 - 0.00033 20.5 0.6 0.00082 19.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like Homeodomain PF00046.29 KII94074.1 - 1.1e-15 57.2 1.3 1.8e-15 56.5 1.3 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII94074.1 - 0.00084 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 KII94074.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Methyltransf_24 PF13578.6 KII94076.1 - 5.4e-09 37.0 0.0 1.1e-08 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KII94076.1 - 0.13 11.4 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase PB1 PF00564.24 KII94077.1 - 1.8e-08 34.2 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain DUF4887 PF16228.5 KII94077.1 - 0.047 13.9 1.7 0.084 13.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Rrn6 PF10214.9 KII94077.1 - 0.11 11.0 4.1 0.21 10.0 4.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Aldo_ket_red PF00248.21 KII94078.1 - 1.9e-37 129.1 0.0 2.4e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ApbA_C PF08546.11 KII94079.1 - 3e-32 111.4 0.1 5.5e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KII94079.1 - 1.1e-19 70.6 0.4 6e-18 64.9 0.4 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KII94079.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain YrhK PF14145.6 KII94080.1 - 0.032 14.1 2.1 0.059 13.2 0.2 2.4 2 0 0 2 2 2 0 YrhK-like protein DUF872 PF05915.12 KII94080.1 - 0.05 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) O-FucT PF10250.9 KII94081.1 - 1.7e-13 51.0 0.0 3.4e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Fungal_trans_2 PF11951.8 KII94081.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPT PF03151.16 KII94082.1 - 4.7e-09 36.0 18.7 5.8e-09 35.7 18.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KII94082.1 - 1.9e-05 24.8 37.0 0.0057 16.8 16.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Arteri_Gl PF00951.18 KII94083.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein YccV-like PF08755.11 KII94085.1 - 3.5e-23 81.9 0.0 6.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KII94085.1 - 2.9e-09 36.7 0.0 5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Autoind_bind PF03472.15 KII94085.1 - 0.017 14.6 0.1 0.046 13.2 0.1 1.7 1 0 0 1 1 1 0 Autoinducer binding domain DUF1741 PF08427.10 KII94087.1 - 3.2e-33 115.3 0.2 9.2e-33 113.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) GDC-P PF02347.16 KII94088.1 - 2.2e-186 619.9 0.0 3.7e-175 582.9 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KII94088.1 - 4.4e-05 22.6 0.2 0.0002 20.4 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KII94088.1 - 7.5e-05 22.2 0.1 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase PPR_2 PF13041.6 KII94089.1 - 1.4e-27 95.6 0.0 0.017 15.3 0.0 9.6 7 2 2 9 9 9 7 PPR repeat family PPR PF01535.20 KII94089.1 - 1.9e-16 59.0 4.7 0.011 15.9 0.0 9.6 10 0 0 10 10 10 3 PPR repeat PPR_3 PF13812.6 KII94089.1 - 3.1e-12 46.4 0.0 0.078 13.1 0.0 7.7 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KII94089.1 - 3.6e-08 33.0 0.0 0.14 11.5 0.0 4.9 3 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KII94089.1 - 1.5e-07 31.0 0.1 3.5 7.4 0.0 8.1 9 0 0 9 9 9 1 PPR repeat FGase PF05013.12 KII94089.1 - 0.02 15.1 1.1 6.2 7.0 0.2 2.6 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase SecE PF00584.20 KII94090.1 - 4.8e-14 52.0 0.0 5.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex HHV-5_US34A PF17087.5 KII94091.1 - 8.8 6.6 8.4 4.1 7.6 1.6 3.1 4 0 0 4 4 4 0 Herpesvirus US34A protein family Vps51 PF08700.11 KII94092.1 - 1.5e-12 47.4 0.6 5.5e-12 45.6 0.6 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 KII94092.1 - 1.6 8.8 3.4 1.2 9.3 1.0 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1751 PF08551.10 KII94093.1 - 1.6e-23 83.1 2.5 3e-23 82.2 2.5 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) NADH_B2 PF14813.6 KII94093.1 - 0.19 11.6 1.3 1 9.2 0.1 2.2 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Ribosomal_60s PF00428.19 KII94093.1 - 0.85 10.3 3.6 1.4 9.5 3.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1754 PF08555.10 KII94094.1 - 1.4e-14 54.7 8.9 1.4e-14 54.7 8.9 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) GvpL_GvpF PF06386.11 KII94094.1 - 0.027 14.4 0.5 0.036 14.0 0.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4191 PF13829.6 KII94094.1 - 0.049 13.0 0.9 0.075 12.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) FAM27 PF15832.5 KII94094.1 - 1.3 9.7 10.3 0.1 13.1 1.2 2.2 1 1 1 2 2 2 0 FAM27 D and E protein family Mpp10 PF04006.12 KII94094.1 - 6.4 5.1 14.8 8.1 4.7 14.8 1.1 1 0 0 1 1 1 0 Mpp10 protein WSD PF15613.6 KII94095.1 - 0.0043 17.5 0.2 0.012 16.0 0.2 2.0 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 KII94095.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Peptidase_M3 PF01432.20 KII94096.1 - 2e-130 436.2 0.0 2.4e-130 435.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 CREPT PF16566.5 KII94096.1 - 0.11 12.7 0.4 0.73 10.0 0.0 2.5 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour SSTK-IP PF15836.5 KII94096.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Peptidase_M91 PF14891.6 KII94096.1 - 0.22 11.8 0.1 0.43 10.9 0.1 1.4 1 0 0 1 1 1 0 Effector protein Gp58 PF07902.11 KII94097.1 - 0.048 12.0 0.0 0.062 11.6 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein Mating_C PF12737.7 KII94098.1 - 1.1e-23 84.1 56.2 2.5e-12 46.8 33.1 3.2 2 1 1 3 3 3 2 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 KII94098.1 - 2.7e-12 46.4 0.1 1.2e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Mating_N PF12731.7 KII94098.1 - 2.5e-06 27.5 2.2 2.5e-06 27.5 2.2 1.8 2 0 0 2 2 2 1 Mating-type protein beta 1 MerR-DNA-bind PF09278.11 KII94098.1 - 0.067 13.7 0.2 0.067 13.7 0.2 2.8 3 0 0 3 3 3 0 MerR, DNA binding DUF4317 PF14199.6 KII94098.1 - 0.29 10.2 1.5 0.42 9.7 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Homeodomain PF00046.29 KII94099.1 - 7.6e-12 44.9 0.6 1.7e-11 43.8 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KII94099.1 - 1.4e-05 24.9 0.1 4.4e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KII94099.1 - 0.0056 16.1 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Mating_C PF12737.7 KII94101.1 - 1.8e-16 60.4 50.1 4.5e-11 42.6 10.8 3.7 2 1 1 3 3 3 2 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 KII94101.1 - 5.8e-12 45.3 0.1 2.1e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Mating_N PF12731.7 KII94101.1 - 5.6e-08 32.8 1.4 1.4e-07 31.5 1.4 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 DUF4317 PF14199.6 KII94101.1 - 0.0034 16.6 0.2 0.0048 16.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4317) MerR-DNA-bind PF09278.11 KII94101.1 - 0.012 16.2 0.4 0.012 16.2 0.4 2.5 2 0 0 2 2 2 0 MerR, DNA binding Homeodomain PF00046.29 KII94101.1 - 0.051 13.4 0.1 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Homeodomain DUF572 PF04502.13 KII94101.1 - 0.78 9.3 7.3 1.3 8.6 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1631 PF07793.11 KII94103.1 - 0.83 8.0 2.5 0.9 7.9 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Apolipoprotein PF01442.18 KII94104.1 - 8.9e-05 22.4 9.4 0.00015 21.7 1.6 2.6 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KII94104.1 - 0.0049 17.4 9.9 0.085 13.5 0.5 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 KII94104.1 - 0.13 12.3 1.5 9.3 6.3 0.1 2.7 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mitofilin PF09731.9 KII94104.1 - 0.72 8.6 8.2 0.88 8.3 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ATP-synt_B PF00430.18 KII94104.1 - 2.9 8.0 13.5 0.73 9.9 3.8 2.8 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Phasin_2 PF09361.10 KII94104.1 - 5.5 7.3 11.4 2.3 8.5 0.6 3.2 1 1 2 3 3 3 0 Phasin protein EF-hand_6 PF13405.6 KII94105.1 - 5.1e-11 41.6 1.7 7.9e-06 25.4 0.3 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KII94105.1 - 2e-09 37.8 3.2 5.2e-09 36.4 1.8 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KII94105.1 - 9.9e-06 24.7 8.2 0.00072 18.9 0.3 3.6 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 KII94105.1 - 0.0052 17.1 0.1 4 7.8 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KII94105.1 - 0.021 14.3 2.0 0.083 12.4 0.6 2.3 2 0 0 2 2 2 0 EF hand DUF1456 PF07308.13 KII94105.1 - 0.045 14.1 0.0 8 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) F-box-like PF12937.7 KII94106.1 - 1.1e-11 44.5 0.7 3e-11 43.0 0.7 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94106.1 - 1.2e-06 28.2 0.4 3e-06 26.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KII94106.1 - 0.019 15.4 3.1 0.24 11.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 KII94107.1 - 7.6e-45 152.8 0.7 1.1e-44 152.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII94107.1 - 5.5e-33 114.5 0.2 7.5e-33 114.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KII94107.1 - 9.5e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KII94107.1 - 1.4e-06 28.0 0.1 3e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KII94107.1 - 1.9e-05 24.7 0.2 3.2e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KII94107.1 - 0.0057 15.8 0.1 0.0087 15.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KII94107.1 - 0.017 14.5 0.2 0.06 12.7 0.1 1.9 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 KII94107.1 - 0.02 14.7 0.1 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CENP-S PF15630.6 KII94107.1 - 0.055 13.9 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 CENP-S protein PAP2 PF01569.21 KII94108.1 - 1.8e-14 53.6 10.2 6.2e-14 51.9 10.2 1.7 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KII94108.1 - 0.00022 21.4 0.7 0.0072 16.5 0.1 2.2 1 1 0 2 2 2 2 Divergent PAP2 family PI-PLC-X PF00388.19 KII94109.1 - 0.0048 16.5 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-C1 PF16670.5 KII94109.1 - 0.0073 15.4 0.3 0.67 9.0 0.0 3.0 2 2 1 3 3 3 1 Phosphoinositide phospholipase C, Ca2+-dependent Sigma54_AID PF00309.20 KII94109.1 - 0.0085 15.9 1.9 0.019 14.8 1.9 1.5 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) Talin_middle PF09141.10 KII94109.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Talin, middle domain Utp11 PF03998.13 KII94110.1 - 1.9e-73 247.4 21.7 3e-73 246.8 21.7 1.3 1 0 0 1 1 1 1 Utp11 protein Vpu PF00558.19 KII94110.1 - 0.067 13.0 0.1 0.067 13.0 0.1 2.8 3 0 0 3 3 3 0 Vpu protein SLATT_5 PF18160.1 KII94110.1 - 0.15 11.3 0.4 0.28 10.5 0.4 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Red1 PF07964.11 KII94110.1 - 3 6.0 10.5 0.17 10.1 5.2 1.6 2 0 0 2 2 2 0 Rec10 / Red1 Nucleo_P87 PF07267.11 KII94110.1 - 3.2 6.5 12.6 0.15 10.9 6.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 VHS PF00790.19 KII94112.1 - 2.9e-28 98.5 0.0 5.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KII94112.1 - 1.5e-09 38.0 0.5 2e-07 31.2 0.8 2.5 2 0 0 2 2 2 1 GAT domain CAF-1_p150 PF11600.8 KII94112.1 - 0.01 15.5 18.5 0.01 15.5 18.5 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cnd1_N PF12922.7 KII94112.1 - 0.51 10.2 4.2 1.7 8.5 4.2 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NARP1 PF12569.8 KII94112.1 - 2.9 6.7 19.8 1.7 7.5 0.0 2.4 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 KII94112.1 - 4.5 7.3 6.6 13 5.8 6.6 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF719 PF05334.13 KII94112.1 - 8.2 6.6 9.1 0.43 10.7 1.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF719) zf-RING_2 PF13639.6 KII94113.1 - 1.3e-11 44.6 4.3 1.3e-11 44.6 4.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KII94113.1 - 4.3e-11 42.4 2.6 4.3e-11 42.4 2.6 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KII94113.1 - 1.1e-06 28.5 2.1 1.9e-06 27.8 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PA PF02225.22 KII94113.1 - 1.5e-06 28.1 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KII94113.1 - 5.2e-06 26.2 3.4 1e-05 25.3 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII94113.1 - 7.7e-05 22.5 2.6 0.00014 21.7 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII94113.1 - 0.00036 20.3 2.1 0.00071 19.4 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII94113.1 - 0.0018 18.2 4.5 0.0089 16.0 0.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KII94113.1 - 0.0034 17.6 8.9 0.0061 16.8 7.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII94113.1 - 0.043 13.9 1.4 0.12 12.4 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KII94113.1 - 0.07 13.0 3.0 0.18 11.7 3.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KII94113.1 - 0.47 10.1 3.1 0.9 9.2 3.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KII94113.1 - 1 9.6 5.7 3.4 7.9 3.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain tRNA-synt_2b PF00587.25 KII94114.1 - 1.8e-22 80.2 0.0 3.2e-22 79.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KII94114.1 - 4.6e-08 33.2 0.6 7.1e-08 32.6 0.6 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rep_fac_C PF08542.11 KII94115.1 - 4.9e-26 90.9 0.0 1.3e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KII94115.1 - 2.6e-12 46.8 0.1 2.5e-10 40.4 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KII94115.1 - 5.3e-12 46.3 0.1 8.4e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KII94115.1 - 1.6e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII94115.1 - 1.9e-06 28.4 0.0 0.00032 21.1 0.0 2.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KII94115.1 - 3.3e-06 27.4 0.1 0.0028 17.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KII94115.1 - 3e-05 23.9 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KII94115.1 - 5.1e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KII94115.1 - 0.00039 20.2 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KII94115.1 - 0.0011 18.8 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit MeaB PF03308.16 KII94115.1 - 0.0045 16.0 0.0 0.0098 14.9 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 KII94115.1 - 0.0045 16.4 0.0 0.05 13.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KII94115.1 - 0.0047 16.9 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 KII94115.1 - 0.014 15.2 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 KII94115.1 - 0.015 15.6 0.0 0.041 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain NTPase_1 PF03266.15 KII94115.1 - 0.022 14.6 0.2 0.087 12.7 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.6 KII94115.1 - 0.045 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KII94115.1 - 0.049 14.0 0.0 0.19 12.1 0.0 2.0 1 1 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KII94115.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KII94115.1 - 0.1 12.9 0.2 0.89 9.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KII94115.1 - 0.1 13.1 0.1 0.26 11.8 0.1 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 KII94115.1 - 0.13 11.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein KTI12 PF08433.10 KII94115.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ParA PF10609.9 KII94116.1 - 6.2e-87 291.1 0.0 7.8e-87 290.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 KII94116.1 - 2.7e-06 26.8 0.4 0.00062 19.0 0.1 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 KII94116.1 - 6e-06 26.3 0.0 2.5e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KII94116.1 - 3.9e-05 23.6 0.0 0.018 15.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 KII94116.1 - 0.00065 19.1 0.1 0.0082 15.5 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 KII94116.1 - 0.0062 16.1 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KII94116.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KII94116.1 - 0.024 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KII94116.1 - 0.099 13.2 0.1 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KII94116.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KII94116.1 - 0.16 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF3759 PF12585.8 KII94117.1 - 1.5e-35 121.1 6.5 1.8e-35 120.8 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) adh_short PF00106.25 KII94121.1 - 3.6e-48 163.6 1.4 4.6e-48 163.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII94121.1 - 1.9e-34 119.2 0.1 2.5e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII94121.1 - 5e-10 39.6 0.1 8.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII94121.1 - 4e-08 33.0 0.0 4.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KII94121.1 - 7.6e-08 32.1 0.2 3.1e-07 30.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII94121.1 - 0.0073 15.7 0.1 0.065 12.6 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 KII94121.1 - 0.0098 15.7 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 KII94121.1 - 0.012 14.7 0.2 0.018 14.2 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CENP-S PF15630.6 KII94121.1 - 0.11 12.9 0.0 9.5 6.7 0.0 2.7 3 0 0 3 3 3 0 CENP-S protein RRM_1 PF00076.22 KII94122.1 - 6.9e-13 48.2 0.0 4.4e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94122.1 - 0.038 13.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KII94122.1 - 0.25 11.2 0.0 0.67 9.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RNA_pol_Rpb6 PF01192.22 KII94123.1 - 3e-15 55.9 0.1 3.7e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4549 PF15082.6 KII94123.1 - 0.21 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) HORMA PF02301.18 KII94124.1 - 5.3e-08 32.7 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 HORMA domain PX PF00787.24 KII94125.1 - 7.2e-20 71.1 0.3 4.6e-19 68.5 0.5 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KII94125.1 - 0.0004 20.0 3.6 0.00082 19.0 1.9 2.3 1 1 0 2 2 2 1 Vps5 C terminal like BAR_3 PF16746.5 KII94125.1 - 0.023 14.4 0.1 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 BAR domain of APPL family Lung_7-TM_R PF06814.13 KII94126.1 - 1.4e-62 211.6 14.3 1.8e-62 211.3 14.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF996 PF06195.13 KII94126.1 - 2.2 8.6 13.9 9.4 6.5 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF996) SafA PF17073.5 KII94126.1 - 4.8 7.2 5.6 0.47 10.5 0.5 2.0 2 0 0 2 2 2 0 Two-component-system connector protein RNA_pol_Rpb2_6 PF00562.28 KII94128.1 - 6.9e-126 420.4 0.2 9.7e-126 419.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KII94128.1 - 2.6e-69 232.8 0.0 3.8e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KII94128.1 - 3.9e-48 163.6 0.1 7.3e-48 162.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KII94128.1 - 3.9e-32 110.5 0.1 1e-31 109.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KII94128.1 - 2e-26 92.0 0.2 6.2e-26 90.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KII94128.1 - 6.6e-26 90.3 0.1 1.6e-25 89.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KII94128.1 - 2.9e-21 75.8 0.2 8.5e-21 74.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KII94128.1 - 0.22 12.3 0.8 0.64 10.8 0.8 1.7 1 0 0 1 1 1 0 MRN-interacting protein Macoilin PF09726.9 KII94129.1 - 3.6 6.0 6.9 1.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Macoilin family Myb_DNA-bind_7 PF15963.5 KII94131.1 - 1.3e-22 79.5 0.1 3.4e-22 78.1 0.1 1.7 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KII94131.1 - 8.7e-09 35.4 0.0 2.4e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII94131.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SIR2 PF02146.17 KII94132.1 - 2.7e-27 95.8 0.2 1.9e-23 83.3 0.0 3.1 2 1 0 2 2 2 2 Sir2 family Ribonuclease_T2 PF00445.18 KII94133.1 - 5.4e-40 137.6 0.1 7.5e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family FIST PF08495.10 KII94133.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 FIST N domain MSC PF09402.10 KII94133.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain MBOAT_2 PF13813.6 KII94134.1 - 6.8e-13 48.7 0.9 2.1e-12 47.1 0.9 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF5464 PF17552.2 KII94134.1 - 0.091 13.0 7.5 0.098 12.9 2.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5464) SURF1 PF02104.15 KII94136.1 - 9.1e-45 153.0 0.0 1.2e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.16 KII94137.1 - 7.4e-74 248.2 0.0 7.4e-74 248.2 0.0 3.3 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KII94137.1 - 3.9e-55 186.3 10.4 3.9e-55 186.3 10.4 5.6 4 1 2 7 7 7 1 I/LWEQ domain ENTH PF01417.20 KII94137.1 - 0.0015 18.5 0.1 0.022 14.8 0.0 3.0 2 1 0 2 2 2 1 ENTH domain FAA_hydro_N_2 PF18288.1 KII94137.1 - 0.0016 18.8 1.9 0.018 15.5 0.5 3.4 1 1 1 2 2 2 1 Fumarylacetoacetase N-terminal domain 2 Ion_trans PF00520.31 KII94139.1 - 6.4e-05 22.3 2.7 8.6e-05 21.9 2.7 1.1 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.8 KII94140.1 - 4.3e-25 88.6 0.3 4.3e-25 88.6 0.3 3.7 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KII94140.1 - 3.7e-14 52.6 12.4 3.7e-14 52.6 12.4 4.3 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR MFS_1 PF07690.16 KII94142.1 - 9.3e-47 159.7 34.9 1.7e-44 152.2 21.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII94142.1 - 6.7e-11 41.7 11.8 6.7e-11 41.7 11.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KII94142.1 - 2.5e-09 36.1 0.9 4.6e-09 35.3 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KII94142.1 - 0.00018 20.2 7.3 0.00018 20.2 7.3 2.4 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_3 PF05977.13 KII94142.1 - 0.0011 17.5 3.3 0.0019 16.7 3.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 KII94142.1 - 1.6 7.5 13.4 0.36 9.6 6.3 2.7 2 1 0 2 2 2 0 MFS_1 like family EptA_B_N PF08019.12 KII94142.1 - 3.5 7.5 8.0 0.24 11.3 0.4 2.9 3 0 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DivIC PF04977.15 KII94143.1 - 0.046 13.5 0.8 0.046 13.5 0.8 2.5 3 0 0 3 3 3 0 Septum formation initiator YabA PF06156.13 KII94143.1 - 0.11 13.2 0.1 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KII94143.1 - 1.2 9.7 4.7 3.1 8.3 0.1 2.9 3 1 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 KII94143.1 - 2.5 8.6 4.9 0.66 10.5 0.4 2.1 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF1910 PF08928.10 KII94144.1 - 0.18 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) zf-MYND PF01753.18 KII94145.1 - 2.5e-11 43.5 9.7 6.3e-11 42.2 9.7 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KII94145.1 - 0.1 12.7 4.3 0.21 11.7 4.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_transf_8 PF01501.20 KII94146.1 - 8.7e-20 71.3 0.0 3.6e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 SUZ-C PF12901.7 KII94147.1 - 0.18 11.9 0.4 0.26 11.3 0.4 1.2 1 0 0 1 1 1 0 SUZ-C motif ABC1 PF03109.16 KII94148.1 - 3.4e-22 78.8 0.0 2.8e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KII94148.1 - 0.036 14.0 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KII94149.1 - 2.6e-58 197.5 0.0 3.1e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KII94149.1 - 2.5e-09 37.4 0.0 5e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.7 KII94150.1 - 6.2e-08 32.4 2.1 1.9e-07 30.8 1.6 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII94150.1 - 0.025 15.0 0.5 14 6.2 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 KII94150.1 - 0.033 14.1 0.8 0.033 14.1 0.8 2.2 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KII94151.1 - 1.7e-10 40.6 1.2 5.8e-10 38.9 1.2 2.0 1 0 0 1 1 1 1 F-box-like GARS_A PF01071.19 KII94152.1 - 5.2e-77 258.0 0.0 7.5e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 KII94152.1 - 1.7e-34 119.2 0.0 5.1e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 KII94152.1 - 2.4e-33 114.8 0.0 1.7e-32 112.0 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KII94152.1 - 1.5e-28 98.9 0.9 3.7e-28 97.6 0.9 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KII94152.1 - 2e-15 57.2 1.7 3.4e-14 53.3 1.7 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KII94152.1 - 0.00029 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF5496 PF17600.2 KII94152.1 - 0.035 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5496) Ank_2 PF12796.7 KII94153.1 - 8.4e-09 35.9 0.0 1.4e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 KII94153.1 - 1.3e-08 34.5 14.5 0.00022 20.9 3.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KII94153.1 - 4.3e-07 30.2 18.8 1e-06 29.0 5.4 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_3 PF13606.6 KII94153.1 - 9.8e-06 25.6 0.0 9.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KII94153.1 - 1.4e-05 25.2 0.0 7e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-CCCH PF00642.24 KII94153.1 - 1.6e-05 24.6 12.8 0.01 15.8 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 KII94153.1 - 2e-05 25.0 0.0 5.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KII94153.1 - 5e-05 23.5 0.0 0.00017 21.9 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeat zf_CCCH_4 PF18345.1 KII94153.1 - 6.8e-05 22.8 17.1 0.00044 20.2 2.6 2.8 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 KII94153.1 - 0.001 19.7 0.4 0.001 19.7 0.4 2.3 2 0 0 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 KII94153.1 - 0.91 9.8 2.7 5.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family NAD_Gly3P_dh_C PF07479.14 KII94154.1 - 3.2e-50 170.1 0.2 5e-50 169.5 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KII94154.1 - 1.2e-33 116.3 0.0 2.6e-33 115.2 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KII94154.1 - 3.7e-09 36.4 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KII94154.1 - 2.2e-05 25.0 0.0 0.00016 22.2 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KII94154.1 - 0.0042 17.3 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 KII94154.1 - 0.073 13.3 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 KII94154.1 - 0.075 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SNARE PF05739.19 KII94155.1 - 2.2e-13 49.9 0.1 5e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KII94155.1 - 1.7e-06 27.1 0.2 1.7e-06 27.1 0.2 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KII94155.1 - 6.7e-06 25.9 9.7 6.7e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 Syntaxin Syntaxin-18_N PF10496.9 KII94155.1 - 0.00019 21.6 0.1 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1351 PF07083.11 KII94155.1 - 0.0015 18.3 2.5 0.0024 17.7 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) DUF16 PF01519.16 KII94155.1 - 0.26 11.8 0.2 0.26 11.8 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Peroxidase_2 PF01328.17 KII94155.1 - 0.65 10.5 3.2 1.2 9.7 1.5 1.9 1 1 1 2 2 2 0 Peroxidase, family 2 Osmo_CC PF08946.10 KII94155.1 - 1.1 9.5 4.0 2.5 8.4 0.3 3.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil ParB PF08775.10 KII94155.1 - 1.3 9.5 7.5 0.25 11.8 3.4 2.0 2 0 0 2 2 2 0 ParB family SlyX PF04102.12 KII94155.1 - 2.5 8.8 6.4 0.77 10.4 0.5 2.8 2 1 0 2 2 2 0 SlyX RRM_1 PF00076.22 KII94156.1 - 1.7e-09 37.4 0.0 3.9e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRFAP1 PF15155.6 KII94156.1 - 1.3 9.6 5.1 0.48 11.0 2.0 1.9 2 0 0 2 2 2 0 MORF4 family-associated protein1 DUF5401 PF17380.2 KII94157.1 - 0.11 10.6 0.1 0.11 10.6 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5401) MAPEG PF01124.18 KII94160.1 - 1.8e-19 69.9 0.5 2.2e-19 69.6 0.5 1.1 1 0 0 1 1 1 1 MAPEG family CAF1C_H4-bd PF12265.8 KII94161.1 - 4.7e-15 55.6 0.1 7.8e-14 51.7 0.0 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KII94161.1 - 4e-14 52.8 12.0 8.4e-05 23.3 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 KII94161.1 - 3.4e-05 23.8 0.2 0.00066 19.6 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 KII94161.1 - 0.00027 21.2 0.5 0.084 13.2 0.1 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KII94161.1 - 0.052 11.5 0.2 0.19 9.7 0.0 1.8 2 0 0 2 2 2 0 IKI3 family RXT2_N PF08595.11 KII94161.1 - 3.5 7.6 10.7 0.1 12.6 1.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal PA28_beta PF02252.18 KII94162.1 - 3.1e-53 179.4 2.0 5.2e-53 178.6 1.5 1.6 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KII94162.1 - 2e-07 30.9 0.1 4.9e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit SWC7 PF17330.2 KII94162.1 - 0.034 14.2 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 DUF3591 PF12157.8 KII94163.1 - 9.9e-189 627.6 0.3 1.6e-188 626.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KII94163.1 - 7.9e-05 22.4 3.7 0.00017 21.4 3.7 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KII94163.1 - 0.0011 19.1 0.1 0.0021 18.1 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain zf-CCHC PF00098.23 KII94163.1 - 0.78 9.9 3.3 1.4 9.1 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.26 KII94164.1 - 1.7e-06 28.1 17.4 0.00031 21.0 1.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KII94164.1 - 0.0021 18.3 0.3 0.0021 18.3 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KII94164.1 - 0.0028 18.3 1.1 0.0028 18.3 1.1 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 KII94164.1 - 0.014 15.8 5.8 0.024 15.0 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KII94164.1 - 0.67 10.6 16.2 0.81 10.4 0.7 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain F-box PF00646.33 KII94170.1 - 5e-06 26.3 0.6 3.7e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII94170.1 - 1.5e-05 24.8 0.1 5.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KII94170.1 - 0.0056 16.6 0.9 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box Med7 PF05983.11 KII94172.1 - 7.1e-50 169.8 0.1 8.6e-50 169.5 0.1 1.1 1 0 0 1 1 1 1 MED7 protein AMP-binding PF00501.28 KII94173.1 - 4.9e-81 272.5 0.0 6.5e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII94173.1 - 5.4e-13 49.7 0.8 2.8e-12 47.4 0.1 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ph1570 PF09638.10 KII94173.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Ph1570 protein Drc1-Sld2 PF11719.8 KII94175.1 - 2.4e-16 60.4 0.6 2.4e-16 60.4 0.6 3.1 2 1 0 3 3 3 1 DNA replication and checkpoint protein GEN1_C PF18380.1 KII94175.1 - 1.1 10.2 0.0 1.1 10.2 0.0 2.8 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pal1 PF08316.11 KII94176.1 - 0.0017 19.1 0.0 0.005 17.6 0.0 1.8 1 0 0 1 1 1 1 Pal1 cell morphology protein PCI PF01399.27 KII94179.1 - 1.5e-18 67.3 0.1 2e-17 63.6 0.0 2.6 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KII94179.1 - 9.7e-06 25.6 1.2 2.4e-05 24.3 1.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain MRP-S25 PF13741.6 KII94180.1 - 2.5e-50 171.2 6.0 4.5e-49 167.1 6.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KII94180.1 - 0.028 14.7 1.7 0.11 12.7 1.7 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 SF3A2 PF16835.5 KII94181.1 - 2.8e-37 127.0 0.2 4.1e-37 126.4 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KII94181.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KII94181.1 - 0.0083 15.7 0.9 0.016 14.7 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KII94181.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein S1 PF00575.23 KII94182.1 - 3.1e-55 184.4 23.2 4.2e-12 46.2 0.2 10.6 10 0 0 10 10 10 10 S1 RNA binding domain TPR_16 PF13432.6 KII94182.1 - 1.1e-05 25.9 0.0 0.021 15.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII94182.1 - 2e-05 24.8 2.0 0.16 12.3 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII94182.1 - 3.4e-05 24.3 0.0 8.2 7.5 0.0 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KII94182.1 - 3.8e-05 23.0 4.3 0.0049 16.0 2.2 3.4 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KII94182.1 - 0.00014 22.3 0.0 0.28 11.7 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KII94182.1 - 0.00025 21.2 0.1 0.00075 19.7 0.1 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KII94182.1 - 0.00072 19.3 0.1 0.0014 18.4 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain Suf PF05843.14 KII94182.1 - 0.0036 17.3 0.0 0.0036 17.3 0.0 4.0 2 1 2 5 5 5 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 KII94182.1 - 0.0039 17.1 2.5 0.47 10.4 0.1 4.4 3 0 0 3 3 3 1 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 KII94182.1 - 0.005 16.9 0.6 9.1 6.4 0.0 4.9 4 0 0 4 4 4 1 S1 domain DUF2110 PF09883.9 KII94182.1 - 0.0071 16.0 2.3 0.065 12.8 0.1 3.4 4 1 1 5 5 5 1 Uncharacterized protein conserved in archaea (DUF2110) TPR_15 PF13429.6 KII94182.1 - 0.032 13.4 1.1 0.84 8.8 0.1 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII94182.1 - 0.059 14.0 0.0 14 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KII94182.1 - 0.099 12.8 2.0 14 6.1 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KII94182.1 - 0.18 12.1 0.2 17 5.9 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Kelch_3 PF13415.6 KII94183.1 - 1.9e-36 123.7 6.9 1.1e-07 32.0 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KII94183.1 - 1.4e-30 105.1 13.0 8e-08 32.2 0.2 6.5 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KII94183.1 - 1.2e-29 101.6 2.8 6.6e-08 32.6 0.2 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KII94183.1 - 4.3e-28 96.8 2.4 5.7e-06 26.2 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KII94183.1 - 2e-27 94.5 0.9 3.2e-05 23.4 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KII94183.1 - 2.4e-22 78.0 12.3 0.0015 18.4 0.2 6.7 6 1 0 6 6 6 5 Kelch motif Fez1 PF06818.15 KII94183.1 - 0.0068 16.9 18.8 0.0068 16.9 18.8 6.1 2 1 3 5 5 5 2 Fez1 Streptin-Immun PF11083.8 KII94183.1 - 0.12 12.8 3.7 0.42 11.0 0.3 3.5 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein Esterase PF00756.20 KII94185.1 - 3.9e-40 138.1 0.0 4.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KII94185.1 - 0.0026 16.7 0.0 0.0044 16.0 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KII94185.1 - 0.026 15.1 0.0 0.03 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII94185.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 KII94186.1 - 1.1e-51 175.8 0.0 1.9e-51 174.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94186.1 - 5e-30 104.7 0.0 7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII94186.1 - 0.00017 21.0 0.0 0.00045 19.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FHA PF00498.26 KII94186.1 - 0.0093 16.3 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 KII94186.1 - 0.016 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KII94186.1 - 0.062 12.6 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.23 KII94187.1 - 2.8e-15 56.4 0.1 2.8e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII94187.1 - 7.1e-07 29.3 0.1 0.004 17.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KII94187.1 - 3.4e-05 23.4 0.1 0.00016 21.2 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 KII94187.1 - 0.00087 18.7 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 AIG1 family cobW PF02492.19 KII94187.1 - 0.092 12.3 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CDC45 PF02724.14 KII94187.1 - 0.51 8.6 8.1 0.91 7.7 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Dynamin_N PF00350.23 KII94187.1 - 1.2 9.1 5.8 0.17 11.9 0.7 2.1 2 1 1 3 3 3 0 Dynamin family DUF4692 PF15763.5 KII94187.1 - 2.6 8.5 5.4 6.2 7.3 5.4 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Cellulase PF00150.18 KII94188.1 - 1.1e-45 156.2 0.0 1.3e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1759 PF03564.15 KII94188.1 - 0.19 11.6 0.0 0.53 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4817 PF16087.5 KII94189.1 - 0.056 13.3 0.1 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HNH_2 PF13391.6 KII94191.1 - 0.017 15.2 0.1 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease RunxI PF08504.11 KII94191.1 - 0.18 12.5 3.5 0.67 10.7 3.2 2.0 2 0 0 2 2 2 0 Runx inhibition domain CCDC24 PF15669.5 KII94191.1 - 0.85 9.4 3.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Methyltransf_25 PF13649.6 KII94192.1 - 4e-08 33.9 0.0 8.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII94192.1 - 7.8e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII94192.1 - 1.3e-05 25.7 0.0 3e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII94192.1 - 0.00027 21.6 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII94192.1 - 0.00066 19.5 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KII94192.1 - 0.016 14.7 0.0 0.071 12.6 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.15 KII94192.1 - 0.23 11.3 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase DNA_pol_B_palm PF14792.6 KII94194.1 - 6.4e-27 94.0 0.0 2.5e-26 92.1 0.0 2.0 3 0 0 3 3 3 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KII94194.1 - 2.1e-21 75.5 0.6 3.9e-20 71.4 0.2 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KII94194.1 - 2.8e-20 72.2 0.0 7.3e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KII94194.1 - 8e-18 64.6 0.2 3.6e-17 62.5 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KII94194.1 - 0.011 16.4 0.5 1.3 9.6 0.1 2.9 3 0 0 3 3 2 0 Helix-hairpin-helix domain Tub_N PF16322.5 KII94194.1 - 0.055 13.9 2.2 0.092 13.1 2.2 1.3 1 0 0 1 1 1 0 Tubby N-terminal HHH PF00633.23 KII94194.1 - 0.086 12.7 0.4 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3701 PF12482.8 KII94194.1 - 0.12 12.4 0.1 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 Phage integrase protein BRCT PF00533.26 KII94194.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KII94194.1 - 0.16 12.4 0.2 4.8 7.7 0.0 3.0 3 0 0 3 3 3 0 IMS family HHH motif NTP_transf_2 PF01909.23 KII94194.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cellulase PF00150.18 KII94195.1 - 4.4e-49 167.4 0.0 5.4e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KII94195.1 - 1.6e-13 50.3 7.7 4.5e-13 48.9 7.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Complex1_LYR PF05347.15 KII94196.1 - 0.00039 20.4 5.9 0.00078 19.4 5.9 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Sec8_exocyst PF04048.14 KII94197.1 - 3.6e-35 120.9 0.7 7.8e-35 119.8 0.7 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KII94197.1 - 8.6e-06 25.2 0.5 8.6e-06 25.2 0.5 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex LIDHydrolase PF10230.9 KII94198.1 - 1.2e-45 156.2 0.0 1.4e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KII94198.1 - 6.7e-06 26.9 2.2 1e-05 26.2 2.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII94198.1 - 0.0004 19.7 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 KII94198.1 - 0.03 13.8 0.4 0.78 9.2 0.1 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 KII94198.1 - 0.056 13.2 0.2 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein SNF2_N PF00176.23 KII94199.1 - 8.4e-58 195.7 0.6 1.4e-57 195.0 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII94199.1 - 4.5e-18 65.6 0.0 1.2e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KII94199.1 - 1.4e-17 63.9 0.2 2.7e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 KII94199.1 - 8.9e-10 38.4 4.4 4.1e-06 26.5 0.1 3.2 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KII94199.1 - 2.7e-05 24.3 0.0 7.7e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KII94199.1 - 0.00062 19.0 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Chromo PF00385.24 KII94199.1 - 0.0023 17.8 7.5 0.053 13.4 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain UPF0014 PF03649.13 KII94200.1 - 3.9e-71 239.2 17.2 5.6e-71 238.7 17.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) S4 PF01479.25 KII94201.1 - 1.2e-11 44.1 0.8 1.2e-11 44.1 0.8 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KII94201.1 - 9.7e-07 29.6 0.1 1.7e-06 28.9 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KII94202.1 - 1.1e-45 153.6 3.0 1.8e-45 152.9 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 KII94202.1 - 0.085 12.3 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Surface antigen Lipase_GDSL_2 PF13472.6 KII94203.1 - 1.1e-12 48.7 0.0 1.5e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII94203.1 - 0.00015 21.8 0.1 0.0034 17.4 0.1 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GRDP-like PF07173.12 KII94204.1 - 1.1e-20 74.7 0.2 1.3e-16 61.6 0.0 3.1 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like Zn_Tnp_IS1595 PF12760.7 KII94204.1 - 0.076 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TIP49 PF06068.13 KII94207.1 - 9.1e-157 521.7 0.6 1.3e-156 521.3 0.6 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KII94207.1 - 2.2e-21 75.8 1.5 7.7e-21 74.0 0.7 2.3 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KII94207.1 - 6.1e-09 36.4 0.3 1.1e-05 25.9 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KII94207.1 - 1.9e-06 27.7 0.2 0.0035 17.1 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KII94207.1 - 2.1e-05 24.0 0.5 4.2e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KII94207.1 - 0.00019 21.8 0.1 0.00084 19.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KII94207.1 - 0.0027 17.1 2.3 0.054 12.9 0.4 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KII94207.1 - 0.0048 17.2 0.0 0.25 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KII94207.1 - 0.014 15.3 0.2 6.8 6.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KII94207.1 - 0.028 14.7 3.4 0.096 13.0 1.3 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KII94207.1 - 0.038 13.6 0.1 0.091 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain ThrE PF06738.12 KII94210.1 - 4.2e-46 157.3 8.6 4.2e-46 157.3 8.6 2.4 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KII94210.1 - 5.6e-09 36.2 7.6 5.6e-09 36.2 7.6 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE SNF2_N PF00176.23 KII94211.1 - 1.9e-69 234.0 0.0 2.7e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII94211.1 - 2.3e-14 53.7 0.0 5.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KII94211.1 - 0.00011 22.1 2.1 0.00024 21.0 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII94211.1 - 0.011 15.6 2.7 0.032 14.1 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KII94211.1 - 0.015 15.4 0.0 0.63 10.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KII94211.1 - 0.18 11.7 1.7 0.46 10.4 1.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII94211.1 - 0.29 11.0 2.6 0.65 9.9 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 dsrm PF00035.26 KII94212.1 - 2.5e-08 34.5 0.1 5.9e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 KII94212.1 - 3.9e-07 30.3 0.0 6.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII94212.1 - 0.014 16.0 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain MARVEL PF01284.23 KII94213.1 - 1.8e-07 31.3 9.5 2.5e-07 30.8 9.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.9 KII94213.1 - 0.0059 16.2 3.0 0.0059 16.2 3.0 1.9 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family LysM PF01476.20 KII94214.1 - 5.4e-10 39.2 0.0 7.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain Ferlin_C PF16165.5 KII94214.1 - 0.24 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Malic_M PF03949.15 KII94215.1 - 1.6e-82 276.7 0.0 2.1e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KII94215.1 - 7.9e-62 208.3 0.0 1.1e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RapH_N PF18801.1 KII94215.1 - 0.092 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal NTP_transf_2 PF01909.23 KII94216.1 - 3.7e-05 24.0 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KII94216.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 KII94216.1 - 0.0025 18.0 0.5 0.0047 17.1 0.5 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase AXIN1_TNKS_BD PF16646.5 KII94217.1 - 0.0031 18.4 1.3 0.0031 18.4 1.3 1.5 2 0 0 2 2 2 1 Axin-1 tankyrase binding domain PAP_assoc PF03828.19 KII94218.1 - 2.6e-08 34.0 0.0 5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Ribosomal_L28e PF01778.17 KII94219.1 - 3.8e-30 105.0 0.0 4.9e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family F-box PF00646.33 KII94220.1 - 0.00021 21.1 0.5 0.00066 19.5 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII94220.1 - 0.00034 20.4 0.1 0.0017 18.2 0.1 2.3 1 0 0 1 1 1 1 F-box-like S6PP_C PF08472.10 KII94220.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal HAP2-GCS1 PF10699.9 KII94220.1 - 2.8 8.0 5.3 0.41 10.7 0.8 2.0 2 0 0 2 2 2 0 Male gamete fusion factor F-box PF00646.33 KII94221.1 - 0.00046 20.0 0.8 0.0014 18.5 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII94221.1 - 0.013 15.3 0.2 0.013 15.3 0.2 2.5 4 0 0 4 4 4 0 F-box-like RRM_1 PF00076.22 KII94222.1 - 2.2e-25 88.3 0.1 1.1e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94222.1 - 6.3e-14 51.7 0.0 1.4e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII94222.1 - 3.5e-08 33.2 0.0 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KII94222.1 - 0.013 15.6 0.1 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 Limkain b1 BTB_2 PF02214.22 KII94223.1 - 0.00026 21.3 0.0 0.0034 17.7 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain ACOX PF01756.19 KII94224.1 - 2.9e-37 128.0 0.0 6.3e-37 126.9 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KII94224.1 - 8.3e-12 45.7 0.0 1.6e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KII94224.1 - 0.00023 21.3 0.0 0.00059 20.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KII94224.1 - 0.0015 18.7 0.7 0.0032 17.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain RNA_ligase PF09414.10 KII94225.1 - 1.2e-27 97.2 0.0 1.8e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 KII94225.1 - 4.4e-12 46.4 0.0 1.7e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain Y_phosphatase PF00102.27 KII94225.1 - 5.5e-07 29.4 0.0 9.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KII94225.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KII94225.1 - 0.00027 20.6 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 KII94225.1 - 0.00099 18.8 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 KII94225.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 KII94225.1 - 0.0021 17.9 0.0 0.0054 16.5 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AAA_22 PF13401.6 KII94225.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PfkB PF00294.24 KII94226.1 - 3.2e-69 233.5 0.8 3.6e-69 233.4 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KII94226.1 - 0.029 13.7 0.0 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase DEC-1_C PF04626.13 KII94226.1 - 0.034 14.6 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-C2H2 PF00096.26 KII94227.1 - 8.5e-09 35.4 4.4 0.0011 19.3 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII94227.1 - 1.2e-07 31.9 2.4 0.0008 20.0 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII94227.1 - 0.00011 22.4 1.6 0.048 14.0 0.6 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KII94227.1 - 0.0019 18.2 1.5 0.013 15.5 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger Sugarporin_N PF11471.8 KII94227.1 - 0.026 14.5 1.1 0.05 13.6 1.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension zf-met PF12874.7 KII94227.1 - 0.043 14.2 0.4 0.54 10.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KII94227.1 - 0.051 14.0 0.4 0.051 14.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 KII94227.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 KII94227.1 - 0.092 12.6 1.1 0.19 11.5 1.1 1.5 1 0 0 1 1 1 0 GAGA factor zf-RRN7 PF11781.8 KII94227.1 - 0.71 9.6 2.1 17 5.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 YdjO PF14169.6 KII94227.1 - 1.4 8.7 4.2 5.3 6.9 4.2 1.9 1 1 0 1 1 1 0 Cold-inducible protein YdjO Raptor_N PF14538.6 KII94228.1 - 7.6e-61 204.4 0.0 1.5e-60 203.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 KII94228.1 - 2e-05 24.5 0.5 0.00073 19.6 0.0 3.4 4 0 0 4 4 4 1 HEAT repeat WD40 PF00400.32 KII94228.1 - 4.9e-05 24.0 3.0 0.11 13.4 0.3 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT_EZ PF13513.6 KII94228.1 - 0.00037 20.9 0.1 0.004 17.6 0.0 2.8 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 KII94228.1 - 0.0011 19.3 0.0 0.0065 16.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats BBS2_Mid PF14783.6 KII94228.1 - 0.2 11.7 0.3 0.9 9.6 0.0 2.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Dynactin PF12455.8 KII94229.1 - 2e-95 319.3 3.6 2e-95 319.3 3.6 4.4 4 2 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 KII94229.1 - 1.1e-22 79.8 0.6 3.3e-22 78.3 0.6 1.8 2 0 0 2 2 2 1 CAP-Gly domain F_actin_bind PF08919.10 KII94229.1 - 10 6.3 10.2 1.1 9.4 2.3 3.6 3 0 0 3 3 3 0 F-actin binding RCC1 PF00415.18 KII94230.1 - 1.1e-24 86.8 15.6 2.7e-05 24.7 0.4 8.0 7 2 1 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII94230.1 - 7.2e-12 44.8 26.7 0.0054 16.5 0.0 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RdRP PF05183.12 KII94231.1 - 1.4e-90 304.7 0.0 1.8e-90 304.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Mtd_N PF18454.1 KII94231.1 - 0.013 15.5 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain Chitin_synth_2 PF03142.15 KII94232.1 - 4.4e-278 923.2 0.0 5.6e-278 922.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KII94232.1 - 1.6e-10 41.3 2.4 6.1e-10 39.3 2.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KII94232.1 - 7.6e-10 39.1 0.0 8.2e-09 35.7 0.0 2.2 1 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KII94232.1 - 0.0015 18.0 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KII94232.1 - 0.061 13.1 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Nop10p PF04135.12 KII94233.1 - 1.7e-22 79.2 0.2 1.9e-22 79.0 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pyridox_oxase_2 PF12766.7 KII94235.1 - 6.5e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KII94235.1 - 7.6e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CorA PF01544.18 KII94236.1 - 6.2e-35 120.9 9.1 7e-30 104.3 8.2 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Thioredoxin PF00085.20 KII94237.1 - 2e-23 82.3 0.0 2.3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KII94237.1 - 2.7e-05 24.6 0.0 0.00013 22.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KII94237.1 - 0.00025 20.9 0.0 0.00032 20.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KII94237.1 - 0.00061 20.1 0.0 0.0027 18.0 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 KII94237.1 - 0.0017 17.8 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KII94237.1 - 0.0057 16.4 0.0 0.008 16.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KII94237.1 - 0.0078 15.9 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 KII94237.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 KII94238.1 - 3.5e-26 91.2 0.0 4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KII94238.1 - 1.4e-07 32.0 0.1 5.2e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KII94238.1 - 4.2e-06 27.0 0.0 6.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KII94238.1 - 5e-06 26.3 0.0 5.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KII94238.1 - 5e-06 26.4 0.0 5.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII94238.1 - 2.2e-05 24.2 0.1 6.3e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 KII94238.1 - 0.002 17.6 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 KII94238.1 - 0.0033 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 KII94238.1 - 0.042 14.0 0.1 0.05 13.8 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like DUF2847 PF11009.8 KII94238.1 - 0.19 11.7 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DUF4131 PF13567.6 KII94239.1 - 0.12 12.0 1.4 0.12 12.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 KII94242.1 - 1.5e-60 204.8 0.0 5.9e-36 124.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII94242.1 - 2e-25 89.6 0.0 8.8e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KII94242.1 - 0.00058 20.5 8.3 0.00058 20.5 8.3 3.7 4 0 0 4 4 4 1 Protein kinase C terminal domain PX PF00787.24 KII94242.1 - 0.0021 18.0 0.0 0.0062 16.5 0.0 1.8 1 1 0 1 1 1 1 PX domain FTA2 PF13095.6 KII94242.1 - 0.0023 17.6 0.1 0.44 10.1 0.1 2.7 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KII94242.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII94242.1 - 0.021 14.8 0.4 5.5 6.8 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KII94242.1 - 0.14 11.5 0.0 4.1 6.6 0.0 2.5 3 0 0 3 3 3 0 Kinase-like VASt PF16016.5 KII94243.1 - 1.4e-39 135.9 0.0 2.8e-39 135.0 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KII94243.1 - 1.4e-23 83.0 0.0 2.5e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Plasmodium_Vir PF05795.11 KII94243.1 - 3.5 7.0 3.9 29 4.0 4.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein ABC_tran PF00005.27 KII94244.1 - 3.5e-50 170.1 0.0 1.3e-23 84.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KII94244.1 - 2.4e-23 82.8 44.0 1.5e-13 50.6 21.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KII94244.1 - 2.6e-19 70.1 1.9 2.1e-05 24.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KII94244.1 - 4.3e-06 27.3 0.0 0.026 15.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) ABC2_membrane PF01061.24 KII94244.1 - 6.6e-06 25.7 11.3 6.6e-06 25.7 11.3 4.2 4 0 0 4 4 4 2 ABC-2 type transporter AAA_23 PF13476.6 KII94244.1 - 4.5e-05 24.1 3.2 0.011 16.3 0.8 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII94244.1 - 0.00018 21.2 2.1 0.061 13.1 0.6 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KII94244.1 - 0.00047 19.7 3.0 6.3 6.2 0.3 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KII94244.1 - 0.0027 17.5 0.7 0.75 9.5 0.0 3.5 3 1 1 4 4 4 1 AAA domain AAA_27 PF13514.6 KII94244.1 - 0.0062 16.1 0.3 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KII94244.1 - 0.0094 15.7 0.0 1.1 8.9 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KII94244.1 - 0.055 13.4 0.8 6.3 6.7 0.4 2.3 2 0 0 2 2 2 0 RsgA GTPase MukB PF04310.12 KII94244.1 - 0.12 12.2 0.3 15 5.3 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal TMEM135_C_rich PF15982.5 KII94245.1 - 6e-06 26.9 1.3 4.4e-05 24.1 1.3 2.4 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Yae1_N PF09811.9 KII94246.1 - 4.2e-10 39.2 4.0 6.5e-10 38.6 4.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.20 KII94247.1 - 5.4e-157 522.9 0.0 6.6e-157 522.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KII94247.1 - 3.4e-14 53.1 0.0 6.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KII94247.1 - 0.00025 21.2 0.0 0.00048 20.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_9 PF13371.6 KII94248.1 - 0.00048 20.2 2.0 0.0012 18.9 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Pollen_allerg_1 PF01357.21 KII94249.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Pollen allergen zf-C2H2 PF00096.26 KII94250.1 - 1.1e-09 38.2 13.2 2.7e-05 24.4 2.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII94250.1 - 9.7e-05 22.6 6.0 9.7e-05 22.6 6.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII94250.1 - 0.00065 20.3 12.3 0.11 13.4 2.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KII94250.1 - 0.0027 18.0 1.4 0.0053 17.0 1.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KII94250.1 - 0.041 14.5 6.5 0.23 12.1 0.4 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KII94252.1 - 4.9e-11 42.4 9.8 3.3e-05 24.1 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII94252.1 - 6.1e-06 26.6 9.8 0.0032 18.2 1.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII94252.1 - 0.00014 22.2 4.7 0.00014 22.2 4.7 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KII94252.1 - 0.031 14.3 1.5 0.031 14.3 1.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KII94252.1 - 0.086 13.5 4.0 1.2 9.9 0.5 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KII94252.1 - 1.3 8.9 8.8 0.47 10.3 1.5 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 KII94252.1 - 2.5 7.9 14.7 0.87 9.4 1.8 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 KII94252.1 - 2.6 8.1 5.0 11 6.2 0.5 1.9 1 1 1 2 2 2 0 Aberrant zinc-finger zf-BED PF02892.15 KII94252.1 - 3.7 7.6 7.2 13 5.9 0.7 2.4 2 0 0 2 2 2 0 BED zinc finger EF-hand_7 PF13499.6 KII94254.1 - 8.7e-25 87.0 14.3 5.2e-14 52.4 5.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KII94254.1 - 1.3e-24 83.9 17.5 1.4e-09 36.8 0.3 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KII94254.1 - 2.8e-19 67.3 15.3 1e-08 34.4 0.2 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 KII94254.1 - 3.9e-15 55.4 16.6 2e-09 37.2 1.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 KII94254.1 - 1.5e-12 46.4 9.4 1.9e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 KII94254.1 - 1.4e-10 41.3 1.9 0.0004 20.7 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KII94254.1 - 5.2e-08 32.8 5.2 0.00071 19.5 0.2 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KII94254.1 - 0.00019 21.4 2.8 0.01 15.8 0.1 3.0 1 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 KII94254.1 - 0.0047 17.2 4.2 0.3 11.4 0.3 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 KII94254.1 - 0.0085 16.1 3.4 0.58 10.1 0.2 2.4 3 0 0 3 3 3 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 KII94254.1 - 0.049 13.8 0.3 2.1 8.6 0.5 2.3 2 0 0 2 2 2 0 Dockerin type I domain SurA_N_2 PF13623.6 KII94254.1 - 0.05 13.5 3.0 3.4 7.5 0.4 2.4 2 1 0 2 2 2 0 SurA N-terminal domain DUF4834 PF16118.5 KII94254.1 - 0.072 14.1 0.6 0.15 13.1 0.4 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) EF-hand_14 PF17959.1 KII94254.1 - 0.086 13.2 2.6 0.56 10.6 0.4 2.4 2 1 0 2 2 2 0 EF-hand domain EF-hand_11 PF08976.11 KII94254.1 - 0.16 12.8 1.0 13 6.8 0.2 2.2 1 1 1 2 2 2 0 EF-hand domain Com_YlbF PF06133.11 KII94254.1 - 0.82 10.3 6.5 11 6.7 0.8 2.6 2 2 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA zf-C2H2 PF00096.26 KII94255.1 - 4.2e-14 52.1 42.4 0.014 15.8 0.3 8.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-met PF12874.7 KII94255.1 - 9.5e-12 44.9 28.9 0.002 18.5 0.8 7.4 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KII94255.1 - 1.5e-11 44.1 40.5 0.15 13.0 0.5 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KII94255.1 - 2e-10 40.7 31.0 0.00018 21.7 2.8 6.4 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KII94255.1 - 2.9e-05 24.3 29.2 0.0026 18.0 12.1 4.3 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KII94255.1 - 0.00034 20.5 31.6 0.0015 18.5 0.8 6.1 6 1 1 7 7 7 3 C2H2-type zinc finger DUF4187 PF13821.6 KII94255.1 - 0.0019 17.9 14.0 0.019 14.7 0.2 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF4187) zf_UBZ PF18439.1 KII94255.1 - 0.0086 15.7 26.1 0.059 13.0 0.4 5.5 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 KII94255.1 - 0.013 15.3 12.8 0.19 11.5 3.0 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KII94255.1 - 0.13 12.2 16.5 13 5.7 0.0 5.9 3 2 2 6 6 6 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 KII94255.1 - 1.3 9.7 21.8 0.41 11.3 2.0 4.2 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Swi5 PF07061.11 KII94256.1 - 3.2e-20 72.0 1.7 3.4e-20 71.9 1.7 1.0 1 0 0 1 1 1 1 Swi5 Macoilin PF09726.9 KII94256.1 - 0.0054 15.4 0.4 0.0056 15.3 0.4 1.0 1 0 0 1 1 1 1 Macoilin family ABC_tran_CTD PF16326.5 KII94256.1 - 0.02 15.1 1.3 0.027 14.7 1.3 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Mito_carr PF00153.27 KII94257.1 - 1.4e-50 169.2 0.7 4.7e-18 64.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.15 KII94258.1 - 3.4e-48 164.0 0.1 1.5e-47 161.9 0.1 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KII94258.1 - 6.8e-30 103.9 1.4 1.6e-29 102.7 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KII94258.1 - 2.1e-18 66.4 0.0 6.6e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KII94258.1 - 5.2e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain ZapD PF07072.11 KII94258.1 - 0.055 13.2 0.2 0.17 11.6 0.2 1.8 1 0 0 1 1 1 0 Cell division protein Nucleo_P87 PF07267.11 KII94258.1 - 2.3 6.9 6.9 4.1 6.1 6.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Gcd10p PF04189.13 KII94259.1 - 9.4e-68 228.5 0.0 1.5e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family HlyD_D4 PF16572.5 KII94259.1 - 0.089 12.7 0.2 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB GCM PF03615.15 KII94260.1 - 0.0042 17.0 1.1 0.0083 16.0 1.1 1.5 1 0 0 1 1 1 1 GCM motif protein Rab_bind PF16704.5 KII94260.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Rab binding domain zf-MYND PF01753.18 KII94262.1 - 0.071 13.2 0.8 0.071 13.2 0.8 2.1 2 0 0 2 2 2 0 MYND finger UNC45-central PF11701.8 KII94263.1 - 1.8e-31 109.2 1.8 5.5e-31 107.6 0.0 2.6 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Myosin_head PF00063.21 KII94264.1 - 1.1e-237 790.5 0.2 1.4e-237 790.3 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KII94264.1 - 1.1e-51 175.2 0.0 2.2e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_2 PF07653.17 KII94264.1 - 5.3e-10 38.8 0.0 1.4e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KII94264.1 - 9.5e-10 38.2 0.1 2e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII94264.1 - 6.8e-09 35.2 1.0 1.3e-08 34.3 1.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 KII94264.1 - 0.00016 21.9 0.1 0.00036 20.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_16 PF13191.6 KII94264.1 - 0.057 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KII94264.1 - 0.063 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SH3_4 PF06347.13 KII94264.1 - 0.081 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Hpr_kinase_C PF07475.12 KII94264.1 - 0.11 12.0 1.0 8 6.0 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 KII94264.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Lum_binding PF00677.17 KII94266.1 - 7.9e-40 134.7 0.0 4.3e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF1860 PF08949.10 KII94266.1 - 0.07 12.9 0.3 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) DAO PF01266.24 KII94267.1 - 6.2e-29 101.7 1.6 8.1e-29 101.3 1.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII94267.1 - 0.0085 16.3 0.1 0.026 14.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KII94267.1 - 0.035 14.7 0.3 0.079 13.5 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KII94267.1 - 0.062 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KII94267.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-RING_2 PF13639.6 KII94268.1 - 6.8e-11 42.3 4.8 6.8e-11 42.3 4.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KII94268.1 - 1.1e-09 38.4 3.6 1.1e-09 38.4 3.6 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KII94268.1 - 5.5e-07 29.3 6.4 5.5e-07 29.3 6.4 2.4 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII94268.1 - 1.6e-06 28.0 2.1 1.6e-06 28.0 2.1 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KII94268.1 - 1.7e-06 27.8 3.9 1.7e-06 27.8 3.9 2.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII94268.1 - 1.9e-06 27.7 3.3 1.9e-06 27.7 3.3 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KII94268.1 - 1e-05 25.5 0.6 2.2e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KII94268.1 - 4.9e-05 23.0 3.9 4.9e-05 23.0 3.9 2.1 2 1 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KII94268.1 - 0.0002 21.1 9.9 0.00021 21.1 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KII94268.1 - 0.00021 21.5 5.4 0.00028 21.1 2.4 2.4 2 0 0 2 2 2 1 zinc-ribbon Prok-RING_4 PF14447.6 KII94268.1 - 0.0015 18.3 5.3 0.0015 18.3 5.3 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 KII94268.1 - 0.0061 16.7 3.4 0.052 13.7 3.4 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain HypA PF01155.19 KII94268.1 - 0.58 10.2 5.4 4.9 7.2 0.4 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KII94268.1 - 1.7 8.7 7.5 12 6.0 0.6 3.0 2 1 0 3 3 3 0 Double zinc ribbon PHD PF00628.29 KII94268.1 - 4.8 7.2 14.9 0.34 10.8 4.2 2.8 3 0 0 3 3 3 0 PHD-finger ABC_tran PF00005.27 KII94269.1 - 1.3e-51 174.7 0.0 8.4e-30 104.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KII94269.1 - 4e-51 174.3 15.9 1.5e-32 113.3 1.8 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KII94269.1 - 8.7e-09 35.1 4.2 0.0012 18.4 0.3 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KII94269.1 - 5.7e-08 32.1 1.5 0.0094 15.0 0.0 2.8 2 1 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.6 KII94269.1 - 2.7e-07 30.2 0.3 0.032 14.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KII94269.1 - 3.4e-07 30.8 1.3 0.0089 16.4 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KII94269.1 - 8.2e-06 26.5 0.7 0.0027 18.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII94269.1 - 1.8e-05 24.4 0.1 0.21 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KII94269.1 - 4.2e-05 23.8 0.4 0.31 11.3 0.3 3.0 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 KII94269.1 - 5.4e-05 23.4 0.6 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KII94269.1 - 8.1e-05 22.1 0.0 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 KII94269.1 - 0.00015 21.1 0.1 0.037 13.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin TrwB_AAD_bind PF10412.9 KII94269.1 - 0.00033 19.7 0.0 0.26 10.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KII94269.1 - 0.0011 18.9 0.2 1 9.2 0.1 2.7 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KII94269.1 - 0.0012 18.5 0.5 0.16 11.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KII94269.1 - 0.0012 18.7 0.1 0.95 9.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase CbiA PF01656.23 KII94269.1 - 0.0014 18.7 0.0 0.77 9.8 0.0 2.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 KII94269.1 - 0.0026 17.8 0.2 0.34 11.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KII94269.1 - 0.0034 16.9 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2075 PF09848.9 KII94269.1 - 0.0035 16.6 0.3 0.35 10.1 0.0 2.6 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KII94269.1 - 0.0041 16.9 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA PF00004.29 KII94269.1 - 0.0048 17.3 2.0 9.1 6.7 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KII94269.1 - 0.0051 16.5 0.3 4.7 6.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KII94269.1 - 0.0081 15.7 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein ATPase PF06745.13 KII94269.1 - 0.012 14.9 0.2 0.91 8.8 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.6 KII94269.1 - 0.014 15.5 0.3 3.1 7.9 0.2 2.8 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KII94269.1 - 0.024 14.4 2.0 10 5.8 0.9 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KII94269.1 - 0.048 13.7 0.7 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family MobB PF03205.14 KII94269.1 - 0.084 12.8 0.2 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 KII94269.1 - 0.096 13.2 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KII94269.1 - 0.13 12.0 3.1 26 4.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KII94269.1 - 0.14 11.3 0.3 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KII94269.1 - 0.14 11.8 0.0 8.8 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KII94269.1 - 0.16 12.4 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 KII94269.1 - 0.19 11.5 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KII94269.1 - 0.21 11.6 0.1 26 4.8 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit RTA1 PF04479.13 KII94270.1 - 1.7e-57 194.4 9.4 2.2e-57 194.0 9.4 1.1 1 0 0 1 1 1 1 RTA1 like protein PetG PF02529.15 KII94270.1 - 0.067 13.1 0.7 0.17 11.8 0.7 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF89 PF01937.19 KII94275.1 - 8.5e-107 357.2 0.1 1e-106 356.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CC2-LZ PF16516.5 KII94276.1 - 0.00033 21.0 11.1 0.00033 21.0 11.1 15.0 9 5 3 15 15 15 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GAS PF13851.6 KII94276.1 - 0.00036 19.9 10.8 0.00036 19.9 10.8 11.8 5 3 5 11 11 11 3 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 KII94276.1 - 0.36 10.7 0.0 0.36 10.7 0.0 10.3 12 0 0 12 12 12 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lgl_C PF08596.10 KII94277.1 - 8.3e-35 120.2 0.0 3.3e-34 118.2 0.0 2.0 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KII94277.1 - 0.00048 20.9 1.4 0.18 12.7 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94277.1 - 0.0062 16.8 0.0 0.75 10.1 0.0 3.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hepar_II_III PF07940.13 KII94278.1 - 2e-07 30.9 0.2 3.6e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein FAM70 PF14967.6 KII94278.1 - 0.16 11.4 1.0 0.3 10.5 1.0 1.4 1 0 0 1 1 1 0 FAM70 protein Rick_17kDa_Anti PF05433.15 KII94278.1 - 0.3 11.0 6.7 0.64 9.9 6.7 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain cEGF PF12662.7 KII94279.1 - 0.003 17.4 0.5 0.003 17.4 0.5 2.8 4 0 0 4 4 4 1 Complement Clr-like EGF-like Retrotran_gag_2 PF14223.6 KII94280.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KII94280.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NPBW PF15180.6 KII94285.1 - 0.62 9.9 4.2 0.39 10.6 1.1 2.1 2 0 0 2 2 2 0 Neuropeptides B and W zf-C2H2_jaz PF12171.8 KII94286.1 - 1.1e-15 57.4 12.1 0.00032 20.9 0.1 6.4 5 1 2 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KII94286.1 - 4.2e-13 49.0 36.1 0.022 15.2 0.1 8.0 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII94286.1 - 1.1e-12 47.6 38.2 0.022 15.6 0.4 8.3 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.7 KII94286.1 - 6.7e-12 45.4 22.9 0.058 13.8 0.3 8.2 8 1 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KII94286.1 - 1.1e-09 38.1 23.4 1.2e-05 25.1 1.2 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KII94286.1 - 0.0019 18.5 27.6 0.59 10.5 5.4 5.1 2 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 KII94286.1 - 0.0024 17.9 19.4 0.57 10.3 0.2 6.3 4 1 3 7 7 7 2 Zic proteins zinc finger domain zf-trcl PF13451.6 KII94286.1 - 0.021 14.7 2.9 0.021 14.7 2.9 4.9 5 1 0 5 5 5 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 KII94286.1 - 0.041 14.3 0.0 0.041 14.3 0.0 6.7 8 0 0 8 8 7 0 Zinc-finger double domain zf_UBZ PF18439.1 KII94286.1 - 0.12 12.0 17.4 2.6 7.7 0.2 5.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-SNAP50_C PF12251.8 KII94286.1 - 0.14 11.8 17.5 0.09 12.4 2.4 2.6 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_9 PF16293.5 KII94286.1 - 0.15 11.9 9.5 10 6.1 0.4 4.8 3 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_11 PF16622.5 KII94286.1 - 0.18 11.6 22.7 2.9 7.7 0.0 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-TFIIB PF13453.6 KII94286.1 - 1.3 8.4 0.0 1.3 8.4 0.0 3.3 3 1 0 3 3 3 0 Transcription factor zinc-finger zf-RING_14 PF17978.1 KII94286.1 - 8.5 6.9 10.4 19 5.7 5.5 3.1 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Peptidase_M16 PF00675.20 KII94287.1 - 8.8e-39 132.9 0.0 1.3e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KII94287.1 - 2.3e-33 115.8 0.0 1.2e-32 113.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain OTCace_N PF02729.21 KII94287.1 - 0.094 12.7 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain BRCA-2_OB1 PF09103.10 KII94288.1 - 3.3e-34 117.5 0.0 5.2e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KII94288.1 - 6.5e-07 29.2 0.1 1.1e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 BRCA2, helical DDE_Tnp_1_2 PF13586.6 KII94288.1 - 0.27 11.6 1.4 12 6.4 0.5 2.9 2 0 0 2 2 2 0 Transposase DDE domain Cellulase PF00150.18 KII94290.1 - 3.6e-12 46.3 4.0 9.7e-11 41.6 4.0 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) UDPGP PF01704.18 KII94291.1 - 4.9e-42 144.0 0.0 6.3e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KII94291.1 - 0.016 15.6 0.1 0.036 14.4 0.1 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.9 KII94292.1 - 7.7e-18 64.7 35.2 4.9e-10 39.1 18.3 2.6 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KII94292.1 - 1.9e-06 27.6 0.3 0.024 14.5 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KII94292.1 - 0.65 9.8 3.3 3.4 7.5 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin family PriA_C PF18074.1 KII94292.1 - 1.5 9.7 6.6 0.24 12.3 0.4 3.0 3 1 0 3 3 3 0 Primosomal protein N C-terminal domain DUF1664 PF07889.12 KII94292.1 - 4.9 7.2 12.7 0.4 10.7 6.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HIT PF01230.23 KII94295.1 - 1.5e-25 89.7 0.1 2.1e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KII94295.1 - 2.8e-07 31.0 0.0 3.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Monellin PF09200.10 KII94295.1 - 0.048 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Monellin DUF5134 PF17197.4 KII94296.1 - 0.014 15.3 0.9 0.024 14.6 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Intg_mem_TP0381 PF09529.10 KII94296.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) TauD PF02668.16 KII94299.1 - 9.2e-46 156.8 0.1 1.2e-45 156.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_47 PF01532.20 KII94300.1 - 9.7e-152 506.0 0.0 1.1e-151 505.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.23 KII94301.1 - 2.3e-10 40.8 0.2 6.6e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KII94301.1 - 0.018 15.2 6.0 0.03 14.5 6.0 1.4 1 0 0 1 1 1 0 AN1-like Zinc finger DUF2180 PF09947.9 KII94301.1 - 0.19 11.7 0.9 0.44 10.6 0.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Enolase_C PF00113.22 KII94303.1 - 8.8e-145 481.5 0.1 1.2e-144 481.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KII94303.1 - 1.4e-57 193.5 0.0 2.3e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KII94303.1 - 2.9e-09 36.8 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KII94303.1 - 0.00038 19.7 0.1 0.00089 18.5 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus NGP1NT PF08153.12 KII94304.1 - 1.9e-50 170.4 0.0 3.8e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KII94304.1 - 2.5e-18 66.2 0.1 2.6e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KII94304.1 - 1.8e-05 24.3 0.6 0.00016 21.2 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KII94304.1 - 2.7e-05 24.2 0.0 6.8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KII94304.1 - 0.00072 19.1 0.6 0.062 12.8 0.2 2.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KII94304.1 - 0.01 15.3 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family YbfN PF13982.6 KII94304.1 - 0.024 14.9 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 YbfN-like lipoprotein Nop14 PF04147.12 KII94304.1 - 0.05 11.8 14.1 0.071 11.3 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Roc PF08477.13 KII94304.1 - 0.12 12.6 0.1 24 5.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KII94304.1 - 0.31 11.1 5.5 3.7 7.6 0.1 3.7 3 1 1 4 4 4 0 Dynamin family CDC45 PF02724.14 KII94304.1 - 3.4 5.8 10.9 5.2 5.2 10.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S15 PF00312.22 KII94305.1 - 4.4e-25 87.7 0.2 7.5e-25 86.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 HEAT_EZ PF13513.6 KII94307.1 - 1.2e-06 28.8 5.1 3.4 8.3 0.0 7.2 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 KII94307.1 - 2.5e-05 24.6 1.6 0.0015 18.8 0.0 4.1 3 0 0 3 3 3 1 HEAT repeats IBN_N PF03810.19 KII94307.1 - 3e-05 23.8 3.4 0.44 10.5 0.5 4.7 5 1 0 5 5 5 2 Importin-beta N-terminal domain ParcG PF10274.9 KII94307.1 - 6.9e-05 23.0 0.1 0.41 10.8 0.0 3.5 3 0 0 3 3 3 2 Parkin co-regulated protein HEAT PF02985.22 KII94307.1 - 0.00014 21.9 1.1 0.022 15.0 0.0 4.9 6 0 0 6 6 3 1 HEAT repeat Adaptin_N PF01602.20 KII94307.1 - 0.0002 20.1 0.2 0.0014 17.2 0.1 2.4 3 0 0 3 3 3 1 Adaptin N terminal region Xpo1 PF08389.12 KII94307.1 - 0.0011 19.0 0.0 0.01 15.9 0.0 2.7 2 1 0 2 2 2 1 Exportin 1-like protein V-ATPase_H_N PF03224.14 KII94307.1 - 0.0012 18.2 0.3 0.076 12.3 0.1 2.4 2 0 0 2 2 2 1 V-ATPase subunit H Cse1 PF08506.10 KII94307.1 - 0.0028 16.6 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 Cse1 RIX1 PF08167.12 KII94307.1 - 0.0038 17.0 1.0 0.041 13.6 0.5 2.7 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 KII94307.1 - 0.0087 14.6 0.0 0.044 12.3 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cnd1 PF12717.7 KII94307.1 - 0.072 13.1 0.0 0.33 11.0 0.0 2.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 TRI5 PF06330.11 KII94309.1 - 3.5e-22 78.8 0.1 5.1e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) zf-CCCH_4 PF18044.1 KII94310.1 - 5.8e-07 29.2 8.9 2.7e-05 23.8 0.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger TPR_1 PF00515.28 KII94310.1 - 5.1e-06 26.1 6.7 4.7e-05 23.0 0.3 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII94310.1 - 7.3e-06 25.7 4.5 3.7e-05 23.5 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII94310.1 - 0.0001 22.1 0.3 0.0046 16.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII94310.1 - 0.00015 22.3 6.6 0.0039 17.9 0.2 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 KII94310.1 - 0.00021 21.5 0.9 0.00043 20.5 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 KII94310.1 - 0.00021 21.2 14.3 0.11 12.6 6.2 3.1 2 1 0 2 2 2 2 Zinc finger domain TPR_16 PF13432.6 KII94310.1 - 0.00023 21.7 5.6 0.00049 20.7 3.3 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KII94310.1 - 0.00049 19.7 0.9 0.014 15.0 0.1 3.4 4 0 0 4 4 4 1 TPR repeat Torus PF16131.5 KII94310.1 - 0.00058 20.5 8.7 0.21 12.3 2.0 2.7 1 1 1 2 2 2 2 Torus domain TPR_12 PF13424.6 KII94310.1 - 0.0013 19.0 1.7 0.0036 17.6 1.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII94310.1 - 0.0023 18.4 9.0 0.0025 18.3 1.4 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII94310.1 - 0.0038 17.3 2.3 0.021 15.0 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KII94310.1 - 0.008 16.5 4.7 0.85 10.1 0.3 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII94310.1 - 0.022 15.4 0.1 0.022 15.4 0.1 3.0 3 1 1 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KII94310.1 - 0.026 14.8 4.0 0.026 14.8 4.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCCH_2 PF14608.6 KII94310.1 - 0.05 14.1 10.0 0.11 13.0 2.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 KII94310.1 - 0.093 12.7 12.1 0.068 13.1 1.1 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) kleA_kleC PF17383.2 KII94310.1 - 0.1 12.9 6.0 0.26 11.6 6.0 1.7 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Fis1_TPR_C PF14853.6 KII94310.1 - 0.14 12.3 4.2 5.2 7.2 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FoP_duplication PF13865.6 KII94310.1 - 1.4 9.5 17.9 0.093 13.3 11.0 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 IMUP PF15761.5 KII94310.1 - 2 9.1 11.0 6.9 7.4 2.2 3.2 3 0 0 3 3 3 0 Immortalisation up-regulated protein DASH_Ask1 PF08655.10 KII94311.1 - 3.7e-10 39.5 0.0 6.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Lipase_GDSL PF00657.22 KII94312.1 - 0.0012 18.9 0.1 0.0016 18.4 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KII94312.1 - 0.21 12.0 2.2 0.35 11.3 2.2 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Sugar_tr PF00083.24 KII94314.1 - 2.5e-126 422.2 16.6 2.9e-126 422.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII94314.1 - 7.5e-19 67.8 42.0 4.2e-17 62.1 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mid2 PF04478.12 KII94316.1 - 0.061 13.2 0.1 0.061 13.2 0.1 3.6 3 2 1 4 4 4 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 KII94316.1 - 0.1 13.5 0.0 0.31 12.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KII94316.1 - 0.13 11.1 0.4 0.3 9.9 0.1 1.5 1 1 0 1 1 1 0 Amnionless SKG6 PF08693.10 KII94316.1 - 0.99 8.9 4.7 0.24 10.9 0.1 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain G-alpha PF00503.20 KII94317.1 - 3.7e-116 388.2 0.0 4.3e-116 387.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII94317.1 - 5.7e-15 55.2 0.1 7.5e-11 41.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KII94317.1 - 0.00022 20.7 0.1 0.00053 19.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KII94317.1 - 0.00031 20.9 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KII94317.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 KII94317.1 - 0.028 13.8 0.2 8.3 5.7 0.1 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KII94317.1 - 0.032 13.8 0.3 0.27 10.7 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KII94317.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KII94317.1 - 0.16 12.3 1.0 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain Glyco_hydro_53 PF07745.13 KII94317.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Ribonuc_L-PSP PF01042.21 KII94318.1 - 1.1e-40 138.4 0.2 1.3e-40 138.2 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proteasome PF00227.26 KII94319.1 - 6.3e-58 195.4 0.1 7.9e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII94319.1 - 6.6e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Inositol_P PF00459.25 KII94320.1 - 4.4e-66 223.2 0.0 5.3e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Aldo_ket_red PF00248.21 KII94321.1 - 9.1e-46 156.4 0.0 1.2e-44 152.7 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Dor1 PF04124.12 KII94322.1 - 1.2e-51 175.5 0.0 2.4e-50 171.2 0.0 2.1 1 1 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 KII94322.1 - 0.002 18.2 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 B56 PF01603.20 KII94322.1 - 0.21 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) Toxin_7 PF05980.12 KII94323.1 - 0.25 11.6 6.2 0.55 10.5 0.5 2.8 2 0 0 2 2 2 0 Toxin 7 F-box-like PF12937.7 KII94324.1 - 5.1e-07 29.5 0.4 1.2e-06 28.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like DUF531 PF04407.12 KII94324.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) TPR_1 PF00515.28 KII94325.1 - 1.9e-06 27.5 0.5 0.23 11.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII94325.1 - 9.1e-06 25.4 4.2 0.019 15.1 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KII94325.1 - 2.3e-05 24.4 0.0 0.0017 18.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 KII94325.1 - 0.053 14.0 2.2 0.053 14.0 2.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TPR_7 PF13176.6 KII94325.1 - 0.057 13.5 0.0 21 5.4 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.24 KII94325.1 - 0.32 11.0 8.9 3.7 7.6 0.5 3.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KII94325.1 - 1.6 8.6 8.7 3.9 7.4 3.1 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KII94325.1 - 5.2 7.3 16.5 0.31 11.2 5.5 2.8 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 KII94325.1 - 5.5 7.7 7.6 9.4 7.0 1.9 2.7 1 1 1 2 2 2 0 Torus domain Dus PF01207.17 KII94326.1 - 1e-48 166.0 0.0 2.2e-48 165.0 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Radical_SAM PF04055.21 KII94326.1 - 0.1 13.0 0.1 0.43 10.9 0.1 1.9 2 1 0 2 2 2 0 Radical SAM superfamily Asp PF00026.23 KII94327.1 - 1.1e-77 261.5 11.1 1.4e-77 261.2 11.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII94327.1 - 1.6e-09 38.2 4.4 9.4e-05 22.7 0.2 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII94327.1 - 2.6e-06 27.3 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF1918 PF08940.11 KII94327.1 - 0.03 13.9 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) GvpG PF05120.12 KII94328.1 - 0.18 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein G TTL PF03133.15 KII94329.1 - 1.8e-40 138.9 0.0 2.7e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 KII94330.1 - 1e-34 120.1 0.0 3.5e-24 85.5 0.0 3.0 1 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Abhydrolase_6 PF12697.7 KII94331.1 - 0.0012 19.5 0.5 0.0015 19.2 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII94331.1 - 0.019 14.2 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CUT PF02376.15 KII94331.1 - 0.19 11.9 0.1 7.8 6.7 0.0 2.9 2 1 0 2 2 2 0 CUT domain GldM_N PF12081.8 KII94332.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain Mpp10 PF04006.12 KII94333.1 - 2.3e-112 376.5 57.7 3e-110 369.5 57.7 2.3 1 1 0 1 1 1 1 Mpp10 protein CAP_N PF01213.19 KII94333.1 - 0.13 11.8 6.6 0.38 10.2 0.8 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal V-SNARE_C PF12352.8 KII94334.1 - 0.0021 18.3 3.2 0.39 11.0 0.5 2.9 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Transformer PF06495.11 KII94334.1 - 0.53 10.3 8.2 1.6 8.8 8.3 1.7 1 1 0 1 1 1 0 Fruit fly transformer protein FlaC_arch PF05377.11 KII94335.1 - 0.095 13.1 0.4 0.18 12.2 0.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HMMR_N PF15905.5 KII94335.1 - 0.18 11.3 0.4 0.25 10.8 0.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SAD_SRA PF02182.17 KII94336.1 - 3.6e-45 153.5 0.1 5.4e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain SSP160 PF06933.11 KII94339.1 - 0.0049 15.2 17.7 0.0049 15.1 17.7 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 CEL_III_C PF18054.1 KII94339.1 - 0.56 10.3 3.8 0.73 9.9 3.8 1.1 1 0 0 1 1 1 0 CEL-III C-terminal UPF0160 PF03690.13 KII94340.1 - 3.5e-138 460.6 0.0 4e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MARVEL PF01284.23 KII94341.1 - 0.015 15.4 10.2 0.022 14.8 10.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2085 PF09858.9 KII94341.1 - 5.6 7.5 8.5 2.8 8.5 5.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) Glyco_transf_41 PF13844.6 KII94343.1 - 2.5e-71 240.5 6.2 1.4e-44 152.3 0.1 4.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 KII94343.1 - 2e-11 43.2 0.0 0.0029 17.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KII94343.1 - 2.4e-10 39.9 0.3 0.0002 21.0 0.1 3.9 3 1 1 4 4 4 3 TPR repeat TPR_17 PF13431.6 KII94343.1 - 1.3e-08 34.7 0.1 0.00038 20.6 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII94343.1 - 7e-07 28.9 0.0 0.014 15.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KII94343.1 - 3.2e-06 26.9 0.0 0.05 13.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KII94343.1 - 0.00045 20.7 0.0 0.039 14.4 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KII94343.1 - 0.00064 20.3 0.0 0.17 12.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII94343.1 - 0.00069 19.5 0.1 0.29 11.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII94343.1 - 0.00081 19.6 0.0 0.091 13.1 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII94343.1 - 0.0017 19.0 0.0 2.8 9.0 0.0 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII94343.1 - 0.0078 16.1 0.2 0.5 10.3 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII94343.1 - 0.078 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4444 PF14563.6 KII94344.1 - 0.18 11.5 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Aldose_epim PF01263.20 KII94347.1 - 8.2e-32 110.7 0.0 9.2e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase cEGF PF12662.7 KII94348.1 - 0.0068 16.3 1.1 0.0068 16.3 1.1 4.0 5 1 0 5 5 5 1 Complement Clr-like EGF-like zf-C2H2_4 PF13894.6 KII94350.1 - 4.6e-05 23.9 32.8 2.6 9.1 0.3 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.7 KII94350.1 - 5.4e-05 23.4 28.6 0.14 12.5 0.5 6.5 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KII94350.1 - 0.00074 19.8 6.5 0.00074 19.8 6.5 3.4 1 1 3 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KII94350.1 - 0.0014 19.0 33.6 0.36 11.4 0.4 7.0 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KII94350.1 - 0.07 13.4 0.4 0.07 13.4 0.4 5.4 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.27 KII94351.1 - 7.7e-47 159.3 0.0 1.2e-22 80.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KII94351.1 - 1.1e-40 139.3 45.9 2.2e-24 86.0 15.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter RsgA_GTPase PF03193.16 KII94351.1 - 9.6e-09 35.4 2.0 4e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KII94351.1 - 1.7e-08 34.7 4.1 0.24 11.2 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII94351.1 - 7e-07 28.9 1.0 0.022 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KII94351.1 - 2.3e-05 23.9 0.1 0.06 12.8 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KII94351.1 - 0.00011 22.2 0.1 0.51 10.2 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KII94351.1 - 0.00012 22.4 1.4 0.099 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII94351.1 - 0.00012 22.5 2.0 0.021 15.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KII94351.1 - 0.00014 21.5 0.2 0.21 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KII94351.1 - 0.00038 21.0 0.6 0.14 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KII94351.1 - 0.00041 20.6 1.3 0.88 9.8 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KII94351.1 - 0.00078 19.2 0.4 0.62 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KII94351.1 - 0.0014 18.8 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.18 KII94351.1 - 0.0019 18.0 1.9 0.39 10.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 KII94351.1 - 0.0037 17.8 0.3 0.67 10.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KII94351.1 - 0.013 15.8 0.1 0.35 11.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KII94351.1 - 0.027 14.4 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KII94351.1 - 0.031 14.0 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KII94351.1 - 0.054 13.2 0.3 10 5.8 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KII94351.1 - 0.091 13.2 0.6 2.6 8.5 0.1 2.4 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 KII94351.1 - 0.092 12.8 3.5 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CbtB PF09489.10 KII94351.1 - 0.1 12.7 2.6 12 6.1 0.2 3.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) AAA_17 PF13207.6 KII94351.1 - 0.13 12.6 0.3 5.6 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KII94351.1 - 0.18 11.8 0.3 13 5.8 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KII94351.1 - 0.21 11.6 1.0 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KII94351.1 - 0.36 10.7 2.6 2.3 8.1 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KII94351.1 - 0.48 10.0 3.5 10 5.7 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KII94351.1 - 2 8.1 3.8 28 4.4 1.2 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 KII94351.1 - 3 7.9 4.4 18 5.3 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain F-box-like PF12937.7 KII94353.1 - 0.00047 20.0 4.8 0.0018 18.1 4.8 2.1 1 0 0 1 1 1 1 F-box-like HEAT PF02985.22 KII94354.1 - 3.5e-41 135.7 13.4 0.0043 17.2 0.1 13.6 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KII94354.1 - 1.2e-32 112.1 12.1 1.7e-10 41.1 0.0 7.5 3 3 3 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 KII94354.1 - 6.4e-13 49.1 0.2 0.0076 16.8 0.0 7.5 4 2 5 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KII94354.1 - 8.5e-11 42.1 9.3 0.039 14.5 0.0 9.0 8 2 2 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 KII94354.1 - 7e-10 39.2 1.0 0.041 13.9 0.0 5.0 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KII94354.1 - 5.1e-08 31.9 2.7 0.00029 19.6 0.7 3.7 2 2 1 3 3 3 3 Adaptin N terminal region Arm PF00514.23 KII94354.1 - 3.8e-05 23.6 6.8 1.3 9.1 0.0 6.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 KII94354.1 - 7.4e-05 23.0 0.0 0.27 11.6 0.0 4.5 4 0 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain Ecm29 PF13001.7 KII94354.1 - 0.016 13.9 0.4 34 2.9 0.2 4.3 3 1 1 5 5 5 0 Proteasome stabiliser Peripla_BP_2 PF01497.18 KII94354.1 - 0.048 13.2 0.1 1.3 8.5 0.0 2.4 2 1 1 3 3 3 0 Periplasmic binding protein HEAT_PBS PF03130.16 KII94354.1 - 0.083 13.6 5.6 3.8 8.4 0.2 6.0 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat Arch_flagellin PF01917.16 KII94355.1 - 0.15 12.2 1.5 0.24 11.6 1.5 1.3 1 0 0 1 1 1 0 Archaebacterial flagellin I_LWEQ PF01608.17 KII94355.1 - 0.49 10.6 2.9 22 5.3 0.0 2.3 2 0 0 2 2 2 0 I/LWEQ domain PAP1 PF08601.10 KII94355.1 - 1.2 8.8 8.6 1.7 8.3 8.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4870 PF09685.10 KII94356.1 - 0.059 13.5 1.1 0.085 13.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) HTH_43 PF09904.9 KII94356.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_S24e PF01282.19 KII94357.1 - 2.7e-34 116.9 0.1 4.3e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Actin PF00022.19 KII94358.1 - 6.9e-129 430.0 0.0 3.1e-128 427.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KII94358.1 - 0.031 13.1 0.0 0.32 9.7 0.0 2.1 2 1 0 2 2 2 0 MreB/Mbl protein SVIP PF15811.5 KII94360.1 - 0.0019 18.6 3.2 0.0025 18.2 3.2 1.3 1 0 0 1 1 1 1 Small VCP/p97-interacting protein GPI2 PF06432.11 KII94361.1 - 7.2e-87 291.4 9.2 8.1e-87 291.2 9.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase bZIP_1 PF00170.21 KII94363.1 - 2.9e-05 24.1 3.6 6.5e-05 22.9 3.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII94363.1 - 0.05 13.7 1.0 0.05 13.7 1.0 2.9 2 1 1 3 3 3 0 Basic region leucine zipper SlyX PF04102.12 KII94363.1 - 0.09 13.4 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 SlyX YabA PF06156.13 KII94363.1 - 0.13 12.9 0.1 0.25 12.0 0.1 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 KII94363.1 - 0.18 12.0 0.4 0.35 11.1 0.4 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 KII94363.1 - 0.25 11.8 1.1 0.49 10.9 1.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB ANAPC4 PF12896.7 KII94364.1 - 2.3e-39 135.0 0.0 4.1e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KII94364.1 - 4.2e-07 30.2 0.1 9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KII94365.1 - 2.3e-47 161.0 0.1 1.4e-46 158.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94365.1 - 2.1e-30 105.3 0.0 3e-28 98.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Pkinase_fungal PF17667.1 KII94366.1 - 1.2e-41 142.9 0.0 2.5e-21 76.0 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KII94366.1 - 0.00029 20.8 0.1 0.0014 18.6 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII94366.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII94366.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.20 KII94366.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Tail_tube PF10618.9 KII94366.1 - 0.14 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein Haspin_kinase PF12330.8 KII94366.1 - 0.2 10.6 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_16 PF00722.21 KII94367.1 - 1.7e-09 37.4 0.0 3.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SurE PF01975.17 KII94368.1 - 1.3e-44 152.3 0.0 1.5e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE RasGEF PF00617.19 KII94369.1 - 4.9e-31 108.3 0.0 8.5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KII94369.1 - 2.3e-08 34.2 0.0 8.8e-08 32.3 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KII94369.1 - 3.8e-05 23.3 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 Ras family Arf PF00025.21 KII94369.1 - 0.0022 17.5 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KII94369.1 - 0.005 17.2 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KII94369.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KII94369.1 - 0.091 13.0 0.2 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KII94369.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII94369.1 - 0.17 11.8 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Ribosomal_L15e PF00827.17 KII94371.1 - 5.1e-89 297.1 10.6 5.9e-89 296.9 10.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 MFS_1 PF07690.16 KII94372.1 - 7.8e-21 74.4 21.7 1.1e-19 70.6 19.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.20 KII94372.1 - 0.0015 17.6 0.9 0.0015 17.6 0.9 3.2 3 1 0 3 3 3 1 Phosphate transporter family Lipase_3 PF01764.25 KII94373.1 - 8.5e-23 80.8 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KII94373.1 - 5.2e-05 23.9 4.2 5.2e-05 23.9 4.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII94373.1 - 0.039 13.4 0.0 7.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KII94373.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HSCB_C PF07743.13 KII94374.1 - 7.9e-17 61.5 2.5 1.3e-16 60.8 0.9 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KII94374.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 KII94374.1 - 0.052 13.6 1.2 0.1 12.7 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KII94374.1 - 0.84 9.1 7.5 1.8 8.1 7.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 KII94374.1 - 0.94 9.6 7.3 2.1 8.5 7.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 MFS_1 PF07690.16 KII94376.1 - 5.4e-38 130.8 24.5 5.4e-38 130.8 24.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII94376.1 - 1.7e-14 53.5 5.6 6e-14 51.7 5.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter WD40 PF00400.32 KII94377.1 - 5 8.2 14.6 6.8 7.7 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Adaptin_N PF01602.20 KII94378.1 - 2.1e-124 416.0 6.7 2.9e-124 415.5 6.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KII94378.1 - 1e-39 135.2 0.0 1.9e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KII94378.1 - 6.4e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KII94378.1 - 0.041 14.1 0.4 0.13 12.5 0.4 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 KII94378.1 - 0.053 12.6 0.2 0.77 8.8 0.1 2.6 3 0 0 3 3 3 0 Dopey, N-terminal HEAT PF02985.22 KII94378.1 - 0.093 13.0 0.5 1.6 9.2 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat HA2 PF04408.23 KII94379.1 - 4.9e-18 65.4 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KII94379.1 - 1.6e-13 50.9 0.0 3.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 KII94379.1 - 2e-07 31.6 0.0 0.00055 20.6 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 KII94379.1 - 2e-06 27.7 0.0 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KII94379.1 - 0.0011 19.3 0.1 0.0037 17.6 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KII94379.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Pex24p PF06398.11 KII94380.1 - 2.5e-09 36.6 0.3 3.4e-09 36.2 0.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin F-box-like PF12937.7 KII94381.1 - 0.00055 19.8 2.5 0.00061 19.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like NUDIX PF00293.28 KII94382.1 - 5.6e-25 87.9 0.0 7.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.13 KII94383.1 - 6.4e-25 87.5 0.0 1.1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KII94383.1 - 1.2e-11 43.7 0.0 2.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3292 PF11696.8 KII94384.1 - 1.4e-13 50.1 2.3 2.1e-07 29.8 0.8 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3292) Reticulon PF02453.17 KII94384.1 - 0.0041 17.1 3.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 2 Reticulon PRT_C PF08372.10 KII94384.1 - 0.045 13.5 0.1 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF3306 PF11748.8 KII94384.1 - 3 8.7 6.5 12 6.8 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) STAC2_u1 PF16664.5 KII94384.1 - 7.5 7.0 7.8 16 5.9 4.8 2.5 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 INCENP_ARK-bind PF03941.15 KII94385.1 - 1.7e-19 69.5 2.7 1.7e-19 69.5 2.7 3.6 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DCP2 PF05026.13 KII94386.1 - 2.2e-32 111.2 2.5 3.6e-32 110.5 2.5 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KII94386.1 - 9.1e-16 58.1 0.2 1.9e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Plavaka PF18759.1 KII94388.1 - 9.7e-41 140.0 0.0 1.6e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase SBP PF03110.14 KII94388.1 - 0.12 12.7 6.3 0.35 11.2 6.3 1.8 1 0 0 1 1 1 0 SBP domain F-box-like PF12937.7 KII94389.1 - 6.4e-07 29.2 0.4 1.3e-06 28.2 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94389.1 - 7.3e-06 25.7 0.2 1.4e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain zf-CHCC PF10276.9 KII94390.1 - 2.6e-17 62.5 2.8 4.2e-17 61.9 2.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain Sporozoite_P67 PF05642.11 KII94390.1 - 4.7 5.2 5.1 5.6 4.9 5.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 KII94391.1 - 1.1e-52 179.0 0.0 1.4e-51 175.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94391.1 - 2e-23 83.0 0.0 5.7e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase NAP PF00956.18 KII94391.1 - 0.065 12.4 3.3 0.097 11.8 3.3 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Pannexin_like PF12534.8 KII94391.1 - 1.1 8.2 3.7 1.8 7.5 3.7 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Pribosyltran_N PF13793.6 KII94392.1 - 1.7e-44 150.5 0.7 3.3e-43 146.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KII94392.1 - 2e-36 125.8 1.8 9.2e-31 107.3 0.9 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KII94392.1 - 6.4e-15 55.0 1.5 1.4e-14 53.9 0.8 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KII94392.1 - 0.0026 17.3 0.2 0.0044 16.5 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF848 PF05852.11 KII94392.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Chlorosome_CsmC PF11098.8 KII94392.1 - 0.27 11.2 1.9 0.36 10.8 0.5 1.8 2 0 0 2 2 2 0 Chlorosome envelope protein C UbiA PF01040.18 KII94393.1 - 1.8e-55 188.0 24.2 5.9e-55 186.3 24.2 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.7 KII94394.1 - 1.5e-08 34.4 0.4 2.8e-08 33.5 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94394.1 - 5.6e-07 29.3 0.3 1.1e-06 28.4 0.3 1.4 1 0 0 1 1 1 1 F-box domain AAA_2 PF07724.14 KII94395.1 - 3.1e-49 167.4 0.0 1.2e-45 155.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KII94395.1 - 6.7e-33 112.7 6.2 2.5e-32 110.9 1.7 3.4 3 0 0 3 3 3 1 AAA lid domain ClpB_D2-small PF10431.9 KII94395.1 - 2.4e-25 88.4 0.1 9.1e-25 86.5 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KII94395.1 - 5.2e-24 85.2 0.0 2e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 KII94395.1 - 3.5e-16 59.0 8.5 1e-12 48.0 0.7 4.3 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KII94395.1 - 8.6e-14 51.7 0.1 7.2e-07 29.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KII94395.1 - 7.4e-12 46.0 1.4 3.8e-06 27.4 0.0 4.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KII94395.1 - 5.2e-09 36.5 0.0 0.02 15.1 0.0 4.4 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 KII94395.1 - 8.3e-08 32.1 0.0 0.00016 21.4 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 KII94395.1 - 1.4e-06 28.2 0.0 0.0016 18.2 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 KII94395.1 - 7.7e-06 25.8 0.0 0.039 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KII94395.1 - 7.7e-06 25.4 0.1 0.015 14.7 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KII94395.1 - 8e-05 23.2 0.0 0.17 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KII94395.1 - 0.00011 22.4 0.0 0.23 11.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KII94395.1 - 0.00011 21.7 0.0 0.11 11.9 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 KII94395.1 - 0.00012 21.5 0.8 1.2 8.3 0.0 3.3 2 1 1 3 3 3 2 TIP49 P-loop domain NACHT PF05729.12 KII94395.1 - 0.00028 20.8 0.0 0.085 12.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KII94395.1 - 0.00031 21.1 0.2 1.8 9.0 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 KII94395.1 - 0.00089 18.8 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 KII94395.1 - 0.0014 18.4 0.7 4.3 7.1 0.4 3.7 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 KII94395.1 - 0.0037 17.5 0.0 0.56 10.4 0.0 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KII94395.1 - 0.0049 16.2 0.0 0.5 9.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ERM PF00769.19 KII94395.1 - 0.0086 15.9 11.8 0.019 14.8 11.8 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TsaE PF02367.17 KII94395.1 - 0.0088 16.0 0.0 6.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KII94395.1 - 0.0099 16.1 1.8 2.1 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KII94395.1 - 0.013 16.1 1.1 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter PhoH PF02562.16 KII94395.1 - 0.018 14.5 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 KII94395.1 - 0.046 13.4 0.0 14 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KII94395.1 - 0.053 13.4 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase DUF3450 PF11932.8 KII94395.1 - 0.057 12.7 4.2 0.12 11.7 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FACT-Spt16_Nlob PF14826.6 KII94395.1 - 0.068 13.0 0.0 0.23 11.3 0.1 1.8 2 0 0 2 2 1 0 FACT complex subunit SPT16 N-terminal lobe domain CbiA PF01656.23 KII94395.1 - 0.069 13.2 0.1 11 6.1 0.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Torsin PF06309.11 KII94395.1 - 0.078 13.1 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_19 PF13245.6 KII94395.1 - 0.085 13.2 0.3 9.3 6.6 0.1 3.2 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 KII94395.1 - 0.11 12.5 0.0 5.4 7.0 0.0 3.0 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 KII94395.1 - 0.13 12.0 0.8 12 5.4 0.4 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KII94395.1 - 0.16 11.7 0.1 12 5.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KII94395.1 - 0.26 11.2 7.8 5.8 6.8 0.1 4.3 3 2 1 5 5 5 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KII94395.1 - 0.37 10.3 1.9 12 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain Atg14 PF10186.9 KII94395.1 - 0.37 9.8 5.6 0.66 9.0 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cytidylate_kin PF02224.18 KII94395.1 - 0.4 10.4 5.7 19 4.9 0.8 3.8 4 0 0 4 4 4 0 Cytidylate kinase Spc7 PF08317.11 KII94395.1 - 2 7.2 10.7 3.6 6.4 10.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PV-1 PF06637.11 KII94395.1 - 3 6.6 9.3 4.9 5.9 9.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) AAA_23 PF13476.6 KII94395.1 - 8.4 6.8 18.0 32 5.0 0.0 3.8 3 1 0 3 3 2 0 AAA domain Pkinase PF00069.25 KII94396.1 - 5.6e-76 255.4 0.0 6.9e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94396.1 - 3.9e-36 124.7 0.0 6.2e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII94396.1 - 0.00023 20.2 0.0 0.00097 18.2 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KII94396.1 - 0.026 13.9 0.5 0.075 12.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KII94396.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KII94397.1 - 5.5e-76 255.4 0.0 7e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94397.1 - 2.5e-36 125.3 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KII94397.1 - 0.00048 19.2 0.0 0.0025 16.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KII94397.1 - 0.0047 16.6 0.1 0.061 12.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 KII94397.1 - 0.0092 15.3 0.0 0.031 13.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KII94397.1 - 0.14 12.1 0.0 0.14 12.1 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.10 KII94397.1 - 4.4 5.9 22.0 5.9 5.4 22.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4810 PF16068.5 KII94397.1 - 4.6 7.8 8.8 2.3 8.8 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) CCDC53 PF10152.9 KII94397.1 - 7.4 7.0 6.8 14 6.1 6.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Utp12 PF04003.12 KII94398.1 - 1.5e-25 89.6 0.0 2.6e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KII94398.1 - 5.3e-07 30.2 1.1 0.14 13.1 0.4 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat SWIRM-assoc_2 PF16496.5 KII94398.1 - 4.2 6.1 8.2 9.5 5.0 8.2 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Fapy_DNA_glyco PF01149.24 KII94399.1 - 5e-29 101.3 0.1 9.9e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KII94399.1 - 1.9e-20 72.6 0.0 3.1e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KII94399.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 KII94399.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 MFS_1 PF07690.16 KII94400.1 - 9.7e-52 176.0 29.9 1.6e-34 119.4 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KII94400.1 - 1.3e-08 34.2 17.6 0.0007 18.6 2.7 4.0 2 2 2 4 4 4 3 MFS_1 like family MFS_2 PF13347.6 KII94400.1 - 2.6e-07 29.5 23.6 3.9e-06 25.7 2.1 3.6 2 2 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 KII94400.1 - 6.3e-05 21.5 1.4 6.3e-05 21.5 1.4 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KII94400.1 - 0.051 12.9 15.1 0.12 11.7 5.0 2.5 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KII94400.1 - 0.052 11.9 10.9 0.018 13.4 2.6 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector OAD_gamma PF04277.13 KII94400.1 - 0.12 13.0 0.4 0.77 10.4 0.4 2.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UNC-93 PF05978.16 KII94400.1 - 1.7 8.4 7.7 0.13 12.0 1.6 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 HATPase_c PF02518.26 KII94402.1 - 1.9e-27 96.0 0.1 5.4e-27 94.5 0.0 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KII94402.1 - 3.9e-20 72.1 0.0 7.1e-19 68.0 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 KII94402.1 - 4.6e-15 56.4 0.4 5.3e-14 53.0 0.3 2.8 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 KII94402.1 - 4.9e-14 52.1 0.0 2.4e-13 49.9 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KII94402.1 - 4.5e-12 46.4 0.0 1.5e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KII94402.1 - 8.9e-09 36.1 0.0 2.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KII94402.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94402.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 KII94402.1 - 7.6e-06 26.3 0.0 2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.6 KII94402.1 - 0.001 19.3 3.4 0.023 15.0 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HATPase_c_3 PF13589.6 KII94402.1 - 0.0048 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF815 PF05673.13 KII94402.1 - 0.032 13.4 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KII94402.1 - 0.071 13.0 3.8 0.61 10.0 1.4 3.6 3 1 0 3 3 3 0 NACHT domain AAA_5 PF07728.14 KII94402.1 - 0.078 13.0 0.2 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4140 PF13600.6 KII94402.1 - 0.27 11.7 1.3 6 7.4 0.0 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DEAD PF00270.29 KII94403.1 - 3.6e-37 127.8 0.1 5.6e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94403.1 - 1.3e-26 93.1 0.0 7.5e-25 87.4 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII94403.1 - 3e-08 33.9 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 KII94404.1 - 8.5e-56 185.9 0.2 1.2e-18 66.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII94404.1 - 0.026 13.7 0.1 2.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease ATP-synt_ab_N PF02874.23 KII94404.1 - 0.034 14.7 0.0 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain Glyco_hydro_43 PF04616.14 KII94405.1 - 1.4e-17 64.0 5.6 2.3e-17 63.3 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WD40 PF00400.32 KII94406.1 - 3e-09 37.4 1.1 0.19 12.7 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat RNB PF00773.19 KII94407.1 - 2e-96 323.2 0.0 3e-96 322.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 KII94407.1 - 1.9e-25 89.3 0.0 5.1e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 KII94407.1 - 3e-24 84.8 2.2 6.4e-24 83.7 2.2 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 KII94407.1 - 5.7e-15 55.1 0.0 2.2e-14 53.2 0.0 2.1 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KII94407.1 - 4.5e-09 36.7 0.0 1.4e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 KII94407.1 - 3.2e-08 33.6 3.6 0.00033 20.7 0.0 4.8 5 0 0 5 5 5 2 Cold shock domain OB_RNB PF08206.11 KII94407.1 - 0.072 12.8 1.4 0.49 10.1 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain His_Phos_2 PF00328.22 KII94408.1 - 8.1e-13 48.5 0.0 2.5e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 KII94409.1 - 6.7e-56 189.6 0.0 9.2e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94409.1 - 3.2e-23 82.4 0.0 4.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII94409.1 - 0.00057 19.3 1.4 0.0012 18.3 0.2 2.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KII94409.1 - 0.068 12.5 0.2 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L19e PF01280.20 KII94410.1 - 2.7e-61 205.8 9.4 2.7e-61 205.8 9.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e Formyl_trans_N PF00551.19 KII94411.1 - 1.4e-41 142.2 0.0 1.7e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MOZ_SAS PF01853.18 KII94412.1 - 1.8e-65 220.0 0.0 2.3e-62 209.8 0.0 2.4 3 0 0 3 3 3 2 MOZ/SAS family zf-MYST PF17772.1 KII94412.1 - 2.4e-17 62.3 2.1 3.3e-09 36.2 0.1 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 KII94412.1 - 3.1e-07 30.2 0.3 5.9e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KII94412.1 - 0.05 14.0 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Agenet PF05641.12 KII94412.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 Agenet domain SKG6 PF08693.10 KII94413.1 - 0.0064 15.9 0.4 0.011 15.1 0.4 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SCF PF02404.15 KII94413.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Stem cell factor Pkinase PF00069.25 KII94414.1 - 2.1e-56 191.2 0.0 2.7e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94414.1 - 2.5e-26 92.5 0.0 3.4e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII94414.1 - 2.7e-07 30.8 0.2 5.7e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KII94414.1 - 3e-05 23.5 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KII94414.1 - 4.2e-05 23.0 0.0 6.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KII94414.1 - 4.2e-05 22.5 0.0 6.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 KII94414.1 - 0.00016 22.3 0.2 0.00074 20.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain FTA2 PF13095.6 KII94414.1 - 0.00033 20.3 0.0 0.7 9.5 0.0 2.6 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KII94414.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KII94414.1 - 0.02 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain bZIP_Maf PF03131.17 KII94414.1 - 0.13 12.8 0.1 2.2 8.8 0.1 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Metallophos PF00149.28 KII94415.1 - 4.2e-09 37.2 0.2 6.1e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CS PF04969.16 KII94415.1 - 4.5e-09 37.2 0.0 3.2e-08 34.5 0.0 2.4 3 0 0 3 3 3 1 CS domain Metallophos_2 PF12850.7 KII94415.1 - 0.0054 16.9 0.1 3.5 7.8 0.0 2.4 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain C2 PF00168.30 KII94416.1 - 1.4e-20 73.4 0.0 4.6e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain IMUP PF15761.5 KII94416.1 - 0.0043 17.7 2.3 0.0043 17.7 2.3 1.8 2 0 0 2 2 2 1 Immortalisation up-regulated protein Cul7 PF11515.8 KII94416.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 SMP_LBD PF17047.5 KII94416.1 - 0.092 12.2 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain DUF2076 PF09849.9 KII94416.1 - 0.14 12.2 5.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) GAIN PF16489.5 KII94416.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain Vps35 PF03635.17 KII94417.1 - 0 1024.9 0.0 0 1024.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 KII94417.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Endoribonuclease L-PSP VHS PF00790.19 KII94418.1 - 1.2e-41 141.8 1.9 6.2e-41 139.5 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KII94418.1 - 1.4e-16 60.4 6.3 2.3e-16 59.7 6.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KII94418.1 - 4.7e-06 26.2 13.0 0.012 15.5 0.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KII94418.1 - 0.046 13.9 3.6 0.1 12.8 3.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Hrs_helical PF12210.8 KII94418.1 - 0.1 13.2 0.4 0.25 11.9 0.1 1.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.14 KII94418.1 - 0.12 12.8 0.5 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 GAT domain Joubert PF15392.6 KII94418.1 - 0.47 10.1 4.9 0.94 9.1 4.9 1.5 1 0 0 1 1 1 0 Joubert syndrome-associated DZR PF12773.7 KII94418.1 - 0.76 9.9 7.0 2.9 8.0 3.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KII94418.1 - 0.97 9.4 3.2 0.77 9.7 0.9 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RNA_pol_Rpb1_1 PF04997.12 KII94419.1 - 1.4e-107 359.6 0.0 2e-107 359.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KII94419.1 - 1.3e-104 349.3 0.0 1.9e-104 348.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KII94419.1 - 1.9e-73 246.1 0.0 3.3e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KII94419.1 - 4e-69 232.3 0.0 8.2e-69 231.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KII94419.1 - 1.5e-49 168.0 0.0 4.1e-49 166.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KII94419.1 - 8.3e-46 155.3 0.0 1.5e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KII94419.1 - 5.7e-35 119.5 0.0 1.2e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KII94419.1 - 0.00032 20.9 206.4 0.023 15.0 10.3 14.0 6 2 8 16 16 16 12 RNA polymerase Rpb1 C-terminal repeat ABC_membrane PF00664.23 KII94420.1 - 9.4e-44 150.1 26.6 1.2e-22 80.9 3.9 4.3 3 1 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KII94420.1 - 2.9e-38 131.5 0.0 2.9e-24 86.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 KII94420.1 - 1.8e-06 28.4 0.3 0.12 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KII94420.1 - 1.6e-05 24.9 0.8 0.036 13.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KII94420.1 - 2.9e-05 23.7 0.1 0.26 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KII94420.1 - 6.2e-05 23.6 0.5 0.0042 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KII94420.1 - 0.00041 20.0 1.7 0.68 9.7 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KII94420.1 - 0.00071 19.1 3.3 1 8.7 0.0 4.1 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 KII94420.1 - 0.0011 18.5 0.3 1.4 8.4 0.0 2.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_5 PF07728.14 KII94420.1 - 0.0061 16.6 1.2 1.5 8.8 0.1 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII94420.1 - 0.0066 16.7 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KII94420.1 - 0.01 15.8 0.5 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KII94420.1 - 0.012 15.7 0.3 0.74 9.9 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KII94420.1 - 0.03 14.7 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KII94420.1 - 0.04 13.0 0.1 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KII94420.1 - 0.043 13.9 1.0 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KII94420.1 - 0.057 13.1 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KII94420.1 - 0.074 12.8 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Adeno_IVa2 PF02456.15 KII94420.1 - 0.084 11.6 0.4 0.63 8.8 0.0 2.3 3 0 0 3 3 3 0 Adenovirus IVa2 protein Roc PF08477.13 KII94420.1 - 0.17 12.1 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 KII94420.1 - 0.17 12.2 1.5 22 5.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.23 KII94420.1 - 0.22 11.6 1.2 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KII94420.1 - 0.25 11.1 0.7 7 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 KII94421.1 - 5.1e-20 71.8 0.6 8.1e-20 71.1 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII94421.1 - 6.8e-07 29.2 0.0 0.00014 21.7 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KII94421.1 - 0.00012 23.1 0.1 0.00032 21.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GPI-anchored PF10342.9 KII94422.1 - 0.00097 19.8 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Collagen PF01391.18 KII94422.1 - 0.51 10.1 8.4 0.93 9.3 8.4 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Med9 PF07544.13 KII94423.1 - 3e-07 30.4 0.3 3.7e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Cupin_4 PF08007.12 KII94423.1 - 0.059 12.8 0.2 0.066 12.7 0.2 1.0 1 0 0 1 1 1 0 Cupin superfamily protein Prefoldin_3 PF13758.6 KII94423.1 - 0.082 13.0 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit Fer4_14 PF13394.6 KII94423.1 - 0.087 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain DEAD PF00270.29 KII94424.1 - 6.4e-37 127.0 0.1 9.7e-37 126.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94424.1 - 5.8e-23 81.4 0.0 1.9e-22 79.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII94424.1 - 6.7e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 KII94425.1 - 1.8e-17 63.5 1.0 2.3e-17 63.2 1.0 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII94425.1 - 7.4e-09 36.1 0.4 8.6e-09 35.9 0.4 1.0 1 0 0 1 1 1 1 HMG-box domain PolyA_pol PF01743.20 KII94426.1 - 2.9e-23 82.7 0.1 5.6e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KII94426.1 - 0.00016 21.4 0.3 0.00069 19.3 0.0 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF4287 PF14117.6 KII94426.1 - 0.0027 17.8 0.5 24 5.1 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4287) TetR_C_7 PF14246.6 KII94426.1 - 0.083 12.9 0.3 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain DNA_meth_N PF18284.1 KII94426.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 DNA methylase N-terminal domain FcoT PF10862.8 KII94427.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 FcoT-like thioesterase domain Glyco_hydro_16 PF00722.21 KII94428.1 - 6.8e-05 22.4 0.1 0.00023 20.7 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Arm PF00514.23 KII94429.1 - 2.3e-71 233.9 28.1 4.9e-13 48.6 0.1 11.7 11 1 1 12 12 12 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KII94429.1 - 2e-20 72.9 10.5 0.00092 19.7 0.3 8.1 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 KII94429.1 - 2.7e-18 66.1 5.5 0.02 15.3 0.0 7.2 4 3 1 6 6 6 5 HEAT repeats HEAT PF02985.22 KII94429.1 - 3.1e-16 58.1 11.6 0.19 12.1 0.0 9.8 9 0 0 9 9 9 5 HEAT repeat Adaptin_N PF01602.20 KII94429.1 - 1.8e-11 43.3 9.6 2.5e-08 32.9 0.2 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 KII94429.1 - 2.2e-11 43.7 9.3 1.1e-07 31.6 1.4 2.4 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KII94429.1 - 2.1e-10 39.4 2.4 3.1e-10 38.9 2.4 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KII94429.1 - 5.2e-09 35.8 7.9 0.0011 18.3 1.1 4.3 2 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 KII94429.1 - 1.6e-06 28.3 5.6 0.012 15.6 0.1 5.1 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KII94429.1 - 0.00047 20.1 6.6 1.3 8.9 0.0 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KII94429.1 - 0.0042 17.2 3.5 31 4.7 0.1 4.8 1 1 5 6 6 6 0 V-ATPase subunit H HEAT_PBS PF03130.16 KII94429.1 - 0.0096 16.5 9.0 56 4.8 0.2 7.1 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KII94429.1 - 0.037 14.6 0.0 8.9 7.0 0.0 3.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KII94429.1 - 0.18 11.9 4.1 0.43 10.6 0.2 3.4 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RasGEF_N_2 PF14663.6 KII94429.1 - 2.3 8.6 4.8 29 5.1 0.2 4.0 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FcoT PF10862.8 KII94430.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain ADH_zinc_N PF00107.26 KII94432.1 - 2.2e-28 98.8 0.6 3.5e-28 98.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII94432.1 - 1.1e-20 75.0 0.0 2.9e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KII94432.1 - 5e-09 36.0 0.0 1.7e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KII94432.1 - 0.03 13.6 0.2 0.064 12.5 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane PF00664.23 KII94433.1 - 3.8e-54 184.2 27.8 6.5e-29 101.4 7.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KII94433.1 - 1.4e-43 148.7 0.1 9.4e-26 91.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KII94433.1 - 2.8e-09 36.7 4.5 0.073 12.5 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KII94433.1 - 1.6e-06 28.6 0.2 0.062 13.7 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KII94433.1 - 4.2e-05 23.2 0.1 0.5 9.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KII94433.1 - 8.1e-05 22.6 4.2 0.058 13.2 0.1 4.3 2 2 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII94433.1 - 0.00015 21.4 1.1 0.24 11.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KII94433.1 - 0.00018 22.1 0.1 0.00018 22.1 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KII94433.1 - 0.0017 18.7 0.7 0.88 9.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII94433.1 - 0.0041 16.6 0.2 3.6 7.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 KII94433.1 - 0.0063 16.6 0.7 0.75 9.9 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_11 PF13086.6 KII94433.1 - 0.013 15.3 0.1 0.088 12.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KII94433.1 - 0.016 15.1 0.3 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 KII94433.1 - 0.021 14.8 0.2 6.5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 KII94433.1 - 0.029 14.4 1.5 0.14 12.3 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 KII94433.1 - 0.032 13.9 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KII94433.1 - 0.035 14.5 0.3 0.61 10.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KII94433.1 - 0.036 13.1 0.2 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KII94433.1 - 0.12 11.8 0.2 17 4.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KII94433.1 - 0.12 12.1 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Adeno_IVa2 PF02456.15 KII94433.1 - 0.16 10.7 0.4 1.2 7.9 0.0 2.3 3 0 0 3 3 3 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 KII94433.1 - 2.8 8.0 7.1 4.2 7.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family MFS_1 PF07690.16 KII94434.1 - 1.5e-15 57.0 28.1 1.5e-15 57.0 28.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KII94434.1 - 4.8e-12 45.8 6.9 4.8e-12 45.8 6.9 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 GYF PF02213.16 KII94435.1 - 9.1e-17 60.5 0.5 2.3e-16 59.2 0.5 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KII94435.1 - 0.031 14.1 2.3 0.032 14.0 0.2 2.2 2 0 0 2 2 2 0 GYF domain 2 PGA2 PF07543.12 KII94435.1 - 1.7 8.6 4.4 3.9 7.5 4.4 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Acatn PF13000.7 KII94436.1 - 8.3e-153 509.8 27.3 3.1e-74 250.4 16.9 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.22 KII94437.1 - 7.3e-57 193.1 0.0 9.1e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 KII94438.1 - 4.8e-42 143.5 0.0 7.7e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KII94438.1 - 2.7e-28 97.7 0.3 7.8e-28 96.3 0.3 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KII94438.1 - 1.9e-24 85.5 8.5 3.7e-24 84.6 8.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KII94438.1 - 2e-07 30.7 0.0 5.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KII94438.1 - 6.5e-06 26.6 0.2 4.1e-05 24.0 0.1 2.2 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 KII94438.1 - 6.8e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KII94438.1 - 1.6e-05 25.2 1.0 0.021 15.1 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KII94438.1 - 1.8e-05 24.8 0.0 5.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KII94438.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 KII94438.1 - 6e-05 23.1 0.2 0.00017 21.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KII94438.1 - 0.0011 19.1 0.0 0.0032 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 KII94438.1 - 0.0011 18.2 0.2 0.0022 17.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 KII94438.1 - 0.0012 18.1 0.0 0.0059 15.8 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KII94438.1 - 0.0015 18.7 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KII94438.1 - 0.0016 19.0 0.1 0.005 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KII94438.1 - 0.002 17.9 0.1 0.0053 16.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KII94438.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KII94438.1 - 0.0074 15.9 0.2 0.75 9.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 KII94438.1 - 0.01 15.3 0.0 1.7 8.1 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 KII94438.1 - 0.016 15.6 0.0 0.046 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KII94438.1 - 0.021 14.2 0.2 4.6 6.5 0.0 2.3 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 KII94438.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KII94438.1 - 0.048 13.1 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KII94438.1 - 0.056 13.0 0.0 0.18 11.3 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KII94438.1 - 0.064 13.2 0.0 0.37 10.7 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KII94438.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KII94438.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 KII94438.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain VirE PF05272.11 KII94438.1 - 0.14 11.8 0.4 36 4.0 0.1 3.1 3 1 1 4 4 4 0 Virulence-associated protein E Viral_helicase1 PF01443.18 KII94438.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KII94438.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KII94438.1 - 0.22 11.4 2.4 1.4 8.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea MAGI_u5 PF16666.5 KII94440.1 - 0.15 12.2 3.5 0.18 12.0 3.5 1.2 1 0 0 1 1 1 0 Unstructured region on MAGI TIP120 PF08623.10 KII94441.1 - 1.3e-57 194.2 0.0 4.7e-56 189.2 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KII94441.1 - 7.2e-17 61.6 15.3 0.00058 20.2 0.1 8.6 7 1 1 8 8 8 4 HEAT repeats HEAT PF02985.22 KII94441.1 - 2.1e-14 52.4 22.4 0.027 14.7 0.0 12.9 13 0 0 13 13 12 2 HEAT repeat HEAT_EZ PF13513.6 KII94441.1 - 2.8e-12 46.9 31.9 0.21 12.1 0.8 12.8 13 1 2 15 15 13 4 HEAT-like repeat CLASP_N PF12348.8 KII94441.1 - 4e-09 36.4 2.0 0.021 14.4 0.0 6.5 5 1 1 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 KII94441.1 - 3.5e-08 32.5 8.1 0.47 9.0 0.1 6.2 4 2 0 5 5 5 2 Adaptin N terminal region Tti2 PF10521.9 KII94441.1 - 4.7e-06 26.3 4.6 0.71 9.4 0.0 5.7 6 0 0 6 6 6 1 Tti2 family Cnd1 PF12717.7 KII94441.1 - 4.7e-06 26.7 6.9 1.6 8.8 0.2 6.5 6 2 1 8 8 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KII94441.1 - 8.6e-06 26.3 0.1 5.2 7.7 0.1 6.4 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KII94441.1 - 1.3e-05 25.3 0.9 0.043 14.0 0.0 5.4 4 2 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 KII94441.1 - 1.7e-05 24.8 0.4 0.017 15.0 0.0 4.9 6 0 0 6 6 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KII94441.1 - 0.00089 18.5 31.6 0.39 9.8 0.1 6.5 4 2 2 6 6 6 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 KII94441.1 - 0.002 18.3 1.5 9.3 6.3 0.0 4.9 6 0 0 6 6 6 0 Parkin co-regulated protein MMS19_N PF14500.6 KII94441.1 - 0.0026 17.4 7.1 18 4.8 0.0 6.6 7 2 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II Telomere_reg-2 PF10193.9 KII94441.1 - 0.0034 17.8 0.9 0.61 10.6 0.0 3.9 3 0 0 3 3 3 1 Telomere length regulation protein Cnd3 PF12719.7 KII94441.1 - 0.007 15.6 1.3 3.9 6.6 0.0 4.8 5 1 1 6 6 6 1 Nuclear condensing complex subunits, C-term domain V-ATPase_H_C PF11698.8 KII94441.1 - 0.011 15.9 0.4 1.6 8.8 0.2 4.2 4 0 0 4 4 3 0 V-ATPase subunit H DUF4042 PF13251.6 KII94441.1 - 0.024 14.4 7.5 13 5.5 0.0 6.4 8 0 0 8 8 8 0 Domain of unknown function (DUF4042) TAF6_C PF07571.13 KII94441.1 - 0.041 14.2 0.1 12 6.3 0.0 4.5 5 0 0 5 5 4 0 TAF6 C-terminal HEAT repeat domain DNA_Packaging PF11053.8 KII94441.1 - 0.081 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme GCIP PF13324.6 KII94441.1 - 0.099 12.2 1.5 2 8.0 0.3 3.0 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF4611 PF15387.6 KII94441.1 - 0.1 12.8 3.4 0.16 12.2 1.6 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) RPN6_N PF18055.1 KII94441.1 - 0.17 12.2 0.4 9.1 6.7 0.0 3.3 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Arm PF00514.23 KII94441.1 - 0.33 11.1 6.2 23 5.2 0.0 5.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat REF PF05755.12 KII94441.1 - 0.35 10.6 2.5 0.31 10.8 0.4 2.0 2 0 0 2 2 1 0 Rubber elongation factor protein (REF) API5 PF05918.11 KII94441.1 - 0.47 9.2 2.1 8.6 5.0 0.6 2.9 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Sec7_N PF12783.7 KII94441.1 - 0.7 9.8 7.9 3.9 7.4 0.1 5.3 5 2 1 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Asp PF00026.23 KII94442.1 - 4.3e-50 170.9 14.4 1.4e-49 169.2 14.4 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII94442.1 - 5.2e-10 39.9 7.9 3e-05 24.3 0.4 3.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII94442.1 - 0.00078 20.0 5.7 0.0022 18.6 0.7 2.6 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 KII94442.1 - 0.055 13.2 0.4 1.2 8.8 0.4 2.5 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KII94442.1 - 0.6 10.7 2.8 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Dynactin_p62 PF05502.13 KII94443.1 - 1 8.0 4.6 2 7.1 4.6 1.4 1 0 0 1 1 1 0 Dynactin p62 family UPF0370 PF13980.6 KII94443.1 - 1.5 8.9 3.9 3.4 7.8 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF1764 PF08576.10 KII94443.1 - 5.7 7.9 10.3 33 5.5 4.9 3.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) DAO PF01266.24 KII94444.1 - 6e-34 118.2 5.0 7.9e-34 117.8 5.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KII94444.1 - 0.048 13.9 0.2 0.17 12.1 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribonuclease_3 PF00636.26 KII94446.1 - 0.00046 20.8 0.0 0.0015 19.2 0.0 1.8 1 1 1 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KII94446.1 - 0.0018 18.5 0.0 0.89 9.7 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like MutS_V PF00488.21 KII94447.1 - 1.3e-55 188.3 0.8 5.3e-55 186.4 0.0 2.3 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.18 KII94447.1 - 2.5e-32 112.7 7.1 3.3e-32 112.3 3.7 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KII94447.1 - 2.2e-06 27.9 0.1 6.4e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 KII94447.1 - 2.9e-05 24.4 0.0 9.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KII94447.1 - 0.079 12.5 0.0 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain YL1 PF05764.13 KII94448.1 - 7.1e-37 127.8 20.5 9.3e-37 127.4 20.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 KII94448.1 - 1.4e-12 47.1 0.2 2.3e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CSRNP_N PF16019.5 KII94448.1 - 4.4 7.1 11.1 9.9 6.0 2.5 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus L51_S25_CI-B8 PF05047.16 KII94449.1 - 9.1e-09 35.1 0.2 1.6e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ER-remodelling PF14755.6 KII94449.1 - 0.018 15.4 0.5 0.026 14.8 0.5 1.2 1 0 0 1 1 1 0 Intracellular membrane remodeller GET2 PF08690.10 KII94450.1 - 4.4e-08 33.2 0.0 2e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 ArfGap PF01412.18 KII94451.1 - 1.8e-40 137.7 0.1 2.5e-40 137.2 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Nucleoporin_FG PF13634.6 KII94451.1 - 0.33 11.8 14.7 4.8 8.1 14.6 2.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region HflK_N PF12221.8 KII94451.1 - 1.5 8.9 10.4 9.2 6.4 0.1 3.7 2 1 0 2 2 2 0 Bacterial membrane protein N terminal Peptidase_M1 PF01433.20 KII94452.1 - 1e-36 126.6 0.0 1.4e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KII94452.1 - 1.2e-31 109.1 0.0 2.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KII94452.1 - 6.7e-20 72.0 0.0 1.1e-19 71.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KII94452.1 - 0.17 12.3 2.6 4.5 7.7 2.6 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF515 PF04415.12 KII94453.1 - 4.6 5.5 6.0 6.4 5.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Ost5 PF05251.12 KII94454.1 - 3.5e-20 72.0 10.6 4.1e-20 71.8 10.6 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF3792 PF12670.7 KII94454.1 - 0.026 14.7 2.8 0.031 14.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) TB2_DP1_HVA22 PF03134.19 KII94455.1 - 4.5e-27 93.8 7.3 8.2e-27 93.0 7.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MFS_1 PF07690.16 KII94456.1 - 6.7e-15 54.9 30.6 6.7e-15 54.9 30.6 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KII94456.1 - 5.3e-09 36.0 8.5 5.3e-09 36.0 8.5 2.5 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Col_cuticle_N PF01484.17 KII94456.1 - 0.00047 20.2 4.2 0.65 10.1 0.1 3.6 3 0 0 3 3 3 3 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 KII94457.1 - 3.6e-61 206.8 0.0 1e-60 205.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94457.1 - 8.4e-29 100.6 0.2 4.4e-20 72.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KII94457.1 - 9.8e-05 21.8 0.3 0.012 14.9 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KII94457.1 - 0.003 17.5 0.5 0.034 14.1 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII94457.1 - 0.0059 15.6 0.0 0.018 14.0 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KII94457.1 - 0.0066 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII94457.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Spindle_Spc25 PF08234.12 KII94458.1 - 2.1e-22 79.1 0.1 6.8e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KII94458.1 - 0.003 16.5 9.7 0.0039 16.1 9.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_N PF10481.9 KII94458.1 - 0.0051 16.5 7.2 0.19 11.3 1.4 2.1 1 1 0 2 2 2 2 Cenp-F N-terminal domain FapA PF03961.13 KII94458.1 - 0.09 11.4 6.3 0.12 10.9 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4200 PF13863.6 KII94458.1 - 0.13 12.7 15.1 0.46 10.9 15.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 KII94458.1 - 0.26 11.3 5.7 1.9 8.5 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 KII94458.1 - 0.29 10.5 4.5 0.38 10.1 4.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF5401 PF17380.2 KII94458.1 - 0.55 8.2 13.5 0.66 8.0 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Atg14 PF10186.9 KII94458.1 - 0.64 9.0 10.7 0.86 8.6 10.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 KII94458.1 - 1.6 8.9 10.6 2.5 8.2 10.6 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KII94458.1 - 2.8 8.5 16.4 3.9 8.0 10.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 KII94458.1 - 3.3 7.9 8.4 0.49 10.5 4.2 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.14 KII94458.1 - 3.7 7.3 8.6 6.8 6.5 8.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tho2 PF11262.8 KII94458.1 - 5.9 6.0 9.6 2.2 7.4 5.1 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Ribosomal_L4 PF00573.22 KII94459.1 - 0.0018 18.0 0.2 0.0026 17.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PGI PF00342.19 KII94461.1 - 4.5e-18 65.1 0.0 5.4e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF89 PF01937.19 KII94461.1 - 2.2e-10 40.0 0.0 2.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Retrotrans_gag PF03732.17 KII94468.1 - 0.063 13.6 0.6 0.13 12.6 0.3 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein Sporozoite_P67 PF05642.11 KII94470.1 - 0.53 8.3 4.0 0.74 7.8 4.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HalX PF08663.10 KII94471.1 - 0.012 15.9 12.6 0.039 14.3 0.0 3.6 3 1 0 3 3 3 0 HalX domain DHR10 PF18595.1 KII94471.1 - 0.036 14.1 8.6 1.2 9.2 0.5 3.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Taxilin PF09728.9 KII94471.1 - 0.12 11.6 0.2 0.18 11.0 0.2 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Phasin_2 PF09361.10 KII94471.1 - 0.16 12.3 3.9 2 8.7 0.2 2.5 2 1 0 2 2 2 0 Phasin protein DUF4404 PF14357.6 KII94471.1 - 1.2 9.9 8.0 0.51 11.0 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Plavaka PF18759.1 KII94473.1 - 3e-18 66.1 1.7 3e-18 66.1 1.7 1.6 2 0 0 2 2 2 1 Plavaka transposase Ubiquitin_2 PF14560.6 KII94473.1 - 0.018 15.5 1.0 2.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain SopE_GEF PF07487.13 KII94473.1 - 0.048 13.8 0.0 0.19 11.9 0.0 1.7 1 1 1 2 2 2 0 SopE GEF domain DUF569 PF04601.13 KII94473.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF569) DUF3109 PF11307.8 KII94474.1 - 0.0067 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) Asp_protease_2 PF13650.6 KII94476.1 - 4.8e-05 23.9 0.0 0.00018 22.1 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KII94476.1 - 0.0008 19.9 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KII94476.1 - 0.0023 17.7 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 KII94476.1 - 0.042 13.6 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Peptidase_A2B PF12384.8 KII94476.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase COG5 PF10392.9 KII94479.1 - 0.13 12.4 0.9 0.22 11.7 0.9 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Cep57_CLD_2 PF14197.6 KII94479.1 - 0.44 10.7 3.9 0.94 9.6 3.8 1.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 HBS1_N PF08938.10 KII94482.1 - 1.4 9.2 6.9 2.5 8.5 6.9 1.3 1 0 0 1 1 1 0 HBS1 N-terminus FmrO PF07091.11 KII94483.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ERM PF00769.19 KII94484.1 - 0.0099 15.7 9.5 0.014 15.2 9.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF3340 PF11818.8 KII94484.1 - 0.043 14.0 6.9 0.074 13.2 6.9 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) CENP-H PF05837.12 KII94484.1 - 1.1 9.7 6.8 2 8.8 6.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_13 PF13166.6 KII94484.1 - 5.5 5.5 8.2 7.7 5.0 8.2 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.21 KII94485.1 - 1.9e-45 155.1 1.4 2.2e-45 154.9 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2 PF00096.26 KII94487.1 - 1.1e-05 25.6 15.0 2.1e-05 24.7 2.0 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII94487.1 - 0.00051 20.4 2.3 0.00051 20.4 2.3 2.5 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 KII94487.1 - 0.0058 16.4 1.4 0.015 15.0 1.4 1.7 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-Dof PF02701.15 KII94487.1 - 0.011 15.8 0.8 0.022 14.9 0.8 1.5 1 0 0 1 1 1 0 Dof domain, zinc finger zf-C2H2_4 PF13894.6 KII94487.1 - 0.013 16.3 1.0 0.013 16.3 1.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII94487.1 - 0.22 11.6 3.1 2 8.5 3.1 2.6 1 1 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KII94487.1 - 0.31 11.5 0.3 0.31 11.5 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KII94487.1 - 2.2 9.0 5.5 2.4 8.9 0.8 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain Metallophos PF00149.28 KII94489.1 - 2.2e-35 123.0 0.2 3.2e-35 122.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KII94489.1 - 0.0072 16.8 0.4 0.014 15.8 0.4 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KII94489.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain ABC_tran PF00005.27 KII94490.1 - 1.8e-46 158.0 0.0 1.3e-21 77.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KII94490.1 - 3.4e-20 71.9 5.1 3.4e-20 71.9 5.1 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KII94490.1 - 9.4e-16 58.5 1.4 0.0019 18.1 0.1 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII94490.1 - 1.4e-09 37.7 2.8 0.19 11.1 0.1 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII94490.1 - 5.5e-09 36.8 6.4 0.002 18.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 KII94490.1 - 7.6e-09 35.2 0.2 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KII94490.1 - 1.3e-07 32.1 0.0 0.0011 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KII94490.1 - 2.6e-06 27.5 0.7 0.012 15.5 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 KII94490.1 - 1.8e-05 24.7 8.7 0.11 12.2 0.8 4.5 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KII94490.1 - 2.8e-05 24.1 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KII94490.1 - 4.8e-05 23.4 0.1 0.051 13.7 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KII94490.1 - 0.00053 20.2 0.0 0.85 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KII94490.1 - 0.00055 19.7 0.1 0.079 12.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KII94490.1 - 0.00095 19.7 0.1 2.6 8.6 0.0 3.8 3 1 1 4 4 4 1 AAA domain DUF87 PF01935.17 KII94490.1 - 0.0012 19.0 3.1 0.77 9.8 0.1 3.7 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_24 PF13479.6 KII94490.1 - 0.0023 17.7 0.3 3.4 7.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KII94490.1 - 0.0033 17.5 11.5 0.14 12.2 0.1 4.5 2 2 1 3 3 3 1 Dynamin family AAA_22 PF13401.6 KII94490.1 - 0.0039 17.5 0.1 4 7.7 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KII94490.1 - 0.0044 17.3 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KII94490.1 - 0.0086 15.5 0.2 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 KII94490.1 - 0.0097 16.3 3.1 8.1 6.9 0.0 3.4 3 0 0 3 3 3 0 RNA helicase KAP_NTPase PF07693.14 KII94490.1 - 0.012 14.9 0.1 0.88 8.7 0.1 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_27 PF13514.6 KII94490.1 - 0.012 15.2 0.2 1.8 8.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KII94490.1 - 0.013 15.5 0.2 6.9 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KII94490.1 - 0.014 14.6 0.0 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain G-alpha PF00503.20 KII94490.1 - 0.021 14.0 0.4 4.1 6.4 0.0 3.0 3 1 0 3 3 3 0 G-protein alpha subunit AAA_25 PF13481.6 KII94490.1 - 0.029 14.0 0.5 20 4.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 KII94490.1 - 0.03 14.7 0.6 28 5.2 0.0 4.0 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KII94490.1 - 0.043 14.0 0.0 18 5.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KII94490.1 - 0.044 13.0 0.4 1.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin MukB PF04310.12 KII94490.1 - 0.047 13.5 0.5 0.99 9.2 0.0 2.8 3 0 0 3 3 2 0 MukB N-terminal MeaB PF03308.16 KII94490.1 - 0.065 12.2 0.1 13 4.7 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KII94490.1 - 0.091 12.7 2.3 2.8 7.8 0.1 3.1 4 0 0 4 4 3 0 NTPase SbcCD_C PF13558.6 KII94490.1 - 0.098 12.9 0.1 4.7 7.5 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.6 KII94490.1 - 0.12 12.8 1.2 21 5.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain DivIC PF04977.15 KII94490.1 - 1.7 8.4 6.0 8.6 6.2 3.2 2.6 2 0 0 2 2 2 0 Septum formation initiator zf-MYND PF01753.18 KII94491.1 - 6.5e-12 45.3 28.2 3.6e-11 43.0 11.4 3.1 3 0 0 3 3 3 2 MYND finger Meleagrin PF08189.11 KII94491.1 - 0.65 9.7 5.0 2.2 8.1 5.0 1.9 1 0 0 1 1 1 0 Meleagrin/Cygnin family DUF3106 PF11304.8 KII94493.1 - 0.16 12.5 0.1 5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) F-box PF00646.33 KII94494.1 - 0.056 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 F-box domain Glyco_transf_52 PF07922.11 KII94494.1 - 0.12 11.6 0.3 0.22 10.8 0.1 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 52 Pkinase_fungal PF17667.1 KII94495.1 - 1.5e-57 195.2 0.0 7.9e-31 107.2 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KII94495.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KII94495.1 - 0.013 15.4 0.1 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KII94496.1 - 4.8e-84 282.5 2.8 7.1e-83 278.6 0.1 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 KII94496.1 - 0.0028 17.0 0.1 0.0053 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Chol_subst-bind PF09129.11 KII94496.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Pkinase_Tyr PF07714.17 KII94496.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII94497.1 - 0.006 15.4 0.0 0.0097 14.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KII94498.1 - 3.4e-24 85.4 0.0 4.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF4449 PF14613.6 KII94499.1 - 0.013 15.6 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Lyase_1 PF00206.20 KII94499.1 - 0.049 13.0 0.9 0.091 12.1 0.9 1.3 1 0 0 1 1 1 0 Lyase DUF2497 PF10691.9 KII94503.1 - 0.047 14.1 0.4 0.19 12.2 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) Flexi_CP PF00286.20 KII94503.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 Viral coat protein FANC_SAP PF18081.1 KII94503.1 - 0.28 11.4 2.7 0.35 11.1 0.3 2.5 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain MID_MedPIWI PF18296.1 KII94503.1 - 0.81 9.4 4.6 1.4 8.7 4.6 1.3 1 0 0 1 1 1 0 MID domain of medPIWI CCDC106 PF15794.5 KII94503.1 - 3.1 7.5 12.9 5 6.8 12.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Mlh1_C PF16413.5 KII94506.1 - 0.15 11.4 1.1 5.1 6.4 0.1 2.1 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus Orexin_rec2 PF03827.13 KII94507.1 - 4 7.5 5.7 98 3.1 0.0 3.3 3 0 0 3 3 3 0 Orexin receptor type 2 ER-remodelling PF14755.6 KII94508.1 - 0.21 11.9 5.3 0.3 11.4 5.3 1.3 1 0 0 1 1 1 0 Intracellular membrane remodeller Pkinase_fungal PF17667.1 KII94510.1 - 2.9e-49 167.9 0.0 9.4e-48 163.0 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII94510.1 - 7.4e-07 28.8 0.2 1.6e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 KII94510.1 - 0.0094 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KII94510.1 - 0.04 13.8 0.4 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Chordopox_RPO7 PF05864.12 KII94513.1 - 0.052 13.8 2.1 0.62 10.4 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TerY_C PF15616.6 KII94513.1 - 0.085 13.0 0.2 0.085 13.0 0.2 1.5 2 0 0 2 2 2 0 TerY-C metal binding domain TRI5 PF06330.11 KII94514.1 - 7.6e-20 71.1 0.0 1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) KNOX2 PF03791.13 KII94514.1 - 0.28 10.7 1.2 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 KNOX2 domain TRI5 PF06330.11 KII94515.1 - 1.5e-23 83.3 0.0 2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Pkinase_fungal PF17667.1 KII94516.1 - 4.9e-77 259.4 0.5 1.5e-37 129.4 0.0 2.8 2 1 1 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KII94516.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII94516.1 - 0.0053 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII94516.1 - 0.041 13.2 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KII94516.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4661 PF15576.6 KII94516.1 - 0.34 10.8 4.4 0.62 9.9 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) N6-adenineMlase PF10237.9 KII94517.1 - 1e-37 129.4 0.0 1.2e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase F-box-like PF12937.7 KII94518.1 - 1.4e-05 24.9 0.2 4e-05 23.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_2 PF00891.18 KII94520.1 - 3.2e-26 91.9 0.0 8.1e-24 84.1 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KII94520.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII94520.1 - 0.0041 17.0 0.0 0.0077 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII94520.1 - 0.013 16.2 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KII94521.1 - 4.8e-27 94.6 0.0 7.1e-26 90.8 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KII94521.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KII94521.1 - 0.046 14.5 0.0 0.09 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DprA_WH PF17782.1 KII94521.1 - 0.13 12.4 0.7 0.33 11.1 0.7 1.7 1 0 0 1 1 1 0 DprA winged helix domain Methyltransf_23 PF13489.6 KII94521.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.22 KII94522.1 - 4.8e-24 84.7 0.8 9e-24 83.8 0.8 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Phosphorylase PF00343.20 KII94522.1 - 0.023 13.0 1.0 0.027 12.8 1.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase TnpV PF14198.6 KII94522.1 - 0.027 14.4 0.3 0.05 13.6 0.3 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV F-box-like PF12937.7 KII94523.1 - 1.1e-05 25.2 0.6 1.1e-05 25.2 0.6 2.3 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 KII94524.1 - 1.8e-07 30.7 2.9 0.23 11.7 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KII94524.1 - 3e-06 26.8 0.1 1.4 8.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.31 KII94524.1 - 2.6e-05 24.0 1.4 7.1e-05 22.6 0.0 2.5 3 0 0 3 3 3 1 UBA/TS-N domain TPR_16 PF13432.6 KII94524.1 - 0.0033 18.0 0.6 0.0033 18.0 0.6 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 KII94524.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain F-box-like PF12937.7 KII94525.1 - 3.5e-05 23.6 0.1 0.00013 21.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII94525.1 - 4.4 7.9 6.4 50 4.5 0.6 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF3143 PF11341.8 KII94527.1 - 0.04 14.3 0.1 1 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) tRNA-synt_1g PF09334.11 KII94529.1 - 3.3e-87 292.8 0.0 1.5e-84 284.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KII94529.1 - 4.1e-17 61.7 1.6 8.2e-10 37.6 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KII94529.1 - 2.5e-09 36.9 0.0 0.00098 18.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KII94529.1 - 0.064 12.2 0.0 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) PBP PF01161.20 KII94530.1 - 5.9e-12 46.0 0.0 9.5e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3143 PF11341.8 KII94531.1 - 0.041 14.2 0.1 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) Lipase_GDSL_2 PF13472.6 KII94535.1 - 1.2e-05 25.8 0.0 1.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KII94535.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Mg_chelatase PF01078.21 KII94537.1 - 0.2 11.0 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PLA2_B PF01735.18 KII94539.1 - 4.2e-102 342.1 0.0 5.3e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TMEM108 PF15759.5 KII94540.1 - 3.4 6.6 17.3 4.1 6.3 17.3 1.1 1 0 0 1 1 1 0 TMEM108 family Coatomer_WDAD PF04053.14 KII94541.1 - 4.6e-152 507.1 0.0 9.4e-152 506.1 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KII94541.1 - 2.1e-38 129.6 8.3 1.3e-07 32.1 0.0 8.7 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94541.1 - 5.3e-09 36.3 0.1 0.005 17.1 0.0 5.8 4 3 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KII94541.1 - 0.00044 20.3 0.7 5.7 7.0 0.0 4.3 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 KII94541.1 - 0.0036 16.0 2.1 0.4 9.3 0.1 3.9 1 1 3 4 4 4 1 Nucleoporin Nup120/160 LigD_N PF13298.6 KII94541.1 - 0.1 12.9 0.0 4 7.8 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) AA_permease PF00324.21 KII94543.1 - 5.1e-125 417.8 43.6 5.7e-125 417.6 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII94543.1 - 1.7e-45 155.7 49.2 2.1e-45 155.3 49.2 1.1 1 0 0 1 1 1 1 Amino acid permease SPC25 PF06703.11 KII94543.1 - 0.055 13.2 0.0 0.055 13.2 0.0 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) p450 PF00067.22 KII94544.1 - 4.6e-66 223.5 0.0 5.7e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.15 KII94548.1 - 4.8e-234 777.8 0.0 6.2e-234 777.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KII94548.1 - 4.4e-109 365.6 0.0 1.1e-108 364.3 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KII94548.1 - 2.7e-18 65.9 0.0 2.8e-13 49.8 0.1 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KII94548.1 - 3.9e-16 58.7 0.2 1.2e-15 57.1 0.2 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KII94548.1 - 1.3e-13 51.4 0.0 5.4e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KII94548.1 - 4.6e-12 46.3 2.5 1.1e-11 45.0 2.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KII94548.1 - 2.5e-08 33.9 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KII94548.1 - 0.0048 16.4 0.0 0.032 13.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 ARS2 PF04959.13 KII94548.1 - 2 8.7 6.2 5.3 7.4 6.2 1.7 1 0 0 1 1 1 0 Arsenite-resistance protein 2 His_Phos_2 PF00328.22 KII94550.1 - 1.5e-55 189.1 0.0 2.2e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3156 PF11354.8 KII94550.1 - 0.13 12.2 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) NUDIX PF00293.28 KII94552.1 - 1.3e-11 44.6 0.0 4.4e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain DUF4231 PF14015.6 KII94553.1 - 1.2 9.6 10.4 0.18 12.3 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Xan_ur_permease PF00860.20 KII94554.1 - 2.8e-61 207.4 30.6 2.8e-61 207.4 30.6 2.3 2 1 0 2 2 2 1 Permease family Phage_holin_5_1 PF06946.11 KII94554.1 - 2.9 8.4 5.3 0.6 10.5 0.2 2.6 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 F-box PF00646.33 KII94555.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII94555.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 KII94555.1 - 0.059 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 F-box Osteopontin PF00865.18 KII94555.1 - 0.23 10.9 11.5 0.39 10.2 11.5 1.3 1 0 0 1 1 1 0 Osteopontin RhgB_N PF09284.10 KII94556.1 - 3e-104 348.0 2.6 4.5e-104 347.4 2.6 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KII94556.1 - 2.6e-43 147.8 0.1 7.2e-43 146.3 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KII94556.1 - 1.2e-16 60.3 5.1 1.4e-16 60.0 3.3 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KII94556.1 - 0.13 12.6 5.8 0.055 13.7 2.1 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Hist_deacetyl PF00850.19 KII94557.1 - 1.8e-81 274.0 0.1 2.3e-81 273.6 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain BUD22 PF09073.10 KII94557.1 - 0.036 13.4 2.4 0.048 13.0 2.4 1.1 1 0 0 1 1 1 0 BUD22 Utp14 PF04615.13 KII94557.1 - 0.038 12.6 3.1 0.05 12.2 3.1 1.1 1 0 0 1 1 1 0 Utp14 protein DUF3245 PF11595.8 KII94557.1 - 0.58 10.6 6.0 1 9.8 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Pkinase_Tyr PF07714.17 KII94558.1 - 2.5e-32 112.2 0.0 2.8e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII94558.1 - 4.5e-25 88.5 0.0 5.5e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KII94558.1 - 0.031 13.1 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KII94558.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Tim17 PF02466.19 KII94559.1 - 3e-05 24.4 4.9 3.4 8.1 0.1 4.5 3 2 1 4 4 4 3 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 KII94559.1 - 0.069 13.7 0.2 3.8 8.1 0.1 2.8 2 1 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 Ribosomal_L7Ae PF01248.26 KII94560.1 - 6.2e-27 93.2 2.2 7.7e-27 92.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.32 KII94561.1 - 3.1e-23 81.6 23.1 1.1e-07 32.4 1.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94561.1 - 3.3e-13 49.7 0.6 4.2e-06 27.0 0.0 3.8 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII94561.1 - 0.00086 18.7 0.0 0.2 10.9 0.0 2.8 4 0 0 4 4 4 2 WD40-like domain eIF2A PF08662.11 KII94561.1 - 0.0041 17.0 0.0 0.48 10.3 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KII94561.1 - 0.0044 16.0 0.1 7.9 5.3 0.0 3.3 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KII94561.1 - 0.019 13.3 0.1 0.038 12.3 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz MMS1_N PF10433.9 KII94561.1 - 0.039 12.6 0.0 0.26 9.9 0.0 2.0 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term VID27 PF08553.10 KII94561.1 - 0.041 12.9 0.0 6.1 5.8 0.0 2.1 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain IKI3 PF04762.12 KII94561.1 - 0.33 8.9 0.4 0.76 7.7 0.0 1.7 3 0 0 3 3 3 0 IKI3 family PD40 PF07676.12 KII94561.1 - 5.2 7.1 12.6 1.5e+02 2.4 0.0 6.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Pox_A14 PF05767.12 KII94563.1 - 0.0011 19.1 1.4 0.015 15.5 0.2 2.4 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Trp_oprn_chp PF09534.10 KII94563.1 - 0.024 14.4 1.1 0.045 13.5 0.2 1.8 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tmemb_40 PF10160.9 KII94563.1 - 0.043 13.3 5.2 0.046 13.2 0.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein DUF4199 PF13858.6 KII94563.1 - 0.057 13.8 4.3 0.52 10.7 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) TctB PF07331.11 KII94563.1 - 0.091 13.0 8.1 0.21 11.9 8.1 1.6 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF975 PF06161.11 KII94563.1 - 0.093 12.5 3.0 0.15 11.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF2207 PF09972.9 KII94563.1 - 6.2 5.5 6.6 3.7 6.2 4.8 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) WW PF00397.26 KII94564.1 - 0.017 15.2 2.2 0.086 13.0 0.4 2.5 2 0 0 2 2 2 0 WW domain Clathrin PF00637.20 KII94565.1 - 8e-27 93.9 0.1 1.8e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.9 KII94565.1 - 0.00031 21.0 0.3 0.011 16.0 0.1 2.8 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 Sigma70_ner PF04546.13 KII94565.1 - 0.013 15.4 7.2 0.026 14.4 7.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-RING_2 PF13639.6 KII94565.1 - 0.031 14.6 1.5 0.21 12.0 0.3 2.5 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.32 KII94565.1 - 0.05 14.5 0.1 0.24 12.4 0.1 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat Vps39_2 PF10367.9 KII94565.1 - 0.071 13.6 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 KII94565.1 - 0.076 13.0 0.8 0.3 11.1 0.8 2.1 1 1 0 1 1 1 0 zinc-RING finger domain PQQ_2 PF13360.6 KII94565.1 - 0.086 12.4 0.1 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain Zn_ribbon_17 PF17120.5 KII94565.1 - 0.21 11.2 1.8 0.22 11.2 0.3 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MPP6 PF10175.9 KII94565.1 - 0.96 9.9 4.7 2 8.9 4.7 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 YL1 PF05764.13 KII94565.1 - 1.4 9.0 9.7 2.3 8.3 9.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Trypan_PARP PF05887.11 KII94565.1 - 3.2 7.7 7.2 6.2 6.8 7.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 KII94565.1 - 4.4 5.3 22.8 6.9 4.6 22.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 KII94565.1 - 8.9 4.5 10.4 13 3.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 KII94565.1 - 8.9 6.0 18.4 18 5.0 18.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein fn3_2 PF16893.5 KII94568.1 - 1.7e-38 130.6 0.5 3.9e-38 129.5 0.2 1.8 2 0 0 2 2 2 1 Fibronectin type III domain CHS5_N PF16892.5 KII94568.1 - 6.6e-19 67.6 0.3 1.7e-18 66.3 0.2 1.8 2 0 0 2 2 2 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KII94568.1 - 2.4e-06 27.8 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KII94568.1 - 0.0011 18.9 0.1 0.009 15.9 0.1 2.2 1 1 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KII94568.1 - 0.0055 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KII94568.1 - 0.0057 17.0 0.3 0.031 14.6 0.3 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Pkinase PF00069.25 KII94569.1 - 2.8e-66 223.6 0.0 3.6e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII94569.1 - 1.4e-30 106.5 0.0 3.4e-30 105.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KII94569.1 - 0.0081 16.1 0.3 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KII94569.1 - 0.031 13.2 0.0 0.061 12.3 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain AF-4 PF05110.13 KII94570.1 - 0.023 12.8 4.6 0.031 12.4 4.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein 7tm_7 PF08395.12 KII94570.1 - 0.096 11.9 1.1 0.17 11.0 1.1 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF1218 PF06749.12 KII94570.1 - 1.9 9.1 6.9 0.27 11.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Helicase_C PF00271.31 KII94571.1 - 1.4e-12 48.0 0.0 3e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII94571.1 - 0.12 12.1 0.1 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase BTB PF00651.31 KII94573.1 - 0.00035 20.8 0.5 0.0011 19.1 0.4 1.9 2 1 0 2 2 2 1 BTB/POZ domain Myb_DNA-binding PF00249.31 KII94575.1 - 5.6e-11 42.4 0.8 1.2e-10 41.4 0.8 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII94575.1 - 8.6e-09 35.5 0.1 1.7e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BSP_II PF05432.11 KII94575.1 - 0.015 15.0 4.4 0.21 11.3 0.6 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.14 KII94575.1 - 3.1 7.5 16.7 1.8 8.3 7.7 2.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3824 PF12868.7 KII94575.1 - 3.4 8.3 38.5 0.46 11.1 4.2 4.0 3 0 0 3 3 3 0 Domain of unknwon function (DUF3824) FAM176 PF14851.6 KII94576.1 - 8.1 6.1 6.6 0.64 9.7 0.8 2.0 2 0 0 2 2 2 0 FAM176 family Helicase_C PF00271.31 KII94577.1 - 5.7e-17 62.1 0.0 1.7e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII94577.1 - 5.9e-15 55.5 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII94577.1 - 2.2e-09 37.6 0.0 3.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KII94577.1 - 0.0014 18.4 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KII94577.1 - 0.0098 16.2 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiQ PF02361.16 KII94578.1 - 0.16 11.5 6.0 0.4 10.3 0.2 2.2 2 0 0 2 2 2 0 Cobalt transport protein Abhydrolase_1 PF00561.20 KII94579.1 - 1.1e-19 71.1 0.2 1.3e-18 67.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII94579.1 - 6.4e-18 66.2 5.7 6.4e-18 66.2 5.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII94579.1 - 6e-15 55.2 0.2 3.3e-14 52.7 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KII94579.1 - 6.1e-07 29.5 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.7 KII94579.1 - 0.0014 18.4 0.0 1.5 8.5 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.18 KII94579.1 - 0.0044 16.6 0.0 0.028 14.0 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KII94579.1 - 0.0074 15.8 0.0 0.41 10.1 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KII94579.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 KII94579.1 - 0.023 14.2 0.8 0.058 12.9 0.6 1.7 1 1 1 2 2 2 0 Esterase PHB depolymerase Peptidase_S15 PF02129.18 KII94579.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.9 KII94579.1 - 0.057 12.5 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 BTB PF00651.31 KII94580.1 - 6e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BCS1_N PF08740.11 KII94580.1 - 0.076 13.0 1.6 0.11 12.5 0.4 1.7 1 1 0 1 1 1 0 BCS1 N terminal BTB PF00651.31 KII94582.1 - 3.6e-06 27.2 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII94583.1 - 7.3e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII94584.1 - 2.4e-06 27.7 0.1 3.8e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Tri3 PF07428.11 KII94585.1 - 3.7e-18 65.6 0.0 8.8e-17 61.1 0.0 2.0 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Peptidase_M24 PF00557.24 KII94586.1 - 2.9e-49 167.6 0.0 3.4e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CbtB PF09489.10 KII94586.1 - 0.39 10.9 1.7 0.82 9.8 1.7 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) AA_permease PF00324.21 KII94587.1 - 8.9e-114 380.7 43.7 1.1e-113 380.4 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII94587.1 - 5.2e-32 111.2 51.5 6.3e-32 110.9 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease TAF4 PF05236.14 KII94588.1 - 3.9e-38 131.8 0.8 5.9e-38 131.2 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family UPF0688 PF15772.5 KII94588.1 - 2.7 8.2 8.1 0.39 10.9 1.5 2.1 1 1 0 2 2 2 0 UPF0688 family zf-CCCH_4 PF18044.1 KII94589.1 - 2.5e-05 23.9 2.9 4.2e-05 23.2 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KII94589.1 - 7.1e-05 22.7 6.3 0.00012 22.0 6.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KII94589.1 - 0.00013 21.7 1.8 0.00021 21.1 1.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KII94589.1 - 0.21 12.3 0.6 0.41 11.4 0.6 1.5 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KII94589.1 - 0.28 11.7 4.7 0.46 11.0 4.7 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger bPH_3 PF14470.6 KII94590.1 - 0.0019 18.5 0.0 0.007 16.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 KII94590.1 - 0.0047 17.1 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KII94590.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DUF4491 PF14898.6 KII94591.1 - 0.033 14.6 4.6 0.033 14.6 4.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) EVE PF01878.18 KII94592.1 - 6.4e-42 143.0 0.3 1.2e-41 142.1 0.3 1.5 1 0 0 1 1 1 1 EVE domain RR_TM4-6 PF06459.12 KII94592.1 - 2.8 7.7 7.2 4.1 7.1 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_7 PF01145.25 KII94593.1 - 7.9e-24 84.6 5.9 1.3e-23 84.0 5.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family ZnuA PF01297.17 KII94593.1 - 0.14 11.5 0.4 0.22 10.9 0.4 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic RGS PF00615.19 KII94594.1 - 0.00061 20.1 0.0 0.0014 18.9 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Spore_YhcN_YlaJ PF09580.10 KII94595.1 - 0.43 10.7 4.3 0.74 9.9 0.1 3.0 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Bacillus_HBL PF05791.11 KII94595.1 - 0.97 9.2 9.4 0.095 12.5 1.2 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) VSG_B PF13206.6 KII94595.1 - 2.9 7.1 9.3 6.5 5.9 9.3 1.6 1 0 0 1 1 1 0 Trypanosomal VSG domain FapA PF03961.13 KII94595.1 - 3.3 6.2 11.9 0.96 8.0 8.3 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1192 PF06698.11 KII94595.1 - 3.4 7.8 9.6 13 5.9 4.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) NYD-SP28_assoc PF14775.6 KII94595.1 - 4 7.6 8.5 1.4 9.1 0.2 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain RasGAP PF00616.19 KII94596.1 - 2.9e-23 82.7 0.1 2.3e-15 56.8 0.1 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KII94596.1 - 4.5e-08 33.3 0.1 1.1e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KII94596.1 - 0.0028 17.6 0.9 0.015 15.2 0.2 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal RRM_1 PF00076.22 KII94598.1 - 6.4e-32 109.2 0.0 4.4e-16 58.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KII94598.1 - 3.3e-05 23.8 0.0 7.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 KII94598.1 - 0.0011 18.9 0.0 0.0043 17.0 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KII94598.1 - 0.023 14.8 0.0 0.81 9.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif RRM_5 PF13893.6 KII94598.1 - 0.046 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRP7 PF12923.7 KII94599.1 - 1.8e-29 102.3 4.0 1.8e-29 102.3 4.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KII94599.1 - 7.5e-12 45.3 0.0 1.8e-11 44.1 0.0 1.6 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KII94599.1 - 0.054 13.3 0.2 0.54 10.1 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEX19 PF15553.6 KII94599.1 - 0.25 11.3 1.0 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF498 PF04430.14 KII94600.1 - 6.9e-35 119.4 0.0 8.6e-35 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.13 KII94602.1 - 0.00021 21.3 14.5 0.00039 20.5 6.8 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 KII94602.1 - 0.00045 20.2 14.4 0.011 15.7 6.7 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DB PF01682.19 KII94602.1 - 0.75 10.1 8.2 49 4.3 8.3 2.1 1 1 0 1 1 1 0 DB module COX6B PF02297.17 KII94602.1 - 1.7 8.9 12.8 0.18 12.1 4.6 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KII94602.1 - 2 8.8 11.6 18 5.7 1.0 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KII94602.1 - 7.5 6.7 15.2 13 5.9 3.4 3.0 1 1 3 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_LplA_LipB PF03099.19 KII94603.1 - 2.3e-07 30.8 0.0 3.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 KII94603.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus PBP_like PF12727.7 KII94603.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PBP superfamily domain MWFE PF15879.5 KII94604.1 - 1.4e-24 86.0 0.5 1.8e-24 85.7 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit TB2_DP1_HVA22 PF03134.19 KII94606.1 - 5.8e-13 48.6 0.1 1.6e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.17 KII94607.1 - 1.1e-67 226.4 7.0 1.2e-67 226.2 7.0 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.21 KII94608.1 - 2.4e-51 174.7 52.0 3.6e-51 174.1 52.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DIOX_N PF14226.6 KII94609.1 - 1.3e-29 103.3 0.0 2.1e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII94609.1 - 2.6e-19 69.6 0.0 4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YdjO PF14169.6 KII94611.1 - 0.076 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Cold-inducible protein YdjO GDPD PF03009.17 KII94612.1 - 1.3e-31 110.2 0.0 1.8e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KII94612.1 - 1.2e-05 25.6 0.5 1.2e-05 25.6 0.5 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 KII94613.1 - 4.2e-31 107.3 0.0 5.9e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4167 PF13763.6 KII94614.1 - 0.12 12.6 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Hamartin PF04388.12 KII94614.1 - 7.2 5.1 16.5 7.9 5.0 16.5 1.0 1 0 0 1 1 1 0 Hamartin protein DASH_Spc19 PF08287.11 KII94616.1 - 2.5e-26 92.4 7.9 1.4e-25 90.0 7.9 1.9 1 1 0 1 1 1 1 Spc19 DUF1319 PF07028.11 KII94616.1 - 0.009 16.2 0.7 0.02 15.1 0.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) CASP_C PF08172.12 KII94616.1 - 0.011 15.1 2.0 0.013 14.8 2.0 1.2 1 0 0 1 1 1 0 CASP C terminal DUF4407 PF14362.6 KII94616.1 - 0.091 12.1 1.9 0.13 11.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LSDAT_euk PF18139.1 KII94616.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM FlxA PF14282.6 KII94616.1 - 0.26 11.3 5.6 5.4 7.1 0.2 2.2 2 0 0 2 2 2 0 FlxA-like protein PspB PF06667.12 KII94616.1 - 1.1 9.4 4.1 3.4 7.8 1.2 2.3 2 0 0 2 2 2 0 Phage shock protein B GIT_CC PF16559.5 KII94616.1 - 1.7 8.6 5.3 0.48 10.3 1.8 1.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor MoCF_biosynth PF00994.24 KII94617.1 - 4.6e-58 195.0 0.3 4.3e-29 101.0 0.3 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KII94617.1 - 2.8e-34 118.1 0.0 4.3e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KII94617.1 - 7.5e-15 54.9 0.5 2.2e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Nup88 PF10168.9 KII94618.1 - 5.2e-27 94.0 0.0 2.2e-13 48.9 0.0 2.8 3 1 0 3 3 3 2 Nuclear pore component Nup54 PF13874.6 KII94618.1 - 0.00079 19.6 4.4 0.00079 19.6 4.4 2.5 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 DUF1640 PF07798.11 KII94618.1 - 0.019 15.0 1.7 0.081 13.0 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4376 PF14301.6 KII94618.1 - 0.069 13.5 1.0 0.62 10.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) ANAPC4_WD40 PF12894.7 KII94618.1 - 0.15 12.3 0.0 28 5.1 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nsp1_C PF05064.13 KII94620.1 - 1.1e-32 112.2 0.0 2.3e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KII94620.1 - 6.6e-12 46.1 117.7 9.7e+02 0.7 56.8 5.7 1 1 1 2 2 2 0 Nucleoporin FG repeat region CENP-Q PF13094.6 KII94620.1 - 0.52 10.5 2.4 6.8 6.9 1.6 2.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.11 KII94620.1 - 0.95 10.1 2.5 30 5.2 2.4 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 KII94620.1 - 1.5 9.3 2.7 2.5 8.5 0.2 2.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KII94620.1 - 1.9 9.0 3.9 75 3.9 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein T2SSC PF11356.8 KII94620.1 - 8.2 6.3 9.9 1.6 8.6 1.7 3.2 1 1 0 2 2 2 0 Type II secretion system protein C Kelch_4 PF13418.6 KII94622.1 - 4.7e-19 68.1 7.9 0.0036 17.3 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KII94622.1 - 1.8e-16 60.0 15.9 0.0001 22.5 0.0 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 KII94622.1 - 5.7e-07 29.0 2.4 0.033 13.8 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 KII94622.1 - 3.7e-06 26.8 3.5 0.62 10.1 0.1 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KII94622.1 - 4e-06 26.9 8.5 1.4 9.3 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 KII94622.1 - 0.071 13.1 6.8 1.1 9.3 0.1 5.1 6 0 0 6 6 6 0 Kelch motif MARVEL PF01284.23 KII94622.1 - 0.7 9.9 11.2 0.13 12.3 4.2 2.7 2 1 0 2 2 2 0 Membrane-associating domain Borrelia_P83 PF05262.11 KII94623.1 - 1.9 6.9 5.2 2.7 6.4 5.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.10 KII94624.1 - 0.09 12.2 21.6 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SPX PF03105.19 KII94624.1 - 0.097 12.6 16.7 0.16 11.9 16.7 1.4 1 0 0 1 1 1 0 SPX domain Utp14 PF04615.13 KII94624.1 - 2 6.9 11.5 2.5 6.6 11.5 1.1 1 0 0 1 1 1 0 Utp14 protein DUF966 PF06136.13 KII94624.1 - 3.3 7.3 19.8 4.8 6.8 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 KII94624.1 - 5.9 5.6 12.6 8.8 5.0 12.6 1.3 1 0 0 1 1 1 0 Presenilin Toxin_12 PF07740.12 KII94625.1 - 0.0018 18.9 2.7 0.004 17.8 2.8 1.6 1 1 0 1 1 1 1 Ion channel inhibitory toxin Glyco_hydro2_C5 PF18565.1 KII94626.1 - 0.037 13.9 0.2 0.077 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Zn_clus PF00172.18 KII94627.1 - 9.5e-05 22.4 5.6 0.00018 21.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.22 KII94629.1 - 2.1e-99 333.8 0.0 2.6e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase TMEM208_SND2 PF05620.11 KII94630.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 GDPD PF03009.17 KII94631.1 - 1.1e-31 110.6 0.0 3.4e-31 108.9 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KII94631.1 - 2.1e-07 31.2 0.5 6.7e-07 29.6 0.5 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Nitrate_red_del PF02613.15 KII94631.1 - 0.14 12.2 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Nitrate reductase delta subunit Acetyltransf_1 PF00583.25 KII94632.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Mgm101p PF06420.12 KII94633.1 - 1.4e-86 288.3 0.0 1.8e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 GCP_N_terminal PF17681.1 KII94634.1 - 5.2e-40 138.0 0.0 8.3e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KII94634.1 - 1.3e-32 113.5 0.1 2.5e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF3246 PF11596.8 KII94634.1 - 2.5 7.5 6.4 12 5.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GatB_N PF02934.15 KII94635.1 - 3e-107 358.1 0.0 3.7e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KII94635.1 - 3.6e-31 108.1 0.0 5.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 GatB domain Thioredoxin_4 PF13462.6 KII94636.1 - 5e-08 33.3 0.0 1.3e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin PCI PF01399.27 KII94637.1 - 2.7e-14 53.6 0.0 5.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF2894 PF11445.8 KII94638.1 - 0.0015 19.1 0.0 0.0064 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2894) VWA PF00092.28 KII94638.1 - 0.0044 17.3 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain FAA_hydrolase PF01557.18 KII94639.1 - 1.9e-55 187.9 0.0 2.5e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Nop14 PF04147.12 KII94640.1 - 3.2e-295 981.9 0.6 3.8e-295 981.6 0.6 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 KII94640.1 - 0.23 10.7 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 Noc2p family eIF-3_zeta PF05091.12 KII94641.1 - 1.3e-212 707.4 0.0 1.5e-212 707.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 KII94641.1 - 0.18 11.3 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus RRM_1 PF00076.22 KII94642.1 - 2.7e-17 62.3 0.0 4.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII94642.1 - 2.3e-06 27.6 0.0 5.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KII94642.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1314 PF07013.11 KII94642.1 - 0.0097 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1314) PI3K_1B_p101 PF10486.9 KII94642.1 - 0.092 10.5 4.5 0.11 10.2 4.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GET2 PF08690.10 KII94642.1 - 0.19 11.4 5.6 0.11 12.1 3.9 1.4 1 1 0 1 1 1 0 GET complex subunit GET2 DUF1631 PF07793.11 KII94642.1 - 1.6 7.1 9.0 2 6.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DER1 PF04511.15 KII94644.1 - 5.3e-07 29.7 4.0 7.6e-07 29.3 4.0 1.3 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 KII94644.1 - 6e-06 26.3 4.6 1.1e-05 25.4 4.6 1.5 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 KII94644.1 - 0.0031 17.2 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1751 PF08551.10 KII94644.1 - 0.0051 17.3 0.2 0.0096 16.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.7 KII94649.1 - 8.5e-16 58.4 2.3 1.2e-15 57.9 2.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KII94649.1 - 0.00012 21.9 5.0 0.00019 21.3 5.0 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KII94649.1 - 0.0094 16.2 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KII94649.1 - 0.046 13.9 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain FlgN PF05130.12 KII94649.1 - 0.23 11.9 4.0 0.4 11.2 4.0 1.3 1 0 0 1 1 1 0 FlgN protein Lzipper-MIP1 PF14389.6 KII94649.1 - 0.27 11.6 4.0 5.7 7.3 0.5 2.6 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GATA PF00320.27 KII94650.1 - 2.4e-08 33.4 4.2 4.6e-08 32.5 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Dehydrin PF00257.19 KII94650.1 - 0.0094 16.5 0.2 0.019 15.5 0.2 1.6 1 0 0 1 1 1 1 Dehydrin ArfGap PF01412.18 KII94650.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf TRP PF06011.12 KII94653.1 - 1.7e-29 102.8 14.6 1.8e-28 99.5 14.6 2.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KII94653.1 - 0.06 13.7 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 ML-like domain Enkurin PF13864.6 KII94655.1 - 0.026 14.9 0.8 0.053 14.0 0.1 1.8 2 1 1 3 3 3 0 Calmodulin-binding DUF5312 PF17239.2 KII94655.1 - 0.068 11.5 0.0 0.097 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) Beta_helix PF13229.6 KII94656.1 - 2.2e-11 43.8 16.7 2.2e-11 43.8 16.7 3.2 1 1 2 3 3 3 2 Right handed beta helix region NosD PF05048.13 KII94656.1 - 0.079 12.2 18.1 2.5 7.3 17.9 2.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) MtrG PF04210.13 KII94656.1 - 0.16 11.9 0.6 0.33 10.8 0.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G PAP_central PF04928.17 KII94657.1 - 2.6e-111 370.5 0.0 4.1e-111 369.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KII94657.1 - 1e-55 188.0 0.0 1.7e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KII94657.1 - 6.6e-11 42.4 0.0 1.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KII94657.1 - 0.028 14.2 0.1 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DUF2922 PF11148.8 KII94657.1 - 0.076 12.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) LRR_2 PF07723.13 KII94659.1 - 0.94 10.3 4.2 41 5.1 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat PAPS_reduct PF01507.19 KII94660.1 - 4e-39 134.4 0.0 4.9e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonucleas_3_3 PF14622.6 KII94661.1 - 3.1e-17 62.9 0.0 4.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KII94661.1 - 5e-13 49.6 0.0 1.9e-12 47.7 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 KII94661.1 - 1.8e-06 28.5 0.0 3.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Coiled-coil_56 PF09813.9 KII94662.1 - 6.5e-06 26.1 0.0 9.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.15 KII94663.1 - 7.4e-17 61.5 0.5 8.5e-17 61.3 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII DUF2464 PF10240.9 KII94664.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 YEATS PF03366.16 KII94665.1 - 1.2e-37 127.7 0.1 1.8e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family APG6_N PF17675.1 KII94665.1 - 0.0054 17.3 0.4 0.0083 16.7 0.4 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7_N PF15402.6 KII94665.1 - 0.0073 14.6 0.3 0.0096 14.2 0.3 1.1 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 UPF0240 PF06784.11 KII94665.1 - 0.012 15.6 1.6 0.018 15.1 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) M16C_assoc PF08367.11 KII94665.1 - 0.082 12.0 4.3 0.13 11.4 4.3 1.2 1 0 0 1 1 1 0 Peptidase M16C associated PI3_PI4_kinase PF00454.27 KII94666.1 - 2.3e-52 178.3 0.0 5.8e-52 177.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KII94666.1 - 4.6e-32 111.6 0.0 9.7e-32 110.5 0.0 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KII94666.1 - 1.5e-28 98.7 0.0 5.7e-26 90.4 0.0 3.2 2 0 0 2 2 2 2 UME (NUC010) domain FATC PF02260.20 KII94666.1 - 1.3e-09 37.7 0.7 6.3e-09 35.5 0.2 2.5 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 KII94666.1 - 0.093 12.6 0.1 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Xpo1 PF08389.12 KII94666.1 - 0.34 11.0 7.9 0.22 11.6 0.4 4.2 4 1 0 4 4 4 0 Exportin 1-like protein TFIID-18kDa PF02269.16 KII94667.1 - 3e-32 110.5 0.1 6.2e-32 109.5 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KII94667.1 - 0.0069 16.7 1.8 0.015 15.6 1.8 1.6 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha Atg29_N PF18388.1 KII94668.1 - 1.5e-16 59.9 0.2 2.9e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain Lge1 PF11488.8 KII94668.1 - 0.1 12.8 0.3 0.1 12.8 0.3 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Thaumatin PF00314.17 KII94670.1 - 4.4e-66 222.6 9.8 5e-66 222.4 9.8 1.0 1 0 0 1 1 1 1 Thaumatin family PQQ PF01011.21 KII94670.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Proteasome PF00227.26 KII94671.1 - 2.9e-44 150.8 0.1 3.4e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 KII94672.1 - 3.3e-29 101.7 0.0 5.1e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KII94672.1 - 2.3e-05 24.0 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 KII94673.1 - 4.3e-49 166.6 0.0 5.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII94673.1 - 1.8e-13 49.9 0.1 3.3e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CDT1_C PF16679.5 KII94674.1 - 7.3e-12 45.6 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain CytochromB561_N PF09786.9 KII94674.1 - 0.32 9.9 12.6 0.55 9.2 12.6 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal GFO_IDH_MocA PF01408.22 KII94675.1 - 1e-16 61.8 0.2 1.6e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII94675.1 - 1.5e-06 28.2 0.0 1.5e-05 25.0 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase family, C-terminal alpha/beta domain MukB PF04310.12 KII94675.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 MukB N-terminal Mito_fiss_Elm1 PF06258.11 KII94675.1 - 0.076 12.1 0.3 0.18 10.9 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial fission ELM1 DUF1748 PF08520.10 KII94676.1 - 8.7e-25 86.4 0.0 9.6e-25 86.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) RNR_inhib PF08591.10 KII94677.1 - 2.1e-05 25.8 0.2 3.3e-05 25.1 0.2 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor zf-H2C2_2 PF13465.6 KII94678.1 - 9.8e-07 28.9 14.3 0.001 19.4 3.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KII94678.1 - 3.2e-06 27.3 1.1 3.2e-06 27.3 1.1 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII94678.1 - 0.00036 21.1 19.5 0.0026 18.4 0.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KII94678.1 - 0.00045 20.1 1.5 0.0012 18.8 1.5 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 KII94678.1 - 0.041 14.3 0.6 0.041 14.3 0.6 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII94678.1 - 0.052 13.9 0.3 0.24 11.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 KII94678.1 - 0.094 12.3 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 KII94678.1 - 0.11 12.4 1.4 2 8.4 0.6 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF4764 PF15961.5 KII94678.1 - 0.38 9.4 3.5 0.71 8.5 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Aminotran_1_2 PF00155.21 KII94679.1 - 1.3e-58 198.9 0.0 1.5e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KII94679.1 - 2.4e-05 23.8 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KII94679.1 - 0.00024 19.8 0.0 0.00045 18.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KII94679.1 - 0.0015 17.5 0.0 0.053 12.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KII94679.1 - 0.0042 16.4 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Gyro_capsid PF04162.12 KII94679.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Ferric_reduct PF01794.19 KII94680.1 - 4.2e-15 56.0 8.5 1.2e-14 54.5 8.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KII94680.1 - 5.3e-15 55.4 0.0 9.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KII94680.1 - 5.9e-15 55.7 0.0 9.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ank_2 PF12796.7 KII94681.1 - 5.1e-06 27.0 0.0 7.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII94681.1 - 6.2e-06 26.7 0.0 1.8e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII94681.1 - 4.2e-05 23.7 0.0 0.00047 20.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KII94681.1 - 0.0052 17.2 0.0 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KII94681.1 - 0.027 15.0 0.0 0.96 10.2 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DUF1843 PF08898.10 KII94681.1 - 0.046 14.2 0.0 0.42 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RNF220 PF15926.5 KII94682.1 - 0.047 13.3 0.6 5.5 6.5 0.0 2.2 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 MFS_1 PF07690.16 KII94683.1 - 4.7e-45 154.0 40.9 4.7e-45 154.0 40.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII94683.1 - 1e-05 24.6 23.8 5.4e-05 22.2 23.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KII94683.1 - 0.0022 16.5 4.9 0.0035 15.8 4.9 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.12 KII94683.1 - 0.006 15.2 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Ferroportin1 (FPN1) E1-E2_ATPase PF00122.20 KII94683.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 E1-E2 ATPase GbpC PF08363.10 KII94683.1 - 0.26 10.7 0.1 0.37 10.2 0.1 1.1 1 0 0 1 1 1 0 Glucan-binding protein C DEAD PF00270.29 KII94684.1 - 7.3e-52 175.7 0.0 6.4e-51 172.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94684.1 - 2.4e-26 92.2 0.0 7.5e-26 90.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII94684.1 - 0.00061 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KII94684.1 - 0.36 10.1 0.0 0.36 10.1 0.0 2.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PI31_Prot_N PF11566.8 KII94685.1 - 7.7e-44 149.4 0.0 9.5e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KII94685.1 - 8.7e-13 49.3 16.2 8.7e-13 49.3 16.2 2.4 3 0 0 3 3 3 1 PI31 proteasome regulator TBCC_N PF16752.5 KII94686.1 - 0.041 14.3 0.1 0.1 13.1 0.1 1.6 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain RPN2_C PF18004.1 KII94686.1 - 0.16 11.9 0.8 0.28 11.1 0.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 KII94686.1 - 7.3 5.8 7.3 9.7 5.4 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein RhgB_N PF09284.10 KII94687.1 - 2.9e-98 328.4 1.9 4.2e-98 327.9 1.9 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KII94687.1 - 2.9e-43 147.6 0.0 6.6e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KII94687.1 - 1e-15 57.2 2.4 1e-15 57.2 2.4 2.4 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KII94687.1 - 0.0048 17.2 3.1 0.0048 17.2 3.1 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Ribosomal_L13 PF00572.18 KII94688.1 - 8e-50 168.3 0.0 9.5e-50 168.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Nup188 PF10487.9 KII94690.1 - 7.7e-48 163.1 0.0 1.8e-45 155.3 0.0 3.5 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KII94690.1 - 3.6e-09 35.9 0.1 8e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain XPC-binding PF09280.11 KII94690.1 - 0.019 14.7 1.0 0.52 10.1 0.1 3.2 3 0 0 3 3 3 0 XPC-binding domain Pkinase PF00069.25 KII94691.1 - 1.4e-39 136.1 0.0 7.7e-23 81.2 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KII94691.1 - 4e-11 42.7 0.0 8.7e-09 35.0 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KII94691.1 - 8e-05 22.7 1.1 0.0027 17.7 0.0 3.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family FTA2 PF13095.6 KII94691.1 - 0.013 15.2 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1631 PF07793.11 KII94691.1 - 0.57 8.5 8.2 1.3 7.3 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) BLOC1_2 PF10046.9 KII94691.1 - 1.5 9.2 3.4 4.8 7.6 3.4 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1992 PF09350.10 KII94693.1 - 3.2e-21 75.3 0.1 7.8e-21 74.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) SbcD_C PF12320.8 KII94693.1 - 0.013 15.8 0.3 0.052 13.8 0.0 2.1 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain UCH PF00443.29 KII94694.1 - 2e-29 102.9 0.0 3.2e-29 102.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII94694.1 - 1.3e-05 25.0 0.0 5.7e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_61 PF03443.14 KII94695.1 - 5.6e-64 215.9 0.1 6.4e-64 215.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pro_isomerase PF00160.21 KII94697.1 - 9.8e-38 129.9 0.0 1.6e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KII94697.1 - 1.5e-15 56.8 0.0 4.6e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 KII94698.1 - 7.1e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Aldedh PF00171.22 KII94699.1 - 1.2e-108 363.6 0.0 1.5e-108 363.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 KII94700.1 - 3.2e-66 223.5 0.0 4e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KII94701.1 - 4.8e-46 157.3 0.0 8.4e-45 153.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Homeodomain PF00046.29 KII94701.1 - 0.008 16.0 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Homeodomain PAF-AH_p_II PF03403.13 KII94702.1 - 1.1e-52 178.9 0.0 1.4e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KII94702.1 - 3.6e-06 26.1 0.0 2.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KII94702.1 - 6.9e-06 25.5 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII94702.1 - 8.9e-06 26.5 3.4 8.9e-06 26.5 3.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KII94702.1 - 0.00022 20.3 0.0 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase WD40 PF00400.32 KII94704.1 - 7.4e-32 108.9 7.2 8.7e-05 23.2 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94704.1 - 1.1e-13 51.2 0.0 0.00014 22.1 0.0 5.0 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KII94704.1 - 0.0086 14.4 0.0 0.065 11.5 0.0 2.0 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 KII94704.1 - 0.01 15.2 0.0 0.73 9.1 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KII94704.1 - 0.031 13.2 0.0 6.7 5.6 0.0 2.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KII94704.1 - 0.04 12.8 0.1 4.4 6.1 0.1 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Lactonase PF10282.9 KII94704.1 - 0.046 13.0 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.6 KII94704.1 - 0.068 12.7 0.3 5.6 6.5 0.1 2.7 2 1 1 3 3 3 0 PQQ-like domain PQQ_3 PF13570.6 KII94704.1 - 0.86 10.2 6.0 19 5.9 0.0 4.3 4 1 0 4 4 4 0 PQQ-like domain peroxidase PF00141.23 KII94705.1 - 1.7e-27 96.7 0.0 2.3e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 KII94705.1 - 2.8e-26 91.3 0.3 5.7e-26 90.3 0.3 1.5 1 0 0 1 1 1 1 Fungal peroxidase extension region Arb1 PF09692.10 KII94706.1 - 0.0086 15.3 0.0 0.027 13.6 0.0 1.8 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Fungal_trans PF04082.18 KII94707.1 - 9.7e-22 77.3 0.0 2.1e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII94707.1 - 0.0013 18.8 8.6 0.0013 18.8 8.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KII94708.1 - 1.1e-81 275.1 25.0 1.2e-81 274.9 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII94708.1 - 1e-27 97.0 29.6 1e-27 97.0 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII94708.1 - 1.9e-08 33.2 4.3 3.8e-08 32.2 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KII94708.1 - 0.0074 15.6 7.2 0.0074 15.6 7.2 2.6 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KII94708.1 - 2.6 6.2 13.3 0.97 7.6 2.0 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ubiquitin PF00240.23 KII94709.1 - 1.7e-24 85.3 0.1 1.9e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KII94709.1 - 1.8e-12 46.9 0.3 2e-12 46.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KII94709.1 - 0.00016 21.6 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 KII94709.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KII94709.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain 2OG-FeII_Oxy_2 PF13532.6 KII94710.1 - 6.3e-14 52.6 0.0 8.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.22 KII94711.1 - 4.3e-07 30.2 0.5 1.1e-06 28.9 0.5 1.7 1 1 0 1 1 1 1 Thioesterase superfamily Transp_cyt_pur PF02133.15 KII94712.1 - 1.9e-30 106.0 36.9 7.2e-30 104.1 36.9 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 KII94713.1 - 1.5e-35 122.8 34.2 1.5e-35 122.8 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_I PF03899.15 KII94713.1 - 0.0087 16.4 1.0 0.0087 16.4 1.0 3.8 2 1 1 3 3 3 1 ATP synthase I chain 4HBT PF03061.22 KII94715.1 - 1.9e-07 31.3 0.1 2.9e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily adh_short_C2 PF13561.6 KII94716.1 - 2.8e-59 200.5 0.5 3.7e-59 200.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII94716.1 - 2.6e-50 170.6 0.1 3.5e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII94716.1 - 1.1e-17 64.5 0.1 1.7e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII94716.1 - 8.9e-05 22.1 0.1 0.00023 20.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 KII94716.1 - 0.077 14.0 0.8 0.28 12.2 0.8 2.0 1 1 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator SH3_9 PF14604.6 KII94717.1 - 1.4e-14 53.7 0.1 3.1e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 KII94717.1 - 8.6e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KII94717.1 - 2.3e-13 50.3 0.2 5.9e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.29 KII94717.1 - 3.3e-13 50.1 0.3 7.2e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 KII94717.1 - 5.8e-13 48.2 0.2 1.3e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII94717.1 - 1.9e-07 30.7 0.0 3.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CH PF00307.31 KII94717.1 - 0.00091 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain SAM_3 PF18016.1 KII94717.1 - 0.037 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KII94717.1 - 0.097 12.9 0.3 0.26 11.6 0.3 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PGA2 PF07543.12 KII94717.1 - 2.4 8.1 9.9 0.55 10.2 5.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Cytochrom_B558a PF05038.13 KII94717.1 - 2.6 7.6 7.5 0.54 9.8 0.6 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Ham1p_like PF01725.16 KII94718.1 - 1.1e-58 198.3 0.0 1.2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family TPR_1 PF00515.28 KII94719.1 - 1.9e-09 37.0 0.1 0.028 14.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII94719.1 - 2.9e-08 33.2 8.8 0.0022 18.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KII94719.1 - 1.5e-07 31.6 3.0 0.00035 20.8 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII94719.1 - 6.7e-06 25.9 0.0 1.8 9.0 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII94719.1 - 9.2e-06 26.1 11.4 0.014 16.2 0.0 6.2 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KII94719.1 - 2.2e-05 24.5 0.0 0.28 11.7 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII94719.1 - 0.00021 20.9 0.0 0.76 9.5 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 KII94719.1 - 0.00041 20.8 0.3 14 6.3 0.0 5.3 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII94719.1 - 0.00042 20.9 3.4 0.0014 19.2 0.1 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KII94719.1 - 0.0027 17.8 0.0 0.021 14.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KII94719.1 - 0.0065 16.4 8.0 3.3 8.0 0.0 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII94719.1 - 0.025 14.4 10.9 0.091 12.7 0.0 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat Acetate_kinase PF00871.17 KII94719.1 - 0.054 12.2 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Acetokinase family ANAPC3 PF12895.7 KII94719.1 - 0.077 13.2 2.3 2.1 8.6 0.0 3.9 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Rab5ip PF07019.12 KII94721.1 - 3e-20 72.6 4.4 3.8e-20 72.3 4.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Semialdhyde_dhC PF02774.18 KII94722.1 - 9e-37 126.9 0.0 1.4e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KII94722.1 - 4.4e-28 98.2 0.0 7.7e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain LRR_4 PF12799.7 KII94723.1 - 0.088 13.3 0.2 39 4.8 0.0 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII94724.1 - 3.4e-06 26.8 3.4 5.6e-06 26.2 3.4 1.4 1 1 0 1 1 1 1 F-box-like DUF1768 PF08719.11 KII94725.1 - 8.8e-18 65.1 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_3 PF08777.11 KII94726.1 - 1.6e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Ribosomal_L4 PF00573.22 KII94726.1 - 0.088 12.5 0.0 1.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein L4/L1 family SAP18 PF06487.12 KII94727.1 - 7.5e-34 116.9 0.0 1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.11 KII94727.1 - 0.17 11.2 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 F-box-like PF12937.7 KII94728.1 - 0.00011 22.0 1.8 0.00011 22.0 1.8 2.1 2 0 0 2 2 2 1 F-box-like DUF5606 PF18347.1 KII94728.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5606) Cu_amine_oxid PF01179.20 KII94729.1 - 7e-123 410.6 0.0 9.9e-123 410.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 KII94729.1 - 1.6e-07 31.0 0.0 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 KII94729.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain ATG22 PF11700.8 KII94730.1 - 7.3e-111 371.1 17.2 8.4e-111 370.9 17.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KII94730.1 - 2.1e-14 53.2 26.5 5.3e-10 38.8 6.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily TFIIF_alpha PF05793.12 KII94731.1 - 0.55 8.8 4.1 0.8 8.2 4.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribonuclease_3 PF00636.26 KII94732.1 - 1e-44 151.5 0.0 1.7e-21 76.8 0.0 3.2 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KII94732.1 - 7.4e-25 87.6 0.8 1.6e-12 47.7 0.1 4.3 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KII94732.1 - 2e-11 43.9 0.0 5.9e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KII94732.1 - 2.2e-06 28.0 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 KII94732.1 - 1.2e-05 25.2 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 KII94733.1 - 2.2e-14 53.5 0.5 2.4e-14 53.3 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.22 KII94734.1 - 5.1e-175 582.4 0.2 5.7e-175 582.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5063 PF16702.5 KII94734.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) Zn_clus PF00172.18 KII94735.1 - 4.9e-06 26.6 8.1 7.6e-06 26.0 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KII94736.1 - 2.6e-60 203.2 0.0 3.9e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII94736.1 - 2e-08 33.7 0.0 7.5e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.21 KII94737.1 - 4.3e-32 110.6 0.0 5.6e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KII94737.1 - 1.8e-14 53.7 0.0 2.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KII94737.1 - 2.9e-10 39.8 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 KII94737.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ssu72 PF04722.13 KII94738.1 - 9e-86 286.3 0.0 1.2e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.7 KII94739.1 - 3.8e-08 33.1 0.4 1.4e-07 31.3 0.4 2.1 1 0 0 1 1 1 1 F-box-like DUF16 PF01519.16 KII94739.1 - 0.096 13.2 0.2 0.17 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 EzrA PF06160.12 KII94739.1 - 0.13 10.4 0.2 0.18 9.9 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA F-box PF00646.33 KII94739.1 - 0.19 11.6 4.2 0.25 11.3 0.6 2.8 2 1 0 2 2 2 0 F-box domain Syntaxin-18_N PF10496.9 KII94740.1 - 1.1e-17 64.0 1.1 4.1e-17 62.2 0.1 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KII94740.1 - 0.0022 18.0 1.8 0.0055 16.7 0.0 2.5 3 0 0 3 3 3 1 SNARE domain ThrE PF06738.12 KII94740.1 - 0.25 10.7 0.3 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 Putative threonine/serine exporter SNARE_assoc PF09335.11 KII94741.1 - 4.5e-13 49.7 5.3 4.5e-13 49.7 5.3 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein E1-E2_ATPase PF00122.20 KII94741.1 - 0.43 10.1 1.4 0.78 9.2 0.9 1.6 2 0 0 2 2 2 0 E1-E2 ATPase DUF2207 PF09972.9 KII94741.1 - 5.5 5.6 8.8 7 5.3 5.7 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) 2OG-FeII_Oxy_3 PF13640.6 KII94742.1 - 2.5e-05 25.1 0.0 5.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.20 KII94743.1 - 6.1e-55 186.3 0.0 1.3e-54 185.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 KII94744.1 - 2.8e-19 68.7 0.0 4.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94744.1 - 4e-05 23.2 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KII94744.1 - 0.00046 20.1 0.1 0.0061 16.5 0.0 2.5 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KII94744.1 - 0.029 14.4 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif PLD_C PF12357.8 KII94744.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Phospholipase D C terminal 2OG-FeII_Oxy_3 PF13640.6 KII94746.1 - 3.8e-06 27.7 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TFIIB PF00382.19 KII94747.1 - 4.1e-36 122.8 0.9 1.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KII94747.1 - 6.4e-14 52.1 5.8 1.5e-10 41.3 0.3 2.4 2 0 0 2 2 2 2 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KII94747.1 - 5.6e-05 22.9 1.1 0.17 11.6 0.4 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Pup PF05639.11 KII94747.1 - 0.11 13.4 2.1 0.33 11.9 2.1 1.8 1 0 0 1 1 1 0 Pup-like protein TF_Zn_Ribbon PF08271.12 KII94747.1 - 0.13 11.8 0.3 0.26 10.8 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Thioredoxin_16 PF18569.1 KII94749.1 - 0.076 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Fungal_trans PF04082.18 KII94752.1 - 7.1e-18 64.6 0.1 1.6e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII94752.1 - 1.9e-05 24.7 11.9 1.9e-05 24.7 11.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MHB PF16525.5 KII94752.1 - 0.12 12.6 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Haemophore, haem-binding 2OG-FeII_Oxy_3 PF13640.6 KII94753.1 - 1e-06 29.5 0.0 2.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 KII94754.1 - 1.4e-16 60.4 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 KII94754.1 - 0.00038 20.6 3.6 0.00087 19.5 3.6 1.6 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain UBA PF00627.31 KII94754.1 - 0.01 15.7 1.1 0.035 14.0 1.1 2.0 1 0 0 1 1 1 0 UBA/TS-N domain Exonuc_VII_S PF02609.16 KII94754.1 - 0.11 12.5 0.4 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit Mito_carr PF00153.27 KII94755.1 - 2.8e-50 168.2 4.9 1.1e-16 60.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KII94755.1 - 0.0091 16.1 0.2 3 8.1 0.2 2.5 2 0 0 2 2 2 2 PrcB C-terminal p450 PF00067.22 KII94756.1 - 8.1e-73 245.7 0.0 1e-72 245.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KII94757.1 - 1.5e-75 254.8 0.0 1.8e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2929 PF11151.8 KII94757.1 - 0.084 13.2 0.3 0.23 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) RTP1_C1 PF10363.9 KII94758.1 - 2.4e-34 117.9 0.2 1e-32 112.6 0.0 3.6 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KII94758.1 - 0.0012 18.5 0.8 0.0045 16.7 0.8 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 UME PF08064.13 KII94758.1 - 0.087 12.7 0.1 16 5.5 0.0 3.4 4 0 0 4 4 4 0 UME (NUC010) domain BLM10_mid PF16507.5 KII94758.1 - 0.19 10.3 0.2 14 4.2 0.0 3.0 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region Sedlin_N PF04628.13 KII94759.1 - 1.2e-21 77.2 0.3 1.7e-21 76.7 0.3 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Opy2 PF09463.10 KII94760.1 - 0.00011 22.4 19.8 0.00019 21.6 19.8 1.4 1 0 0 1 1 1 1 Opy2 protein Phage_holin_2_4 PF16082.5 KII94760.1 - 0.26 11.1 0.7 0.67 9.7 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like ABC_tran PF00005.27 KII94761.1 - 4e-15 56.6 0.0 2.5e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII94761.1 - 4.1e-07 30.1 0.8 4.4e-05 23.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KII94761.1 - 0.00025 20.7 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KII94761.1 - 0.00048 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KII94761.1 - 0.001 19.6 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KII94761.1 - 0.004 17.1 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 KII94761.1 - 0.0041 17.2 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KII94761.1 - 0.0079 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KII94761.1 - 0.015 14.6 0.0 0.071 12.5 0.0 2.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_27 PF13514.6 KII94761.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KII94761.1 - 0.04 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.6 KII94761.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KII94761.1 - 0.054 13.4 0.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KII94761.1 - 0.08 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.9 KII94761.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 KII94761.1 - 0.14 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class CobA_CobO_BtuR PF02572.15 KII94761.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_33 PF13671.6 KII94761.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KII94761.1 - 0.16 11.6 0.4 0.59 9.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KII94761.1 - 0.2 11.7 0.1 0.3 11.1 0.1 1.2 1 0 0 1 1 1 0 Dynamin family SRP54 PF00448.22 KII94761.1 - 0.2 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KII94761.1 - 0.23 11.8 0.5 0.85 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-CCHC PF00098.23 KII94762.1 - 0.013 15.6 33.8 0.024 14.7 2.8 4.7 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 KII94762.1 - 0.021 14.8 20.8 0.95 9.5 3.7 4.6 4 0 0 4 4 4 0 Zinc knuckle UQ_con PF00179.26 KII94764.1 - 5.8e-15 55.2 0.1 7.5e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KII94764.1 - 0.027 14.8 0.0 0.045 14.0 0.0 1.6 2 0 0 2 2 2 0 RWD domain BRE PF06113.12 KII94764.1 - 0.14 11.0 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) His_Phos_2 PF00328.22 KII94765.1 - 1.4e-89 301.1 0.0 1.8e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KII94765.1 - 4.5e-38 129.3 0.0 1.2e-37 127.9 0.0 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KII94765.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.20 KII94766.1 - 6e-46 156.2 2.1 9.4e-46 155.6 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KII94766.1 - 9.1e-35 120.8 0.2 1.9e-34 119.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KII94766.1 - 1e-28 99.5 5.4 7.2e-12 45.6 1.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 KII94766.1 - 0.0017 18.8 0.0 0.0044 17.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KII94766.1 - 0.0031 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Spore_YhcN_YlaJ PF09580.10 KII94766.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) GCP_N_terminal PF17681.1 KII94767.1 - 2.1e-97 326.4 0.0 4.6e-97 325.3 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KII94767.1 - 1.1e-91 307.6 0.9 1.6e-91 307.0 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal AMP-binding PF00501.28 KII94769.1 - 3e-89 299.5 0.0 3.7e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII94769.1 - 4.3e-10 40.4 0.0 1e-09 39.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.15 KII94770.1 - 1.4e-44 151.6 0.2 4.1e-44 150.0 0.2 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.19 KII94770.1 - 2.7e-39 135.0 0.0 4.5e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 KII94770.1 - 7.1e-25 84.4 66.3 0.015 15.1 1.0 13.8 13 0 0 13 13 13 12 IQ calmodulin-binding motif CH PF00307.31 KII94770.1 - 8.6e-13 48.4 0.0 4.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.11 KII94770.1 - 0.41 10.6 1.9 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 Siphovirus Gp157 MFS_1 PF07690.16 KII94771.1 - 1.1e-37 129.9 21.5 1.7e-37 129.2 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HSP90 PF00183.18 KII94772.1 - 3.1e-133 445.4 3.0 3.1e-133 445.4 3.0 2.7 3 1 0 3 3 3 1 Hsp90 protein FF PF01846.19 KII94772.1 - 1e-35 121.7 25.2 4.2e-11 42.9 0.2 6.8 7 0 0 7 7 7 5 FF domain WW PF00397.26 KII94772.1 - 1.5e-10 41.0 5.0 3.7e-07 30.1 0.3 2.8 2 0 0 2 2 2 2 WW domain HATPase_c_3 PF13589.6 KII94772.1 - 1.3e-09 38.0 0.1 1.5e-08 34.6 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RhoGAP-FF1 PF16512.5 KII94772.1 - 3.6e-08 34.0 2.8 0.077 13.7 0.0 4.2 2 1 1 3 3 3 3 p190-A and -B Rho GAPs FF domain HATPase_c PF02518.26 KII94772.1 - 1.6e-06 28.6 0.0 3.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Git3 PF11710.8 KII94773.1 - 0.0053 16.6 10.6 0.012 15.4 10.6 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KII94773.1 - 0.014 15.5 2.4 0.019 15.0 0.0 2.4 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 KII94773.1 - 0.029 13.5 6.8 0.044 12.9 6.8 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Adipogenin PF15202.6 KII94773.1 - 0.058 13.4 1.7 0.45 10.6 0.9 2.6 2 0 0 2 2 2 0 Adipogenin MadM PF03818.13 KII94773.1 - 0.13 12.1 1.8 0.4 10.6 0.8 2.2 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit Ndc1_Nup PF09531.10 KII94773.1 - 1.6 7.3 5.2 2.5 6.7 5.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Git3 PF11710.8 KII94774.1 - 1.4e-05 24.9 11.3 3.2e-05 23.8 11.3 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KII94774.1 - 0.051 13.7 1.6 0.091 12.8 0.0 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term MOSP_N PF02707.16 KII94774.1 - 0.058 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region Adipogenin PF15202.6 KII94774.1 - 0.084 12.9 1.3 0.38 10.8 1.3 2.1 1 0 0 1 1 1 0 Adipogenin TFA2_Winged_2 PF18121.1 KII94775.1 - 6.6e-22 77.0 0.0 1.3e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KII94775.1 - 1.8e-16 60.2 0.6 8e-16 58.1 0.3 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain RNase_PH PF01138.21 KII94776.1 - 1.7e-25 90.1 0.0 2.4e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KII94776.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SMC_N PF02463.19 KII94777.1 - 1.5e-20 73.6 0.1 2.7e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KII94777.1 - 1.6e-09 38.6 24.8 1.6e-09 38.6 24.8 5.8 3 2 0 4 4 4 1 AAA domain AAA_15 PF13175.6 KII94777.1 - 5e-05 23.2 4.1 5e-05 23.2 4.1 3.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_29 PF13555.6 KII94777.1 - 0.0092 15.7 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KII94777.1 - 0.017 14.9 0.2 0.017 14.9 0.2 4.0 4 1 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system TcpS PF17456.2 KII94777.1 - 0.027 14.5 0.4 0.027 14.5 0.4 3.8 3 0 0 3 3 3 0 Toxin-coregulated pilus protein S IstB_IS21 PF01695.17 KII94777.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PhageMin_Tail PF10145.9 KII94777.1 - 0.29 11.0 3.9 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Phage-related minor tail protein AAA_27 PF13514.6 KII94777.1 - 0.59 9.7 0.0 0.59 9.7 0.0 4.1 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KII94777.1 - 6.2 7.3 16.5 5.6 7.5 6.0 4.2 3 1 0 3 3 3 0 ABC transporter Calcipressin PF04847.12 KII94778.1 - 0.73 9.5 6.1 1.3 8.7 6.1 1.3 1 0 0 1 1 1 0 Calcipressin Auto_anti-p27 PF06677.12 KII94782.1 - 1.6e-27 95.3 4.4 6e-14 51.9 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.21 KII94782.1 - 0.052 13.8 1.4 0.55 10.5 0.1 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Glyco_hydro_47 PF01532.20 KII94783.1 - 7.9e-111 371.2 0.0 1.2e-110 370.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KII94783.1 - 8.8e-07 28.9 0.1 2.2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Pribosyltran PF00156.27 KII94784.1 - 3.1e-14 52.8 0.1 4.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KII94784.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_S3Ae PF01015.18 KII94785.1 - 1.1e-95 319.0 1.9 1.3e-95 318.8 1.9 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KII94785.1 - 0.025 14.1 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SUI1 PF01253.22 KII94785.1 - 0.073 13.6 0.1 3.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor SUI1 TipAS PF07739.13 KII94785.1 - 0.097 13.2 0.1 0.76 10.3 0.0 2.3 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain Autophagy_act_C PF03987.15 KII94786.1 - 1.4e-17 64.0 0.1 2.4e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Thiolase_N PF00108.23 KII94787.1 - 8.3e-86 287.6 2.1 1.1e-85 287.2 2.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KII94787.1 - 2.8e-38 130.3 0.9 2.8e-38 130.3 0.9 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KII94787.1 - 5.9e-05 22.8 2.3 0.0013 18.4 1.0 2.5 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KII94787.1 - 0.022 14.6 0.7 0.5 10.3 0.3 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.16 KII94788.1 - 1.3e-32 113.1 24.8 1.8e-32 112.7 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII94788.1 - 2e-05 24.1 14.3 3.2e-05 23.4 4.8 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF4181 PF13789.6 KII94788.1 - 0.0032 17.7 1.7 2.8 8.2 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4181) Phage_holin_5_1 PF06946.11 KII94788.1 - 0.45 10.9 3.3 0.37 11.2 0.8 2.2 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 MFS_1 PF07690.16 KII94789.1 - 3.6e-31 108.4 21.7 5.1e-31 107.9 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KII94789.1 - 0.02 15.3 0.2 0.043 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF4381 PF14316.6 KII94789.1 - 0.064 13.5 0.2 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) OSTbeta PF15048.6 KII94789.1 - 0.065 13.4 0.2 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Saf_2TM PF18303.1 KII94789.1 - 0.12 11.9 0.4 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain ACPS PF01648.20 KII94790.1 - 2e-15 56.9 0.0 2.3e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GCV_T PF01571.21 KII94791.1 - 1.6e-05 24.4 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Pet191_N PF10203.9 KII94792.1 - 8.4e-26 90.1 5.8 9.8e-26 89.8 5.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 KII94792.1 - 1.4 9.1 5.1 13 6.1 1.3 2.4 2 0 0 2 2 2 0 CHCH domain Piwi PF02171.17 KII94793.1 - 2.1e-75 253.8 0.0 3.4e-75 253.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 KII94793.1 - 3.1e-13 49.2 0.0 7.7e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KII94793.1 - 3.9e-08 33.4 0.0 1.1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 KII94793.1 - 1.4e-05 25.7 0.0 0.00015 22.4 0.0 2.5 1 1 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KII94793.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KII94793.1 - 0.0017 18.7 0.0 0.006 16.9 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain Gp5_C PF06715.12 KII94795.1 - 0.019 15.0 2.4 0.019 15.0 2.4 4.6 5 0 0 5 5 5 0 Gp5 C-terminal repeat (3 copies) DUF1640 PF07798.11 KII94796.1 - 1.9e-34 119.2 7.1 2.2e-34 119.0 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Med11 PF10280.9 KII94796.1 - 0.037 14.5 0.1 0.048 14.1 0.1 1.3 1 0 0 1 1 1 0 Mediator complex protein cEGF PF12662.7 KII94797.1 - 0.017 15.1 3.9 0.02 14.8 1.4 2.4 2 0 0 2 2 2 0 Complement Clr-like EGF-like Dynamin_N PF00350.23 KII94798.1 - 6.2e-18 65.4 0.0 6.2e-18 65.4 0.0 3.5 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KII94798.1 - 2.5e-06 27.5 0.0 0.0045 17.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Apolipoprotein PF01442.18 KII94798.1 - 0.00019 21.4 3.9 0.00019 21.4 3.9 4.8 5 1 0 5 5 5 2 Apolipoprotein A1/A4/E domain ABC_tran PF00005.27 KII94798.1 - 0.0007 20.1 0.9 0.0058 17.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 KII94798.1 - 0.0013 18.7 0.1 0.005 16.8 0.1 2.0 1 0 0 1 1 1 1 RsgA GTPase Flagellar_rod PF05149.12 KII94798.1 - 0.0022 17.5 0.3 0.0022 17.5 0.3 2.8 3 0 0 3 3 2 1 Paraflagellar rod protein FtsK_SpoIIIE PF01580.18 KII94798.1 - 0.017 14.5 0.0 0.017 14.5 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KII94798.1 - 0.019 15.3 2.9 0.14 12.6 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KII94798.1 - 0.019 15.2 0.1 0.18 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF842 PF05811.13 KII94798.1 - 0.038 13.7 0.9 0.13 12.0 0.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AAA_23 PF13476.6 KII94798.1 - 0.048 14.2 0.1 0.048 14.2 0.1 4.4 4 1 0 4 4 3 0 AAA domain ChaB PF06150.12 KII94798.1 - 0.048 14.2 0.5 1.2 9.8 0.0 3.5 3 0 0 3 3 3 0 ChaB T2SSE PF00437.20 KII94798.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KII94798.1 - 0.13 12.0 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mlh1_C PF16413.5 KII94798.1 - 0.14 11.5 1.9 5.4 6.3 0.9 2.7 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus EzrA PF06160.12 KII94798.1 - 0.48 8.5 10.9 2.1 6.4 0.9 2.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF87 PF01935.17 KII94798.1 - 2.5 8.1 6.0 2.2 8.3 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain B3 PF02362.21 KII94799.1 - 0.23 11.4 2.4 0.59 10.0 2.4 1.8 1 1 0 1 1 1 0 B3 DNA binding domain ATP_bind_1 PF03029.17 KII94800.1 - 1.2e-72 244.6 0.0 5e-72 242.6 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KII94800.1 - 0.0001 22.7 0.0 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KII94800.1 - 0.00048 19.3 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 KII94800.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_29 PF13555.6 KII94800.1 - 0.0043 16.8 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KII94800.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KII94800.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MeaB PF03308.16 KII94800.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KII94800.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF463 PF04317.12 KII94800.1 - 0.019 13.9 0.0 0.051 12.5 0.0 1.6 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_24 PF13479.6 KII94800.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KII94800.1 - 0.028 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KII94800.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase PF06745.13 KII94800.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KII94800.1 - 0.034 14.1 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KII94800.1 - 0.037 14.6 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KII94800.1 - 0.044 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KII94800.1 - 0.045 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KII94800.1 - 0.049 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KII94800.1 - 0.051 12.8 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KII94800.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 KII94800.1 - 0.083 13.4 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KII94800.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 KII94800.1 - 0.11 12.1 0.0 0.54 9.8 0.0 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KII94800.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KII94800.1 - 0.14 12.2 0.0 1.3 9.2 0.0 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.16 KII94800.1 - 0.15 11.5 0.0 0.9 9.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Ploopntkinase3 PF18751.1 KII94800.1 - 0.15 11.9 0.0 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CLP1_P PF16575.5 KII94800.1 - 0.15 11.8 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CobU PF02283.16 KII94800.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KTI12 PF08433.10 KII94800.1 - 0.24 10.8 0.0 0.4 10.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mago-bind PF09282.10 KII94801.1 - 1.9e-14 53.2 1.5 4e-14 52.2 1.5 1.5 1 0 0 1 1 1 1 Mago binding SOG2 PF10428.9 KII94801.1 - 1.1 8.3 4.7 1.2 8.2 4.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3824 PF12868.7 KII94801.1 - 2 9.0 15.6 0.34 11.6 11.8 1.6 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) WD40 PF00400.32 KII94803.1 - 1.3e-39 133.4 24.0 2.9e-05 24.7 0.1 10.8 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94803.1 - 4.8e-08 33.2 1.9 0.92 9.8 0.6 6.8 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII94803.1 - 0.00029 19.9 0.1 4.4 6.2 0.0 4.4 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 KII94803.1 - 0.00091 19.2 0.0 0.14 12.2 0.0 3.5 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DEAD PF00270.29 KII94804.1 - 1e-18 67.7 0.0 2.3e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94804.1 - 2.9e-08 34.0 0.0 9.7e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 KII94805.1 - 8.6e-12 44.7 0.0 5.5e-08 32.5 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII94805.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif UPF0020 PF01170.18 KII94805.1 - 0.044 13.5 0.0 0.41 10.3 0.0 2.1 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 DUF4100 PF13352.6 KII94805.1 - 0.13 12.0 2.7 0.18 11.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) DUF2561 PF10812.8 KII94805.1 - 0.16 12.0 0.2 0.31 11.0 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) Complex1_LYR_2 PF13233.6 KII94806.1 - 4.4e-14 53.0 0.1 6.2e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HMG_box PF00505.19 KII94807.1 - 2.5e-12 47.0 0.9 5.7e-12 45.9 0.9 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII94807.1 - 3.4e-05 24.3 0.6 8.8e-05 23.0 0.6 1.7 1 1 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KII94807.1 - 0.18 11.1 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Sua5_yciO_yrdC PF01300.18 KII94808.1 - 2.3e-51 173.8 0.0 4.1e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KII94808.1 - 1.4e-30 106.6 0.0 2.1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.29 KII94809.1 - 1.7e-43 148.4 0.0 3.1e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94809.1 - 3.4e-25 88.5 0.0 1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mob1_phocein PF03637.17 KII94811.1 - 9e-79 263.4 0.0 1.1e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.24 KII94812.1 - 9.4e-17 61.3 0.0 1.8e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KII94812.1 - 2.4e-08 33.9 0.0 1.5e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KII94813.1 - 5.3e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KII94813.1 - 9.8e-08 31.9 0.0 1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KII94814.1 - 6e-15 55.4 0.0 1.2e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KII94814.1 - 1e-07 31.9 0.1 1.2e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like TPR_3 PF07720.12 KII94814.1 - 0.042 13.8 0.8 0.37 10.8 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat BRCT PF00533.26 KII94814.1 - 0.092 13.1 0.0 0.34 11.3 0.0 2.0 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 KII94815.1 - 2.4e-19 68.9 0.2 8.3e-10 38.4 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94815.1 - 0.00071 19.2 0.0 0.0086 15.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII94815.1 - 0.0026 17.6 0.0 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DNA_pol_phi PF04931.13 KII94815.1 - 1.2 7.1 5.0 1.7 6.7 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAM_LAG1_CLN8 PF03798.16 KII94816.1 - 7.4e-38 130.3 25.3 1.1e-37 129.7 25.3 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KII94816.1 - 2e-10 40.2 0.1 2e-10 40.2 0.1 2.7 2 0 0 2 2 2 1 TRAM1-like protein Peptidase_A22B PF04258.13 KII94816.1 - 4.4 6.7 16.9 0.94 8.9 13.6 1.5 2 0 0 2 2 2 0 Signal peptide peptidase Snf7 PF03357.21 KII94817.1 - 1.2e-31 109.6 19.5 1.5e-31 109.3 19.5 1.2 1 0 0 1 1 1 1 Snf7 NIF PF03031.18 KII94818.1 - 6.2e-52 175.5 0.0 8.4e-52 175.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FMN_dh PF01070.18 KII94819.1 - 3.3e-118 394.7 0.0 4.3e-118 394.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KII94819.1 - 4.3e-17 62.0 0.0 8.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KII94819.1 - 4.6e-05 22.6 0.3 0.0063 15.6 0.2 3.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KII94819.1 - 0.00032 19.9 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KII94819.1 - 0.0057 16.1 0.4 0.029 13.8 0.7 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase Peptidase_M19 PF01244.21 KII94819.1 - 0.043 13.0 0.0 0.09 11.9 0.0 1.5 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) His_biosynth PF00977.21 KII94819.1 - 0.099 12.1 0.1 19 4.6 0.1 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein MFS_1 PF07690.16 KII94820.1 - 5.8e-35 120.9 31.5 5.8e-35 120.9 31.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-rbx1 PF12678.7 KII94821.1 - 6.3e-06 26.4 0.5 1.1e-05 25.7 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KII94821.1 - 3.2e-05 23.7 0.3 5.5e-05 23.0 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII94821.1 - 8.2e-05 22.4 0.2 8.2e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KII94821.1 - 0.00012 22.3 5.2 0.0015 18.8 5.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KII94821.1 - 0.00069 19.4 0.9 0.0057 16.4 0.4 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KII94821.1 - 0.00074 19.5 0.0 0.0035 17.3 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII94821.1 - 0.0013 18.5 2.9 0.0036 17.1 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII94821.1 - 0.0027 17.5 4.7 0.0044 16.8 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KII94821.1 - 0.0076 16.3 3.7 0.061 13.4 3.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KII94821.1 - 0.031 14.4 1.3 0.031 14.4 1.3 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KII94821.1 - 0.12 12.4 2.4 0.32 11.0 2.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KII94821.1 - 1.9 8.3 5.0 6.2 6.7 0.2 3.0 3 0 0 3 3 3 0 RING-like zinc finger tRNA-synt_2c PF01411.19 KII94822.1 - 1.2e-05 24.1 0.0 1.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) MFS_1 PF07690.16 KII94823.1 - 3e-34 118.5 34.0 3e-34 118.5 34.0 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosidase_ig PF17786.1 KII94824.1 - 2.1e-17 63.5 0.1 7.4e-17 61.7 0.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KII94824.1 - 3e-06 27.9 0.0 1.7e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KII94824.1 - 4.5e-05 23.4 0.3 0.00022 21.2 0.1 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KII94824.1 - 0.0032 17.2 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KII94824.1 - 0.071 12.2 0.1 0.25 10.4 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ras PF00071.22 KII94825.1 - 5.5e-45 152.9 0.0 6.3e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KII94825.1 - 6e-16 58.7 0.0 8.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII94825.1 - 1.2e-06 28.1 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KII94825.1 - 0.0003 20.4 0.1 0.0011 18.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KII94825.1 - 0.00098 19.1 0.1 0.54 10.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KII94825.1 - 0.001 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KII94825.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Spo12 PF05032.12 KII94827.1 - 1.1e-15 57.2 0.4 1.1e-15 57.2 0.4 2.1 3 0 0 3 3 3 1 Spo12 family Polyketide_cyc PF03364.20 KII94828.1 - 3.5e-20 72.5 0.0 4.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Chitin_synth_1 PF01644.17 KII94830.1 - 8.2e-67 224.2 0.0 1.3e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KII94830.1 - 1.3e-29 102.0 0.1 3e-29 100.8 0.1 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KII94830.1 - 3.1e-21 75.6 0.1 2.3e-18 66.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KII94830.1 - 7.1e-07 29.3 7.4 5.8e-06 26.3 7.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 zf-RING_2 PF13639.6 KII94831.1 - 4.7e-06 26.8 3.7 5.2e-05 23.5 1.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KII94831.1 - 5.2e-06 26.3 1.6 0.00026 20.9 1.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KII94831.1 - 7.7e-06 25.7 2.3 0.00012 21.9 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII94831.1 - 1.1e-05 25.2 1.9 4.7e-05 23.2 1.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII94831.1 - 3.5e-05 23.6 3.2 0.00061 19.6 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII94831.1 - 7.6e-05 22.5 4.3 0.00027 20.7 1.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KII94831.1 - 0.00029 20.8 5.2 0.00034 20.6 1.2 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KII94831.1 - 0.00074 19.7 6.5 0.0038 17.5 6.6 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C2HC5 PF06221.13 KII94831.1 - 0.0029 17.5 0.3 0.043 13.8 0.1 2.2 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-Nse PF11789.8 KII94831.1 - 0.0043 16.8 0.7 0.02 14.7 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KII94831.1 - 0.01 15.6 1.3 0.085 12.7 0.4 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KII94831.1 - 0.014 15.5 1.3 0.014 15.5 1.3 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KII94831.1 - 0.016 15.2 1.2 0.037 14.1 0.5 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KII94831.1 - 0.064 13.1 0.3 0.82 9.6 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 KII94831.1 - 0.096 13.0 1.5 5.8 7.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon Pellino PF04710.14 KII94831.1 - 0.1 11.3 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Pellino DUF5446 PF17522.2 KII94831.1 - 0.47 10.7 5.2 0.18 12.0 1.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) zf-CCHC PF00098.23 KII94832.1 - 7.7e-34 114.3 46.9 4e-07 29.8 2.6 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KII94832.1 - 1.4e-11 43.9 25.9 0.0012 18.5 0.9 6.0 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.6 KII94832.1 - 0.0027 17.6 31.7 2 8.5 0.7 6.1 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_6 PF15288.6 KII94832.1 - 0.0037 17.1 39.3 0.0071 16.2 2.8 5.6 4 2 1 5 5 5 5 Zinc knuckle Mu-like_Com PF10122.9 KII94832.1 - 0.0051 16.2 13.1 0.56 9.7 0.1 4.3 4 0 0 4 4 4 3 Mu-like prophage protein Com zf-CCHC_5 PF14787.6 KII94832.1 - 2.4 7.9 29.0 0.79 9.5 0.8 5.7 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger Aminotran_1_2 PF00155.21 KII94834.1 - 1.2e-14 54.3 0.0 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II 14-3-3 PF00244.20 KII94836.1 - 8e-75 251.1 0.1 9.1e-75 251.0 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DS PF01916.17 KII94837.1 - 2.5e-135 450.3 0.0 2.9e-135 450.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.20 KII94838.1 - 1.4e-69 233.4 0.1 3.1e-69 232.4 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KII94838.1 - 1.1e-46 158.6 8.4 4.3e-46 156.7 3.7 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KII94838.1 - 7.6e-33 112.2 0.2 7.6e-33 112.2 0.2 5.5 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KII94838.1 - 1.7e-21 76.7 2.3 2.1e-18 66.6 0.0 3.9 4 0 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1539 PF07560.11 KII94838.1 - 0.0056 16.8 0.1 1.3 9.1 0.0 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) HEAT PF02985.22 KII94838.1 - 0.069 13.4 0.0 1.4 9.4 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat SH3_1 PF00018.28 KII94839.1 - 1.8e-40 136.3 6.8 2.7e-14 52.5 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KII94839.1 - 6.7e-37 125.1 8.8 1.1e-12 47.6 0.4 4.1 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 KII94839.1 - 1e-31 108.6 0.0 2.4e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KII94839.1 - 4.3e-28 96.8 0.0 8.4e-08 31.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 KII94839.1 - 2.6e-05 24.4 3.2 0.24 11.7 0.2 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain hSH3 PF14603.6 KII94839.1 - 0.00042 20.7 0.0 0.83 10.1 0.0 2.7 2 0 0 2 2 2 2 Helically-extended SH3 domain SAM_4 PF18017.1 KII94839.1 - 0.00046 20.1 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KII94839.1 - 0.0016 18.4 0.0 6.7 6.9 0.0 3.5 3 0 0 3 3 3 1 SH3 domain GREB1 PF15782.5 KII94839.1 - 0.83 6.7 7.0 1.5 5.8 7.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Coilin_N PF15862.5 KII94839.1 - 2.6 7.8 16.8 5.9 6.7 10.1 3.9 3 1 0 3 3 3 0 Coilin N-terminus GTP_EFTU PF00009.27 KII94840.1 - 1.4e-44 151.9 0.0 1.9e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KII94840.1 - 9.2e-34 116.1 0.0 3.1e-33 114.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KII94840.1 - 5.5e-10 39.5 0.1 1.3e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KII94840.1 - 0.0024 17.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KII94840.1 - 0.0076 16.3 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.10 KII94840.1 - 6.6 6.0 6.6 9.8 5.4 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-MYND PF01753.18 KII94842.1 - 0.026 14.6 14.2 0.026 14.6 14.2 1.8 2 0 0 2 2 2 0 MYND finger BRCT_2 PF16589.5 KII94844.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KII94844.1 - 2.1e-06 28.0 0.0 6.3e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KII94844.1 - 6.7e-06 25.9 0.3 4.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KII94844.1 - 0.0015 18.8 0.1 0.0033 17.7 0.1 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KII94844.1 - 0.014 15.4 0.0 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain CAF1A PF12253.8 KII94845.1 - 0.068 13.3 3.2 0.18 12.0 3.2 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Gp-FAR-1 PF05823.12 KII94846.1 - 3.2e-06 27.6 0.0 5.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ATG16 PF08614.11 KII94846.1 - 0.027 14.7 0.9 0.14 12.4 0.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) B5 PF03484.15 KII94846.1 - 0.036 14.4 2.9 0.15 12.3 2.9 2.2 1 1 0 1 1 1 0 tRNA synthetase B5 domain DUF4769 PF15992.5 KII94846.1 - 0.044 13.6 0.4 0.067 13.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) ApoLp-III PF07464.11 KII94846.1 - 0.074 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Mur_ligase_M PF08245.12 KII94848.1 - 2.2e-06 27.8 0.1 0.0017 18.4 0.0 2.8 1 1 1 2 2 2 2 Mur ligase middle domain Slx4 PF09494.10 KII94849.1 - 2e-08 34.0 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease IBN_N PF03810.19 KII94850.1 - 5.8e-06 26.1 0.2 0.00047 20.0 0.0 3.5 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KII94850.1 - 0.00056 20.0 0.0 0.0073 16.4 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 KII94850.1 - 0.0077 16.6 0.3 0.052 13.9 0.1 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KII94850.1 - 0.053 13.8 0.1 0.44 10.9 0.1 2.7 1 0 0 1 1 1 0 HEAT repeat DUF3385 PF11865.8 KII94850.1 - 0.092 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) F-box-like PF12937.7 KII94851.1 - 1.2e-05 25.1 0.1 3.6e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94851.1 - 0.00012 21.8 0.1 0.0009 19.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII94852.1 - 0.0001 22.1 1.0 0.00039 20.3 0.1 2.5 3 0 0 3 3 3 1 F-box-like AATF-Che1 PF13339.6 KII94852.1 - 0.014 16.1 0.5 0.022 15.4 0.5 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor F-box PF00646.33 KII94852.1 - 0.02 14.7 3.8 0.031 14.2 0.0 2.9 3 0 0 3 3 3 0 F-box domain BUD22 PF09073.10 KII94852.1 - 0.16 11.3 9.9 0.21 10.9 9.9 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 KII94852.1 - 0.46 9.8 15.4 0.69 9.3 15.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KII94852.1 - 0.99 7.6 12.6 1.3 7.2 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KII94852.1 - 2.2 6.3 27.6 3.1 5.8 27.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 KII94852.1 - 2.5 6.6 19.3 3.2 6.2 19.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_ner PF04546.13 KII94852.1 - 6 6.7 12.5 9.7 6.0 12.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 KII94852.1 - 9.5 4.3 19.9 13 3.8 19.9 1.1 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.7 KII94854.1 - 0.00025 20.9 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94854.1 - 0.0081 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.33 KII94855.1 - 0.0036 17.1 0.1 0.012 15.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain BUD22 PF09073.10 KII94855.1 - 5.2 6.3 11.8 7.4 5.8 11.8 1.1 1 0 0 1 1 1 0 BUD22 Peptidase_S28 PF05577.12 KII94856.1 - 6.1e-52 176.9 1.5 1.5e-51 175.5 1.5 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KII94856.1 - 0.00034 20.2 0.1 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family ATP-synt_I PF03899.15 KII94860.1 - 0.94 9.9 12.7 3.9 7.9 4.9 2.8 2 1 0 2 2 2 0 ATP synthase I chain CM_2 PF01817.21 KII94861.1 - 1.2e-05 25.6 0.0 0.031 14.6 0.0 2.7 2 1 0 2 2 2 2 Chorismate mutase type II Acetyltransf_1 PF00583.25 KII94862.1 - 6e-12 45.8 0.0 1.2e-11 44.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII94862.1 - 3.9e-09 36.8 0.1 1.4e-08 35.0 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII94862.1 - 6.9e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII94862.1 - 1.9e-06 27.7 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KII94862.1 - 0.00074 20.2 0.0 0.0026 18.4 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KII94862.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KII94862.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KII94862.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ThrE PF06738.12 KII94863.1 - 5.2e-42 143.9 18.7 7.6e-42 143.3 4.4 2.3 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KII94863.1 - 4.3e-05 23.7 7.0 4.3e-05 23.7 7.0 3.0 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE tRNA-synt_2d PF01409.20 KII94864.1 - 3.7e-83 278.8 0.0 2.4e-54 184.4 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KII94864.1 - 6.8e-18 64.7 1.9 9.7e-18 64.2 0.3 2.2 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KII94864.1 - 2e-09 37.2 0.0 0.00035 20.1 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KII94864.1 - 0.0029 16.8 0.7 0.03 13.4 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KII94864.1 - 0.0073 16.3 0.3 0.0073 16.3 0.3 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 KII94864.1 - 0.035 14.1 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) MFS_1 PF07690.16 KII94865.1 - 1.7e-18 66.7 50.3 2.3e-09 36.6 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4663 PF15668.5 KII94867.1 - 2 7.4 4.6 2.5 7.1 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Btz PF09405.10 KII94868.1 - 4.8e-08 33.3 9.3 4.8e-08 33.3 9.3 2.5 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Abhydrolase_1 PF00561.20 KII94869.1 - 2.7e-26 92.8 0.0 6.5e-21 75.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII94869.1 - 5.7e-16 59.8 0.1 8e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII94869.1 - 4.3e-11 42.5 0.0 3.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KII94869.1 - 2.1e-05 23.4 0.0 3.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 KII94870.1 - 4.2e-53 180.7 1.2 3.4e-52 177.7 1.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KII94870.1 - 0.00095 18.7 0.9 0.0032 17.0 0.9 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF4091 PF13320.6 KII94870.1 - 0.053 13.6 0.0 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) WD40 PF00400.32 KII94871.1 - 1.4e-08 35.2 10.6 0.45 11.5 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII94871.1 - 5.5e-07 29.8 0.1 0.0097 16.2 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KII94871.1 - 8.2e-05 22.4 0.7 0.27 11.2 0.0 3.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KII94871.1 - 0.00032 20.7 0.0 0.35 10.7 0.0 3.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KII94871.1 - 0.035 12.6 0.0 0.11 11.0 0.0 1.8 1 1 1 2 2 2 0 Cytochrome D1 heme domain F-box-like PF12937.7 KII94873.1 - 0.00078 19.3 0.7 0.0022 17.8 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII94873.1 - 0.0047 16.8 0.6 0.042 13.7 0.6 2.6 2 1 1 3 3 3 1 F-box domain Pex2_Pex12 PF04757.14 KII94874.1 - 1.1e-32 113.4 7.4 1.5e-32 113.0 7.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KII94874.1 - 0.00019 21.4 1.3 0.00019 21.4 1.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KII94874.1 - 0.00066 19.8 1.4 0.0021 18.2 1.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KII94874.1 - 0.0023 17.9 2.5 0.0032 17.5 0.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 KII94874.1 - 0.0033 17.6 0.2 0.0061 16.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4 PF00097.25 KII94874.1 - 0.0044 16.9 2.6 0.015 15.1 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII94874.1 - 0.014 15.2 0.6 0.014 15.2 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII94874.1 - 0.021 15.1 4.8 0.042 14.2 1.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 KII94874.1 - 0.073 13.4 1.2 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KII94874.1 - 0.081 12.8 3.6 0.4 10.6 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HpcH_HpaI PF03328.14 KII94874.1 - 0.23 10.6 0.0 1.1 8.3 0.0 1.9 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Prok-RING_4 PF14447.6 KII94874.1 - 0.62 10.0 3.0 0.51 10.2 0.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FYVE PF01363.21 KII94874.1 - 0.93 9.7 3.4 0.84 9.8 0.8 2.0 2 0 0 2 2 2 0 FYVE zinc finger THOC7 PF05615.13 KII94875.1 - 1.7e-33 115.7 4.9 1.7e-33 115.7 4.9 1.5 2 0 0 2 2 1 1 Tho complex subunit 7 Filament PF00038.21 KII94875.1 - 0.00057 19.6 6.4 0.00089 18.9 6.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein Golgin_A5 PF09787.9 KII94875.1 - 0.0035 16.9 7.4 0.0053 16.3 7.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Syntaxin PF00804.25 KII94875.1 - 0.042 13.5 6.3 0.073 12.7 6.3 1.3 1 0 0 1 1 1 0 Syntaxin FlaC_arch PF05377.11 KII94875.1 - 0.047 14.1 4.1 1.4 9.4 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.13 KII94875.1 - 0.078 13.4 4.4 9.8 6.7 1.8 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KII94875.1 - 0.081 13.0 2.5 0.42 10.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 KII94875.1 - 0.083 13.1 4.5 1.3 9.3 0.7 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF4515 PF14988.6 KII94875.1 - 0.31 10.8 9.5 0.49 10.2 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) TolA_bind_tri PF16331.5 KII94875.1 - 0.39 10.8 10.9 0.16 12.1 6.3 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation CENP-Q PF13094.6 KII94875.1 - 1 9.5 10.5 0.06 13.5 4.9 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HIP1_clath_bdg PF16515.5 KII94875.1 - 1.3 9.7 9.2 13 6.5 0.3 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 KII94875.1 - 1.6 8.5 6.9 13 5.7 2.1 2.3 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 KII94875.1 - 3.4 7.7 10.3 16 5.6 0.4 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.6 KII94875.1 - 4.9 7.6 8.2 16 6.0 1.3 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.6 KII94875.1 - 8.7 6.8 9.7 12 6.4 3.9 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Lactamase_B_2 PF12706.7 KII94876.1 - 4e-12 46.1 0.1 9e-05 22.1 0.0 3.6 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KII94876.1 - 4.5e-05 23.5 0.1 9.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 KII94876.1 - 0.00086 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease Glyco_hydro_3_C PF01915.22 KII94877.1 - 1e-47 162.7 0.2 1e-47 162.7 0.2 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KII94877.1 - 5.3e-24 84.1 0.1 1.1e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 KII94877.1 - 2.1e-19 70.0 0.0 7.1e-19 68.3 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain LRR_6 PF13516.6 KII94878.1 - 1.1e-12 46.9 3.0 0.96 9.7 0.2 7.3 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 KII94878.1 - 4.6e-11 42.8 3.7 0.28 11.7 0.0 6.9 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KII94878.1 - 6.7e-05 22.9 6.6 33 5.6 0.4 7.0 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KII94878.1 - 0.21 11.4 3.5 11 5.9 0.4 4.4 4 2 0 4 4 4 0 Leucine rich repeat RhoGEF PF00621.20 KII94879.1 - 4.7e-18 66.1 0.0 8.2e-14 52.2 0.0 3.0 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.29 KII94879.1 - 0.005 17.3 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 PH domain RhoGEF PF00621.20 KII94880.1 - 1.1e-33 117.0 0.0 3.1e-33 115.6 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Kre28 PF17097.5 KII94880.1 - 0.0037 16.3 7.0 0.0072 15.3 7.0 1.4 1 0 0 1 1 1 1 Spindle pole body component DUF3496 PF12001.8 KII94880.1 - 0.85 10.0 4.7 2 8.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) zf-C3HC4_3 PF13920.6 KII94881.1 - 2.5e-07 30.4 11.2 3.9e-07 29.8 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII94881.1 - 8.4e-05 22.4 11.3 0.00015 21.7 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 KII94881.1 - 9.7e-05 22.1 7.7 0.0098 15.7 6.0 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KII94881.1 - 0.00011 21.9 11.1 0.0044 16.9 11.5 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KII94881.1 - 0.00012 22.4 12.3 0.00019 21.7 12.3 1.3 1 0 0 1 1 1 1 Ring finger domain TMF_DNA_bd PF12329.8 KII94881.1 - 0.00049 20.0 3.8 0.00049 20.0 3.8 3.8 4 0 0 4 4 4 1 TATA element modulatory factor 1 DNA binding zf-C3HC4_2 PF13923.6 KII94881.1 - 0.00054 19.8 12.8 0.0009 19.0 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII94881.1 - 0.0012 18.7 12.0 0.002 18.0 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GAS PF13851.6 KII94881.1 - 0.0037 16.7 7.6 0.0037 16.7 7.6 1.7 2 0 0 2 2 1 1 Growth-arrest specific micro-tubule binding Spt4 PF06093.13 KII94881.1 - 0.013 15.6 4.1 0.016 15.3 0.2 2.4 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger zf-RING_UBOX PF13445.6 KII94881.1 - 0.025 14.6 11.0 0.044 13.8 11.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger DNA_ligase_ZBD PF03119.16 KII94881.1 - 0.06 13.4 2.8 0.97 9.5 0.1 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain CorA PF01544.18 KII94881.1 - 0.71 9.1 2.7 1.1 8.6 2.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C3HC4_5 PF17121.5 KII94881.1 - 1.7 8.6 13.1 6.1 6.8 13.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4201 PF13870.6 KII94881.1 - 1.7 8.4 19.0 0.038 13.7 6.6 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4201) DZR PF12773.7 KII94881.1 - 2 8.5 11.1 21 5.2 11.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon TSC22 PF01166.18 KII94881.1 - 2.8 8.3 7.1 11 6.4 0.1 3.4 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF3138 PF11336.8 KII94881.1 - 3.3 6.2 3.6 5.4 5.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-WRNIP1_ubi PF18279.1 KII94881.1 - 3.4 8.5 4.8 40 5.2 0.2 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_10 PF16685.5 KII94881.1 - 4.9 7.4 9.5 9.9 6.4 9.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KII94881.1 - 7.1 6.9 13.7 14 6.0 13.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2052 PF09747.9 KII94882.1 - 5.3e-09 36.5 18.9 1.1e-08 35.5 18.9 1.6 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF5310 PF17237.2 KII94883.1 - 2e-18 66.0 4.7 2.7e-18 65.5 4.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Vps55 PF04133.14 KII94883.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DNase_NucA_NucB PF14040.6 KII94884.1 - 3.6e-07 30.5 0.6 1.5e-06 28.5 0.6 2.0 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB DNase_NucA_NucB PF14040.6 KII94885.1 - 7.5e-09 36.0 1.3 1e-07 32.3 0.4 2.6 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB Myb_DNA-binding PF00249.31 KII94886.1 - 1e-21 76.8 9.9 2.2e-10 40.6 0.1 4.8 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII94886.1 - 2.5e-14 53.3 11.6 2.9e-08 33.8 0.1 4.1 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KII94886.1 - 0.0062 16.9 1.3 0.0062 16.9 1.3 3.6 2 2 1 3 3 3 1 Myb/SANT-like DNA-binding domain MbeD_MobD PF04899.12 KII94886.1 - 0.023 14.8 0.1 0.08 13.1 0.1 1.9 1 0 0 1 1 1 0 MbeD/MobD like Rap1_C PF11626.8 KII94886.1 - 0.039 14.0 0.0 1.7 8.8 0.0 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 KII94886.1 - 2.7 8.2 5.2 7.4 6.8 0.1 2.9 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF629 PF04780.12 KII94888.1 - 0.15 10.6 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) AAA PF00004.29 KII94889.1 - 3.5e-19 69.5 0.0 6.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KII94889.1 - 0.041 13.9 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KII94889.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SANT_DAMP1_like PF16282.5 KII94890.1 - 1.2e-31 108.7 5.7 2.1e-31 108.0 5.7 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 KII94890.1 - 0.00014 22.0 0.5 0.00048 20.3 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KII94890.1 - 0.0017 18.5 0.5 0.009 16.2 0.1 2.4 2 1 1 3 3 3 1 Myb-like DNA-binding domain DUF202 PF02656.15 KII94891.1 - 7.5e-16 58.3 1.3 7.5e-16 58.3 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) 7tm_6 PF02949.20 KII94891.1 - 0.065 12.3 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 7tm Odorant receptor zf-U1 PF06220.12 KII94892.1 - 2.6e-20 71.9 5.8 3.5e-20 71.5 5.8 1.2 1 0 0 1 1 1 1 U1 zinc finger LSM PF01423.22 KII94893.1 - 4.4e-19 67.9 0.0 5.4e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KII94893.1 - 0.094 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain F-box-like PF12937.7 KII94895.1 - 2.2e-11 43.5 2.6 2.2e-11 43.5 2.6 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII94895.1 - 1.6e-05 25.2 11.2 0.24 11.9 0.0 6.7 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KII94895.1 - 0.0012 18.7 18.5 32 4.9 0.0 10.2 11 0 0 11 11 11 1 Leucine Rich repeat F-box PF00646.33 KII94895.1 - 0.017 15.0 1.6 0.017 15.0 1.6 4.8 4 0 0 4 4 4 0 F-box domain Acetyltransf_1 PF00583.25 KII94896.1 - 4.4e-13 49.5 0.0 5.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KII94896.1 - 9.1e-10 38.6 0.0 1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII94896.1 - 1.9e-06 28.2 0.0 2.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII94896.1 - 4.9e-05 23.2 0.0 6.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KII94896.1 - 0.03 13.8 0.3 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KII94896.1 - 0.032 14.3 0.2 0.052 13.6 0.2 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF676 PF05057.14 KII94897.1 - 3.2e-07 30.1 0.0 7.1e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KII94897.1 - 3.3e-05 24.6 1.8 6.6e-05 23.6 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KII94897.1 - 0.0019 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.12 KII94897.1 - 0.0037 16.8 0.0 0.02 14.4 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 KII94897.1 - 0.0043 16.9 0.3 0.008 16.0 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII94897.1 - 0.0079 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 KII94897.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase2 PF12740.7 KII94897.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 KII94897.1 - 0.019 14.7 0.1 0.035 13.8 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 KII94897.1 - 0.029 13.9 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 KII94897.1 - 0.22 10.8 0.0 15 4.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Aldolase_II PF00596.21 KII94899.1 - 4.2e-51 173.5 0.0 5.2e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TUG-UBL1 PF11470.8 KII94899.1 - 0.13 12.5 0.4 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain tRNA-synt_1c PF00749.21 KII94900.1 - 1e-106 356.4 0.0 1.3e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KII94900.1 - 1.7e-36 125.7 0.2 2.7e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KII94900.1 - 5e-33 114.4 0.0 1e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KII94900.1 - 4.5e-05 24.3 0.9 4.5e-05 24.3 0.9 2.5 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Lactamase_B_6 PF16661.5 KII94901.1 - 7e-50 169.2 0.0 4.5e-49 166.5 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KII94901.1 - 2.7e-26 92.8 11.2 1e-24 87.6 0.0 4.4 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KII94901.1 - 7.6e-21 74.5 0.0 2.3e-19 69.7 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KII94901.1 - 0.00022 21.1 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain DUF1772 PF08592.11 KII94902.1 - 1.1e-23 84.1 0.7 1.6e-23 83.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1422 PF07226.11 KII94902.1 - 0.024 14.6 0.1 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Sugar_tr PF00083.24 KII94902.1 - 0.067 12.0 1.4 0.18 10.7 0.0 1.9 1 1 1 2 2 2 0 Sugar (and other) transporter PAF-AH_p_II PF03403.13 KII94903.1 - 1e-28 100.0 0.0 2.2e-28 98.9 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KII94903.1 - 6.7e-05 22.3 0.0 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KII94903.1 - 0.00017 20.6 0.0 0.064 12.2 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.11 KII94903.1 - 0.023 13.7 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Say1_Mug180 PF10340.9 KII94903.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase GPI-anchored PF10342.9 KII94906.1 - 0.0024 18.6 0.0 0.0046 17.7 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KII94906.1 - 0.0038 17.0 0.2 0.0049 16.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GFA PF04828.14 KII94907.1 - 3.8e-23 81.6 1.2 4.6e-23 81.4 0.5 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KII94907.1 - 0.039 14.1 1.8 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Rpr2 PF04032.16 KII94907.1 - 0.11 12.8 1.3 0.24 11.7 0.1 2.0 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Auto_anti-p27 PF06677.12 KII94907.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) BTB PF00651.31 KII94908.1 - 0.00047 20.4 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2828 PF11443.8 KII94909.1 - 0.0096 14.1 3.4 0.013 13.7 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF5305 PF17231.2 KII94909.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Connexin PF00029.19 KII94909.1 - 0.05 13.4 1.4 0.089 12.5 1.4 1.3 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 KII94909.1 - 0.13 10.2 0.7 0.17 9.7 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.10 KII94909.1 - 0.15 12.1 1.0 0.26 11.4 1.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4834 PF16118.5 KII94909.1 - 0.17 12.9 0.3 0.17 12.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) 7tm_1 PF00001.21 KII94909.1 - 0.22 10.8 0.0 0.22 10.8 0.0 1.4 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Merozoite_SPAM PF07133.11 KII94909.1 - 1.1 9.2 11.8 9.5 6.2 10.9 2.0 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 KII94909.1 - 2.6 6.2 11.0 3.7 5.7 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DIOX_N PF14226.6 KII94910.1 - 3.2e-26 92.4 0.1 5.3e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII94910.1 - 7.4e-18 64.9 0.0 2.3e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Orthoreo_P10 PF07204.11 KII94911.1 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Phage_holin_2_1 PF04971.12 KII94911.1 - 0.04 13.9 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage P21 holin S RCC1 PF00415.18 KII94912.1 - 3.8e-64 213.1 16.2 2.3e-12 47.4 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KII94912.1 - 1.1e-35 120.7 38.7 2.5e-08 33.5 1.5 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 KII94912.1 - 0.029 14.2 2.3 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 PapC C-terminal domain Hira PF07569.11 KII94912.1 - 0.051 13.3 0.1 11 5.7 0.1 2.8 3 1 0 3 3 3 0 TUP1-like enhancer of split Aldedh PF00171.22 KII94913.1 - 2.9e-148 494.2 0.1 3.5e-148 494.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KII94913.1 - 0.012 14.6 0.1 0.027 13.5 0.1 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) S4 PF01479.25 KII94913.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 S4 domain Snf7 PF03357.21 KII94914.1 - 1.6e-44 151.6 12.6 1.8e-44 151.4 12.6 1.0 1 0 0 1 1 1 1 Snf7 DUF5344 PF17279.2 KII94914.1 - 0.022 15.3 6.4 0.18 12.4 2.8 3.0 1 1 0 2 2 2 0 Family of unknown function (DUF5344) Prefoldin_2 PF01920.20 KII94914.1 - 0.022 14.7 9.2 1.3 9.0 0.0 3.4 2 1 1 3 3 3 0 Prefoldin subunit WbqC PF08889.11 KII94914.1 - 0.048 13.6 0.6 0.057 13.3 0.6 1.1 1 0 0 1 1 1 0 WbqC-like protein family NPV_P10 PF05531.12 KII94914.1 - 0.09 13.3 1.8 3.8 8.0 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KII94914.1 - 0.42 11.0 5.8 1.4 9.4 0.0 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KII94914.1 - 0.48 10.9 14.2 1.8 9.1 1.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FlxA PF14282.6 KII94914.1 - 2 8.4 9.3 0.55 10.2 4.3 2.4 1 1 1 2 2 2 0 FlxA-like protein Abhydrolase_1 PF00561.20 KII94917.1 - 9.9e-43 146.6 0.0 3.2e-42 145.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KII94917.1 - 4.8e-05 23.1 0.1 7.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KII94917.1 - 0.026 13.8 0.0 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KII94917.1 - 0.19 11.5 0.1 0.7 9.7 0.1 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Snf7 PF03357.21 KII94919.1 - 3.1e-12 46.4 13.3 4.1e-12 46.0 13.3 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 KII94919.1 - 0.0016 18.1 1.0 0.003 17.2 0.0 1.8 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 KII94919.1 - 0.014 15.3 3.5 0.023 14.7 3.5 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ANAPC2 PF08672.11 KII94919.1 - 0.12 12.8 1.0 3.2 8.3 1.0 2.6 1 1 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 DUF2857 PF11198.8 KII94919.1 - 0.14 11.9 3.1 0.24 11.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) T7SS_ESX_EspC PF10824.8 KII94919.1 - 0.86 10.1 6.7 0.42 11.1 0.4 3.2 2 1 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm T2SSM PF04612.12 KII94919.1 - 5.2 7.1 8.7 0.69 10.0 0.4 2.4 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Erv26 PF04148.13 KII94920.1 - 6.5e-65 218.8 4.8 7.8e-65 218.6 4.8 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 KII94920.1 - 0.0024 17.8 0.6 0.0052 16.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) BTB PF00651.31 KII94921.1 - 0.086 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain Syja_N PF02383.18 KII94922.1 - 7e-75 252.3 0.0 9.5e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF3449 PF11931.8 KII94923.1 - 9.4e-74 247.2 0.2 9.4e-74 247.2 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KII94923.1 - 5.3e-23 81.3 4.7 7.5e-23 80.9 2.7 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KII94923.1 - 1.7e-08 34.2 0.3 3.7e-08 33.1 0.3 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 KII94923.1 - 6.5e-07 29.5 1.1 6.5e-07 29.5 1.1 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KII94923.1 - 5.2e-06 26.7 8.1 1.3e-05 25.4 2.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KII94923.1 - 0.0013 19.0 0.8 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 KII94923.1 - 0.031 14.4 3.4 1.6 8.9 0.1 2.8 2 0 0 2 2 2 0 DBF zinc finger Jas PF16135.5 KII94923.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling Laps PF10169.9 KII94923.1 - 0.096 13.3 1.1 0.36 11.4 0.2 2.5 3 0 0 3 3 3 0 Learning-associated protein Jnk-SapK_ap_N PF09744.9 KII94923.1 - 4.2 7.6 11.9 0.12 12.6 4.8 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 zf-C2H2_4 PF13894.6 KII94923.1 - 6.2 7.9 8.2 33 5.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DEAD PF00270.29 KII94924.1 - 2.4e-43 147.9 0.1 4e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KII94924.1 - 2.9e-31 108.1 0.1 1.1e-30 106.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KII94924.1 - 0.00041 20.7 0.1 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KII94924.1 - 0.0009 19.3 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KII94924.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KII94924.1 - 0.072 13.4 0.6 0.42 10.9 0.6 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KII94924.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DNA_III_psi PF03603.13 KII94924.1 - 0.17 12.2 0.1 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase III psi subunit Glyco_trans_4_3 PF12000.8 KII94925.1 - 0.093 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 4 group RRM_1 PF00076.22 KII94926.1 - 1.2e-18 66.7 0.1 1.2e-18 66.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII94926.1 - 7.6e-09 35.2 0.0 8.5e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KII94926.1 - 0.026 14.7 0.0 0.054 13.7 0.0 1.5 1 1 1 2 2 2 0 RRM-like domain RRM_3 PF08777.11 KII94926.1 - 0.039 14.0 0.1 0.062 13.4 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 KII94926.1 - 0.14 12.1 0.1 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Wtap PF17098.5 KII94927.1 - 0.007 16.3 0.3 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 WTAP/Mum2p family SUIM_assoc PF16619.5 KII94928.1 - 1.6 8.8 9.6 2.8 8.1 9.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RNA_pol_Rpb1_5 PF04998.17 KII94929.1 - 1.3e-84 283.8 0.0 2e-84 283.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KII94929.1 - 8.3e-65 218.0 0.9 4.8e-64 215.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KII94929.1 - 3.8e-36 124.4 0.0 1.2e-35 122.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KII94929.1 - 1e-30 107.1 0.2 6.8e-25 88.0 0.0 3.0 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KII94929.1 - 6.7e-21 74.3 0.0 1.7e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF5102 PF17104.5 KII94931.1 - 6.9e-70 236.4 0.1 9.3e-70 235.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) CENP-Q PF13094.6 KII94931.1 - 0.02 15.1 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RIX1 PF08167.12 KII94932.1 - 3.6e-38 131.2 7.8 6.7e-38 130.3 2.8 2.2 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis Sec10 PF07393.11 KII94933.1 - 5.5e-229 762.3 0.1 7e-229 761.9 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 I_LWEQ PF01608.17 KII94933.1 - 0.028 14.6 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 I/LWEQ domain GNAT_like PF18407.1 KII94933.1 - 0.66 10.4 4.2 0.38 11.1 0.1 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain Abhydrolase_3 PF07859.13 KII94934.1 - 6.8e-40 137.2 0.0 3.9e-31 108.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII94934.1 - 5.7e-11 41.9 0.0 1.9e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KII94934.1 - 0.032 13.5 0.0 0.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COesterase PF00135.28 KII94934.1 - 0.098 11.5 0.1 0.23 10.3 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Tubulin PF00091.25 KII94935.1 - 1.2e-65 221.4 0.0 1.6e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KII94935.1 - 7.8e-47 158.6 0.0 1.3e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KII94935.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KII94935.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin PF00091.25 KII94936.1 - 8.1e-66 222.0 0.0 1.1e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KII94936.1 - 1.8e-46 157.4 0.0 2.8e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KII94936.1 - 0.00088 19.0 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 KII94936.1 - 0.047 13.5 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) HAD_2 PF13419.6 KII94937.1 - 1.3e-14 54.7 0.0 1.8e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KII94937.1 - 3.8e-08 33.9 0.1 1e-06 29.2 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII94937.1 - 1.4e-07 31.4 0.1 4e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Sec15 PF04091.12 KII94938.1 - 1.7e-102 343.1 3.2 3.5e-102 342.1 3.2 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KII94938.1 - 1.2e-07 32.0 0.6 1.2e-07 32.0 0.6 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KII94938.1 - 1.3e-06 28.4 0.2 1.3e-06 28.4 0.2 2.7 3 0 0 3 3 3 1 Vps51/Vps67 Sec8_exocyst PF04048.14 KII94938.1 - 0.00016 21.6 6.3 0.00016 21.5 0.3 3.3 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Prominin PF05478.11 KII94938.1 - 0.0019 16.3 3.3 0.029 12.3 0.1 2.3 2 0 0 2 2 2 2 Prominin COG2 PF06148.11 KII94938.1 - 0.019 15.0 6.5 0.053 13.6 1.3 3.7 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RAC_head PF16717.5 KII94938.1 - 0.22 12.5 2.5 1 10.3 0.4 3.2 3 1 1 4 4 4 0 Ribosome-associated complex head domain Arf PF00025.21 KII94939.1 - 3.2e-79 264.4 0.1 3.6e-79 264.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KII94939.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KII94939.1 - 3.1e-14 52.8 0.0 3.8e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KII94939.1 - 6.4e-13 48.6 1.3 4e-09 36.1 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KII94939.1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KII94939.1 - 1.4e-10 41.0 0.0 1.7e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII94939.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KII94939.1 - 0.0066 15.8 0.6 0.018 14.4 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DSPc PF00782.20 KII94940.1 - 1.2e-27 96.4 0.0 1.4e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII94940.1 - 1.8e-05 24.4 0.0 2.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KII94940.1 - 0.0099 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF2076 PF09849.9 KII94942.1 - 0.0059 16.7 2.7 0.0082 16.2 2.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF3245 PF11595.8 KII94943.1 - 1.6e-07 31.9 0.1 1.6e-07 31.9 0.1 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF3245) NOP19 PF10863.8 KII94943.1 - 0.0041 17.0 0.0 0.0041 17.0 0.0 3.0 4 0 0 4 4 4 1 Nucleolar protein 19 G-patch_2 PF12656.7 KII94943.1 - 0.13 12.4 1.0 0.88 9.7 0.0 2.7 2 0 0 2 2 2 0 G-patch domain SIP1 PF04938.12 KII94944.1 - 3.9e-25 88.8 0.4 5.5e-25 88.4 0.4 1.2 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) HD-ZIP_N PF04618.12 KII94944.1 - 0.025 15.1 0.1 2.8 8.5 0.0 2.5 2 0 0 2 2 2 0 HD-ZIP protein N terminus Acetyltransf_7 PF13508.7 KII94945.1 - 6.8e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KII94945.1 - 2.1e-06 27.7 0.0 3.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII94945.1 - 6.8e-05 22.8 0.0 0.0065 16.4 0.0 3.0 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_1 PF00583.25 KII94945.1 - 0.00032 20.9 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KII94945.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4208 PF13907.6 KII94945.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) GPI-anchored PF10342.9 KII94946.1 - 4.6e-13 49.7 0.4 6.9e-13 49.2 0.4 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family QRPTase_C PF01729.19 KII94947.1 - 6.8e-49 165.9 0.1 8.4e-49 165.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KII94947.1 - 1e-20 73.5 0.0 2.8e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SBD_N PF07005.11 KII94947.1 - 0.037 13.7 0.1 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Sugar-binding N-terminal domain Methyltransf_11 PF08241.12 KII94948.1 - 3.2e-14 53.4 0.0 5.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII94948.1 - 1e-11 45.4 0.0 2.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII94948.1 - 4.1e-05 24.3 0.0 7.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII94948.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KII94948.1 - 0.051 14.6 0.0 0.097 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 KII94949.1 - 1.4e-20 73.6 0.1 4.4e-20 72.0 0.1 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KII94949.1 - 2.1e-16 59.8 0.0 4.4e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KII94949.1 - 7e-06 27.1 0.0 1.5e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KII94949.1 - 0.0042 16.9 0.1 0.015 15.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 KII94949.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain Spermine_synth PF01564.17 KII94950.1 - 6.1e-07 29.0 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_30 PF05430.11 KII94950.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase TFR_dimer PF04253.15 KII94951.1 - 1.1e-21 77.1 1.3 1.1e-19 70.7 0.0 2.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KII94951.1 - 2.2e-12 47.1 0.0 5.3e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KII94951.1 - 7.8e-11 41.8 0.9 2e-10 40.5 0.9 1.8 1 1 0 1 1 1 1 PA domain Jnk-SapK_ap_N PF09744.9 KII94951.1 - 0.08 13.2 2.3 0.18 12.0 2.3 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KII94951.1 - 4.9 7.2 8.8 0.19 11.8 2.9 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RNA_pol_I_TF PF04090.12 KII94953.1 - 9e-09 35.1 0.2 1.3e-06 28.1 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_2 PF07719.17 KII94953.1 - 0.00088 19.2 1.2 11 6.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KII94953.1 - 0.54 11.2 5.5 14 6.8 0.5 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 KII94954.1 - 7.4e-41 139.9 2.0 8.1e-20 71.7 0.0 3.8 4 0 0 4 4 4 3 ABC transporter AAA_21 PF13304.6 KII94954.1 - 2.7e-16 60.2 8.1 0.00012 22.1 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII94954.1 - 2.7e-13 49.9 0.1 0.00022 20.8 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KII94954.1 - 5.4e-09 35.7 1.3 0.00039 20.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KII94954.1 - 9e-06 25.7 0.2 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_23 PF13476.6 KII94954.1 - 3.4e-05 24.4 7.7 0.017 15.7 0.1 3.8 3 1 1 4 4 4 1 AAA domain MMR_HSR1 PF01926.23 KII94954.1 - 7.5e-05 22.8 0.1 0.26 11.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII94954.1 - 8.2e-05 22.6 0.3 0.33 10.8 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 KII94954.1 - 0.0001 22.3 3.3 0.0001 22.3 3.3 1.8 2 0 0 2 2 1 1 ABC transporter AAA_15 PF13175.6 KII94954.1 - 0.0004 20.2 2.7 0.024 14.3 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 KII94954.1 - 0.001 19.4 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 KII94954.1 - 0.0012 19.3 1.3 1.7 9.0 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KII94954.1 - 0.002 18.5 0.0 3.1 8.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KII94954.1 - 0.0036 17.5 1.3 3.2 7.9 0.0 3.0 3 1 0 3 3 2 2 AAA domain NB-ARC PF00931.22 KII94954.1 - 0.0065 15.7 0.2 0.78 8.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KII94954.1 - 0.011 16.0 0.0 2 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KII94954.1 - 0.017 15.4 1.2 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KII94954.1 - 0.024 14.1 0.1 8.7 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KII94954.1 - 0.026 14.4 0.0 4.3 7.2 0.0 3.1 3 0 0 3 3 3 0 NTPase Dynamin_N PF00350.23 KII94954.1 - 0.031 14.3 2.8 5.7 7.0 0.1 3.0 3 1 0 3 3 3 0 Dynamin family AAA_18 PF13238.6 KII94954.1 - 0.037 14.6 0.1 0.99 10.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KII94954.1 - 0.05 13.2 1.7 0.12 11.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KII94954.1 - 0.057 13.5 0.0 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.6 KII94954.1 - 0.083 11.5 4.2 4.7 5.7 0.1 3.0 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 KII94954.1 - 0.11 12.1 0.2 9.6 5.8 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 KII94954.1 - 0.13 12.0 0.2 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KII94954.1 - 0.13 12.2 0.2 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF719 PF05334.13 KII94956.1 - 0.078 13.2 4.6 0.13 12.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) PCB_OB PF17092.5 KII94956.1 - 1.2 10.0 6.1 2 9.2 1.9 2.3 2 0 0 2 2 2 0 Penicillin-binding protein OB-like domain Alpha-amylase_C PF02806.18 KII94957.1 - 3.5e-26 91.5 0.1 1.3e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KII94957.1 - 3e-16 59.5 0.0 7.8e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KII94957.1 - 3.5e-13 49.8 0.0 6.9e-10 39.0 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CRAL_TRIO PF00650.20 KII94958.1 - 4.7e-39 133.7 0.0 6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII94958.1 - 5.6e-05 23.2 0.2 0.0001 22.4 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KII94958.1 - 0.0036 17.5 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Haspin_kinase PF12330.8 KII94959.1 - 1e-55 189.2 0.0 1.5e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DUF4470 PF14737.6 KII94960.1 - 7.2e-10 38.9 0.1 1.7e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Enoyl_reductase PF12241.8 KII94960.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region TPR_2 PF07719.17 KII94960.1 - 0.27 11.4 1.3 5 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Snurportin1 PF11538.8 KII94961.1 - 5.9e-05 23.2 0.4 0.00013 22.1 0.4 1.6 1 0 0 1 1 1 1 Snurportin1 Sld5 PF05916.11 KII94962.1 - 8.4e-21 74.5 0.5 1.1e-20 74.1 0.5 1.2 1 0 0 1 1 1 1 GINS complex protein Pico_P1A PF02226.16 KII94962.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Picornavirus coat protein (VP4) Smim3 PF17307.2 KII94963.1 - 0.087 12.3 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 Small integral membrane protein 3 P21-Arc PF04062.14 KII94964.1 - 3.3e-77 258.4 0.0 3.7e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Metallophos_3 PF14582.6 KII94964.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily NOB1_Zn_bind PF08772.11 KII94965.1 - 5.9e-30 103.2 0.2 9.3e-30 102.6 0.2 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KII94965.1 - 2.3e-28 98.5 0.0 3.9e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KII94965.1 - 0.054 13.2 1.5 0.44 10.3 0.1 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2HC5 PF06221.13 KII94965.1 - 0.085 12.9 2.3 0.16 12.0 2.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type AKNA PF12443.8 KII94965.1 - 0.19 12.4 1.7 0.69 10.6 1.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Nudix_N_2 PF14803.6 KII94965.1 - 0.27 11.2 0.1 0.27 11.2 0.1 1.9 2 0 0 2 2 2 0 Nudix N-terminal Iso_dh PF00180.20 KII94966.1 - 1.1e-122 409.5 0.0 1.3e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ZapB PF06005.12 KII94967.1 - 0.032 14.7 18.6 0.94 10.0 5.6 3.4 2 1 0 2 2 2 0 Cell division protein ZapB FAM76 PF16046.5 KII94967.1 - 0.12 11.7 1.3 0.24 10.7 1.3 1.4 1 0 0 1 1 1 0 FAM76 protein Aida_N PF08910.10 KII94967.1 - 0.25 11.8 1.6 0.58 10.6 1.6 1.5 1 0 0 1 1 1 0 Aida N-terminus Leu_zip PF15294.6 KII94967.1 - 0.57 9.6 12.5 3.1 7.2 12.5 1.9 1 1 0 1 1 1 0 Leucine zipper ADIP PF11559.8 KII94967.1 - 7.3 6.7 16.4 1.7 8.7 4.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TFR_dimer PF04253.15 KII94969.1 - 1.9e-21 76.4 0.0 6.1e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KII94969.1 - 6.5e-18 65.1 0.0 4e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KII94969.1 - 3e-10 40.0 0.1 7e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 PA domain GTP_cyclohydro2 PF00925.20 KII94970.1 - 4.6e-59 198.7 0.0 9.2e-59 197.7 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II DUF2207 PF09972.9 KII94971.1 - 0.22 10.2 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SARAF PF06682.12 KII94971.1 - 0.33 10.6 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Adeno_PIX PF03955.14 KII94971.1 - 5.7 7.2 9.0 1.2 9.4 4.6 1.9 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Mucin PF01456.17 KII94971.1 - 9.1 6.3 21.3 31 4.5 17.8 2.1 1 1 1 2 2 2 0 Mucin-like glycoprotein Pex14_N PF04695.13 KII94972.1 - 3.8e-10 40.7 0.1 3.8e-10 40.7 0.1 3.7 2 2 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF86 PF01934.17 KII94972.1 - 0.21 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 Peptidase_M24 PF00557.24 KII94973.1 - 2.3e-12 47.1 0.0 3.4e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BCAS2 PF05700.11 KII94973.1 - 0.029 14.1 0.7 0.05 13.3 0.7 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) SKN1 PF03935.15 KII94974.1 - 1.5e-177 591.0 1.5 1.8e-177 590.8 1.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) adh_short PF00106.25 KII94976.1 - 2.2e-41 141.5 0.1 3.2e-41 141.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII94976.1 - 4.7e-28 98.3 0.0 6.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII94976.1 - 1.2e-11 44.9 0.8 3e-10 40.3 0.8 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KII94976.1 - 0.038 13.5 0.1 0.07 12.6 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KII94979.1 - 0.0048 15.9 4.4 0.0058 15.6 4.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HemY_N PF07219.13 KII94980.1 - 0.59 10.4 2.5 1 9.6 0.5 2.1 2 0 0 2 2 2 0 HemY protein N-terminus CENP-Q PF13094.6 KII94981.1 - 0.011 15.9 1.6 0.02 15.1 1.6 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SSI PF00720.17 KII94983.1 - 0.0098 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Subtilisin inhibitor-like DUF3619 PF12279.8 KII94988.1 - 0.1 12.9 1.4 0.23 11.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) IncD PF17628.2 KII94992.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.0 2 1 0 2 2 2 0 Inclusion membrane protein D F-box PF00646.33 KII94993.1 - 5.8e-05 22.9 0.2 0.00013 21.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KII94993.1 - 0.0023 17.8 0.3 0.0059 16.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KII94993.1 - 0.079 12.8 0.1 0.079 12.8 0.1 2.2 2 0 0 2 2 2 0 F-box zf-C2H2 PF00096.26 KII94994.1 - 1e-14 54.1 20.5 7.6e-05 22.9 2.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KII94994.1 - 6.4e-11 42.2 19.2 3.8e-06 27.1 0.5 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KII94994.1 - 3.2e-07 30.6 18.0 0.0021 18.7 1.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 KII94994.1 - 0.032 14.6 2.2 14 6.2 0.6 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII94994.1 - 0.041 14.2 1.7 5.2 7.5 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KII94994.1 - 0.14 12.5 2.1 1.1 9.6 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 KII94994.1 - 0.18 11.8 5.0 9.2 6.4 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KII94994.1 - 0.23 11.8 6.7 3.4 8.0 1.6 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KII94994.1 - 6.2 6.7 9.6 1.7 8.5 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type UCH PF00443.29 KII94995.1 - 7.4e-50 169.8 0.0 9.9e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KII94995.1 - 1e-21 77.9 0.0 4.2e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KII94995.1 - 0.011 15.2 0.4 1.1 8.7 1.2 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 KII94995.1 - 0.23 11.5 1.4 1.7 8.7 0.0 2.5 2 1 0 2 2 2 0 Double zinc ribbon PP2C PF00481.21 KII94996.1 - 5.4e-27 95.0 0.0 2e-25 89.9 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C ACT_7 PF13840.6 KII94998.1 - 9.9e-19 66.9 0.0 3.6e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 KII94998.1 - 0.056 13.3 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 KII94998.1 - 0.15 11.8 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 ACT domain Cation_ATPase_C PF00689.21 KII94999.1 - 0.12 12.1 6.3 0.14 11.8 6.3 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DNA_mis_repair PF01119.19 KII95000.1 - 4.4e-15 55.4 0.0 1.1e-13 50.8 0.0 2.6 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KII95000.1 - 2.2e-07 30.8 0.0 4.3e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KII95000.1 - 3.8e-05 24.1 0.0 8.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KII95000.1 - 0.0015 18.3 0.0 0.022 14.6 0.0 2.8 3 1 0 3 3 3 1 MutL C terminal dimerisation domain SSXRD PF09514.10 KII95000.1 - 0.048 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 SSXRD motif Carboxyl_trans PF01039.22 KII95001.1 - 3.6e-133 444.8 0.2 4.4e-133 444.5 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KII95001.1 - 0.0016 18.0 0.2 0.081 12.4 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ArfGap PF01412.18 KII95002.1 - 2.9e-33 114.4 0.0 5.1e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-piccolo PF05715.13 KII95002.1 - 0.067 13.3 0.7 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Velvet PF11754.8 KII95003.1 - 9.2e-83 278.0 6.4 5.7e-81 272.1 6.4 2.1 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.6 KII95004.1 - 1e-33 115.3 7.5 1.7e-07 31.3 0.0 10.2 10 1 1 12 12 12 5 PPR repeat family PPR_3 PF13812.6 KII95004.1 - 2.7e-29 101.0 0.0 1.5e-09 37.8 0.1 7.2 6 1 3 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.20 KII95004.1 - 6.6e-29 98.1 6.6 0.087 13.1 0.0 13.9 15 0 0 15 15 15 8 PPR repeat PPR_long PF17177.4 KII95004.1 - 2.7e-14 53.0 1.0 0.00068 19.1 0.0 4.6 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KII95004.1 - 7.2e-13 48.0 6.6 0.039 13.7 0.1 10.2 12 0 0 12 12 12 2 PPR repeat TPR_14 PF13428.6 KII95004.1 - 1.7e-06 28.4 15.2 2.4 9.2 0.0 8.8 6 4 4 11 11 11 3 Tetratricopeptide repeat GATase_6 PF13522.6 KII95004.1 - 0.00044 20.4 0.0 0.0038 17.4 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain TPR_16 PF13432.6 KII95004.1 - 0.025 15.2 9.2 10 6.9 0.0 5.3 6 2 0 6 6 6 0 Tetratricopeptide repeat DUF2597 PF10772.9 KII95004.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) GATase_7 PF13537.6 KII95004.1 - 0.1 12.5 0.0 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain Acetyltransf_10 PF13673.7 KII95005.1 - 7.7e-13 48.5 0.0 9.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KII95005.1 - 5.9e-06 26.9 0.2 0.00031 21.4 0.0 2.7 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KII95005.1 - 6.3e-05 23.3 0.0 9.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII95005.1 - 0.00014 22.0 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HMG_box PF00505.19 KII95006.1 - 7.9e-14 51.8 14.9 2.1e-06 28.0 3.7 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KII95006.1 - 7.1e-12 45.8 10.4 8.8e-06 26.2 4.2 2.7 2 1 0 2 2 2 2 HMG-box domain GRIM-19 PF06212.12 KII95007.1 - 3.4e-28 98.2 0.0 4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein CLIP_SPH_mas PF18398.1 KII95010.1 - 0.085 13.3 3.2 1.1 9.7 0.3 2.6 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade Fer4 PF00037.27 KII95011.1 - 6.7e-14 51.0 17.5 2e-08 33.7 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KII95011.1 - 4.4e-13 49.6 10.4 7.6e-13 48.8 10.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KII95011.1 - 5.5e-10 40.0 10.5 2.1e-05 25.3 1.0 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KII95011.1 - 1.8e-09 37.6 21.4 1e-06 28.8 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KII95011.1 - 2e-09 37.5 6.4 0.00024 21.2 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KII95011.1 - 2.3e-08 34.3 4.5 0.00019 21.8 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KII95011.1 - 2.5e-08 34.0 10.8 4.5e-08 33.1 10.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KII95011.1 - 5.2e-07 29.5 17.8 0.00045 20.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KII95011.1 - 1.4e-06 28.0 11.7 0.0026 17.7 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KII95011.1 - 5.2e-06 26.6 10.4 0.0003 21.1 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KII95011.1 - 0.00014 22.3 12.7 0.014 16.0 11.7 2.7 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KII95011.1 - 0.00049 20.6 9.9 0.1 13.1 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 KII95011.1 - 0.014 15.6 5.8 0.41 10.9 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KII95011.1 - 0.053 13.7 9.2 1.2 9.3 1.4 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KII95011.1 - 0.27 12.1 11.6 2.3 9.1 1.6 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KII95011.1 - 0.28 12.2 16.3 0.4 11.7 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KII95011.1 - 0.66 10.1 7.0 3.1 8.0 0.9 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 KII95011.1 - 0.75 9.8 6.3 0.42 10.7 0.6 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins Prefoldin_2 PF01920.20 KII95012.1 - 2.2e-21 75.8 0.1 2.8e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit APG6_N PF17675.1 KII95012.1 - 0.033 14.7 0.1 8.7 6.9 0.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 KII95012.1 - 0.058 13.0 0.8 5.1 6.7 0.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DASH_Dad3 PF08656.10 KII95012.1 - 0.071 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad3 CAP PF00188.26 KII95013.1 - 3.8e-19 69.8 3.1 4.9e-19 69.4 3.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SET PF00856.28 KII95014.1 - 2.7e-11 44.2 0.0 9.3e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 KII95014.1 - 1.6e-05 24.6 4.1 0.042 14.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KII95014.1 - 0.00017 22.1 7.0 0.004 17.8 4.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII95014.1 - 0.00025 21.6 2.6 0.62 11.0 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII95014.1 - 0.00051 19.7 0.2 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 KII95014.1 - 0.002 18.3 2.5 0.074 13.2 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII95014.1 - 0.013 15.3 0.1 0.085 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 KII95015.1 - 3.1e-07 30.2 2.2 1e-06 28.5 2.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII95015.1 - 0.0019 18.5 0.7 0.035 14.6 0.1 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.33 KII95015.1 - 0.079 12.9 0.7 2 8.4 0.0 3.2 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 KII95015.1 - 5.8 7.9 5.3 8.5 7.4 1.7 3.2 2 1 0 2 2 2 0 Leucine Rich Repeat RNF220 PF15926.5 KII95016.1 - 1.1e-15 58.0 12.9 1.6e-08 34.5 2.5 2.7 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KII95016.1 - 9.5e-09 35.0 14.8 9.5e-09 35.0 14.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII95016.1 - 1.6e-05 24.6 23.2 0.00015 21.6 11.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII95016.1 - 9.1e-05 22.3 14.5 9.1e-05 22.3 14.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII95016.1 - 0.00013 21.8 21.7 0.00014 21.7 12.8 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KII95016.1 - 0.00061 19.8 23.0 0.0016 18.4 8.0 4.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KII95016.1 - 0.00082 19.7 16.0 0.00082 19.7 16.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.6 KII95016.1 - 0.024 14.5 8.4 0.024 14.5 8.4 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-Di19 PF05605.12 KII95016.1 - 0.051 13.9 7.7 3.2 8.1 0.5 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KII95016.1 - 0.11 12.4 21.2 4.3 7.3 14.2 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KII95016.1 - 3.5 7.8 11.5 1.8 8.8 8.1 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KII95020.1 - 2.5e-09 36.8 14.8 3.5e-09 36.4 14.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 KII95020.1 - 4.3e-06 26.5 2.7 6.6e-06 25.9 0.7 2.0 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4 PF00097.25 KII95020.1 - 2.3e-05 24.2 14.5 3.3e-05 23.6 14.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII95020.1 - 3.6e-05 23.5 11.9 5.1e-05 23.1 11.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII95020.1 - 3.6e-05 23.6 12.8 5e-05 23.2 12.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII95020.1 - 0.00021 21.5 16.0 0.0003 21.1 16.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KII95020.1 - 0.00077 19.4 8.2 0.00077 19.4 8.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KII95020.1 - 0.0038 17.1 8.2 0.0068 16.2 8.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KII95020.1 - 0.015 15.1 6.1 0.024 14.4 6.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KII95020.1 - 0.035 14.0 12.7 1.6 8.6 14.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SepRS_C PF18006.1 KII95020.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain zf-RING_10 PF16685.5 KII95020.1 - 0.4 10.8 8.1 0.59 10.3 8.1 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KII95020.1 - 0.54 10.5 12.0 1.9 8.7 12.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_transf_8C PF08437.10 KII95022.1 - 0.064 13.3 0.1 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal PgpA PF04608.13 KII95022.1 - 1.7 8.7 8.4 20 5.2 0.0 3.9 5 0 0 5 5 5 0 Phosphatidylglycerophosphatase A RNF220 PF15926.5 KII95023.1 - 6.8e-14 52.1 14.0 8.9e-08 32.1 2.9 2.7 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KII95023.1 - 1.1e-08 34.8 14.8 1.1e-08 34.8 14.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII95023.1 - 4.5e-06 26.4 22.3 0.00016 21.4 11.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII95023.1 - 3.5e-05 23.7 20.1 0.00015 21.6 12.8 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII95023.1 - 0.0001 22.1 14.5 0.0001 22.1 14.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII95023.1 - 0.00091 19.5 16.0 0.00091 19.5 16.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KII95023.1 - 0.00091 19.2 23.3 0.0018 18.3 8.0 4.3 4 0 0 4 4 4 1 RING-type zinc-finger zf-Di19 PF05605.12 KII95023.1 - 0.0034 17.6 9.4 0.97 9.8 1.0 4.2 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_6 PF14835.6 KII95023.1 - 0.027 14.4 8.4 0.027 14.4 8.4 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF4685 PF15737.5 KII95023.1 - 0.036 14.5 0.4 0.058 13.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) zf-WRNIP1_ubi PF18279.1 KII95023.1 - 0.56 11.0 6.7 31 5.5 0.5 3.7 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Prok-RING_4 PF14447.6 KII95023.1 - 1.5 8.8 23.5 4.3 7.3 14.0 4.0 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KII95023.1 - 3.9 7.4 16.4 0.11 12.4 6.8 2.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KII95023.1 - 6.4 7.0 11.9 2 8.6 8.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 PAS_7 PF12860.7 KII95028.1 - 0.11 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 PAS fold RNF220 PF15926.5 KII95031.1 - 1.1e-14 54.7 13.4 1.3e-07 31.6 2.8 2.8 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KII95031.1 - 1e-08 34.8 14.8 1e-08 34.8 14.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII95031.1 - 5.1e-06 26.3 22.5 0.00016 21.5 11.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KII95031.1 - 3e-05 23.9 20.0 0.00015 21.6 12.8 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KII95031.1 - 9.9e-05 22.1 14.5 9.9e-05 22.1 14.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII95031.1 - 0.00089 19.5 16.0 0.00089 19.5 16.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KII95031.1 - 0.00095 19.2 23.3 0.0017 18.3 8.0 4.2 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_6 PF14835.6 KII95031.1 - 0.026 14.4 8.4 0.026 14.4 8.4 2.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-Di19 PF05605.12 KII95031.1 - 0.029 14.6 8.9 0.95 9.8 1.0 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KII95031.1 - 0.33 10.9 21.8 4 7.4 14.0 4.0 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-WRNIP1_ubi PF18279.1 KII95031.1 - 0.57 10.9 6.7 31 5.5 0.5 3.7 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Nse PF11789.8 KII95031.1 - 4.6 7.1 16.5 0.077 12.8 6.1 2.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 KII95031.1 - 6 7.1 11.8 2 8.6 8.0 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 Tom7 PF08038.12 KII95032.1 - 1e-20 73.1 0.3 1.1e-20 72.9 0.3 1.0 1 0 0 1 1 1 1 TOM7 family JAB PF01398.21 KII95033.1 - 2.2e-23 82.5 0.1 1.7e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KII95033.1 - 9e-19 68.0 0.0 1.5e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KII95033.1 - 0.0043 17.1 0.2 0.0072 16.4 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) UreF PF01730.16 KII95034.1 - 1.4e-26 93.6 0.3 1.9e-26 93.2 0.3 1.1 1 0 0 1 1 1 1 UreF AFG1_ATPase PF03969.16 KII95035.1 - 1.2e-97 327.1 0.0 7.9e-94 314.5 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KII95035.1 - 0.00032 21.1 0.6 0.039 14.3 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KII95035.1 - 0.0024 18.3 0.0 0.0063 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII95035.1 - 0.0034 17.7 0.0 0.0092 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 KII95035.1 - 0.034 14.0 0.1 0.25 11.2 0.0 2.1 2 1 0 2 2 2 0 Bacterial dnaA protein TniB PF05621.11 KII95035.1 - 0.057 12.8 0.1 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein TsaE PF02367.17 KII95035.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KII95035.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region SBDS PF01172.18 KII95036.1 - 1.9e-18 66.3 0.0 2.4e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein LTD PF00932.19 KII95036.1 - 0.094 13.1 0.2 1.8 8.9 0.0 2.5 1 1 2 3 3 3 0 Lamin Tail Domain F-box-like PF12937.7 KII95037.1 - 9.5e-05 22.2 3.4 0.00039 20.2 3.4 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KII95038.1 - 3.8e-07 29.9 0.5 9.8e-07 28.6 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII95038.1 - 0.0069 16.8 0.1 0.026 14.9 0.1 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Y_phosphatase3 PF13350.6 KII95039.1 - 4.3e-60 203.6 0.0 4.9e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KII95039.1 - 0.028 14.0 0.0 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family Glyco_transf_7C PF02709.14 KII95039.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase MCM PF00493.23 KII95040.1 - 1.6e-103 344.6 0.3 2.4e-103 344.1 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KII95040.1 - 9.1e-38 128.9 0.0 1.7e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KII95040.1 - 7.8e-30 103.3 0.7 1.7e-29 102.2 0.7 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KII95040.1 - 2.8e-25 88.5 1.1 5.9e-25 87.5 1.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KII95040.1 - 3.3e-25 88.7 0.4 8.7e-25 87.3 0.4 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KII95040.1 - 1.2e-07 31.4 0.0 1.3e-06 27.9 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KII95040.1 - 0.0018 18.1 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KII95040.1 - 0.0025 17.5 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KII95040.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_3_C PF01915.22 KII95041.1 - 2.2e-61 207.4 0.0 2.7e-60 203.8 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KII95041.1 - 4.1e-48 164.4 0.0 7.4e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KII95041.1 - 7.1e-26 90.1 0.2 1.5e-25 89.1 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KII95041.1 - 6.4e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Vac14_Fig4_bd PF11916.8 KII95042.1 - 1e-79 266.4 6.4 1.7e-79 265.6 6.4 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KII95042.1 - 3.2e-39 133.4 0.1 8.1e-37 125.7 0.0 3.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KII95042.1 - 4.7e-10 38.9 2.0 0.014 15.6 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KII95042.1 - 3.1e-06 27.5 0.7 3.3 8.3 0.0 6.1 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.7 KII95042.1 - 7.3e-06 26.1 0.7 0.85 9.6 0.0 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KII95042.1 - 1.2e-05 25.6 0.3 3.2 8.2 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats DUF3437 PF11919.8 KII95042.1 - 0.067 13.1 0.1 1.9 8.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) MMS19_C PF12460.8 KII95042.1 - 0.17 11.0 5.7 1.4 7.9 0.0 3.4 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal FH2 PF02181.23 KII95043.1 - 1.7e-86 290.7 2.3 5.6e-86 289.0 0.0 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KII95043.1 - 1.1e-26 93.6 7.6 5.2e-23 81.6 0.0 3.0 4 0 0 4 4 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KII95043.1 - 1e-21 77.5 0.2 3.1e-21 75.9 0.2 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain APG6_N PF17675.1 KII95043.1 - 0.0069 16.9 1.9 0.0069 16.9 1.9 4.0 2 1 0 2 2 2 1 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 KII95043.1 - 0.012 15.5 3.2 0.7 9.8 0.0 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Nmad5 PF18757.1 KII95043.1 - 0.027 14.7 3.5 2.2 8.4 3.0 2.8 2 1 0 2 2 2 0 Nucleotide modification associated domain 5 Snapin_Pallidin PF14712.6 KII95043.1 - 0.043 14.2 5.0 0.17 12.3 0.9 4.0 3 1 1 4 4 3 0 Snapin/Pallidin Tup_N PF08581.10 KII95043.1 - 0.12 12.7 8.0 0.16 12.3 0.2 4.0 3 1 1 4 4 4 0 Tup N-terminal DUF2576 PF10845.8 KII95043.1 - 0.15 11.7 0.3 37 4.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) Syntaxin_2 PF14523.6 KII95043.1 - 0.26 11.7 6.3 0.17 12.3 2.9 2.6 2 0 0 2 2 1 0 Syntaxin-like protein DUF812 PF05667.11 KII95043.1 - 0.27 10.1 18.4 0.14 11.0 15.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 KII95043.1 - 0.27 11.5 24.3 0.54 10.5 6.2 4.7 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain APC_N_CC PF16689.5 KII95043.1 - 0.99 9.5 5.2 12 6.1 2.5 3.0 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain JIP_LZII PF16471.5 KII95043.1 - 1.1 9.5 4.9 1.6 8.9 2.3 2.7 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 KII95043.1 - 2.6 8.3 23.0 3.4 7.9 7.8 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 KII95043.1 - 2.6 7.3 16.6 0.62 9.4 8.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KII95043.1 - 2.6 6.8 7.1 4.8 6.0 7.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Csm1_N PF18504.1 KII95043.1 - 2.7 8.4 19.3 2.8 8.3 0.1 4.9 4 0 0 4 4 4 0 Csm1 N-terminal domain IU_nuc_hydro PF01156.19 KII95044.1 - 2.2e-86 290.2 0.0 2.6e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RRN3 PF05327.11 KII95045.1 - 4.1e-206 685.8 0.0 4.1e-206 685.8 0.0 1.8 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 KII95045.1 - 0.00035 20.3 6.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 2 Grap2 and cyclin-D-interacting Complex1_LYR PF05347.15 KII95046.1 - 8.5e-10 38.5 0.3 1.3e-09 38.0 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) LNS2 PF08235.13 KII95047.1 - 4.8e-100 333.7 0.0 7e-100 333.1 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KII95047.1 - 3.3e-35 120.1 0.0 8.8e-35 118.8 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KII95047.1 - 4e-06 26.9 0.0 9.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 KII95047.1 - 0.055 13.1 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DRMBL PF07522.14 KII95048.1 - 5.6e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KII95048.1 - 0.0036 16.9 2.0 0.048 13.2 2.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TBX PF12598.8 KII95048.1 - 0.19 12.6 0.1 0.19 12.6 0.1 3.4 3 0 0 3 3 3 0 T-box transcription factor tRNA_synthFbeta PF17759.1 KII95049.1 - 6.9e-51 172.7 0.0 1.3e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KII95049.1 - 1.1e-31 108.9 0.2 1e-30 105.7 0.0 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KII95049.1 - 1.4e-25 90.0 0.0 2.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KII95049.1 - 2.5e-18 66.1 0.0 9e-16 57.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KII95049.1 - 0.0051 16.3 0.0 0.046 13.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Diphthami_syn_2 PF01902.17 KII95050.1 - 3.4e-37 128.1 0.0 2.2e-29 102.5 0.0 2.2 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KII95050.1 - 5.3e-10 39.4 0.0 6.7e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Endoribonuclease L-PSP MFS_2 PF13347.6 KII95051.1 - 2.8e-06 26.2 4.0 2.8e-06 26.2 4.0 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Reticulon PF02453.17 KII95051.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.5 4 0 0 4 4 4 0 Reticulon TMEM192 PF14802.6 KII95051.1 - 9.2 5.3 5.7 1.3 8.0 0.1 2.2 2 1 0 2 2 2 0 TMEM192 family Ank_4 PF13637.6 KII95052.1 - 6.3e-22 77.7 2.9 8.6e-12 45.3 0.1 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KII95052.1 - 8.1e-21 74.4 0.0 1.6e-13 51.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KII95052.1 - 1.7e-15 56.9 1.0 1e-07 32.1 0.2 3.9 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII95052.1 - 2.7e-12 45.7 0.4 0.00019 21.6 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KII95052.1 - 1.2e-10 41.4 1.4 0.0011 19.3 0.2 4.1 4 0 0 4 4 4 2 Ankyrin repeat FYRN PF05964.14 KII95053.1 - 0.034 14.0 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus Wtap PF17098.5 KII95054.1 - 2.4e-17 63.3 3.7 2.8e-16 59.8 3.7 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family PKcGMP_CC PF16808.5 KII95054.1 - 0.02 14.7 2.3 7.4 6.5 0.0 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_DNA_bd PF12329.8 KII95054.1 - 0.11 12.5 1.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40_alt PF14077.6 KII95054.1 - 0.14 12.1 0.9 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif SlyX PF04102.12 KII95054.1 - 0.34 11.5 6.2 6.5 7.5 0.6 3.3 2 1 0 2 2 2 0 SlyX Glyco_hydro_18 PF00704.28 KII95055.1 - 1.1e-50 173.2 0.0 1.2e-50 173.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COesterase PF00135.28 KII95056.1 - 1.3e-96 324.5 0.0 1.5e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII95056.1 - 9.4e-08 32.2 0.2 4.1e-07 30.1 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold eRF1_1 PF03463.15 KII95057.1 - 1.8e-47 160.6 0.0 2.8e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KII95057.1 - 6.5e-23 81.4 0.0 1.2e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KII95057.1 - 2.6e-17 63.4 0.0 4.2e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Glyco_trans_4_2 PF13477.6 KII95057.1 - 0.072 13.1 0.1 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like Thioredoxin PF00085.20 KII95058.1 - 0.0068 16.4 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KII95058.1 - 0.0083 15.1 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Phosducin PMT2_N PF17987.1 KII95058.1 - 0.019 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal FAD_binding_7 PF03441.14 KII95059.1 - 8.2e-79 263.8 0.5 1.4e-78 263.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KII95059.1 - 1.7e-33 115.9 0.1 3.1e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase T6PP_N PF18572.1 KII95059.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain adh_short PF00106.25 KII95060.1 - 2.9e-27 95.4 0.1 3.9e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95060.1 - 3.6e-19 69.3 0.1 4.6e-19 68.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95060.1 - 4.7e-06 26.6 0.0 6.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII95060.1 - 3.4e-05 23.4 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 KII95060.1 - 0.0055 16.7 0.1 0.018 15.0 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.6 KII95060.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KII95060.1 - 0.017 14.6 0.0 0.079 12.3 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 KII95061.1 - 0.00011 22.0 0.0 0.00054 19.8 0.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII95061.1 - 0.4 11.2 3.9 2.2 8.9 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF5127 PF17168.4 KII95062.1 - 2.8e-83 279.2 10.0 5.1e-83 278.3 10.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KII95062.1 - 7e-75 250.5 1.9 7.5e-75 250.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KII95062.1 - 2e-67 226.8 2.4 2e-67 226.8 2.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KII95062.1 - 7.1e-09 35.1 2.4 1.2e-08 34.4 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 KII95062.1 - 0.0018 17.9 0.9 0.005 16.4 0.9 1.7 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Glyco_hydro_28 PF00295.17 KII95065.1 - 4.5e-63 213.3 18.5 6.6e-63 212.7 18.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KII95065.1 - 7.3e-08 32.4 14.1 7.3e-08 32.4 14.1 2.3 2 1 0 2 2 2 1 Right handed beta helix region OMPdecase PF00215.24 KII95066.1 - 1.4e-70 237.4 0.0 1.8e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.18 KII95067.1 - 8.3e-78 262.0 0.0 1.4e-73 248.1 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) GRP PF07172.11 KII95067.1 - 2 9.1 12.9 4.1 8.2 4.6 2.6 2 0 0 2 2 2 0 Glycine rich protein family FoP_duplication PF13865.6 KII95067.1 - 7.2 7.2 34.2 14 6.3 16.8 3.8 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 KII95068.1 - 5.4e-32 111.1 23.5 2.8e-30 105.4 18.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII95068.1 - 3.2e-06 26.3 11.9 3.2e-06 26.3 11.9 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KII95068.1 - 0.0087 15.0 1.2 0.0087 15.0 1.2 2.0 2 1 1 3 3 3 1 Sugar-tranasporters, 12 TM DUF1129 PF06570.11 KII95068.1 - 3.7 7.0 7.0 1.8 8.0 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Gly_transf_sug PF04488.15 KII95069.1 - 8.5e-23 80.8 0.2 1.5e-22 80.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KII95069.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain PIN_4 PF13638.6 KII95070.1 - 2.4e-19 69.9 0.0 3.9e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 KII95070.1 - 0.039 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 PIN like domain SelP_N PF04592.14 KII95070.1 - 0.14 11.6 0.3 0.28 10.6 0.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CTD_bind PF04818.13 KII95071.1 - 0.00067 20.4 0.0 0.0014 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 KII95071.1 - 0.049 14.1 0.1 0.23 12.0 0.0 2.1 2 1 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Ribosomal_L6 PF00347.23 KII95072.1 - 1.4e-29 102.5 3.1 2.8e-16 60.0 1.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 CBM_4_9 PF02018.17 KII95072.1 - 0.016 15.4 0.0 0.03 14.6 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate binding domain ICMT PF04140.14 KII95073.1 - 2e-26 92.2 1.1 2e-26 92.2 1.1 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KII95073.1 - 3.6e-12 46.6 1.5 3.6e-12 46.6 1.5 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KII95073.1 - 5.3e-05 22.8 0.8 5.3e-05 22.8 0.8 1.9 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.12 KII95073.1 - 0.00074 19.1 1.2 0.0013 18.2 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GTP_EFTU PF00009.27 KII95074.1 - 6e-50 169.5 0.0 9.3e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KII95074.1 - 4.1e-13 49.2 0.0 5.3e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 KII95074.1 - 2.1e-12 47.0 0.0 4.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KII95074.1 - 4.2e-05 23.8 0.1 0.00012 22.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII95074.1 - 0.0005 20.1 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 KII95074.1 - 0.2 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain DTHCT PF08070.11 KII95075.1 - 1.2 9.9 10.9 0.43 11.4 7.7 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region ADH_N PF08240.12 KII95079.1 - 7.5e-31 106.2 0.6 1.2e-30 105.6 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII95079.1 - 9.7e-23 80.6 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KII95079.1 - 1.2e-07 32.8 0.1 4.1e-07 31.1 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII95079.1 - 0.0011 18.5 0.3 0.66 9.4 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 KII95079.1 - 0.0023 18.6 0.0 0.0043 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 KII95079.1 - 0.0076 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KII95079.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 KII95079.1 - 0.065 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KII95079.1 - 0.12 13.0 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KII95079.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_lectin_2 PF18647.1 KII95080.1 - 0.0054 17.2 0.5 0.0086 16.5 0.3 1.4 1 1 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin MFS_1 PF07690.16 KII95081.1 - 2e-20 73.0 65.4 2.9e-19 69.2 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KII95081.1 - 0.00045 19.6 20.0 0.0017 17.7 20.0 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 KII95082.1 - 3.7e-51 174.0 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95082.1 - 9.3e-31 107.0 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII95082.1 - 2.7e-05 23.6 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KII95082.1 - 0.0023 17.9 0.1 0.029 14.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KII95082.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Meth_synt_2 PF01717.18 KII95083.1 - 6.2e-148 492.4 0.0 2e-144 480.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KII95083.1 - 4.5e-118 394.3 0.0 9.4e-112 373.6 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 KII95083.1 - 0.078 12.9 1.5 4 7.4 0.2 2.7 2 0 0 2 2 2 0 Antitoxin VbhA Phage_XkdX PF09693.10 KII95083.1 - 0.2 11.7 2.2 1.2 9.2 0.3 3.0 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) PMSR PF01625.21 KII95084.1 - 1.8e-58 197.1 0.4 2.2e-58 196.8 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2985 PF11204.8 KII95087.1 - 1.2e-27 95.8 1.3 2.3e-27 95.0 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Apt1 PF10351.9 KII95088.1 - 6.1e-90 302.4 0.2 6.1e-90 302.4 0.2 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KII95088.1 - 7.6e-60 203.1 0.0 6.6e-59 200.0 0.0 2.2 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 KII95088.1 - 1e-36 126.4 0.0 2e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KII95088.1 - 5.7e-21 75.1 0.0 1.4e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KII95088.1 - 2.6e-17 63.4 0.0 1.3e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DNA_pol_E_B PF04042.16 KII95089.1 - 3.9e-46 157.1 0.4 6.5e-46 156.3 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KII95089.1 - 0.0018 18.3 0.1 0.0042 17.2 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain BET PF17035.5 KII95089.1 - 1.2 9.4 4.9 5.5 7.2 0.8 2.7 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation UPF0183 PF03676.14 KII95090.1 - 1.9e-60 205.3 0.0 2.5e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Hydrolase PF00702.26 KII95091.1 - 5.2e-07 30.2 0.0 3e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KII95091.1 - 1.7e-06 28.3 0.0 3.8e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KII95091.1 - 0.00025 21.1 0.0 0.00067 19.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KII95091.1 - 0.00053 19.6 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2608) PNK3P PF08645.11 KII95091.1 - 0.027 14.1 0.0 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Ribosomal_L6e PF01159.19 KII95092.1 - 1.6e-38 131.6 0.1 2.5e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 KII95092.1 - 6.2e-07 29.6 2.7 8.6e-07 29.1 0.1 2.5 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain TonB_2 PF13103.6 KII95092.1 - 0.012 15.8 0.1 0.035 14.4 0.1 1.9 1 1 1 2 2 2 0 TonB C terminal TonB_C PF03544.14 KII95092.1 - 0.21 12.0 1.7 4.3 7.9 0.0 2.6 3 0 0 3 3 3 0 Gram-negative bacterial TonB protein C-terminal 60KD_IMP PF02096.20 KII95093.1 - 1.1e-13 51.4 0.0 4e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein DUF4381 PF14316.6 KII95093.1 - 3 8.1 8.1 0.47 10.7 0.8 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Clat_adaptor_s PF01217.20 KII95094.1 - 2.9e-56 189.4 1.2 3.4e-56 189.1 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EloA-BP1 PF15870.5 KII95095.1 - 1.2e-05 25.7 0.3 2.4e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 RNase_T PF00929.24 KII95095.1 - 0.0024 18.4 0.0 0.0061 17.1 0.0 1.8 2 1 0 2 2 2 1 Exonuclease CHORD PF04968.12 KII95095.1 - 0.0071 17.0 3.9 0.015 16.0 3.9 1.5 1 0 0 1 1 1 1 CHORD TRAM_LAG1_CLN8 PF03798.16 KII95096.1 - 3.6e-33 115.0 23.8 6.5e-33 114.1 23.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KII95096.1 - 1.1e-18 66.6 0.4 1.1e-18 66.6 0.4 2.4 3 0 0 3 3 3 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 KII95097.1 - 1.2e-29 103.5 25.8 1.2e-29 103.5 25.8 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KII95097.1 - 5.1e-17 61.3 0.4 1.9e-16 59.5 0.3 2.1 2 0 0 2 2 2 1 TRAM1-like protein Histone PF00125.24 KII95099.1 - 7.4e-43 146.1 0.4 8.3e-43 145.9 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KII95099.1 - 0.00056 20.0 0.1 0.0009 19.3 0.1 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KII95099.1 - 0.0012 19.2 0.1 0.0017 18.7 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KII95099.1 - 0.014 15.6 0.8 0.025 14.9 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone adh_short PF00106.25 KII95100.1 - 1.2e-19 70.6 0.0 5.5e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95100.1 - 2.3e-10 40.4 0.0 1.3e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95100.1 - 0.00022 21.2 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KII95100.1 - 0.0033 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 KII95100.1 - 0.078 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CENP-B_dimeris PF09026.10 KII95101.1 - 0.61 10.5 5.1 1.6 9.2 5.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain OB_RNB PF08206.11 KII95102.1 - 0.09 12.5 0.6 0.11 12.2 0.6 1.2 1 0 0 1 1 1 0 Ribonuclease B OB domain Nop14 PF04147.12 KII95103.1 - 0.017 13.4 1.2 0.026 12.8 1.2 1.2 1 0 0 1 1 1 0 Nop14-like family zf-RRN7 PF11781.8 KII95103.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Upf2 PF04050.14 KII95103.1 - 0.1 13.3 2.7 0.2 12.4 1.6 2.0 1 1 1 2 2 2 0 Up-frameshift suppressor 2 DnaJ PF00226.31 KII95104.1 - 6.4e-17 61.4 0.0 1.1e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 KII95104.1 - 0.082 13.5 3.8 0.66 10.6 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Gln-synt_C PF00120.24 KII95105.1 - 9.2e-17 61.1 0.0 1.4e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KII95105.1 - 1.4e-12 47.2 0.0 2.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SLS PF14611.6 KII95105.1 - 0.27 11.1 0.1 0.49 10.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator HrpB1_HrpK PF09613.10 KII95106.1 - 0.078 12.6 0.4 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Iso_dh PF00180.20 KII95107.1 - 2.9e-78 263.5 0.0 3.5e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Chlorophyllase2 PF12740.7 KII95108.1 - 0.15 10.9 0.0 0.84 8.5 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Methyltransf_33 PF10017.9 KII95109.1 - 3.2e-39 134.9 0.0 3.6e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_33 PF10017.9 KII95111.1 - 4.7e-34 117.9 0.0 5.9e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent NikR_C PF08753.11 KII95111.1 - 0.16 12.1 0.8 0.36 11.0 0.3 1.8 2 0 0 2 2 2 0 NikR C terminal nickel binding domain Sugar_tr PF00083.24 KII95112.1 - 1.4e-20 73.6 26.1 5.6e-12 45.3 8.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KII95112.1 - 1.3e-13 50.7 33.0 1.3e-13 50.7 33.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-MYND PF01753.18 KII95113.1 - 1.5e-10 41.0 9.7 2.7e-10 40.2 9.7 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 KII95114.1 - 0.046 13.6 3.1 0.064 13.2 0.4 2.3 2 0 0 2 2 2 0 F-box-like Amidohydro_2 PF04909.14 KII95115.1 - 3.6e-28 99.2 0.3 4.4e-28 98.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.25 KII95116.1 - 8.5e-39 133.0 0.1 1.1e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95116.1 - 4.1e-32 111.6 0.1 4.8e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95116.1 - 1.6e-13 51.0 0.2 3.4e-13 49.9 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KII95116.1 - 0.0014 18.1 0.1 0.033 13.7 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KII95116.1 - 0.0016 18.4 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 KII95116.1 - 0.056 13.2 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.13 KII95116.1 - 0.094 12.2 0.4 0.19 11.3 0.4 1.4 2 0 0 2 2 2 0 NmrA-like family Transket_pyr PF02779.24 KII95117.1 - 7e-48 162.7 0.0 1.4e-47 161.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KII95117.1 - 4.4e-42 142.9 0.1 8.3e-42 142.0 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KII95117.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Histidinol_dh PF00815.20 KII95118.1 - 1e-164 548.4 1.6 1.3e-164 548.0 1.6 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KII95118.1 - 5e-24 83.9 0.3 1e-23 82.9 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KII95118.1 - 6e-11 42.6 0.3 4.2e-10 39.9 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 KII95118.1 - 0.036 14.2 0.5 0.036 14.2 0.5 1.7 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain AIRC PF00731.20 KII95118.1 - 0.044 13.4 0.1 1.9 8.1 0.2 2.6 2 0 0 2 2 2 0 AIR carboxylase Val_tRNA-synt_C PF10458.9 KII95119.1 - 0.021 15.1 0.5 0.038 14.3 0.5 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm TspO_MBR PF03073.15 KII95120.1 - 3.1e-40 137.3 8.8 3.7e-40 137.1 8.8 1.0 1 0 0 1 1 1 1 TspO/MBR family Glyco_hydro_16 PF00722.21 KII95121.1 - 5.2e-07 29.3 0.1 9.9e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Piwi PF02171.17 KII95122.1 - 9.5e-91 304.2 0.0 1.4e-90 303.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KII95122.1 - 4.4e-25 88.9 0.0 8.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KII95122.1 - 1.4e-15 56.6 0.1 3.7e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KII95122.1 - 2.2e-14 53.4 0.0 5.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 KII95122.1 - 1e-11 45.0 0.0 2.3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KII95122.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.27 KII95124.1 - 3.5e-61 203.1 3.0 2.5e-21 75.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 KII95124.1 - 0.0013 18.5 0.1 0.0097 15.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KII95124.1 - 0.003 17.0 1.7 0.016 14.7 0.1 2.9 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.6 KII95124.1 - 0.049 13.1 0.5 0.17 11.4 0.2 2.1 2 0 0 2 2 2 0 EF hand Pkinase_Tyr PF07714.17 KII95126.1 - 7.6e-36 123.7 0.0 8.1e-35 120.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KII95126.1 - 1e-33 116.8 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KII95126.1 - 1.7e-05 24.3 0.0 4.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KII95126.1 - 0.00096 18.0 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KII95126.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KII95126.1 - 0.056 12.8 0.2 0.091 12.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPR_2 PF13041.6 KII95127.1 - 0.059 13.6 0.8 7.8 6.8 0.0 2.5 2 1 0 2 2 2 0 PPR repeat family SNARE_assoc PF09335.11 KII95128.1 - 5e-16 59.3 3.5 5e-16 59.3 3.5 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_L36e PF01158.18 KII95130.1 - 1.1e-39 134.6 3.8 1.2e-39 134.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 KII95130.1 - 0.076 13.1 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CK_II_beta PF01214.18 KII95131.1 - 1.4e-73 246.6 0.0 1.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.13 KII95131.1 - 6.7e-05 23.1 2.9 6.7e-05 23.1 2.9 1.8 2 0 0 2 2 2 1 YL1 nuclear protein SWIRM-assoc_2 PF16496.5 KII95131.1 - 0.054 12.4 4.0 0.057 12.3 2.7 1.6 1 1 0 1 1 1 0 SWIRM-associated domain at the N-terminal SLAIN PF15301.6 KII95131.1 - 0.81 8.9 10.8 0.069 12.4 5.5 1.8 2 0 0 2 2 2 0 SLAIN motif-containing family SDA1 PF05285.12 KII95131.1 - 3.2 7.1 11.5 0.075 12.4 4.0 1.8 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 KII95131.1 - 3.3 6.9 12.9 0.35 10.2 8.1 1.7 2 0 0 2 2 2 0 BUD22 CRCB PF02537.15 KII95132.1 - 1.4e-31 108.6 14.3 1.3e-18 67.1 4.0 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Rab5ip PF07019.12 KII95132.1 - 0.0075 16.8 2.3 0.0075 16.8 2.3 2.9 4 0 0 4 4 4 1 Rab5-interacting protein (Rab5ip) Med17 PF10156.9 KII95133.1 - 5.3e-45 154.0 0.0 6.6e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PepX_C PF08530.10 KII95133.1 - 0.0015 18.5 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Fungal_trans PF04082.18 KII95134.1 - 1.8e-18 66.5 0.0 2.8e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII95134.1 - 4.7e-05 23.4 10.1 7.2e-05 22.8 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.9 KII95135.1 - 1.4e-12 48.2 1.1 1.8e-12 47.8 1.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Snf7 PF03357.21 KII95136.1 - 3.5e-29 101.6 20.3 3.5e-29 101.6 20.3 1.5 1 1 0 1 1 1 1 Snf7 LUC7 PF03194.15 KII95136.1 - 0.014 15.1 3.6 0.014 15.1 3.6 2.1 1 1 1 2 2 2 0 LUC7 N_terminus E2F_CC-MB PF16421.5 KII95136.1 - 1.1 9.7 6.7 0.12 12.7 0.6 2.4 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain Iso_dh PF00180.20 KII95137.1 - 4.3e-101 338.5 0.0 5.4e-101 338.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.19 KII95138.1 - 1.4e-100 336.8 0.0 2.6e-100 335.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KII95138.1 - 6.1e-26 90.6 0.2 1.5e-25 89.3 0.2 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KII95138.1 - 1.8e-24 85.5 0.0 3.9e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KII95138.1 - 0.00026 21.1 0.0 0.1 12.8 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 KII95138.1 - 0.0011 18.9 0.0 0.0039 17.1 0.0 2.0 1 1 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KII95138.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain BTB_2 PF02214.22 KII95139.1 - 0.12 12.7 0.0 0.69 10.3 0.0 2.3 1 1 0 1 1 1 0 BTB/POZ domain Rpr2 PF04032.16 KII95140.1 - 0.00029 21.1 0.2 0.00062 20.0 0.2 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RTA1 PF04479.13 KII95141.1 - 8.4e-55 185.6 5.8 1.1e-54 185.1 5.8 1.2 1 0 0 1 1 1 1 RTA1 like protein VID27 PF08553.10 KII95143.1 - 1.1e-173 577.3 0.9 1.5e-173 576.9 0.9 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KII95143.1 - 3.7e-58 196.2 0.1 3.7e-58 196.2 0.1 2.7 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 KII95143.1 - 2e-29 102.1 2.4 4.8e-29 100.8 2.4 1.7 1 0 0 1 1 1 1 VID27 PH-like domain adh_short PF00106.25 KII95145.1 - 1.4e-28 99.7 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95145.1 - 3.3e-15 56.3 0.0 4.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95145.1 - 3.9e-08 33.4 0.2 6e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KII95145.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KII95145.1 - 0.0057 16.1 0.0 0.019 14.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 KII95145.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.16 KII95145.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 KII95145.1 - 0.19 11.6 0.7 0.52 10.2 0.7 1.9 1 1 0 1 1 1 0 NAD(P)H-binding AAA_16 PF13191.6 KII95146.1 - 5.8e-11 43.1 0.3 2.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KII95146.1 - 5.3e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KII95146.1 - 6e-05 23.3 0.0 1.8 8.9 0.0 5.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 KII95146.1 - 0.0029 18.0 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII95146.1 - 0.0038 17.5 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PQQ_2 PF13360.6 KII95146.1 - 0.005 16.5 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 1 1 PQQ-like domain MeaB PF03308.16 KII95146.1 - 0.012 14.6 0.1 0.049 12.6 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PD40 PF07676.12 KII95146.1 - 0.014 15.3 6.0 71 3.5 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KII95146.1 - 0.014 16.2 14.8 1.2 10.1 0.0 6.9 7 1 1 8 8 6 0 WD domain, G-beta repeat DUF919 PF06034.11 KII95146.1 - 0.028 14.2 0.3 0.48 10.3 0.3 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Ge1_WD40 PF16529.5 KII95146.1 - 0.079 11.9 0.0 0.23 10.4 0.0 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KII95146.1 - 0.083 12.6 8.3 1.2 8.9 0.4 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3158 PF11358.8 KII95146.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Zeta_toxin PF06414.12 KII95146.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KII95146.1 - 0.15 12.6 0.1 0.84 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KII95146.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ribosomal_L5e PF17144.4 KII95147.1 - 2e-81 271.8 0.1 3.4e-81 271.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KII95147.1 - 3.2e-34 117.7 2.7 3.2e-34 117.7 2.7 2.2 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region MtrA PF04208.14 KII95147.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A RRM_1 PF00076.22 KII95148.1 - 3.2e-15 55.7 0.0 4.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WH2 PF02205.20 KII95149.1 - 3.9e-06 26.5 2.8 1.3e-05 24.8 1.7 2.4 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.20 KII95150.1 - 1.3e-57 192.1 0.0 6e-31 106.5 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KII95150.1 - 3.2e-41 141.3 0.0 2.2e-32 112.4 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KII95150.1 - 3.6e-08 33.8 0.7 0.0025 18.2 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KII95150.1 - 6.6e-08 32.6 0.2 0.015 15.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 KII95150.1 - 8.7e-06 25.0 0.0 6.3e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 KII95150.1 - 1.6e-05 25.2 0.2 0.17 12.2 0.0 3.8 4 1 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 KII95150.1 - 0.0001 22.2 0.2 0.43 10.5 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 KII95150.1 - 0.004 16.6 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 KII95150.1 - 0.03 14.0 1.1 11 5.7 0.0 3.2 4 0 0 4 4 4 0 Redoxin Glutaredoxin PF00462.24 KII95150.1 - 0.049 13.9 2.1 2.4 8.4 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin SLATT_5 PF18160.1 KII95151.1 - 3 7.1 6.7 0.44 9.8 1.6 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF485 PF04341.12 KII95151.1 - 3.5 7.6 8.2 0.081 12.9 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF485 TCTP PF00838.17 KII95152.1 - 4.4e-76 254.8 1.1 4.9e-76 254.7 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RcbX PF02341.15 KII95152.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 RbcX protein UTP15_C PF09384.10 KII95153.1 - 1.3e-50 170.9 0.0 2e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KII95153.1 - 3.2e-21 75.2 2.9 0.00029 21.6 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95153.1 - 1e-08 35.4 0.0 0.021 15.1 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KII95153.1 - 0.0056 15.3 0.1 0.027 13.0 0.0 2.0 2 1 0 2 2 2 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 KII95153.1 - 0.0092 15.1 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region CTNNBL PF08216.11 KII95154.1 - 1.3e-33 115.3 0.0 3.5e-33 113.9 0.0 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Spore_III_AB PF09548.10 KII95154.1 - 0.046 13.8 0.5 0.12 12.5 0.3 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1685 PF07939.11 KII95156.1 - 1.5 8.6 4.2 26 4.6 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1685) PCI PF01399.27 KII95157.1 - 1.3e-10 41.7 0.0 4.1e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KII95157.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TAFH PF07531.14 KII95157.1 - 0.06 13.4 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 NHR1 homology to TAF Cohesin_load PF10345.9 KII95157.1 - 0.096 11.1 0.1 0.14 10.5 0.1 1.2 1 0 0 1 1 1 0 Cohesin loading factor CHZ PF09649.10 KII95158.1 - 0.11 12.0 3.8 0.18 11.3 3.8 1.3 1 0 0 1 1 1 0 Histone chaperone domain CHZ Pkinase PF00069.25 KII95159.1 - 1.6e-78 263.7 0.0 1.9e-78 263.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95159.1 - 2.1e-38 132.1 0.0 2.9e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII95159.1 - 5.9e-07 29.1 0.0 1e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KII95159.1 - 0.00013 21.0 0.1 0.0015 17.6 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KII95159.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KII95159.1 - 0.0061 15.9 0.4 0.014 14.7 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HAS-barrel PF09378.10 KII95159.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 HAS barrel domain WD40 PF00400.32 KII95160.1 - 1.1e-14 54.6 8.2 8.4e-08 32.8 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95160.1 - 0.00089 19.5 0.1 0.027 14.8 0.0 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2179 PF10035.9 KII95160.1 - 0.083 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Asp PF00026.23 KII95161.1 - 5.2e-109 364.5 0.4 6.1e-109 364.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII95161.1 - 2e-15 57.5 2.3 1.2e-13 51.6 2.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KII95161.1 - 7.9e-06 26.4 0.1 0.057 14.1 0.0 3.5 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 KII95161.1 - 1.1e-05 25.3 0.0 0.00013 21.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KII95161.1 - 0.0011 19.5 0.0 0.8 10.3 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 KII95162.1 - 2.9e-23 81.7 0.1 6e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 KII95162.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain HsbA PF12296.8 KII95162.1 - 0.027 14.9 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A FAT PF02259.23 KII95163.1 - 7.2e-67 226.1 7.6 1.7e-66 224.8 7.6 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KII95163.1 - 3e-21 76.4 0.0 5.9e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase HEAT PF02985.22 KII95163.1 - 0.0086 16.3 0.2 6.6 7.3 0.1 4.1 3 0 0 3 3 3 1 HEAT repeat FATC PF02260.20 KII95163.1 - 0.023 14.5 0.3 0.15 11.9 0.1 2.5 2 0 0 2 2 2 0 FATC domain PUB PF09409.10 KII95164.1 - 3.5e-10 39.7 0.0 6.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain EF_assoc_1 PF08355.12 KII95164.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 EF hand associated DUF3759 PF12585.8 KII95165.1 - 7.5e-37 125.2 10.9 8.8e-37 125.0 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF5558 PF17713.1 KII95166.1 - 0.35 11.2 5.7 0.87 10.0 4.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5558) DUF3336 PF11815.8 KII95167.1 - 1.9e-49 166.9 1.1 2.9e-49 166.3 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KII95167.1 - 8.2e-20 71.9 0.1 1.8e-19 70.7 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase BCDHK_Adom3 PF10436.9 KII95169.1 - 1.5e-42 145.2 0.0 2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KII95169.1 - 6.5e-09 36.3 0.0 1.2e-07 32.2 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KII95169.1 - 0.00042 20.1 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med20 PF08612.11 KII95170.1 - 3.5e-09 36.4 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.6 KII95171.1 - 4.6e-30 104.6 0.0 8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KII95171.1 - 4.9e-20 72.6 0.0 9.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KII95171.1 - 0.00066 20.1 0.0 0.0039 17.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KII95171.1 - 0.0079 16.1 0.1 0.093 12.6 0.1 2.2 1 1 0 1 1 1 1 NACHT domain RNA12 PF10443.9 KII95171.1 - 0.011 14.5 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein AAA_22 PF13401.6 KII95171.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KII95171.1 - 0.035 14.3 0.0 0.18 12.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KII95171.1 - 0.039 13.9 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KII95171.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 KII95171.1 - 0.19 11.8 0.0 0.65 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain LON_substr_bdg PF02190.16 KII95172.1 - 4.5e-21 75.7 0.0 6.6e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KII95172.1 - 4.5e-13 48.8 28.6 4.2e-11 42.5 13.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KII95172.1 - 6.2e-10 39.1 26.2 4.6e-05 23.5 11.1 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KII95172.1 - 9.9e-10 38.3 25.9 2.3e-07 30.7 8.6 3.0 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII95172.1 - 1.5e-09 37.6 23.3 3.6e-08 33.1 7.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KII95172.1 - 5.2e-09 35.8 26.7 5.9e-07 29.3 12.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII95172.1 - 5e-07 30.0 12.6 5e-07 30.0 12.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KII95172.1 - 1.4e-06 28.2 27.6 1.9e-06 27.7 11.2 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KII95172.1 - 3.5e-06 26.8 9.3 3.5e-06 26.8 9.3 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KII95172.1 - 2e-05 24.6 4.4 2e-05 24.6 4.4 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KII95172.1 - 0.0014 18.5 15.3 0.034 14.0 3.1 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KII95172.1 - 0.012 15.4 6.3 0.012 15.4 6.3 3.1 2 2 1 3 3 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KII95172.1 - 0.022 15.1 10.5 0.022 15.1 10.5 2.7 2 2 0 2 2 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KII95172.1 - 0.17 12.0 2.6 0.59 10.2 2.6 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 KII95172.1 - 1.2 8.9 14.4 0.038 13.7 6.9 2.3 2 0 0 2 2 2 0 P-11 zinc finger Polysacc_deac_1 PF01522.21 KII95173.1 - 9.3e-21 74.0 0.0 2.5e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF1682 PF07946.14 KII95175.1 - 6.3e-91 304.9 0.0 7.6e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) SCFA_trans PF02667.14 KII95175.1 - 0.82 8.6 1.7 4.9 6.0 0.2 2.0 2 0 0 2 2 2 0 Short chain fatty acid transporter NdhN PF11909.8 KII95176.1 - 0.033 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N BRX_N PF13713.6 KII95176.1 - 0.11 12.3 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF3818 PF12825.7 KII95177.1 - 8.3e-136 452.5 0.3 1.2e-135 451.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KII95177.1 - 4.3e-34 117.3 0.3 1.2e-33 115.9 0.3 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KII95177.1 - 5.8e-11 42.4 0.1 2.7e-10 40.2 0.1 2.2 1 0 0 1 1 1 1 PX domain DEAD PF00270.29 KII95178.1 - 1.8e-40 138.5 0.0 4.4e-40 137.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KII95178.1 - 1.4e-24 86.1 0.3 2.7e-24 85.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KII95178.1 - 4.5e-20 72.0 0.0 1.9e-19 70.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII95178.1 - 5.5e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RPN2_C PF18004.1 KII95178.1 - 3.6 7.5 13.1 9.8 6.1 11.9 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain TT_ORF2 PF02957.15 KII95178.1 - 5.6 7.9 9.5 12 6.8 9.3 1.7 1 1 0 1 1 1 0 TT viral ORF2 Lectin_N PF03954.14 KII95179.1 - 0.13 12.1 2.1 0.29 10.9 1.2 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain UPF0184 PF03670.13 KII95179.1 - 0.23 11.9 6.2 25 5.4 4.1 3.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) DUF1826 PF08856.11 KII95179.1 - 2.7 7.9 7.8 0.17 11.8 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1826) DUF4407 PF14362.6 KII95179.1 - 5 6.4 39.1 1.7 8.0 9.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Ribosomal_L7Ae PF01248.26 KII95180.1 - 2.9e-25 87.8 2.2 6.3e-25 86.7 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EMI PF07546.13 KII95180.1 - 0.07 13.9 0.8 0.14 12.9 0.8 1.5 1 0 0 1 1 1 0 EMI domain DUF1979 PF09322.10 KII95181.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Cupin_8 PF13621.6 KII95182.1 - 3.4e-60 203.9 0.0 5.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KII95182.1 - 0.0022 17.6 0.3 0.04 13.6 0.1 2.4 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 KII95182.1 - 0.0048 17.3 0.1 0.032 14.7 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KII95182.1 - 0.11 12.0 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Cupin superfamily protein AAA PF00004.29 KII95183.1 - 3.9e-06 27.3 0.7 3.7e-05 24.2 0.7 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KII95183.1 - 0.00015 21.8 0.3 0.004 17.1 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KII95183.1 - 0.0017 18.8 0.0 0.038 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KII95183.1 - 0.032 14.2 0.0 0.084 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KII95183.1 - 0.089 12.4 0.1 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KII95183.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KII95183.1 - 0.23 10.6 0.2 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HLH PF00010.26 KII95184.1 - 6.7e-13 48.4 0.2 1.3e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 KII95185.1 - 7.2e-65 219.0 0.0 1.5e-43 149.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII95185.1 - 1.4e-28 99.9 0.0 2.1e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KII95185.1 - 4.8e-07 29.0 0.0 6.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KII95185.1 - 0.00035 20.0 0.1 0.001 18.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII95185.1 - 0.00057 19.9 0.2 0.018 15.0 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KII95185.1 - 0.0015 17.9 0.1 0.0077 15.6 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KII95185.1 - 0.035 12.9 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KII95185.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KII95185.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 KII95185.1 - 0.055 14.2 0.3 0.12 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 KII95185.1 - 0.077 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TCL1_MTCP1 PF01840.17 KII95186.1 - 0.035 13.8 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 TCL1/MTCP1 family Aconitase PF00330.20 KII95187.1 - 1.9e-09 37.1 3.3 4.7e-08 32.5 0.7 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) F-box-like PF12937.7 KII95188.1 - 0.088 12.7 0.5 0.19 11.6 0.5 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 KII95189.1 - 0.0078 16.1 0.3 0.016 15.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like DUF4649 PF15507.6 KII95189.1 - 0.15 12.1 0.0 0.84 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4649) LRR_2 PF07723.13 KII95189.1 - 0.19 12.4 0.7 2.3 9.0 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich Repeat UQ_con PF00179.26 KII95190.1 - 1.3e-38 131.8 0.1 1.6e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KII95190.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 UEV domain FmiP_Thoc5 PF09766.9 KII95191.1 - 8e-39 134.0 16.3 9.7e-39 133.7 16.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 T3SSipB PF16535.5 KII95191.1 - 0.0071 16.8 9.4 0.047 14.2 3.9 2.2 2 0 0 2 2 2 1 Type III cell invasion protein SipB Syntaxin PF00804.25 KII95191.1 - 0.029 14.0 7.4 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Syntaxin GCIP PF13324.6 KII95191.1 - 0.034 13.8 4.2 0.059 13.0 3.9 1.7 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF948 PF06103.11 KII95191.1 - 0.098 12.9 1.7 3.2 8.1 0.8 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 KII95191.1 - 0.11 12.5 6.7 0.37 10.8 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CREPT PF16566.5 KII95191.1 - 0.14 12.3 11.0 0.09 12.9 5.3 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Mod_r PF07200.13 KII95191.1 - 0.27 11.3 14.2 0.33 11.0 8.9 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.9 KII95191.1 - 0.37 10.8 14.7 1.1 9.3 8.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GCN5L1 PF06320.13 KII95191.1 - 0.87 9.7 10.0 1.1 9.5 2.2 2.5 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) G2BR PF18442.1 KII95191.1 - 1.4 8.6 7.9 2.9 7.6 2.1 2.8 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) YabA PF06156.13 KII95191.1 - 4.7 7.9 9.4 5.1 7.8 2.5 2.5 2 1 0 2 2 2 0 Initiation control protein YabA G6PD_C PF02781.16 KII95192.1 - 1.1e-111 372.7 0.0 1.6e-111 372.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KII95192.1 - 3.2e-60 203.8 0.0 5.1e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MRP_L53 PF10780.9 KII95192.1 - 0.068 13.4 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Pou PF00157.17 KII95193.1 - 0.027 14.4 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain F-box-like PF12937.7 KII95194.1 - 0.0007 19.4 0.2 0.0014 18.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF1218 PF06749.12 KII95195.1 - 0.25 11.9 4.5 1.3 9.6 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) OppC_N PF12911.7 KII95195.1 - 2.2 8.3 6.4 9.7 6.3 0.0 3.0 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ferlin_C PF16165.5 KII95196.1 - 1 9.3 4.3 14 5.6 0.8 2.1 2 0 0 2 2 2 0 Ferlin C-terminus PMP22_Claudin PF00822.20 KII95197.1 - 0.4 10.5 7.2 0.11 12.3 4.2 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family AMP-binding PF00501.28 KII95198.1 - 6.4e-38 130.5 0.0 9.7e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KII95198.1 - 2.5e-06 27.3 1.0 4.9e-06 26.4 1.0 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KII95198.1 - 0.00012 23.0 0.1 0.00024 22.0 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3759 PF12585.8 KII95199.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) Metallophos PF00149.28 KII95200.1 - 2.9e-06 27.9 0.5 4.9e-06 27.2 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RFX_DNA_binding PF02257.15 KII95201.1 - 6e-28 97.3 0.0 1.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain NuDC PF16273.5 KII95201.1 - 0.1 13.1 0.4 0.21 12.1 0.4 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain PPR_2 PF13041.6 KII95203.1 - 1.1e-17 63.9 0.7 2.7e-11 43.5 0.0 5.4 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 KII95203.1 - 8.3e-10 38.2 2.1 0.057 13.7 0.0 6.8 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 KII95203.1 - 2.2e-06 27.3 0.0 0.44 10.3 0.1 4.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KII95203.1 - 0.00043 20.3 0.0 0.038 14.1 0.0 3.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KII95203.1 - 0.039 13.3 0.0 3.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP Asp PF00026.23 KII95204.1 - 1.6e-34 119.8 0.1 3.6e-33 115.3 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII95204.1 - 1.7e-06 28.4 1.0 0.0043 17.3 0.1 3.4 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Shisa PF13908.6 KII95204.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Fe-ADH PF00465.19 KII95205.1 - 1.1e-91 307.4 0.0 1.5e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KII95205.1 - 2.6e-11 43.7 0.1 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.21 KII95206.1 - 4.6e-37 127.7 0.0 5.9e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.23 KII95207.1 - 7.9e-19 67.4 0.7 7.9e-19 67.4 0.7 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 KII95207.1 - 0.053 13.6 0.3 0.19 11.9 0.3 1.9 1 1 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pkinase PF00069.25 KII95208.1 - 3.7e-70 236.3 0.0 5.2e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95208.1 - 1.1e-46 159.3 0.0 1.5e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KII95208.1 - 0.00081 18.3 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KII95208.1 - 0.002 17.5 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.11 KII95208.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Polysacc_deac_1 PF01522.21 KII95210.1 - 7e-25 87.3 0.0 2.3e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 KII95212.1 - 1.8e-19 69.9 0.1 1.4e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF4043 PF13252.6 KII95212.1 - 0.057 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) TFIIF_alpha PF05793.12 KII95213.1 - 3.1e-12 45.9 52.0 6.4e-06 25.1 1.9 3.9 3 1 0 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EF-1_beta_acid PF10587.9 KII95213.1 - 0.013 15.9 1.4 0.013 15.9 1.4 5.6 5 1 0 5 5 5 0 Eukaryotic elongation factor 1 beta central acidic region Ribophorin_I PF04597.14 KII95215.1 - 1.2e-137 459.7 0.5 1.5e-137 459.4 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L22 PF00237.19 KII95216.1 - 9.7e-23 80.4 0.2 1.7e-22 79.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GILT PF03227.16 KII95217.1 - 2e-17 63.4 0.4 2e-17 63.4 0.4 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Yos1 PF08571.10 KII95218.1 - 3.6e-29 100.9 0.1 4.4e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Yos1-like Cid2 PF09774.9 KII95219.1 - 1.7e-26 93.6 5.0 2e-25 90.1 5.0 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Asp PF00026.23 KII95220.1 - 8.3e-48 163.4 9.3 3.3e-47 161.5 9.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII95220.1 - 4.9e-08 33.4 5.9 0.00013 22.2 0.2 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Aminotran_1_2 PF00155.21 KII95221.1 - 4.3e-63 213.7 0.0 4.9e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII95221.1 - 2.6e-05 23.0 0.0 5.6e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KII95221.1 - 0.004 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KII95221.1 - 0.0057 15.7 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KII95221.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sec63 PF02889.16 KII95222.1 - 4.5e-72 242.3 0.0 6.4e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KII95222.1 - 6.3e-34 117.3 0.5 1.2e-25 90.3 0.2 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KII95222.1 - 8.8e-14 51.9 0.0 3.9e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KII95222.1 - 9.8e-07 29.1 0.0 0.00042 20.6 0.0 3.5 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KII95222.1 - 5.4e-06 26.7 0.4 0.021 15.1 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KII95222.1 - 0.002 18.5 0.2 0.013 15.8 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KII95222.1 - 0.0041 16.9 0.0 0.016 14.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 KII95222.1 - 0.034 14.3 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal helicase PWI domain Glyco_transf_4 PF13439.6 KII95222.1 - 0.11 12.5 0.2 7.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Glycosyltransferase Family 4 DUF4897 PF16238.5 KII95222.1 - 0.12 12.2 0.2 5.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) AAA_11 PF13086.6 KII95222.1 - 0.16 11.7 0.1 0.55 10.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 KII95223.1 - 2.2e-113 379.5 20.8 2.7e-113 379.2 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII95223.1 - 7.4e-24 84.3 40.8 1.8e-19 69.9 11.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KII95223.1 - 0.1 12.8 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) F-box-like PF12937.7 KII95224.1 - 1.9e-05 24.4 0.1 0.0001 22.1 0.1 2.3 1 1 0 1 1 1 1 F-box-like ATE_C PF04377.15 KII95226.1 - 6.5e-48 162.7 0.6 1e-47 162.1 0.6 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KII95226.1 - 2.1e-27 95.3 5.4 3.5e-27 94.6 5.4 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KII95226.1 - 0.13 12.4 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S24 PF00717.23 KII95227.1 - 4.8e-11 42.5 0.1 9.2e-11 41.5 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KII95227.1 - 0.012 15.5 0.1 4.9 6.9 0.1 2.8 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 WD40 PF00400.32 KII95228.1 - 0.0016 19.2 0.0 0.096 13.6 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95228.1 - 0.0033 17.7 0.0 1.7 9.0 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF839 PF05787.13 KII95228.1 - 0.025 13.7 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DUF1513 PF07433.11 KII95228.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Osteoregulin PF07175.11 KII95229.1 - 0.045 14.0 0.1 0.048 13.9 0.1 1.1 1 0 0 1 1 1 0 Osteoregulin EF-hand_7 PF13499.6 KII95231.1 - 1.7e-26 92.5 7.2 1.5e-17 63.8 1.7 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KII95231.1 - 3.3e-24 82.6 12.5 3.5e-08 32.4 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KII95231.1 - 4.9e-21 72.8 8.9 1.6e-06 27.5 0.1 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 KII95231.1 - 1.1e-12 47.6 11.7 5.6e-06 26.1 0.7 3.8 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 KII95231.1 - 1.3e-12 46.6 9.3 0.00077 18.8 0.4 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 KII95231.1 - 7.5e-07 29.1 6.3 0.084 12.8 0.2 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KII95231.1 - 0.00011 22.5 3.5 0.14 12.5 0.6 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KII95231.1 - 0.0037 17.6 3.1 2.2 8.7 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain Pan3_PK PF18101.1 KII95231.1 - 0.035 14.1 0.2 0.066 13.2 0.2 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Caleosin PF05042.13 KII95231.1 - 0.042 13.8 2.3 9.3 6.1 0.0 3.2 2 1 0 3 3 3 0 Caleosin related protein DUF1298 PF06974.13 KII95231.1 - 0.21 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) EMC3_TMCO1 PF01956.16 KII95232.1 - 9.8e-51 171.9 0.0 1.4e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like V-SNARE PF05008.15 KII95233.1 - 2.6e-22 79.0 10.3 2.7e-22 78.9 5.0 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KII95233.1 - 2.6e-15 56.4 5.4 2.6e-15 56.4 5.4 2.8 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 KII95233.1 - 0.0033 17.4 1.2 0.009 16.0 1.2 1.8 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.13 KII95233.1 - 0.044 13.7 0.5 0.044 13.7 0.5 2.0 2 1 0 2 2 2 0 Sec20 RIFIN PF02009.16 KII95233.1 - 0.052 13.4 0.6 0.068 13.1 0.4 1.4 1 1 0 1 1 1 0 Rifin Exonuc_VII_L PF02601.15 KII95233.1 - 0.098 12.2 10.1 0.61 9.6 10.1 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit YqjK PF13997.6 KII95233.1 - 0.13 12.5 0.7 0.29 11.4 0.2 2.0 2 0 0 2 2 2 0 YqjK-like protein RmuC PF02646.16 KII95233.1 - 0.14 11.3 8.1 0.54 9.3 0.4 2.2 2 0 0 2 2 2 0 RmuC family APG6_N PF17675.1 KII95233.1 - 0.49 10.9 10.0 0.069 13.7 1.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Prominin PF05478.11 KII95233.1 - 0.87 7.5 5.3 5.3 4.9 5.3 1.9 1 1 0 1 1 1 0 Prominin Spore_III_AB PF09548.10 KII95233.1 - 1.1 9.3 7.0 0.45 10.6 0.4 2.6 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Fib_alpha PF08702.10 KII95233.1 - 3.3 7.9 9.3 16 5.6 1.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family KCH PF16944.5 KII95234.1 - 1.9e-88 296.5 16.3 2.3e-88 296.2 16.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3917 PF13055.6 KII95234.1 - 0.02 15.3 1.6 0.029 14.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) DUF2593 PF10767.9 KII95234.1 - 4.3 7.4 7.9 1.2 9.2 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2593) MMR_HSR1_Xtn PF16897.5 KII95235.1 - 1.7e-39 134.1 0.4 5.7e-39 132.4 0.2 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KII95235.1 - 1.6e-24 85.7 0.1 3e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KII95235.1 - 6.1e-21 74.6 0.0 1.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KII95235.1 - 5.6e-09 35.7 0.2 1.2e-08 34.6 0.1 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KII95235.1 - 0.01 14.8 0.3 0.031 13.3 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KII95235.1 - 0.028 14.5 0.6 7.8 6.5 0.4 2.5 1 1 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KII95235.1 - 0.39 10.6 1.5 1.8 8.4 0.6 2.3 2 1 0 2 2 2 0 RsgA GTPase Alg6_Alg8 PF03155.15 KII95236.1 - 1.7e-164 548.4 27.1 2e-164 548.2 27.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VMA21 PF09446.10 KII95237.1 - 5.1e-12 45.7 8.1 7.3e-12 45.2 8.1 1.2 1 0 0 1 1 1 1 VMA21-like domain SLATT_5 PF18160.1 KII95237.1 - 4.2 6.6 6.8 4.9 6.4 6.8 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 SbcCD_C PF13558.6 KII95239.1 - 0.019 15.2 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DPBB_1 PF03330.18 KII95240.1 - 5.5e-07 29.8 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase WD40 PF00400.32 KII95241.1 - 1.9e-49 164.5 22.4 2.3e-07 31.4 0.1 12.5 12 1 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95241.1 - 7.9e-21 74.2 5.9 1.6e-05 25.1 0.0 9.1 4 3 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KII95241.1 - 1.5e-18 67.1 0.8 2.7e-18 66.2 0.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KII95241.1 - 1.4e-07 30.6 3.8 0.043 12.5 0.0 4.9 4 1 0 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 KII95241.1 - 6.6e-07 28.9 0.0 0.51 9.6 0.1 4.2 4 1 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KII95241.1 - 6.8e-07 28.6 6.7 0.019 13.9 0.1 5.9 3 3 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KII95241.1 - 0.059 12.3 3.7 3.3 6.5 0.0 4.2 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain RAB3GAP2_N PF14655.6 KII95241.1 - 0.066 12.5 0.3 3.2 6.9 0.0 3.0 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 KII95241.1 - 0.19 10.4 8.3 4.3 6.0 0.2 5.0 2 2 3 5 5 5 0 Nup133 N terminal like Peptidase_M18 PF02127.15 KII95242.1 - 1.7e-160 534.5 0.0 2e-160 534.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KII95242.1 - 0.0018 17.3 0.5 0.18 10.8 0.3 2.4 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase Brix PF04427.18 KII95243.1 - 3.8e-31 108.7 0.9 5.3e-31 108.2 0.9 1.2 1 0 0 1 1 1 1 Brix domain Ribonuc_red_sm PF00268.21 KII95244.1 - 4.3e-122 406.9 1.5 5.3e-122 406.7 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KII95244.1 - 0.13 13.1 0.0 0.35 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Ribonuc_red_sm PF00268.21 KII95245.1 - 5.8e-120 399.9 0.1 7e-120 399.7 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MethyTransf_Reg PF10119.9 KII95245.1 - 0.081 13.6 0.0 0.87 10.4 0.0 2.7 3 0 0 3 3 3 0 Predicted methyltransferase regulatory domain Imm61 PF15598.6 KII95245.1 - 0.1 12.5 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 61 DUF4744 PF15918.5 KII95245.1 - 0.1 13.4 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Aldose_epim PF01263.20 KII95246.1 - 7.3e-58 196.2 0.8 9e-58 195.9 0.8 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase LPAM_1 PF08139.12 KII95246.1 - 0.048 14.2 5.5 0.087 13.3 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site TAFH PF07531.14 KII95247.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 NHR1 homology to TAF Vps52 PF04129.12 KII95248.1 - 1.9e-60 205.0 0.4 6e-42 144.0 0.0 2.9 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 KII95248.1 - 9.3e-06 24.3 0.0 0.00061 18.3 0.2 2.3 1 1 1 2 2 2 2 Exocyst complex component Sec3 bZIP_1 PF00170.21 KII95249.1 - 0.023 14.8 2.9 0.023 14.8 2.9 2.2 2 0 0 2 2 2 0 bZIP transcription factor Mitoc_mL59 PF18126.1 KII95249.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein mL59 Metal_resist PF13801.6 KII95249.1 - 0.4 10.9 4.5 1.5 9.0 3.9 2.3 1 1 1 2 2 2 0 Heavy-metal resistance JAB PF01398.21 KII95250.1 - 9.5e-33 112.7 0.2 1.6e-32 112.0 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KII95250.1 - 3.6e-14 53.1 0.9 6.8e-14 52.2 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KII95250.1 - 2.8e-06 27.1 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HXXSHH PF07586.11 KII95250.1 - 0.0023 17.6 0.1 0.0045 16.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) G6PD_bact PF10786.9 KII95250.1 - 0.042 13.4 0.3 0.062 12.8 0.3 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Ribosomal_S18 PF01084.20 KII95251.1 - 1.2e-15 57.5 0.1 2.1e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.25 KII95252.1 - 5.9e-62 209.4 0.0 8.2e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KII95252.1 - 7.2e-28 97.6 0.0 1.1e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KII95252.1 - 1.5e-12 47.7 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KII95252.1 - 7.1e-09 35.4 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KII95252.1 - 0.006 16.2 0.0 1.3 8.6 0.0 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KII95252.1 - 0.0062 16.5 0.2 0.0062 16.5 0.2 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KII95252.1 - 0.007 16.6 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 KII95252.1 - 0.0073 15.3 1.3 0.018 14.0 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KII95252.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII95252.1 - 0.041 13.5 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KII95252.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RRS1 PF04939.12 KII95254.1 - 7.1e-61 204.8 6.1 1.1e-60 204.2 6.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SAA PF00277.18 KII95254.1 - 7.4 7.1 8.0 0.3 11.6 1.1 2.1 2 1 0 2 2 2 0 Serum amyloid A protein TIP41 PF04176.13 KII95255.1 - 1.5e-62 210.1 0.0 1.8e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DLIC PF05783.11 KII95256.1 - 1.5e-42 146.1 5.8 7.1e-33 114.1 0.0 4.2 3 2 0 4 4 4 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KII95256.1 - 0.00091 19.6 0.2 0.0043 17.4 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KII95256.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 KII95256.1 - 0.045 14.0 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KII95256.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 KII95256.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KII95256.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KII95256.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KII95256.1 - 0.19 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KII95256.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Dynamin_N PF00350.23 KII95256.1 - 0.22 11.6 0.0 0.5 10.4 0.0 1.5 1 0 0 1 1 1 0 Dynamin family G-alpha PF00503.20 KII95256.1 - 0.32 10.1 0.1 0.5 9.5 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Pax7 PF12360.8 KII95257.1 - 0.039 14.1 4.4 0.085 13.1 4.4 1.5 1 0 0 1 1 1 0 Paired box protein 7 Hep_59 PF07052.11 KII95258.1 - 5.6e-30 104.2 1.6 5.6e-30 104.2 1.6 2.8 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Pro-kuma_activ PF09286.11 KII95259.1 - 6.7e-38 130.2 0.0 1.2e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KII95259.1 - 0.061 12.6 0.3 0.19 11.0 0.3 1.9 1 1 0 1 1 1 0 Subtilase family eIF3m_C_helix PF18005.1 KII95260.1 - 1.1e-13 50.6 1.3 2.6e-13 49.4 1.3 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KII95260.1 - 3.7e-11 43.5 0.0 1.5e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF2009 PF09418.10 KII95261.1 - 1.2e-211 703.7 0.0 1.4e-211 703.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KII95261.1 - 2.9e-05 24.1 6.9 5.1e-05 23.3 6.9 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KII95261.1 - 0.00028 21.0 7.7 0.0006 20.0 7.7 1.4 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain STIMATE PF12400.8 KII95262.1 - 2e-39 135.0 3.6 3.1e-39 134.4 3.6 1.3 1 0 0 1 1 1 1 STIMATE family MCPVI PF02993.14 KII95262.1 - 0.81 9.5 5.2 1.2 8.9 5.2 1.4 1 0 0 1 1 1 0 Minor capsid protein VI AAA PF00004.29 KII95264.1 - 4.7e-53 179.1 0.0 6.2e-39 133.4 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII95264.1 - 3.4e-11 43.6 0.2 2.5e-05 24.6 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 KII95264.1 - 2.2e-10 41.2 0.5 0.00077 19.9 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 KII95264.1 - 2.7e-08 33.5 0.2 1.1e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 KII95264.1 - 4.4e-08 32.8 0.1 9.9e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KII95264.1 - 1.6e-07 31.2 0.2 0.019 14.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KII95264.1 - 1.7e-07 31.6 0.1 6.2e-05 23.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KII95264.1 - 1.7e-07 31.3 0.6 0.0019 18.2 0.1 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KII95264.1 - 4.1e-07 30.2 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KII95264.1 - 4.7e-07 29.3 0.1 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 KII95264.1 - 1.9e-06 28.4 0.0 0.03 14.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KII95264.1 - 5.8e-06 25.8 0.2 0.0069 15.8 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KII95264.1 - 9.3e-06 25.7 0.1 0.067 13.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KII95264.1 - 2.4e-05 24.7 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 KII95264.1 - 2.6e-05 24.0 0.0 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KII95264.1 - 4.7e-05 23.4 1.4 0.2 11.6 0.0 3.2 3 1 0 3 3 3 2 NACHT domain AAA_11 PF13086.6 KII95264.1 - 9.1e-05 22.4 0.2 0.1 12.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KII95264.1 - 0.00012 21.8 0.1 0.22 11.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KII95264.1 - 0.00014 21.7 0.2 0.057 13.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KII95264.1 - 0.00015 21.2 1.4 0.024 14.0 0.1 2.6 2 1 0 2 2 2 1 KaiC CDC48_N PF02359.18 KII95264.1 - 0.00015 21.8 0.0 0.00096 19.3 0.0 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.26 KII95264.1 - 0.00023 20.9 0.1 0.62 9.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 KII95264.1 - 0.00075 19.4 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII95264.1 - 0.0011 18.2 0.1 0.46 9.6 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 KII95264.1 - 0.0014 18.2 1.7 0.081 12.4 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 KII95264.1 - 0.0018 18.8 0.3 0.14 12.7 0.1 2.4 2 0 0 2 2 2 1 ABC transporter ResIII PF04851.15 KII95264.1 - 0.0019 18.2 0.0 0.33 10.9 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KII95264.1 - 0.0026 18.0 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 KII95264.1 - 0.0032 16.6 0.1 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KII95264.1 - 0.0044 17.1 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KII95264.1 - 0.0046 16.5 2.6 3.6 7.1 0.0 3.6 2 2 0 4 4 4 1 AAA domain AAA_19 PF13245.6 KII95264.1 - 0.0048 17.2 0.8 1.3 9.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain Hydin_ADK PF17213.3 KII95264.1 - 0.0053 17.1 0.1 0.84 9.9 0.0 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 KII95264.1 - 0.0054 16.0 0.4 1.1 8.5 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KII95264.1 - 0.0063 16.4 0.1 50 3.7 0.1 4.0 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KII95264.1 - 0.013 15.9 0.2 2.6 8.5 0.1 3.0 3 0 0 3 3 2 0 AAA domain Torsin PF06309.11 KII95264.1 - 0.021 14.9 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Torsin T2SSE PF00437.20 KII95264.1 - 0.026 13.6 0.2 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 KII95264.1 - 0.026 14.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.12 KII95264.1 - 0.031 14.1 0.1 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KII95264.1 - 0.033 13.4 0.1 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 KII95264.1 - 0.079 12.4 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KII95264.1 - 0.1 12.5 0.2 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KII95264.1 - 0.11 12.2 0.1 19 4.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Viral_helicase1 PF01443.18 KII95264.1 - 0.16 11.7 0.0 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KII95264.1 - 0.17 11.5 0.2 19 4.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 KII95264.1 - 0.19 11.9 0.3 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase IPP-2 PF04979.14 KII95265.1 - 1.1e-16 61.7 6.4 3.5e-16 60.1 6.4 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF4337 PF14235.6 KII95265.1 - 8.7 6.4 6.3 15 5.6 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) THF_DHG_CYH PF00763.23 KII95266.1 - 2.6e-24 85.7 0.0 3.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KII95266.1 - 8.9e-16 57.6 0.1 2.9e-08 33.2 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ORMDL PF04061.14 KII95267.1 - 1.3e-53 180.5 2.8 1.8e-53 180.0 2.8 1.2 1 0 0 1 1 1 1 ORMDL family VIR_N PF15912.5 KII95268.1 - 4.3e-06 26.5 0.2 1.1e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 Virilizer, N-terminal Uds1 PF15456.6 KII95270.1 - 1.1e-33 116.1 11.2 1.1e-33 116.1 11.2 6.0 3 2 2 5 5 5 2 Up-regulated During Septation Taxilin PF09728.9 KII95270.1 - 0.0029 16.9 24.5 0.0029 16.9 24.5 4.8 4 1 1 5 5 5 1 Myosin-like coiled-coil protein DUF4200 PF13863.6 KII95270.1 - 0.0077 16.6 9.4 0.0077 16.6 9.4 6.8 4 3 2 6 6 6 1 Domain of unknown function (DUF4200) Tho1_MOS11_C PF18592.1 KII95270.1 - 3.7 7.4 8.9 0.37 10.6 1.1 3.4 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain FWWh PF14922.6 KII95271.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function SMK-1 PF04802.15 KII95273.1 - 1.7e-82 275.9 3.1 2.4e-82 275.4 1.1 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 TFIIB PF00382.19 KII95274.1 - 6.9e-35 118.9 0.0 8.5e-21 73.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KII95274.1 - 8.7e-14 50.8 1.6 1.4e-13 50.1 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 KII95274.1 - 0.0068 16.9 1.7 6.2 7.4 0.0 3.2 1 1 2 3 3 3 1 Guanylin precursor RB_B PF01857.20 KII95274.1 - 0.0072 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain HTH_5 PF01022.20 KII95274.1 - 0.032 14.1 0.1 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Cyclin_C PF02984.19 KII95274.1 - 0.038 14.1 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 KII95274.1 - 0.044 13.5 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HTH_Tnp_ISL3 PF13542.6 KII95274.1 - 0.13 11.7 0.0 13 5.3 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 KII95274.1 - 0.14 12.3 0.0 27 5.0 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain TetR_N PF00440.23 KII95274.1 - 0.16 11.8 0.6 1.7 8.5 0.5 2.7 3 1 0 3 3 3 0 Bacterial regulatory proteins, tetR family zf-ribbon_3 PF13248.6 KII95274.1 - 0.41 10.1 2.8 0.78 9.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_2 PF02230.16 KII95275.1 - 8.8e-58 195.7 0.0 2.5e-57 194.2 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KII95275.1 - 4e-05 24.3 1.1 5.7e-05 23.8 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KII95275.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KII95275.1 - 0.052 12.8 0.4 4.7 6.4 0.0 2.9 3 1 1 4 4 4 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KII95275.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA_m1G_MT PF01746.21 KII95276.1 - 1.4e-26 93.4 0.1 4.5e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Pex24p PF06398.11 KII95276.1 - 0.038 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin NARP1 PF12569.8 KII95276.1 - 1.5 7.7 7.2 3.1 6.6 7.2 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Methyltransf_23 PF13489.6 KII95277.1 - 1.7e-12 47.5 0.0 2.6e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII95277.1 - 3.2e-09 37.3 0.0 6.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII95277.1 - 3.4e-07 30.9 0.0 8.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII95277.1 - 3.5e-06 26.9 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII95277.1 - 9.6e-06 26.3 0.0 2.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KII95277.1 - 0.024 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FtsJ PF01728.19 KII95277.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase FOXP-CC PF16159.5 KII95278.1 - 0.12 13.0 7.6 2.2 9.0 0.5 3.7 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KII95278.1 - 5.1 8.2 11.0 2.2 9.4 0.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KII95278.1 - 5.3 7.7 5.3 8.4 7.1 1.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Glyco_hydro_7 PF00840.20 KII95279.1 - 0.052 12.3 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 RNA_pol_Rpb2_6 PF00562.28 KII95280.1 - 1.7e-111 373.1 0.0 3.3e-111 372.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KII95280.1 - 7.7e-36 123.5 0.0 1.4e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KII95280.1 - 1.3e-27 95.8 0.8 3.4e-27 94.4 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KII95280.1 - 1.2e-24 86.1 0.0 2.7e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KII95280.1 - 9.5e-22 77.6 0.0 1.8e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KII95280.1 - 8.3e-19 67.8 0.2 5.9e-15 55.5 0.2 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 UnbV_ASPIC PF07593.12 KII95280.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 ASPIC and UnbV Nucleoporin2 PF04096.14 KII95281.1 - 2.6e-44 150.9 0.0 4.1e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KII95281.1 - 1.9e-11 44.6 291.9 1.2e-06 29.3 21.3 11.2 3 2 7 10 10 10 6 Nucleoporin FG repeat region Ofd1_CTDD PF10637.9 KII95283.1 - 6.9e-75 251.7 0.1 9.2e-73 244.7 0.1 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KII95283.1 - 6.3e-30 103.7 0.0 1.6e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KII95283.1 - 1.4e-14 54.8 0.0 5.7e-14 52.8 0.0 2.1 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 KII95284.1 - 2.5e-19 68.8 0.0 1.4e-08 34.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KII95284.1 - 0.13 12.2 0.0 0.37 10.8 0.0 1.8 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nucleo_P87 PF07267.11 KII95284.1 - 0.64 8.8 8.7 1 8.1 8.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HIG_1_N PF04588.13 KII95288.1 - 0.0019 18.4 1.5 0.0037 17.4 1.5 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CLPTM1 PF05602.12 KII95289.1 - 1.8e-149 498.4 0.0 2.1e-149 498.2 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KII95289.1 - 0.00047 19.9 0.9 0.0013 18.4 0.3 2.1 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.6 KII95289.1 - 0.079 13.3 3.3 0.26 11.6 2.0 2.6 1 1 1 2 2 2 0 2TM domain TraC PF07820.12 KII95290.1 - 0.014 15.7 4.0 0.2 12.0 0.5 3.0 2 1 0 2 2 2 0 TraC-like protein Vsr PF03852.15 KII95290.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr MAS20 PF02064.15 KII95291.1 - 1.6e-38 131.7 0.3 6.2e-38 129.8 0.1 2.0 2 0 0 2 2 2 1 MAS20 protein import receptor SET PF00856.28 KII95291.1 - 7.6e-13 49.2 0.0 2.6e-12 47.5 0.0 1.9 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KII95291.1 - 0.005 17.4 0.1 6.9 7.4 0.0 2.7 2 0 0 2 2 2 2 SAF domain 14-3-3 PF00244.20 KII95292.1 - 3.3e-107 357.0 3.3 3.9e-107 356.8 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KII95292.1 - 0.29 11.6 2.2 0.72 10.4 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PGAP1 PF07819.13 KII95293.1 - 1.5e-54 185.2 0.0 2.1e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KII95293.1 - 8.3e-06 26.6 0.6 3.2e-05 24.6 0.6 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII95293.1 - 0.0026 17.4 0.0 0.014 15.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII95293.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KII95293.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CorA PF01544.18 KII95294.1 - 5.5e-46 157.2 0.3 9.9e-46 156.4 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KII95294.1 - 0.031 14.3 0.3 0.067 13.2 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 KII95295.1 - 6.7e-31 107.3 0.0 8.6e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KII95295.1 - 9e-21 74.5 0.0 6.8e-19 68.4 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95295.1 - 2.6e-09 37.2 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KII95295.1 - 5.8e-06 25.9 0.2 9.1e-06 25.3 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII95295.1 - 0.00033 20.2 0.1 0.0026 17.2 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KII95295.1 - 0.00064 20.0 0.2 0.0011 19.2 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_PK PF05891.12 KII95295.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Polysacc_synt_2 PF02719.15 KII95295.1 - 0.044 12.9 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KII95295.1 - 0.077 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.7 KII95296.1 - 2.8e-05 23.9 3.1 0.054 13.4 0.0 2.8 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 KII95296.1 - 0.072 13.0 0.2 5.7 6.9 0.1 2.5 2 0 0 2 2 2 0 F-box domain Atg14 PF10186.9 KII95297.1 - 0.092 11.8 4.0 0.17 10.9 4.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KII95297.1 - 0.62 8.9 14.7 1.2 8.0 14.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KII95297.1 - 1.2 7.0 3.7 1.9 6.3 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KII95297.1 - 1.7 7.9 10.8 0.39 10.0 7.4 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.9 KII95297.1 - 3.6 6.3 9.1 6 5.6 9.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 KII95297.1 - 3.7 8.0 12.1 0.94 9.9 5.5 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) OmpH PF03938.14 KII95297.1 - 5 7.5 7.7 2.9 8.2 4.5 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Amidohydro_2 PF04909.14 KII95298.1 - 1.4e-29 103.9 0.1 1.8e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Cyt-b5 PF00173.28 KII95300.1 - 3.8e-23 81.4 0.1 5.3e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OPT PF03169.15 KII95301.1 - 4.2e-132 441.9 47.7 4.8e-132 441.7 47.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Arginase PF00491.21 KII95302.1 - 2.9e-83 279.6 0.2 3.8e-83 279.2 0.2 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KII95302.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain PLU-1 PF08429.11 KII95303.1 - 3e-60 204.2 1.7 1.2e-59 202.2 1.1 2.3 2 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 KII95303.1 - 4.8e-41 139.8 1.2 2.6e-40 137.4 0.2 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.29 KII95303.1 - 2.6e-16 59.2 39.4 6.2e-11 42.0 10.5 4.8 4 0 0 4 4 4 2 PHD-finger ARID PF01388.21 KII95303.1 - 1.3e-14 54.6 0.0 3.7e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 KII95303.1 - 1.6e-14 54.0 9.4 1.6e-14 54.0 9.4 2.5 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 KII95303.1 - 3.9e-14 52.3 0.5 8.7e-14 51.2 0.5 1.7 1 0 0 1 1 1 1 jmjN domain HTH_31 PF13560.6 KII95303.1 - 0.005 17.2 1.3 0.015 15.6 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain Mis12 PF05859.12 KII95304.1 - 5.1e-36 123.7 0.4 7.5e-36 123.2 0.4 1.2 1 0 0 1 1 1 1 Mis12 protein DUF2508 PF10704.9 KII95304.1 - 0.015 15.4 0.3 0.033 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) TAtT PF16811.5 KII95304.1 - 0.3 10.3 1.3 0.45 9.8 1.3 1.2 1 0 0 1 1 1 0 TRAP transporter T-component F-box-like PF12937.7 KII95305.1 - 8.2e-05 22.4 1.8 0.097 12.6 0.2 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 KII95305.1 - 0.42 10.6 2.1 5.1 7.1 0.2 2.7 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.22 KII95306.1 - 9.6e-10 38.2 0.1 1.8e-06 27.7 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 KII95306.1 - 3.4 7.8 6.8 1.5 8.9 1.7 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 INT_SG_DDX_CT_C PF15300.6 KII95307.1 - 0.051 13.4 0.5 0.2 11.5 0.3 1.9 1 1 1 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus SPATA3 PF15662.5 KII95308.1 - 8.5 7.0 15.7 14 6.3 15.7 1.3 1 1 0 1 1 1 0 Spermatogenesis-associated protein 3 family F-box-like PF12937.7 KII95309.1 - 2.3e-05 24.2 3.8 0.12 12.3 0.4 3.4 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 KII95311.1 - 1.6e-05 24.7 0.2 5.6e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 F-box-like F-box PF00646.33 KII95311.1 - 3.3e-05 23.6 0.2 0.00024 20.9 0.0 2.1 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 KII95311.1 - 0.0027 17.6 0.2 0.019 14.8 0.1 2.1 1 1 1 2 2 2 1 F-box Sds3 PF08598.11 KII95312.1 - 0.00031 20.8 0.0 0.0005 20.1 0.0 1.4 1 1 0 1 1 1 1 Sds3-like F-box-like PF12937.7 KII95313.1 - 3.2e-05 23.7 2.5 0.00068 19.5 2.5 2.5 1 1 0 1 1 1 1 F-box-like CDC14 PF08045.11 KII95314.1 - 2.5e-32 112.1 0.1 2.8e-27 95.6 0.1 3.1 2 1 0 2 2 2 2 Cell division control protein 14, SIN component Chorion_2 PF03964.15 KII95314.1 - 1.9 9.4 10.5 35 5.3 7.0 2.5 2 0 0 2 2 2 0 Chorion family 2 SPX PF03105.19 KII95314.1 - 5.2 6.9 8.4 8.9 6.1 8.4 1.4 1 0 0 1 1 1 0 SPX domain Aldedh PF00171.22 KII95315.1 - 1e-160 535.3 3.4 1.1e-160 535.1 3.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UPF0029 PF01205.19 KII95316.1 - 1.1e-28 99.6 0.0 1.7e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KII95316.1 - 5.9e-08 33.0 0.0 9.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-CCCH_4 PF18044.1 KII95317.1 - 0.00019 21.2 2.7 0.00019 21.2 2.7 3.5 2 1 2 4 4 4 1 CCCH-type zinc finger zf-CCCH PF00642.24 KII95317.1 - 0.00082 19.2 2.3 0.00082 19.2 2.3 3.8 2 1 2 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII95317.1 - 0.032 14.3 3.1 0.032 14.3 3.1 3.6 3 1 1 4 4 4 0 Zinc finger domain bZIP_2 PF07716.15 KII95317.1 - 0.037 14.1 1.9 0.087 12.9 1.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Ax_dynein_light PF10211.9 KII95317.1 - 0.066 13.1 1.6 0.14 12.1 1.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.12 KII95317.1 - 0.12 12.4 7.2 0.21 11.6 7.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KII95317.1 - 0.13 9.8 2.7 0.17 9.4 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mod_r PF07200.13 KII95317.1 - 0.16 12.0 3.5 0.28 11.3 3.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zf-CCCH PF00642.24 KII95318.1 - 0.007 16.3 25.0 0.01 15.7 3.3 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII95318.1 - 0.056 13.5 1.7 0.056 13.5 1.7 3.9 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_4 PF18044.1 KII95318.1 - 7.6 6.5 18.4 6.7 6.6 4.1 3.5 2 1 1 3 3 3 0 CCCH-type zinc finger Rho_GDI PF02115.17 KII95319.1 - 2.7e-53 180.6 0.0 3.2e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UbiA PF01040.18 KII95320.1 - 2.9e-54 184.0 14.9 3.6e-54 183.7 14.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ytp1 PF10355.9 KII95321.1 - 5.8e-90 301.3 6.9 7.3e-67 225.5 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KII95321.1 - 0.0051 16.6 3.8 0.0051 16.6 3.8 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) MFS_1 PF07690.16 KII95323.1 - 1.6e-35 122.7 19.3 1.6e-35 122.7 19.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KII95323.1 - 2.1e-05 24.0 0.9 2.1e-05 24.0 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4234 PF14018.6 KII95323.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4234) cNMP_binding PF00027.29 KII95325.1 - 2.5e-30 104.4 0.3 4.8e-15 55.4 0.0 3.3 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KII95325.1 - 4.5e-08 32.6 0.4 8.9e-08 31.7 0.4 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Fibrinogen_aC PF12160.8 KII95325.1 - 0.066 13.1 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain ubiquitin PF00240.23 KII95326.1 - 7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Glyco_hydro_9 PF00759.19 KII95327.1 - 2.6e-112 376.3 15.6 3.1e-112 376.0 15.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.10 KII95327.1 - 0.0046 16.3 3.6 0.0094 15.3 3.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KII95327.1 - 0.05 13.5 0.9 0.089 12.6 0.9 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Dicer_dimer PF03368.14 KII95327.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Dicer dimerisation domain FAD_binding_1 PF00667.20 KII95328.1 - 1.9e-53 181.3 0.0 2.7e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KII95328.1 - 2.9e-08 34.3 0.0 7.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KII95328.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.24 KII95328.1 - 0.082 13.3 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain GFO_IDH_MocA PF01408.22 KII95329.1 - 7.1e-23 81.7 0.0 1.7e-22 80.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII95329.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain UPRTase PF14681.6 KII95330.1 - 2.4e-68 229.6 0.0 2.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_8 PF05148.15 KII95331.1 - 3.7e-65 219.9 0.0 7.1e-65 218.9 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KII95331.1 - 3.5e-07 30.8 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KII95331.1 - 6e-05 23.7 0.0 0.00014 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII95331.1 - 0.019 14.8 0.0 8.3 6.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Mucin PF01456.17 KII95331.1 - 0.4 10.7 5.0 0.62 10.0 5.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1631 PF07793.11 KII95331.1 - 1.1 7.6 4.2 1.3 7.4 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AAA_22 PF13401.6 KII95332.1 - 0.0002 21.6 0.1 0.76 10.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain Zot PF05707.12 KII95332.1 - 0.0032 17.2 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.29 KII95332.1 - 0.0037 17.7 0.0 0.093 13.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KII95332.1 - 0.011 16.1 0.0 3.8 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Av_adeno_fibre PF06536.11 KII95332.1 - 0.022 14.6 0.1 0.062 13.2 0.1 1.7 2 0 0 2 2 2 0 Avian adenovirus fibre, N-terminal FtsK_SpoIIIE PF01580.18 KII95332.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 KII95332.1 - 0.11 12.6 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KII95332.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mito_fiss_reg PF05308.11 KII95332.1 - 7.1 6.6 5.6 12 5.9 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.25 KII95333.1 - 2.7e-34 118.4 0.0 3.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95333.1 - 1.6e-24 86.8 0.0 2e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KII95333.1 - 8.2e-11 42.1 0.4 3e-10 40.3 0.4 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KII95333.1 - 0.036 13.5 0.0 0.17 11.3 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KII95335.1 - 4.9e-69 232.6 0.0 1.1e-68 231.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95335.1 - 2.4e-30 105.7 0.0 6e-29 101.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII95335.1 - 0.0031 16.9 2.5 0.79 9.0 0.5 2.9 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KII95335.1 - 0.0043 16.7 0.1 0.007 16.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KII95335.1 - 0.065 12.0 0.0 0.13 11.0 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase WD40 PF00400.32 KII95337.1 - 1.4e-06 28.9 2.3 0.57 11.1 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 KII95337.1 - 1.9e-05 23.8 0.0 0.00027 20.0 0.0 2.1 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Peptidase_M28 PF04389.17 KII95340.1 - 4.1e-27 95.1 0.1 5.9e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KII95340.1 - 5e-06 26.4 0.0 9e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 BRX_assoc PF16627.5 KII95340.1 - 0.19 11.9 0.9 5.2 7.3 0.2 2.8 3 0 0 3 3 3 0 Unstructured region between BRX_N and BRX domain Ribosomal_L11 PF00298.19 KII95341.1 - 1.5e-29 102.3 1.4 2.2e-29 101.8 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KII95341.1 - 2.8e-25 87.9 0.7 4.9e-25 87.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain KorB PF08535.10 KII95343.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 KorB domain Glyco_hydro_cc PF11790.8 KII95344.1 - 1.7e-63 214.4 4.0 1.9e-63 214.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RRM_1 PF00076.22 KII95345.1 - 4.2e-28 97.0 0.1 8.1e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 KII95345.1 - 3.8e-22 77.8 1.1 7.7e-22 76.8 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KII95345.1 - 0.00014 21.7 1.1 0.00037 20.3 0.3 2.1 2 0 0 2 2 2 1 G-patch domain DbpA PF03880.15 KII95345.1 - 0.0056 16.7 0.2 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_5 PF13893.6 KII95345.1 - 0.047 13.3 0.0 5.5 6.6 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4944 PF16302.5 KII95345.1 - 0.14 12.2 0.6 21 5.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) DNA_RNApol_7kD PF03604.13 KII95347.1 - 2.2e-17 62.4 7.6 2.8e-17 62.1 7.6 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 KII95347.1 - 0.0031 17.5 0.1 0.0032 17.5 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KII95347.1 - 0.0039 17.2 0.5 0.0058 16.6 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_10 PF10058.9 KII95347.1 - 0.0051 16.5 0.3 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 KII95347.1 - 0.0083 16.2 2.9 0.017 15.2 2.9 1.5 1 1 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KII95347.1 - 0.012 15.3 1.1 0.033 13.9 1.1 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-ISL3 PF14690.6 KII95347.1 - 0.013 16.1 1.9 0.064 13.9 0.3 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC PF07967.13 KII95347.1 - 0.019 15.0 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like Zn_ribbon_recom PF13408.6 KII95347.1 - 0.02 15.4 3.1 0.31 11.6 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.11 KII95347.1 - 0.025 14.5 0.7 0.032 14.2 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc-ribbon_6 PF10005.9 KII95347.1 - 0.025 15.2 0.3 0.04 14.6 0.3 1.4 1 1 0 1 1 1 0 zinc-ribbon domain MCM_OB PF17207.3 KII95347.1 - 0.032 14.1 0.6 0.039 13.8 0.6 1.1 1 0 0 1 1 1 0 MCM OB domain TF_Zn_Ribbon PF08271.12 KII95347.1 - 0.04 13.4 2.1 0.66 9.5 0.1 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.6 KII95347.1 - 0.043 13.7 5.6 0.74 9.8 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain NinF PF05810.12 KII95347.1 - 0.046 13.6 0.2 0.061 13.2 0.2 1.2 1 0 0 1 1 1 0 NinF protein zf_UBZ PF18439.1 KII95347.1 - 0.14 11.8 2.1 6 6.5 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Sec23_Sec24 PF04810.15 KII95347.1 - 0.38 10.9 2.5 17 5.5 1.5 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin_2 PF18073.1 KII95347.1 - 0.49 10.2 3.9 6.9 6.5 0.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Phage_holin_2_1 PF04971.12 KII95348.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage P21 holin S DUF3425 PF11905.8 KII95350.1 - 5.5e-14 52.2 0.1 3.9e-13 49.5 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KII95350.1 - 6e-09 35.9 4.9 1.5e-08 34.6 4.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII95350.1 - 0.0035 17.4 8.8 0.004 17.2 3.4 2.4 2 0 0 2 2 2 1 Basic region leucine zipper DUF5101 PF17031.5 KII95350.1 - 0.042 13.9 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Ribosomal_S14 PF00253.21 KII95351.1 - 1.1e-21 76.3 0.3 1.7e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e COA2 PF17051.5 KII95352.1 - 8.1e-05 22.6 0.0 8.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 MFS_1 PF07690.16 KII95353.1 - 1.4e-23 83.4 43.4 1.7e-22 79.9 40.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KII95354.1 - 2.1e-72 243.7 0.0 2.6e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95354.1 - 7.5e-29 100.8 0.0 4.1e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KII95354.1 - 6.2e-10 38.9 0.1 0.07 12.4 0.0 3.0 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KII95354.1 - 0.00018 20.4 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KII95354.1 - 0.022 14.7 0.0 0.72 9.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KII95354.1 - 0.039 13.3 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 KII95355.1 - 3.4e-18 66.1 0.0 6.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding SNARE_assoc PF09335.11 KII95356.1 - 3.2e-13 50.2 6.8 3.2e-13 50.2 6.8 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2076 PF09849.9 KII95357.1 - 0.00048 20.2 0.1 0.00066 19.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1192 PF06698.11 KII95357.1 - 0.007 16.4 1.1 0.013 15.6 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF4140 PF13600.6 KII95357.1 - 0.027 14.9 0.1 0.034 14.6 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spore_III_AB PF09548.10 KII95357.1 - 0.042 14.0 0.1 0.07 13.2 0.0 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DMPK_coil PF08826.10 KII95357.1 - 0.053 13.6 1.8 0.079 13.1 1.8 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF4391 PF14335.6 KII95357.1 - 0.055 13.2 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF948 PF06103.11 KII95357.1 - 0.064 13.5 0.0 0.084 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Cast PF10174.9 KII95357.1 - 0.078 11.2 0.2 0.095 10.9 0.2 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DivIC PF04977.15 KII95357.1 - 0.098 12.4 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Cep57_CLD_2 PF14197.6 KII95357.1 - 0.11 12.6 1.9 0.17 12.0 1.9 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 PEX11 PF05648.14 KII95358.1 - 8.4e-12 45.0 3.9 6.5e-11 42.1 0.9 3.0 1 1 1 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Peroxin-3 PF04882.12 KII95358.1 - 0.0089 15.1 0.3 0.013 14.5 0.3 1.2 1 0 0 1 1 1 1 Peroxin-3 Myc_N PF01056.18 KII95358.1 - 0.054 13.4 1.2 0.086 12.7 1.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Tctex-1 PF03645.13 KII95359.1 - 3.2e-14 53.0 0.0 4e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.16 KII95361.1 - 6.8e-32 110.8 26.7 9.7e-32 110.2 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KII95362.1 - 8.5e-88 294.7 0.0 9.7e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Nop PF01798.18 KII95363.1 - 2e-66 223.8 0.0 3.2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KII95363.1 - 1.6e-38 132.4 7.0 3.6e-38 131.2 7.0 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain NifU_N PF01592.16 KII95364.1 - 4.9e-53 178.7 0.1 7.5e-53 178.1 0.1 1.3 1 1 0 1 1 1 1 NifU-like N terminal domain COG6 PF06419.11 KII95365.1 - 1.5e-154 515.7 0.0 2e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF1664 PF07889.12 KII95365.1 - 0.042 13.9 0.9 0.14 12.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KII95365.1 - 0.077 11.1 3.2 0.13 10.4 3.2 1.3 1 0 0 1 1 1 0 HOOK protein Sec3_C PF09763.9 KII95365.1 - 0.45 8.8 2.8 1.5 7.1 0.7 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 Mannosyl_trans PF05007.13 KII95366.1 - 1.6e-79 267.5 13.9 2e-79 267.1 13.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KII95366.1 - 5.6e-14 52.0 12.6 5.2e-13 48.8 12.6 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KII95366.1 - 1.6e-07 31.3 9.2 1.6e-07 31.3 9.2 2.2 1 1 1 2 2 2 1 Glycosyltransferase family 87 TFIID-31kDa PF02291.15 KII95367.1 - 5.3e-36 123.4 0.0 8.1e-36 122.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KII95367.1 - 0.00017 21.9 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KII95367.1 - 0.00025 21.1 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KII95367.1 - 0.0005 20.0 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KII95367.1 - 0.078 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma70_ner PF04546.13 KII95367.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.2 1 1 1 2 2 2 0 Sigma-70, non-essential region BSP_II PF05432.11 KII95367.1 - 3 7.5 19.3 4.3 7.0 19.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) BUD22 PF09073.10 KII95367.1 - 8.6 5.6 11.8 11 5.2 11.8 1.1 1 0 0 1 1 1 0 BUD22 WD40 PF00400.32 KII95368.1 - 5.6e-12 46.0 0.0 0.00013 22.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95368.1 - 0.011 16.0 0.0 6.2 7.2 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mg_trans_NIPA PF05653.14 KII95369.1 - 2.5e-58 197.5 12.9 1.9e-54 184.8 10.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KII95369.1 - 0.00032 20.9 2.1 0.00032 20.9 2.1 3.0 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KII95369.1 - 0.48 9.9 9.0 0.036 13.6 2.7 1.8 1 1 1 2 2 2 0 Solute carrier family 35 NUFIP1 PF10453.9 KII95370.1 - 0.023 14.6 0.6 0.023 14.6 0.6 1.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) C2 PF00168.30 KII95371.1 - 1.3e-14 54.4 0.0 1.2e-10 41.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain Ceramidase PF05875.12 KII95372.1 - 1.7e-72 244.1 2.4 1.9e-72 243.9 2.4 1.0 1 0 0 1 1 1 1 Ceramidase EamA PF00892.20 KII95372.1 - 0.0091 16.2 4.2 0.078 13.2 0.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family GPI2 PF06432.11 KII95372.1 - 0.13 11.7 1.2 0.27 10.6 1.1 1.7 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Glyco_hydro_125 PF06824.11 KII95373.1 - 9.4e-151 502.4 0.6 1.1e-150 502.1 0.6 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) F-box-like PF12937.7 KII95374.1 - 4.9e-08 32.7 0.4 2.4e-07 30.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like ABC_tran_CTD PF16326.5 KII95374.1 - 0.029 14.6 0.1 0.057 13.7 0.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain F-box-like PF12937.7 KII95375.1 - 9.7e-08 31.8 0.7 9.7e-08 31.8 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII95375.1 - 0.047 13.6 2.7 0.6 10.1 2.7 2.6 1 1 0 1 1 1 0 F-box domain CBP_BcsG PF11658.8 KII95375.1 - 0.2 10.0 0.0 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Aconitase PF00330.20 KII95377.1 - 2.5e-157 524.6 0.0 2.9e-157 524.4 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KII95377.1 - 1.2e-39 135.6 0.0 1.9e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.17 KII95378.1 - 7.5e-20 71.0 9.2 1.3e-19 70.2 9.2 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Tau95 PF09734.9 KII95379.1 - 8.4e-37 127.1 1.2 8.4e-37 127.1 1.2 2.3 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KII95379.1 - 4e-28 98.1 0.0 9e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain SBP_bac_5 PF00496.22 KII95380.1 - 0.013 14.5 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Sld5 PF05916.11 KII95381.1 - 3.1e-06 27.6 0.0 4.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Pkr1 PF08636.10 KII95382.1 - 7e-19 67.7 4.7 8.4e-19 67.5 4.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Pkinase_Tyr PF07714.17 KII95384.1 - 1.1e-31 110.1 0.0 2.7e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KII95384.1 - 6.1e-28 97.9 0.0 1.2e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MarR_2 PF12802.7 KII95384.1 - 0.14 12.0 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 MarR family MDM10 PF12519.8 KII95385.1 - 2e-98 330.3 0.4 1.7e-87 294.2 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KII95385.1 - 0.043 13.3 0.0 1.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic porin LSM PF01423.22 KII95387.1 - 1.8e-19 69.1 0.0 2.1e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KII95387.1 - 0.047 13.3 0.0 0.071 12.8 0.0 1.3 1 1 0 1 1 1 0 Hfq protein TPMT PF05724.11 KII95388.1 - 1.8e-36 125.8 0.0 2.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KII95388.1 - 3e-09 37.5 0.0 1e-07 32.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII95388.1 - 9.4e-07 29.4 0.0 5.2e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII95388.1 - 3.2e-06 27.8 0.0 4.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII95388.1 - 5.6e-06 26.3 0.0 6.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII95388.1 - 7.6e-05 22.6 0.0 0.00053 19.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KII95388.1 - 0.099 12.0 0.0 1.9 7.9 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB PPR_2 PF13041.6 KII95389.1 - 4.5e-10 39.5 0.0 0.00098 19.3 0.0 3.9 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KII95389.1 - 1.7e-06 28.0 0.0 0.0019 18.2 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 KII95389.1 - 0.00024 21.2 1.2 1.5 9.2 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 KII95389.1 - 0.00052 19.7 0.0 0.027 14.2 0.0 3.1 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 KII95389.1 - 0.035 13.5 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP DUF1275 PF06912.11 KII95390.1 - 5e-25 88.5 14.9 7.6e-25 88.0 14.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) COesterase PF00135.28 KII95394.1 - 8.8e-69 232.7 0.0 3.4e-58 197.8 0.0 2.3 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KII95394.1 - 0.0035 17.2 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII95394.1 - 0.016 14.7 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family CoA_transf_3 PF02515.17 KII95395.1 - 1.3e-104 350.3 0.0 1.5e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III RNA_pol_A_bac PF01000.26 KII95397.1 - 1.1e-22 80.5 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KII95397.1 - 3.2e-18 64.9 0.0 4.2e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain fn3 PF00041.21 KII95397.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain Pho86 PF11124.8 KII95399.1 - 0.11 12.0 3.9 0.18 11.3 3.9 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF3464 PF11947.8 KII95399.1 - 0.27 11.0 0.7 0.55 10.0 0.7 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Fez1 PF06818.15 KII95400.1 - 0.00093 19.7 2.0 0.0018 18.8 2.0 1.4 1 0 0 1 1 1 1 Fez1 DUF3450 PF11932.8 KII95400.1 - 0.0018 17.6 3.7 0.0033 16.8 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CCDC154 PF15450.6 KII95400.1 - 0.0079 14.8 2.2 0.012 14.2 2.2 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 ATG16 PF08614.11 KII95400.1 - 0.013 15.8 9.4 0.013 15.8 9.4 2.0 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 KII95400.1 - 0.013 15.5 7.1 0.023 14.8 7.1 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Filament PF00038.21 KII95400.1 - 0.016 14.8 1.4 0.025 14.2 1.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 KII95400.1 - 0.022 14.9 5.6 0.041 14.0 5.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 KII95400.1 - 0.024 14.7 0.2 0.024 14.7 0.2 2.8 3 0 0 3 3 2 0 bZIP transcription factor HAP1_N PF04849.13 KII95400.1 - 0.033 13.4 5.4 0.048 12.9 5.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DivIC PF04977.15 KII95400.1 - 0.039 13.7 11.2 0.27 11.0 1.1 2.8 2 1 0 3 3 2 0 Septum formation initiator Spc7 PF08317.11 KII95400.1 - 0.059 12.2 7.1 0.11 11.3 7.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KII95400.1 - 0.085 13.3 11.6 1.6 9.2 2.1 2.8 1 1 0 2 2 2 0 Cell division protein ZapB Taxilin PF09728.9 KII95400.1 - 0.11 11.7 4.3 0.15 11.2 4.3 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.12 KII95400.1 - 0.17 12.0 6.6 0.28 11.2 6.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.9 KII95400.1 - 0.19 11.1 5.8 0.37 10.1 5.8 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 GAS PF13851.6 KII95400.1 - 0.2 11.0 6.8 0.35 10.2 6.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KII95400.1 - 0.24 12.0 5.9 0.98 10.1 2.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA BicD PF09730.9 KII95400.1 - 0.4 9.1 12.3 0.015 13.8 5.9 1.7 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF1664 PF07889.12 KII95400.1 - 0.41 10.7 1.7 1.8 8.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KII95400.1 - 0.42 11.2 3.8 0.4 11.3 0.5 2.5 1 1 0 2 2 2 0 SlyX NYD-SP28_assoc PF14775.6 KII95400.1 - 0.47 10.6 6.4 1.3 9.1 0.6 2.9 2 1 0 2 2 2 0 Sperm tail C-terminal domain CENP-F_leu_zip PF10473.9 KII95400.1 - 0.5 10.4 9.1 0.43 10.6 1.7 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 KII95400.1 - 0.61 10.3 6.7 5.5 7.2 3.2 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KII95400.1 - 1.2 9.4 9.6 17 5.6 9.0 2.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KII95400.1 - 1.2 9.1 10.2 1.9 8.5 2.0 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 KII95400.1 - 1.7 8.5 5.3 3.3 7.6 5.3 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 KII95400.1 - 1.9 8.7 4.7 5.6 7.3 4.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 KII95400.1 - 2.1 8.4 4.5 3.7 7.6 4.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 KII95400.1 - 2.2 7.5 3.6 3.7 6.8 3.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KII95400.1 - 3.8 8.1 13.1 18 5.9 4.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KII95400.1 - 4.3 8.3 8.1 4 8.4 1.2 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 KII95400.1 - 6.7 7.2 7.0 22 5.5 7.0 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 KII95400.1 - 7 6.4 12.0 0.58 10.0 6.9 1.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH G-alpha PF00503.20 KII95402.1 - 3.5e-115 384.9 0.3 4e-115 384.8 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KII95402.1 - 5e-15 55.4 0.4 7.7e-10 38.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KII95402.1 - 9.9e-05 21.8 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KII95402.1 - 0.009 16.2 0.3 1.8 8.8 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KII95402.1 - 0.21 11.3 0.4 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain PilZ_2 PF16823.5 KII95404.1 - 0.00047 20.3 0.5 0.0011 19.2 0.5 1.5 1 0 0 1 1 1 1 Atypical PilZ domain, cyclic di-GMP receptor BTB PF00651.31 KII95404.1 - 0.0074 16.5 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Importin_rep_4 PF18808.1 KII95405.1 - 2.6e-19 69.3 0.3 1.4e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KII95405.1 - 8.3e-17 61.3 13.8 7.9e-10 39.0 0.2 6.6 6 1 1 7 7 6 3 HEAT-like repeat HEAT PF02985.22 KII95405.1 - 9.4e-12 44.1 11.0 4.1e-05 23.5 0.1 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 KII95405.1 - 8.8e-10 38.8 7.6 2e-05 24.9 0.0 5.5 4 2 1 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KII95405.1 - 1.1e-08 35.5 0.0 0.00044 20.8 0.0 3.8 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KII95405.1 - 0.00012 22.1 0.0 0.3 11.0 0.0 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KII95405.1 - 0.00023 21.3 0.0 0.0028 17.7 0.0 2.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 KII95405.1 - 0.00048 19.4 0.8 0.02 14.1 0.1 3.3 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 KII95405.1 - 0.00099 17.8 0.0 0.0027 16.4 0.0 1.8 2 0 0 2 2 2 1 Adaptin N terminal region MMS19_C PF12460.8 KII95405.1 - 0.006 15.7 3.9 0.033 13.3 0.2 3.3 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal DUF4042 PF13251.6 KII95405.1 - 0.012 15.3 0.0 0.93 9.2 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) RIX1 PF08167.12 KII95405.1 - 0.026 14.2 2.6 0.54 10.0 0.1 3.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 KII95405.1 - 0.041 13.9 0.5 13 6.0 0.0 4.4 3 1 0 3 3 3 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KII95405.1 - 0.067 13.4 0.2 3.9 7.7 0.0 3.2 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3455 PF11937.8 KII95406.1 - 1.7e-24 87.0 0.2 2.3e-24 86.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3136 PF11334.8 KII95407.1 - 4.6 7.1 6.2 46 3.9 0.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3136) Plavaka PF18759.1 KII95409.1 - 2.4e-36 125.6 0.0 4.2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase DUF3619 PF12279.8 KII95409.1 - 0.13 12.5 2.9 5.7 7.3 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) gag-asp_proteas PF13975.6 KII95411.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KII95411.1 - 0.032 14.9 0.0 0.089 13.4 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 KII95412.1 - 0.099 12.8 2.3 0.28 11.4 2.3 1.8 1 1 0 1 1 1 0 Zinc knuckle zf-MYND PF01753.18 KII95415.1 - 1.1e-05 25.4 11.4 2.2e-05 24.4 11.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII95415.1 - 2.9 8.3 7.7 6.4 7.2 7.7 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cpn60_TCP1 PF00118.24 KII95416.1 - 3.1e-145 484.6 3.6 3.5e-145 484.4 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 KII95416.1 - 0.07 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 EAL domain Alpha_L_fucos PF01120.17 KII95420.1 - 4e-71 240.3 0.9 5.2e-71 239.9 0.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase RhoGAP PF00620.27 KII95421.1 - 1.9e-42 144.7 0.0 3.9e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 KII95421.1 - 1.1e-10 42.0 0.0 4.4e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain PH_9 PF15410.6 KII95421.1 - 2.7e-09 37.4 0.0 2.8e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain RasGEF_N PF00618.20 KII95421.1 - 3.1e-09 37.0 0.1 2.5e-08 34.1 0.0 2.7 3 1 0 3 3 3 1 RasGEF N-terminal motif PH PF00169.29 KII95421.1 - 9.7e-07 29.3 0.0 0.0003 21.3 0.0 2.5 2 0 0 2 2 2 2 PH domain F-box PF00646.33 KII95422.1 - 8.4e-06 25.5 0.2 3.8e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KII95422.1 - 0.00056 19.8 1.4 0.0012 18.7 0.4 2.0 2 0 0 2 2 2 1 F-box-like NAD_binding_5 PF07994.12 KII95424.1 - 1.5e-138 461.6 0.0 1.8e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KII95424.1 - 5.5e-45 152.1 0.0 1e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NIF PF03031.18 KII95425.1 - 1.1e-39 135.7 0.0 1.5e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF737 PF05300.11 KII95425.1 - 0.012 16.0 4.5 0.042 14.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Peptidase_M15_2 PF05951.13 KII95425.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Homeodomain PF00046.29 KII95426.1 - 6.2e-15 54.8 2.6 7.8e-15 54.5 1.5 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KII95426.1 - 0.0089 15.9 0.5 0.017 15.0 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.16 KII95429.1 - 7.9e-19 67.8 58.7 4e-18 65.5 33.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3455 PF11937.8 KII95430.1 - 2.1e-24 86.7 1.3 3.4e-24 86.0 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CFEM PF05730.11 KII95431.1 - 2.4e-06 27.5 9.4 5.1e-06 26.5 9.4 1.6 1 0 0 1 1 1 1 CFEM domain SPX PF03105.19 KII95431.1 - 0.61 9.9 11.1 0.79 9.6 11.1 1.0 1 0 0 1 1 1 0 SPX domain Gcn1_N PF12074.8 KII95432.1 - 9.5e-89 298.2 1.4 7e-88 295.3 0.0 3.1 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KII95432.1 - 3.2e-34 114.0 22.3 0.1 12.9 0.0 19.4 20 0 0 20 20 20 8 HEAT repeat HEAT_EZ PF13513.6 KII95432.1 - 4e-28 97.4 34.3 0.00057 20.3 0.0 17.3 17 3 4 21 21 21 6 HEAT-like repeat HEAT_2 PF13646.6 KII95432.1 - 8.9e-27 93.3 34.4 4.8e-05 23.7 0.0 14.3 12 2 1 15 15 14 7 HEAT repeats Cnd1 PF12717.7 KII95432.1 - 8e-13 48.7 0.0 0.78 9.8 0.1 9.6 8 3 2 10 10 10 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KII95432.1 - 7.6e-10 38.7 0.0 7.7e-05 22.4 0.0 6.1 5 2 2 7 7 7 1 CLASP N terminal Adaptin_N PF01602.20 KII95432.1 - 7.6e-08 31.4 0.0 0.043 12.4 0.1 6.5 7 1 1 8 8 8 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KII95432.1 - 6.5e-07 29.9 0.0 3.5 8.3 0.1 5.7 5 1 0 6 6 5 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KII95432.1 - 0.0003 20.0 5.1 0.97 8.5 0.0 6.6 8 0 0 8 8 8 1 Interferon-related developmental regulator (IFRD) DUF3535 PF12054.8 KII95432.1 - 0.00078 18.8 0.1 0.022 14.0 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) Arm PF00514.23 KII95432.1 - 0.0054 16.7 0.3 6.2 7.0 0.0 5.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KII95432.1 - 0.067 13.9 15.6 0.29 11.9 0.2 8.2 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KII95432.1 - 0.15 12.3 0.0 43 4.3 0.0 5.0 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 KII95432.1 - 10 6.6 16.5 3.4 8.1 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion 2OG-FeII_Oxy_3 PF13640.6 KII95433.1 - 5.8e-09 36.7 0.1 1.1e-08 35.9 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KII95433.1 - 0.019 15.6 0.0 0.039 14.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Dynamin_M PF01031.20 KII95434.1 - 7.3e-29 100.9 0.0 3.9e-28 98.5 0.0 1.9 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KII95434.1 - 1.4e-28 100.0 0.0 2.7e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KII95434.1 - 5.4e-12 45.7 0.0 3.1e-11 43.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KII95434.1 - 2.7e-05 24.2 0.0 0.00035 20.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KII95434.1 - 0.0012 19.3 0.1 0.013 15.8 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KII95434.1 - 0.0097 16.4 0.1 0.22 12.0 0.0 2.9 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KII95434.1 - 0.031 14.8 0.2 0.99 9.9 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KII95434.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NIR_SIR_ferr PF03460.17 KII95434.1 - 0.086 12.7 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain AAA_15 PF13175.6 KII95434.1 - 0.14 11.8 0.2 1 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain COesterase PF00135.28 KII95435.1 - 1.4e-88 298.1 0.0 2.2e-88 297.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KII95435.1 - 7.8e-05 22.6 0.1 0.00059 19.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII95435.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family 2OG-FeII_Oxy_3 PF13640.6 KII95437.1 - 3.6e-08 34.2 0.0 7.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ceramidase_alk PF04734.13 KII95439.1 - 1.6e-210 700.0 0.1 1.9e-210 699.8 0.1 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KII95439.1 - 3.4e-56 189.7 0.0 5.5e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal TEA PF01285.18 KII95441.1 - 2.1e-23 82.2 0.0 3.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain HycH PF07450.11 KII95443.1 - 0.055 13.8 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Cellulase PF00150.18 KII95444.1 - 0.00091 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pinin_SDK_memA PF04696.13 KII95445.1 - 3.1e-14 53.1 16.6 3.1e-14 53.1 16.6 3.3 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region RGS-like PF09128.11 KII95445.1 - 3.2 7.4 8.0 0.42 10.3 0.6 2.1 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain SRP_TPR_like PF17004.5 KII95446.1 - 1e-14 54.6 0.1 1.5e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 KII95446.1 - 1.8e-07 31.4 0.0 1.8e-07 31.4 0.0 2.8 3 0 0 3 3 3 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 KII95446.1 - 0.00014 22.0 1.0 0.044 14.0 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KII95446.1 - 0.002 18.6 0.3 0.22 12.0 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KII95446.1 - 0.014 15.4 0.7 33 4.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII95446.1 - 0.015 16.1 0.1 22 6.2 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII95446.1 - 0.044 13.9 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 KII95446.1 - 0.07 12.5 0.2 0.099 12.0 0.2 1.3 1 0 0 1 1 1 0 Coatomer epsilon subunit Peptidase_S10 PF00450.22 KII95448.1 - 2.7e-68 231.3 1.7 2.9e-67 227.9 1.7 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase FPN1 PF06963.12 KII95449.1 - 1.9e-106 356.2 14.1 2.5e-106 355.9 14.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) adh_short PF00106.25 KII95450.1 - 2.3e-05 24.0 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII95450.1 - 2.8e-05 24.1 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GST_C_6 PF17171.4 KII95450.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Na_H_Exchanger PF00999.21 KII95451.1 - 2.3e-53 181.4 45.7 3.1e-53 180.9 45.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DRIM PF07539.12 KII95453.1 - 2.1e-176 587.9 3.7 2.1e-176 587.9 3.7 4.1 4 1 0 4 4 4 1 Down-regulated in metastasis DUF3361 PF11841.8 KII95453.1 - 0.0042 17.0 0.6 15 5.5 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3361) CLASP_N PF12348.8 KII95453.1 - 0.012 15.2 2.7 0.52 9.8 0.1 3.9 2 1 1 3 3 3 0 CLASP N terminal DUF4042 PF13251.6 KII95453.1 - 0.018 14.8 2.5 9.5 5.9 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) MOR2-PAG1_C PF14225.6 KII95453.1 - 0.046 13.6 10.8 10 5.9 0.6 5.5 5 1 1 6 6 6 0 Cell morphogenesis C-terminal HEAT PF02985.22 KII95453.1 - 0.33 11.3 2.5 71 4.1 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat MMS19_N PF14500.6 KII95453.1 - 2 7.9 12.3 0.16 11.6 0.3 4.7 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II CTK3 PF12243.8 KII95454.1 - 1.6e-35 121.8 0.0 2.3e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KII95454.1 - 8.9e-26 89.9 3.9 1.8e-25 88.9 3.9 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus PI3K_P85_iSH2 PF16454.5 KII95455.1 - 0.01 15.5 8.3 0.017 14.7 8.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMPIT PF07851.13 KII95455.1 - 0.17 11.1 1.2 0.26 10.5 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Arm PF00514.23 KII95455.1 - 0.18 11.9 0.3 27 5.0 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HAP1_N PF04849.13 KII95455.1 - 0.34 10.1 14.8 0.86 8.7 13.7 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 KII95455.1 - 1 9.8 14.1 8.7 6.7 13.5 2.1 1 1 1 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 KII95455.1 - 1.6 8.8 11.3 0.42 10.6 7.6 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 KII95455.1 - 1.7 8.4 7.1 5.1 6.9 3.7 2.7 2 0 0 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 KII95455.1 - 2.1 7.8 14.3 0.053 13.1 7.2 1.9 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.9 KII95455.1 - 2.8 6.9 15.3 4 6.4 13.1 2.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 KII95455.1 - 2.8 7.2 5.0 4.3 6.6 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 KII95455.1 - 3.5 6.4 12.7 19 4.0 12.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1266 PF06889.11 KII95455.1 - 9.8 6.2 8.6 29 4.7 8.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) Reo_sigmaC_M PF17750.1 KII95456.1 - 0.002 17.9 0.2 1.4 8.8 0.0 2.7 2 0 0 2 2 2 2 Reovirus sigma C capsid protein triple beta spiral Peptidase_M22 PF00814.25 KII95456.1 - 0.0066 16.2 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Glycoprotease family SpoVS PF04232.12 KII95456.1 - 0.063 13.0 0.0 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) DUF4559 PF15112.6 KII95456.1 - 0.064 12.9 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF5619 PF18505.1 KII95456.1 - 0.097 12.7 0.0 22 5.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5619) FGGY_C PF02782.16 KII95456.1 - 0.11 12.2 0.0 7.9 6.2 0.0 3.0 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain YjgF_endoribonc PF14588.6 KII95456.1 - 0.11 12.6 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease Beta-lactamase PF00144.24 KII95457.1 - 8e-32 110.8 2.4 1.2e-20 74.1 1.7 2.4 1 1 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.8 KII95457.1 - 0.00017 22.0 0.2 0.00073 20.0 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Rsm22 PF09243.10 KII95457.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RNase_T PF00929.24 KII95459.1 - 3.5e-08 34.1 0.0 6.6e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Exonuclease Mito_carr PF00153.27 KII95460.1 - 4.9e-57 189.9 1.9 1.6e-21 76.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ARD PF03079.14 KII95462.1 - 6.5e-42 143.4 0.0 7.7e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KII95462.1 - 2.9e-09 36.5 0.0 5.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KII95462.1 - 4.8e-07 29.8 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KII95462.1 - 0.00024 20.7 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KII95462.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.6 KII95462.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_7 PF12973.7 KII95463.1 - 0.00025 20.9 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 KII95463.1 - 0.00063 19.4 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Cupin domain MTCP1 PF08991.10 KII95464.1 - 3.9e-19 68.6 5.2 4.4e-19 68.5 5.2 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KII95464.1 - 0.023 14.8 1.0 0.023 14.8 1.0 1.7 1 1 1 2 2 2 0 CHCH domain CX9C PF16860.5 KII95464.1 - 0.03 14.3 2.9 0.051 13.6 2.9 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HSR PF03172.13 KII95464.1 - 0.047 13.8 0.0 0.066 13.4 0.0 1.2 1 1 0 1 1 1 0 HSR domain FlbT PF07378.11 KII95464.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlbT EphA2_TM PF14575.6 KII95465.1 - 0.0013 19.6 0.1 0.0024 18.7 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KII95465.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.6 3 0 0 3 3 3 0 TMEM154 protein family Herpes_gE PF02480.16 KII95465.1 - 0.022 13.5 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Insulin_TMD PF17870.1 KII95465.1 - 0.2 11.8 0.9 0.33 11.0 0.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Beta-APP PF03494.13 KII95465.1 - 0.35 10.8 0.9 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) BTB PF00651.31 KII95467.1 - 1.3e-08 35.1 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KII95468.1 - 5.3e-32 111.1 22.7 8.6e-32 110.4 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII95468.1 - 1.5e-07 30.7 23.4 1.3e-06 27.5 23.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.27 KII95469.1 - 7.1e-33 114.0 0.0 6.7e-18 65.5 0.0 3.3 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KII95469.1 - 6.1e-11 42.7 0.1 0.0023 17.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KII95469.1 - 0.00053 19.7 0.9 0.0022 17.7 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KII95469.1 - 0.00071 19.8 0.0 1 9.7 0.0 3.2 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 KII95469.1 - 0.0023 17.4 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KII95469.1 - 0.022 15.0 0.0 0.18 12.1 0.0 2.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 KII95469.1 - 0.079 13.4 0.3 0.14 12.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KII95469.1 - 0.18 11.7 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KII95469.1 - 0.19 11.6 0.0 0.98 9.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 KII95469.1 - 0.26 11.0 0.0 0.37 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 KII95469.1 - 0.34 8.4 0.0 0.49 7.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_28 PF13521.6 KII95469.1 - 0.59 10.4 4.3 1 9.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain Peptidase_M28 PF04389.17 KII95471.1 - 3.3e-34 118.3 0.0 8.7e-34 116.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 KII95471.1 - 0.011 14.7 0.0 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Glyco_hydro_16 PF00722.21 KII95473.1 - 0.0018 17.8 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WD40 PF00400.32 KII95475.1 - 2.7e-17 62.8 16.9 0.0003 21.5 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95475.1 - 1.5e-14 54.1 3.2 0.00013 22.2 0.2 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII95475.1 - 0.00041 20.3 0.3 0.02 14.8 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Bromodomain PF00439.25 KII95476.1 - 2.3e-21 75.6 0.3 4.5e-21 74.7 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KII95476.1 - 6.4e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated EF-hand_1 PF00036.32 KII95477.1 - 9.1e-23 78.1 0.6 1.8e-06 27.1 0.0 4.8 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 KII95477.1 - 5.6e-21 72.6 0.4 1.4e-06 27.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KII95477.1 - 2.5e-20 72.7 0.9 1.1e-08 35.3 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KII95477.1 - 9.2e-18 62.9 0.6 0.00043 19.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KII95477.1 - 1.6e-15 56.7 1.3 1.5e-07 31.1 0.1 3.9 3 2 1 4 4 4 3 EF-hand domain pair DUF2333 PF10095.9 KII95477.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) EF-hand_9 PF14658.6 KII95477.1 - 0.11 12.8 0.1 14 6.1 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain TGF_beta_GS PF08515.12 KII95479.1 - 0.67 9.5 7.9 1 8.9 6.3 2.1 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Uso1_p115_head PF04869.14 KII95481.1 - 1.3e-47 162.4 0.0 6e-46 157.0 0.0 2.9 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KII95481.1 - 2e-13 50.8 15.6 3.3e-13 50.1 15.6 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Med21 PF11221.8 KII95481.1 - 0.00038 20.7 0.1 0.00086 19.6 0.1 1.6 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Golgin_A5 PF09787.9 KII95481.1 - 0.0053 16.3 5.4 0.0087 15.6 5.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3818 PF12825.7 KII95481.1 - 0.024 13.7 1.8 0.04 12.9 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) COMP PF11598.8 KII95481.1 - 0.083 13.4 0.3 0.24 11.9 0.3 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Spc7 PF08317.11 KII95481.1 - 0.096 11.6 8.4 0.15 11.0 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lectin_N PF03954.14 KII95481.1 - 0.13 12.0 2.8 0.33 10.7 2.8 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain CwsA PF10814.8 KII95481.1 - 0.14 12.4 1.5 0.49 10.6 1.4 2.0 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA MIF4G_like_2 PF09090.11 KII95481.1 - 0.44 10.0 3.8 0.83 9.1 3.8 1.4 1 0 0 1 1 1 0 MIF4G like POX PF07526.11 KII95481.1 - 0.55 10.8 4.0 1 9.9 4.0 1.4 1 0 0 1 1 1 0 Associated with HOX Com_YlbF PF06133.11 KII95481.1 - 0.66 10.6 5.3 25 5.6 2.9 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA SlyX PF04102.12 KII95481.1 - 0.8 10.4 7.3 1.2 9.9 1.0 2.9 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 KII95481.1 - 2.2 8.6 7.6 2.7 8.3 5.8 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Aminotran_5 PF00266.19 KII95482.1 - 7.9e-31 107.3 0.0 4.3e-29 101.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V PseudoU_synth_2 PF00849.22 KII95483.1 - 1.4e-28 100.0 0.0 2.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cwf_Cwc_15 PF04889.12 KII95484.1 - 6.8e-86 288.0 22.1 7.7e-86 287.8 22.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 KII95484.1 - 0.00056 19.5 21.2 0.00066 19.2 21.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 KII95484.1 - 0.0034 15.7 22.1 0.0043 15.4 22.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 KII95484.1 - 0.95 7.7 21.5 1.2 7.4 21.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PA26 PF04636.13 KII95484.1 - 1.1 8.0 3.5 1.3 7.9 3.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 KII95484.1 - 1.3 8.8 18.1 1.7 8.4 18.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 KII95484.1 - 1.8 7.2 9.2 1.9 7.2 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 KII95484.1 - 1.9 7.2 3.2 2.3 7.0 3.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SpoIIIAH PF12685.7 KII95484.1 - 2.2 8.0 13.7 3.1 7.6 13.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF913 PF06025.12 KII95484.1 - 3.3 6.6 5.6 4 6.3 5.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SprA-related PF12118.8 KII95484.1 - 3.9 6.5 16.0 4.9 6.2 16.0 1.2 1 0 0 1 1 1 0 SprA-related family Sporozoite_P67 PF05642.11 KII95484.1 - 4.3 5.3 7.2 6.5 4.7 7.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 KII95484.1 - 4.6 7.1 23.5 8.7 6.2 23.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2167 PF09935.9 KII95484.1 - 7.8 5.6 10.0 0.38 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Hid1 PF12722.7 KII95484.1 - 8.1 4.4 6.5 9.3 4.2 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RhoGEF PF00621.20 KII95485.1 - 3.4e-30 105.7 0.0 5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FAD_binding_4 PF01565.23 KII95486.1 - 1.6e-11 44.1 0.1 8.5e-05 22.3 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KII95486.1 - 6.4e-08 32.6 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KII95486.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.14 KII95486.1 - 0.095 12.5 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase ATF7IP_BD PF16788.5 KII95487.1 - 5 7.2 7.3 13 5.8 7.3 1.7 1 0 0 1 1 1 0 ATF-interacting protein binding domain E1-E2_ATPase PF00122.20 KII95488.1 - 3e-50 170.3 0.6 3e-50 170.3 0.6 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KII95488.1 - 2.5e-39 134.9 1.3 6.3e-39 133.6 1.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KII95488.1 - 1e-19 71.7 0.4 1e-16 61.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KII95488.1 - 5.6e-14 52.0 0.0 1.7e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KII95488.1 - 6e-10 38.7 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KII95488.1 - 4.6e-05 23.3 1.4 0.001 18.9 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 KII95488.1 - 0.00054 19.9 1.3 0.011 15.7 0.0 3.1 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC HAD PF12710.7 KII95488.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 KII95488.1 - 1.1 9.3 4.3 5.3 7.0 0.2 2.6 1 1 1 2 2 2 0 CoA-binding domain Hydrolase_4 PF12146.8 KII95489.1 - 9.7e-13 47.9 0.1 1.2e-09 37.8 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII95489.1 - 5.5e-11 43.5 0.5 5.5e-11 43.5 0.5 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII95489.1 - 1.9e-08 34.3 0.0 1.5e-06 28.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KII95489.1 - 4.6e-08 33.2 0.2 1e-07 32.0 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KII95489.1 - 0.00036 20.1 0.0 0.00065 19.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KII95489.1 - 0.0011 18.6 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.20 KII95489.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF3089 PF11288.8 KII95489.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF818 PF05677.12 KII95489.1 - 0.02 13.9 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 KII95489.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 KII95489.1 - 0.038 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 KII95489.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 KII95489.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 KII95489.1 - 0.15 11.6 0.0 0.82 9.2 0.0 1.9 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 KII95489.1 - 0.15 11.8 0.1 0.69 9.7 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Pet100 PF09803.9 KII95490.1 - 0.0079 16.7 3.8 1.2 9.7 0.7 2.5 2 1 0 2 2 2 2 Pet100 Inhibitor_I10 PF12559.8 KII95490.1 - 0.027 14.7 0.2 0.72 10.1 0.1 2.3 2 0 0 2 2 2 0 Serine endopeptidase inhibitors Sacchrp_dh_NADP PF03435.18 KII95491.1 - 3.3e-18 66.2 0.1 6.3e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KII95491.1 - 5.2e-09 36.3 0.1 8.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KII95491.1 - 6.6e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KII95491.1 - 6.8e-06 26.5 0.0 3.6e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KII95491.1 - 2.6e-05 23.8 0.1 4.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII95491.1 - 3.3e-05 23.0 0.0 5.7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KII95491.1 - 0.00027 20.9 0.2 0.00072 19.5 0.2 1.7 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 KII95491.1 - 0.0031 17.6 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KII95491.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.16 KII95491.1 - 0.015 16.0 0.1 1.5 9.5 0.1 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Shikimate_DH PF01488.20 KII95491.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KII95491.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KII95493.1 - 1.3e-74 251.7 0.0 4.9e-74 249.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Sortase PF04203.13 KII95493.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Sortase domain HTH_55 PF18622.1 KII95494.1 - 0.031 14.6 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 RctB helix turn helix domain U1snRNP70_N PF12220.8 KII95494.1 - 0.048 14.3 1.4 0.15 12.7 0.9 1.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SAM_2 PF07647.17 KII95496.1 - 0.0049 17.0 0.0 0.035 14.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) BRE1 PF08647.11 KII95496.1 - 0.12 12.5 4.7 0.2 11.7 4.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FliJ PF02050.16 KII95496.1 - 0.22 11.8 5.7 0.38 11.0 5.7 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Ank_3 PF13606.6 KII95498.1 - 0.0055 17.1 0.0 0.051 14.1 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 KII95498.1 - 0.012 16.2 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-CHY PF05495.12 KII95499.1 - 2e-13 50.6 19.7 3.3e-13 49.9 19.7 1.4 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 KII95499.1 - 0.005 16.6 4.8 0.59 10.0 0.0 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR Zn-ribbon_8 PF09723.10 KII95499.1 - 0.06 13.5 5.0 0.06 13.5 5.0 2.6 1 1 2 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 KII95499.1 - 0.32 11.3 14.0 8.1 6.8 0.4 3.1 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 KII95499.1 - 0.47 10.4 10.6 0.17 11.8 0.8 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KII95499.1 - 0.61 10.1 12.7 7.3 6.6 0.1 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.19 KII95499.1 - 0.77 9.8 10.9 2.9 7.9 10.9 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DpnI PF06044.12 KII95499.1 - 0.82 9.3 5.2 1.1 8.9 3.1 1.9 1 1 0 1 1 1 0 Dam-replacing family zinc_ribbon_4 PF13717.6 KII95499.1 - 1.1 9.2 0.1 1.1 9.2 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Bac_rhodopsin PF01036.18 KII95500.1 - 5e-39 134.2 19.2 6.4e-39 133.8 19.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2157 PF09925.9 KII95500.1 - 1.2 9.0 14.5 0.096 12.5 9.6 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) 5_nucleotid_C PF02872.18 KII95502.1 - 0.0037 17.5 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain N2227 PF07942.12 KII95503.1 - 4.8e-65 219.5 0.0 6.4e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KII95503.1 - 0.013 16.2 0.0 0.086 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KII95503.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Clat_adaptor_s PF01217.20 KII95507.1 - 1.6e-17 63.7 0.0 2.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FCH PF00611.23 KII95508.1 - 5.6e-17 61.8 0.1 1.7e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KII95508.1 - 7.6e-10 38.2 0.1 1.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KII95508.1 - 1.9e-07 30.8 0.1 4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KII95508.1 - 0.0002 21.0 0.0 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Myb_DNA-binding PF00249.31 KII95509.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-X PF09415.10 KII95509.1 - 0.11 12.8 1.5 1 9.7 0.2 2.5 2 0 0 2 2 2 0 CENP-S associating Centromere protein X RRM_1 PF00076.22 KII95511.1 - 1.1e-28 98.8 2.2 8.3e-09 35.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII95511.1 - 0.0002 21.2 0.0 0.53 10.2 0.0 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KII95511.1 - 0.0003 20.4 0.0 0.032 13.8 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KII95511.1 - 0.017 15.1 7.4 0.76 9.9 0.1 3.1 3 0 0 3 3 3 0 RNA binding motif NID PF07292.13 KII95511.1 - 0.021 15.4 0.0 12 6.7 0.0 3.6 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 KII95511.1 - 0.072 13.2 0.1 1.4 9.1 0.0 3.0 4 0 0 4 4 4 0 RNA recognition motif TA0956 PF11513.8 KII95511.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 TFIIA PF03153.13 KII95511.1 - 0.53 10.2 14.6 0.045 13.7 5.3 2.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 KII95511.1 - 3.6 7.7 12.4 2.3 8.4 8.9 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KII95511.1 - 5.2 6.6 15.0 0.15 11.6 8.6 1.6 2 0 0 2 2 2 0 Spt20 family Sugar_tr PF00083.24 KII95512.1 - 8.1e-103 344.7 19.8 1e-102 344.4 19.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII95512.1 - 9.1e-22 77.4 41.7 1.2e-21 77.1 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII95512.1 - 4.8e-05 22.0 1.1 0.0001 20.9 1.1 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RANK_CRD_2 PF18278.1 KII95512.1 - 0.24 11.6 0.5 0.48 10.6 0.5 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Aldo_ket_red PF00248.21 KII95513.1 - 5.8e-48 163.6 0.2 2e-47 161.8 0.2 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KII95514.1 - 2.1e-05 24.3 0.2 0.00017 21.4 0.2 2.3 1 1 0 1 1 1 1 F-box-like DUF443 PF04276.12 KII95515.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF443) IKI3 PF04762.12 KII95516.1 - 1.9e-240 800.6 0.0 6.5e-186 620.2 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 KII95516.1 - 3.5e-06 27.2 0.3 0.14 12.5 0.0 5.4 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Copine PF07002.16 KII95516.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Copine DUF848 PF05852.11 KII95516.1 - 0.8 9.8 2.9 8.6 6.5 0.1 2.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) F-box-like PF12937.7 KII95517.1 - 3.4e-06 26.9 0.4 5.4e-05 23.0 0.4 2.5 1 1 0 1 1 1 1 F-box-like 7tm_6 PF02949.20 KII95517.1 - 0.093 11.8 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 7tm Odorant receptor BTB PF00651.31 KII95518.1 - 6.2e-05 23.2 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII95519.1 - 3.4e-07 30.5 0.0 6.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII95521.1 - 9.5e-07 29.0 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII95522.1 - 0.00059 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain polyprenyl_synt PF00348.17 KII95524.1 - 6e-44 150.0 0.0 9.3e-43 146.1 0.0 1.9 1 1 0 1 1 1 1 Polyprenyl synthetase BTB PF00651.31 KII95527.1 - 0.00072 19.8 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF3697 PF12478.8 KII95527.1 - 0.0034 17.5 1.5 21 5.3 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin-associated protein 2 F-box-like PF12937.7 KII95528.1 - 2e-05 24.4 0.0 6.2e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 F-box-like DUF4729 PF15866.5 KII95528.1 - 0.054 12.8 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) Efg1 PF10153.9 KII95529.1 - 8.9e-34 116.3 10.8 1.4e-33 115.6 10.8 1.3 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Fez1 PF06818.15 KII95529.1 - 0.0095 16.4 4.4 0.015 15.8 4.4 1.3 1 0 0 1 1 1 1 Fez1 23S_rRNA_IVP PF05635.11 KII95529.1 - 0.021 15.1 0.6 0.037 14.3 0.6 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein HTH_12 PF08461.10 KII95529.1 - 0.065 13.2 1.6 0.16 11.9 1.6 1.7 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain polyprenyl_synt PF00348.17 KII95530.1 - 5.3e-59 199.3 0.0 1.5e-58 197.9 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase F-box-like PF12937.7 KII95531.1 - 0.0022 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like BTB PF00651.31 KII95532.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain F-box-like PF12937.7 KII95534.1 - 8.1e-08 32.0 0.3 4.6e-07 29.6 0.3 2.3 1 1 0 1 1 1 1 F-box-like Ribosomal_S11 PF00411.19 KII95535.1 - 6.2e-07 29.8 0.5 2.3e-06 27.9 0.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S11 F-box-like PF12937.7 KII95537.1 - 0.00023 21.0 1.5 0.00049 19.9 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KII95537.1 - 0.0016 18.3 0.5 0.0053 16.6 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KII95537.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 F-box Sld7_C PF18596.1 KII95539.1 - 2e-06 27.8 0.2 3.7e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain F-box-like PF12937.7 KII95540.1 - 2.7e-06 27.1 0.9 9.7e-06 25.4 0.9 1.9 1 1 0 1 1 1 1 F-box-like Peptidase_S8 PF00082.22 KII95541.1 - 6.4e-32 111.0 13.4 1.2e-31 110.1 13.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KII95541.1 - 6.5e-13 49.2 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DSBA PF01323.20 KII95542.1 - 6.6e-28 97.8 0.0 7.9e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1525 PF07511.11 KII95542.1 - 0.0023 18.1 0.1 0.0045 17.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) Thioredoxin_3 PF13192.6 KII95542.1 - 0.022 14.8 0.0 1.1 9.3 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KII95542.1 - 0.025 14.8 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin Glyco_hydro_31 PF01055.26 KII95544.1 - 5.6e-138 460.8 5.1 5.6e-138 460.8 5.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KII95544.1 - 6.9e-19 67.9 0.2 7.5e-18 64.6 0.2 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KII95544.1 - 1.1e-06 28.8 0.0 3.7e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 KII95544.1 - 0.0031 17.7 0.5 0.0066 16.6 0.5 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region NAD_Gly3P_dh_N PF01210.23 KII95546.1 - 0.017 15.1 0.0 0.018 15.1 0.0 1.0 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KII95547.1 - 6.3e-50 169.5 0.9 5e-49 166.6 0.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KII95547.1 - 8.1e-32 109.7 0.0 1.6e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KII95547.1 - 0.0002 21.6 0.5 0.001 19.3 0.5 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KII95547.1 - 0.011 15.2 0.1 0.029 13.8 0.1 1.7 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KII95547.1 - 0.025 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sulfate_transp PF00916.20 KII95548.1 - 6.7e-90 301.6 17.7 6.7e-90 301.6 17.7 1.4 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KII95548.1 - 1.8e-17 63.0 0.0 4.6e-17 61.7 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KII95548.1 - 6e-05 23.3 0.2 0.00017 21.9 0.2 1.8 1 0 0 1 1 1 1 STAS domain AA_permease_2 PF13520.6 KII95549.1 - 7.7e-64 216.1 55.8 9.2e-64 215.8 55.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KII95549.1 - 1.3e-18 66.9 47.4 1.9e-18 66.3 47.4 1.2 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 KII95549.1 - 6.7 7.1 10.4 0.13 12.7 1.2 2.9 3 0 0 3 3 3 0 YlaH-like protein Helicase_C PF00271.31 KII95551.1 - 6.5e-18 65.1 0.0 4.7e-17 62.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII95551.1 - 1.3e-15 57.6 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KII95551.1 - 2.2e-10 40.8 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KII95551.1 - 0.02 15.2 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 KII95552.1 - 6.1e-23 81.8 0.0 9.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII95552.1 - 4.2e-11 42.3 0.0 8.2e-10 38.1 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KII95552.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 KII95553.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII95553.1 - 0.00034 20.6 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4692 PF15763.5 KII95553.1 - 0.052 14.0 2.8 0.085 13.3 2.8 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Choline_kinase PF01633.20 KII95553.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KII95553.1 - 0.22 11.1 0.3 0.39 10.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Macoilin PF09726.9 KII95553.1 - 1 7.8 4.7 1.2 7.6 4.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 KII95553.1 - 2 7.2 5.3 2.6 6.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SR-25 PF10500.9 KII95553.1 - 5.8 6.5 15.4 8.8 5.9 15.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 KII95553.1 - 6.6 3.7 8.5 8.1 3.4 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SNF2_N PF00176.23 KII95554.1 - 3.5e-64 216.7 0.3 5.7e-64 216.0 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KII95554.1 - 1e-17 64.5 0.0 9.4e-16 58.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KII95554.1 - 1.1e-09 38.5 0.0 2.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KII95554.1 - 0.004 16.9 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_12 PF13424.6 KII95554.1 - 0.16 12.3 1.0 0.5 10.7 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 KII95556.1 - 1.4e-69 234.4 0.0 1.7e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95556.1 - 3.9e-35 121.4 0.0 5.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KII95556.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 KII95557.1 - 0.0014 18.5 0.1 0.02 14.7 0.1 2.5 3 0 0 3 3 3 1 Homeodomain FSH1 PF03959.13 KII95558.1 - 2.8e-53 180.7 0.0 3.6e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KII95558.1 - 0.02 14.5 0.0 0.081 12.6 0.0 1.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold ACT_3 PF10000.9 KII95560.1 - 0.012 15.5 0.2 0.019 14.8 0.1 1.4 2 0 0 2 2 2 0 ACT domain COX14 PF14880.6 KII95560.1 - 0.02 14.7 4.2 0.033 14.0 4.2 1.6 1 1 0 1 1 1 0 Cytochrome oxidase c assembly Mito_carr PF00153.27 KII95561.1 - 4.6e-66 218.8 4.7 3.9e-23 81.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein eRF1_1 PF03463.15 KII95562.1 - 0.076 13.0 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 1 HEAT_EZ PF13513.6 KII95563.1 - 1.5e-28 98.8 19.6 2.3e-14 53.5 0.0 10.3 10 2 2 12 12 12 4 HEAT-like repeat HEAT PF02985.22 KII95563.1 - 1.3e-22 77.9 11.8 2.4e-05 24.2 0.0 10.1 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 KII95563.1 - 1.6e-14 54.0 0.0 3e-05 24.3 0.0 6.7 6 3 1 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KII95563.1 - 9.2e-09 35.8 0.0 0.014 15.9 0.1 3.6 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KII95563.1 - 8.6e-07 28.8 0.6 1.1 9.4 0.0 5.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KII95563.1 - 1.7e-06 28.2 0.0 0.098 12.7 0.0 4.2 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KII95563.1 - 6.1e-05 21.8 0.1 0.098 11.2 0.1 3.2 3 0 0 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 KII95563.1 - 6.4e-05 23.2 0.4 0.55 10.6 0.0 3.8 4 0 0 4 4 3 1 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.8 KII95563.1 - 0.00013 21.8 0.9 0.15 12.0 0.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) IBN_N PF03810.19 KII95563.1 - 0.0037 17.1 0.1 0.024 14.6 0.0 2.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Nipped-B_C PF12830.7 KII95563.1 - 0.037 14.0 0.0 16 5.4 0.0 3.8 3 1 0 4 4 4 0 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 KII95563.1 - 0.058 13.6 0.1 0.87 9.8 0.0 3.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 KII95563.1 - 0.077 12.5 0.2 26 4.2 0.1 3.5 2 2 1 3 3 3 0 Tti2 family RIX1 PF08167.12 KII95563.1 - 0.12 12.1 0.6 20 4.9 0.0 3.5 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Lectin_leg-like PF03388.13 KII95565.1 - 2.8e-64 216.6 0.1 3.6e-64 216.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KII95565.1 - 6.4e-06 25.9 0.0 0.0013 18.3 0.0 2.7 1 1 1 2 2 2 1 Legume lectin domain Pkinase_fungal PF17667.1 KII95566.1 - 4.5e-07 29.0 0.4 7.7e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 KII95566.1 - 1.6e-06 27.3 0.0 3e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 KII95566.1 - 7.6e-06 25.5 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KII95566.1 - 2.2e-05 23.9 0.1 3.5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KII95566.1 - 4.3e-05 23.6 0.4 8.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KII95566.1 - 9.6e-05 22.1 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KII95566.1 - 0.00011 21.6 0.0 0.00068 19.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KII95566.1 - 0.00014 21.5 0.2 0.00025 20.7 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KII95566.1 - 0.0031 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4135 PF13575.6 KII95566.1 - 0.13 11.5 0.4 0.29 10.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) Pkinase_fungal PF17667.1 KII95567.1 - 1.4e-05 24.1 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KII95567.1 - 2.7e-05 23.9 0.1 4.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KII95567.1 - 0.00028 20.3 0.0 0.00055 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KII95567.1 - 0.0027 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KII95567.1 - 0.005 16.2 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII95567.1 - 0.029 14.3 0.2 0.059 13.3 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIF4G PF02854.19 KII95568.1 - 6.5e-45 153.4 0.0 8.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain DUF445 PF04286.12 KII95568.1 - 0.0081 16.0 0.7 0.21 11.3 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF445) GRP PF07172.11 KII95568.1 - 0.16 12.6 14.5 0.41 11.4 14.5 1.6 1 0 0 1 1 1 0 Glycine rich protein family ER_lumen_recept PF00810.18 KII95569.1 - 8.1e-55 185.7 8.3 1.2e-54 185.1 8.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KII95569.1 - 0.0025 17.6 10.2 0.056 13.2 0.2 3.4 4 0 0 4 4 4 2 PQ loop repeat Pkinase_fungal PF17667.1 KII95570.1 - 1.3e-52 179.0 0.2 1.9e-52 178.4 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII95570.1 - 2.2e-05 24.0 0.0 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 KII95570.1 - 0.05 13.5 0.2 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family KASH_CCD PF14662.6 KII95571.1 - 0.00055 19.8 0.4 0.0014 18.5 0.4 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 KII95571.1 - 0.013 15.6 0.1 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 KII95571.1 - 0.032 14.5 7.6 0.048 13.9 0.5 3.3 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) PDE4_UCR PF18100.1 KII95571.1 - 0.037 14.7 0.0 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) ISG65-75 PF11727.8 KII95571.1 - 0.097 11.9 3.1 0.082 12.1 1.5 1.6 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF2390 PF09523.10 KII95571.1 - 0.2 12.0 2.2 0.49 10.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) DUF4203 PF13886.6 KII95572.1 - 2.2e-19 69.9 19.9 3.2e-19 69.4 19.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Cadherin_2 PF08266.12 KII95572.1 - 0.22 11.4 0.0 0.67 9.8 0.0 1.7 2 0 0 2 2 2 0 Cadherin-like Rit1_C PF17184.4 KII95573.1 - 4.4e-95 318.2 0.0 5.5e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KII95573.1 - 3.2e-27 95.0 0.0 7.9e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain Calpain_III PF01067.22 KII95574.1 - 3.8e-17 62.9 0.7 2.6e-07 31.0 0.3 3.5 2 1 0 2 2 2 2 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KII95574.1 - 3.2e-12 46.1 0.0 2e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease MIT PF04212.18 KII95574.1 - 7.6e-07 29.1 0.9 1.4e-06 28.2 0.9 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Evr1_Alr PF04777.13 KII95575.1 - 3.5e-28 98.0 0.7 4.8e-28 97.6 0.7 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF1970 PF09301.10 KII95575.1 - 0.028 14.7 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Kri1 PF05178.12 KII95576.1 - 7.1e-25 87.6 7.7 7.1e-25 87.6 7.7 6.3 4 2 2 6 6 6 1 KRI1-like family Kri1_C PF12936.7 KII95576.1 - 6.5e-23 80.7 0.0 6.5e-23 80.7 0.0 4.9 4 0 0 4 4 4 1 KRI1-like family C-terminal Pantoate_transf PF02548.15 KII95577.1 - 1.1e-100 336.4 0.3 1.3e-100 336.1 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KII95577.1 - 1e-08 34.9 1.2 2.2e-08 33.9 0.2 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Sacchrp_dh_C PF16653.5 KII95578.1 - 1.3e-63 215.6 0.0 1.8e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KII95578.1 - 1.2e-14 54.6 0.1 2.6e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KII95578.1 - 1e-10 42.1 0.0 9.2e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KII95578.1 - 5.9e-05 22.5 0.0 0.00042 19.7 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KII95578.1 - 0.0037 17.3 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.7 KII95580.1 - 1.3e-07 32.1 0.0 2.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KII95580.1 - 0.0077 16.0 0.0 0.016 15.0 0.0 1.5 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase tRNA-synt_2 PF00152.20 KII95581.1 - 4e-87 292.2 0.0 5.7e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KII95581.1 - 1.1e-11 44.5 0.1 2.8e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FMN_red PF03358.15 KII95581.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF4539 PF15072.6 KII95581.1 - 0.19 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) DUF3328 PF11807.8 KII95582.1 - 5.7e-50 170.1 0.7 7.3e-50 169.8 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cyclase_polyket PF04673.12 KII95582.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthesis cyclase CLLAC PF15675.5 KII95583.1 - 0.56 9.8 3.7 0.84 9.2 3.7 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain Acetyltransf_10 PF13673.7 KII95585.1 - 1.2e-08 35.0 0.0 2.8e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KII95585.1 - 6.4e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KII95585.1 - 1.7e-05 25.2 0.0 6.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KII95585.1 - 0.0016 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KII95585.1 - 0.17 12.0 0.0 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TP_methylase PF00590.20 KII95590.1 - 1.7e-20 73.9 0.0 2.7e-20 73.2 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases LSM PF01423.22 KII95592.1 - 4.2e-17 61.6 0.1 5.4e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII95592.1 - 0.19 11.9 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain SelK_SelG PF10961.8 KII95592.1 - 0.95 10.1 8.5 1.6 9.4 8.5 1.3 1 0 0 1 1 1 0 Selenoprotein SelK_SelG CFEM PF05730.11 KII95594.1 - 0.037 14.1 1.1 0.083 13.0 1.1 1.6 1 0 0 1 1 1 0 CFEM domain Orthopox_A5L PF06193.11 KII95595.1 - 0.041 13.3 0.9 0.057 12.8 0.9 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Glyco_hydro_28 PF00295.17 KII95596.1 - 2e-60 204.6 12.8 2.5e-60 204.2 12.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KII95596.1 - 4.2 7.2 23.8 0.089 12.6 15.7 2.2 1 1 1 2 2 2 0 Right handed beta helix region OPT PF03169.15 KII95597.1 - 7.9e-183 609.4 49.5 9e-183 609.2 49.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sec16_N PF12935.7 KII95598.1 - 0.033 14.4 2.5 0.06 13.5 2.5 1.4 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus zf-MYND PF01753.18 KII95600.1 - 2.5e-09 37.1 6.7 5.2e-09 36.0 6.7 1.5 1 0 0 1 1 1 1 MYND finger PKS_DE PF18369.1 KII95600.1 - 0.16 12.6 1.2 0.24 12.0 0.0 2.0 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain zf-C6H2 PF15801.5 KII95600.1 - 0.55 10.6 3.9 1.1 9.6 3.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding BTB PF00651.31 KII95602.1 - 2.7e-05 24.4 0.0 4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 KII95603.1 - 0.0065 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF5321 PF17254.2 KII95604.1 - 0.071 12.5 0.3 0.11 11.9 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5321) BTB PF00651.31 KII95605.1 - 2.2e-08 34.3 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DpnII PF04556.12 KII95606.1 - 0.068 12.5 0.1 0.072 12.4 0.1 1.0 1 0 0 1 1 1 0 DpnII restriction endonuclease BTB PF00651.31 KII95607.1 - 1.6e-07 31.5 0.0 2.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.9 KII95608.1 - 3.5e-42 144.2 0.0 6e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PGP_phosphatase PF09419.10 KII95610.1 - 9.7e-46 155.4 0.0 1.3e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KII95610.1 - 0.0066 16.5 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like GRDA PF04723.14 KII95610.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A alpha-hel2 PF14456.6 KII95611.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 ABC_membrane PF00664.23 KII95612.1 - 6e-51 173.7 1.0 8e-51 173.3 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KII95612.1 - 5.8e-31 107.8 0.0 1.6e-30 106.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KII95612.1 - 2.7e-05 23.7 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KII95612.1 - 0.0064 15.8 0.0 0.02 14.2 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 KII95612.1 - 0.074 13.1 0.5 0.15 12.1 0.2 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3294 PF07957.11 KII95613.1 - 0.0011 18.7 0.3 0.0021 17.9 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3294) PV-1 PF06637.11 KII95613.1 - 0.018 13.9 1.0 0.022 13.6 1.0 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) SipA PF09052.10 KII95613.1 - 0.055 13.1 1.6 0.086 12.4 1.6 1.3 1 0 0 1 1 1 0 SipA N-terminal domain SlyX PF04102.12 KII95613.1 - 0.11 13.1 9.6 0.082 13.5 4.8 2.9 3 0 0 3 3 3 0 SlyX LigT_PEase PF02834.16 KII95613.1 - 0.26 11.5 1.9 4.8 7.4 0.2 2.9 3 0 0 3 3 3 0 LigT like Phosphoesterase DUF4140 PF13600.6 KII95613.1 - 3.4 8.2 7.8 7.5 7.1 4.9 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HIP1_clath_bdg PF16515.5 KII95613.1 - 3.5 8.3 14.0 2.5 8.7 9.4 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FUSC PF04632.12 KII95613.1 - 4.9 5.6 5.8 6.5 5.2 5.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hydrolase_4 PF12146.8 KII95614.1 - 2.5e-54 184.1 0.0 2.9e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII95614.1 - 5.3e-15 56.6 0.3 6.4e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII95614.1 - 2.4e-10 40.5 0.8 9e-09 35.3 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KII95614.1 - 9.5e-07 27.8 0.2 0.0085 14.8 0.0 2.8 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KII95614.1 - 3.6e-05 23.3 0.3 0.0019 17.7 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 KII95614.1 - 0.00013 21.6 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 KII95614.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KII95614.1 - 0.0099 15.5 0.2 0.02 14.6 0.2 1.6 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KII95614.1 - 0.13 11.2 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Clathrin_lg_ch PF01086.17 KII95615.1 - 1.4e-42 146.4 1.8 1.6e-42 146.1 1.8 1.1 1 0 0 1 1 1 1 Clathrin light chain Peptidase_C37 PF05416.12 KII95615.1 - 0.091 11.3 1.6 0.12 10.9 1.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RsbRD_N PF14361.6 KII95615.1 - 0.3 11.8 2.7 0.52 11.0 2.7 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Ribosomal_L30_N PF08079.12 KII95615.1 - 0.75 10.1 11.8 1.5 9.1 11.8 1.5 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PTH2 PF01981.16 KII95616.1 - 1.8e-14 54.0 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SUR7 PF06687.12 KII95617.1 - 9.2e-13 48.3 19.4 1.3e-12 47.8 19.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KII95617.1 - 0.0078 16.0 3.8 0.0078 16.0 3.8 1.6 1 1 1 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2263 PF10021.9 KII95619.1 - 7.2e-64 214.6 2.6 1.3e-34 119.6 0.4 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) ubiquitin PF00240.23 KII95620.1 - 1.3e-07 31.2 0.2 6.3e-07 29.0 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KII95620.1 - 3.2e-06 27.5 0.2 1.4e-05 25.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 KII95620.1 - 0.016 15.0 0.1 0.12 12.3 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RAWUL PF16207.5 KII95620.1 - 0.017 15.8 0.0 0.02 15.5 0.0 1.1 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PI3K_rbd PF00794.18 KII95620.1 - 0.12 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Aa_trans PF01490.18 KII95622.1 - 1.1e-27 96.8 27.1 1.9e-27 96.1 27.1 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5515 PF17635.2 KII95622.1 - 0.12 13.1 0.1 0.29 11.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5515) SLATT_5 PF18160.1 KII95622.1 - 0.21 10.9 0.3 0.61 9.4 0.3 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Glyco_hydro_12 PF01670.16 KII95623.1 - 2.4e-43 148.6 15.0 2.8e-43 148.4 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF5560 PF17715.1 KII95623.1 - 0.0013 18.2 1.9 0.031 13.7 0.5 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5560) Foie-gras_1 PF11817.8 KII95624.1 - 8.2e-40 137.0 1.3 1.1e-37 130.1 0.9 2.9 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 KII95624.1 - 5.7e-15 55.1 0.0 6.5e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Gryzun, putative trafficking through Golgi TPR_1 PF00515.28 KII95624.1 - 0.0066 16.2 0.6 0.073 12.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII95624.1 - 0.013 15.3 0.1 0.087 12.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KII95624.1 - 0.033 14.2 0.9 0.32 11.1 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KII95624.1 - 0.042 14.1 0.0 0.042 14.1 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Gryzun-like PF12742.7 KII95624.1 - 0.05 13.6 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TPR_2 PF07719.17 KII95624.1 - 0.061 13.5 3.9 0.069 13.3 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KII95624.1 - 0.15 12.3 0.6 0.54 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC10 PF12584.8 KII95624.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_6 PF13174.6 KII95624.1 - 0.22 12.2 0.4 1.2 10.0 0.4 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat GST_N_3 PF13417.6 KII95625.1 - 3.2e-18 65.9 0.0 6.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KII95625.1 - 7e-16 58.3 0.0 2e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KII95625.1 - 2.2e-11 43.9 0.4 1.5e-10 41.2 0.2 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KII95625.1 - 1.5e-06 28.2 0.1 3.3e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KII95625.1 - 1.1e-05 25.5 0.1 2.3e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KII95625.1 - 0.0005 20.6 0.0 0.00085 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KII95625.1 - 0.086 13.6 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Abhydrolase_6 PF12697.7 KII95626.1 - 6.2e-10 40.1 0.2 8.1e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII95626.1 - 2.7e-07 30.5 0.1 1.1e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII95626.1 - 0.00016 21.0 0.1 0.00042 19.6 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KII95626.1 - 0.089 12.3 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KII95627.1 - 6.5e-40 137.2 0.0 1.3e-32 113.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KII95627.1 - 1.6e-09 37.1 0.0 2.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase SAGA-Tad1 PF12767.7 KII95627.1 - 0.057 13.1 0.4 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ATG_C PF09333.11 KII95629.1 - 0.0097 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain TMEM70 PF06979.12 KII95630.1 - 5.1e-06 26.9 0.2 6.5e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex Hexapep PF00132.24 KII95631.1 - 5.3e-11 41.8 20.3 7.5e-07 28.6 2.2 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KII95631.1 - 4.5e-08 32.7 11.8 5.6e-05 22.8 0.6 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KII95631.1 - 4.5e-05 22.6 0.0 6.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase APH PF01636.23 KII95633.1 - 1.2e-37 130.1 0.0 1.7e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KII95633.1 - 9.2e-06 25.4 0.0 7.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KII95633.1 - 0.0056 16.0 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase HSP70 PF00012.20 KII95634.1 - 3.3e-262 871.0 15.5 3.9e-262 870.8 15.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KII95634.1 - 6e-14 51.6 6.9 1.4e-12 47.1 0.7 3.2 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 KII95634.1 - 0.037 13.8 0.0 0.098 12.4 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KII95634.1 - 0.048 14.1 8.0 2.5 8.6 0.1 4.0 3 2 0 3 3 3 0 Cell division protein FtsA FMN_dh PF01070.18 KII95635.1 - 9.4e-118 393.2 0.1 1.1e-117 393.0 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KII95635.1 - 2.8e-20 72.2 0.0 5.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KII95635.1 - 0.0001 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KII95635.1 - 0.0017 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.6 KII95636.1 - 1.6e-45 155.4 2.7 2.3e-45 154.9 2.7 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KII95636.1 - 2.1e-18 66.1 0.3 2.9e-18 65.6 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 KII95636.1 - 0.02 14.2 0.1 0.058 12.6 0.1 1.8 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like F-box PF00646.33 KII95637.1 - 0.0055 16.6 0.8 0.02 14.7 0.7 2.2 1 1 0 1 1 1 1 F-box domain LCM PF04072.14 KII95638.1 - 2.6e-21 76.4 0.0 4.7e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MIF4G PF02854.19 KII95639.1 - 1.3e-55 188.3 0.1 2.6e-55 187.3 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KII95639.1 - 2.5e-18 66.0 0.0 8e-18 64.4 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 KII95639.1 - 0.00021 21.3 0.0 0.0007 19.6 0.0 1.9 1 0 0 1 1 1 1 MA3 domain Claudin_2 PF13903.6 KII95640.1 - 0.011 15.5 3.1 1 9.1 3.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3686 PF12458.8 KII95640.1 - 0.055 12.0 0.0 0.078 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair Arrestin_C PF02752.22 KII95641.1 - 1.1e-14 55.0 0.0 1e-13 51.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KII95641.1 - 2.9e-11 43.6 0.0 6.2e-08 32.8 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KII95641.1 - 0.025 14.3 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Arrestin_N terminal like Tim17 PF02466.19 KII95642.1 - 3.1e-32 111.2 10.1 4e-32 110.9 10.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KII95642.1 - 0.038 14.0 3.2 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) TrkH PF02386.16 KII95643.1 - 2.4e-109 366.1 5.9 3.7e-106 355.6 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.11 KII95643.1 - 0.5 10.4 2.7 0.68 9.9 0.2 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Amidohydro_1 PF01979.20 KII95644.1 - 2.4e-23 83.0 0.0 9.9e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KII95644.1 - 7e-12 45.6 0.1 4.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family F-box-like PF12937.7 KII95645.1 - 2e-05 24.4 0.2 3.7e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like Transketolase_N PF00456.21 KII95646.1 - 7.6e-126 419.6 0.0 1e-125 419.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KII95646.1 - 4.8e-37 127.3 0.0 8.6e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KII95646.1 - 2.8e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KII95646.1 - 1.3e-06 27.8 0.0 1.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KII95646.1 - 7.7e-05 22.5 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1985 PF09331.11 KII95646.1 - 0.11 12.5 0.0 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) F-box-like PF12937.7 KII95647.1 - 1.8e-07 30.9 3.0 1.8e-07 30.9 1.1 2.2 2 0 0 2 2 2 1 F-box-like Fungal_trans PF04082.18 KII95648.1 - 2.1e-27 95.9 0.0 3.5e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII95648.1 - 9.7e-05 22.4 7.4 0.00021 21.3 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KII95648.1 - 0.2 11.4 3.4 0.42 10.4 3.4 1.6 1 0 0 1 1 1 0 Integrin plexin domain CBM_1 PF00734.18 KII95650.1 - 1.6e-12 47.1 12.2 4.6e-12 45.7 12.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain AXE1 PF05448.12 KII95650.1 - 0.2 10.3 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Rer1 PF03248.13 KII95651.1 - 2.7e-69 232.3 0.0 3.1e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 KII95651.1 - 0.13 11.9 1.0 0.21 11.2 1.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF3093 PF11292.8 KII95651.1 - 2.1 8.6 7.2 2.1 8.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) MFS_1 PF07690.16 KII95652.1 - 3.4e-25 88.7 30.5 3.4e-25 88.7 30.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.23 KII95653.1 - 3.2e-11 43.1 0.1 4.6e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KII95653.1 - 3.1e-06 27.7 1.4 4.5e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin SSTK-IP PF15836.5 KII95653.1 - 0.32 11.1 2.0 3.7 7.7 0.1 2.5 2 1 0 2 2 2 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Polysacc_lyase PF14099.6 KII95657.1 - 0.0019 18.1 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase AAA_16 PF13191.6 KII95658.1 - 2e-06 28.3 0.4 5.6e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KII95658.1 - 0.078 12.7 0.3 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-CCCH_2 PF14608.6 KII95659.1 - 5.4e-12 45.7 36.0 3.2e-05 24.2 2.7 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger End3 PF12761.7 KII95659.1 - 0.17 12.0 0.8 0.3 11.2 0.8 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 FUSC PF04632.12 KII95660.1 - 3.3 6.1 10.0 0.077 11.5 2.4 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family UPF0029 PF01205.19 KII95661.1 - 5.5e-27 94.2 0.0 1.2e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 HEPN_AbiU2 PF18734.1 KII95661.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 AbiU2 RP-C_C PF11800.8 KII95661.1 - 0.088 12.9 2.8 0.082 13.0 1.6 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region AMP-binding_C PF13193.6 KII95662.1 - 0.068 14.2 0.0 0.15 13.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_72 PF03198.14 KII95663.1 - 1.7e-110 369.2 0.1 2.1e-110 368.9 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KII95663.1 - 2.4e-18 66.6 0.8 2.4e-18 66.6 0.8 2.4 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 KII95663.1 - 0.0041 16.6 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FLILHELTA PF10306.9 KII95664.1 - 2.2e-09 37.6 0.0 3.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KII95664.1 - 0.0039 17.7 0.0 0.0062 17.1 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MerR-DNA-bind PF09278.11 KII95665.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 MerR, DNA binding CTP_transf_like PF01467.26 KII95666.1 - 2.2e-23 83.0 0.0 2.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like bZIP_1 PF00170.21 KII95667.1 - 3.6e-09 36.6 9.2 8.1e-09 35.5 9.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII95667.1 - 5.6e-06 26.3 11.1 5.6e-06 26.3 11.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper ABC_tran_CTD PF16326.5 KII95667.1 - 0.00089 19.5 6.2 0.0087 16.3 1.1 2.3 2 0 0 2 2 2 2 ABC transporter C-terminal domain DivIC PF04977.15 KII95667.1 - 0.34 10.7 7.3 1.9 8.3 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 KII95667.1 - 0.85 10.1 5.3 1.5 9.4 5.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Csm1_N PF18504.1 KII95667.1 - 1.2 9.6 3.6 8.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Acyl-CoA_dh_N PF02771.16 KII95669.1 - 8.4e-29 100.5 0.0 1.4e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KII95669.1 - 2.8e-26 92.5 0.1 4.1e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII95669.1 - 9.2e-21 73.9 0.0 2e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KII95669.1 - 1.4e-05 25.4 0.2 2.9e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KII95669.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DNA_pol_B_thumb PF14791.6 KII95670.1 - 1.3e-21 76.5 0.0 2.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KII95670.1 - 3.4e-19 69.1 0.1 7.5e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KII95670.1 - 1.1e-09 38.0 0.0 5.4e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KII95670.1 - 1.8e-08 34.6 0.0 1.9e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KII95670.1 - 3.3e-06 27.6 0.0 0.00026 21.5 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KII95670.1 - 0.00029 21.0 0.0 0.00076 19.7 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus DUF4692 PF15763.5 KII95671.1 - 0.057 13.9 0.5 0.092 13.2 0.5 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Saf_2TM PF18303.1 KII95672.1 - 0.032 13.8 0.3 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain RR_TM4-6 PF06459.12 KII95672.1 - 0.24 11.2 0.0 0.39 10.5 0.0 1.5 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 ADH_N PF08240.12 KII95677.1 - 1.2e-27 96.0 0.2 1.9e-27 95.3 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII95677.1 - 6.3e-16 58.5 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII95677.1 - 9.7e-06 25.2 1.4 0.00052 19.6 1.4 2.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII95677.1 - 0.00028 21.9 0.0 0.00054 21.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.6 KII95677.1 - 0.0079 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KII95677.1 - 0.016 14.5 0.4 0.022 14.0 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KII95677.1 - 0.047 13.0 1.3 0.062 12.6 1.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NCD3G PF07562.14 KII95677.1 - 0.053 13.5 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR FAD_binding_2 PF00890.24 KII95677.1 - 0.084 11.9 1.1 0.12 11.4 1.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KII95677.1 - 0.1 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KII95677.1 - 0.18 11.1 0.4 0.3 10.4 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KII95678.1 - 5.5e-101 338.7 20.1 6.2e-101 338.5 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII95678.1 - 1.1e-20 73.9 23.8 1.1e-20 73.9 23.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KII95678.1 - 0.039 12.4 5.4 0.01 14.3 2.4 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) LRR_4 PF12799.7 KII95679.1 - 0.14 12.6 4.3 5.2 7.6 0.4 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII95680.1 - 0.053 13.4 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 F-box-like Steroid_dh PF02544.16 KII95682.1 - 1.6e-27 96.3 0.3 1.6e-27 96.3 0.3 1.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KII95682.1 - 3e-05 23.7 0.3 5e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.22 KII95683.1 - 1e-70 238.8 0.0 1.2e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 KII95684.1 - 4.2e-155 516.6 0.0 4.9e-155 516.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DIOX_N PF14226.6 KII95685.1 - 1.6e-28 99.8 0.0 2.5e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KII95685.1 - 3.6e-19 69.1 0.0 1.2e-18 67.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RSN1_7TM PF02714.15 KII95686.1 - 5.2e-78 262.1 27.4 9.5e-78 261.3 27.4 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KII95686.1 - 1.2e-38 133.0 0.0 1.9e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KII95686.1 - 1e-35 122.8 2.7 1e-35 122.8 2.7 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Fungal_trans PF04082.18 KII95687.1 - 1.8e-15 56.7 0.0 2.9e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII95687.1 - 0.00012 22.1 6.5 0.0002 21.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallothio_6 PF05522.11 KII95687.1 - 0.28 11.7 4.5 0.51 10.9 4.5 1.3 1 0 0 1 1 1 0 Metallothionein Abhydrolase_3 PF07859.13 KII95688.1 - 1.1e-62 211.7 0.0 1.3e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KII95688.1 - 1.4e-11 43.9 0.0 3.7e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KII95688.1 - 7.4e-06 26.7 1.4 7.4e-06 26.7 1.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KII95688.1 - 0.00022 20.8 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KII95688.1 - 0.0056 15.6 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 KII95688.1 - 0.029 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase PF07224.11 KII95688.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase_phd PF10503.9 KII95688.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Isochorismatase PF00857.20 KII95689.1 - 1.2e-28 100.5 0.0 1.4e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Get5_C PF18514.1 KII95689.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Get5 C-terminal domain MFS_1 PF07690.16 KII95690.1 - 4.8e-44 150.7 27.3 4.8e-44 150.7 27.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KII95690.1 - 3.6e-11 42.6 10.3 3.6e-11 42.6 10.3 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KII95690.1 - 7.7e-07 27.9 4.3 1.2e-06 27.3 4.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KII95690.1 - 0.0015 17.0 4.8 0.0015 17.0 4.8 2.2 3 0 0 3 3 3 1 Transmembrane secretion effector DUF5325 PF17259.2 KII95690.1 - 8.8 6.3 9.4 19 5.2 0.3 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Transp_cyt_pur PF02133.15 KII95691.1 - 8.1e-32 110.6 34.3 1.3e-30 106.6 34.3 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fcf1 PF04900.12 KII95694.1 - 1.7e-38 131.0 2.3 3.1e-38 130.1 2.3 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KII95694.1 - 3e-11 43.7 0.1 8.4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 PIN like domain Imm-NTF2 PF15655.6 KII95694.1 - 0.1 12.9 0.4 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 NTF2 fold immunity protein Lyase_aromatic PF00221.19 KII95696.1 - 1.4e-149 498.7 6.6 1.9e-149 498.3 6.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Cadherin_4 PF17803.1 KII95696.1 - 0.079 13.6 4.4 0.72 10.5 1.6 2.7 2 0 0 2 2 2 0 Bacterial cadherin-like domain F-box-like PF12937.7 KII95697.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like DAO PF01266.24 KII95698.1 - 4.5e-40 138.3 2.5 5.2e-40 138.1 2.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII95698.1 - 1.7e-05 24.8 0.1 0.021 14.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KII95698.1 - 1.7e-05 24.2 0.2 0.02 14.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KII95698.1 - 4.7e-05 22.9 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KII95698.1 - 0.00018 21.6 0.0 0.00042 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KII95698.1 - 0.0002 20.6 0.2 1.9 7.5 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.20 KII95698.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 KII95698.1 - 0.00097 18.1 0.1 0.0068 15.3 0.1 2.0 1 1 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 KII95698.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KII95698.1 - 0.022 14.0 0.0 0.066 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII95698.1 - 0.039 13.0 0.0 4.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.21 KII95698.1 - 0.045 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 KII95698.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 KII95698.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Glu_dehyd_C PF16912.5 KII95698.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 KII95698.1 - 0.093 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KII95698.1 - 0.1 11.8 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KII95698.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain CPSase_L_D2 PF02786.17 KII95699.1 - 1.8e-104 347.8 0.0 2.3e-81 272.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KII95699.1 - 1.2e-39 135.5 0.4 2.6e-39 134.3 0.4 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KII95699.1 - 6.5e-15 55.1 0.0 3.5e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KII95699.1 - 6.5e-11 42.1 0.0 6.1e-05 22.6 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KII95699.1 - 6.7e-10 38.8 0.0 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KII95699.1 - 0.00022 20.8 0.1 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KII95699.1 - 0.001 19.2 0.0 0.055 13.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain KGG PF10685.9 KII95699.1 - 0.022 15.0 0.3 0.23 11.8 0.0 2.6 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Peptidase_M17_N PF02789.17 KII95699.1 - 0.12 12.2 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain RNase_T PF00929.24 KII95701.1 - 2.2e-30 106.3 0.0 2.6e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KII95701.1 - 0.00073 19.6 0.0 0.00096 19.2 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like SWIB PF02201.18 KII95702.1 - 3e-29 100.7 0.2 5.2e-29 100.0 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KII95702.1 - 0.0014 18.5 0.1 0.011 15.7 0.1 2.4 2 1 0 2 2 2 1 DEK C terminal domain SRP-alpha_N PF04086.13 KII95702.1 - 0.93 9.4 12.1 1.3 8.9 12.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sel1 PF08238.12 KII95703.1 - 4.9e-26 90.6 31.1 5.4e-05 23.7 0.1 9.8 9 2 0 9 9 9 6 Sel1 repeat TPR_16 PF13432.6 KII95703.1 - 0.0009 19.8 9.1 0.084 13.5 0.1 5.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KII95703.1 - 0.016 15.8 3.1 5 8.0 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KII95703.1 - 0.22 11.7 0.1 0.22 11.7 0.1 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII95703.1 - 0.48 11.4 5.0 4.2 8.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KII95703.1 - 0.7 9.8 12.6 0.63 10.0 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat MIT PF04212.18 KII95703.1 - 0.81 9.8 2.5 10 6.3 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KII95703.1 - 2.4 8.2 9.7 0.22 11.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_4 PF13637.6 KII95704.1 - 0.00034 21.1 1.3 0.17 12.5 0.1 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) SAP PF02037.27 KII95704.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 SAP domain SnoaL_2 PF12680.7 KII95704.1 - 0.46 11.1 3.8 33 5.2 0.1 3.6 2 1 1 4 4 4 0 SnoaL-like domain Lactamase_B_3 PF13483.6 KII95705.1 - 3.1e-08 33.7 0.0 4.8e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KII95705.1 - 1.4e-06 28.0 0.1 2.4e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NRho PF16733.5 KII95706.1 - 0.14 12.3 0.3 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 Rhomboid N-terminal domain BRF1 PF07741.13 KII95706.1 - 4.8 7.6 6.0 3.4 8.1 0.5 2.5 3 0 0 3 3 3 0 Brf1-like TBP-binding domain F-box-like PF12937.7 KII95707.1 - 0.071 13.0 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like TauD PF02668.16 KII95708.1 - 1.9e-41 142.7 0.1 2.7e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lactamase_B PF00753.27 KII95709.1 - 1.8e-09 37.9 0.1 2.8e-09 37.3 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KII95709.1 - 7.5e-05 22.3 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KII95709.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Sugar_tr PF00083.24 KII95710.1 - 5.2e-116 388.2 30.8 5.9e-116 388.0 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII95710.1 - 3e-24 85.6 43.0 3e-24 85.6 43.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Deltameth_res PF16020.5 KII95710.1 - 1.4 8.8 6.3 1.1 9.2 1.5 3.0 2 0 0 2 2 2 0 Deltamethrin resistance TauD PF02668.16 KII95711.1 - 4.9e-46 157.7 0.5 6.5e-46 157.3 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family EarP PF10093.9 KII95712.1 - 0.017 14.2 0.3 0.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Elongation-Factor P (EF-P) rhamnosyltransferase EarP GTP-bdg_M PF16360.5 KII95712.1 - 0.076 13.6 3.7 10 6.8 1.4 3.3 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region 2-Hacid_dh_C PF02826.19 KII95713.1 - 7.3e-50 168.8 0.0 1.1e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII95713.1 - 3.5e-16 59.1 0.0 5.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII95713.1 - 0.0018 18.4 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_49 PF13896.6 KII95714.1 - 4.5e-68 230.0 4.9 2.7e-54 184.7 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 KII95714.1 - 0.084 13.4 0.3 0.78 10.3 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 2-Hacid_dh_C PF02826.19 KII95715.1 - 1.8e-48 164.3 0.0 4e-48 163.1 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KII95715.1 - 9.4e-17 60.9 0.0 1.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KII95715.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 KII95716.1 - 8.6e-37 126.9 28.5 8.6e-37 126.9 28.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.18 KII95718.1 - 0.00026 21.2 0.2 0.00099 19.3 0.2 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KII95718.1 - 0.063 13.1 0.1 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Barwin family F-box-like PF12937.7 KII95720.1 - 4.4e-06 26.5 0.5 7.1e-05 22.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KII95720.1 - 0.31 11.5 4.6 2.5 8.6 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KII95721.1 - 5.1e-05 23.1 0.1 0.00021 21.1 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII95721.1 - 0.049 14.1 11.0 0.2 12.2 0.2 5.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII95721.1 - 0.051 13.4 0.1 7.4 6.4 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat VWA_CoxE PF05762.14 KII95721.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Cornichon PF03311.14 KII95722.1 - 3.7e-52 175.8 8.0 4.3e-52 175.6 8.0 1.0 1 0 0 1 1 1 1 Cornichon protein RRM_1 PF00076.22 KII95723.1 - 0.0022 17.7 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 KII95724.1 - 0.0031 17.4 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like DPBB_1 PF03330.18 KII95727.1 - 4.5e-06 26.8 0.2 1.9e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KII95727.1 - 0.052 13.4 0.1 0.096 12.5 0.1 1.4 1 1 0 1 1 1 0 Barwin family COX2-transmemb PF09125.10 KII95727.1 - 0.41 10.5 1.8 0.69 9.7 1.8 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane MWFE PF15879.5 KII95728.1 - 0.14 12.4 2.2 12 6.1 1.6 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit PBP_N PF17093.5 KII95728.1 - 0.15 12.3 0.8 0.45 10.8 0.2 1.9 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus F-box-like PF12937.7 KII95729.1 - 4e-05 23.4 0.4 0.00017 21.4 0.4 2.1 1 0 0 1 1 1 1 F-box-like DUF563 PF04577.14 KII95730.1 - 6.2e-19 69.0 0.0 6.2e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF563) MA3 PF02847.17 KII95730.1 - 0.082 12.9 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 MA3 domain zf-C2H2 PF00096.26 KII95731.1 - 3.2e-27 93.4 71.1 0.00098 19.5 0.4 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII95731.1 - 1e-18 66.4 66.3 0.019 15.7 1.5 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KII95731.1 - 5.1e-13 48.8 77.5 2.3e-06 27.8 0.9 12.2 12 1 1 13 13 13 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 KII95731.1 - 1.9e-09 37.7 29.0 0.00039 20.7 4.9 6.1 3 2 4 7 7 7 3 C2H2-type zinc ribbon zf-met PF12874.7 KII95731.1 - 0.016 15.6 8.2 2.6 8.6 1.7 5.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KII95731.1 - 0.06 13.7 26.3 11 6.4 0.0 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding PcF PF09461.10 KII95731.1 - 0.55 10.6 11.3 8 6.9 1.9 4.7 4 1 1 5 5 5 0 Phytotoxin PcF protein CHORD PF04968.12 KII95731.1 - 1.4 9.7 39.2 12 6.7 3.5 6.0 4 1 1 5 5 5 0 CHORD zf-C2H2_6 PF13912.6 KII95731.1 - 1.9 8.6 42.7 0.38 10.8 0.6 8.3 9 0 0 9 9 9 0 C2H2-type zinc finger zf_ZIC PF18366.1 KII95731.1 - 5.5 7.2 17.8 5.7 7.1 0.0 5.4 6 1 0 6 6 6 0 Zic proteins zinc finger domain PAM2 PF07145.15 KII95732.1 - 0.0009 18.8 3.2 1.3 8.9 0.0 3.5 3 0 0 3 3 3 2 Ataxin-2 C-terminal region F-box-like PF12937.7 KII95733.1 - 1.1e-05 25.2 0.1 4.2e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KII95733.1 - 3 8.4 8.0 1.2e+02 3.3 0.0 5.4 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 KII95734.1 - 7.9e-31 107.2 68.9 5.4e-26 91.4 35.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII95734.1 - 1.2e-05 24.4 25.2 2.4e-05 23.4 25.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter LPD23 PF18838.1 KII95735.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 PhoLip_ATPase_C PF16212.5 KII95736.1 - 2.9e-78 263.1 21.7 2.9e-78 263.1 21.7 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KII95736.1 - 1.1e-25 89.1 4.4 3.8e-25 87.3 4.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KII95736.1 - 5.2e-12 45.7 0.0 2.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KII95736.1 - 3.2e-11 43.9 2.3 2.5e-06 27.9 0.5 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KII95736.1 - 9.4e-08 31.8 0.0 3e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KII95736.1 - 0.0022 17.8 0.1 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 KII95737.1 - 0.0003 19.7 0.0 0.00062 18.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KII95737.1 - 0.00037 20.2 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KII95737.1 - 0.0022 17.4 0.2 0.0034 16.7 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KII95737.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF4135 PF13575.6 KII95737.1 - 0.089 12.1 0.1 0.18 11.1 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) RIO1 PF01163.22 KII95737.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Trp_halogenase PF04820.14 KII95738.1 - 1.6e-25 89.9 6.2 4.5e-15 55.5 0.1 4.1 4 1 0 4 4 4 3 Tryptophan halogenase FAD_binding_3 PF01494.19 KII95738.1 - 3.7e-11 42.9 0.0 8.7e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KII95738.1 - 2.7e-06 27.5 0.2 1.1e-05 25.6 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KII95738.1 - 4.2e-06 26.4 0.8 9.1e-06 25.3 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KII95738.1 - 5.4e-06 25.7 0.6 1.5e-05 24.2 0.6 1.8 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KII95738.1 - 8.4e-06 25.6 1.2 0.00037 20.2 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KII95738.1 - 2.1e-05 23.5 0.2 3.3e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KII95738.1 - 3e-05 23.4 0.4 9.2e-05 21.8 0.2 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KII95738.1 - 4.3e-05 22.8 0.1 6.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KII95738.1 - 0.0013 19.2 0.1 0.05 14.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KII95738.1 - 0.0026 17.0 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KII95738.1 - 0.0039 16.3 0.9 0.0072 15.4 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KII95738.1 - 0.012 14.9 0.1 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KII95738.1 - 0.013 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase G-patch PF01585.23 KII95740.1 - 3.5e-07 30.0 2.3 5.5e-07 29.4 0.3 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KII95740.1 - 0.00016 21.6 0.6 0.00016 21.6 0.6 4.1 5 1 0 5 5 5 1 G-patch domain ThiJ_like PF17124.5 KII95741.1 - 1.1e-56 191.6 0.0 1.4e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KII95741.1 - 4.9e-09 36.2 0.0 2.7e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family PB1 PF00564.24 KII95742.1 - 2.5e-16 59.3 0.0 8.8e-16 57.6 0.0 1.9 2 0 0 2 2 2 1 PB1 domain TPR_1 PF00515.28 KII95742.1 - 1.9e-10 40.1 12.5 0.00037 20.2 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII95742.1 - 1.4e-08 34.2 15.5 0.041 14.0 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KII95742.1 - 3.2e-08 33.7 5.5 6.3e-05 23.2 1.4 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII95742.1 - 3.6e-08 33.0 9.0 0.00013 21.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KII95742.1 - 0.00035 20.2 0.1 0.00035 20.2 0.1 3.2 4 0 0 4 4 4 1 TPR repeat TPR_7 PF13176.6 KII95742.1 - 0.014 15.4 9.9 0.055 13.5 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KII95742.1 - 0.2 11.8 3.0 7.2 6.8 0.0 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KII95742.1 - 0.54 10.2 0.0 0.54 10.2 0.0 4.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KII95742.1 - 0.75 10.5 10.8 1 10.0 0.7 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII95742.1 - 2 9.4 8.1 25 6.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KII95742.1 - 5.5 7.8 8.2 1.4e+02 3.4 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat IGPS PF00218.21 KII95743.1 - 1.5e-91 306.1 0.0 2.6e-91 305.3 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KII95743.1 - 2.9e-44 151.1 0.0 4.6e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KII95743.1 - 3.5e-42 144.4 0.0 6.1e-37 127.3 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KII95743.1 - 2.5e-06 27.4 0.0 6.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KII95743.1 - 0.0013 18.6 0.2 0.049 13.4 0.0 2.8 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KII95743.1 - 0.097 12.1 0.1 0.31 10.5 0.1 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 KII95743.1 - 0.2 11.0 0.6 20 4.5 0.1 2.8 3 0 0 3 3 3 0 Thiamine monophosphate synthase FMN_dh PF01070.18 KII95743.1 - 0.21 10.6 4.7 0.31 10.0 1.8 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pkinase PF00069.25 KII95744.1 - 1.1e-66 224.9 0.0 1.4e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95744.1 - 4.2e-29 101.6 0.0 5.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 KII95744.1 - 0.016 16.1 0.0 0.041 14.8 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Haspin_kinase PF12330.8 KII95744.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KII95744.1 - 0.045 13.7 0.2 0.18 11.7 0.1 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KII95744.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.21 KII95745.1 - 6.2e-49 166.8 0.0 8.8e-41 140.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PH PF00169.29 KII95746.1 - 3.4e-05 24.3 0.0 0.00011 22.6 0.0 2.0 1 0 0 1 1 1 1 PH domain BRCT PF00533.26 KII95747.1 - 0.069 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 KII95748.1 - 2e-14 53.6 0.0 2.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KII95748.1 - 3.1e-07 30.6 0.0 5.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KII95748.1 - 1.2e-06 28.1 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KII95748.1 - 1.5e-06 27.7 0.0 2.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KII95748.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KII95748.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KII95748.1 - 0.017 13.9 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KII95748.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 KII95748.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FeoB_Cyto PF17910.1 KII95749.1 - 0.03 14.9 0.5 0.059 13.9 0.5 1.5 1 0 0 1 1 1 0 FeoB cytosolic helical domain DUF826 PF05696.11 KII95749.1 - 0.41 10.8 3.4 6.4 6.9 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF826) XPG_I_2 PF12813.7 KII95750.1 - 0.00023 20.7 0.0 0.0053 16.3 0.0 2.2 2 0 0 2 2 2 1 XPG domain containing SBE2 PF17076.5 KII95750.1 - 0.16 10.1 0.2 0.25 9.5 0.2 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation AlaE PF06610.13 KII95751.1 - 0.12 12.4 0.1 0.3 11.1 0.0 1.5 1 1 1 2 2 2 0 L-alanine exporter NAD_kinase PF01513.21 KII95752.1 - 2e-59 201.2 0.0 2.5e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KII95752.1 - 0.045 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase_fungal PF17667.1 KII95753.1 - 9.4e-58 195.9 0.1 2.3e-56 191.4 0.1 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KII95753.1 - 0.00026 20.5 0.0 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95753.1 - 0.09 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Hemerythrin PF01814.23 KII95761.1 - 9.8e-10 39.2 0.4 1.4e-09 38.7 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Phage_RpbA PF10789.9 KII95761.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA 3Beta_HSD PF01073.19 KII95762.1 - 9e-08 31.5 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KII95762.1 - 4.8e-05 22.9 0.0 0.0004 19.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KII95762.1 - 0.0023 17.1 0.0 0.033 13.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KII95762.1 - 0.012 15.6 0.4 0.028 14.3 0.2 1.8 2 1 0 2 2 2 0 NAD(P)H-binding AMP-binding PF00501.28 KII95763.1 - 8.8e-93 311.2 0.0 1.2e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KII95763.1 - 2.7e-10 41.1 1.0 2.7e-10 41.1 1.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AA_permease PF00324.21 KII95767.1 - 3.8e-139 464.4 40.3 4.4e-139 464.1 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KII95767.1 - 3.6e-38 131.5 50.2 4.7e-38 131.1 49.1 1.6 1 1 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KII95767.1 - 2.9 6.6 5.2 2.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Abhydrolase_6 PF12697.7 KII95769.1 - 3.8e-10 40.8 0.1 5.7e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII95769.1 - 3.6e-05 23.2 0.1 7.7e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KII95769.1 - 6.9e-05 22.6 0.2 0.00015 21.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold GIT_SHD PF08518.11 KII95770.1 - 1e-25 89.0 7.8 6.2e-13 48.1 3.0 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 KII95770.1 - 0.035 14.2 1.6 0.091 12.9 0.4 2.4 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term BLOC1_2 PF10046.9 KII95770.1 - 2.2 8.6 8.4 3.4 8.0 0.5 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA PF00004.29 KII95771.1 - 1.2e-30 106.6 0.0 2.3e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KII95771.1 - 6.4e-09 36.2 0.1 1.6e-07 31.7 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KII95771.1 - 6.4e-08 33.2 0.2 4e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KII95771.1 - 5.4e-06 27.0 0.0 1.5e-05 25.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KII95771.1 - 6e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KII95771.1 - 8.9e-05 22.5 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KII95771.1 - 0.00024 20.8 0.3 0.29 10.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KII95771.1 - 0.00024 20.4 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KII95771.1 - 0.00024 21.1 0.1 0.22 11.4 0.1 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KII95771.1 - 0.00026 21.2 0.1 0.00096 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KII95771.1 - 0.00049 19.4 0.1 0.11 11.7 0.0 2.7 2 1 0 3 3 3 1 KAP family P-loop domain AAA_24 PF13479.6 KII95771.1 - 0.00049 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KII95771.1 - 0.00065 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Viral_helicase1 PF01443.18 KII95771.1 - 0.00083 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KII95771.1 - 0.0017 18.6 0.0 0.006 16.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 KII95771.1 - 0.0018 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KII95771.1 - 0.0021 17.9 0.1 0.0061 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KII95771.1 - 0.003 17.5 0.0 0.0085 16.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 KII95771.1 - 0.0032 17.2 0.0 0.0074 16.0 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase RuvB_N PF05496.12 KII95771.1 - 0.0043 16.8 0.1 0.012 15.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KII95771.1 - 0.0044 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KII95771.1 - 0.0045 17.0 0.4 0.014 15.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KII95771.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 KII95771.1 - 0.0077 16.0 0.0 0.028 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KII95771.1 - 0.026 14.1 0.0 0.089 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 KII95771.1 - 0.031 14.7 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KII95771.1 - 0.036 13.9 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KII95771.1 - 0.043 14.2 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KII95771.1 - 0.05 14.1 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KII95771.1 - 0.07 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KII95771.1 - 0.071 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 KII95771.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 KII95771.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KII95771.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 KII95771.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain CLASP_N PF12348.8 KII95772.1 - 1.1e-73 247.6 0.2 4.4e-67 226.0 0.0 3.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 KII95772.1 - 1.2e-07 31.4 4.1 1.2 9.5 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 KII95772.1 - 7.9e-05 22.8 0.3 1.4 9.0 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KII95772.1 - 0.00025 21.5 8.6 0.072 13.6 0.1 4.5 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 KII95772.1 - 0.0004 20.7 7.0 0.71 10.3 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats MMS19_C PF12460.8 KII95772.1 - 2.2 7.3 5.2 0.6 9.2 0.1 2.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Rhomboid PF01694.22 KII95773.1 - 2.1e-24 86.2 5.6 2.1e-24 86.2 5.6 1.5 2 0 0 2 2 2 1 Rhomboid family Sedlin_N PF04628.13 KII95774.1 - 2.8e-36 124.5 0.2 1.2e-35 122.5 0.2 1.8 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KII95774.1 - 3.4e-09 36.8 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Actin PF00022.19 KII95776.1 - 4e-115 384.7 0.0 4.6e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KII95776.1 - 5.9e-07 28.6 0.1 0.021 13.7 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein BOP1NT PF08145.12 KII95777.1 - 1.3e-101 340.0 6.9 1.7e-101 339.5 6.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KII95777.1 - 2.2e-17 63.1 12.5 0.0014 19.4 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95777.1 - 0.00013 22.1 0.0 2.8 8.3 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 KII95777.1 - 9.2 6.3 9.8 18 5.3 9.8 1.6 1 0 0 1 1 1 0 YL1 nuclear protein F-box-like PF12937.7 KII95779.1 - 7e-09 35.4 1.4 2e-08 34.0 1.4 1.9 1 0 0 1 1 1 1 F-box-like Rdx PF10262.9 KII95780.1 - 5.7e-21 74.5 0.0 6.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF2423 PF10338.9 KII95781.1 - 3.4e-14 52.8 6.5 7.6e-14 51.7 6.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) LSM PF01423.22 KII95782.1 - 7.3e-21 73.6 0.0 8e-21 73.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KII95782.1 - 0.0046 17.1 0.0 0.0051 16.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KII95783.1 - 3.4e-19 68.9 0.4 5.7e-19 68.2 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2458 PF10454.9 KII95783.1 - 0.0071 16.0 0.5 0.01 15.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Histone PF00125.24 KII95783.1 - 0.053 13.9 0.2 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PfkB PF00294.24 KII95784.1 - 2.1e-13 50.3 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KII95784.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase ACPS PF01648.20 KII95785.1 - 1.7e-12 47.5 0.0 2.7e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily F-box-like PF12937.7 KII95786.1 - 0.0038 17.1 0.3 0.0081 16.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII95786.1 - 0.1 12.5 1.8 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 F-box domain F-box_4 PF15966.5 KII95786.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box tRNA-synt_2 PF00152.20 KII95787.1 - 4.6e-89 298.6 0.0 1e-88 297.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KII95787.1 - 2.6e-06 27.3 0.0 7.5e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain IMD PF08397.11 KII95788.1 - 3.1e-05 23.5 3.0 4.5e-05 22.9 3.0 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain ARD PF03079.14 KII95788.1 - 0.0011 19.1 1.3 0.0019 18.4 1.3 1.3 1 0 0 1 1 1 1 ARD/ARD' family Phage_int_SAM_2 PF12834.7 KII95788.1 - 0.088 13.5 0.2 0.23 12.1 0.2 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal BAR_3 PF16746.5 KII95788.1 - 0.2 11.3 4.2 0.29 10.8 4.2 1.2 1 0 0 1 1 1 0 BAR domain of APPL family QWRF PF04484.12 KII95788.1 - 7.4 6.2 9.4 0.54 9.9 3.7 1.9 2 0 0 2 2 2 0 QWRF family Ribosomal_L19 PF01245.20 KII95789.1 - 1.2e-12 47.7 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_1 PF00076.22 KII95790.1 - 2.5e-17 62.4 0.0 4.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 KII95791.1 - 6e-34 117.3 0.0 9.6e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII95791.1 - 7.5e-10 38.8 12.3 1.4e-09 37.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KII95791.1 - 0.027 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF682 PF05081.12 KII95791.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF682) Acyl-CoA_dh_1 PF00441.24 KII95792.1 - 1e-26 93.9 0.2 1.6e-26 93.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII95792.1 - 1.7e-18 66.6 0.0 1.4e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KII95792.1 - 3.4e-12 46.8 0.3 3.4e-12 46.8 0.3 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KII95792.1 - 7e-11 42.8 0.0 1.7e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Suc_Fer-like PF06999.12 KII95793.1 - 4.9e-53 179.9 0.0 6.4e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ANAPC1 PF12859.7 KII95794.1 - 4.6 7.8 10.1 6.8 7.3 10.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Suc_Fer-like PF06999.12 KII95795.1 - 8.7e-50 169.3 0.0 1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pkinase PF00069.25 KII95796.1 - 2.1e-66 224.0 0.0 2.7e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KII95796.1 - 2.7e-29 102.3 0.0 3.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KII95796.1 - 1.6e-17 63.9 2.7 2.1e-17 63.5 0.1 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KII95796.1 - 8.9e-09 35.1 0.1 2.7e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KII95796.1 - 1.2e-08 35.2 0.0 2.4e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 KII95796.1 - 2.9e-07 29.8 0.0 5.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KII95796.1 - 0.0032 17.1 0.1 0.54 9.9 0.1 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KII95796.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KII95796.1 - 0.037 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_S1 PF05827.12 KII95798.1 - 1.2 9.0 4.1 3 7.7 0.6 2.8 3 0 0 3 3 3 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Diphthamide_syn PF01866.17 KII95800.1 - 2e-95 319.8 0.0 8.6e-58 196.2 0.0 2.5 2 1 0 2 2 2 2 Putative diphthamide synthesis protein NPC1_N PF16414.5 KII95801.1 - 2.3e-82 276.2 4.9 3.7e-82 275.6 4.9 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KII95801.1 - 3e-65 220.8 12.5 2.3e-36 125.2 0.3 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 KII95801.1 - 5.7e-42 143.2 15.2 3.6e-22 78.9 0.1 3.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KII95801.1 - 1.6e-05 22.9 6.5 1.6e-05 22.9 6.5 1.9 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KII95801.1 - 9e-05 22.4 0.3 0.00017 21.5 0.3 1.3 1 0 0 1 1 1 1 Folate receptor family RRM_1 PF00076.22 KII95802.1 - 1.6e-12 47.1 0.0 1e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII95802.1 - 3.5e-07 29.9 0.0 4.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 KII95803.1 - 1.8e-06 28.1 14.0 6.8e-05 23.1 3.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KII95803.1 - 5.6e-05 23.4 2.3 5.6e-05 23.4 2.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KII95803.1 - 0.0016 19.1 18.9 0.094 13.6 1.0 3.4 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 KII95803.1 - 0.18 12.3 9.9 15 6.1 9.9 2.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KII95803.1 - 0.51 10.7 9.3 8.6 6.8 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NAD_binding_1 PF00175.21 KII95804.1 - 5.2e-10 39.9 0.0 7.1e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KII95804.1 - 2.9e-08 34.0 0.0 7.1e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KII95804.1 - 9.6e-06 25.8 0.0 0.0084 16.2 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Amidohydro_2 PF04909.14 KII95805.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Kinesin PF00225.23 KII95806.1 - 7.3e-107 357.1 0.0 1.2e-106 356.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KII95806.1 - 5.1e-26 91.4 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Apolipoprotein PF01442.18 KII95806.1 - 3.3 7.5 13.6 0.15 11.9 2.4 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FAM76 PF16046.5 KII95806.1 - 6.6 6.0 9.2 0.23 10.8 1.1 2.4 3 0 0 3 3 3 0 FAM76 protein EMP24_GP25L PF01105.24 KII95807.1 - 3e-49 167.4 0.5 3.4e-49 167.2 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ran_BP1 PF00638.18 KII95808.1 - 1.8e-49 167.0 0.2 1.8e-49 167.0 0.2 1.6 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 KII95808.1 - 0.00012 22.0 0.3 0.00077 19.4 0.3 2.0 1 1 0 1 1 1 1 WH1 domain CK2S PF15011.6 KII95808.1 - 0.042 13.7 0.2 0.077 12.9 0.2 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate VID27_PH PF17747.1 KII95808.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain AAA_2 PF07724.14 KII95809.1 - 1.8e-34 119.3 0.0 3.2e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KII95809.1 - 1.5e-13 51.3 0.0 5.9e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KII95809.1 - 5.3e-11 42.4 0.0 1.4e-10 41.1 0.0 1.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KII95809.1 - 2.5e-05 24.3 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KII95809.1 - 3.3e-05 24.2 0.5 0.0016 18.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KII95809.1 - 0.00064 20.1 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KII95809.1 - 0.00089 18.7 0.0 0.025 14.0 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KII95809.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KII95809.1 - 0.0023 17.1 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KII95809.1 - 0.0092 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 KII95809.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 KII95809.1 - 0.019 14.1 0.0 0.048 12.7 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 KII95809.1 - 0.02 15.4 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KII95809.1 - 0.022 14.5 0.1 0.38 10.5 0.0 2.4 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KII95809.1 - 0.025 14.6 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 KII95809.1 - 0.035 13.9 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KII95809.1 - 0.053 13.2 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KII95809.1 - 0.063 13.6 0.2 0.41 11.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KII95809.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 KII95809.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein DEAD PF00270.29 KII95809.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KII95809.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KII95809.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KII95809.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HeH PF12949.7 KII95809.1 - 0.18 11.5 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 HeH/LEM domain SRPRB PF09439.10 KII95809.1 - 0.23 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Cactin_mid PF10312.9 KII95810.1 - 2.9e-64 216.4 6.5 2.9e-64 216.4 6.5 3.2 4 1 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KII95810.1 - 3.3e-60 201.5 6.9 7.3e-60 200.4 6.9 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cyclin PF08613.11 KII95811.1 - 0.041 14.2 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Cyclin ThiF PF00899.21 KII95812.1 - 2.1e-105 351.5 0.0 1e-67 228.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KII95812.1 - 5.7e-90 301.6 0.0 9.3e-90 300.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KII95812.1 - 1.3e-35 121.4 0.5 2.8e-35 120.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KII95812.1 - 2.7e-32 111.3 0.6 5.8e-32 110.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KII95812.1 - 1.2e-26 92.7 0.4 3.3e-26 91.3 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Cyclin PF08613.11 KII95813.1 - 0.0058 17.0 0.0 0.0097 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.8 KII95814.1 - 1.4e-121 406.8 0.1 3.1e-64 217.8 2.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 KII95814.1 - 6.7e-77 258.5 0.0 1.1e-76 257.9 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Forkhead PF00250.18 KII95815.1 - 1e-30 105.8 0.0 1.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain CIAPIN1 PF05093.13 KII95816.1 - 1.6e-31 108.8 4.0 2.5e-31 108.2 4.0 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KII95816.1 - 0.0001 22.5 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-HIT PF04438.16 KII95817.1 - 3.2e-09 36.5 10.7 4.8e-09 35.9 10.7 1.3 1 0 0 1 1 1 1 HIT zinc finger FoP_duplication PF13865.6 KII95817.1 - 0.19 12.3 6.5 0.44 11.1 6.5 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Med18 PF09637.10 KII95818.1 - 3e-06 27.3 0.0 0.00057 19.8 0.0 2.0 1 1 1 2 2 2 2 Med18 protein ADH_N PF08240.12 KII95819.1 - 2.2e-29 101.5 2.9 2.2e-29 101.5 2.9 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII95819.1 - 1e-18 67.6 0.3 2e-18 66.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KII95819.1 - 1.9e-08 34.0 0.5 0.00064 19.3 0.1 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KII95819.1 - 9.5e-05 23.5 0.1 0.00016 22.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KII95819.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KII95819.1 - 0.038 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_4 PF12799.7 KII95820.1 - 0.012 16.0 5.9 1.8 9.1 0.2 5.5 4 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KII95820.1 - 0.095 12.5 2.1 19 5.1 0.1 4.4 5 0 0 5 5 5 0 Leucine rich repeat zf-RING_5 PF14634.6 KII95823.1 - 5.2e-08 32.7 7.1 9.1e-08 31.9 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KII95823.1 - 4.8e-05 23.6 4.2 9.1e-05 22.7 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KII95823.1 - 5.5e-05 22.9 3.7 0.00011 22.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KII95823.1 - 5.7e-05 22.9 6.1 0.00011 22.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII95823.1 - 0.00013 21.7 6.7 0.00024 20.9 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KII95823.1 - 0.00018 21.3 5.4 0.00036 20.3 5.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KII95823.1 - 0.0027 17.5 3.3 0.0047 16.8 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_1 PF14446.6 KII95823.1 - 0.0076 16.2 0.3 0.0076 16.2 0.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KII95823.1 - 0.011 15.5 2.7 0.022 14.5 2.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KII95823.1 - 0.016 15.2 1.8 0.016 15.2 1.8 1.8 2 0 0 2 2 2 0 Double zinc ribbon zf-rbx1 PF12678.7 KII95823.1 - 0.017 15.4 3.3 0.039 14.2 3.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KII95823.1 - 0.035 14.1 4.2 0.061 13.4 1.4 2.5 1 1 1 2 2 2 0 RING-type zinc-finger DUF5082 PF16888.5 KII95823.1 - 0.037 14.3 0.6 0.037 14.3 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) zf-P11 PF03854.14 KII95823.1 - 0.039 13.6 3.2 0.081 12.6 3.2 1.5 1 0 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.11 KII95823.1 - 0.082 13.0 5.9 0.17 12.0 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C4H2 PF10146.9 KII95823.1 - 0.18 12.1 7.7 0.036 14.4 1.9 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein UPF0242 PF06785.11 KII95823.1 - 0.24 11.5 4.7 0.43 10.7 4.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_4 PF15227.6 KII95823.1 - 1 9.6 5.6 2.4 8.4 4.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 KII95823.1 - 1.5 8.9 5.7 3 7.9 5.7 1.5 1 0 0 1 1 1 0 zinc-ribbons DUF4407 PF14362.6 KII95823.1 - 1.6 8.0 8.3 2.1 7.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IBR PF01485.21 KII95823.1 - 4.2 7.7 6.4 1 9.7 1.9 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF2236 PF09995.9 KII95824.1 - 2.2e-10 41.1 0.3 5e-10 40.0 0.3 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GAS2 PF02187.17 KII95825.1 - 5.8e-13 48.7 0.1 2e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF2730 PF10805.8 KII95825.1 - 0.0042 17.1 1.7 0.057 13.5 0.2 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) DIL PF01843.19 KII95825.1 - 0.012 15.9 0.1 0.068 13.5 0.1 2.3 1 0 0 1 1 1 0 DIL domain NPV_P10 PF05531.12 KII95825.1 - 2 9.0 6.5 35 4.9 0.1 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Helicase_C PF00271.31 KII95827.1 - 1.1e-11 45.1 0.0 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KII95827.1 - 1.6e-06 28.0 0.1 5.9e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase MeaB PF03308.16 KII95827.1 - 0.024 13.6 1.3 0.047 12.7 1.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CAF-1_p150 PF11600.8 KII95827.1 - 0.081 12.6 45.2 0.14 11.9 45.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.11 KII95827.1 - 3.2 7.7 22.0 4.7 7.2 22.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.12 KII95827.1 - 3.4 7.4 20.4 6 6.6 20.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 KII95827.1 - 6.2 7.0 13.1 9.6 6.4 13.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family XRN_M PF17846.1 KII95827.1 - 8.1 5.3 11.2 15 4.4 11.2 1.5 1 0 0 1 1 1 0 Xrn1 helical domain Borrelia_P83 PF05262.11 KII95827.1 - 8.9 4.7 31.6 13 4.1 31.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CHAD PF05235.14 KII95828.1 - 0.21 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 CHAD domain DUF2514 PF10721.9 KII95829.1 - 0.023 14.7 1.3 0.026 14.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Transp_cyt_pur PF02133.15 KII95834.1 - 3e-74 250.4 34.9 3.5e-74 250.2 34.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Iso_dh PF00180.20 KII95835.1 - 9.9e-99 330.8 0.0 1.1e-98 330.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.28 KII95838.1 - 0.0024 18.3 0.1 0.0033 17.8 0.0 1.3 1 1 0 1 1 1 1 SET domain DUF2373 PF10180.9 KII95839.1 - 1.6e-19 69.5 0.1 2.4e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Arf PF00025.21 KII95840.1 - 1.5e-70 236.2 0.0 1.7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KII95840.1 - 2.6e-14 53.0 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KII95840.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KII95840.1 - 1.8e-13 50.4 0.1 1.4e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KII95840.1 - 2.1e-09 37.2 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KII95840.1 - 4.2e-09 36.1 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KII95840.1 - 0.00083 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 KII95841.1 - 2.8e-18 65.9 10.5 0.00014 22.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95841.1 - 0.00011 22.4 0.0 0.057 13.7 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.6 KII95841.1 - 1 9.7 3.5 0.89 10.0 1.5 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IQCJ-SCHIP1 PF15157.6 KII95843.1 - 0.0044 16.9 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif Plavaka PF18759.1 KII95844.1 - 7.1e-127 423.1 0.0 8.9e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase WD40 PF00400.32 KII95850.1 - 8.2e-20 70.8 7.8 7.8e-05 23.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95850.1 - 1.9e-05 24.9 0.0 0.015 15.6 0.0 3.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Helicase_C PF00271.31 KII95852.1 - 1.5e-11 44.6 0.0 5.6e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Tet_JBP PF12851.7 KII95853.1 - 9.4e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily KDZ PF18758.1 KII95855.1 - 8.9e-40 136.7 0.0 1.9e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KII95855.1 - 2.8e-27 95.0 0.1 1.8e-24 85.9 0.0 2.5 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 KII95855.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF2407_C PF13373.6 KII95856.1 - 2.5 8.3 7.3 1.8 8.7 4.0 2.4 1 1 1 2 2 2 0 DUF2407 C-terminal domain DUF4407 PF14362.6 KII95856.1 - 9.7 5.4 12.4 1 8.6 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 KII95857.1 - 0.04 12.6 3.8 0.062 12.0 3.8 1.2 1 0 0 1 1 1 0 AAA domain TLP-20 PF06088.11 KII95857.1 - 0.057 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Zn_clus PF00172.18 KII95857.1 - 1.5 9.0 12.1 0.34 11.1 3.3 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.12 KII95858.1 - 8.4 5.7 7.1 12 5.2 7.1 1.1 1 0 0 1 1 1 0 SDA1 DEAD PF00270.29 KII95860.1 - 6.8e-09 35.7 0.0 9.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase MerR-DNA-bind PF09278.11 KII95862.1 - 0.1 13.1 1.9 0.12 13.0 0.5 1.9 2 0 0 2 2 2 0 MerR, DNA binding PGA2 PF07543.12 KII95862.1 - 0.18 11.7 6.4 0.031 14.3 2.6 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 SET PF00856.28 KII95864.1 - 1.3e-12 48.4 0.3 1.7e-11 44.8 0.3 2.3 1 1 0 1 1 1 1 SET domain OFeT_1 PF16955.5 KII95865.1 - 0.4 10.3 8.4 0.076 12.7 3.9 1.9 1 1 1 2 2 2 0 Ferrous iron uptake permease, iron-lead transporter Aminotran_1_2 PF00155.21 KII95866.1 - 1.3e-75 254.8 0.0 1.7e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KII95866.1 - 7.2e-05 21.5 0.0 0.00013 20.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KII95866.1 - 0.00044 19.3 0.0 0.00092 18.3 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KII95866.1 - 0.03 14.1 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Preseq_ALAS PF09029.10 KII95866.1 - 8.7 6.9 11.6 1.3e+03 -0.1 11.6 2.8 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Aminotran_3 PF00202.21 KII95867.1 - 4.3e-97 325.3 0.0 6.8e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_1 PF00561.20 KII95868.1 - 9.9e-23 81.1 0.0 4.7e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KII95868.1 - 2.6e-16 59.6 0.0 2.7e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII95868.1 - 2.1e-14 54.7 0.2 5.8e-14 53.2 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KII95868.1 - 6.3e-06 26.0 0.0 2.6e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KII95868.1 - 0.00018 21.5 0.0 0.056 13.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KII95868.1 - 0.00049 19.8 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KII95868.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 KII95868.1 - 0.0044 15.8 0.0 0.01 14.5 0.0 1.5 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.11 KII95868.1 - 0.013 15.5 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 KII95868.1 - 0.14 11.6 0.2 0.4 10.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) cwf21 PF08312.12 KII95869.1 - 7e-15 54.9 12.4 7e-15 54.9 12.4 2.4 3 0 0 3 3 3 1 cwf21 domain Pro-rich PF15240.6 KII95869.1 - 1.6 9.0 41.6 3.6 7.8 41.6 1.6 1 0 0 1 1 1 0 Proline-rich Presenilin PF01080.17 KII95869.1 - 5.3 5.7 4.5 6.9 5.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KII95869.1 - 6.5 4.9 12.9 8.7 4.5 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein MT-A70 PF05063.14 KII95870.1 - 1.2e-57 194.6 0.0 1.8e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 MT-A70 adh_short PF00106.25 KII95871.1 - 1.3e-10 41.0 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KII95871.1 - 1.5e-07 31.3 0.0 1.9e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Asp PF00026.23 KII95873.1 - 5.8e-74 249.3 3.1 6.9e-74 249.1 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII95873.1 - 2.8e-07 30.9 4.8 0.00032 21.0 0.2 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII95873.1 - 0.0055 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Borrelia_P13 PF05628.12 KII95873.1 - 0.084 12.8 0.8 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Borrelia membrane protein P13 DUF1918 PF08940.11 KII95873.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Asp PF00026.23 KII95874.1 - 9.3e-71 238.8 1.8 1.2e-70 238.5 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KII95874.1 - 4.5e-09 36.8 3.0 0.0036 17.6 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KII95874.1 - 0.0063 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KII95874.1 - 0.023 15.4 0.4 15 6.3 0.1 3.0 2 1 0 2 2 2 0 Aspartyl protease TMEM208_SND2 PF05620.11 KII95875.1 - 3.4e-55 186.4 0.0 3.8e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Myb_DNA-binding PF00249.31 KII95876.1 - 5.2e-40 135.4 11.0 1.9e-12 47.1 0.3 5.6 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KII95876.1 - 2.6e-34 117.3 0.1 2.2e-10 40.6 0.0 5.4 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KII95876.1 - 2.6e-06 27.2 0.4 0.027 14.4 0.2 3.0 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KII95876.1 - 0.0041 17.1 0.0 7.1 6.7 0.0 3.3 2 1 0 2 2 2 2 SLIDE DUF3606 PF12244.8 KII95876.1 - 0.0052 16.7 0.5 4.7 7.2 0.1 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3606) Myb_DNA-bind_4 PF13837.6 KII95876.1 - 0.088 13.2 14.2 3.7 8.0 0.2 6.2 5 3 0 5 5 5 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 KII95876.1 - 0.16 12.2 6.0 1.8 8.8 0.1 3.7 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 Atg29_N PF18388.1 KII95876.1 - 3.7 7.4 8.2 9.9 6.1 0.4 3.6 4 0 0 4 4 4 0 Atg29 N-terminal domain TAF8_C PF10406.9 KII95877.1 - 1.2e-09 38.5 1.4 4.1e-09 36.8 1.4 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KII95877.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CYYR1 PF10873.8 KII95877.1 - 0.0057 17.1 3.9 0.0057 17.1 3.9 2.3 2 1 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Flavokinase PF01687.17 KII95878.1 - 9.7e-33 112.8 0.0 1.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.19 KII95879.1 - 4.2e-10 40.0 0.2 6.2e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 RNA_pol_L PF01193.24 KII95879.1 - 0.1 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain UCR_UQCRX_QCR9 PF05365.12 KII95880.1 - 4e-26 90.7 3.2 4.5e-26 90.5 3.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.6 KII95880.1 - 0.016 15.3 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain Longin PF13774.6 KII95881.1 - 2.5e-25 88.3 0.0 3.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KII95881.1 - 1.2e-14 53.8 0.1 2.1e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Nab1 PF04902.12 KII95881.1 - 0.092 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Conserved region in Nab1 DUF4646 PF15496.6 KII95882.1 - 1.2e-07 32.4 0.4 0.0029 18.2 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) SR-25 PF10500.9 KII95882.1 - 0.0051 16.4 8.5 0.0051 16.4 8.5 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Caldesmon PF02029.15 KII95882.1 - 0.89 8.3 30.1 0.98 8.1 14.2 2.1 2 0 0 2 2 2 0 Caldesmon Rrn6 PF10214.9 KII95882.1 - 1.3 7.4 17.2 0.074 11.6 2.3 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 KII95882.1 - 3.3 5.9 29.2 0.033 12.5 10.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Nop53 PF07767.11 KII95882.1 - 3.4 7.0 28.3 0.063 12.7 5.8 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) IF-2B PF01008.17 KII95883.1 - 3.1e-84 282.5 0.0 3.5e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_trans_4_4 PF13579.6 KII95883.1 - 0.065 13.7 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF962 PF06127.11 KII95884.1 - 9.7e-23 80.1 3.6 4.2e-22 78.0 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Osw5 PF17062.5 KII95884.1 - 0.18 11.9 9.0 0.97 9.6 0.2 2.3 2 0 0 2 2 2 0 Outer spore wall 5 IPK PF03770.16 KII95885.1 - 3.4e-51 173.9 0.0 7.7e-51 172.8 0.0 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase Forkhead PF00250.18 KII95886.1 - 2.3e-25 88.7 0.0 4.9e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 KII95886.1 - 7e-08 32.7 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 FHA domain MTP18 PF10558.9 KII95887.1 - 6.7e-62 208.4 3.7 9.2e-61 204.7 3.7 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) adh_short_C2 PF13561.6 KII95888.1 - 9.3e-64 215.2 0.3 1.2e-63 214.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII95888.1 - 8.9e-47 159.1 0.2 1.1e-46 158.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII95888.1 - 1.4e-06 28.4 0.1 2.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KII95888.1 - 0.0034 17.3 1.2 0.0044 16.9 0.2 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KII95888.1 - 0.1 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain dUTPase PF00692.19 KII95890.1 - 4.5e-41 139.5 0.0 5.5e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 dUTPase Glu-tRNAGln PF02686.15 KII95891.1 - 0.032 14.5 0.0 0.078 13.3 0.0 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit MRP-S34 PF16053.5 KII95892.1 - 7.3e-12 45.1 0.8 1.1e-11 44.5 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Peptidase_M43 PF05572.13 KII95893.1 - 1.6e-17 63.8 0.1 2.9e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KII95893.1 - 1.4e-06 28.6 0.8 2.7e-06 27.7 0.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KII95893.1 - 0.00026 21.5 0.0 0.00041 20.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KII95893.1 - 0.0033 17.3 0.4 0.0045 16.9 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KII95893.1 - 0.014 15.0 4.3 0.037 13.7 3.8 1.9 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KII95893.1 - 0.015 14.3 0.4 0.02 13.9 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.8 KII95893.1 - 0.077 12.6 0.6 0.12 11.9 0.6 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase ACBP PF00887.19 KII95894.1 - 2.2e-17 63.0 0.0 3.7e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein ADH_N PF08240.12 KII95895.1 - 4.7e-21 74.7 2.1 1.1e-20 73.6 2.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KII95895.1 - 6.1e-20 71.5 0.7 1.2e-19 70.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KII95895.1 - 0.0024 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KII95895.1 - 0.06 12.6 0.4 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLLAC PF15675.5 KII95895.1 - 0.49 10.0 2.5 1 9.0 2.5 1.5 1 0 0 1 1 1 0 CLLAC-motif containing domain Vfa1 PF08432.10 KII95896.1 - 1.9e-37 129.4 0.0 2.2e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 MAP65_ASE1 PF03999.12 KII95896.1 - 0.19 10.4 5.8 0.24 10.0 5.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Rtf2 PF04641.12 KII95896.1 - 0.91 8.8 6.7 1.2 8.4 6.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF899 PF05988.12 KII95896.1 - 1.1 8.8 3.2 2.1 7.8 3.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) ANAPC_CDC26 PF10471.9 KII95896.1 - 5.5 7.9 9.7 0.28 12.0 2.1 2.1 1 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Nucleoside_tran PF01733.18 KII95897.1 - 2.7e-38 132.1 8.9 2.7e-38 132.1 8.9 1.6 2 0 0 2 2 2 1 Nucleoside transporter Ank_2 PF12796.7 KII95899.1 - 9.9e-17 61.3 0.6 1.1e-08 35.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KII95899.1 - 1.6e-15 56.7 1.2 1.5e-06 28.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KII95899.1 - 3.8e-15 56.0 1.4 8.3e-10 39.0 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII95899.1 - 4.7e-12 45.0 0.8 0.00024 21.3 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KII95899.1 - 5.2e-12 45.8 0.8 3e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KII95899.1 - 0.00014 21.7 0.1 0.0014 18.4 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain KxDL PF10241.9 KII95899.1 - 0.014 15.7 0.2 0.042 14.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Cortex-I_coil PF09304.10 KII95899.1 - 0.32 11.2 2.9 0.8 9.9 2.9 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil CREPT PF16566.5 KII95899.1 - 1.2 9.2 4.6 2 8.5 1.0 2.5 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DSPn PF14671.6 KII95900.1 - 4.6e-41 140.6 0.0 2.2e-39 135.1 0.0 2.5 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KII95900.1 - 1.1e-15 57.6 0.0 2.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KII95900.1 - 0.00044 19.9 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KII95900.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KII95900.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.17 KII95901.1 - 1.2e-128 429.1 0.0 1.4e-128 428.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Amidase PF01425.21 KII95903.1 - 2.6e-102 343.1 0.0 3.3e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.18 KII95904.1 - 1.1e-06 28.7 11.1 2.2e-06 27.7 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 KII95904.1 - 0.0011 17.6 0.0 0.0039 15.7 0.0 1.7 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B Adeno_GP19K PF04881.13 KII95904.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus GP19K PhyH PF05721.13 KII95905.1 - 2.8e-11 44.1 0.0 4.4e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KII95905.1 - 0.069 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 KII95905.1 - 0.12 11.1 0.0 16 4.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 KII95906.1 - 1.6e-85 287.6 17.8 2e-85 287.3 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KII95906.1 - 9.2e-30 103.7 30.0 7.8e-25 87.5 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KII95906.1 - 7e-05 21.4 1.4 0.00015 20.4 1.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.13 KII95906.1 - 0.7 10.5 3.2 0.31 11.7 0.3 2.0 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_3 PF00003.22 KII95907.1 - 0.0003 20.6 7.3 0.00046 20.0 7.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CopD PF05425.13 KII95907.1 - 0.0089 16.4 2.2 0.0089 16.4 2.2 2.3 2 1 0 2 2 2 1 Copper resistance protein D STE3 PF02076.15 KII95907.1 - 0.016 14.4 5.4 0.0089 15.3 3.1 1.8 1 1 1 2 2 2 0 Pheromone A receptor DUF2070 PF09843.9 KII95907.1 - 0.69 8.1 6.8 1.8 6.8 6.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L12 PF00542.19 KII95908.1 - 4.1e-22 78.3 5.2 4.3e-20 71.8 2.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KII95908.1 - 3.6e-13 49.0 3.6 1.7e-12 46.8 1.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain VirionAssem_T7 PF11653.8 KII95908.1 - 0.069 13.7 0.5 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein Ribosomal_60s PF00428.19 KII95908.1 - 0.71 10.5 7.6 0.21 12.2 0.7 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Not3 PF04065.15 KII95909.1 - 1.7e-89 299.3 22.0 2.5e-89 298.7 22.0 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KII95909.1 - 1.7e-43 147.9 9.5 1.7e-43 147.9 9.5 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KII95909.1 - 0.00071 19.9 2.1 0.00071 19.9 2.1 2.5 3 0 0 3 3 3 1 Syntaxin-like protein Cep57_MT_bd PF06657.13 KII95909.1 - 2.7 8.5 8.6 0.26 11.7 0.9 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SH3_1 PF00018.28 KII95911.1 - 1.8e-22 78.7 0.0 2.4e-10 39.8 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KII95911.1 - 1.3e-17 63.3 0.4 4.2e-09 36.1 0.0 3.5 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KII95911.1 - 7.1e-16 57.6 0.1 1.3e-08 34.3 0.0 3.8 4 0 0 4 4 4 2 Variant SH3 domain PX PF00787.24 KII95911.1 - 2.4e-07 30.7 0.0 4.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 KII95911.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 PB1 domain NDUFA12 PF05071.16 KII95912.1 - 6e-33 113.6 4.4 6e-33 113.6 4.4 1.3 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.24 KII95913.1 - 2.7e-49 168.7 0.0 3.3e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ribosomal_S7e PF01251.18 KII95914.1 - 2.8e-85 284.7 3.8 4.5e-85 284.0 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 KII95914.1 - 4.1e-15 54.9 3.1 5.5e-05 22.8 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII95914.1 - 1.9e-10 40.0 2.5 0.0023 17.9 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KII95914.1 - 4.7e-05 23.8 0.7 0.00071 20.0 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII95914.1 - 9e-05 22.4 0.7 0.017 15.3 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KII95914.1 - 0.0061 17.3 0.1 1.7 9.6 0.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KII95914.1 - 0.0072 16.6 2.6 0.38 11.1 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KII95914.1 - 0.018 15.3 1.6 0.035 14.3 1.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KII95914.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 KII95915.1 - 7.9e-47 158.9 0.0 8.9e-43 145.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KII95915.1 - 4.1e-32 110.9 0.0 6.2e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KII95915.1 - 5.4e-11 42.3 0.0 9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KII95915.1 - 1.3e-06 28.5 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KII95915.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KII95915.1 - 0.01 15.3 0.1 0.023 14.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KII95915.1 - 0.012 15.3 0.1 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KII95915.1 - 0.027 14.7 0.1 0.066 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KII95915.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KII95915.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KII95915.1 - 0.08 13.0 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KII95915.1 - 0.089 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KII95915.1 - 0.14 11.7 0.3 0.24 10.9 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AMMECR1 PF01871.17 KII95916.1 - 1.9e-43 147.9 0.0 6.9e-43 146.1 0.0 1.7 1 1 0 1 1 1 1 AMMECR1 PPR_3 PF13812.6 KII95917.1 - 1.7e-09 37.6 0.3 0.037 14.1 0.0 3.6 2 1 2 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KII95917.1 - 4.7e-09 35.8 1.8 3.6e-05 23.4 0.0 3.4 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 KII95917.1 - 4.7e-07 29.9 0.6 0.25 11.6 0.0 4.8 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 KII95917.1 - 0.00016 21.7 1.2 0.23 11.8 0.0 4.5 5 0 0 5 5 5 1 PPR repeat Ribosomal_L3 PF00297.22 KII95918.1 - 2.1e-184 612.7 7.6 2.4e-184 612.5 7.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 MRC1 PF09444.10 KII95919.1 - 3.6e-25 89.2 30.0 3.6e-25 89.2 30.0 7.7 5 3 2 7 7 7 1 MRC1-like domain Acyltransferase PF01553.21 KII95921.1 - 7.1e-18 64.5 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.24 KII95922.1 - 1.1e-10 41.6 26.4 5.4e-07 29.7 10.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro_88 PF07470.13 KII95923.1 - 1.5e-24 86.7 0.7 2.1e-24 86.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 THOC2_N PF16134.5 KII95924.1 - 2e-141 472.7 0.0 3.3e-141 472.0 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KII95924.1 - 7e-89 298.0 0.0 1.3e-88 297.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KII95924.1 - 2.2e-30 104.5 0.0 4.3e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.22 KII95925.1 - 8.3e-76 253.4 0.6 1.3e-75 252.8 0.6 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KII95925.1 - 0.00031 20.8 0.0 0.00074 19.6 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KII95925.1 - 0.057 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 KII95926.1 - 5.1e-26 91.8 0.0 9.7e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KII95926.1 - 4.7e-09 36.5 0.1 0.00018 21.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KII95926.1 - 8.4e-07 28.6 0.1 1.5e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KII95926.1 - 3.2e-05 23.8 0.0 0.067 12.9 0.0 2.1 1 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KII95926.1 - 6.1e-05 23.2 0.0 0.00025 21.2 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 KII95926.1 - 0.00033 19.5 0.0 0.086 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KII95926.1 - 0.0041 16.8 0.0 0.0096 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ribosomal_S9 PF00380.19 KII95926.1 - 0.0058 17.1 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 AAA_23 PF13476.6 KII95926.1 - 0.0068 16.9 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KII95926.1 - 0.0089 15.8 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KII95926.1 - 0.017 15.5 0.0 0.055 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KII95926.1 - 0.025 14.9 0.0 0.49 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KII95926.1 - 0.048 12.9 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 KII95926.1 - 0.056 12.6 0.1 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KII95926.1 - 0.07 13.6 0.0 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KII95926.1 - 0.14 12.1 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 KII95926.1 - 0.15 12.2 0.0 0.57 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KII95926.1 - 0.19 12.3 0.3 1.4 9.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KII95926.1 - 0.2 11.7 0.1 0.38 10.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain GDPD PF03009.17 KII95927.1 - 1.3e-09 38.2 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KII95928.1 - 9.3e-26 90.2 0.1 8.3e-18 64.8 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII95928.1 - 5.7e-19 68.2 0.3 1.8e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII95928.1 - 2.9e-18 65.7 2.2 9.3e-07 29.0 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KII95928.1 - 1.2e-17 63.5 4.1 0.00012 22.4 0.0 4.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KII95928.1 - 1.4e-13 49.7 2.5 0.0017 18.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Imm_superinfect PF14373.6 KII95928.1 - 0.081 12.9 0.0 43 4.1 0.0 3.1 3 0 0 3 3 3 0 Superinfection immunity protein SPX PF03105.19 KII95929.1 - 1.4e-28 100.9 6.5 2.1e-10 41.1 0.0 3.1 1 1 1 3 3 3 3 SPX domain CCDC154 PF15450.6 KII95929.1 - 0.23 10.0 1.1 0.31 9.6 1.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Pex2_Pex12 PF04757.14 KII95930.1 - 3e-48 164.4 1.2 3.7e-48 164.1 1.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 KII95930.1 - 1.4e-05 24.8 0.8 1.4e-05 24.8 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KII95930.1 - 6.6e-05 22.7 1.2 0.00012 21.8 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII95930.1 - 0.00032 21.0 0.5 0.00032 21.0 0.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KII95930.1 - 0.013 15.3 0.9 0.013 15.3 0.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII95930.1 - 0.036 14.1 2.9 0.036 14.1 2.9 1.8 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KII95930.1 - 0.058 13.3 1.0 2 8.3 0.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KII95930.1 - 0.29 11.3 6.1 0.11 12.6 2.9 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rubredoxin_2 PF18073.1 KII95930.1 - 1.2 8.9 6.7 4.1 7.2 0.9 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Haem_degrading PF03928.14 KII95931.1 - 5.5e-11 42.6 0.1 1.4e-10 41.3 0.1 1.7 1 1 0 1 1 1 1 Haem-degrading SSB PF00436.25 KII95932.1 - 6.9e-17 61.4 0.0 8.7e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ago_N_1 PF18351.1 KII95932.1 - 0.043 14.2 0.1 0.31 11.5 0.0 2.1 1 1 1 2 2 2 0 Fungal Argonaute N-terminal domain HBS1_N PF08938.10 KII95933.1 - 2.4e-13 50.2 0.5 4.6e-13 49.3 0.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.27 KII95934.1 - 9e-34 116.7 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KII95934.1 - 1.3e-13 51.2 0.1 1.2e-12 48.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KII95934.1 - 2.9e-07 30.8 0.0 6.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII95934.1 - 0.00031 20.8 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KII95934.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 KII95934.1 - 0.15 11.9 0.5 0.66 9.9 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AMPK1_CBM PF16561.5 KII95936.1 - 1.6e-21 76.3 0.2 1.8e-21 76.2 0.2 1.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Methyltransf_16 PF10294.9 KII95938.1 - 2.1e-43 148.1 0.0 2.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KII95938.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KII95938.1 - 0.004 16.6 0.1 0.0051 16.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) BolA PF01722.18 KII95939.1 - 1.3e-12 47.8 0.2 4.7e-12 46.0 0.0 1.9 2 1 0 2 2 2 1 BolA-like protein Mt_ATP-synt_D PF05873.12 KII95940.1 - 9.1e-15 54.8 0.7 1.1e-14 54.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) PCRF PF03462.18 KII95940.1 - 0.12 12.3 1.8 0.16 11.8 1.8 1.2 1 0 0 1 1 1 0 PCRF domain SIMPL PF04402.14 KII95940.1 - 0.15 12.5 2.7 0.17 12.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF2838 PF10998.8 KII95941.1 - 1e-41 141.6 8.2 1e-41 141.6 8.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1640 PF07798.11 KII95941.1 - 0.11 12.5 0.3 0.8 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF5315 PF17242.2 KII95941.1 - 0.12 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) FAD_binding_4 PF01565.23 KII95942.1 - 3.7e-30 104.5 4.2 8.4e-30 103.3 4.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KII95942.1 - 8.3e-07 29.0 0.3 1.9e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like PSCyt1 PF07635.11 KII95942.1 - 0.043 14.4 0.2 0.37 11.4 0.0 2.6 3 1 1 4 4 4 0 Planctomycete cytochrome C A_deamin PF02137.18 KII95943.1 - 3.1e-65 220.8 0.0 3.7e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Con-6 PF10346.9 KII95945.1 - 1.6e-12 47.2 0.8 2.3e-12 46.7 0.8 1.2 1 0 0 1 1 1 1 Conidiation protein 6 MS_channel PF00924.18 KII95947.1 - 7.5e-20 71.4 0.2 1.4e-19 70.4 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KII95947.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EI24 PF07264.11 KII95947.1 - 0.0023 18.2 9.8 0.0046 17.2 4.5 2.2 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) EF-hand_6 PF13405.6 KII95947.1 - 0.0025 17.6 0.1 0.0069 16.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KII95947.1 - 0.0031 16.9 0.0 0.0082 15.6 0.0 1.6 1 0 0 1 1 1 1 EF hand MnhB PF04039.13 KII95947.1 - 0.014 15.7 2.0 0.36 11.1 0.0 2.7 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter ATG16 PF08614.11 KII95948.1 - 0.0089 16.3 24.7 0.017 15.3 24.7 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Importin_rep_2 PF18786.1 KII95948.1 - 0.061 13.2 2.2 14 5.6 0.1 3.0 3 0 0 3 3 3 0 Importin 13 repeat Tyrosinase PF00264.20 KII95948.1 - 0.57 10.4 7.0 0.079 13.2 2.9 1.6 2 0 0 2 2 2 0 Common central domain of tyrosinase GAGA_bind PF06217.12 KII95948.1 - 1.2 9.3 9.9 1.5 9.1 9.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Proteasome PF00227.26 KII95950.1 - 9.2e-54 181.8 0.0 1.2e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII95950.1 - 1.1e-12 47.3 1.7 1.7e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COX15-CtaA PF02628.15 KII95951.1 - 1.2e-106 356.5 9.4 1.4e-106 356.3 9.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2737 PF10930.8 KII95952.1 - 0.39 10.3 0.1 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) RhaA PF06134.11 KII95953.1 - 0.095 11.8 0.2 3.2 6.8 0.0 2.0 1 1 1 2 2 2 0 L-rhamnose isomerase (RhaA) RYDR_ITPR PF01365.21 KII95953.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 RIH domain GPR15L PF15854.5 KII95954.1 - 0.002 18.3 0.9 0.0029 17.8 0.6 1.4 1 1 0 1 1 1 1 G-protein coupled receptor ligand 15 PKD_channel PF08016.12 KII95956.1 - 0.0012 17.6 0.5 0.0012 17.6 0.5 2.4 2 0 0 2 2 2 1 Polycystin cation channel SHP PF03579.13 KII95956.1 - 0.014 15.3 0.4 0.038 14.0 0.4 1.7 1 0 0 1 1 1 0 Small hydrophobic protein Ion_trans PF00520.31 KII95956.1 - 0.62 9.2 18.5 2.7 7.2 18.5 1.9 1 1 0 1 1 1 0 Ion transport protein DUF3445 PF11927.8 KII95957.1 - 1.4e-70 237.4 0.0 1.7e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.16 KII95957.1 - 0.063 12.2 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily adh_short_C2 PF13561.6 KII95958.1 - 4.2e-36 124.7 0.2 4.9e-36 124.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII95958.1 - 3e-28 98.6 0.0 4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII95958.1 - 1.5e-11 44.5 0.0 2.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 KR domain TPIP1 PF15338.6 KII95958.1 - 0.0013 18.8 0.2 0.59 10.2 0.0 2.7 3 0 0 3 3 3 2 p53-regulated apoptosis-inducing protein 1 GDP_Man_Dehyd PF16363.5 KII95958.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KII95958.1 - 0.0042 16.6 0.0 0.0067 15.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.21 KII95959.1 - 6.2e-39 133.9 0.0 7.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.11 KII95960.1 - 1.7e-16 59.8 0.1 2.2e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit CENP-F_N PF10481.9 KII95962.1 - 0.0063 16.2 4.8 0.034 13.8 2.0 2.5 2 0 0 2 2 2 1 Cenp-F N-terminal domain DNA_ligase_aden PF01653.18 KII95962.1 - 0.0085 15.2 0.4 0.029 13.5 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent DNA ligase adenylation domain Pox_A_type_inc PF04508.12 KII95962.1 - 0.072 13.0 0.2 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fez1 PF06818.15 KII95962.1 - 0.43 11.0 10.1 0.88 10.0 10.1 1.6 1 0 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 KII95962.1 - 0.55 10.4 2.4 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 KII95962.1 - 1.4 9.6 10.9 3.4 8.3 6.4 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 KII95962.1 - 3.5 7.8 17.1 1.6 8.9 11.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 KII95962.1 - 5.1 6.9 5.6 19 5.1 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator Isochorismatase PF00857.20 KII95963.1 - 1.1e-28 100.5 0.0 1.5e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Hexokinase_2 PF03727.16 KII95964.1 - 1.9e-73 246.8 0.0 9.3e-72 241.3 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KII95964.1 - 5.6e-63 212.4 0.0 8.4e-63 211.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Flu_NS1 PF00600.19 KII95964.1 - 0.092 12.3 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) Sod_Fe_C PF02777.18 KII95965.1 - 3e-14 53.0 0.0 5.5e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.16 KII95966.1 - 5.6e-48 161.8 1.4 6.3e-48 161.6 1.4 1.0 1 0 0 1 1 1 1 DAD family F-box-like PF12937.7 KII95967.1 - 6.3e-09 35.6 2.8 2e-08 34.0 2.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII95967.1 - 0.79 9.7 5.6 0.13 12.2 1.3 2.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KII95968.1 - 3.1e-10 39.8 2.0 7.1e-10 38.6 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KII95968.1 - 0.065 13.1 1.7 0.21 11.5 1.7 1.9 1 1 0 1 1 1 0 F-box domain Adap_comp_sub PF00928.21 KII95969.1 - 7.9e-36 123.8 0.0 9.9e-35 120.2 0.0 2.0 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Aft1_HRA PF11786.8 KII95972.1 - 4.3e-20 71.8 23.5 6.1e-14 52.1 8.0 4.7 4 1 1 5 5 5 2 Aft1 HRA domain bZIP_1 PF00170.21 KII95972.1 - 3.1e-09 36.8 10.2 5.8e-09 35.9 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KII95972.1 - 0.00088 19.3 9.0 0.0017 18.4 9.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.8 KII95972.1 - 0.00096 19.5 9.6 0.00096 19.5 9.6 4.0 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain PPP4R2 PF09184.11 KII95972.1 - 0.24 10.9 5.8 0.5 9.9 5.8 1.4 1 0 0 1 1 1 0 PPP4R2 Dicty_REP PF05086.12 KII95972.1 - 0.32 8.9 4.3 0.44 8.5 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GEMIN8 PF15348.6 KII95972.1 - 4.1 7.6 8.3 8.5 6.6 8.3 1.6 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 bZIP_Maf PF03131.17 KII95972.1 - 8.1 7.0 15.2 0.38 11.3 5.6 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.32 KII95974.1 - 6.8e-75 245.1 50.9 8.8e-10 39.0 0.2 10.1 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII95974.1 - 3.4e-16 59.3 16.5 0.025 14.9 0.4 8.7 1 1 7 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KII95974.1 - 4.6e-09 36.0 0.4 0.045 13.1 0.2 4.6 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KII95974.1 - 3.5e-08 32.8 6.1 0.73 8.7 0.0 7.1 1 1 7 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KII95974.1 - 6.3e-08 33.2 1.9 7.4e-07 29.7 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KII95974.1 - 2.2e-07 30.9 0.0 7.2e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KII95974.1 - 6.7e-05 22.7 2.3 13 5.8 0.0 7.1 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat AAA PF00004.29 KII95974.1 - 0.011 16.2 0.0 0.035 14.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KII95974.1 - 0.017 14.4 0.0 0.05 12.8 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain HARP PF07443.13 KII95974.1 - 0.029 14.0 0.1 9.8 5.9 0.0 3.6 3 0 0 3 3 3 0 HepA-related protein (HARP) ATPase_2 PF01637.18 KII95974.1 - 0.048 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PQQ PF01011.21 KII95974.1 - 0.066 13.2 0.6 1.1e+02 2.9 0.0 4.6 4 0 0 4 4 4 0 PQQ enzyme repeat AAA_18 PF13238.6 KII95974.1 - 0.089 13.3 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KII95975.1 - 2.2e-15 56.4 0.3 4.3e-15 55.5 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KII95975.1 - 3e-05 24.0 8.9 5.1e-05 23.3 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_AbiU2 PF18734.1 KII95975.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AbiU2 Nup160 PF11715.8 KII95976.1 - 3.7e-30 105.1 0.0 5.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Kinesin PF00225.23 KII95978.1 - 2.4e-108 362.0 0.0 3.9e-108 361.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 KII95978.1 - 5.1e-42 144.1 0.0 1.4e-41 142.7 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 KII95978.1 - 1.2e-40 139.5 6.2 2.5e-31 109.2 2.4 2.9 1 1 1 2 2 2 2 Kinesin-associated Microtub_bd PF16796.5 KII95978.1 - 6.9e-22 78.0 0.0 2e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KII95978.1 - 2e-11 44.3 0.0 4.3e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 PH domain FHA PF00498.26 KII95978.1 - 3.1e-07 30.6 0.0 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KII95978.1 - 1.1e-06 28.9 0.3 4.6e-06 27.0 0.3 2.1 1 0 0 1 1 1 1 Kinesin protein 1B EPOP PF15223.6 KII95978.1 - 0.15 11.4 5.4 0.31 10.4 5.4 1.4 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein PilJ PF13675.6 KII95978.1 - 3.7 7.6 7.3 7.9 6.5 0.2 3.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term EAP30 PF04157.16 KII95978.1 - 8.2 5.6 7.6 0.29 10.4 0.6 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family Ribosomal_S4 PF00163.19 KII95979.1 - 7.7e-12 46.0 0.5 1.2e-11 45.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KII95979.1 - 3.6e-10 39.4 0.0 6.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Presenilin PF01080.17 KII95980.1 - 1.6 7.4 3.1 2.5 6.8 3.1 1.5 1 0 0 1 1 1 0 Presenilin LIM_bind PF01803.16 KII95981.1 - 8.7e-55 185.9 0.0 1e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein zf-CCCH_4 PF18044.1 KII95982.1 - 3.5e-08 33.1 3.5 5.6e-08 32.4 3.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 KII95982.1 - 4.9e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 KII95982.1 - 2.2e-06 27.4 3.2 3.5e-06 26.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KII95982.1 - 3.6e-06 26.8 6.0 6.2e-06 26.1 6.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 KII95982.1 - 0.00071 20.2 0.2 0.0017 19.0 0.2 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 KII95982.1 - 1.5 9.4 4.6 2.4 8.8 4.6 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HMG_box PF00505.19 KII95983.1 - 4.5e-21 75.0 0.5 7.5e-21 74.3 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KII95983.1 - 5.6e-10 39.7 0.3 1.2e-09 38.6 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 KII95983.1 - 0.00039 20.6 1.1 0.0005 20.3 1.1 1.2 1 0 0 1 1 1 1 Protamine and protamine like CHDNT PF08073.12 KII95983.1 - 0.00049 20.0 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain Ccdc124 PF06244.12 KII95983.1 - 0.0014 19.2 1.1 0.0014 19.2 1.1 1.6 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 YABBY PF04690.13 KII95983.1 - 0.0022 18.6 1.1 0.0022 18.6 1.1 1.4 1 1 1 2 2 2 1 YABBY protein WW PF00397.26 KII95984.1 - 9.6e-08 32.0 2.8 1.8e-07 31.1 2.8 1.5 1 0 0 1 1 1 1 WW domain Cyt-b5 PF00173.28 KII95988.1 - 4e-11 42.9 0.2 7.2e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.19 KII95989.1 - 7.9e-36 122.9 0.5 2e-35 121.6 0.4 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KII95989.1 - 2.8e-15 56.1 0.1 1.9e-07 31.0 0.0 3.6 3 1 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M24 PF00557.24 KII95991.1 - 1.6e-55 188.0 0.1 2.2e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KII95991.1 - 9.9e-39 131.9 0.0 1.8e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EPSP_synthase PF00275.20 KII95991.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) AA_permease_2 PF13520.6 KII95992.1 - 1.3e-42 146.2 51.8 1.8e-42 145.7 51.8 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 KII95992.1 - 2.1e-33 115.5 0.0 3.8e-32 111.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AA_permease PF00324.21 KII95992.1 - 7.5e-23 80.9 40.3 1.1e-22 80.4 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease IF-2 PF11987.8 KII95992.1 - 1.9e-19 69.7 0.0 4.2e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KII95992.1 - 3.9e-16 59.2 3.7 2.8e-10 40.4 0.2 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KII95992.1 - 1e-06 28.8 0.0 7.8e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KII95992.1 - 5.6e-05 23.0 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KII95992.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Cwf_Cwc_15 PF04889.12 KII95992.1 - 0.0016 18.2 14.8 0.0016 18.2 14.8 3.6 3 1 1 4 4 2 1 Cwf15/Cwc15 cell cycle control protein ATP_bind_1 PF03029.17 KII95992.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KII95992.1 - 0.11 12.8 0.1 0.57 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 KII95993.1 - 1.7e-68 229.5 0.4 1.9e-68 229.3 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KII95993.1 - 1.6e-14 53.9 1.4 1.2e-08 34.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KII95993.1 - 9.2e-11 42.0 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KII95993.1 - 1.1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KII95993.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KII95993.1 - 7.7e-08 32.1 0.0 9.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KII95993.1 - 7.4e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KII95993.1 - 0.035 13.6 0.0 0.43 10.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KII95993.1 - 0.039 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KII95993.1 - 0.062 12.9 0.1 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KII95993.1 - 0.18 11.9 0.0 0.93 9.5 0.0 1.9 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.18 KII95993.1 - 0.2 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CMAS PF02353.20 KII95994.1 - 1.2e-57 195.3 0.0 1.6e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KII95994.1 - 4.1e-08 33.8 0.0 9.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KII95994.1 - 4.9e-06 27.1 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KII95994.1 - 0.00037 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KII95994.1 - 0.00054 19.8 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KII95994.1 - 0.0095 16.7 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KII95994.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DOT1 PF08123.13 KII95994.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 KII95994.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KII95994.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_S10 PF00450.22 KII95995.1 - 4.1e-75 253.8 1.4 7.7e-75 252.9 1.4 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase NCBP3 PF10309.9 KII95996.1 - 4.4e-11 42.4 0.0 8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KII95996.1 - 0.0006 20.3 8.9 0.0006 20.3 8.9 2.8 3 0 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 KH_8 PF17903.1 KII95997.1 - 3.9e-33 113.4 0.3 2.4e-32 110.8 0.0 2.2 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KII95997.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KII95997.1 - 0.03 14.2 0.2 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 KH domain EAF PF09816.9 KII95998.1 - 3.2e-25 88.4 0.0 6.7e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor PCEMA1 PF07418.11 KII95998.1 - 0.011 15.2 0.2 0.011 15.2 0.2 1.6 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 Ferritin_2 PF13668.6 KII95999.1 - 1.2e-32 113.0 0.7 1.9e-32 112.3 0.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain SPX PF03105.19 KII95999.1 - 0.051 13.5 4.4 0.061 13.2 4.4 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 KII95999.1 - 5.3 5.8 10.3 7.7 5.3 10.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S10 PF00450.22 KII96001.1 - 1.1e-102 344.6 0.1 1.3e-102 344.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Nop PF01798.18 KII96002.1 - 1.5e-85 286.3 0.1 3.2e-85 285.3 0.1 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KII96002.1 - 6.9e-19 68.0 0.2 6.9e-19 68.0 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SRP-alpha_N PF04086.13 KII96002.1 - 3.4 7.5 21.5 5.1 6.9 21.5 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal adh_short PF00106.25 KII96003.1 - 9.1e-06 25.3 0.0 0.27 10.7 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase ATP_bind_3 PF01171.20 KII96004.1 - 1e-17 64.5 0.1 1.8e-17 63.7 0.0 1.4 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 KII96004.1 - 7.4e-16 57.4 4.5 7.4e-16 57.4 4.5 3.7 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KII96004.1 - 0.037 12.8 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.6 KII96004.1 - 0.29 11.1 3.2 0.19 11.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) YyzF PF14116.6 KII96004.1 - 0.96 9.5 3.2 15 5.7 0.1 3.1 3 0 0 3 3 3 0 YyzF-like protein RecR PF02132.15 KII96004.1 - 4.3 7.0 11.6 0.082 12.5 1.1 3.3 4 0 0 4 4 4 0 RecR protein DUF2616 PF11077.8 KII96004.1 - 9 6.0 8.0 2.6 7.7 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) DUF2458 PF10454.9 KII96005.1 - 5.1e-09 36.0 1.3 1.2e-08 34.8 1.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 KII96005.1 - 0.015 15.0 0.3 0.026 14.2 0.3 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Abhydrolase_1 PF00561.20 KII96006.1 - 6.4e-11 42.4 0.1 1e-09 38.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII96006.1 - 7.4e-06 26.7 0.4 1.3e-05 26.0 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KII96006.1 - 0.00027 21.0 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein GDP_Man_Dehyd PF16363.5 KII96007.1 - 2.2e-59 201.6 0.0 2.8e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KII96007.1 - 2.8e-46 157.9 0.0 4.4e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KII96007.1 - 1.6e-09 37.2 0.0 3.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KII96007.1 - 4.1e-07 29.4 0.1 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KII96007.1 - 2.4e-06 26.8 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KII96007.1 - 4.5e-05 22.7 0.4 0.0083 15.3 0.2 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Bystin PF05291.11 KII96008.1 - 5.4e-125 416.5 0.0 7.1e-125 416.1 0.0 1.1 1 0 0 1 1 1 1 Bystin TrmO_C PF18389.1 KII96008.1 - 0.15 12.2 2.5 1 9.5 0.1 2.9 3 0 0 3 3 3 0 TrmO C-terminal domain Glyco_hydro_79C PF16862.5 KII96009.1 - 5.5e-09 36.9 0.3 1.3e-08 35.6 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Abhydrolase_6 PF12697.7 KII96010.1 - 3.3e-10 40.9 0.0 7.9e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KII96010.1 - 0.027 14.1 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold PUF PF00806.19 KII96011.1 - 4.9e-16 57.4 0.0 0.0002 20.9 0.0 6.7 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Katanin_con80 PF13925.6 KII96011.1 - 0.024 14.7 0.3 0.05 13.6 0.3 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Ribosomal_S11 PF00411.19 KII96012.1 - 6.3e-08 33.0 0.1 9.2e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 GTA_holin_3TM PF11351.8 KII96012.1 - 0.14 12.7 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Glyco_transf_8 PF01501.20 KII96013.1 - 1.7e-26 93.4 0.0 1.7e-25 90.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 KII96013.1 - 5.3e-19 69.2 0.1 2.5e-18 67.0 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Glyco_transf_24 PF18404.1 KII96013.1 - 6.5e-06 25.7 0.0 2.3e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Glucosyltransferase 24 Methyltransf_3 PF01596.17 KII96013.1 - 4.3e-05 22.8 0.0 8.7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Epimerase PF01370.21 KII96014.1 - 1.2e-41 142.8 0.0 1.7e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KII96014.1 - 9.1e-27 94.3 0.0 1.4e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KII96014.1 - 2.7e-14 52.9 0.0 4.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_2 PF00535.26 KII96014.1 - 4.4e-14 52.6 0.1 1.6e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KII96014.1 - 9.4e-07 28.9 0.3 4.3e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_10 PF13460.6 KII96014.1 - 1.5e-06 28.2 0.0 2.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KII96014.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KII96014.1 - 0.0002 20.6 0.0 0.0038 16.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KII96014.1 - 0.00033 20.3 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KII96014.1 - 0.016 14.3 0.0 0.97 8.5 0.4 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 KII96014.1 - 0.06 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 KR domain Glyco_tranf_2_2 PF10111.9 KII96014.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 adh_short PF00106.25 KII96014.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase SNF2_N PF00176.23 KII96015.1 - 4.8e-53 180.1 0.2 4.8e-46 157.1 0.0 2.6 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KII96015.1 - 1.3e-14 54.5 0.1 6.9e-14 52.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KII96015.1 - 7.1e-05 22.6 6.7 7.1e-05 22.6 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KII96015.1 - 0.00013 22.3 6.7 0.00013 22.3 6.7 2.9 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 KII96015.1 - 0.00016 21.9 2.9 0.00045 20.4 2.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain DEAD PF00270.29 KII96015.1 - 0.00023 21.0 0.0 0.00073 19.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KII96015.1 - 0.00026 21.0 0.0 0.00054 20.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-Nse PF11789.8 KII96015.1 - 0.00033 20.4 3.1 0.001 18.9 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 KII96015.1 - 0.00086 19.1 6.0 0.00086 19.1 6.0 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KII96015.1 - 0.0025 17.8 0.7 0.0025 17.8 0.7 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KII96015.1 - 0.0028 17.5 5.0 0.0028 17.5 5.0 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KII96015.1 - 0.021 14.9 0.8 0.021 14.9 0.8 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KII96015.1 - 0.097 12.6 1.1 0.24 11.3 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3523 PF12037.8 KII96015.1 - 0.98 8.7 9.3 9.8 5.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Acyl-CoA_dh_1 PF00441.24 KII96016.1 - 2.7e-27 95.8 0.3 3.7e-27 95.4 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KII96016.1 - 1.4e-17 63.6 0.2 2.7e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KII96016.1 - 3.8e-15 55.8 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KII96016.1 - 4.8e-12 46.5 0.0 1.5e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KII96016.1 - 0.0073 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 KII96018.1 - 2.7e-20 72.1 0.2 3.6e-20 71.7 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KII96018.1 - 2e-19 69.7 0.1 3.3e-19 69.0 0.1 1.3 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KII96018.1 - 0.00054 20.1 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KII96018.1 - 0.0038 17.3 1.5 0.042 13.9 1.4 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 KII96018.1 - 0.0068 16.5 0.0 0.009 16.1 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 KII96018.1 - 0.0079 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 KII96018.1 - 0.0086 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 KII96018.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 KII96018.1 - 0.031 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 KII96018.1 - 0.043 14.1 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 NAD2 PF18782.1 KII96018.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Inv-AAD PF18785.1 KII96018.1 - 0.097 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase IF3_C PF00707.22 KII96019.1 - 0.00019 21.3 0.1 0.00041 20.2 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 KII96019.1 - 0.0023 18.1 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain RasGAP_C PF03836.15 KII96019.1 - 0.88 9.7 4.7 0.5 10.5 0.4 2.6 3 2 0 3 3 3 0 RasGAP C-terminus PPR_2 PF13041.6 KII96020.1 - 3.2e-06 27.2 0.0 0.00012 22.2 0.0 3.5 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.6 KII96020.1 - 0.00026 21.0 0.1 0.002 18.2 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 KII96020.1 - 0.019 14.6 0.1 1.6 8.5 0.1 3.7 4 0 0 4 4 4 0 PPR repeat PPR PF01535.20 KII96020.1 - 0.5 10.7 1.7 1.1e+02 3.5 0.0 4.3 4 0 0 4 4 4 0 PPR repeat MIF4G_like_2 PF09090.11 KII96021.1 - 3.1e-75 253.1 0.0 4.2e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KII96021.1 - 1.9e-66 223.5 0.0 4e-66 222.4 0.0 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KII96021.1 - 0.00022 20.9 0.0 0.003 17.2 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain UAA PF08449.11 KII96022.1 - 1.6e-65 221.3 5.6 2e-65 221.0 5.6 1.0 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 KII96022.1 - 0.0025 17.1 3.7 0.006 15.8 3.7 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF3272 PF11676.8 KII96022.1 - 4.3 7.7 5.1 14 6.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Cyclin_N PF00134.23 KII96023.1 - 3.7e-14 52.6 0.2 6e-14 51.9 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KII96023.1 - 5.4e-09 36.6 0.1 5.4e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 Cyclin Alk_phosphatase PF00245.20 KII96023.1 - 0.009 15.0 0.4 0.012 14.6 0.4 1.2 1 0 0 1 1 1 1 Alkaline phosphatase TMEM174 PF15029.6 KII96023.1 - 0.39 10.4 1.8 0.76 9.4 1.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 SH3_9 PF14604.6 KII96024.1 - 3.8e-15 55.5 0.2 6.6e-15 54.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KII96024.1 - 2.1e-13 49.6 0.1 3.6e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KII96024.1 - 2.9e-11 42.9 0.0 4.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Suf PF05843.14 KII96026.1 - 6.1 6.7 7.5 6.7 6.6 7.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1840 PF08895.11 KII96027.1 - 0.029 14.7 0.5 0.063 13.6 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) F-box PF00646.33 KII96028.1 - 0.00015 21.5 0.1 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain Ribosomal_S14 PF00253.21 KII96028.1 - 1.2 8.9 6.5 0.16 11.8 1.6 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Ribosomal_L2_C PF03947.18 KII96029.1 - 3.4e-45 153.3 3.8 5.3e-45 152.7 3.8 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KII96029.1 - 1.5e-14 53.7 0.1 4.1e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4515 PF14988.6 KII96030.1 - 0.068 13.0 13.6 0.13 12.1 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF2458 PF10454.9 KII96030.1 - 0.31 10.7 6.8 0.44 10.2 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) BURP PF03181.15 KII96030.1 - 0.34 10.5 1.5 0.53 9.8 1.5 1.2 1 0 0 1 1 1 0 BURP domain FUSC PF04632.12 KII96030.1 - 0.95 7.9 11.5 2 6.8 11.5 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KII96030.1 - 8 6.9 18.2 0.9 10.0 13.6 1.7 2 0 0 2 2 2 0 Fez1 AAA_11 PF13086.6 KII96030.1 - 8 6.2 10.8 0.91 9.3 6.6 1.5 2 0 0 2 2 2 0 AAA domain Tti2 PF10521.9 KII96031.1 - 6.3e-39 134.2 0.0 1.2e-38 133.3 0.0 1.3 1 0 0 1 1 1 1 Tti2 family Ribosomal_S25 PF03297.15 KII96033.1 - 1.1e-39 134.7 0.4 1.2e-39 134.5 0.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 KII96033.1 - 0.0021 17.5 0.2 0.0038 16.8 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MerR PF00376.23 KII96033.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 MerR family regulatory protein PRKCSH-like PF12999.7 KII96034.1 - 3.9e-51 173.3 0.5 7.7e-51 172.4 0.5 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KII96034.1 - 1.6e-24 86.3 0.0 3.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KII96034.1 - 9.6e-09 36.1 0.3 2.8e-08 34.6 0.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein FGGY_C PF02782.16 KII96035.1 - 1.9e-46 158.3 0.1 2.6e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KII96035.1 - 5.1e-20 72.1 0.0 6.6e-19 68.4 0.0 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KII96035.1 - 5.3e-05 22.8 1.5 0.02 14.4 0.3 2.8 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DUF4460 PF14687.6 KII96035.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Peptidase_S9_N PF02897.15 KII96036.1 - 6.2e-91 305.2 1.9 8.6e-91 304.8 1.9 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KII96036.1 - 1.8e-53 181.2 0.0 3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Mito_carr PF00153.27 KII96037.1 - 8.3e-61 201.9 5.4 1.2e-21 76.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 KII96038.1 - 0.00036 20.4 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Dmrt1 PF12374.8 KII96039.1 - 3.3 8.2 6.8 14 6.2 0.0 2.6 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 DUF3525 PF12039.8 KII96040.1 - 0.2 10.4 0.2 0.26 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) WD40 PF00400.32 KII96041.1 - 3.9e-12 46.5 12.8 3.3e-06 27.7 1.6 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII96041.1 - 3.8e-05 23.9 0.0 1.7 9.0 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KII96041.1 - 0.014 15.2 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KII96041.1 - 0.021 12.8 0.0 0.24 9.3 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Cyclin PF08613.11 KII96042.1 - 2.8e-42 144.8 1.0 3.2e-42 144.6 1.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KII96042.1 - 0.08 12.7 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain adh_short_C2 PF13561.6 KII96044.1 - 6.9e-51 173.0 2.3 8.6e-51 172.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KII96044.1 - 9.6e-47 159.0 0.8 1.2e-46 158.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KII96044.1 - 9.1e-12 45.3 0.1 1.3e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KII96044.1 - 0.0004 19.8 0.1 0.00057 19.4 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 KII96044.1 - 0.0081 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LDcluster4 PF18306.1 KII96044.1 - 0.05 13.2 0.3 1.6 8.3 0.0 2.4 2 1 0 2 2 2 0 SLOG cluster4 family EF-hand_1 PF00036.32 KII96045.1 - 1.6e-28 96.1 9.3 4e-07 29.1 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KII96045.1 - 4e-24 84.9 5.9 1.3e-14 54.4 1.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KII96045.1 - 1.8e-22 77.3 5.4 1.4e-05 24.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KII96045.1 - 3.4e-18 64.3 11.9 2.8e-05 23.4 0.4 4.5 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KII96045.1 - 2.8e-13 49.5 11.3 0.0002 21.2 0.2 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KII96045.1 - 2.9e-06 27.2 6.1 0.0019 18.1 0.6 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KII96045.1 - 6.8e-06 26.4 0.0 0.013 15.8 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KII96045.1 - 0.019 15.3 0.2 2.6 8.4 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 KII96045.1 - 0.16 12.2 0.8 1.7 8.9 0.5 2.7 2 2 1 3 3 3 0 Dockerin type I domain MnmE_helical PF12631.7 KII96046.1 - 1.8e-43 149.1 0.0 2.3e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KII96046.1 - 6e-37 126.5 0.0 3.5e-36 124.0 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KII96046.1 - 8.4e-18 64.5 0.0 1.8e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KII96046.1 - 3.4e-05 24.0 0.0 0.00013 22.1 0.0 2.0 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KII96046.1 - 0.00047 19.7 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KII96046.1 - 0.054 14.0 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KII96046.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KII96048.1 - 4.4e-06 27.3 14.5 0.0015 19.3 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII96048.1 - 0.14 12.5 0.8 16 5.9 0.2 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SUR7 PF06687.12 KII96051.1 - 0.91 9.1 15.3 0.82 9.3 0.4 2.3 2 0 0 2 2 2 0 SUR7/PalI family MBOAT PF03062.19 KII96053.1 - 2e-46 159.0 4.3 2.7e-46 158.5 2.0 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L18 PF17135.4 KII96054.1 - 1.2e-89 298.7 1.7 1.3e-89 298.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KII96054.1 - 0.0014 19.3 0.0 0.0014 19.3 0.0 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RRM_1 PF00076.22 KII96055.1 - 6.9e-18 64.2 0.0 9.1e-18 63.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KII96055.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KII96055.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif GN3L_Grn1 PF08701.11 KII96056.1 - 1e-21 76.8 12.9 1e-21 76.8 12.9 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KII96056.1 - 1e-14 54.6 0.2 1.3e-12 47.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KII96056.1 - 9.3e-09 35.4 0.1 8.9e-07 29.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KII96056.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KII96056.1 - 0.0004 20.5 0.5 0.0004 20.5 0.5 3.3 2 2 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KII96056.1 - 0.00069 19.2 0.4 0.023 14.2 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KII96056.1 - 0.0066 16.0 0.3 3.6 7.1 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KII96056.1 - 0.0078 16.6 3.2 0.075 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain YL1 PF05764.13 KII96056.1 - 0.013 15.6 11.5 0.013 15.6 11.5 3.0 2 1 0 2 2 1 0 YL1 nuclear protein SRPRB PF09439.10 KII96056.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 KII96056.1 - 0.04 13.0 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 KII96056.1 - 0.044 13.4 0.6 1.4 8.5 0.0 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KII96056.1 - 0.045 14.0 0.0 8.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KII96056.1 - 0.063 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin TniQ PF06527.11 KII96056.1 - 0.13 13.0 0.0 0.32 11.7 0.0 1.7 1 0 0 1 1 1 0 TniQ Lin-8 PF03353.15 KII96056.1 - 4.5 6.7 10.6 0.034 13.7 1.5 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist F-box-like PF12937.7 KII96057.1 - 4e-07 29.8 0.5 1.4e-06 28.1 0.5 2.0 1 0 0 1 1 1 1 F-box-like ADH_zinc_N_2 PF13602.6 KII96059.1 - 0.0067 17.5 0.0 0.016 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase JmjC PF02373.22 KII96060.1 - 1.4e-14 54.5 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KII96060.1 - 0.00023 21.0 0.0 0.0041 16.9 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.22 KII96060.1 - 0.007 16.2 2.9 0.016 15.0 2.9 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KII96060.1 - 0.016 15.3 1.5 0.035 14.2 1.5 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Cupin_2 PF07883.11 KII96060.1 - 0.66 9.7 0.0 0.66 9.7 0.0 2.0 2 0 0 2 2 2 0 Cupin domain FYVE PF01363.21 KII96060.1 - 0.84 9.8 12.8 0.036 14.2 6.1 2.2 3 0 0 3 3 3 0 FYVE zinc finger Prok-RING_2 PF14445.6 KII96060.1 - 7.1 6.9 16.3 0.095 12.9 4.1 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 Response_reg PF00072.24 KII96061.1 - 5.7e-22 78.0 0.1 2.4e-16 59.9 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.19 KII96061.1 - 8.8e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase DUF3546 PF12066.8 KII96062.1 - 1.5e-11 44.5 0.1 5.8e-11 42.6 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KII96062.1 - 1.7e-08 35.1 12.3 1.7e-08 35.1 12.3 3.0 2 1 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KII96062.1 - 0.00061 19.5 1.1 0.0014 18.4 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 KII96062.1 - 0.074 13.4 2.7 0.4 11.1 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 KII96062.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.26 KII96062.1 - 0.25 11.9 4.5 0.23 12.0 1.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_1 PF00076.22 KII96063.1 - 9.3e-05 22.2 0.0 0.013 15.3 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ROKNT PF08067.11 KII96063.1 - 0.13 12.6 2.3 0.27 11.6 1.6 1.9 1 1 1 2 2 2 0 ROKNT (NUC014) domain Lipase_3 PF01764.25 KII96064.1 - 4.7e-16 58.9 0.0 1.5e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KII96064.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KII96064.1 - 0.39 11.3 3.8 0.92 10.1 3.8 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family PDH PF02153.17 KII96065.1 - 2.4e-13 49.7 0.0 3.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KII96065.1 - 2e-06 28.0 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KII96065.1 - 8.9e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KII96065.1 - 0.0019 17.8 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KII96065.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 KII96065.1 - 0.0096 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.18 KII96065.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KII96065.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Spt4 PF06093.13 KII96066.1 - 1.4e-29 102.0 0.2 1.7e-29 101.7 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Ecotin PF03974.13 KII96067.1 - 0.0084 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Ecotin MFS_1 PF07690.16 KII96068.1 - 1.2e-31 110.0 39.1 3.1e-31 108.6 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KII96068.1 - 1.3e-10 40.7 24.7 2e-10 40.2 24.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF423 PF04241.15 KII96068.1 - 1.6 9.0 8.1 0.16 12.2 2.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF423) p450 PF00067.22 KII96069.1 - 4.4e-64 216.9 0.0 3.7e-56 190.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Med13_C PF06333.12 KII96070.1 - 7.4e-54 183.2 4.8 7.4e-54 183.2 4.8 3.6 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KII96070.1 - 2.3e-53 181.6 1.0 2.3e-53 181.6 1.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MerR PF00376.23 KII96070.1 - 0.031 14.0 0.0 0.098 12.4 0.0 1.9 1 0 0 1 1 1 0 MerR family regulatory protein Abhydro_lipase PF04083.16 KII96072.1 - 7e-18 64.0 0.0 1.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KII96072.1 - 1e-08 35.2 0.3 2e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KII96072.1 - 5e-07 30.6 3.3 5e-07 30.6 3.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KII96072.1 - 7e-07 28.7 0.0 2.5e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 S36_mt PF10937.8 KII96074.1 - 3.7e-13 51.1 5.3 1.3e-07 33.2 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial Proteasome PF00227.26 KII96075.1 - 4.2e-47 160.1 0.4 1.6e-46 158.2 0.4 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KII96075.1 - 1.1e-14 53.8 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_1 PF04997.12 KII96076.1 - 2.2e-85 286.7 0.0 3.3e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KII96076.1 - 2.5e-82 276.3 0.2 3.8e-82 275.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KII96076.1 - 1.3e-71 240.2 0.0 2.8e-71 239.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KII96076.1 - 2e-38 131.8 0.0 7e-37 126.8 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KII96076.1 - 1.5e-32 111.7 0.0 3.4e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Mito_carr PF00153.27 KII96077.1 - 6.5e-46 154.2 6.7 8.3e-19 67.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KII96077.1 - 0.022 13.9 0.2 0.92 8.6 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Acyl-CoA_dh_1 PF00441.24 KII96078.1 - 3.5e-43 147.4 2.0 5.8e-43 146.7 2.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KII96078.1 - 1.2e-27 96.9 0.2 7.3e-27 94.3 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KII96078.1 - 1.5e-22 79.6 0.1 4.7e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KII96078.1 - 7.7e-20 71.5 0.2 1.2e-19 70.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KII96078.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal DUF2433 PF10360.9 KII96079.1 - 1.7e-47 160.6 0.4 4e-47 159.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 KII96079.1 - 0.00021 21.1 0.1 0.0004 20.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KII96079.1 - 0.092 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase CDC27 PF09507.10 KII96079.1 - 0.25 10.7 12.3 0.47 9.8 12.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cytomega_UL84 PF06284.11 KII96079.1 - 0.29 9.6 5.5 0.41 9.0 4.9 1.4 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein NARP1 PF12569.8 KII96079.1 - 0.41 9.5 6.8 0.64 8.9 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rrn6 PF10214.9 KII96079.1 - 0.99 7.8 4.0 1.8 6.9 4.0 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SRP-alpha_N PF04086.13 KII96079.1 - 9.4 6.1 10.8 20 5.0 10.8 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GDI PF00996.18 KII96080.1 - 3.9e-38 131.1 0.0 9e-38 129.9 0.0 1.6 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KII96080.1 - 0.0069 16.6 0.1 0.034 14.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.22 KII96081.1 - 1.7e-42 143.1 0.0 9.2e-23 79.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KII96081.1 - 2.6e-05 24.2 0.1 0.38 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KII96081.1 - 0.0036 17.3 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DTHCT PF08070.11 KII96081.1 - 0.023 15.4 26.3 0.023 15.4 26.3 4.7 1 1 3 4 4 4 0 DTHCT (NUC029) region RRM_5 PF13893.6 KII96081.1 - 0.025 14.2 0.0 0.088 12.4 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ric8 PF10165.9 KII96082.1 - 2.7e-117 392.6 0.0 3.2e-117 392.4 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.9 KII96083.1 - 1.5e-19 70.1 0.0 2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 KII96083.1 - 0.031 14.6 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 PIN domain KIAA1430 PF13879.6 KII96083.1 - 0.09 13.5 0.0 0.11 13.2 0.0 1.2 1 0 0 1 1 1 0 KIAA1430 homologue PMI_typeI PF01238.21 KII96085.1 - 1.6e-118 396.1 0.0 1.9e-118 395.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KII96085.1 - 0.06 13.1 0.1 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Cupin domain TFIIA PF03153.13 KII96086.1 - 2.5 8.0 8.1 3.2 7.7 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM171 PF15471.6 KII96090.1 - 6.2 5.7 17.4 1.8 7.4 1.2 3.2 3 0 0 3 3 3 0 Transmembrane protein family 171 PvlArgDC PF01862.16 KII96091.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF1993 PF09351.10 KII96093.1 - 0.046 13.9 2.3 0.1 12.7 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) baeRF_family2 PF18844.1 KII96093.1 - 0.1 12.7 4.5 0.43 10.6 3.1 2.1 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Atg14 PF10186.9 KII96093.1 - 0.16 11.0 3.2 0.24 10.4 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KII96093.1 - 0.48 11.0 6.3 0.71 10.4 6.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 KII96093.1 - 0.78 8.2 5.7 1.1 7.7 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 KII96093.1 - 1 9.4 9.3 1.6 8.8 9.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding WD40 PF00400.32 KII96096.1 - 1.5e-14 54.1 10.3 3.6e-09 37.1 0.2 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KII96096.1 - 2.7e-05 24.4 0.0 0.073 13.4 0.0 3.9 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KII96096.1 - 0.011 14.7 0.1 6.5 5.6 0.0 2.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Retrotran_gag_2 PF14223.6 KII96102.1 - 1.8e-08 34.1 0.0 2e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 KII96103.1 - 0.0054 16.7 3.1 0.01 15.8 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 KII96103.1 - 0.022 15.2 0.1 0.041 14.3 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 KII96103.1 - 1.6 8.5 6.7 3.6 7.4 6.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Lzipper-MIP1 PF14389.6 KII96109.1 - 0.087 13.1 0.5 0.23 11.8 0.5 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 ABC_tran_Xtn PF12848.7 KII96109.1 - 2 8.5 8.1 3.4 7.8 2.6 3.1 3 0 0 3 3 3 0 ABC transporter Transpos_assoc PF13963.6 KII96112.1 - 0.23 11.8 0.1 0.42 11.0 0.1 1.3 1 0 0 1 1 1 0 Transposase-associated domain PPR_2 PF13041.6 KII96119.1 - 5.8e-46 154.5 1.5 7.8e-11 42.0 0.0 13.4 9 3 4 13 13 13 8 PPR repeat family PPR PF01535.20 KII96119.1 - 1.4e-35 119.0 5.4 0.00011 22.2 0.0 14.5 16 0 0 16 16 15 6 PPR repeat PPR_3 PF13812.6 KII96119.1 - 4.4e-27 93.9 0.0 8e-08 32.2 0.0 8.9 9 2 0 10 10 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KII96119.1 - 7.8e-27 92.7 4.0 4.8e-06 26.2 0.0 10.2 11 0 0 11 11 11 4 PPR repeat PPR_long PF17177.4 KII96119.1 - 2.5e-17 62.9 4.6 3.4e-11 42.9 0.3 5.6 5 0 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KII96119.1 - 1.7e-08 34.6 3.5 0.75 10.8 0.0 9.9 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII96119.1 - 0.0071 16.5 7.5 0.42 11.0 0.0 6.1 8 0 0 8 8 8 1 Tetratricopeptide repeat COX5A PF02284.16 KII96119.1 - 0.03 14.3 0.1 23 5.0 0.0 4.1 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va Clathrin PF00637.20 KII96119.1 - 0.11 12.3 0.0 0.56 10.1 0.0 2.3 1 0 0 1 1 1 0 Region in Clathrin and VPS Mito_fiss_reg PF05308.11 KII96119.1 - 0.16 12.0 1.4 0.36 10.9 1.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator TPR_12 PF13424.6 KII96119.1 - 2.8 8.3 9.6 9.3 6.6 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Coilin_N PF15862.5 KII96121.1 - 1.3e-12 47.7 1.0 1.3e-12 47.7 1.0 2.4 2 0 0 2 2 2 1 Coilin N-terminus CDC45 PF02724.14 KII96121.1 - 0.037 12.3 4.9 0.047 12.0 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 KII96121.1 - 0.06 11.1 7.2 0.082 10.7 7.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 KII96121.1 - 2.7 6.0 7.7 3.8 5.5 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 KII96121.1 - 8.4 4.4 12.3 13 3.8 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DnaJ PF00226.31 KII96122.1 - 3.2e-15 56.0 0.1 7.6e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KII96122.1 - 2e-14 53.4 0.0 3.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Thioredoxin PF00085.20 KII96123.1 - 1.2e-45 153.7 0.6 9.2e-24 83.4 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KII96123.1 - 2.8e-17 63.2 0.0 2.1e-11 44.0 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KII96123.1 - 4.4e-06 26.3 1.1 0.15 11.3 0.0 3.6 3 1 0 3 3 3 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KII96123.1 - 1.8e-05 25.0 0.0 0.03 14.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KII96123.1 - 0.0028 17.7 0.0 0.83 9.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Disulph_isomer PF06491.11 KII96123.1 - 0.075 13.1 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 Disulphide isomerase Thioredoxin_2 PF13098.6 KII96123.1 - 0.075 13.5 0.8 3.4 8.1 0.1 3.3 3 1 0 3 3 3 0 Thioredoxin-like domain AhpC-TSA PF00578.21 KII96123.1 - 0.17 11.8 0.2 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_4 PF13462.6 KII96123.1 - 0.2 11.8 0.6 6.4 6.9 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin zf-C2H2_4 PF13894.6 KII96123.1 - 0.21 12.5 2.4 0.87 10.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CGI-121 PF08617.10 KII96124.1 - 2.1e-52 177.5 0.2 2.4e-52 177.3 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Actino_peptide PF14408.6 KII96126.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomally synthesised peptide in actinomycetes DUF903 PF06004.12 KII96126.1 - 0.054 13.4 1.0 0.082 12.8 1.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) DUF903 PF06004.12 KII96127.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) VWA_2 PF13519.6 KII96128.1 - 1.1e-25 90.3 0.3 6.4e-25 87.9 0.2 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 KII96128.1 - 8.1e-11 41.1 22.9 3.5e-05 23.4 1.4 4.2 4 0 0 4 4 4 3 Ubiquitin interaction motif VWA PF00092.28 KII96128.1 - 8.9e-10 39.1 0.5 1.4e-09 38.4 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KII96128.1 - 2.1e-08 34.2 0.1 3.4e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like RAP80_UIM PF18282.1 KII96128.1 - 0.004 16.9 2.3 0.004 16.9 2.3 2.8 3 0 0 3 3 3 1 RAP80 N-terminal ubiquitin interaction motif Amidase PF01425.21 KII96131.1 - 3.6e-70 237.2 0.3 7.4e-68 229.5 0.2 2.1 2 0 0 2 2 2 2 Amidase CLP1_P PF16575.5 KII96132.1 - 1.5e-35 122.7 0.0 4e-35 121.3 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KII96132.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 KII96132.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KII96132.1 - 0.04 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KII96132.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ORC6 PF05460.13 KII96132.1 - 1.4 8.1 5.1 2.1 7.5 5.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WGG PF10273.9 KII96133.1 - 3.8e-23 81.9 0.2 6.9e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KII96133.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MFS_1 PF07690.16 KII96134.1 - 1.7e-24 86.4 15.9 1.7e-24 86.4 15.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FxsA PF04186.13 KII96135.1 - 0.023 14.8 0.1 0.042 14.0 0.1 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Cyclin_N PF00134.23 KII96136.1 - 2.7e-11 43.3 0.3 1.9e-10 40.5 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KII96136.1 - 0.002 18.2 0.3 0.08 13.0 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 KII96136.1 - 0.0087 16.4 0.1 0.039 14.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 KII96136.1 - 0.017 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Ldh_1_C PF02866.18 KII96137.1 - 4.9e-46 156.7 0.0 9.6e-46 155.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KII96137.1 - 2.3e-42 144.4 0.2 3.2e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KII96137.1 - 0.0034 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 KII96137.1 - 0.042 13.4 0.2 1 8.9 0.1 2.1 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 KII96137.1 - 0.042 14.3 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KII96137.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cyclin_N2 PF16500.5 KII96138.1 - 0.066 14.0 1.8 0.1 13.3 1.8 1.3 1 0 0 1 1 1 0 N-terminal region of cyclin_N TPR_12 PF13424.6 KII96141.1 - 6.4e-09 36.0 9.7 0.0042 17.3 0.1 5.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KII96141.1 - 3.3e-07 29.9 5.9 0.0066 16.5 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 KII96141.1 - 2.2e-06 27.2 1.7 0.0013 18.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KII96141.1 - 0.00045 20.2 1.8 0.17 12.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KII96141.1 - 0.0093 16.0 3.0 3.6 7.7 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KII96141.1 - 0.013 15.9 2.5 2 9.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AIMP2_LysRS_bd PF16780.5 KII96141.1 - 0.036 13.8 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain DUF627 PF04781.12 KII96141.1 - 0.091 12.8 1.3 12 6.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) RPN1_RPN2_N PF17781.1 KII96141.1 - 0.14 11.6 0.3 1.4 8.3 0.1 2.3 2 0 0 2 2 2 0 RPN1/RPN2 N-terminal domain ANAPC3 PF12895.7 KII96141.1 - 0.47 10.7 5.8 17 5.7 0.0 4.5 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KII96141.1 - 1.8 7.9 11.9 0.43 9.9 0.2 3.2 4 0 0 4 4 4 0 MalT-like TPR region TPR_6 PF13174.6 KII96141.1 - 2.7 8.8 7.4 3.2 8.6 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII96141.1 - 5.7 8.0 5.9 3.8 8.6 0.1 3.9 4 1 0 4 4 2 0 Tetratricopeptide repeat Ifi-6-16 PF06140.13 KII96142.1 - 0.00049 19.9 19.8 0.00049 19.9 19.8 2.0 2 0 0 2 2 2 1 Interferon-induced 6-16 family PMT PF02366.18 KII96143.1 - 2.5e-82 276.2 11.6 4.8e-82 275.2 11.6 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KII96143.1 - 4.7e-66 222.2 12.9 4.7e-66 222.2 12.9 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KII96143.1 - 7.3e-41 140.1 1.6 1.2e-40 139.3 1.6 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KII96143.1 - 1.7e-05 25.1 8.1 1.7e-05 25.1 8.1 3.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 KII96143.1 - 0.4 11.3 1.8 9.7 6.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Pyr_redox_2 PF07992.14 KII96145.1 - 1.6e-13 50.6 0.0 4.8e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KII96145.1 - 3.2e-12 46.2 0.0 7.8e-10 38.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KII96145.1 - 1e-11 44.0 0.0 2.1e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 KII96145.1 - 1.2e-09 38.3 4.4 0.00014 21.6 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KII96145.1 - 8.2e-09 35.6 6.2 0.028 14.4 0.1 4.0 3 1 0 4 4 4 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KII96145.1 - 1.5e-08 34.3 0.0 6.7e-06 25.6 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KII96145.1 - 3e-07 30.6 1.2 2.6e-05 24.3 0.0 3.7 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KII96145.1 - 9.5e-07 28.4 0.0 0.52 9.5 0.0 3.3 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KII96145.1 - 3.7e-05 23.8 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KII96145.1 - 7.5e-05 23.2 0.1 0.0029 18.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KII96145.1 - 0.00017 20.5 0.6 0.53 8.9 0.0 3.3 4 0 0 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 KII96145.1 - 0.0027 16.8 2.3 0.71 8.9 0.1 3.3 4 0 0 4 4 4 2 Lycopene cyclase protein Glu_dehyd_C PF16912.5 KII96145.1 - 0.0092 15.5 0.1 0.031 13.8 0.0 1.9 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 KII96145.1 - 0.025 13.8 0.1 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 KII96145.1 - 0.044 13.4 0.2 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KII96145.1 - 0.05 12.7 0.5 0.38 9.8 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 KII96145.1 - 0.12 11.6 0.4 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 KII96145.1 - 0.24 9.9 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 KII96145.1 - 0.31 10.1 0.1 11 4.9 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Cpn60_TCP1 PF00118.24 KII96147.1 - 6.9e-147 490.0 14.6 7.9e-147 489.8 14.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1366 PF07104.11 KII96147.1 - 0.054 13.2 0.1 0.21 11.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) CRM1_repeat PF18777.1 KII96147.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glyco_hydro_28 PF00295.17 KII96148.1 - 9.6e-48 162.9 5.5 1.2e-47 162.6 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 KII96148.1 - 8.1e-08 32.4 10.6 8.4e-07 29.0 7.3 2.3 1 1 1 2 2 2 2 Pectate lyase superfamily protein Glyco_hydro_28 PF00295.17 KII96149.1 - 2.5e-48 164.8 8.3 3.1e-48 164.5 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RA PF00788.23 KII96150.1 - 9e-10 39.1 3.0 2.8e-08 34.3 0.0 3.6 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KII96150.1 - 3.9e-06 26.4 0.3 2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KII96150.1 - 0.0012 18.7 0.1 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Ifi-6-16 PF06140.13 KII96151.1 - 0.0015 18.4 8.0 0.002 18.0 8.0 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Oxidored_q3 PF00499.20 KII96151.1 - 1.3 8.7 14.3 1.7 8.4 14.3 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DPBB_1 PF03330.18 KII96152.1 - 0.01 16.1 0.1 0.016 15.5 0.1 1.6 1 1 0 1 1 1 0 Lytic transglycolase Thaumatin PF00314.17 KII96153.1 - 3.2e-70 236.1 13.3 3.7e-70 235.9 13.3 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KII96153.1 - 0.00065 19.1 0.2 0.0014 18.0 0.0 1.6 2 0 0 2 2 2 1 Beta-1,3-glucanase Npa1 PF11707.8 KII96154.1 - 5.5e-110 367.9 0.9 3.6e-109 365.2 0.1 2.6 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KII96154.1 - 1.5e-49 168.3 1.1 5.1e-49 166.6 1.1 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 KII96154.1 - 0.17 12.6 0.0 0.66 10.7 0.0 2.0 1 0 0 1 1 1 0 Creb binding CDC45 PF02724.14 KII96154.1 - 0.21 9.8 2.3 0.32 9.3 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.7 KII96155.1 - 2.7e-12 47.8 1.9 3.7e-12 47.3 1.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pec_lyase_C PF00544.19 KII96156.1 - 3.5e-36 124.8 8.7 4.9e-36 124.3 8.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KII96156.1 - 0.00048 20.0 14.0 0.017 15.0 14.0 2.3 1 1 0 1 1 1 1 Right handed beta helix region YrhC PF14143.6 KII96157.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.7 1 1 1 2 2 2 0 YrhC-like protein Rsa3 PF14615.6 KII96158.1 - 2.1e-16 59.2 0.1 2.9e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Cwf_Cwc_15 PF04889.12 KII96158.1 - 0.023 14.4 4.7 0.048 13.4 4.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 KII96158.1 - 0.12 11.2 4.5 0.12 11.2 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 KII96158.1 - 0.44 9.3 10.2 0.52 9.1 10.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4551 PF15087.6 KII96158.1 - 1.4 7.7 11.1 1.6 7.5 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Macoilin PF09726.9 KII96158.1 - 1.6 7.2 7.2 1.6 7.2 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 KII96158.1 - 4.4 6.0 5.6 4.8 5.9 5.6 1.1 1 0 0 1 1 1 0 Presenilin AIRC PF00731.20 KII96159.1 - 6.2e-63 210.8 1.9 9.4e-63 210.2 0.4 2.0 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KII96159.1 - 8.6e-61 204.5 0.0 1.3e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KII96159.1 - 1.9e-20 72.3 0.0 3.7e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KII96159.1 - 7.2e-06 25.6 0.0 1.8e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KII96159.1 - 0.0018 17.9 0.0 0.022 14.3 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 KII96159.1 - 0.014 14.8 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 KII96159.1 - 0.046 14.2 0.2 70 4.0 0.0 3.5 2 1 1 3 3 3 0 CoA binding domain PrpR_N PF06506.11 KII96159.1 - 0.063 12.9 0.2 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Propionate catabolism activator ATP-grasp_3 PF02655.14 KII96159.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SCO1-SenC PF02630.14 KII96160.1 - 1.8e-44 150.9 0.0 2.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KII96160.1 - 8.3e-06 25.7 0.0 0.00011 22.1 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KII96160.1 - 9.7e-05 22.6 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like LCAT PF02450.15 KII96161.1 - 8e-80 268.9 0.3 1.7e-72 244.8 0.2 2.0 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 KII96161.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) NDUF_B7 PF05676.13 KII96162.1 - 7.6e-32 108.8 2.2 8.9e-32 108.6 2.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KII96162.1 - 0.011 15.8 0.9 0.015 15.3 0.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Bac_rhamnosid6H PF17389.2 KII96164.1 - 2.3e-15 56.7 0.3 3.9e-15 55.9 0.3 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KII96164.1 - 3.5e-07 29.9 0.0 8.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KII96164.1 - 1.6e-05 24.0 0.7 2.3e-05 23.5 0.7 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KII96164.1 - 0.021 13.5 0.5 0.034 12.8 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF608 PF04685.13 KII96164.1 - 0.03 13.5 1.1 0.047 12.9 1.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region GD_AH_C PF04295.13 KII96167.1 - 0.041 12.7 0.1 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Wzy_C PF04932.15 KII96167.1 - 0.25 11.0 7.6 0.33 10.6 1.4 2.4 2 0 0 2 2 2 0 O-Antigen ligase SPC25 PF06703.11 KII96167.1 - 1.4 8.7 5.0 0.37 10.6 2.0 1.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) AA_permease_2 PF13520.6 KII96168.1 - 6.6e-78 262.4 34.6 8.3e-78 262.1 34.6 1.1 1 0 0 1 1 1 1 Amino acid permease TPR_12 PF13424.6 KII96170.1 - 6.3e-17 61.6 43.3 3.2e-07 30.5 5.2 8.6 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 KII96170.1 - 8.4e-08 31.9 39.6 0.00015 21.5 2.4 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KII96170.1 - 1.4e-06 27.9 5.6 0.033 14.0 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KII96170.1 - 0.00022 21.1 19.3 0.14 12.3 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KII96170.1 - 0.00044 20.3 5.8 6.6 7.2 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 KII96170.1 - 0.00055 20.0 11.0 0.18 11.8 0.4 4.2 3 1 1 4 4 4 2 Domain of Unknown Function (DUF3856) Calici_MSP PF05752.11 KII96170.1 - 0.14 12.0 0.4 3.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Calicivirus minor structural protein Polyketide_cyc2 PF10604.9 KII96171.1 - 6.5e-06 26.5 0.7 2.7e-05 24.4 0.4 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KII96171.1 - 0.071 13.3 0.5 0.088 13.0 0.5 1.5 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.23 KII96172.1 - 6.6e-27 94.0 2.0 1.1e-26 93.3 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KII96172.1 - 5.2e-05 23.2 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF2235 PF09994.9 KII96173.1 - 6.7e-90 301.3 0.0 9.7e-90 300.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KII96173.1 - 0.0019 18.2 0.0 0.84 9.5 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal An_peroxidase PF03098.15 KII96174.1 - 7.3e-36 123.8 0.0 1.1e-26 93.5 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KII96174.1 - 5e-07 28.8 0.0 1.3e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Asp23 PF03780.13 KII96174.1 - 0.15 12.5 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Asp23 family, cell envelope-related function UPRTase PF14681.6 KII96175.1 - 1.7e-76 256.3 0.0 2e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KII96175.1 - 0.0024 17.4 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EMG1 PF03587.14 KII96176.1 - 3.2e-75 252.1 0.0 3.9e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase CRAL_TRIO PF00650.20 KII96177.1 - 8.9e-36 123.0 0.0 1.3e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KII96177.1 - 8.5e-12 45.1 0.3 1.9e-11 44.0 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KII96177.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Ig_5 PF16681.5 KII96178.1 - 0.021 15.2 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF4662 PF15578.6 KII96178.1 - 0.15 11.8 1.1 0.28 11.0 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) zf-BED PF02892.15 KII96178.1 - 0.21 11.6 7.2 1.4 9.0 2.3 2.9 2 0 0 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.11 KII96178.1 - 0.24 11.4 1.9 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TPR_12 PF13424.6 KII96179.1 - 6.8e-22 77.6 28.0 2.5e-06 27.7 2.8 8.0 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 KII96179.1 - 8.2e-17 60.5 18.6 0.011 15.5 0.1 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KII96179.1 - 1.5e-11 43.4 10.9 0.69 10.2 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 KII96179.1 - 1.1e-07 32.0 9.9 0.021 14.9 2.4 4.9 3 2 1 4 4 4 2 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 KII96179.1 - 2.4e-07 30.3 8.2 7.9 6.5 0.2 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 KII96179.1 - 5.3e-05 23.6 13.5 0.19 12.2 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KII96179.1 - 0.0016 18.5 3.3 4.8 7.2 0.2 4.2 3 2 0 4 4 4 1 Putative TPR-like repeat TPR_8 PF13181.6 KII96179.1 - 0.0023 18.0 8.6 45 4.6 0.1 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII96179.1 - 0.0034 18.1 18.7 2 9.5 0.1 8.6 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 KII96179.1 - 0.0037 17.8 5.9 25 5.8 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat DHR10 PF18595.1 KII96179.1 - 0.0047 17.0 4.4 0.08 13.0 0.0 4.0 4 0 0 4 4 4 1 Designed helical repeat protein 10 domain HicB_lk_antitox PF15919.5 KII96179.1 - 0.017 15.2 1.3 18 5.5 0.1 4.8 4 1 1 5 5 5 0 HicB_like antitoxin of bacterial toxin-antitoxin system TACC_C PF05010.14 KII96179.1 - 0.13 12.0 0.3 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF627 PF04781.12 KII96179.1 - 0.39 10.7 6.9 3.2 7.8 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 KII96179.1 - 1.8 8.8 17.3 12 6.2 0.2 5.4 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KII96179.1 - 2.2 9.0 18.6 12 6.7 0.1 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat SnoaL_2 PF12680.7 KII96180.1 - 0.044 14.4 0.1 0.061 14.0 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain Actin PF00022.19 KII96182.1 - 4.4e-146 486.6 0.0 2.7e-145 484.1 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KII96182.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_2 PF12796.7 KII96183.1 - 1.9e-05 25.2 0.0 0.0026 18.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KII96183.1 - 0.00065 20.2 0.1 0.1 13.2 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KII96183.1 - 0.00081 19.6 0.2 4.1 7.9 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KII96183.1 - 0.0094 16.4 0.1 48 5.0 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat F-box-like_2 PF13013.6 KII96184.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.7 KII96184.1 - 0.0059 16.5 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 F-box-like MIase PF02426.16 KII96184.1 - 0.024 14.8 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 0 Muconolactone delta-isomerase Plavaka PF18759.1 KII96186.1 - 2.2e-128 428.1 0.0 2.9e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 Plavaka transposase DUF3040 PF11239.8 KII96188.1 - 3.1 8.1 5.7 3.7 7.9 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) MISS PF15822.5 KII96190.1 - 0.0088 15.9 6.2 0.0088 15.9 6.2 2.2 2 0 0 2 2 2 1 MAPK-interacting and spindle-stabilising protein-like Actin PF00022.19 KII96191.1 - 6.9e-145 482.7 0.0 2.8e-144 480.7 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 KII96192.1 - 6.8e-123 410.3 0.1 1.3e-118 396.2 0.1 3.0 1 1 0 1 1 1 1 Actin zf-MYND PF01753.18 KII96193.1 - 1.1e-09 38.3 11.7 2e-09 37.4 11.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KII96193.1 - 7.4 7.0 13.5 1.6 9.1 9.8 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DcpS_C PF11969.8 KII96194.1 - 6.3e-12 46.0 0.2 2.1e-10 41.1 0.2 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Solute_trans_a PF03619.16 KII96195.1 - 1.3e-86 290.5 11.2 1.5e-86 290.2 11.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4389 PF14333.6 KII96195.1 - 0.37 10.7 7.9 0.23 11.4 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) TssN PF17555.2 KII96195.1 - 7.3 5.9 11.0 0.21 10.9 1.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN HD PF01966.22 KII96196.1 - 3.6e-13 49.8 0.4 7.1e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 HD domain HRI1 PF16815.5 KII96197.1 - 1.7e-24 86.8 0.1 2.2e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Protein HRI1 Peptidase_S10 PF00450.22 KII96198.1 - 1.3e-78 265.3 0.1 2.2e-78 264.6 0.1 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase PQQ_3 PF13570.6 KII96201.1 - 0.079 13.5 5.0 13 6.4 0.3 4.9 3 1 1 4 4 4 0 PQQ-like domain DUF2561 PF10812.8 KII96202.1 - 0.17 11.9 0.4 0.25 11.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DcpS_C PF11969.8 KII96203.1 - 1.2e-26 93.4 0.0 2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KII96203.1 - 2.3e-18 66.9 0.0 3.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal GFO_IDH_MocA PF01408.22 KII96205.1 - 1.1e-20 74.6 0.0 2.5e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KII96205.1 - 0.0005 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KII96205.1 - 0.053 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FIST PF08495.10 KII96207.1 - 8.9e-09 35.6 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 FIST N domain Tcf25 PF04910.14 KII96208.1 - 2.8e-104 349.0 0.0 3.5e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KII96208.1 - 0.0079 16.5 0.1 0.028 14.7 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 KII96208.1 - 0.082 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KII96208.1 - 0.57 11.2 3.9 1.1 10.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Rtf2 PF04641.12 KII96208.1 - 1.8 7.9 7.2 3.1 7.1 7.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger FAM220 PF15487.6 KII96208.1 - 4.1 7.0 5.9 7 6.2 5.9 1.4 1 0 0 1 1 1 0 FAM220 family MFS_1 PF07690.16 KII96209.1 - 1.7e-20 73.3 7.7 1.7e-20 73.3 7.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KII96209.1 - 5.7e-14 52.2 2.3 5.7e-14 52.2 2.3 2.4 3 0 0 3 3 3 1 Nodulin-like DUF4210 PF13915.6 KII96209.1 - 0.1 13.2 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) GBV-C_env PF12786.7 KII96210.1 - 0.63 8.7 5.5 0.96 8.0 5.5 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope Glyco_transf_22 PF03901.17 KII96211.1 - 8.1e-40 137.3 15.3 1e-39 137.0 15.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PPR_2 PF13041.6 KII96212.1 - 1.5e-08 34.7 1.1 9.5e-06 25.7 0.0 4.4 5 1 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KII96212.1 - 7.3e-05 22.8 0.1 0.014 15.4 0.0 3.5 3 1 1 4 4 4 1 Pentatricopeptide repeat domain KDZ PF18758.1 KII96213.1 - 5.4e-35 121.0 0.0 5.8e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase KDZ PF18758.1 KII96214.1 - 5.6e-16 58.8 0.1 8e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KII96215.1 - 2.1e-05 24.6 0.2 2.5e-05 24.4 0.2 1.1 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KII96215.1 - 0.012 15.7 0.3 0.014 15.6 0.3 1.1 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Plicaturopsis_crispa_FD-325_SS-3-Plicr1/GCA_000827205.1_Plicr1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Plicaturopsis_crispa_FD-325_SS-3-Plicr1/GCA_000827205.1_Plicr1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Plicaturopsis_crispa_FD-325_SS-3-Plicr1/GCA_000827205.1_Plicr1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Plicaturopsis_crispa_FD-325_SS-3-Plicr1/GCA_000827205.1_Plicr1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 04:15:27 2019 # [ok]